pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/374291-4-real-Parker_GPL887-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL887.an.zip classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 2,000 1,862E-07 6,793E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 55 51 3,000 1,103E-06 2,013E-03 ! cyclin-dependent protein kinase regulator activity GO:0016538 14 14 2,000 1,203E-06 1,463E-03 ! site of polarized growth GO:0030427 28 25 2,000 7,514E-06 6,852E-03 ! hemopoietic progenitor cell differentiation GO:0002244 6 5 1,000 2,311E-05 0,01685772 ! RNA polymerase II carboxy-terminal domain kinase activity GO:0008353 5 5 1,000 2,311E-05 0,0140481 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 3,462E-05 0,01804448 ! G1/S transition of mitotic cell cycle GO:0000082 54 43 2,000 3,957E-05 0,01804217 ! response to UV GO:0009411 59 45 2,000 4,54E-05 0,01840195 ! mitochondrial respiratory chain complex assembly GO:0033108 7 7 1,000 4,843E-05 0,01766659 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 7 7 1,000 4,843E-05 0,01606054 ! establishment of cell polarity GO:0030010 10 9 1,000 8,286E-05 0,0251895 ! establishment or maintenance of apical/basal cell polarity GO:0035088 10 9 1,000 8,286E-05 0,02325184 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 12 10 1,000 1,035E-04 0,02696281 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 10 10 1,000 1,035E-04 0,02516529 ! positive regulation of B cell proliferation GO:0030890 15 11 1,000 1,263E-04 0,02880751 ! Golgi vesicle budding GO:0048194 12 11 1,000 1,263E-04 0,02711295 ! response to unfolded protein GO:0006986 66 64 2,000 1,307E-04 0,02648642 ! protein kinase regulator activity GO:0019887 74 66 2,000 1,432E-04 0,02750194 ! midbody GO:0030496 14 12 1,000 1,515E-04 0,02762864 ! response to protein stimulus GO:0051789 73 70 2,000 1,706E-04 0,02964209 ! eye photoreceptor cell differentiation GO:0001754 17 13 1,000 1,788E-04 0,02965514 GO:0042462|eye photoreceptor cell development, ! regulation of B cell proliferation GO:0030888 18 14 1,000 2,084E-04 0,03306162 ! kinase regulator activity GO:0019207 93 76 2,000 2,178E-04 0,03310217 ! protein kinase C activity GO:0004697 17 15 1,000 2,403E-04 0,03506246 ! interphase of mitotic cell cycle GO:0051329 100 81 2,000 2,629E-04 0,03689191 ! gamma-aminobutyric acid signaling pathway GO:0007214 17 16 1,000 2,743E-04 0,03706749 ! photoreceptor cell development GO:0042461 22 16 1,000 2,743E-04 0,03574365 GO:0046530|photoreceptor cell differentiation, ! protein serine/threonine kinase inhibitor activity GO:0030291 17 16 1,000 2,743E-04 0,03451111 ! G2/M transition of mitotic cell cycle GO:0000086 22 16 1,000 2,743E-04 0,03336074 ! membrane budding GO:0006900 18 16 1,000 2,743E-04 0,03228459 ! interphase GO:0051325 103 83 2,000 2,826E-04 0,03221261 ! spindle microtubule GO:0005876 27 18 1,000 3,491E-04 0,03859389 ! spindle GO:0005819 126 92 2,000 3,826E-04 0,04105131 ! cellular response to unfolded protein GO:0034620 21 19 1,000 3,898E-04 0,04063047 GO:0030968|endoplasmic reticulum unfolded protein response, ! positive regulation of fibroblast proliferation GO:0048146 25 19 1,000 3,898E-04 0,03950184 ! cell cycle arrest GO:0007050 103 93 2,000 3,949E-04 0,03893974 ! negative regulation of Wnt receptor signaling pathway GO:0030178 22 21 1,000 4,778E-04 0,0458696 ! 4 iron, 4 sulfur cluster binding GO:0051539 24 21 1,000 4,778E-04 0,04469345 ! cell-cell junction organization GO:0045216 24 21 1,000 4,778E-04 0,04357612 ! response to light stimulus GO:0009416 131 100 2,000 4,886E-04 0,04347098 ! positive regulation of B cell activation GO:0050871 26 22 1,000 5,251E-04 0,04560734 ! growth cone GO:0030426 27 24 1,000 6,262E-04 0,05312248 ! GABA receptor activity GO:0016917 31 26 1,000 7,359E-04 0,06101467 ! regulation of fibroblast proliferation GO:0048145 32 26 1,000 7,359E-04 0,05965879 ! response to endoplasmic reticulum stress GO:0034976 30 26 1,000 7,359E-04 0,05836186 ! fat cell differentiation GO:0045444 30 27 1,000 7,94E-04 0,06163052 ! cyclin-dependent protein kinase activity GO:0004693 28 27 1,000 7,94E-04 0,06034655 ! negative regulation of phosphorylation GO:0042326 30 28 1,000 8,543E-04 0,0636012 ! response to heat GO:0009408 33 28 1,000 8,543E-04 0,06232917 ! establishment or maintenance of cell polarity GO:0007163 34 29 1,000 9,167E-04 0,0655705 ! ER-nuclear signaling pathway GO:0006984 32 29 1,000 9,167E-04 0,06430953 ! glutamate receptor activity GO:0008066 35 30 1,000 9,812E-04 0,06753814 ! negative regulation of phosphorus metabolic process GO:0010563 34 31 1,000 1,048E-03 0,07079099 GO:0045936|negative regulation of phosphate metabolic process, ! protein targeting to membrane GO:0006612 35 31 1,000 1,048E-03 0,06950388 ! response to calcium ion GO:0051592 34 31 1,000 1,048E-03 0,06826274 ! negative regulation of adenylate cyclase activity GO:0007194 39 32 1,000 1,117E-03 0,07146753 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of Wnt receptor signaling pathway GO:0030111 36 33 1,000 1,188E-03 0,07469492 ! regulation of B cell activation GO:0050864 40 34 1,000 1,261E-03 0,07794337 ! condensed chromosome kinetochore GO:0000777 52 34 1,000 1,261E-03 0,07664432 ! protein kinase inhibitor activity GO:0004860 37 34 1,000 1,261E-03 0,07538785 ! kinase inhibitor activity GO:0019210 47 35 1,000 1,336E-03 0,07859173 ! mitochondrial respiratory chain complex I GO:0005747 37 36 1,000 1,413E-03 0,08181536 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 36 1,000 1,413E-03 0,080537 ! cellular response to extracellular stimulus GO:0031668 37 36 1,000 1,413E-03 0,07929797 ! positive regulation of mast cell proliferation GO:0070668 43 36 1,000 1,413E-03 0,07809648 GO:0050671|positive regulation of lymphocyte proliferation, ! condensed chromosome, centromeric region GO:0000779 55 37 1,000 1,492E-03 0,08124892 ! cell junction organization GO:0034330 44 37 1,000 1,492E-03 0,08005408 ! NADH dehydrogenase (ubiquinone) activity GO:0008137 38 37 1,000 1,492E-03 0,07889388 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! positive regulation of leukocyte proliferation GO:0070665 47 37 1,000 1,492E-03 0,07776682 GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of translational initiation GO:0006446 50 38 1,000 1,574E-03 0,08085344 ! hydro-lyase activity GO:0016836 44 38 1,000 1,574E-03 0,07973048 ! induction of apoptosis by intracellular signals GO:0008629 56 41 1,000 1,83E-03 0,09146244 ! glycolysis GO:0006096 43 41 1,000 1,83E-03 0,09022646 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 43 42 1,000 1,92E-03 0,09338501 ! metal cluster binding GO:0051540 47 42 1,000 1,92E-03 0,09215626 GO:0051536|iron-sulfur cluster binding, ! positive regulation of cell cycle GO:0045787 56 43 1,000 2,012E-03 0,09530503 ! ATP synthesis coupled electron transport GO:0042773 45 44 1,000 2,105E-03 0,09846885 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! eye morphogenesis GO:0048592 57 46 1,000 2,299E-03 0,10616535 ! carbon-oxygen lyase activity GO:0016835 53 47 1,000 2,399E-03 0,10939284 ! kinetochore GO:0000776 69 48 1,000 2,501E-03 0,11263179 ! cell cortex part GO:0044448 54 48 1,000 2,501E-03 0,11125823 ! response to temperature stimulus GO:0009266 57 49 1,000 2,605E-03 0,11448533 ! regulation of mast cell proliferation GO:0070666 57 49 1,000 2,605E-03 0,11312241 ! respiratory electron transport chain GO:0022904 51 50 1,000 2,711E-03 0,11633799 ! glucose catabolic process GO:0006007 54 50 1,000 2,711E-03 0,11498522 ! aging GO:0007568 92 50 1,000 2,711E-03 0,11366355 ! regulation of lymphocyte proliferation GO:0050670 61 52 1,000 2,929E-03 0,12140396 ! vesicle organization GO:0016050 59 52 1,000 2,929E-03 0,12003987 ! N-acetyltransferase activity GO:0008080 59 53 1,000 3,041E-03 0,12324309 ! regulation of leukocyte proliferation GO:0070663 65 53 1,000 3,041E-03 0,12188877 GO:0032944|regulation of mononuclear cell proliferation, ! mitochondrial respiratory chain GO:0005746 55 54 1,000 3,154E-03 0,12508107 ! respiratory chain GO:0070469 57 55 1,000 3,27E-03 0,12828244 ! diacylglycerol binding GO:0019992 65 57 1,000 3,508E-03 0,13614343 ! actin filament organization GO:0007015 65 59 1,000 3,754E-03 0,14414055 ! hexose catabolic process GO:0019320 64 59 1,000 3,754E-03 0,14263909 ! response to metal ion GO:0010038 65 60 1,000 3,879E-03 0,14589668 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 77 62 1,000 4,137E-03 0,15398473 ! positive regulation of protein amino acid phosphorylation GO:0001934 72 62 1,000 4,137E-03 0,15242933 ! negative regulation of cell growth GO:0030308 69 63 1,000 4,268E-03 0,1557036 ! negative regulation of protein kinase activity GO:0006469 78 64 1,000 4,402E-03 0,15898267 ! N-acyltransferase activity GO:0016410 70 64 1,000 4,402E-03 0,15742402 ! negative regulation of cell size GO:0045792 71 65 1,000 4,537E-03 0,16069081 ! positive regulation of lymphocyte activation GO:0051251 83 65 1,000 4,537E-03 0,1591457 ! response to inorganic substance GO:0010035 71 65 1,000 4,537E-03 0,15763003 ! negative regulation of kinase activity GO:0033673 79 65 1,000 4,537E-03 0,15614295 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 80 65 1,000 4,537E-03 0,15468367 ! acetyltransferase activity GO:0016407 73 65 1,000 4,537E-03 0,15325142 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 83 67 1,000 4,814E-03 0,16110011 ! regulation of adenylate cyclase activity GO:0045761 81 68 1,000 4,955E-03 0,16431568 ! monosaccharide catabolic process GO:0046365 73 68 1,000 4,955E-03 0,16283536 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 84 68 1,000 4,955E-03 0,16138147 ! positive regulation of ligase activity GO:0051351 86 70 1,000 5,243E-03 0,16924877 ! regulation of cyclase activity GO:0031279 83 70 1,000 5,243E-03 0,16776413 ! negative regulation of transferase activity GO:0051348 85 70 1,000 5,243E-03 0,16630531 ! positive regulation of phosphorylation GO:0042327 82 70 1,000 5,243E-03 0,16487165 ! cell cortex GO:0005938 77 70 1,000 5,243E-03 0,16346249 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 73 71 1,000 5,389E-03 0,16661562 ! positive regulation of phosphorus metabolic process GO:0010562 85 72 1,000 5,538E-03 0,16977343 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of lyase activity GO:0051339 85 72 1,000 5,538E-03 0,16835865 ! regulation of cAMP biosynthetic process GO:0030817 86 73 1,000 5,689E-03 0,17150642 ! positive regulation of leukocyte activation GO:0002696 92 73 1,000 5,689E-03 0,17010063 ! positive regulation of cell activation GO:0050867 94 75 1,000 5,995E-03 0,17781463 ! regulation of cAMP metabolic process GO:0030814 88 75 1,000 5,995E-03 0,17638064 ! regulation of ubiquitin-protein ligase activity GO:0051438 92 75 1,000 5,995E-03 0,17496959 ! negative regulation of growth GO:0045926 85 76 1,000 6,152E-03 0,17810191 ! condensed chromosome GO:0000793 106 76 1,000 6,152E-03 0,17669954 ! alcohol catabolic process GO:0046164 84 77 1,000 6,31E-03 0,17982221 ! regulation of ligase activity GO:0051340 95 78 1,000 6,469E-03 0,1829487 ! regulation of nucleotide biosynthetic process GO:0030808 91 78 1,000 6,469E-03 0,1815414 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! positive regulation of protein modification process GO:0031401 100 78 1,000 6,469E-03 0,18015559 ! eye development GO:0001654 93 80 1,000 6,795E-03 0,18777874 ! chromosome, centromeric region GO:0000775 119 80 1,000 6,795E-03 0,18636687 ! regulation of cyclic nucleotide metabolic process GO:0030799 93 80 1,000 6,795E-03 0,18497607 ! mitochondrion organization GO:0007005 104 82 1,000 7,127E-03 0,19259192 ! cellular respiration GO:0045333 85 82 1,000 7,127E-03 0,19117581 ! oxidative phosphorylation GO:0006119 85 83 1,000 7,296E-03 0,19428052 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 101 83 1,000 7,296E-03 0,19287269 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 96 83 1,000 7,296E-03 0,19148512 ! positive regulation of epidermal growth factor receptor activity GO:0045741 6 5 0,000 7,723E-03 0,20122857 ! negative regulation of S phase of mitotic cell cycle GO:0045749 5 5 0,000 7,723E-03 0,19980142 ! positive regulation of fatty acid biosynthetic process GO:0045723 5 5 0,000 7,723E-03 0,19839437 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 6 5 0,000 7,723E-03 0,19700699 ! response to superoxide GO:0000303 5 5 0,000 7,723E-03 0,19563889 ! negative regulation of small GTPase mediated signal transduction GO:0051058 6 5 0,000 7,723E-03 0,19428965 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 6 5 0,000 7,723E-03 0,1929589 GO:0032479|regulation of type I interferon production, ! regulation of hormone biosynthetic process GO:0046885 5 5 0,000 7,723E-03 0,19164626 ! calcium:cation antiporter activity GO:0015368 5 5 0,000 7,723E-03 0,19035135 ! quinolinate metabolic process GO:0046874 5 5 0,000 7,723E-03 0,18907382 ! biotin binding GO:0009374 7 5 0,000 7,723E-03 0,18781333 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 7,723E-03 0,18656954 ! tongue development GO:0043586 6 5 0,000 7,723E-03 0,1853421 ! nose development GO:0043584 5 5 0,000 7,723E-03 0,18413072 ! cell proliferation in forebrain GO:0021846 5 5 0,000 7,723E-03 0,18293506 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 5 5 0,000 7,723E-03 0,18175484 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 7,723E-03 0,18058974 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 5 0,000 7,723E-03 0,17943949 ! drug:hydrogen antiporter activity GO:0015307 6 5 0,000 7,723E-03 0,1783038 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! nuclear mRNA 3'-splice site recognition GO:0000389 6 5 0,000 7,723E-03 0,17718239 ! glycolipid transport GO:0046836 6 5 0,000 7,723E-03 0,176075 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 6 5 0,000 7,723E-03 0,17498137 ! regulation of respiratory gaseous exchange GO:0043576 6 5 0,000 7,723E-03 0,17390123 ! regulation of protein export from nucleus GO:0046825 5 5 0,000 7,723E-03 0,17283436 ! neuron adhesion GO:0007158 5 5 0,000 7,723E-03 0,17178049 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 5 5 0,000 7,723E-03 0,17073939 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 5 0,000 7,723E-03 0,16971084 ! opioid peptide activity GO:0001515 6 5 0,000 7,723E-03 0,16869461 ! selenocysteine incorporation GO:0001514 5 5 0,000 7,723E-03 0,16769048 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 6 5 0,000 7,723E-03 0,16669822 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 8 5 0,000 7,723E-03 0,16571765 ! cardiac muscle cell proliferation GO:0060038 6 5 0,000 7,723E-03 0,16474854 GO:0014855|striated muscle cell proliferation, ! dsRNA fragmentation GO:0031050 6 5 0,000 7,723E-03 0,1637907 GO:0035196|gene silencing by miRNA, production of miRNAs, GO:0035195|gene silencing by miRNA, ! ruffle membrane GO:0032587 6 5 0,000 7,723E-03 0,16284393 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 7,723E-03 0,16190805 ! negative regulation of receptor-mediated endocytosis GO:0048261 7 5 0,000 7,723E-03 0,16098286 ! clathrin coat assembly GO:0048268 6 5 0,000 7,723E-03 0,16006818 ! cerebral cortex cell migration GO:0021795 5 5 0,000 7,723E-03 0,15916384 ! eukaryotic translation elongation factor 1 complex GO:0005853 5 5 0,000 7,723E-03 0,15826966 ! membrane hyperpolarization GO:0060081 5 5 0,000 7,723E-03 0,15738547 ! regulation of striated muscle cell differentiation GO:0051153 6 5 0,000 7,723E-03 0,15651111 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 7,723E-03 0,15564641 ! translation repressor activity GO:0030371 8 5 0,000 7,723E-03 0,15479121 ! positive regulation of muscle cell differentiation GO:0051149 6 5 0,000 7,723E-03 0,15394535 ! smooth muscle cell differentiation GO:0051145 6 5 0,000 7,723E-03 0,15310869 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 7,723E-03 0,15228108 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 5 5 0,000 7,723E-03 0,15146236 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 7,723E-03 0,15065241 GO:0046329|negative regulation of JNK cascade, ! double-stranded telomeric DNA binding GO:0003691 6 5 0,000 7,723E-03 0,14985106 ! negative regulation of heart contraction GO:0045822 5 5 0,000 7,723E-03 0,1490582 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 7,723E-03 0,14827368 ! microfibril GO:0001527 5 5 0,000 7,723E-03 0,14749738 ! troponin I binding GO:0031013 5 5 0,000 7,723E-03 0,14672917 ! negative regulation of viral genome replication GO:0045071 6 5 0,000 7,723E-03 0,14596891 ! traversing start control point of mitotic cell cycle GO:0007089 6 5 0,000 7,723E-03 0,14521649 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 7,723E-03 0,14447179 ! dorsal/ventral neural tube patterning GO:0021904 5 5 0,000 7,723E-03 0,14373469 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 7,723E-03 0,14300508 ! protein lipoylation GO:0009249 14 5 0,000 7,723E-03 0,14228283 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 7,723E-03 0,14156784 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 7,723E-03 0,14086 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of isotype switching to IgG isotypes GO:0048302 5 5 0,000 7,723E-03 0,1401592 ! transmembrane-ephrin receptor activity GO:0005005 6 5 0,000 7,723E-03 0,13946535 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 7,723E-03 0,13877832 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 7,723E-03 0,13809804 ! glutamate catabolic process GO:0006538 6 5 0,000 7,723E-03 0,13742439 ! microvillus organization GO:0032528 5 5 0,000 7,723E-03 0,13675728 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 6 5 0,000 7,723E-03 0,13609662 ! tyrosine catabolic process GO:0006572 5 5 0,000 7,723E-03 0,13544231 ! response to pH GO:0009268 5 5 0,000 7,723E-03 0,13479426 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 5 0,000 7,723E-03 0,13415238 ! regulation of protein import into nucleus, translocation GO:0033158 5 5 0,000 7,723E-03 0,13351659 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 7,723E-03 0,13288679 ! polyol biosynthetic process GO:0046173 5 5 0,000 7,723E-03 0,13226291 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 7 5 0,000 7,723E-03 0,13164486 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 7,723E-03 0,13103256 ! fibroblast growth factor receptor activity GO:0005007 6 5 0,000 7,723E-03 0,13042593 ! protein-DNA loading ATPase activity GO:0033170 6 5 0,000 7,723E-03 0,12982488 GO:0003689|DNA clamp loader activity, ! mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276 5 5 0,000 7,723E-03 0,12922936 ! anaerobic glycolysis GO:0019642 5 5 0,000 7,723E-03 0,12863927 GO:0004459|L-lactate dehydrogenase activity, ! adenosine receptor activity, G-protein coupled GO:0001609 6 5 0,000 7,723E-03 0,12805454 ! regulation of retinoic acid receptor signaling pathway GO:0048385 6 5 0,000 7,723E-03 0,12747511 ! peroxisomal matrix GO:0005782 5 5 0,000 7,723E-03 0,1269009 GO:0031907|microbody lumen, ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 7,723E-03 0,12633184 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 6 5 0,000 7,723E-03 0,12576786 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 7,723E-03 0,12520889 ! multivesicular body GO:0005771 5 5 0,000 7,723E-03 0,12465487 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 7,723E-03 0,12410573 GO:0032430|positive regulation of phospholipase A2 activity, ! paraxial mesoderm formation GO:0048341 6 5 0,000 7,723E-03 0,1235614 ! insulin-like growth factor I binding GO:0031994 6 5 0,000 7,723E-03 0,12302183 ! mitochondrial outer membrane translocase complex GO:0005742 5 5 0,000 7,723E-03 0,12248696 ! peptidyl-histidine phosphorylation GO:0018106 6 5 0,000 7,723E-03 0,12195671 ! negative regulation of lipoprotein lipase activity GO:0051005 5 5 0,000 7,723E-03 0,12143103 ! epithelial cell maturation GO:0002070 14 5 0,000 7,723E-03 0,12090987 ! positive regulation of lipoprotein lipase activity GO:0051006 6 5 0,000 7,723E-03 0,12039316 ! muscle thin filament assembly GO:0030240 5 5 0,000 7,723E-03 0,11988085 ! regulation of protein amino acid autophosphorylation GO:0031952 5 5 0,000 7,723E-03 0,11937288 ! nitric-oxide synthase regulator activity GO:0030235 6 5 0,000 7,723E-03 0,1188692 ! negative regulation of fatty acid metabolic process GO:0045922 14 5 0,000 7,723E-03 0,11836975 ! regulation of glycoprotein biosynthetic process GO:0010559 6 5 0,000 7,723E-03 0,11787448 ! cellular glucose homeostasis GO:0001678 5 5 0,000 7,723E-03 0,11738333 ! positive regulation of translational initiation GO:0045948 6 5 0,000 7,723E-03 0,11689627 ! nonhomologous end joining complex GO:0070419 6 5 0,000 7,723E-03 0,11641322 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! depyrimidination GO:0045008 5 5 0,000 7,723E-03 0,11593416 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 7,723E-03 0,11545902 ! ATPase activator activity GO:0001671 5 5 0,000 7,723E-03 0,11498775 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 7,723E-03 0,11452032 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! DNA damage response, signal transduction resulting in transcription GO:0042772 17 5 0,000 7,723E-03 0,11405668 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! calcium sensitive guanylate cyclase activator activity GO:0008048 5 5 0,000 7,723E-03 0,11359677 ! regulation of cholesterol biosynthetic process GO:0045540 5 5 0,000 7,723E-03 0,11314056 ! positive regulation of collagen metabolic process GO:0010714 6 5 0,000 7,723E-03 0,112688 GO:0032967|positive regulation of collagen biosynthetic process, ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 7 5 0,000 7,723E-03 0,11223904 ! regulation of protein amino acid dephosphorylation GO:0035304 7 5 0,000 7,723E-03 0,11179365 ! cardiac myofibril assembly GO:0055003 5 5 0,000 7,723E-03 0,11135178 ! anterograde axon cargo transport GO:0008089 6 5 0,000 7,723E-03 0,11091339 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 7,723E-03 0,11047843 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 7,723E-03 0,11004687 GO:0003923|GPI-anchor transamidase activity, ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 7,723E-03 0,10961868 ! thiamin and derivative metabolic process GO:0042723 5 5 0,000 7,723E-03 0,1091938 ! protein localization to telomere GO:0070198 7 5 0,000 7,723E-03 0,1087722 ! response to exogenous dsRNA GO:0043330 5 5 0,000 7,723E-03 0,10835385 ! MutSalpha complex binding GO:0032407 7 5 0,000 7,723E-03 0,1079387 ! bile acid biosynthetic process GO:0006699 5 5 0,000 7,723E-03 0,10752672 ! negative regulation of fat cell differentiation GO:0045599 6 5 0,000 7,723E-03 0,10711787 ! enucleate erythrocyte differentiation GO:0043353 7 5 0,000 7,723E-03 0,10671212 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 7,723E-03 0,10630943 ! nerve growth factor binding GO:0048406 7 5 0,000 7,723E-03 0,10590977 ! platelet-derived growth factor binding GO:0048407 8 5 0,000 7,723E-03 0,10551311 ! high-density lipoprotein binding GO:0008035 6 5 0,000 7,723E-03 0,1051194 ! negative regulation of focal adhesion formation GO:0051895 5 5 0,000 7,723E-03 0,10472862 ! transcription initiation factor activity GO:0016986 5 5 0,000 7,723E-03 0,10434074 ! gas homeostasis GO:0033483 5 5 0,000 7,723E-03 0,10395572 ! Schwann cell development GO:0014044 5 5 0,000 7,723E-03 0,10357353 ! CD4-positive, alpha beta T cell differentiation GO:0043367 5 5 0,000 7,723E-03 0,10319414 ! cyclohydrolase activity GO:0019238 5 5 0,000 7,723E-03 0,10281752 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 7,723E-03 0,10244364 ! response to pheromone GO:0019236 5 5 0,000 7,723E-03 0,10207246 GO:0016503|pheromone receptor activity, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 5 5 0,000 7,723E-03 0,10170397 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 7,723E-03 0,10133813 ! rhombomere development GO:0021546 6 5 0,000 7,723E-03 0,10097491 ! alanine transport GO:0032328 6 5 0,000 7,723E-03 0,10061429 ! superoxide-generating NADPH oxidase activity GO:0016175 5 5 0,000 7,723E-03 0,10025623 ! NAD(P)H oxidase activity GO:0016174 5 5 0,000 7,723E-03 0,09990071 ! ventral spinal cord interneuron specification GO:0021521 7 5 0,000 7,723E-03 0,0995477 GO:0021514|ventral spinal cord interneuron differentiation, GO:0060579|ventral spinal cord interneuron fate commitment, ! spinal cord motor neuron cell fate specification GO:0021520 6 5 0,000 7,723E-03 0,09919718 ! regulation of meiosis GO:0040020 6 5 0,000 7,723E-03 0,09884912 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 6 5 0,000 7,723E-03 0,0985035 GO:0000085|G2 phase of mitotic cell cycle, ! parasympathetic nervous system development GO:0048486 5 5 0,000 7,723E-03 0,09816028 ! lymphocyte costimulation GO:0031294 5 5 0,000 7,723E-03 0,09781944 GO:0031295|T cell costimulation, ! response to tumor cell GO:0002347 7 5 0,000 7,723E-03 0,09748097 ! RS domain binding GO:0050733 6 5 0,000 7,723E-03 0,09714483 ! telomerase holoenzyme complex GO:0005697 6 5 0,000 7,723E-03 0,096811 ! negative regulation of lipoprotein metabolic process GO:0050748 6 5 0,000 7,723E-03 0,09647945 ! B cell homeostasis GO:0001782 6 5 0,000 7,723E-03 0,09615017 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 7,723E-03 0,09582313 ! anaphase GO:0051322 7 5 0,000 7,723E-03 0,0954983 GO:0000090|mitotic anaphase, ! S phase GO:0051320 5 5 0,000 7,723E-03 0,09517568 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 7,723E-03 0,09485522 GO:0050820|positive regulation of coagulation, ! ribonuclease H activity GO:0004523 14 5 0,000 7,723E-03 0,09453691 ! AP-2 adaptor complex GO:0030122 5 5 0,000 7,723E-03 0,09422074 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 6 5 0,000 7,723E-03 0,09390667 ! diuresis GO:0030146 5 5 0,000 7,723E-03 0,09359468 GO:0030147|natriuresis, ! phosphatidylcholine binding GO:0031210 5 5 0,000 7,723E-03 0,09328477 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 7,723E-03 0,0929769 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 7,723E-03 0,09267105 ! very-low-density lipoprotein particle clearance GO:0034447 6 5 0,000 7,723E-03 0,09236721 ! GTP-Rho binding GO:0017049 5 5 0,000 7,723E-03 0,09206536 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 7,723E-03 0,09176547 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 7,723E-03 0,09146753 ! chondroitin sulfotransferase activity GO:0034481 6 5 0,000 7,723E-03 0,09117152 ! brown fat cell differentiation GO:0050873 5 5 0,000 7,723E-03 0,09087742 ! regulation of telomerase activity GO:0051972 6 5 0,000 7,723E-03 0,09058521 ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 7,723E-03 0,09029487 ! TAP complex GO:0042825 5 5 0,000 7,723E-03 0,09000639 ! platelet dense granule GO:0042827 6 5 0,000 7,723E-03 0,08971974 ! bHLH transcription factor binding GO:0043425 5 5 0,000 7,723E-03 0,08943492 ! secretory granule organization GO:0033363 5 5 0,000 7,723E-03 0,0891519 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 14 5 0,000 7,723E-03 0,08887066 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 7,723E-03 0,08859119 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 7,723E-03 0,08831348 ! lamin binding GO:0005521 8 5 0,000 7,723E-03 0,0880375 ! aldehyde-lyase activity GO:0016832 6 5 0,000 7,723E-03 0,08776324 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 7,723E-03 0,08749068 ! neural plate morphogenesis GO:0001839 6 5 0,000 7,723E-03 0,08721981 ! cyclosporin A binding GO:0016018 6 5 0,000 7,723E-03 0,08695062 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 7,723E-03 0,08668308 ! negative regulation of fibrinolysis GO:0051918 5 5 0,000 7,723E-03 0,08641718 ! positive regulation of telomere maintenance GO:0032206 7 5 0,000 7,723E-03 0,0861529 ! pattern recognition receptor signaling pathway GO:0002221 5 5 0,000 7,723E-03 0,08589024 GO:0002224|toll-like receptor signaling pathway, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 5 5 0,000 7,723E-03 0,08562918 ! positive regulation of blood vessel endothelial cell migration GO:0043536 6 5 0,000 7,723E-03 0,0853697 ! flavin-containing monooxygenase activity GO:0004499 6 5 0,000 7,723E-03 0,08511178 ! regulation of calcium ion transport via store-operated calcium channel activity GO:0032234 5 5 0,000 7,723E-03 0,08485542 ! organ or tissue specific immune response GO:0002251 6 5 0,000 7,723E-03 0,0846006 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 7,723E-03 0,0843473 ! retina homeostasis GO:0001895 5 5 0,000 7,723E-03 0,08409552 ! prepulse inhibition GO:0060134 8 5 0,000 7,723E-03 0,08384524 ! maternal placenta development GO:0001893 5 5 0,000 7,723E-03 0,08359644 GO:0046697|decidualization, ! endothelial cell development GO:0001885 6 5 0,000 7,723E-03 0,08334911 ! regulation of growth hormone secretion GO:0060123 5 5 0,000 7,723E-03 0,08310324 GO:0060124|positive regulation of growth hormone secretion, ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 7,723E-03 0,08285882 ! thiamin pyrophosphate binding GO:0030976 5 5 0,000 7,723E-03 0,08261584 ! protein palmitoylation GO:0018345 5 5 0,000 7,723E-03 0,08237427 ! protein amino acid prenylation GO:0018346 6 5 0,000 7,723E-03 0,08213411 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 5 0,000 7,723E-03 0,08189535 ! stem cell division GO:0017145 6 5 0,000 7,723E-03 0,08165797 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 7,723E-03 0,08142196 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 6 5 0,000 7,723E-03 0,08118732 ! organ regeneration GO:0031100 6 5 0,000 7,723E-03 0,08095402 ! lymphocyte apoptosis GO:0070227 6 5 0,000 7,723E-03 0,08072206 ! positive regulation of microtubule polymerization GO:0031116 5 5 0,000 7,723E-03 0,08049143 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 7,723E-03 0,08026211 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of developmental growth GO:0048639 6 5 0,000 7,723E-03 0,08003409 ! acyl carrier activity GO:0000036 5 5 0,000 7,723E-03 0,07980737 ! positive regulation of cAMP biosynthetic process GO:0030819 6 5 0,000 7,723E-03 0,07958192 GO:0030816|positive regulation of cAMP metabolic process, ! condensin complex GO:0000796 6 5 0,000 7,723E-03 0,07935775 ! phagocytic vesicle GO:0045335 5 5 0,000 7,723E-03 0,07913483 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 7,723E-03 0,07891316 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 7,723E-03 0,07869274 GO:0030823|regulation of cGMP metabolic process, ! citrulline metabolic process GO:0000052 14 5 0,000 7,723E-03 0,07847354 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 7,723E-03 0,07825556 ! polyol transport GO:0015791 8 5 0,000 7,723E-03 0,07803878 ! post-embryonic morphogenesis GO:0009886 7 5 0,000 7,723E-03 0,0778232 ! pyrimidine nucleotide-sugar transport GO:0015781 5 5 0,000 7,723E-03 0,07760882 ! regulation of cell adhesion mediated by integrin GO:0033628 5 5 0,000 7,723E-03 0,0773956 ! cell adhesion mediated by integrin GO:0033627 5 5 0,000 7,723E-03 0,07718356 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 7,723E-03 0,07697268 ! glycerol-3-phosphate metabolic process GO:0006072 6 5 0,000 7,723E-03 0,07676294 ! ethanol metabolic process GO:0006067 6 5 0,000 7,723E-03 0,07655435 GO:0006069|ethanol oxidation, GO:0034308|monohydric alcohol metabolic process, ! phosphatidic acid metabolic process GO:0046473 5 5 0,000 7,723E-03 0,07634688 ! cobalt ion transport GO:0006824 5 5 0,000 7,723E-03 0,07614054 ! cellular zinc ion homeostasis GO:0006882 6 5 0,000 7,723E-03 0,07593531 ! Golgi to plasma membrane transport GO:0006893 7 5 0,000 7,723E-03 0,07573118 ! syncytium formation by plasma membrane fusion GO:0000768 5 5 0,000 7,723E-03 0,07552815 GO:0007520|myoblast fusion, ! poly(U) RNA binding GO:0008266 5 5 0,000 7,723E-03 0,0753262 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 5 5 0,000 7,723E-03 0,07512533 ! sterol carrier activity GO:0005498 6 5 0,000 7,723E-03 0,07492553 ! adaptation of signaling pathway GO:0022401 6 5 0,000 7,723E-03 0,07472679 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 6 5 0,000 7,723E-03 0,0745291 ! response to acid GO:0001101 7 5 0,000 7,723E-03 0,07433245 ! fibril organization GO:0043206 5 5 0,000 7,723E-03 0,07413684 ! malate metabolic process GO:0006108 6 5 0,000 7,723E-03 0,07394226 ! regulation of dopamine uptake GO:0051584 7 5 0,000 7,723E-03 0,07374869 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! copulation GO:0007620 5 5 0,000 7,723E-03 0,07355614 ! circadian sleep/wake cycle process GO:0022410 5 5 0,000 7,723E-03 0,07336458 GO:0042749|regulation of circadian sleep/wake cycle, GO:0045187|regulation of circadian sleep/wake cycle, sleep, ! cleavage furrow GO:0032154 6 5 0,000 7,723E-03 0,07317403 ! protein maturation by protein folding GO:0022417 5 5 0,000 7,723E-03 0,07298446 ! activation of protein kinase B activity GO:0032148 15 5 0,000 7,723E-03 0,07279587 ! origin recognition complex GO:0000808 5 5 0,000 7,723E-03 0,07260825 ! neurexin binding GO:0042043 6 5 0,000 7,723E-03 0,07242159 ! sensory perception of temperature stimulus GO:0050951 8 5 0,000 7,723E-03 0,0722359 ! protein amino acid dealkylation GO:0008214 5 5 0,000 7,723E-03 0,07205115 GO:0006482|protein amino acid demethylation, ! NF-kappaB-inducing kinase activity GO:0004704 5 5 0,000 7,723E-03 0,07186735 ! lipoic acid binding GO:0031405 5 5 0,000 7,723E-03 0,07168448 ! very-low-density lipoprotein particle assembly GO:0034379 5 5 0,000 7,723E-03 0,07150254 ! lithium ion binding GO:0031403 6 5 0,000 7,723E-03 0,07132152 ! grooming behavior GO:0007625 7 5 0,000 7,723E-03 0,07114141 ! regulation of smooth muscle cell apoptosis GO:0034391 5 5 0,000 7,723E-03 0,07096222 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 7,723E-03 0,07078392 ! lymph vessel development GO:0001945 6 5 0,000 7,723E-03 0,07060652 ! bicarbonate transport GO:0015701 5 5 0,000 7,723E-03 0,07043 ! positive regulation of cell-matrix adhesion GO:0001954 8 5 0,000 7,723E-03 0,07025436 GO:0010811|positive regulation of cell-substrate adhesion, ! response to interferon-gamma GO:0034341 6 5 0,000 7,723E-03 0,0700796 ! protein-lysine 6-oxidase activity GO:0004720 23 5 0,000 7,723E-03 0,06990571 ! endothelial cell proliferation GO:0001935 8 5 0,000 7,723E-03 0,06973267 ! polynucleotide adenylyltransferase activity GO:0004652 5 5 0,000 7,723E-03 0,06956049 ! dorsal spinal cord development GO:0021516 6 5 0,000 7,723E-03 0,06938916 ! activation of MAPKKK activity GO:0000185 5 5 0,000 7,723E-03 0,06921867 ! synaptic vesicle maturation GO:0016188 6 5 0,000 7,723E-03 0,06904902 ! sphingoid catabolic process GO:0046521 5 5 0,000 7,723E-03 0,0688802 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 7,723E-03 0,06871219 ! neutrophil mediated immunity GO:0002446 5 5 0,000 7,723E-03 0,06854501 ! intercellular canaliculus GO:0046581 5 5 0,000 7,723E-03 0,06837864 ! dopamine binding GO:0035240 7 5 0,000 7,723E-03 0,06821307 GO:0004952|dopamine receptor activity, ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 5 5 0,000 7,723E-03 0,06804831 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 5 5 0,000 7,723E-03 0,06788434 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 6 5 0,000 7,723E-03 0,06772115 ! amine oxidase activity GO:0008131 7 5 0,000 7,723E-03 0,06755875 ! monocyte activation GO:0042117 9 5 0,000 7,723E-03 0,06739713 ! negative regulation of protein binding GO:0032091 5 5 0,000 7,723E-03 0,06723628 ! regulation of response to food GO:0032095 5 5 0,000 7,723E-03 0,06707619 ! response to food GO:0032094 6 5 0,000 7,723E-03 0,06691686 ! positive regulation of protein binding GO:0032092 5 5 0,000 7,723E-03 0,06675829 ! copper ion transmembrane transporter activity GO:0005375 5 5 0,000 7,723E-03 0,06660047 ! regulation of ryanodine-sensitive calcium-release channel activity GO:0060314 6 5 0,000 7,723E-03 0,0664434 ! hedgehog receptor activity GO:0008158 5 5 0,000 7,723E-03 0,06628706 ! lipoprotein catabolic process GO:0042159 5 5 0,000 7,723E-03 0,06613146 ! substrate-bound cell migration, cell extension GO:0006930 7 5 0,000 7,723E-03 0,06597658 ! purine salvage GO:0043101 7 5 0,000 7,723E-03 0,06582243 ! small-subunit processome GO:0032040 5 5 0,000 7,723E-03 0,065669 ! positive regulation of catecholamine secretion GO:0033605 5 5 0,000 7,723E-03 0,06551628 ! ciliary rootlet GO:0035253 5 5 0,000 7,723E-03 0,06536427 ! myosin heavy chain binding GO:0032036 5 5 0,000 7,723E-03 0,06521296 ! nucleobase transport GO:0015851 5 5 0,000 7,723E-03 0,06506236 ! sodium ion transmembrane transporter activity GO:0015081 6 5 0,000 7,723E-03 0,06491244 ! GPI anchor binding GO:0034235 6 5 0,000 7,723E-03 0,06476322 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 7,723E-03 0,06461468 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! thrombin receptor activity GO:0015057 5 5 0,000 7,723E-03 0,06446682 ! palmitoyl-CoA hydrolase activity GO:0016290 5 5 0,000 7,723E-03 0,06431963 ! basic amino acid transport GO:0015802 5 5 0,000 7,723E-03 0,06417312 ! dendritic shaft GO:0043198 5 5 0,000 7,723E-03 0,06402727 ! terminal button GO:0043195 7 5 0,000 7,723E-03 0,06388209 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 7,723E-03 0,06373756 GO:0016274|protein-arginine N-methyltransferase activity, ! neuronal ion channel clustering GO:0045161 5 5 0,000 7,723E-03 0,06359368 ! transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity GO:0030618 6 5 0,000 7,723E-03 0,06345045 ! homeostasis of number of cells within a tissue GO:0048873 7 5 0,000 7,723E-03 0,06330786 ! negative regulation of peptide secretion GO:0002792 5 5 0,000 7,723E-03 0,06316592 GO:0046676|negative regulation of insulin secretion, ! neural nucleus development GO:0048857 6 5 0,000 7,723E-03 0,06302461 ! response to UV-C GO:0010225 15 5 0,000 7,723E-03 0,06288393 ! positive regulation of organ growth GO:0046622 5 5 0,000 7,723E-03 0,06274387 ! response to arsenic GO:0046685 6 5 0,000 7,723E-03 0,06260444 ! IgE binding GO:0019863 5 5 0,000 7,723E-03 0,06246563 ! positive regulation of T cell cytokine production GO:0002726 5 5 0,000 7,723E-03 0,06232743 GO:0032743|positive regulation of interleukin-2 production, ! transcription-coupled nucleotide-excision repair GO:0006283 5 5 0,000 7,723E-03 0,06218985 ! monoamine transmembrane transporter activity GO:0008504 6 5 0,000 7,723E-03 0,06205286 ! response to copper ion GO:0046688 5 5 0,000 7,723E-03 0,06191648 ! response to cadmium ion GO:0046686 5 5 0,000 7,723E-03 0,0617807 ! tetrahydrofolate metabolic process GO:0046653 5 5 0,000 7,723E-03 0,06164551 ! regulation of interleukin-1 beta production GO:0032651 5 5 0,000 7,723E-03 0,06151092 ! protein autoprocessing GO:0016540 6 5 0,000 7,723E-03 0,06137691 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 7,723E-03 0,06124348 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 7,723E-03 0,06111063 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 7,723E-03 0,06097835 GO:0005218|intracellular ligand-gated calcium channel activity, ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 7,723E-03 0,06084665 ! mitotic recombination GO:0006312 15 5 0,000 7,723E-03 0,06071552 ! negative regulation of interleukin-6 production GO:0032715 6 5 0,000 7,723E-03 0,06058495 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 7,723E-03 0,06045494 ! membrane to membrane docking GO:0022614 5 5 0,000 7,723E-03 0,06032548 ! regulation of transcription from RNA polymerase I promoter GO:0006356 14 5 0,000 7,723E-03 0,06019658 ! translation activator activity GO:0008494 5 5 0,000 7,723E-03 0,06006823 ! somatostatin receptor activity GO:0004994 5 5 0,000 7,723E-03 0,05994043 ! melanocortin receptor activity GO:0004977 6 5 0,000 7,723E-03 0,05981316 ! serine-type carboxypeptidase activity GO:0004185 5 5 0,000 7,723E-03 0,05968644 GO:0070008|serine-type exopeptidase activity, ! protein phosphatase 2A binding GO:0051721 6 5 0,000 7,723E-03 0,05956025 ! salivary gland morphogenesis GO:0007435 5 5 0,000 7,723E-03 0,0594346 ! galactosidase activity GO:0015925 5 5 0,000 7,723E-03 0,05930947 ! prostaglandin E receptor activity GO:0004957 7 5 0,000 7,723E-03 0,05918487 ! cellular response to nutrient GO:0031670 5 5 0,000 7,723E-03 0,0590608 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 7,723E-03 0,05893724 ! L-cystine transmembrane transporter activity GO:0015184 5 5 0,000 7,723E-03 0,0588142 ! glycine transmembrane transporter activity GO:0015187 7 5 0,000 7,723E-03 0,05869167 ! L-gamma-aminobutyric acid transmembrane transporter activity GO:0015185 6 5 0,000 7,723E-03 0,05856965 ! A band GO:0031672 5 5 0,000 7,723E-03 0,05844813 ! heat generation GO:0031649 5 5 0,000 7,723E-03 0,05832712 ! flagellum organization GO:0043064 5 5 0,000 7,723E-03 0,05820661 GO:0009296|flagellum assembly, ! tricarboxylic acid cycle enzyme complex GO:0045239 6 5 0,000 7,723E-03 0,0580866 ! disaccharide metabolic process GO:0005984 6 5 0,000 7,723E-03 0,05796708 ! glycogen catabolic process GO:0005980 16 5 0,000 7,723E-03 0,05784805 ! dopamine biosynthetic process GO:0042416 6 5 0,000 7,723E-03 0,05772951 ! 5'-3' exonuclease activity GO:0008409 14 5 0,000 7,723E-03 0,05761145 ! chromocenter GO:0010369 5 5 0,000 7,723E-03 0,05749388 ! glial cell migration GO:0008347 5 5 0,000 7,723E-03 0,05737678 ! epidermal growth factor receptor binding GO:0005154 7 5 0,000 7,723E-03 0,05726016 ! calcium-dependent phospholipase A2 activity GO:0047498 5 5 0,000 7,723E-03 0,05714402 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 7,723E-03 0,05702834 ! growth hormone receptor binding GO:0005131 5 5 0,000 7,723E-03 0,05691313 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 7,723E-03 0,05679839 ! negative regulation of smooth muscle contraction GO:0045986 7 5 0,000 7,723E-03 0,0566841 ! aminomethyltransferase activity GO:0004047 5 5 0,000 7,723E-03 0,05657028 ! aminoacylase activity GO:0004046 5 5 0,000 7,723E-03 0,05645691 ! penetration of zona pellucida GO:0007341 6 5 0,000 7,723E-03 0,056344 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 5 5 0,000 7,723E-03 0,05623154 ! nucleus localization GO:0051647 5 5 0,000 7,723E-03 0,05611952 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 5 5 0,000 7,723E-03 0,05600795 ! carnitine metabolic process GO:0009437 5 5 0,000 7,723E-03 0,05589683 GO:0006577|betaine metabolic process, ! Golgi vesicle transport GO:0048193 98 86 1,000 7,814E-03 0,05644673 ! pigment granule GO:0048770 101 87 1,000 7,99E-03 0,05760564 GO:0042470|melanosome, ! protein tyrosine phosphatase activity GO:0004725 109 89 1,000 8,348E-03 0,06006656 ! protein kinase binding GO:0019901 115 89 1,000 8,348E-03 0,05994832 ! response to virus GO:0009615 109 90 1,000 8,53E-03 0,0611319 ! Ras protein signal transduction GO:0007265 118 93 1,000 9,085E-03 0,06498445 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 9,26E-03 0,0661079 ! regulation of helicase activity GO:0051095 6 6 0,000 9,26E-03 0,06597878 ! response to oxygen radical GO:0000305 6 6 0,000 9,26E-03 0,06585017 ! positive regulation of axon extension GO:0045773 7 6 0,000 9,26E-03 0,06572206 ! forebrain neuron differentiation GO:0021879 6 6 0,000 9,26E-03 0,06559444 ! forebrain regionalization GO:0021871 7 6 0,000 9,26E-03 0,06546732 ! meiotic prophase I GO:0007128 7 6 0,000 9,26E-03 0,06534069 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 9,26E-03 0,06521455 ! inositol trisphosphate phosphatase activity GO:0046030 8 6 0,000 9,26E-03 0,0650889 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 9,26E-03 0,06496373 ! SMAD protein nuclear translocation GO:0007184 7 6 0,000 9,26E-03 0,06483904 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 9 6 0,000 9,26E-03 0,06471482 ! carbohydrate phosphorylation GO:0046835 7 6 0,000 9,26E-03 0,06459109 ! phosphoinositide 3-kinase binding GO:0043548 6 6 0,000 9,26E-03 0,06446782 ! protein amino acid sulfation GO:0006477 9 6 0,000 9,26E-03 0,06434502 GO:0051923|sulfation, ! diphosphotransferase activity GO:0016778 7 6 0,000 9,26E-03 0,06422269 ! establishment of tissue polarity GO:0007164 8 6 0,000 9,26E-03 0,06410083 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 9,26E-03 0,06397943 ! receptor guanylyl cyclase signaling pathway GO:0007168 6 6 0,000 9,26E-03 0,06385848 ! embryonic camera-type eye development GO:0031076 9 6 0,000 9,26E-03 0,063738 GO:0048596|embryonic camera-type eye morphogenesis, ! hexokinase activity GO:0004396 7 6 0,000 9,26E-03 0,06361796 ! regulation of mitochondrial membrane permeability GO:0046902 7 6 0,000 9,26E-03 0,06349838 ! neurofilament cytoskeleton organization GO:0060052 6 6 0,000 9,26E-03 0,06337924 ! Notch receptor processing GO:0007220 7 6 0,000 9,26E-03 0,06326056 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 8 6 0,000 9,26E-03 0,06314231 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 7 6 0,000 9,26E-03 0,06302451 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 9,26E-03 0,06290715 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 9,26E-03 0,06279022 ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 6 0,000 9,26E-03 0,06267372 ! neurofilament GO:0005883 7 6 0,000 9,26E-03 0,06255766 ! glial cell fate commitment GO:0021781 7 6 0,000 9,26E-03 0,06244203 ! cytoplasmic dynein complex GO:0005868 7 6 0,000 9,26E-03 0,06232682 ! dynactin complex GO:0005869 7 6 0,000 9,26E-03 0,06221204 ! fibroblast growth factor receptor antagonist activity GO:0030353 7 6 0,000 9,26E-03 0,06209768 GO:0005152|interleukin-1 receptor antagonist activity, ! enoyl-CoA hydratase activity GO:0004300 6 6 0,000 9,26E-03 0,06198374 ! oocyte maturation GO:0001556 6 6 0,000 9,26E-03 0,06187022 ! DNA replication origin binding GO:0003688 6 6 0,000 9,26E-03 0,06175711 ! reflex GO:0060004 10 6 0,000 9,26E-03 0,06164441 ! positive regulation of glycolysis GO:0045821 6 6 0,000 9,26E-03 0,06153213 ! parathyroid gland development GO:0060017 6 6 0,000 9,26E-03 0,06142025 ! anagen GO:0042640 7 6 0,000 9,26E-03 0,06130878 ! protein-cofactor linkage GO:0018065 15 6 0,000 9,26E-03 0,06119771 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 6 6 0,000 9,26E-03 0,06108705 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! protein targeting to ER GO:0045047 7 6 0,000 9,26E-03 0,06097678 GO:0006614|SRP-dependent cotranslational protein targeting to membrane, ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 6 6 0,000 9,26E-03 0,06086691 ! skeletal myofibril assembly GO:0014866 6 6 0,000 9,26E-03 0,06075744 ! structural constituent of tooth enamel GO:0030345 7 6 0,000 9,26E-03 0,06064836 ! cysteine metabolic process GO:0006534 7 6 0,000 9,26E-03 0,06053967 ! glycine catabolic process GO:0006546 6 6 0,000 9,26E-03 0,06043137 ! adenohypophysis development GO:0021984 6 6 0,000 9,26E-03 0,06032346 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 6 6 0,000 9,26E-03 0,06021593 ! deoxyribonucleotide biosynthetic process GO:0009263 7 6 0,000 9,26E-03 0,06010879 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 6 0,000 9,26E-03 0,06000202 ! microtubule nucleation GO:0007020 7 6 0,000 9,26E-03 0,05989563 ! proline biosynthetic process GO:0006561 8 6 0,000 9,26E-03 0,05978962 ! tryptophan metabolic process GO:0006568 6 6 0,000 9,26E-03 0,05968399 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 6 6 0,000 9,26E-03 0,05957873 ! thyroid hormone generation GO:0006590 6 6 0,000 9,26E-03 0,05947383 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 9,26E-03 0,05936931 ! retinoid X receptor binding GO:0046965 7 6 0,000 9,26E-03 0,05926515 ! proton-transporting V-type ATPase, V0 domain GO:0033179 6 6 0,000 9,26E-03 0,05916136 ! transforming growth factor beta receptor activity, type I GO:0005025 7 6 0,000 9,26E-03 0,05905793 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 9,26E-03 0,05895486 ! sister chromatid cohesion GO:0007062 6 6 0,000 9,26E-03 0,05885216 ! retinoic acid receptor signaling pathway GO:0048384 9 6 0,000 9,26E-03 0,0587498 ! positive regulation of transporter activity GO:0032411 8 6 0,000 9,26E-03 0,05864781 GO:0032414|positive regulation of ion transmembrane transporter activity, ! cerebral cortex neuron differentiation GO:0021895 7 6 0,000 9,26E-03 0,05854617 ! regulation of fatty acid beta-oxidation GO:0031998 6 6 0,000 9,26E-03 0,05844487 ! p53 binding GO:0002039 6 6 0,000 9,26E-03 0,05834393 ! demethylase activity GO:0032451 6 6 0,000 9,26E-03 0,05824334 ! positive regulation of nitric-oxide synthase activity GO:0051000 6 6 0,000 9,26E-03 0,05814309 ! regulation of platelet activation GO:0010543 7 6 0,000 9,26E-03 0,05804319 ! lipid phosphatase activity GO:0042577 7 6 0,000 9,26E-03 0,05794363 ! lens morphogenesis in camera-type eye GO:0002089 6 6 0,000 9,26E-03 0,05784441 ! guanylate cyclase activator activity GO:0030250 6 6 0,000 9,26E-03 0,05774553 GO:0010853|cyclase activator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 8 6 0,000 9,26E-03 0,05764699 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of exocytosis GO:0045921 6 6 0,000 9,26E-03 0,05754879 ! protein tyrosine kinase activator activity GO:0030296 8 6 0,000 9,26E-03 0,05745091 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 9,26E-03 0,05735337 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of steroid metabolic process GO:0045940 6 6 0,000 9,26E-03 0,05725617 ! LIM domain binding GO:0030274 7 6 0,000 9,26E-03 0,05715929 ! negative regulation of translational initiation GO:0045947 6 6 0,000 9,26E-03 0,05706273 ! positive regulation vascular endothelial growth factor production GO:0010575 6 6 0,000 9,26E-03 0,05696651 ! 5S class rRNA transcription GO:0042791 6 6 0,000 9,26E-03 0,0568706 GO:0042797|tRNA transcription from RNA polymerase III promoter, GO:0000127|transcription factor TFIIIC complex, ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 9,26E-03 0,05677502 ! axon guidance receptor activity GO:0008046 6 6 0,000 9,26E-03 0,05667976 ! zinc ion homeostasis GO:0055069 7 6 0,000 9,26E-03 0,05658482 ! positive regulation of gliogenesis GO:0014015 7 6 0,000 9,26E-03 0,0564902 GO:0045687|positive regulation of glial cell differentiation, ! centrosome duplication GO:0051298 7 6 0,000 9,26E-03 0,05639589 ! protein targeting to lysosome GO:0006622 6 6 0,000 9,26E-03 0,0563019 ! hyaluronan metabolic process GO:0030212 8 6 0,000 9,26E-03 0,05620822 ! protein retention in ER lumen GO:0006621 6 6 0,000 9,26E-03 0,05611485 ! ventricular cardiac muscle cell differentiation GO:0055012 8 6 0,000 9,26E-03 0,05602179 ! circadian sleep/wake cycle GO:0042745 7 6 0,000 9,26E-03 0,05592904 ! dynein binding GO:0045502 6 6 0,000 9,26E-03 0,05583659 ! regulation of dendrite development GO:0050773 6 6 0,000 9,26E-03 0,05574445 ! peptidyl-arginine modification GO:0018195 6 6 0,000 9,26E-03 0,05565262 ! eating behavior GO:0042755 7 6 0,000 9,26E-03 0,05556108 ! protein localization to chromosome GO:0034502 8 6 0,000 9,26E-03 0,05546985 ! Hsp90 protein binding GO:0051879 7 6 0,000 9,26E-03 0,05537891 ! glycolipid binding GO:0051861 7 6 0,000 9,26E-03 0,05528828 ! MutLalpha complex binding GO:0032405 8 6 0,000 9,26E-03 0,05519794 ! mast cell activation GO:0045576 6 6 0,000 9,26E-03 0,05510789 ! regulation of focal adhesion formation GO:0051893 6 6 0,000 9,26E-03 0,05501814 ! nucleoside catabolic process GO:0009164 7 6 0,000 9,26E-03 0,05492868 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 9,26E-03 0,05483951 ! molybdopterin cofactor biosynthetic process GO:0032324 15 6 0,000 9,26E-03 0,05475063 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 9,26E-03 0,05466203 ! RNA polymerase II transcription elongation factor activity GO:0016944 6 6 0,000 9,26E-03 0,05457373 ! lipoxygenase activity GO:0016165 6 6 0,000 9,26E-03 0,05448571 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 9,26E-03 0,05439797 ! alpha DNA polymerase:primase complex GO:0005658 16 6 0,000 9,26E-03 0,05431051 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 9,26E-03 0,05422333 ! DNA replication factor C complex GO:0005663 7 6 0,000 9,26E-03 0,05413644 ! DNA replication factor A complex GO:0005662 7 6 0,000 9,26E-03 0,05404982 ! establishment of chromosome localization GO:0051303 15 6 0,000 9,26E-03 0,05396348 GO:0050000|chromosome localization, ! cilium morphogenesis GO:0060271 6 6 0,000 9,26E-03 0,05387741 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 9,26E-03 0,05379162 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 9,26E-03 0,0537061 ! chromatin assembly complex GO:0005678 16 6 0,000 9,26E-03 0,05362085 ! sex chromatin GO:0001739 6 6 0,000 9,26E-03 0,05353588 GO:0000803|sex chromosome, ! morphogenesis of a polarized epithelium GO:0001738 7 6 0,000 9,26E-03 0,05345117 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 7 6 0,000 9,26E-03 0,05336673 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! SAP kinase activity GO:0016909 7 6 0,000 9,26E-03 0,05328255 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 9,26E-03 0,05319864 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 7 6 0,000 9,26E-03 0,053115 ! positive regulation of pseudopodium assembly GO:0031274 6 6 0,000 9,26E-03 0,05303161 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipoprotein metabolic process GO:0050746 7 6 0,000 9,26E-03 0,05294849 ! phosphatidylserine binding GO:0001786 6 6 0,000 9,26E-03 0,05286563 ! alpha-mannosidase activity GO:0004559 8 6 0,000 9,26E-03 0,05278303 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 6 0,000 9,26E-03 0,05270068 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 9,26E-03 0,05261859 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 11 6 0,000 9,26E-03 0,05253676 GO:0002820|negative regulation of adaptive immune response, ! myeloid dendritic cell activation GO:0001773 8 6 0,000 9,26E-03 0,05245518 GO:0043011|myeloid dendritic cell differentiation, ! immunological synapse GO:0001772 6 6 0,000 9,26E-03 0,05237386 ! leading edge membrane GO:0031256 8 6 0,000 9,26E-03 0,05229278 ! photoreceptor connecting cilium GO:0032391 7 6 0,000 9,26E-03 0,05221196 ! CARD domain binding GO:0050700 6 6 0,000 9,26E-03 0,05213139 ! regulation of muscle cell apoptosis GO:0010660 7 6 0,000 9,26E-03 0,05205106 ! COPII vesicle coat GO:0030127 7 6 0,000 9,26E-03 0,05197098 GO:0012507|ER to Golgi transport vesicle membrane, ! molybdenum ion binding GO:0030151 15 6 0,000 9,26E-03 0,05189115 ! glutathione biosynthetic process GO:0006750 7 6 0,000 9,26E-03 0,05181156 ! positive regulation of erythrocyte differentiation GO:0045648 8 6 0,000 9,26E-03 0,05173222 ! positive regulation of epidermis development GO:0045684 8 6 0,000 9,26E-03 0,05165312 ! proteasome regulator activity GO:0010860 6 6 0,000 9,26E-03 0,05157426 ! ceramidase activity GO:0017040 6 6 0,000 9,26E-03 0,05149564 ! antibiotic transport GO:0042891 7 6 0,000 9,26E-03 0,05141726 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 9,26E-03 0,05133911 ! regulation of T-helper cell differentiation GO:0045622 6 6 0,000 9,26E-03 0,05126121 ! sodium channel regulator activity GO:0017080 6 6 0,000 9,26E-03 0,05118354 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 9,26E-03 0,05110611 ! regulation of protein homodimerization activity GO:0043496 9 6 0,000 9,26E-03 0,05102891 ! response to fluid shear stress GO:0034405 6 6 0,000 9,26E-03 0,05095194 ! lymph node development GO:0048535 6 6 0,000 9,26E-03 0,05087521 ! negative regulation of viral reproduction GO:0048525 7 6 0,000 9,26E-03 0,0507987 ! triglyceride catabolic process GO:0019433 15 6 0,000 9,26E-03 0,05072243 ! positive regulation of fatty acid oxidation GO:0046321 6 6 0,000 9,26E-03 0,05064638 ! ectodermal gut morphogenesis GO:0048567 7 6 0,000 9,26E-03 0,05057057 GO:0007439|ectodermal gut development, ! T cell activation during immune response GO:0002286 6 6 0,000 9,26E-03 0,05049497 ! negative regulation of lipase activity GO:0060192 6 6 0,000 9,26E-03 0,05041961 ! activation of innate immune response GO:0002218 6 6 0,000 9,26E-03 0,05034447 GO:0002758|innate immune response-activating signal transduction, ! regulation of telomere maintenance via telomerase GO:0032210 7 6 0,000 9,26E-03 0,05026955 ! sarcoglycan complex GO:0016012 8 6 0,000 9,26E-03 0,05019486 ! natural killer cell mediated immunity GO:0002228 7 6 0,000 9,26E-03 0,05012038 GO:0042267|natural killer cell mediated cytotoxicity, ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 6 6 0,000 9,26E-03 0,05004613 ! neural plate development GO:0001840 7 6 0,000 9,26E-03 0,0499721 ! regulation of synaptic transmission, GABAergic GO:0032228 15 6 0,000 9,26E-03 0,04989828 ! catecholamine transport GO:0051937 6 6 0,000 9,26E-03 0,04982469 ! ether hydrolase activity GO:0016803 7 6 0,000 9,26E-03 0,04975131 ! FACIT collagen GO:0005593 6 6 0,000 9,26E-03 0,04967814 ! lactate dehydrogenase activity GO:0004457 6 6 0,000 9,26E-03 0,04960519 ! regulation of T cell receptor signaling pathway GO:0050856 7 6 0,000 9,26E-03 0,04953246 ! collagen type IV GO:0005587 6 6 0,000 9,26E-03 0,04945994 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 9,26E-03 0,04938763 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 7 6 0,000 9,26E-03 0,04931553 ! drug metabolic process GO:0017144 6 6 0,000 9,26E-03 0,04924364 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 9,26E-03 0,04917196 ! negative regulation of synaptic transmission GO:0050805 6 6 0,000 9,26E-03 0,04910049 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 9,26E-03 0,04902923 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 9,26E-03 0,04895817 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 6 6 0,000 9,26E-03 0,04888732 ! regulation of microtubule polymerization GO:0031113 6 6 0,000 9,26E-03 0,04881667 ! cellular anion homeostasis GO:0030002 6 6 0,000 9,26E-03 0,04874623 GO:0055081|anion homeostasis, ! regulation of MHC class II biosynthetic process GO:0045346 6 6 0,000 9,26E-03 0,04867599 ! negative regulation of protein ubiquitination GO:0031397 7 6 0,000 9,26E-03 0,04860595 ! negative regulation of fibroblast proliferation GO:0048147 6 6 0,000 9,26E-03 0,04853612 ! behavioral response to cocaine GO:0048148 9 6 0,000 9,26E-03 0,04846648 ! translation initiation factor binding GO:0031369 6 6 0,000 9,26E-03 0,04839705 ! nucleotide-sugar transport GO:0015780 6 6 0,000 9,26E-03 0,04832781 ! sulfur amino acid transmembrane transporter activity GO:0000099 6 6 0,000 9,26E-03 0,04825877 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 9,26E-03 0,04818993 ! quaternary ammonium group binding GO:0050997 7 6 0,000 9,26E-03 0,04812128 ! actin-dependent ATPase activity GO:0030898 7 6 0,000 9,26E-03 0,04805283 ! reproductive behavior GO:0019098 8 6 0,000 9,26E-03 0,04798457 ! response to growth hormone stimulus GO:0060416 7 6 0,000 9,26E-03 0,04791651 GO:0060396|growth hormone receptor signaling pathway, ! negative regulation of JAK-STAT cascade GO:0046426 8 6 0,000 9,26E-03 0,04784864 ! nucleotide-excision repair, DNA incision GO:0033683 6 6 0,000 9,26E-03 0,04778096 ! negative regulation of cell-cell adhesion GO:0022408 8 6 0,000 9,26E-03 0,04771347 ! positive regulation of cell-cell adhesion GO:0022409 7 6 0,000 9,26E-03 0,04764617 ! induction of positive chemotaxis GO:0050930 7 6 0,000 9,26E-03 0,04757907 ! cohesin complex GO:0008278 6 6 0,000 9,26E-03 0,04751215 ! regulation of collagen biosynthetic process GO:0032965 7 6 0,000 9,26E-03 0,04744542 ! citrate metabolic process GO:0006101 7 6 0,000 9,26E-03 0,04737887 ! myelin sheath GO:0043209 8 6 0,000 9,26E-03 0,04731252 ! phototransduction, visible light GO:0007603 6 6 0,000 9,26E-03 0,04724635 ! opsonization GO:0008228 7 6 0,000 9,26E-03 0,04718036 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 9,26E-03 0,04711456 ! regulation of dopamine metabolic process GO:0042053 8 6 0,000 9,26E-03 0,04704894 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 7 6 0,000 9,26E-03 0,0469835 ! regulation of potassium ion transport GO:0043266 8 6 0,000 9,26E-03 0,04691825 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 9,26E-03 0,04685317 ! chemoattractant activity GO:0042056 6 6 0,000 9,26E-03 0,04678828 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 8 6 0,000 9,26E-03 0,04672357 ! low-density lipoprotein particle remodeling GO:0034374 6 6 0,000 9,26E-03 0,04665903 ! ornithine decarboxylase regulator activity GO:0042979 6 6 0,000 9,26E-03 0,04659467 ! leukocyte degranulation GO:0043299 6 6 0,000 9,26E-03 0,04653049 ! bile acid and bile salt transport GO:0015721 7 6 0,000 9,26E-03 0,04646649 ! regulation of cytokine-mediated signaling pathway GO:0001959 11 6 0,000 9,26E-03 0,04640266 ! mitochondrial genome maintenance GO:0000002 6 6 0,000 9,26E-03 0,04633901 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 6 0,000 9,26E-03 0,04627553 ! DNA topoisomerase activity GO:0003916 6 6 0,000 9,26E-03 0,04621223 ! protein geranylgeranyltransferase activity GO:0004661 7 6 0,000 9,26E-03 0,0461491 ! ceramide biosynthetic process GO:0046513 6 6 0,000 9,26E-03 0,04608614 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 9,26E-03 0,04602335 ! activin receptor activity GO:0017002 7 6 0,000 9,26E-03 0,04596073 ! astrocyte differentiation GO:0048708 6 6 0,000 9,26E-03 0,04589828 ! syncytium formation GO:0006949 6 6 0,000 9,26E-03 0,04583601 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 9,26E-03 0,0457739 ! neutrophil activation GO:0042119 6 6 0,000 9,26E-03 0,04571196 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 9,26E-03 0,04565019 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 9,26E-03 0,04558858 ! positive regulation of activated T cell proliferation GO:0042104 7 6 0,000 9,26E-03 0,04552714 ! positive transcription elongation factor activity GO:0008159 7 6 0,000 9,26E-03 0,04546586 ! NuA4 histone acetyltransferase complex GO:0035267 8 6 0,000 9,26E-03 0,04540475 ! cellular polysaccharide catabolic process GO:0044247 17 6 0,000 9,26E-03 0,04534381 GO:0009251|glucan catabolic process, ! response to salt stress GO:0009651 7 6 0,000 9,26E-03 0,04528303 ! neuron apoptosis GO:0051402 7 6 0,000 9,26E-03 0,04522241 ! folic acid transport GO:0015884 8 6 0,000 9,26E-03 0,04516195 ! carnitine transport GO:0015879 6 6 0,000 9,26E-03 0,04510165 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 9,26E-03 0,04504152 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! parturition GO:0007567 7 6 0,000 9,26E-03 0,04498154 ! S-methyltransferase activity GO:0008172 6 6 0,000 9,26E-03 0,04492173 ! phospholipase D activity GO:0004630 6 6 0,000 9,26E-03 0,04486207 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 9,26E-03 0,04480257 ! intercalated disc GO:0014704 8 6 0,000 9,26E-03 0,04474323 ! G2/M transition checkpoint GO:0031576 24 6 0,000 9,26E-03 0,04468404 GO:0031572|G2/M transition DNA damage checkpoint, ! interaction with symbiont GO:0051702 6 6 0,000 9,26E-03 0,04462502 ! IgG binding GO:0019864 6 6 0,000 9,26E-03 0,04456614 ! regulation of T cell cytokine production GO:0002724 6 6 0,000 9,26E-03 0,04450743 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 6 6 0,000 9,26E-03 0,04444887 ! benzodiazepine receptor activity GO:0008503 7 6 0,000 9,26E-03 0,04439046 ! antigen processing and presentation of exogenous antigen GO:0019884 7 6 0,000 9,26E-03 0,0443322 ! regulation of T cell differentiation in the thymus GO:0033081 7 6 0,000 9,26E-03 0,0442741 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 6 6 0,000 9,26E-03 0,04421615 ! regulation of interleukin-4 production GO:0032673 6 6 0,000 9,26E-03 0,04415835 ! dendrite morphogenesis GO:0048813 7 6 0,000 9,26E-03 0,0441007 ! regulation of interleukin-1 production GO:0032652 7 6 0,000 9,26E-03 0,0440432 ! ribosomal large subunit biogenesis GO:0042273 7 6 0,000 9,26E-03 0,04398586 ! regulation of myeloid cell apoptosis GO:0033032 8 6 0,000 9,26E-03 0,04392866 ! nucleosome disassembly GO:0006337 7 6 0,000 9,26E-03 0,04387161 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! general transcriptional repressor activity GO:0016565 7 6 0,000 9,26E-03 0,04381471 ! regulation of mast cell activation GO:0033003 6 6 0,000 9,26E-03 0,04375795 ! tetracycline transporter activity GO:0008493 7 6 0,000 9,26E-03 0,04370134 GO:0042895|antibiotic transporter activity, ! guanylyltransferase activity GO:0070568 7 6 0,000 9,26E-03 0,04364488 ! receptor internalization GO:0031623 8 6 0,000 9,26E-03 0,04358856 ! N-formyl peptide receptor activity GO:0004982 6 6 0,000 9,26E-03 0,04353239 ! coenzyme A biosynthetic process GO:0015937 6 6 0,000 9,26E-03 0,04347637 ! histamine receptor activity GO:0004969 7 6 0,000 9,26E-03 0,04342049 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 6 0,000 9,26E-03 0,04336475 ! pyrimidine nucleotide sugar transmembrane transporter activity GO:0015165 6 6 0,000 9,26E-03 0,04330915 ! protein deubiquitination GO:0016579 6 6 0,000 9,26E-03 0,0432537 ! axonal fasciculation GO:0007413 7 6 0,000 9,26E-03 0,04319839 ! basic amino acid transmembrane transporter activity GO:0015174 6 6 0,000 9,26E-03 0,04314322 ! cytidine deaminase activity GO:0004126 6 6 0,000 9,26E-03 0,04308819 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 9,26E-03 0,0430333 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 9,26E-03 0,04297855 GO:0015991|ATP hydrolysis coupled proton transport, ! alpha-adrenergic receptor activity GO:0004936 9 6 0,000 9,26E-03 0,04292394 ! cytochrome-b5 reductase activity GO:0004128 7 6 0,000 9,26E-03 0,04286946 ! glycine binding GO:0016594 9 6 0,000 9,26E-03 0,04281513 ! apical protein localization GO:0045176 7 6 0,000 9,26E-03 0,04276093 ! ankyrin binding GO:0030506 6 6 0,000 9,26E-03 0,04270687 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 9,26E-03 0,04265295 ! thyroid hormone receptor activity GO:0004887 7 6 0,000 9,26E-03 0,04259916 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 9,26E-03 0,04254551 ! progesterone metabolic process GO:0042448 6 6 0,000 9,26E-03 0,042492 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 7 6 0,000 9,26E-03 0,04243862 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 9,26E-03 0,04238537 ! type II transforming growth factor beta receptor binding GO:0005114 6 6 0,000 9,26E-03 0,04233225 ! ATP catabolic process GO:0006200 6 6 0,000 9,26E-03 0,04227927 ! CoA carboxylase activity GO:0016421 6 6 0,000 9,26E-03 0,04222642 ! determination of adult lifespan GO:0008340 6 6 0,000 9,26E-03 0,0421737 ! S-acyltransferase activity GO:0016417 6 6 0,000 9,26E-03 0,04212112 ! somatic stem cell maintenance GO:0035019 6 6 0,000 9,26E-03 0,04206866 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 9,26E-03 0,04201634 ! IkappaB kinase complex GO:0008385 7 6 0,000 9,26E-03 0,04196415 ! nucleobase transmembrane transporter activity GO:0015205 7 6 0,000 9,26E-03 0,04191208 ! store-operated calcium channel activity GO:0015279 6 6 0,000 9,26E-03 0,04186015 ! alkaline phosphatase activity GO:0004035 7 6 0,000 9,26E-03 0,04180834 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 6 0,000 9,26E-03 0,04175666 ! unconventional myosin complex GO:0016461 8 6 0,000 9,26E-03 0,04170511 ! carbohydrate catabolic process GO:0016052 116 96 1,000 9,656E-03 0,0434349 ! electron transport chain GO:0022900 104 97 1,000 9,85E-03 0,04425243 ! regulation of lymphocyte activation GO:0051249 123 100 1,000 0,01044208 0,0468545 ! tRNA transcription GO:0009304 7 7 0,000 0,01079547 0,04838069 ! respiratory burst GO:0045730 7 7 0,000 0,01079547 0,04832133 ! telencephalon cell migration GO:0022029 8 7 0,000 0,01079547 0,04826211 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 0,01079547 0,04820304 ! cation:chloride symporter activity GO:0015377 8 7 0,000 0,01079547 0,04814411 ! RNA cap binding GO:0000339 8 7 0,000 0,01079547 0,04808533 ! generation of neurons in the forebrain GO:0021872 8 7 0,000 0,01079547 0,04802669 ! ephrin receptor binding GO:0046875 9 7 0,000 0,01079547 0,04796819 ! male meiosis I GO:0007141 7 7 0,000 0,01079547 0,04790983 ! synapsis GO:0007129 7 7 0,000 0,01079547 0,04785162 GO:0070192|chromosome organization involved in meiosis, ! insulin receptor substrate binding GO:0043560 10 7 0,000 0,01079547 0,04779355 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 0,01079547 0,04773562 ! type I transforming growth factor beta receptor binding GO:0034713 8 7 0,000 0,01079547 0,04767782 ! signal peptide processing GO:0006465 7 7 0,000 0,01079547 0,04762017 ! regulation of cardiac muscle cell proliferation GO:0060043 8 7 0,000 0,01079547 0,04756266 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 0,01079547 0,04750529 ! macrophage chemotaxis GO:0048246 7 7 0,000 0,01079547 0,04744805 ! Golgi cisterna membrane GO:0032580 7 7 0,000 0,01079547 0,04739095 ! neurofilament cytoskeleton GO:0060053 8 7 0,000 0,01079547 0,04733399 ! positive regulation of receptor-mediated endocytosis GO:0048260 7 7 0,000 0,01079547 0,04727717 ! smoothened signaling pathway GO:0007224 8 7 0,000 0,01079547 0,04722048 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 0,01079547 0,04716393 ! oxidoreductase activity, oxidizing metal ions GO:0016722 7 7 0,000 0,01079547 0,04710752 ! cytoplasmic microtubule GO:0005881 7 7 0,000 0,01079547 0,04705123 ! Arp2/3 protein complex GO:0005885 8 7 0,000 0,01079547 0,04699509 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 7 7 0,000 0,01079547 0,04693907 ! ATPase binding GO:0051117 8 7 0,000 0,01079547 0,04688319 ! positive regulation of isotype switching GO:0045830 7 7 0,000 0,01079547 0,04682745 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01079547 0,04677183 ! positive regulation of gene expression, epigenetic GO:0045815 7 7 0,000 0,01079547 0,04671635 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 7 0,000 0,01079547 0,046661 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01079547 0,04660578 ! thymic T cell selection GO:0045061 16 7 0,000 0,01079547 0,04655069 ! transepithelial chloride transport GO:0030321 7 7 0,000 0,01079547 0,04649573 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 0,01079547 0,0464409 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 7 7 0,000 0,01079547 0,0463862 ! negative regulation of survival gene product expression GO:0008634 9 7 0,000 0,01079547 0,04633163 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 0,01079547 0,04627718 ! melanocyte differentiation GO:0030318 8 7 0,000 0,01079547 0,04622287 ! malate dehydrogenase activity GO:0016615 8 7 0,000 0,01079547 0,04616868 ! DNA secondary structure binding GO:0000217 16 7 0,000 0,01079547 0,04611462 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 8 7 0,000 0,01079547 0,04606068 ! regulation of peptidyl-serine phosphorylation GO:0033135 7 7 0,000 0,01079547 0,04600687 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 0,01079547 0,04595319 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 0,01079547 0,04589963 GO:0021940|positive regulation of granule cell precursor proliferation, ! V(D)J recombination GO:0033151 8 7 0,000 0,01079547 0,0458462 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 0,01079547 0,04579289 ! vascular endothelial growth factor receptor activity GO:0005021 12 7 0,000 0,01079547 0,0457397 ! central nervous system neuron axonogenesis GO:0021955 8 7 0,000 0,01079547 0,04568664 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 0,01079547 0,0456337 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! response to tumor necrosis factor GO:0034612 8 7 0,000 0,01079547 0,04558088 ! peptidoglycan metabolic process GO:0000270 9 7 0,000 0,01079547 0,04552819 GO:0009253|peptidoglycan catabolic process, ! response to ATP GO:0033198 7 7 0,000 0,01079547 0,04547562 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 8 7 0,000 0,01079547 0,04542316 GO:0048500|signal recognition particle, ! stereocilium GO:0032420 10 7 0,000 0,01079547 0,04537083 ! paraxial mesoderm morphogenesis GO:0048340 9 7 0,000 0,01079547 0,04531862 ! melanosome organization GO:0032438 7 7 0,000 0,01079547 0,04526653 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 8 7 0,000 0,01079547 0,04521456 ! mesodermal cell differentiation GO:0048333 9 7 0,000 0,01079547 0,04516271 GO:0001710|mesodermal cell fate commitment, ! positive regulation of neuroblast proliferation GO:0002052 7 7 0,000 0,01079547 0,04511098 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01079547 0,04505936 ! chondrocyte differentiation GO:0002062 7 7 0,000 0,01079547 0,04500787 ! guanylate cyclase regulator activity GO:0030249 7 7 0,000 0,01079547 0,04495649 GO:0010851|cyclase regulator activity, ! intestinal cholesterol absorption GO:0030299 9 7 0,000 0,01079547 0,04490523 ! negative regulation of specific transcription from RNA polymerase II promoter GO:0010553 8 7 0,000 0,01079547 0,04485408 ! positive regulation of mitotic cell cycle GO:0045931 7 7 0,000 0,01079547 0,04480305 ! determination of anterior/posterior axis, embryo GO:0008595 10 7 0,000 0,01079547 0,04475214 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 8 7 0,000 0,01079547 0,04470134 ! regulation of vascular endothelial growth factor production GO:0010574 7 7 0,000 0,01079547 0,04465066 ! Schwann cell differentiation GO:0014037 8 7 0,000 0,01079547 0,04460009 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 9 7 0,000 0,01079547 0,04454964 ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 0,01079547 0,0444993 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 0,01079547 0,04444908 ! vinculin binding GO:0017166 9 7 0,000 0,01079547 0,04439897 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 0,01079547 0,04434897 ! regulation of collagen metabolic process GO:0010712 8 7 0,000 0,01079547 0,04429908 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 0,01079547 0,04424931 ! negative regulation of gliogenesis GO:0014014 8 7 0,000 0,01079547 0,04419964 GO:0045686|negative regulation of glial cell differentiation, ! translation termination factor activity GO:0008079 7 7 0,000 0,01079547 0,04415009 GO:0003747|translation release factor activity, ! purine base biosynthetic process GO:0009113 8 7 0,000 0,01079547 0,04410065 ! cardiac muscle cell development GO:0055013 8 7 0,000 0,01079547 0,04405132 ! fibrinolysis GO:0042730 9 7 0,000 0,01079547 0,0440021 ! response to tropane GO:0014073 10 7 0,000 0,01079547 0,04395299 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 7 7 0,000 0,01079547 0,04390399 GO:0051904|pigment granule transport, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 8 7 0,000 0,01079547 0,0438551 ! glycosylceramide metabolic process GO:0006677 7 7 0,000 0,01079547 0,04380632 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 7 7 0,000 0,01079547 0,04375765 ! laminin-1 complex GO:0005606 7 7 0,000 0,01079547 0,04370908 GO:0043256|laminin complex, ! regulation of chondrocyte differentiation GO:0032330 8 7 0,000 0,01079547 0,04366062 ! positive regulation of immunoglobulin mediated immune response GO:0002891 7 7 0,000 0,01079547 0,04361227 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of lipid transport GO:0032370 8 7 0,000 0,01079547 0,04356403 ! regulation of cell division GO:0051302 7 7 0,000 0,01079547 0,04351589 ! holo TFIIH complex GO:0005675 7 7 0,000 0,01079547 0,04346786 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 7 0,000 0,01079547 0,04341994 ! chitinase activity GO:0004568 7 7 0,000 0,01079547 0,04337212 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 8 7 0,000 0,01079547 0,0433244 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! U12-type spliceosomal complex GO:0005689 8 7 0,000 0,01079547 0,04327679 ! regulation of respiratory burst GO:0060263 8 7 0,000 0,01079547 0,04322929 ! prophase GO:0051324 8 7 0,000 0,01079547 0,04318189 ! peptidyl-histidine modification GO:0018202 8 7 0,000 0,01079547 0,04313459 ! centriolar satellite GO:0034451 10 7 0,000 0,01079547 0,0430874 ! BBSome GO:0034464 7 7 0,000 0,01079547 0,04304031 ! glycerophosphodiester phosphodiesterase activity GO:0008889 7 7 0,000 0,01079547 0,04299332 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01079547 0,04294644 ! negative regulation of lymphocyte differentiation GO:0045620 8 7 0,000 0,01079547 0,04289965 ! negative regulation of transmission of nerve impulse GO:0051970 7 7 0,000 0,01079547 0,04285297 ! regulation of synaptic transmission, glutamatergic GO:0051966 8 7 0,000 0,01079547 0,04280639 ! regulation of synaptogenesis GO:0051963 7 7 0,000 0,01079547 0,04275992 ! serine family amino acid catabolic process GO:0009071 7 7 0,000 0,01079547 0,04271354 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 0,01079547 0,04266726 ! glycolipid catabolic process GO:0019377 7 7 0,000 0,01079547 0,04262109 GO:0046479|glycosphingolipid catabolic process, ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 8 7 0,000 0,01079547 0,04257501 ! circadian behavior GO:0048512 9 7 0,000 0,01079547 0,04252903 ! dorsal/ventral axis specification GO:0009950 7 7 0,000 0,01079547 0,04248315 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 7 0,000 0,01079547 0,04243737 ! striatum development GO:0021756 7 7 0,000 0,01079547 0,04239169 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 8 7 0,000 0,01079547 0,04234611 ! triglyceride biosynthetic process GO:0019432 7 7 0,000 0,01079547 0,04230063 ! cerebellar Purkinje cell layer development GO:0021680 7 7 0,000 0,01079547 0,04225524 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 0,01079547 0,04220995 ! dystroglycan complex GO:0016011 9 7 0,000 0,01079547 0,04216476 ! negative regulation of calcium ion transport GO:0051926 7 7 0,000 0,01079547 0,04211966 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 7 0,000 0,01079547 0,04207466 ! peroxiredoxin activity GO:0051920 7 7 0,000 0,01079547 0,04202976 ! muscle adaptation GO:0043500 7 7 0,000 0,01079547 0,04198495 ! regulation of muscle adaptation GO:0043502 7 7 0,000 0,01079547 0,04194024 ! diacylglycerol metabolic process GO:0046339 7 7 0,000 0,01079547 0,04189562 ! lysogeny GO:0030069 7 7 0,000 0,01079547 0,0418511 GO:0019047|provirus integration, ! protein insertion into membrane GO:0051205 7 7 0,000 0,01079547 0,04180667 ! sequestering of metal ion GO:0051238 9 7 0,000 0,01079547 0,04176234 ! membrane attack complex GO:0005579 7 7 0,000 0,01079547 0,0417181 ! fibrinogen complex GO:0005577 7 7 0,000 0,01079547 0,04167395 ! metallo-sulfur cluster assembly GO:0031163 9 7 0,000 0,01079547 0,0416299 GO:0016226|iron-sulfur cluster assembly, ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 7 0,000 0,01079547 0,04158594 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 7 0,000 0,01079547 0,04154207 ! GABA receptor binding GO:0050811 8 7 0,000 0,01079547 0,0414983 ! sheet-forming collagen GO:0030935 7 7 0,000 0,01079547 0,04145461 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 8 7 0,000 0,01079547 0,04141102 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 8 7 0,000 0,01079547 0,04136752 ! sphingomyelin phosphodiesterase activity GO:0004767 9 7 0,000 0,01079547 0,04132412 ! regulation of epithelial cell differentiation GO:0030856 7 7 0,000 0,01079547 0,0412808 ! 7S RNA binding GO:0008312 8 7 0,000 0,01079547 0,04123757 ! positive regulation of lipid catabolic process GO:0050996 7 7 0,000 0,01079547 0,04119444 ! protein phosphorylated amino acid binding GO:0045309 9 7 0,000 0,01079547 0,04115139 ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 8 7 0,000 0,01079547 0,04110844 ! regulation of long-term neuronal synaptic plasticity GO:0048169 17 7 0,000 0,01079547 0,04106557 ! Golgi to endosome transport GO:0006895 8 7 0,000 0,01079547 0,04102279 ! glucocorticoid receptor signaling pathway GO:0042921 7 7 0,000 0,01079547 0,04098011 GO:0031958|corticosteroid receptor signaling pathway, ! succinate metabolic process GO:0006105 7 7 0,000 0,01079547 0,04093751 ! fibril GO:0043205 7 7 0,000 0,01079547 0,040895 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01079547 0,04085258 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01079547 0,04081024 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 7 0,000 0,01079547 0,04076799 ! sensory perception of bitter taste GO:0050913 7 7 0,000 0,01079547 0,04072584 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01079547 0,04068376 ! posttranscriptional gene silencing by RNA GO:0035194 9 7 0,000 0,01079547 0,04064178 GO:0016441|posttranscriptional gene silencing, ! cell division site part GO:0032155 9 7 0,000 0,01079547 0,04059988 GO:0032153|cell division site, ! laminin binding GO:0043236 7 7 0,000 0,01079547 0,04055807 ! equilibrioception GO:0050957 10 7 0,000 0,01079547 0,04051634 ! G-protein coupled receptor kinase activity GO:0004703 9 7 0,000 0,01079547 0,0404747 ! titin binding GO:0031432 7 7 0,000 0,01079547 0,04043314 ! chemosensory behavior GO:0007635 9 7 0,000 0,01079547 0,04039167 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 0,01079547 0,04035029 GO:0032107|regulation of response to nutrient levels, ! plasma lipoprotein particle assembly GO:0034377 7 7 0,000 0,01079547 0,04030899 ! cobalamin binding GO:0031419 7 7 0,000 0,01079547 0,04026777 ! sodium:phosphate symporter activity GO:0005436 8 7 0,000 0,01079547 0,04022664 ! response to axon injury GO:0048678 9 7 0,000 0,01079547 0,04018559 ! regulation of activin receptor signaling pathway GO:0032925 7 7 0,000 0,01079547 0,04014463 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 0,01079547 0,04010375 ! F-actin capping protein complex GO:0008290 8 7 0,000 0,01079547 0,04006295 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 0,01079547 0,04002224 ! cGMP-mediated signaling GO:0019934 8 7 0,000 0,01079547 0,03998161 ! nerve growth factor receptor signaling pathway GO:0048011 8 7 0,000 0,01079547 0,03994106 ! cAMP-dependent protein kinase activity GO:0004691 7 7 0,000 0,01079547 0,03990059 ! senescence GO:0010149 8 7 0,000 0,01079547 0,03986021 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 10 7 0,000 0,01079547 0,0398199 ! nuclear localization sequence binding GO:0008139 8 7 0,000 0,01079547 0,03977968 ! galactose metabolic process GO:0006012 8 7 0,000 0,01079547 0,03973954 ! vesicle fusion GO:0006906 8 7 0,000 0,01079547 0,03969948 ! maintenance of protein location in nucleus GO:0051457 7 7 0,000 0,01079547 0,0396595 ! intracellular pH reduction GO:0051452 7 7 0,000 0,01079547 0,0396196 ! glycerol ether catabolic process GO:0044269 16 7 0,000 0,01079547 0,03957978 GO:0046461|neutral lipid catabolic process, GO:0046464|acylglycerol catabolic process, ! neurotransmitter catabolic process GO:0042135 9 7 0,000 0,01079547 0,03954004 ! ruffle organization GO:0031529 9 7 0,000 0,01079547 0,03950038 ! nucleoside transport GO:0015858 8 7 0,000 0,01079547 0,0394608 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 0,01079547 0,0394213 ! inclusion body GO:0016234 7 7 0,000 0,01079547 0,03938188 ! Cajal body GO:0015030 7 7 0,000 0,01079547 0,03934254 ! H4/H2A histone acetyltransferase complex GO:0043189 9 7 0,000 0,01079547 0,03930328 ! rRNA modification GO:0000154 7 7 0,000 0,01079547 0,03926409 ! PcG protein complex GO:0031519 7 7 0,000 0,01079547 0,03922498 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 0,01079547 0,03918595 ! NAD-dependent protein deacetylase activity GO:0034979 7 7 0,000 0,01079547 0,039147 GO:0017136|NAD-dependent histone deacetylase activity, ! spindle checkpoint GO:0031577 7 7 0,000 0,01079547 0,03910813 ! apolipoprotein binding GO:0034185 9 7 0,000 0,01079547 0,03906933 ! G1 DNA damage checkpoint GO:0031571 7 7 0,000 0,01079547 0,03903061 ! segment specification GO:0007379 9 7 0,000 0,01079547 0,03899196 ! pronucleus GO:0045120 25 7 0,000 0,01079547 0,0389534 ! bile acid:sodium symporter activity GO:0008508 9 7 0,000 0,01079547 0,0389149 ! Rac GTPase activator activity GO:0030675 9 7 0,000 0,01079547 0,03887649 ! regulation of DNA repair GO:0006282 19 7 0,000 0,01079547 0,03883815 ! preribosome GO:0030684 7 7 0,000 0,01079547 0,03879988 ! DNA topological change GO:0006265 7 7 0,000 0,01079547 0,0387617 ! DNA ligation GO:0006266 8 7 0,000 0,01079547 0,03872358 ! hair follicle maturation GO:0048820 8 7 0,000 0,01079547 0,03868554 ! renal water homeostasis GO:0003091 7 7 0,000 0,01079547 0,03864758 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 0,01079547 0,03860969 ! positive regulation of interleukin-6 production GO:0032755 7 7 0,000 0,01079547 0,03857187 ! interleukin-1 receptor activity GO:0004908 8 7 0,000 0,01079547 0,03853413 ! positive regulation of tumor necrosis factor production GO:0032760 7 7 0,000 0,01079547 0,03849646 ! positive regulation of monooxygenase activity GO:0032770 7 7 0,000 0,01079547 0,03845887 ! inositol trisphosphate 3-kinase activity GO:0008440 8 7 0,000 0,01079547 0,03842135 ! phosphofructokinase activity GO:0008443 7 7 0,000 0,01079547 0,0383839 ! gap junction channel activity GO:0005243 8 7 0,000 0,01079547 0,03834653 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 10 7 0,000 0,01079547 0,03830922 ! histone methylation GO:0016571 7 7 0,000 0,01079547 0,03827199 ! positive regulation of interferon-gamma production GO:0032729 7 7 0,000 0,01079547 0,03823484 ! negative regulation of tumor necrosis factor production GO:0032720 9 7 0,000 0,01079547 0,03819775 ! mitochondrion morphogenesis GO:0070584 9 7 0,000 0,01079547 0,03816074 ! muscle cell proliferation GO:0033002 8 7 0,000 0,01079547 0,0381238 ! transcription termination GO:0006353 9 7 0,000 0,01079547 0,03808693 ! regulation of transcription from RNA polymerase III promoter GO:0006359 16 7 0,000 0,01079547 0,03805013 ! sodium:amino acid symporter activity GO:0005283 7 7 0,000 0,01079547 0,0380134 ! cytidylyltransferase activity GO:0070567 8 7 0,000 0,01079547 0,03797674 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 0,01079547 0,03794016 ! ATP-dependent peptidase activity GO:0004176 7 7 0,000 0,01079547 0,03790364 ! salivary gland development GO:0007431 7 7 0,000 0,01079547 0,0378672 ! glucosidase activity GO:0015926 8 7 0,000 0,01079547 0,03783082 ! NuRD complex GO:0016581 8 7 0,000 0,01079547 0,03779451 ! negative regulation of nuclear division GO:0051784 7 7 0,000 0,01079547 0,03775828 GO:0045839|negative regulation of mitosis, ! ATP-gated cation channel activity GO:0004931 9 7 0,000 0,01079547 0,03772211 ! response to redox state GO:0051775 8 7 0,000 0,01079547 0,03768601 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 0,01079547 0,03764998 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01079547 0,03761402 ! procollagen-proline dioxygenase activity GO:0019798 7 7 0,000 0,01079547 0,03757813 ! actin monomer binding GO:0003785 7 7 0,000 0,01079547 0,03754231 ! protein prenyltransferase activity GO:0008318 8 7 0,000 0,01079547 0,03750656 ! endosome to lysosome transport GO:0008333 7 7 0,000 0,01079547 0,03747087 ! regulation of Rac protein signal transduction GO:0035020 17 7 0,000 0,01079547 0,03743525 ! germ cell migration GO:0008354 7 7 0,000 0,01079547 0,0373997 ! fibroblast growth factor receptor binding GO:0005104 8 7 0,000 0,01079547 0,03736422 ! negative regulation of organic acid transport GO:0032891 8 7 0,000 0,01079547 0,0373288 ! CoA-ligase activity GO:0016405 8 7 0,000 0,01079547 0,03729345 ! positive regulation of NF-kappaB import into nucleus GO:0042346 8 7 0,000 0,01079547 0,03725817 ! interferon-alpha/beta receptor binding GO:0005132 7 7 0,000 0,01079547 0,03722295 ! embryonic heart tube development GO:0035050 8 7 0,000 0,01079547 0,0371878 ! dihydropyridine-sensitive calcium channel activity GO:0015270 10 7 0,000 0,01079547 0,03715272 ! kainate selective glutamate receptor activity GO:0015277 8 7 0,000 0,01079547 0,0371177 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 0,01079547 0,03708275 ! amiloride-sensitive sodium channel activity GO:0015280 7 7 0,000 0,01079547 0,03704787 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01079547 0,03701305 ! adenylate kinase activity GO:0004017 8 7 0,000 0,01079547 0,03697829 ! negative regulation of immune effector process GO:0002698 13 7 0,000 0,01079547 0,0369436 ! C-X-C chemokine receptor activity GO:0016494 7 7 0,000 0,01079547 0,03690898 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 7 7 0,000 0,01079547 0,03687442 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 10 8 0,000 0,01232847 0,04207133 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 9 8 0,000 0,01232847 0,04203201 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 8 0,000 0,01232847 0,04199276 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 0,01232847 0,04195359 ! negative regulation of lipid biosynthetic process GO:0051055 18 8 0,000 0,01232847 0,04191449 ! regulation of cellular amine metabolic process GO:0033238 10 8 0,000 0,01232847 0,04187546 ! proteasome regulatory particle GO:0005838 8 8 0,000 0,01232847 0,04183651 ! SMAD protein complex assembly GO:0007183 10 8 0,000 0,01232847 0,04179763 ! regulation of smooth muscle cell migration GO:0014910 11 8 0,000 0,01232847 0,04175882 ! protein self-association GO:0043621 8 8 0,000 0,01232847 0,04172008 ! glycine hydroxymethyltransferase activity GO:0004372 9 8 0,000 0,01232847 0,04168142 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 8 0,000 0,01232847 0,04164282 ! neurotransmitter uptake GO:0001504 8 8 0,000 0,01232847 0,0416043 ! regulation of activated T cell proliferation GO:0046006 9 8 0,000 0,01232847 0,04156585 ! guanylate cyclase activity GO:0004383 9 8 0,000 0,01232847 0,04152747 ! troponin complex GO:0005861 8 8 0,000 0,01232847 0,04148916 ! eukaryotic translation initiation factor 3 complex GO:0005852 8 8 0,000 0,01232847 0,04145092 ! tachykinin receptor signaling pathway GO:0007217 8 8 0,000 0,01232847 0,04141275 ! keratinocyte proliferation GO:0043616 9 8 0,000 0,01232847 0,04137465 ! negative regulation of muscle cell differentiation GO:0051148 10 8 0,000 0,01232847 0,04133662 ! microtubule bundle formation GO:0001578 8 8 0,000 0,01232847 0,04129867 ! middle ear morphogenesis GO:0042474 10 8 0,000 0,01232847 0,04126078 ! ganglioside metabolic process GO:0001573 8 8 0,000 0,01232847 0,04122296 ! regulation of mesenchymal cell proliferation GO:0010464 9 8 0,000 0,01232847 0,04118521 GO:0002053|positive regulation of mesenchymal cell proliferation, ! ovulation from ovarian follicle GO:0001542 8 8 0,000 0,01232847 0,04114753 ! ciliary or flagellar motility GO:0001539 8 8 0,000 0,01232847 0,04110992 ! pathogenesis GO:0009405 8 8 0,000 0,01232847 0,04107237 ! pH reduction GO:0045851 9 8 0,000 0,01232847 0,0410349 ! small protein activating enzyme activity GO:0008641 10 8 0,000 0,01232847 0,04099749 ! ribonucleoside triphosphate catabolic process GO:0009203 8 8 0,000 0,01232847 0,04096015 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 0,01232847 0,04092288 ! hemoglobin metabolic process GO:0020027 8 8 0,000 0,01232847 0,04088568 ! regulation of S phase of mitotic cell cycle GO:0007090 8 8 0,000 0,01232847 0,04084854 ! arginine catabolic process GO:0006527 9 8 0,000 0,01232847 0,04081148 ! T-tubule GO:0030315 9 8 0,000 0,01232847 0,04077448 ! regulation of defense response to virus by virus GO:0050690 17 8 0,000 0,01232847 0,04073754 ! histidine catabolic process GO:0006548 8 8 0,000 0,01232847 0,04070068 GO:0009077|histidine family amino acid catabolic process, ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 0,01232847 0,04066388 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 8 0,000 0,01232847 0,04062714 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 10 8 0,000 0,01232847 0,04059048 ! proline metabolic process GO:0006560 10 8 0,000 0,01232847 0,04055388 ! L-serine metabolic process GO:0006563 9 8 0,000 0,01232847 0,04051734 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 8 8 0,000 0,01232847 0,04048087 ! melanosome membrane GO:0033162 9 8 0,000 0,01232847 0,04044447 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,01232847 0,04040813 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 8 8 0,000 0,01232847 0,04037186 ! pericentriolar material GO:0000242 9 8 0,000 0,01232847 0,04033565 ! reverse cholesterol transport GO:0043691 8 8 0,000 0,01232847 0,04029951 ! tumor necrosis factor receptor activity GO:0005031 8 8 0,000 0,01232847 0,04026343 ! melanin metabolic process GO:0006582 10 8 0,000 0,01232847 0,04022741 ! proton-transporting V-type ATPase, V1 domain GO:0033180 8 8 0,000 0,01232847 0,04019146 ! phasic smooth muscle contraction GO:0014821 9 8 0,000 0,01232847 0,04015558 ! Golgi lumen GO:0005796 8 8 0,000 0,01232847 0,04011976 ! positive regulation of endothelial cell migration GO:0010595 9 8 0,000 0,01232847 0,040084 ! regulation of Cdc42 protein signal transduction GO:0032489 9 8 0,000 0,01232847 0,04004831 GO:0043088|regulation of Cdc42 GTPase activity, ! methyltransferase complex GO:0034708 8 8 0,000 0,01232847 0,04001268 GO:0035097|histone methyltransferase complex, ! paraxial mesoderm development GO:0048339 10 8 0,000 0,01232847 0,03997711 ! stereocilium bundle GO:0032421 11 8 0,000 0,01232847 0,03994161 ! forebrain cell migration GO:0021885 9 8 0,000 0,01232847 0,03990616 ! peptidyl-threonine phosphorylation GO:0018107 11 8 0,000 0,01232847 0,03987079 ! osteoblast development GO:0002076 11 8 0,000 0,01232847 0,03983547 ! retinoic acid metabolic process GO:0042573 8 8 0,000 0,01232847 0,03980022 ! retinol metabolic process GO:0042572 8 8 0,000 0,01232847 0,03976503 ! negative regulation of muscle contraction GO:0045932 10 8 0,000 0,01232847 0,0397299 ! structural constituent of epidermis GO:0030280 9 8 0,000 0,01232847 0,03969483 ! clathrin binding GO:0030276 10 8 0,000 0,01232847 0,03965983 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 9 8 0,000 0,01232847 0,03962489 ! chondroitin sulfate biosynthetic process GO:0030206 9 8 0,000 0,01232847 0,03959001 GO:0030204|chondroitin sulfate metabolic process, ! sodium:dicarboxylate symporter activity GO:0017153 9 8 0,000 0,01232847 0,03955519 ! motor axon guidance GO:0008045 8 8 0,000 0,01232847 0,03952043 ! protein targeting to vacuole GO:0006623 8 8 0,000 0,01232847 0,03948573 ! negative regulation of axonogenesis GO:0050771 12 8 0,000 0,01232847 0,03945109 ! peptidyl-asparagine modification GO:0018196 8 8 0,000 0,01232847 0,03941652 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! melanosome localization GO:0032400 8 8 0,000 0,01232847 0,039382 GO:0032401|establishment of melanosome localization, GO:0051875|pigment granule localization, GO:0051905|establishment of pigment granule localization, ! mismatch repair complex binding GO:0032404 10 8 0,000 0,01232847 0,03934755 ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 0,01232847 0,03931315 ! protein-lipid complex assembly GO:0065005 8 8 0,000 0,01232847 0,03927882 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 9 8 0,000 0,01232847 0,03924454 ! phosphoinositide 3-kinase cascade GO:0014065 8 8 0,000 0,01232847 0,03921033 ! regulation of dopamine secretion GO:0014059 9 8 0,000 0,01232847 0,03917617 ! regulation of protein kinase B signaling cascade GO:0051896 9 8 0,000 0,01232847 0,03914208 ! cranial nerve morphogenesis GO:0021602 9 8 0,000 0,01232847 0,03910804 ! subpallium development GO:0021544 8 8 0,000 0,01232847 0,03907406 ! positive regulation of Rho GTPase activity GO:0032321 11 8 0,000 0,01232847 0,03904015 ! icosanoid secretion GO:0032309 10 8 0,000 0,01232847 0,03900629 GO:0050482|arachidonic acid secretion, ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 0,01232847 0,03897249 ! regulation of DNA replication initiation GO:0030174 8 8 0,000 0,01232847 0,03893874 ! negative regulation of cytokine secretion GO:0050710 10 8 0,000 0,01232847 0,03890506 ! dolichyl-diphosphooligosaccharide-protein glycotransferase activity GO:0004579 8 8 0,000 0,01232847 0,03887143 ! exodeoxyribonuclease activity GO:0004529 18 8 0,000 0,01232847 0,03883787 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! ER to Golgi transport vesicle GO:0030134 9 8 0,000 0,01232847 0,03880436 ! nucleotide diphosphatase activity GO:0004551 9 8 0,000 0,01232847 0,0387709 ! regulation of myoblast differentiation GO:0045661 9 8 0,000 0,01232847 0,03873751 ! ubiquinone metabolic process GO:0006743 9 8 0,000 0,01232847 0,03870417 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! neuromuscular process controlling posture GO:0050884 8 8 0,000 0,01232847 0,03867089 ! multicellular organismal water homeostasis GO:0050891 8 8 0,000 0,01232847 0,03863767 ! branched chain family amino acid catabolic process GO:0009083 9 8 0,000 0,01232847 0,0386045 ! Wnt receptor activity GO:0042813 11 8 0,000 0,01232847 0,0385714 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 0,01232847 0,03853834 ! leukocyte mediated cytotoxicity GO:0001909 10 8 0,000 0,01232847 0,03850535 ! detection of calcium ion GO:0005513 9 8 0,000 0,01232847 0,03847241 ! negative regulation of glucose import GO:0046325 9 8 0,000 0,01232847 0,03843953 ! blastocyst growth GO:0001832 8 8 0,000 0,01232847 0,0384067 ! regulation of fibrinolysis GO:0051917 8 8 0,000 0,01232847 0,03837393 ! negative regulation of telomere maintenance GO:0032205 9 8 0,000 0,01232847 0,03834122 ! cerebellar cortex formation GO:0021697 9 8 0,000 0,01232847 0,03830856 ! complement binding GO:0001848 11 8 0,000 0,01232847 0,03827596 ! regulation of actin filament bundle formation GO:0032231 13 8 0,000 0,01232847 0,03824341 GO:0051492|regulation of stress fiber formation, ! regulation of synaptic transmission, dopaminergic GO:0032225 10 8 0,000 0,01232847 0,03821092 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 8 0,000 0,01232847 0,03817848 ! amino sugar catabolic process GO:0046348 8 8 0,000 0,01232847 0,0381461 GO:0006043|glucosamine catabolic process, ! FK506 binding GO:0005528 9 8 0,000 0,01232847 0,03811377 GO:0005527|macrolide binding, ! dipeptidase activity GO:0016805 8 8 0,000 0,01232847 0,0380815 ! positive regulation of amine transport GO:0051954 9 8 0,000 0,01232847 0,03804928 ! release of sequestered calcium ion into cytosol GO:0051209 13 8 0,000 0,01232847 0,03801712 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, ! B cell receptor signaling pathway GO:0050853 13 8 0,000 0,01232847 0,03798501 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01232847 0,03795295 ! Golgi transport complex GO:0017119 8 8 0,000 0,01232847 0,03792095 ! positive regulation of protein ubiquitination GO:0031398 17 8 0,000 0,01232847 0,037889 ! GDP binding GO:0019003 9 8 0,000 0,01232847 0,03785711 ! positive regulation of glucose metabolic process GO:0010907 8 8 0,000 0,01232847 0,03782527 ! prostate gland development GO:0030850 17 8 0,000 0,01232847 0,03779349 ! DNA synthesis during DNA repair GO:0000731 19 8 0,000 0,01232847 0,03776175 ! nitric-oxide synthase binding GO:0050998 9 8 0,000 0,01232847 0,03773007 ! phosphate transport GO:0006817 9 8 0,000 0,01232847 0,03769845 ! cellular copper ion homeostasis GO:0006878 8 8 0,000 0,01232847 0,03766687 ! oligopeptide transport GO:0006857 8 8 0,000 0,01232847 0,03763535 GO:0015198|oligopeptide transporter activity, ! pigment cell differentiation GO:0050931 9 8 0,000 0,01232847 0,03760389 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 0,01232847 0,03757247 ! oligosaccharyltransferase complex GO:0008250 8 8 0,000 0,01232847 0,03754111 ! lipoprotein transport GO:0042953 9 8 0,000 0,01232847 0,0375098 ! estrogen metabolic process GO:0008210 8 8 0,000 0,01232847 0,03747854 ! nucleocytoplasmic transporter activity GO:0005487 8 8 0,000 0,01232847 0,03744733 ! glucocorticoid metabolic process GO:0008211 8 8 0,000 0,01232847 0,03741618 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 8 8 0,000 0,01232847 0,03738508 ! T-helper 1 type immune response GO:0042088 8 8 0,000 0,01232847 0,03735403 ! amyloid precursor protein catabolic process GO:0042987 10 8 0,000 0,01232847 0,03732303 ! response to amphetamine GO:0001975 11 8 0,000 0,01232847 0,03729208 ! mechanosensory behavior GO:0007638 8 8 0,000 0,01232847 0,03726118 ! detection of chemical stimulus involved in sensory perception GO:0050907 8 8 0,000 0,01232847 0,03723034 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 0,01232847 0,03719954 ! C-X-C chemokine binding GO:0019958 8 8 0,000 0,01232847 0,0371688 ! two-component signal transduction system (phosphorelay) GO:0000160 9 8 0,000 0,01232847 0,03713811 ! glycerolipid catabolic process GO:0046503 17 8 0,000 0,01232847 0,03710747 ! spinal cord dorsal/ventral patterning GO:0021513 10 8 0,000 0,01232847 0,03707687 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 9 8 0,000 0,01232847 0,03704633 ! inositol phosphate-mediated signaling GO:0048016 9 8 0,000 0,01232847 0,03701584 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 0,01232847 0,0369854 ! pigment granule organization GO:0048753 9 8 0,000 0,01232847 0,03695501 ! GTP-dependent protein binding GO:0030742 11 8 0,000 0,01232847 0,03692467 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 0,01232847 0,03689438 ! regulation of interleukin-8 biosynthetic process GO:0045414 9 8 0,000 0,01232847 0,03686414 ! regulation of pigmentation during development GO:0048070 11 8 0,000 0,01232847 0,03683395 ! macrophage activation GO:0042116 8 8 0,000 0,01232847 0,0368038 ! poly(A) RNA binding GO:0008143 8 8 0,000 0,01232847 0,03677371 ! positive regulation of insulin secretion GO:0032024 10 8 0,000 0,01232847 0,03674367 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 18 8 0,000 0,01232847 0,03671367 ! asymmetric protein localization GO:0008105 9 8 0,000 0,01232847 0,03668373 ! nucleotide-sugar transmembrane transporter activity GO:0005338 8 8 0,000 0,01232847 0,03665383 ! neurotrophin binding GO:0043121 10 8 0,000 0,01232847 0,03662398 ! nucleoside transmembrane transporter activity GO:0005337 9 8 0,000 0,01232847 0,03659418 ! positive regulation of multicellular organismal metabolic process GO:0044253 9 8 0,000 0,01232847 0,03656443 ! phagocytosis, engulfment GO:0006911 10 8 0,000 0,01232847 0,03653473 ! UDP-glucosyltransferase activity GO:0035251 8 8 0,000 0,01232847 0,03650507 ! neurotransmitter biosynthetic process GO:0042136 9 8 0,000 0,01232847 0,03647546 ! UV protection GO:0009650 9 8 0,000 0,01232847 0,03644591 ! peptidyl-proline dioxygenase activity GO:0031543 8 8 0,000 0,01232847 0,03641639 ! eukaryotic translation initiation factor 4F complex GO:0016281 10 8 0,000 0,01232847 0,03638693 ! glutathione peroxidase activity GO:0004602 17 8 0,000 0,01232847 0,03635752 ! acyl-CoA thioesterase activity GO:0016291 10 8 0,000 0,01232847 0,03632815 ! ATP-binding cassette (ABC) transporter complex GO:0043190 8 8 0,000 0,01232847 0,03629883 ! ferric iron binding GO:0008199 9 8 0,000 0,01232847 0,03626955 ! response to UV-B GO:0010224 10 8 0,000 0,01232847 0,03624033 ! intermediate filament organization GO:0045109 8 8 0,000 0,01232847 0,03621115 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 0,01232847 0,03618202 ! cellular extravasation GO:0045123 9 8 0,000 0,01232847 0,03615293 ! skeletal muscle contraction GO:0003009 8 8 0,000 0,01232847 0,03612389 ! positive regulation of cytokine production during immune response GO:0002720 8 8 0,000 0,01232847 0,0360949 ! regulation of fatty acid biosynthetic process GO:0042304 17 8 0,000 0,01232847 0,03606596 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,01232847 0,03603706 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 0,01232847 0,0360082 ! positive regulation of systemic arterial blood pressure GO:0003084 10 8 0,000 0,01232847 0,0359794 ! negative regulation of systemic arterial blood pressure GO:0003085 9 8 0,000 0,01232847 0,03595064 ! respiratory chain complex IV assembly GO:0008535 8 8 0,000 0,01232847 0,03592192 ! erythrocyte development GO:0048821 9 8 0,000 0,01232847 0,03589325 ! regulation of interleukin-10 production GO:0032653 8 8 0,000 0,01232847 0,03586463 ! ribosome assembly GO:0042255 8 8 0,000 0,01232847 0,03583605 ! postreplication repair GO:0006301 19 8 0,000 0,01232847 0,03580752 ! gamma-tubulin binding GO:0043015 8 8 0,000 0,01232847 0,03577904 ! NADPH oxidase complex GO:0043020 8 8 0,000 0,01232847 0,03575059 ! mRNA cleavage GO:0006379 9 8 0,000 0,01232847 0,0357222 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 9 8 0,000 0,01232847 0,03569385 ! opioid receptor activity GO:0004985 8 8 0,000 0,01232847 0,03566554 ! zymogen activation GO:0031638 9 8 0,000 0,01232847 0,03563728 ! coenzyme A metabolic process GO:0015936 8 8 0,000 0,01232847 0,03560906 ! cellular metabolic compound salvage GO:0043094 11 8 0,000 0,01232847 0,03558089 ! costamere GO:0043034 8 8 0,000 0,01232847 0,03555277 ! inositol trisphosphate kinase activity GO:0051766 9 8 0,000 0,01232847 0,03552468 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 0,01232847 0,03549664 ! sarcomere organization GO:0045214 9 8 0,000 0,01232847 0,03546865 ! wide pore channel activity GO:0022829 9 8 0,000 0,01232847 0,0354407 ! ligand-regulated transcription factor activity GO:0003706 10 8 0,000 0,01232847 0,03541279 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 0,01232847 0,03538493 ! hormone catabolic process GO:0042447 9 8 0,000 0,01232847 0,03535711 ! mRNA 3'-UTR binding GO:0003730 9 8 0,000 0,01232847 0,03532934 ! cGMP biosynthetic process GO:0006182 9 8 0,000 0,01232847 0,03530161 ! lysozyme activity GO:0003796 10 8 0,000 0,01232847 0,03527392 ! death receptor binding GO:0005123 8 8 0,000 0,01232847 0,03524628 ! protein modification by small protein removal GO:0070646 9 8 0,000 0,01232847 0,03521867 ! adult feeding behavior GO:0008343 9 8 0,000 0,01232847 0,03519112 ! microtubule basal body GO:0005932 8 8 0,000 0,01232847 0,0351636 ! pyrimidine nucleotide catabolic process GO:0006244 8 8 0,000 0,01232847 0,03513613 ! interleukin-1 receptor binding GO:0005149 9 8 0,000 0,01232847 0,0351087 ! calcium-release channel activity GO:0015278 8 8 0,000 0,01232847 0,03508132 ! positive regulation of smooth muscle contraction GO:0045987 9 8 0,000 0,01232847 0,03505397 ! behavioral response to nicotine GO:0035095 9 8 0,000 0,01232847 0,03502667 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 0,01232847 0,03499941 ! adenosine deaminase activity GO:0004000 8 8 0,000 0,01232847 0,0349722 ! NAD biosynthetic process GO:0009435 9 8 0,000 0,01232847 0,03494503 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 9 0,000 0,01385917 0,0392533 ! positive regulation of glycogen biosynthetic process GO:0045725 9 9 0,000 0,01385917 0,03922284 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 0,01385917 0,03919244 ! sodium:hydrogen antiporter activity GO:0015385 9 9 0,000 0,01385917 0,03916208 GO:0005451|monovalent cation:hydrogen antiporter activity, ! cGMP metabolic process GO:0046068 10 9 0,000 0,01385917 0,03913177 ! myotube differentiation GO:0014902 9 9 0,000 0,01385917 0,0391015 ! folic acid and derivative biosynthetic process GO:0009396 9 9 0,000 0,01385917 0,03907129 ! N-glycan processing GO:0006491 10 9 0,000 0,01385917 0,03904112 ! regulation of epidermal growth factor receptor activity GO:0007176 11 9 0,000 0,01385917 0,03901099 ! actin-myosin filament sliding GO:0033275 11 9 0,000 0,01385917 0,03898091 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! axon part GO:0033267 12 9 0,000 0,01385917 0,03895088 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 10 9 0,000 0,01385917 0,0389209 ! RNA methylation GO:0001510 9 9 0,000 0,01385917 0,03889096 ! prostaglandin biosynthetic process GO:0001516 9 9 0,000 0,01385917 0,03886106 GO:0046457|prostanoid biosynthetic process, ! negative regulation of gene-specific transcription GO:0032582 10 9 0,000 0,01385917 0,03883122 ! artery development GO:0060840 9 9 0,000 0,01385917 0,03880142 GO:0048844|artery morphogenesis, ! axonemal dynein complex GO:0005858 9 9 0,000 0,01385917 0,03877166 ! regulation of postsynaptic membrane potential GO:0060078 11 9 0,000 0,01385917 0,03874195 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 9 9 0,000 0,01385917 0,03871229 ! auditory receptor cell differentiation GO:0042491 10 9 0,000 0,01385917 0,03868267 ! positive regulation of heart contraction GO:0045823 11 9 0,000 0,01385917 0,03865309 ! lipopolysaccharide binding GO:0001530 9 9 0,000 0,01385917 0,03862356 ! regulated secretory pathway GO:0045055 10 9 0,000 0,01385917 0,03859408 ! estrogen receptor binding GO:0030331 9 9 0,000 0,01385917 0,03856464 ! inner mitochondrial membrane organization GO:0007007 10 9 0,000 0,01385917 0,03853525 ! telomere maintenance via telomerase GO:0007004 20 9 0,000 0,01385917 0,0385059 GO:0006278|RNA-dependent DNA replication, ! L-phenylalanine metabolic process GO:0006558 9 9 0,000 0,01385917 0,03847659 GO:0006559|L-phenylalanine catabolic process, ! indolalkylamine metabolic process GO:0006586 9 9 0,000 0,01385917 0,03844733 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 9 9 0,000 0,01385917 0,03841812 ! urea metabolic process GO:0019627 19 9 0,000 0,01385917 0,03838895 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! smooth endoplasmic reticulum GO:0005790 11 9 0,000 0,01385917 0,03835982 ! autophagic vacuole GO:0005776 11 9 0,000 0,01385917 0,03833074 ! Rac GTPase binding GO:0048365 10 9 0,000 0,01385917 0,0383017 ! response to dietary excess GO:0002021 9 9 0,000 0,01385917 0,03827271 ! regulation of sodium ion transport GO:0002028 10 9 0,000 0,01385917 0,03824376 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 0,01385917 0,03821485 ! lens development in camera-type eye GO:0002088 9 9 0,000 0,01385917 0,03818599 ! male sex determination GO:0030238 9 9 0,000 0,01385917 0,03815717 ! positive regulation of vasodilation GO:0045909 19 9 0,000 0,01385917 0,03812839 ! positive regulation of muscle contraction GO:0045933 11 9 0,000 0,01385917 0,03809966 ! regulation of smoothened signaling pathway GO:0008589 11 9 0,000 0,01385917 0,03807097 ! male germ cell nucleus GO:0001673 11 9 0,000 0,01385917 0,03804232 ! negative regulation of foam cell differentiation GO:0010745 12 9 0,000 0,01385917 0,03801372 ! copper ion homeostasis GO:0055070 9 9 0,000 0,01385917 0,03798516 ! protein heterooligomerization GO:0051291 10 9 0,000 0,01385917 0,03795664 ! spectrin GO:0008091 9 9 0,000 0,01385917 0,03792817 ! cardiac muscle cell differentiation GO:0055007 12 9 0,000 0,01385917 0,03789973 ! purine nucleoside triphosphate catabolic process GO:0009146 9 9 0,000 0,01385917 0,03787134 ! synaptic vesicle exocytosis GO:0016079 10 9 0,000 0,01385917 0,037843 ! regulation of B cell differentiation GO:0045577 10 9 0,000 0,01385917 0,03781469 ! cell differentiation in hindbrain GO:0021533 10 9 0,000 0,01385917 0,03778643 ! neural tube patterning GO:0021532 10 9 0,000 0,01385917 0,03775821 ! fucose catabolic process GO:0019317 10 9 0,000 0,01385917 0,03773003 GO:0042355|L-fucose catabolic process, ! retinal ganglion cell axon guidance GO:0031290 10 9 0,000 0,01385917 0,0377019 ! regulation of hormone metabolic process GO:0032350 12 9 0,000 0,01385917 0,0376738 ! sterol catabolic process GO:0016127 10 9 0,000 0,01385917 0,03764575 GO:0006707|cholesterol catabolic process, ! oligosaccharyl transferase activity GO:0004576 9 9 0,000 0,01385917 0,03761774 ! clathrin coat of coated pit GO:0030132 11 9 0,000 0,01385917 0,03758977 ! SNARE complex GO:0031201 11 9 0,000 0,01385917 0,03756185 ! negative regulation of osteoclast differentiation GO:0045671 10 9 0,000 0,01385917 0,03753396 ! negative regulation of glucose transport GO:0010829 10 9 0,000 0,01385917 0,03750612 ! methionine biosynthetic process GO:0009086 11 9 0,000 0,01385917 0,03747831 ! peptidoglycan binding GO:0042834 9 9 0,000 0,01385917 0,03745055 ! serine family amino acid biosynthetic process GO:0009070 10 9 0,000 0,01385917 0,03742283 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 0,01385917 0,03739515 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! nicotinamide nucleotide biosynthetic process GO:0019359 10 9 0,000 0,01385917 0,03736751 ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 9 9 0,000 0,01385917 0,03733991 GO:0003756|protein disulfide isomerase activity, ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 0,01385917 0,03731236 ! beta-1,3-galactosyltransferase activity GO:0048531 10 9 0,000 0,01385917 0,03728484 ! detection of bacterium GO:0016045 10 9 0,000 0,01385917 0,03725737 ! lymphocyte activation during immune response GO:0002285 9 9 0,000 0,01385917 0,03722993 ! embryonic gut development GO:0048566 10 9 0,000 0,01385917 0,03720253 ! hydrolase activity, acting on ether bonds GO:0016801 10 9 0,000 0,01385917 0,03717518 ! desmosome GO:0030057 10 9 0,000 0,01385917 0,03714787 ! long-chain-fatty-acid-CoA ligase activity GO:0004467 9 9 0,000 0,01385917 0,03712059 ! T cell receptor signaling pathway GO:0050852 14 9 0,000 0,01385917 0,03709336 ! positive regulation of calcium-mediated signaling GO:0050850 11 9 0,000 0,01385917 0,03706616 ! actin filament polymerization GO:0030041 10 9 0,000 0,01385917 0,03703901 ! negative regulation of B cell activation GO:0050869 10 9 0,000 0,01385917 0,03701189 ! regulation of synapse organization GO:0050807 10 9 0,000 0,01385917 0,03698482 ! septin complex GO:0031105 10 9 0,000 0,01385917 0,03695778 GO:0032156|septin cytoskeleton, ! cholesterol transporter activity GO:0017127 9 9 0,000 0,01385917 0,03693078 ! anchoring collagen GO:0030934 9 9 0,000 0,01385917 0,03690383 ! defense response to Gram-negative bacterium GO:0050829 10 9 0,000 0,01385917 0,03687691 ! regulation of developmental growth GO:0048638 11 9 0,000 0,01385917 0,03685003 ! negative regulation of smooth muscle cell proliferation GO:0048662 10 9 0,000 0,01385917 0,03682319 ! GMP binding GO:0019002 11 9 0,000 0,01385917 0,03679639 GO:0030553|cGMP binding, ! photoreceptor activity GO:0009881 10 9 0,000 0,01385917 0,03676963 ! virus-host interaction GO:0019048 13 9 0,000 0,01385917 0,03674291 ! pentose-phosphate shunt GO:0006098 11 9 0,000 0,01385917 0,03671623 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 0,01385917 0,03668958 ! negative regulation of lipid catabolic process GO:0050995 11 9 0,000 0,01385917 0,03666298 ! non-recombinational repair GO:0000726 10 9 0,000 0,01385917 0,03663641 GO:0006303|double-strand break repair via nonhomologous end joining, ! cell volume homeostasis GO:0006884 10 9 0,000 0,01385917 0,03660988 ! nuclear telomere cap complex GO:0000783 10 9 0,000 0,01385917 0,03658339 GO:0000782|telomere cap complex, ! activin binding GO:0048185 10 9 0,000 0,01385917 0,03655694 ! social behavior GO:0035176 10 9 0,000 0,01385917 0,03653052 ! regulation of positive chemotaxis GO:0050926 11 9 0,000 0,01385917 0,03650415 GO:0050927|positive regulation of positive chemotaxis, ! perikaryon GO:0043204 11 9 0,000 0,01385917 0,03647781 ! nitric oxide biosynthetic process GO:0006809 10 9 0,000 0,01385917 0,03645151 ! mating GO:0007618 11 9 0,000 0,01385917 0,03642525 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 9 0,000 0,01385917 0,03639902 ! rhythmic behavior GO:0007622 11 9 0,000 0,01385917 0,03637284 ! phospholipid efflux GO:0033700 10 9 0,000 0,01385917 0,03634669 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 0,01385917 0,03632058 ! poly-purine tract binding GO:0070717 9 9 0,000 0,01385917 0,0362945 ! T cell proliferation GO:0042098 10 9 0,000 0,01385917 0,03626847 ! retinol dehydrogenase activity GO:0004745 9 9 0,000 0,01385917 0,03624247 ! negative regulation of cell-matrix adhesion GO:0001953 10 9 0,000 0,01385917 0,03621651 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 9 9 0,000 0,01385917 0,03619058 ! interleukin-1 binding GO:0019966 10 9 0,000 0,01385917 0,0361647 ! glucosyltransferase activity GO:0046527 9 9 0,000 0,01385917 0,03613885 ! platelet-derived growth factor receptor signaling pathway GO:0048008 14 9 0,000 0,01385917 0,03611303 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 11 9 0,000 0,01385917 0,03608726 ! ovulation GO:0030728 9 9 0,000 0,01385917 0,03606152 ! acid phosphatase activity GO:0003993 18 9 0,000 0,01385917 0,03603581 ! embryonic cranial skeleton morphogenesis GO:0048701 10 9 0,000 0,01385917 0,03601015 ! ER overload response GO:0006983 11 9 0,000 0,01385917 0,03598452 ! B cell proliferation GO:0042100 10 9 0,000 0,01385917 0,03595892 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 11 9 0,000 0,01385917 0,03593336 ! calcium-transporting ATPase activity GO:0005388 11 9 0,000 0,01385917 0,03590784 ! mannose metabolic process GO:0006013 13 9 0,000 0,01385917 0,03588236 ! lipid digestion GO:0044241 11 9 0,000 0,01385917 0,03585691 ! tumor necrosis factor binding GO:0043120 9 9 0,000 0,01385917 0,0358315 ! tRNA methyltransferase activity GO:0008175 9 9 0,000 0,01385917 0,03580612 ! regulation of bone resorption GO:0045124 10 9 0,000 0,01385917 0,03578078 ! brain morphogenesis GO:0048854 9 9 0,000 0,01385917 0,03575548 ! positive regulation of alpha-beta T cell differentiation GO:0046638 10 9 0,000 0,01385917 0,03573021 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 10 9 0,000 0,01385917 0,03570497 ! synaptic vesicle membrane GO:0030672 9 9 0,000 0,01385917 0,03567978 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 9 0,000 0,01385917 0,03565462 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9 9 0,000 0,01385917 0,03562949 ! kinesin binding GO:0019894 9 9 0,000 0,01385917 0,0356044 ! multicellular organismal aging GO:0010259 18 9 0,000 0,01385917 0,03557934 ! Ran GTPase binding GO:0008536 11 9 0,000 0,01385917 0,03555432 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 0,01385917 0,03552934 ! protein import into peroxisome matrix GO:0016558 9 9 0,000 0,01385917 0,03550439 ! mRNA polyadenylation GO:0006378 10 9 0,000 0,01385917 0,03547947 ! neuropeptide Y receptor activity GO:0004983 10 9 0,000 0,01385917 0,03545459 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 14 9 0,000 0,01385917 0,03542974 ! prostaglandin receptor activity GO:0004955 11 9 0,000 0,01385917 0,03540493 ! caspase inhibitor activity GO:0043027 9 9 0,000 0,01385917 0,03538016 ! adrenoceptor activity GO:0004935 12 9 0,000 0,01385917 0,03535542 ! regulation of isotype switching GO:0045191 9 9 0,000 0,01385917 0,03533071 ! positive regulation of leukocyte migration GO:0002687 10 9 0,000 0,01385917 0,03530604 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 10 9 0,000 0,01385917 0,0352814 ! positive regulation of ATPase activity GO:0032781 11 9 0,000 0,01385917 0,0352568 ! nonprotein amino acid metabolic process GO:0019794 19 9 0,000 0,01385917 0,03523223 ! ionotropic glutamate receptor complex GO:0008328 14 9 0,000 0,01385917 0,03520769 ! Notch binding GO:0005112 10 9 0,000 0,01385917 0,03518319 ! ATPase regulator activity GO:0060590 10 9 0,000 0,01385917 0,03515872 ! gamma-tubulin complex GO:0000930 19 9 0,000 0,01385917 0,03513429 ! pyrimidine base metabolic process GO:0006206 10 9 0,000 0,01385917 0,03510989 ! tubulin-tyrosine ligase activity GO:0004835 10 9 0,000 0,01385917 0,03508553 ! alcohol dehydrogenase (NAD) activity GO:0004022 10 9 0,000 0,01385917 0,0350612 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 12 10 0,000 0,01538758 0,03890082 ! oligosaccharide biosynthetic process GO:0009312 10 10 0,000 0,01538758 0,03887388 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 10 0,000 0,01538758 0,03884698 ! sleep GO:0030431 11 10 0,000 0,01538758 0,03882011 ! positive regulation of lipid biosynthetic process GO:0046889 10 10 0,000 0,01538758 0,03879329 ! lipid particle GO:0005811 10 10 0,000 0,01538758 0,0387665 ! filopodium assembly GO:0046847 14 10 0,000 0,01538758 0,03873974 ! UTP metabolic process GO:0046051 12 10 0,000 0,01538758 0,03871302 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 13 10 0,000 0,01538758 0,03868634 ! guanylate kinase activity GO:0004385 14 10 0,000 0,01538758 0,0386597 ! integral to mitochondrial membrane GO:0032592 10 10 0,000 0,01538758 0,03863309 ! COPI coating of Golgi vesicle GO:0048205 11 10 0,000 0,01538758 0,03860652 GO:0048200|Golgi transport vesicle coating, ! platelet alpha granule membrane GO:0031092 11 10 0,000 0,01538758 0,03857999 ! macromolecule transmembrane transporter activity GO:0022884 11 10 0,000 0,01538758 0,03855349 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 10 0,000 0,01538758 0,03852703 ! thyroid hormone receptor coactivator activity GO:0030375 11 10 0,000 0,01538758 0,03850061 GO:0010861|thyroid hormone receptor activator activity, ! regulation of receptor activity GO:0010469 12 10 0,000 0,01538758 0,03847422 ! lung alveolus development GO:0048286 11 10 0,000 0,01538758 0,03844787 ! regulation of chemokine biosynthetic process GO:0045073 11 10 0,000 0,01538758 0,03842155 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01538758 0,03839527 ! negative regulation of striated muscle development GO:0045843 11 10 0,000 0,01538758 0,03836903 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 0,01538758 0,03834282 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 11 10 0,000 0,01538758 0,03831665 ! regulation of mRNA processing GO:0050684 12 10 0,000 0,01538758 0,03829051 ! positive regulation of survival gene product expression GO:0045885 12 10 0,000 0,01538758 0,03826441 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 11 10 0,000 0,01538758 0,03823834 ! transforming growth factor beta binding GO:0050431 11 10 0,000 0,01538758 0,03821231 ! histidine metabolic process GO:0006547 10 10 0,000 0,01538758 0,03818632 GO:0009075|histidine family amino acid metabolic process, ! glucan biosynthetic process GO:0009250 10 10 0,000 0,01538758 0,03816036 GO:0005978|glycogen biosynthetic process, ! endosome organization GO:0007032 13 10 0,000 0,01538758 0,03813443 ! death receptor activity GO:0005035 11 10 0,000 0,01538758 0,03810854 ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 0,01538758 0,03808269 ! entry into host cell GO:0030260 11 10 0,000 0,01538758 0,03805687 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 10 10 0,000 0,01538758 0,03803109 ! filamentous actin GO:0031941 11 10 0,000 0,01538758 0,03800534 ! behavioral fear response GO:0001662 12 10 0,000 0,01538758 0,03797962 GO:0002209|behavioral defense response, ! bone mineralization GO:0030282 12 10 0,000 0,01538758 0,03795395 ! negative regulation of ossification GO:0030279 12 10 0,000 0,01538758 0,0379283 ! phosphatidylcholine biosynthetic process GO:0006656 11 10 0,000 0,01538758 0,03790269 ! macrophage differentiation GO:0030225 11 10 0,000 0,01538758 0,03787712 ! positive regulation of phagocytosis GO:0050766 11 10 0,000 0,01538758 0,03785157 ! recycling endosome membrane GO:0055038 11 10 0,000 0,01538758 0,03782607 ! regulation of fat cell differentiation GO:0045598 11 10 0,000 0,01538758 0,0378006 ! snRNA metabolic process GO:0016073 10 10 0,000 0,01538758 0,03777516 GO:0016180|snRNA processing, ! glycosphingolipid biosynthetic process GO:0006688 11 10 0,000 0,01538758 0,03774975 ! regulation of mitochondrial membrane potential GO:0051881 11 10 0,000 0,01538758 0,03772439 ! purine ribonucleotide catabolic process GO:0009154 10 10 0,000 0,01538758 0,03769905 ! positive regulation of Ras GTPase activity GO:0032320 14 10 0,000 0,01538758 0,03767375 ! immunoglobulin production during immune response GO:0002381 10 10 0,000 0,01538758 0,03764848 ! nitric oxide metabolic process GO:0046209 20 10 0,000 0,01538758 0,03762325 ! induction of an organ GO:0001759 12 10 0,000 0,01538758 0,03759805 ! response to estradiol stimulus GO:0032355 11 10 0,000 0,01538758 0,03757288 ! synaptic vesicle endocytosis GO:0048488 12 10 0,000 0,01538758 0,03754775 ! negative regulation of MAPKKK cascade GO:0043409 12 10 0,000 0,01538758 0,03752265 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 10 0,000 0,01538758 0,03749759 ! MHC class II receptor activity GO:0032395 14 10 0,000 0,01538758 0,03747255 ! peptidyl-lysine modification GO:0018205 11 10 0,000 0,01538758 0,03744756 ! ribonuclease P activity GO:0004526 10 10 0,000 0,01538758 0,03742259 ! COPI vesicle coat GO:0030126 12 10 0,000 0,01538758 0,03739766 GO:0030663|COPI coated vesicle membrane, ! telomere maintenance via telomere lengthening GO:0010833 21 10 0,000 0,01538758 0,03737276 ! vitamin transporter activity GO:0051183 12 10 0,000 0,01538758 0,03734789 ! snRNA binding GO:0017069 11 10 0,000 0,01538758 0,03732306 ! negative regulation of osteoblast differentiation GO:0045668 12 10 0,000 0,01538758 0,03729826 ! heparan sulfate sulfotransferase activity GO:0034483 10 10 0,000 0,01538758 0,0372735 ! fatty-acid ligase activity GO:0015645 10 10 0,000 0,01538758 0,03724876 ! intramolecular transferase activity, phosphotransferases GO:0016868 11 10 0,000 0,01538758 0,03722406 ! quaternary ammonium group transport GO:0015697 10 10 0,000 0,01538758 0,03719939 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 10 10 0,000 0,01538758 0,03717476 ! metalloenzyme inhibitor activity GO:0048551 11 10 0,000 0,01538758 0,03715016 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! anterior/posterior axis specification GO:0009948 14 10 0,000 0,01538758 0,03712559 ! regulation of RNA splicing GO:0043484 13 10 0,000 0,01538758 0,03710105 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 10 10 0,000 0,01538758 0,03707654 ! trophectodermal cell differentiation GO:0001829 11 10 0,000 0,01538758 0,03705207 ! positive regulation of neuron apoptosis GO:0043525 11 10 0,000 0,01538758 0,03702763 ! extracellular matrix binding GO:0050840 11 10 0,000 0,01538758 0,03700322 ! regulation of synapse structure and activity GO:0050803 11 10 0,000 0,01538758 0,03697884 ! autophagic vacuole formation GO:0000045 11 10 0,000 0,01538758 0,0369545 ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 0,01538758 0,03693019 ! negative regulation of cell projection organization GO:0031345 14 10 0,000 0,01538758 0,03690591 ! negative regulation of cellular catabolic process GO:0031330 11 10 0,000 0,01538758 0,03688166 ! rough endoplasmic reticulum membrane GO:0030867 10 10 0,000 0,01538758 0,03685744 ! thyroid gland development GO:0030878 12 10 0,000 0,01538758 0,03683326 ! DNA bending activity GO:0008301 11 10 0,000 0,01538758 0,0368091 ! regulation of phosphatase activity GO:0010921 10 10 0,000 0,01538758 0,03678498 ! neutral lipid biosynthetic process GO:0046460 10 10 0,000 0,01538758 0,03676089 GO:0046463|acylglycerol biosynthetic process, ! embryonic hindlimb morphogenesis GO:0035116 11 10 0,000 0,01538758 0,03673684 ! embryonic forelimb morphogenesis GO:0035115 12 10 0,000 0,01538758 0,03671281 ! regulation of glucan biosynthetic process GO:0010962 10 10 0,000 0,01538758 0,03668881 GO:0005979|regulation of glycogen biosynthetic process, GO:0032885|regulation of polysaccharide biosynthetic process, ! secondary active sulfate transmembrane transporter activity GO:0008271 11 10 0,000 0,01538758 0,03666485 ! regulation of glycolysis GO:0006110 11 10 0,000 0,01538758 0,03664092 ! nucleotidase activity GO:0008252 10 10 0,000 0,01538758 0,03661702 ! phosphatidylinositol phosphate kinase activity GO:0016307 11 10 0,000 0,01538758 0,03659315 ! dipeptidyl-peptidase activity GO:0008239 12 10 0,000 0,01538758 0,03656931 ! androgen metabolic process GO:0008209 11 10 0,000 0,01538758 0,0365455 ! lateral plasma membrane GO:0016328 13 10 0,000 0,01538758 0,03652172 ! MAP kinase kinase activity GO:0004708 12 10 0,000 0,01538758 0,03649797 ! cation:amino acid symporter activity GO:0005416 12 10 0,000 0,01538758 0,03647426 ! startle response GO:0001964 13 10 0,000 0,01538758 0,03645057 ! amyloid precursor protein metabolic process GO:0042982 12 10 0,000 0,01538758 0,03642692 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 12 10 0,000 0,01538758 0,0364033 ! positive regulation of endothelial cell proliferation GO:0001938 13 10 0,000 0,01538758 0,03637971 ! 3'-5'-exoribonuclease activity GO:0000175 10 10 0,000 0,01538758 0,03635614 ! spinal cord patterning GO:0021511 12 10 0,000 0,01538758 0,03633261 ! peptide or protein amino-terminal blocking GO:0018409 11 10 0,000 0,01538758 0,03630911 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 10 10 0,000 0,01538758 0,03628564 GO:0033549|MAP kinase phosphatase activity, ! response to X-ray GO:0010165 11 10 0,000 0,01538758 0,0362622 ! embryonic eye morphogenesis GO:0048048 14 10 0,000 0,01538758 0,03623879 ! sodium:potassium-exchanging ATPase activity GO:0005391 12 10 0,000 0,01538758 0,03621541 ! zinc ion transmembrane transporter activity GO:0005385 13 10 0,000 0,01538758 0,03619206 ! positive regulation of glycogen metabolic process GO:0070875 11 10 0,000 0,01538758 0,03616874 ! glucose transmembrane transporter activity GO:0005355 10 10 0,000 0,01538758 0,03614545 ! regulation of intracellular pH GO:0051453 10 10 0,000 0,01538758 0,03612219 ! retrograde transport, endosome to Golgi GO:0042147 12 10 0,000 0,01538758 0,03609896 ! regulation of multicellular organismal metabolic process GO:0044246 11 10 0,000 0,01538758 0,03607576 ! adult heart development GO:0007512 14 10 0,000 0,01538758 0,03605259 ! neuromuscular junction development GO:0007528 12 10 0,000 0,01538758 0,03602945 ! carbohydrate phosphatase activity GO:0019203 11 10 0,000 0,01538758 0,03600634 ! O-methyltransferase activity GO:0008171 10 10 0,000 0,01538758 0,03598326 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 10 10 0,000 0,01538758 0,03596021 ! signalosome GO:0008180 10 10 0,000 0,01538758 0,03593719 ! lysophospholipase activity GO:0004622 19 10 0,000 0,01538758 0,03591419 ! prefoldin complex GO:0016272 10 10 0,000 0,01538758 0,03589123 ! alpha-beta T cell differentiation GO:0046632 12 10 0,000 0,01538758 0,0358683 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 10 0,000 0,01538758 0,03584539 ! positive regulation of T cell mediated immunity GO:0002711 10 10 0,000 0,01538758 0,03582252 ! nucleoside bisphosphate metabolic process GO:0033865 10 10 0,000 0,01538758 0,03579967 ! endocytic vesicle membrane GO:0030666 10 10 0,000 0,01538758 0,03577685 ! gland morphogenesis GO:0022612 11 10 0,000 0,01538758 0,03575407 ! icosanoid receptor activity GO:0004953 13 10 0,000 0,01538758 0,03573131 GO:0004954|prostanoid receptor activity, ! regulation of macrophage activation GO:0043030 11 10 0,000 0,01538758 0,03570858 ! peptide transporter activity GO:0015197 10 10 0,000 0,01538758 0,03568588 ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 10 10 0,000 0,01538758 0,03566321 ! regulation of leukocyte migration GO:0002685 11 10 0,000 0,01538758 0,03564056 ! muscle maintenance GO:0046716 10 10 0,000 0,01538758 0,03561795 ! acid secretion GO:0046717 12 10 0,000 0,01538758 0,03559536 ! retinoid-X receptor activity GO:0004886 11 10 0,000 0,01538758 0,0355728 ! catecholamine biosynthetic process GO:0042423 11 10 0,000 0,01538758 0,03555028 ! thyroid hormone metabolic process GO:0042403 11 10 0,000 0,01538758 0,03552778 ! GTPase inhibitor activity GO:0005095 21 10 0,000 0,01538758 0,0355053 ! somatic recombination of immunoglobulin gene segments GO:0016447 10 10 0,000 0,01538758 0,03548286 ! pattern recognition receptor activity GO:0008329 10 10 0,000 0,01538758 0,03546045 ! quinone cofactor metabolic process GO:0042375 11 10 0,000 0,01538758 0,03543806 ! regulation of organic acid transport GO:0032890 12 10 0,000 0,01538758 0,0354157 ! platelet-derived growth factor receptor binding GO:0005161 14 10 0,000 0,01538758 0,03539337 ! C-acyltransferase activity GO:0016408 12 10 0,000 0,01538758 0,03537107 ! cAMP-dependent protein kinase complex GO:0005952 12 10 0,000 0,01538758 0,03534879 ! water channel activity GO:0015250 15 10 0,000 0,01538758 0,03532655 ! phospholipase inhibitor activity GO:0004859 10 10 0,000 0,01538758 0,03530433 ! regulation of embryonic development GO:0045995 12 10 0,000 0,01538758 0,03528214 ! acrosome reaction GO:0007340 12 10 0,000 0,01538758 0,03525998 ! mitochondrion localization GO:0051646 10 10 0,000 0,01538758 0,03523784 ! cilium part GO:0044441 10 10 0,000 0,01538758 0,03521574 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 12 11 0,000 0,0169137 0,03868413 ! 'de novo' posttranslational protein folding GO:0051084 11 11 0,000 0,0169137 0,03865989 ! negative regulation of blood pressure GO:0045776 13 11 0,000 0,0169137 0,03863568 ! centriole GO:0005814 11 11 0,000 0,0169137 0,0386115 ! cadmium ion binding GO:0046870 15 11 0,000 0,0169137 0,03858736 ! hemoglobin complex GO:0005833 13 11 0,000 0,0169137 0,03856324 ! CTP metabolic process GO:0046036 13 11 0,000 0,0169137 0,03853915 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0009148|pyrimidine nucleoside triphosphate biosynthetic process, ! regulation of neurotransmitter secretion GO:0046928 12 11 0,000 0,0169137 0,03851509 ! response to pain GO:0048265 12 11 0,000 0,0169137 0,03849107 ! regulation of viral genome replication GO:0045069 13 11 0,000 0,0169137 0,03846707 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 11 11 0,000 0,0169137 0,0384431 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 12 11 0,000 0,0169137 0,03841917 ! nucleotide-sugar metabolic process GO:0009225 13 11 0,000 0,0169137 0,03839526 ! regulation of catecholamine secretion GO:0050433 12 11 0,000 0,0169137 0,03837138 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 0,0169137 0,03834753 ! peptide antigen binding GO:0042605 14 11 0,000 0,0169137 0,03832372 ! polyamine metabolic process GO:0006595 11 11 0,000 0,0169137 0,03829993 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 13 11 0,000 0,0169137 0,03827617 GO:0045125|bioactive lipid receptor activity, ! nucleobase biosynthetic process GO:0046112 13 11 0,000 0,0169137 0,03825244 ! regulation of calcium ion transport into cytosol GO:0010522 15 11 0,000 0,0169137 0,03822874 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 12 11 0,000 0,0169137 0,03820507 GO:0002717|positive regulation of natural killer cell mediated immunity, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 12 11 0,000 0,0169137 0,03818142 ! protein homotetramerization GO:0051289 13 11 0,000 0,0169137 0,03815781 ! regulation of gliogenesis GO:0014013 13 11 0,000 0,0169137 0,03813423 GO:0045685|regulation of glial cell differentiation, ! oligodendrocyte development GO:0014003 11 11 0,000 0,0169137 0,03811067 ! cytoskeletal adaptor activity GO:0008093 17 11 0,000 0,0169137 0,03808715 ! regulation of circadian rhythm GO:0042752 11 11 0,000 0,0169137 0,03806365 ! low-density lipoprotein receptor binding GO:0050750 11 11 0,000 0,0169137 0,03804019 ! response to dsRNA GO:0043331 21 11 0,000 0,0169137 0,03801675 ! response to amine stimulus GO:0014075 15 11 0,000 0,0169137 0,03799334 GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 14 11 0,000 0,0169137 0,03796996 ! sphingomyelin metabolic process GO:0006684 13 11 0,000 0,0169137 0,03794661 ! cell wall macromolecule catabolic process GO:0016998 14 11 0,000 0,0169137 0,03792328 ! spinal cord motor neuron differentiation GO:0021522 12 11 0,000 0,0169137 0,03789999 ! retinal binding GO:0016918 11 11 0,000 0,0169137 0,03787672 ! leukocyte activation during immune response GO:0002366 11 11 0,000 0,0169137 0,03785349 GO:0002263|cell activation during immune response, ! regulation of sterol transport GO:0032371 12 11 0,000 0,0169137 0,03783028 GO:0032374|regulation of cholesterol transport, ! beta-tubulin binding GO:0048487 14 11 0,000 0,0169137 0,0378071 ! autonomic nervous system development GO:0048483 12 11 0,000 0,0169137 0,03778394 ! negative regulation of lipid transport GO:0032369 12 11 0,000 0,0169137 0,03776082 ! photoreceptor outer segment GO:0001750 12 11 0,000 0,0169137 0,03773773 ! positive regulation of interleukin-1 secretion GO:0050716 12 11 0,000 0,0169137 0,03771466 ! peptidyl-threonine modification GO:0018210 15 11 0,000 0,0169137 0,03769162 ! clathrin coat of trans-Golgi network vesicle GO:0030130 15 11 0,000 0,0169137 0,03766861 ! regulation of interleukin-1 beta secretion GO:0050706 12 11 0,000 0,0169137 0,03764563 ! regulation of epidermis development GO:0045682 14 11 0,000 0,0169137 0,03762267 ! positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 11 11 0,000 0,0169137 0,03759975 ! midbrain development GO:0030901 12 11 0,000 0,0169137 0,03757685 ! musculoskeletal movement GO:0050881 12 11 0,000 0,0169137 0,03755398 GO:0050879|multicellular organismal movement, ! histone deacetylase binding GO:0042826 11 11 0,000 0,0169137 0,03753113 ! regulation of RNA stability GO:0043487 13 11 0,000 0,0169137 0,03750832 GO:0043488|regulation of mRNA stability, ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 11 11 0,000 0,0169137 0,03748553 ! cell killing GO:0001906 13 11 0,000 0,0169137 0,03746277 ! regulation of cellular carbohydrate catabolic process GO:0043471 13 11 0,000 0,0169137 0,03744004 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 12 11 0,000 0,0169137 0,03741733 ! carbon-sulfur lyase activity GO:0016846 11 11 0,000 0,0169137 0,03739466 ! cerebellar cortex morphogenesis GO:0021696 13 11 0,000 0,0169137 0,03737201 ! regulation of blood vessel endothelial cell migration GO:0043535 13 11 0,000 0,0169137 0,03734938 ! folic acid binding GO:0005542 12 11 0,000 0,0169137 0,03732679 ! mRNA 3'-end processing GO:0031124 12 11 0,000 0,0169137 0,03730422 ! regulation of calcium-mediated signaling GO:0050848 13 11 0,000 0,0169137 0,03728168 ! positive regulation of protein polymerization GO:0032273 11 11 0,000 0,0169137 0,03725917 ! microspike assembly GO:0030035 15 11 0,000 0,0169137 0,03723668 ! lamellipodium assembly GO:0030032 22 11 0,000 0,0169137 0,03721422 ! fibrillar collagen GO:0005583 12 11 0,000 0,0169137 0,03719179 ! inner ear receptor cell differentiation GO:0060113 12 11 0,000 0,0169137 0,03716939 ! cytoplasmic sequestering of protein GO:0051220 12 11 0,000 0,0169137 0,03714701 ! negative regulation of muscle development GO:0048635 13 11 0,000 0,0169137 0,03712466 ! very-long-chain fatty acid metabolic process GO:0000038 12 11 0,000 0,0169137 0,03710233 ! synaptonemal complex GO:0000795 11 11 0,000 0,0169137 0,03708004 ! reproductive cellular process GO:0048610 13 11 0,000 0,0169137 0,03705777 ! cortical actin cytoskeleton organization GO:0030866 12 11 0,000 0,0169137 0,03703552 ! response to cAMP GO:0051591 11 11 0,000 0,0169137 0,03701331 ! detection of mechanical stimulus GO:0050982 13 11 0,000 0,0169137 0,03699112 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 13 11 0,000 0,0169137 0,03696895 ! regulation of cell projection assembly GO:0060491 11 11 0,000 0,0169137 0,03694682 ! negative regulation of transcription factor import into nucleus GO:0042992 11 11 0,000 0,0169137 0,0369247 ! positive regulation of transcription factor import into nucleus GO:0042993 13 11 0,000 0,0169137 0,03690262 ! macromolecular complex remodeling GO:0034367 11 11 0,000 0,0169137 0,03688056 GO:0034368|protein-lipid complex remodeling, GO:0034369|plasma lipoprotein particle remodeling, ! protein serine/threonine/tyrosine kinase activity GO:0004712 13 11 0,000 0,0169137 0,03685853 ! glycerol ether biosynthetic process GO:0046504 11 11 0,000 0,0169137 0,03683653 ! drug transport GO:0015893 12 11 0,000 0,0169137 0,03681455 ! FMN binding GO:0010181 12 11 0,000 0,0169137 0,03679259 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 11 0,000 0,0169137 0,03677067 ! water transporter activity GO:0005372 17 11 0,000 0,0169137 0,03674877 ! regulation of glycogen metabolic process GO:0070873 12 11 0,000 0,0169137 0,03672689 GO:0032881|regulation of polysaccharide metabolic process, ! substrate-bound cell migration GO:0006929 13 11 0,000 0,0169137 0,03670505 ! multicellular organism growth GO:0035264 12 11 0,000 0,0169137 0,03668322 ! integrator complex GO:0032039 11 11 0,000 0,0169137 0,03666143 ! L-glutamate transmembrane transporter activity GO:0005313 13 11 0,000 0,0169137 0,03663966 GO:0015172|acidic amino acid transmembrane transporter activity, ! DNA integration GO:0015074 11 11 0,000 0,0169137 0,03661791 ! brush border membrane GO:0031526 12 11 0,000 0,0169137 0,03659619 ! actin cytoskeleton reorganization GO:0031532 14 11 0,000 0,0169137 0,0365745 ! negative regulation of caspase activity GO:0043154 12 11 0,000 0,0169137 0,03655283 ! macroautophagy GO:0016236 12 11 0,000 0,0169137 0,03653119 ! protein disulfide oxidoreductase activity GO:0015035 11 11 0,000 0,0169137 0,03650957 ! neuromuscular junction GO:0031594 12 11 0,000 0,0169137 0,03648798 ! positive regulation of peptide secretion GO:0002793 13 11 0,000 0,0169137 0,03646642 ! positive regulation of alpha-beta T cell activation GO:0046635 12 11 0,000 0,0169137 0,03644488 ! organic anion transmembrane transporter activity GO:0008514 11 11 0,000 0,0169137 0,03642337 ! response to antibiotic GO:0046677 13 11 0,000 0,0169137 0,03640188 ! protein-hormone receptor activity GO:0016500 12 11 0,000 0,0169137 0,03638041 ! bile acid transmembrane transporter activity GO:0015125 13 11 0,000 0,0169137 0,03635898 ! proteasome accessory complex GO:0022624 11 11 0,000 0,0169137 0,03633756 ! neuroblast proliferation GO:0007405 13 11 0,000 0,0169137 0,03631618 ! non-G-protein coupled 7TM receptor activity GO:0004926 14 11 0,000 0,0169137 0,03629481 ! negative regulation of neurological system process GO:0031645 13 11 0,000 0,0169137 0,03627348 ! nitric oxide mediated signal transduction GO:0007263 12 11 0,000 0,0169137 0,03625216 ! protein kinase C binding GO:0005080 11 11 0,000 0,0169137 0,03623088 ! transforming growth factor beta receptor, cytoplasmic mediator activity GO:0005072 12 11 0,000 0,0169137 0,03620961 ! male genitalia development GO:0030539 15 11 0,000 0,0169137 0,03618838 ! receptor inhibitor activity GO:0030547 12 11 0,000 0,0169137 0,03616716 GO:0048019|receptor antagonist activity, ! estrogen receptor signaling pathway GO:0030520 12 11 0,000 0,0169137 0,03614598 ! L-fucose metabolic process GO:0042354 13 11 0,000 0,0169137 0,03612481 ! palmitoyltransferase activity GO:0016409 11 11 0,000 0,0169137 0,03610368 ! arylsulfatase activity GO:0004065 12 11 0,000 0,0169137 0,03608256 ! sterol transporter activity GO:0015248 11 11 0,000 0,0169137 0,03606147 ! response to nicotine GO:0035094 13 11 0,000 0,0169137 0,03604041 ! adenylate cyclase activity GO:0004016 11 11 0,000 0,0169137 0,03601937 ! rRNA transcription GO:0009303 12 12 0,000 0,01843754 0,03924163 ! ER-associated protein catabolic process GO:0030433 14 12 0,000 0,01843754 0,03921874 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of blood pressure GO:0045777 15 12 0,000 0,01843754 0,03919589 ! superoxide anion generation GO:0042554 12 12 0,000 0,01843754 0,03917306 ! pteridine and derivative biosynthetic process GO:0042559 22 12 0,000 0,01843754 0,03915026 ! regulation of S phase GO:0033261 16 12 0,000 0,01843754 0,03912748 ! regulation of chemokine production GO:0032642 13 12 0,000 0,01843754 0,03910474 ! male meiosis GO:0007140 12 12 0,000 0,01843754 0,03908201 ! signal complex assembly GO:0007172 15 12 0,000 0,01843754 0,03905932 ! positive regulation of GTPase activity GO:0043547 17 12 0,000 0,01843754 0,03903665 ! GTP metabolic process GO:0046039 14 12 0,000 0,01843754 0,03901401 ! retina morphogenesis in camera-type eye GO:0060042 16 12 0,000 0,01843754 0,03899139 ! hair follicle morphogenesis GO:0031069 14 12 0,000 0,01843754 0,0389688 ! voltage-gated sodium channel complex GO:0001518 15 12 0,000 0,01843754 0,03894623 GO:0034706|sodium channel complex, ! RNA polyadenylation GO:0043631 13 12 0,000 0,01843754 0,0389237 ! cartilage condensation GO:0001502 14 12 0,000 0,01843754 0,03890118 ! polysome GO:0005844 14 12 0,000 0,01843754 0,0388787 ! hippocampus development GO:0021766 13 12 0,000 0,01843754 0,03885624 ! lipoprotein receptor binding GO:0070325 13 12 0,000 0,01843754 0,0388338 ! beta-amyloid binding GO:0001540 12 12 0,000 0,01843754 0,03881139 ! negative regulation of endocytosis GO:0045806 15 12 0,000 0,01843754 0,03878901 ! regulation of interferon-gamma biosynthetic process GO:0045072 15 12 0,000 0,01843754 0,03876665 ! regulation of exit from mitosis GO:0007096 31 12 0,000 0,01843754 0,03874432 ! chylomicron GO:0042627 13 12 0,000 0,01843754 0,03872202 ! T cell selection GO:0045058 22 12 0,000 0,01843754 0,03869974 ! negative regulation of proteolysis GO:0045861 12 12 0,000 0,01843754 0,03867748 ! glycolipid biosynthetic process GO:0009247 13 12 0,000 0,01843754 0,03865526 ! WW domain binding GO:0050699 12 12 0,000 0,01843754 0,03863305 ! methionine metabolic process GO:0006555 14 12 0,000 0,01843754 0,03861088 ! nuclear heterochromatin GO:0005720 12 12 0,000 0,01843754 0,03858872 ! glycine metabolic process GO:0006544 14 12 0,000 0,01843754 0,0385666 ! plasma membrane organization GO:0007009 12 12 0,000 0,01843754 0,0385445 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01843754 0,03852242 ! ribonucleotide catabolic process GO:0009261 12 12 0,000 0,01843754 0,03850037 ! Golgi organization GO:0007030 15 12 0,000 0,01843754 0,03847834 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 0,01843754 0,03845634 ! mitotic spindle organization GO:0007052 13 12 0,000 0,01843754 0,03843437 ! integral to peroxisomal membrane GO:0005779 12 12 0,000 0,01843754 0,03841242 ! integral to membrane of membrane fraction GO:0000299 13 12 0,000 0,01843754 0,03839049 ! regulation of the force of heart contraction GO:0002026 13 12 0,000 0,01843754 0,03836859 ! temperature homeostasis GO:0001659 13 12 0,000 0,01843754 0,03834672 ! negative regulation of mitotic cell cycle GO:0045930 15 12 0,000 0,01843754 0,03832487 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 0,01843754 0,03830304 ! lipoprotein receptor activity GO:0030228 12 12 0,000 0,01843754 0,03828124 ! cotranslational protein targeting to membrane GO:0006613 14 12 0,000 0,01843754 0,03825947 ! axon cargo transport GO:0008088 13 12 0,000 0,01843754 0,03823772 ! regulation of phagocytosis GO:0050764 14 12 0,000 0,01843754 0,03821599 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 12 0,000 0,01843754 0,03819429 ! nucleoside triphosphate catabolic process GO:0009143 12 12 0,000 0,01843754 0,03817261 ! transcription elongation factor complex GO:0008023 12 12 0,000 0,01843754 0,03815096 ! basal lamina GO:0005605 12 12 0,000 0,01843754 0,03812933 ! regulation of interleukin-1 secretion GO:0050704 13 12 0,000 0,01843754 0,03810773 ! pancreatic ribonuclease activity GO:0004522 12 12 0,000 0,01843754 0,03808615 ! tRNA-specific ribonuclease activity GO:0004549 12 12 0,000 0,01843754 0,0380646 ! biomineral formation GO:0031214 14 12 0,000 0,01843754 0,03804307 ! water homeostasis GO:0030104 12 12 0,000 0,01843754 0,03802156 ! promoter binding GO:0010843 14 12 0,000 0,01843754 0,03800008 ! regulation of erythrocyte differentiation GO:0045646 15 12 0,000 0,01843754 0,03797863 ! intestinal absorption GO:0050892 14 12 0,000 0,01843754 0,03795719 ! pseudouridine synthase activity GO:0009982 12 12 0,000 0,01843754 0,03793578 ! oocyte differentiation GO:0009994 13 12 0,000 0,01843754 0,0379144 ! oxygen transport GO:0015671 13 12 0,000 0,01843754 0,03789304 GO:0005344|oxygen transporter activity, ! thymus development GO:0048538 13 12 0,000 0,01843754 0,0378717 ! cholesterol efflux GO:0033344 13 12 0,000 0,01843754 0,03785039 ! digestive tract morphogenesis GO:0048546 14 12 0,000 0,01843754 0,0378291 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! racemase and epimerase activity GO:0016854 13 12 0,000 0,01843754 0,03780784 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 14 12 0,000 0,01843754 0,0377866 ! tropomyosin binding GO:0005523 12 12 0,000 0,01843754 0,03776538 ! blastocyst formation GO:0001825 13 12 0,000 0,01843754 0,03774419 ! regulation of telomere maintenance GO:0032204 16 12 0,000 0,01843754 0,03772302 ! internal side of plasma membrane GO:0009898 16 12 0,000 0,01843754 0,03770188 ! mannose binding GO:0005537 13 12 0,000 0,01843754 0,03768075 ! phosphoprotein binding GO:0051219 14 12 0,000 0,01843754 0,03765966 ! defense response to fungus GO:0050832 12 12 0,000 0,01843754 0,03763858 ! embryonic placenta development GO:0001892 16 12 0,000 0,01843754 0,03761753 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 0,01843754 0,0375965 ! cell wall macromolecule metabolic process GO:0044036 15 12 0,000 0,01843754 0,0375755 ! acyl-CoA binding GO:0000062 12 12 0,000 0,01843754 0,03755452 ! cortical cytoskeleton organization GO:0030865 13 12 0,000 0,01843754 0,03753356 ! regulation of nitric-oxide synthase activity GO:0050999 12 12 0,000 0,01843754 0,03751263 ! copper ion transport GO:0006825 12 12 0,000 0,01843754 0,03749172 ! calcium ion transport into cytosol GO:0060402 19 12 0,000 0,01843754 0,03747083 ! inositol metabolic process GO:0006020 21 12 0,000 0,01843754 0,03744997 ! vesicle targeting, to, from or within Golgi GO:0048199 13 12 0,000 0,01843754 0,03742913 ! forelimb morphogenesis GO:0035136 15 12 0,000 0,01843754 0,03740831 ! protein complex disassembly GO:0043241 15 12 0,000 0,01843754 0,03738752 GO:0043624|cellular protein complex disassembly, ! ion channel inhibitor activity GO:0008200 15 12 0,000 0,01843754 0,03736675 GO:0016248|channel inhibitor activity, ! low-density lipoprotein particle GO:0034362 13 12 0,000 0,01843754 0,037346 ! lipoprotein particle clearance GO:0034381 14 12 0,000 0,01843754 0,03732528 ! receptor signaling protein tyrosine kinase activity GO:0004716 14 12 0,000 0,01843754 0,03730457 ! endothelial cell differentiation GO:0045446 15 12 0,000 0,01843754 0,03728389 ! exosome (RNase complex) GO:0000178 13 12 0,000 0,01843754 0,03726324 ! DNA N-glycosylase activity GO:0019104 12 12 0,000 0,01843754 0,03724261 ! endoderm development GO:0007492 13 12 0,000 0,01843754 0,037222 ! positive regulation of Ras protein signal transduction GO:0046579 25 12 0,000 0,01843754 0,03720141 ! focal adhesion formation GO:0048041 16 12 0,000 0,01843754 0,03718084 ! T cell receptor complex GO:0042101 31 12 0,000 0,01843754 0,0371603 ! cellular carbohydrate catabolic process GO:0044275 25 12 0,000 0,01843754 0,03713978 ! dicarboxylic acid transmembrane transporter activity GO:0005310 14 12 0,000 0,01843754 0,03711929 ! CoA hydrolase activity GO:0016289 14 12 0,000 0,01843754 0,03709881 ! histone acetyltransferase complex GO:0000123 14 12 0,000 0,01843754 0,03707836 ! regulation of alpha-beta T cell differentiation GO:0046637 13 12 0,000 0,01843754 0,03705793 ! alpha-beta T cell activation GO:0046631 14 12 0,000 0,01843754 0,03703753 ! retinol binding GO:0019841 12 12 0,000 0,01843754 0,03701714 ! regulation of organ growth GO:0046620 12 12 0,000 0,01843754 0,03699678 ! regulation of natural killer cell mediated immunity GO:0002715 13 12 0,000 0,01843754 0,03697644 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! vasoconstriction GO:0042310 13 12 0,000 0,01843754 0,03695612 ! histone acetylation GO:0016573 13 12 0,000 0,01843754 0,03693583 ! ribosome binding GO:0043022 13 12 0,000 0,01843754 0,03691556 ! delayed rectifier potassium channel activity GO:0005251 14 12 0,000 0,01843754 0,03689531 ! organic cation transmembrane transporter activity GO:0015101 12 12 0,000 0,01843754 0,03687508 ! phosphate transmembrane transporter activity GO:0015114 14 12 0,000 0,01843754 0,03685487 ! tissue regeneration GO:0042246 12 12 0,000 0,01843754 0,03683469 ! sulfate transmembrane transporter activity GO:0015116 13 12 0,000 0,01843754 0,03681453 ! adenylyltransferase activity GO:0070566 13 12 0,000 0,01843754 0,03679439 ! germ cell nucleus GO:0043073 14 12 0,000 0,01843754 0,03677427 ! trans-Golgi network transport vesicle membrane GO:0012510 16 12 0,000 0,01843754 0,03675418 ! hexose transmembrane transporter activity GO:0015149 12 12 0,000 0,01843754 0,0367341 ! hexosaminidase activity GO:0015929 12 12 0,000 0,01843754 0,03671405 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 0,01843754 0,03669402 ! activation of NF-kappaB-inducing kinase activity GO:0007250 14 12 0,000 0,01843754 0,03667402 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 13 12 0,000 0,01843754 0,03665403 ! dopamine metabolic process GO:0042417 15 12 0,000 0,01843754 0,03663407 ! somatic diversification of immunoglobulins GO:0016445 12 12 0,000 0,01843754 0,03661412 ! phosphoinositide 3-kinase activity GO:0035004 14 12 0,000 0,01843754 0,0365942 ! insulin-like growth factor receptor binding GO:0005159 14 12 0,000 0,01843754 0,0365743 ! bacterial binding GO:0008367 14 12 0,000 0,01843754 0,03655443 ! steroid hydroxylase activity GO:0008395 12 12 0,000 0,01843754 0,03653457 ! cardiac cell differentiation GO:0035051 16 12 0,000 0,01843754 0,03651474 ! phosphoinositide 3-kinase complex GO:0005942 14 12 0,000 0,01843754 0,03649492 ! localization within membrane GO:0051668 13 12 0,000 0,01843754 0,03647513 ! microtubule-based flagellum GO:0009434 12 12 0,000 0,01843754 0,03645536 ! axoneme part GO:0044447 12 12 0,000 0,01843754 0,03643562 ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,0199591 0,03942111 ! neuron maturation GO:0042551 14 13 0,000 0,0199591 0,03939978 ! positive regulation of small GTPase mediated signal transduction GO:0051057 26 13 0,000 0,0199591 0,03937847 ! negative regulation of bone remodeling GO:0046851 15 13 0,000 0,0199591 0,03935718 ! bone remodeling GO:0046849 14 13 0,000 0,0199591 0,03933592 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,0199591 0,03931468 ! regulation of receptor-mediated endocytosis GO:0048259 15 13 0,000 0,0199591 0,03929346 ! striated muscle thin filament GO:0005865 14 13 0,000 0,0199591 0,03927227 ! patterning of blood vessels GO:0001569 15 13 0,000 0,0199591 0,0392511 ! organelle fusion GO:0048284 16 13 0,000 0,0199591 0,03922995 ! palate development GO:0060021 15 13 0,000 0,0199591 0,03920883 ! induction of apoptosis via death domain receptors GO:0008625 16 13 0,000 0,0199591 0,03918772 ! arginine metabolic process GO:0006525 14 13 0,000 0,0199591 0,03916664 ! ER-Golgi intermediate compartment membrane GO:0033116 23 13 0,000 0,0199591 0,03914559 ! tyrosine metabolic process GO:0006570 15 13 0,000 0,0199591 0,03912455 ! response to retinoic acid GO:0032526 17 13 0,000 0,0199591 0,03910354 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 15 13 0,000 0,0199591 0,03908255 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lipase inhibitor activity GO:0055102 14 13 0,000 0,0199591 0,03906158 ! negative regulation of endothelial cell migration GO:0010596 15 13 0,000 0,0199591 0,03904064 ! fear response GO:0042596 15 13 0,000 0,0199591 0,03901972 ! epithelial cell development GO:0002064 22 13 0,000 0,0199591 0,03899882 ! branching involved in ureteric bud morphogenesis GO:0001658 14 13 0,000 0,0199591 0,03897794 GO:0060675|ureteric bud morphogenesis, ! positive regulation of fatty acid metabolic process GO:0045923 14 13 0,000 0,0199591 0,03895708 ! protein kinase activator activity GO:0030295 17 13 0,000 0,0199591 0,03893625 ! heparan sulfate proteoglycan metabolic process GO:0030201 13 13 0,000 0,0199591 0,03891544 ! positive regulation of foam cell differentiation GO:0010744 16 13 0,000 0,0199591 0,03889465 ! protein targeting to peroxisome GO:0006625 13 13 0,000 0,0199591 0,03887389 ! NLS-bearing substrate import into nucleus GO:0006607 15 13 0,000 0,0199591 0,03885314 ! cranial nerve development GO:0021545 15 13 0,000 0,0199591 0,03883242 ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,0199591 0,03881172 ! cerebellum morphogenesis GO:0021587 15 13 0,000 0,0199591 0,03879104 ! MHC class I receptor activity GO:0032393 20 13 0,000 0,0199591 0,03877039 ! exoribonuclease activity GO:0004532 13 13 0,000 0,0199591 0,03874976 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! intrinsic to peroxisomal membrane GO:0031231 13 13 0,000 0,0199591 0,03872914 ! COPI-coated vesicle GO:0030137 15 13 0,000 0,0199591 0,03870855 ! cofactor transporter activity GO:0051184 15 13 0,000 0,0199591 0,03868799 ! NADP metabolic process GO:0006739 15 13 0,000 0,0199591 0,03866744 ! negative regulation of macrophage differentiation GO:0045650 16 13 0,000 0,0199591 0,03864692 ! regulation of osteoclast differentiation GO:0045670 15 13 0,000 0,0199591 0,03862641 ! aromatic amino acid family catabolic process GO:0009074 13 13 0,000 0,0199591 0,03860593 ! eukaryotic cell surface binding GO:0043499 15 13 0,000 0,0199591 0,03858547 ! proximal/distal pattern formation GO:0009954 15 13 0,000 0,0199591 0,03856504 ! positive regulation of JNK cascade GO:0046330 17 13 0,000 0,0199591 0,03854462 ! positive regulation of glucose import GO:0046326 16 13 0,000 0,0199591 0,03852423 GO:0010828|positive regulation of glucose transport, ! epithelial to mesenchymal transition GO:0001837 13 13 0,000 0,0199591 0,03850386 ! ADP binding GO:0043531 15 13 0,000 0,0199591 0,0384835 ! defense response to Gram-positive bacterium GO:0050830 14 13 0,000 0,0199591 0,03846318 ! mismatched DNA binding GO:0030983 13 13 0,000 0,0199591 0,03844287 ! positive regulation of synaptic transmission GO:0050806 15 13 0,000 0,0199591 0,03842258 ! neuron fate specification GO:0048665 25 13 0,000 0,0199591 0,03840232 ! N-terminal protein amino acid modification GO:0031365 14 13 0,000 0,0199591 0,03838207 ! dicarboxylic acid transport GO:0006835 15 13 0,000 0,0199591 0,03836185 ! water transport GO:0006833 18 13 0,000 0,0199591 0,03834165 GO:0042044|fluid transport, ! replisome GO:0030894 24 13 0,000 0,0199591 0,03832147 GO:0043601|nuclear replisome, ! cytosolic calcium ion transport GO:0060401 20 13 0,000 0,0199591 0,03830131 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,0199591 0,03828117 ! inorganic anion exchanger activity GO:0005452 13 13 0,000 0,0199591 0,03826106 ! negative regulation of ion transport GO:0043271 15 13 0,000 0,0199591 0,03824096 ! retinoic acid receptor binding GO:0042974 14 13 0,000 0,0199591 0,03822089 ! blood vessel remodeling GO:0001974 16 13 0,000 0,0199591 0,03820083 ! myoblast differentiation GO:0045445 15 13 0,000 0,0199591 0,0381808 ! ventral spinal cord development GO:0021517 16 13 0,000 0,0199591 0,03816079 ! prenyltransferase activity GO:0004659 15 13 0,000 0,0199591 0,0381408 ! activation of MAPKK activity GO:0000186 13 13 0,000 0,0199591 0,03812083 ! protein histidine kinase activity GO:0004673 15 13 0,000 0,0199591 0,03810088 GO:0000155|two-component sensor activity, ! cullin-RING ubiquitin ligase complex GO:0031461 13 13 0,000 0,0199591 0,03808096 ! regulation of skeletal muscle fiber development GO:0048742 16 13 0,000 0,0199591 0,03806105 ! acyl-CoA dehydrogenase activity GO:0003995 14 13 0,000 0,0199591 0,03804117 ! exocrine system development GO:0035272 14 13 0,000 0,0199591 0,0380213 ! membrane protein proteolysis GO:0033619 14 13 0,000 0,0199591 0,03800146 GO:0006509|membrane protein ectodomain proteolysis, ! organic alcohol transport GO:0015850 17 13 0,000 0,0199591 0,03798163 ! calcium ion transmembrane transporter activity GO:0015085 15 13 0,000 0,0199591 0,03796183 ! L-glutamate transport GO:0015813 14 13 0,000 0,0199591 0,03794205 GO:0015800|acidic amino acid transport, ! embryo implantation GO:0007566 17 13 0,000 0,0199591 0,03792229 ! G1/S transition checkpoint GO:0031575 14 13 0,000 0,0199591 0,03790255 ! immunoglobulin binding GO:0019865 14 13 0,000 0,0199591 0,03788283 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,0199591 0,03786313 ! regulation of T cell mediated immunity GO:0002709 17 13 0,000 0,0199591 0,03784345 ! DNA unwinding during replication GO:0006268 14 13 0,000 0,0199591 0,03782379 ! genitalia development GO:0048806 18 13 0,000 0,0199591 0,03780415 ! regulation of interleukin-8 production GO:0032677 15 13 0,000 0,0199591 0,03778453 ! regulation of interleukin-12 production GO:0032655 13 13 0,000 0,0199591 0,03776493 ! MHC class I protein binding GO:0042288 23 13 0,000 0,0199591 0,03774536 ! histone deacetylation GO:0016575 14 13 0,000 0,0199591 0,0377258 ! calcium channel regulator activity GO:0005246 16 13 0,000 0,0199591 0,03770626 ! DNA methylation GO:0006306 15 13 0,000 0,0199591 0,03768674 GO:0006305|DNA alkylation, ! mRNA splice site selection GO:0006376 17 13 0,000 0,0199591 0,03766725 ! chromatin silencing GO:0006342 13 13 0,000 0,0199591 0,03764777 ! serotonin receptor activity GO:0004993 16 13 0,000 0,0199591 0,03762832 ! monosaccharide transmembrane transporter activity GO:0015145 13 13 0,000 0,0199591 0,03760888 ! T cell homeostasis GO:0043029 14 13 0,000 0,0199591 0,03758946 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,0199591 0,03757007 ! diacylglycerol kinase activity GO:0004143 15 13 0,000 0,0199591 0,03755069 ! response to gamma radiation GO:0010332 14 13 0,000 0,0199591 0,03753134 ! synaptic transmission, cholinergic GO:0007271 14 13 0,000 0,0199591 0,037512 ! retinoic acid receptor activity GO:0003708 15 13 0,000 0,0199591 0,03749268 ! purine base metabolic process GO:0006144 15 13 0,000 0,0199591 0,03747339 ! cAMP binding GO:0030552 15 13 0,000 0,0199591 0,03745411 ! biogenic amine catabolic process GO:0042402 14 13 0,000 0,0199591 0,03743485 ! negative regulation of BMP signaling pathway GO:0030514 14 13 0,000 0,0199591 0,03741562 ! regulation of axon extension GO:0030516 16 13 0,000 0,0199591 0,0373964 ! drug transporter activity GO:0015238 14 13 0,000 0,0199591 0,0373772 ! regulation of NF-kappaB import into nucleus GO:0042345 14 13 0,000 0,0199591 0,03735802 ! calcium-activated potassium channel activity GO:0015269 15 13 0,000 0,0199591 0,03733887 ! response to cold GO:0009409 13 13 0,000 0,0199591 0,03731973 ! cadherin binding GO:0045296 16 13 0,000 0,0199591 0,03730061 ! nucleolar part GO:0044452 13 13 0,000 0,0199591 0,03728151 ! tRNA modification GO:0006400 14 14 0,000 0,02147838 0,04009884 ! cis-Golgi network GO:0005801 16 14 0,000 0,02147838 0,04007833 ! negative regulation of hormone secretion GO:0046888 14 14 0,000 0,02147838 0,04005784 ! 'de novo' protein folding GO:0006458 14 14 0,000 0,02147838 0,04003737 ! organellar large ribosomal subunit GO:0000315 15 14 0,000 0,02147838 0,04001692 GO:0005762|mitochondrial large ribosomal subunit, ! phosphoinositide phosphorylation GO:0046854 18 14 0,000 0,02147838 0,03999649 ! peroxisomal transport GO:0043574 14 14 0,000 0,02147838 0,03997609 ! cardiac muscle contraction GO:0060048 15 14 0,000 0,02147838 0,0399557 ! dopamine receptor signaling pathway GO:0007212 19 14 0,000 0,02147838 0,03993533 ! mechanoreceptor differentiation GO:0042490 16 14 0,000 0,02147838 0,03991499 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 18 14 0,000 0,02147838 0,03989467 ! negative regulation of peptidase activity GO:0010466 16 14 0,000 0,02147838 0,03987436 ! pseudouridine synthesis GO:0001522 14 14 0,000 0,02147838 0,03985408 ! positive regulation of cell growth GO:0030307 15 14 0,000 0,02147838 0,03983382 ! caspase activator activity GO:0008656 16 14 0,000 0,02147838 0,03981358 ! MHC class II protein complex GO:0042613 19 14 0,000 0,02147838 0,03979336 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,02147838 0,03977316 ! cAMP-dependent protein kinase regulator activity GO:0008603 17 14 0,000 0,02147838 0,03975298 ! cation:cation antiporter activity GO:0015491 14 14 0,000 0,02147838 0,03973282 ! glycoprotein catabolic process GO:0006516 16 14 0,000 0,02147838 0,03971268 ! protein polyubiquitination GO:0000209 15 14 0,000 0,02147838 0,03969257 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 34 14 0,000 0,02147838 0,03967247 ! negative regulation of microtubule depolymerization GO:0007026 16 14 0,000 0,02147838 0,03965239 GO:0031114|regulation of microtubule depolymerization, ! cell-cell junction assembly GO:0007043 15 14 0,000 0,02147838 0,03963234 ! response to vitamin A GO:0033189 18 14 0,000 0,02147838 0,0396123 ! actin filament bundle formation GO:0051017 16 14 0,000 0,02147838 0,03959228 ! regulation of lipoprotein lipase activity GO:0051004 15 14 0,000 0,02147838 0,03957229 ! plasma membrane fusion GO:0045026 15 14 0,000 0,02147838 0,03955231 ! purine nucleoside monophosphate metabolic process GO:0009126 15 14 0,000 0,02147838 0,03953235 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 16 14 0,000 0,02147838 0,03951242 ! protein export from nucleus GO:0006611 14 14 0,000 0,02147838 0,0394925 ! presynaptic membrane GO:0042734 14 14 0,000 0,02147838 0,03947261 ! negative regulation of immune response GO:0050777 21 14 0,000 0,02147838 0,03945273 ! gastrulation with mouth forming second GO:0001702 15 14 0,000 0,02147838 0,03943288 ! neural crest cell migration GO:0001755 15 14 0,000 0,02147838 0,03941304 ! anaphase-promoting complex GO:0005680 17 14 0,000 0,02147838 0,03939323 ! positive regulation of oxidoreductase activity GO:0051353 14 14 0,000 0,02147838 0,03937343 ! negative regulation of protein secretion GO:0050709 17 14 0,000 0,02147838 0,03935365 ! cofactor transport GO:0051181 16 14 0,000 0,02147838 0,0393339 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,02147838 0,03931416 ! protein-chromophore linkage GO:0018298 16 14 0,000 0,02147838 0,03929445 ! cobalt ion binding GO:0050897 14 14 0,000 0,02147838 0,03927475 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,02147838 0,03925507 ! positive regulation of transmission of nerve impulse GO:0051971 16 14 0,000 0,02147838 0,03923542 ! aspartate family amino acid biosynthetic process GO:0009067 17 14 0,000 0,02147838 0,03921578 ! gas transport GO:0015669 15 14 0,000 0,02147838 0,03919616 ! pyridine nucleotide biosynthetic process GO:0019363 15 14 0,000 0,02147838 0,03917656 ! heme biosynthetic process GO:0006783 14 14 0,000 0,02147838 0,03915698 ! release of cytochrome c from mitochondria GO:0001836 26 14 0,000 0,02147838 0,03913743 ! cerebellar cortex development GO:0021695 16 14 0,000 0,02147838 0,03911789 ! insulin secretion GO:0030073 17 14 0,000 0,02147838 0,03909837 ! tRNA binding GO:0000049 16 14 0,000 0,02147838 0,03907887 ! positive regulation of cell killing GO:0031343 16 14 0,000 0,02147838 0,03905939 ! positive regulation of protein complex assembly GO:0031334 14 14 0,000 0,02147838 0,03903992 ! G1 phase of mitotic cell cycle GO:0000080 15 14 0,000 0,02147838 0,03902048 ! phosphatidylinositol metabolic process GO:0046488 15 14 0,000 0,02147838 0,03900106 ! regulation of neuronal synaptic plasticity GO:0048168 24 14 0,000 0,02147838 0,03898166 ! MAP kinase activity GO:0004707 16 14 0,000 0,02147838 0,03896227 ! cytokine biosynthetic process GO:0042089 14 14 0,000 0,02147838 0,03894291 ! mannosyltransferase activity GO:0000030 14 14 0,000 0,02147838 0,03892356 ! isoprenoid biosynthetic process GO:0008299 17 14 0,000 0,02147838 0,03890423 ! C-C chemokine binding GO:0019957 15 14 0,000 0,02147838 0,03888493 GO:0016493|C-C chemokine receptor activity, ! cardiac muscle tissue development GO:0048738 16 14 0,000 0,02147838 0,03886564 ! complement activation, alternative pathway GO:0006957 14 14 0,000 0,02147838 0,03884637 ! response to osmotic stress GO:0006970 17 14 0,000 0,02147838 0,03882712 ! fructose metabolic process GO:0006000 15 14 0,000 0,02147838 0,03880789 ! telomeric DNA binding GO:0042162 17 14 0,000 0,02147838 0,03878868 ! monoamine transport GO:0015844 15 14 0,000 0,02147838 0,03876948 ! regulation of pathway-restricted SMAD protein phosphorylation GO:0060393 14 14 0,000 0,02147838 0,03875031 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,02147838 0,03873116 ! dendritic spine GO:0043197 15 14 0,000 0,02147838 0,03871202 ! stem cell development GO:0048864 14 14 0,000 0,02147838 0,0386929 GO:0019827|stem cell maintenance, ! regulation of alpha-beta T cell activation GO:0046634 15 14 0,000 0,02147838 0,0386738 ! regulation of insulin receptor signaling pathway GO:0046626 17 14 0,000 0,02147838 0,03865472 ! regulation of cytokine production during immune response GO:0002718 15 14 0,000 0,02147838 0,03863566 ! positive regulation of protein import into nucleus GO:0042307 16 14 0,000 0,02147838 0,03861662 ! regulation of cellular pH GO:0030641 14 14 0,000 0,02147838 0,0385976 ! regulation of monooxygenase activity GO:0032768 14 14 0,000 0,02147838 0,0385786 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,02147838 0,03855961 ! sarcoplasmic reticulum membrane GO:0033017 16 14 0,000 0,02147838 0,03854064 ! detection of biotic stimulus GO:0009595 16 14 0,000 0,02147838 0,03852169 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 16 14 0,000 0,02147838 0,03850277 ! mannosidase activity GO:0015923 19 14 0,000 0,02147838 0,03848385 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 17 14 0,000 0,02147838 0,03846496 ! negative regulation of tissue remodeling GO:0034104 16 14 0,000 0,02147838 0,03844609 ! positive regulation of bone mineralization GO:0030501 14 14 0,000 0,02147838 0,03842723 ! neuromuscular synaptic transmission GO:0007274 15 14 0,000 0,02147838 0,0384084 ! regulation of immunoglobulin production GO:0002637 15 14 0,000 0,02147838 0,03838958 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,02147838 0,03837078 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 16 14 0,000 0,02147838 0,038352 ! fucosyltransferase activity GO:0008417 16 14 0,000 0,02147838 0,03833323 ! sperm-egg recognition GO:0035036 17 14 0,000 0,02147838 0,03831449 GO:0007339|binding of sperm to zona pellucida, ! defense response to virus GO:0051607 21 14 0,000 0,02147838 0,03829576 ! SWI/SNF-type complex GO:0070603 16 14 0,000 0,02147838 0,03827705 GO:0016514|SWI/SNF complex, ! aldo-keto reductase activity GO:0004033 15 14 0,000 0,02147838 0,03825836 ! positive regulation of translation GO:0045727 17 15 0,000 0,02299539 0,04094054 ! nuclear replication fork GO:0043596 26 15 0,000 0,02299539 0,04092057 ! transferase activity, transferring amino-acyl groups GO:0016755 15 15 0,000 0,02299539 0,04090062 ! 2'-deoxyribonucleotide metabolic process GO:0009394 16 15 0,000 0,02299539 0,04088069 GO:0019692|deoxyribose phosphate metabolic process, ! phospholipid catabolic process GO:0009395 26 15 0,000 0,02299539 0,04086077 ! endothelial cell migration GO:0043542 16 15 0,000 0,02299539 0,04084088 ! lipid phosphorylation GO:0046834 19 15 0,000 0,02299539 0,04082101 ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,02299539 0,04080115 ! response to vitamin GO:0033273 19 15 0,000 0,02299539 0,04078132 ! gene silencing by RNA GO:0031047 17 15 0,000 0,02299539 0,0407615 ! striated muscle thick filament GO:0005863 16 15 0,000 0,02299539 0,0407417 GO:0032982|myosin filament, ! cellular response to hydrogen peroxide GO:0070301 15 15 0,000 0,02299539 0,04072193 GO:0042744|hydrogen peroxide catabolic process, ! endocrine pancreas development GO:0031018 16 15 0,000 0,02299539 0,04070217 ! regulation of interleukin-2 biosynthetic process GO:0045076 15 15 0,000 0,02299539 0,04068243 ! glutamate metabolic process GO:0006536 17 15 0,000 0,02299539 0,04066271 ! pituitary gland development GO:0021983 16 15 0,000 0,02299539 0,04064301 ! cholesterol binding GO:0015485 15 15 0,000 0,02299539 0,04062333 ! NAD metabolic process GO:0019674 17 15 0,000 0,02299539 0,04060366 ! protease binding GO:0002020 20 15 0,000 0,02299539 0,04058402 ! regulation of heart rate GO:0002027 20 15 0,000 0,02299539 0,04056439 ! actin filament bundle GO:0032432 18 15 0,000 0,02299539 0,04054479 GO:0001725|stress fiber, ! Golgi cisterna GO:0031985 17 15 0,000 0,02299539 0,0405252 ! regulation of exocytosis GO:0017157 16 15 0,000 0,02299539 0,04050563 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,02299539 0,04048608 ! embryonic digit morphogenesis GO:0042733 17 15 0,000 0,02299539 0,04046655 ! positive regulation of biomineral formation GO:0070169 15 15 0,000 0,02299539 0,04044704 ! prostaglandin metabolic process GO:0006693 15 15 0,000 0,02299539 0,04042755 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 20 15 0,000 0,02299539 0,04040808 ! neuron recognition GO:0008038 18 15 0,000 0,02299539 0,04038862 ! regulation of Rho GTPase activity GO:0032319 18 15 0,000 0,02299539 0,04036919 ! hindbrain morphogenesis GO:0021575 18 15 0,000 0,02299539 0,04034977 ! filopodium GO:0030175 17 15 0,000 0,02299539 0,04033037 ! negative regulation of blood coagulation GO:0030195 18 15 0,000 0,02299539 0,04031099 ! folic acid and derivative metabolic process GO:0006760 15 15 0,000 0,02299539 0,04029163 ! positive regulation of neuron differentiation GO:0045666 27 15 0,000 0,02299539 0,04027228 ! peptide hormone binding GO:0017046 16 15 0,000 0,02299539 0,04025296 ! regulation of ATPase activity GO:0043462 17 15 0,000 0,02299539 0,04023365 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 16 15 0,000 0,02299539 0,04021437 ! regulation of leukocyte mediated cytotoxicity GO:0001910 21 15 0,000 0,02299539 0,0401951 ! acid-thiol ligase activity GO:0016878 16 15 0,000 0,02299539 0,04017585 ! aromatic compound biosynthetic process GO:0019438 25 15 0,000 0,02299539 0,04015661 ! positive regulation of calcium ion transport GO:0051928 20 15 0,000 0,02299539 0,0401374 ! dystrophin-associated glycoprotein complex GO:0016010 17 15 0,000 0,02299539 0,04011821 ! RNA 3'-end processing GO:0031123 16 15 0,000 0,02299539 0,04009903 ! developmental induction GO:0031128 17 15 0,000 0,02299539 0,04007987 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 17 15 0,000 0,02299539 0,04006073 ! protein import into nucleus, docking GO:0000059 15 15 0,000 0,02299539 0,04004161 ! regulation of skeletal muscle tissue development GO:0048641 18 15 0,000 0,02299539 0,0400225 ! lactation GO:0007595 17 15 0,000 0,02299539 0,04000342 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 16 15 0,000 0,02299539 0,03998435 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02299539 0,0399653 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,02299539 0,03994627 ! double-strand break repair via homologous recombination GO:0000724 36 15 0,000 0,02299539 0,03992726 GO:0000725|recombinational repair, ! phosphatidylcholine metabolic process GO:0046470 16 15 0,000 0,02299539 0,03990826 ! regulation of cell-cell adhesion GO:0022407 18 15 0,000 0,02299539 0,03988929 ! sulfate transport GO:0008272 16 15 0,000 0,02299539 0,03987033 ! hindlimb morphogenesis GO:0035137 17 15 0,000 0,02299539 0,03985139 ! bile acid metabolic process GO:0008206 17 15 0,000 0,02299539 0,03983246 ! very-low-density lipoprotein particle GO:0034361 16 15 0,000 0,02299539 0,03981356 GO:0034385|triglyceride-rich lipoprotein particle, ! adult walking behavior GO:0007628 19 15 0,000 0,02299539 0,03979467 ! 2 iron, 2 sulfur cluster binding GO:0051537 16 15 0,000 0,02299539 0,0397758 ! heart looping GO:0001947 18 15 0,000 0,02299539 0,03975695 ! oligodendrocyte differentiation GO:0048709 15 15 0,000 0,02299539 0,03973812 ! regulation of striated muscle contraction GO:0006942 18 15 0,000 0,02299539 0,0397193 ! pigmentation during development GO:0048066 17 15 0,000 0,02299539 0,03970051 ! cytokine metabolic process GO:0042107 15 15 0,000 0,02299539 0,03968173 ! vesicle coating GO:0006901 17 15 0,000 0,02299539 0,03966296 ! disulfide oxidoreductase activity GO:0015036 16 15 0,000 0,02299539 0,03964422 ! neutral amino acid transport GO:0015804 18 15 0,000 0,02299539 0,03962549 ! L-amino acid transport GO:0015807 16 15 0,000 0,02299539 0,03960678 ! microfilament motor activity GO:0000146 15 15 0,000 0,02299539 0,03958809 ! carbonate dehydratase activity GO:0004089 18 15 0,000 0,02299539 0,03956942 ! regulation of vasodilation GO:0042312 25 15 0,000 0,02299539 0,03955076 ! DNA replication initiation GO:0006270 15 15 0,000 0,02299539 0,03953212 ! taste receptor activity GO:0008527 15 15 0,000 0,02299539 0,0395135 ! cellular pigmentation GO:0033059 16 15 0,000 0,02299539 0,0394949 ! voltage-gated chloride channel activity GO:0005247 18 15 0,000 0,02299539 0,03947631 ! voltage-gated sodium channel activity GO:0005248 18 15 0,000 0,02299539 0,03945775 ! long-chain fatty acid transport GO:0015909 17 15 0,000 0,02299539 0,03943919 ! positive regulation of neurological system process GO:0031646 18 15 0,000 0,02299539 0,03942066 ! nerve-nerve synaptic transmission GO:0007270 17 15 0,000 0,02299539 0,03940215 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 17 15 0,000 0,02299539 0,03938365 ! ion gated channel activity GO:0022839 17 15 0,000 0,02299539 0,03936517 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 15 15 0,000 0,02299539 0,0393467 ! receptor activator activity GO:0030546 17 15 0,000 0,02299539 0,03932825 ! protein transmembrane transporter activity GO:0008320 16 15 0,000 0,02299539 0,03930983 ! negative regulation of mast cell proliferation GO:0070667 16 15 0,000 0,02299539 0,03929141 GO:0042130|negative regulation of T cell proliferation, ! acylglycerol O-acyltransferase activity GO:0016411 16 15 0,000 0,02299539 0,03927302 ! triacylglycerol lipase activity GO:0004806 16 15 0,000 0,02299539 0,03925464 ! peptide hormone processing GO:0016486 19 15 0,000 0,02299539 0,03923628 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,02299539 0,03921794 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 19 16 0,000 0,02451012 0,04178174 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,02451012 0,04176222 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 18 16 0,000 0,02451012 0,04174273 ! heterophilic cell adhesion GO:0007157 17 16 0,000 0,02451012 0,04172325 ! kinesin complex GO:0005871 16 16 0,000 0,02451012 0,04170379 ! negative regulation of gene expression, epigenetic GO:0045814 16 16 0,000 0,02451012 0,04168435 ! mitotic chromosome condensation GO:0007076 17 16 0,000 0,02451012 0,04166492 ! centrosome cycle GO:0007098 26 16 0,000 0,02451012 0,04164552 ! negative regulation of epithelial cell proliferation GO:0050680 18 16 0,000 0,02451012 0,04162613 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 16 0,000 0,02451012 0,04160676 ! DNA duplex unwinding GO:0032508 17 16 0,000 0,02451012 0,04158741 GO:0032392|DNA geometric change, ! cerebral cortex development GO:0021987 16 16 0,000 0,02451012 0,04156807 ! lysosomal transport GO:0007041 16 16 0,000 0,02451012 0,04154876 ! transforming growth factor beta receptor activity GO:0005024 18 16 0,000 0,02451012 0,04152946 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! rough endoplasmic reticulum GO:0005791 16 16 0,000 0,02451012 0,04151018 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 16 16 0,000 0,02451012 0,04149092 ! small nucleolar ribonucleoprotein complex GO:0005732 16 16 0,000 0,02451012 0,04147167 ! myofibril assembly GO:0030239 17 16 0,000 0,02451012 0,04145244 GO:0055002|striated muscle cell development, ! G1 phase GO:0051318 17 16 0,000 0,02451012 0,04143324 ! receptor signaling complex scaffold activity GO:0030159 19 16 0,000 0,02451012 0,04141405 ! negative regulation of inflammatory response GO:0050728 17 16 0,000 0,02451012 0,04139487 ! clathrin vesicle coat GO:0030125 20 16 0,000 0,02451012 0,04137572 ! endodeoxyribonuclease activity GO:0004520 43 16 0,000 0,02451012 0,04135658 ! sphingolipid catabolic process GO:0030149 18 16 0,000 0,02451012 0,04133746 GO:0046466|membrane lipid catabolic process, ! natural killer cell activation GO:0030101 17 16 0,000 0,02451012 0,04131836 ! steroid catabolic process GO:0006706 18 16 0,000 0,02451012 0,04129927 ! branched chain family amino acid metabolic process GO:0009081 18 16 0,000 0,02451012 0,0412802 ! cell-cell recognition GO:0009988 19 16 0,000 0,02451012 0,04126116 ! somatic diversification of immune receptors GO:0002200 17 16 0,000 0,02451012 0,04124212 ! spleen development GO:0048536 19 16 0,000 0,02451012 0,04122311 ! lymphocyte homeostasis GO:0002260 17 16 0,000 0,02451012 0,04120411 ! regulation of fatty acid oxidation GO:0046320 19 16 0,000 0,02451012 0,04118513 ! neural tube closure GO:0001843 19 16 0,000 0,02451012 0,04116617 GO:0060606|tube closure, ! antigen receptor-mediated signaling pathway GO:0050851 22 16 0,000 0,02451012 0,04114723 ! regulation of protein ubiquitination GO:0031396 27 16 0,000 0,02451012 0,0411283 ! regulation of glucose metabolic process GO:0010906 18 16 0,000 0,02451012 0,04110939 ! regulation of lipid catabolic process GO:0050994 18 16 0,000 0,02451012 0,0410905 ! viral genome replication GO:0019079 16 16 0,000 0,02451012 0,04107162 ! regulation of neurotransmitter transport GO:0051588 19 16 0,000 0,02451012 0,04105277 ! memory GO:0007613 18 16 0,000 0,02451012 0,04103393 ! regulation of carbohydrate biosynthetic process GO:0043255 17 16 0,000 0,02451012 0,0410151 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02451012 0,0409963 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 18 16 0,000 0,02451012 0,04097751 ! glycoprotein binding GO:0001948 19 16 0,000 0,02451012 0,04095874 ! negative regulation of endothelial cell proliferation GO:0001937 17 16 0,000 0,02451012 0,04093998 ! syntaxin binding GO:0019905 18 16 0,000 0,02451012 0,04092125 ! myosin binding GO:0017022 17 16 0,000 0,02451012 0,04090253 ! epidermis morphogenesis GO:0048730 18 16 0,000 0,02451012 0,04088382 ! fucose metabolic process GO:0006004 18 16 0,000 0,02451012 0,04086514 ! actin polymerization or depolymerization GO:0008154 18 16 0,000 0,02451012 0,04084647 ! preassembly of GPI anchor in ER membrane GO:0016254 18 16 0,000 0,02451012 0,04082782 ! intermediate filament cytoskeleton organization GO:0045104 16 16 0,000 0,02451012 0,04080918 ! behavioral interaction between organisms GO:0051705 19 16 0,000 0,02451012 0,04079057 ! nucleotide-excision repair, DNA gap filling GO:0006297 19 16 0,000 0,02451012 0,04077197 ! anchored to plasma membrane GO:0046658 20 16 0,000 0,02451012 0,04075338 ! calcium activated cation channel activity GO:0005227 18 16 0,000 0,02451012 0,04073482 ! DNA fragmentation involved in apoptosis GO:0006309 18 16 0,000 0,02451012 0,04071627 ! apoptotic protease activator activity GO:0016505 18 16 0,000 0,02451012 0,04069773 ! sulfuric ester hydrolase activity GO:0008484 18 16 0,000 0,02451012 0,04067922 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 18 16 0,000 0,02451012 0,04066072 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,02451012 0,04064224 ! RNA polymerase II transcription mediator activity GO:0016455 19 16 0,000 0,02451012 0,04062377 ! axoneme GO:0005930 16 16 0,000 0,02451012 0,04060532 ! negative regulation of homeostatic process GO:0032845 19 16 0,000 0,02451012 0,04058689 ! anion exchanger activity GO:0015380 17 17 0,000 0,02602259 0,04307187 ! positive regulation of hormone secretion GO:0046887 19 17 0,000 0,02602259 0,04305234 ! skin development GO:0043588 20 17 0,000 0,02602259 0,04303282 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 17 17 0,000 0,02602259 0,04301332 ! transcription from RNA polymerase III promoter GO:0006383 18 17 0,000 0,02602259 0,04299384 ! glial cell development GO:0021782 17 17 0,000 0,02602259 0,04297438 ! limbic system development GO:0021761 18 17 0,000 0,02602259 0,04295494 ! protein phosphatase type 2A regulator activity GO:0008601 19 17 0,000 0,02602259 0,04293551 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 17 0,000 0,02602259 0,0429161 ! ephrin receptor activity GO:0005003 21 17 0,000 0,02602259 0,0428967 ! acetylcholine receptor activity GO:0015464 18 17 0,000 0,02602259 0,04287733 ! glutamine metabolic process GO:0006541 26 17 0,000 0,02602259 0,04285797 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 21 17 0,000 0,02602259 0,04283863 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 37 17 0,000 0,02602259 0,04281931 ! signal sequence binding GO:0005048 18 17 0,000 0,02602259 0,0428 ! cell-substrate junction assembly GO:0007044 21 17 0,000 0,02602259 0,04278072 ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,02602259 0,04276144 ! organelle subcompartment GO:0031984 19 17 0,000 0,02602259 0,04274219 ! regulation of dephosphorylation GO:0035303 20 17 0,000 0,02602259 0,04272296 ! regulation of vasoconstriction GO:0019229 21 17 0,000 0,02602259 0,04270374 ! membrane depolarization GO:0051899 19 17 0,000 0,02602259 0,04268454 ! oogenesis GO:0048477 20 17 0,000 0,02602259 0,04266535 ! nuclear outer membrane GO:0005640 21 17 0,000 0,02602259 0,04264618 ! regulation of immunoglobulin mediated immune response GO:0002889 18 17 0,000 0,02602259 0,04262704 GO:0002712|regulation of B cell mediated immunity, ! immunoglobulin production GO:0002377 21 17 0,000 0,02602259 0,0426079 GO:0002440|production of molecular mediator of immune response, ! positive regulation of cellular carbohydrate metabolic process GO:0010676 18 17 0,000 0,02602259 0,04258879 ! positive regulation of macrophage differentiation GO:0045651 21 17 0,000 0,02602259 0,04256969 ! organic cation transport GO:0015695 17 17 0,000 0,02602259 0,04255061 ! porphyrin biosynthetic process GO:0006779 17 17 0,000 0,02602259 0,04253154 GO:0033014|tetrapyrrole biosynthetic process, ! phosphatidylinositol binding GO:0005545 21 17 0,000 0,02602259 0,0425125 ! hyaluronic acid binding GO:0005540 19 17 0,000 0,02602259 0,04249347 ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 17 0,000 0,02602259 0,04247446 ! negative regulation of coagulation GO:0050819 20 17 0,000 0,02602259 0,04245546 ! cellular monovalent inorganic cation homeostasis GO:0030004 18 17 0,000 0,02602259 0,04243648 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 17 0,000 0,02602259 0,04241752 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 17 0,000 0,02602259 0,04239857 ! negative regulation of defense response GO:0031348 19 17 0,000 0,02602259 0,04237965 ! lipid localization GO:0010876 19 17 0,000 0,02602259 0,04236074 GO:0019915|lipid storage, ! tube lumen formation GO:0035148 20 17 0,000 0,02602259 0,04234184 ! negative regulation of cytokine biosynthetic process GO:0042036 18 17 0,000 0,02602259 0,04232296 ! regulation of systemic arterial blood pressure by hormone GO:0001990 17 17 0,000 0,02602259 0,0423041 GO:0050886|endocrine process, ! MAP kinase kinase kinase activity GO:0004709 19 17 0,000 0,02602259 0,04228526 ! negative regulation of protein amino acid phosphorylation GO:0001933 19 17 0,000 0,02602259 0,04226643 ! protein phosphatase type 2A complex GO:0000159 21 17 0,000 0,02602259 0,04224762 ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 22 17 0,000 0,02602259 0,04222883 ! response to hexose stimulus GO:0009746 20 17 0,000 0,02602259 0,04221005 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! transmembrane receptor protein phosphatase activity GO:0019198 24 17 0,000 0,02602259 0,04219129 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 17 0,000 0,02602259 0,04217255 ! AMP binding GO:0016208 19 17 0,000 0,02602259 0,04215382 ! UDP-galactosyltransferase activity GO:0035250 19 17 0,000 0,02602259 0,04213511 ! receptor metabolic process GO:0043112 20 17 0,000 0,02602259 0,04211642 ! neurotransmitter metabolic process GO:0042133 20 17 0,000 0,02602259 0,04209774 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 23 17 0,000 0,02602259 0,04207908 ! alcohol binding GO:0043178 20 17 0,000 0,02602259 0,04206044 ! T cell differentiation in the thymus GO:0033077 28 17 0,000 0,02602259 0,04204181 ! visual learning GO:0008542 31 17 0,000 0,02602259 0,0420232 ! structural constituent of eye lens GO:0005212 20 17 0,000 0,02602259 0,04200461 ! cellular amino acid derivative catabolic process GO:0042219 19 17 0,000 0,02602259 0,04198603 ! neutrophil chemotaxis GO:0030593 17 17 0,000 0,02602259 0,04196747 ! protein localization in mitochondrion GO:0070585 19 17 0,000 0,02602259 0,04194892 GO:0006626|protein targeting to mitochondrion, ! aspartic-type endopeptidase activity GO:0004190 18 17 0,000 0,02602259 0,04193039 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 19 17 0,000 0,02602259 0,04191188 ! proton-transporting ATP synthase complex GO:0045259 17 17 0,000 0,02602259 0,04189338 ! translation elongation factor activity GO:0003746 19 17 0,000 0,02602259 0,0418749 ! histone binding GO:0042393 26 17 0,000 0,02602259 0,04185644 ! cilium assembly GO:0042384 18 17 0,000 0,02602259 0,04183799 ! transforming growth factor beta receptor binding GO:0005160 19 17 0,000 0,02602259 0,04181956 ! positive regulation of homeostatic process GO:0032846 23 17 0,000 0,02602259 0,04180115 ! solute:hydrogen antiporter activity GO:0015299 18 17 0,000 0,02602259 0,04178275 ! protein secretion GO:0009306 19 18 0,000 0,02753279 0,04418814 ! positive regulation of cell size GO:0045793 19 18 0,000 0,02753279 0,0441687 ! positive regulation of ossification GO:0045778 19 18 0,000 0,02753279 0,04414929 ! positive regulation of angiogenesis GO:0045766 19 18 0,000 0,02753279 0,04412989 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,02753279 0,04411051 GO:0005763|mitochondrial small ribosomal subunit, ! protein amino acid deacetylation GO:0006476 19 18 0,000 0,02753279 0,04409115 ! protein amino acid acetylation GO:0006473 21 18 0,000 0,02753279 0,0440718 ! positive regulation of nucleocytoplasmic transport GO:0046824 20 18 0,000 0,02753279 0,04405247 ! cAMP metabolic process GO:0046058 18 18 0,000 0,02753279 0,04403316 ! regulation of muscle cell differentiation GO:0051147 21 18 0,000 0,02753279 0,04401386 ! cornified envelope GO:0001533 22 18 0,000 0,02753279 0,04399458 ! retinoid metabolic process GO:0001523 19 18 0,000 0,02753279 0,04397532 GO:0016101|diterpenoid metabolic process, ! actomyosin GO:0042641 21 18 0,000 0,02753279 0,04395608 ! positive regulation of proteolysis GO:0045862 20 18 0,000 0,02753279 0,04393685 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 18 0,000 0,02753279 0,04391764 ! calcium-dependent protein binding GO:0048306 20 18 0,000 0,02753279 0,04389844 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 18 18 0,000 0,02753279 0,04387926 ! proton-transporting V-type ATPase complex GO:0033176 18 18 0,000 0,02753279 0,0438601 ! pyrimidine ribonucleoside metabolic process GO:0046131 23 18 0,000 0,02753279 0,04384096 ! regulation of ion transmembrane transporter activity GO:0032412 21 18 0,000 0,02753279 0,04382183 ! positive regulation of carbohydrate metabolic process GO:0045913 19 18 0,000 0,02753279 0,04380272 ! primary neural tube formation GO:0014020 21 18 0,000 0,02753279 0,04378362 ! recycling endosome GO:0055037 22 18 0,000 0,02753279 0,04376455 ! muscle cell development GO:0055001 20 18 0,000 0,02753279 0,04374548 ! kinase activator activity GO:0019209 22 18 0,000 0,02753279 0,04372644 ! positive regulation of T cell differentiation GO:0045582 28 18 0,000 0,02753279 0,04370741 ! cerebellum development GO:0021549 20 18 0,000 0,02753279 0,0436884 ! positive regulation of multicellular organism growth GO:0040018 19 18 0,000 0,02753279 0,04366941 ! somitogenesis GO:0001756 20 18 0,000 0,02753279 0,04365043 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,02753279 0,04363146 ! low-density lipoprotein binding GO:0030169 19 18 0,000 0,02753279 0,04361252 ! positive regulation of cytokine secretion GO:0050715 21 18 0,000 0,02753279 0,04359359 ! negative regulation of intracellular transport GO:0032387 20 18 0,000 0,02753279 0,04357468 ! glutamine family amino acid catabolic process GO:0009065 21 18 0,000 0,02753279 0,04355578 ! basal plasma membrane GO:0009925 21 18 0,000 0,02753279 0,0435369 GO:0045178|basal part of cell, ! vitamin D receptor binding GO:0042809 20 18 0,000 0,02753279 0,04351804 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 19 18 0,000 0,02753279 0,04349919 ! embryonic organ morphogenesis GO:0048562 22 18 0,000 0,02753279 0,04348036 ! negative regulation of translation GO:0017148 31 18 0,000 0,02753279 0,04346155 ! regulation of cell killing GO:0031341 24 18 0,000 0,02753279 0,04344275 ! positive regulation of cellular catabolic process GO:0031331 20 18 0,000 0,02753279 0,04342397 ! nuclear chromosome, telomeric region GO:0000784 30 18 0,000 0,02753279 0,0434052 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 19 18 0,000 0,02753279 0,04338645 ! intra-Golgi vesicle-mediated transport GO:0006891 20 18 0,000 0,02753279 0,04336772 ! protein complex scaffold GO:0032947 22 18 0,000 0,02753279 0,043349 ! SNAP receptor activity GO:0005484 21 18 0,000 0,02753279 0,0433303 ! dendrite development GO:0016358 22 18 0,000 0,02753279 0,04331161 ! cell differentiation in spinal cord GO:0021515 21 18 0,000 0,02753279 0,04329294 ! inactivation of MAPK activity GO:0000188 20 18 0,000 0,02753279 0,04327429 ! calmodulin-dependent protein kinase activity GO:0004683 20 18 0,000 0,02753279 0,04325566 ! D-ribose metabolic process GO:0006014 19 18 0,000 0,02753279 0,04323703 ! nuclear ubiquitin ligase complex GO:0000152 31 18 0,000 0,02753279 0,04321843 ! glucuronosyltransferase activity GO:0015020 18 18 0,000 0,02753279 0,04319984 ! coreceptor activity GO:0015026 28 18 0,000 0,02753279 0,04318127 ! response to fungus GO:0009620 18 18 0,000 0,02753279 0,04316271 ! stem cell differentiation GO:0048863 18 18 0,000 0,02753279 0,04314417 ! intermediate filament-based process GO:0045103 18 18 0,000 0,02753279 0,04312565 ! heart process GO:0003015 19 18 0,000 0,02753279 0,04310714 GO:0060047|heart contraction, ! mismatch repair GO:0006298 28 18 0,000 0,02753279 0,04308865 ! vasodilation GO:0042311 20 18 0,000 0,02753279 0,04307017 ! transport vesicle membrane GO:0030658 23 18 0,000 0,02753279 0,04305171 ! MHC protein binding GO:0042287 30 18 0,000 0,02753279 0,04303326 ! inward rectifier potassium channel activity GO:0005242 22 18 0,000 0,02753279 0,04301483 ! chloride transmembrane transporter activity GO:0015108 19 18 0,000 0,02753279 0,04299642 ! bicarbonate transmembrane transporter activity GO:0015106 18 18 0,000 0,02753279 0,04297802 ! ionotropic glutamate receptor activity GO:0004970 22 18 0,000 0,02753279 0,04295964 ! cell-cell adherens junction GO:0005913 20 18 0,000 0,02753279 0,04294127 ! negative regulation of leukocyte proliferation GO:0070664 20 18 0,000 0,02753279 0,04292292 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! ubiquitin-specific protease activity GO:0004843 19 18 0,000 0,02753279 0,04290458 ! ATP-dependent RNA helicase activity GO:0004004 28 18 0,000 0,02753279 0,04288626 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 24 19 0,000 0,02904074 0,0452158 ! pteridine and derivative metabolic process GO:0042558 29 19 0,000 0,02904074 0,04519651 ! proteasome core complex GO:0005839 20 19 0,000 0,02904074 0,04517723 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 22 19 0,000 0,02904074 0,04515797 ! anion:anion antiporter activity GO:0015301 19 19 0,000 0,02904074 0,04513873 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 24 19 0,000 0,02904074 0,04511951 ! regulation of transmembrane transporter activity GO:0022898 22 19 0,000 0,02904074 0,0451003 GO:0032409|regulation of transporter activity, ! regulation of survival gene product expression GO:0045884 23 19 0,000 0,02904074 0,04508111 ! activation of pro-apoptotic gene products GO:0008633 26 19 0,000 0,02904074 0,04506193 ! deoxyribonucleotide metabolic process GO:0009262 20 19 0,000 0,02904074 0,04504278 ! lysosome organization GO:0007040 20 19 0,000 0,02904074 0,04502363 ! cellular macromolecular complex disassembly GO:0034623 23 19 0,000 0,02904074 0,04500451 ! central nervous system neuron development GO:0021954 21 19 0,000 0,02904074 0,0449854 ! threonine-type endopeptidase activity GO:0004298 20 19 0,000 0,02904074 0,0449663 GO:0070003|threonine-type peptidase activity, ! chromosome condensation GO:0030261 20 19 0,000 0,02904074 0,04494722 ! peptidyl-serine phosphorylation GO:0018105 26 19 0,000 0,02904074 0,04492816 ! regulation of endothelial cell migration GO:0010594 22 19 0,000 0,02904074 0,04490912 ! fatty acid beta-oxidation GO:0006635 21 19 0,000 0,02904074 0,04489009 ! peptide cross-linking GO:0018149 23 19 0,000 0,02904074 0,04487107 ! ventricular cardiac muscle morphogenesis GO:0055010 21 19 0,000 0,02904074 0,04485208 ! beta-catenin binding GO:0008013 23 19 0,000 0,02904074 0,0448331 ! positive regulation of locomotion GO:0040017 21 19 0,000 0,02904074 0,04481413 GO:0050921|positive regulation of chemotaxis, ! cell projection membrane GO:0031253 21 19 0,000 0,02904074 0,04479518 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,02904074 0,04477625 ! trans-Golgi network transport vesicle GO:0030140 26 19 0,000 0,02904074 0,04475733 ! sphingolipid biosynthetic process GO:0030148 20 19 0,000 0,02904074 0,04473843 ! vitamin transport GO:0051180 21 19 0,000 0,02904074 0,04471955 ! positive regulation of osteoblast differentiation GO:0045669 22 19 0,000 0,02904074 0,04470068 ! terpenoid metabolic process GO:0006721 20 19 0,000 0,02904074 0,04468183 ! leukotriene biosynthetic process GO:0019370 20 19 0,000 0,02904074 0,04466299 GO:0043450|alkene biosynthetic process, ! nerve development GO:0021675 24 19 0,000 0,02904074 0,04464417 ! retinoid binding GO:0005501 19 19 0,000 0,02904074 0,04462536 GO:0019840|isoprenoid binding, ! regulation of amine transport GO:0051952 23 19 0,000 0,02904074 0,04460657 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 22 19 0,000 0,02904074 0,0445878 ! histone deacetylase activity GO:0004407 20 19 0,000 0,02904074 0,04456904 GO:0033558|protein deacetylase activity, ! regulation of microtubule polymerization or depolymerization GO:0031110 21 19 0,000 0,02904074 0,0445503 ! gluconeogenesis GO:0006094 23 19 0,000 0,02904074 0,04453157 ! post-Golgi vesicle-mediated transport GO:0006892 23 19 0,000 0,02904074 0,04451286 ! microtubule-based transport GO:0010970 20 19 0,000 0,02904074 0,04449417 ! superoxide metabolic process GO:0006801 21 19 0,000 0,02904074 0,04447549 ! C21-steroid hormone metabolic process GO:0008207 20 19 0,000 0,02904074 0,04445682 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,02904074 0,04443817 GO:0006479|protein amino acid methylation, ! L-ascorbic acid binding GO:0031418 19 19 0,000 0,02904074 0,04441954 ! regulation of DNA recombination GO:0000018 38 19 0,000 0,02904074 0,04440093 ! photoreceptor cell maintenance GO:0045494 23 19 0,000 0,02904074 0,04438232 ! positive regulation of cytoskeleton organization GO:0051495 22 19 0,000 0,02904074 0,04436374 ! acetylcholine binding GO:0042166 20 19 0,000 0,02904074 0,04434517 ! heme metabolic process GO:0042168 20 19 0,000 0,02904074 0,04432661 ! SH2 domain binding GO:0042169 25 19 0,000 0,02904074 0,04430808 ! neurotransmitter:sodium symporter activity GO:0005328 21 19 0,000 0,02904074 0,04428955 ! negative regulation of protein catabolic process GO:0042177 19 19 0,000 0,02904074 0,04427104 ! carbohydrate kinase activity GO:0019200 20 19 0,000 0,02904074 0,04425255 ! RNA methyltransferase activity GO:0008173 19 19 0,000 0,02904074 0,04423407 ! RNA-dependent ATPase activity GO:0008186 29 19 0,000 0,02904074 0,04421561 ! body fluid secretion GO:0007589 21 19 0,000 0,02904074 0,04419717 ! neuropeptide hormone activity GO:0005184 25 19 0,000 0,02904074 0,04417874 ! secretory granule membrane GO:0030667 21 19 0,000 0,02904074 0,04416032 ! extracellular-glutamate-gated ion channel activity GO:0005234 23 19 0,000 0,02904074 0,04414192 ! ribonucleoprotein binding GO:0043021 20 19 0,000 0,02904074 0,04412354 ! peptidase activator activity GO:0016504 21 19 0,000 0,02904074 0,04410517 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,02904074 0,04408681 ! small conjugating protein-specific protease activity GO:0019783 21 19 0,000 0,02904074 0,04406847 ! regulation of BMP signaling pathway GO:0030510 20 19 0,000 0,02904074 0,04405015 ! sialyltransferase activity GO:0008373 31 19 0,000 0,02904074 0,04403184 ! ATP-dependent DNA helicase activity GO:0004003 30 19 0,000 0,02904074 0,04401355 ! chaperone binding GO:0051087 21 20 0,000 0,03054642 0,04627631 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 23 20 0,000 0,03054642 0,0462571 ! regulation of anti-apoptosis GO:0045767 20 20 0,000 0,03054642 0,0462379 ! reciprocal meiotic recombination GO:0007131 40 20 0,000 0,03054642 0,04621873 ! protein amino acid ADP-ribosylation GO:0006471 23 20 0,000 0,03054642 0,04619956 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 30 20 0,000 0,03054642 0,04618042 ! retina development in camera-type eye GO:0060041 24 20 0,000 0,03054642 0,04616129 ! negative regulation of lipid metabolic process GO:0045833 34 20 0,000 0,03054642 0,04614217 ! ovarian follicle development GO:0001541 21 20 0,000 0,03054642 0,04612307 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 33 20 0,000 0,03054642 0,04610399 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 21 20 0,000 0,03054642 0,04608492 ! hydrogen peroxide metabolic process GO:0042743 20 20 0,000 0,03054642 0,04606587 ! diencephalon development GO:0021536 22 20 0,000 0,03054642 0,04604684 ! nuclear inner membrane GO:0005637 21 20 0,000 0,03054642 0,04602782 ! regulation of lipid transport GO:0032368 22 20 0,000 0,03054642 0,04600881 ! response to glucocorticoid stimulus GO:0051384 22 20 0,000 0,03054642 0,04598983 ! glutathione metabolic process GO:0006749 21 20 0,000 0,03054642 0,04597085 ! transcriptional repressor complex GO:0017053 23 20 0,000 0,03054642 0,0459519 ! vitamin A metabolic process GO:0006776 20 20 0,000 0,03054642 0,04593295 ! positive regulation of lymphocyte differentiation GO:0045621 30 20 0,000 0,03054642 0,04591403 ! negative regulation of cytokine production GO:0001818 23 20 0,000 0,03054642 0,04589512 ! phosphorus-oxygen lyase activity GO:0016849 21 20 0,000 0,03054642 0,04587622 ! peptide hormone secretion GO:0030072 25 20 0,000 0,03054642 0,04585734 GO:0002790|peptide secretion, ! actin filament-based movement GO:0030048 22 20 0,000 0,03054642 0,04583848 ! Rab GTPase binding GO:0017137 22 20 0,000 0,03054642 0,04581963 ! initiation of viral infection GO:0019059 22 20 0,000 0,03054642 0,0458008 ! voltage-gated anion channel activity GO:0008308 23 20 0,000 0,03054642 0,04578198 ! heterochromatin GO:0000792 20 20 0,000 0,03054642 0,04576318 ! aminoglycan catabolic process GO:0006026 22 20 0,000 0,03054642 0,0457444 ! glycosaminoglycan biosynthetic process GO:0006024 21 20 0,000 0,03054642 0,04572562 ! regulation of chemotaxis GO:0050920 22 20 0,000 0,03054642 0,04570687 ! calcium-independent cell-cell adhesion GO:0016338 27 20 0,000 0,03054642 0,04568813 ! high-density lipoprotein particle GO:0034364 30 20 0,000 0,03054642 0,0456694 ! visual behavior GO:0007632 34 20 0,000 0,03054642 0,0456507 ! regulation of cell-matrix adhesion GO:0001952 26 20 0,000 0,03054642 0,045632 GO:0010810|regulation of cell-substrate adhesion, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 23 20 0,000 0,03054642 0,04561332 ! immune response-activating cell surface receptor signaling pathway GO:0002429 27 20 0,000 0,03054642 0,04559466 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of nitric oxide biosynthetic process GO:0045428 21 20 0,000 0,03054642 0,04557601 ! vesicle docking during exocytosis GO:0006904 21 20 0,000 0,03054642 0,04555738 ! cell structure disassembly during apoptosis GO:0006921 31 20 0,000 0,03054642 0,04553876 ! nucleotide kinase activity GO:0019201 26 20 0,000 0,03054642 0,04552016 ! rRNA binding GO:0019843 22 20 0,000 0,03054642 0,04550157 ! cytolysis GO:0019835 22 20 0,000 0,03054642 0,045483 ! renal system process GO:0003014 22 20 0,000 0,03054642 0,04546444 ! specific transcriptional repressor activity GO:0016566 23 20 0,000 0,03054642 0,0454459 ! fatty acid transport GO:0015908 23 20 0,000 0,03054642 0,04542737 ! transaminase activity GO:0008483 22 20 0,000 0,03054642 0,04540886 ! activation of JUN kinase activity GO:0007257 22 20 0,000 0,03054642 0,04539037 ! collagen catabolic process GO:0030574 21 20 0,000 0,03054642 0,04537188 ! microvillus GO:0005902 25 20 0,000 0,03054642 0,04535342 ! tumor necrosis factor receptor binding GO:0005164 22 20 0,000 0,03054642 0,04533497 ! connexon complex GO:0005922 23 20 0,000 0,03054642 0,04531653 ! positive regulation of DNA replication GO:0045740 27 21 0,000 0,03204985 0,04752759 ! positive regulation of protein catabolic process GO:0045732 23 21 0,000 0,03204985 0,04750827 ! translational initiation GO:0006413 21 21 0,000 0,03204985 0,04748898 ! NF-kappaB binding GO:0051059 31 21 0,000 0,03204985 0,0474697 ! heterotrimeric G-protein complex GO:0005834 23 21 0,000 0,03204985 0,04745043 ! positive regulation of bone remodeling GO:0046852 22 21 0,000 0,03204985 0,04743118 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 21 0,000 0,03204985 0,04741195 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! transition metal ion transmembrane transporter activity GO:0046915 25 21 0,000 0,03204985 0,04739273 ! glutathione transferase activity GO:0004364 21 21 0,000 0,03204985 0,04737353 ! voltage-gated calcium channel complex GO:0005891 28 21 0,000 0,03204985 0,04735434 ! glutamate signaling pathway GO:0007215 23 21 0,000 0,03204985 0,04733517 ! regeneration GO:0031099 24 21 0,000 0,03204985 0,04731601 ! apoptotic mitochondrial changes GO:0008637 33 21 0,000 0,03204985 0,04729687 ! MHC class I protein complex GO:0042612 31 21 0,000 0,03204985 0,04727774 ! cellular response to starvation GO:0009267 22 21 0,000 0,03204985 0,04725863 ! peroxisome organization GO:0007031 22 21 0,000 0,03204985 0,04723954 ! vacuole organization GO:0007033 23 21 0,000 0,03204985 0,04722046 ! apoptotic nuclear changes GO:0030262 24 21 0,000 0,03204985 0,0472014 ! response to lipopolysaccharide GO:0032496 31 21 0,000 0,03204985 0,04718235 ! neural crest cell development GO:0014032 24 21 0,000 0,03204985 0,04716332 GO:0014033|neural crest cell differentiation, ! regulation of protein binding GO:0043393 25 21 0,000 0,03204985 0,0471443 ! nucleobase metabolic process GO:0009112 23 21 0,000 0,03204985 0,0471253 ! regulation of steroid metabolic process GO:0019218 23 21 0,000 0,03204985 0,04710631 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,03204985 0,04708734 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! monocarboxylic acid transmembrane transporter activity GO:0008028 25 21 0,000 0,03204985 0,04706838 ! pallium development GO:0021543 22 21 0,000 0,03204985 0,04704944 ! synaptic vesicle transport GO:0048489 25 21 0,000 0,03204985 0,04703052 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 21 0,000 0,03204985 0,04701161 ! leukocyte homeostasis GO:0001776 22 21 0,000 0,03204985 0,04699271 ! negative regulation of neuron differentiation GO:0045665 22 21 0,000 0,03204985 0,04697383 ! cyclase activity GO:0009975 22 21 0,000 0,03204985 0,04695496 ! aspartate family amino acid metabolic process GO:0009066 24 21 0,000 0,03204985 0,04693611 ! gut development GO:0048565 23 21 0,000 0,03204985 0,04691728 ! calcium-dependent phospholipid binding GO:0005544 22 21 0,000 0,03204985 0,04689846 ! negative regulation of T cell activation GO:0050868 23 21 0,000 0,03204985 0,04687966 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,03204985 0,04686087 ! cortical actin cytoskeleton GO:0030864 21 21 0,000 0,03204985 0,04684209 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,03204985 0,04682333 ! membrane lipid biosynthetic process GO:0046467 22 21 0,000 0,03204985 0,04680459 ! nucleotide-excision repair, DNA damage removal GO:0000718 22 21 0,000 0,03204985 0,04678586 ! axis specification GO:0009798 25 21 0,000 0,03204985 0,04676714 ! response to alkaloid GO:0043279 27 21 0,000 0,03204985 0,04674845 ! response to ethanol GO:0045471 28 21 0,000 0,03204985 0,04672976 ! response to carbohydrate stimulus GO:0009743 24 21 0,000 0,03204985 0,04671109 ! smooth muscle contraction GO:0006939 25 21 0,000 0,03204985 0,04669244 ! ubiquitin binding GO:0043130 25 21 0,000 0,03204985 0,0466738 ! vesicle targeting GO:0006903 22 21 0,000 0,03204985 0,04665517 ! phospholipase A2 activity GO:0004623 32 21 0,000 0,03204985 0,04663656 ! SNARE binding GO:0000149 24 21 0,000 0,03204985 0,04661797 ! interaction with host GO:0051701 26 21 0,000 0,03204985 0,04659939 ! positive regulation of myeloid leukocyte differentiation GO:0002763 26 21 0,000 0,03204985 0,04658082 ! lymphocyte proliferation GO:0046651 24 21 0,000 0,03204985 0,04656227 ! regulation of tumor necrosis factor production GO:0032680 24 21 0,000 0,03204985 0,04654374 ! regulation of interleukin-2 production GO:0032663 21 21 0,000 0,03204985 0,04652521 ! negative regulation of angiogenesis GO:0016525 23 21 0,000 0,03204985 0,04650671 ! single-stranded RNA binding GO:0003727 22 21 0,000 0,03204985 0,04648822 ! cyclic nucleotide binding GO:0030551 25 21 0,000 0,03204985 0,04646974 ! caveola GO:0005901 25 21 0,000 0,03204985 0,04645128 ! water-soluble vitamin biosynthetic process GO:0042364 23 21 0,000 0,03204985 0,04643283 ! insulin receptor binding GO:0005158 25 21 0,000 0,03204985 0,0464144 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,03204985 0,04639598 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,03204985 0,04637757 ! mRNA export from nucleus GO:0006406 26 22 0,000 0,03355103 0,0485306 ! metencephalon development GO:0022037 25 22 0,000 0,03355103 0,04851136 ! regulation of interferon-gamma production GO:0032649 25 22 0,000 0,03355103 0,04849214 ! hormone secretion GO:0046879 28 22 0,000 0,03355103 0,04847294 ! vesicle docking GO:0048278 24 22 0,000 0,03355103 0,04845375 ! muscle myosin complex GO:0005859 23 22 0,000 0,03355103 0,04843457 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 24 22 0,000 0,03355103 0,04841541 ! actomyosin structure organization GO:0031032 24 22 0,000 0,03355103 0,04839627 ! microtubule organizing center organization GO:0031023 33 22 0,000 0,03355103 0,04837714 GO:0051297|centrosome organization, ! positive regulation of innate immune response GO:0045089 23 22 0,000 0,03355103 0,04835803 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 33 22 0,000 0,03355103 0,04833893 ! sperm motility GO:0030317 23 22 0,000 0,03355103 0,04831984 ! potassium channel regulator activity GO:0015459 29 22 0,000 0,03355103 0,04830078 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 24 22 0,000 0,03355103 0,04828172 ! vacuolar transport GO:0007034 22 22 0,000 0,03355103 0,04826268 ! oxidoreductase activity, acting on heme group of donors GO:0016675 23 22 0,000 0,03355103 0,04824366 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! central nervous system neuron differentiation GO:0021953 24 22 0,000 0,03355103 0,04822465 ! cellular response to reactive oxygen species GO:0034614 26 22 0,000 0,03355103 0,04820566 ! purine ribonucleoside metabolic process GO:0046128 24 22 0,000 0,03355103 0,04818668 GO:0042278|purine nucleoside metabolic process, ! G-protein chemoattractant receptor activity GO:0001637 24 22 0,000 0,03355103 0,04816772 GO:0004950|chemokine receptor activity, ! response to corticosteroid stimulus GO:0031960 25 22 0,000 0,03355103 0,04814877 ! PML body GO:0016605 25 22 0,000 0,03355103 0,04812983 ! barbed-end actin filament capping GO:0051016 24 22 0,000 0,03355103 0,04811091 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 27 22 0,000 0,03355103 0,04809201 ! regulation of foam cell differentiation GO:0010743 28 22 0,000 0,03355103 0,04807312 ! cyclic nucleotide biosynthetic process GO:0009190 23 22 0,000 0,03355103 0,04805425 ! leukotriene metabolic process GO:0006691 23 22 0,000 0,03355103 0,04803539 ! glycosphingolipid metabolic process GO:0006687 23 22 0,000 0,03355103 0,04801654 ! deacetylase activity GO:0019213 23 22 0,000 0,03355103 0,04799771 ! pentose metabolic process GO:0019321 23 22 0,000 0,03355103 0,0479789 ! collagen fibril organization GO:0030199 32 22 0,000 0,03355103 0,0479601 ! regulation of response to biotic stimulus GO:0002831 33 22 0,000 0,03355103 0,04794131 ! positive regulation of adaptive immune response GO:0002821 22 22 0,000 0,03355103 0,04792254 ! peptidyl-serine modification GO:0018209 30 22 0,000 0,03355103 0,04790378 ! DNA-directed RNA polymerase complex GO:0000428 23 22 0,000 0,03355103 0,04788504 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 32 22 0,000 0,03355103 0,04786631 ! positive regulation of behavior GO:0048520 24 22 0,000 0,03355103 0,0478476 ! regulation of generation of precursor metabolites and energy GO:0043467 25 22 0,000 0,03355103 0,0478289 ! aromatic compound catabolic process GO:0019439 23 22 0,000 0,03355103 0,04781022 ! embryonic epithelial tube formation GO:0001838 25 22 0,000 0,03355103 0,04779155 GO:0001841|neural tube formation, ! telomere organization GO:0032200 43 22 0,000 0,03355103 0,0477729 GO:0000723|telomere maintenance, ! acetyl-CoA catabolic process GO:0046356 24 22 0,000 0,03355103 0,04775426 GO:0006099|tricarboxylic acid cycle, ! protein tetramerization GO:0051262 25 22 0,000 0,03355103 0,04773563 ! DNA catabolic process, endonucleolytic GO:0000737 24 22 0,000 0,03355103 0,04771702 ! glycerol metabolic process GO:0006071 24 22 0,000 0,03355103 0,04769843 ! cellular component assembly involved in morphogenesis GO:0010927 23 22 0,000 0,03355103 0,04767985 ! nuclear chromatin GO:0000790 23 22 0,000 0,03355103 0,04766128 ! cellular iron ion homeostasis GO:0006879 25 22 0,000 0,03355103 0,04764273 ! aminoglycan biosynthetic process GO:0006023 23 22 0,000 0,03355103 0,04762419 ! positive regulation of JAK-STAT cascade GO:0046427 25 22 0,000 0,03355103 0,04760567 ! sterol binding GO:0032934 24 22 0,000 0,03355103 0,04758716 ! calcium-dependent cell-cell adhesion GO:0016339 23 22 0,000 0,03355103 0,04756866 ! digestive system process GO:0022600 25 22 0,000 0,03355103 0,04755018 ! neurotransmitter transporter activity GO:0005326 24 22 0,000 0,03355103 0,04753171 ! organic acid:sodium symporter activity GO:0005343 25 22 0,000 0,03355103 0,04751326 ! nonmotile primary cilium GO:0031513 24 22 0,000 0,03355103 0,04749483 ! negative regulation of myeloid leukocyte differentiation GO:0002762 26 22 0,000 0,03355103 0,0474764 ! base-excision repair GO:0006284 33 22 0,000 0,03355103 0,04745799 ! regulation of chromosome organization GO:0033044 27 22 0,000 0,03355103 0,0474396 ! DNA modification GO:0006304 25 22 0,000 0,03355103 0,04742122 ! detection of chemical stimulus GO:0009593 23 22 0,000 0,03355103 0,04740285 ! positive regulation of tissue remodeling GO:0034105 23 22 0,000 0,03355103 0,0473845 ! GABA-A receptor activity GO:0004890 27 22 0,000 0,03355103 0,04736616 ! response to cytokine stimulus GO:0034097 25 22 0,000 0,03355103 0,04734784 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 24 22 0,000 0,03355103 0,04732953 ! pyrimidine nucleoside metabolic process GO:0006213 27 22 0,000 0,03355103 0,04731124 ! phosphoprotein phosphatase inhibitor activity GO:0004864 25 22 0,000 0,03355103 0,04729295 ! solute:cation antiporter activity GO:0015298 23 22 0,000 0,03355103 0,04727469 ! regulation of transmembrane transport GO:0034762 28 23 0,000 0,03504996 0,04936767 ! protein amino acid O-linked glycosylation GO:0006493 28 23 0,000 0,03504996 0,04934862 ! leukocyte adhesion GO:0007159 26 23 0,000 0,03504996 0,04932958 ! dicarboxylic acid metabolic process GO:0043648 27 23 0,000 0,03504996 0,04931055 ! odontogenesis of dentine-containing tooth GO:0042475 26 23 0,000 0,03504996 0,04929154 ! positive regulation of endocytosis GO:0045807 25 23 0,000 0,03504996 0,04927255 ! mitochondrial membrane organization GO:0007006 25 23 0,000 0,03504996 0,04925357 ! ureteric bud development GO:0001657 24 23 0,000 0,03504996 0,0492346 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 27 23 0,000 0,03504996 0,04921565 ! regulation of insulin secretion GO:0050796 27 23 0,000 0,03504996 0,04919672 ! vitamin biosynthetic process GO:0009110 25 23 0,000 0,03504996 0,04917779 ! negative regulation of neurogenesis GO:0050768 29 23 0,000 0,03504996 0,04915889 ! cholesterol biosynthetic process GO:0006695 29 23 0,000 0,03504996 0,04913999 ! deaminase activity GO:0019239 24 23 0,000 0,03504996 0,04912112 ! sensory perception of pain GO:0019233 26 23 0,000 0,03504996 0,04910225 ! lipid kinase activity GO:0001727 26 23 0,000 0,03504996 0,0490834 ! platelet activation GO:0030168 27 23 0,000 0,03504996 0,04906457 ! proteoglycan biosynthetic process GO:0030166 24 23 0,000 0,03504996 0,04904575 ! positive regulation of intracellular transport GO:0032388 26 23 0,000 0,03504996 0,04902694 ! regulation of blood coagulation GO:0030193 26 23 0,000 0,03504996 0,04900815 ! regulation of cytokine secretion GO:0050707 27 23 0,000 0,03504996 0,04898937 ! fat-soluble vitamin metabolic process GO:0006775 23 23 0,000 0,03504996 0,04897061 ! cellular alkene metabolic process GO:0043449 24 23 0,000 0,03504996 0,04895186 ! aromatic amino acid family metabolic process GO:0009072 25 23 0,000 0,03504996 0,04893313 ! cell surface binding GO:0043498 28 23 0,000 0,03504996 0,04891441 ! porphyrin metabolic process GO:0006778 24 23 0,000 0,03504996 0,0488957 GO:0033013|tetrapyrrole metabolic process, ! ligase activity, forming carbon-sulfur bonds GO:0016877 24 23 0,000 0,03504996 0,04887701 ! regulation of glucose import GO:0046324 28 23 0,000 0,03504996 0,04885834 ! insulin-like growth factor binding GO:0005520 27 23 0,000 0,03504996 0,04883967 ! alditol metabolic process GO:0019400 25 23 0,000 0,03504996 0,04882103 ! positive regulation of JUN kinase activity GO:0043507 25 23 0,000 0,03504996 0,04880239 ! pyruvate metabolic process GO:0006090 27 23 0,000 0,03504996 0,04878377 ! zinc ion transport GO:0006829 26 23 0,000 0,03504996 0,04876517 ! N-acetylglucosamine metabolic process GO:0006044 26 23 0,000 0,03504996 0,04874658 ! antigen processing and presentation of peptide antigen GO:0048002 30 23 0,000 0,03504996 0,048728 ! sex determination GO:0007530 25 23 0,000 0,03504996 0,04870944 ! phosphate binding GO:0042301 25 23 0,000 0,03504996 0,04869089 ! positive regulation of leukocyte mediated immunity GO:0002705 24 23 0,000 0,03504996 0,04867235 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of interleukin-6 production GO:0032675 26 23 0,000 0,03504996 0,04865383 ! nuclear-transcribed mRNA catabolic process GO:0000956 26 23 0,000 0,03504996 0,04863532 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 28 23 0,000 0,03504996 0,04861683 ! ubiquitin protein ligase binding GO:0031625 24 23 0,000 0,03504996 0,04859835 ! positive regulation of nuclear division GO:0051785 35 23 0,000 0,03504996 0,04857989 GO:0045840|positive regulation of mitosis, ! synaptogenesis GO:0007416 25 23 0,000 0,03504996 0,04856144 ! regulation of bone mineralization GO:0030500 23 23 0,000 0,03504996 0,048543 ! neurotransmitter secretion GO:0007269 26 23 0,000 0,03504996 0,04852458 ! ethanolamine and derivative metabolic process GO:0042439 34 23 0,000 0,03504996 0,04850617 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 25 23 0,000 0,03504996 0,04848778 ! leukocyte proliferation GO:0070661 26 23 0,000 0,03504996 0,0484694 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 24 23 0,000 0,03504996 0,04845103 ! oligosaccharide metabolic process GO:0009311 29 24 0,000 0,03654665 0,05050083 ! actin filament GO:0005884 26 24 0,000 0,03654665 0,0504817 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,03654665 0,0504626 ! pancreas development GO:0031016 27 24 0,000 0,03654665 0,0504435 ! androgen receptor binding GO:0050681 34 24 0,000 0,03654665 0,05042443 ! calcium channel complex GO:0034704 31 24 0,000 0,03654665 0,05040536 ! coenzyme catabolic process GO:0009109 26 24 0,000 0,03654665 0,05038631 ! negative regulation of cell development GO:0010721 30 24 0,000 0,03654665 0,05036728 ! cardiac muscle tissue morphogenesis GO:0055008 27 24 0,000 0,03654665 0,05034826 GO:0060415|muscle tissue morphogenesis, ! phosphatase inhibitor activity GO:0019212 27 24 0,000 0,03654665 0,05032925 ! regulation of ARF GTPase activity GO:0032312 28 24 0,000 0,03654665 0,05031026 ! regulation of oxidoreductase activity GO:0051341 24 24 0,000 0,03654665 0,05029128 ! RNA splicing factor activity, transesterification mechanism GO:0031202 25 24 0,000 0,03654665 0,05027232 ! Rho GTPase binding GO:0017048 36 24 0,000 0,03654665 0,05025337 ! regulation of glucose transport GO:0010827 29 24 0,000 0,03654665 0,05023443 ! serine family amino acid metabolic process GO:0009069 27 24 0,000 0,03654665 0,05021551 ! intramolecular transferase activity GO:0016866 26 24 0,000 0,03654665 0,0501966 ! phosphoinositide phospholipase C activity GO:0004435 28 24 0,000 0,03654665 0,05017771 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! Z disc GO:0030018 27 24 0,000 0,03654665 0,05015883 ! protein stabilization GO:0050821 24 24 0,000 0,03654665 0,05013997 ! protein import into nucleus, translocation GO:0000060 27 24 0,000 0,03654665 0,05012112 ! embryonic pattern specification GO:0009880 29 24 0,000 0,03654665 0,05010228 ! negative regulation of actin filament depolymerization GO:0030835 26 24 0,000 0,03654665 0,05008346 ! RNA polymerase complex GO:0030880 25 24 0,000 0,03654665 0,05006466 ! cellular polysaccharide biosynthetic process GO:0033692 24 24 0,000 0,03654665 0,05004586 ! glucosamine metabolic process GO:0006041 27 24 0,000 0,03654665 0,05002708 ! small conjugating protein binding GO:0032182 29 24 0,000 0,03654665 0,05000832 ! regulation of transcription factor import into nucleus GO:0042990 26 24 0,000 0,03654665 0,04998957 ! chemokine binding GO:0019956 26 24 0,000 0,03654665 0,04997083 ! catechol metabolic process GO:0009712 29 24 0,000 0,03654665 0,04995211 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of smooth muscle contraction GO:0006940 28 24 0,000 0,03654665 0,0499334 ! NAD+ ADP-ribosyltransferase activity GO:0003950 26 24 0,000 0,03654665 0,04991471 ! multicellular organismal response to stress GO:0033555 27 24 0,000 0,03654665 0,04989603 ! cell aging GO:0007569 47 24 0,000 0,03654665 0,04987736 ! immune response-activating signal transduction GO:0002757 31 24 0,000 0,03654665 0,04985871 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 24 0,000 0,03654665 0,04984007 ! fibroblast growth factor receptor signaling pathway GO:0008543 27 24 0,000 0,03654665 0,04982144 ! voltage-gated calcium channel activity GO:0005245 31 24 0,000 0,03654665 0,04980283 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 29 24 0,000 0,03654665 0,04978423 ! metallocarboxypeptidase activity GO:0004181 24 24 0,000 0,03654665 0,04976565 ! caspase regulator activity GO:0043028 26 24 0,000 0,03654665 0,04974708 ! regulation of microtubule cytoskeleton organization GO:0070507 35 24 0,000 0,03654665 0,04972853 ! 3'-5' exonuclease activity GO:0008408 43 24 0,000 0,03654665 0,04970999 ! small nuclear ribonucleoprotein complex GO:0030532 24 24 0,000 0,03654665 0,04969146 ! selenium binding GO:0008430 24 24 0,000 0,03654665 0,04967294 ! spindle pole GO:0000922 35 24 0,000 0,03654665 0,04965444 ! Rho GTPase activator activity GO:0005100 28 24 0,000 0,03654665 0,04963596 ! phenol metabolic process GO:0018958 31 25 0,000 0,0380411 0,05164641 ! regulation of lipid biosynthetic process GO:0046890 35 25 0,000 0,0380411 0,0516272 ! protein amino acid acylation GO:0043543 28 25 0,000 0,0380411 0,051608 ! aromatase activity GO:0070330 28 25 0,000 0,0380411 0,05158882 ! cholesterol homeostasis GO:0042632 27 25 0,000 0,0380411 0,05156965 GO:0055092|sterol homeostasis, ! positive regulation of epithelial cell proliferation GO:0050679 29 25 0,000 0,0380411 0,05155049 ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 29 25 0,000 0,0380411 0,05153135 ! response to starvation GO:0042594 26 25 0,000 0,0380411 0,05151222 ! dynein complex GO:0030286 28 25 0,000 0,0380411 0,0514931 ! ARF GTPase activator activity GO:0008060 29 25 0,000 0,0380411 0,051474 ! regulation of behavior GO:0050795 27 25 0,000 0,0380411 0,05145492 ! regulation of biomineral formation GO:0070167 25 25 0,000 0,0380411 0,05143585 ! hexose biosynthetic process GO:0019319 31 25 0,000 0,0380411 0,05141679 ! group transfer coenzyme metabolic process GO:0006752 25 25 0,000 0,0380411 0,05139775 ! hormone transport GO:0009914 31 25 0,000 0,0380411 0,05137872 ! response to molecule of bacterial origin GO:0002237 35 25 0,000 0,0380411 0,0513597 ! cell adhesion molecule binding GO:0050839 29 25 0,000 0,0380411 0,0513407 ! regulation of coagulation GO:0050818 28 25 0,000 0,0380411 0,05132171 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,0380411 0,05130274 ! myeloid leukocyte differentiation GO:0002573 28 25 0,000 0,0380411 0,05128378 ! acetyl-CoA metabolic process GO:0006084 27 25 0,000 0,0380411 0,05126484 ! chromosome, telomeric region GO:0000781 38 25 0,000 0,0380411 0,05124591 ! molting cycle process GO:0022404 28 25 0,000 0,0380411 0,05122699 GO:0022405|hair cycle process, GO:0001942|hair follicle development, ! collagen metabolic process GO:0032963 26 25 0,000 0,0380411 0,05120809 ! xenobiotic metabolic process GO:0006805 27 25 0,000 0,0380411 0,0511892 ! phototransduction GO:0007602 27 25 0,000 0,0380411 0,05117032 ! negative regulation of response to external stimulus GO:0032102 30 25 0,000 0,0380411 0,05115146 ! regulation of endothelial cell proliferation GO:0001936 29 25 0,000 0,0380411 0,05113261 ! protein phosphatase binding GO:0019903 27 25 0,000 0,0380411 0,05111378 ! negative regulation of DNA replication GO:0008156 31 25 0,000 0,0380411 0,05109496 ! multicellular organismal catabolic process GO:0044243 27 25 0,000 0,0380411 0,05107616 ! autophagy GO:0006914 28 25 0,000 0,0380411 0,05105736 ! steroid dehydrogenase activity GO:0016229 27 25 0,000 0,0380411 0,05103859 ! response to ionizing radiation GO:0010212 37 25 0,000 0,0380411 0,05101982 ! DNA-directed DNA polymerase activity GO:0003887 30 25 0,000 0,0380411 0,05100107 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 31 26 0,000 0,0395333 0,05298218 ! positive regulation of cell adhesion GO:0045785 34 26 0,000 0,0395333 0,05296272 ! epidermal growth factor receptor signaling pathway GO:0007173 32 26 0,000 0,0395333 0,05294328 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 29 26 0,000 0,0395333 0,05292385 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 26 0,000 0,0395333 0,05290443 ! positive regulation of lipid metabolic process GO:0045834 27 26 0,000 0,0395333 0,05288503 ! hair cycle GO:0042633 29 26 0,000 0,0395333 0,05286565 GO:0042303|molting cycle, ! thyroid hormone receptor binding GO:0046966 30 26 0,000 0,0395333 0,05284628 ! polysaccharide catabolic process GO:0000272 39 26 0,000 0,0395333 0,05282692 ! peptidyl-tyrosine phosphorylation GO:0018108 30 26 0,000 0,0395333 0,05280757 ! early endosome membrane GO:0031901 31 26 0,000 0,0395333 0,05278825 ! negative regulation of protein kinase cascade GO:0010741 40 26 0,000 0,0395333 0,05276893 ! iron ion homeostasis GO:0055072 29 26 0,000 0,0395333 0,05274963 ! glycolipid metabolic process GO:0006664 36 26 0,000 0,0395333 0,05273034 ! PDZ domain binding GO:0030165 28 26 0,000 0,0395333 0,05271107 ! positive regulation of protein secretion GO:0050714 29 26 0,000 0,0395333 0,05269181 ! regulation of cellular carbohydrate metabolic process GO:0010675 29 26 0,000 0,0395333 0,05267257 ! AP-type membrane coat adaptor complex GO:0030119 30 26 0,000 0,0395333 0,05265334 GO:0030131|clathrin adaptor complex, ! neuromuscular process controlling balance GO:0050885 32 26 0,000 0,0395333 0,05263412 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 45 26 0,000 0,0395333 0,05261492 ! fatty acid binding GO:0005504 28 26 0,000 0,0395333 0,05259573 ! blastocyst development GO:0001824 27 26 0,000 0,0395333 0,05257655 ! regulation of JUN kinase activity GO:0043506 28 26 0,000 0,0395333 0,05255739 ! lysine N-acetyltransferase activity GO:0004468 29 26 0,000 0,0395333 0,05253825 GO:0004402|histone acetyltransferase activity, ! negative regulation of protein polymerization GO:0032272 37 26 0,000 0,0395333 0,05251911 ! regulation of smooth muscle cell proliferation GO:0048660 30 26 0,000 0,0395333 0,0525 ! regulation of actin filament depolymerization GO:0030834 28 26 0,000 0,0395333 0,05248089 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,0395333 0,0524618 ! iron ion transport GO:0006826 33 26 0,000 0,0395333 0,05244272 ! regulation of synaptic plasticity GO:0048167 36 26 0,000 0,0395333 0,05242366 ! glucose transport GO:0015758 27 26 0,000 0,0395333 0,05240461 ! insulin receptor signaling pathway GO:0008286 34 26 0,000 0,0395333 0,05238557 ! spinal cord development GO:0021510 30 26 0,000 0,0395333 0,05236655 ! histone deacetylase complex GO:0000118 29 26 0,000 0,0395333 0,05234755 ! regulation of peptide secretion GO:0002791 30 26 0,000 0,0395333 0,05232855 ! regulation of production of molecular mediator of immune response GO:0002700 27 26 0,000 0,0395333 0,05230957 ! RNA helicase activity GO:0003724 46 26 0,000 0,0395333 0,0522906 ! brush border GO:0005903 30 26 0,000 0,0395333 0,05227165 ! gap junction GO:0005921 29 26 0,000 0,0395333 0,05225271 ! anion:cation symporter activity GO:0015296 29 26 0,000 0,0395333 0,05223379 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 39 27 0,000 0,04102327 0,0541828 ! RNA export from nucleus GO:0006405 31 27 0,000 0,04102327 0,05416319 ! mRNA catabolic process GO:0006402 31 27 0,000 0,04102327 0,0541436 ! myelination GO:0042552 31 27 0,000 0,04102327 0,05412402 ! trans-Golgi network GO:0005802 31 27 0,000 0,04102327 0,05410445 ! transferase activity, transferring nitrogenous groups GO:0016769 29 27 0,000 0,04102327 0,05408489 ! spliceosomal snRNP biogenesis GO:0000387 29 27 0,000 0,04102327 0,05406536 ! solute:solute antiporter activity GO:0015300 28 27 0,000 0,04102327 0,05404583 ! vasculogenesis GO:0001570 32 27 0,000 0,04102327 0,05402632 ! hexose transport GO:0008645 28 27 0,000 0,04102327 0,05400682 GO:0015749|monosaccharide transport, ! regulation of innate immune response GO:0045088 28 27 0,000 0,04102327 0,05398734 ! spindle organization GO:0007051 38 27 0,000 0,04102327 0,05396787 ! cellular response to oxidative stress GO:0034599 32 27 0,000 0,04102327 0,05394842 ! response to organic cyclic substance GO:0014070 34 27 0,000 0,04102327 0,05392897 ! cell fate determination GO:0001709 29 27 0,000 0,04102327 0,05390955 ! lipid oxidation GO:0034440 29 27 0,000 0,04102327 0,05389013 GO:0019395|fatty acid oxidation, ! fatty acid catabolic process GO:0009062 31 27 0,000 0,04102327 0,05387074 ! collagen binding GO:0005518 29 27 0,000 0,04102327 0,05385135 ! carboxy-lyase activity GO:0016831 27 27 0,000 0,04102327 0,05383198 ! phospholipid transporter activity GO:0005548 30 27 0,000 0,04102327 0,05381262 ! liver development GO:0001889 33 27 0,000 0,04102327 0,05379328 ! mitotic sister chromatid segregation GO:0000070 46 27 0,000 0,04102327 0,05377395 ! determination of bilateral symmetry GO:0009855 32 27 0,000 0,04102327 0,05375464 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! integrin complex GO:0008305 30 27 0,000 0,04102327 0,05373533 ! membrane docking GO:0022406 29 27 0,000 0,04102327 0,05371605 ! detection of light stimulus involved in sensory perception GO:0050962 29 27 0,000 0,04102327 0,05369677 GO:0050908|detection of light stimulus involved in visual perception, ! multicellular organismal macromolecule metabolic process GO:0044259 28 27 0,000 0,04102327 0,05367751 ! respiratory gaseous exchange GO:0007585 30 27 0,000 0,04102327 0,05365827 ! phospholipid transport GO:0015914 29 27 0,000 0,04102327 0,05363903 ! sarcoplasmic reticulum GO:0016529 29 27 0,000 0,04102327 0,05361982 ! aminopeptidase activity GO:0004177 33 27 0,000 0,04102327 0,05360061 ! cellular response to nutrient levels GO:0031669 28 27 0,000 0,04102327 0,05358142 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 33 27 0,000 0,04102327 0,05356224 ! biogenic amine biosynthetic process GO:0042401 29 27 0,000 0,04102327 0,05354308 ! negative regulation of transcription regulator activity GO:0090048 32 27 0,000 0,04102327 0,05352393 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 29 27 0,000 0,04102327 0,05350479 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 31 28 0,000 0,04251101 0,05542537 ! Golgi stack GO:0005795 30 28 0,000 0,04251101 0,05540557 ! male gonad development GO:0008584 32 28 0,000 0,04251101 0,05538578 ! regulation of fatty acid metabolic process GO:0019217 41 28 0,000 0,04251101 0,055366 ! lipoprotein binding GO:0008034 31 28 0,000 0,04251101 0,05534625 ! mesoderm formation GO:0001707 34 28 0,000 0,04251101 0,0553265 ! negative regulation of MAP kinase activity GO:0043407 30 28 0,000 0,04251101 0,05530677 ! peptidyl-tyrosine modification GO:0018212 32 28 0,000 0,04251101 0,05528705 ! deoxyribonuclease activity GO:0004536 56 28 0,000 0,04251101 0,05526735 ! nicotinamide metabolic process GO:0006769 32 28 0,000 0,04251101 0,05524766 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 31 28 0,000 0,04251101 0,05522798 ! regulation of osteoblast differentiation GO:0045667 33 28 0,000 0,04251101 0,05520832 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 30 28 0,000 0,04251101 0,05518868 ! negative regulation of neuron apoptosis GO:0043524 39 28 0,000 0,04251101 0,05516904 ! tissue homeostasis GO:0001894 31 28 0,000 0,04251101 0,05514942 GO:0048871|multicellular organismal homeostasis, ! DNA damage checkpoint GO:0000077 48 28 0,000 0,04251101 0,05512982 ! negative regulation of protein complex assembly GO:0031333 39 28 0,000 0,04251101 0,05511023 ! regulation of carbohydrate metabolic process GO:0006109 31 28 0,000 0,04251101 0,05509065 ! sister chromatid segregation GO:0000819 49 28 0,000 0,04251101 0,05507109 ! post-embryonic development GO:0009791 32 28 0,000 0,04251101 0,05505154 ! complement activation, classical pathway GO:0006958 33 28 0,000 0,04251101 0,055032 ! detection of visible light GO:0009584 30 28 0,000 0,04251101 0,05501248 ! calcium-mediated signaling GO:0019722 30 28 0,000 0,04251101 0,05499297 ! receptor regulator activity GO:0030545 31 28 0,000 0,04251101 0,05497348 ! acetylgalactosaminyltransferase activity GO:0008376 33 28 0,000 0,04251101 0,054954 ! symbiosis, encompassing mutualism through parasitism GO:0044403 33 28 0,000 0,04251101 0,05493453 ! response to xenobiotic stimulus GO:0009410 31 28 0,000 0,04251101 0,05491508 ! response to hydrogen peroxide GO:0042542 32 29 0,000 0,04399653 0,05681392 ! hormone binding GO:0042562 31 29 0,000 0,04399653 0,05679382 ! striated muscle cell differentiation GO:0051146 42 29 0,000 0,04399653 0,05677373 ! NADP or NADPH binding GO:0050661 33 29 0,000 0,04399653 0,05675365 ! nucleotide receptor activity, G-protein coupled GO:0001608 31 29 0,000 0,04399653 0,05673359 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 41 29 0,000 0,04399653 0,05671354 ! erythrocyte differentiation GO:0030218 35 29 0,000 0,04399653 0,05669351 ! ceramide metabolic process GO:0006672 29 29 0,000 0,04399653 0,05667349 ! replication fork GO:0005657 42 29 0,000 0,04399653 0,05665349 ! camera-type eye morphogenesis GO:0048593 36 29 0,000 0,04399653 0,0566335 ! monosaccharide biosynthetic process GO:0046364 35 29 0,000 0,04399653 0,05661352 ! negative regulation of lymphocyte activation GO:0051250 32 29 0,000 0,04399653 0,05659356 ! alkaloid metabolic process GO:0009820 33 29 0,000 0,04399653 0,05657361 ! icosanoid biosynthetic process GO:0046456 30 29 0,000 0,04399653 0,05655367 ! regulation of pH GO:0006885 30 29 0,000 0,04399653 0,05653375 ! amino sugar metabolic process GO:0006040 41 29 0,000 0,04399653 0,05651385 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 34 29 0,000 0,04399653 0,05649395 ! phospholipase C activity GO:0004629 43 29 0,000 0,04399653 0,05647408 ! response to mechanical stimulus GO:0009612 33 29 0,000 0,04399653 0,05645421 ! clathrin coated vesicle membrane GO:0030665 33 29 0,000 0,04399653 0,05643436 ! sodium channel activity GO:0005272 33 29 0,000 0,04399653 0,05641453 ! sarcoplasm GO:0016528 31 29 0,000 0,04399653 0,0563947 ! detection of light stimulus GO:0009583 31 29 0,000 0,04399653 0,05637489 ! spermatid development GO:0007286 30 29 0,000 0,04399653 0,0563551 ! DNA polymerase activity GO:0034061 34 29 0,000 0,04399653 0,05633532 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 31 29 0,000 0,04399653 0,05631555 ! sarcolemma GO:0042383 30 29 0,000 0,04399653 0,0562958 ! tumor necrosis factor receptor superfamily binding GO:0032813 31 29 0,000 0,04399653 0,05627606 ! galactosyltransferase activity GO:0008378 33 29 0,000 0,04399653 0,05625634 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,04399653 0,05623662 ! transforming growth factor beta receptor signaling pathway GO:0007179 34 30 0,000 0,04547981 0,05811221 ! mitochondrial nucleoid GO:0042645 44 30 0,000 0,04547981 0,05809186 GO:0009295|nucleoid, ! cholesterol transport GO:0030301 33 30 0,000 0,04547981 0,05807153 GO:0015918|sterol transport, ! histone-lysine N-methyltransferase activity GO:0018024 34 30 0,000 0,04547981 0,05805121 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! cellular carbohydrate biosynthetic process GO:0034637 30 30 0,000 0,04547981 0,0580309 ! scavenger receptor activity GO:0005044 39 30 0,000 0,04547981 0,05801061 ! spliceosome assembly GO:0000245 34 30 0,000 0,04547981 0,05799034 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 39 30 0,000 0,04547981 0,05797007 GO:0004601|peroxidase activity, ! mesoderm morphogenesis GO:0048332 37 30 0,000 0,04547981 0,05794983 ! metanephros development GO:0001656 31 30 0,000 0,04547981 0,05792959 ! cyclic nucleotide metabolic process GO:0009187 31 30 0,000 0,04547981 0,05790937 ! positive regulation of MAPKKK cascade GO:0043410 36 30 0,000 0,04547981 0,05788917 ! regulation of macrophage differentiation GO:0045649 37 30 0,000 0,04547981 0,05786898 ! positive regulation of myeloid cell differentiation GO:0045639 37 30 0,000 0,04547981 0,0578488 ! negative regulation of myeloid cell differentiation GO:0045638 35 30 0,000 0,04547981 0,05782863 ! cis-trans isomerase activity GO:0016859 32 30 0,000 0,04547981 0,05780849 ! myeloid leukocyte activation GO:0002274 36 30 0,000 0,04547981 0,05778835 ! negative regulation of protein transport GO:0051224 34 30 0,000 0,04547981 0,05776823 ! condensed nuclear chromosome GO:0000794 31 30 0,000 0,04547981 0,05774812 ! cortical cytoskeleton GO:0030863 33 30 0,000 0,04547981 0,05772803 ! protein-lipid complex GO:0032994 41 30 0,000 0,04547981 0,05770795 GO:0034358|plasma lipoprotein particle, ! circadian rhythm GO:0007623 37 30 0,000 0,04547981 0,05768788 ! negative regulation of protein modification process GO:0031400 34 30 0,000 0,04547981 0,05766783 ! phosphatase binding GO:0019902 34 30 0,000 0,04547981 0,05764779 ! acute-phase response GO:0006953 44 30 0,000 0,04547981 0,05762777 ! segmentation GO:0035282 37 30 0,000 0,04547981 0,05760776 ! response to toxin GO:0009636 33 30 0,000 0,04547981 0,05758777 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,04547981 0,05756778 ! antigen binding GO:0003823 33 30 0,000 0,04547981 0,05754782 ! regulation of systemic arterial blood pressure GO:0003073 33 30 0,000 0,04547981 0,05752786 ! Golgi-associated vesicle membrane GO:0030660 37 30 0,000 0,04547981 0,05750792 ! ensheathment of neurons GO:0007272 35 30 0,000 0,04547981 0,057488 GO:0008366|axon ensheathment, ! JAK-STAT cascade GO:0007259 43 30 0,000 0,04547981 0,05746808 ! regulation of microtubule-based process GO:0032886 41 30 0,000 0,04547981 0,05744818 ! vesicle localization GO:0051648 31 30 0,000 0,04547981 0,0574283 ! negative regulation of cell adhesion GO:0007162 34 31 0,000 0,04696088 0,05927795 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,04696088 0,05925745 ! acrosomal vesicle GO:0001669 34 31 0,000 0,04696088 0,05923696 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,04696088 0,05921648 ! regulation of axonogenesis GO:0050770 37 31 0,000 0,04696088 0,05919602 ! regulation of T cell differentiation GO:0045580 43 31 0,000 0,04696088 0,05917557 ! formation of primary germ layer GO:0001704 37 31 0,000 0,04696088 0,05915514 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 33 31 0,000 0,04696088 0,05913472 ! endocytic vesicle GO:0030139 33 31 0,000 0,04696088 0,05911431 ! pyridine nucleotide metabolic process GO:0019362 35 31 0,000 0,04696088 0,05909392 ! spermatid differentiation GO:0048515 32 31 0,000 0,04696088 0,05907354 ! negative regulation of catabolic process GO:0009895 34 31 0,000 0,04696088 0,05905318 ! neuron fate commitment GO:0048663 44 31 0,000 0,04696088 0,05903283 ! regulation of cellular catabolic process GO:0031329 35 31 0,000 0,04696088 0,0590125 ! regulation of JAK-STAT cascade GO:0046425 37 31 0,000 0,04696088 0,05899217 ! morphogenesis of embryonic epithelium GO:0016331 36 31 0,000 0,04696088 0,05897187 ! macromolecular complex disassembly GO:0032984 37 31 0,000 0,04696088 0,05895157 ! cell junction assembly GO:0034329 36 31 0,000 0,04696088 0,0589313 ! drug binding GO:0008144 34 31 0,000 0,04696088 0,05891103 ! positive regulation of T cell proliferation GO:0042102 38 31 0,000 0,04696088 0,05889078 ! peptide transport GO:0015833 36 31 0,000 0,04696088 0,05887054 ! DNA integrity checkpoint GO:0031570 51 31 0,000 0,04696088 0,05885032 ! peripheral nervous system development GO:0007422 35 31 0,000 0,04696088 0,05883011 ! I band GO:0031674 34 31 0,000 0,04696088 0,05880991 ! BMP signaling pathway GO:0030509 33 31 0,000 0,04696088 0,05878973 ! adult locomotory behavior GO:0008344 37 31 0,000 0,04696088 0,05876956 ! gene silencing GO:0016458 33 31 0,000 0,04696088 0,05874941 ! negative regulation of secretion GO:0051048 37 32 0,000 0,04843972 0,06057871 ! negative regulation of DNA metabolic process GO:0051053 38 32 0,000 0,04843972 0,06055795 ! phosphotransferase activity, phosphate group as acceptor GO:0016776 49 32 0,000 0,04843972 0,06053721 ! meiosis I GO:0007127 53 32 0,000 0,04843972 0,06051647 ! GPI anchor biosynthetic process GO:0006506 35 32 0,000 0,04843972 0,06049576 GO:0006505|GPI anchor metabolic process, ! unsaturated fatty acid biosynthetic process GO:0006636 33 32 0,000 0,04843972 0,06047505 ! sterol biosynthetic process GO:0016126 40 32 0,000 0,04843972 0,06045436 ! vesicle coat GO:0030120 39 32 0,000 0,04843972 0,06043369 ! cytokine production GO:0001816 32 32 0,000 0,04843972 0,06041303 ! regulation of calcium ion transport GO:0051924 37 32 0,000 0,04843972 0,06039238 ! proteoglycan metabolic process GO:0006029 34 32 0,000 0,04843972 0,06037175 ! sphingoid metabolic process GO:0046519 33 32 0,000 0,04843972 0,06035113 ! multicellular organismal metabolic process GO:0044236 35 32 0,000 0,04843972 0,06033052 ! oxygen binding GO:0019825 33 32 0,000 0,04843972 0,06030993 ! leukocyte chemotaxis GO:0030595 32 32 0,000 0,04843972 0,06028936 GO:0060326|cell chemotaxis, ! negative regulation of leukocyte activation GO:0002695 35 32 0,000 0,04843972 0,06026879 ! hormone biosynthetic process GO:0042446 32 32 0,000 0,04843972 0,06024824 ! double-stranded RNA binding GO:0003725 35 32 0,000 0,04843972 0,06022771 ! microtubule organizing center part GO:0044450 46 32 0,000 0,04843972 0,06020719 ! platelet alpha granule lumen GO:0031093 35 33 0,000 0,04991635 0,06202141 ! DNA helicase activity GO:0003678 55 33 0,000 0,04991635 0,06200029 ! neural tube development GO:0021915 37 33 0,000 0,04991635 0,06197918 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 33 0,000 0,04991635 0,0619581 ! pigment biosynthetic process GO:0046148 35 33 0,000 0,04991635 0,06193702 ! organelle envelope lumen GO:0031970 46 33 0,000 0,04991635 0,06191596 ! regulation of cellular ketone metabolic process GO:0010565 46 33 0,000 0,04991635 0,06189492 ! negative regulation of DNA binding GO:0043392 39 33 0,000 0,04991635 0,06187389 ! NAD or NADH binding GO:0051287 36 33 0,000 0,04991635 0,06185287 ! nucleotide catabolic process GO:0009166 35 33 0,000 0,04991635 0,06183187 ! B cell differentiation GO:0030183 37 33 0,000 0,04991635 0,06181088 ! aerobic respiration GO:0009060 35 33 0,000 0,04991635 0,0617899 ! embryonic organ development GO:0048568 41 33 0,000 0,04991635 0,06176894 ! placenta development GO:0001890 39 33 0,000 0,04991635 0,061748 ! protein serine/threonine phosphatase complex GO:0008287 37 33 0,000 0,04991635 0,06172707 ! tissue remodeling GO:0048771 37 33 0,000 0,04991635 0,06170615 ! flagellum GO:0019861 34 33 0,000 0,04991635 0,06168525 ! L-amino acid transmembrane transporter activity GO:0015179 37 33 0,000 0,04991635 0,06166436 ! Rho protein signal transduction GO:0007266 35 33 0,000 0,04991635 0,06164348 ! cysteine-type endopeptidase inhibitor activity GO:0004869 35 33 0,000 0,04991635 0,06162262 ! odontogenesis GO:0042476 39 34 0,000 0,05139077 0,06342135 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,05139077 0,0633999 ! lipid homeostasis GO:0055088 37 34 0,000 0,05139077 0,06337847 ! telencephalon development GO:0021537 36 34 0,000 0,05139077 0,06335705 ! negative regulation of hydrolase activity GO:0051346 36 34 0,000 0,05139077 0,06333565 ! clathrin coat GO:0030118 41 34 0,000 0,05139077 0,06331426 ! cell growth GO:0016049 36 34 0,000 0,05139077 0,06329288 ! protein polymerization GO:0051258 38 34 0,000 0,05139077 0,06327152 ! learning GO:0007612 51 34 0,000 0,05139077 0,06325017 ! keratinization GO:0031424 40 34 0,000 0,05139077 0,06322884 ! ovulation cycle process GO:0022602 35 34 0,000 0,05139077 0,06320752 ! regulation of striated muscle tissue development GO:0016202 40 34 0,000 0,05139077 0,06318622 ! steroid hormone receptor binding GO:0035258 44 34 0,000 0,05139077 0,06316493 ! regulation of protein import into nucleus GO:0042306 36 34 0,000 0,05139077 0,06314366 ! erythrocyte homeostasis GO:0034101 40 34 0,000 0,05139077 0,0631224 ! amino acid binding GO:0016597 40 34 0,000 0,05139077 0,06310115 ! regulation of protein stability GO:0031647 35 34 0,000 0,05139077 0,06307992 ! specific RNA polymerase II transcription factor activity GO:0003704 41 34 0,000 0,05139077 0,0630587 ! glycogen metabolic process GO:0005977 48 34 0,000 0,05139077 0,0630375 ! pyrimidine nucleotide metabolic process GO:0006220 41 34 0,000 0,05139077 0,06301631 ! acetylglucosaminyltransferase activity GO:0008375 40 34 0,000 0,05139077 0,06299513 ! epithelial tube morphogenesis GO:0060562 38 34 0,000 0,05139077 0,06297397 ! positive regulation of transcription factor activity GO:0051091 49 35 0,000 0,05286297 0,06475626 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 53 35 0,000 0,05286297 0,06473452 ! response to estrogen stimulus GO:0043627 48 35 0,000 0,05286297 0,0647128 ! inner ear morphogenesis GO:0042472 46 35 0,000 0,05286297 0,06469109 ! MHC protein complex GO:0042611 50 35 0,000 0,05286297 0,06466939 ! alcohol biosynthetic process GO:0046165 41 35 0,000 0,05286297 0,06464771 ! vesicle lumen GO:0031983 38 35 0,000 0,05286297 0,06462605 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! female gonad development GO:0008585 37 35 0,000 0,05286297 0,0646044 ! mesenchymal cell development GO:0014031 40 35 0,000 0,05286297 0,06458276 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! neutral lipid metabolic process GO:0006638 47 35 0,000 0,05286297 0,06456114 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 37 35 0,000 0,05286297 0,06453953 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 41 35 0,000 0,05286297 0,06451794 ! regulation of proteolysis GO:0030162 37 35 0,000 0,05286297 0,06449636 ! ovulation cycle GO:0042698 37 35 0,000 0,05286297 0,0644748 ! intramolecular oxidoreductase activity GO:0016860 35 35 0,000 0,05286297 0,06445325 ! positive regulation of catabolic process GO:0009896 38 35 0,000 0,05286297 0,06443172 ! collagen GO:0005581 54 35 0,000 0,05286297 0,0644102 ! glucan metabolic process GO:0044042 49 35 0,000 0,05286297 0,06438869 GO:0006073|cellular glucan metabolic process, ! regulation of muscle development GO:0048634 42 35 0,000 0,05286297 0,0643672 ! ER to Golgi vesicle-mediated transport GO:0006888 43 35 0,000 0,05286297 0,06434572 ! histone methyltransferase activity GO:0042054 40 35 0,000 0,05286297 0,06432426 ! cation:sugar symporter activity GO:0005402 37 35 0,000 0,05286297 0,06430281 GO:0005351|sugar:hydrogen symporter activity, ! carbohydrate homeostasis GO:0033500 49 35 0,000 0,05286297 0,06428138 GO:0042593|glucose homeostasis, ! cytosolic small ribosomal subunit GO:0022627 36 35 0,000 0,05286297 0,06425996 ! maintenance of protein location GO:0045185 45 35 0,000 0,05286297 0,06423855 ! polyol metabolic process GO:0019751 46 35 0,000 0,05286297 0,06421716 ! androgen receptor signaling pathway GO:0030521 47 35 0,000 0,05286297 0,06419578 ! cytokinesis GO:0000910 38 35 0,000 0,05286297 0,06417442 ! O-acyltransferase activity GO:0008374 36 35 0,000 0,05286297 0,06415307 ! purinergic nucleotide receptor activity GO:0001614 40 36 0,000 0,05433298 0,0659151 GO:0016502|nucleotide receptor activity, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 42 36 0,000 0,05433298 0,06589318 ! positive regulation of neurogenesis GO:0050769 38 36 0,000 0,05433298 0,06587128 ! SMAD binding GO:0046332 39 36 0,000 0,05433298 0,0658494 ! negative regulation of cell activation GO:0050866 40 36 0,000 0,05433298 0,06582753 ! inositol or phosphatidylinositol kinase activity GO:0004428 51 36 0,000 0,05433298 0,06580568 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 36 0,000 0,05433298 0,06578383 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 38 36 0,000 0,05433298 0,06576201 ! hormone-mediated signaling GO:0009755 41 36 0,000 0,05433298 0,0657402 ! nucleus organization GO:0006997 42 36 0,000 0,05433298 0,0657184 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 44 36 0,000 0,05433298 0,06569662 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 42 36 0,000 0,05433298 0,06567485 ! carboxypeptidase activity GO:0004180 37 36 0,000 0,05433298 0,0656531 ! energy coupled proton transport, down electrochemical gradient GO:0015985 37 36 0,000 0,05433298 0,06563136 GO:0015986|ATP synthesis coupled proton transport, ! female gamete generation GO:0007292 39 36 0,000 0,05433298 0,06560963 ! maintenance of location in cell GO:0051651 38 36 0,000 0,05433298 0,06558792 ! activation of adenylate cyclase activity GO:0007190 44 37 0,000 0,05580077 0,06733749 ! regulation of hormone secretion GO:0046883 43 37 0,000 0,05580077 0,06731522 ! sugar transmembrane transporter activity GO:0051119 39 37 0,000 0,05580077 0,06729297 GO:0015144|carbohydrate transmembrane transporter activity, ! regulation of Rab protein signal transduction GO:0032483 40 37 0,000 0,05580077 0,06727073 GO:0032313|regulation of Rab GTPase activity, ! regulation of action potential in neuron GO:0019228 44 37 0,000 0,05580077 0,0672485 ! glycerol ether metabolic process GO:0006662 49 37 0,000 0,05580077 0,0672263 ! endoribonuclease activity GO:0004521 48 37 0,000 0,05580077 0,0672041 ! hindbrain development GO:0030902 43 37 0,000 0,05580077 0,06718192 ! isoprenoid metabolic process GO:0006720 41 37 0,000 0,05580077 0,06715976 ! pigmentation GO:0043473 51 37 0,000 0,05580077 0,06713761 ! regulation of neuron projection development GO:0010975 43 37 0,000 0,05580077 0,06711547 ! metalloexopeptidase activity GO:0008235 39 37 0,000 0,05580077 0,06709335 ! monocarboxylic acid transport GO:0015718 43 37 0,000 0,05580077 0,06707124 ! sensory perception of taste GO:0050909 37 37 0,000 0,05580077 0,06704915 ! skeletal muscle fiber development GO:0048741 41 37 0,000 0,05580077 0,06702707 ! development of primary female sexual characteristics GO:0046545 40 37 0,000 0,05580077 0,06700501 GO:0046660|female sex differentiation, ! ion transmembrane transport GO:0034220 38 37 0,000 0,05580077 0,06698296 ! regulation of lymphocyte mediated immunity GO:0002706 43 37 0,000 0,05580077 0,06696093 ! coated pit GO:0005905 44 37 0,000 0,05580077 0,06693891 ! positive regulation of adenylate cyclase activity GO:0045762 45 38 0,000 0,05726637 0,06867447 ! negative regulation of binding GO:0051100 44 38 0,000 0,05726637 0,0686519 ! organic ether metabolic process GO:0018904 50 38 0,000 0,05726637 0,06862935 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 43 38 0,000 0,05726637 0,06860681 ! regulation of lymphocyte differentiation GO:0045619 51 38 0,000 0,05726637 0,06858428 ! carbon-carbon lyase activity GO:0016830 41 38 0,000 0,05726637 0,06856177 ! synapse organization GO:0050808 43 38 0,000 0,05726637 0,06853928 ! viral infectious cycle GO:0019058 40 38 0,000 0,05726637 0,0685168 ! phosphoinositide biosynthetic process GO:0046489 41 38 0,000 0,05726637 0,06849434 ! negative regulation of protein complex disassembly GO:0043242 42 38 0,000 0,05726637 0,06847189 ! organic anion transport GO:0015711 42 38 0,000 0,05726637 0,06844945 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 52 38 0,000 0,05726637 0,06842703 ! monosaccharide binding GO:0048029 41 38 0,000 0,05726637 0,06840463 ! muscle fiber development GO:0048747 42 38 0,000 0,05726637 0,06838223 ! development of primary male sexual characteristics GO:0046546 46 38 0,000 0,05726637 0,06835986 ! phagocytosis GO:0006909 44 38 0,000 0,05726637 0,0683375 ! regulation of ARF protein signal transduction GO:0032012 44 38 0,000 0,05726637 0,06831515 ! general RNA polymerase II transcription factor activity GO:0016251 43 38 0,000 0,05726637 0,06829282 ! DNA-directed RNA polymerase activity GO:0003899 49 38 0,000 0,05726637 0,0682705 GO:0034062|RNA polymerase activity, ! extrinsic to plasma membrane GO:0019897 43 38 0,000 0,05726637 0,0682482 ! cytosolic large ribosomal subunit GO:0022625 43 38 0,000 0,05726637 0,06822591 ! Rab GTPase activator activity GO:0005097 41 38 0,000 0,05726637 0,06820363 ! cellular response to insulin stimulus GO:0032869 47 38 0,000 0,05726637 0,06818137 ! monocarboxylic acid binding GO:0033293 44 39 0,000 0,05872977 0,06990089 ! induction of apoptosis by extracellular signals GO:0008624 44 39 0,000 0,05872977 0,06987809 ! heterocycle biosynthetic process GO:0018130 51 39 0,000 0,05872977 0,0698553 ! positive regulation of DNA binding GO:0043388 53 39 0,000 0,05872977 0,06983253 ! T cell differentiation GO:0030217 64 39 0,000 0,05872977 0,06980978 ! DNA-dependent ATPase activity GO:0008094 63 39 0,000 0,05872977 0,06978704 ! cell fate specification GO:0001708 55 39 0,000 0,05872977 0,06976432 ! positive regulation of cyclase activity GO:0031281 46 39 0,000 0,05872977 0,06974161 ! regulation of adaptive immune response GO:0002819 44 39 0,000 0,05872977 0,06971891 ! regulation of cell morphogenesis involved in differentiation GO:0010769 45 39 0,000 0,05872977 0,06969623 ! receptor-mediated endocytosis GO:0006898 44 39 0,000 0,05872977 0,06967357 ! regulation of metal ion transport GO:0010959 45 39 0,000 0,05872977 0,06965092 ! energy reserve metabolic process GO:0006112 53 39 0,000 0,05872977 0,06962828 ! amine receptor activity GO:0008227 48 39 0,000 0,05872977 0,06960566 ! cytoskeleton-dependent intracellular transport GO:0030705 42 39 0,000 0,05872977 0,06958305 ! embryonic skeletal system morphogenesis GO:0048704 46 39 0,000 0,05872977 0,06956046 ! neuropeptide receptor activity GO:0008188 41 39 0,000 0,05872977 0,06953788 ! double-strand break repair GO:0006302 70 39 0,000 0,05872977 0,06951532 ! pigment metabolic process GO:0042440 43 39 0,000 0,05872977 0,06949277 ! RNA modification GO:0009451 39 39 0,000 0,05872977 0,06947024 ! damaged DNA binding GO:0003684 51 40 0,000 0,06019098 0,07117559 ! regulation of intracellular protein transport GO:0033157 43 40 0,000 0,06019098 0,07115253 ! peroxisomal membrane GO:0005778 44 40 0,000 0,06019098 0,07112948 GO:0031903|microbody membrane, ! actin filament binding GO:0051015 41 40 0,000 0,06019098 0,07110645 ! positive regulation of cell development GO:0010720 43 40 0,000 0,06019098 0,07108343 ! ribonucleoside metabolic process GO:0009119 47 40 0,000 0,06019098 0,07106042 ! biopolymer methylation GO:0043414 45 40 0,000 0,06019098 0,07103743 ! neuron migration GO:0001764 43 40 0,000 0,06019098 0,07101446 ! regulation of protein secretion GO:0050708 45 40 0,000 0,06019098 0,0709915 ! oxidoreduction coenzyme metabolic process GO:0006733 45 40 0,000 0,06019098 0,07096855 ! dorsal/ventral pattern formation GO:0009953 42 40 0,000 0,06019098 0,07094562 ! regulation of actin filament polymerization GO:0030833 53 40 0,000 0,06019098 0,07092271 ! positive regulation of defense response GO:0031349 41 40 0,000 0,06019098 0,07089981 ! mammary gland development GO:0030879 47 40 0,000 0,06019098 0,07087692 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 50 40 0,000 0,06019098 0,07085405 ! neuropeptide binding GO:0042923 42 40 0,000 0,06019098 0,0708312 ! regulation of tube size GO:0035150 44 40 0,000 0,06019098 0,07080835 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 42 40 0,000 0,06019098 0,07078553 ! positive regulation of gene-specific transcription GO:0043193 46 40 0,000 0,06019098 0,07076272 ! regulation of leukocyte mediated immunity GO:0002703 46 40 0,000 0,06019098 0,07073992 ! inorganic anion transmembrane transporter activity GO:0015103 43 40 0,000 0,06019098 0,07071714 ! chromatin remodeling GO:0006338 44 40 0,000 0,06019098 0,07069437 ! solute:hydrogen symporter activity GO:0015295 44 40 0,000 0,06019098 0,07067161 ! protein amino acid N-linked glycosylation GO:0006487 46 41 0,000 0,06165 0,07236139 ! Notch signaling pathway GO:0007219 46 41 0,000 0,06165 0,07233812 ! keratin filament GO:0045095 44 41 0,000 0,06165 0,07231486 ! peptide metabolic process GO:0006518 42 41 0,000 0,06165 0,07229161 ! polysaccharide biosynthetic process GO:0000271 42 41 0,000 0,06165 0,07226838 ! late endosome membrane GO:0031902 45 41 0,000 0,06165 0,07224517 ! icosanoid metabolic process GO:0006690 51 41 0,000 0,06165 0,07222197 ! positive regulation of lyase activity GO:0051349 48 41 0,000 0,06165 0,07219878 ! integral to endoplasmic reticulum membrane GO:0030176 43 41 0,000 0,06165 0,07217561 ! lamellipodium GO:0030027 56 41 0,000 0,06165 0,07215246 ! branching morphogenesis of a tube GO:0048754 54 41 0,000 0,06165 0,07212932 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 51 41 0,000 0,06165 0,07210619 ! proton-transporting two-sector ATPase complex GO:0016469 42 41 0,000 0,06165 0,07208308 ! response to reactive oxygen species GO:0000302 49 42 0,000 0,06310683 0,07376281 ! cellular amide metabolic process GO:0043603 56 42 0,000 0,06310683 0,07373918 ! ER-Golgi intermediate compartment GO:0005793 52 42 0,000 0,06310683 0,07371557 ! regulation of multicellular organism growth GO:0040014 46 42 0,000 0,06310683 0,07369197 ! integral to Golgi membrane GO:0030173 55 42 0,000 0,06310683 0,07366839 ! nuclear export GO:0051168 46 42 0,000 0,06310683 0,07364483 ! developmental growth GO:0048589 45 42 0,000 0,06310683 0,07362127 ! structural constituent of muscle GO:0008307 46 42 0,000 0,06310683 0,07359774 ! mitochondrial transport GO:0006839 45 42 0,000 0,06310683 0,07357422 ! protein methyltransferase activity GO:0008276 49 42 0,000 0,06310683 0,07355071 ! feeding behavior GO:0007631 48 42 0,000 0,06310683 0,07352722 ! protein serine/threonine phosphatase activity GO:0004722 45 42 0,000 0,06310683 0,07350374 ! ribonucleoprotein complex assembly GO:0022618 47 42 0,000 0,06310683 0,07348028 ! RNA catabolic process GO:0006401 49 43 0,000 0,06456148 0,07515006 ! ear morphogenesis GO:0042471 56 43 0,000 0,06456148 0,07512609 ! cellular amino acid biosynthetic process GO:0008652 49 43 0,000 0,06456148 0,07510213 ! regulation of epithelial cell proliferation GO:0050678 50 43 0,000 0,06456148 0,07507819 ! positive regulation of growth GO:0045927 47 43 0,000 0,06456148 0,07505426 ! cell recognition GO:0008037 51 43 0,000 0,06456148 0,07503035 ! positive regulation of cytokine production GO:0001819 46 43 0,000 0,06456148 0,07500646 ! epithelial cell differentiation GO:0030855 56 43 0,000 0,06456148 0,07498258 ! gliogenesis GO:0042063 46 43 0,000 0,06456148 0,07495871 ! endosome transport GO:0016197 48 43 0,000 0,06456148 0,07493486 ! striated muscle contraction GO:0006941 45 43 0,000 0,06456148 0,07491103 ! positive regulation of cytokine biosynthetic process GO:0042108 48 43 0,000 0,06456148 0,07488721 ! antioxidant activity GO:0016209 53 43 0,000 0,06456148 0,07486341 ! sulfur compound biosynthetic process GO:0044272 47 43 0,000 0,06456148 0,07483962 ! activation of caspase activity GO:0006919 60 43 0,000 0,06456148 0,07481584 ! vascular process in circulatory system GO:0003018 48 43 0,000 0,06456148 0,07479209 ! histone modification GO:0016570 45 43 0,000 0,06456148 0,07476834 ! cellular amino acid derivative biosynthetic process GO:0042398 55 43 0,000 0,06456148 0,07474461 ! regulation of nucleocytoplasmic transport GO:0046822 46 44 0,000 0,06601395 0,07640193 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 50 44 0,000 0,06601395 0,0763777 ! negative regulation of cell migration GO:0030336 53 44 0,000 0,06601395 0,07635348 ! nucleoside monophosphate biosynthetic process GO:0009124 50 44 0,000 0,06601395 0,07632928 ! chemokine activity GO:0008009 48 44 0,000 0,06601395 0,07630509 ! ruffle GO:0001726 50 44 0,000 0,06601395 0,07628092 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 51 44 0,000 0,06601395 0,07625677 ! regulation of neuron apoptosis GO:0043523 58 44 0,000 0,06601395 0,07623263 ! cartilage development GO:0051216 48 44 0,000 0,06601395 0,0762085 ! membrane fusion GO:0006944 52 44 0,000 0,06601395 0,0761844 ! channel regulator activity GO:0016247 54 44 0,000 0,06601395 0,0761603 ! excretion GO:0007588 53 44 0,000 0,06601395 0,07613622 ! male sex differentiation GO:0046661 52 44 0,000 0,06601395 0,07611216 ! protein phosphatase regulator activity GO:0019888 50 44 0,000 0,06601395 0,07608811 ! RNA elongation from RNA polymerase II promoter GO:0006368 49 44 0,000 0,06601395 0,07606408 ! amino acid activation GO:0043038 45 44 0,000 0,06601395 0,07604006 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! microbody part GO:0044438 48 44 0,000 0,06601395 0,07601606 GO:0044439|peroxisomal part, ! positive regulation of binding GO:0051099 59 45 0,000 0,06746424 0,07766157 ! solute:sodium symporter activity GO:0015370 51 45 0,000 0,06746424 0,07763708 ! transferase activity, transferring pentosyl groups GO:0016763 50 45 0,000 0,06746424 0,07761259 ! organellar ribosome GO:0000313 46 45 0,000 0,06746424 0,07758812 GO:0005761|mitochondrial ribosome, ! platelet alpha granule GO:0031091 49 45 0,000 0,06746424 0,07756367 ! single-stranded DNA binding GO:0003697 48 45 0,000 0,06746424 0,07753923 ! intrinsic to Golgi membrane GO:0031228 60 45 0,000 0,06746424 0,07751481 ! transport vesicle GO:0030133 53 45 0,000 0,06746424 0,07749041 ! regulation of endocytosis GO:0030100 52 45 0,000 0,06746424 0,07746601 ! ligase activity, forming carbon-oxygen bonds GO:0016875 47 45 0,000 0,06746424 0,07744164 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! regulation of protein complex disassembly GO:0043244 49 45 0,000 0,06746424 0,07741728 ! nuclear matrix GO:0016363 56 45 0,000 0,06746424 0,07739293 ! unsaturated fatty acid metabolic process GO:0033559 55 45 0,000 0,06746424 0,0773686 ! regulation of T cell proliferation GO:0042129 53 45 0,000 0,06746424 0,07734429 ! regulation of myeloid leukocyte differentiation GO:0002761 54 45 0,000 0,06746424 0,07731999 ! DNA-dependent DNA replication GO:0006261 66 45 0,000 0,06746424 0,07729571 ! coated vesicle membrane GO:0030662 52 45 0,000 0,06746424 0,07727144 ! covalent chromatin modification GO:0016569 47 45 0,000 0,06746424 0,07724718 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 51 45 0,000 0,06746424 0,07722295 ! synaptosome GO:0019717 50 45 0,000 0,06746424 0,07719872 ! chemokine receptor binding GO:0042379 50 45 0,000 0,06746424 0,07717452 ! regulation of action potential GO:0001508 56 46 0,000 0,06891235 0,07880635 ! immunoglobulin mediated immune response GO:0016064 51 46 0,000 0,06891235 0,07878165 ! phosphatase regulator activity GO:0019208 53 46 0,000 0,06891235 0,07875697 ! regulation of inflammatory response GO:0050727 49 46 0,000 0,06891235 0,07873231 ! regulation of JNK cascade GO:0046328 53 46 0,000 0,06891235 0,07870766 ! methylation GO:0032259 51 46 0,000 0,06891235 0,07868302 ! positive regulation of protein transport GO:0051222 50 46 0,000 0,06891235 0,0786584 ! regulation of ion transport GO:0043269 54 46 0,000 0,06891235 0,0786338 ! leukocyte migration GO:0050900 49 46 0,000 0,06891235 0,07860921 ! neuromuscular process GO:0050905 56 46 0,000 0,06891235 0,07858464 ! sulfotransferase activity GO:0008146 54 46 0,000 0,06891235 0,07856008 ! JNK cascade GO:0007254 48 46 0,000 0,06891235 0,07853554 ! SH3/SH2 adaptor activity GO:0005070 52 46 0,000 0,06891235 0,07851101 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 54 47 0,000 0,07035829 0,08013333 ! auxiliary transport protein activity GO:0015457 58 47 0,000 0,07035829 0,08010832 ! regulation of actin polymerization or depolymerization GO:0008064 60 47 0,000 0,07035829 0,08008332 ! microtubule binding GO:0008017 61 47 0,000 0,07035829 0,08005834 ! morphogenesis of a branching structure GO:0001763 70 47 0,000 0,07035829 0,08003338 ! regulation of protein polymerization GO:0032271 60 47 0,000 0,07035829 0,08000843 ! viral reproductive process GO:0022415 53 47 0,000 0,07035829 0,0799835 ! RNA elongation GO:0006354 52 47 0,000 0,07035829 0,07995858 ! negative regulation of immune system process GO:0002683 58 47 0,000 0,07035829 0,07993368 ! mRNA binding GO:0003729 65 47 0,000 0,07035829 0,0799088 ! response to insulin stimulus GO:0032868 57 47 0,000 0,07035829 0,07988393 ! axon GO:0030424 53 48 0,000 0,07180207 0,0814978 ! protein amino acid lipidation GO:0006497 53 48 0,000 0,07180207 0,08147245 ! stress-activated protein kinase signaling pathway GO:0031098 50 48 0,000 0,07180207 0,08144712 ! proteasome complex GO:0000502 50 48 0,000 0,07180207 0,0814218 ! glutamine family amino acid metabolic process GO:0009064 62 48 0,000 0,07180207 0,0813965 ! protein homooligomerization GO:0051260 63 48 0,000 0,07180207 0,08137122 ! regulation of cell projection organization GO:0031344 54 48 0,000 0,07180207 0,08134594 ! positive regulation of caspase activity GO:0043280 65 48 0,000 0,07180207 0,08132069 GO:0010952|positive regulation of peptidase activity, ! detection of stimulus involved in sensory perception GO:0050906 53 48 0,000 0,07180207 0,08129545 ! growth factor receptor binding GO:0070851 58 48 0,000 0,07180207 0,08127023 ! N-methyltransferase activity GO:0008170 53 48 0,000 0,07180207 0,08124502 ! inner ear development GO:0048839 60 48 0,000 0,07180207 0,08121983 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 57 48 0,000 0,07180207 0,08119465 ! amino acid transmembrane transporter activity GO:0015171 53 48 0,000 0,07180207 0,08116949 ! chromatin remodeling complex GO:0016585 54 48 0,000 0,07180207 0,08114434 ! B cell mediated immunity GO:0019724 53 48 0,000 0,07180207 0,08111921 ! steroid hormone receptor activity GO:0003707 61 48 0,000 0,07180207 0,0810941 ! regulation of cell shape GO:0008360 55 48 0,000 0,07180207 0,081069 ! protein N-terminus binding GO:0047485 57 48 0,000 0,07180207 0,08104392 ! establishment of organelle localization GO:0051656 58 48 0,000 0,07180207 0,08101885 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 52 49 0,000 0,07324368 0,08261996 ! regulation of neurotransmitter levels GO:0001505 55 49 0,000 0,07324368 0,08259442 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 54 49 0,000 0,07324368 0,08256889 ! Golgi-associated vesicle GO:0005798 59 49 0,000 0,07324368 0,08254338 ! lipid modification GO:0030258 55 49 0,000 0,07324368 0,08251789 ! synaptic vesicle GO:0008021 56 49 0,000 0,07324368 0,08249242 ! regulation of gene expression, epigenetic GO:0040029 64 49 0,000 0,07324368 0,08246696 ! pyridoxal phosphate binding GO:0030170 63 49 0,000 0,07324368 0,08244151 GO:0070279|vitamin B6 binding, ! exonuclease activity GO:0004527 79 49 0,000 0,07324368 0,08241608 ! maintenance of location GO:0051235 62 49 0,000 0,07324368 0,08239067 ! negative regulation of cell motion GO:0051271 60 49 0,000 0,07324368 0,08236527 ! regulation of actin filament length GO:0030832 62 49 0,000 0,07324368 0,08233989 ! nuclear periphery GO:0034399 60 49 0,000 0,07324368 0,08231452 ! regulation of muscle contraction GO:0006937 57 49 0,000 0,07324368 0,08228917 ! negative regulation of cytoskeleton organization GO:0051494 73 49 0,000 0,07324368 0,08226383 ! nucleotide-excision repair GO:0006289 53 49 0,000 0,07324368 0,08223852 ! DNA damage response, signal transduction GO:0042770 84 50 0,000 0,07468313 0,08382894 ! cytokine-mediated signaling pathway GO:0019221 56 50 0,000 0,07468313 0,08380315 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,07468313 0,08377738 ! embryonic skeletal system development GO:0048706 59 50 0,000 0,07468313 0,08375163 ! generation of a signal involved in cell-cell signaling GO:0003001 59 50 0,000 0,07468313 0,08372589 ! heart morphogenesis GO:0003007 57 50 0,000 0,07468313 0,08370017 ! integrin binding GO:0005178 56 50 0,000 0,07468313 0,08367446 ! detection of abiotic stimulus GO:0009582 56 50 0,000 0,07468313 0,08364877 ! regulation of angiogenesis GO:0045765 56 51 0,000 0,07612041 0,08523243 ! positive regulation of cell migration GO:0030335 63 51 0,000 0,07612041 0,08520628 ! regulation of ossification GO:0030278 59 51 0,000 0,07612041 0,08518014 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 60 51 0,000 0,07612041 0,08515402 ! positive regulation of organelle organization GO:0010638 69 51 0,000 0,07612041 0,08512792 ! cellular polysaccharide metabolic process GO:0044264 65 51 0,000 0,07612041 0,08510183 ! endocrine system development GO:0035270 55 51 0,000 0,07612041 0,08507576 ! germ cell development GO:0007281 56 51 0,000 0,07612041 0,0850497 ! transferase activity, transferring sulfur-containing groups GO:0016782 60 52 0,000 0,07755555 0,08662665 ! regulation of cellular component size GO:0032535 66 52 0,000 0,07755555 0,08660013 ! carbohydrate transport GO:0008643 57 52 0,000 0,07755555 0,08657364 ! ubiquitin thiolesterase activity GO:0004221 64 52 0,000 0,07755555 0,08654715 ! nucleoside monophosphate metabolic process GO:0009123 58 52 0,000 0,07755555 0,08652068 ! cell maturation GO:0048469 68 52 0,000 0,07755555 0,08649423 ! regulation of intracellular transport GO:0032386 57 52 0,000 0,07755555 0,0864678 ! kidney development GO:0001822 55 52 0,000 0,07755555 0,08644138 ! cellular component disassembly GO:0022411 69 52 0,000 0,07755555 0,08641498 ! cell redox homeostasis GO:0045454 57 52 0,000 0,07755555 0,08638859 ! lipoprotein biosynthetic process GO:0042158 57 52 0,000 0,07755555 0,08636222 ! lipid transporter activity GO:0005319 58 52 0,000 0,07755555 0,08633587 ! cytokine receptor activity GO:0004896 54 52 0,000 0,07755555 0,08630953 ! antiporter activity GO:0015297 53 52 0,000 0,07755555 0,08628321 ! embryonic limb morphogenesis GO:0030326 62 53 0,000 0,07898853 0,08785066 GO:0035113|embryonic appendage morphogenesis, ! glycosaminoglycan metabolic process GO:0030203 60 53 0,000 0,07898853 0,08782388 ! keratinocyte differentiation GO:0030216 60 53 0,000 0,07898853 0,08779712 ! basement membrane GO:0005604 55 53 0,000 0,07898853 0,08777038 ! water-soluble vitamin metabolic process GO:0006767 59 53 0,000 0,07898853 0,08774365 ! negative regulation of response to stimulus GO:0048585 68 53 0,000 0,07898853 0,08771694 ! viral reproduction GO:0016032 59 53 0,000 0,07898853 0,08769025 ! chloride transport GO:0006821 60 53 0,000 0,07898853 0,08766357 ! oxygen and reactive oxygen species metabolic process GO:0006800 58 53 0,000 0,07898853 0,08763691 ! regulation of protein catabolic process GO:0042176 56 53 0,000 0,07898853 0,08761026 ! regulation of DNA replication GO:0006275 75 53 0,000 0,07898853 0,08758363 ! DNA catabolic process GO:0006308 57 53 0,000 0,07898853 0,08755702 ! heterocycle catabolic process GO:0046700 56 53 0,000 0,07898853 0,08753042 ! integrin-mediated signaling pathway GO:0007229 59 53 0,000 0,07898853 0,08750384 ! single fertilization GO:0007338 58 53 0,000 0,07898853 0,08747728 ! activation of phospholipase C activity GO:0007202 61 54 0,000 0,08041936 0,08903485 GO:0010863|positive regulation of phospholipase C activity, ! double-stranded DNA binding GO:0003690 63 54 0,000 0,08041936 0,08900784 ! nucleoside metabolic process GO:0009116 62 54 0,000 0,08041936 0,08898084 ! coated membrane GO:0048475 65 54 0,000 0,08041936 0,08895386 GO:0030117|membrane coat, ! nucleosome GO:0000786 59 54 0,000 0,08041936 0,0889269 ! regulation of protein complex assembly GO:0043254 67 54 0,000 0,08041936 0,08889995 ! cellular defense response GO:0006968 61 54 0,000 0,08041936 0,08887302 ! gastrulation GO:0007369 62 54 0,000 0,08041936 0,0888461 ! dendrite GO:0030425 60 55 0,000 0,08184805 0,09039712 ! regulation of mitosis GO:0007088 79 55 0,000 0,08184805 0,09036976 GO:0051783|regulation of nuclear division, ! positive regulation of phospholipase activity GO:0010518 62 55 0,000 0,08184805 0,09034241 ! coenzyme biosynthetic process GO:0009108 68 55 0,000 0,08184805 0,09031509 ! extracellular matrix organization GO:0030198 77 55 0,000 0,08184805 0,09028777 ! positive regulation of cell motion GO:0051272 69 55 0,000 0,08184805 0,09026048 ! protein amino acid autophosphorylation GO:0046777 61 55 0,000 0,08184805 0,0902332 ! translation initiation factor activity GO:0003743 66 55 0,000 0,08184805 0,09020594 ! steroid hormone receptor signaling pathway GO:0030518 70 55 0,000 0,08184805 0,0901787 ! regulation of bone remodeling GO:0046850 64 56 0,000 0,08327459 0,09172273 ! heat shock protein binding GO:0031072 62 56 0,000 0,08327459 0,09169505 ! late endosome GO:0005770 60 56 0,000 0,08327459 0,09166738 ! regulation of phospholipase activity GO:0010517 63 56 0,000 0,08327459 0,09163973 ! sphingolipid metabolic process GO:0006665 60 56 0,000 0,08327459 0,09161209 ! intrinsic to endoplasmic reticulum membrane GO:0031227 61 56 0,000 0,08327459 0,09158447 ! ribonuclease activity GO:0004540 67 56 0,000 0,08327459 0,09155687 ! positive regulation of T cell activation GO:0050870 74 56 0,000 0,08327459 0,09152929 ! mesoderm development GO:0007498 67 56 0,000 0,08327459 0,09150172 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 61 56 0,000 0,08327459 0,09147416 ! antigen processing and presentation GO:0019882 73 56 0,000 0,08327459 0,09144663 ! proton transport GO:0015992 59 56 0,000 0,08327459 0,09141911 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 57 0,000 0,08469899 0,09295485 ! chromosome segregation GO:0007059 92 57 0,000 0,08469899 0,09292689 ! glycerophospholipid biosynthetic process GO:0046474 71 57 0,000 0,08469899 0,09289895 ! B cell activation GO:0042113 63 57 0,000 0,08469899 0,09287103 ! small ribosomal subunit GO:0015935 58 57 0,000 0,08469899 0,09284312 ! detection of external stimulus GO:0009581 64 57 0,000 0,08469899 0,09281523 ! occluding junction GO:0070160 75 58 0,000 0,08612125 0,09434545 GO:0005923|tight junction, ! epidermal cell differentiation GO:0009913 66 58 0,000 0,08612125 0,09431712 ! hydrogen transport GO:0006818 61 58 0,000 0,08612125 0,09428882 ! receptor signaling protein serine/threonine kinase activity GO:0004702 64 58 0,000 0,08612125 0,09426053 ! lymphocyte mediated immunity GO:0002449 65 58 0,000 0,08612125 0,09423225 ! response to nutrient GO:0007584 68 58 0,000 0,08612125 0,094204 ! large ribosomal subunit GO:0015934 64 58 0,000 0,08612125 0,09417576 ! regulation of tissue remodeling GO:0034103 66 58 0,000 0,08612125 0,09414754 ! ligand-dependent nuclear receptor activity GO:0004879 72 58 0,000 0,08612125 0,09411933 ! myosin complex GO:0016459 64 58 0,000 0,08612125 0,09409115 ! regulation of gene-specific transcription GO:0032583 69 59 0,000 0,08754139 0,09561406 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 62 59 0,000 0,08754139 0,09558545 GO:0051213|dioxygenase activity, ! muscle cell differentiation GO:0042692 77 59 0,000 0,08754139 0,09555684 ! regulation of heart contraction GO:0008016 71 59 0,000 0,08754139 0,09552826 ! cellular amino acid catabolic process GO:0009063 63 59 0,000 0,08754139 0,09549969 ! response to steroid hormone stimulus GO:0048545 74 59 0,000 0,08754139 0,09547114 ! cell projection assembly GO:0030031 79 59 0,000 0,08754139 0,09544261 ! regulation of cellular response to stress GO:0080135 79 59 0,000 0,08754139 0,09541409 ! appendage morphogenesis GO:0035107 68 59 0,000 0,08754139 0,0953856 GO:0035108|limb morphogenesis, ! homeostasis of number of cells GO:0048872 67 59 0,000 0,08754139 0,09535711 ! fertilization GO:0009566 65 59 0,000 0,08754139 0,09532865 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 62 59 0,000 0,08754139 0,0953002 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 69 59 0,000 0,08754139 0,09527177 ! adult behavior GO:0030534 72 59 0,000 0,08754139 0,09524336 ! organelle localization GO:0051640 70 59 0,000 0,08754139 0,09521496 ! positive regulation of secretion GO:0051047 66 60 0,000 0,08895939 0,09672842 ! molecular adaptor activity GO:0060090 73 60 0,000 0,08895939 0,09669959 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 63 60 0,000 0,08895939 0,09667079 ! phosphoinositide metabolic process GO:0030384 68 60 0,000 0,08895939 0,096642 ! copper ion binding GO:0005507 85 60 0,000 0,08895939 0,09661323 ! positive regulation of lipase activity GO:0060193 68 60 0,000 0,08895939 0,09658448 ! activation of immune response GO:0002253 72 60 0,000 0,08895939 0,09655574 ! cell cycle checkpoint GO:0000075 91 60 0,000 0,08895939 0,09652702 ! regulation of caspase activity GO:0043281 78 60 0,000 0,08895939 0,09649832 ! appendage development GO:0048736 69 60 0,000 0,08895939 0,09646963 GO:0060173|limb development, ! regulation of vesicle-mediated transport GO:0060627 69 60 0,000 0,08895939 0,09644096 ! secondary metabolic process GO:0019748 67 60 0,000 0,08895939 0,09641231 ! cellular hormone metabolic process GO:0034754 64 61 0,000 0,09037526 0,09791771 ! ear development GO:0043583 76 61 0,000 0,09037526 0,09788864 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 68 61 0,000 0,09037526 0,09785958 ! learning or memory GO:0007611 79 61 0,000 0,09037526 0,09783055 ! Ras GTPase binding GO:0017016 78 61 0,000 0,09037526 0,09780153 ! camera-type eye development GO:0043010 69 61 0,000 0,09037526 0,09777252 ! transcription initiation from RNA polymerase II promoter GO:0006367 69 61 0,000 0,09037526 0,09774353 ! regulation of transcription factor activity GO:0051090 80 62 0,000 0,09178901 0,09924312 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 90 62 0,000 0,09178901 0,09921372 ! lysosomal membrane GO:0005765 69 62 0,000 0,09178901 0,09918433 ! membrane lipid metabolic process GO:0006643 76 62 0,000 0,09178901 0,09915496 ! nuclear pore GO:0005643 79 62 0,000 0,09178901 0,0991256 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 77 62 0,000 0,09178901 0,09909627 ! skeletal system morphogenesis GO:0048705 83 62 0,000 0,09178901 0,09906695 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 77 62 0,000 0,09178901 0,09903765 ! chloride channel activity GO:0005254 72 62 0,000 0,09178901 0,09900837 ! cell soma GO:0043025 68 62 0,000 0,09178901 0,0989791 ! microtubule motor activity GO:0003777 94 62 0,000 0,09178901 0,09894985 ! intracellular receptor-mediated signaling pathway GO:0030522 80 62 0,000 0,09178901 0,09892062 ! focal adhesion GO:0005925 72 62 0,000 0,09178901 0,0988914 ! protein maturation by peptide bond cleavage GO:0051605 69 62 0,000 0,09178901 0,09886221 ! FAD binding GO:0050660 71 63 0,000 0,09320063 0,10035298 ! regulation of endopeptidase activity GO:0052548 81 63 0,000 0,09320063 0,10032337 ! urogenital system development GO:0001655 75 63 0,000 0,09320063 0,10029378 ! regulation of synaptic transmission GO:0050804 79 63 0,000 0,09320063 0,1002642 ! aminoglycan metabolic process GO:0006022 70 63 0,000 0,09320063 0,10023464 ! cAMP-mediated signaling GO:0019933 75 63 0,000 0,09320063 0,1002051 ! amine transmembrane transporter activity GO:0005275 69 63 0,000 0,09320063 0,10017558 ! regulation of immune effector process GO:0002697 81 63 0,000 0,09320063 0,10014607 ! respiratory tube development GO:0030323 92 64 0,000 0,09461014 0,10163068 ! intracellular protein transmembrane transport GO:0065002 83 64 0,000 0,09461014 0,10160076 ! tRNA processing GO:0008033 73 64 0,000 0,09461014 0,10157086 ! negative regulation of ligase activity GO:0051352 79 64 0,000 0,09461014 0,10154098 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of myeloid cell differentiation GO:0045637 77 64 0,000 0,09461014 0,10151111 ! adaptive immune response GO:0002250 70 64 0,000 0,09461014 0,10148127 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! transition metal ion transport GO:0000041 74 64 0,000 0,09461014 0,10145144 ! neurotransmitter transport GO:0006836 72 64 0,000 0,09461014 0,10142162 ! regulation of actin cytoskeleton organization GO:0032956 93 64 0,000 0,09461014 0,10139183 ! nuclear hormone receptor binding GO:0035257 79 64 0,000 0,09461014 0,10136205 ! multicellular organism reproduction GO:0032504 71 65 0,000 0,09601753 0,10283968 GO:0048609|reproductive process in a multicellular organism, ! lymphocyte differentiation GO:0030098 93 65 0,000 0,09601753 0,1028095 ! regulation of cytokine biosynthetic process GO:0042035 84 65 0,000 0,09601753 0,10277933 ! activation of MAPK activity GO:0000187 74 65 0,000 0,09601753 0,10274918 ! gonad development GO:0008406 71 65 0,000 0,09601753 0,10271905 ! protein import into nucleus GO:0006606 73 66 0,000 0,09742281 0,10419185 ! developmental maturation GO:0021700 85 66 0,000 0,09742281 0,10416132 ! myeloid cell differentiation GO:0030099 78 66 0,000 0,09742281 0,1041308 ! tubulin binding GO:0015631 92 66 0,000 0,09742281 0,1041003 ! leukocyte mediated immunity GO:0002443 73 66 0,000 0,09742281 0,10406981 ! tube morphogenesis GO:0035239 84 66 0,000 0,09742281 0,10403935 ! cysteine-type endopeptidase activity GO:0004197 73 66 0,000 0,09742281 0,1040089 ! cell-substrate adherens junction GO:0005924 76 66 0,000 0,09742281 0,10397847 ! regulation of peptidase activity GO:0052547 86 67 0,000 0,09882598 0,10544521 ! endoplasmic reticulum lumen GO:0005788 78 67 0,000 0,09882598 0,10541438 ! glycerolipid biosynthetic process GO:0045017 81 67 0,000 0,09882598 0,10538357 ! nuclear import GO:0051170 74 67 0,000 0,09882598 0,10535277 ! response to peptide hormone stimulus GO:0043434 79 67 0,000 0,09882598 0,10532199 ! activation of protein kinase activity GO:0032147 83 67 0,000 0,09882598 0,10529123 ! regulation of actin filament-based process GO:0032970 96 67 0,000 0,09882598 0,10526049 ! chloride ion binding GO:0031404 79 67 0,000 0,09882598 0,10522977 ! humoral immune response GO:0006959 75 67 0,000 0,09882598 0,10519906 ! amine binding GO:0043176 77 67 0,000 0,09882598 0,10516837 ! female pregnancy GO:0007565 78 67 0,000 0,09882598 0,1051377 ! extrinsic to membrane GO:0019898 75 67 0,000 0,09882598 0,10510705 ! anion channel activity GO:0005253 77 67 0,000 0,09882598 0,10507641 ! regulation of homeostatic process GO:0032844 88 67 0,000 0,09882598 0,1050458 ! amine catabolic process GO:0009310 73 68 0,000 0,10022705 0,10650401 ! negative regulation of organelle organization GO:0010639 93 68 0,000 0,10022705 0,10647299 ! cell-substrate junction GO:0030055 78 68 0,000 0,10022705 0,106442 ! respiratory system development GO:0060541 96 68 0,000 0,10022705 0,10641102 ! mRNA transport GO:0051028 88 69 0,000 0,10162601 0,1078649 ! fatty acid biosynthetic process GO:0006633 76 69 0,000 0,10162601 0,10783353 ! small GTPase binding GO:0031267 86 69 0,000 0,10162601 0,10780217 ! regulation of transmission of nerve impulse GO:0051969 87 69 0,000 0,10162601 0,10777083 ! sarcomere GO:0030017 74 69 0,000 0,10162601 0,10773951 ! exocytosis GO:0006887 76 69 0,000 0,10162601 0,10770821 ! skeletal muscle tissue development GO:0007519 75 69 0,000 0,10162601 0,10767693 GO:0060538|skeletal muscle organ development, ! nucleosome assembly GO:0006334 87 69 0,000 0,10162601 0,10764566 ! extracellular ligand-gated ion channel activity GO:0005230 82 69 0,000 0,10162601 0,10761442 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 79 69 0,000 0,10162601 0,10758319 ! amine biosynthetic process GO:0009309 78 70 0,000 0,10302287 0,10903029 ! thiolester hydrolase activity GO:0016790 84 70 0,000 0,10302287 0,10899867 ! early endosome GO:0005769 104 70 0,000 0,10302287 0,10896707 ! regulation of lipase activity GO:0060191 78 70 0,000 0,10302287 0,10893548 ! amino acid transport GO:0006865 76 70 0,000 0,10302287 0,10890392 ! chromatin assembly GO:0031497 88 70 0,000 0,10302287 0,10887237 ! hormone receptor binding GO:0051427 85 70 0,000 0,10302287 0,10884084 ! calcium channel activity GO:0005262 86 70 0,000 0,10302287 0,10880933 ! axon guidance GO:0007411 87 70 0,000 0,10302287 0,10877783 ! nuclear chromosome part GO:0044454 94 70 0,000 0,10302287 0,10874636 ! mitochondrial outer membrane GO:0005741 81 71 0,000 0,10441763 0,11018673 ! protein localization in nucleus GO:0034504 78 71 0,000 0,10441763 0,11015486 ! lipoprotein metabolic process GO:0042157 76 71 0,000 0,10441763 0,11012302 ! pore complex GO:0046930 89 72 0,000 0,1058103 0,11155953 ! response to hypoxia GO:0001666 84 72 0,000 0,1058103 0,1115273 ! steroid biosynthetic process GO:0006694 83 72 0,000 0,1058103 0,11149508 ! regulation of MAPKKK cascade GO:0043408 82 72 0,000 0,1058103 0,11146289 ! acute inflammatory response GO:0002526 91 72 0,000 0,1058103 0,11143071 ! apical junction complex GO:0043296 90 72 0,000 0,1058103 0,11139855 ! phospholipase activity GO:0004620 99 72 0,000 0,1058103 0,11136641 ! membrane raft GO:0045121 81 72 0,000 0,1058103 0,11133429 ! regulation of neurological system process GO:0031644 91 72 0,000 0,1058103 0,11130218 ! structural constituent of cytoskeleton GO:0005200 78 72 0,000 0,1058103 0,1112701 ! elevation of cytosolic calcium ion concentration GO:0007204 87 73 0,000 0,10720088 0,11269994 GO:0051480|cytosolic calcium ion homeostasis, ! response to drug GO:0042493 94 73 0,000 0,10720088 0,11266747 ! protein transporter activity GO:0008565 80 73 0,000 0,10720088 0,11263502 ! exopeptidase activity GO:0008238 81 73 0,000 0,10720088 0,11260259 ! digestion GO:0007586 81 73 0,000 0,10720088 0,11257018 ! regulation of Rho protein signal transduction GO:0035023 88 73 0,000 0,10720088 0,11253778 ! cell-matrix adhesion GO:0007160 102 74 0,000 0,10858937 0,1139626 ! response to oxygen levels GO:0070482 86 74 0,000 0,10858937 0,11392983 ! potassium channel complex GO:0034705 84 74 0,000 0,10858937 0,11389707 GO:0008076|voltage-gated potassium channel complex, ! GTPase binding GO:0051020 91 74 0,000 0,10858937 0,11386433 ! protein-DNA complex assembly GO:0065004 101 74 0,000 0,10858937 0,11383161 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 85 74 0,000 0,10858937 0,11379891 ! one-carbon metabolic process GO:0006730 84 74 0,000 0,10858937 0,11376623 ! blood coagulation GO:0007596 90 74 0,000 0,10858937 0,11373357 GO:0050817|coagulation, ! reproductive structure development GO:0048608 89 74 0,000 0,10858937 0,11370092 ! apicolateral plasma membrane GO:0016327 92 74 0,000 0,10858937 0,1136683 ! phosphoinositide-mediated signaling GO:0048015 92 74 0,000 0,10858937 0,11363569 ! cellular lipid catabolic process GO:0044242 99 74 0,000 0,10858937 0,1136031 ! ubiquitin ligase complex GO:0000151 91 74 0,000 0,10858937 0,11357053 ! cell projection part GO:0044463 80 74 0,000 0,10858937 0,11353798 ! meiosis GO:0007126 108 75 0,000 0,10997577 0,11495462 GO:0051327|M phase of meiotic cell cycle, ! regulation of DNA binding GO:0051101 94 75 0,000 0,10997577 0,11492169 ! carboxylic acid transmembrane transporter activity GO:0046943 85 75 0,000 0,10997577 0,11488878 ! regulation of cell cycle process GO:0010564 113 75 0,000 0,10997577 0,11485589 ! regulation of blood pressure GO:0008217 82 75 0,000 0,10997577 0,11482302 ! transcription initiation GO:0006352 84 75 0,000 0,10997577 0,11479016 ! Ras GTPase activator activity GO:0005099 83 75 0,000 0,10997577 0,11475733 ! neuropeptide signaling pathway GO:0007218 85 76 0,000 0,1113601 0,11616861 ! defense response to bacterium GO:0042742 81 76 0,000 0,1113601 0,1161354 ! regulation of lipid metabolic process GO:0019216 98 76 0,000 0,1113601 0,11610221 ! cell leading edge GO:0031252 97 76 0,000 0,1113601 0,11606904 ! meiotic cell cycle GO:0051321 109 76 0,000 0,1113601 0,11603588 ! regulation of neuron differentiation GO:0045664 96 76 0,000 0,1113601 0,11600275 ! protein-DNA complex GO:0032993 93 76 0,000 0,1113601 0,11596963 ! organic acid transmembrane transporter activity GO:0005342 86 76 0,000 0,1113601 0,11593654 ! development of primary sexual characteristics GO:0045137 86 76 0,000 0,1113601 0,11590346 ! cytosolic ribosome GO:0022626 82 76 0,000 0,1113601 0,1158704 ! serine-type endopeptidase inhibitor activity GO:0004867 93 76 0,000 0,1113601 0,11583736 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 84 77 0,000 0,11274234 0,11724175 ! nucleosome organization GO:0034728 96 77 0,000 0,11274234 0,11720834 ! vacuolar membrane GO:0005774 86 77 0,000 0,11274234 0,11717494 ! G-protein-coupled receptor binding GO:0001664 87 77 0,000 0,11274234 0,11714157 ! regulation of Ras GTPase activity GO:0032318 88 77 0,000 0,11274234 0,11710822 ! establishment of RNA localization GO:0051236 97 77 0,000 0,11274234 0,11707488 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! myofibril GO:0030016 82 77 0,000 0,11274234 0,11704156 ! protein oligomerization GO:0051259 93 77 0,000 0,11274234 0,11700827 ! phosphoric diester hydrolase activity GO:0008081 99 78 0,000 0,11412251 0,11840697 ! endonuclease activity GO:0004519 111 78 0,000 0,11412251 0,1183733 ! cofactor biosynthetic process GO:0051188 93 78 0,000 0,11412251 0,11833966 ! inorganic anion transport GO:0015698 87 78 0,000 0,11412251 0,11830603 ! regulation of protein transport GO:0051223 85 78 0,000 0,11412251 0,11827242 ! transmembrane receptor protein kinase activity GO:0019199 95 78 0,000 0,11412251 0,11823883 ! carboxylesterase activity GO:0004091 93 78 0,000 0,11412251 0,11820525 ! protein ubiquitination GO:0016567 95 78 0,000 0,11412251 0,1181717 ! extracellular matrix structural constituent GO:0005201 96 78 0,000 0,11412251 0,11813817 ! contractile fiber part GO:0044449 83 78 0,000 0,11412251 0,11810465 ! RNA localization GO:0006403 99 79 0,000 0,1155006 0,11949694 ! positive regulation of MAP kinase activity GO:0043406 89 79 0,000 0,1155006 0,11946306 ! vitamin metabolic process GO:0006766 86 79 0,000 0,1155006 0,11942919 ! T cell activation GO:0042110 120 79 0,000 0,1155006 0,11939535 ! cellular response to hormone stimulus GO:0032870 94 79 0,000 0,1155006 0,11936153 ! phosphoinositide binding GO:0035091 99 79 0,000 0,1155006 0,11932773 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 88 80 0,000 0,11687663 0,12071516 ! ATP biosynthetic process GO:0006754 89 80 0,000 0,11687663 0,12068099 ! rhythmic process GO:0048511 90 80 0,000 0,11687663 0,12064684 ! regulation of catabolic process GO:0009894 87 80 0,000 0,11687663 0,12061271 ! SH3 domain binding GO:0017124 95 80 0,000 0,11687663 0,1205786 ! hemostasis GO:0007599 96 80 0,000 0,11687663 0,12054451 ! cell-substrate adhesion GO:0031589 109 80 0,000 0,11687663 0,12051044 ! rRNA processing GO:0006364 84 80 0,000 0,11687663 0,12047639 ! cholesterol metabolic process GO:0008203 91 81 0,000 0,11825059 0,12185823 ! vacuolar part GO:0044437 91 81 0,000 0,11825059 0,12182382 ! ossification GO:0001503 111 82 0,000 0,11962248 0,12320237 ! biogenic amine metabolic process GO:0006576 99 82 0,000 0,11962248 0,1231676 ! forebrain development GO:0030900 93 82 0,000 0,11962248 0,12313285 ! external side of plasma membrane GO:0009897 105 82 0,000 0,11962248 0,12309811 ! heparin binding GO:0008201 108 82 0,000 0,11962248 0,1230634 ! microtubule-based movement GO:0007018 119 83 0,000 0,12099231 0,12443754 ! nuclear speck GO:0016607 99 83 0,000 0,12099231 0,12440247 ! rRNA metabolic process GO:0016072 88 83 0,000 0,12099231 0,12436742 ! ATP-dependent helicase activity GO:0008026 107 83 0,000 0,12099231 0,12433238 GO:0070035|purine NTP-dependent helicase activity, ! regulation of cell adhesion GO:0030155 98 83 0,000 0,12099231 0,12429737 ! regulation of T cell activation GO:0050863 104 83 0,000 0,12099231 0,12426238 ! regulation of establishment of protein localization GO:0070201 90 83 0,000 0,12099231 0,1242274 ! contractile fiber GO:0043292 88 83 0,000 0,12099231 0,12419245 ! bone development GO:0060348 112 83 0,000 0,12099231 0,12415751 ! regulation of membrane potential GO:0042391 98 83 0,000 0,12099231 0,1241226 ! cilium GO:0005929 88 83 0,000 0,12099231 0,1240877 ! regulation of DNA metabolic process GO:0051052 139 84 0,000 0,12236009 0,1254552 ! regulation of defense response GO:0031347 98 84 0,000 0,12236009 0,12541995 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 94 84 0,000 0,12236009 0,12538472 ! nitrogen compound catabolic process GO:0044270 91 84 0,000 0,12236009 0,12534951 ! DNA recombination GO:0006310 147 84 0,000 0,12236009 0,12531432 ! phospholipid biosynthetic process GO:0008654 101 85 0,000 0,12372581 0,12667745 ! protein modification by small protein conjugation GO:0032446 103 85 0,000 0,12372581 0,1266419 ! monooxygenase activity GO:0004497 92 85 0,000 0,12372581 0,12660638 ! hydrogen ion transmembrane transporter activity GO:0015078 88 85 0,000 0,12372581 0,12657088 ! protein binding, bridging GO:0030674 104 85 0,000 0,12372581 0,12653539 ! negative regulation of transport GO:0051051 98 86 0,000 0,12508948 0,12789417 ! clathrin-coated vesicle GO:0030136 100 86 0,000 0,12508948 0,12785834 ! lipase activity GO:0016298 114 86 0,000 0,12508948 0,12782252 ! voltage-gated potassium channel activity GO:0005249 105 86 0,000 0,12508948 0,12778673 ! adherens junction GO:0005912 100 86 0,000 0,12508948 0,12775095 ! microtubule cytoskeleton organization GO:0000226 113 87 0,000 0,12645109 0,1291054 ! leukocyte differentiation GO:0002521 118 87 0,000 0,12645109 0,12906928 ! regulation of cell morphogenesis GO:0022604 100 87 0,000 0,12645109 0,12903317 ! organelle outer membrane GO:0031968 102 88 0,000 0,12781067 0,13038404 ! carbohydrate biosynthetic process GO:0016051 95 88 0,000 0,12781067 0,13034759 ! growth factor binding GO:0019838 102 88 0,000 0,12781067 0,13031116 ! protein processing GO:0016485 100 88 0,000 0,12781067 0,13027475 ! gland development GO:0048732 108 89 0,000 0,1291682 0,13162167 ! ATP metabolic process GO:0046034 100 90 0,000 0,13052369 0,13296577 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 101 90 0,000 0,13052369 0,13292865 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! peroxisome GO:0005777 100 90 0,000 0,13052369 0,13289155 GO:0042579|microbody, ! glycerophospholipid metabolic process GO:0006650 109 90 0,000 0,13052369 0,13285447 ! sterol metabolic process GO:0016125 102 90 0,000 0,13052369 0,13281741 ! negative regulation of multicellular organismal process GO:0051241 102 90 0,000 0,13052369 0,13278037 ! anion binding GO:0043168 104 90 0,000 0,13052369 0,13274335 ! amine transport GO:0015837 97 90 0,000 0,13052369 0,13270636 ! outer membrane GO:0019867 104 90 0,000 0,13052369 0,13266938 ! extracellular matrix part GO:0044420 111 90 0,000 0,13052369 0,13263243 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 108 91 0,000 0,13187714 0,13397043 ! ribonucleoside triphosphate biosynthetic process GO:0009201 102 91 0,000 0,13187714 0,13393313 GO:0009142|nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 104 91 0,000 0,13187714 0,13389585 ! sulfur metabolic process GO:0006790 98 91 0,000 0,13187714 0,1338586 ! sex differentiation GO:0007548 103 91 0,000 0,13187714 0,13382136 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 112 91 0,000 0,13187714 0,13378415 ! hormone metabolic process GO:0042445 107 91 0,000 0,13187714 0,13374696 ! regulation of protein localization GO:0032880 99 91 0,000 0,13187714 0,13370978 ! detection of stimulus GO:0051606 100 91 0,000 0,13187714 0,13367263 ! structure-specific DNA binding GO:0043566 112 92 0,000 0,13322856 0,13500494 ! anatomical structure homeostasis GO:0060249 121 92 0,000 0,13322856 0,13496745 ! regulation of cellular component biogenesis GO:0044087 115 92 0,000 0,13322856 0,13492998 ! carboxylic acid catabolic process GO:0046395 100 92 0,000 0,13322856 0,13489253 GO:0016054|organic acid catabolic process, ! translation factor activity, nucleic acid binding GO:0008135 108 92 0,000 0,13322856 0,1348551 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 111 92 0,000 0,13322856 0,13481769 ! regulation of GTPase activity GO:0043087 105 92 0,000 0,13322856 0,1347803 ! extracellular structure organization GO:0043062 119 92 0,000 0,13322856 0,13474294 ! protein import GO:0017038 102 93 0,000 0,13457794 0,13606994 ! regulation of cytoskeleton organization GO:0051493 133 93 0,000 0,13457794 0,13603223 ! neurotransmitter receptor activity GO:0030594 104 93 0,000 0,13457794 0,13599455 ! response to nutrient levels GO:0031667 105 93 0,000 0,13457794 0,13595689 ! protein modification by small protein conjugation or removal GO:0070647 112 93 0,000 0,13457794 0,13591925 ! ATPase activity, coupled to transmembrane movement of substances GO:0042626 102 94 0,000 0,1359253 0,13724204 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 104 94 0,000 0,1359253 0,13720407 ! morphogenesis of an epithelium GO:0002009 113 94 0,000 0,1359253 0,13716611 GO:0060429|epithelium development, ! anchoring junction GO:0070161 108 94 0,000 0,1359253 0,13712818 ! neurotransmitter binding GO:0042165 105 94 0,000 0,1359253 0,13709027 ! DNA packaging GO:0006323 113 94 0,000 0,1359253 0,13705238 ! homophilic cell adhesion GO:0007156 107 95 0,000 0,13727063 0,13837062 ! ATPase activity, coupled to movement of substances GO:0043492 104 95 0,000 0,13727063 0,1383324 ! anterior/posterior pattern formation GO:0009952 109 95 0,000 0,13727063 0,13829419 ! protein localization in organelle GO:0033365 104 95 0,000 0,13727063 0,13825601 ! Wnt receptor signaling pathway GO:0016055 121 95 0,000 0,13727063 0,13821785 ! immune effector process GO:0002252 110 95 0,000 0,13727063 0,13817971 ! apical plasma membrane GO:0016324 105 95 0,000 0,13727063 0,13814159 ! translational elongation GO:0006414 104 96 0,000 0,13861394 0,13945495 ! hydrolase activity, acting on glycosyl bonds GO:0016798 109 96 0,000 0,13861394 0,13941651 ! in utero embryonic development GO:0001701 110 96 0,000 0,13861394 0,13937808 ! receptor complex GO:0043235 131 96 0,000 0,13861394 0,13933967 ! regulation of response to external stimulus GO:0032101 109 96 0,000 0,13861394 0,13930129 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 100 96 0,000 0,13861394 0,13926292 ! microtubule associated complex GO:0005875 135 97 0,000 0,13995523 0,14057178 ! metalloendopeptidase activity GO:0004222 126 97 0,000 0,13995523 0,14053308 ! perinuclear region of cytoplasm GO:0048471 125 97 0,000 0,13995523 0,14049441 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances GO:0016820 105 97 0,000 0,13995523 0,14045576 ! carboxylic acid binding GO:0031406 108 97 0,000 0,13995523 0,14041713 ! protein maturation GO:0051604 109 97 0,000 0,13995523 0,14037852 ! intermediate filament GO:0005882 102 98 0,000 0,14129451 0,14168289 GO:0045111|intermediate filament cytoskeleton, ! UDP-glycosyltransferase activity GO:0008194 120 98 0,000 0,14129451 0,14164396 ! cell fate commitment GO:0045165 118 98 0,000 0,14129451 0,14160505 ! negative regulation of cellular component organization GO:0051129 132 99 0,000 0,14263177 0,14290598 ! hormone activity GO:0005179 113 99 0,000 0,14263177 0,14286675 ! solute:cation symporter activity GO:0015294 110 99 0,000 0,14263177 0,14282753 ! unfolded protein binding GO:0051082 118 100 0,000 0,14396702 0,14412505 ! nuclear chromosome GO:0000228 127 100 0,000 0,14396702 0,14408551 ! regulation of neurogenesis GO:0050767 123 100 0,000 0,14396702 0,14404599 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016810 105 100 0,000 0,14396702 0,14400649 ! peptide receptor activity, G-protein coupled GO:0008528 107 100 0,000 0,14396702 0,14396702