pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/369-4-real-Desmedt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! substrate-bound cell migration, cell extension GO:0006930 5 5 2,000 4,095E-08 9,418E-05 ! substrate-bound cell migration GO:0006929 10 9 2,000 3,424E-07 3,938E-04 ! glycolysis GO:0006096 53 44 3,000 7,916E-07 6,069E-04 ! glucose catabolic process GO:0006007 66 54 3,000 1,823E-06 1,048E-03 ! hexose catabolic process GO:0019320 82 64 3,000 3,621E-06 1,666E-03 ! monosaccharide catabolic process GO:0046365 91 71 3,000 5,494E-06 2,106E-03 ! alcohol catabolic process GO:0046164 104 80 3,000 8,851E-06 2,908E-03 ! carbohydrate catabolic process GO:0016052 121 93 3,000 1,61E-05 4,628E-03 ! response to light stimulus GO:0009416 153 96 3,000 1,825E-05 4,665E-03 ! regulation of hormone biosynthetic process GO:0046885 7 5 1,000 2,649E-05 6,092E-03 ! embryonic hemopoiesis GO:0035162 10 5 1,000 2,649E-05 5,538E-03 ! positive regulation of glycolysis GO:0045821 11 5 1,000 2,649E-05 5,077E-03 ! positive regulation of chemokine production GO:0032722 7 5 1,000 2,649E-05 4,686E-03 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 3,969E-05 6,521E-03 ! photoreceptor cell development GO:0042461 10 6 1,000 3,969E-05 6,086E-03 GO:0046530|photoreceptor cell differentiation, ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 1,000 3,969E-05 5,706E-03 ! gas homeostasis GO:0033483 11 6 1,000 3,969E-05 5,37E-03 ! regulation of Rac protein signal transduction GO:0035020 8 6 1,000 3,969E-05 5,072E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 3,969E-05 4,805E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 4,844E-05 5,57E-03 ! induction of apoptosis by extracellular signals GO:0008624 74 44 2,000 5,192E-05 5,687E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 5,551E-05 5,803E-03 ! hemoglobin metabolic process GO:0020027 10 7 1,000 5,551E-05 5,551E-03 ! positive regulation of monooxygenase activity GO:0032770 11 7 1,000 5,551E-05 5,32E-03 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 1,000 5,551E-05 5,107E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 1,000 5,551E-05 4,911E-03 ! response to UV GO:0009411 75 46 2,000 5,938E-05 5,059E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 7,394E-05 6,074E-03 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 1,000 7,394E-05 5,864E-03 GO:0046579|positive regulation of Ras protein signal transduction, ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 7,394E-05 5,669E-03 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 1,000 7,394E-05 5,486E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 7,394E-05 5,314E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 8,101E-05 5,646E-03 ! cell projection assembly GO:0030031 76 53 2,000 9,093E-05 6,151E-03 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 9,497E-05 6,241E-03 ! regulation of glycolysis GO:0006110 15 9 1,000 9,497E-05 6,067E-03 ! regulation of hormone metabolic process GO:0032350 15 9 1,000 9,497E-05 5,903E-03 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 1,000 9,497E-05 5,748E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 1,000 9,497E-05 5,601E-03 ! embryonic placenta development GO:0001892 12 9 1,000 9,497E-05 5,461E-03 ! establishment of cell polarity GO:0030010 12 9 1,000 9,497E-05 5,327E-03 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,186E-04 6,494E-03 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 1,000 1,186E-04 6,343E-03 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 1,186E-04 6,199E-03 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 1,000 1,186E-04 6,061E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 1,186E-04 5,929E-03 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 1,448E-04 7,085E-03 ! Golgi vesicle budding GO:0048194 17 11 1,000 1,448E-04 6,938E-03 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 1,448E-04 6,796E-03 ! regulation of vascular endothelial growth factor production GO:0010574 19 11 1,000 1,448E-04 6,66E-03 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 1,736E-04 7,828E-03 ! heart looping GO:0001947 15 12 1,000 1,736E-04 7,677E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 1,736E-04 7,532E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! histone acetylation GO:0016573 23 12 1,000 1,736E-04 7,393E-03 ! peptidyl-lysine modification GO:0018205 18 12 1,000 1,736E-04 7,258E-03 ! axon guidance GO:0007411 99 66 2,000 1,751E-04 7,19E-03 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 2,049E-04 8,268E-03 ! regulation of chemokine production GO:0032642 17 13 1,000 2,049E-04 8,126E-03 ! induction of apoptosis via death domain receptors GO:0008625 15 13 1,000 2,049E-04 7,988E-03 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 2,049E-04 7,855E-03 ! response to hypoxia GO:0001666 132 72 2,000 2,266E-04 8,546E-03 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 2,388E-04 8,86E-03 ! muscle maintenance GO:0046716 19 14 1,000 2,388E-04 8,719E-03 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 1,000 2,388E-04 8,583E-03 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 2,388E-04 8,451E-03 ! response to oxygen levels GO:0070482 137 74 2,000 2,458E-04 8,566E-03 ! negative regulation of growth GO:0045926 123 75 2,000 2,558E-04 8,78E-03 ! positive regulation of oxidoreductase activity GO:0051353 21 15 1,000 2,753E-04 9,311E-03 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 3,143E-04 0,01047606 ! protein amino acid acetylation GO:0006473 28 16 1,000 3,143E-04 0,0103264 ! cellular response to unfolded protein GO:0034620 19 16 1,000 3,143E-04 0,01018096 GO:0030968|endoplasmic reticulum unfolded protein response, ! neural crest cell migration GO:0001755 24 16 1,000 3,143E-04 0,01003956 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 3,143E-04 9,902E-03 ! membrane budding GO:0006900 29 17 1,000 3,558E-04 0,01105926 ! cell-cell junction organization GO:0045216 25 17 1,000 3,558E-04 0,0109118 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 3,829E-04 0,01158758 ! positive regulation of angiogenesis GO:0045766 35 18 1,000 3,999E-04 0,01194463 ! visual learning GO:0008542 35 18 1,000 3,999E-04 0,01179149 ! interphase GO:0051325 159 88 2,000 4,097E-04 0,01192658 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 4,465E-04 0,01283605 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 1,000 4,465E-04 0,01267758 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 4,465E-04 0,01252297 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to lipopolysaccharide GO:0032496 26 19 1,000 4,465E-04 0,01237209 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 4,465E-04 0,01222481 ! positive regulation of B cell activation GO:0050871 31 20 1,000 4,956E-04 0,01340951 ! response to oxidative stress GO:0006979 141 94 2,000 4,971E-04 0,01329357 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 5,472E-04 0,01446544 ! protein amino acid acylation GO:0043543 37 21 1,000 5,472E-04 0,01430106 ! visual behavior GO:0007632 39 21 1,000 5,472E-04 0,01414037 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 5,472E-04 0,01398326 ! cell aging GO:0007569 32 21 1,000 5,472E-04 0,0138296 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 5,472E-04 0,01367928 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 5,472E-04 0,01353219 ! response to glucocorticoid stimulus GO:0051384 33 21 1,000 5,472E-04 0,01338823 ! Ras protein signal transduction GO:0007265 162 100 2,000 5,956E-04 0,01442044 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 6,013E-04 0,01440541 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 6,579E-04 0,01559865 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 6,579E-04 0,01543948 ! response to corticosteroid stimulus GO:0031960 36 23 1,000 6,579E-04 0,01528353 ! cellular response to oxidative stress GO:0034599 33 23 1,000 6,579E-04 0,01513069 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 6,579E-04 0,01498088 ! response to molecule of bacterial origin GO:0002237 30 23 1,000 6,579E-04 0,01483401 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 7,169E-04 0,01600897 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 7,169E-04 0,01585504 ! fat cell differentiation GO:0045444 37 24 1,000 7,169E-04 0,01570404 ! neural crest cell development GO:0014032 39 24 1,000 7,169E-04 0,01555589 GO:0014033|neural crest cell differentiation, ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 7,169E-04 0,01541051 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 7,785E-04 0,0165784 GO:0045936|negative regulation of phosphate metabolic process, ! iron ion homeostasis GO:0055072 39 25 1,000 7,785E-04 0,0164263 ! negative regulation of neuron apoptosis GO:0043524 42 27 1,000 9,089E-04 0,01900494 ! positive regulation of catabolic process GO:0009896 40 28 1,000 9,778E-04 0,02026163 ! placenta development GO:0001890 37 28 1,000 9,778E-04 0,02008072 ! regulation of B cell activation GO:0050864 42 28 1,000 9,778E-04 0,01990301 ! protein targeting to membrane GO:0006612 53 29 1,000 1,049E-03 0,02116802 ! eye morphogenesis GO:0048592 51 29 1,000 1,049E-03 0,02098395 ! collagen metabolic process GO:0032963 40 30 1,000 1,123E-03 0,02226609 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 1,199E-03 0,02357401 ! regulation of synaptic plasticity GO:0048167 52 32 1,000 1,278E-03 0,0249069 ! cell junction organization GO:0034330 63 33 1,000 1,359E-03 0,02626399 ! carbohydrate homeostasis GO:0033500 39 33 1,000 1,359E-03 0,02604512 GO:0042593|glucose homeostasis, ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 1,000 1,359E-03 0,02582987 ! establishment or maintenance of cell polarity GO:0007163 61 34 1,000 1,442E-03 0,02719133 ! embryonic organ development GO:0048568 45 34 1,000 1,442E-03 0,02697026 ! keratinocyte differentiation GO:0030216 47 35 1,000 1,528E-03 0,028345 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 1,528E-03 0,02811824 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! tissue remodeling GO:0048771 62 36 1,000 1,616E-03 0,02950564 ! learning GO:0007612 67 37 1,000 1,707E-03 0,0309143 ! striated muscle cell differentiation GO:0051146 54 38 1,000 1,8E-03 0,03234359 ! mesenchymal cell development GO:0014031 64 38 1,000 1,8E-03 0,03209287 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! multicellular organismal metabolic process GO:0044236 50 39 1,000 1,895E-03 0,03353294 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 1,000 1,895E-03 0,03327697 ! response to calcium ion GO:0051592 58 40 1,000 1,993E-03 0,03472734 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 1,993E-03 0,03446623 ! epidermal cell differentiation GO:0009913 53 40 1,000 1,993E-03 0,03420902 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 1,993E-03 0,03395562 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 2,3E-03 0,0389011 ! vesicle organization GO:0016050 79 43 1,000 2,3E-03 0,03861715 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 2,407E-03 0,04012169 ! positive regulation of cell cycle GO:0045787 77 45 1,000 2,517E-03 0,04164298 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 2,517E-03 0,04134553 ! histone modification GO:0016570 68 46 1,000 2,628E-03 0,04287428 ! covalent chromatin modification GO:0016569 75 47 1,000 2,742E-03 0,04441884 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 2,742E-03 0,04410822 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 1,000 2,742E-03 0,04380191 ! heart morphogenesis GO:0003007 65 48 1,000 2,859E-03 0,04534457 ! positive regulation of cytokine production GO:0001819 73 48 1,000 2,859E-03 0,04503399 ! regulation of angiogenesis GO:0045765 94 49 1,000 2,977E-03 0,04658312 ! cartilage development GO:0051216 70 49 1,000 2,977E-03 0,04626837 ! positive regulation of cell migration GO:0030335 92 51 1,000 3,221E-03 0,0497246 ! aging GO:0007568 79 52 1,000 3,347E-03 0,05131615 ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 3,604E-03 0,05490015 ! positive regulation of cell motion GO:0051272 99 56 1,000 3,871E-03 0,05857297 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 4,008E-03 0,06024434 ! negative regulation of kinase activity GO:0033673 100 58 1,000 4,146E-03 0,06192722 ! actin filament organization GO:0007015 95 59 1,000 4,288E-03 0,0636213 ! regulation of homeostatic process GO:0032844 105 60 1,000 4,431E-03 0,06532624 ! negative regulation of transferase activity GO:0051348 105 61 1,000 4,576E-03 0,06704174 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 4,576E-03 0,06661742 ! negative regulation of cell growth GO:0030308 106 62 1,000 4,724E-03 0,06833498 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 4,724E-03 0,06790789 ! negative regulation of cell size GO:0045792 108 64 1,000 5,026E-03 0,07179979 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 5,026E-03 0,07135658 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 5,18E-03 0,07309526 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 5,18E-03 0,07264956 ! protein oligomerization GO:0051259 100 65 1,000 5,18E-03 0,07220926 ! learning or memory GO:0007611 123 68 1,000 5,656E-03 0,0783654 ! activation of protein kinase activity GO:0032147 102 69 1,000 5,819E-03 0,08013927 ! positive regulation of ligase activity GO:0051351 99 69 1,000 5,819E-03 0,07966225 ! response to metal ion GO:0010038 103 70 1,000 5,984E-03 0,08143657 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 1,000 5,984E-03 0,08095753 ! eye development GO:0001654 111 70 1,000 5,984E-03 0,08048409 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 5,984E-03 0,08001616 ! regulation of catabolic process GO:0009894 106 70 1,000 5,984E-03 0,07955364 ! muscle cell differentiation GO:0042692 104 71 1,000 6,151E-03 0,08130578 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 6,151E-03 0,08084117 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 6,32E-03 0,08259385 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of synaptic transmission GO:0050804 109 72 1,000 6,32E-03 0,08212721 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 6,492E-03 0,08388034 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 6,665E-03 0,085641 ! response to inorganic substance GO:0010035 115 75 1,000 6,841E-03 0,08740897 ! regulation of ligase activity GO:0051340 114 75 1,000 6,841E-03 0,08692605 ! response to unfolded protein GO:0006986 99 76 1,000 7,018E-03 0,08869404 ! regulation of transmission of nerve impulse GO:0051969 116 77 1,000 7,198E-03 0,09046897 ! positive regulation of protein modification process GO:0031401 107 78 1,000 7,38E-03 0,09225065 ! cellular respiration GO:0045333 107 79 1,000 7,564E-03 0,09403888 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 7,75E-03 0,09583347 GO:0010498|proteasomal protein catabolic process, ! response to protein stimulus GO:0051789 111 81 1,000 7,938E-03 0,09763422 ! regulation of neurological system process GO:0031644 122 81 1,000 7,938E-03 0,09711489 ! positive regulation of cell activation GO:0050867 120 81 1,000 7,938E-03 0,09660106 GO:0002696|positive regulation of leukocyte activation, ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 8,268E-03 0,10008288 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 8,268E-03 0,09955888 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 8,268E-03 0,09904035 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 8,268E-03 0,09852719 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 8,268E-03 0,09801931 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 8,268E-03 0,09751665 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 8,268E-03 0,09701912 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 8,268E-03 0,09652663 ! sleep GO:0030431 11 5 0,000 8,268E-03 0,09603913 ! negative regulation of bone resorption GO:0045779 10 5 0,000 8,268E-03 0,09555652 ! nucleotide-sugar transport GO:0015780 8 5 0,000 8,268E-03 0,09507873 ! regulation of interferon-beta production GO:0032648 5 5 0,000 8,268E-03 0,09460571 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 8,268E-03 0,09413736 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 8,268E-03 0,09367363 ! tongue development GO:0043586 6 5 0,000 8,268E-03 0,09321445 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 8,268E-03 0,09275974 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 8,268E-03 0,09230945 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 8,268E-03 0,09186351 ! cobalt ion transport GO:0006824 9 5 0,000 8,268E-03 0,09142186 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 8,268E-03 0,09098444 ! SMAD protein complex assembly GO:0007183 9 5 0,000 8,268E-03 0,09055118 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 8,268E-03 0,09012202 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 8,268E-03 0,08969692 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 8,268E-03 0,08927581 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 8,268E-03 0,08885863 ! embryonic camera-type eye development GO:0031076 8 5 0,000 8,268E-03 0,08844533 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 8,268E-03 0,08803587 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 8,268E-03 0,08763017 ! adaptation of signaling pathway GO:0022401 7 5 0,000 8,268E-03 0,0872282 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 8,268E-03 0,08682989 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 8,268E-03 0,08643521 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 8,268E-03 0,0860441 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 8,268E-03 0,08565652 ! positive regulation of histone modification GO:0031058 5 5 0,000 8,268E-03 0,08527241 ! malate metabolic process GO:0006108 7 5 0,000 8,268E-03 0,08489173 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 8,268E-03 0,08451443 ! behavioral response to pain GO:0048266 7 5 0,000 8,268E-03 0,08414047 ! clathrin coat assembly GO:0048268 11 5 0,000 8,268E-03 0,08376981 ! phototransduction, visible light GO:0007603 6 5 0,000 8,268E-03 0,0834024 ! regulation of dopamine uptake GO:0051584 9 5 0,000 8,268E-03 0,0830382 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 8,268E-03 0,08267716 ! mating behavior GO:0007617 6 5 0,000 8,268E-03 0,08231925 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 8,268E-03 0,08196443 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 8,268E-03 0,08161265 ! rhythmic behavior GO:0007622 12 5 0,000 8,268E-03 0,08126388 ! copulation GO:0007620 7 5 0,000 8,268E-03 0,08091807 ! glial cell fate commitment GO:0021781 12 5 0,000 8,268E-03 0,0805752 ! protein maturation by protein folding GO:0022417 12 5 0,000 8,268E-03 0,08023522 ! regulation of potassium ion transport GO:0043266 9 5 0,000 8,268E-03 0,0798981 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 8,268E-03 0,07956379 ! apoptotic cell clearance GO:0043277 13 5 0,000 8,268E-03 0,07923228 ! lipoprotein particle clearance GO:0034381 9 5 0,000 8,268E-03 0,07890351 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 8,268E-03 0,07857747 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 8,268E-03 0,0782541 ! response to protozoan GO:0001562 9 5 0,000 8,268E-03 0,07793339 ! lymph vessel development GO:0001945 7 5 0,000 8,268E-03 0,07761529 ! endochondral ossification GO:0001958 12 5 0,000 8,268E-03 0,07729978 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 8,268E-03 0,07698683 ! parathyroid gland development GO:0060017 8 5 0,000 8,268E-03 0,0766764 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 8,268E-03 0,07636846 ! anagen GO:0042640 6 5 0,000 8,268E-03 0,07606299 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 8,268E-03 0,07575995 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 8,268E-03 0,07545931 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 8,268E-03 0,07516106 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 8,268E-03 0,07486515 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 8,268E-03 0,07457156 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 8,268E-03 0,07428026 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 8,268E-03 0,07399123 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 8,268E-03 0,07370445 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 8,268E-03 0,07341987 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 8,268E-03 0,07313749 ! cardiac muscle fiber development GO:0048739 7 5 0,000 8,268E-03 0,07285727 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 8,268E-03 0,07257919 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 8,268E-03 0,07230322 ! neutrophil mediated immunity GO:0002446 6 5 0,000 8,268E-03 0,07202934 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 8,268E-03 0,07175754 ! ovulation GO:0030728 6 5 0,000 8,268E-03 0,07148777 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 8,268E-03 0,07122003 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 8,268E-03 0,07095428 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 8,268E-03 0,07069051 ! response to pH GO:0009268 9 5 0,000 8,268E-03 0,07042869 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 8,268E-03 0,07016881 ! proline biosynthetic process GO:0006561 6 5 0,000 8,268E-03 0,06991083 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 8,268E-03 0,06965475 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 8,268E-03 0,06940054 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 8,268E-03 0,06914817 ! polyol catabolic process GO:0046174 7 5 0,000 8,268E-03 0,06889763 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 8,268E-03 0,06864891 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 8,268E-03 0,06840197 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 8,268E-03 0,0681568 ! sister chromatid cohesion GO:0007062 9 5 0,000 8,268E-03 0,06791338 ! nerve growth factor processing GO:0032455 7 5 0,000 8,268E-03 0,0676717 ! urea metabolic process GO:0019627 6 5 0,000 8,268E-03 0,06743173 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 8,268E-03 0,06719345 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 8,268E-03 0,06695686 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 8,268E-03 0,06672192 ! neutrophil activation GO:0042119 5 5 0,000 8,268E-03 0,06648863 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 8,268E-03 0,06625696 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 8,268E-03 0,0660269 ! response to food GO:0032094 5 5 0,000 8,268E-03 0,06579843 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 8,268E-03 0,06557154 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 8,268E-03 0,06534621 ! paraxial mesoderm development GO:0048339 9 5 0,000 8,268E-03 0,06512242 ! forebrain neuron development GO:0021884 7 5 0,000 8,268E-03 0,06490016 ! melanosome organization GO:0032438 7 5 0,000 8,268E-03 0,06467941 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 8,268E-03 0,06446016 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 8,268E-03 0,06424239 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 8,268E-03 0,06402608 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 8,268E-03 0,06381123 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 8,268E-03 0,06359782 ! nucleoside transport GO:0015858 6 5 0,000 8,268E-03 0,06338582 ! nucleoside salvage GO:0043174 7 5 0,000 8,268E-03 0,06317524 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 8,268E-03 0,06296605 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 8,268E-03 0,06275824 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 8,268E-03 0,0625518 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 8,268E-03 0,06234671 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 8,268E-03 0,06214296 ! early endosome to late endosome transport GO:0045022 11 5 0,000 8,268E-03 0,06194054 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 8,268E-03 0,06173944 ! depyrimidination GO:0045008 8 5 0,000 8,268E-03 0,06153963 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 8,268E-03 0,06134112 ! 5S class rRNA transcription GO:0042791 8 5 0,000 8,268E-03 0,06114388 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 8,268E-03 0,06094791 ! regulation of centrosome cycle GO:0046605 7 5 0,000 8,268E-03 0,06075319 ! neuronal ion channel clustering GO:0045161 7 5 0,000 8,268E-03 0,0605597 ! sodium ion homeostasis GO:0055078 6 5 0,000 8,268E-03 0,06036745 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 8,268E-03 0,06017641 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 8,268E-03 0,05998658 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 8,268E-03 0,05979795 ! monocyte differentiation GO:0030224 8 5 0,000 8,268E-03 0,05961049 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 8,268E-03 0,05942421 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 8,268E-03 0,05923909 ! centrosome duplication GO:0051298 5 5 0,000 8,268E-03 0,05905511 ! response to UV-C GO:0010225 6 5 0,000 8,268E-03 0,05887228 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 8,268E-03 0,05869058 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 8,268E-03 0,05850999 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 8,268E-03 0,05833051 ! regulation of dendrite development GO:0050773 12 5 0,000 8,268E-03 0,05815213 ! peptidyl-arginine modification GO:0018195 7 5 0,000 8,268E-03 0,05797484 ! positive regulation of organ growth GO:0046622 6 5 0,000 8,268E-03 0,05779862 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 8,268E-03 0,05762348 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 8,268E-03 0,05744939 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 8,268E-03 0,05727635 ! regulation of dopamine secretion GO:0014059 12 5 0,000 8,268E-03 0,05710435 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 8,268E-03 0,05693337 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 8,268E-03 0,05676342 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 8,268E-03 0,05659449 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 8,268E-03 0,05642655 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 8,268E-03 0,05625961 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 8,268E-03 0,05609365 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 8,268E-03 0,05592867 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 8,268E-03 0,05576465 ! neural tube patterning GO:0021532 6 5 0,000 8,268E-03 0,0556016 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 8,268E-03 0,0554395 ! histone demethylation GO:0016577 9 5 0,000 8,268E-03 0,05527833 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 8,268E-03 0,05511811 ! regulation of sterol transport GO:0032371 7 5 0,000 8,268E-03 0,05495881 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 8,268E-03 0,05480042 ! establishment of planar polarity GO:0001736 6 5 0,000 8,268E-03 0,05464295 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 8,268E-03 0,05448638 ! muscle cell proliferation GO:0033002 8 5 0,000 8,268E-03 0,05433071 ! transcription termination GO:0006353 8 5 0,000 8,268E-03 0,05417592 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 8,268E-03 0,05402201 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 8,268E-03 0,05386897 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 8,268E-03 0,0537168 ! regulation of respiratory burst GO:0060263 8 5 0,000 8,268E-03 0,05356548 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 8,268E-03 0,05341502 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 8,268E-03 0,0532654 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 8,268E-03 0,05311661 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 8,268E-03 0,05296865 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 8,268E-03 0,05282152 ! apical protein localization GO:0045176 6 5 0,000 8,268E-03 0,0526752 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 8,268E-03 0,05252969 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 8,268E-03 0,05238498 ! galactolipid metabolic process GO:0019374 7 5 0,000 8,268E-03 0,05224106 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 8,268E-03 0,05209794 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 8,268E-03 0,05195559 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 8,268E-03 0,05181402 ! triglyceride catabolic process GO:0019433 6 5 0,000 8,268E-03 0,05167323 ! glial cell migration GO:0008347 10 5 0,000 8,268E-03 0,05153319 ! determination of adult lifespan GO:0008340 8 5 0,000 8,268E-03 0,05139391 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 8,268E-03 0,05125538 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 8,268E-03 0,0511176 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 8,268E-03 0,05098055 ! somatic stem cell maintenance GO:0035019 13 5 0,000 8,268E-03 0,05084424 ! cerebellar cortex formation GO:0021697 6 5 0,000 8,268E-03 0,05070866 ! neural plate development GO:0001840 6 5 0,000 8,268E-03 0,0505738 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 8,268E-03 0,05043965 ! regulation of sensory perception GO:0051931 6 5 0,000 8,268E-03 0,05030621 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 8,268E-03 0,05017347 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 8,268E-03 0,05004144 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 8,268E-03 0,0499101 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 8,268E-03 0,04977944 ! sensory cilium assembly GO:0035058 6 5 0,000 8,268E-03 0,04964947 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 8,268E-03 0,04952017 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 8,268E-03 0,04939155 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 8,268E-03 0,04926359 ! spindle assembly GO:0051225 5 5 0,000 8,268E-03 0,0491363 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 8,268E-03 0,04900966 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 8,268E-03 0,04888367 ! protein amino acid prenylation GO:0018346 9 5 0,000 8,268E-03 0,04875833 ! organ regeneration GO:0031100 7 5 0,000 8,268E-03 0,04863362 ! NAD biosynthetic process GO:0009435 7 5 0,000 8,268E-03 0,04850956 ! carnitine metabolic process GO:0009437 5 5 0,000 8,268E-03 0,04838612 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 8,268E-03 0,04826332 ! cellular anion homeostasis GO:0030002 6 5 0,000 8,268E-03 0,04814113 GO:0055081|anion homeostasis, ! Golgi vesicle transport GO:0048193 138 85 1,000 8,711E-03 0,05059349 ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 8,711E-03 0,05046605 ! cell cycle arrest GO:0007050 150 86 1,000 8,909E-03 0,05148512 ! anatomical structure homeostasis GO:0060249 136 88 1,000 9,312E-03 0,053677 ! tRNA transcription GO:0009304 11 6 0,000 9,913E-03 0,0570016 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 9,913E-03 0,05685945 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 9,913E-03 0,05671801 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 9,913E-03 0,05657727 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 9,913E-03 0,05643722 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 9,913E-03 0,05629787 ! regulation of helicase activity GO:0051095 11 6 0,000 9,913E-03 0,05615921 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 9,913E-03 0,05602122 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 9,913E-03 0,05588392 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 9,913E-03 0,05574728 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 9,913E-03 0,05561131 ! positive regulation of axon extension GO:0045773 8 6 0,000 9,913E-03 0,05547601 ! prostate gland development GO:0030850 9 6 0,000 9,913E-03 0,05534135 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 9,913E-03 0,05520736 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 9,913E-03 0,05507401 ! forebrain neuron differentiation GO:0021879 9 6 0,000 9,913E-03 0,0549413 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 9,913E-03 0,05480923 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 9,913E-03 0,05467779 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 9,913E-03 0,05454698 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 9,913E-03 0,0544168 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 9,913E-03 0,05428723 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 9,913E-03 0,05415829 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 9,913E-03 0,05402995 ! neuron adhesion GO:0007158 9 6 0,000 9,913E-03 0,05390222 ! establishment of tissue polarity GO:0007164 7 6 0,000 9,913E-03 0,05377509 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 9,913E-03 0,05364856 ! signal peptide processing GO:0006465 8 6 0,000 9,913E-03 0,05352262 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 9,913E-03 0,05339728 ! mRNA stabilization GO:0048255 15 6 0,000 9,913E-03 0,05327252 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 9,913E-03 0,05314834 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 9,913E-03 0,05302474 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 9,913E-03 0,05290171 ! opsonization GO:0008228 8 6 0,000 9,913E-03 0,05277926 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 9,913E-03 0,05265736 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 9,913E-03 0,05253603 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 9,913E-03 0,05241526 ! protein amino acid dealkylation GO:0008214 11 6 0,000 9,913E-03 0,05229504 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 9,913E-03 0,05217537 ! regulation of odontogenesis GO:0042481 8 6 0,000 9,913E-03 0,05205625 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 9,913E-03 0,05193767 ! mechanosensory behavior GO:0007638 8 6 0,000 9,913E-03 0,05181963 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 9,913E-03 0,05170213 ! negative regulation of endocytosis GO:0045806 8 6 0,000 9,913E-03 0,05158515 ! response to interferon-gamma GO:0034341 12 6 0,000 9,913E-03 0,05146871 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 9,913E-03 0,05135279 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 9,913E-03 0,05123739 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 9,913E-03 0,05112251 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 9,913E-03 0,05100814 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 9,913E-03 0,05089428 ! cGMP-mediated signaling GO:0019934 10 6 0,000 9,913E-03 0,05078093 ! activation of MAPKKK activity GO:0000185 10 6 0,000 9,913E-03 0,05066808 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 9,913E-03 0,05055574 ! thymic T cell selection GO:0045061 12 6 0,000 9,913E-03 0,05044389 ! protein lipoylation GO:0009249 10 6 0,000 9,913E-03 0,05033253 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 9,913E-03 0,05022167 ! pigment granule organization GO:0048753 11 6 0,000 9,913E-03 0,05011129 ! drug transport GO:0015893 6 6 0,000 9,913E-03 0,0500014 ! cysteine metabolic process GO:0006534 7 6 0,000 9,913E-03 0,04989199 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 9,913E-03 0,04978305 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 9,913E-03 0,04967459 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 9,913E-03 0,0495666 ! histidine metabolic process GO:0006547 6 6 0,000 9,913E-03 0,04945909 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 9,913E-03 0,04935203 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 9,913E-03 0,04924544 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 9,913E-03 0,04913931 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 9,913E-03 0,04903363 ! adenohypophysis development GO:0021984 10 6 0,000 9,913E-03 0,04892841 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 9,913E-03 0,04882364 ! hyperosmotic response GO:0006972 8 6 0,000 9,913E-03 0,04871931 ! microtubule nucleation GO:0007020 10 6 0,000 9,913E-03 0,04861543 ! ER overload response GO:0006983 7 6 0,000 9,913E-03 0,048512 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 9,913E-03 0,048409 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 9,913E-03 0,04830644 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 9,913E-03 0,04820431 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 9,913E-03 0,04810261 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 9,913E-03 0,04800134 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 9,913E-03 0,0479005 ! response to dietary excess GO:0002021 7 6 0,000 9,913E-03 0,04780008 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 9,913E-03 0,04770008 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 9,913E-03 0,0476005 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 9,913E-03 0,04750133 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 9,913E-03 0,04740257 ! glycerol ether catabolic process GO:0044269 8 6 0,000 9,913E-03 0,04730423 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 9,913E-03 0,04720629 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 9,913E-03 0,04710876 ! neuron apoptosis GO:0051402 8 6 0,000 9,913E-03 0,04701163 ! organic alcohol transport GO:0015850 9 6 0,000 9,913E-03 0,04691489 ! T cell mediated immunity GO:0002456 12 6 0,000 9,913E-03 0,04681856 ! male sex determination GO:0030238 9 6 0,000 9,913E-03 0,04672262 ! carnitine transport GO:0015879 8 6 0,000 9,913E-03 0,04662707 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 9,913E-03 0,04653191 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 9,913E-03 0,04643714 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 9,913E-03 0,04634276 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 9,913E-03 0,04624876 ! positive regulation of exocytosis GO:0045921 6 6 0,000 9,913E-03 0,04615514 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 9,913E-03 0,0460619 ! parturition GO:0007567 12 6 0,000 9,913E-03 0,04596903 ! negative regulation of translational initiation GO:0045947 7 6 0,000 9,913E-03 0,04587654 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 9,913E-03 0,04578441 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 9,913E-03 0,04569266 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 9,913E-03 0,04560128 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 9,913E-03 0,04551026 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 9,913E-03 0,0454196 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 9,913E-03 0,0453293 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 9,913E-03 0,04523936 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 9,913E-03 0,04514978 ! macrophage differentiation GO:0030225 10 6 0,000 9,913E-03 0,04506055 ! astrocyte development GO:0014002 14 6 0,000 9,913E-03 0,04497167 ! hyaluronan metabolic process GO:0030212 6 6 0,000 9,913E-03 0,04488315 ! purine base biosynthetic process GO:0009113 14 6 0,000 9,913E-03 0,04479497 ! interaction with symbiont GO:0051702 8 6 0,000 9,913E-03 0,04470713 ! anterograde axon cargo transport GO:0008089 8 6 0,000 9,913E-03 0,04461964 ! skeletal muscle contraction GO:0003009 6 6 0,000 9,913E-03 0,0445325 ! eating behavior GO:0042755 6 6 0,000 9,913E-03 0,04444569 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 9,913E-03 0,04435922 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 9,913E-03 0,04427308 ! response to copper ion GO:0046688 9 6 0,000 9,913E-03 0,04418728 ! DNA topological change GO:0006265 8 6 0,000 9,913E-03 0,04410181 ! response to exogenous dsRNA GO:0043330 8 6 0,000 9,913E-03 0,04401668 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 9,913E-03 0,04393187 ! establishment of melanosome localization GO:0032401 9 6 0,000 9,913E-03 0,04384738 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 9,913E-03 0,04376322 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 9,913E-03 0,04367938 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 9,913E-03 0,04359587 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 9,913E-03 0,04351267 ! nucleoside catabolic process GO:0009164 6 6 0,000 9,913E-03 0,04342979 ! hair follicle maturation GO:0048820 7 6 0,000 9,913E-03 0,04334722 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 9,913E-03 0,04326497 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 9,913E-03 0,04318303 ! Schwann cell development GO:0014044 14 6 0,000 9,913E-03 0,0431014 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 9,913E-03 0,04302007 ! dendrite morphogenesis GO:0048813 9 6 0,000 9,913E-03 0,04293905 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 9,913E-03 0,04285834 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 9,913E-03 0,04277793 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 9,913E-03 0,04269782 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 9,913E-03 0,04261802 ! histone ubiquitination GO:0016574 7 6 0,000 9,913E-03 0,0425385 ! regulation of meiosis GO:0040020 10 6 0,000 9,913E-03 0,04245929 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 9,913E-03 0,04238037 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 9,913E-03 0,04230174 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 9,913E-03 0,0422234 ! regulation of mast cell activation GO:0033003 6 6 0,000 9,913E-03 0,04214536 ! membrane to membrane docking GO:0022614 12 6 0,000 9,913E-03 0,0420676 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 9,913E-03 0,04199013 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 9,913E-03 0,04191294 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 9,913E-03 0,04183603 ! receptor internalization GO:0031623 9 6 0,000 9,913E-03 0,04175941 ! neutrophil homeostasis GO:0001780 6 6 0,000 9,913E-03 0,04168307 ! coenzyme A metabolic process GO:0015936 9 6 0,000 9,913E-03 0,041607 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 9,913E-03 0,04153122 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 9,913E-03 0,04145571 ! protein deubiquitination GO:0016579 8 6 0,000 9,913E-03 0,04138047 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 9,913E-03 0,0413055 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 9,913E-03 0,04123081 ! peptidyl-histidine modification GO:0018202 9 6 0,000 9,913E-03 0,04115639 ! axonal fasciculation GO:0007413 9 6 0,000 9,913E-03 0,04108223 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 9,913E-03 0,04100834 ! thiamin metabolic process GO:0006772 6 6 0,000 9,913E-03 0,04093472 ! midbrain development GO:0030901 6 6 0,000 9,913E-03 0,04086136 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 9,913E-03 0,04078826 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 9,913E-03 0,04071543 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 9,913E-03 0,04064285 ! progesterone metabolic process GO:0042448 8 6 0,000 9,913E-03 0,04057053 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 9,913E-03 0,04049847 ! glycolipid catabolic process GO:0019377 13 6 0,000 9,913E-03 0,04042666 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 9,913E-03 0,04035511 ! positive regulation of glucose import GO:0046326 6 6 0,000 9,913E-03 0,04028381 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 9,913E-03 0,04021277 ! adult feeding behavior GO:0008343 6 6 0,000 9,913E-03 0,04014197 ! blastocyst growth GO:0001832 15 6 0,000 9,913E-03 0,04007142 ! pigment granule transport GO:0051904 12 6 0,000 9,913E-03 0,04000112 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 9,913E-03 0,03993107 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 9,913E-03 0,03986126 ! catecholamine transport GO:0051937 7 6 0,000 9,913E-03 0,03979169 ! organ or tissue specific immune response GO:0002251 7 6 0,000 9,913E-03 0,03972237 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 9,913E-03 0,03965328 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 9,913E-03 0,03958444 ! negative regulation of B cell activation GO:0050869 9 6 0,000 9,913E-03 0,03951584 ! protein prenylation GO:0018342 10 6 0,000 9,913E-03 0,03944747 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 9,913E-03 0,03937934 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 9,913E-03 0,03931145 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 9,913E-03 0,03924378 ! positive regulation of coagulation GO:0050820 11 6 0,000 9,913E-03 0,03917635 ! peptidyl-amino acid modification GO:0018193 147 93 1,000 0,01035338 0,04084525 ! in utero embryonic development GO:0001701 147 96 1,000 0,01100208 0,04333012 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,01122223 0,0441216 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01155629 0,04535745 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01155629 0,04528018 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01155629 0,04520317 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01155629 0,04512643 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01155629 0,04504994 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01155629 0,04497371 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01155629 0,04489775 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01155629 0,04482203 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01155629 0,04474657 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01155629 0,04467137 ! reproductive behavior GO:0019098 12 7 0,000 0,01155629 0,04459642 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01155629 0,04452172 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01155629 0,04444727 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01155629 0,04437306 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01155629 0,04429911 ! oligopeptide transport GO:0006857 11 7 0,000 0,01155629 0,0442254 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01155629 0,04415194 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01155629 0,04407872 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,01155629 0,04400574 ! RNA methylation GO:0001510 11 7 0,000 0,01155629 0,043933 ! pericardium development GO:0060039 8 7 0,000 0,01155629 0,0438605 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01155629 0,04378825 ! fibril organization GO:0043206 13 7 0,000 0,01155629 0,04371623 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01155629 0,04364444 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01155629 0,04357289 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01155629 0,04350158 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01155629 0,0434305 ! lipoprotein transport GO:0042953 9 7 0,000 0,01155629 0,04335965 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01155629 0,04328903 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01155629 0,04321864 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01155629 0,04314848 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01155629 0,04307855 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01155629 0,04300884 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01155629 0,04293936 ! chemosensory behavior GO:0007635 9 7 0,000 0,01155629 0,04287011 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01155629 0,04280107 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01155629 0,04273226 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01155629 0,04266367 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01155629 0,0425953 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01155629 0,04252714 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01155629 0,04245921 ! reflex GO:0060004 12 7 0,000 0,01155629 0,04239149 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01155629 0,04232399 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01155629 0,0422567 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01155629 0,04218963 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01155629 0,04212277 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01155629 0,04205612 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01155629 0,04198968 ! spinal cord patterning GO:0021511 7 7 0,000 0,01155629 0,04192345 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01155629 0,04185743 ! adrenal gland development GO:0030325 17 7 0,000 0,01155629 0,04179161 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01155629 0,04172601 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01155629 0,0416606 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01155629 0,04159541 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01155629 0,04153041 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01155629 0,04146562 ! endosome organization GO:0007032 10 7 0,000 0,01155629 0,04140104 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01155629 0,04133665 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01155629 0,04127246 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01155629 0,04120847 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01155629 0,04114468 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01155629 0,04108109 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01155629 0,04101769 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01155629 0,04095449 ! galactose metabolic process GO:0006012 10 7 0,000 0,01155629 0,04089148 ! vesicle fusion GO:0006906 15 7 0,000 0,01155629 0,04082867 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01155629 0,04076605 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01155629 0,04070362 ! organ growth GO:0035265 11 7 0,000 0,01155629 0,04064138 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01155629 0,04057934 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01155629 0,04051748 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01155629 0,04045581 ! retinol metabolic process GO:0042572 9 7 0,000 0,01155629 0,04039432 ! behavioral fear response GO:0001662 13 7 0,000 0,01155629 0,04033303 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01155629 0,04027192 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01155629 0,04021099 ! rRNA modification GO:0000154 12 7 0,000 0,01155629 0,04015025 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01155629 0,04008969 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01155629 0,04002932 ! response to UV-B GO:0010224 11 7 0,000 0,01155629 0,03996912 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01155629 0,03990911 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01155629 0,03984927 ! intermediate filament organization GO:0045109 11 7 0,000 0,01155629 0,03978962 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01155629 0,03973014 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01155629 0,03967084 ! fibrinolysis GO:0042730 9 7 0,000 0,01155629 0,03961172 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01155629 0,03955278 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01155629 0,039494 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01155629 0,03943541 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01155629 0,03937699 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01155629 0,03931874 ! response to tropane GO:0014073 13 7 0,000 0,01155629 0,03926066 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01155629 0,03920275 ! melanosome localization GO:0032400 10 7 0,000 0,01155629 0,03914502 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01155629 0,03908745 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01155629 0,03903005 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01155629 0,03897282 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01155629 0,03891576 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01155629 0,03885887 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01155629 0,03880214 ! mast cell activation GO:0045576 9 7 0,000 0,01155629 0,03874558 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01155629 0,03868918 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,01155629 0,03863294 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01155629 0,03857687 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01155629 0,03852096 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01155629 0,03846522 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01155629 0,03840963 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01155629 0,03835421 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01155629 0,03829894 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01155629 0,03824383 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01155629 0,03818889 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01155629 0,0381341 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01155629 0,03807946 ! response to tumor cell GO:0002347 12 7 0,000 0,01155629 0,03802499 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01155629 0,03797066 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01155629 0,0379165 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01155629 0,03786249 ! diuresis GO:0030146 12 7 0,000 0,01155629 0,03780863 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01155629 0,03775492 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01155629 0,03770137 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01155629 0,03764797 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01155629 0,03759472 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01155629 0,03754162 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01155629 0,03748867 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01155629 0,03743587 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01155629 0,03738321 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01155629 0,03733071 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01155629 0,03727835 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01155629 0,03722614 ! lymph node development GO:0048535 9 7 0,000 0,01155629 0,03717408 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01155629 0,03712216 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01155629 0,03707038 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01155629 0,03701875 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01155629 0,03696727 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01155629 0,03691592 ! ATP catabolic process GO:0006200 10 7 0,000 0,01155629 0,03686472 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01155629 0,03681366 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01155629 0,03676275 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01155629 0,03671197 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01155629 0,03666133 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01155629 0,03661083 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01155629 0,03656047 ! muscle adaptation GO:0043500 12 7 0,000 0,01155629 0,03651025 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01155629 0,03646017 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01155629 0,03641023 ! retina homeostasis GO:0001895 9 7 0,000 0,01155629 0,03636042 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01155629 0,03631074 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01155629 0,03626121 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01155629 0,03621181 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01155629 0,03616254 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01155629 0,0361134 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01155629 0,0360644 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01155629 0,03601554 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01319663 0,04107204 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01319663 0,04101654 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,01319663 0,04096118 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01319663 0,04090598 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01319663 0,04085093 ! associative learning GO:0008306 15 8 0,000 0,01319663 0,04079602 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01319663 0,04074126 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01319663 0,04068665 ! phosphate transport GO:0006817 10 8 0,000 0,01319663 0,04063218 ! N-glycan processing GO:0006491 12 8 0,000 0,01319663 0,04057786 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01319663 0,04052368 ! UTP metabolic process GO:0046051 8 8 0,000 0,01319663 0,04046965 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01319663 0,04041576 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01319663 0,04036202 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01319663 0,04030842 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01319663 0,04025496 ! succinate metabolic process GO:0006105 14 8 0,000 0,01319663 0,04020164 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01319663 0,04014846 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01319663 0,04009543 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01319663 0,04004253 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01319663 0,03998977 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01319663 0,03993715 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01319663 0,03988467 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01319663 0,03983233 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01319663 0,03978013 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01319663 0,03972806 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01319663 0,03967613 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01319663 0,03962433 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01319663 0,03957267 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01319663 0,03952114 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01319663 0,03946975 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01319663 0,03941849 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01319663 0,03936736 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01319663 0,03931637 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01319663 0,03926551 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01319663 0,03921478 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01319663 0,03916418 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01319663 0,03911371 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01319663 0,03906337 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01319663 0,03901316 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01319663 0,03896308 ! melanin metabolic process GO:0006582 12 8 0,000 0,01319663 0,03891313 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01319663 0,0388633 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01319663 0,0388136 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01319663 0,03876403 ! macrophage activation GO:0042116 12 8 0,000 0,01319663 0,03871459 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01319663 0,03866527 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01319663 0,03861608 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01319663 0,03856701 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01319663 0,03851807 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01319663 0,03846925 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01319663 0,03842055 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01319663 0,03837198 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01319663 0,03832353 ! ruffle organization GO:0031529 11 8 0,000 0,01319663 0,0382752 ! osteoblast development GO:0002076 13 8 0,000 0,01319663 0,038227 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01319663 0,03817892 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01319663 0,03813095 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01319663 0,03808311 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01319663 0,03803539 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01319663 0,03798778 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01319663 0,0379403 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01319663 0,03789293 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01319663 0,03784568 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01319663 0,03779855 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01319663 0,03775154 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01319663 0,03770464 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01319663 0,03765786 ! segment specification GO:0007379 10 8 0,000 0,01319663 0,0376112 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01319663 0,03756465 ! cellular extravasation GO:0045123 11 8 0,000 0,01319663 0,03751822 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01319663 0,0374719 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01319663 0,03742569 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01319663 0,0373796 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01319663 0,03733363 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01319663 0,03728776 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01319663 0,03724201 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01319663 0,03719637 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01319663 0,03715084 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01319663 0,03710542 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01319663 0,03706012 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01319663 0,03701492 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01319663 0,03696984 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01319663 0,03692486 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01319663 0,03688 ! icosanoid secretion GO:0032309 12 8 0,000 0,01319663 0,03683524 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01319663 0,03679059 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01319663 0,03674605 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01319663 0,03670162 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01319663 0,03665729 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01319663 0,03661307 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01319663 0,03656896 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01319663 0,03652495 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01319663 0,03648105 ! sterol catabolic process GO:0016127 9 8 0,000 0,01319663 0,03643726 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01319663 0,03639357 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01319663 0,03634999 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01319663 0,0363065 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01319663 0,03626313 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01319663 0,03621985 ! prophase GO:0051324 11 8 0,000 0,01319663 0,03617668 ! S phase GO:0051320 8 8 0,000 0,01319663 0,03613362 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01319663 0,03609065 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01319663 0,03604779 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01319663 0,03600503 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01319663 0,03596237 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01319663 0,03591981 ! hormone catabolic process GO:0042447 13 8 0,000 0,01319663 0,03587735 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01319663 0,03583499 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01319663 0,03579273 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01319663 0,03575057 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01319663 0,03570851 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01319663 0,03566655 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01319663 0,03562469 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01319663 0,03558293 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01319663 0,03554126 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01319663 0,03549969 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01319663 0,03545822 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01319663 0,03541685 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01319663 0,03537557 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01319663 0,03533439 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01319663 0,0352933 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01483433 0,03962714 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01483433 0,03958117 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01483433 0,0395353 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01483433 0,03948954 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01483433 0,03944389 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01483433 0,03939834 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01483433 0,0393529 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01483433 0,03930756 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01483433 0,03926233 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01483433 0,0392172 ! GTP metabolic process GO:0046039 9 9 0,000 0,01483433 0,03917217 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01483433 0,03912725 ! social behavior GO:0035176 14 9 0,000 0,01483433 0,03908243 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01483433 0,03903772 ! artery development GO:0060840 19 9 0,000 0,01483433 0,0389931 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01483433 0,03894859 ! response to pain GO:0048265 16 9 0,000 0,01483433 0,03890418 ! protein complex disassembly GO:0043241 17 9 0,000 0,01483433 0,03885987 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01483433 0,03881566 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01483433 0,03877155 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01483433 0,03872754 ! lung alveolus development GO:0048286 17 9 0,000 0,01483433 0,03868363 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01483433 0,03863982 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01483433 0,03859611 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01483433 0,0385525 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01483433 0,03850899 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01483433 0,03846557 ! protein targeting to ER GO:0045047 19 9 0,000 0,01483433 0,03842226 ! T cell selection GO:0045058 18 9 0,000 0,01483433 0,03837904 ! endoderm development GO:0007492 12 9 0,000 0,01483433 0,03833592 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01483433 0,03829289 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01483433 0,03824996 ! arginine catabolic process GO:0006527 10 9 0,000 0,01483433 0,03820713 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01483433 0,03816439 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01483433 0,03812175 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01483433 0,0380792 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01483433 0,03803675 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01483433 0,03799439 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01483433 0,03795213 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01483433 0,03790996 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01483433 0,03786788 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01483433 0,0378259 ! mannose metabolic process GO:0006013 9 9 0,000 0,01483433 0,03778401 ! receptor clustering GO:0043113 15 9 0,000 0,01483433 0,03774222 ! epithelial cell development GO:0002064 10 9 0,000 0,01483433 0,03770051 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01483433 0,0376589 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01483433 0,03761738 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01483433 0,03757595 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01483433 0,03753461 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01483433 0,03749337 ! motor axon guidance GO:0008045 14 9 0,000 0,01483433 0,03745221 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01483433 0,03741115 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01483433 0,03737017 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01483433 0,03732928 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01483433 0,03728849 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01483433 0,03724778 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01483433 0,03720716 ! DNA ligation GO:0006266 14 9 0,000 0,01483433 0,03716663 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01483433 0,03712619 ! response to amine stimulus GO:0014075 13 9 0,000 0,01483433 0,03708583 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01483433 0,03704556 ! erythrocyte development GO:0048821 11 9 0,000 0,01483433 0,03700538 ! renal water homeostasis GO:0003091 14 9 0,000 0,01483433 0,03696529 ! postreplication repair GO:0006301 11 9 0,000 0,01483433 0,03692529 ! mRNA cleavage GO:0006379 13 9 0,000 0,01483433 0,03688537 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01483433 0,03684553 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01483433 0,03680579 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01483433 0,03676613 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01483433 0,03672655 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01483433 0,03668706 ! acid secretion GO:0046717 14 9 0,000 0,01483433 0,03664765 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01483433 0,03660833 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01483433 0,03656909 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01483433 0,03652994 ! purine base metabolic process GO:0006144 18 9 0,000 0,01483433 0,03649087 ! oocyte differentiation GO:0009994 12 9 0,000 0,01483433 0,03645189 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01483433 0,03641298 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01483433 0,03637416 ! spleen development GO:0048536 15 9 0,000 0,01483433 0,03633543 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01483433 0,03629677 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01483433 0,0362582 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01483433 0,03621971 ! detection of calcium ion GO:0005513 13 9 0,000 0,01483433 0,0361813 ! blastocyst formation GO:0001825 12 9 0,000 0,01483433 0,03614297 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01483433 0,03610472 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01483433 0,03606656 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01483433 0,03602847 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01483433 0,03599047 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01483433 0,03595254 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01483433 0,0359147 ! prepulse inhibition GO:0060134 14 9 0,000 0,01483433 0,03587693 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01483433 0,03583925 ! insulin secretion GO:0030073 17 9 0,000 0,01483433 0,03580164 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01483433 0,03576411 ! response to nicotine GO:0035094 16 9 0,000 0,01483433 0,03572666 ! nucleus localization GO:0051647 15 9 0,000 0,01483433 0,03568929 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01483433 0,035652 ! localization within membrane GO:0051668 15 9 0,000 0,01483433 0,03561479 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01646942 0,03949912 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01646942 0,03945797 ! neuron fate specification GO:0048665 11 10 0,000 0,01646942 0,03941691 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01646942 0,03937594 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01646942 0,03933505 ! thyroid gland development GO:0030878 19 10 0,000 0,01646942 0,03929425 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,01646942 0,03925353 ! synapsis GO:0007129 13 10 0,000 0,01646942 0,03921289 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01646942 0,03917234 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01646942 0,03913188 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01646942 0,03909149 ! sulfate transport GO:0008272 12 10 0,000 0,01646942 0,03905119 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01646942 0,03901097 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01646942 0,03897084 ! androgen metabolic process GO:0008209 13 10 0,000 0,01646942 0,03893079 ! phospholipid efflux GO:0033700 16 10 0,000 0,01646942 0,03889082 ! hippocampus development GO:0021766 19 10 0,000 0,01646942 0,03885093 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01646942 0,03881112 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01646942 0,0387714 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01646942 0,03873175 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01646942 0,03869219 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01646942 0,03865271 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,01646942 0,03861331 ! pathogenesis GO:0009405 13 10 0,000 0,01646942 0,03857399 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01646942 0,03853475 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01646942 0,03849558 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01646942 0,0384565 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01646942 0,0384175 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,01646942 0,03837858 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01646942 0,03833973 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01646942 0,03830097 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01646942 0,03826228 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01646942 0,03822367 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01646942 0,03818514 ! response to X-ray GO:0010165 16 10 0,000 0,01646942 0,03814668 ! B cell proliferation GO:0042100 14 10 0,000 0,01646942 0,0381083 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01646942 0,03807001 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01646942 0,03803178 ! forebrain cell migration GO:0021885 17 10 0,000 0,01646942 0,03799364 ! lipid digestion GO:0044241 15 10 0,000 0,01646942 0,03795557 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01646942 0,03791757 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01646942 0,03787966 ! UV protection GO:0009650 14 10 0,000 0,01646942 0,03784181 ! entry into host cell GO:0030260 20 10 0,000 0,01646942 0,03780405 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01646942 0,03776636 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01646942 0,03772874 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01646942 0,0376912 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01646942 0,03765373 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01646942 0,03761634 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01646942 0,03757902 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01646942 0,03754178 ! regulation of organ growth GO:0046620 11 10 0,000 0,01646942 0,03750461 ! response to dsRNA GO:0043331 18 10 0,000 0,01646942 0,03746751 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01646942 0,03743049 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01646942 0,03739354 ! embryonic axis specification GO:0000578 12 10 0,000 0,01646942 0,03735666 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01646942 0,03731986 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01646942 0,03728313 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01646942 0,03724647 ! cranial nerve development GO:0021545 12 10 0,000 0,01646942 0,03720988 ! fucose catabolic process GO:0019317 16 10 0,000 0,01646942 0,03717336 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01646942 0,03713692 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01646942 0,03710054 ! protein sumoylation GO:0016925 12 10 0,000 0,01646942 0,03706424 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01646942 0,03702801 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01646942 0,03699185 ! zymogen activation GO:0031638 14 10 0,000 0,01646942 0,03695576 ! salivary gland development GO:0007431 22 10 0,000 0,01646942 0,03691974 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01646942 0,03688379 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01646942 0,03684791 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01646942 0,0368121 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01646942 0,03677636 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,01646942 0,03674069 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01646942 0,03670509 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01646942 0,03666956 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01646942 0,0366341 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,01646942 0,0365987 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01646942 0,03656337 ! detection of bacterium GO:0016045 10 10 0,000 0,01646942 0,03652811 ! embryonic gut development GO:0048566 11 10 0,000 0,01646942 0,03649292 ! activation of innate immune response GO:0002218 10 10 0,000 0,01646942 0,0364578 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,01646942 0,03642275 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01646942 0,03638776 ! developmental induction GO:0031128 13 10 0,000 0,01646942 0,03635284 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01646942 0,03631798 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01646942 0,03628319 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01646942 0,03624847 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01646942 0,03621382 ! rRNA transcription GO:0009303 17 11 0,000 0,01810188 0,03976535 ! respiratory burst GO:0045730 14 11 0,000 0,01810188 0,0397274 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01810188 0,03968953 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01810188 0,03965173 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01810188 0,039614 ! virus-host interaction GO:0019048 17 11 0,000 0,01810188 0,03957635 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,01810188 0,03953876 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,01810188 0,03950125 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01810188 0,03946381 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,01810188 0,03942644 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,01810188 0,03938914 ! mating GO:0007618 14 11 0,000 0,01810188 0,03935191 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01810188 0,03931475 ! T cell proliferation GO:0042098 20 11 0,000 0,01810188 0,03927766 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01810188 0,03924064 ! bone resorption GO:0045453 16 11 0,000 0,01810188 0,03920369 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01810188 0,03916681 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01810188 0,03913 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01810188 0,03909326 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01810188 0,03905658 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01810188 0,03901998 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01810188 0,03898344 ! syncytium formation GO:0006949 15 11 0,000 0,01810188 0,03894698 ! plasma membrane organization GO:0007009 18 11 0,000 0,01810188 0,03891058 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01810188 0,03887425 ! focal adhesion formation GO:0048041 24 11 0,000 0,01810188 0,03883798 ! mitotic spindle organization GO:0007052 15 11 0,000 0,01810188 0,03880179 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,01810188 0,03876566 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01810188 0,0387296 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01810188 0,03869361 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01810188 0,03865768 ! adult heart development GO:0007512 11 11 0,000 0,01810188 0,03862182 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01810188 0,03858602 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01810188 0,0385503 ! temperature homeostasis GO:0001659 16 11 0,000 0,01810188 0,03851463 ! L-glutamate transport GO:0015813 16 11 0,000 0,01810188 0,03847904 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01810188 0,03844351 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01810188 0,03840804 ! stem cell development GO:0048864 29 11 0,000 0,01810188 0,03837264 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01810188 0,03833731 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01810188 0,03830204 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,01810188 0,03826684 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01810188 0,0382317 ! vasoconstriction GO:0042310 15 11 0,000 0,01810188 0,03819662 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01810188 0,03816161 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01810188 0,03812667 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01810188 0,03809178 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,01810188 0,03805696 ! ribosome assembly GO:0042255 13 11 0,000 0,01810188 0,03802221 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01810188 0,03798752 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,01810188 0,03795289 ! chromatin silencing GO:0006342 19 11 0,000 0,01810188 0,03791832 ! nucleosome positioning GO:0016584 13 11 0,000 0,01810188 0,03788382 ! T cell homeostasis GO:0043029 20 11 0,000 0,01810188 0,03784938 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01810188 0,037815 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,01810188 0,03778069 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01810188 0,03774644 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01810188 0,03771225 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01810188 0,03767812 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01810188 0,03764405 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01810188 0,03761004 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01810188 0,0375761 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,01810188 0,03754222 ! male genitalia development GO:0030539 13 11 0,000 0,01810188 0,0375084 ! cholesterol efflux GO:0033344 19 11 0,000 0,01810188 0,03747463 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,01810188 0,03744093 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,01810188 0,03740729 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01810188 0,03737372 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01810188 0,0373402 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01810188 0,03730674 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01810188 0,03727334 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01810188 0,03724 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01810188 0,03720672 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01810188 0,0371735 ! lysogeny GO:0030069 18 11 0,000 0,01810188 0,03714034 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,01810188 0,03710724 ! acrosome reaction GO:0007340 13 11 0,000 0,01810188 0,03707419 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01810188 0,03704121 ! lactation GO:0007595 20 12 0,000 0,01973172 0,04034041 ! reproductive cellular process GO:0048610 14 12 0,000 0,01973172 0,04030459 ! tRNA modification GO:0006400 14 12 0,000 0,01973172 0,04026883 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,01973172 0,04023313 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,01973172 0,04019749 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,01973172 0,04016192 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,01973172 0,04012641 ! non-recombinational repair GO:0000726 19 12 0,000 0,01973172 0,04009096 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,01973172 0,04005557 ! peroxisomal transport GO:0043574 21 12 0,000 0,01973172 0,04002025 ! cartilage condensation GO:0001502 18 12 0,000 0,01973172 0,03998499 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,01973172 0,03994979 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,01973172 0,03991466 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01973172 0,03987958 ! palate development GO:0060021 15 12 0,000 0,01973172 0,03984457 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,01973172 0,03980962 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,01973172 0,03977473 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,01973172 0,0397399 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01973172 0,03970513 ! arginine metabolic process GO:0006525 13 12 0,000 0,01973172 0,03967042 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,01973172 0,03963578 ! methionine metabolic process GO:0006555 13 12 0,000 0,01973172 0,03960119 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,01973172 0,03956667 ! Golgi organization GO:0007030 18 12 0,000 0,01973172 0,0395322 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,01973172 0,03949779 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,01973172 0,03946345 ! monoamine transport GO:0015844 13 12 0,000 0,01973172 0,03942916 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01973172 0,03939494 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,01973172 0,03936077 ! L-amino acid transport GO:0015807 20 12 0,000 0,01973172 0,03932666 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,01973172 0,03929261 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01973172 0,03925862 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,01973172 0,03922469 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01973172 0,03919082 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,01973172 0,039157 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,01973172 0,03912325 ! cerebellum development GO:0021549 13 12 0,000 0,01973172 0,03908955 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01973172 0,03905591 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01973172 0,03902233 ! histone methylation GO:0016571 15 12 0,000 0,01973172 0,0389888 ! autonomic nervous system development GO:0048483 23 12 0,000 0,01973172 0,03895534 ! gland morphogenesis GO:0022612 23 12 0,000 0,01973172 0,03892193 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,01973172 0,03888857 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,01973172 0,03885528 ! response to gamma radiation GO:0010332 20 12 0,000 0,01973172 0,03882204 ! regulation of epidermis development GO:0045682 17 12 0,000 0,01973172 0,03878886 ! intestinal absorption GO:0050892 19 12 0,000 0,01973172 0,03875574 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,01973172 0,03872267 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01973172 0,03868966 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,01973172 0,0386567 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,01973172 0,0386238 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,01973172 0,03859096 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01973172 0,03855817 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,01973172 0,03852544 ! microspike assembly GO:0030035 23 12 0,000 0,01973172 0,03849276 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,01973172 0,03846014 ! response to cold GO:0009409 14 12 0,000 0,01973172 0,03842757 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,02135896 0,04156142 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02135896 0,04152629 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02135896 0,04149122 GO:0006182|cGMP biosynthetic process, ! water transport GO:0006833 17 13 0,000 0,02135896 0,04145621 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02135896 0,04142125 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02135896 0,04138636 ! lipid localization GO:0010876 24 13 0,000 0,02135896 0,04135152 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02135896 0,04131674 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02135896 0,04128202 ! organelle fusion GO:0048284 28 13 0,000 0,02135896 0,04124736 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02135896 0,04121276 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02135896 0,04117821 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,02135896 0,04114372 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02135896 0,04110929 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02135896 0,04107492 ! response to hexose stimulus GO:0009746 19 13 0,000 0,02135896 0,04104061 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glutamate metabolic process GO:0006536 18 13 0,000 0,02135896 0,04100635 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02135896 0,04097215 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02135896 0,040938 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02135896 0,04090392 ! NAD metabolic process GO:0019674 21 13 0,000 0,02135896 0,04086989 ! exocrine system development GO:0035272 27 13 0,000 0,02135896 0,04083591 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02135896 0,040802 ! bone mineralization GO:0030282 15 13 0,000 0,02135896 0,04076814 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02135896 0,04073433 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02135896 0,04070058 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02135896 0,04066689 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02135896 0,04063325 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,02135896 0,04059967 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02135896 0,04056615 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,02135896 0,04053268 ! genitalia development GO:0048806 15 13 0,000 0,02135896 0,04049926 ! regulation of cellular pH GO:0030641 20 13 0,000 0,02135896 0,0404659 ! cellular pigmentation GO:0033059 24 13 0,000 0,02135896 0,0404326 ! tissue regeneration GO:0042246 21 13 0,000 0,02135896 0,04039935 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02135896 0,04036615 ! cofactor transport GO:0051181 19 13 0,000 0,02135896 0,04033301 ! NADP metabolic process GO:0006739 18 13 0,000 0,02135896 0,04029992 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02135896 0,04026689 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02135896 0,04023391 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02135896 0,04020099 ! gas transport GO:0015669 18 13 0,000 0,02135896 0,04016811 ! regulation of RNA stability GO:0043487 28 13 0,000 0,02135896 0,0401353 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02135896 0,04010253 ! regulation of axon extension GO:0030516 23 13 0,000 0,02135896 0,04006982 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,02135896 0,04003717 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02135896 0,04000456 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02135896 0,03997201 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02135896 0,03993952 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02135896 0,03990707 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02135896 0,03987468 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,02298358 0,04287287 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,02298358 0,04283812 ! superoxide anion generation GO:0042554 18 14 0,000 0,02298358 0,04280344 ! neuron maturation GO:0042551 21 14 0,000 0,02298358 0,04276881 ! regulation of S phase GO:0033261 18 14 0,000 0,02298358 0,04273423 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,02298358 0,04269971 ! myotube differentiation GO:0014902 21 14 0,000 0,02298358 0,04266525 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,02298358 0,04263084 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,02298358 0,04259649 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,02298358 0,04256219 ! inositol metabolic process GO:0006020 20 14 0,000 0,02298358 0,04252795 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,02298358 0,04249377 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,02298358 0,04245963 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,02298358 0,04242556 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,02298358 0,04239153 ! gene silencing by RNA GO:0031047 20 14 0,000 0,02298358 0,04235757 ! response to cAMP GO:0051591 19 14 0,000 0,02298358 0,04232365 ! limbic system development GO:0021761 25 14 0,000 0,02298358 0,0422898 ! startle response GO:0001964 21 14 0,000 0,02298358 0,04225599 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,02298358 0,04222224 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,02298358 0,04218854 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,02298358 0,0421549 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,02298358 0,04212131 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,02298358 0,04208777 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,02298358 0,04205429 ! glycine metabolic process GO:0006544 22 14 0,000 0,02298358 0,04202086 ! pituitary gland development GO:0021983 23 14 0,000 0,02298358 0,04198749 ! cellular response to starvation GO:0009267 21 14 0,000 0,02298358 0,04195416 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,02298358 0,04192089 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,02298358 0,04188767 ! regulation of heart rate GO:0002027 23 14 0,000 0,02298358 0,04185451 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,02298358 0,0418214 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,02298358 0,04178834 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,02298358 0,04175533 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,02298358 0,04172237 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,02298358 0,04168947 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,02298358 0,04165661 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,02298358 0,04162381 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,02298358 0,04159107 ! axon cargo transport GO:0008088 27 14 0,000 0,02298358 0,04155837 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,02298358 0,04152572 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,02298358 0,04149313 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,02298358 0,04146058 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,02298358 0,04142809 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02298358 0,04139565 ! mRNA splice site selection GO:0006376 26 14 0,000 0,02298358 0,04136326 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,02298358 0,04133092 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,02298358 0,04129863 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,02298358 0,04126639 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,02298358 0,0412342 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,02298358 0,04120206 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,02298358 0,04116997 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,02298358 0,04113793 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,02298358 0,04110594 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,02298358 0,041074 ! cell killing GO:0001906 20 14 0,000 0,02298358 0,04104211 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,02298358 0,04101027 ! cilium assembly GO:0042384 20 14 0,000 0,02298358 0,04097848 ! peptide hormone secretion GO:0030072 23 14 0,000 0,02298358 0,04094674 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,02460561 0,04380255 ! positive regulation of cell size GO:0045793 20 15 0,000 0,02460561 0,04376867 ! metencephalon development GO:0022037 19 15 0,000 0,02460561 0,04373485 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02460561 0,04370108 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,02460561 0,04366736 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,02460561 0,04363369 ! skin development GO:0043588 25 15 0,000 0,02460561 0,04360007 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,02460561 0,04356651 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,02460561 0,043533 ! lipid phosphorylation GO:0046834 23 15 0,000 0,02460561 0,04349953 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,02460561 0,04346612 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,02460561 0,04343277 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,02460561 0,04339946 ! bile acid metabolic process GO:0008206 22 15 0,000 0,02460561 0,0433662 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,02460561 0,043333 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,02460561 0,04329984 ! adult walking behavior GO:0007628 25 15 0,000 0,02460561 0,04326674 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02460561 0,04323369 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,02460561 0,04320068 ! myoblast differentiation GO:0045445 27 15 0,000 0,02460561 0,04316773 ! centrosome cycle GO:0007098 16 15 0,000 0,02460561 0,04313483 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,02460561 0,04310198 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,02460561 0,04306917 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,02460561 0,04303642 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,02460561 0,04300372 ! cerebral cortex development GO:0021987 29 15 0,000 0,02460561 0,04297107 ! response to osmotic stress GO:0006970 22 15 0,000 0,02460561 0,04293846 ! vesicle coating GO:0006901 25 15 0,000 0,02460561 0,04290591 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,02460561 0,0428734 ! DNA integration GO:0015074 22 15 0,000 0,02460561 0,04284095 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,02460561 0,04280854 ! peptide secretion GO:0002790 27 15 0,000 0,02460561 0,04277619 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,02460561 0,04274388 ! regulation of vasodilation GO:0042312 24 15 0,000 0,02460561 0,04271162 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,02460561 0,04267941 ! neuron recognition GO:0008038 22 15 0,000 0,02460561 0,04264724 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,02460561 0,04261513 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,02460561 0,04258307 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,02460561 0,04255105 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,02460561 0,04251908 ! biomineral formation GO:0031214 18 15 0,000 0,02460561 0,04248716 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,02460561 0,04245528 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,02460561 0,04242346 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,02460561 0,04239168 ! dopamine metabolic process GO:0042417 30 15 0,000 0,02460561 0,04235995 ! organic cation transport GO:0015695 19 15 0,000 0,02460561 0,04232827 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,02460561 0,04229663 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,02460561 0,04226504 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,02460561 0,0422335 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,02460561 0,04220201 ! defense response to virus GO:0051607 27 15 0,000 0,02460561 0,04217056 ! peptide hormone processing GO:0016486 19 15 0,000 0,02460561 0,04213916 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,02460561 0,04210781 ! protein secretion GO:0009306 27 16 0,000 0,02622503 0,04484577 ! hormone secretion GO:0046879 25 16 0,000 0,02622503 0,04481245 ! bone remodeling GO:0046849 24 16 0,000 0,02622503 0,04477919 ! endothelial cell migration GO:0043542 22 16 0,000 0,02622503 0,04474597 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,02622503 0,0447128 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02622503 0,04467968 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,02622503 0,04464661 ! glial cell development GO:0021782 24 16 0,000 0,02622503 0,04461358 ! patterning of blood vessels GO:0001569 24 16 0,000 0,02622503 0,04458061 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,02622503 0,04454768 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,02622503 0,04451481 ! protein polyubiquitination GO:0000209 26 16 0,000 0,02622503 0,04448198 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,02622503 0,0444492 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,02622503 0,04441647 ! fructose metabolic process GO:0006000 20 16 0,000 0,02622503 0,04438378 ! regulation of protein binding GO:0043393 27 16 0,000 0,02622503 0,04435115 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,02622503 0,04431856 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,02622503 0,04428602 ! protein export from nucleus GO:0006611 24 16 0,000 0,02622503 0,04425353 ! negative regulation of immune response GO:0050777 28 16 0,000 0,02622503 0,04422109 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,02622503 0,04418869 ! DNA replication initiation GO:0006270 25 16 0,000 0,02622503 0,04415634 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,02622503 0,04412404 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,02622503 0,04409179 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,02622503 0,04405958 ! diencephalon development GO:0021536 25 16 0,000 0,02622503 0,04402742 ! oogenesis GO:0048477 23 16 0,000 0,02622503 0,04399531 ! G1 phase GO:0051318 27 16 0,000 0,02622503 0,04396324 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,02622503 0,04393122 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02622503 0,04389925 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,02622503 0,04386732 ! steroid catabolic process GO:0006706 22 16 0,000 0,02622503 0,04383544 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02622503 0,0438036 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,02622503 0,04377182 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,02622503 0,04374008 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,02622503 0,04370838 ! sperm-egg recognition GO:0035036 16 16 0,000 0,02622503 0,04367673 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,02622503 0,04364513 ! nerve development GO:0021675 18 16 0,000 0,02622503 0,04361357 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,02622503 0,04358205 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,02622503 0,04355059 ! negative regulation of translation GO:0017148 22 16 0,000 0,02622503 0,04351917 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,02784185 0,0461689 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,02784185 0,04613564 ! negative regulation of defense response GO:0031348 19 17 0,000 0,02784185 0,04610242 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,02784185 0,04606925 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,02784185 0,04603613 ! glycerol metabolic process GO:0006071 20 17 0,000 0,02784185 0,04600306 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,02784185 0,04597004 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,02784185 0,04593706 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02784185 0,04590413 ! signal complex assembly GO:0007172 29 17 0,000 0,02784185 0,04587125 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,02784185 0,04583841 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,02784185 0,04580562 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,02784185 0,04577288 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,02784185 0,04574019 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,02784185 0,04570754 ! memory GO:0007613 25 17 0,000 0,02784185 0,04567494 ! keratinization GO:0031424 17 17 0,000 0,02784185 0,04564238 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,02784185 0,04560987 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,02784185 0,04557741 ! retinoid metabolic process GO:0001523 22 17 0,000 0,02784185 0,04554499 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,02784185 0,04551262 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,02784185 0,0454803 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,02784185 0,04544802 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,02784185 0,04541579 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,02784185 0,0453836 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,02784185 0,04535146 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,02784185 0,04531936 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,02784185 0,04528731 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,02784185 0,04525531 ! heme metabolic process GO:0042168 27 17 0,000 0,02784185 0,04522335 ! actin filament bundle formation GO:0051017 26 17 0,000 0,02784185 0,04519143 ! neuromuscular junction development GO:0007528 23 17 0,000 0,02784185 0,04515956 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,02784185 0,04512774 ! body fluid secretion GO:0007589 27 17 0,000 0,02784185 0,04509596 ! stem cell differentiation GO:0048863 36 17 0,000 0,02784185 0,04506422 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02784185 0,04503253 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,02784185 0,04500089 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,02784185 0,04496929 ! sensory perception of pain GO:0019233 23 17 0,000 0,02784185 0,04493773 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,02784185 0,04490621 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,02784185 0,04487475 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,02784185 0,04484332 ! synaptogenesis GO:0007416 24 17 0,000 0,02784185 0,04481194 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,02784185 0,0447806 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02784185 0,04474931 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,02784185 0,04471806 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,02784185 0,04468685 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,02784185 0,04465569 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,02784185 0,04462457 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,02784185 0,0445935 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,02784185 0,04456247 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,02784185 0,04453148 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,02945609 0,04708061 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,02945609 0,04704792 ! positive regulation of translation GO:0045727 28 18 0,000 0,02945609 0,04701527 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,02945609 0,04698266 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02945609 0,0469501 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,02945609 0,04691759 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02945609 0,04688512 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,02945609 0,0468527 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,02945609 0,04682032 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,02945609 0,04678798 ! axis specification GO:0009798 26 18 0,000 0,02945609 0,04675569 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,02945609 0,04672345 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,02945609 0,04669125 ! pancreas development GO:0031016 26 18 0,000 0,02945609 0,04665909 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,02945609 0,04662698 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,02945609 0,04659491 ! glutamine metabolic process GO:0006541 23 18 0,000 0,02945609 0,04656289 ! response to retinoic acid GO:0032526 25 18 0,000 0,02945609 0,04653091 ! pigmentation during development GO:0048066 31 18 0,000 0,02945609 0,04649897 ! central nervous system neuron development GO:0021954 30 18 0,000 0,02945609 0,04646708 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,02945609 0,04643523 ! fucose metabolic process GO:0006004 26 18 0,000 0,02945609 0,04640342 ! response to fungus GO:0009620 19 18 0,000 0,02945609 0,04637166 ! peptide cross-linking GO:0018149 31 18 0,000 0,02945609 0,04633994 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,02945609 0,04630827 ! heart process GO:0003015 27 18 0,000 0,02945609 0,04627664 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,02945609 0,04624505 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,02945609 0,04621351 ! somitogenesis GO:0001756 24 18 0,000 0,02945609 0,046182 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,02945609 0,04615054 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,02945609 0,04611913 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,02945609 0,04608775 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,02945609 0,04605642 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,02945609 0,04602514 ! vitamin transport GO:0051180 24 18 0,000 0,02945609 0,04599389 ! hormone transport GO:0009914 27 18 0,000 0,02945609 0,04596269 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,02945609 0,04593152 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,02945609 0,04590041 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02945609 0,04586933 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,02945609 0,04583829 ! cell-cell recognition GO:0009988 20 18 0,000 0,02945609 0,0458073 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,02945609 0,04577635 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,02945609 0,04574544 ! regulation of glucose import GO:0046324 21 18 0,000 0,02945609 0,04571457 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,02945609 0,04568375 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,02945609 0,04565296 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,02945609 0,04562222 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,02945609 0,04559152 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,03106773 0,04805365 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,03106773 0,04802136 ! positive regulation of ossification GO:0045778 30 19 0,000 0,03106773 0,04798911 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,03106773 0,0479569 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,03106773 0,04792474 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,03106773 0,04789262 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,03106773 0,04786054 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,03106773 0,0478285 ! regeneration GO:0031099 32 19 0,000 0,03106773 0,04779651 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,03106773 0,04776456 ! response to alkaloid GO:0043279 32 19 0,000 0,03106773 0,04773265 ! sensory perception of taste GO:0050909 23 19 0,000 0,03106773 0,04770079 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,03106773 0,04766897 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,03106773 0,04763719 ! smooth muscle contraction GO:0006939 36 19 0,000 0,03106773 0,04760545 ! peroxisome organization GO:0007031 29 19 0,000 0,03106773 0,04757376 ! digestive system process GO:0022600 30 19 0,000 0,03106773 0,0475421 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,03106773 0,04751049 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,03106773 0,04747893 ! response to vitamin A GO:0033189 26 19 0,000 0,03106773 0,0474474 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,03106773 0,04741591 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,03106773 0,04738447 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,03106773 0,04735307 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,03106773 0,04732171 ! response to starvation GO:0042594 30 19 0,000 0,03106773 0,04729039 ! sex determination GO:0007530 29 19 0,000 0,03106773 0,04725912 ! plasma membrane fusion GO:0045026 23 19 0,000 0,03106773 0,04722788 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,03106773 0,04719669 ! cytolysis GO:0019835 20 19 0,000 0,03106773 0,04716553 ! renal system process GO:0003014 35 19 0,000 0,03106773 0,04713442 ! vasodilation GO:0042311 33 19 0,000 0,03106773 0,04710335 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,03106773 0,04707232 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,03106773 0,04704133 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,03106773 0,04701038 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,03106773 0,04697948 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,03106773 0,04694861 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,03106773 0,04691778 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,03106773 0,046887 ! sarcomere organization GO:0045214 23 19 0,000 0,03106773 0,04685625 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,03106773 0,04682555 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,03106773 0,04679488 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,03106773 0,04676426 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,03106773 0,04673367 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,03106773 0,04670313 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,03106773 0,04667262 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,03106773 0,04664216 ! protein stabilization GO:0050821 26 19 0,000 0,03106773 0,04661173 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,03267679 0,04899389 ! iron ion transport GO:0006826 37 20 0,000 0,03267679 0,04896197 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,03267679 0,04893009 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,03267679 0,04889826 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,03267679 0,04886647 ! response to vitamin GO:0033273 29 20 0,000 0,03267679 0,04883471 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,03267679 0,048803 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,03267679 0,04877133 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,03267679 0,0487397 ! spinal cord development GO:0021510 31 20 0,000 0,03267679 0,04870812 ! response to ethanol GO:0045471 37 20 0,000 0,03267679 0,04867657 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,03267679 0,04864506 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,03267679 0,0486136 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,03267679 0,04858217 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,03267679 0,04855079 ! chromosome condensation GO:0030261 31 20 0,000 0,03267679 0,04851945 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,03267679 0,04848814 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,03267679 0,04845688 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,03267679 0,04842566 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,03267679 0,04839448 ! pallium development GO:0021543 38 20 0,000 0,03267679 0,04836334 ! DNA modification GO:0006304 28 20 0,000 0,03267679 0,04833223 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,03267679 0,04830117 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,03267679 0,04827015 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,03267679 0,04823917 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,03267679 0,04820823 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,03267679 0,04817732 ! collagen catabolic process GO:0030574 25 20 0,000 0,03267679 0,04814646 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,03267679 0,04811564 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,03267679 0,04808485 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,03267679 0,04805411 ! alditol metabolic process GO:0019400 24 20 0,000 0,03267679 0,0480234 ! actin filament-based movement GO:0030048 34 20 0,000 0,03267679 0,04799274 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,03428327 0,05032006 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,03428327 0,05028797 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,03428327 0,05025591 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,03428327 0,0502239 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,03428327 0,05019194 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,03428327 0,05016001 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,03428327 0,05012812 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,03428327 0,05009627 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,03428327 0,05006446 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,03428327 0,0500327 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,03428327 0,05000097 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,03428327 0,04996928 ! vesicle docking GO:0048278 27 21 0,000 0,03428327 0,04993764 ! phototransduction GO:0007602 25 21 0,000 0,03428327 0,04990603 ! dendrite development GO:0016358 35 21 0,000 0,03428327 0,04987447 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,03428327 0,04984294 ! ovarian follicle development GO:0001541 30 21 0,000 0,03428327 0,04981145 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,03428327 0,04978001 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,03428327 0,0497486 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,03428327 0,04971723 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,03428327 0,0496859 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,03428327 0,04965462 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,03428327 0,04962337 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,03428327 0,04959216 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,03428327 0,04956099 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,03428327 0,04952986 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,03428327 0,04949876 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,03428327 0,04946771 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,03428327 0,0494367 ! fatty acid transport GO:0015908 30 21 0,000 0,03428327 0,04940572 ! immunoglobulin production GO:0002377 33 21 0,000 0,03428327 0,04937478 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,03428327 0,04934389 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,03428327 0,04931303 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,03428327 0,04928221 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,03428327 0,04925142 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,03428327 0,04922068 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,03428327 0,04918998 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,03428327 0,04915931 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,03428327 0,04912868 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,03428327 0,04909809 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,03428327 0,04906754 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,03428327 0,04903702 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,03428327 0,04900654 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,03428327 0,04897611 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,03588718 0,05123558 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,03588718 0,05120379 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,03588718 0,05117205 ! viral genome replication GO:0019079 29 22 0,000 0,03588718 0,05114034 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,03588718 0,05110868 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,03588718 0,05107705 ! leukocyte adhesion GO:0007159 38 22 0,000 0,03588718 0,05104546 ! molting cycle process GO:0022404 40 22 0,000 0,03588718 0,05101391 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,03588718 0,0509824 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,03588718 0,05095093 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,03588718 0,0509195 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,03588718 0,05088811 ! vasculogenesis GO:0001570 33 22 0,000 0,03588718 0,05085675 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,03588718 0,05082544 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,03588718 0,05079416 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,03588718 0,05076292 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,03588718 0,05073172 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,03588718 0,05070056 ! lysosome organization GO:0007040 37 22 0,000 0,03588718 0,05066944 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,03588718 0,05063835 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,03588718 0,0506073 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,03588718 0,05057629 ! regulation of behavior GO:0050795 38 22 0,000 0,03588718 0,05054532 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,03588718 0,05051439 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,03588718 0,05048349 ! membrane depolarization GO:0051899 35 22 0,000 0,03588718 0,05045264 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,03588718 0,05042182 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,03588718 0,05039103 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,03588718 0,05036029 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,03588718 0,05032958 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,03588718 0,05029891 ! blastocyst development GO:0001824 37 22 0,000 0,03588718 0,05026828 ! neural tube closure GO:0001843 33 22 0,000 0,03588718 0,05023768 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,03588718 0,05020712 ! protein tetramerization GO:0051262 39 22 0,000 0,03588718 0,0501766 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,03748851 0,0523837 ! neuron fate commitment GO:0048663 32 23 0,000 0,03748851 0,0523519 ! embryonic pattern specification GO:0009880 31 23 0,000 0,03748851 0,05232013 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,03748851 0,0522884 ! myelination GO:0042552 35 23 0,000 0,03748851 0,05225671 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,03748851 0,05222506 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,03748851 0,05219345 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,03748851 0,05216187 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,03748851 0,05213034 ! vesicle targeting GO:0006903 32 23 0,000 0,03748851 0,05209884 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,03748851 0,05206738 ! osteoblast differentiation GO:0001649 40 23 0,000 0,03748851 0,05203596 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,03748851 0,05200457 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,03748851 0,05197322 ! interaction with host GO:0051701 37 23 0,000 0,03748851 0,05194191 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,03748851 0,05191064 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,03748851 0,05187941 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,03748851 0,05184821 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,03748851 0,05181705 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,03748851 0,05178593 ! cell fate determination GO:0001709 45 23 0,000 0,03748851 0,05175485 ! pentose metabolic process GO:0019321 31 23 0,000 0,03748851 0,0517238 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,03748851 0,05169279 ! spermatid development GO:0007286 33 23 0,000 0,03748851 0,05166182 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,03748851 0,05163088 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,03748851 0,05159999 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,03748851 0,05156913 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,03748851 0,0515383 ! telomere organization GO:0032200 32 23 0,000 0,03748851 0,05150751 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,03748851 0,05147676 ! regulation of amine transport GO:0051952 38 23 0,000 0,03748851 0,05144605 ! liver development GO:0001889 40 23 0,000 0,03748851 0,05141537 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,03908728 0,05357612 ! initiation of viral infection GO:0019059 42 24 0,000 0,03908728 0,05354421 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,03908728 0,05351234 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,03908728 0,05348051 ! superoxide metabolic process GO:0006801 32 24 0,000 0,03908728 0,05344871 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,03908728 0,05341696 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,03908728 0,05338524 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,03908728 0,05335355 ! sperm motility GO:0030317 27 24 0,000 0,03908728 0,05332191 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,03908728 0,0532903 ! vacuole organization GO:0007033 39 24 0,000 0,03908728 0,05325873 ! receptor metabolic process GO:0043112 37 24 0,000 0,03908728 0,0532272 ! response to toxin GO:0009636 38 24 0,000 0,03908728 0,0531957 ! primary neural tube formation GO:0014020 35 24 0,000 0,03908728 0,05316424 ! negative regulation of cell development GO:0010721 56 24 0,000 0,03908728 0,05313282 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,03908728 0,05310144 ! base-excision repair GO:0006284 31 24 0,000 0,03908728 0,05307009 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,03908728 0,05303878 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,03908728 0,05300751 ! glutathione metabolic process GO:0006749 29 24 0,000 0,03908728 0,05297627 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,03908728 0,05294507 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,03908728 0,05291391 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,03908728 0,05288279 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,04068348 0,05500999 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,04068348 0,05497767 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,04068348 0,05494539 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,04068348 0,05491314 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,04068348 0,05488094 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,04068348 0,05484877 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,04068348 0,05481664 ! peptide transport GO:0015833 43 25 0,000 0,04068348 0,05478454 ! male gonad development GO:0008584 33 25 0,000 0,04068348 0,05475249 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,04068348 0,05472047 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,04068348 0,05468848 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,04068348 0,05465654 ! phospholipid transport GO:0015914 35 25 0,000 0,04068348 0,05462463 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,04068348 0,05459276 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,04068348 0,05456093 ! detection of light stimulus GO:0009583 30 25 0,000 0,04068348 0,05452914 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,04068348 0,05449738 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,04068348 0,05446566 ! leukocyte proliferation GO:0070661 39 25 0,000 0,04068348 0,05443397 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,04068348 0,05440232 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,04227712 0,05650051 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,04227712 0,05646769 ! translational initiation GO:0006413 43 26 0,000 0,04227712 0,05643492 ! regulation of pH GO:0006885 36 26 0,000 0,04227712 0,05640219 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,04227712 0,05636949 ! circadian rhythm GO:0007623 42 26 0,000 0,04227712 0,05633683 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,04227712 0,05630421 ! post-embryonic development GO:0009791 42 26 0,000 0,04227712 0,05627163 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,04227712 0,05623908 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,04227712 0,05620657 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,04227712 0,0561741 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,04227712 0,05614167 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,04227712 0,05610927 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,04227712 0,05607691 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,04227712 0,05604459 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,04227712 0,05601231 ! regulation of coagulation GO:0050818 39 26 0,000 0,04227712 0,05598006 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,0438682 0,05805343 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,0438682 0,05802005 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,0438682 0,0579867 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,0438682 0,0579534 ! membrane docking GO:0022406 39 27 0,000 0,0438682 0,05792013 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,0438682 0,0578869 ! catechol metabolic process GO:0009712 43 27 0,000 0,0438682 0,05785371 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,0438682 0,05782055 ! acute-phase response GO:0006953 42 27 0,000 0,0438682 0,05778744 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,0438682 0,05775436 ! myofibril assembly GO:0030239 36 27 0,000 0,0438682 0,05772132 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,0438682 0,05768832 ! response to ionizing radiation GO:0010212 47 27 0,000 0,0438682 0,05765535 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,0438682 0,05762242 ! natural killer cell activation GO:0030101 35 27 0,000 0,0438682 0,05758953 ! lipid oxidation GO:0034440 38 27 0,000 0,0438682 0,05755668 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,0438682 0,05752387 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,0438682 0,05749109 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,0438682 0,05745835 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,0438682 0,05742565 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein transport GO:0051224 49 27 0,000 0,0438682 0,05739298 ! gene silencing GO:0016458 41 27 0,000 0,0438682 0,05736035 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,04545673 0,05940369 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,04545673 0,05936995 ! phenol metabolic process GO:0018958 44 28 0,000 0,04545673 0,05933626 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,04545673 0,0593026 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,04545673 0,05926898 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,04545673 0,0592354 ! cell junction assembly GO:0034329 56 28 0,000 0,04545673 0,05920186 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,04545673 0,05916836 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,04545673 0,05913489 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,04545673 0,05910146 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,04545673 0,05906807 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,04545673 0,05903472 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,04545673 0,0590014 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,04545673 0,05896813 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,04545673 0,05893489 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,04545673 0,05890168 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,04545673 0,05886852 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,04545673 0,05883539 ! mesoderm formation GO:0001707 46 28 0,000 0,04545673 0,0588023 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,04545673 0,05876925 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,04545673 0,05873623 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,04545673 0,05870325 ! ensheathment of neurons GO:0007272 43 28 0,000 0,04545673 0,05867031 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,04545673 0,0586374 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,04545673 0,05860453 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,04545673 0,0585717 ! neural tube formation GO:0001841 41 28 0,000 0,04545673 0,05853891 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,04704272 0,06054743 ! regulation of innate immune response GO:0045088 38 29 0,000 0,04704272 0,06051356 ! ovulation cycle process GO:0022602 41 29 0,000 0,04704272 0,06047974 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,04704272 0,06044595 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,04704272 0,0604122 ! mismatch repair GO:0006298 34 29 0,000 0,04704272 0,06037849 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,04704272 0,06034481 ! muscle cell development GO:0055001 38 29 0,000 0,04704272 0,06031118 ! formation of primary germ layer GO:0001704 48 29 0,000 0,04704272 0,06027758 ! telencephalon development GO:0021537 52 29 0,000 0,04704272 0,06024401 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,04704272 0,06021049 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,04704272 0,060177 ! tissue homeostasis GO:0001894 42 29 0,000 0,04704272 0,06014355 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,04862616 0,06213342 ! organic anion transport GO:0015711 51 30 0,000 0,04862616 0,06209892 ! cholesterol transport GO:0030301 46 30 0,000 0,04862616 0,06206446 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,04862616 0,06203004 ! spliceosome assembly GO:0000245 49 30 0,000 0,04862616 0,06199565 ! spindle organization GO:0007051 37 30 0,000 0,04862616 0,06196131 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,04862616 0,061927 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,04862616 0,06189273 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,04862616 0,06185849 ! ceramide metabolic process GO:0006672 43 30 0,000 0,04862616 0,0618243 ! ovulation cycle GO:0042698 43 30 0,000 0,04862616 0,06179014 ! hindbrain development GO:0030902 45 30 0,000 0,04862616 0,06175602 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,04862616 0,06172194 ! adult locomotory behavior GO:0008344 47 30 0,000 0,04862616 0,0616879 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,04862616 0,06165389 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,04862616 0,06161992 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,04862616 0,06158599 ! response to heat GO:0009408 41 30 0,000 0,04862616 0,0615521 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,04862616 0,06151824 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,04862616 0,06148442 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,05020705 0,06344848 ! negative regulation of secretion GO:0051048 49 31 0,000 0,05020705 0,06341363 ! mammary gland development GO:0030879 57 31 0,000 0,05020705 0,06337883 ! glial cell differentiation GO:0010001 55 31 0,000 0,05020705 0,06334406 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,05020705 0,06330933 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,05020705 0,06327464 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,05020705 0,06323999 ! odontogenesis GO:0042476 50 31 0,000 0,05020705 0,06320538 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,05020705 0,0631708 ! segmentation GO:0035282 41 31 0,000 0,05020705 0,06313626 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,05020705 0,06310176 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,05020705 0,0630673 ! metanephros development GO:0001656 58 31 0,000 0,05020705 0,06303287 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,05020705 0,06299849 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,05020705 0,06296414 ! cell fate specification GO:0001708 37 31 0,000 0,05020705 0,06292982 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,05020705 0,06289555 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,05020705 0,06286131 ! RNA modification GO:0009451 40 31 0,000 0,05020705 0,06282711 ! regulation of muscle development GO:0048634 48 32 0,000 0,05178542 0,06476697 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,05178542 0,06473177 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,05178542 0,06469661 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,05178542 0,06466149 ! meiosis I GO:0007127 52 32 0,000 0,05178542 0,0646264 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,05178542 0,06459135 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,05178542 0,06455635 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,05178542 0,06452137 ! peripheral nervous system development GO:0007422 53 32 0,000 0,05178542 0,06448644 ! regulation of protein stability GO:0031647 48 32 0,000 0,05178542 0,06445155 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,05178542 0,06441669 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,05178542 0,06438187 ! cytokine production GO:0001816 44 32 0,000 0,05178542 0,06434709 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,05178542 0,06431234 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,05178542 0,06427764 ! vesicle localization GO:0051648 47 32 0,000 0,05178542 0,06424297 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,05336125 0,06616219 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,05336125 0,06612654 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,05336125 0,06609093 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,05336125 0,06605536 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,05336125 0,06601983 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,05336125 0,06598434 ! sister chromatid segregation GO:0000819 46 33 0,000 0,05336125 0,06594888 ! ear morphogenesis GO:0042471 42 33 0,000 0,05336125 0,06591346 ! actomyosin structure organization GO:0031032 43 33 0,000 0,05336125 0,06587808 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,05336125 0,06584274 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,05336125 0,06580743 ! nucleus organization GO:0006997 49 33 0,000 0,05336125 0,06577217 ! female gonad development GO:0008585 49 33 0,000 0,05336125 0,06573694 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,05336125 0,06570175 ! positive regulation of cell development GO:0010720 54 33 0,000 0,05336125 0,06566659 ! lipid homeostasis GO:0055088 55 33 0,000 0,05336125 0,06563148 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,05336125 0,0655964 ! regulation of proteolysis GO:0030162 50 33 0,000 0,05336125 0,06556136 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,05336125 0,06552636 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,05336125 0,06549139 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,05336125 0,06545646 ! cytokinesis GO:0000910 52 33 0,000 0,05336125 0,06542157 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,05336125 0,06538672 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,05493455 0,06727873 ! mRNA catabolic process GO:0006402 48 34 0,000 0,05493455 0,06724293 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,05493455 0,06720716 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,05493455 0,06717143 ! feeding behavior GO:0007631 45 34 0,000 0,05493455 0,06713574 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,05493455 0,06710008 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,05493455 0,06706447 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,05493455 0,06702889 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,05493455 0,06699335 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,05493455 0,06695785 ! neuron migration GO:0001764 46 34 0,000 0,05493455 0,06692238 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,05493455 0,06688695 ! female gamete generation GO:0007292 43 34 0,000 0,05493455 0,06685156 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,05493455 0,06681621 ! polyol metabolic process GO:0019751 44 34 0,000 0,05493455 0,0667809 ! aerobic respiration GO:0009060 47 34 0,000 0,05493455 0,06674562 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,05493455 0,06671038 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,05493455 0,06667518 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,05493455 0,06664001 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,05650532 0,06850935 ! Notch signaling pathway GO:0007219 56 35 0,000 0,05650532 0,06847326 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,05650532 0,0684372 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,05650532 0,06840118 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,05650532 0,0683652 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,05650532 0,06832925 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,05650532 0,06829335 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,05650532 0,06825748 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,05650532 0,06822165 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,05650532 0,06818586 ! glycogen metabolic process GO:0005977 48 35 0,000 0,05650532 0,0681501 ! pigment metabolic process GO:0042440 61 35 0,000 0,05650532 0,06811438 ! protein homooligomerization GO:0051260 52 35 0,000 0,05650532 0,0680787 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,05807358 0,06993153 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,05807358 0,06989494 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,05807358 0,06985838 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,05807358 0,06982187 ! negative regulation of binding GO:0051100 58 36 0,000 0,05807358 0,06978539 ! organic ether metabolic process GO:0018904 46 36 0,000 0,05807358 0,06974894 ! neural tube development GO:0021915 50 36 0,000 0,05807358 0,06971254 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,05807358 0,06967618 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,05807358 0,06963985 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,05807358 0,06960356 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,05807358 0,06956731 ! glucan metabolic process GO:0044042 49 36 0,000 0,05807358 0,06953109 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,05963932 0,07136859 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,05963932 0,07133147 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,05963932 0,0712944 ! ion transmembrane transport GO:0034220 56 37 0,000 0,05963932 0,07125736 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,05963932 0,07122037 ! regulation of protein secretion GO:0050708 51 37 0,000 0,05963932 0,07118341 ! amino acid activation GO:0043038 52 37 0,000 0,05963932 0,07114649 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,05963932 0,0711096 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,06120254 0,07293567 ! gliogenesis GO:0042063 71 38 0,000 0,06120254 0,0728979 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,06120254 0,07286017 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,06120254 0,07282247 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,06120254 0,07278482 ! phagocytosis GO:0006909 60 38 0,000 0,06120254 0,07274721 ! pigmentation GO:0043473 74 38 0,000 0,06120254 0,07270963 ! maintenance of location in cell GO:0051651 69 38 0,000 0,06120254 0,07267209 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,06276326 0,07448684 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,06276326 0,07444842 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,06276326 0,07441005 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,06276326 0,07437171 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,06276326 0,07433341 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,06276326 0,07429516 ! male sex differentiation GO:0046661 53 39 0,000 0,06276326 0,07425694 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,06276326 0,07421876 ! chromatin remodeling GO:0006338 68 39 0,000 0,06276326 0,07418062 ! JNK cascade GO:0007254 54 39 0,000 0,06276326 0,07414252 ! developmental growth GO:0048589 62 39 0,000 0,06276326 0,07410446 ! cell growth GO:0016049 61 39 0,000 0,06276326 0,07406644 ! synapse organization GO:0050808 55 39 0,000 0,06276326 0,07402846 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,06432147 0,07582746 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,06432147 0,07578861 ! regulation of tube size GO:0035150 60 40 0,000 0,06432147 0,07574981 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,06432147 0,07571104 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,06432147 0,07567231 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,06432147 0,07563363 ! peptide metabolic process GO:0006518 56 40 0,000 0,06432147 0,07559498 ! inner ear development GO:0048839 57 40 0,000 0,06432147 0,07555637 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,06432147 0,0755178 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,06432147 0,07547927 ! double-strand break repair GO:0006302 67 40 0,000 0,06432147 0,07544078 ! B cell differentiation GO:0030183 62 40 0,000 0,06432147 0,07540233 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,06432147 0,07536392 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,06432147 0,07532555 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,06587718 0,07710814 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,06587718 0,07706892 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,06587718 0,07702974 ! glucose transport GO:0015758 52 41 0,000 0,06587718 0,0769906 ! endosome transport GO:0016197 71 41 0,000 0,06587718 0,0769515 ! striated muscle contraction GO:0006941 62 41 0,000 0,06587718 0,07691244 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,06587718 0,07687342 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,06587718 0,07683443 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,06587718 0,07679549 ! biopolymer methylation GO:0043414 62 41 0,000 0,06587718 0,07675659 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,06587718 0,07671772 ! mitochondrial transport GO:0006839 60 42 0,000 0,06743039 0,07848679 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,06743039 0,07844709 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,06743039 0,07840743 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,06743039 0,07836781 ! cellular component disassembly GO:0022411 64 42 0,000 0,06743039 0,07832823 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,06743039 0,07828869 ! hexose transport GO:0008645 54 42 0,000 0,06743039 0,07824919 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,06743039 0,07820973 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,06743039 0,07817031 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,06743039 0,07813093 ! excretion GO:0007588 63 42 0,000 0,06743039 0,07809159 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,06743039 0,07805229 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,06743039 0,07801302 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,06743039 0,0779738 ! regulation of cell shape GO:0008360 78 42 0,000 0,06743039 0,07793462 ! positive regulation of binding GO:0051099 59 43 0,000 0,06898111 0,07968686 ! leukocyte migration GO:0050900 60 43 0,000 0,06898111 0,07964686 ! neuromuscular process GO:0050905 79 43 0,000 0,06898111 0,0796069 ! activation of caspase activity GO:0006919 65 43 0,000 0,06898111 0,07956697 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,06898111 0,07952709 ! tRNA processing GO:0008033 49 43 0,000 0,06898111 0,07948725 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,06898111 0,07944744 ! response to insulin stimulus GO:0032868 63 43 0,000 0,06898111 0,07940768 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,06898111 0,07936795 ! methylation GO:0032259 64 43 0,000 0,06898111 0,07932827 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,07052933 0,0810682 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,07052933 0,08102771 ! regulation of action potential GO:0001508 71 44 0,000 0,07052933 0,08098725 ! regulation of ion transport GO:0043269 57 44 0,000 0,07052933 0,08094684 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,07052933 0,08090647 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,07052933 0,08086613 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,07052933 0,08082584 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,07052933 0,08078559 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,07052933 0,08074538 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,07052933 0,08070521 ! RNA catabolic process GO:0006401 64 45 0,000 0,07207508 0,08243296 ! positive regulation of defense response GO:0031349 59 45 0,000 0,07207508 0,08239198 ! regulation of translational initiation GO:0006446 64 45 0,000 0,07207508 0,08235105 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,07207508 0,08231017 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,07207508 0,08226932 ! cell recognition GO:0008037 58 45 0,000 0,07207508 0,08222851 ! cell maturation GO:0048469 60 45 0,000 0,07207508 0,08218774 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,07361834 0,08390593 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,07361834 0,08386437 ! cell redox homeostasis GO:0045454 63 46 0,000 0,07361834 0,08382286 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,07361834 0,08378138 ! regulation of ossification GO:0030278 71 46 0,000 0,07361834 0,08373995 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,07361834 0,08369855 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,07515912 0,08540809 ! viral infectious cycle GO:0019058 71 47 0,000 0,07515912 0,08536591 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,07515912 0,08532378 ! endocrine system development GO:0035270 83 47 0,000 0,07515912 0,08528168 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,07515912 0,08523963 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,07515912 0,08519762 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,07515912 0,08515565 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,07515912 0,08511372 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,07515912 0,08507183 ! chloride transport GO:0006821 67 48 0,000 0,07669742 0,08677033 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,07669742 0,08672767 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,07669742 0,08668505 ! response to temperature stimulus GO:0009266 62 48 0,000 0,07669742 0,08664247 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,07669742 0,08659994 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,07669742 0,08655745 ! gastrulation GO:0007369 73 48 0,000 0,07669742 0,086515 ! regulation of DNA replication GO:0006275 75 48 0,000 0,07669742 0,08647259 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,07669742 0,08643022 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,07669742 0,08638789 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,07669742 0,08634561 ! regulation of endocytosis GO:0030100 63 48 0,000 0,07669742 0,08630336 ! nuclear export GO:0051168 69 48 0,000 0,07669742 0,08626116 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,07669742 0,086219 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,07823326 0,08790254 ! sensory perception of smell GO:0007608 61 49 0,000 0,07823326 0,08785962 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,07823326 0,08781674 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,07823326 0,0877739 ! RNA elongation GO:0006354 62 49 0,000 0,07823326 0,08773111 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,07823326 0,08768835 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,07823326 0,08764564 ! germ cell development GO:0007281 68 49 0,000 0,07823326 0,08760297 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,07823326 0,08756034 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,07823326 0,08751775 ! maintenance of location GO:0051235 84 49 0,000 0,07823326 0,08747521 ! regulation of actin filament length GO:0030832 72 50 0,000 0,07976663 0,08914638 ! ear development GO:0043583 72 50 0,000 0,07976663 0,08910308 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,07976663 0,08905983 ! membrane fusion GO:0006944 80 50 0,000 0,07976663 0,08901662 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,07976663 0,08897345 ! lipid modification GO:0030258 73 50 0,000 0,07976663 0,08893032 ! positive regulation of growth GO:0045927 67 50 0,000 0,07976663 0,08888723 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,07976663 0,08884419 ! proton transport GO:0015992 75 50 0,000 0,07976663 0,08880119 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,07976663 0,08875822 ! positive regulation of secretion GO:0051047 71 51 0,000 0,08129754 0,09041796 ! hydrogen transport GO:0006818 77 51 0,000 0,08129754 0,09037426 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,08129754 0,0903306 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,08129754 0,09028698 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,08129754 0,09024341 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,08129754 0,09019987 ! adult behavior GO:0030534 80 51 0,000 0,08129754 0,09015638 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,08129754 0,09011293 ! transition metal ion transport GO:0000041 74 52 0,000 0,08282598 0,09176289 ! regulation of cellular component size GO:0032535 74 52 0,000 0,08282598 0,09171871 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,08282598 0,09167457 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,08282598 0,09163048 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,08282598 0,09158643 ! establishment of organelle localization GO:0051656 85 52 0,000 0,08282598 0,09154241 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,08435198 0,09318422 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,08435198 0,09313949 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,08435198 0,09309479 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,08435198 0,09305014 ! kidney development GO:0001822 90 53 0,000 0,08435198 0,09300554 ! single fertilization GO:0007338 59 53 0,000 0,08435198 0,09296097 ! amino acid transport GO:0006865 84 54 0,000 0,08587552 0,09459468 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,08587552 0,0945494 ! regulation of mitosis GO:0007088 84 54 0,000 0,08587552 0,09450416 GO:0051783|regulation of nuclear division, ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,08587552 0,09445896 ! DNA catabolic process GO:0006308 67 54 0,000 0,08587552 0,09441381 ! detection of external stimulus GO:0009581 66 54 0,000 0,08587552 0,0943687 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,08587552 0,09432363 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,08587552 0,09427861 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,08587552 0,09423363 ! exocytosis GO:0006887 74 55 0,000 0,08739661 0,09585704 ! mesoderm development GO:0007498 76 55 0,000 0,08739661 0,09581135 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,08739661 0,0957657 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,08739661 0,0957201 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,08891526 0,09733703 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,08891526 0,09729072 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,08891526 0,09724446 ! carbohydrate transport GO:0008643 74 57 0,000 0,09043147 0,09885569 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,09043147 0,09880873 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,09043147 0,09876181 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,09043147 0,09871494 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,09043147 0,09866811 ! camera-type eye development GO:0043010 88 57 0,000 0,09043147 0,09862133 ! secondary metabolic process GO:0019748 84 57 0,000 0,09043147 0,09857459 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,09043147 0,09852789 ! developmental maturation GO:0021700 75 57 0,000 0,09043147 0,09848124 ! gonad development GO:0008406 79 57 0,000 0,09043147 0,09843463 ! viral reproductive process GO:0022415 87 58 0,000 0,09194524 0,10003503 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,09194524 0,09998773 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,09194524 0,09994048 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,09194524 0,09989327 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,09345658 0,10148732 ! activation of MAPK activity GO:0000187 84 59 0,000 0,09345658 0,10143942 ! lung development GO:0030324 94 59 0,000 0,09345658 0,10139157 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,09345658 0,10134377 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,09345658 0,10129601 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,09496549 0,10288301 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,09496549 0,10283457 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,09496549 0,10278618 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,09496549 0,10273783 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,09496549 0,10268953 ! regulation of heart contraction GO:0008016 91 60 0,000 0,09496549 0,10264128 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,09496549 0,10259306 ! fertilization GO:0009566 68 60 0,000 0,09496549 0,1025449 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,09647198 0,10412274 ! meiosis GO:0007126 96 61 0,000 0,09647198 0,1040739 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,09647198 0,10402511 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,09647198 0,10397636 ! urogenital system development GO:0001655 101 61 0,000 0,09647198 0,10392766 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,09647198 0,103879 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,09647198 0,10383039 ! extracellular matrix organization GO:0030198 103 61 0,000 0,09647198 0,10378183 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,09647198 0,10373331 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,09797604 0,10530136 ! neurotransmitter transport GO:0006836 81 62 0,000 0,09797604 0,10525217 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,09797604 0,10520303 ! respiratory tube development GO:0030323 99 62 0,000 0,09797604 0,10515394 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,09797604 0,1051049 ! meiotic cell cycle GO:0051321 97 62 0,000 0,09797604 0,1050559 ! organelle localization GO:0051640 96 62 0,000 0,09797604 0,10500694 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,09947769 0,10656669 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,09947769 0,10651708 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,09947769 0,10646751 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,09947769 0,10641799 ! viral reproduction GO:0016032 92 63 0,000 0,09947769 0,10636852 ! regulation of lipase activity GO:0060191 109 63 0,000 0,09947769 0,10631909 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,10097692 0,10787131 ! appendage morphogenesis GO:0035107 93 64 0,000 0,10097692 0,10782123 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,10097692 0,1077712 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,10097692 0,10772121 ! respiratory system development GO:0060541 100 64 0,000 0,10097692 0,10767127 ! adaptive immune response GO:0002250 94 64 0,000 0,10097692 0,10762137 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,10247375 0,1091661 ! regulation of caspase activity GO:0043281 97 65 0,000 0,10247375 0,10911556 ! appendage development GO:0048736 94 65 0,000 0,10247375 0,10906507 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,10247375 0,10901463 ! defense response to bacterium GO:0042742 73 65 0,000 0,10247375 0,10896423 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,10247375 0,10891387 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,10247375 0,10886357 ! activation of immune response GO:0002253 83 65 0,000 0,10247375 0,10881331 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,10396816 0,11034923 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,10396816 0,11029833 ! antigen processing and presentation GO:0019882 96 66 0,000 0,10396816 0,11024748 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,10396816 0,11019667 ! regulation of immune effector process GO:0002697 101 66 0,000 0,10396816 0,11014591 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,10546018 0,11167514 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,10546018 0,11162375 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,10546018 0,11157241 ! acute inflammatory response GO:0002526 92 68 0,000 0,10694979 0,11309633 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,10694979 0,11304436 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,10694979 0,11299243 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,10694979 0,11294055 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,10694979 0,11288872 ! rhythmic process GO:0048511 105 68 0,000 0,10694979 0,11283694 ! inorganic anion transport GO:0015698 93 68 0,000 0,10694979 0,1127852 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,10843702 0,11430116 ! response to drug GO:0042493 108 69 0,000 0,10843702 0,1142488 ! humoral immune response GO:0006959 86 70 0,000 0,10992184 0,11576018 ! amine transport GO:0015837 101 70 0,000 0,10992184 0,1157072 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,10992184 0,11565427 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,11140429 0,11716043 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,11140429 0,11710688 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,11140429 0,11705338 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,11140429 0,11699993 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,11288434 0,11850022 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,11288434 0,11844616 ! negative regulation of transport GO:0051051 116 73 0,000 0,11436202 0,11994193 ! regulation of blood pressure GO:0008217 107 73 0,000 0,11436202 0,11988726 ! tube morphogenesis GO:0035239 118 73 0,000 0,11436202 0,11983264 ! mitochondrion organization GO:0007005 104 73 0,000 0,11436202 0,11977807 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,11436202 0,11972355 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,11583732 0,12121285 ! digestion GO:0007586 97 74 0,000 0,11583732 0,12115772 ! protein import into nucleus GO:0006606 118 74 0,000 0,11583732 0,12110265 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,11583732 0,12104763 ! blood coagulation GO:0007596 116 75 0,000 0,11731025 0,12253114 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 0,000 0,11731025 0,12247552 ! nuclear import GO:0051170 121 75 0,000 0,11731025 0,12241995 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,11731025 0,12236443 ! amine biosynthetic process GO:0009309 97 76 0,000 0,1187808 0,12384218 ! tRNA metabolic process GO:0006399 95 76 0,000 0,1187808 0,12378607 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,1187808 0,12373 ! regulation of protein transport GO:0051223 114 76 0,000 0,1187808 0,12367399 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,120249 0,12514602 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,120249 0,12508941 ! regulation of DNA binding GO:0051101 119 77 0,000 0,120249 0,12503286 ! gland development GO:0048732 148 77 0,000 0,120249 0,12497636 ! sex differentiation GO:0007548 105 77 0,000 0,120249 0,12491992 ! protein ubiquitination GO:0016567 125 77 0,000 0,120249 0,12486352 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,120249 0,12480717 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,120249 0,12475088 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,12171483 0,12621465 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,12171483 0,12615778 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,1231783 0,12761716 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,1231783 0,1275597 ! T cell activation GO:0042110 134 79 0,000 0,1231783 0,12750229 ! regulation of lyase activity GO:0051339 133 79 0,000 0,1231783 0,12744493 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,1231783 0,12738763 ! chromatin assembly GO:0031497 102 80 0,000 0,12463942 0,12884075 GO:0006334|nucleosome assembly, ! protein localization in nucleus GO:0034504 133 80 0,000 0,12463942 0,12878287 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,12463942 0,12872504 ! forebrain development GO:0030900 131 80 0,000 0,12463942 0,12866726 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,12609818 0,13011477 ! hemostasis GO:0007599 125 81 0,000 0,12609818 0,13005642 ! mRNA transport GO:0051028 121 81 0,000 0,12609818 0,12999813 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,12609818 0,12993988 ! vitamin metabolic process GO:0006766 103 81 0,000 0,12609818 0,12988169 ! ossification GO:0001503 134 82 0,000 0,1275546 0,131323 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,1275546 0,13126425 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,12900868 0,13270124 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,12900868 0,13264191 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,12900868 0,13258265 ! regulation of defense response GO:0031347 117 84 0,000 0,13046041 0,13401472 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,13046041 0,13395489 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,13046041 0,13389512 ! sterol metabolic process GO:0016125 120 84 0,000 0,13046041 0,13383539 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,13190981 0,13526196 ! rRNA metabolic process GO:0016072 107 85 0,000 0,13190981 0,13520168 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,13190981 0,13514146 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,13190981 0,13508129 ! regulation of protein localization GO:0032880 132 85 0,000 0,13190981 0,13502117 ! regulation of membrane potential GO:0042391 128 85 0,000 0,13190981 0,13496111 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,13190981 0,1349011 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,13335688 0,13632037 ! nucleosome organization GO:0034728 114 87 0,000 0,13480162 0,13773599 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,13480162 0,13767483 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,13480162 0,13761372 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,13480162 0,13755267 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,13480162 0,13749167 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,13480162 0,13743073 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,13624403 0,13883973 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,13624403 0,13877824 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,13624403 0,13871681 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,13624403 0,13865543 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,13768412 0,14005903 ! reproductive developmental process GO:0003006 127 89 0,000 0,13768412 0,13999712 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,13768412 0,13993525 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,13768412 0,13987344 ! regulation of T cell activation GO:0050863 128 89 0,000 0,13768412 0,13981169 ! leukocyte differentiation GO:0002521 143 90 0,000 0,13912189 0,14120933 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,13912189 0,14114704 ! hormone metabolic process GO:0042445 121 90 0,000 0,13912189 0,14108481 ! RNA localization GO:0006403 135 91 0,000 0,14055735 0,1424777 ! ATP metabolic process GO:0046034 137 91 0,000 0,14055735 0,14241493 ! response to virus GO:0009615 122 91 0,000 0,14055735 0,14235222 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,14199049 0,14374038 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,14199049 0,14367714 ! cell fate commitment GO:0045165 141 92 0,000 0,14199049 0,14361396 ! positive regulation of immune response GO:0050778 121 92 0,000 0,14199049 0,14355083 ! DNA recombination GO:0006310 146 92 0,000 0,14199049 0,14348776 ! sulfur metabolic process GO:0006790 118 92 0,000 0,14199049 0,14342474 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,14342133 0,14480644 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,14342133 0,1447429 ! electron transport chain GO:0022900 123 94 0,000 0,14484987 0,14612048 ! regulation of binding GO:0051098 151 95 0,000 0,1462761 0,14749453 ! angiogenesis GO:0001525 149 95 0,000 0,1462761 0,1474299 ! carboxylic acid transport GO:0046942 147 95 0,000 0,1462761 0,14736532 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,14770004 0,14873471 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,14770004 0,14866962 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,14770004 0,14860459 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,14770004 0,14853961 ! protein maturation GO:0051604 129 96 0,000 0,14770004 0,14847469 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,14912168 0,1498383 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,1519581 0,15262168 ! extracellular structure organization GO:0043062 156 99 0,000 0,1519581 0,15255506 ! protein import GO:0017038 156 99 0,000 0,1519581 0,1524885 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,1519581 0,152422 ! regulation of translation GO:0006417 151 100 0,000 0,15337289 0,15377404 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,15337289 0,15370703 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,15337289 0,15364009 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,15337289 0,1535732 ! divalent metal ion transport GO:0070838 171 100 0,000 0,15337289 0,15350637 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,15337289 0,1534396 ! protein localization in organelle GO:0033365 161 100 0,000 0,15337289 0,15337289