pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/374291-4-real-IPC-NIBC-129-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! polyol catabolic process GO:0046174 9 5 2,000 1,531E-08 3,741E-05 GO:0019405|alditol catabolic process, ! cellular carbohydrate catabolic process GO:0044275 17 13 2,000 4,351E-07 5,315E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 6,355E-07 5,175E-04 ! fructose metabolic process GO:0006000 25 16 2,000 8,499E-07 5,191E-04 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 2,000 2,01E-06 9,822E-04 ! alcohol catabolic process GO:0046164 142 87 3,000 3,49E-06 1,421E-03 ! osteoblast differentiation GO:0001649 63 26 2,000 3,914E-06 1,366E-03 ! alditol metabolic process GO:0019400 44 26 2,000 3,914E-06 1,195E-03 ! sperm motility GO:0030317 37 28 2,000 4,923E-06 1,336E-03 ! hexose biosynthetic process GO:0019319 53 32 2,000 7,429E-06 1,815E-03 ! monosaccharide biosynthetic process GO:0046364 57 36 2,000 1,066E-05 2,367E-03 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 2,000 1,159E-05 2,36E-03 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! DNA replication, synthesis of RNA primer GO:0006269 8 5 1,000 1,36E-05 2,556E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 1,36E-05 2,373E-03 ! alcohol biosynthetic process GO:0046165 65 42 2,000 1,705E-05 2,778E-03 ! photoreceptor cell development GO:0042461 10 6 1,000 2,038E-05 3,112E-03 GO:0046530|photoreceptor cell differentiation, ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 1,000 2,038E-05 2,929E-03 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! polyol metabolic process GO:0019751 77 45 2,000 2,103E-05 2,854E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 2,248E-05 2,89E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 3,799E-05 4,641E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 1,000 3,799E-05 4,42E-03 ! response to UV GO:0009411 120 55 2,000 3,856E-05 4,282E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 6,097E-05 6,476E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 6,097E-05 6,206E-03 ! Golgi vesicle budding GO:0048194 26 11 1,000 7,446E-05 7,277E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 1,000 7,446E-05 6,997E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 8,929E-05 8,079E-03 ! establishment of cell polarity GO:0030010 21 12 1,000 8,929E-05 7,79E-03 ! regulation of adenylate cyclase activity GO:0045761 165 83 2,000 1,32E-04 0,01111767 ! regulation of cyclase activity GO:0031279 168 85 2,000 1,416E-04 0,01153391 ! regulation of cAMP biosynthetic process GO:0030817 173 86 2,000 1,466E-04 0,0115558 ! regulation of lyase activity GO:0051339 169 86 2,000 1,466E-04 0,01119468 ! regulation of cAMP metabolic process GO:0030814 182 89 2,000 1,623E-04 0,01201637 ! response to unfolded protein GO:0006986 139 90 2,000 1,678E-04 0,01205521 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 2,000 1,734E-04 0,01210007 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 2,000 1,734E-04 0,01176396 ! bone development GO:0060348 206 92 2,000 1,79E-04 0,01182212 ! membrane budding GO:0006900 42 17 1,000 1,833E-04 0,01178432 ! carbohydrate biosynthetic process GO:0016051 158 94 2,000 1,908E-04 0,01195216 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 2,000 1,969E-04 0,01202349 ! response to protein stimulus GO:0051789 158 96 2,000 2,03E-04 0,01209869 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 2,158E-04 0,01255181 ! regulation of nucleotide metabolic process GO:0006140 197 98 2,000 2,158E-04 0,01225991 ! cellular response to unfolded protein GO:0034620 35 20 1,000 2,555E-04 0,01418644 GO:0030968|endoplasmic reticulum unfolded protein response, ! cell-cell junction organization GO:0045216 43 20 1,000 2,555E-04 0,01387118 ! positive regulation of B cell activation GO:0050871 42 22 1,000 3,102E-04 0,01647311 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 3,395E-04 0,01764487 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 3,7E-04 0,01883381 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 4,019E-04 0,02003873 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 4,019E-04 0,01963795 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 4,351E-04 0,02084168 GO:0045936|negative regulation of phosphate metabolic process, ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 4,351E-04 0,02044088 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 5,053E-04 0,02329082 ! fat cell differentiation GO:0045444 57 28 1,000 5,053E-04 0,02285951 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 5,423E-04 0,02408834 ! regulation of B cell activation GO:0050864 55 30 1,000 5,806E-04 0,02532908 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 6,202E-04 0,02658098 ! eye morphogenesis GO:0048592 65 31 1,000 6,202E-04 0,02612268 ! response to heat GO:0009408 54 31 1,000 6,202E-04 0,02567993 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 1,000 8,371E-04 0,03408443 ! protein targeting to membrane GO:0006612 75 36 1,000 8,371E-04 0,03352567 ! cell junction organization GO:0034330 96 37 1,000 8,843E-04 0,03484369 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 9,327E-04 0,03616856 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 9,824E-04 0,03749985 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! establishment or maintenance of cell polarity GO:0007163 96 41 1,000 1,086E-03 0,04079826 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 1,307E-03 0,04836514 ! ATP synthesis coupled electron transport GO:0042773 69 45 1,000 1,307E-03 0,04764327 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! glycolysis GO:0006096 71 46 1,000 1,365E-03 0,04903968 ! positive regulation of cell cycle GO:0045787 96 48 1,000 1,485E-03 0,05259281 ! response to calcium ion GO:0051592 94 49 1,000 1,547E-03 0,05400709 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 1,547E-03 0,05324643 ! response to temperature stimulus GO:0009266 84 51 1,000 1,675E-03 0,05684203 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 1,741E-03 0,05826231 ! respiratory electron transport chain GO:0022904 83 53 1,000 1,808E-03 0,05968426 ! vesicle organization GO:0016050 127 53 1,000 1,808E-03 0,05888847 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 1,808E-03 0,05811362 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of translational initiation GO:0006446 87 54 1,000 1,876E-03 0,05952049 ! glucose catabolic process GO:0006007 88 56 1,000 2,016E-03 0,0631385 ! aging GO:0007568 112 58 1,000 2,161E-03 0,06681355 ! negative regulation of cell growth GO:0030308 142 67 1,000 2,871E-03 0,08765905 ! hexose catabolic process GO:0019320 113 68 1,000 2,955E-03 0,08913378 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 2,955E-03 0,08804678 ! negative regulation of cell size GO:0045792 144 69 1,000 3,041E-03 0,08951569 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 3,041E-03 0,08845002 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 3,041E-03 0,08740943 ! negative regulation of kinase activity GO:0033673 145 70 1,000 3,128E-03 0,08886762 ! actin filament organization GO:0007015 167 72 1,000 3,306E-03 0,0928363 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 3,306E-03 0,09178134 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 3,306E-03 0,09075009 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 3,488E-03 0,09469123 ! negative regulation of transferase activity GO:0051348 155 74 1,000 3,488E-03 0,09365066 ! eye development GO:0001654 155 75 1,000 3,581E-03 0,09509958 ! positive regulation of ligase activity GO:0051351 130 77 1,000 3,771E-03 0,09904816 ! monosaccharide catabolic process GO:0046365 125 77 1,000 3,771E-03 0,09799445 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 3,867E-03 0,09944033 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 3,964E-03 0,10088513 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 4,163E-03 0,10484115 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 4,366E-03 0,1088294 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 1,000 4,469E-03 0,11027538 ! regulation of ligase activity GO:0051340 147 84 1,000 4,469E-03 0,10917262 ! negative regulation of growth GO:0045926 168 85 1,000 4,573E-03 0,11061377 ! positive regulation of cell activation GO:0050867 161 86 1,000 4,678E-03 0,11205354 GO:0002696|positive regulation of leukocyte activation, ! mitochondrion organization GO:0007005 159 87 1,000 4,785E-03 0,11349191 ! cellular respiration GO:0045333 143 88 1,000 4,893E-03 0,11492886 ! response to inorganic substance GO:0010035 173 90 1,000 5,111E-03 0,11892029 ! oxidative phosphorylation GO:0006119 152 90 1,000 5,111E-03 0,1177984 ! positive regulation of protein modification process GO:0031401 156 90 1,000 5,111E-03 0,11669748 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 5,447E-03 0,12322201 GO:0010498|proteasomal protein catabolic process, ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 5,895E-03 0,13211374 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 5,895E-03 0,13091271 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 5,895E-03 0,12973331 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 5,895E-03 0,12857498 ! positive regulation of helicase activity GO:0051096 12 5 0,000 5,895E-03 0,12743715 ! neuron fate determination GO:0048664 7 5 0,000 5,895E-03 0,12631928 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 5,895E-03 0,12522085 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 5,895E-03 0,12414136 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 5,895E-03 0,12308032 ! polyol transport GO:0015791 12 5 0,000 5,895E-03 0,12203727 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 5,895E-03 0,12101175 ! response to superoxide GO:0000303 10 5 0,000 5,895E-03 0,12000331 ! negative regulation of bone resorption GO:0045779 10 5 0,000 5,895E-03 0,11901155 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 5,895E-03 0,11803605 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 5,895E-03 0,1170764 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 5,895E-03 0,11613224 ! female meiosis GO:0007143 10 5 0,000 5,895E-03 0,11520318 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 5,895E-03 0,11428887 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 5,895E-03 0,11338896 ! hypothalamus development GO:0021854 9 5 0,000 5,895E-03 0,11250311 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 5,895E-03 0,11163099 ! cobalt ion transport GO:0006824 11 5 0,000 5,895E-03 0,11077229 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 5,895E-03 0,1099267 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 5,895E-03 0,10909392 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 5,895E-03 0,10827367 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 5,895E-03 0,10746565 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 5,895E-03 0,10666961 ! embryonic camera-type eye development GO:0031076 12 5 0,000 5,895E-03 0,10588528 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 5,895E-03 0,10511239 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 5,895E-03 0,10435071 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 5,895E-03 0,10359998 ! transposition GO:0032196 9 5 0,000 5,895E-03 0,10285998 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 5,895E-03 0,10213048 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 5,895E-03 0,10141125 ! negative chemotaxis GO:0050919 16 5 0,000 5,895E-03 0,10070208 ! positive regulation of histone modification GO:0031058 6 5 0,000 5,895E-03 0,10000276 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 5,895E-03 0,09931309 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 5,895E-03 0,09863286 ! behavioral response to pain GO:0048266 10 5 0,000 5,895E-03 0,09796189 ! clathrin coat assembly GO:0048268 15 5 0,000 5,895E-03 0,09729998 ! Notch receptor processing GO:0007220 11 5 0,000 5,895E-03 0,09664696 ! regulation of dopamine uptake GO:0051584 9 5 0,000 5,895E-03 0,09600265 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 5,895E-03 0,09536687 ! micturition GO:0060073 9 5 0,000 5,895E-03 0,09473946 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 5,895E-03 0,09412025 ! copulation GO:0007620 9 5 0,000 5,895E-03 0,09350908 ! glial cell fate commitment GO:0021781 14 5 0,000 5,895E-03 0,09290579 ! protein maturation by protein folding GO:0022417 14 5 0,000 5,895E-03 0,09231024 ! bioluminescence GO:0008218 9 5 0,000 5,895E-03 0,09172228 ! spermidine metabolic process GO:0008216 7 5 0,000 5,895E-03 0,09114176 ! regulation of potassium ion transport GO:0043266 10 5 0,000 5,895E-03 0,09056854 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 5,895E-03 0,09000249 ! apoptotic cell clearance GO:0043277 23 5 0,000 5,895E-03 0,08944346 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 5,895E-03 0,08889134 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 5,895E-03 0,088346 ! lipoprotein particle clearance GO:0034381 10 5 0,000 5,895E-03 0,0878073 ! grooming behavior GO:0007625 6 5 0,000 5,895E-03 0,08727514 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 5,895E-03 0,08674938 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 5,895E-03 0,08622993 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 5,895E-03 0,08571665 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 5,895E-03 0,08520945 ! response to protozoan GO:0001562 13 5 0,000 5,895E-03 0,08470822 ! positive regulation of glycolysis GO:0045821 13 5 0,000 5,895E-03 0,08421285 ! lymph vessel development GO:0001945 10 5 0,000 5,895E-03 0,08372324 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 5,895E-03 0,08323929 ! endochondral ossification GO:0001958 17 5 0,000 5,895E-03 0,08276091 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 5,895E-03 0,08228799 ! single strand break repair GO:0000012 8 5 0,000 5,895E-03 0,08182044 ! parathyroid gland development GO:0060017 14 5 0,000 5,895E-03 0,08135818 ! anagen GO:0042640 7 5 0,000 5,895E-03 0,08090111 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 5,895E-03 0,08044915 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 5,895E-03 0,08000221 ! cytokine secretion GO:0050663 15 5 0,000 5,895E-03 0,07956021 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 5,895E-03 0,07912306 ! ceramide catabolic process GO:0046514 7 5 0,000 5,895E-03 0,0786907 ! skeletal myofibril assembly GO:0014866 12 5 0,000 5,895E-03 0,07826303 ! smooth muscle tissue development GO:0048745 32 5 0,000 5,895E-03 0,07783999 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 5,895E-03 0,07742149 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 5,895E-03 0,07700747 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 5,895E-03 0,07659786 ! cardiac muscle fiber development GO:0048739 12 5 0,000 5,895E-03 0,07619258 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 5,895E-03 0,07579157 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 5,895E-03 0,07539475 ! neutrophil mediated immunity GO:0002446 7 5 0,000 5,895E-03 0,07500207 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 5,895E-03 0,07461346 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 5,895E-03 0,07422885 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 5,895E-03 0,07384819 ! glycine biosynthetic process GO:0006545 7 5 0,000 5,895E-03 0,07347142 ! microvillus organization GO:0032528 8 5 0,000 5,895E-03 0,07309847 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 5,895E-03 0,07272928 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 5,895E-03 0,07236381 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 5,895E-03 0,07200199 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 5,895E-03 0,07164377 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 5,895E-03 0,0712891 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 5,895E-03 0,07093792 ! polyol biosynthetic process GO:0046173 6 5 0,000 5,895E-03 0,07059019 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 5,895E-03 0,07024584 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 5,895E-03 0,06990484 ! muscle cell migration GO:0014812 8 5 0,000 5,895E-03 0,06956714 ! mitochondrial fission GO:0000266 8 5 0,000 5,895E-03 0,06923268 ! sister chromatid cohesion GO:0007062 15 5 0,000 5,895E-03 0,06890142 ! response to tumor necrosis factor GO:0034612 10 5 0,000 5,895E-03 0,06857332 ! mRNA transcription GO:0009299 10 5 0,000 5,895E-03 0,06824833 ! nerve growth factor processing GO:0032455 9 5 0,000 5,895E-03 0,0679264 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 5,895E-03 0,0676075 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 5,895E-03 0,06729158 ! anaerobic glycolysis GO:0019642 6 5 0,000 5,895E-03 0,06697859 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 5,895E-03 0,06666851 ! monocyte activation GO:0042117 10 5 0,000 5,895E-03 0,06636128 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 5,895E-03 0,06605687 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 5,895E-03 0,06575524 ! response to food GO:0032094 6 5 0,000 5,895E-03 0,06545635 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 5,895E-03 0,06516017 ! positive regulation of transporter activity GO:0032411 8 5 0,000 5,895E-03 0,06486666 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 5,895E-03 0,06457577 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 5,895E-03 0,06428749 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 5,895E-03 0,06400177 ! forebrain neuron development GO:0021884 13 5 0,000 5,895E-03 0,06371857 ! lipoprotein catabolic process GO:0042159 11 5 0,000 5,895E-03 0,06343788 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 5,895E-03 0,06315964 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 5,895E-03 0,06288383 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 5,895E-03 0,06261043 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 5,895E-03 0,06233938 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 5,895E-03 0,06207068 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 5,895E-03 0,06180428 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 5,895E-03 0,06154016 ! lipid glycosylation GO:0030259 7 5 0,000 5,895E-03 0,06127829 ! nucleobase transport GO:0015851 6 5 0,000 5,895E-03 0,06101863 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,895E-03 0,06076117 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 5,895E-03 0,06050587 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 5,895E-03 0,06025271 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 5,895E-03 0,06000166 ! basic amino acid transport GO:0015802 12 5 0,000 5,895E-03 0,05975269 ! cellular glucose homeostasis GO:0001678 6 5 0,000 5,895E-03 0,05950578 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 5,895E-03 0,0592609 ! actin nucleation GO:0045010 11 5 0,000 5,895E-03 0,05901802 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 5,895E-03 0,05877713 ! depurination GO:0045007 5 5 0,000 5,895E-03 0,0585382 ! depyrimidination GO:0045008 10 5 0,000 5,895E-03 0,05830121 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 5,895E-03 0,05806612 ! regulation of centrosome cycle GO:0046605 7 5 0,000 5,895E-03 0,05783292 ! G2/M transition checkpoint GO:0031576 8 5 0,000 5,895E-03 0,05760159 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 5,895E-03 0,0573721 ! zinc ion homeostasis GO:0055069 9 5 0,000 5,895E-03 0,05714444 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 5,895E-03 0,05691857 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 5,895E-03 0,05669448 ! forebrain morphogenesis GO:0048853 13 5 0,000 5,895E-03 0,05647215 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 5,895E-03 0,05625155 ! activated T cell proliferation GO:0050798 16 5 0,000 5,895E-03 0,05603268 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 5,895E-03 0,0558155 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 5,895E-03 0,05559999 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,895E-03 0,05538615 ! positive regulation of organ growth GO:0046622 6 5 0,000 5,895E-03 0,05517394 ! gamma-delta T cell activation GO:0046629 6 5 0,000 5,895E-03 0,05496335 ! response to arsenic GO:0046685 11 5 0,000 5,895E-03 0,05475436 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 5,895E-03 0,05454696 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 5,895E-03 0,05434112 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 5,895E-03 0,05413683 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 5,895E-03 0,05393407 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 5,895E-03 0,05373283 ! response to mercury ion GO:0046689 8 5 0,000 5,895E-03 0,05353308 ! response to cadmium ion GO:0046686 7 5 0,000 5,895E-03 0,05333481 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 5,895E-03 0,053138 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 5,895E-03 0,05294264 ! bile acid biosynthetic process GO:0006699 7 5 0,000 5,895E-03 0,05274871 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 5,895E-03 0,0525562 ! ganglioside catabolic process GO:0006689 12 5 0,000 5,895E-03 0,05236508 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 5,895E-03 0,05217535 ! decidualization GO:0046697 11 5 0,000 5,895E-03 0,051987 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 5,895E-03 0,05179999 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 5,895E-03 0,05161433 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 5,895E-03 0,05142999 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 5,895E-03 0,05124697 ! embryonic cleavage GO:0040016 6 5 0,000 5,895E-03 0,05106524 ! peroxisome fission GO:0016559 5 5 0,000 5,895E-03 0,0508848 ! histone demethylation GO:0016577 13 5 0,000 5,895E-03 0,05070563 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 5,895E-03 0,05052771 ! mitotic recombination GO:0006312 9 5 0,000 5,895E-03 0,05035104 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 5,895E-03 0,0501756 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 5,895E-03 0,05000138 ! metaphase plate congression GO:0051310 7 5 0,000 5,895E-03 0,04982837 ! regulation of sterol transport GO:0032371 7 5 0,000 5,895E-03 0,04965654 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 5,895E-03 0,0494859 ! enteric nervous system development GO:0048484 8 5 0,000 5,895E-03 0,04931643 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 5,895E-03 0,04914812 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 5,895E-03 0,04898094 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 5,895E-03 0,04881491 ! muscle cell proliferation GO:0033002 12 5 0,000 5,895E-03 0,04864999 ! skeletal muscle regeneration GO:0043403 8 5 0,000 5,895E-03 0,04848619 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 5,895E-03 0,04832348 ! B cell homeostasis GO:0001782 13 5 0,000 5,895E-03 0,04816187 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 5,895E-03 0,04800133 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 5,895E-03 0,04784185 ! metaphase GO:0051323 11 5 0,000 5,895E-03 0,04768344 ! melatonin biosynthetic process GO:0030187 7 5 0,000 5,895E-03 0,04752607 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 5,895E-03 0,04736973 ! cellular response to nutrient GO:0031670 8 5 0,000 5,895E-03 0,04721442 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 5,895E-03 0,04706012 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 5,895E-03 0,04690683 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 5,895E-03 0,04675454 ! regulation of hair follicle development GO:0051797 10 5 0,000 5,895E-03 0,04660323 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 5,895E-03 0,0464529 ! response to redox state GO:0051775 6 5 0,000 5,895E-03 0,04630353 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 5,895E-03 0,04615512 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 5,895E-03 0,04600766 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 5,895E-03 0,04586114 ! brown fat cell differentiation GO:0050873 7 5 0,000 5,895E-03 0,04571555 ! regulation of telomerase activity GO:0051972 7 5 0,000 5,895E-03 0,04557088 ! galactolipid metabolic process GO:0019374 7 5 0,000 5,895E-03 0,04542712 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 5,895E-03 0,04528427 ! porphyrin catabolic process GO:0006787 12 5 0,000 5,895E-03 0,04514231 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 5,895E-03 0,04500124 ! striatum development GO:0021756 14 5 0,000 5,895E-03 0,04486105 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 5,895E-03 0,04472173 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 5,895E-03 0,04458327 ! glial cell migration GO:0008347 10 5 0,000 5,895E-03 0,04444567 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 5,895E-03 0,04430892 ! neural plate morphogenesis GO:0001839 7 5 0,000 5,895E-03 0,044173 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 5,895E-03 0,04403791 ! somatic stem cell maintenance GO:0035019 15 5 0,000 5,895E-03 0,04390365 ! T cell activation during immune response GO:0002286 9 5 0,000 5,895E-03 0,04377021 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 5,895E-03 0,04363757 ! negative regulation of lipase activity GO:0060192 8 5 0,000 5,895E-03 0,04350573 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 5,895E-03 0,04337469 ! neuroprotection GO:0043526 8 5 0,000 5,895E-03 0,04324444 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 5,895E-03 0,04311496 ! regulation of sensory perception GO:0051931 8 5 0,000 5,895E-03 0,04298626 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 5,895E-03 0,04285833 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 5,895E-03 0,04273115 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 5,895E-03 0,04260473 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 5,895E-03 0,04247905 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 5,895E-03 0,04235411 ! sequestering of calcium ion GO:0051208 7 5 0,000 5,895E-03 0,04222991 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 5,895E-03 0,04210643 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 5,895E-03 0,04198367 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 5,895E-03 0,04186162 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 5,895E-03 0,04174028 ! spindle assembly GO:0051225 6 5 0,000 5,895E-03 0,04161965 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 5,895E-03 0,04149971 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 5,895E-03 0,04138045 ! protein palmitoylation GO:0018345 12 5 0,000 5,895E-03 0,04126188 ! drug metabolic process GO:0017144 7 5 0,000 5,895E-03 0,04114399 ! stem cell division GO:0017145 11 5 0,000 5,895E-03 0,04102677 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 5,895E-03 0,04091022 ! organ regeneration GO:0031100 7 5 0,000 5,895E-03 0,04079433 ! carnitine metabolic process GO:0009437 8 5 0,000 5,895E-03 0,04067909 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 5,895E-03 0,0405645 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 7,069E-03 0,04851269 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 7,069E-03 0,0483768 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 7,069E-03 0,04824167 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 7,069E-03 0,04810729 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 7,069E-03 0,04797366 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 7,069E-03 0,04784077 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 7,069E-03 0,04770861 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 7,069E-03 0,04757718 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 7,069E-03 0,04744648 ! response to oxygen radical GO:0000305 11 6 0,000 7,069E-03 0,04731649 ! positive regulation of axon extension GO:0045773 13 6 0,000 7,069E-03 0,04718721 ! myoblast cell fate commitment GO:0048625 18 6 0,000 7,069E-03 0,04705863 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 7,069E-03 0,04693075 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 7,069E-03 0,04680357 ! regulation of interferon-beta production GO:0032648 8 6 0,000 7,069E-03 0,04667707 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 7,069E-03 0,04655126 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 7,069E-03 0,04642612 ! forebrain regionalization GO:0021871 9 6 0,000 7,069E-03 0,04630166 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 7,069E-03 0,04617785 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 7,069E-03 0,04605471 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 7,069E-03 0,04593223 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 7,069E-03 0,04581039 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 7,069E-03 0,0456892 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 7,069E-03 0,04556865 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 7,069E-03 0,04544873 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 7,069E-03 0,04532944 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 7,069E-03 0,04521078 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 7,069E-03 0,04509273 ! malate metabolic process GO:0006108 13 6 0,000 7,069E-03 0,04497531 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 7,069E-03 0,04485849 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 7,069E-03 0,04474227 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 7,069E-03 0,04462666 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 7,069E-03 0,04451164 ! protein refolding GO:0042026 15 6 0,000 7,069E-03 0,04439722 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 7,069E-03 0,04428338 ! opsonization GO:0008228 8 6 0,000 7,069E-03 0,04417012 ! mating behavior GO:0007617 7 6 0,000 7,069E-03 0,04405744 ! erythrocyte maturation GO:0043249 8 6 0,000 7,069E-03 0,04394534 ! embryonic hemopoiesis GO:0035162 16 6 0,000 7,069E-03 0,0438338 ! protein amino acid dealkylation GO:0008214 15 6 0,000 7,069E-03 0,04372283 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 7,069E-03 0,04361242 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 7,069E-03 0,04350256 ! response to interferon-gamma GO:0034341 16 6 0,000 7,069E-03 0,04339326 ! toxin metabolic process GO:0009404 11 6 0,000 7,069E-03 0,0432845 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 7,069E-03 0,04317629 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 7,069E-03 0,04306862 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 7,069E-03 0,04296149 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 7,069E-03 0,04285488 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 7,069E-03 0,04274881 ! cGMP-mediated signaling GO:0019934 14 6 0,000 7,069E-03 0,04264325 ! dorsal spinal cord development GO:0021516 10 6 0,000 7,069E-03 0,04253822 ! activation of MAPKKK activity GO:0000185 12 6 0,000 7,069E-03 0,0424337 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 7,069E-03 0,0423297 ! thymic T cell selection GO:0045061 16 6 0,000 7,069E-03 0,0422262 ! sphingoid catabolic process GO:0046521 8 6 0,000 7,069E-03 0,04212321 ! protein lipoylation GO:0009249 10 6 0,000 7,069E-03 0,04202072 ! transepithelial chloride transport GO:0030321 12 6 0,000 7,069E-03 0,04191873 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 7,069E-03 0,04181723 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 7,069E-03 0,04171623 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 7,069E-03 0,0416157 ! glutamate catabolic process GO:0006538 12 6 0,000 7,069E-03 0,04151567 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 7,069E-03 0,04141611 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 7,069E-03 0,04131703 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 7,069E-03 0,04121842 ! hyperosmotic response GO:0006972 10 6 0,000 7,069E-03 0,04112028 ! L-serine biosynthetic process GO:0006564 7 6 0,000 7,069E-03 0,04102261 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 7,069E-03 0,0409254 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 7,069E-03 0,04082865 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 7,069E-03 0,04073235 ! urea metabolic process GO:0019627 7 6 0,000 7,069E-03 0,04063651 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 7,069E-03 0,04054112 ! neutrophil activation GO:0042119 7 6 0,000 7,069E-03 0,04044618 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 7,069E-03 0,04035168 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 7,069E-03 0,04025762 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 7,069E-03 0,04016399 ! paraxial mesoderm development GO:0048339 16 6 0,000 7,069E-03 0,04007081 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 7,069E-03 0,03997805 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 7,069E-03 0,03988572 ! neuron apoptosis GO:0051402 15 6 0,000 7,069E-03 0,03979382 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 7,069E-03 0,03970234 ! T cell mediated immunity GO:0002456 17 6 0,000 7,069E-03 0,03961128 ! negative regulation of platelet activation GO:0010544 9 6 0,000 7,069E-03 0,03952063 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 7,069E-03 0,03943041 ! carnitine transport GO:0015879 10 6 0,000 7,069E-03 0,03934059 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,069E-03 0,03925118 ! positive regulation of exocytosis GO:0045921 11 6 0,000 7,069E-03 0,03916217 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 7,069E-03 0,03907357 ! early endosome to late endosome transport GO:0045022 16 6 0,000 7,069E-03 0,03898537 ! 5S class rRNA transcription GO:0042791 13 6 0,000 7,069E-03 0,03889756 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 7,069E-03 0,03881015 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 7,069E-03 0,03872313 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 7,069E-03 0,0386365 ! sodium ion homeostasis GO:0055078 12 6 0,000 7,069E-03 0,03855026 ! establishment of spindle localization GO:0051293 16 6 0,000 7,069E-03 0,0384644 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 7,069E-03 0,03837893 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 7,069E-03 0,03829383 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 7,069E-03 0,03820911 ! response to UV-C GO:0010225 14 6 0,000 7,069E-03 0,03812476 ! astrocyte development GO:0014002 16 6 0,000 7,069E-03 0,03804079 ! protein targeting to lysosome GO:0006622 12 6 0,000 7,069E-03 0,03795718 ! purine base biosynthetic process GO:0009113 17 6 0,000 7,069E-03 0,03787394 ! interaction with symbiont GO:0051702 14 6 0,000 7,069E-03 0,03779107 ! regulation of dendrite development GO:0050773 16 6 0,000 7,069E-03 0,03770855 ! peptidyl-arginine modification GO:0018195 13 6 0,000 7,069E-03 0,0376264 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 7,069E-03 0,0375446 ! response to copper ion GO:0046688 10 6 0,000 7,069E-03 0,03746316 ! response to exogenous dsRNA GO:0043330 13 6 0,000 7,069E-03 0,03738207 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 7,069E-03 0,03730133 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,069E-03 0,03722094 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 7,069E-03 0,0371409 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 7,069E-03 0,0370612 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 7,069E-03 0,03698184 ! regulation of dopamine secretion GO:0014059 14 6 0,000 7,069E-03 0,03690282 ! nucleoside catabolic process GO:0009164 10 6 0,000 7,069E-03 0,03682413 ! hair follicle maturation GO:0048820 8 6 0,000 7,069E-03 0,03674578 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 7,069E-03 0,03666777 ! Schwann cell development GO:0014044 15 6 0,000 7,069E-03 0,03659008 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 7,069E-03 0,03651272 ! response to pheromone GO:0019236 6 6 0,000 7,069E-03 0,03643569 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 7,069E-03 0,03635898 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 7,069E-03 0,0362826 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 7,069E-03 0,03620654 ! base conversion or substitution editing GO:0016553 6 6 0,000 7,069E-03 0,03613079 ! subpallium development GO:0021544 15 6 0,000 7,069E-03 0,03605536 ! neural tube patterning GO:0021532 8 6 0,000 7,069E-03 0,03598024 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 7,069E-03 0,03590544 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 7,069E-03 0,03583095 ! maintenance of organ identity GO:0048496 9 6 0,000 7,069E-03 0,03575676 ! G2 phase GO:0051319 16 6 0,000 7,069E-03 0,03568289 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 7,069E-03 0,03560931 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 7,069E-03 0,03553604 ! oxygen homeostasis GO:0032364 10 6 0,000 7,069E-03 0,03546307 ! establishment of planar polarity GO:0001736 7 6 0,000 7,069E-03 0,0353904 ! regulation of mast cell activation GO:0033003 13 6 0,000 7,069E-03 0,03531803 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 7,069E-03 0,03524595 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 7,069E-03 0,03517417 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 7,069E-03 0,03510268 ! receptor internalization GO:0031623 11 6 0,000 7,069E-03 0,03503148 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 7,069E-03 0,03496056 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 7,069E-03 0,03488993 ! neutrophil homeostasis GO:0001780 11 6 0,000 7,069E-03 0,03481959 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 7,069E-03 0,03474953 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 7,069E-03 0,03467975 ! protein deubiquitination GO:0016579 16 6 0,000 7,069E-03 0,03461026 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 7,069E-03 0,03454103 ! protein destabilization GO:0031648 9 6 0,000 7,069E-03 0,03447209 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 7,069E-03 0,03440342 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 7,069E-03 0,03433502 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 7,069E-03 0,0342669 ! regulation of viral transcription GO:0046782 11 6 0,000 7,069E-03 0,03419904 ! progesterone metabolic process GO:0042448 12 6 0,000 7,069E-03 0,03413146 ! negative regulation of axon extension GO:0030517 24 6 0,000 7,069E-03 0,03406414 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 7,069E-03 0,03399708 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 7,069E-03 0,03393029 ! triglyceride catabolic process GO:0019433 10 6 0,000 7,069E-03 0,03386376 ! determination of adult lifespan GO:0008340 17 6 0,000 7,069E-03 0,03379749 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 7,069E-03 0,03373148 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 7,069E-03 0,03366573 ! neural plate development GO:0001840 9 6 0,000 7,069E-03 0,03360023 ! catecholamine transport GO:0051937 9 6 0,000 7,069E-03 0,03353499 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 7,069E-03 0,03347 ! sensory cilium assembly GO:0035058 10 6 0,000 7,069E-03 0,03340526 ! organ or tissue specific immune response GO:0002251 8 6 0,000 7,069E-03 0,03334077 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 7,069E-03 0,03327653 ! maternal placenta development GO:0001893 12 6 0,000 7,069E-03 0,03321253 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 7,069E-03 0,03314879 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 7,069E-03 0,03308528 ! negative regulation of B cell activation GO:0050869 14 6 0,000 7,069E-03 0,03302202 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 7,069E-03 0,032959 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 7,069E-03 0,03289622 ! positive regulation of coagulation GO:0050820 13 6 0,000 7,069E-03 0,03283368 ! cellular anion homeostasis GO:0030002 11 6 0,000 7,069E-03 0,03277138 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 8,243E-03 0,03813887 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 8,243E-03 0,03806678 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 8,243E-03 0,03799495 ! behavioral response to cocaine GO:0048148 14 7 0,000 8,243E-03 0,0379234 ! regulation of helicase activity GO:0051095 16 7 0,000 8,243E-03 0,03785212 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 8,243E-03 0,0377811 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 8,243E-03 0,03771035 ! sleep GO:0030431 16 7 0,000 8,243E-03 0,03763986 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 8,243E-03 0,03756964 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 8,243E-03 0,03749968 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 8,243E-03 0,03742997 ! prostate gland development GO:0030850 14 7 0,000 8,243E-03 0,03736053 ! nucleotide-sugar transport GO:0015780 11 7 0,000 8,243E-03 0,03729134 ! synaptonemal complex assembly GO:0007130 10 7 0,000 8,243E-03 0,03722241 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 8,243E-03 0,03715374 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 8,243E-03 0,03708531 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 8,243E-03 0,03701714 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 8,243E-03 0,03694922 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 8,243E-03 0,03688155 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 8,243E-03 0,03681412 ! SMAD protein complex assembly GO:0007183 13 7 0,000 8,243E-03 0,03674695 ! glycolipid transport GO:0046836 11 7 0,000 8,243E-03 0,03668001 ! protein amino acid sulfation GO:0006477 10 7 0,000 8,243E-03 0,03661332 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 8,243E-03 0,03654687 ! neuron adhesion GO:0007158 14 7 0,000 8,243E-03 0,03648066 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 8,243E-03 0,03641469 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 8,243E-03 0,03634896 ! establishment of tissue polarity GO:0007164 8 7 0,000 8,243E-03 0,03628347 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 8,243E-03 0,03621821 ! mRNA stabilization GO:0048255 18 7 0,000 8,243E-03 0,03615319 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 8,243E-03 0,0360884 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 8,243E-03 0,03602384 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 8,243E-03 0,03595951 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 8,243E-03 0,03589541 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 8,243E-03 0,03583154 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 8,243E-03 0,0357679 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 8,243E-03 0,03570448 ! lipoprotein transport GO:0042953 14 7 0,000 8,243E-03 0,03564128 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 8,243E-03 0,03557831 ! rhythmic behavior GO:0007622 17 7 0,000 8,243E-03 0,03551557 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 8,243E-03 0,03545304 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 8,243E-03 0,03539073 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 8,243E-03 0,03532864 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 8,243E-03 0,03526677 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 8,243E-03 0,03520512 ! regulation of odontogenesis GO:0042481 14 7 0,000 8,243E-03 0,03514368 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 8,243E-03 0,03508245 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 8,243E-03 0,03502144 ! mechanosensory behavior GO:0007638 16 7 0,000 8,243E-03 0,03496064 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 8,243E-03 0,03490004 ! positive regulation of isotype switching GO:0045830 17 7 0,000 8,243E-03 0,03483966 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 8,243E-03 0,03477949 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 8,243E-03 0,03471953 ! protein-cofactor linkage GO:0018065 13 7 0,000 8,243E-03 0,03465977 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 8,243E-03 0,03460022 ! spinal cord patterning GO:0021511 14 7 0,000 8,243E-03 0,03454087 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 8,243E-03 0,03448172 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 8,243E-03 0,03442278 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 8,243E-03 0,03436404 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 8,243E-03 0,0343055 ! adrenal gland development GO:0030325 17 7 0,000 8,243E-03 0,03424715 ! cysteine metabolic process GO:0006534 13 7 0,000 8,243E-03 0,03418901 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 8,243E-03 0,03413106 ! ovulation GO:0030728 10 7 0,000 8,243E-03 0,03407331 ! adenohypophysis development GO:0021984 11 7 0,000 8,243E-03 0,03401575 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 8,243E-03 0,03395839 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 8,243E-03 0,03390122 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 8,243E-03 0,03384425 ! microtubule nucleation GO:0007020 21 7 0,000 8,243E-03 0,03378746 ! proline biosynthetic process GO:0006561 10 7 0,000 8,243E-03 0,03373086 ! tryptophan metabolic process GO:0006568 11 7 0,000 8,243E-03 0,03367446 ! thyroid hormone generation GO:0006590 13 7 0,000 8,243E-03 0,03361824 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 8,243E-03 0,03356221 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 8,243E-03 0,03350637 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 8,243E-03 0,03345071 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 8,243E-03 0,03339523 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 8,243E-03 0,03333994 ! galactose metabolic process GO:0006012 13 7 0,000 8,243E-03 0,03328484 ! vesicle fusion GO:0006906 20 7 0,000 8,243E-03 0,03322991 ! response to dietary excess GO:0002021 8 7 0,000 8,243E-03 0,03317517 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 8,243E-03 0,0331206 ! intracellular pH reduction GO:0051452 13 7 0,000 8,243E-03 0,03306622 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 8,243E-03 0,03301201 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 8,243E-03 0,03295798 ! organ growth GO:0035265 15 7 0,000 8,243E-03 0,03290413 ! nucleoside transport GO:0015858 11 7 0,000 8,243E-03 0,03285045 ! nucleoside salvage GO:0043174 11 7 0,000 8,243E-03 0,03279695 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 8,243E-03 0,03274362 ! male sex determination GO:0030238 15 7 0,000 8,243E-03 0,03269046 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 8,243E-03 0,03263748 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 8,243E-03 0,03258467 ! parturition GO:0007567 16 7 0,000 8,243E-03 0,03253203 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 8,243E-03 0,03247956 ! rRNA modification GO:0000154 14 7 0,000 8,243E-03 0,03242726 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 8,243E-03 0,03237512 ! spindle checkpoint GO:0031577 16 7 0,000 8,243E-03 0,03232316 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 8,243E-03 0,03227136 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 8,243E-03 0,03221972 ! monocyte differentiation GO:0030224 16 7 0,000 8,243E-03 0,03216825 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 8,243E-03 0,03211695 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 8,243E-03 0,03206581 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 8,243E-03 0,03201483 ! hyaluronan metabolic process GO:0030212 9 7 0,000 8,243E-03 0,03196401 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 8,243E-03 0,03191335 ! anterograde axon cargo transport GO:0008089 18 7 0,000 8,243E-03 0,03186286 ! fibrinolysis GO:0042730 11 7 0,000 8,243E-03 0,03181252 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 8,243E-03 0,03176234 ! skeletal muscle contraction GO:0003009 8 7 0,000 8,243E-03 0,03171232 ! eating behavior GO:0042755 8 7 0,000 8,243E-03 0,03166246 ! B cell lineage commitment GO:0002326 21 7 0,000 8,243E-03 0,03161276 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 8,243E-03 0,03156321 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 8,243E-03 0,03151381 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 8,243E-03 0,03146457 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 8,243E-03 0,03141548 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 8,243E-03 0,03136655 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 8,243E-03 0,03131777 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 8,243E-03 0,03126914 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 8,243E-03 0,03122066 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 8,243E-03 0,03117233 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 8,243E-03 0,03112415 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 8,243E-03 0,03107612 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 8,243E-03 0,03102824 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 8,243E-03 0,0309805 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 8,243E-03 0,03093291 ! histone ubiquitination GO:0016574 9 7 0,000 8,243E-03 0,03088547 ! regulation of meiosis GO:0040020 12 7 0,000 8,243E-03 0,03083817 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 8,243E-03 0,03079102 ! T cell lineage commitment GO:0002360 16 7 0,000 8,243E-03 0,03074401 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 8,243E-03 0,03069714 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 8,243E-03 0,03065042 ! membrane to membrane docking GO:0022614 14 7 0,000 8,243E-03 0,03060384 ! transcription termination GO:0006353 14 7 0,000 8,243E-03 0,0305574 ! coenzyme A metabolic process GO:0015936 12 7 0,000 8,243E-03 0,0305111 ! anaphase GO:0051322 18 7 0,000 8,243E-03 0,03046494 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 8,243E-03 0,03041892 ! axonal fasciculation GO:0007413 19 7 0,000 8,243E-03 0,03037304 ! negative regulation of nuclear division GO:0051784 15 7 0,000 8,243E-03 0,0303273 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 8,243E-03 0,03028169 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 8,243E-03 0,03023623 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 8,243E-03 0,03019089 ! diuresis GO:0030146 12 7 0,000 8,243E-03 0,0301457 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 8,243E-03 0,03010064 ! thiamin metabolic process GO:0006772 7 7 0,000 8,243E-03 0,03005571 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 8,243E-03 0,03001092 ! antibiotic transport GO:0042891 9 7 0,000 8,243E-03 0,02996626 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 8,243E-03 0,02992173 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 8,243E-03 0,02987734 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 8,243E-03 0,02983308 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 8,243E-03 0,02978894 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 8,243E-03 0,02974494 ! melanin biosynthetic process GO:0042438 10 7 0,000 8,243E-03 0,02970107 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 8,243E-03 0,02965733 ! dopamine biosynthetic process GO:0042416 18 7 0,000 8,243E-03 0,02961371 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 8,243E-03 0,02957023 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 8,243E-03 0,02952687 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 8,243E-03 0,02948364 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 8,243E-03 0,02944053 ! endosome to lysosome transport GO:0008333 12 7 0,000 8,243E-03 0,02939756 ! protein modification by small protein removal GO:0070646 19 7 0,000 8,243E-03 0,0293547 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 8,243E-03 0,02931197 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 8,243E-03 0,02926937 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 8,243E-03 0,02922689 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 8,243E-03 0,02918453 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 8,243E-03 0,0291423 ! muscle adaptation GO:0043500 13 7 0,000 8,243E-03 0,02910018 ! embryonic heart tube development GO:0035050 14 7 0,000 8,243E-03 0,02905819 ! retina homeostasis GO:0001895 12 7 0,000 8,243E-03 0,02901632 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 8,243E-03 0,02897457 ! protein amino acid prenylation GO:0018346 19 7 0,000 8,243E-03 0,02893294 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 8,243E-03 0,02889143 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 8,243E-03 0,02885004 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 9,415E-03 0,03290533 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 9,415E-03 0,03285832 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 9,415E-03 0,03281145 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 9,415E-03 0,03276471 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 9,415E-03 0,0327181 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 9,415E-03 0,03267163 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 9,415E-03 0,03262529 ! male meiosis GO:0007140 9 8 0,000 9,415E-03 0,03257907 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 9,415E-03 0,03253299 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 9,415E-03 0,03248704 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 9,415E-03 0,03244122 ! meiotic prophase I GO:0007128 14 8 0,000 9,415E-03 0,03239553 ! response to zinc ion GO:0010043 12 8 0,000 9,415E-03 0,03234997 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 9,415E-03 0,03230453 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 9,415E-03 0,03225922 ! oligopeptide transport GO:0006857 16 8 0,000 9,415E-03 0,03221404 ! actin-myosin filament sliding GO:0033275 13 8 0,000 9,415E-03 0,03216899 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 9,415E-03 0,03212406 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 9,415E-03 0,03207926 ! signal peptide processing GO:0006465 12 8 0,000 9,415E-03 0,03203458 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 9,415E-03 0,03199002 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 9,415E-03 0,03194559 ! macrophage chemotaxis GO:0048246 12 8 0,000 9,415E-03 0,03190129 ! succinate metabolic process GO:0006105 17 8 0,000 9,415E-03 0,0318571 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 9,415E-03 0,03181304 ! membrane hyperpolarization GO:0060081 11 8 0,000 9,415E-03 0,0317691 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 9,415E-03 0,03172528 ! estrogen metabolic process GO:0008210 17 8 0,000 9,415E-03 0,03168158 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 9,415E-03 0,031638 ! T-helper 1 type immune response GO:0042088 12 8 0,000 9,415E-03 0,03159454 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 9,415E-03 0,0315512 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 9,415E-03 0,03150798 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 9,415E-03 0,03146488 ! reflex GO:0060004 17 8 0,000 9,415E-03 0,03142189 ! endothelial cell differentiation GO:0045446 17 8 0,000 9,415E-03 0,03137903 ! glycerolipid catabolic process GO:0046503 14 8 0,000 9,415E-03 0,03133628 ! hemoglobin metabolic process GO:0020027 14 8 0,000 9,415E-03 0,03129364 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 9,415E-03 0,03125112 ! pigment granule organization GO:0048753 17 8 0,000 9,415E-03 0,03120872 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 9,415E-03 0,03116643 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 9,415E-03 0,03112426 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 9,415E-03 0,0310822 ! astrocyte differentiation GO:0048708 19 8 0,000 9,415E-03 0,03104025 ! histidine catabolic process GO:0006548 10 8 0,000 9,415E-03 0,03099842 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 9,415E-03 0,0309567 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 9,415E-03 0,03091509 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 9,415E-03 0,03087359 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 9,415E-03 0,03083221 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 9,415E-03 0,03079093 ! regulation of pigmentation during development GO:0048070 25 8 0,000 9,415E-03 0,03074977 ! melanin metabolic process GO:0006582 17 8 0,000 9,415E-03 0,03070871 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 9,415E-03 0,03066777 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 9,415E-03 0,03062693 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 9,415E-03 0,03058621 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 9,415E-03 0,03054559 ! macrophage activation GO:0042116 13 8 0,000 9,415E-03 0,03050508 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 9,415E-03 0,03046467 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 9,415E-03 0,03042437 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 9,415E-03 0,03038418 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 9,415E-03 0,0303441 ! purine salvage GO:0043101 12 8 0,000 9,415E-03 0,03030412 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 9,415E-03 0,03026425 ! regulation of vascular permeability GO:0043114 12 8 0,000 9,415E-03 0,03022448 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 9,415E-03 0,03018481 ! osteoblast development GO:0002076 17 8 0,000 9,415E-03 0,03014525 ! positive regulation of vasodilation GO:0045909 14 8 0,000 9,415E-03 0,03010579 ! negative regulation of translational initiation GO:0045947 12 8 0,000 9,415E-03 0,03006644 ! Schwann cell differentiation GO:0014037 21 8 0,000 9,415E-03 0,03002719 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 9,415E-03 0,02998804 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 9,415E-03 0,02994899 ! response to UV-B GO:0010224 17 8 0,000 9,415E-03 0,02991005 ! protein targeting to vacuole GO:0006623 14 8 0,000 9,415E-03 0,0298712 ! protein retention in ER lumen GO:0006621 14 8 0,000 9,415E-03 0,02983246 ! intermediate filament organization GO:0045109 12 8 0,000 9,415E-03 0,02979382 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 9,415E-03 0,02975527 ! cellular extravasation GO:0045123 13 8 0,000 9,415E-03 0,02971683 ! cardiac muscle cell development GO:0055013 14 8 0,000 9,415E-03 0,02967849 ! response to antibiotic GO:0046677 11 8 0,000 9,415E-03 0,02964024 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 9,415E-03 0,02960209 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 9,415E-03 0,02956404 ! DNA topological change GO:0006265 12 8 0,000 9,415E-03 0,02952609 ! response to tropane GO:0014073 15 8 0,000 9,415E-03 0,02948824 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 9,415E-03 0,02945048 ! melanosome transport GO:0032402 13 8 0,000 9,415E-03 0,02941282 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 9,415E-03 0,02937526 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 9,415E-03 0,02933779 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 9,415E-03 0,02930042 ! mast cell activation GO:0045576 14 8 0,000 9,415E-03 0,02926314 ! multicellular organismal aging GO:0010259 20 8 0,000 9,415E-03 0,02922596 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 9,415E-03 0,02918887 ! gas homeostasis GO:0033483 14 8 0,000 9,415E-03 0,02915187 ! dendrite morphogenesis GO:0048813 14 8 0,000 9,415E-03 0,02911497 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 9,415E-03 0,02907816 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 9,415E-03 0,02904145 ! nucleosome disassembly GO:0006337 14 8 0,000 9,415E-03 0,02900483 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 9,415E-03 0,0289683 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 9,415E-03 0,02893186 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 9,415E-03 0,02889551 ! establishment of chromosome localization GO:0051303 14 8 0,000 9,415E-03 0,02885926 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 9,415E-03 0,02882309 ! intracellular lipid transport GO:0032365 16 8 0,000 9,415E-03 0,02878702 ! response to tumor cell GO:0002347 16 8 0,000 9,415E-03 0,02875103 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 9,415E-03 0,02871514 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 9,415E-03 0,02867934 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 9,415E-03 0,02864362 ! positive regulation of epidermis development GO:0045684 13 8 0,000 9,415E-03 0,02860799 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 9,415E-03 0,02857246 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 9,415E-03 0,02853701 ! hormone catabolic process GO:0042447 17 8 0,000 9,415E-03 0,02850164 ! glycolipid catabolic process GO:0019377 16 8 0,000 9,415E-03 0,02846637 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 9,415E-03 0,02843118 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 9,415E-03 0,02839608 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 9,415E-03 0,02836107 ! positive regulation of glucose import GO:0046326 8 8 0,000 9,415E-03 0,02832614 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 9,415E-03 0,0282913 ! adult feeding behavior GO:0008343 10 8 0,000 9,415E-03 0,02825654 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 9,415E-03 0,02822187 ! ATP catabolic process GO:0006200 11 8 0,000 9,415E-03 0,02818729 ! blastocyst growth GO:0001832 19 8 0,000 9,415E-03 0,02815279 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 9,415E-03 0,02811837 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 9,415E-03 0,02808404 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 9,415E-03 0,02804979 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 9,415E-03 0,02801562 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 9,415E-03 0,02798154 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 9,415E-03 0,02794754 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 9,415E-03 0,02791362 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 9,415E-03 0,02787979 ! amino sugar catabolic process GO:0046348 11 8 0,000 9,415E-03 0,02784604 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 9,415E-03 0,02781237 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 9,415E-03 0,02777878 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 9,415E-03 0,02774527 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 9,415E-03 0,02771184 ! behavioral response to nicotine GO:0035095 12 8 0,000 9,415E-03 0,02767849 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 9,415E-03 0,02764522 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 9,415E-03 0,02761204 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 9,415E-03 0,02757893 ! NAD biosynthetic process GO:0009435 17 8 0,000 9,415E-03 0,0275459 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 9,415E-03 0,02751295 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 9,415E-03 0,02748008 ! axon extension GO:0048675 16 9 0,000 0,01058577 0,03086041 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01058577 0,03082363 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01058577 0,03078693 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,01058577 0,03075033 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01058577 0,03071381 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01058577 0,03067737 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01058577 0,03064102 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01058577 0,03060476 ! reproductive behavior GO:0019098 22 9 0,000 0,01058577 0,03056859 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01058577 0,0305325 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01058577 0,03049649 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01058577 0,03046057 ! UTP metabolic process GO:0046051 10 9 0,000 0,01058577 0,03042473 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01058577 0,03038898 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01058577 0,03035331 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01058577 0,03031773 ! artery development GO:0060840 25 9 0,000 0,01058577 0,03028223 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01058577 0,03024681 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01058577 0,03021148 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01058577 0,03017622 ! equilibrioception GO:0050957 20 9 0,000 0,01058577 0,03014105 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01058577 0,03010596 ! chemosensory behavior GO:0007635 21 9 0,000 0,01058577 0,03007096 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01058577 0,03003603 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01058577 0,03000119 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01058577 0,02996642 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01058577 0,02993174 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01058577 0,02989714 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01058577 0,02986261 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01058577 0,02982817 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01058577 0,02979381 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01058577 0,02975952 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01058577 0,02972531 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01058577 0,02969119 ! protein targeting to ER GO:0045047 25 9 0,000 0,01058577 0,02965714 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01058577 0,02962317 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01058577 0,02958927 ! T cell selection GO:0045058 27 9 0,000 0,01058577 0,02955546 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,01058577 0,02952172 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01058577 0,02948805 ! glycine catabolic process GO:0006546 15 9 0,000 0,01058577 0,02945447 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01058577 0,02942096 ! endosome organization GO:0007032 20 9 0,000 0,01058577 0,02938753 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01058577 0,02935417 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01058577 0,02932089 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01058577 0,02928768 ! mannose metabolic process GO:0006013 13 9 0,000 0,01058577 0,02925455 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01058577 0,0292215 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01058577 0,02918851 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01058577 0,02915561 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01058577 0,02912277 ! receptor clustering GO:0043113 20 9 0,000 0,01058577 0,02909002 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01058577 0,02905733 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01058577 0,02902472 ! retinol metabolic process GO:0042572 20 9 0,000 0,01058577 0,02899218 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01058577 0,02895971 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01058577 0,02892732 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01058577 0,028895 ! macrophage differentiation GO:0030225 15 9 0,000 0,01058577 0,02886275 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01058577 0,02883057 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01058577 0,02879847 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01058577 0,02876643 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01058577 0,02873447 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01058577 0,02870258 ! response to amine stimulus GO:0014075 13 9 0,000 0,01058577 0,02867076 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01058577 0,02863901 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01058577 0,02860733 ! erythrocyte development GO:0048821 17 9 0,000 0,01058577 0,02857572 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01058577 0,02854418 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01058577 0,02851271 ! renal water homeostasis GO:0003091 15 9 0,000 0,01058577 0,0284813 ! postreplication repair GO:0006301 25 9 0,000 0,01058577 0,02844997 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01058577 0,02841871 ! icosanoid secretion GO:0032309 15 9 0,000 0,01058577 0,02838751 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01058577 0,02835639 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01058577 0,02832533 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01058577 0,02829434 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01058577 0,02826341 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01058577 0,02823256 ! sterol catabolic process GO:0016127 14 9 0,000 0,01058577 0,02820177 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01058577 0,02817105 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01058577 0,0281404 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01058577 0,02810981 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01058577 0,02807929 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01058577 0,02804883 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01058577 0,02801844 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01058577 0,02798812 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01058577 0,02795786 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01058577 0,02792767 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01058577 0,02789754 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01058577 0,02786748 ! purine base metabolic process GO:0006144 25 9 0,000 0,01058577 0,02783749 ! pigment granule transport GO:0051904 17 9 0,000 0,01058577 0,02780755 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01058577 0,02777768 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01058577 0,02774788 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01058577 0,02771814 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01058577 0,02768846 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01058577 0,02765885 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01058577 0,0276293 ! mitochondrion localization GO:0051646 18 9 0,000 0,01058577 0,02759981 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01175519 0,03061612 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01175519 0,03058352 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01175519 0,03055098 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01175519 0,03051851 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01175519 0,03048612 ! associative learning GO:0008306 21 10 0,000 0,01175519 0,03045379 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01175519 0,03042153 ! phosphate transport GO:0006817 24 10 0,000 0,01175519 0,03038933 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01175519 0,03035721 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01175519 0,03032515 ! CTP metabolic process GO:0046036 11 10 0,000 0,01175519 0,03029317 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01175519 0,03026124 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01175519 0,03022939 ! GTP metabolic process GO:0046039 11 10 0,000 0,01175519 0,0301976 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01175519 0,03016588 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01175519 0,03013423 ! social behavior GO:0035176 29 10 0,000 0,01175519 0,03010264 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01175519 0,03007112 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01175519 0,03003967 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01175519 0,03000828 ! androgen metabolic process GO:0008209 17 10 0,000 0,01175519 0,02997695 ! phospholipid efflux GO:0033700 19 10 0,000 0,01175519 0,02994569 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01175519 0,0299145 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01175519 0,02988337 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01175519 0,02985231 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01175519 0,02982131 ! lung alveolus development GO:0048286 26 10 0,000 0,01175519 0,02979037 ! pathogenesis GO:0009405 17 10 0,000 0,01175519 0,0297595 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01175519 0,0297287 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01175519 0,02969795 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01175519 0,02966727 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01175519 0,02963666 ! endoderm development GO:0007492 18 10 0,000 0,01175519 0,0296061 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01175519 0,02957561 ! arginine catabolic process GO:0006527 17 10 0,000 0,01175519 0,02954519 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01175519 0,02951482 ! proline metabolic process GO:0006560 13 10 0,000 0,01175519 0,02948452 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01175519 0,02945428 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01175519 0,0294241 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01175519 0,02939398 ! V(D)J recombination GO:0033151 34 10 0,000 0,01175519 0,02936393 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01175519 0,02933393 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01175519 0,029304 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01175519 0,02927413 ! B cell proliferation GO:0042100 19 10 0,000 0,01175519 0,02924432 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01175519 0,02921457 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01175519 0,02918488 ! multicellular organism growth GO:0035264 19 10 0,000 0,01175519 0,02915525 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01175519 0,02912568 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01175519 0,02909617 ! ruffle organization GO:0031529 17 10 0,000 0,01175519 0,02906672 ! epithelial cell development GO:0002064 21 10 0,000 0,01175519 0,02903733 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01175519 0,029008 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01175519 0,02897873 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01175519 0,02894952 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01175519 0,02892036 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01175519 0,02889127 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01175519 0,02886223 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01175519 0,02883325 ! motor axon guidance GO:0008045 22 10 0,000 0,01175519 0,02880433 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01175519 0,02877547 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01175519 0,02874667 ! protein heterooligomerization GO:0051291 17 10 0,000 0,01175519 0,02871792 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01175519 0,02868923 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01175519 0,0286606 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01175519 0,02863202 ! segment specification GO:0007379 15 10 0,000 0,01175519 0,02860351 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01175519 0,02857505 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01175519 0,02854664 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01175519 0,02851829 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01175519 0,02849 ! response to dsRNA GO:0043331 23 10 0,000 0,01175519 0,02846177 ! DNA ligation GO:0006266 18 10 0,000 0,01175519 0,02843359 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01175519 0,02840546 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01175519 0,02837739 ! melanosome localization GO:0032400 16 10 0,000 0,01175519 0,02834938 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01175519 0,02832142 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01175519 0,02829352 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01175519 0,02826567 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01175519 0,02823788 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01175519 0,02821014 ! induction of an organ GO:0001759 17 10 0,000 0,01175519 0,02818245 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01175519 0,02815482 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01175519 0,02812725 ! protein sumoylation GO:0016925 17 10 0,000 0,01175519 0,02809973 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01175519 0,02807226 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01175519 0,02804484 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01175519 0,02801748 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01175519 0,02799018 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01175519 0,02796292 ! salivary gland development GO:0007431 28 10 0,000 0,01175519 0,02793572 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01175519 0,02790857 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01175519 0,02788148 ! midbrain development GO:0030901 14 10 0,000 0,01175519 0,02785443 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01175519 0,02782744 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01175519 0,0278005 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01175519 0,02777362 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01175519 0,02774678 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01175519 0,02772 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01175519 0,02769327 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01175519 0,02766659 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01175519 0,02763996 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01175519 0,02761339 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,01175519 0,02758686 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,01175519 0,02756038 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01175519 0,02753396 ! blastocyst formation GO:0001825 18 10 0,000 0,01175519 0,02750759 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01175519 0,02748126 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01175519 0,02745499 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01175519 0,02742877 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01175519 0,0274026 ! response to nicotine GO:0035094 20 10 0,000 0,01175519 0,02737647 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01175519 0,0273504 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01175519 0,02732438 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01292326 0,03001095 ! respiratory burst GO:0045730 17 11 0,000 0,01292326 0,02998245 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01292326 0,02995401 ! neuron fate specification GO:0048665 18 11 0,000 0,01292326 0,02992561 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01292326 0,02989727 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01292326 0,02986899 ! thyroid gland development GO:0030878 26 11 0,000 0,01292326 0,02984076 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,01292326 0,02981258 ! synapsis GO:0007129 14 11 0,000 0,01292326 0,02978445 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01292326 0,02975638 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,01292326 0,02972836 ! response to pain GO:0048265 27 11 0,000 0,01292326 0,0297004 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01292326 0,02967248 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,01292326 0,02964462 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01292326 0,02961681 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01292326 0,02958906 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01292326 0,02956135 ! bone resorption GO:0045453 16 11 0,000 0,01292326 0,0295337 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01292326 0,0295061 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,01292326 0,02947854 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01292326 0,02945105 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01292326 0,0294236 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01292326 0,0293962 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01292326 0,02936886 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01292326 0,02934156 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01292326 0,02931432 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01292326 0,02928713 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01292326 0,02925998 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01292326 0,02923289 ! UV protection GO:0009650 20 11 0,000 0,01292326 0,02920585 ! adult heart development GO:0007512 16 11 0,000 0,01292326 0,02917886 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01292326 0,02915191 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01292326 0,02912502 ! macroautophagy GO:0016236 19 11 0,000 0,01292326 0,02909818 ! temperature homeostasis GO:0001659 18 11 0,000 0,01292326 0,02907138 ! behavioral fear response GO:0001662 27 11 0,000 0,01292326 0,02904464 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01292326 0,02901794 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01292326 0,0289913 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01292326 0,0289647 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01292326 0,02893815 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01292326 0,02891165 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01292326 0,0288852 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01292326 0,02885879 ! regulation of organ growth GO:0046620 14 11 0,000 0,01292326 0,02883244 ! pigment granule localization GO:0051875 20 11 0,000 0,01292326 0,02880613 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01292326 0,02877987 ! vasoconstriction GO:0042310 20 11 0,000 0,01292326 0,02875366 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01292326 0,0287275 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01292326 0,02870138 ! embryonic axis specification GO:0000578 19 11 0,000 0,01292326 0,02867531 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01292326 0,02864929 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01292326 0,02862332 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,01292326 0,02859739 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01292326 0,02857151 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01292326 0,02854568 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01292326 0,02851989 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01292326 0,02849415 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01292326 0,02846846 ! prophase GO:0051324 17 11 0,000 0,01292326 0,02844281 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01292326 0,02841721 ! nucleosome positioning GO:0016584 15 11 0,000 0,01292326 0,02839166 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01292326 0,02836615 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01292326 0,02834068 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01292326 0,02831527 ! apical protein localization GO:0045176 18 11 0,000 0,01292326 0,02828989 ! acid secretion GO:0046717 20 11 0,000 0,01292326 0,02826457 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01292326 0,02823929 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01292326 0,02821405 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01292326 0,02818886 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01292326 0,02816371 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01292326 0,02813861 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01292326 0,02811355 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01292326 0,02808854 ! cholesterol efflux GO:0033344 21 11 0,000 0,01292326 0,02806357 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01292326 0,02803865 ! oocyte development GO:0048599 20 11 0,000 0,01292326 0,02801377 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01292326 0,02798894 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01292326 0,02796415 ! embryonic gut development GO:0048566 19 11 0,000 0,01292326 0,0279394 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01292326 0,0279147 ! activation of innate immune response GO:0002218 16 11 0,000 0,01292326 0,02789004 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,01292326 0,02786542 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01292326 0,02784085 ! lysogeny GO:0030069 22 11 0,000 0,01292326 0,02781632 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01292326 0,02779183 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01292326 0,02776739 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01292326 0,02774299 ! regulation of embryonic development GO:0045995 35 11 0,000 0,01292326 0,02771863 ! nucleus localization GO:0051647 22 11 0,000 0,01292326 0,02769432 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01408998 0,03016812 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01408998 0,03014171 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,01408998 0,03011534 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01408998 0,03008901 ! virus-host interaction GO:0019048 30 12 0,000 0,01408998 0,03006273 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01408998 0,0300365 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01408998 0,03001031 ! protein complex disassembly GO:0043241 28 12 0,000 0,01408998 0,02998417 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01408998 0,02995808 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,01408998 0,02993203 ! hippocampus development GO:0021766 29 12 0,000 0,01408998 0,02990602 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,01408998 0,02988006 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01408998 0,02985415 ! T cell proliferation GO:0042098 32 12 0,000 0,01408998 0,02982828 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01408998 0,02980245 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01408998 0,02977667 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01408998 0,02975093 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01408998 0,02972524 ! drug transport GO:0015893 16 12 0,000 0,01408998 0,02969959 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01408998 0,02967399 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01408998 0,02964843 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01408998 0,02962292 ! polyamine metabolic process GO:0006595 18 12 0,000 0,01408998 0,02959745 ! focal adhesion formation GO:0048041 37 12 0,000 0,01408998 0,02957202 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01408998 0,02954663 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,01408998 0,02952129 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01408998 0,029496 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01408998 0,02947074 ! lipid digestion GO:0044241 21 12 0,000 0,01408998 0,02944553 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01408998 0,02942037 ! entry into host cell GO:0030260 34 12 0,000 0,01408998 0,02939524 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01408998 0,02937016 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01408998 0,02934512 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01408998 0,02932013 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01408998 0,02929517 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01408998 0,02927026 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01408998 0,02924539 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,01408998 0,02922057 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01408998 0,02919578 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01408998 0,02917104 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01408998 0,02914634 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01408998 0,02912168 ! cranial nerve development GO:0021545 23 12 0,000 0,01408998 0,02909707 ! fucose catabolic process GO:0019317 25 12 0,000 0,01408998 0,02907249 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01408998 0,02904796 ! histone acetylation GO:0016573 27 12 0,000 0,01408998 0,02902347 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01408998 0,02899901 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01408998 0,0289746 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01408998 0,02895024 ! zymogen activation GO:0031638 18 12 0,000 0,01408998 0,02892591 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01408998 0,02890162 ! T cell homeostasis GO:0043029 28 12 0,000 0,01408998 0,02887737 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01408998 0,02885317 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01408998 0,028829 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,01408998 0,02880488 ! oocyte differentiation GO:0009994 21 12 0,000 0,01408998 0,02878079 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,01408998 0,02875675 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01408998 0,02873275 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01408998 0,02870878 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,01408998 0,02868486 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01408998 0,02866097 ! defense response to fungus GO:0050832 15 12 0,000 0,01408998 0,02863713 ! developmental induction GO:0031128 22 12 0,000 0,01408998 0,02861332 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,01408998 0,02858956 ! lamellipodium assembly GO:0030032 24 12 0,000 0,01408998 0,02856583 ! response to cold GO:0009409 17 12 0,000 0,01408998 0,02854215 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01408998 0,0285185 ! localization within membrane GO:0051668 26 12 0,000 0,01408998 0,02849489 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01525536 0,03082618 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01525536 0,0308007 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01525536 0,03077527 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01525536 0,03074988 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01525536 0,03072453 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01525536 0,03069922 ! peroxisomal transport GO:0043574 28 13 0,000 0,01525536 0,03067395 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01525536 0,03064872 ! cartilage condensation GO:0001502 22 13 0,000 0,01525536 0,03062354 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01525536 0,0305984 ! organelle fusion GO:0048284 36 13 0,000 0,01525536 0,0305733 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01525536 0,03054824 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,01525536 0,03052322 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01525536 0,03049824 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01525536 0,0304733 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,01525536 0,03044841 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01525536 0,03042355 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01525536 0,03039873 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01525536 0,03037396 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01525536 0,03034923 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01525536 0,03032453 ! methionine metabolic process GO:0006555 31 13 0,000 0,01525536 0,03029988 ! plasma membrane organization GO:0007009 27 13 0,000 0,01525536 0,03027526 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01525536 0,03025069 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01525536 0,03022615 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01525536 0,03020166 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01525536 0,03017721 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01525536 0,03015279 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01525536 0,03012841 ! exocrine system development GO:0035272 34 13 0,000 0,01525536 0,03010408 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01525536 0,03007978 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01525536 0,03005552 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01525536 0,0300313 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,01525536 0,03000712 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,01525536 0,02998298 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01525536 0,02995888 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01525536 0,02993482 ! protein homotetramerization GO:0051289 24 13 0,000 0,01525536 0,02991079 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01525536 0,02988681 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01525536 0,02986286 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01525536 0,02983895 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01525536 0,02981508 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01525536 0,02979125 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01525536 0,02976745 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,01525536 0,02974369 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01525536 0,02971998 ! histone methylation GO:0016571 29 13 0,000 0,01525536 0,02969629 ! chromatin silencing GO:0006342 29 13 0,000 0,01525536 0,02967265 ! gland morphogenesis GO:0022612 31 13 0,000 0,01525536 0,02964904 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01525536 0,02962548 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01525536 0,02960195 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01525536 0,02957845 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01525536 0,029555 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01525536 0,02953158 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01525536 0,02950819 ! spleen development GO:0048536 24 13 0,000 0,01525536 0,02948485 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01525536 0,02946154 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01525536 0,02943827 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01525536 0,02941503 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01525536 0,02939184 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01525536 0,02936868 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01525536 0,02934555 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01525536 0,02932246 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01525536 0,02929941 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01525536 0,02927639 ! insulin secretion GO:0030073 24 13 0,000 0,01525536 0,02925341 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01525536 0,02923047 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01525536 0,02920756 ! acrosome reaction GO:0007340 19 13 0,000 0,01525536 0,02918469 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01525536 0,02916185 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01525536 0,02913905 ! rRNA transcription GO:0009303 28 14 0,000 0,0164194 0,03133796 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,0164194 0,03131349 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,0164194 0,03128907 ! water transport GO:0006833 21 14 0,000 0,0164194 0,03126468 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,0164194 0,03124033 ! non-recombinational repair GO:0000726 29 14 0,000 0,0164194 0,03121602 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,0164194 0,03119174 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,0164194 0,03116751 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,0164194 0,03114331 ! RNA polyadenylation GO:0043631 32 14 0,000 0,0164194 0,03111915 ! lipid localization GO:0010876 32 14 0,000 0,0164194 0,03109503 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,0164194 0,03107094 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,0164194 0,03104689 ! regulated secretory pathway GO:0045055 24 14 0,000 0,0164194 0,03102288 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,0164194 0,0309989 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,0164194 0,03097497 ! arginine metabolic process GO:0006525 21 14 0,000 0,0164194 0,03095107 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,0164194 0,0309272 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,0164194 0,03090338 ! regulation of heart rate GO:0002027 25 14 0,000 0,0164194 0,03087959 ! fear response GO:0042596 34 14 0,000 0,0164194 0,03085583 ! organic alcohol transport GO:0015850 29 14 0,000 0,0164194 0,03083212 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,0164194 0,03080844 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,0164194 0,03078479 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0164194 0,03076118 ! neutral amino acid transport GO:0015804 28 14 0,000 0,0164194 0,03073761 ! bone mineralization GO:0030282 18 14 0,000 0,0164194 0,03071408 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,0164194 0,03069058 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,0164194 0,03066711 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,0164194 0,03064368 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,0164194 0,03062029 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,0164194 0,03059694 ! regulation of cellular pH GO:0030641 27 14 0,000 0,0164194 0,03057361 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,0164194 0,03055033 ! ribosome assembly GO:0042255 18 14 0,000 0,0164194 0,03052708 ! cerebellum development GO:0021549 23 14 0,000 0,0164194 0,03050387 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,0164194 0,03048069 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,0164194 0,03045754 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,0164194 0,03043443 ! response to gamma radiation GO:0010332 30 14 0,000 0,0164194 0,03041136 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,0164194 0,03038832 ! NADP metabolic process GO:0006739 24 14 0,000 0,0164194 0,03036532 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,0164194 0,03034235 ! oxygen transport GO:0015671 22 14 0,000 0,0164194 0,03031941 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0164194 0,03029651 ! male genitalia development GO:0030539 26 14 0,000 0,0164194 0,03027365 ! regulation of RNA stability GO:0043487 33 14 0,000 0,0164194 0,03025082 ! regulation of axon extension GO:0030516 43 14 0,000 0,0164194 0,03022802 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,0164194 0,03020526 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,0164194 0,03018253 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,0164194 0,03015984 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01758209 0,03227125 ! lactation GO:0007595 30 15 0,000 0,01758209 0,03224702 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,01758209 0,03222283 ! reproductive cellular process GO:0048610 22 15 0,000 0,01758209 0,03219868 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01758209 0,03217456 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,01758209 0,03215048 ! superoxide anion generation GO:0042554 22 15 0,000 0,01758209 0,03212643 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,01758209 0,03210242 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,01758209 0,03207844 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,01758209 0,0320545 ! copper ion transport GO:0006825 22 15 0,000 0,01758209 0,0320306 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,01758209 0,03200673 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,01758209 0,0319829 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,01758209 0,0319591 ! sulfate transport GO:0008272 27 15 0,000 0,01758209 0,03193534 ! response to cAMP GO:0051591 25 15 0,000 0,01758209 0,03191162 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,01758209 0,03188793 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,01758209 0,03186427 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,01758209 0,03184065 ! response to hexose stimulus GO:0009746 25 15 0,000 0,01758209 0,03181706 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,01758209 0,03179351 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,01758209 0,03177 ! vesicle coating GO:0006901 38 15 0,000 0,01758209 0,03174652 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,01758209 0,03172307 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,01758209 0,03169966 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,01758209 0,03167628 ! regulation of exocytosis GO:0017157 26 15 0,000 0,01758209 0,03165294 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,01758209 0,03162963 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,01758209 0,03160635 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,01758209 0,03158311 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,01758209 0,03155991 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,01758209 0,03153674 ! regulation of vasodilation GO:0042312 27 15 0,000 0,01758209 0,0315136 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,01758209 0,03149049 ! histone deacetylation GO:0016575 24 15 0,000 0,01758209 0,03146742 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01758209 0,03144439 ! water homeostasis GO:0030104 28 15 0,000 0,01758209 0,03142139 ! cofactor transport GO:0051181 30 15 0,000 0,01758209 0,03139842 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01758209 0,03137548 ! muscle maintenance GO:0046716 26 15 0,000 0,01758209 0,03135258 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,01758209 0,03132971 ! intestinal absorption GO:0050892 31 15 0,000 0,01758209 0,03130688 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01758209 0,03128408 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,01758209 0,03126131 ! heme biosynthetic process GO:0006783 33 15 0,000 0,01758209 0,03123857 ! cell killing GO:0001906 32 15 0,000 0,01758209 0,03121587 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,01758209 0,0311932 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,01758209 0,03117056 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,01758209 0,03114796 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,01758209 0,03112539 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,01758209 0,03110285 ! actin filament polymerization GO:0030041 27 15 0,000 0,01758209 0,03108034 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,01758209 0,03105787 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,01874343 0,03308541 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01874343 0,03306152 ! positive regulation of cell size GO:0045793 29 16 0,000 0,01874343 0,03303767 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,01874343 0,03301385 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,01874343 0,03299006 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,01874343 0,03296631 ! bone remodeling GO:0046849 28 16 0,000 0,01874343 0,0329426 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,01874343 0,03291891 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,01874343 0,03289527 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01874343 0,03287165 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,01874343 0,03284807 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,01874343 0,03282452 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,01874343 0,03280101 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,01874343 0,03277753 ! startle response GO:0001964 28 16 0,000 0,01874343 0,03275408 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,01874343 0,03273067 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,01874343 0,03270729 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,01874343 0,03268395 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,01874343 0,03266063 ! protein polyubiquitination GO:0000209 41 16 0,000 0,01874343 0,03263736 ! glutamate metabolic process GO:0006536 25 16 0,000 0,01874343 0,03261411 ! pituitary gland development GO:0021983 30 16 0,000 0,01874343 0,0325909 ! response to osmotic stress GO:0006970 27 16 0,000 0,01874343 0,03256772 ! lysosomal transport GO:0007041 31 16 0,000 0,01874343 0,03254457 ! L-amino acid transport GO:0015807 33 16 0,000 0,01874343 0,03252146 ! stem cell development GO:0048864 46 16 0,000 0,01874343 0,03249837 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01874343 0,03247533 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01874343 0,03245231 ! intermediate filament-based process GO:0045103 36 16 0,000 0,01874343 0,03242933 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,01874343 0,03240638 ! negative regulation of immune response GO:0050777 38 16 0,000 0,01874343 0,03238346 ! axon cargo transport GO:0008088 46 16 0,000 0,01874343 0,03236057 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,01874343 0,03233772 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,01874343 0,0323149 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,01874343 0,03229211 ! DNA replication initiation GO:0006270 28 16 0,000 0,01874343 0,03226935 ! neuron recognition GO:0008038 40 16 0,000 0,01874343 0,03224663 ! mRNA splice site selection GO:0006376 44 16 0,000 0,01874343 0,03222393 ! tissue regeneration GO:0042246 27 16 0,000 0,01874343 0,03220127 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,01874343 0,03217864 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,01874343 0,03215605 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,01874343 0,03213348 ! biomineral formation GO:0031214 22 16 0,000 0,01874343 0,03211095 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,01874343 0,03208844 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,01874343 0,03206597 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,01874343 0,03204353 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01874343 0,03202113 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,01874343 0,03199875 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,01874343 0,0319764 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,01874343 0,03195409 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,01874343 0,03193181 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01874343 0,03190955 ! peptide hormone processing GO:0016486 27 16 0,000 0,01874343 0,03188733 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,01990344 0,03383724 ! metencephalon development GO:0022037 32 17 0,000 0,01990344 0,03381371 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,01990344 0,03379021 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,01990344 0,03376674 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,01990344 0,03374331 ! signal complex assembly GO:0007172 47 17 0,000 0,01990344 0,03371991 ! filopodium assembly GO:0046847 42 17 0,000 0,01990344 0,03369654 ! endothelial cell migration GO:0043542 31 17 0,000 0,01990344 0,03367321 ! gene silencing by RNA GO:0031047 38 17 0,000 0,01990344 0,0336499 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,01990344 0,03362663 ! glial cell development GO:0021782 28 17 0,000 0,01990344 0,03360339 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,01990344 0,03358019 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,01990344 0,03355701 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,01990344 0,03353387 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,01990344 0,03351076 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,01990344 0,03348768 ! myoblast differentiation GO:0045445 50 17 0,000 0,01990344 0,03346463 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,01990344 0,03344162 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,01990344 0,03341863 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,01990344 0,03339568 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,01990344 0,03337276 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,01990344 0,03334987 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,01990344 0,03332701 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,01990344 0,03330418 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,01990344 0,03328139 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,01990344 0,03325863 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,01990344 0,03323589 ! regulation of protein binding GO:0043393 33 17 0,000 0,01990344 0,03321319 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,01990344 0,03319052 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,01990344 0,03316788 ! genitalia development GO:0048806 32 17 0,000 0,01990344 0,03314527 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,01990344 0,03312269 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,01990344 0,03310014 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,01990344 0,03307763 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,01990344 0,03305514 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,01990344 0,03303268 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,01990344 0,03301026 ! steroid catabolic process GO:0006706 34 17 0,000 0,01990344 0,03298786 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,01990344 0,0329655 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,01990344 0,03294316 ! gas transport GO:0015669 26 17 0,000 0,01990344 0,03292086 ! organic cation transport GO:0015695 32 17 0,000 0,01990344 0,03289859 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,01990344 0,03287634 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,01990344 0,03285413 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,01990344 0,03283194 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,02106211 0,0347198 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,02106211 0,03469639 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,02106211 0,03467301 ! limbic system development GO:0021761 40 18 0,000 0,02106211 0,03464966 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02106211 0,03462634 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,02106211 0,03460305 ! adult walking behavior GO:0007628 36 18 0,000 0,02106211 0,0345798 ! patterning of blood vessels GO:0001569 43 18 0,000 0,02106211 0,03455657 ! heart looping GO:0001947 34 18 0,000 0,02106211 0,03453338 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,02106211 0,03451022 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,02106211 0,03448709 ! centrosome cycle GO:0007098 26 18 0,000 0,02106211 0,03446399 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,02106211 0,03444092 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,02106211 0,03441789 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,02106211 0,03439488 ! glycine metabolic process GO:0006544 30 18 0,000 0,02106211 0,0343719 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02106211 0,03434896 ! response to retinoic acid GO:0032526 31 18 0,000 0,02106211 0,03432604 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,02106211 0,03430316 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,02106211 0,03428031 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,02106211 0,03425748 ! DNA integration GO:0015074 32 18 0,000 0,02106211 0,03423469 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,02106211 0,03421193 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,02106211 0,0341892 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,02106211 0,03416649 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,02106211 0,03414382 ! neural crest cell migration GO:0001755 41 18 0,000 0,02106211 0,03412118 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,02106211 0,03409857 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,02106211 0,03407599 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,02106211 0,03405343 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,02106211 0,03403091 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,02106211 0,03400842 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,02106211 0,03398596 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,02106211 0,03396352 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,02106211 0,03394112 ! detection of bacterium GO:0016045 22 18 0,000 0,02106211 0,03391875 ! nerve development GO:0021675 34 18 0,000 0,02106211 0,0338964 ! defense response to virus GO:0051607 43 18 0,000 0,02106211 0,03387409 ! microspike assembly GO:0030035 46 18 0,000 0,02106211 0,0338518 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,02106211 0,03382955 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,02106211 0,03380732 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,02221944 0,03564156 ! positive regulation of translation GO:0045727 31 19 0,000 0,02221944 0,03561818 ! negative regulation of defense response GO:0031348 27 19 0,000 0,02221944 0,03559482 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,02221944 0,0355715 ! neuron maturation GO:0042551 46 19 0,000 0,02221944 0,0355482 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,02221944 0,03552494 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,02221944 0,0355017 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,02221944 0,0354785 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,02221944 0,03545533 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,02221944 0,03543218 ! inositol metabolic process GO:0006020 33 19 0,000 0,02221944 0,03540907 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02221944 0,03538599 ! memory GO:0007613 34 19 0,000 0,02221944 0,03536293 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,02221944 0,03533991 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,02221944 0,03531692 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,02221944 0,03529396 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,02221944 0,03527102 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,02221944 0,03524812 ! cerebral cortex development GO:0021987 40 19 0,000 0,02221944 0,03522525 ! pigmentation during development GO:0048066 42 19 0,000 0,02221944 0,0352024 ! response to vitamin A GO:0033189 32 19 0,000 0,02221944 0,03517959 ! heme metabolic process GO:0042168 40 19 0,000 0,02221944 0,0351568 ! neuromuscular junction development GO:0007528 43 19 0,000 0,02221944 0,03513405 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,02221944 0,03511132 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,02221944 0,03508862 ! response to fungus GO:0009620 26 19 0,000 0,02221944 0,03506596 ! peptide cross-linking GO:0018149 39 19 0,000 0,02221944 0,03504332 ! protein export from nucleus GO:0006611 40 19 0,000 0,02221944 0,03502071 ! heart process GO:0003015 32 19 0,000 0,02221944 0,03499813 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,02221944 0,03497558 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,02221944 0,03495306 ! visual learning GO:0008542 38 19 0,000 0,02221944 0,03493057 ! cellular pigmentation GO:0033059 37 19 0,000 0,02221944 0,0349081 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,02221944 0,03488567 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,02221944 0,03486326 ! vitamin transport GO:0051180 31 19 0,000 0,02221944 0,03484089 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,02221944 0,03481854 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,02221944 0,03479622 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,02221944 0,03477393 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,02221944 0,03475167 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,02221944 0,03472943 ! cilium assembly GO:0042384 38 19 0,000 0,02221944 0,03470723 ! peptide hormone secretion GO:0030072 32 19 0,000 0,02221944 0,03468505 ! protein secretion GO:0009306 45 20 0,000 0,02337544 0,03646629 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,02337544 0,03644301 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,02337544 0,03641977 ! positive regulation of ossification GO:0045778 50 20 0,000 0,02337544 0,03639656 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,02337544 0,03637338 ! skin development GO:0043588 42 20 0,000 0,02337544 0,03635022 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,02337544 0,0363271 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,02337544 0,03630401 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,02337544 0,03628094 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,02337544 0,03625791 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,02337544 0,0362349 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,02337544 0,03621192 ! response to vitamin GO:0033273 36 20 0,000 0,02337544 0,03618898 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,02337544 0,03616606 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,02337544 0,03614317 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,02337544 0,03612031 ! bile acid metabolic process GO:0008206 34 20 0,000 0,02337544 0,03609747 ! response to alkaloid GO:0043279 38 20 0,000 0,02337544 0,03607467 ! retinoid metabolic process GO:0001523 34 20 0,000 0,02337544 0,0360519 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,02337544 0,03602915 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,02337544 0,03600643 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,02337544 0,03598374 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,02337544 0,03596108 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,02337544 0,03593845 ! actin filament bundle formation GO:0051017 47 20 0,000 0,02337544 0,03591585 ! body fluid secretion GO:0007589 33 20 0,000 0,02337544 0,03589328 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,02337544 0,03587073 ! peptide secretion GO:0002790 38 20 0,000 0,02337544 0,03584821 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,02337544 0,03582572 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,02337544 0,03580326 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,02337544 0,03578083 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,02337544 0,03575842 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,02337544 0,03573605 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,02337544 0,0357137 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,02337544 0,03569138 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,02337544 0,03566908 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,02337544 0,03564682 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,02337544 0,03562458 ! regulation of glucose import GO:0046324 30 20 0,000 0,02337544 0,03560237 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,02337544 0,03558019 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,02337544 0,03555803 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,02337544 0,03553591 ! negative regulation of translation GO:0017148 32 20 0,000 0,02337544 0,03551381 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,02337544 0,03549174 ! regulation of cell killing GO:0031341 46 21 0,000 0,0245301 0,03722177 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,0245301 0,03719866 ! hormone secretion GO:0046879 39 21 0,000 0,0245301 0,03717559 ! lipid phosphorylation GO:0046834 43 21 0,000 0,0245301 0,03715254 ! cAMP metabolic process GO:0046058 41 21 0,000 0,0245301 0,03712952 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,0245301 0,03710653 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,0245301 0,03708357 ! ovarian follicle development GO:0001541 39 21 0,000 0,0245301 0,03706063 ! smooth muscle contraction GO:0006939 48 21 0,000 0,0245301 0,03703773 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,0245301 0,03701485 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,0245301 0,036992 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,0245301 0,03696918 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,0245301 0,03694639 ! plasma membrane fusion GO:0045026 33 21 0,000 0,0245301 0,03692363 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,0245301 0,03690089 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,0245301 0,03687818 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,0245301 0,0368555 ! sensory perception of pain GO:0019233 33 21 0,000 0,0245301 0,03683285 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,0245301 0,03681022 ! diencephalon development GO:0021536 36 21 0,000 0,0245301 0,03678763 ! collagen fibril organization GO:0030199 62 21 0,000 0,0245301 0,03676506 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,0245301 0,03674252 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,0245301 0,03672 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,0245301 0,03669752 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,0245301 0,03667506 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,0245301 0,03665263 ! collagen catabolic process GO:0030574 29 21 0,000 0,0245301 0,03663022 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,0245301 0,03660785 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,0245301 0,0365855 ! sperm-egg recognition GO:0035036 23 21 0,000 0,0245301 0,03656317 ! actin filament-based movement GO:0030048 47 21 0,000 0,0245301 0,03654088 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,0245301 0,03651861 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,02568343 0,03821232 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,02568343 0,03818906 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,02568343 0,03816583 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,02568343 0,03814263 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,02568343 0,03811946 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,02568343 0,03809631 ! microtubule-based transport GO:0010970 59 22 0,000 0,02568343 0,0380732 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,02568343 0,03805011 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,02568343 0,03802705 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,02568343 0,03800401 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,02568343 0,03798101 ! cellular response to starvation GO:0009267 37 22 0,000 0,02568343 0,03795803 ! vacuolar transport GO:0007034 41 22 0,000 0,02568343 0,03793508 ! central nervous system neuron development GO:0021954 47 22 0,000 0,02568343 0,03791216 ! fucose metabolic process GO:0006004 44 22 0,000 0,02568343 0,03788927 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,02568343 0,0378664 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,02568343 0,03784356 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,02568343 0,03782075 ! ureteric bud development GO:0001657 50 22 0,000 0,02568343 0,03779797 ! cell aging GO:0007569 48 22 0,000 0,02568343 0,03777521 ! stem cell differentiation GO:0048863 57 22 0,000 0,02568343 0,03775248 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,02568343 0,03772978 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,02568343 0,03770711 ! cytolysis GO:0019835 27 22 0,000 0,02568343 0,03768446 ! renal system process GO:0003014 42 22 0,000 0,02568343 0,03766184 ! vasodilation GO:0042311 40 22 0,000 0,02568343 0,03763925 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,02568343 0,03761668 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,02568343 0,03759415 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,02568343 0,03757163 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,02568343 0,03754915 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,02568343 0,03752669 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,02568343 0,03750426 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,02568343 0,03748186 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,02568343 0,03745948 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,02568343 0,03743713 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,02568343 0,03741481 ! sarcomere organization GO:0045214 32 22 0,000 0,02568343 0,03739251 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,02568343 0,03737024 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,02568343 0,03734799 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,02568343 0,03732578 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,02568343 0,03730358 ! gut development GO:0048565 44 22 0,000 0,02568343 0,03728142 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,02568343 0,03725928 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,02568343 0,03723717 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,02568343 0,03721508 ! protein stabilization GO:0050821 41 22 0,000 0,02568343 0,03719302 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,02683543 0,03883825 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,02683543 0,03881525 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,02683543 0,03879228 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,02683543 0,03876934 ! gluconeogenesis GO:0006094 38 23 0,000 0,02683543 0,03874643 ! glycerol metabolic process GO:0006071 40 23 0,000 0,02683543 0,03872354 ! viral genome replication GO:0019079 44 23 0,000 0,02683543 0,03870069 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,02683543 0,03867785 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,02683543 0,03865505 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,02683543 0,03863227 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,02683543 0,03860952 ! regeneration GO:0031099 42 23 0,000 0,02683543 0,03858679 ! axis specification GO:0009798 43 23 0,000 0,02683543 0,03856409 ! visual behavior GO:0007632 46 23 0,000 0,02683543 0,03854142 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,02683543 0,03851878 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,02683543 0,03849616 ! response to ethanol GO:0045471 47 23 0,000 0,02683543 0,03847357 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,02683543 0,038451 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,02683543 0,03842846 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,02683543 0,03840595 ! peroxisome organization GO:0007031 43 23 0,000 0,02683543 0,03838347 ! lysosome organization GO:0007040 47 23 0,000 0,02683543 0,03836101 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,02683543 0,03833857 ! vesicle targeting GO:0006903 49 23 0,000 0,02683543 0,03831617 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,02683543 0,03829379 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,02683543 0,03827143 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,02683543 0,0382491 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,02683543 0,0382268 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,02683543 0,03820452 ! DNA modification GO:0006304 36 23 0,000 0,02683543 0,03818227 ! fatty acid transport GO:0015908 47 23 0,000 0,02683543 0,03816005 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,02683543 0,03813785 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,02683543 0,03811567 ! hormone transport GO:0009914 41 23 0,000 0,02683543 0,03809353 ! cell-cell recognition GO:0009988 28 23 0,000 0,02683543 0,03807141 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,02683543 0,03804931 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,02683543 0,03802724 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,02683543 0,03800519 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,0279861 0,03961185 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,0279861 0,03958891 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,0279861 0,039566 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,0279861 0,03954311 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,0279861 0,03952026 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,0279861 0,03949743 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,0279861 0,03947462 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,0279861 0,03945184 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,0279861 0,03942909 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,0279861 0,03940637 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,0279861 0,03938367 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,0279861 0,03936099 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,0279861 0,03933835 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,0279861 0,03931572 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,0279861 0,03929313 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,0279861 0,03927056 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,0279861 0,03924802 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,0279861 0,0392255 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,0279861 0,03920301 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,0279861 0,03918054 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,0279861 0,0391581 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,0279861 0,03913569 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,0279861 0,0391133 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,0279861 0,03909093 ! membrane depolarization GO:0051899 45 24 0,000 0,0279861 0,0390686 ! pallium development GO:0021543 56 24 0,000 0,0279861 0,03904629 ! oogenesis GO:0048477 44 24 0,000 0,0279861 0,039024 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,0279861 0,03900174 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,0279861 0,0389795 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,0279861 0,03895729 ! platelet activation GO:0030168 41 24 0,000 0,0279861 0,03893511 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,0279861 0,03891295 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,0279861 0,03889081 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,0279861 0,0388687 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,0279861 0,03884662 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,0279861 0,03882456 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,0279861 0,03880252 ! regulation of amine transport GO:0051952 41 24 0,000 0,0279861 0,03878051 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,0279861 0,03875853 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,02913544 0,04032741 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,02913544 0,04030458 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,02913544 0,04028177 ! leukocyte adhesion GO:0007159 55 25 0,000 0,02913544 0,04025898 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,02913544 0,04023623 ! phototransduction GO:0007602 37 25 0,000 0,02913544 0,04021349 ! keratinization GO:0031424 37 25 0,000 0,02913544 0,04019079 ! vasculogenesis GO:0001570 49 25 0,000 0,02913544 0,04016811 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,02913544 0,04014545 ! vacuole organization GO:0007033 49 25 0,000 0,02913544 0,04012282 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,02913544 0,04010022 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,02913544 0,04007764 ! receptor metabolic process GO:0043112 53 25 0,000 0,02913544 0,04005508 ! chromosome condensation GO:0030261 48 25 0,000 0,02913544 0,04003256 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,02913544 0,04001005 ! regulation of behavior GO:0050795 48 25 0,000 0,02913544 0,03998758 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,02913544 0,03996512 ! interaction with host GO:0051701 66 25 0,000 0,02913544 0,0399427 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,02913544 0,03992029 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,02913544 0,03989792 ! immunoglobulin production GO:0002377 62 25 0,000 0,02913544 0,03987557 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,02913544 0,03985324 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,02913544 0,03983094 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,02913544 0,03980866 ! liver development GO:0001889 55 25 0,000 0,02913544 0,03978641 ! protein tetramerization GO:0051262 57 25 0,000 0,02913544 0,03976418 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,03028346 0,04130792 ! myelination GO:0042552 50 26 0,000 0,03028346 0,04128487 ! initiation of viral infection GO:0019059 60 26 0,000 0,03028346 0,04126184 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,03028346 0,04123884 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,03028346 0,04121587 ! molting cycle process GO:0022404 52 26 0,000 0,03028346 0,04119292 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,03028346 0,04117 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,03028346 0,0411471 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,03028346 0,04112423 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,03028346 0,04110138 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,03028346 0,04107856 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,03028346 0,04105576 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,03028346 0,04103299 ! digestive system process GO:0022600 49 26 0,000 0,03028346 0,04101025 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,03028346 0,04098753 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,03028346 0,04096483 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,03028346 0,04094216 ! neural crest cell development GO:0014032 59 26 0,000 0,03028346 0,04091951 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,03028346 0,04089689 ! negative regulation of cell development GO:0010721 83 26 0,000 0,03028346 0,0408743 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,03028346 0,04085173 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,03028346 0,04082918 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,03028346 0,04080666 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,03028346 0,04078417 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,03028346 0,0407617 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,03028346 0,04073925 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,03028346 0,04071683 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,03028346 0,04069444 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,03028346 0,04067206 ! blastocyst development GO:0001824 50 26 0,000 0,03028346 0,04064972 ! telomere organization GO:0032200 46 26 0,000 0,03028346 0,04062739 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,03028346 0,04060509 ! neural tube closure GO:0001843 58 26 0,000 0,03028346 0,04058282 GO:0060606|tube closure, ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,03028346 0,04056057 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,03028346 0,04053835 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,03143014 0,0420503 ! embryonic pattern specification GO:0009880 49 27 0,000 0,03143014 0,04202728 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,03143014 0,04200429 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,03143014 0,04198133 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,03143014 0,04195838 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,03143014 0,04193547 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,03143014 0,04191258 ! iron ion transport GO:0006826 65 27 0,000 0,03143014 0,04188971 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,03143014 0,04186687 ! superoxide metabolic process GO:0006801 41 27 0,000 0,03143014 0,04184406 ! tube lumen formation GO:0035148 59 27 0,000 0,03143014 0,04182127 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,03143014 0,0417985 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,03143014 0,04177576 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,03143014 0,04175304 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,03143014 0,04173035 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,03143014 0,04170768 ! response to starvation GO:0042594 47 27 0,000 0,03143014 0,04168504 ! response to toxin GO:0009636 49 27 0,000 0,03143014 0,04166242 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,03143014 0,04163983 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,03143014 0,04161726 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,03143014 0,04159471 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,03143014 0,04157219 ! leukocyte proliferation GO:0070661 59 27 0,000 0,03143014 0,0415497 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,03143014 0,04152723 ! neuron fate commitment GO:0048663 52 28 0,000 0,03257551 0,04301728 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,03257551 0,04299404 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,03257551 0,04297083 ! protein amino acid acylation GO:0043543 59 28 0,000 0,03257551 0,04294764 ! vesicle docking GO:0048278 55 28 0,000 0,03257551 0,04292447 ! circadian rhythm GO:0007623 56 28 0,000 0,03257551 0,04290133 ! dendrite development GO:0016358 67 28 0,000 0,03257551 0,04287822 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,03257551 0,04285513 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,03257551 0,04283206 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,03257551 0,04280902 ! base-excision repair GO:0006284 41 28 0,000 0,03257551 0,04278601 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,03257551 0,04276301 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,03257551 0,04274005 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,03257551 0,04271711 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,03257551 0,04269419 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,03257551 0,0426713 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,03257551 0,04264843 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,03257551 0,04262559 ! glutathione metabolic process GO:0006749 42 28 0,000 0,03257551 0,04260277 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,03257551 0,04257997 ! lipid oxidation GO:0034440 48 28 0,000 0,03257551 0,0425572 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,03257551 0,04253446 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,03257551 0,04251174 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,03371955 0,04398124 ! translational initiation GO:0006413 66 29 0,000 0,03371955 0,04395777 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,03371955 0,04393433 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,03371955 0,04391091 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,03371955 0,04388752 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,03371955 0,04386415 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,03371955 0,0438408 ! primary neural tube formation GO:0014020 61 29 0,000 0,03371955 0,04381748 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,03371955 0,04379419 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,03371955 0,04377092 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,03371955 0,04374767 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,03371955 0,04372445 ! somitogenesis GO:0001756 52 29 0,000 0,03371955 0,04370126 ! synaptogenesis GO:0007416 46 29 0,000 0,03371955 0,04367808 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,03371955 0,04365494 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,03371955 0,04363182 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,03371955 0,04360872 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,03371955 0,04358564 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,03486228 0,04503889 ! phenol metabolic process GO:0018958 56 30 0,000 0,03486228 0,04501508 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,03486228 0,0449913 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,03486228 0,04496755 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,03486228 0,04494382 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,03486228 0,04492012 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,03486228 0,04489644 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,03486228 0,04487278 ! acute-phase response GO:0006953 50 30 0,000 0,03486228 0,04484915 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,03486228 0,04482555 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,03486228 0,04480197 ! myofibril assembly GO:0030239 50 30 0,000 0,03486228 0,04477841 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,03486228 0,04475488 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,03486228 0,04473138 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,03486228 0,04470789 ! cell fate determination GO:0001709 64 30 0,000 0,03486228 0,04468444 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,03486228 0,04466101 ! phospholipid transport GO:0015914 65 30 0,000 0,03486228 0,0446376 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,03486228 0,04461422 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,03486228 0,04459086 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,03486228 0,04456752 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,03486228 0,04454421 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,03486228 0,04452093 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,03486228 0,04449767 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,03600368 0,04593054 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,03600368 0,04590657 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,03600368 0,04588262 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,03600368 0,0458587 ! cell junction assembly GO:0034329 85 31 0,000 0,03600368 0,0458348 ! regulation of innate immune response GO:0045088 57 31 0,000 0,03600368 0,04581093 ! ovulation cycle process GO:0022602 55 31 0,000 0,03600368 0,04578708 ! peptide transport GO:0015833 60 31 0,000 0,03600368 0,04576326 ! male gonad development GO:0008584 56 31 0,000 0,03600368 0,04573946 ! iron ion homeostasis GO:0055072 60 31 0,000 0,03600368 0,04571569 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,03600368 0,04569194 ! detection of light stimulus GO:0009583 44 31 0,000 0,03600368 0,04566822 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,03600368 0,04564452 ! natural killer cell activation GO:0030101 50 31 0,000 0,03600368 0,04562084 ! ensheathment of neurons GO:0007272 64 31 0,000 0,03600368 0,04559719 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,03600368 0,04557357 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,03600368 0,04554997 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,03600368 0,04552639 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,03600368 0,04550284 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,03714376 0,04691945 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,03714376 0,0468952 ! collagen metabolic process GO:0032963 49 32 0,000 0,03714376 0,04687098 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,03714376 0,04684678 ! spindle organization GO:0007051 50 32 0,000 0,03714376 0,04682261 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,03714376 0,04679846 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,03714376 0,04677434 ! metanephros development GO:0001656 81 32 0,000 0,03714376 0,04675024 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,03714376 0,04672617 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,03714376 0,04670212 ! muscle cell development GO:0055001 52 32 0,000 0,03714376 0,04667809 ! mesoderm formation GO:0001707 73 32 0,000 0,03714376 0,04665409 ! ovulation cycle GO:0042698 57 32 0,000 0,03714376 0,04663012 ! peripheral nervous system development GO:0007422 68 32 0,000 0,03714376 0,04660617 ! BMP signaling pathway GO:0030509 71 32 0,000 0,03714376 0,04658225 ! hindbrain development GO:0030902 65 32 0,000 0,03714376 0,04655834 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,03714376 0,04653447 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,03714376 0,04651062 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,03714376 0,04648679 ! gene silencing GO:0016458 71 32 0,000 0,03714376 0,04646299 ! regulation of pH GO:0006885 56 33 0,000 0,03828253 0,04786296 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,03828253 0,04783848 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,03828253 0,04781402 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,03828253 0,04778959 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,03828253 0,04776518 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,03828253 0,0477408 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,03828253 0,04771644 ! response to ionizing radiation GO:0010212 74 33 0,000 0,03828253 0,04769211 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,03828253 0,0476678 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,03828253 0,04764352 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,03828253 0,04761926 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,03828253 0,04759503 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,03828253 0,04757082 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,03828253 0,04754663 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,03828253 0,04752247 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,03941999 0,04890961 ! glial cell differentiation GO:0010001 67 34 0,000 0,03941999 0,04888479 ! post-embryonic development GO:0009791 76 34 0,000 0,03941999 0,04885998 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,03941999 0,04883521 ! cholesterol transport GO:0030301 62 34 0,000 0,03941999 0,04881045 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,03941999 0,04878573 ! spliceosome assembly GO:0000245 75 34 0,000 0,03941999 0,04876103 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,03941999 0,04873635 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,03941999 0,0487117 ! formation of primary germ layer GO:0001704 76 34 0,000 0,03941999 0,04868707 ! cell fate specification GO:0001708 56 34 0,000 0,03941999 0,04866247 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,03941999 0,04863789 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,03941999 0,04861334 ! adult locomotory behavior GO:0008344 62 34 0,000 0,03941999 0,04858881 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,03941999 0,04856431 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,04055613 0,04993882 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,04055613 0,04991366 ! negative regulation of secretion GO:0051048 68 35 0,000 0,04055613 0,04988853 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,04055613 0,04986342 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,04055613 0,04983834 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,04055613 0,04981328 ! membrane docking GO:0022406 69 35 0,000 0,04055613 0,04978825 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,04055613 0,04976324 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,04055613 0,04973826 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,04055613 0,04971331 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,04055613 0,04968837 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,04055613 0,04966347 ! ceramide metabolic process GO:0006672 72 35 0,000 0,04055613 0,04963859 ! telencephalon development GO:0021537 81 35 0,000 0,04055613 0,04961373 ! sterol transport GO:0015918 63 35 0,000 0,04055613 0,0495889 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,04055613 0,04956409 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,04055613 0,04953931 ! placenta development GO:0001890 53 35 0,000 0,04055613 0,04951455 ! vesicle localization GO:0051648 70 35 0,000 0,04055613 0,04948982 ! regulation of muscle development GO:0048634 82 36 0,000 0,04169096 0,05084923 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,04169096 0,05082386 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,04169096 0,05079851 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,04169096 0,05077318 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,04169096 0,05074789 ! positive regulation of cell development GO:0010720 85 36 0,000 0,04169096 0,05072261 ! regulation of proteolysis GO:0030162 77 36 0,000 0,04169096 0,05069736 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,04169096 0,05067214 ! aerobic respiration GO:0009060 56 36 0,000 0,04169096 0,05064694 ! cytokine production GO:0001816 68 36 0,000 0,04169096 0,05062177 ! embryonic organ development GO:0048568 67 36 0,000 0,04169096 0,05059662 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,04169096 0,0505715 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,04282447 0,05192069 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,04282447 0,05189494 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,04282447 0,05186921 ! sister chromatid segregation GO:0000819 65 37 0,000 0,04282447 0,0518435 ! odontogenesis GO:0042476 74 37 0,000 0,04282447 0,05181783 ! actomyosin structure organization GO:0031032 68 37 0,000 0,04282447 0,05179217 ! tissue remodeling GO:0048771 78 37 0,000 0,04282447 0,05176655 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,04282447 0,05174095 ! female gonad development GO:0008585 71 37 0,000 0,04282447 0,05171537 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,04282447 0,05168982 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,04282447 0,05166429 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,04282447 0,05163879 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,04282447 0,05161332 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,04395668 0,05295177 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,04395668 0,05292567 ! meiosis I GO:0007127 74 38 0,000 0,04395668 0,0528996 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,04395668 0,05287355 ! organic anion transport GO:0015711 82 38 0,000 0,04395668 0,05284753 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,04395668 0,05282153 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,04395668 0,05279557 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,04395668 0,05276962 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,04395668 0,0527437 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,04395668 0,05271781 ! regulation of protein stability GO:0031647 77 38 0,000 0,04395668 0,05269194 ! spermatid development GO:0007286 69 38 0,000 0,04395668 0,0526661 ! glycogen metabolic process GO:0005977 63 38 0,000 0,04395668 0,05264028 ! pigment metabolic process GO:0042440 87 38 0,000 0,04395668 0,05261449 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,04395668 0,05258873 ! neural tube formation GO:0001841 79 38 0,000 0,04395668 0,05256299 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,04508759 0,05388893 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,04508759 0,05386258 ! negative regulation of binding GO:0051100 71 39 0,000 0,04508759 0,05383625 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,04508759 0,05380995 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,04508759 0,05378368 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,04508759 0,05375743 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,04508759 0,05373121 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,04508759 0,05370501 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,04508759 0,05367884 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,04508759 0,05365269 ! glucan metabolic process GO:0044042 64 39 0,000 0,04508759 0,05362657 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,04621718 0,05494335 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,04621718 0,05491662 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,04621718 0,05488993 ! learning GO:0007612 82 40 0,000 0,04621718 0,05486326 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,04621718 0,05483661 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,04621718 0,05480999 ! lipid homeostasis GO:0055088 75 40 0,000 0,04621718 0,0547834 ! mismatch repair GO:0006298 58 40 0,000 0,04621718 0,05475683 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,04621718 0,05473029 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,04621718 0,05470377 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,04621718 0,05467728 ! RNA export from nucleus GO:0006405 61 41 0,000 0,04734548 0,05598499 ! mRNA catabolic process GO:0006402 79 41 0,000 0,04734548 0,05595791 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,04734548 0,05593085 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,04734548 0,05590382 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,04734548 0,05587681 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,04734548 0,05584983 ! gliogenesis GO:0042063 91 41 0,000 0,04734548 0,05582287 ! feeding behavior GO:0007631 69 41 0,000 0,04734548 0,05579595 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,04734548 0,05576904 ! mesenchymal cell development GO:0014031 94 41 0,000 0,04734548 0,05574217 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,04734548 0,05571532 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,04734548 0,05568849 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,04734548 0,05566169 ! spermatid differentiation GO:0048515 73 41 0,000 0,04734548 0,05563492 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,04734548 0,05560817 ! RNA modification GO:0009451 64 41 0,000 0,04734548 0,05558145 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,04847246 0,05687715 ! ear morphogenesis GO:0042471 64 42 0,000 0,04847246 0,05684985 ! organic ether metabolic process GO:0018904 59 42 0,000 0,04847246 0,05682257 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,04847246 0,05679531 ! T cell differentiation GO:0030217 93 42 0,000 0,04847246 0,05676809 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,04847246 0,05674089 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,04847246 0,05671371 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,04847246 0,05668656 ! regulation of protein secretion GO:0050708 77 42 0,000 0,04847246 0,05665944 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,04847246 0,05663234 ! cytokinesis GO:0000910 84 42 0,000 0,04847246 0,05660527 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,04847246 0,05657823 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,04959815 0,05786451 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,04959815 0,05783689 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,04959815 0,0578093 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,04959815 0,05778173 ! regulation of tube size GO:0035150 76 43 0,000 0,04959815 0,05775419 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,04959815 0,05772667 ! glucose transport GO:0015758 66 43 0,000 0,04959815 0,05769918 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,04959815 0,05767172 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,04959815 0,05764428 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,04959815 0,05761687 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,04959815 0,05758949 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,04959815 0,05756213 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,04959815 0,0575348 ! segmentation GO:0035282 78 43 0,000 0,04959815 0,05750749 ! ion transmembrane transport GO:0034220 79 43 0,000 0,04959815 0,05748021 ! neuron migration GO:0001764 85 43 0,000 0,04959815 0,05745296 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,04959815 0,05742573 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,05072254 0,05869975 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,05072254 0,05867195 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,05072254 0,05864419 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,05072254 0,05861644 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,05072254 0,05858873 ! hexose transport GO:0008645 68 44 0,000 0,05072254 0,05856104 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,05072254 0,05853338 ! striated muscle contraction GO:0006941 85 44 0,000 0,05072254 0,05850574 ! phagocytosis GO:0006909 105 44 0,000 0,05072254 0,05847813 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,05072254 0,05845055 ! double-strand break repair GO:0006302 85 44 0,000 0,05072254 0,05842299 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,05184563 0,05968844 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,05184563 0,05966032 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,05184563 0,05963224 ! keratinocyte differentiation GO:0030216 81 45 0,000 0,05184563 0,05960417 ! biopolymer methylation GO:0043414 91 45 0,000 0,05184563 0,05957614 ! B cell differentiation GO:0030183 124 45 0,000 0,05184563 0,05954813 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,05184563 0,05952015 ! female gamete generation GO:0007292 71 45 0,000 0,05184563 0,05949219 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,05184563 0,05946426 ! developmental growth GO:0048589 88 45 0,000 0,05184563 0,05943635 ! maintenance of location in cell GO:0051651 101 45 0,000 0,05184563 0,05940848 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,05296742 0,06066545 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,05296742 0,06063702 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,05296742 0,06060862 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,05296742 0,06058025 ! leukocyte migration GO:0050900 75 46 0,000 0,05296742 0,0605519 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,05296742 0,06052358 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,05296742 0,06049528 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,05296742 0,06046701 ! pigmentation GO:0043473 103 46 0,000 0,05296742 0,06043877 ! cell growth GO:0016049 90 46 0,000 0,05296742 0,06041055 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,05296742 0,06038236 ! neural tube development GO:0021915 91 47 0,000 0,05408792 0,06163096 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,05408792 0,06160223 ! response to insulin stimulus GO:0032868 98 47 0,000 0,05408792 0,06157352 ! positive regulation of defense response GO:0031349 88 48 0,000 0,05520712 0,06281835 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,05520712 0,0627891 ! mitochondrial transport GO:0006839 94 48 0,000 0,05520712 0,06275988 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,05520712 0,06273069 ! cellular component disassembly GO:0022411 89 48 0,000 0,05520712 0,06270153 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,05520712 0,06267239 ! endosome transport GO:0016197 127 48 0,000 0,05520712 0,06264328 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,05520712 0,0626142 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,05520712 0,06258515 ! male sex differentiation GO:0046661 93 48 0,000 0,05520712 0,06255612 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,05520712 0,06252712 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,05520712 0,06249814 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,05520712 0,06246919 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,05520712 0,06244027 ! methylation GO:0032259 97 48 0,000 0,05520712 0,06241138 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,05632503 0,06364572 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,05632503 0,06361629 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,05632503 0,06358689 ! JNK cascade GO:0007254 106 49 0,000 0,05632503 0,06355752 ! protein homooligomerization GO:0051260 84 49 0,000 0,05632503 0,06352818 ! regulation of action potential GO:0001508 102 50 0,000 0,05744164 0,0647577 ! regulation of ion transport GO:0043269 86 50 0,000 0,05744164 0,06472783 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,05744164 0,06469799 ! endocrine system development GO:0035270 109 50 0,000 0,05744164 0,06466817 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,05744164 0,06463839 ! activation of caspase activity GO:0006919 95 50 0,000 0,05744164 0,06460863 ! regulation of ossification GO:0030278 123 50 0,000 0,05744164 0,06457889 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,05744164 0,06454919 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,05744164 0,06451951 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,05744164 0,06448986 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,05744164 0,06446024 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,05744164 0,06443064 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,05855697 0,06565153 ! viral infectious cycle GO:0019058 104 51 0,000 0,05855697 0,06562141 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,05855697 0,06559133 ! peptide metabolic process GO:0006518 80 51 0,000 0,05855697 0,06556127 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,05855697 0,06553123 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,05855697 0,06550123 ! positive regulation of binding GO:0051099 88 52 0,000 0,05967101 0,06671683 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,05967101 0,06668631 ! Notch signaling pathway GO:0007219 111 52 0,000 0,05967101 0,06665582 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,05967101 0,06662536 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,05967101 0,06659492 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,05967101 0,06656451 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,05967101 0,06653413 ! excretion GO:0007588 87 52 0,000 0,05967101 0,06650378 ! histone modification GO:0016570 104 52 0,000 0,05967101 0,06647345 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,05967101 0,06644316 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,05967101 0,06641288 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,05967101 0,06638264 ! amino acid activation GO:0043038 98 52 0,000 0,05967101 0,06635243 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of growth GO:0045927 96 53 0,000 0,06078376 0,06755903 ! inner ear development GO:0048839 89 53 0,000 0,06078376 0,0675283 ! chromatin remodeling GO:0006338 122 53 0,000 0,06078376 0,06749761 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,06078376 0,06746694 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,06078376 0,0674363 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,06078376 0,06740569 ! cartilage development GO:0051216 99 53 0,000 0,06078376 0,06737511 ! synapse organization GO:0050808 102 53 0,000 0,06078376 0,06734455 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,06189523 0,0685449 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,06189523 0,06851384 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,06189523 0,06848281 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,06189523 0,06845181 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,06189523 0,06842084 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,06189523 0,06838989 ! membrane fusion GO:0006944 122 54 0,000 0,06189523 0,06835897 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,06189523 0,06832808 ! covalent chromatin modification GO:0016569 115 54 0,000 0,06189523 0,06829722 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,06189523 0,06826639 ! regulation of cell shape GO:0008360 142 54 0,000 0,06189523 0,06823558 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,06189523 0,0682048 ! RNA catabolic process GO:0006401 103 55 0,000 0,06300542 0,06939686 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,06300542 0,06936558 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,06300542 0,06933434 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,06300542 0,06930312 ! cell recognition GO:0008037 98 55 0,000 0,06300542 0,06927193 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,06300542 0,06924077 ! cell maturation GO:0048469 107 55 0,000 0,06300542 0,06920964 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,06300542 0,06917853 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,06300542 0,06914745 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,06411432 0,07033286 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,06411432 0,07030129 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,06411432 0,07026975 ! regulation of DNA replication GO:0006275 105 56 0,000 0,06411432 0,07023824 ! RNA elongation GO:0006354 90 56 0,000 0,06411432 0,07020676 ! chloride transport GO:0006821 102 57 0,000 0,06522194 0,07138763 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,06522194 0,07135566 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,06522194 0,07132372 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,06522194 0,07129181 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,06522194 0,07125992 ! heart morphogenesis GO:0003007 105 57 0,000 0,06522194 0,07122807 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,06522194 0,07119624 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,06522194 0,07116444 ! regulation of actin filament length GO:0030832 118 58 0,000 0,06632827 0,07233927 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,06632827 0,07230699 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,06632827 0,07227474 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,06632827 0,07224252 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,06632827 0,07221033 ! gastrulation GO:0007369 122 58 0,000 0,06632827 0,07217816 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,06632827 0,07214603 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,06632827 0,07211392 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,06632827 0,07208184 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,06632827 0,07204979 ! maintenance of location GO:0051235 124 58 0,000 0,06632827 0,07201777 ! nuclear export GO:0051168 110 59 0,000 0,06743334 0,07318509 ! establishment of organelle localization GO:0051656 122 59 0,000 0,06743334 0,07315259 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,06853712 0,07431699 ! lipid modification GO:0030258 112 60 0,000 0,06853712 0,07428402 ! DNA catabolic process GO:0006308 94 60 0,000 0,06853712 0,07425108 ! regulation of endocytosis GO:0030100 104 60 0,000 0,06853712 0,07421817 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,06853712 0,07418528 ! adult behavior GO:0030534 104 60 0,000 0,06853712 0,07415243 ! kidney development GO:0001822 133 60 0,000 0,06853712 0,0741196 ! positive regulation of secretion GO:0051047 110 61 0,000 0,06963963 0,07527859 ! regulation of cellular component size GO:0032535 125 61 0,000 0,06963963 0,0752453 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,06963963 0,07521203 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,06963963 0,0751788 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,06963963 0,07514559 ! regulation of heart contraction GO:0008016 123 61 0,000 0,06963963 0,07511241 ! camera-type eye development GO:0043010 126 61 0,000 0,06963963 0,07507927 ! proton transport GO:0015992 117 61 0,000 0,06963963 0,07504615 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,06963963 0,07501306 ! viral reproductive process GO:0022415 132 62 0,000 0,07074087 0,07616568 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,07074087 0,07613213 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,07074087 0,07609861 ! tRNA processing GO:0008033 102 62 0,000 0,07074087 0,07606511 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,07074087 0,07603165 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,07184083 0,07717992 ! regulation of mitosis GO:0007088 112 63 0,000 0,07184083 0,077146 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,07184083 0,0771121 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,07184083 0,07707824 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,07184083 0,0770444 ! hydrogen transport GO:0006818 121 64 0,000 0,07293952 0,07818835 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,07293952 0,07815406 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,07293952 0,07811979 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,07293952 0,07808556 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,07293952 0,07805136 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,07403694 0,079191 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,07403694 0,07915635 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,07403694 0,07912172 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,07403694 0,07908712 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,07403694 0,07905256 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,07403694 0,07901802 ! ear development GO:0043583 114 66 0,000 0,0751331 0,08015291 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,0751331 0,08011792 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,0751331 0,08008296 ! gonad development GO:0008406 115 66 0,000 0,0751331 0,08004804 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,0751331 0,08001315 ! activation of MAPK activity GO:0000187 124 67 0,000 0,07622798 0,08114378 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,07622798 0,08110843 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,07622798 0,08107312 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,07622798 0,08103784 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,07622798 0,08100259 ! secondary metabolic process GO:0019748 125 67 0,000 0,07622798 0,08096738 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,07622798 0,08093219 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,07732161 0,08205764 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,07732161 0,08202201 ! extracellular matrix organization GO:0030198 146 68 0,000 0,07732161 0,08198641 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,07732161 0,08195084 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,07732161 0,0819153 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,07732161 0,08187979 ! viral reproduction GO:0016032 142 68 0,000 0,07732161 0,08184432 ! regulation of lipase activity GO:0060191 137 68 0,000 0,07732161 0,08180887 ! adaptive immune response GO:0002250 126 68 0,000 0,07732161 0,08177346 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,07732161 0,08173807 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,07841396 0,08285697 ! lung development GO:0030324 165 69 0,000 0,07841396 0,08282115 ! urogenital system development GO:0001655 149 69 0,000 0,07841396 0,08278536 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,07841396 0,0827496 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,07841396 0,08271387 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,07841396 0,08267817 ! developmental maturation GO:0021700 128 69 0,000 0,07841396 0,0826425 ! single fertilization GO:0007338 83 69 0,000 0,07841396 0,08260686 ! cell redox homeostasis GO:0045454 114 70 0,000 0,07950506 0,0837202 ! germ cell development GO:0007281 133 70 0,000 0,07950506 0,08368413 ! activation of immune response GO:0002253 120 70 0,000 0,07950506 0,08364809 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,07950506 0,08361208 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,08059489 0,08472174 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,08059489 0,0846853 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,08059489 0,08464889 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,08059489 0,08461252 ! appendage morphogenesis GO:0035107 150 72 0,000 0,08168347 0,08571852 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,08168347 0,08568171 ! respiratory tube development GO:0030323 171 72 0,000 0,08168347 0,08564494 ! B cell activation GO:0042113 179 72 0,000 0,08168347 0,0856082 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,08168347 0,08557149 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,08168347 0,08553481 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,08168347 0,08549816 ! appendage development GO:0048736 151 73 0,000 0,08277079 0,08659916 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,08277079 0,08656208 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,08277079 0,08652504 ! regulation of immune effector process GO:0002697 156 73 0,000 0,08277079 0,08648804 ! acute inflammatory response GO:0002526 118 74 0,000 0,08385685 0,08758541 ! amino acid transport GO:0006865 148 74 0,000 0,08385685 0,08754798 ! regulation of caspase activity GO:0043281 136 74 0,000 0,08385685 0,08751058 ! respiratory system development GO:0060541 175 74 0,000 0,08385685 0,08747322 ! organelle localization GO:0051640 155 74 0,000 0,08385685 0,08743588 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,08494165 0,0885292 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,08494165 0,08849145 ! reproductive structure development GO:0048608 131 75 0,000 0,08494165 0,08845373 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,08494165 0,08841604 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,08494165 0,08837839 ! axon guidance GO:0007411 162 75 0,000 0,08494165 0,08834076 ! rhythmic process GO:0048511 142 75 0,000 0,08494165 0,08830317 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,0860252 0,08939156 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,0860252 0,08935356 ! learning or memory GO:0007611 161 76 0,000 0,0860252 0,08931558 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,0860252 0,08927764 ! regulation of blood pressure GO:0008217 134 76 0,000 0,0860252 0,08923973 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,0860252 0,08920185 ! amine catabolic process GO:0009310 136 77 0,000 0,0871075 0,09028579 ! neurotransmitter transport GO:0006836 142 77 0,000 0,0871075 0,09024751 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,0871075 0,09020925 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,0871075 0,09017102 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,0871075 0,09013283 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,0871075 0,09009467 ! regulation of catabolic process GO:0009894 173 77 0,000 0,0871075 0,09005655 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,08818854 0,09113562 ! antigen processing and presentation GO:0019882 117 78 0,000 0,08818854 0,09109709 ! fertilization GO:0009566 99 78 0,000 0,08818854 0,09105859 ! blood coagulation GO:0007596 151 79 0,000 0,08926834 0,09213458 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,08926834 0,09209567 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,08926834 0,0920568 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,08926834 0,09201796 ! protein oligomerization GO:0051259 149 79 0,000 0,08926834 0,09197915 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,08926834 0,09194037 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,09034689 0,09301199 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,09034689 0,09297281 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,09034689 0,09293366 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,09034689 0,09289455 ! meiosis GO:0007126 143 81 0,000 0,09142419 0,09396268 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,09142419 0,09392317 ! response to hypoxia GO:0001666 178 81 0,000 0,09142419 0,09388369 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,09142419 0,09384424 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,09250025 0,09490891 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,09250025 0,09486906 ! protein import into nucleus GO:0006606 174 82 0,000 0,09250025 0,09482925 ! meiotic cell cycle GO:0051321 144 82 0,000 0,09250025 0,09478947 ! exocytosis GO:0006887 153 83 0,000 0,09357506 0,09585068 ! response to drug GO:0042493 149 83 0,000 0,09357506 0,09581051 ! response to oxygen levels GO:0070482 183 83 0,000 0,09357506 0,09577037 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,09357506 0,09573026 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,09357506 0,09569019 ! nuclear import GO:0051170 177 83 0,000 0,09357506 0,09565016 ! inorganic anion transport GO:0015698 156 83 0,000 0,09357506 0,09561015 ! T cell activation GO:0042110 189 84 0,000 0,09464863 0,09666664 ! response to nutrient GO:0007584 135 84 0,000 0,09464863 0,09662624 ! digestion GO:0007586 130 84 0,000 0,09464863 0,09658588 ! hemostasis GO:0007599 165 85 0,000 0,09572096 0,09763937 ! negative regulation of transport GO:0051051 164 85 0,000 0,09572096 0,09759862 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,09572096 0,09755791 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,09572096 0,09751722 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,09572096 0,09747657 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,09572096 0,09743596 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,0978619 0,09957377 ! nucleosome assembly GO:0006334 126 87 0,000 0,0978619 0,09953231 ! regulation of protein transport GO:0051223 165 87 0,000 0,0978619 0,09949089 GO:0070201|regulation of establishment of protein localization, ! amine biosynthetic process GO:0009309 146 88 0,000 0,09893051 0,10053545 ! sensory perception of smell GO:0007608 117 88 0,000 0,09893051 0,10049365 ! chromatin assembly GO:0031497 128 88 0,000 0,09893051 0,10045188 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,09893051 0,10041015 ! regulation of DNA binding GO:0051101 167 89 0,000 0,09999789 0,10145134 ! tube morphogenesis GO:0035239 194 89 0,000 0,09999789 0,10140923 ! cellular defense response GO:0006968 123 89 0,000 0,09999789 0,10136715 ! protein localization in nucleus GO:0034504 192 89 0,000 0,09999789 0,10132511 ! regulation of neurological system process GO:0031644 175 89 0,000 0,09999789 0,1012831 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,10106403 0,10232052 ! gland development GO:0048732 220 91 0,000 0,10212894 0,10335584 ! defense response to bacterium GO:0042742 112 91 0,000 0,10212894 0,10331304 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,10319262 0,10434585 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,10319262 0,10430267 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,10425506 0,10533297 ! amine transport GO:0015837 181 93 0,000 0,10425506 0,10528943 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,10425506 0,10524592 ! vitamin metabolic process GO:0006766 153 93 0,000 0,10425506 0,10520245 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,10531628 0,10622943 ! female pregnancy GO:0007565 166 94 0,000 0,10531628 0,10618559 ! sterol metabolic process GO:0016125 166 94 0,000 0,10531628 0,10614178 ! regulation of membrane potential GO:0042391 179 94 0,000 0,10531628 0,10609801 ! regulation of defense response GO:0031347 171 95 0,000 0,10637628 0,1071217 ! nucleosome organization GO:0034728 143 95 0,000 0,10637628 0,10707756 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,10637628 0,10703346 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,10637628 0,1069894 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,10637628 0,10694537 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,10637628 0,10690137 ! sex differentiation GO:0007548 171 96 0,000 0,10743504 0,10792097 ! regulation of T cell activation GO:0050863 175 96 0,000 0,10743504 0,10787662 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,10849258 0,10889375 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,10849258 0,10884903 ! transcription initiation GO:0006352 171 97 0,000 0,10849258 0,10880434 ! regulation of protein localization GO:0032880 188 97 0,000 0,10849258 0,1087597 ! leukocyte differentiation GO:0002521 232 98 0,000 0,1095489 0,10977357 ! forebrain development GO:0030900 210 98 0,000 0,1095489 0,10972856 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,11165787 0,11179516 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,11165787 0,11174936 ! positive regulation of immune response GO:0050778 175 100 0,000 0,11165787 0,1117036 ! hormone metabolic process GO:0042445 171 100 0,000 0,11165787 0,11165787