pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/374291-4-real-Ivshina_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! polyol catabolic process GO:0046174 7 5 2,000 2,166E-08 5,212E-05 GO:0019405|alditol catabolic process, ! cellular carbohydrate catabolic process GO:0044275 15 13 2,000 6,15E-07 7,399E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 1,001E-06 8,03E-04 ! fructose metabolic process GO:0006000 25 16 2,000 1,201E-06 7,223E-04 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 2,000 2,436E-06 1,172E-03 ! alditol metabolic process GO:0019400 38 24 2,000 4,308E-06 1,728E-03 ! sperm motility GO:0030317 31 25 2,000 4,891E-06 1,681E-03 ! osteoblast differentiation GO:0001649 60 25 2,000 4,891E-06 1,471E-03 ! alcohol catabolic process GO:0046164 130 86 3,000 5,235E-06 1,4E-03 ! hexose biosynthetic process GO:0019319 48 32 2,000 1,048E-05 2,522E-03 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 2,000 1,503E-05 3,288E-03 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! monosaccharide biosynthetic process GO:0046364 52 36 2,000 1,503E-05 3,014E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 1,716E-05 3,175E-03 ! polyol metabolic process GO:0019751 66 41 2,000 2,234E-05 3,839E-03 ! alcohol biosynthetic process GO:0046165 59 42 2,000 2,404E-05 3,855E-03 ! photoreceptor cell development GO:0042461 10 6 1,000 2,571E-05 3,867E-03 GO:0046530|photoreceptor cell differentiation, ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 1,000 2,571E-05 3,639E-03 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 3,167E-05 4,233E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 4,792E-05 6,068E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 1,000 4,792E-05 5,764E-03 ! response to UV GO:0009411 104 53 2,000 4,855E-05 5,563E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 7,688E-05 8,408E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 7,688E-05 8,042E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 1,000 7,688E-05 7,707E-03 ! establishment of cell polarity GO:0030010 16 10 1,000 7,688E-05 7,399E-03 ! Golgi vesicle budding GO:0048194 22 11 1,000 9,388E-05 8,688E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,126E-04 0,01003085 ! regulation of adenylate cyclase activity GO:0045761 156 80 2,000 1,661E-04 0,01427336 ! regulation of cAMP biosynthetic process GO:0030817 161 82 2,000 1,787E-04 0,01482739 ! regulation of cyclase activity GO:0031279 159 82 2,000 1,787E-04 0,01433315 ! regulation of lyase activity GO:0051339 160 83 2,000 1,852E-04 0,01437772 ! regulation of cAMP metabolic process GO:0030814 168 84 2,000 1,919E-04 0,01443101 ! response to unfolded protein GO:0006986 131 85 2,000 1,988E-04 0,01449234 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 2,000 2,129E-04 0,0150673 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! membrane budding GO:0006900 37 17 1,000 2,31E-04 0,01587826 ! ossification GO:0001503 188 90 2,000 2,353E-04 0,0157287 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 2,000 2,353E-04 0,0153036 ! bone development GO:0060348 189 91 2,000 2,431E-04 0,01539471 ! response to protein stimulus GO:0051789 149 91 2,000 2,431E-04 0,01499997 ! regulation of nucleotide metabolic process GO:0006140 182 93 2,000 2,592E-04 0,01559319 ! carbohydrate biosynthetic process GO:0016051 141 93 2,000 2,592E-04 0,01521287 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 2,76E-04 0,01581138 ! cellular response to unfolded protein GO:0034620 33 19 1,000 2,899E-04 0,01622294 GO:0030968|endoplasmic reticulum unfolded protein response, ! cell-cell junction organization GO:0045216 35 19 1,000 2,899E-04 0,01585424 ! interphase GO:0051325 213 98 2,000 3,025E-04 0,01617127 ! cell cycle arrest GO:0007050 213 100 2,000 3,21E-04 0,01678777 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 3,555E-04 0,01819673 ! positive regulation of B cell activation GO:0050871 38 22 1,000 3,907E-04 0,01958293 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 4,66E-04 0,0228818 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 4,66E-04 0,02242417 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 5,061E-04 0,0238761 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 5,061E-04 0,02341695 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 5,478E-04 0,02486881 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 5,911E-04 0,02633881 ! fat cell differentiation GO:0045444 50 27 1,000 5,911E-04 0,02585992 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 6,361E-04 0,02732888 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 6,826E-04 0,02881406 ! eye morphogenesis GO:0048592 60 30 1,000 7,308E-04 0,03031446 ! regulation of B cell activation GO:0050864 50 30 1,000 7,308E-04 0,02980066 ! response to heat GO:0009408 50 30 1,000 7,308E-04 0,02930398 ! protein targeting to membrane GO:0006612 68 33 1,000 8,848E-04 0,03489786 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 1,000 1,053E-03 0,04086485 ! cell junction organization GO:0034330 86 36 1,000 1,053E-03 0,0402162 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 1,053E-03 0,03958783 ! establishment or maintenance of cell polarity GO:0007163 83 37 1,000 1,112E-03 0,04117157 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 1,173E-03 0,04276451 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glycolysis GO:0006096 65 45 1,000 1,642E-03 0,05897693 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 1,642E-03 0,05810962 ! ATP synthesis coupled electron transport GO:0042773 64 45 1,000 1,642E-03 0,05726745 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! response to calcium ion GO:0051592 81 47 1,000 1,79E-03 0,06153483 ! positive regulation of cell cycle GO:0045787 89 48 1,000 1,867E-03 0,06325283 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 1,867E-03 0,06237432 ! response to temperature stimulus GO:0009266 76 49 1,000 1,944E-03 0,06408399 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 1,944E-03 0,06321799 ! vesicle organization GO:0016050 107 51 1,000 2,105E-03 0,06751276 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 2,105E-03 0,06662443 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! respiratory electron transport chain GO:0022904 76 53 1,000 2,271E-03 0,07095244 ! regulation of translational initiation GO:0006446 82 53 1,000 2,271E-03 0,0700428 ! glucose catabolic process GO:0006007 82 55 1,000 2,443E-03 0,07440126 ! aging GO:0007568 103 55 1,000 2,443E-03 0,07347125 ! actin filament organization GO:0007015 148 66 1,000 3,496E-03 0,10385365 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 3,601E-03 0,10565518 ! negative regulation of cell growth GO:0030308 132 67 1,000 3,601E-03 0,10438222 ! hexose catabolic process GO:0019320 104 67 1,000 3,601E-03 0,10313958 ! negative regulation of kinase activity GO:0033673 131 68 1,000 3,707E-03 0,10492697 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 3,707E-03 0,10370689 ! negative regulation of cell size GO:0045792 134 69 1,000 3,814E-03 0,10548666 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 3,814E-03 0,10428795 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 4,145E-03 0,1120648 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 4,145E-03 0,11081964 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 4,145E-03 0,10960184 ! negative regulation of transferase activity GO:0051348 140 72 1,000 4,145E-03 0,10841052 ! eye development GO:0001654 143 74 1,000 4,373E-03 0,11313924 ! monosaccharide catabolic process GO:0046365 115 76 1,000 4,607E-03 0,11791307 ! positive regulation of ligase activity GO:0051351 124 77 1,000 4,726E-03 0,11968297 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 4,726E-03 0,11843627 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 4,968E-03 0,12321828 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 4,968E-03 0,12196095 ! response to metal ion GO:0010038 140 80 1,000 5,091E-03 0,12372112 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 5,215E-03 0,1254798 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of growth GO:0045926 155 84 1,000 5,597E-03 0,13333541 ! regulation of ligase activity GO:0051340 142 84 1,000 5,597E-03 0,1320282 ! positive regulation of cell activation GO:0050867 145 85 1,000 5,727E-03 0,133785 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 5,859E-03 0,13553999 ! oxidative phosphorylation GO:0006119 133 86 1,000 5,859E-03 0,13424913 ! mitochondrion organization GO:0007005 148 86 1,000 5,859E-03 0,13298263 ! cellular respiration GO:0045333 135 88 1,000 6,126E-03 0,13774493 ! positive regulation of protein modification process GO:0031401 136 88 1,000 6,126E-03 0,13646951 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 6,624E-03 0,14620511 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 6,624E-03 0,14487597 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 6,624E-03 0,14357079 ! positive regulation of helicase activity GO:0051096 11 5 0,000 6,624E-03 0,1422889 ! neuron fate determination GO:0048664 7 5 0,000 6,624E-03 0,14102971 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,624E-03 0,13979261 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 6,624E-03 0,13857702 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 6,624E-03 0,13738239 ! polyol transport GO:0015791 12 5 0,000 6,624E-03 0,13620818 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 6,624E-03 0,13505387 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 6,624E-03 0,13391897 ! response to superoxide GO:0000303 10 5 0,000 6,624E-03 0,13280298 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,624E-03 0,13170543 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 6,624E-03 0,13062588 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 6,624E-03 0,12956388 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 6,624E-03 0,12851901 ! female meiosis GO:0007143 7 5 0,000 6,624E-03 0,12749086 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 6,624E-03 0,12647903 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 6,624E-03 0,12548313 ! cobalt ion transport GO:0006824 11 5 0,000 6,624E-03 0,12450279 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 6,624E-03 0,12353765 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 6,624E-03 0,12258736 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 6,624E-03 0,12165158 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 6,624E-03 0,12072998 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 6,624E-03 0,11982223 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 6,624E-03 0,11892804 ! embryonic camera-type eye development GO:0031076 10 5 0,000 6,624E-03 0,11804709 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 6,624E-03 0,1171791 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 6,624E-03 0,11632378 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 6,624E-03 0,11548085 ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,624E-03 0,11465005 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 6,624E-03 0,11383112 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 6,624E-03 0,11302381 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 6,624E-03 0,11222787 ! negative chemotaxis GO:0050919 14 5 0,000 6,624E-03 0,11144306 ! positive regulation of histone modification GO:0031058 5 5 0,000 6,624E-03 0,11066915 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,624E-03 0,10990591 ! sensory perception of bitter taste GO:0050913 7 5 0,000 6,624E-03 0,10915313 ! behavioral response to pain GO:0048266 9 5 0,000 6,624E-03 0,10841059 ! clathrin coat assembly GO:0048268 14 5 0,000 6,624E-03 0,10767809 ! Notch receptor processing GO:0007220 8 5 0,000 6,624E-03 0,10695542 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,624E-03 0,10624238 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 6,624E-03 0,10553879 ! micturition GO:0060073 9 5 0,000 6,624E-03 0,10484446 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 6,624E-03 0,1041592 ! copulation GO:0007620 9 5 0,000 6,624E-03 0,10348284 ! glial cell fate commitment GO:0021781 13 5 0,000 6,624E-03 0,10281521 ! protein maturation by protein folding GO:0022417 13 5 0,000 6,624E-03 0,10215614 ! spermidine metabolic process GO:0008216 7 5 0,000 6,624E-03 0,10150546 ! regulation of potassium ion transport GO:0043266 10 5 0,000 6,624E-03 0,10086302 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 6,624E-03 0,10022866 ! apoptotic cell clearance GO:0043277 20 5 0,000 6,624E-03 0,09960223 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 6,624E-03 0,09898359 ! lipoprotein particle clearance GO:0034381 10 5 0,000 6,624E-03 0,09837258 ! grooming behavior GO:0007625 6 5 0,000 6,624E-03 0,09776906 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 6,624E-03 0,09717291 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 6,624E-03 0,09658398 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,624E-03 0,09600215 ! response to protozoan GO:0001562 10 5 0,000 6,624E-03 0,09542729 ! positive regulation of glycolysis GO:0045821 14 5 0,000 6,624E-03 0,09485927 ! lymph vessel development GO:0001945 10 5 0,000 6,624E-03 0,09429797 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 6,624E-03 0,09374328 ! endochondral ossification GO:0001958 16 5 0,000 6,624E-03 0,09319507 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 6,624E-03 0,09265324 ! parathyroid gland development GO:0060017 13 5 0,000 6,624E-03 0,09211767 ! anagen GO:0042640 6 5 0,000 6,624E-03 0,09158826 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 6,624E-03 0,0910649 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 6,624E-03 0,09054748 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 6,624E-03 0,09003592 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 6,624E-03 0,0895301 ! dorsal spinal cord development GO:0021516 7 5 0,000 6,624E-03 0,08902993 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 6,624E-03 0,08853532 ! sphingoid catabolic process GO:0046521 6 5 0,000 6,624E-03 0,08804617 ! skeletal myofibril assembly GO:0014866 10 5 0,000 6,624E-03 0,0875624 ! smooth muscle tissue development GO:0048745 28 5 0,000 6,624E-03 0,08708392 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,624E-03 0,08661064 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 6,624E-03 0,08614247 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 6,624E-03 0,08567934 ! cardiac muscle fiber development GO:0048739 10 5 0,000 6,624E-03 0,08522116 ! transepithelial chloride transport GO:0030321 9 5 0,000 6,624E-03 0,08476786 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,624E-03 0,08431935 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 6,624E-03 0,08387556 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 6,624E-03 0,08343643 ! neutrophil mediated immunity GO:0002446 7 5 0,000 6,624E-03 0,08300186 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 6,624E-03 0,0825718 ! histidine catabolic process GO:0006548 6 5 0,000 6,624E-03 0,08214617 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 6,624E-03 0,08172491 ! microvillus organization GO:0032528 7 5 0,000 6,624E-03 0,08130795 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 6,624E-03 0,08089521 ! L-serine biosynthetic process GO:0006564 6 5 0,000 6,624E-03 0,08048665 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 6,624E-03 0,0800822 ! tryptophan metabolic process GO:0006568 9 5 0,000 6,624E-03 0,07968179 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 6,624E-03 0,07928536 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 6,624E-03 0,07889286 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 6,624E-03 0,07850422 ! polyol biosynthetic process GO:0046173 5 5 0,000 6,624E-03 0,0781194 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 6,624E-03 0,07773833 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 6,624E-03 0,07736096 ! muscle cell migration GO:0014812 8 5 0,000 6,624E-03 0,07698723 ! mitochondrial fission GO:0000266 8 5 0,000 6,624E-03 0,0766171 ! sister chromatid cohesion GO:0007062 12 5 0,000 6,624E-03 0,07625051 ! mRNA transcription GO:0009299 9 5 0,000 6,624E-03 0,07588742 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 6,624E-03 0,07552776 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 6,624E-03 0,0751715 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 6,624E-03 0,07481858 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 6,624E-03 0,07446896 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 6,624E-03 0,07412259 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 6,624E-03 0,07377943 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 6,624E-03 0,07343943 ! response to food GO:0032094 6 5 0,000 6,624E-03 0,07310256 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 6,624E-03 0,07276875 ! positive regulation of transporter activity GO:0032411 8 5 0,000 6,624E-03 0,07243799 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 6,624E-03 0,07211021 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,624E-03 0,07178539 ! paraxial mesoderm development GO:0048339 14 5 0,000 6,624E-03 0,07146349 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 6,624E-03 0,07114445 ! forebrain neuron development GO:0021884 13 5 0,000 6,624E-03 0,07082825 ! lipoprotein catabolic process GO:0042159 11 5 0,000 6,624E-03 0,07051485 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 6,624E-03 0,07020422 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 6,624E-03 0,0698963 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,624E-03 0,06959108 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 6,624E-03 0,06928851 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 6,624E-03 0,06898856 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,624E-03 0,06869119 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 6,624E-03 0,06839638 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 6,624E-03 0,06810409 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 6,624E-03 0,06781429 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 6,624E-03 0,06752694 ! basic amino acid transport GO:0015802 11 5 0,000 6,624E-03 0,06724201 ! cellular glucose homeostasis GO:0001678 5 5 0,000 6,624E-03 0,06695948 ! early endosome to late endosome transport GO:0045022 12 5 0,000 6,624E-03 0,06667932 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,624E-03 0,06640149 ! depyrimidination GO:0045008 10 5 0,000 6,624E-03 0,06612596 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,624E-03 0,06585272 ! regulation of centrosome cycle GO:0046605 7 5 0,000 6,624E-03 0,06558172 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 6,624E-03 0,06531294 ! zinc ion homeostasis GO:0055069 8 5 0,000 6,624E-03 0,06504636 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 6,624E-03 0,06478194 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 6,624E-03 0,06451966 ! forebrain morphogenesis GO:0048853 13 5 0,000 6,624E-03 0,0642595 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 6,624E-03 0,06400143 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 6,624E-03 0,06374543 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 6,624E-03 0,06349146 ! peptidyl-arginine modification GO:0018195 9 5 0,000 6,624E-03 0,06323951 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,624E-03 0,06298955 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,624E-03 0,06274156 ! response to arsenic GO:0046685 10 5 0,000 6,624E-03 0,06249552 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 6,624E-03 0,0622514 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 6,624E-03 0,06200917 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 6,624E-03 0,06176883 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 6,624E-03 0,06153034 ! response to cadmium ion GO:0046686 7 5 0,000 6,624E-03 0,06129368 ! bile acid biosynthetic process GO:0006699 6 5 0,000 6,624E-03 0,06105884 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 6,624E-03 0,06082579 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 6,624E-03 0,06059451 ! decidualization GO:0046697 11 5 0,000 6,624E-03 0,06036499 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 6,624E-03 0,0601372 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 6,624E-03 0,05991112 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 6,624E-03 0,05968673 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 6,624E-03 0,05946402 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 6,624E-03 0,05924296 ! base conversion or substitution editing GO:0016553 5 5 0,000 6,624E-03 0,05902355 ! neural tube patterning GO:0021532 7 5 0,000 6,624E-03 0,05880575 ! embryonic cleavage GO:0040016 6 5 0,000 6,624E-03 0,05858955 ! peroxisome fission GO:0016559 5 5 0,000 6,624E-03 0,05837493 ! histone demethylation GO:0016577 10 5 0,000 6,624E-03 0,05816189 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 6,624E-03 0,05795039 ! mitotic recombination GO:0006312 9 5 0,000 6,624E-03 0,05774042 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 6,624E-03 0,05753198 ! metaphase plate congression GO:0051310 7 5 0,000 6,624E-03 0,05732503 ! regulation of sterol transport GO:0032371 7 5 0,000 6,624E-03 0,05711956 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 6,624E-03 0,05691556 ! enteric nervous system development GO:0048484 8 5 0,000 6,624E-03 0,05671302 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 6,624E-03 0,05651191 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 6,624E-03 0,05631222 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 6,624E-03 0,05611393 ! muscle cell proliferation GO:0033002 11 5 0,000 6,624E-03 0,05591704 ! skeletal muscle regeneration GO:0043403 8 5 0,000 6,624E-03 0,05572153 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 6,624E-03 0,05552738 ! plasminogen activation GO:0031639 5 5 0,000 6,624E-03 0,05533457 ! B cell homeostasis GO:0001782 13 5 0,000 6,624E-03 0,0551431 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 6,624E-03 0,05495296 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 6,624E-03 0,05476411 ! metaphase GO:0051323 8 5 0,000 6,624E-03 0,05457657 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 6,624E-03 0,0543903 ! cellular response to nutrient GO:0031670 8 5 0,000 6,624E-03 0,0542053 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 6,624E-03 0,05402155 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 6,624E-03 0,05383904 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 6,624E-03 0,05365777 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 6,624E-03 0,05347771 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 6,624E-03 0,05329885 ! response to redox state GO:0051775 5 5 0,000 6,624E-03 0,05312119 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 6,624E-03 0,05294471 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 6,624E-03 0,05276939 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,624E-03 0,05259524 ! regulation of telomerase activity GO:0051972 6 5 0,000 6,624E-03 0,05242223 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,624E-03 0,05225035 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 6,624E-03 0,0520796 ! porphyrin catabolic process GO:0006787 12 5 0,000 6,624E-03 0,05190996 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 6,624E-03 0,05174142 ! striatum development GO:0021756 9 5 0,000 6,624E-03 0,05157397 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 6,624E-03 0,0514076 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 6,624E-03 0,05124231 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 6,624E-03 0,05107807 ! glial cell migration GO:0008347 11 5 0,000 6,624E-03 0,05091488 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,624E-03 0,05075273 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 6,624E-03 0,05059161 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 6,624E-03 0,05043151 ! somatic stem cell maintenance GO:0035019 15 5 0,000 6,624E-03 0,05027242 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 6,624E-03 0,05011433 ! negative regulation of lipase activity GO:0060192 8 5 0,000 6,624E-03 0,04995723 ! neuroprotection GO:0043526 6 5 0,000 6,624E-03 0,04980112 ! neural plate development GO:0001840 8 5 0,000 6,624E-03 0,04964597 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 6,624E-03 0,04949179 ! regulation of sensory perception GO:0051931 7 5 0,000 6,624E-03 0,04933857 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 6,624E-03 0,04918629 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 6,624E-03 0,04903495 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 6,624E-03 0,04888453 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 6,624E-03 0,04873504 ! sequestering of calcium ion GO:0051208 7 5 0,000 6,624E-03 0,04858645 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 6,624E-03 0,04843878 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 6,624E-03 0,04829199 ! spindle assembly GO:0051225 6 5 0,000 6,624E-03 0,04814609 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 6,624E-03 0,04800108 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 6,624E-03 0,04785693 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 6,624E-03 0,04771364 ! drug metabolic process GO:0017144 6 5 0,000 6,624E-03 0,04757122 ! stem cell division GO:0017145 11 5 0,000 6,624E-03 0,04742963 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 6,624E-03 0,04728889 ! organ regeneration GO:0031100 7 5 0,000 6,624E-03 0,04714899 ! carnitine metabolic process GO:0009437 7 5 0,000 6,624E-03 0,0470099 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 6,624E-03 0,04687164 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 6,624E-03 0,04673419 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 6,817E-03 0,04796095 GO:0010498|proteasomal protein catabolic process, ! response to virus GO:0009615 160 98 1,000 7,543E-03 0,05290945 ! Golgi vesicle transport GO:0048193 207 99 1,000 7,692E-03 0,05379845 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 7,943E-03 0,05539494 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 7,943E-03 0,05523484 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 7,943E-03 0,05507567 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 7,943E-03 0,0549174 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 7,943E-03 0,05476005 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 7,943E-03 0,05460359 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 7,943E-03 0,05444802 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 7,943E-03 0,05429334 ! sleep GO:0030431 13 6 0,000 7,943E-03 0,05413953 ! response to oxygen radical GO:0000305 11 6 0,000 7,943E-03 0,0539866 ! positive regulation of axon extension GO:0045773 11 6 0,000 7,943E-03 0,05383452 ! myoblast cell fate commitment GO:0048625 16 6 0,000 7,943E-03 0,0536833 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 7,943E-03 0,05353293 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 7,943E-03 0,0533834 ! regulation of interferon-beta production GO:0032648 8 6 0,000 7,943E-03 0,0532347 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 7,943E-03 0,05308682 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 7,943E-03 0,05293977 ! forebrain regionalization GO:0021871 8 6 0,000 7,943E-03 0,05279352 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 7,943E-03 0,05264809 ! male meiosis GO:0007140 7 6 0,000 7,943E-03 0,05250345 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 7,943E-03 0,0523596 ! response to zinc ion GO:0010043 9 6 0,000 7,943E-03 0,05221655 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 7,943E-03 0,05207427 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 7,943E-03 0,05193276 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 7,943E-03 0,05179202 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 7,943E-03 0,05165204 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 7,943E-03 0,05151282 ! malate metabolic process GO:0006108 11 6 0,000 7,943E-03 0,05137434 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 7,943E-03 0,05123661 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 7,943E-03 0,05109961 ! protein refolding GO:0042026 15 6 0,000 7,943E-03 0,05096335 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 7,943E-03 0,05082781 ! opsonization GO:0008228 8 6 0,000 7,943E-03 0,05069299 ! mating behavior GO:0007617 7 6 0,000 7,943E-03 0,05055888 ! neuron remodeling GO:0016322 15 6 0,000 7,943E-03 0,05042548 ! erythrocyte maturation GO:0043249 7 6 0,000 7,943E-03 0,05029278 ! embryonic hemopoiesis GO:0035162 14 6 0,000 7,943E-03 0,05016078 ! equilibrioception GO:0050957 14 6 0,000 7,943E-03 0,05002947 ! protein amino acid dealkylation GO:0008214 12 6 0,000 7,943E-03 0,04989884 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 7,943E-03 0,0497689 ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 7,943E-03 0,04963963 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 7,943E-03 0,04951103 ! response to interferon-gamma GO:0034341 15 6 0,000 7,943E-03 0,04938309 ! toxin metabolic process GO:0009404 11 6 0,000 7,943E-03 0,04925581 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 7,943E-03 0,04912919 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 7,943E-03 0,04900322 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 7,943E-03 0,04887789 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 7,943E-03 0,0487532 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 7,943E-03 0,04862915 ! cGMP-mediated signaling GO:0019934 13 6 0,000 7,943E-03 0,04850573 ! activation of MAPKKK activity GO:0000185 12 6 0,000 7,943E-03 0,04838293 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 7,943E-03 0,04826075 ! thymic T cell selection GO:0045061 12 6 0,000 7,943E-03 0,04813918 ! protein lipoylation GO:0009249 10 6 0,000 7,943E-03 0,04801823 ! cysteine metabolic process GO:0006534 10 6 0,000 7,943E-03 0,04789788 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 7,943E-03 0,04777814 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 7,943E-03 0,04765899 ! glutamate catabolic process GO:0006538 10 6 0,000 7,943E-03 0,04754044 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 7,943E-03 0,04742247 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 7,943E-03 0,04730509 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 7,943E-03 0,04718829 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 7,943E-03 0,04707206 ! hyperosmotic response GO:0006972 9 6 0,000 7,943E-03 0,0469564 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 7,943E-03 0,04684131 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 7,943E-03 0,04672679 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 7,943E-03 0,04661282 ! urea metabolic process GO:0019627 7 6 0,000 7,943E-03 0,04649941 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 7,943E-03 0,04638654 ! neutrophil activation GO:0042119 8 6 0,000 7,943E-03 0,04627423 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 7,943E-03 0,04616245 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 7,943E-03 0,04605122 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 7,943E-03 0,04594052 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 7,943E-03 0,04583035 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 7,943E-03 0,04572071 ! neuron apoptosis GO:0051402 9 6 0,000 7,943E-03 0,04561159 ! nucleoside salvage GO:0043174 9 6 0,000 7,943E-03 0,04550299 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 7,943E-03 0,04539491 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 7,943E-03 0,04528734 ! T cell mediated immunity GO:0002456 16 6 0,000 7,943E-03 0,04518027 ! negative regulation of platelet activation GO:0010544 9 6 0,000 7,943E-03 0,04507372 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 7,943E-03 0,04496766 ! carnitine transport GO:0015879 10 6 0,000 7,943E-03 0,0448621 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 7,943E-03 0,04475704 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,943E-03 0,04465247 ! positive regulation of exocytosis GO:0045921 8 6 0,000 7,943E-03 0,04454838 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 7,943E-03 0,04444478 ! 5S class rRNA transcription GO:0042791 11 6 0,000 7,943E-03 0,04434166 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 7,943E-03 0,04423902 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 7,943E-03 0,04413685 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 7,943E-03 0,04403515 ! sodium ion homeostasis GO:0055078 11 6 0,000 7,943E-03 0,04393392 ! establishment of spindle localization GO:0051293 12 6 0,000 7,943E-03 0,04383316 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 7,943E-03 0,04373285 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 7,943E-03 0,043633 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 7,943E-03 0,04353361 ! neural nucleus development GO:0048857 14 6 0,000 7,943E-03 0,04343467 ! response to UV-C GO:0010225 11 6 0,000 7,943E-03 0,04333618 ! astrocyte development GO:0014002 15 6 0,000 7,943E-03 0,04323814 ! protein targeting to lysosome GO:0006622 10 6 0,000 7,943E-03 0,04314053 ! purine base biosynthetic process GO:0009113 17 6 0,000 7,943E-03 0,04304337 ! interaction with symbiont GO:0051702 13 6 0,000 7,943E-03 0,04294664 ! regulation of dendrite development GO:0050773 16 6 0,000 7,943E-03 0,04285035 ! skeletal muscle contraction GO:0003009 6 6 0,000 7,943E-03 0,04275449 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 7,943E-03 0,04265905 ! response to copper ion GO:0046688 10 6 0,000 7,943E-03 0,04256404 ! response to exogenous dsRNA GO:0043330 10 6 0,000 7,943E-03 0,04246946 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 7,943E-03 0,04237529 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,943E-03 0,04228154 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 7,943E-03 0,0421882 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 7,943E-03 0,04209528 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 7,943E-03 0,04200276 ! regulation of dopamine secretion GO:0014059 14 6 0,000 7,943E-03 0,04191065 ! nucleoside catabolic process GO:0009164 7 6 0,000 7,943E-03 0,04181894 ! hair follicle maturation GO:0048820 7 6 0,000 7,943E-03 0,04172763 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 7,943E-03 0,04163672 ! Schwann cell development GO:0014044 15 6 0,000 7,943E-03 0,04154621 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 7,943E-03 0,04145609 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 7,943E-03 0,04136635 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 7,943E-03 0,04127701 ! subpallium development GO:0021544 10 6 0,000 7,943E-03 0,04118805 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 7,943E-03 0,04109947 ! histone ubiquitination GO:0016574 8 6 0,000 7,943E-03 0,04101128 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 7,943E-03 0,04092346 ! maintenance of organ identity GO:0048496 9 6 0,000 7,943E-03 0,04083602 ! G2 phase GO:0051319 16 6 0,000 7,943E-03 0,04074895 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 7,943E-03 0,04066225 ! establishment of planar polarity GO:0001736 7 6 0,000 7,943E-03 0,04057591 ! regulation of mast cell activation GO:0033003 12 6 0,000 7,943E-03 0,04048995 ! membrane to membrane docking GO:0022614 14 6 0,000 7,943E-03 0,04040435 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 7,943E-03 0,04031911 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 7,943E-03 0,04023422 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 7,943E-03 0,0401497 ! receptor internalization GO:0031623 10 6 0,000 7,943E-03 0,04006553 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 7,943E-03 0,03998171 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 7,943E-03 0,03989824 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 7,943E-03 0,03981512 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 7,943E-03 0,03973234 ! protein deubiquitination GO:0016579 14 6 0,000 7,943E-03 0,03964991 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 7,943E-03 0,03956782 ! protein destabilization GO:0031648 9 6 0,000 7,943E-03 0,03948607 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 7,943E-03 0,03940465 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 7,943E-03 0,03932357 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 7,943E-03 0,03924283 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 7,943E-03 0,03916241 ! progesterone metabolic process GO:0042448 10 6 0,000 7,943E-03 0,03908232 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 7,943E-03 0,03900256 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 7,943E-03 0,03892313 ! negative regulation of axon extension GO:0030517 21 6 0,000 7,943E-03 0,03884402 ! removal of superoxide radicals GO:0019430 11 6 0,000 7,943E-03 0,03876522 ! triglyceride catabolic process GO:0019433 10 6 0,000 7,943E-03 0,03868675 ! determination of adult lifespan GO:0008340 15 6 0,000 7,943E-03 0,0386086 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 7,943E-03 0,03853076 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 7,943E-03 0,03845323 ! cerebellar cortex formation GO:0021697 8 6 0,000 7,943E-03 0,03837602 ! catecholamine transport GO:0051937 9 6 0,000 7,943E-03 0,03829911 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 7,943E-03 0,03822251 ! sensory cilium assembly GO:0035058 10 6 0,000 7,943E-03 0,03814622 ! organ or tissue specific immune response GO:0002251 7 6 0,000 7,943E-03 0,03807023 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 7,943E-03 0,03799454 ! maternal placenta development GO:0001893 12 6 0,000 7,943E-03 0,03791916 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 7,943E-03 0,03784407 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 7,943E-03 0,03776928 ! negative regulation of B cell activation GO:0050869 13 6 0,000 7,943E-03 0,03769478 ! protein amino acid prenylation GO:0018346 16 6 0,000 7,943E-03 0,03762058 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 7,943E-03 0,03754667 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 7,943E-03 0,03747305 ! positive regulation of coagulation GO:0050820 12 6 0,000 7,943E-03 0,03739972 ! tRNA transcription GO:0009304 14 7 0,000 9,261E-03 0,04351961 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 9,261E-03 0,04343478 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 9,261E-03 0,04335028 ! behavioral response to cocaine GO:0048148 14 7 0,000 9,261E-03 0,0432661 ! regulation of helicase activity GO:0051095 15 7 0,000 9,261E-03 0,04318225 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 9,261E-03 0,04309873 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 9,261E-03 0,04301553 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 9,261E-03 0,04293264 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 9,261E-03 0,04285008 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 9,261E-03 0,04276784 ! prostate gland development GO:0030850 13 7 0,000 9,261E-03 0,0426859 ! nucleotide-sugar transport GO:0015780 12 7 0,000 9,261E-03 0,04260429 ! synaptonemal complex assembly GO:0007130 10 7 0,000 9,261E-03 0,04252298 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 9,261E-03 0,04244199 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 9,261E-03 0,0423613 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 9,261E-03 0,04228092 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 9,261E-03 0,04220084 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 9,261E-03 0,04212106 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 9,261E-03 0,04204159 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 9,261E-03 0,04196241 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 9,261E-03 0,04188354 ! SMAD protein complex assembly GO:0007183 12 7 0,000 9,261E-03 0,04180496 ! glycolipid transport GO:0046836 10 7 0,000 9,261E-03 0,04172667 ! protein amino acid sulfation GO:0006477 10 7 0,000 9,261E-03 0,04164868 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 9,261E-03 0,04157097 ! neuron adhesion GO:0007158 12 7 0,000 9,261E-03 0,04149356 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 9,261E-03 0,04141644 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 9,261E-03 0,0413396 ! actin-myosin filament sliding GO:0033275 11 7 0,000 9,261E-03 0,04126304 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 9,261E-03 0,04118677 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 9,261E-03 0,04111078 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 9,261E-03 0,04103507 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 9,261E-03 0,04095964 ! mRNA stabilization GO:0048255 18 7 0,000 9,261E-03 0,04088448 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 9,261E-03 0,0408096 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 9,261E-03 0,04073499 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 9,261E-03 0,04066066 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 9,261E-03 0,0405866 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 9,261E-03 0,0405128 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 9,261E-03 0,04043928 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 9,261E-03 0,04036602 ! lipoprotein transport GO:0042953 14 7 0,000 9,261E-03 0,04029302 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 9,261E-03 0,04022029 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 9,261E-03 0,04014782 ! rhythmic behavior GO:0007622 15 7 0,000 9,261E-03 0,04007562 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 9,261E-03 0,04000367 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 9,261E-03 0,03993198 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 9,261E-03 0,03986054 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 9,261E-03 0,03978936 ! regulation of odontogenesis GO:0042481 13 7 0,000 9,261E-03 0,03971844 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 9,261E-03 0,03964776 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 9,261E-03 0,03957734 ! mechanosensory behavior GO:0007638 14 7 0,000 9,261E-03 0,03950717 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 9,261E-03 0,03943724 ! positive regulation of isotype switching GO:0045830 15 7 0,000 9,261E-03 0,03936757 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 9,261E-03 0,03929813 ! protein-cofactor linkage GO:0018065 13 7 0,000 9,261E-03 0,03922895 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 9,261E-03 0,03916 ! spinal cord patterning GO:0021511 13 7 0,000 9,261E-03 0,0390913 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 9,261E-03 0,03902284 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 9,261E-03 0,03895462 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 9,261E-03 0,03888664 ! adrenal gland development GO:0030325 17 7 0,000 9,261E-03 0,03881889 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 9,261E-03 0,03875138 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 9,261E-03 0,0386841 ! ovulation GO:0030728 9 7 0,000 9,261E-03 0,03861706 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 9,261E-03 0,03855025 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 9,261E-03 0,03848367 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 9,261E-03 0,03841731 ! microtubule nucleation GO:0007020 20 7 0,000 9,261E-03 0,03835119 ! proline biosynthetic process GO:0006561 10 7 0,000 9,261E-03 0,0382853 ! thyroid hormone generation GO:0006590 13 7 0,000 9,261E-03 0,03821963 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 9,261E-03 0,03815418 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 9,261E-03 0,03808896 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 9,261E-03 0,03802396 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 9,261E-03 0,03795919 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 9,261E-03 0,03789463 ! galactose metabolic process GO:0006012 13 7 0,000 9,261E-03 0,03783029 ! vesicle fusion GO:0006906 17 7 0,000 9,261E-03 0,03776617 ! response to dietary excess GO:0002021 8 7 0,000 9,261E-03 0,03770227 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 9,261E-03 0,03763858 ! intracellular pH reduction GO:0051452 11 7 0,000 9,261E-03 0,03757511 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 9,261E-03 0,03751186 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 9,261E-03 0,03744881 ! organ growth GO:0035265 15 7 0,000 9,261E-03 0,03738598 ! purine salvage GO:0043101 10 7 0,000 9,261E-03 0,03732335 ! nucleoside transport GO:0015858 8 7 0,000 9,261E-03 0,03726094 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 9,261E-03 0,03719873 ! parturition GO:0007567 14 7 0,000 9,261E-03 0,03713674 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 9,261E-03 0,03707495 ! rRNA modification GO:0000154 14 7 0,000 9,261E-03 0,03701336 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 9,261E-03 0,03695198 ! spindle checkpoint GO:0031577 15 7 0,000 9,261E-03 0,0368908 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 9,261E-03 0,03682982 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 9,261E-03 0,03676905 ! macrophage differentiation GO:0030225 11 7 0,000 9,261E-03 0,03670847 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 9,261E-03 0,0366481 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 9,261E-03 0,03658792 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 9,261E-03 0,03652794 ! hyaluronan metabolic process GO:0030212 8 7 0,000 9,261E-03 0,03646815 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 9,261E-03 0,03640857 ! anterograde axon cargo transport GO:0008089 18 7 0,000 9,261E-03 0,03634917 ! fibrinolysis GO:0042730 10 7 0,000 9,261E-03 0,03628997 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 9,261E-03 0,03623096 ! eating behavior GO:0042755 7 7 0,000 9,261E-03 0,03617215 ! B cell lineage commitment GO:0002326 21 7 0,000 9,261E-03 0,03611352 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 9,261E-03 0,03605508 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 9,261E-03 0,03599684 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 9,261E-03 0,03593878 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 9,261E-03 0,03588091 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 9,261E-03 0,03582322 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 9,261E-03 0,03576572 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 9,261E-03 0,0357084 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 9,261E-03 0,03565127 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 9,261E-03 0,03559432 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 9,261E-03 0,03553755 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 9,261E-03 0,03548096 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 9,261E-03 0,03542455 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 9,261E-03 0,03536832 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 9,261E-03 0,03531227 ! regulation of meiosis GO:0040020 12 7 0,000 9,261E-03 0,0352564 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 9,261E-03 0,0352007 ! T cell lineage commitment GO:0002360 16 7 0,000 9,261E-03 0,03514518 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 9,261E-03 0,03508983 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 9,261E-03 0,03503466 ! oxygen homeostasis GO:0032364 12 7 0,000 9,261E-03 0,03497966 ! transcription termination GO:0006353 13 7 0,000 9,261E-03 0,03492483 ! response to tumor cell GO:0002347 13 7 0,000 9,261E-03 0,03487018 ! regulation of respiratory burst GO:0060263 11 7 0,000 9,261E-03 0,03481569 ! coenzyme A metabolic process GO:0015936 12 7 0,000 9,261E-03 0,03476138 ! anaphase GO:0051322 17 7 0,000 9,261E-03 0,03470723 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 9,261E-03 0,03465325 ! axonal fasciculation GO:0007413 18 7 0,000 9,261E-03 0,03459944 ! negative regulation of nuclear division GO:0051784 14 7 0,000 9,261E-03 0,0345458 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 9,261E-03 0,03449233 ! peptidyl-threonine modification GO:0018210 25 7 0,000 9,261E-03 0,03443901 ! diuresis GO:0030146 12 7 0,000 9,261E-03 0,03438587 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 9,261E-03 0,03433288 ! thiamin metabolic process GO:0006772 7 7 0,000 9,261E-03 0,03428006 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 9,261E-03 0,03422741 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 9,261E-03 0,03417491 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 9,261E-03 0,03412258 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 9,261E-03 0,0340704 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 9,261E-03 0,03401839 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 9,261E-03 0,03396653 ! melanin biosynthetic process GO:0042438 8 7 0,000 9,261E-03 0,03391483 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 9,261E-03 0,03386329 ! dopamine biosynthetic process GO:0042416 18 7 0,000 9,261E-03 0,0338119 ! glycolipid catabolic process GO:0019377 15 7 0,000 9,261E-03 0,03376067 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 9,261E-03 0,03370959 ! lymph node development GO:0048535 10 7 0,000 9,261E-03 0,03365867 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 9,261E-03 0,03360791 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 9,261E-03 0,03355729 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 9,261E-03 0,03350683 ! endosome to lysosome transport GO:0008333 11 7 0,000 9,261E-03 0,03345652 ! protein modification by small protein removal GO:0070646 16 7 0,000 9,261E-03 0,03340636 ! adult feeding behavior GO:0008343 9 7 0,000 9,261E-03 0,03335635 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 9,261E-03 0,03330649 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 9,261E-03 0,03325678 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 9,261E-03 0,03320722 ! muscle adaptation GO:0043500 14 7 0,000 9,261E-03 0,0331578 ! embryonic heart tube development GO:0035050 10 7 0,000 9,261E-03 0,03310853 ! retina homeostasis GO:0001895 12 7 0,000 9,261E-03 0,03305941 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 9,261E-03 0,03301043 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 9,261E-03 0,0329616 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 9,261E-03 0,03291291 ! protein prenylation GO:0018342 18 7 0,000 9,261E-03 0,03286437 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 9,261E-03 0,03281597 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 9,261E-03 0,03276771 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 9,261E-03 0,03271959 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01057719 0,03731484 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01057719 0,03726021 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01057719 0,03720573 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01057719 0,03715142 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01057719 0,03709726 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01057719 0,03704326 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01057719 0,03698942 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01057719 0,03693574 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01057719 0,03688221 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01057719 0,03682883 ! meiotic prophase I GO:0007128 13 8 0,000 0,01057719 0,03677561 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01057719 0,03672254 ! oligopeptide transport GO:0006857 15 8 0,000 0,01057719 0,03666963 ! UTP metabolic process GO:0046051 8 8 0,000 0,01057719 0,03661687 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01057719 0,03656426 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01057719 0,0365118 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01057719 0,03645949 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01057719 0,03640733 ! succinate metabolic process GO:0006105 14 8 0,000 0,01057719 0,03635532 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01057719 0,03630345 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01057719 0,03625174 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01057719 0,03620017 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01057719 0,03614875 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01057719 0,03609748 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01057719 0,03604635 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01057719 0,03599536 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01057719 0,03594452 ! reflex GO:0060004 16 8 0,000 0,01057719 0,03589382 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01057719 0,03584327 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01057719 0,03579286 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01057719 0,03574259 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01057719 0,03569246 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01057719 0,03564247 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01057719 0,03559262 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01057719 0,03554291 ! pigment granule organization GO:0048753 16 8 0,000 0,01057719 0,03549334 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01057719 0,0354439 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01057719 0,03539461 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01057719 0,03534545 ! histidine metabolic process GO:0006547 16 8 0,000 0,01057719 0,03529642 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01057719 0,03524754 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01057719 0,03519879 ! glycine catabolic process GO:0006546 13 8 0,000 0,01057719 0,03515017 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01057719 0,03510169 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01057719 0,03505334 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01057719 0,03500512 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01057719 0,03495704 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01057719 0,03490908 ! melanin metabolic process GO:0006582 15 8 0,000 0,01057719 0,03486126 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01057719 0,03481357 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01057719 0,03476601 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01057719 0,03471858 ! macrophage activation GO:0042116 12 8 0,000 0,01057719 0,03467128 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01057719 0,03462411 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01057719 0,03457707 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01057719 0,03453015 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01057719 0,03448336 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01057719 0,0344367 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01057719 0,03439016 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01057719 0,03434375 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01057719 0,03429747 ! osteoblast development GO:0002076 16 8 0,000 0,01057719 0,03425131 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01057719 0,03420527 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01057719 0,03415936 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01057719 0,03411357 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01057719 0,0340679 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01057719 0,03402236 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01057719 0,03397693 ! response to UV-B GO:0010224 16 8 0,000 0,01057719 0,03393163 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01057719 0,03388645 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01057719 0,03384139 ! intermediate filament organization GO:0045109 12 8 0,000 0,01057719 0,03379644 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01057719 0,03375162 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01057719 0,03370692 ! cellular extravasation GO:0045123 12 8 0,000 0,01057719 0,03366233 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01057719 0,03361786 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01057719 0,03357351 ! response to antibiotic GO:0046677 11 8 0,000 0,01057719 0,03352928 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01057719 0,03348516 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01057719 0,03344116 ! DNA topological change GO:0006265 12 8 0,000 0,01057719 0,03339727 ! response to tropane GO:0014073 15 8 0,000 0,01057719 0,0333535 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01057719 0,03330985 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01057719 0,0332663 ! melanosome transport GO:0032402 13 8 0,000 0,01057719 0,03322287 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,01057719 0,03317956 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01057719 0,03313636 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01057719 0,03309327 ! mast cell activation GO:0045576 14 8 0,000 0,01057719 0,03305029 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01057719 0,03300742 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01057719 0,03296467 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01057719 0,03292202 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01057719 0,03287949 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01057719 0,03283706 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01057719 0,03279474 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01057719 0,03275254 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01057719 0,03271044 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01057719 0,03266845 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01057719 0,03262657 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01057719 0,03258479 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01057719 0,03254312 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01057719 0,03250156 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01057719 0,0324601 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01057719 0,03241875 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01057719 0,03237751 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01057719 0,03233637 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01057719 0,03229533 ! hormone catabolic process GO:0042447 17 8 0,000 0,01057719 0,0322544 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01057719 0,03221357 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01057719 0,03217285 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01057719 0,03213222 ! ATP catabolic process GO:0006200 11 8 0,000 0,01057719 0,0320917 ! blastocyst growth GO:0001832 19 8 0,000 0,01057719 0,03205129 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01057719 0,03201097 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01057719 0,03197076 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01057719 0,03193064 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01057719 0,03189063 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01057719 0,03185072 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01057719 0,0318109 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01057719 0,03177119 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01057719 0,03173157 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01057719 0,03169206 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01057719 0,03165264 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01057719 0,03161332 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01057719 0,0315741 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01057719 0,03153497 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01057719 0,03149594 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01057719 0,03145701 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01057719 0,03141817 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01057719 0,03137943 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01189165 0,03523559 ! axon extension GO:0048675 15 9 0,000 0,01189165 0,03519225 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01189165 0,03514902 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01189165 0,03510589 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01189165 0,03506287 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01189165 0,03501995 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01189165 0,03497714 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01189165 0,03493443 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01189165 0,03489183 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01189165 0,03484933 ! phosphate transport GO:0006817 19 9 0,000 0,01189165 0,03480693 ! reproductive behavior GO:0019098 19 9 0,000 0,01189165 0,03476464 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01189165 0,03472245 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01189165 0,03468036 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01189165 0,03463838 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01189165 0,03459649 ! GTP metabolic process GO:0046039 9 9 0,000 0,01189165 0,03455471 ! RNA methylation GO:0001510 15 9 0,000 0,01189165 0,03451303 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01189165 0,03447144 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01189165 0,03442996 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01189165 0,03438858 ! artery development GO:0060840 24 9 0,000 0,01189165 0,0343473 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01189165 0,03430611 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01189165 0,03426503 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01189165 0,03422404 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01189165 0,03418315 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01189165 0,03414236 ! chemosensory behavior GO:0007635 20 9 0,000 0,01189165 0,03410167 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01189165 0,03406107 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01189165 0,03402057 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01189165 0,03398017 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01189165 0,03393986 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01189165 0,03389964 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01189165 0,03385953 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01189165 0,0338195 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01189165 0,03377957 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01189165 0,03373974 ! protein targeting to ER GO:0045047 22 9 0,000 0,01189165 0,0337 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01189165 0,03366035 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01189165 0,0336208 ! T cell selection GO:0045058 23 9 0,000 0,01189165 0,03358134 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,01189165 0,03354197 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01189165 0,03350269 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01189165 0,03346351 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01189165 0,03342442 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01189165 0,03338541 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01189165 0,0333465 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01189165 0,03330768 ! mannose metabolic process GO:0006013 13 9 0,000 0,01189165 0,03326895 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01189165 0,03323031 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01189165 0,03319176 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01189165 0,0331533 ! receptor clustering GO:0043113 18 9 0,000 0,01189165 0,03311493 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01189165 0,03307665 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01189165 0,03303845 ! ruffle organization GO:0031529 15 9 0,000 0,01189165 0,03300035 ! retinol metabolic process GO:0042572 18 9 0,000 0,01189165 0,03296233 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01189165 0,0329244 ! behavioral fear response GO:0001662 22 9 0,000 0,01189165 0,03288655 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01189165 0,03284879 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01189165 0,03281112 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01189165 0,03277354 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01189165 0,03273604 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01189165 0,03269863 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01189165 0,0326613 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01189165 0,03262406 ! segment specification GO:0007379 13 9 0,000 0,01189165 0,0325869 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01189165 0,03254983 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01189165 0,03251284 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01189165 0,03247594 ! response to amine stimulus GO:0014075 13 9 0,000 0,01189165 0,03243911 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01189165 0,03240238 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01189165 0,03236572 ! erythrocyte development GO:0048821 15 9 0,000 0,01189165 0,03232915 ! gas homeostasis GO:0033483 16 9 0,000 0,01189165 0,03229266 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01189165 0,03225626 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01189165 0,03221993 ! renal water homeostasis GO:0003091 14 9 0,000 0,01189165 0,03218369 ! postreplication repair GO:0006301 22 9 0,000 0,01189165 0,03214753 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01189165 0,03211145 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01189165 0,03207545 ! icosanoid secretion GO:0032309 15 9 0,000 0,01189165 0,03203953 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01189165 0,03200369 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01189165 0,03196793 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01189165 0,03193225 ! regulation of cell division GO:0051302 15 9 0,000 0,01189165 0,03189665 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01189165 0,03186114 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01189165 0,03182569 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01189165 0,03179033 ! sterol catabolic process GO:0016127 11 9 0,000 0,01189165 0,03175505 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01189165 0,03171984 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01189165 0,03168472 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01189165 0,03164967 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01189165 0,0316147 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01189165 0,0315798 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01189165 0,03154498 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01189165 0,03151024 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01189165 0,03147558 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01189165 0,03144099 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01189165 0,03140648 ! purine base metabolic process GO:0006144 21 9 0,000 0,01189165 0,03137204 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01189165 0,03133768 ! pigment granule transport GO:0051904 17 9 0,000 0,01189165 0,03130339 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01189165 0,03126918 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01189165 0,03123504 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01189165 0,03120098 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01189165 0,03116699 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01189165 0,03113308 ! mitochondrion localization GO:0051646 15 9 0,000 0,01189165 0,03109924 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,0132044 0,03449488 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0132044 0,03445746 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,0132044 0,03442013 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0132044 0,03438288 ! synapsis GO:0007129 13 10 0,000 0,0132044 0,03434571 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,0132044 0,03430862 ! N-glycan processing GO:0006491 20 10 0,000 0,0132044 0,03427161 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,0132044 0,03423468 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,0132044 0,03419783 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,0132044 0,03416105 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,0132044 0,03412436 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,0132044 0,03408775 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,0132044 0,03405121 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,0132044 0,03401475 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,0132044 0,03397837 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,0132044 0,03394207 ! androgen metabolic process GO:0008209 17 10 0,000 0,0132044 0,03390585 ! phospholipid efflux GO:0033700 16 10 0,000 0,0132044 0,0338697 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0132044 0,03383363 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,0132044 0,03379764 ! lung alveolus development GO:0048286 26 10 0,000 0,0132044 0,03376172 ! pathogenesis GO:0009405 13 10 0,000 0,0132044 0,03372588 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0132044 0,03369012 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,0132044 0,03365443 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,0132044 0,03361882 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,0132044 0,03358328 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,0132044 0,03354781 ! endoderm development GO:0007492 16 10 0,000 0,0132044 0,03351243 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,0132044 0,03347711 ! arginine catabolic process GO:0006527 13 10 0,000 0,0132044 0,03344187 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0132044 0,03340671 ! proline metabolic process GO:0006560 13 10 0,000 0,0132044 0,03337162 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,0132044 0,0333366 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,0132044 0,03330166 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,0132044 0,03326679 ! V(D)J recombination GO:0033151 28 10 0,000 0,0132044 0,03323199 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,0132044 0,03319726 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,0132044 0,03316261 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,0132044 0,03312803 ! B cell proliferation GO:0042100 18 10 0,000 0,0132044 0,03309352 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,0132044 0,03305908 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,0132044 0,03302472 ! multicellular organism growth GO:0035264 18 10 0,000 0,0132044 0,03299043 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,0132044 0,0329562 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,0132044 0,03292205 ! epithelial cell development GO:0002064 20 10 0,000 0,0132044 0,03288797 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,0132044 0,03285396 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0132044 0,03282002 ! macroautophagy GO:0016236 17 10 0,000 0,0132044 0,03278615 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,0132044 0,03275235 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,0132044 0,03271862 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,0132044 0,03268496 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,0132044 0,03265137 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,0132044 0,03261784 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0132044 0,03258439 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0132044 0,032551 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0132044 0,03251769 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0132044 0,03248444 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,0132044 0,03245126 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,0132044 0,03241814 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,0132044 0,0323851 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,0132044 0,03235212 ! blastoderm segmentation GO:0007350 18 10 0,000 0,0132044 0,03231921 ! response to dsRNA GO:0043331 20 10 0,000 0,0132044 0,03228636 ! DNA ligation GO:0006266 19 10 0,000 0,0132044 0,03225358 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,0132044 0,03222087 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0132044 0,03218823 ! melanosome localization GO:0032400 16 10 0,000 0,0132044 0,03215565 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,0132044 0,03212313 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,0132044 0,03209069 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,0132044 0,03205831 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0132044 0,03202599 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,0132044 0,03199374 ! mRNA cleavage GO:0006379 17 10 0,000 0,0132044 0,03196155 ! protein sumoylation GO:0016925 15 10 0,000 0,0132044 0,03192943 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0132044 0,03189737 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0132044 0,03186538 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0132044 0,03183345 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,0132044 0,03180158 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,0132044 0,03176978 ! salivary gland development GO:0007431 27 10 0,000 0,0132044 0,03173804 ! prophase GO:0051324 15 10 0,000 0,0132044 0,03170637 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,0132044 0,03167476 ! apical protein localization GO:0045176 15 10 0,000 0,0132044 0,03164321 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,0132044 0,03161172 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,0132044 0,0315803 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,0132044 0,03154894 ! midbrain development GO:0030901 13 10 0,000 0,0132044 0,03151764 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,0132044 0,0314864 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,0132044 0,03145523 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,0132044 0,03142412 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,0132044 0,03139306 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0132044 0,03136207 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0132044 0,03133114 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,0132044 0,03130028 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,0132044 0,03126947 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,0132044 0,03123872 ! oocyte development GO:0048599 17 10 0,000 0,0132044 0,03120804 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0132044 0,03117741 ! blastocyst formation GO:0001825 17 10 0,000 0,0132044 0,03114684 ! cerebellar cortex development GO:0021695 15 10 0,000 0,0132044 0,03111634 ! activation of innate immune response GO:0002218 12 10 0,000 0,0132044 0,03108589 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,0132044 0,0310555 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,0132044 0,03102518 ! response to nicotine GO:0035094 20 10 0,000 0,0132044 0,03099491 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,0132044 0,0309647 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,0132044 0,03093455 ! localization within membrane GO:0051668 20 10 0,000 0,0132044 0,03090446 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01451545 0,03393991 ! respiratory burst GO:0045730 17 11 0,000 0,01451545 0,03390696 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01451545 0,03387407 ! neuron fate specification GO:0048665 17 11 0,000 0,01451545 0,03384125 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01451545 0,03380849 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01451545 0,03377579 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01451545 0,03374316 ! thyroid gland development GO:0030878 26 11 0,000 0,01451545 0,03371059 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01451545 0,03367808 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01451545 0,03364564 ! response to pain GO:0048265 24 11 0,000 0,01451545 0,03361325 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01451545 0,03358093 ! T cell proliferation GO:0042098 26 11 0,000 0,01451545 0,03354867 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01451545 0,03351648 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01451545 0,03348434 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01451545 0,03345227 ! bone resorption GO:0045453 16 11 0,000 0,01451545 0,03342026 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01451545 0,03338831 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01451545 0,03335642 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01451545 0,03332459 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01451545 0,03329282 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01451545 0,03326111 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01451545 0,03322947 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01451545 0,03319788 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01451545 0,03316635 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01451545 0,03313489 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01451545 0,03310348 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01451545 0,03307213 ! lipid digestion GO:0044241 18 11 0,000 0,01451545 0,03304084 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01451545 0,03300961 ! UV protection GO:0009650 19 11 0,000 0,01451545 0,03297844 ! adult heart development GO:0007512 14 11 0,000 0,01451545 0,03294733 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01451545 0,03291628 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01451545 0,03288528 ! temperature homeostasis GO:0001659 17 11 0,000 0,01451545 0,03285435 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01451545 0,03282347 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01451545 0,03279265 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01451545 0,03276189 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01451545 0,03273118 ! regulation of organ growth GO:0046620 13 11 0,000 0,01451545 0,03270053 ! pigment granule localization GO:0051875 20 11 0,000 0,01451545 0,03266994 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01451545 0,03263941 ! vasoconstriction GO:0042310 18 11 0,000 0,01451545 0,03260894 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01451545 0,03257852 ! embryonic axis specification GO:0000578 18 11 0,000 0,01451545 0,03254815 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01451545 0,03251785 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01451545 0,0324876 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01451545 0,03245741 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01451545 0,03242727 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01451545 0,03239719 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01451545 0,03236716 ! zymogen activation GO:0031638 15 11 0,000 0,01451545 0,03233719 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01451545 0,03230728 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01451545 0,03227742 ! nucleosome positioning GO:0016584 15 11 0,000 0,01451545 0,03224762 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01451545 0,03221787 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01451545 0,03218818 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01451545 0,03215854 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01451545 0,03212895 ! acid secretion GO:0046717 18 11 0,000 0,01451545 0,03209942 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01451545 0,03206994 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01451545 0,03204052 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01451545 0,03201115 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01451545 0,03198184 ! oocyte differentiation GO:0009994 18 11 0,000 0,01451545 0,03195258 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01451545 0,03192337 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01451545 0,03189422 ! cholesterol efflux GO:0033344 19 11 0,000 0,01451545 0,03186512 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01451545 0,03183607 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01451545 0,03180708 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01451545 0,03177813 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01451545 0,03174925 ! embryonic gut development GO:0048566 15 11 0,000 0,01451545 0,03172041 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01451545 0,03169162 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01451545 0,03166289 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01451545 0,03163421 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01451545 0,03160558 ! defense response to fungus GO:0050832 13 11 0,000 0,01451545 0,03157701 ! developmental induction GO:0031128 19 11 0,000 0,01451545 0,03154848 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01451545 0,03152001 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01451545 0,03149159 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01451545 0,03146322 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01451545 0,0314349 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01451545 0,03140663 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01451545 0,03137841 ! nucleus localization GO:0051647 19 11 0,000 0,01451545 0,03135024 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01451545 0,03132213 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,0158248 0,03411691 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,0158248 0,03408637 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,0158248 0,03405588 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,0158248 0,03402545 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,0158248 0,03399507 ! virus-host interaction GO:0019048 29 12 0,000 0,0158248 0,03396474 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,0158248 0,03393447 ! cartilage condensation GO:0001502 20 12 0,000 0,0158248 0,03390425 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,0158248 0,03387409 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,0158248 0,03384398 ! protein complex disassembly GO:0043241 27 12 0,000 0,0158248 0,03381392 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0158248 0,03378392 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,0158248 0,03375397 ! hippocampus development GO:0021766 26 12 0,000 0,0158248 0,03372407 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,0158248 0,03369422 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,0158248 0,03366443 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0158248 0,03363469 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,0158248 0,03360501 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,0158248 0,03357537 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,0158248 0,03354579 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,0158248 0,03351626 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,0158248 0,03348678 ! drug transport GO:0015893 16 12 0,000 0,0158248 0,03345736 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,0158248 0,03342798 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,0158248 0,03339866 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,0158248 0,03336939 ! polyamine metabolic process GO:0006595 17 12 0,000 0,0158248 0,03334017 ! focal adhesion formation GO:0048041 35 12 0,000 0,0158248 0,033311 ! mitotic spindle organization GO:0007052 21 12 0,000 0,0158248 0,03328188 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,0158248 0,03325282 ! forebrain cell migration GO:0021885 21 12 0,000 0,0158248 0,0332238 ! asymmetric protein localization GO:0008105 20 12 0,000 0,0158248 0,03319483 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,0158248 0,03316592 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,0158248 0,03313705 ! entry into host cell GO:0030260 32 12 0,000 0,0158248 0,03310824 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,0158248 0,03307947 ! monoamine transport GO:0015844 18 12 0,000 0,0158248 0,03305076 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0158248 0,03302209 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,0158248 0,03299348 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,0158248 0,03296491 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,0158248 0,0329364 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0158248 0,03290793 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,0158248 0,03287951 ! protein homotetramerization GO:0051289 21 12 0,000 0,0158248 0,03285114 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,0158248 0,03282282 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,0158248 0,03279455 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0158248 0,03276633 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,0158248 0,03273815 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,0158248 0,03271003 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0158248 0,03268195 ! cranial nerve development GO:0021545 20 12 0,000 0,0158248 0,03265392 ! fucose catabolic process GO:0019317 22 12 0,000 0,0158248 0,03262594 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,0158248 0,03259801 ! histone acetylation GO:0016573 26 12 0,000 0,0158248 0,03257012 ! histone methylation GO:0016571 26 12 0,000 0,0158248 0,03254228 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,0158248 0,03251449 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0158248 0,03248675 ! gland morphogenesis GO:0022612 29 12 0,000 0,0158248 0,03245906 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,0158248 0,03243141 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,0158248 0,03240381 ! T cell homeostasis GO:0043029 25 12 0,000 0,0158248 0,03237625 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,0158248 0,03234875 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,0158248 0,03232128 ! spleen development GO:0048536 22 12 0,000 0,0158248 0,03229387 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,0158248 0,0322665 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,0158248 0,03223918 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,0158248 0,03221191 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,0158248 0,03218468 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,0158248 0,03215749 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,0158248 0,03213036 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,0158248 0,03210327 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,0158248 0,03207622 ! response to cold GO:0009409 17 12 0,000 0,0158248 0,03204922 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,0158248 0,03202227 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,0158248 0,03199536 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01713246 0,03461016 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01713246 0,03458112 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01713246 0,03455213 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01713246 0,0345232 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01713246 0,03449431 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01713246 0,03446546 ! lipid localization GO:0010876 28 13 0,000 0,01713246 0,03443667 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01713246 0,03440793 ! organelle fusion GO:0048284 32 13 0,000 0,01713246 0,03437923 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01713246 0,03435058 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01713246 0,03432198 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01713246 0,03429342 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01713246 0,03426492 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01713246 0,03423646 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01713246 0,03420805 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01713246 0,03417968 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01713246 0,03415136 ! methionine metabolic process GO:0006555 27 13 0,000 0,01713246 0,03412309 ! plasma membrane organization GO:0007009 24 13 0,000 0,01713246 0,03409487 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01713246 0,03406669 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01713246 0,03403856 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01713246 0,03401047 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01713246 0,03398244 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01713246 0,03395444 ! response to X-ray GO:0010165 25 13 0,000 0,01713246 0,0339265 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01713246 0,0338986 ! exocrine system development GO:0035272 32 13 0,000 0,01713246 0,03387074 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01713246 0,03384294 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01713246 0,03381517 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01713246 0,03378746 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01713246 0,03375978 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01713246 0,03373216 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01713246 0,03370458 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01713246 0,03367704 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01713246 0,03364955 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01713246 0,0336221 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01713246 0,0335947 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01713246 0,03356734 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01713246 0,03354003 ! ribosome assembly GO:0042255 17 13 0,000 0,01713246 0,03351276 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01713246 0,03348554 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01713246 0,03345836 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,01713246 0,03343122 ! chromatin silencing GO:0006342 26 13 0,000 0,01713246 0,03340413 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01713246 0,03337708 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01713246 0,03335008 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01713246 0,03332312 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01713246 0,0332962 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01713246 0,03326933 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01713246 0,0332425 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01713246 0,03321571 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01713246 0,03318897 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01713246 0,03316227 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01713246 0,03313561 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01713246 0,03310899 ! embryonic placenta development GO:0001892 23 13 0,000 0,01713246 0,03308242 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01713246 0,03305589 ! insulin secretion GO:0030073 23 13 0,000 0,01713246 0,0330294 ! actin filament polymerization GO:0030041 24 13 0,000 0,01713246 0,03300296 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01713246 0,03297656 ! acrosome reaction GO:0007340 18 13 0,000 0,01713246 0,0329502 ! rRNA transcription GO:0009303 25 14 0,000 0,01843842 0,03543358 ! lactation GO:0007595 26 14 0,000 0,01843842 0,0354053 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01843842 0,03537707 ! reproductive cellular process GO:0048610 20 14 0,000 0,01843842 0,03534888 ! tRNA modification GO:0006400 20 14 0,000 0,01843842 0,03532073 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01843842 0,03529263 ! regulation of S phase GO:0033261 23 14 0,000 0,01843842 0,03526458 ! water transport GO:0006833 21 14 0,000 0,01843842 0,03523657 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01843842 0,0352086 ! non-recombinational repair GO:0000726 25 14 0,000 0,01843842 0,03518068 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,01843842 0,03515281 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01843842 0,03512497 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01843842 0,03509719 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01843842 0,03506944 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01843842 0,03504174 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01843842 0,03501408 ! palate development GO:0060021 31 14 0,000 0,01843842 0,03498647 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01843842 0,0349589 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01843842 0,03493137 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01843842 0,03490389 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01843842 0,03487645 ! arginine metabolic process GO:0006525 17 14 0,000 0,01843842 0,03484905 ! regulation of heart rate GO:0002027 24 14 0,000 0,01843842 0,0348217 ! organic alcohol transport GO:0015850 29 14 0,000 0,01843842 0,03479439 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01843842 0,03476712 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,01843842 0,03473989 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01843842 0,03471271 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01843842 0,03468557 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01843842 0,03465847 ! L-amino acid transport GO:0015807 30 14 0,000 0,01843842 0,03463141 ! bone mineralization GO:0030282 17 14 0,000 0,01843842 0,0346044 ! stem cell development GO:0048864 43 14 0,000 0,01843842 0,03457743 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01843842 0,0345505 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01843842 0,03452361 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01843842 0,03449677 ! cerebellum development GO:0021549 21 14 0,000 0,01843842 0,03446996 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01843842 0,0344432 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01843842 0,03441648 ! response to gamma radiation GO:0010332 28 14 0,000 0,01843842 0,0343898 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01843842 0,03436316 ! cofactor transport GO:0051181 26 14 0,000 0,01843842 0,03433656 ! NADP metabolic process GO:0006739 24 14 0,000 0,01843842 0,03431001 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01843842 0,03428349 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01843842 0,03425702 ! intestinal absorption GO:0050892 25 14 0,000 0,01843842 0,03423059 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01843842 0,0342042 ! oxygen transport GO:0015671 21 14 0,000 0,01843842 0,03417784 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01843842 0,03415153 ! male genitalia development GO:0030539 24 14 0,000 0,01843842 0,03412526 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01843842 0,03409903 ! regulation of axon extension GO:0030516 37 14 0,000 0,01843842 0,03407284 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,01843842 0,03404669 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01843842 0,03402058 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01974269 0,03639917 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01974269 0,0363713 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,01974269 0,03634347 ! superoxide anion generation GO:0042554 20 15 0,000 0,01974269 0,03631569 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01974269 0,03628794 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01974269 0,03626024 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01974269 0,03623258 ! copper ion transport GO:0006825 20 15 0,000 0,01974269 0,03620497 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01974269 0,03617739 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01974269 0,03614986 ! sulfate transport GO:0008272 23 15 0,000 0,01974269 0,03612237 ! response to cAMP GO:0051591 22 15 0,000 0,01974269 0,03609492 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01974269 0,03606752 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01974269 0,03604015 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01974269 0,03601283 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01974269 0,03598554 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01974269 0,0359583 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01974269 0,0359311 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01974269 0,03590394 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01974269 0,03587683 ! pituitary gland development GO:0021983 29 15 0,000 0,01974269 0,03584975 ! vesicle coating GO:0006901 33 15 0,000 0,01974269 0,03582271 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01974269 0,03579572 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01974269 0,03576876 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01974269 0,03574185 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01974269 0,03571498 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01974269 0,03568814 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01974269 0,03566135 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01974269 0,0356346 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01974269 0,03560788 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01974269 0,03558121 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01974269 0,03555458 ! histone deacetylation GO:0016575 20 15 0,000 0,01974269 0,03552799 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01974269 0,03550143 ! tissue regeneration GO:0042246 26 15 0,000 0,01974269 0,03547492 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01974269 0,03544845 ! water homeostasis GO:0030104 27 15 0,000 0,01974269 0,03542201 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01974269 0,03539562 ! muscle maintenance GO:0046716 26 15 0,000 0,01974269 0,03536926 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01974269 0,03534294 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01974269 0,03531667 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01974269 0,03529043 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01974269 0,03526423 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01974269 0,03523807 ! cell killing GO:0001906 29 15 0,000 0,01974269 0,03521195 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,01974269 0,03518586 ! detection of bacterium GO:0016045 18 15 0,000 0,01974269 0,03515982 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01974269 0,03513381 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01974269 0,03510785 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01974269 0,03508192 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01974269 0,03505603 ! peptide hormone processing GO:0016486 23 15 0,000 0,01974269 0,03503018 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,02104527 0,03731387 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02104527 0,0372864 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,02104527 0,03725896 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02104527 0,03723156 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,02104527 0,03720421 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02104527 0,03717689 ! bone remodeling GO:0046849 27 16 0,000 0,02104527 0,03714962 ! filopodium assembly GO:0046847 32 16 0,000 0,02104527 0,03712238 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02104527 0,03709518 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02104527 0,03706803 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02104527 0,03704091 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02104527 0,03701384 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,02104527 0,0369868 ! startle response GO:0001964 28 16 0,000 0,02104527 0,0369598 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02104527 0,03693284 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,02104527 0,03690592 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02104527 0,03687904 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,02104527 0,0368522 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02104527 0,0368254 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,02104527 0,03679864 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02104527 0,03677192 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02104527 0,03674523 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,02104527 0,03671858 ! response to osmotic stress GO:0006970 25 16 0,000 0,02104527 0,03669198 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,02104527 0,03666541 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,02104527 0,03663888 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02104527 0,03661238 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02104527 0,03658593 ! intermediate filament-based process GO:0045103 32 16 0,000 0,02104527 0,03655951 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,02104527 0,03653314 ! negative regulation of immune response GO:0050777 35 16 0,000 0,02104527 0,0365068 ! axon cargo transport GO:0008088 43 16 0,000 0,02104527 0,0364805 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02104527 0,03645423 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02104527 0,03642801 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,02104527 0,03640182 ! DNA replication initiation GO:0006270 27 16 0,000 0,02104527 0,03637567 ! neuron recognition GO:0008038 35 16 0,000 0,02104527 0,03634955 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02104527 0,03632348 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02104527 0,03629744 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02104527 0,03627144 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,02104527 0,03624547 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,02104527 0,03621955 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02104527 0,03619366 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,02104527 0,03616781 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02104527 0,03614199 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02104527 0,03611621 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02104527 0,03609047 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02104527 0,03606476 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02104527 0,03603909 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02104527 0,03601346 ! defense response to virus GO:0051607 37 16 0,000 0,02104527 0,03598787 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,02234617 0,03818528 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,02234617 0,03815818 ! metencephalon development GO:0022037 30 17 0,000 0,02234617 0,03813112 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,02234617 0,03810409 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,02234617 0,03807711 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,02234617 0,03805016 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,02234617 0,03802325 ! signal complex assembly GO:0007172 41 17 0,000 0,02234617 0,03799638 ! endothelial cell migration GO:0043542 28 17 0,000 0,02234617 0,03796955 ! inositol metabolic process GO:0006020 28 17 0,000 0,02234617 0,03794275 ! gene silencing by RNA GO:0031047 36 17 0,000 0,02234617 0,03791599 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,02234617 0,03788927 ! glial cell development GO:0021782 27 17 0,000 0,02234617 0,03786259 ! limbic system development GO:0021761 36 17 0,000 0,02234617 0,03783594 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,02234617 0,03780934 ! adult walking behavior GO:0007628 33 17 0,000 0,02234617 0,03778277 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,02234617 0,03775623 ! heart looping GO:0001947 30 17 0,000 0,02234617 0,03772974 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,02234617 0,03770328 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,02234617 0,03767686 ! myoblast differentiation GO:0045445 45 17 0,000 0,02234617 0,03765047 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,02234617 0,03762413 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,02234617 0,03759782 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,02234617 0,03757154 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,02234617 0,0375453 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02234617 0,0375191 ! glycine metabolic process GO:0006544 28 17 0,000 0,02234617 0,03749294 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,02234617 0,03746681 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02234617 0,03744072 ! NAD metabolic process GO:0019674 29 17 0,000 0,02234617 0,03741467 ! DNA integration GO:0015074 29 17 0,000 0,02234617 0,03738865 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,02234617 0,03736267 ! regulation of protein binding GO:0043393 33 17 0,000 0,02234617 0,03733672 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,02234617 0,03731081 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,02234617 0,03728494 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,02234617 0,0372591 ! genitalia development GO:0048806 30 17 0,000 0,02234617 0,03723329 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,02234617 0,03720753 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,02234617 0,0371818 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,02234617 0,0371561 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,02234617 0,03713044 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,02234617 0,03710481 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,02234617 0,03707923 ! steroid catabolic process GO:0006706 31 17 0,000 0,02234617 0,03705367 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,02234617 0,03702815 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,02234617 0,03700267 ! gas transport GO:0015669 25 17 0,000 0,02234617 0,03697722 ! organic cation transport GO:0015695 31 17 0,000 0,02234617 0,03695181 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,02234617 0,03692643 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,02234617 0,03690108 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,02234617 0,03687577 ! microspike assembly GO:0030035 36 17 0,000 0,02234617 0,0368505 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,02234617 0,03682526 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,02234617 0,03680005 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,02364537 0,03891298 ! neuron maturation GO:0042551 42 18 0,000 0,02364537 0,03888638 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,02364537 0,03885982 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,02364537 0,03883329 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,02364537 0,0388068 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,02364537 0,03878035 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,02364537 0,03875393 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,02364537 0,03872755 ! memory GO:0007613 31 18 0,000 0,02364537 0,0387012 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02364537 0,03867489 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,02364537 0,03864862 ! patterning of blood vessels GO:0001569 39 18 0,000 0,02364537 0,03862238 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,02364537 0,03859618 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,02364537 0,03857001 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,02364537 0,03854388 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,02364537 0,03851779 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02364537 0,03849173 ! response to retinoic acid GO:0032526 26 18 0,000 0,02364537 0,0384657 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,02364537 0,03843971 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,02364537 0,03841375 ! response to fungus GO:0009620 21 18 0,000 0,02364537 0,03838783 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,02364537 0,03836195 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,02364537 0,0383361 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,02364537 0,03831028 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,02364537 0,0382845 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,02364537 0,03825876 ! vitamin transport GO:0051180 27 18 0,000 0,02364537 0,03823304 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,02364537 0,03820737 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,02364537 0,03818173 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,02364537 0,03815612 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,02364537 0,03813054 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,02364537 0,038105 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,02364537 0,0380795 ! nerve development GO:0021675 28 18 0,000 0,02364537 0,03805403 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,02364537 0,03802859 ! protein secretion GO:0009306 39 19 0,000 0,0249429 0,04008859 ! positive regulation of translation GO:0045727 30 19 0,000 0,0249429 0,04006183 ! negative regulation of defense response GO:0031348 25 19 0,000 0,0249429 0,0400351 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,0249429 0,04000841 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,0249429 0,03998175 ! skin development GO:0043588 36 19 0,000 0,0249429 0,03995514 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,0249429 0,03992855 ! lipid phosphorylation GO:0046834 35 19 0,000 0,0249429 0,039902 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0249429 0,03987549 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,0249429 0,03984901 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,0249429 0,03982257 ! bile acid metabolic process GO:0008206 29 19 0,000 0,0249429 0,03979616 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,0249429 0,03976979 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,0249429 0,03974345 ! cerebral cortex development GO:0021987 36 19 0,000 0,0249429 0,03971715 ! pigmentation during development GO:0048066 41 19 0,000 0,0249429 0,03969088 ! response to vitamin A GO:0033189 27 19 0,000 0,0249429 0,03966465 ! heme metabolic process GO:0042168 36 19 0,000 0,0249429 0,03963845 ! actin filament bundle formation GO:0051017 42 19 0,000 0,0249429 0,03961229 ! neuromuscular junction development GO:0007528 34 19 0,000 0,0249429 0,03958616 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,0249429 0,03956006 ! plasma membrane fusion GO:0045026 28 19 0,000 0,0249429 0,039534 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,0249429 0,03950797 ! peptide cross-linking GO:0018149 37 19 0,000 0,0249429 0,03948198 ! protein export from nucleus GO:0006611 36 19 0,000 0,0249429 0,03945602 ! heart process GO:0003015 30 19 0,000 0,0249429 0,0394301 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,0249429 0,03940421 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,0249429 0,03937836 ! visual learning GO:0008542 36 19 0,000 0,0249429 0,03935253 ! cellular pigmentation GO:0033059 36 19 0,000 0,0249429 0,03932675 ! G1 phase GO:0051318 40 19 0,000 0,0249429 0,03930099 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,0249429 0,03927527 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,0249429 0,03924958 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,0249429 0,03922393 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,0249429 0,03919831 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,0249429 0,03917272 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,0249429 0,03914717 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,0249429 0,03912165 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,0249429 0,03909617 ! cilium assembly GO:0042384 37 19 0,000 0,0249429 0,03907071 ! peptide hormone secretion GO:0030072 31 19 0,000 0,0249429 0,03904529 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,02623874 0,04104708 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,02623874 0,04102041 ! positive regulation of ossification GO:0045778 47 20 0,000 0,02623874 0,04099377 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,02623874 0,04096717 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,02623874 0,0409406 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,02623874 0,04091407 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,02623874 0,04088757 ! cAMP metabolic process GO:0046058 36 20 0,000 0,02623874 0,04086111 ! response to vitamin GO:0033273 31 20 0,000 0,02623874 0,04083468 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,02623874 0,04080828 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,02623874 0,04078192 GO:0010675|regulation of cellular carbohydrate metabolic process, ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,02623874 0,04075559 ! response to alkaloid GO:0043279 38 20 0,000 0,02623874 0,0407293 ! retinoid metabolic process GO:0001523 32 20 0,000 0,02623874 0,04070304 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,02623874 0,04067681 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,02623874 0,04065062 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,02623874 0,04062446 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,02623874 0,04059834 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,02623874 0,04057224 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,02623874 0,04054619 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,02623874 0,04052016 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,02623874 0,04049417 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,02623874 0,04046821 ! body fluid secretion GO:0007589 31 20 0,000 0,02623874 0,04044229 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,02623874 0,0404164 ! peptide secretion GO:0002790 35 20 0,000 0,02623874 0,04039054 ! stem cell differentiation GO:0048863 53 20 0,000 0,02623874 0,04036471 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,02623874 0,04033892 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,02623874 0,04031316 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,02623874 0,04028744 ! sensory perception of pain GO:0019233 30 20 0,000 0,02623874 0,04026174 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,02623874 0,04023608 ! diencephalon development GO:0021536 34 20 0,000 0,02623874 0,04021045 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,02623874 0,04018486 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,02623874 0,0401593 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,02623874 0,04013376 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,02623874 0,04010827 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,02623874 0,0400828 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,02623874 0,04005737 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,02623874 0,04003197 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,02623874 0,0400066 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,02623874 0,03998126 ! regulation of glucose import GO:0046324 29 20 0,000 0,02623874 0,03995596 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,02623874 0,03993068 ! actin filament-based movement GO:0030048 43 20 0,000 0,02623874 0,03990544 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,02623874 0,03988024 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,02623874 0,03985506 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,02623874 0,03982991 ! negative regulation of translation GO:0017148 29 20 0,000 0,02623874 0,0398048 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,02623874 0,03977972 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,02623874 0,03975467 ! regulation of cell killing GO:0031341 42 21 0,000 0,02753291 0,04168922 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,02753291 0,041663 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,02753291 0,04163681 ! hormone secretion GO:0046879 38 21 0,000 0,02753291 0,04161066 ! glycerol metabolic process GO:0006071 34 21 0,000 0,02753291 0,04158454 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,02753291 0,04155845 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,02753291 0,0415324 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,02753291 0,04150637 ! axis specification GO:0009798 38 21 0,000 0,02753291 0,04148038 ! ovarian follicle development GO:0001541 35 21 0,000 0,02753291 0,04145442 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,02753291 0,0414285 ! smooth muscle contraction GO:0006939 46 21 0,000 0,02753291 0,04140261 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,02753291 0,04137675 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,02753291 0,04135092 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,02753291 0,04132512 ! cell aging GO:0007569 44 21 0,000 0,02753291 0,04129936 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,02753291 0,04127363 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,02753291 0,04124793 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,02753291 0,04122226 ! cytolysis GO:0019835 24 21 0,000 0,02753291 0,04119662 ! vasodilation GO:0042311 39 21 0,000 0,02753291 0,04117102 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,02753291 0,04114545 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,02753291 0,04111991 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,02753291 0,0410944 ! oogenesis GO:0048477 36 21 0,000 0,02753291 0,04106892 ! DNA modification GO:0006304 34 21 0,000 0,02753291 0,04104348 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,02753291 0,04101806 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,02753291 0,04099268 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,02753291 0,04096733 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,02753291 0,04094201 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,02753291 0,04091672 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,02753291 0,04089146 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,02753291 0,04086624 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,02753291 0,04084104 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,02753291 0,04081588 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,02753291 0,04079075 ! collagen catabolic process GO:0030574 28 21 0,000 0,02753291 0,04076564 ! sperm-egg recognition GO:0035036 21 21 0,000 0,02753291 0,04074057 ! gut development GO:0048565 39 21 0,000 0,02753291 0,04071553 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,02882539 0,04260067 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,02882539 0,04257452 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,02882539 0,0425484 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,02882539 0,04252231 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,02882539 0,04249626 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,02882539 0,04247024 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,02882539 0,04244424 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,02882539 0,04241828 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,02882539 0,04239236 ! regeneration GO:0031099 41 22 0,000 0,02882539 0,04236646 ! keratinization GO:0031424 28 22 0,000 0,02882539 0,04234059 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,02882539 0,04231476 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,02882539 0,04228896 ! sensory perception of taste GO:0050909 28 22 0,000 0,02882539 0,04226319 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,02882539 0,04223745 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,02882539 0,04221174 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,02882539 0,04218607 ! vacuolar transport GO:0007034 36 22 0,000 0,02882539 0,04216042 ! lysosome organization GO:0007040 41 22 0,000 0,02882539 0,04213481 ! central nervous system neuron development GO:0021954 46 22 0,000 0,02882539 0,04210923 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,02882539 0,04208367 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,02882539 0,04205815 ! fucose metabolic process GO:0006004 39 22 0,000 0,02882539 0,04203266 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,02882539 0,0420072 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,02882539 0,04198178 ! ureteric bud development GO:0001657 43 22 0,000 0,02882539 0,04195638 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,02882539 0,04193101 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,02882539 0,04190568 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,02882539 0,04188037 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,02882539 0,0418551 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,02882539 0,04182985 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,02882539 0,04180464 ! sarcomere organization GO:0045214 30 22 0,000 0,02882539 0,04177945 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,02882539 0,0417543 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,02882539 0,04172918 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,02882539 0,04170409 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,02882539 0,04167902 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,02882539 0,04165399 ! protein stabilization GO:0050821 39 22 0,000 0,02882539 0,04162899 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,0301162 0,04346706 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,0301162 0,043441 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,0301162 0,04341497 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,0301162 0,04338897 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,0301162 0,04336301 ! gluconeogenesis GO:0006094 33 23 0,000 0,0301162 0,04333707 ! viral genome replication GO:0019079 41 23 0,000 0,0301162 0,04331117 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,0301162 0,0432853 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,0301162 0,04325946 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,0301162 0,04323364 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,0301162 0,04320786 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,0301162 0,04318211 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,0301162 0,0431564 ! visual behavior GO:0007632 42 23 0,000 0,0301162 0,04313071 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,0301162 0,04310505 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,0301162 0,04307942 ! response to ethanol GO:0045471 46 23 0,000 0,0301162 0,04305382 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,0301162 0,04302826 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,0301162 0,04300272 ! peroxisome organization GO:0007031 37 23 0,000 0,0301162 0,04297722 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,0301162 0,04295174 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,0301162 0,0429263 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,0301162 0,04290088 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,0301162 0,0428755 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,0301162 0,04285014 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,0301162 0,04282482 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,0301162 0,04279952 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,0301162 0,04277425 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,0301162 0,04274902 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,0301162 0,04272381 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,0301162 0,04269864 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,0301162 0,04267349 ! fatty acid transport GO:0015908 44 23 0,000 0,0301162 0,04264837 ! platelet activation GO:0030168 37 23 0,000 0,0301162 0,04262329 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,0301162 0,04259823 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,0301162 0,0425732 ! hormone transport GO:0009914 40 23 0,000 0,0301162 0,0425482 ! cell-cell recognition GO:0009988 25 23 0,000 0,0301162 0,04252323 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,0301162 0,04249829 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,0301162 0,04247338 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,0301162 0,0424485 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,0301162 0,04242365 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,0301162 0,04239882 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,03140534 0,04418787 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,03140534 0,04416204 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,03140534 0,04413625 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,03140534 0,04411048 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,03140534 0,04408475 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,03140534 0,04405904 ! vesicle docking GO:0048278 47 24 0,000 0,03140534 0,04403337 ! spinal cord development GO:0021510 47 24 0,000 0,03140534 0,04400772 ! vacuole organization GO:0007033 43 24 0,000 0,03140534 0,0439821 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,03140534 0,04395652 ! digestive system process GO:0022600 39 24 0,000 0,03140534 0,04393096 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,03140534 0,04390544 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,03140534 0,04387994 ! regulation of behavior GO:0050795 43 24 0,000 0,03140534 0,04385447 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,03140534 0,04382903 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,03140534 0,04380363 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,03140534 0,04377825 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,03140534 0,0437529 ! membrane depolarization GO:0051899 39 24 0,000 0,03140534 0,04372758 ! pallium development GO:0021543 49 24 0,000 0,03140534 0,04370229 ! pentose metabolic process GO:0019321 35 24 0,000 0,03140534 0,04367703 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,03140534 0,04365179 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,03140534 0,04362659 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,03140534 0,04360142 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,03140534 0,04357627 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,03140534 0,04355116 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,03140534 0,04352607 GO:0033013|tetrapyrrole metabolic process, ! regulation of multi-organism process GO:0043900 36 24 0,000 0,03140534 0,04350101 ! regulation of amine transport GO:0051952 40 24 0,000 0,03140534 0,04347598 ! protein tetramerization GO:0051262 52 24 0,000 0,03140534 0,04345098 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,03269281 0,04520627 ! myelination GO:0042552 45 25 0,000 0,03269281 0,0451803 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,03269281 0,04515437 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,03269281 0,04512846 ! phototransduction GO:0007602 33 25 0,000 0,03269281 0,04510258 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,03269281 0,04507674 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,03269281 0,04505092 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,03269281 0,04502513 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,03269281 0,04499937 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,03269281 0,04497364 ! receptor metabolic process GO:0043112 46 25 0,000 0,03269281 0,04494795 ! chromosome condensation GO:0030261 45 25 0,000 0,03269281 0,04492228 ! response to starvation GO:0042594 42 25 0,000 0,03269281 0,04489664 ! neural crest cell development GO:0014032 54 25 0,000 0,03269281 0,04487102 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,03269281 0,04484544 ! negative regulation of cell development GO:0010721 73 25 0,000 0,03269281 0,04481989 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,03269281 0,04479437 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,03269281 0,04476887 ! interaction with host GO:0051701 62 25 0,000 0,03269281 0,0447434 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,03269281 0,04471797 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,03269281 0,04469256 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,03269281 0,04466718 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,03269281 0,04464183 ! immunoglobulin production GO:0002377 55 25 0,000 0,03269281 0,04461651 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,03269281 0,04459122 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,03269281 0,04456595 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,03269281 0,04454072 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,03269281 0,04451551 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,03269281 0,04449033 ! telomere organization GO:0032200 43 25 0,000 0,03269281 0,04446518 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,03269281 0,04444006 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,03269281 0,04441497 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,03397861 0,04613574 ! embryonic pattern specification GO:0009880 44 26 0,000 0,03397861 0,04610972 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,03397861 0,04608373 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,03397861 0,04605777 ! initiation of viral infection GO:0019059 57 26 0,000 0,03397861 0,04603184 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,03397861 0,04600593 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,03397861 0,04598006 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,03397861 0,04595421 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,03397861 0,04592839 ! molting cycle process GO:0022404 50 26 0,000 0,03397861 0,0459026 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,03397861 0,04587685 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,03397861 0,04585112 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,03397861 0,04582541 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,03397861 0,04579974 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,03397861 0,0457741 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,03397861 0,04574848 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,03397861 0,0457229 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,03397861 0,04569734 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,03397861 0,04567181 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,03397861 0,04564631 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,03397861 0,04562084 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,03397861 0,04559539 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,03397861 0,04556998 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,03397861 0,04554459 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,03397861 0,04551923 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,03397861 0,0454939 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,03397861 0,0454686 ! blastocyst development GO:0001824 49 26 0,000 0,03397861 0,04544332 ! leukocyte proliferation GO:0070661 52 26 0,000 0,03397861 0,04541808 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,03397861 0,04539286 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,03397861 0,04536767 ! neuron fate commitment GO:0048663 48 27 0,000 0,03526274 0,04705611 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,03526274 0,04703002 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,03526274 0,04700397 ! iron ion transport GO:0006826 59 27 0,000 0,03526274 0,04697794 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,03526274 0,04695194 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,03526274 0,04692598 ! protein amino acid acylation GO:0043543 55 27 0,000 0,03526274 0,04690004 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,03526274 0,04687412 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,03526274 0,04684824 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,03526274 0,04682239 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,03526274 0,04679656 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,03526274 0,04677076 ! autophagy GO:0006914 41 27 0,000 0,03526274 0,04674499 ! male gonad development GO:0008584 44 27 0,000 0,03526274 0,04671925 ! response to toxin GO:0009636 47 27 0,000 0,03526274 0,04669354 ! primary neural tube formation GO:0014020 51 27 0,000 0,03526274 0,04666786 ! base-excision repair GO:0006284 41 27 0,000 0,03526274 0,0466422 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,03526274 0,04661657 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,03526274 0,04659097 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,03526274 0,0465654 ! glutathione metabolic process GO:0006749 39 27 0,000 0,03526274 0,04653986 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,03526274 0,04651434 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,03526274 0,04648886 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,03526274 0,0464634 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,03526274 0,04643797 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,03654521 0,04810054 ! circadian rhythm GO:0007623 50 28 0,000 0,03654521 0,04807424 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,03654521 0,04804797 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,03654521 0,04802173 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,03654521 0,04799552 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,03654521 0,04796933 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,03654521 0,04794318 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,03654521 0,04791705 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,03654521 0,04789095 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,03654521 0,04786488 ! synaptogenesis GO:0007416 42 28 0,000 0,03654521 0,04783884 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,03654521 0,04781282 ! lipid oxidation GO:0034440 43 28 0,000 0,03654521 0,04778684 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,03654521 0,04776088 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,03654521 0,04773495 ! translational initiation GO:0006413 65 29 0,000 0,03782602 0,04938112 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,03782602 0,04935434 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,03782602 0,04932759 ! regulation of pH GO:0006885 43 29 0,000 0,03782602 0,04930087 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,03782602 0,04927418 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,03782602 0,04924751 ! catechol metabolic process GO:0009712 54 29 0,000 0,03782602 0,04922088 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,03782602 0,04919427 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,03782602 0,0491677 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,03782602 0,04914115 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,03782602 0,04911463 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,03782602 0,04908814 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,03782602 0,04906167 ! cell fate determination GO:0001709 60 29 0,000 0,03782602 0,04903524 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,03782602 0,04900883 ! detection of light stimulus GO:0009583 38 29 0,000 0,03782602 0,04898246 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,03782602 0,04895611 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,03782602 0,04892979 ! tissue homeostasis GO:0001894 48 29 0,000 0,03782602 0,0489035 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,03782602 0,04887723 ! phenol metabolic process GO:0018958 55 30 0,000 0,03910517 0,05050297 ! zinc ion transport GO:0006829 45 30 0,000 0,03910517 0,05047588 ! membrane docking GO:0022406 61 30 0,000 0,03910517 0,05044881 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,03910517 0,05042177 ! cell junction assembly GO:0034329 78 30 0,000 0,03910517 0,05039477 ! regulation of innate immune response GO:0045088 51 30 0,000 0,03910517 0,05036779 ! acute-phase response GO:0006953 49 30 0,000 0,03910517 0,05034084 ! myofibril assembly GO:0030239 47 30 0,000 0,03910517 0,05031392 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,03910517 0,05028703 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,03910517 0,05026017 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,03910517 0,05023333 ! phospholipid transport GO:0015914 51 30 0,000 0,03910517 0,05020653 ! ensheathment of neurons GO:0007272 57 30 0,000 0,03910517 0,05017975 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,03910517 0,050153 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,03910517 0,05012628 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,03910517 0,05009959 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,03910517 0,05007293 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,04038266 0,05168121 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,04038266 0,05165373 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,04038266 0,05162629 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,04038266 0,05159887 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,04038266 0,05157148 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,04038266 0,05154412 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,04038266 0,05151679 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,04038266 0,05148949 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,04038266 0,05146222 ! ovulation cycle process GO:0022602 49 31 0,000 0,04038266 0,05143498 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,04038266 0,05140776 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,04038266 0,05138058 ! peptide transport GO:0015833 55 31 0,000 0,04038266 0,05135342 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,04038266 0,05132629 ! iron ion homeostasis GO:0055072 54 31 0,000 0,04038266 0,05129919 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,04038266 0,05127212 ! mesoderm formation GO:0001707 69 31 0,000 0,04038266 0,05124508 ! natural killer cell activation GO:0030101 45 31 0,000 0,04038266 0,05121806 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,04038266 0,05119108 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,04038266 0,05116412 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,04038266 0,05113719 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,04038266 0,05111029 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,04038266 0,05108342 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,04165849 0,05266964 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,04165849 0,05264198 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,04165849 0,05261434 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,04165849 0,05258674 ! cholesterol transport GO:0030301 56 32 0,000 0,04165849 0,05255916 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,04165849 0,05253161 ! spliceosome assembly GO:0000245 67 32 0,000 0,04165849 0,0525041 ! spindle organization GO:0007051 46 32 0,000 0,04165849 0,05247661 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,04165849 0,05244915 ! metanephros development GO:0001656 74 32 0,000 0,04165849 0,05242172 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,04165849 0,05239431 ! response to ionizing radiation GO:0010212 65 32 0,000 0,04165849 0,05236694 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,04165849 0,05233959 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,04165849 0,05231228 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,04165849 0,05228499 ! muscle cell development GO:0055001 49 32 0,000 0,04165849 0,05225773 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,04165849 0,0522305 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,04165849 0,05220329 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,04165849 0,05217612 ! ovulation cycle GO:0042698 51 32 0,000 0,04165849 0,05214897 ! peripheral nervous system development GO:0007422 64 32 0,000 0,04165849 0,05212185 ! BMP signaling pathway GO:0030509 64 32 0,000 0,04165849 0,05209476 ! hindbrain development GO:0030902 61 32 0,000 0,04165849 0,0520677 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,04165849 0,05204067 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,04165849 0,05201366 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,04165849 0,05198668 ! gene silencing GO:0016458 65 32 0,000 0,04165849 0,05195973 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,04293267 0,05352124 ! post-embryonic development GO:0009791 69 33 0,000 0,04293267 0,05349352 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,04293267 0,05346584 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,04293267 0,05343818 ! ceramide metabolic process GO:0006672 64 33 0,000 0,04293267 0,05341055 ! formation of primary germ layer GO:0001704 72 33 0,000 0,04293267 0,05338294 ! cell fate specification GO:0001708 52 33 0,000 0,04293267 0,05335537 ! sterol transport GO:0015918 57 33 0,000 0,04293267 0,05332782 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,04293267 0,05330031 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,04293267 0,05327282 ! adult locomotory behavior GO:0008344 59 33 0,000 0,04293267 0,05324536 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,04293267 0,05321793 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,04293267 0,05319052 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,04420519 0,05473891 ! glial cell differentiation GO:0010001 63 34 0,000 0,04420519 0,05471075 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,04420519 0,05468262 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,04420519 0,05465452 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,04420519 0,05462645 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,04420519 0,05459841 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,04420519 0,05457039 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,04420519 0,05454241 ! mismatch repair GO:0006298 46 34 0,000 0,04420519 0,05451445 ! spermatid development GO:0007286 63 34 0,000 0,04420519 0,05448652 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,04420519 0,05445862 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,04420519 0,05443075 ! placenta development GO:0001890 53 34 0,000 0,04420519 0,05440291 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,04420519 0,0543751 ! regulation of muscle development GO:0048634 70 35 0,000 0,04547607 0,05590977 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,04547607 0,05588122 ! negative regulation of secretion GO:0051048 63 35 0,000 0,04547607 0,05585269 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,04547607 0,0558242 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,04547607 0,05579573 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,04547607 0,05576729 ! odontogenesis GO:0042476 66 35 0,000 0,04547607 0,05573888 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,04547607 0,0557105 ! female gonad development GO:0008585 58 35 0,000 0,04547607 0,05568215 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,04547607 0,05565383 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,04547607 0,05562553 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,04547607 0,05559727 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,04547607 0,05556903 ! cytokine production GO:0001816 59 35 0,000 0,04547607 0,05554082 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,04547607 0,05551265 ! neural tube formation GO:0001841 67 35 0,000 0,04547607 0,0554845 ! vesicle localization GO:0051648 64 35 0,000 0,04547607 0,05545637 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,0467453 0,05697527 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,0467453 0,05694643 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,0467453 0,05691761 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,0467453 0,05688882 ! positive regulation of cell development GO:0010720 80 36 0,000 0,0467453 0,05686006 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,0467453 0,05683132 ! regulation of proteolysis GO:0030162 72 36 0,000 0,0467453 0,05680262 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,0467453 0,05677395 ! aerobic respiration GO:0009060 55 36 0,000 0,0467453 0,0567453 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,0467453 0,05671669 ! embryonic organ development GO:0048568 57 36 0,000 0,0467453 0,0566881 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,0467453 0,05665954 ! RNA export from nucleus GO:0006405 56 37 0,000 0,04801288 0,05816666 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,04801288 0,05813739 ! meiosis I GO:0007127 65 37 0,000 0,04801288 0,05810815 ! sister chromatid segregation GO:0000819 58 37 0,000 0,04801288 0,05807893 ! actomyosin structure organization GO:0031032 62 37 0,000 0,04801288 0,05804975 ! organic anion transport GO:0015711 68 37 0,000 0,04801288 0,05802059 ! tissue remodeling GO:0048771 76 37 0,000 0,04801288 0,05799146 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,04801288 0,05796237 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,04801288 0,0579333 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,04801288 0,05790426 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,04801288 0,05787525 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,04801288 0,05784627 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,04801288 0,05781732 ! glycogen metabolic process GO:0005977 61 37 0,000 0,04801288 0,05778839 ! pigment metabolic process GO:0042440 80 37 0,000 0,04801288 0,0577595 ! spermatid differentiation GO:0048515 66 37 0,000 0,04801288 0,05773063 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,04801288 0,0577018 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,04927882 0,05919363 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,04927882 0,0591641 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,04927882 0,05913459 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,04927882 0,05910511 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,04927882 0,05907566 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,04927882 0,05904624 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,04927882 0,05901685 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,04927882 0,05898749 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,04927882 0,05895815 ! lipid homeostasis GO:0055088 67 38 0,000 0,04927882 0,05892885 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,04927882 0,05889958 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,04927882 0,05887033 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,04927882 0,05884112 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,04927882 0,05881193 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,04927882 0,05878277 ! glucan metabolic process GO:0044042 62 38 0,000 0,04927882 0,05875364 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,05054312 0,06023118 ! mammary gland development GO:0030879 86 39 0,000 0,05054312 0,06020136 ! learning GO:0007612 77 39 0,000 0,05054312 0,06017157 ! ear morphogenesis GO:0042471 60 39 0,000 0,05054312 0,06014182 ! organic ether metabolic process GO:0018904 55 39 0,000 0,05054312 0,06011209 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,05054312 0,06008239 ! segmentation GO:0035282 67 39 0,000 0,05054312 0,06005272 ! ion transmembrane transport GO:0034220 66 39 0,000 0,05054312 0,06002308 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,05054312 0,05999346 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,05054312 0,05996388 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,05054312 0,05993433 ! RNA modification GO:0009451 57 39 0,000 0,05054312 0,0599048 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,05054312 0,05987531 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,05180578 0,0613409 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,05180578 0,06131073 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,05180578 0,06128059 ! feeding behavior GO:0007631 59 40 0,000 0,05180578 0,06125047 ! negative regulation of binding GO:0051100 72 40 0,000 0,05180578 0,06122039 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,05180578 0,06119033 ! mesenchymal cell development GO:0014031 87 40 0,000 0,05180578 0,06116031 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,05180578 0,06113031 ! maintenance of protein location GO:0045185 91 40 0,000 0,05180578 0,06110035 ! cytokinesis GO:0000910 72 40 0,000 0,05180578 0,06107041 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,0530668 0,06252631 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,0530668 0,06249571 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,0530668 0,06246513 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,0530668 0,06243459 ! gliogenesis GO:0042063 88 41 0,000 0,0530668 0,06240407 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,0530668 0,06237359 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,0530668 0,06234313 ! T cell differentiation GO:0030217 81 41 0,000 0,0530668 0,0623127 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,0530668 0,06228231 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,0530668 0,06225194 ! female gamete generation GO:0007292 61 41 0,000 0,0530668 0,0622216 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,0530668 0,0621913 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,05432619 0,06363623 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,05432619 0,06360526 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,05432619 0,06357433 ! regulation of tube size GO:0035150 71 42 0,000 0,05432619 0,06354342 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,05432619 0,06351254 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,05432619 0,0634817 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,05432619 0,06345088 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,05432619 0,0634201 ! neuron migration GO:0001764 79 42 0,000 0,05432619 0,06338934 ! regulation of protein secretion GO:0050708 71 42 0,000 0,05432619 0,06335861 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,05432619 0,06332791 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,05558395 0,0647627 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,05558395 0,06473135 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,05558395 0,06470004 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,05558395 0,06466875 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,05558395 0,06463749 ! glucose transport GO:0015758 65 43 0,000 0,05558395 0,06460627 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,05558395 0,06457507 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,05558395 0,06454391 ! neural tube development GO:0021915 77 43 0,000 0,05558395 0,06451277 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,05558395 0,06448166 ! striated muscle contraction GO:0006941 77 43 0,000 0,05558395 0,06445059 ! phagocytosis GO:0006909 90 43 0,000 0,05558395 0,06441954 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,05558395 0,06438853 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,05684007 0,06581194 ! hexose transport GO:0008645 67 44 0,000 0,05684007 0,06578028 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,05684007 0,06574866 ! male sex differentiation GO:0046661 76 44 0,000 0,05684007 0,06571706 ! double-strand break repair GO:0006302 81 44 0,000 0,05684007 0,0656855 ! biopolymer methylation GO:0043414 84 44 0,000 0,05684007 0,06565396 ! B cell differentiation GO:0030183 107 44 0,000 0,05684007 0,06562246 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,05684007 0,06559099 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,05684007 0,06555954 ! developmental growth GO:0048589 82 44 0,000 0,05684007 0,06552813 ! maintenance of location in cell GO:0051651 97 44 0,000 0,05684007 0,06549675 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,05809456 0,06691025 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,05809456 0,06687824 ! leukocyte migration GO:0050900 68 45 0,000 0,05809456 0,06684625 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,05809456 0,0668143 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,05809456 0,06678238 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,05809456 0,06675049 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,05809456 0,06671862 ! icosanoid metabolic process GO:0006690 80 45 0,000 0,05809456 0,06668679 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,05809456 0,06665499 ! cell growth GO:0016049 84 45 0,000 0,05809456 0,06662322 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,05934743 0,06802759 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,05934743 0,0679952 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,05934743 0,06796283 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,05934743 0,0679305 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,05934743 0,0678982 ! pigmentation GO:0043473 100 46 0,000 0,05934743 0,06786593 ! response to insulin stimulus GO:0032868 95 46 0,000 0,05934743 0,06783369 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,05934743 0,06780148 ! positive regulation of defense response GO:0031349 76 47 0,000 0,06059867 0,0691981 ! endosome transport GO:0016197 108 47 0,000 0,06059867 0,06916528 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,06059867 0,06913248 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,06059867 0,06909972 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,06059867 0,06906698 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,06059867 0,06903428 ! JNK cascade GO:0007254 91 47 0,000 0,06059867 0,06900161 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,06059867 0,06896897 ! methylation GO:0032259 90 47 0,000 0,06059867 0,06893636 ! protein homooligomerization GO:0051260 76 47 0,000 0,06059867 0,06890378 ! mitochondrial transport GO:0006839 82 48 0,000 0,06184829 0,07029144 ! Notch signaling pathway GO:0007219 96 48 0,000 0,06184829 0,07025826 ! cellular component disassembly GO:0022411 86 48 0,000 0,06184829 0,0702251 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,06184829 0,07019198 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,06184829 0,07015888 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,06184829 0,07012582 ! activation of caspase activity GO:0006919 84 48 0,000 0,06184829 0,07009279 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,06184829 0,07005979 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,06184829 0,07002682 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,06184829 0,06999388 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,06309629 0,07137267 ! regulation of action potential GO:0001508 95 49 0,000 0,06309629 0,07133913 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,06309629 0,07130562 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,06309629 0,07127215 ! regulation of ion transport GO:0043269 77 49 0,000 0,06309629 0,0712387 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,06309629 0,07120529 ! peptide metabolic process GO:0006518 76 49 0,000 0,06309629 0,0711719 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,06309629 0,07113855 ! endocrine system development GO:0035270 104 49 0,000 0,06309629 0,07110523 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,06309629 0,07107194 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,06309629 0,07103869 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,06309629 0,07100546 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,06434267 0,07237422 ! neuromuscular process GO:0050905 99 50 0,000 0,06434267 0,0723404 ! regulation of ossification GO:0030278 117 50 0,000 0,06434267 0,07230661 ! inner ear development GO:0048839 79 50 0,000 0,06434267 0,07227286 ! histone modification GO:0016570 91 50 0,000 0,06434267 0,07223913 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,06434267 0,07220544 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,06434267 0,07217178 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,06434267 0,07213815 ! positive regulation of binding GO:0051099 78 51 0,000 0,06558743 0,07349947 ! viral infectious cycle GO:0019058 99 51 0,000 0,06558743 0,07346525 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,06558743 0,07343107 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,06558743 0,07339691 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,06558743 0,07336279 ! excretion GO:0007588 83 51 0,000 0,06558743 0,0733287 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,06558743 0,07329464 ! chromatin remodeling GO:0006338 109 51 0,000 0,06558743 0,07326061 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,06558743 0,07322662 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,06558743 0,07319265 ! regulation of cell shape GO:0008360 125 51 0,000 0,06558743 0,07315872 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,06558743 0,07312482 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,06683058 0,07447632 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,06683058 0,07444184 ! membrane fusion GO:0006944 110 52 0,000 0,06683058 0,07440739 ! positive regulation of growth GO:0045927 90 52 0,000 0,06683058 0,07437298 ! covalent chromatin modification GO:0016569 101 52 0,000 0,06683058 0,07433859 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,06683058 0,07430424 ! amino acid activation GO:0043038 92 52 0,000 0,06683058 0,07426992 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,06683058 0,07423563 ! synapse organization GO:0050808 85 52 0,000 0,06683058 0,07420137 ! RNA catabolic process GO:0006401 93 53 0,000 0,06807212 0,07554498 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,06807212 0,07551015 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,06807212 0,07547535 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,06807212 0,07544059 ! cell maturation GO:0048469 100 53 0,000 0,06807212 0,07540585 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,06807212 0,07537115 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,06807212 0,07533648 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,06931204 0,07667346 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,06931204 0,07663822 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,06931204 0,07660302 ! cell recognition GO:0008037 85 54 0,000 0,06931204 0,07656785 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,06931204 0,07653271 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,06931204 0,0764976 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,06931204 0,07646253 ! chloride transport GO:0006821 90 55 0,000 0,07055036 0,07779293 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,07055036 0,07775729 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,07055036 0,07772169 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,07055036 0,07768612 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,07055036 0,07765058 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,07055036 0,07761507 ! gastrulation GO:0007369 112 55 0,000 0,07055036 0,0775796 ! heart morphogenesis GO:0003007 97 55 0,000 0,07055036 0,07754416 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,07055036 0,07750875 ! RNA elongation GO:0006354 79 55 0,000 0,07055036 0,07747337 ! nuclear export GO:0051168 97 55 0,000 0,07055036 0,07743803 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,07055036 0,07740272 ! regulation of actin filament length GO:0030832 105 56 0,000 0,07178707 0,07872365 ! sensory perception of smell GO:0007608 80 56 0,000 0,07178707 0,07868779 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,07178707 0,07865195 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,07178707 0,07861615 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,07178707 0,07858039 ! regulation of DNA replication GO:0006275 101 56 0,000 0,07178707 0,07854465 ! proton transport GO:0015992 94 56 0,000 0,07178707 0,07850895 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,07178707 0,07847328 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,07302218 0,07978717 ! muscle fiber development GO:0048747 112 57 0,000 0,07302218 0,07975095 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,07302218 0,07971477 ! lipid modification GO:0030258 97 57 0,000 0,07302218 0,07967862 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,07302218 0,0796425 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,07302218 0,07960641 ! maintenance of location GO:0051235 118 57 0,000 0,07302218 0,07957036 ! hydrogen transport GO:0006818 97 58 0,000 0,07425568 0,08087785 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,07425568 0,08084125 ! regulation of endocytosis GO:0030100 91 58 0,000 0,07425568 0,08080469 ! adult behavior GO:0030534 99 58 0,000 0,07425568 0,08076816 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,07425568 0,08073166 ! positive regulation of secretion GO:0051047 95 59 0,000 0,07548758 0,08203393 ! regulation of cellular component size GO:0032535 109 59 0,000 0,07548758 0,08199689 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,07548758 0,08195989 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,07548758 0,08192292 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,07548758 0,08188599 ! DNA catabolic process GO:0006308 86 59 0,000 0,07548758 0,08184909 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,07548758 0,08181222 ! establishment of organelle localization GO:0051656 109 59 0,000 0,07548758 0,08177538 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,07671789 0,08307076 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,07671789 0,08303339 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,07671789 0,08299606 ! regulation of heart contraction GO:0008016 110 60 0,000 0,07671789 0,08295876 ! camera-type eye development GO:0043010 116 60 0,000 0,07671789 0,08292149 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,07671789 0,08288425 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,07671789 0,08284705 ! kidney development GO:0001822 122 60 0,000 0,07671789 0,08280989 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,07794659 0,08409843 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,07794659 0,08406074 ! mesoderm development GO:0007498 119 61 0,000 0,07794659 0,08402308 ! tRNA processing GO:0008033 89 61 0,000 0,07794659 0,08398545 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,07794659 0,08394785 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,07794659 0,08391029 ! ear development GO:0043583 103 62 0,000 0,07917371 0,08519318 ! viral reproductive process GO:0022415 126 62 0,000 0,07917371 0,08515509 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,07917371 0,08511704 ! gonad development GO:0008406 98 62 0,000 0,07917371 0,08507903 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,07917371 0,08504105 ! regulation of mitosis GO:0007088 105 63 0,000 0,08039923 0,08631885 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,08039923 0,08628035 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,08039923 0,08624188 ! detection of external stimulus GO:0009581 91 63 0,000 0,08039923 0,08620345 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,08039923 0,08616505 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,08039923 0,08612669 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,08162316 0,0873989 ! cell redox homeostasis GO:0045454 102 64 0,000 0,08162316 0,08736002 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,08162316 0,08732118 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,08162316 0,08728237 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,08162316 0,08724359 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,08162316 0,08720485 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,0828455 0,0884715 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,0828455 0,08843225 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,0828455 0,08839303 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,0828455 0,08835385 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,0828455 0,0883147 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,08406626 0,08957636 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,08406626 0,08953671 ! extracellular matrix organization GO:0030198 133 66 0,000 0,08406626 0,08949709 ! secondary metabolic process GO:0019748 116 66 0,000 0,08406626 0,08945751 ! developmental maturation GO:0021700 116 66 0,000 0,08406626 0,08941796 ! cell projection assembly GO:0030031 120 66 0,000 0,08406626 0,08937845 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,08528543 0,09063461 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,08528543 0,09059459 ! activation of MAPK activity GO:0000187 115 67 0,000 0,08528543 0,09055461 ! lung development GO:0030324 144 67 0,000 0,08528543 0,09051467 ! chromosome segregation GO:0007059 113 67 0,000 0,08528543 0,09047476 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,08528543 0,09043488 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,08528543 0,09039505 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,08528543 0,09035524 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,08528543 0,09031547 ! adaptive immune response GO:0002250 119 67 0,000 0,08528543 0,09027574 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,08528543 0,09023604 ! amino acid transport GO:0006865 125 68 0,000 0,08650302 0,09148408 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,08650302 0,09144388 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,08650302 0,09140372 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,08650302 0,0913636 ! viral reproduction GO:0016032 134 68 0,000 0,08650302 0,09132351 ! regulation of lipase activity GO:0060191 130 68 0,000 0,08650302 0,09128345 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,08650302 0,09124343 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,08771903 0,09248554 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,08771903 0,09244503 ! urogenital system development GO:0001655 137 69 0,000 0,08771903 0,09240455 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,08771903 0,09236411 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,08771903 0,09232371 ! antigen processing and presentation GO:0019882 104 69 0,000 0,08771903 0,09228334 ! appendage morphogenesis GO:0035107 135 70 0,000 0,08893346 0,09352007 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,08893346 0,09347921 ! amine catabolic process GO:0009310 117 71 0,000 0,09014632 0,09471268 ! reproductive structure development GO:0048608 113 71 0,000 0,09014632 0,09467134 ! appendage development GO:0048736 136 71 0,000 0,09014632 0,09463004 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,09014632 0,09458877 ! B cell activation GO:0042113 160 71 0,000 0,09014632 0,09454754 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,09014632 0,09450634 ! regulation of immune effector process GO:0002697 137 71 0,000 0,09014632 0,09446518 ! acute inflammatory response GO:0002526 113 72 0,000 0,0913576 0,09569281 ! regulation of caspase activity GO:0043281 122 72 0,000 0,0913576 0,09565117 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,0913576 0,09560956 ! carbohydrate transport GO:0008643 110 72 0,000 0,0913576 0,09556799 ! respiratory system development GO:0060541 153 72 0,000 0,0913576 0,09552646 ! learning or memory GO:0007611 147 73 0,000 0,09256731 0,09674933 ! regulation of blood pressure GO:0008217 125 73 0,000 0,09256731 0,09670732 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,09256731 0,09666534 ! axon guidance GO:0007411 139 73 0,000 0,09256731 0,0966234 ! fertilization GO:0009566 90 73 0,000 0,09256731 0,0965815 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,09377545 0,09779962 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,09377545 0,09775725 ! neurotransmitter transport GO:0006836 123 74 0,000 0,09377545 0,09771491 ! meiosis GO:0007126 121 74 0,000 0,09377545 0,09767261 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,09377545 0,09763035 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,09377545 0,09758812 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,09377545 0,09754593 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,09377545 0,09750377 ! organelle localization GO:0051640 136 74 0,000 0,09377545 0,09746165 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,09498202 0,09867303 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,09498202 0,09863044 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,09498202 0,09858789 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,09498202 0,09854538 ! meiotic cell cycle GO:0051321 122 75 0,000 0,09498202 0,0985029 ! rhythmic process GO:0048511 128 75 0,000 0,09498202 0,09846046 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,09498202 0,09841806 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,09618702 0,09962375 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,09618702 0,09958088 ! defense response to bacterium GO:0042742 89 76 0,000 0,09618702 0,09953805 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,09618702 0,09949526 ! regulation of catabolic process GO:0009894 161 76 0,000 0,09618702 0,0994525 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,09739046 0,10065354 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,09739046 0,10061033 ! blood coagulation GO:0007596 146 78 0,000 0,09859234 0,10180823 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,09859234 0,10176455 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,09859234 0,10172091 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,09859234 0,10167731 ! protein oligomerization GO:0051259 139 78 0,000 0,09859234 0,10163375 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,09979265 0,10282703 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,09979265 0,10278302 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,09979265 0,10273904 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,09979265 0,10269509 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,09979265 0,10265119 ! muscle cell differentiation GO:0042692 159 80 0,000 0,10099141 0,10383989 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,10099141 0,10379553 ! protein import into nucleus GO:0006606 158 80 0,000 0,10099141 0,10375121 ! inorganic anion transport GO:0015698 138 80 0,000 0,10099141 0,10370693 ! T cell activation GO:0042110 168 81 0,000 0,10218861 0,10489155 ! response to hypoxia GO:0001666 171 81 0,000 0,10218861 0,10484682 ! digestion GO:0007586 112 81 0,000 0,10218861 0,10480213 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,10218861 0,10475748 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,10218861 0,10471286 ! nuclear import GO:0051170 161 81 0,000 0,10218861 0,10466829 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,10218861 0,10462375 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,10338426 0,10580286 ! response to drug GO:0042493 143 82 0,000 0,10338426 0,10575788 ! response to nutrient GO:0007584 125 82 0,000 0,10338426 0,10571293 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,10338426 0,10566803 ! response to oxygen levels GO:0070482 176 83 0,000 0,10457836 0,10684311 ! hemostasis GO:0007599 158 84 0,000 0,1057709 0,10801561 ! negative regulation of transport GO:0051051 153 84 0,000 0,1057709 0,10796979 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,1057709 0,107924 ! nucleosome assembly GO:0006334 122 85 0,000 0,10696189 0,10909297 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,10696189 0,10904675 ! amine biosynthetic process GO:0009309 138 86 0,000 0,10815134 0,11021268 ! chromatin assembly GO:0031497 124 86 0,000 0,10815134 0,11016602 ! tube morphogenesis GO:0035239 176 86 0,000 0,10815134 0,1101194 ! amine transport GO:0015837 155 86 0,000 0,10815134 0,11007281 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,10933925 0,11123477 ! protein localization in nucleus GO:0034504 176 87 0,000 0,10933925 0,11118776 ! regulation of protein transport GO:0051223 154 87 0,000 0,10933925 0,11114078 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 0,000 0,11052561 0,11229925 ! gland development GO:0048732 206 88 0,000 0,11052561 0,11225184 ! regulation of neurological system process GO:0031644 148 88 0,000 0,11052561 0,11220448 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,11052561 0,11215716 ! cellular defense response GO:0006968 114 89 0,000 0,11171043 0,11331167 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,11171043 0,11326392 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,11171043 0,11321621 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,11289371 0,11436727 ! sex differentiation GO:0007548 145 90 0,000 0,11289371 0,11431914 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,11289371 0,11427104 ! sterol metabolic process GO:0016125 152 91 0,000 0,11407546 0,11541865 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,11407546 0,11537013 ! regulation of defense response GO:0031347 149 92 0,000 0,11525567 0,11651476 ! nucleosome organization GO:0034728 138 92 0,000 0,11525567 0,11646583 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,11525567 0,11641693 ! vitamin metabolic process GO:0006766 139 92 0,000 0,11525567 0,11636808 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,11643434 0,11750882 ! regulation of membrane potential GO:0042391 164 93 0,000 0,11643434 0,11745955 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,11643434 0,11741032 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,11761149 0,11854765 ! female pregnancy GO:0007565 164 94 0,000 0,11761149 0,11849801 ! transcription initiation GO:0006352 153 94 0,000 0,11761149 0,11844841 ! regulation of T cell activation GO:0050863 158 94 0,000 0,11761149 0,11839885 ! forebrain development GO:0030900 188 95 0,000 0,11878711 0,11953232 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,11878711 0,11948235 ! leukocyte differentiation GO:0002521 202 96 0,000 0,11996119 0,12061289 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,11996119 0,1205625 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,11996119 0,12051216 ! positive regulation of immune response GO:0050778 156 96 0,000 0,11996119 0,12046187 ! detection of stimulus GO:0051606 151 96 0,000 0,11996119 0,12041161 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,12113376 0,12153787 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,12113376 0,12148721 ! protein ubiquitination GO:0016567 217 97 0,000 0,12113376 0,12143659 ! hormone metabolic process GO:0042445 157 97 0,000 0,12113376 0,12138602 ! regulation of protein localization GO:0032880 176 97 0,000 0,12113376 0,12133548 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,1223048 0,12245749 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,1223048 0,12240655 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,12347432 0,12352566 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,12347432 0,12347432 GO:0060538|skeletal muscle organ development,