pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/3420-4-real-Zhou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL4685_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! autophagic vacuole formation GO:0000045 12 7 2,000 5,387E-08 1,278E-04 ! macroautophagy GO:0016236 14 8 2,000 8,612E-08 1,022E-04 ! cellular response to starvation GO:0009267 26 16 2,000 8,558E-07 6,769E-04 ! cellular response to nutrient levels GO:0031669 32 20 2,000 1,737E-06 1,03E-03 ! response to starvation GO:0042594 35 21 2,000 2,024E-06 9,608E-04 ! cellular response to extracellular stimulus GO:0031668 37 23 2,000 2,691E-06 1,064E-03 ! autophagy GO:0006914 36 27 2,000 4,431E-06 1,502E-03 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 2,087E-05 6,192E-03 ! vesicle organization GO:0016050 87 48 2,000 2,577E-05 6,795E-03 ! cytoplasmic sequestering of transcription factor GO:0042994 12 9 1,000 4,998E-05 0,01186141 ! cytoplasmic sequestering of protein GO:0051220 15 10 1,000 6,244E-05 0,01346894 ! negative regulation of transcription factor import into nucleus GO:0042992 26 13 1,000 1,08E-04 0,02135335 ! negative regulation of protein import into nucleus GO:0042308 27 14 1,000 1,259E-04 0,02297897 ! cellular respiration GO:0045333 119 85 2,000 1,429E-04 0,02422399 ! induction of apoptosis via death domain receptors GO:0008625 19 15 1,000 1,451E-04 0,02296203 ! negative regulation of nucleocytoplasmic transport GO:0046823 29 16 1,000 1,658E-04 0,02458404 ! axis specification GO:0009798 26 16 1,000 1,658E-04 0,02313792 ! DNA fragmentation involved in apoptosis GO:0006309 20 16 1,000 1,658E-04 0,02185248 ! zinc ion transport GO:0006829 22 17 1,000 1,877E-04 0,02344537 ! negative regulation of intracellular transport GO:0032387 31 18 1,000 2,11E-04 0,02503878 ! cell structure disassembly during apoptosis GO:0006921 25 20 1,000 2,617E-04 0,02956962 ! activation of JUN kinase activity GO:0007257 28 20 1,000 2,617E-04 0,02822555 ! apoptotic nuclear changes GO:0030262 31 21 1,000 2,89E-04 0,02981829 ! negative regulation of Wnt receptor signaling pathway GO:0030178 32 21 1,000 2,89E-04 0,02857586 ! DNA catabolic process, endonucleolytic GO:0000737 27 22 1,000 3,177E-04 0,03015388 ! regulation of transcription factor import into nucleus GO:0042990 49 24 1,000 3,79E-04 0,0345913 ! positive regulation of JUN kinase activity GO:0043507 33 24 1,000 3,79E-04 0,03331014 ! activation of pro-apoptotic gene products GO:0008633 44 25 1,000 4,117E-04 0,03488786 ! protein amino acid alkylation GO:0008213 40 26 1,000 4,456E-04 0,03646502 GO:0006479|protein amino acid methylation, ! acetyl-CoA catabolic process GO:0046356 38 26 1,000 4,456E-04 0,03524951 GO:0006099|tricarboxylic acid cycle, ! regulation of JUN kinase activity GO:0043506 39 26 1,000 4,456E-04 0,03411243 ! coenzyme catabolic process GO:0009109 40 27 1,000 4,809E-04 0,03566385 ! acetyl-CoA metabolic process GO:0006084 42 28 1,000 5,175E-04 0,03721593 ! regulation of protein import into nucleus GO:0042306 56 30 1,000 5,947E-04 0,04150701 ! negative regulation of protein transport GO:0051224 53 30 1,000 5,947E-04 0,0403211 ! response to heat GO:0009408 43 30 1,000 5,947E-04 0,03920107 ! cofactor catabolic process GO:0051187 52 32 1,000 6,771E-04 0,04342614 ! maintenance of protein location in cell GO:0032507 66 33 1,000 7,203E-04 0,04497816 ! negative regulation of DNA binding GO:0043392 54 34 1,000 7,647E-04 0,04652965 ! regulation of Wnt receptor signaling pathway GO:0030111 57 34 1,000 7,647E-04 0,04536641 ! regulation of intracellular protein transport GO:0033157 64 36 1,000 8,575E-04 0,04963048 ! dorsal/ventral pattern formation GO:0009953 50 36 1,000 8,575E-04 0,0484488 ! negative regulation of binding GO:0051100 59 37 1,000 9,058E-04 0,04998938 ! nucleus organization GO:0006997 58 37 1,000 9,058E-04 0,04885326 ! maintenance of protein location GO:0045185 72 38 1,000 9,555E-04 0,05038427 ! aerobic respiration GO:0009060 56 39 1,000 1,006E-03 0,05191499 ! maintenance of location in cell GO:0051651 77 41 1,000 1,112E-03 0,05614471 ! regulation of nucleocytoplasmic transport GO:0046822 75 42 1,000 1,167E-03 0,0576813 ! cellular component disassembly GO:0022411 66 44 1,000 1,28E-03 0,06199101 ! biopolymer methylation GO:0043414 67 44 1,000 1,28E-03 0,06075119 ! JNK cascade GO:0007254 66 44 1,000 1,28E-03 0,05955999 ! stress-activated protein kinase signaling pathway GO:0031098 69 45 1,000 1,339E-03 0,06108658 ! regulation of translational initiation GO:0006446 70 46 1,000 1,398E-03 0,06261218 ! activation of caspase activity GO:0006919 70 46 1,000 1,398E-03 0,06145269 ! regulation of JNK cascade GO:0046328 72 47 1,000 1,459E-03 0,06297058 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 75 48 1,000 1,522E-03 0,06448759 ! induction of apoptosis by extracellular signals GO:0008624 96 49 1,000 1,585E-03 0,06600364 ! response to temperature stimulus GO:0009266 66 49 1,000 1,585E-03 0,06486565 ! regulation of intracellular transport GO:0032386 83 49 1,000 1,585E-03 0,06376623 ! methylation GO:0032259 74 49 1,000 1,585E-03 0,06270346 ! positive regulation of caspase activity GO:0043280 77 51 1,000 1,716E-03 0,06676927 GO:0010952|positive regulation of peptidase activity, ! transition metal ion transport GO:0000041 88 53 1,000 1,852E-03 0,07089485 ! maintenance of location GO:0051235 94 53 1,000 1,852E-03 0,06976953 ! DNA catabolic process GO:0006308 71 56 1,000 2,065E-03 0,07658424 ! activation of MAPK activity GO:0000187 95 62 1,000 2,525E-03 0,092185 ! regulation of cellular response to stress GO:0080135 100 67 1,000 2,942E-03 0,10576215 ! regulation of caspase activity GO:0043281 104 68 1,000 3,028E-03 0,10726181 ! regulation of endopeptidase activity GO:0052548 106 70 1,000 3,206E-03 0,11187574 ! regulation of MAPKKK cascade GO:0043408 123 73 1,000 3,481E-03 0,11971439 ! regulation of peptidase activity GO:0052547 113 75 1,000 3,67E-03 0,12442188 ! negative regulation of transport GO:0051051 122 77 1,000 3,864E-03 0,1291545 ! regulation of DNA binding GO:0051101 130 80 1,000 4,164E-03 0,13724323 ! response to unfolded protein GO:0006986 113 80 1,000 4,164E-03 0,13536319 ! regulation of protein transport GO:0051223 123 81 1,000 4,266E-03 0,13681402 GO:0070201|regulation of establishment of protein localization, ! response to protein stimulus GO:0051789 127 85 1,000 4,687E-03 0,14830244 ! one-carbon metabolic process GO:0006730 126 85 1,000 4,687E-03 0,14635109 ! regulation of protein localization GO:0032880 141 90 1,000 5,239E-03 0,16145764 ! positive regulation of MAP kinase activity GO:0043406 143 93 1,000 5,584E-03 0,16987774 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 6,02E-03 0,18082404 ! positive regulation of protein ubiquitination GO:0031398 8 5 0,000 6,02E-03 0,17856374 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 6,02E-03 0,17635925 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 5 0,000 6,02E-03 0,17420853 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 6,02E-03 0,17210963 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! negative regulation of tyrosine phosphorylation of Stat3 protein GO:0042518 13 5 0,000 6,02E-03 0,17006071 GO:0042532|negative regulation of tyrosine phosphorylation of STAT protein, ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,02E-03 0,16805999 ! regulation of cGMP biosynthetic process GO:0030826 7 5 0,000 6,02E-03 0,16610581 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 6,02E-03 0,16419655 ! positive regulation of actin filament polymerization GO:0030838 8 5 0,000 6,02E-03 0,16233068 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 7 5 0,000 6,02E-03 0,16050674 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 6,02E-03 0,15872333 ! response to oxygen radical GO:0000305 11 5 0,000 6,02E-03 0,15697912 ! negative regulation of bone resorption GO:0045779 11 5 0,000 6,02E-03 0,15527282 ! myoblast cell fate commitment GO:0048625 8 5 0,000 6,02E-03 0,15360322 ! nucleotide-sugar transport GO:0015780 8 5 0,000 6,02E-03 0,15196914 ! positive regulation of lipid biosynthetic process GO:0046889 7 5 0,000 6,02E-03 0,15036947 ! regulation of interferon-beta production GO:0032648 5 5 0,000 6,02E-03 0,14880312 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 6 5 0,000 6,02E-03 0,14726907 GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 6 5 0,000 6,02E-03 0,14576632 ! female meiosis GO:0007143 8 5 0,000 6,02E-03 0,14429393 ! nose development GO:0043584 10 5 0,000 6,02E-03 0,14285099 ! DNA catabolic process, exonucleolytic GO:0000738 7 5 0,000 6,02E-03 0,14143663 ! regulation of cell adhesion mediated by integrin GO:0033628 15 5 0,000 6,02E-03 0,14005 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 6,02E-03 0,13869029 ! short-chain fatty acid metabolic process GO:0046459 8 5 0,000 6,02E-03 0,13735673 ! tryptophanyl-tRNA aminoacylation GO:0006436 6 5 0,000 6,02E-03 0,13604857 ! cobalt ion transport GO:0006824 9 5 0,000 6,02E-03 0,13476509 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 6,02E-03 0,1335056 ! SMAD protein complex assembly GO:0007183 10 5 0,000 6,02E-03 0,13226944 ! phospholipid dephosphorylation GO:0046839 7 5 0,000 6,02E-03 0,13105596 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 6,02E-03 0,12986454 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 6,02E-03 0,12869459 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 6,02E-03 0,12754553 ! adaptation of signaling pathway GO:0022401 9 5 0,000 6,02E-03 0,12641681 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! cardiac muscle cell proliferation GO:0060038 7 5 0,000 6,02E-03 0,12530789 GO:0014855|striated muscle cell proliferation, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 6,02E-03 0,12421826 ! negative regulation of gene-specific transcription GO:0032582 10 5 0,000 6,02E-03 0,12314741 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 6,02E-03 0,12209487 ! negative regulation of histone modification GO:0031057 7 5 0,000 6,02E-03 0,12106017 ! malate metabolic process GO:0006108 8 5 0,000 6,02E-03 0,12004285 ! positive regulation of histone modification GO:0031058 6 5 0,000 6,02E-03 0,1190425 ! transcription from mitochondrial promoter GO:0006390 8 5 0,000 6,02E-03 0,11805867 ! clathrin coat assembly GO:0048268 11 5 0,000 6,02E-03 0,11709098 ! Notch receptor processing GO:0007220 8 5 0,000 6,02E-03 0,11613902 ! phototransduction, visible light GO:0007603 7 5 0,000 6,02E-03 0,11520242 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,02E-03 0,1142808 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 6,02E-03 0,11337381 ! mating behavior GO:0007617 6 5 0,000 6,02E-03 0,1124811 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 6,02E-03 0,11160234 ! copulation GO:0007620 8 5 0,000 6,02E-03 0,11073721 ! protein maturation by protein folding GO:0022417 13 5 0,000 6,02E-03 0,10988538 ! embryonic hemopoiesis GO:0035162 13 5 0,000 6,02E-03 0,10904656 ! regulation of potassium ion transport GO:0043266 9 5 0,000 6,02E-03 0,10822045 ! apoptotic cell clearance GO:0043277 14 5 0,000 6,02E-03 0,10740676 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 9 5 0,000 6,02E-03 0,10660522 ! lipoprotein particle clearance GO:0034381 9 5 0,000 6,02E-03 0,10581555 ! fructose 1,6-bisphosphate metabolic process GO:0030388 8 5 0,000 6,02E-03 0,1050375 ! regulation of smooth muscle cell apoptosis GO:0034391 8 5 0,000 6,02E-03 0,1042708 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 6,02E-03 0,10351521 GO:0046329|negative regulation of JNK cascade, ! oocyte maturation GO:0001556 6 5 0,000 6,02E-03 0,1027705 ! response to axon injury GO:0048678 8 5 0,000 6,02E-03 0,10203642 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,02E-03 0,10131276 ! response to protozoan GO:0001562 10 5 0,000 6,02E-03 0,10059929 ! negative regulation of heart contraction GO:0045822 12 5 0,000 6,02E-03 0,0998958 ! lymph vessel development GO:0001945 8 5 0,000 6,02E-03 0,09920208 ! regulation of activin receptor signaling pathway GO:0032925 11 5 0,000 6,02E-03 0,09851793 ! endochondral ossification GO:0001958 13 5 0,000 6,02E-03 0,09784315 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 6,02E-03 0,09717755 ! single strand break repair GO:0000012 5 5 0,000 6,02E-03 0,09652094 ! parathyroid gland development GO:0060017 8 5 0,000 6,02E-03 0,09587315 ! anagen GO:0042640 7 5 0,000 6,02E-03 0,095234 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 6,02E-03 0,09460331 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 6,02E-03 0,09398092 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 6,02E-03 0,09336666 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 8 5 0,000 6,02E-03 0,09276039 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 8 5 0,000 6,02E-03 0,09216193 ! smooth muscle tissue development GO:0048745 14 5 0,000 6,02E-03 0,09157115 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,02E-03 0,09098789 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 6,02E-03 0,09041202 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 6,02E-03 0,08984339 ! cardiac muscle fiber development GO:0048739 8 5 0,000 6,02E-03 0,08928187 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,02E-03 0,08872733 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 8 5 0,000 6,02E-03 0,08817963 ! neutrophil mediated immunity GO:0002446 6 5 0,000 6,02E-03 0,08763865 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 6,02E-03 0,08710427 ! regulation of oligodendrocyte differentiation GO:0048713 15 5 0,000 6,02E-03 0,08657636 GO:0048715|negative regulation of oligodendrocyte differentiation, ! mitochondrion localization, microtubule-mediated GO:0034643 9 5 0,000 6,02E-03 0,08605482 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! negative regulation of RNA splicing GO:0033119 6 5 0,000 6,02E-03 0,08553952 ! ionotropic glutamate receptor signaling pathway GO:0035235 10 5 0,000 6,02E-03 0,08503035 ! positive regulation of isotype switching to IgG isotypes GO:0048304 8 5 0,000 6,02E-03 0,08452722 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 6,02E-03 0,08403 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 9 5 0,000 6,02E-03 0,08353859 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 6,02E-03 0,0830529 ! tyrosine catabolic process GO:0006572 7 5 0,000 6,02E-03 0,08257283 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 6,02E-03 0,08209827 ! proline biosynthetic process GO:0006561 6 5 0,000 6,02E-03 0,08162914 ! L-serine biosynthetic process GO:0006564 6 5 0,000 6,02E-03 0,08116534 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 6,02E-03 0,08070678 ! polyol catabolic process GO:0046174 7 5 0,000 6,02E-03 0,08025337 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 6,02E-03 0,07980503 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 6,02E-03 0,07936166 ! sister chromatid cohesion GO:0007062 10 5 0,000 6,02E-03 0,0789232 ! response to ATP GO:0033198 6 5 0,000 6,02E-03 0,07848956 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 9 5 0,000 6,02E-03 0,07806065 ! positive regulation of stress fiber formation GO:0051496 15 5 0,000 6,02E-03 0,07763641 ! neutrophil activation GO:0042119 6 5 0,000 6,02E-03 0,07721675 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 6,02E-03 0,07680161 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 6,02E-03 0,07639091 ! response to food GO:0032094 5 5 0,000 6,02E-03 0,07598457 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 6,02E-03 0,07558254 GO:0043088|regulation of Cdc42 GTPase activity, ! positive regulation of transporter activity GO:0032411 5 5 0,000 6,02E-03 0,07518473 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 8 5 0,000 6,02E-03 0,0747911 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,02E-03 0,07440156 ! paraxial mesoderm development GO:0048339 9 5 0,000 6,02E-03 0,07401606 ! forebrain neuron development GO:0021884 7 5 0,000 6,02E-03 0,07363453 ! melanosome organization GO:0032438 7 5 0,000 6,02E-03 0,07325692 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 6,02E-03 0,07288316 ! virus-infected cell apoptosis GO:0006926 8 5 0,000 6,02E-03 0,0725132 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 6,02E-03 0,07214697 ! positive regulation of neuroblast proliferation GO:0002052 9 5 0,000 6,02E-03 0,07178442 ! mesodermal cell fate determination GO:0007500 7 5 0,000 6,02E-03 0,0714255 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,02E-03 0,07107015 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 8 5 0,000 6,02E-03 0,07071831 ! nucleoside salvage GO:0043174 7 5 0,000 6,02E-03 0,07036995 GO:0006166|purine ribonucleoside salvage, ! lipid glycosylation GO:0030259 6 5 0,000 6,02E-03 0,070025 ! attachment of GPI anchor to protein GO:0016255 10 5 0,000 6,02E-03 0,06968341 ! negative regulation of platelet activation GO:0010544 8 5 0,000 6,02E-03 0,06934514 GO:0010543|regulation of platelet activation, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 6,02E-03 0,06901014 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 6,02E-03 0,06867836 ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 6,02E-03 0,06834976 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of fatty acid metabolic process GO:0045923 6 5 0,000 6,02E-03 0,06802428 ! early endosome to late endosome transport GO:0045022 11 5 0,000 6,02E-03 0,06770189 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 6 5 0,000 6,02E-03 0,06738254 ! depyrimidination GO:0045008 8 5 0,000 6,02E-03 0,06706619 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,02E-03 0,0667528 ! 5S class rRNA transcription GO:0042791 8 5 0,000 6,02E-03 0,06644232 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 5 0,000 6,02E-03 0,06613472 ! neuronal ion channel clustering GO:0045161 8 5 0,000 6,02E-03 0,06582995 ! sodium ion homeostasis GO:0055078 6 5 0,000 6,02E-03 0,06552798 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 6,02E-03 0,06522876 ! monocyte differentiation GO:0030224 7 5 0,000 6,02E-03 0,06493227 ! negative regulation of peptide secretion GO:0002792 8 5 0,000 6,02E-03 0,06463846 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 6 5 0,000 6,02E-03 0,0643473 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 6,02E-03 0,06405874 ! response to UV-C GO:0010225 7 5 0,000 6,02E-03 0,06377277 ! protein targeting to vacuole GO:0006623 6 5 0,000 6,02E-03 0,06348933 ! activated T cell proliferation GO:0050798 7 5 0,000 6,02E-03 0,0632084 ! negative regulation of alpha-beta T cell activation GO:0046636 7 5 0,000 6,02E-03 0,06292995 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! regulation of alpha-beta T cell proliferation GO:0046640 13 5 0,000 6,02E-03 0,06265395 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 6,02E-03 0,06238035 ! regulation of integrin biosynthetic process GO:0045113 9 5 0,000 6,02E-03 0,06210913 ! regulation of killing of cells of another organism GO:0051709 6 5 0,000 6,02E-03 0,06184026 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 6,02E-03 0,0615737 ! lymphoid progenitor cell differentiation GO:0002320 12 5 0,000 6,02E-03 0,06130944 ! positive regulation of T cell cytokine production GO:0002726 9 5 0,000 6,02E-03 0,06104743 GO:0032743|positive regulation of interleukin-2 production, ! L-ascorbic acid metabolic process GO:0019852 7 5 0,000 6,02E-03 0,06078766 ! base-excision repair, DNA ligation GO:0006288 5 5 0,000 6,02E-03 0,06053008 ! response to cadmium ion GO:0046686 8 5 0,000 6,02E-03 0,06027468 ! melanosome transport GO:0032402 8 5 0,000 6,02E-03 0,06002143 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 6,02E-03 0,05977029 ! regulation of acetylcholine secretion GO:0014056 10 5 0,000 6,02E-03 0,05952125 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 6,02E-03 0,05927427 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 6,02E-03 0,05902934 ! positive T cell selection GO:0043368 10 5 0,000 6,02E-03 0,05878642 ! purine deoxyribonucleotide catabolic process GO:0009155 6 5 0,000 6,02E-03 0,05854549 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 6,02E-03 0,05830653 ! regulation of interleukin-1 production GO:0032652 8 5 0,000 6,02E-03 0,05806951 ! ribosomal subunit assembly GO:0042257 5 5 0,000 6,02E-03 0,05783441 ! base conversion or substitution editing GO:0016553 6 5 0,000 6,02E-03 0,05760121 ! regulation of chondrocyte differentiation GO:0032330 9 5 0,000 6,02E-03 0,05736988 ! negative regulation of monooxygenase activity GO:0032769 10 5 0,000 6,02E-03 0,0571404 ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 6,02E-03 0,05691275 ! positive regulation of interleukin-12 production GO:0032735 5 5 0,000 6,02E-03 0,0566869 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 6,02E-03 0,05646284 ! histone demethylation GO:0016577 10 5 0,000 6,02E-03 0,05624055 ! mitotic recombination GO:0006312 10 5 0,000 6,02E-03 0,05602 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 5 0,000 6,02E-03 0,05580117 ! regulation of sterol transport GO:0032371 7 5 0,000 6,02E-03 0,05558404 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 6,02E-03 0,0553686 ! sympathetic nervous system development GO:0048485 13 5 0,000 6,02E-03 0,05515482 ! enteric nervous system development GO:0048484 9 5 0,000 6,02E-03 0,05494269 ! oxygen homeostasis GO:0032364 8 5 0,000 6,02E-03 0,05473218 ! establishment of planar polarity GO:0001736 7 5 0,000 6,02E-03 0,05452328 ! lymphocyte costimulation GO:0031294 12 5 0,000 6,02E-03 0,05431597 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 6 5 0,000 6,02E-03 0,05411023 ! transcription termination GO:0006353 8 5 0,000 6,02E-03 0,05390604 ! plasminogen activation GO:0031639 5 5 0,000 6,02E-03 0,05370338 ! B cell homeostasis GO:0001782 12 5 0,000 6,02E-03 0,05350225 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 6,02E-03 0,05330261 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 6,02E-03 0,05310446 ! regulation of hair follicle development GO:0051797 9 5 0,000 6,02E-03 0,05290778 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 6,02E-03 0,05271254 ! apical protein localization GO:0045176 8 5 0,000 6,02E-03 0,05251875 ! definitive hemopoiesis GO:0060216 5 5 0,000 6,02E-03 0,05232637 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 6,02E-03 0,0521354 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 6,02E-03 0,05194582 ! glucocorticoid biosynthetic process GO:0006704 6 5 0,000 6,02E-03 0,05175761 ! regulation of keratinocyte differentiation GO:0045616 7 5 0,000 6,02E-03 0,05157076 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 6,02E-03 0,05138525 ! regulation of centrosome duplication GO:0010824 6 5 0,000 6,02E-03 0,05120107 ! disaccharide metabolic process GO:0005984 9 5 0,000 6,02E-03 0,05101821 ! galactolipid metabolic process GO:0019374 8 5 0,000 6,02E-03 0,05083665 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 6,02E-03 0,05065638 GO:0033015|tetrapyrrole catabolic process, ! positive regulation of T cell mediated cytotoxicity GO:0001916 11 5 0,000 6,02E-03 0,05047738 ! determination of adult lifespan GO:0008340 8 5 0,000 6,02E-03 0,05029965 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 6,02E-03 0,05012316 ! ectodermal gut morphogenesis GO:0048567 6 5 0,000 6,02E-03 0,0499479 GO:0007439|ectodermal gut development, ! somatic stem cell maintenance GO:0035019 14 5 0,000 6,02E-03 0,04977387 ! T cell activation during immune response GO:0002286 9 5 0,000 6,02E-03 0,04960104 ! negative regulation of fibrinolysis GO:0051918 9 5 0,000 6,02E-03 0,04942941 ! negative regulation of lipase activity GO:0060192 7 5 0,000 6,02E-03 0,04925896 ! establishment of apical/basal cell polarity GO:0035089 7 5 0,000 6,02E-03 0,04908969 ! neural plate development GO:0001840 7 5 0,000 6,02E-03 0,04892157 ! regulation of sensory perception GO:0051931 6 5 0,000 6,02E-03 0,04875461 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 10 5 0,000 6,02E-03 0,04858877 ! regulation of histone acetylation GO:0035065 7 5 0,000 6,02E-03 0,04842407 ! sensory cilium assembly GO:0035058 6 5 0,000 6,02E-03 0,04826047 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 14 5 0,000 6,02E-03 0,04809798 ! diacylglycerol metabolic process GO:0046339 8 5 0,000 6,02E-03 0,04793658 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 6,02E-03 0,04777625 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 11 5 0,000 6,02E-03 0,047617 ! negative regulation of smooth muscle contraction GO:0045986 10 5 0,000 6,02E-03 0,0474588 ! receptor biosynthetic process GO:0032800 6 5 0,000 6,02E-03 0,04730165 ! penetration of zona pellucida GO:0007341 9 5 0,000 6,02E-03 0,04714554 ! drug metabolic process GO:0017144 5 5 0,000 6,02E-03 0,04699046 ! protein amino acid prenylation GO:0018346 9 5 0,000 6,02E-03 0,04683639 ! organ regeneration GO:0031100 7 5 0,000 6,02E-03 0,04668333 ! carnitine metabolic process GO:0009437 5 5 0,000 6,02E-03 0,04653127 GO:0006577|betaine metabolic process, ! regulation of binding GO:0051098 164 99 1,000 6,304E-03 0,04856891 ! electron transport chain GO:0022900 135 99 1,000 6,304E-03 0,04841173 ! tRNA transcription GO:0009304 11 6 0,000 7,22E-03 0,0552652 ! negative regulation of S phase of mitotic cell cycle GO:0045749 13 6 0,000 7,22E-03 0,0550875 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 7,22E-03 0,05491094 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 8 6 0,000 7,22E-03 0,0547355 ! regulation of helicase activity GO:0051095 11 6 0,000 7,22E-03 0,05456119 ! regulation of cGMP metabolic process GO:0030823 8 6 0,000 7,22E-03 0,05438798 ! sleep GO:0030431 13 6 0,000 7,22E-03 0,05421586 ! positive regulation of axon extension GO:0045773 10 6 0,000 7,22E-03 0,05404484 ! negative regulation of small GTPase mediated signal transduction GO:0051058 11 6 0,000 7,22E-03 0,05387488 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 7,22E-03 0,053706 ! forebrain regionalization GO:0021871 7 6 0,000 7,22E-03 0,05353817 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 7,22E-03 0,05337138 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 7,22E-03 0,05320563 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 7,22E-03 0,05304091 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 7,22E-03 0,0528772 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 18 6 0,000 7,22E-03 0,0527145 ! regulation of protein export from nucleus GO:0046825 8 6 0,000 7,22E-03 0,0525528 ! neuron adhesion GO:0007158 9 6 0,000 7,22E-03 0,05239209 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 7,22E-03 0,05223236 ! signal peptide processing GO:0006465 8 6 0,000 7,22E-03 0,0520736 ! embryonic camera-type eye development GO:0031076 11 6 0,000 7,22E-03 0,0519158 GO:0048596|embryonic camera-type eye morphogenesis, ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 7,22E-03 0,05175895 ! glucocorticoid receptor signaling pathway GO:0042921 11 6 0,000 7,22E-03 0,05160305 GO:0031958|corticosteroid receptor signaling pathway, ! citrate metabolic process GO:0006101 10 6 0,000 7,22E-03 0,05144809 ! fibril organization GO:0043206 13 6 0,000 7,22E-03 0,05129405 ! regulation of mitochondrial membrane permeability GO:0046902 12 6 0,000 7,22E-03 0,05114093 ! neurofilament cytoskeleton organization GO:0060052 10 6 0,000 7,22E-03 0,05098873 ! posttranscriptional gene silencing by RNA GO:0035194 14 6 0,000 7,22E-03 0,05083743 GO:0016441|posttranscriptional gene silencing, ! behavioral response to pain GO:0048266 10 6 0,000 7,22E-03 0,05068702 ! protein refolding GO:0042026 13 6 0,000 7,22E-03 0,0505375 ! metabotropic glutamate receptor signaling pathway GO:0007216 8 6 0,000 7,22E-03 0,05038886 ! rhythmic behavior GO:0007622 14 6 0,000 7,22E-03 0,05024109 ! glial cell fate commitment GO:0021781 17 6 0,000 7,22E-03 0,05009419 ! erythrocyte maturation GO:0043249 7 6 0,000 7,22E-03 0,04994814 ! sensory perception of temperature stimulus GO:0050951 12 6 0,000 7,22E-03 0,04980294 ! protein amino acid dealkylation GO:0008214 12 6 0,000 7,22E-03 0,04965859 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 7,22E-03 0,04951507 ! regulation of odontogenesis GO:0042481 8 6 0,000 7,22E-03 0,04937237 ! mechanosensory behavior GO:0007638 8 6 0,000 7,22E-03 0,0492305 ! ovulation from ovarian follicle GO:0001542 7 6 0,000 7,22E-03 0,04908944 ! negative regulation of endocytosis GO:0045806 8 6 0,000 7,22E-03 0,04894918 ! response to interferon-gamma GO:0034341 12 6 0,000 7,22E-03 0,04880972 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 7,22E-03 0,04867106 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 9 6 0,000 7,22E-03 0,04853318 ! negative regulation of viral genome replication GO:0045071 8 6 0,000 7,22E-03 0,04839608 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 6 6 0,000 7,22E-03 0,04825975 ! spinal cord dorsal/ventral patterning GO:0021513 8 6 0,000 7,22E-03 0,04812419 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 17 6 0,000 7,22E-03 0,04798939 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 11 6 0,000 7,22E-03 0,04785534 ! cGMP-mediated signaling GO:0019934 11 6 0,000 7,22E-03 0,04772204 ! activation of MAPKKK activity GO:0000185 11 6 0,000 7,22E-03 0,04758948 ! inositol phosphate-mediated signaling GO:0048016 10 6 0,000 7,22E-03 0,04745765 ! protein lipoylation GO:0009249 10 6 0,000 7,22E-03 0,04732656 ! pigment granule organization GO:0048753 11 6 0,000 7,22E-03 0,04719618 ! drug transport GO:0015893 6 6 0,000 7,22E-03 0,04706652 ! transepithelial chloride transport GO:0030321 10 6 0,000 7,22E-03 0,04693757 GO:0070633|transepithelial transport, ! cysteine metabolic process GO:0006534 8 6 0,000 7,22E-03 0,04680933 ! negative regulation of survival gene product expression GO:0008634 9 6 0,000 7,22E-03 0,04668178 ! regulation of defense response to virus by host GO:0050691 7 6 0,000 7,22E-03 0,04655493 ! glutamate catabolic process GO:0006538 11 6 0,000 7,22E-03 0,04642876 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 7,22E-03 0,04630328 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 7,22E-03 0,04617847 ! adenohypophysis development GO:0021984 10 6 0,000 7,22E-03 0,04605434 ! response to pH GO:0009268 10 6 0,000 7,22E-03 0,04593087 ! hyperosmotic response GO:0006972 9 6 0,000 7,22E-03 0,04580806 ! microtubule nucleation GO:0007020 10 6 0,000 7,22E-03 0,0456859 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 6 0,000 7,22E-03 0,0455644 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 6 0,000 7,22E-03 0,04544354 ! melanin biosynthetic process from tyrosine GO:0006583 9 6 0,000 7,22E-03 0,04532331 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 7,22E-03 0,04520373 ! vascular smooth muscle contraction GO:0014829 11 6 0,000 7,22E-03 0,04508477 ! regulation of retinoic acid receptor signaling pathway GO:0048385 13 6 0,000 7,22E-03 0,04496644 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 7,22E-03 0,04484873 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 7,22E-03 0,04473163 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 7,22E-03 0,04461514 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 7,22E-03 0,04449925 ! purine salvage GO:0043101 9 6 0,000 7,22E-03 0,04438397 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 7,22E-03 0,04426928 ! peptidyl-threonine phosphorylation GO:0018107 16 6 0,000 7,22E-03 0,04415519 ! nucleoside transport GO:0015858 7 6 0,000 7,22E-03 0,04404168 ! organic alcohol transport GO:0015850 9 6 0,000 7,22E-03 0,04392875 ! T cell mediated immunity GO:0002456 12 6 0,000 7,22E-03 0,0438164 ! folic acid transport GO:0015884 11 6 0,000 7,22E-03 0,04370462 ! male sex determination GO:0030238 11 6 0,000 7,22E-03 0,04359342 ! carnitine transport GO:0015879 8 6 0,000 7,22E-03 0,04348277 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 7,22E-03 0,04337269 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,22E-03 0,04326316 ! negative regulation of DNA recombination GO:0045910 10 6 0,000 7,22E-03 0,04315419 ! positive regulation of exocytosis GO:0045921 9 6 0,000 7,22E-03 0,04304576 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 7,22E-03 0,04293788 ! parturition GO:0007567 13 6 0,000 7,22E-03 0,04283053 ! determination of anterior/posterior axis, embryo GO:0008595 10 6 0,000 7,22E-03 0,04272372 GO:0007351|tripartite regional subdivision, ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 7,22E-03 0,04261745 ! lipopolysaccharide biosynthetic process GO:0009103 6 6 0,000 7,22E-03 0,04251169 ! regulation of centrosome cycle GO:0046605 8 6 0,000 7,22E-03 0,04240647 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 7,22E-03 0,04230176 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 7,22E-03 0,04219757 ! regulation of cholesterol biosynthetic process GO:0045540 8 6 0,000 7,22E-03 0,04209389 ! homeostasis of number of cells within a tissue GO:0048873 10 6 0,000 7,22E-03 0,04199072 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 7,22E-03 0,04188805 ! negative regulation of gliogenesis GO:0014014 17 6 0,000 7,22E-03 0,04178589 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 10 6 0,000 7,22E-03 0,04168422 ! neural nucleus development GO:0048857 12 6 0,000 7,22E-03 0,04158304 ! forebrain morphogenesis GO:0048853 14 6 0,000 7,22E-03 0,04148236 ! hyaluronan metabolic process GO:0030212 7 6 0,000 7,22E-03 0,04138216 ! purine base biosynthetic process GO:0009113 14 6 0,000 7,22E-03 0,04128244 ! interaction with symbiont GO:0051702 9 6 0,000 7,22E-03 0,0411832 ! regulation of dendrite development GO:0050773 13 6 0,000 7,22E-03 0,04108444 ! anterograde axon cargo transport GO:0008089 9 6 0,000 7,22E-03 0,04098616 ! positive regulation of organ growth GO:0046622 7 6 0,000 7,22E-03 0,04088834 ! eating behavior GO:0042755 6 6 0,000 7,22E-03 0,04079098 ! regulation of T cell cytokine production GO:0002724 11 6 0,000 7,22E-03 0,04069409 ! transcription-coupled nucleotide-excision repair GO:0006283 7 6 0,000 7,22E-03 0,04059766 ! response to copper ion GO:0046688 9 6 0,000 7,22E-03 0,04050169 ! negative regulation of lymphocyte mediated immunity GO:0002707 13 6 0,000 7,22E-03 0,04040616 GO:0002704|negative regulation of leukocyte mediated immunity, ! response to exogenous dsRNA GO:0043330 8 6 0,000 7,22E-03 0,04031109 ! establishment of melanosome localization GO:0032401 9 6 0,000 7,22E-03 0,04021646 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,22E-03 0,04012228 ! negative regulation of protein kinase B signaling cascade GO:0051898 12 6 0,000 7,22E-03 0,04002854 ! positive regulation of B cell differentiation GO:0045579 10 6 0,000 7,22E-03 0,03993523 ! regulation of dopamine secretion GO:0014059 14 6 0,000 7,22E-03 0,03984236 ! nucleoside catabolic process GO:0009164 7 6 0,000 7,22E-03 0,03974991 ! hair follicle maturation GO:0048820 8 6 0,000 7,22E-03 0,0396579 ! cranial nerve morphogenesis GO:0021602 7 6 0,000 7,22E-03 0,03956631 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 7,22E-03 0,03947515 ! positive regulation of interleukin-5 production GO:0032754 9 6 0,000 7,22E-03 0,0393844 GO:0032736|positive regulation of interleukin-13 production, ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 7,22E-03 0,03929407 ! rhombomere development GO:0021546 6 6 0,000 7,22E-03 0,03920415 ! positive regulation of Rho GTPase activity GO:0032321 12 6 0,000 7,22E-03 0,03911464 ! G2 phase GO:0051319 15 6 0,000 7,22E-03 0,03902554 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 10 6 0,000 7,22E-03 0,03893685 GO:0050000|chromosome localization, ! regulation of mast cell activation GO:0033003 7 6 0,000 7,22E-03 0,03884856 ! muscle cell proliferation GO:0033002 9 6 0,000 7,22E-03 0,03876066 ! membrane to membrane docking GO:0022614 12 6 0,000 7,22E-03 0,03867317 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 10 6 0,000 7,22E-03 0,03858607 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 12 6 0,000 7,22E-03 0,03849936 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 6 0,000 7,22E-03 0,03841303 ! receptor internalization GO:0031623 9 6 0,000 7,22E-03 0,0383271 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 7,22E-03 0,03824155 GO:0031272|regulation of pseudopodium assembly, ! regulation of respiratory burst GO:0060263 9 6 0,000 7,22E-03 0,03815638 ! coenzyme A metabolic process GO:0015936 9 6 0,000 7,22E-03 0,03807158 ! myeloid dendritic cell activation GO:0001773 11 6 0,000 7,22E-03 0,03798717 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 12 6 0,000 7,22E-03 0,03790313 ! peptidyl-histidine modification GO:0018202 10 6 0,000 7,22E-03 0,03781945 ! axonal fasciculation GO:0007413 10 6 0,000 7,22E-03 0,03773615 ! regulation of muscle cell apoptosis GO:0010660 9 6 0,000 7,22E-03 0,03765322 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 7,22E-03 0,03757064 GO:0015991|ATP hydrolysis coupled proton transport, ! midbrain development GO:0030901 7 6 0,000 7,22E-03 0,03748843 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 7,22E-03 0,03740658 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 7,22E-03 0,03732508 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 7 6 0,000 7,22E-03 0,03724394 ! progesterone metabolic process GO:0042448 8 6 0,000 7,22E-03 0,03716315 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 7,22E-03 0,03708271 ! glycolipid catabolic process GO:0019377 14 6 0,000 7,22E-03 0,03700262 GO:0046479|glycosphingolipid catabolic process, ! nonprotein amino acid metabolic process GO:0019794 10 6 0,000 7,22E-03 0,03692287 ! negative regulation of axon extension GO:0030517 13 6 0,000 7,22E-03 0,03684347 ! removal of superoxide radicals GO:0019430 10 6 0,000 7,22E-03 0,03676441 ! triglyceride catabolic process GO:0019433 8 6 0,000 7,22E-03 0,03668568 ! protein modification by small protein removal GO:0070646 10 6 0,000 7,22E-03 0,03660729 GO:0016579|protein deubiquitination, ! adult feeding behavior GO:0008343 6 6 0,000 7,22E-03 0,03652924 ! regulation of Rac protein signal transduction GO:0035020 9 6 0,000 7,22E-03 0,03645152 ! glial cell migration GO:0008347 11 6 0,000 7,22E-03 0,03637413 ! blastocyst growth GO:0001832 17 6 0,000 7,22E-03 0,03629706 ! pigment granule transport GO:0051904 12 6 0,000 7,22E-03 0,03622032 ! lymphocyte activation during immune response GO:0002285 10 6 0,000 7,22E-03 0,03614391 ! cerebellar cortex formation GO:0021697 9 6 0,000 7,22E-03 0,03606782 ! catecholamine transport GO:0051937 7 6 0,000 7,22E-03 0,03599204 ! hemopoietic progenitor cell differentiation GO:0002244 14 6 0,000 7,22E-03 0,03591659 ! positive regulation of actin filament bundle formation GO:0032233 16 6 0,000 7,22E-03 0,03584145 ! organ or tissue specific immune response GO:0002251 7 6 0,000 7,22E-03 0,03576662 ! positive regulation of smooth muscle contraction GO:0045987 10 6 0,000 7,22E-03 0,03569211 ! spindle assembly GO:0051225 6 6 0,000 7,22E-03 0,03561791 ! ensheathment of axons in the peripheral nervous system GO:0032292 15 6 0,000 7,22E-03 0,03554401 GO:0022011|myelination in the peripheral nervous system, ! protein prenylation GO:0018342 10 6 0,000 7,22E-03 0,03547042 ! negative regulation of synaptic transmission GO:0050805 12 6 0,000 7,22E-03 0,03539713 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 7,22E-03 0,03532415 ! NAD biosynthetic process GO:0009435 9 6 0,000 7,22E-03 0,03525147 ! positive regulation of coagulation GO:0050820 11 6 0,000 7,22E-03 0,03517908 ! cellular anion homeostasis GO:0030002 9 6 0,000 7,22E-03 0,03510699 GO:0055081|anion homeostasis, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 8,418E-03 0,04085078 ! behavioral response to cocaine GO:0048148 13 7 0,000 8,418E-03 0,04076741 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 8,418E-03 0,04068438 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 10 7 0,000 8,418E-03 0,04060169 ! chaperone mediated protein folding requiring cofactor GO:0051085 9 7 0,000 8,418E-03 0,04051934 ! prostate gland development GO:0030850 11 7 0,000 8,418E-03 0,04043731 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 8,418E-03 0,04035562 ! regulation of hormone biosynthetic process GO:0046885 12 7 0,000 8,418E-03 0,04027426 ! synaptonemal complex assembly GO:0007130 11 7 0,000 8,418E-03 0,04019323 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 10 7 0,000 8,418E-03 0,04011252 ! male meiosis GO:0007140 10 7 0,000 8,418E-03 0,04003213 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 8,418E-03 0,03995207 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! reproductive behavior GO:0019098 12 7 0,000 8,418E-03 0,03987232 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 8,418E-03 0,03979289 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 8,418E-03 0,03971378 ! oligopeptide transport GO:0006857 11 7 0,000 8,418E-03 0,03963499 ! protein amino acid sulfation GO:0006477 9 7 0,000 8,418E-03 0,0395565 GO:0051923|sulfation, ! N-terminal protein amino acid acetylation GO:0006474 9 7 0,000 8,418E-03 0,03947833 ! establishment of tissue polarity GO:0007164 10 7 0,000 8,418E-03 0,03940046 ! receptor guanylyl cyclase signaling pathway GO:0007168 7 7 0,000 8,418E-03 0,0393229 ! RNA methylation GO:0001510 11 7 0,000 8,418E-03 0,03924564 ! negative regulation of cell-cell adhesion GO:0022408 20 7 0,000 8,418E-03 0,03916869 ! positive regulation of cell-cell adhesion GO:0022409 17 7 0,000 8,418E-03 0,03909204 ! pericardium development GO:0060039 9 7 0,000 8,418E-03 0,03901569 ! macrophage chemotaxis GO:0048246 10 7 0,000 8,418E-03 0,03893964 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 8,418E-03 0,03886388 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 8,418E-03 0,03878841 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 8,418E-03 0,03871324 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 8,418E-03 0,03863836 ! cerebral cortex cell migration GO:0021795 11 7 0,000 8,418E-03 0,03856377 ! opsonization GO:0008228 9 7 0,000 8,418E-03 0,03848947 ! tachykinin receptor signaling pathway GO:0007217 12 7 0,000 8,418E-03 0,03841545 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 8,418E-03 0,03834171 ! regulation of dopamine metabolic process GO:0042053 10 7 0,000 8,418E-03 0,03826826 GO:0042069|regulation of catecholamine metabolic process, ! glucocorticoid metabolic process GO:0008211 8 7 0,000 8,418E-03 0,03819509 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 8,418E-03 0,0381222 ! chemosensory behavior GO:0007635 9 7 0,000 8,418E-03 0,03804959 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 8,418E-03 0,03797725 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 8,418E-03 0,03790519 ! leukocyte degranulation GO:0043299 11 7 0,000 8,418E-03 0,0378334 ! positive regulation of glycolysis GO:0045821 13 7 0,000 8,418E-03 0,03776188 ! DNA ligation during DNA repair GO:0051103 10 7 0,000 8,418E-03 0,03769063 ! positive regulation of heart rate GO:0010460 11 7 0,000 8,418E-03 0,03761965 ! protein-cofactor linkage GO:0018065 13 7 0,000 8,418E-03 0,03754893 ! lipopolysaccharide metabolic process GO:0008653 7 7 0,000 8,418E-03 0,03747849 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 8,418E-03 0,0374083 ! spinal cord patterning GO:0021511 9 7 0,000 8,418E-03 0,03733838 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 8,418E-03 0,03726872 ! thymic T cell selection GO:0045061 15 7 0,000 8,418E-03 0,03719932 ! regulation of transcriptional preinitiation complex assembly GO:0045898 11 7 0,000 8,418E-03 0,03713017 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 8,418E-03 0,03706129 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 8,418E-03 0,03699265 ! ovulation GO:0030728 8 7 0,000 8,418E-03 0,03692428 ! regulation of isotype switching to IgG isotypes GO:0048302 11 7 0,000 8,418E-03 0,03685615 ! histidine metabolic process GO:0006547 7 7 0,000 8,418E-03 0,03678827 GO:0009075|histidine family amino acid metabolic process, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 7 0,000 8,418E-03 0,03672065 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 8,418E-03 0,03665327 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! deoxyribonucleotide biosynthetic process GO:0009263 9 7 0,000 8,418E-03 0,03658614 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 8,418E-03 0,03651926 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! ER overload response GO:0006983 8 7 0,000 8,418E-03 0,03645261 ! thyroid hormone generation GO:0006590 11 7 0,000 8,418E-03 0,03638622 ! endosome organization GO:0007032 10 7 0,000 8,418E-03 0,03632006 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 8,418E-03 0,03625414 GO:0021940|positive regulation of granule cell precursor proliferation, ! positive regulation of interleukin-8 biosynthetic process GO:0045416 8 7 0,000 8,418E-03 0,03618847 ! phasic smooth muscle contraction GO:0014821 13 7 0,000 8,418E-03 0,03612303 ! urea metabolic process GO:0019627 9 7 0,000 8,418E-03 0,03605782 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 14 7 0,000 8,418E-03 0,03599285 ! vesicle fusion GO:0006906 15 7 0,000 8,418E-03 0,03592812 ! positive regulation of insulin secretion GO:0032024 9 7 0,000 8,418E-03 0,03586361 ! maintenance of protein location in nucleus GO:0051457 17 7 0,000 8,418E-03 0,03579934 ! intracellular pH reduction GO:0051452 11 7 0,000 8,418E-03 0,0357353 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 10 7 0,000 8,418E-03 0,03567149 GO:0046464|acylglycerol catabolic process, ! asymmetric protein localization GO:0008105 10 7 0,000 8,418E-03 0,0356079 ! organ growth GO:0035265 13 7 0,000 8,418E-03 0,03554454 ! positive regulation of mesenchymal cell proliferation GO:0002053 10 7 0,000 8,418E-03 0,03548141 ! Rac protein signal transduction GO:0016601 7 7 0,000 8,418E-03 0,0354185 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 7 0,000 8,418E-03 0,03535581 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 8 7 0,000 8,418E-03 0,03529334 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! retinol metabolic process GO:0042572 9 7 0,000 8,418E-03 0,0352311 ! positive regulation of mitotic cell cycle GO:0045931 13 7 0,000 8,418E-03 0,03516907 ! rRNA modification GO:0000154 12 7 0,000 8,418E-03 0,03510726 ! negative regulation of translational initiation GO:0045947 9 7 0,000 8,418E-03 0,03504567 ! DNA damage response, signal transduction resulting in transcription GO:0042772 14 7 0,000 8,418E-03 0,0349843 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 20 7 0,000 8,418E-03 0,03492313 ! protein heterooligomerization GO:0051291 10 7 0,000 8,418E-03 0,03486219 ! response to UV-B GO:0010224 11 7 0,000 8,418E-03 0,03480145 ! astrocyte development GO:0014002 15 7 0,000 8,418E-03 0,03474093 ! intermediate filament organization GO:0045109 12 7 0,000 8,418E-03 0,03468061 ! cardiac muscle cell development GO:0055013 9 7 0,000 8,418E-03 0,03462051 ! fibrinolysis GO:0042730 9 7 0,000 8,418E-03 0,03456061 ! peptidyl-arginine modification GO:0018195 9 7 0,000 8,418E-03 0,03450092 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 7 0,000 8,418E-03 0,03444144 ! blastoderm segmentation GO:0007350 11 7 0,000 8,418E-03 0,03438216 ! skeletal muscle contraction GO:0003009 8 7 0,000 8,418E-03 0,03432308 ! B cell lineage commitment GO:0002326 17 7 0,000 8,418E-03 0,03426421 ! DNA topological change GO:0006265 10 7 0,000 8,418E-03 0,03420554 ! regulation of fat cell differentiation GO:0045598 10 7 0,000 8,418E-03 0,03414706 ! melanosome localization GO:0032400 10 7 0,000 8,418E-03 0,03408879 ! enucleate erythrocyte differentiation GO:0043353 10 7 0,000 8,418E-03 0,03403072 ! regulation of interleukin-5 production GO:0032674 10 7 0,000 8,418E-03 0,03397285 ! glycosylceramide metabolic process GO:0006677 10 7 0,000 8,418E-03 0,03391517 ! mast cell activation GO:0045576 10 7 0,000 8,418E-03 0,03385768 ! multicellular organismal aging GO:0010259 11 7 0,000 8,418E-03 0,03380039 ! negative regulation of focal adhesion formation GO:0051895 16 7 0,000 8,418E-03 0,0337433 ! gas homeostasis GO:0033483 12 7 0,000 8,418E-03 0,0336864 ! negative regulation of T cell differentiation GO:0045581 9 7 0,000 8,418E-03 0,03362968 ! phosphatidylinositol biosynthetic process GO:0006661 11 7 0,000 8,418E-03 0,03357316 ! Schwann cell development GO:0014044 16 7 0,000 8,418E-03 0,03351683 ! dendrite morphogenesis GO:0048813 12 7 0,000 8,418E-03 0,03346069 ! regulation of interleukin-13 production GO:0032656 12 7 0,000 8,418E-03 0,03340474 ! positive regulation of interleukin-4 production GO:0032753 10 7 0,000 8,418E-03 0,03334897 ! molybdopterin cofactor biosynthetic process GO:0032324 10 7 0,000 8,418E-03 0,03329339 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 11 7 0,000 8,418E-03 0,03323799 ! neural tube patterning GO:0021532 8 7 0,000 8,418E-03 0,03318278 ! histone ubiquitination GO:0016574 10 7 0,000 8,418E-03 0,03312775 ! regulation of meiosis GO:0040020 12 7 0,000 8,418E-03 0,0330729 GO:0051445|regulation of meiotic cell cycle, ! eye photoreceptor cell differentiation GO:0001754 14 7 0,000 8,418E-03 0,03301824 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 12 7 0,000 8,418E-03 0,03296375 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 8,418E-03 0,03290944 GO:0002714|positive regulation of B cell mediated immunity, ! mitochondrion morphogenesis GO:0070584 12 7 0,000 8,418E-03 0,03285532 ! regulation of lipid transport GO:0032368 13 7 0,000 8,418E-03 0,03280137 ! regulation of cell division GO:0051302 9 7 0,000 8,418E-03 0,03274759 ! regulation of inflammatory response to antigenic stimulus GO:0002861 14 7 0,000 8,418E-03 0,032694 ! neutrophil homeostasis GO:0001780 8 7 0,000 8,418E-03 0,03264058 ! regulation of macrophage activation GO:0043030 12 7 0,000 8,418E-03 0,03258733 ! negative regulation of nuclear division GO:0051784 18 7 0,000 8,418E-03 0,03253426 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 8,418E-03 0,03248135 ! diuresis GO:0030146 11 7 0,000 8,418E-03 0,03242862 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 9 7 0,000 8,418E-03 0,03237607 ! positive regulation of epidermis development GO:0045684 11 7 0,000 8,418E-03 0,03232368 ! thiamin metabolic process GO:0006772 8 7 0,000 8,418E-03 0,03227146 ! positive regulation of leukocyte chemotaxis GO:0002690 15 7 0,000 8,418E-03 0,03221941 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of epidermal cell differentiation GO:0045604 10 7 0,000 8,418E-03 0,03216752 ! negative regulation of transmission of nerve impulse GO:0051970 13 7 0,000 8,418E-03 0,03211581 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 8,418E-03 0,03206426 ! dopamine biosynthetic process GO:0042416 15 7 0,000 8,418E-03 0,03201287 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 8,418E-03 0,03196165 ! lymph node development GO:0048535 9 7 0,000 8,418E-03 0,0319106 ! anterior/posterior axis specification GO:0009948 11 7 0,000 8,418E-03 0,0318597 ! negative regulation of viral reproduction GO:0048525 9 7 0,000 8,418E-03 0,03180897 ! regulation of T cell mediated cytotoxicity GO:0001914 15 7 0,000 8,418E-03 0,0317584 ! positive regulation of glucose import GO:0046326 7 7 0,000 8,418E-03 0,03170799 GO:0010828|positive regulation of glucose transport, ! endosome to lysosome transport GO:0008333 11 7 0,000 8,418E-03 0,03165774 ! ATP catabolic process GO:0006200 10 7 0,000 8,418E-03 0,03160765 ! establishment of pigment granule localization GO:0051905 13 7 0,000 8,418E-03 0,03155771 ! positive regulation of fibrinolysis GO:0051919 8 7 0,000 8,418E-03 0,03150794 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 8,418E-03 0,03145832 ! negative regulation of calcium ion transport GO:0051926 8 7 0,000 8,418E-03 0,03140886 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 8,418E-03 0,03135955 ! positive regulation of blood vessel endothelial cell migration GO:0043536 17 7 0,000 8,418E-03 0,0313104 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 8,418E-03 0,0312614 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 8,418E-03 0,03121255 ! muscle adaptation GO:0043500 12 7 0,000 8,418E-03 0,03116386 ! amino sugar catabolic process GO:0046348 9 7 0,000 8,418E-03 0,03111532 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 8 7 0,000 8,418E-03 0,03106693 ! retina homeostasis GO:0001895 9 7 0,000 8,418E-03 0,03101868 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 8,418E-03 0,03097059 ! regulation of growth hormone secretion GO:0060123 14 7 0,000 8,418E-03 0,03092265 ! regulation of T cell receptor signaling pathway GO:0050856 12 7 0,000 8,418E-03 0,03087486 ! positive regulation of microtubule polymerization GO:0031116 12 7 0,000 8,418E-03 0,03082721 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 8,418E-03 0,03077971 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 8 0,000 9,615E-03 0,0351024 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 16 8 0,000 9,615E-03 0,03504848 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 9,615E-03 0,03499473 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 9,615E-03 0,03494114 ! oligosaccharide biosynthetic process GO:0009312 14 8 0,000 9,615E-03 0,03488771 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 8 0,000 9,615E-03 0,03483445 ! negative regulation of cellular catabolic process GO:0031330 10 8 0,000 9,615E-03 0,03478135 ! positive regulation of small GTPase mediated signal transduction GO:0051057 16 8 0,000 9,615E-03 0,03472841 GO:0046579|positive regulation of Ras protein signal transduction, ! generation of neurons in the forebrain GO:0021872 11 8 0,000 9,615E-03 0,03467563 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 9,615E-03 0,03462301 ! cell proliferation in forebrain GO:0021846 10 8 0,000 9,615E-03 0,03457055 ! neutral lipid catabolic process GO:0046461 11 8 0,000 9,615E-03 0,03451825 ! N-glycan processing GO:0006491 12 8 0,000 9,615E-03 0,03446611 ! Golgi to endosome transport GO:0006895 16 8 0,000 9,615E-03 0,03441412 ! glycosaminoglycan catabolic process GO:0006027 11 8 0,000 9,615E-03 0,03436229 ! negative regulation of JAK-STAT cascade GO:0046426 18 8 0,000 9,615E-03 0,03431062 ! mRNA stabilization GO:0048255 16 8 0,000 9,615E-03 0,0342591 GO:0043489|RNA stabilization, ! induction of positive chemotaxis GO:0050930 16 8 0,000 9,615E-03 0,03420774 ! neurotransmitter uptake GO:0001504 10 8 0,000 9,615E-03 0,03415653 ! lipoprotein transport GO:0042953 14 8 0,000 9,615E-03 0,03410548 ! membrane hyperpolarization GO:0060081 11 8 0,000 9,615E-03 0,03405457 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 9,615E-03 0,03400382 ! keratinocyte proliferation GO:0043616 15 8 0,000 9,615E-03 0,03395322 ! middle ear morphogenesis GO:0042474 9 8 0,000 9,615E-03 0,03390277 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 9,615E-03 0,03385247 ! amyloid precursor protein catabolic process GO:0042987 13 8 0,000 9,615E-03 0,03380232 ! bile acid and bile salt transport GO:0015721 12 8 0,000 9,615E-03 0,03375231 ! ganglioside metabolic process GO:0001573 16 8 0,000 9,615E-03 0,03370246 ! regulation of mesenchymal cell proliferation GO:0010464 12 8 0,000 9,615E-03 0,03365275 ! reflex GO:0060004 16 8 0,000 9,615E-03 0,03360319 ! positive regulation of isotype switching GO:0045830 16 8 0,000 9,615E-03 0,03355377 GO:0045911|positive regulation of DNA recombination, ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 9,615E-03 0,0335045 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of interleukin-12 biosynthetic process GO:0045075 10 8 0,000 9,615E-03 0,03345537 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 9,615E-03 0,03340639 ! glycerolipid catabolic process GO:0046503 11 8 0,000 9,615E-03 0,03335755 ! positive regulation of chemokine biosynthetic process GO:0045080 9 8 0,000 9,615E-03 0,03330885 ! hemoglobin metabolic process GO:0020027 12 8 0,000 9,615E-03 0,0332603 ! ceramide biosynthetic process GO:0046513 9 8 0,000 9,615E-03 0,03321188 ! nerve growth factor receptor signaling pathway GO:0048011 12 8 0,000 9,615E-03 0,03316361 ! insulin-like growth factor receptor signaling pathway GO:0048009 16 8 0,000 9,615E-03 0,03311548 ! adrenal gland development GO:0030325 18 8 0,000 9,615E-03 0,03306748 ! embryonic cranial skeleton morphogenesis GO:0048701 12 8 0,000 9,615E-03 0,03301963 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 9,615E-03 0,03297191 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 9,615E-03 0,03292433 ! proline metabolic process GO:0006560 9 8 0,000 9,615E-03 0,03287689 ! polyamine biosynthetic process GO:0006596 9 8 0,000 9,615E-03 0,03282959 ! regulation of interleukin-8 biosynthetic process GO:0045414 10 8 0,000 9,615E-03 0,03278242 ! regulation of pigmentation during development GO:0048070 18 8 0,000 9,615E-03 0,03273538 ! central nervous system neuron axonogenesis GO:0021955 16 8 0,000 9,615E-03 0,03268849 GO:0021952|central nervous system projection neuron axonogenesis, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 15 8 0,000 9,615E-03 0,03264172 ! regulation of type I interferon production GO:0032479 8 8 0,000 9,615E-03 0,03259509 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 9,615E-03 0,03254859 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of activated T cell proliferation GO:0042104 19 8 0,000 9,615E-03 0,03250223 ! galactose metabolic process GO:0006012 14 8 0,000 9,615E-03 0,03245599 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 9,615E-03 0,03240989 ! regulation of vascular permeability GO:0043114 12 8 0,000 9,615E-03 0,03236392 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 9,615E-03 0,03231808 ! neurotransmitter catabolic process GO:0042135 16 8 0,000 9,615E-03 0,03227237 ! ruffle organization GO:0031529 12 8 0,000 9,615E-03 0,03222678 ! osteoblast development GO:0002076 14 8 0,000 9,615E-03 0,03218133 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 9,615E-03 0,032136 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 9,615E-03 0,03209081 ! regulation of Notch signaling pathway GO:0008593 22 8 0,000 9,615E-03 0,03204573 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 9,615E-03 0,03200079 GO:0030204|chondroitin sulfate metabolic process, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 14 8 0,000 9,615E-03 0,03195597 ! G1 DNA damage checkpoint GO:0031571 19 8 0,000 9,615E-03 0,03191128 ! protein retention in ER lumen GO:0006621 16 8 0,000 9,615E-03 0,03186671 ! cardiac muscle cell differentiation GO:0055007 12 8 0,000 9,615E-03 0,03182226 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 8 0,000 9,615E-03 0,03177794 ! regulation of circadian rhythm GO:0042752 13 8 0,000 9,615E-03 0,03173375 ! pigment granule localization GO:0051875 14 8 0,000 9,615E-03 0,03168967 ! positive regulation of cytokine production during immune response GO:0002720 12 8 0,000 9,615E-03 0,03164572 ! antigen processing and presentation of endogenous antigen GO:0019883 14 8 0,000 9,615E-03 0,03160189 ! response to tropane GO:0014073 14 8 0,000 9,615E-03 0,03155818 GO:0042220|response to cocaine, ! positive regulation of systemic arterial blood pressure GO:0003084 12 8 0,000 9,615E-03 0,03151459 ! embryonic axis specification GO:0000578 12 8 0,000 9,615E-03 0,03147112 ! negative regulation of interferon-gamma production GO:0032689 12 8 0,000 9,615E-03 0,03142777 ! negative regulation of systemic arterial blood pressure GO:0003085 18 8 0,000 9,615E-03 0,03138454 ! sphingomyelin metabolic process GO:0006684 11 8 0,000 9,615E-03 0,03134143 ! snRNA metabolic process GO:0016073 10 8 0,000 9,615E-03 0,03129844 GO:0016180|snRNA processing, ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 9,615E-03 0,03125557 ! regulation of focal adhesion formation GO:0051893 17 8 0,000 9,615E-03 0,03121281 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 9,615E-03 0,03117017 ! regulation of mitochondrial membrane potential GO:0051881 14 8 0,000 9,615E-03 0,03112764 ! regulation of interleukin-10 production GO:0032653 12 8 0,000 9,615E-03 0,03108524 ! positive regulation of monooxygenase activity GO:0032770 12 8 0,000 9,615E-03 0,03104294 ! protein import into peroxisome matrix GO:0016558 15 8 0,000 9,615E-03 0,03100076 ! establishment of nucleus localization GO:0040023 14 8 0,000 9,615E-03 0,0309587 ! icosanoid secretion GO:0032309 12 8 0,000 9,615E-03 0,03091675 GO:0050482|arachidonic acid secretion, ! intracellular lipid transport GO:0032365 14 8 0,000 9,615E-03 0,03087492 ! regulation of transcription from RNA polymerase III promoter GO:0006359 11 8 0,000 9,615E-03 0,03083319 ! negative regulation of oxidoreductase activity GO:0051354 13 8 0,000 9,615E-03 0,03079158 ! positive regulation of interleukin-1 beta secretion GO:0050718 10 8 0,000 9,615E-03 0,03075008 ! regulation of T-helper 1 type immune response GO:0002825 10 8 0,000 9,615E-03 0,0307087 ! S phase GO:0051320 8 8 0,000 9,615E-03 0,03066742 GO:0000084|S phase of mitotic cell cycle, ! negative regulation of neuroblast proliferation GO:0007406 25 8 0,000 9,615E-03 0,03062626 ! regulation of macrophage differentiation GO:0045649 15 8 0,000 9,615E-03 0,0305852 ! negative regulation of osteoclast differentiation GO:0045671 12 8 0,000 9,615E-03 0,03054426 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 9,615E-03 0,03050343 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 8 0,000 9,615E-03 0,0304627 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 9,615E-03 0,03042208 ! melanin biosynthetic process GO:0042438 11 8 0,000 9,615E-03 0,03038157 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 9,615E-03 0,03034117 ! regulation of synaptogenesis GO:0051963 12 8 0,000 9,615E-03 0,03030088 ! hormone catabolic process GO:0042447 13 8 0,000 9,615E-03 0,03026069 ! nicotinamide nucleotide biosynthetic process GO:0019359 12 8 0,000 9,615E-03 0,03022061 ! quaternary ammonium group transport GO:0015697 10 8 0,000 9,615E-03 0,03018064 ! positive regulation of ATPase activity GO:0032781 16 8 0,000 9,615E-03 0,03014077 ! trophectodermal cell differentiation GO:0001829 10 8 0,000 9,615E-03 0,03010101 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 9,615E-03 0,03006135 ! regulation of telomere maintenance GO:0032204 10 8 0,000 9,615E-03 0,03002179 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 9,615E-03 0,02998234 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 9,615E-03 0,029943 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 9,615E-03 0,02990375 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 9,615E-03 0,02986461 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 9,615E-03 0,02982557 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 8 0,000 9,615E-03 0,02978664 ! negative regulation of B cell activation GO:0050869 17 8 0,000 9,615E-03 0,0297478 ! behavioral response to nicotine GO:0035095 13 8 0,000 9,615E-03 0,02970907 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 9,615E-03 0,02967043 GO:0000076|DNA replication checkpoint, ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 9,615E-03 0,0296319 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 16 8 0,000 9,615E-03 0,02959347 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 14 8 0,000 9,615E-03 0,02955513 ! regulation of microtubule polymerization GO:0031113 14 8 0,000 9,615E-03 0,0295169 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01081071 0,03314445 ! regulation of developmental growth GO:0048638 14 9 0,000 0,01081071 0,03310169 ! negative regulation of smooth muscle cell proliferation GO:0048662 15 9 0,000 0,01081071 0,03305903 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01081071 0,03301648 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 9 0,000 0,01081071 0,03297404 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 11 9 0,000 0,01081071 0,03293172 ! negative regulation of lipid biosynthetic process GO:0051055 13 9 0,000 0,01081071 0,0328895 ! glycerol-3-phosphate metabolic process GO:0006072 11 9 0,000 0,01081071 0,03284738 ! regulation of cellular amine metabolic process GO:0033238 12 9 0,000 0,01081071 0,03280538 ! cell volume homeostasis GO:0006884 14 9 0,000 0,01081071 0,03276348 ! regulation of epidermal growth factor receptor activity GO:0007176 14 9 0,000 0,01081071 0,03272169 GO:0010469|regulation of receptor activity, ! regulation of smooth muscle cell migration GO:0014910 22 9 0,000 0,01081071 0,03268001 ! UTP metabolic process GO:0046051 10 9 0,000 0,01081071 0,03263843 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! prostaglandin biosynthetic process GO:0001516 15 9 0,000 0,01081071 0,03259696 GO:0046457|prostanoid biosynthetic process, ! succinate metabolic process GO:0006105 16 9 0,000 0,01081071 0,03255559 ! smoothened signaling pathway GO:0007224 10 9 0,000 0,01081071 0,03251433 ! protein complex disassembly GO:0043241 17 9 0,000 0,01081071 0,03247317 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01081071 0,03243212 ! estrogen metabolic process GO:0008210 16 9 0,000 0,01081071 0,03239117 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01081071 0,03235032 ! photoreceptor cell development GO:0042461 17 9 0,000 0,01081071 0,03230958 GO:0046530|photoreceptor cell differentiation, ! negative regulation of muscle cell differentiation GO:0051148 10 9 0,000 0,01081071 0,03226894 ! microtubule bundle formation GO:0001578 14 9 0,000 0,01081071 0,0322284 ! T-helper 1 type immune response GO:0042088 13 9 0,000 0,01081071 0,03218796 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 22 9 0,000 0,01081071 0,03214763 ! lung alveolus development GO:0048286 18 9 0,000 0,01081071 0,03210739 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01081071 0,03206726 ! pseudouridine synthesis GO:0001522 10 9 0,000 0,01081071 0,03202722 ! endothelial cell differentiation GO:0045446 17 9 0,000 0,01081071 0,03198729 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01081071 0,03194746 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01081071 0,03190772 ! endoderm development GO:0007492 12 9 0,000 0,01081071 0,03186808 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01081071 0,03182854 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01081071 0,0317891 ! myeloid leukocyte mediated immunity GO:0002444 12 9 0,000 0,01081071 0,03174976 ! astrocyte differentiation GO:0048708 17 9 0,000 0,01081071 0,03171051 ! L-phenylalanine metabolic process GO:0006558 11 9 0,000 0,01081071 0,03167137 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 10 9 0,000 0,01081071 0,03163231 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01081071 0,03159336 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 13 9 0,000 0,01081071 0,0315545 ! reverse cholesterol transport GO:0043691 17 9 0,000 0,01081071 0,03151573 ! indolalkylamine metabolic process GO:0006586 15 9 0,000 0,01081071 0,03147706 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! melanin metabolic process GO:0006582 15 9 0,000 0,01081071 0,03143849 ! embryonic eye morphogenesis GO:0048048 15 9 0,000 0,01081071 0,03140001 ! macrophage activation GO:0042116 14 9 0,000 0,01081071 0,03136162 ! multicellular organism growth GO:0035264 16 9 0,000 0,01081071 0,03132333 ! retrograde transport, endosome to Golgi GO:0042147 14 9 0,000 0,01081071 0,03128513 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 0,01081071 0,03124702 ! neuron apoptosis GO:0051402 12 9 0,000 0,01081071 0,03120901 ! lens development in camera-type eye GO:0002088 11 9 0,000 0,01081071 0,03117109 ! positive regulation of vasodilation GO:0045909 14 9 0,000 0,01081071 0,03113326 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01081071 0,03109552 ! positive regulation of muscle contraction GO:0045933 13 9 0,000 0,01081071 0,03105788 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01081071 0,03102032 ! regulation of smoothened signaling pathway GO:0008589 15 9 0,000 0,01081071 0,03098286 ! Schwann cell differentiation GO:0014037 20 9 0,000 0,01081071 0,03094548 ! acyl-CoA metabolic process GO:0006637 14 9 0,000 0,01081071 0,0309082 ! regulation of gliogenesis GO:0014013 21 9 0,000 0,01081071 0,03087101 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 21 9 0,000 0,01081071 0,0308339 ! oligodendrocyte development GO:0014003 13 9 0,000 0,01081071 0,03079689 ! alpha-beta T cell differentiation GO:0046632 15 9 0,000 0,01081071 0,03075996 ! segment specification GO:0007379 11 9 0,000 0,01081071 0,03072312 ! cellular extravasation GO:0045123 12 9 0,000 0,01081071 0,03068637 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01081071 0,03064971 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 13 9 0,000 0,01081071 0,03061313 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01081071 0,03057665 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01081071 0,03054025 ! antigen processing and presentation of exogenous antigen GO:0019884 11 9 0,000 0,01081071 0,03050393 ! positive regulation of production of molecular mediator of immune response GO:0002702 13 9 0,000 0,01081071 0,0304677 ! purine nucleoside triphosphate catabolic process GO:0009146 13 9 0,000 0,01081071 0,03043156 ! regulation of T cell differentiation in the thymus GO:0033081 14 9 0,000 0,01081071 0,03039551 ! response to amine stimulus GO:0014075 13 9 0,000 0,01081071 0,03035953 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of protein kinase B signaling cascade GO:0051896 16 9 0,000 0,01081071 0,03032365 ! erythrocyte development GO:0048821 13 9 0,000 0,01081071 0,03028785 ! renal water homeostasis GO:0003091 13 9 0,000 0,01081071 0,03025213 ! positive regulation of tumor necrosis factor production GO:0032760 10 9 0,000 0,01081071 0,0302165 ! nucleosome disassembly GO:0006337 13 9 0,000 0,01081071 0,03018095 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! spinal cord motor neuron differentiation GO:0021522 12 9 0,000 0,01081071 0,03014548 ! transcription from RNA polymerase I promoter GO:0006360 14 9 0,000 0,01081071 0,0301101 ! induction of an organ GO:0001759 13 9 0,000 0,01081071 0,0300748 ! leukocyte activation during immune response GO:0002366 15 9 0,000 0,01081071 0,03003959 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 11 9 0,000 0,01081071 0,03000445 ! cerebellum morphogenesis GO:0021587 13 9 0,000 0,01081071 0,0299694 GO:0021696|cerebellar cortex morphogenesis, ! retinal ganglion cell axon guidance GO:0031290 11 9 0,000 0,01081071 0,02993443 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01081071 0,02989954 ! sterol catabolic process GO:0016127 11 9 0,000 0,01081071 0,02986473 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 18 9 0,000 0,01081071 0,02983001 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01081071 0,02979536 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 14 9 0,000 0,01081071 0,0297608 ! positive regulation of interleukin-1 secretion GO:0050716 11 9 0,000 0,01081071 0,02972631 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 0,01081071 0,02969191 ! negative regulation of cytokine secretion GO:0050710 13 9 0,000 0,01081071 0,02965758 ! prophase GO:0051324 12 9 0,000 0,01081071 0,02962333 ! neuroblast proliferation GO:0007405 19 9 0,000 0,01081071 0,02958917 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 16 9 0,000 0,01081071 0,02955508 ! peptidyl-threonine modification GO:0018210 22 9 0,000 0,01081071 0,02952107 ! regulation of interleukin-1 beta secretion GO:0050706 12 9 0,000 0,01081071 0,02948713 ! ubiquinone metabolic process GO:0006743 11 9 0,000 0,01081071 0,02945328 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of erythrocyte differentiation GO:0045648 20 9 0,000 0,01081071 0,0294195 ! acid secretion GO:0046717 14 9 0,000 0,01081071 0,0293858 ! purine base metabolic process GO:0006144 18 9 0,000 0,01081071 0,02935218 ! detection of calcium ion GO:0005513 13 9 0,000 0,01081071 0,02931864 ! myeloid cell homeostasis GO:0002262 10 9 0,000 0,01081071 0,02928517 ! regulation of fibrinolysis GO:0051917 14 9 0,000 0,01081071 0,02925177 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01081071 0,02921846 ! natural killer cell mediated immunity GO:0002228 14 9 0,000 0,01081071 0,02918522 GO:0042267|natural killer cell mediated cytotoxicity, ! negative regulation of blood vessel endothelial cell migration GO:0043537 18 9 0,000 0,01081071 0,02915205 ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01081071 0,02911896 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01081071 0,02908595 ! defense response to Gram-positive bacterium GO:0050830 11 9 0,000 0,01081071 0,02905301 ! prepulse inhibition GO:0060134 14 9 0,000 0,01081071 0,02902014 ! sequestering of metal ion GO:0051238 12 9 0,000 0,01081071 0,02898735 ! lamellipodium assembly GO:0030032 12 9 0,000 0,01081071 0,02895463 ! regulation of embryonic development GO:0045995 17 9 0,000 0,01081071 0,02892199 ! mitochondrion localization GO:0051646 15 9 0,000 0,01081071 0,02888942 ! localization within membrane GO:0051668 15 9 0,000 0,01081071 0,02885693 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01200496 0,03200873 ! axon extension GO:0048675 13 10 0,000 0,01200496 0,0319728 ! neuron fate specification GO:0048665 12 10 0,000 0,01200496 0,03193696 ! regulation of epithelial cell differentiation GO:0030856 20 10 0,000 0,01200496 0,0319012 ! cortical actin cytoskeleton organization GO:0030866 24 10 0,000 0,01200496 0,03186551 ! associative learning GO:0008306 19 10 0,000 0,01200496 0,03182991 ! positive regulation of B cell proliferation GO:0030890 14 10 0,000 0,01200496 0,03179438 ! cellular copper ion homeostasis GO:0006878 14 10 0,000 0,01200496 0,03175894 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01200496 0,03172357 ! CTP metabolic process GO:0046036 11 10 0,000 0,01200496 0,03168828 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 17 10 0,000 0,01200496 0,03165307 ! GTP metabolic process GO:0046039 11 10 0,000 0,01200496 0,03161794 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01200496 0,03158289 GO:0007520|myoblast fusion, ! actin-myosin filament sliding GO:0033275 14 10 0,000 0,01200496 0,03154792 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01200496 0,03151302 ! social behavior GO:0035176 15 10 0,000 0,01200496 0,0314782 ! sulfate transport GO:0008272 12 10 0,000 0,01200496 0,03144345 ! regulation of activated T cell proliferation GO:0046006 22 10 0,000 0,01200496 0,03140878 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 19 10 0,000 0,01200496 0,03137419 ! artery development GO:0060840 20 10 0,000 0,01200496 0,03133968 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 13 10 0,000 0,01200496 0,03130524 ! response to pain GO:0048265 20 10 0,000 0,01200496 0,03127088 ! COPI coating of Golgi vesicle GO:0048205 15 10 0,000 0,01200496 0,03123659 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,01200496 0,03120237 ! phospholipid efflux GO:0033700 17 10 0,000 0,01200496 0,03116824 ! hippocampus development GO:0021766 19 10 0,000 0,01200496 0,03113417 ! positive regulation of transcription factor import into nucleus GO:0042993 21 10 0,000 0,01200496 0,03110018 ! amyloid precursor protein metabolic process GO:0042982 16 10 0,000 0,01200496 0,03106627 ! blood vessel remodeling GO:0001974 23 10 0,000 0,01200496 0,03103243 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01200496 0,03099866 ! pathogenesis GO:0009405 13 10 0,000 0,01200496 0,03096496 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01200496 0,03093134 ! two-component signal transduction system (phosphorelay) GO:0000160 15 10 0,000 0,01200496 0,0308978 ! negative regulation of striated muscle development GO:0045843 13 10 0,000 0,01200496 0,03086432 ! protein targeting to ER GO:0045047 21 10 0,000 0,01200496 0,03083092 ! regulation of S phase of mitotic cell cycle GO:0007090 19 10 0,000 0,01200496 0,03079759 ! arginine catabolic process GO:0006527 12 10 0,000 0,01200496 0,03076433 ! melanocyte differentiation GO:0030318 16 10 0,000 0,01200496 0,03073114 GO:0050931|pigment cell differentiation, ! telomere maintenance via telomerase GO:0007004 14 10 0,000 0,01200496 0,03069803 GO:0010833|telomere maintenance via telomere lengthening, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01200496 0,03066498 ! regulation of phosphoprotein phosphatase activity GO:0043666 20 10 0,000 0,01200496 0,03063201 ! regulation of stress fiber formation GO:0051492 24 10 0,000 0,01200496 0,03059911 ! positive regulation of endothelial cell migration GO:0010595 20 10 0,000 0,01200496 0,03056627 ! B cell proliferation GO:0042100 16 10 0,000 0,01200496 0,03053351 ! nucleobase biosynthetic process GO:0046112 20 10 0,000 0,01200496 0,03050082 ! mannose metabolic process GO:0006013 11 10 0,000 0,01200496 0,0304682 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01200496 0,03043565 ! forebrain cell migration GO:0021885 17 10 0,000 0,01200496 0,03040317 ! lipid digestion GO:0044241 15 10 0,000 0,01200496 0,03037075 ! substrate-bound cell migration GO:0006929 11 10 0,000 0,01200496 0,03033841 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01200496 0,03030614 ! receptor clustering GO:0043113 18 10 0,000 0,01200496 0,03027393 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01200496 0,03024179 ! UV protection GO:0009650 14 10 0,000 0,01200496 0,03020972 ! entry into host cell GO:0030260 21 10 0,000 0,01200496 0,03017772 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of lipoprotein lipase activity GO:0051004 20 10 0,000 0,01200496 0,03014579 ! behavioral fear response GO:0001662 19 10 0,000 0,01200496 0,03011392 GO:0002209|behavioral defense response, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01200496 0,03008212 ! negative regulation of ossification GO:0030279 21 10 0,000 0,01200496 0,03005039 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 23 10 0,000 0,01200496 0,03001872 ! protein homotetramerization GO:0051289 20 10 0,000 0,01200496 0,02998712 ! positive regulation of peptide secretion GO:0002793 16 10 0,000 0,01200496 0,02995559 ! response to dsRNA GO:0043331 19 10 0,000 0,01200496 0,02992413 ! DNA ligation GO:0006266 16 10 0,000 0,01200496 0,02989273 ! phosphoinositide 3-kinase cascade GO:0014065 26 10 0,000 0,01200496 0,02986139 ! regulation of interleukin-4 production GO:0032673 18 10 0,000 0,01200496 0,02983012 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01200496 0,02979892 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01200496 0,02976778 ! positive regulation of Ras GTPase activity GO:0032320 24 10 0,000 0,01200496 0,02973671 ! postreplication repair GO:0006301 16 10 0,000 0,01200496 0,0297057 ! fucose catabolic process GO:0019317 17 10 0,000 0,01200496 0,02967476 GO:0042355|L-fucose catabolic process, ! mRNA cleavage GO:0006379 14 10 0,000 0,01200496 0,02964388 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01200496 0,02961306 ! hindbrain morphogenesis GO:0021575 16 10 0,000 0,01200496 0,02958231 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 10 0,000 0,01200496 0,02955163 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 13 10 0,000 0,01200496 0,029521 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01200496 0,02949044 ! positive regulation of neuron differentiation GO:0045666 13 10 0,000 0,01200496 0,02945995 ! positive regulation of leukocyte migration GO:0002687 24 10 0,000 0,01200496 0,02942951 ! multicellular organismal water homeostasis GO:0050891 14 10 0,000 0,01200496 0,02939914 ! negative regulation of lymphocyte differentiation GO:0045620 13 10 0,000 0,01200496 0,02936883 ! methionine biosynthetic process GO:0009086 13 10 0,000 0,01200496 0,02933859 ! oocyte differentiation GO:0009994 14 10 0,000 0,01200496 0,0293084 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 14 10 0,000 0,01200496 0,02927828 ! spleen development GO:0048536 17 10 0,000 0,01200496 0,02924822 ! negative regulation of BMP signaling pathway GO:0030514 15 10 0,000 0,01200496 0,02921822 ! regulation of RNA splicing GO:0043484 15 10 0,000 0,01200496 0,02918829 ! positive regulation of viral reproduction GO:0048524 14 10 0,000 0,01200496 0,02915841 ! blastocyst formation GO:0001825 14 10 0,000 0,01200496 0,0291286 ! embryonic gut development GO:0048566 13 10 0,000 0,01200496 0,02909884 ! quinone cofactor metabolic process GO:0042375 12 10 0,000 0,01200496 0,02906915 ! cerebellar cortex development GO:0021695 14 10 0,000 0,01200496 0,02903952 ! activation of innate immune response GO:0002218 10 10 0,000 0,01200496 0,02900995 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01200496 0,02898043 ! insulin secretion GO:0030073 18 10 0,000 0,01200496 0,02895098 ! response to nicotine GO:0035094 18 10 0,000 0,01200496 0,02892159 ! establishment of cell polarity GO:0030010 12 10 0,000 0,01200496 0,02889226 ! nucleus localization GO:0051647 16 10 0,000 0,01200496 0,02886299 ! regulation of synapse organization GO:0050807 14 10 0,000 0,01200496 0,02883377 ! negative regulation of muscle development GO:0048635 14 11 0,000 0,01319783 0,03166678 ! positive regulation of glucose metabolic process GO:0010907 17 11 0,000 0,01319783 0,0316348 ! ER-associated protein catabolic process GO:0030433 17 11 0,000 0,01319783 0,03160287 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of blood pressure GO:0045776 25 11 0,000 0,01319783 0,03157102 ! cortical cytoskeleton organization GO:0030865 25 11 0,000 0,01319783 0,03153922 ! virus-host interaction GO:0019048 20 11 0,000 0,01319783 0,03150749 ! thyroid gland development GO:0030878 20 11 0,000 0,01319783 0,03147583 ! pentose-phosphate shunt GO:0006098 14 11 0,000 0,01319783 0,03144423 GO:0006740|NADPH regeneration, ! regulation of phosphatase activity GO:0010921 23 11 0,000 0,01319783 0,03141269 ! non-recombinational repair GO:0000726 19 11 0,000 0,01319783 0,03138121 GO:0006303|double-strand break repair via nonhomologous end joining, ! synapsis GO:0007129 15 11 0,000 0,01319783 0,0313498 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 11 11 0,000 0,01319783 0,03131845 ! Golgi vesicle budding GO:0048194 18 11 0,000 0,01319783 0,03128716 ! elastic fiber assembly GO:0048251 17 11 0,000 0,01319783 0,03125594 ! regulation of positive chemotaxis GO:0050926 19 11 0,000 0,01319783 0,03122477 GO:0050927|positive regulation of positive chemotaxis, ! regulation of glycolysis GO:0006110 18 11 0,000 0,01319783 0,03119367 ! dopamine receptor signaling pathway GO:0007212 25 11 0,000 0,01319783 0,03116264 ! regulation of cell projection assembly GO:0060491 22 11 0,000 0,01319783 0,03113166 ! positive regulation of lipid metabolic process GO:0045834 15 11 0,000 0,01319783 0,03110074 ! bone resorption GO:0045453 16 11 0,000 0,01319783 0,03106989 ! regulation of chemokine biosynthetic process GO:0045073 13 11 0,000 0,01319783 0,0310391 ! peptide or protein amino-terminal blocking GO:0018409 16 11 0,000 0,01319783 0,03100837 ! ventral spinal cord development GO:0021517 15 11 0,000 0,01319783 0,03097769 ! regulated secretory pathway GO:0045055 15 11 0,000 0,01319783 0,03094708 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 19 11 0,000 0,01319783 0,03091653 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! regulation of catecholamine secretion GO:0050433 21 11 0,000 0,01319783 0,03088604 ! syncytium formation GO:0006949 15 11 0,000 0,01319783 0,03085561 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01319783 0,03082525 ! glucan biosynthetic process GO:0009250 14 11 0,000 0,01319783 0,03079494 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 16 11 0,000 0,01319783 0,03076468 ! Golgi organization GO:0007030 19 11 0,000 0,01319783 0,03073449 ! response to X-ray GO:0010165 19 11 0,000 0,01319783 0,03070436 ! retinoic acid receptor signaling pathway GO:0048384 16 11 0,000 0,01319783 0,03067429 ! adult heart development GO:0007512 12 11 0,000 0,01319783 0,03064428 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01319783 0,03061432 ! epithelial cell development GO:0002064 16 11 0,000 0,01319783 0,03058442 ! actin cytoskeleton reorganization GO:0031532 20 11 0,000 0,01319783 0,03055458 ! temperature homeostasis GO:0001659 16 11 0,000 0,01319783 0,0305248 ! L-glutamate transport GO:0015813 15 11 0,000 0,01319783 0,03049508 GO:0015800|acidic amino acid transport, ! positive regulation vascular endothelial growth factor production GO:0010575 19 11 0,000 0,01319783 0,03046542 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01319783 0,03043581 ! motor axon guidance GO:0008045 17 11 0,000 0,01319783 0,03040626 ! copper ion homeostasis GO:0055070 15 11 0,000 0,01319783 0,03037677 ! protein targeting to peroxisome GO:0006625 21 11 0,000 0,01319783 0,03034733 ! regulation of bone resorption GO:0045124 27 11 0,000 0,01319783 0,03031796 ! stem cell development GO:0048864 30 11 0,000 0,01319783 0,03028864 GO:0019827|stem cell maintenance, ! alpha-beta T cell activation GO:0046631 18 11 0,000 0,01319783 0,03025937 ! negative regulation of axonogenesis GO:0050771 26 11 0,000 0,01319783 0,03023016 ! regulation of phagocytosis GO:0050764 16 11 0,000 0,01319783 0,03020101 ! regulation of insulin receptor signaling pathway GO:0046626 17 11 0,000 0,01319783 0,03017192 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01319783 0,03014288 ! nucleoside triphosphate catabolic process GO:0009143 16 11 0,000 0,01319783 0,03011389 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01319783 0,03008497 ! synaptic vesicle exocytosis GO:0016079 16 11 0,000 0,01319783 0,03005609 ! regulation of B cell differentiation GO:0045577 23 11 0,000 0,01319783 0,03002728 ! cranial nerve development GO:0021545 14 11 0,000 0,01319783 0,02999851 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01319783 0,02996981 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01319783 0,02994116 ! salivary gland development GO:0007431 24 11 0,000 0,01319783 0,02991256 ! negative regulation of neurological system process GO:0031645 20 11 0,000 0,01319783 0,02988402 ! regulation of leukocyte migration GO:0002685 25 11 0,000 0,01319783 0,02985553 ! musculoskeletal movement GO:0050881 16 11 0,000 0,01319783 0,02982709 GO:0050879|multicellular organismal movement, ! nitric oxide mediated signal transduction GO:0007263 20 11 0,000 0,01319783 0,02979871 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01319783 0,02977039 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01319783 0,02974212 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 19 11 0,000 0,01319783 0,0297139 ! cholesterol efflux GO:0033344 20 11 0,000 0,01319783 0,02968573 ! digestive tract morphogenesis GO:0048546 16 11 0,000 0,01319783 0,02965762 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 11 0,000 0,01319783 0,02962956 ! thyroid hormone metabolic process GO:0042403 17 11 0,000 0,01319783 0,02960156 ! leukocyte mediated cytotoxicity GO:0001909 18 11 0,000 0,01319783 0,02957361 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01319783 0,02954571 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 21 11 0,000 0,01319783 0,02951786 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01319783 0,02949007 ! regulation of actin filament bundle formation GO:0032231 25 11 0,000 0,01319783 0,02946232 ! cardiac cell differentiation GO:0035051 18 11 0,000 0,01319783 0,02943463 ! defense response to fungus GO:0050832 13 11 0,000 0,01319783 0,02940699 ! lysogeny GO:0030069 20 11 0,000 0,01319783 0,02937941 GO:0019047|provirus integration, ! T cell receptor signaling pathway GO:0050852 22 11 0,000 0,01319783 0,02935187 ! acrosome reaction GO:0007340 14 11 0,000 0,01319783 0,02932439 ! regulation of synapse structure and activity GO:0050803 15 11 0,000 0,01319783 0,02929696 ! regulation of steroid biosynthetic process GO:0050810 13 11 0,000 0,01319783 0,02926958 ! rRNA transcription GO:0009303 19 12 0,000 0,01438932 0,03188222 ! reproductive cellular process GO:0048610 15 12 0,000 0,01438932 0,03185248 ! regulation of membrane protein ectodomain proteolysis GO:0051043 17 12 0,000 0,01438932 0,03182279 ! pteridine and derivative biosynthetic process GO:0042559 15 12 0,000 0,01438932 0,03179316 ! dicarboxylic acid transport GO:0006835 21 12 0,000 0,01438932 0,03176359 ! phosphate transport GO:0006817 15 12 0,000 0,01438932 0,03173407 ! positive regulation of GTPase activity GO:0043547 29 12 0,000 0,01438932 0,0317046 ! peroxisomal transport GO:0043574 22 12 0,000 0,01438932 0,03167519 ! mating GO:0007618 16 12 0,000 0,01438932 0,03164583 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01438932 0,03161653 ! heart looping GO:0001947 15 12 0,000 0,01438932 0,03158729 ! negative regulation of cell-matrix adhesion GO:0001953 31 12 0,000 0,01438932 0,03155809 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 20 12 0,000 0,01438932 0,03152895 ! negative regulation of proteolysis GO:0045861 17 12 0,000 0,01438932 0,03149987 ! T cell selection GO:0045058 25 12 0,000 0,01438932 0,03147083 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01438932 0,03144186 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 17 12 0,000 0,01438932 0,03141293 ! oligodendrocyte differentiation GO:0048709 19 12 0,000 0,01438932 0,03138406 ! plasma membrane organization GO:0007009 19 12 0,000 0,01438932 0,03135524 ! focal adhesion formation GO:0048041 28 12 0,000 0,01438932 0,03132647 ! mitotic spindle organization GO:0007052 16 12 0,000 0,01438932 0,03129776 ! cellular carbohydrate catabolic process GO:0044275 14 12 0,000 0,01438932 0,0312691 ! regulation of intracellular pH GO:0051453 19 12 0,000 0,01438932 0,03124049 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01438932 0,03121193 ! monoamine transport GO:0015844 14 12 0,000 0,01438932 0,03118343 ! regulation of vascular endothelial growth factor production GO:0010574 20 12 0,000 0,01438932 0,03115498 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 18 12 0,000 0,01438932 0,03112658 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01438932 0,03109823 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01438932 0,03106993 ! regulation of organ growth GO:0046620 14 12 0,000 0,01438932 0,03104169 ! vasoconstriction GO:0042310 18 12 0,000 0,01438932 0,03101349 ! RNA-dependent DNA replication GO:0006278 16 12 0,000 0,01438932 0,03098535 ! regulation of interleukin-8 production GO:0032677 19 12 0,000 0,01438932 0,03095726 ! regulation of Rho GTPase activity GO:0032319 22 12 0,000 0,01438932 0,03092922 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01438932 0,03090123 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01438932 0,03087329 ! histone deacetylation GO:0016575 14 12 0,000 0,01438932 0,0308454 ! histone acetylation GO:0016573 27 12 0,000 0,01438932 0,03081756 ! DNA methylation GO:0006306 19 12 0,000 0,01438932 0,03078977 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 19 12 0,000 0,01438932 0,03076203 ! protein sumoylation GO:0016925 14 12 0,000 0,01438932 0,03073434 ! chromatin silencing GO:0006342 23 12 0,000 0,01438932 0,0307067 ! negative regulation of MAPKKK cascade GO:0043409 23 12 0,000 0,01438932 0,03067912 ! gland morphogenesis GO:0022612 24 12 0,000 0,01438932 0,03065158 ! regulation of hormone metabolic process GO:0032350 21 12 0,000 0,01438932 0,03062409 ! zymogen activation GO:0031638 16 12 0,000 0,01438932 0,03059664 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01438932 0,03056925 ! nucleosome positioning GO:0016584 13 12 0,000 0,01438932 0,03054191 ! T cell homeostasis GO:0043029 22 12 0,000 0,01438932 0,03051462 ! regulation of isotype switching GO:0045191 22 12 0,000 0,01438932 0,03048737 ! glutathione biosynthetic process GO:0006750 14 12 0,000 0,01438932 0,03046017 ! response to gamma radiation GO:0010332 21 12 0,000 0,01438932 0,03043303 ! regulation of osteoclast differentiation GO:0045670 18 12 0,000 0,01438932 0,03040593 ! regulation of T-helper 2 cell differentiation GO:0045628 19 12 0,000 0,01438932 0,03037888 ! aromatic amino acid family catabolic process GO:0009074 16 12 0,000 0,01438932 0,03035187 ! serine family amino acid biosynthetic process GO:0009070 16 12 0,000 0,01438932 0,03032492 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01438932 0,03029801 ! male genitalia development GO:0030539 15 12 0,000 0,01438932 0,03027115 ! regulation of cellular carbohydrate catabolic process GO:0043471 19 12 0,000 0,01438932 0,03024434 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of fatty acid oxidation GO:0046320 20 12 0,000 0,01438932 0,03021757 ! establishment or maintenance of apical/basal cell polarity GO:0035088 23 12 0,000 0,01438932 0,03019085 ! developmental induction GO:0031128 16 12 0,000 0,01438932 0,03016418 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 15 12 0,000 0,01438932 0,03013756 ! response to cold GO:0009409 15 12 0,000 0,01438932 0,03011098 ! negative regulation of immune effector process GO:0002698 20 12 0,000 0,01438932 0,03008445 ! respiratory burst GO:0045730 22 13 0,000 0,01557943 0,03254401 ! lactation GO:0007595 22 13 0,000 0,01557943 0,03251538 ! tRNA modification GO:0006400 15 13 0,000 0,01557943 0,03248681 ! negative regulation of cell projection organization GO:0031345 29 13 0,000 0,01557943 0,03245829 ! positive regulation of blood pressure GO:0045777 19 13 0,000 0,01557943 0,03242982 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01557943 0,03240139 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 20 13 0,000 0,01557943 0,03237302 ! water transport GO:0006833 21 13 0,000 0,01557943 0,0323447 GO:0042044|fluid transport, ! regulation of B cell proliferation GO:0030888 24 13 0,000 0,01557943 0,03231642 ! regulation of nitric-oxide synthase activity GO:0050999 23 13 0,000 0,01557943 0,0322882 ! copper ion transport GO:0006825 15 13 0,000 0,01557943 0,03226003 ! filopodium assembly GO:0046847 21 13 0,000 0,01557943 0,0322319 ! lipid localization GO:0010876 25 13 0,000 0,01557943 0,03220382 GO:0019915|lipid storage, ! detection of mechanical stimulus GO:0050982 17 13 0,000 0,01557943 0,0321758 ! cytokine biosynthetic process GO:0042089 17 13 0,000 0,01557943 0,03214782 ! T cell proliferation GO:0042098 24 13 0,000 0,01557943 0,03211989 ! organelle fusion GO:0048284 29 13 0,000 0,01557943 0,03209201 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01557943 0,03206417 ! endocrine pancreas development GO:0031018 19 13 0,000 0,01557943 0,03203639 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 24 13 0,000 0,01557943 0,03200865 ! platelet-derived growth factor receptor signaling pathway GO:0048008 20 13 0,000 0,01557943 0,03198096 ! photoreceptor cell maintenance GO:0045494 20 13 0,000 0,01557943 0,03195332 ! regulation of mRNA processing GO:0050684 21 13 0,000 0,01557943 0,03192573 ! regulation of skeletal muscle fiber development GO:0048742 22 13 0,000 0,01557943 0,03189818 ! methionine metabolic process GO:0006555 16 13 0,000 0,01557943 0,03187068 ! deoxyribonucleotide catabolic process GO:0009264 17 13 0,000 0,01557943 0,03184323 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01557943 0,03181583 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 21 13 0,000 0,01557943 0,03178847 ! negative regulation of endothelial cell migration GO:0010596 22 13 0,000 0,01557943 0,03176116 ! membrane protein proteolysis GO:0033619 21 13 0,000 0,01557943 0,0317339 GO:0006509|membrane protein ectodomain proteolysis, ! fear response GO:0042596 22 13 0,000 0,01557943 0,03170668 ! neutral amino acid transport GO:0015804 20 13 0,000 0,01557943 0,03167951 ! negative regulation of mitotic cell cycle GO:0045930 32 13 0,000 0,01557943 0,03165239 ! regulation of natural killer cell mediated immunity GO:0002715 21 13 0,000 0,01557943 0,03162531 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 16 13 0,000 0,01557943 0,03159828 ! positive regulation of protein import into nucleus GO:0042307 24 13 0,000 0,01557943 0,0315713 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01557943 0,03154436 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01557943 0,03151747 ! cellular pigmentation GO:0033059 24 13 0,000 0,01557943 0,03149062 ! histone methylation GO:0016571 16 13 0,000 0,01557943 0,03146382 ! regulation of epidermis development GO:0045682 21 13 0,000 0,01557943 0,03143707 ! oxygen transport GO:0015671 20 13 0,000 0,01557943 0,03141036 ! regulation of axon extension GO:0030516 26 13 0,000 0,01557943 0,03138369 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 24 13 0,000 0,01557943 0,03135707 ! detection of bacterium GO:0016045 13 13 0,000 0,01557943 0,0313305 ! L-fucose metabolic process GO:0042354 21 13 0,000 0,01557943 0,03130397 ! regulation of NF-kappaB import into nucleus GO:0042345 24 13 0,000 0,01557943 0,03127749 ! positive regulation of homeostatic process GO:0032846 19 13 0,000 0,01557943 0,03125105 ! positive regulation of protein polymerization GO:0032273 21 13 0,000 0,01557943 0,03122465 ! actin filament polymerization GO:0030041 18 13 0,000 0,01557943 0,0311983 ! regulation of protein ubiquitination GO:0031396 20 14 0,000 0,01676817 0,03355047 ! N-terminal protein amino acid modification GO:0031365 20 14 0,000 0,01676817 0,0335222 ! positive regulation of cellular catabolic process GO:0031331 24 14 0,000 0,01676817 0,03349399 ! G1 phase of mitotic cell cycle GO:0000080 24 14 0,000 0,01676817 0,03346582 ! neuron maturation GO:0042551 24 14 0,000 0,01676817 0,03343769 ! regulation of S phase GO:0033261 25 14 0,000 0,01676817 0,03340962 ! regulation of chemokine production GO:0032642 18 14 0,000 0,01676817 0,03338159 ! myotube differentiation GO:0014902 21 14 0,000 0,01676817 0,03335361 ! double-strand break repair via homologous recombination GO:0000724 24 14 0,000 0,01676817 0,03332568 GO:0000725|recombinational repair, ! negative regulation of bone remodeling GO:0046851 28 14 0,000 0,01676817 0,03329779 ! phospholipid catabolic process GO:0009395 19 14 0,000 0,01676817 0,03326995 ! aminoglycan catabolic process GO:0006026 19 14 0,000 0,01676817 0,03324215 ! vesicle targeting, to, from or within Golgi GO:0048199 19 14 0,000 0,01676817 0,0332144 ! cardiac muscle contraction GO:0060048 28 14 0,000 0,01676817 0,0331867 ! RNA polyadenylation GO:0043631 21 14 0,000 0,01676817 0,03315905 ! cartilage condensation GO:0001502 22 14 0,000 0,01676817 0,03313144 ! gene silencing by RNA GO:0031047 22 14 0,000 0,01676817 0,03310387 ! response to cAMP GO:0051591 20 14 0,000 0,01676817 0,03307636 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 17 14 0,000 0,01676817 0,03304888 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 14 0,000 0,01676817 0,03302146 ! negative regulation of cytokine biosynthetic process GO:0042036 19 14 0,000 0,01676817 0,03299408 ! limbic system development GO:0021761 25 14 0,000 0,01676817 0,03296674 ! positive regulation of ion transport GO:0043270 18 14 0,000 0,01676817 0,03293945 GO:0051928|positive regulation of calcium ion transport, ! startle response GO:0001964 21 14 0,000 0,01676817 0,03291221 ! palate development GO:0060021 19 14 0,000 0,01676817 0,03288501 ! negative regulation of gene expression, epigenetic GO:0045814 30 14 0,000 0,01676817 0,03285785 ! negative regulation of protein amino acid phosphorylation GO:0001933 31 14 0,000 0,01676817 0,03283074 ! regulation of defense response to virus GO:0050688 26 14 0,000 0,01676817 0,03280367 ! response to hexose stimulus GO:0009746 22 14 0,000 0,01676817 0,03277665 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! epidermis morphogenesis GO:0048730 31 14 0,000 0,01676817 0,03274968 ! arginine metabolic process GO:0006525 17 14 0,000 0,01676817 0,03272274 ! glutamate metabolic process GO:0006536 21 14 0,000 0,01676817 0,03269586 ! glycine metabolic process GO:0006544 22 14 0,000 0,01676817 0,03266901 ! pituitary gland development GO:0021983 24 14 0,000 0,01676817 0,03264221 ! tyrosine metabolic process GO:0006570 20 14 0,000 0,01676817 0,03261546 ! negative regulation of microtubule depolymerization GO:0007026 34 14 0,000 0,01676817 0,03258874 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 21 14 0,000 0,01676817 0,03256208 ! cytokine metabolic process GO:0042107 18 14 0,000 0,01676817 0,03253545 ! NAD metabolic process GO:0019674 25 14 0,000 0,01676817 0,03250887 ! regulation of ion transmembrane transporter activity GO:0032412 19 14 0,000 0,01676817 0,03248233 ! regulation of heart rate GO:0002027 26 14 0,000 0,01676817 0,03245584 ! exocrine system development GO:0035272 29 14 0,000 0,01676817 0,03242939 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,01676817 0,03240298 ! positive regulation of carbohydrate metabolic process GO:0045913 22 14 0,000 0,01676817 0,03237661 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! purine nucleoside monophosphate metabolic process GO:0009126 22 14 0,000 0,01676817 0,03235029 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 25 14 0,000 0,01676817 0,03232401 ! axon cargo transport GO:0008088 29 14 0,000 0,01676817 0,03229777 ! positive regulation of T cell mediated immunity GO:0002711 30 14 0,000 0,01676817 0,03227158 ! genitalia development GO:0048806 18 14 0,000 0,01676817 0,03224543 ! regulation of interleukin-12 production GO:0032655 20 14 0,000 0,01676817 0,03221932 ! autonomic nervous system development GO:0048483 26 14 0,000 0,01676817 0,03219325 ! tissue regeneration GO:0042246 24 14 0,000 0,01676817 0,03216722 ! negative regulation of protein secretion GO:0050709 22 14 0,000 0,01676817 0,03214124 ! water homeostasis GO:0030104 23 14 0,000 0,01676817 0,0321153 ! cofactor transport GO:0051181 22 14 0,000 0,01676817 0,0320894 ! regulation of acute inflammatory response GO:0002673 21 14 0,000 0,01676817 0,03206354 ! positive regulation of T-helper cell differentiation GO:0045624 20 14 0,000 0,01676817 0,03203773 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01676817 0,03201195 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01676817 0,03198622 ! regulation of mRNA stability GO:0043488 30 14 0,000 0,01676817 0,03196053 ! cell killing GO:0001906 22 14 0,000 0,01676817 0,03193488 ! positive regulation of JNK cascade GO:0046330 22 14 0,000 0,01676817 0,03190927 ! epithelial to mesenchymal transition GO:0001837 24 14 0,000 0,01676817 0,0318837 ! negative regulation of mast cell proliferation GO:0070667 26 14 0,000 0,01676817 0,03185817 GO:0042130|negative regulation of T cell proliferation, ! mRNA 3'-end processing GO:0031124 21 14 0,000 0,01676817 0,03183269 ! microspike assembly GO:0030035 25 14 0,000 0,01676817 0,03180724 ! positive regulation of calcium-mediated signaling GO:0050850 27 14 0,000 0,01676817 0,03178183 ! regulation of skeletal muscle tissue development GO:0048641 24 15 0,000 0,01795552 0,03400515 ! superoxide anion generation GO:0042554 19 15 0,000 0,01795552 0,03397804 ! negative regulation of hormone secretion GO:0046888 22 15 0,000 0,01795552 0,03395096 ! skin development GO:0043588 28 15 0,000 0,01795552 0,03392393 ! embryonic hindlimb morphogenesis GO:0035116 28 15 0,000 0,01795552 0,03389694 ! embryonic forelimb morphogenesis GO:0035115 18 15 0,000 0,01795552 0,03387 ! inositol metabolic process GO:0006020 21 15 0,000 0,01795552 0,0338431 ! retina development in camera-type eye GO:0060041 22 15 0,000 0,01795552 0,03381624 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 22 15 0,000 0,01795552 0,03378942 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 25 15 0,000 0,01795552 0,03376265 ! regulation of transmembrane transporter activity GO:0022898 20 15 0,000 0,01795552 0,03373591 GO:0032409|regulation of transporter activity, ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,01795552 0,03370922 ! activation of MAPKK activity GO:0000186 22 15 0,000 0,01795552 0,03368258 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 18 15 0,000 0,01795552 0,03365597 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01795552 0,03362941 ! response to osmotic stress GO:0006970 23 15 0,000 0,01795552 0,03360289 ! vesicle coating GO:0006901 26 15 0,000 0,01795552 0,03357641 ! regulation of the force of heart contraction GO:0002026 24 15 0,000 0,01795552 0,03354997 ! preassembly of GPI anchor in ER membrane GO:0016254 22 15 0,000 0,01795552 0,03352357 ! positive regulation of activation of JAK2 kinase activity GO:0010535 15 15 0,000 0,01795552 0,03349722 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 23 15 0,000 0,01795552 0,0334709 ! bone mineralization GO:0030282 17 15 0,000 0,01795552 0,03344463 ! G1/S transition checkpoint GO:0031575 36 15 0,000 0,01795552 0,0334184 ! intermediate filament cytoskeleton organization GO:0045104 27 15 0,000 0,01795552 0,03339221 ! positive regulation of axonogenesis GO:0050772 21 15 0,000 0,01795552 0,03336606 ! regulation of cytokine production during immune response GO:0002718 23 15 0,000 0,01795552 0,03333995 ! T cell differentiation in the thymus GO:0033077 30 15 0,000 0,01795552 0,03331388 ! regulation of cellular pH GO:0030641 23 15 0,000 0,01795552 0,03328786 ! ribosome assembly GO:0042255 17 15 0,000 0,01795552 0,03326187 ! cerebellum development GO:0021549 19 15 0,000 0,01795552 0,03323593 ! regulation of monooxygenase activity GO:0032768 29 15 0,000 0,01795552 0,03321002 ! mRNA splice site selection GO:0006376 33 15 0,000 0,01795552 0,03318416 ! positive regulation of cytokine secretion GO:0050715 19 15 0,000 0,01795552 0,03315833 ! regulation of T-helper 2 type immune response GO:0002828 24 15 0,000 0,01795552 0,03313255 ! negative regulation of inflammatory response GO:0050728 18 15 0,000 0,01795552 0,03310681 ! sphingolipid catabolic process GO:0030149 27 15 0,000 0,01795552 0,0330811 GO:0046466|membrane lipid catabolic process, ! positive regulation of bone mineralization GO:0030501 22 15 0,000 0,01795552 0,03305544 ! regulation of erythrocyte differentiation GO:0045646 29 15 0,000 0,01795552 0,03302981 ! muscle maintenance GO:0046716 21 15 0,000 0,01795552 0,03300423 ! C21-steroid hormone biosynthetic process GO:0006700 17 15 0,000 0,01795552 0,03297868 ! activation of NF-kappaB-inducing kinase activity GO:0007250 23 15 0,000 0,01795552 0,03295318 ! intestinal absorption GO:0050892 22 15 0,000 0,01795552 0,03292771 ! regulation of ATPase activity GO:0043462 24 15 0,000 0,01795552 0,03290228 ! dopamine metabolic process GO:0042417 32 15 0,000 0,01795552 0,0328769 ! gas transport GO:0015669 23 15 0,000 0,01795552 0,03285155 ! regulation of RNA stability GO:0043487 31 15 0,000 0,01795552 0,03282624 ! organic cation transport GO:0015695 19 15 0,000 0,01795552 0,03280097 ! heme biosynthetic process GO:0006783 22 15 0,000 0,01795552 0,03277574 ! regulation of BMP signaling pathway GO:0030510 24 15 0,000 0,01795552 0,03275054 ! lymphocyte homeostasis GO:0002260 29 15 0,000 0,01795552 0,03272539 ! aromatic compound biosynthetic process GO:0019438 18 15 0,000 0,01795552 0,03270028 ! release of cytochrome c from mitochondria GO:0001836 29 15 0,000 0,01795552 0,0326752 ! cilium assembly GO:0042384 22 15 0,000 0,01795552 0,03265016 ! regulation of calcium-mediated signaling GO:0050848 28 15 0,000 0,01795552 0,03262516 ! inner ear receptor cell differentiation GO:0060113 30 15 0,000 0,01795552 0,0326002 ! peptide hormone processing GO:0016486 23 15 0,000 0,01795552 0,03257527 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 36 15 0,000 0,01795552 0,03255039 ! sulfur amino acid biosynthetic process GO:0000097 21 16 0,000 0,01914151 0,03467389 ! bone remodeling GO:0046849 24 16 0,000 0,01914151 0,03464744 ! positive regulation of nucleocytoplasmic transport GO:0046824 28 16 0,000 0,01914151 0,03462104 ! regulation of cell-cell adhesion GO:0022407 38 16 0,000 0,01914151 0,03459467 ! bile acid metabolic process GO:0008206 23 16 0,000 0,01914151 0,03456834 ! negative regulation of endothelial cell proliferation GO:0001937 33 16 0,000 0,01914151 0,03454205 ! mitotic chromosome condensation GO:0007076 26 16 0,000 0,01914151 0,0345158 ! positive regulation of cell growth GO:0030307 22 16 0,000 0,01914151 0,0344896 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01914151 0,03446343 ! centrosome cycle GO:0007098 18 16 0,000 0,01914151 0,0344373 ! cell differentiation in spinal cord GO:0021515 24 16 0,000 0,01914151 0,03441121 ! regulation of survival gene product expression GO:0045884 23 16 0,000 0,01914151 0,03438516 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 16 0,000 0,01914151 0,03435915 ! DNA integration GO:0015074 25 16 0,000 0,01914151 0,03433318 ! branching involved in ureteric bud morphogenesis GO:0001658 24 16 0,000 0,01914151 0,03430725 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 35 16 0,000 0,01914151 0,03428136 ! regulation of exocytosis GO:0017157 28 16 0,000 0,01914151 0,0342555 ! embryonic digit morphogenesis GO:0042733 20 16 0,000 0,01914151 0,03422969 ! positive regulation of biomineral formation GO:0070169 23 16 0,000 0,01914151 0,03420392 ! regulation of vasodilation GO:0042312 26 16 0,000 0,01914151 0,03417818 ! DNA replication initiation GO:0006270 26 16 0,000 0,01914151 0,03415248 ! DNA unwinding during replication GO:0006268 24 16 0,000 0,01914151 0,03412682 ! regulation of steroid metabolic process GO:0019218 23 16 0,000 0,01914151 0,0341012 ! neuron recognition GO:0008038 27 16 0,000 0,01914151 0,03407562 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 22 16 0,000 0,01914151 0,03405007 ! G1 phase GO:0051318 28 16 0,000 0,01914151 0,03402457 ! cellular amino acid derivative catabolic process GO:0042219 31 16 0,000 0,01914151 0,0339991 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,01914151 0,03397367 GO:0006626|protein targeting to mitochondrion, ! positive regulation of oxidoreductase activity GO:0051353 22 16 0,000 0,01914151 0,03394828 ! negative regulation of blood coagulation GO:0030195 21 16 0,000 0,01914151 0,03392293 ! negative regulation of tissue remodeling GO:0034104 35 16 0,000 0,01914151 0,03389761 ! NADP metabolic process GO:0006739 22 16 0,000 0,01914151 0,03387233 ! neuromuscular synaptic transmission GO:0007274 31 16 0,000 0,01914151 0,03384709 ! synaptic transmission, cholinergic GO:0007271 24 16 0,000 0,01914151 0,03382189 ! folic acid and derivative metabolic process GO:0006760 18 16 0,000 0,01914151 0,03379673 ! regulation of T-helper cell differentiation GO:0045622 25 16 0,000 0,01914151 0,0337716 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,01914151 0,03374651 ! aspartate family amino acid biosynthetic process GO:0009067 19 16 0,000 0,01914151 0,03372145 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 24 16 0,000 0,01914151 0,03369644 ! positive regulation of neuron apoptosis GO:0043525 30 16 0,000 0,01914151 0,03367146 ! regulation of blood vessel endothelial cell migration GO:0043535 37 16 0,000 0,01914151 0,03364652 ! RNA 3'-end processing GO:0031123 23 16 0,000 0,01914151 0,03362161 ! defense response to virus GO:0051607 28 16 0,000 0,01914151 0,03359675 ! peptide hormone secretion GO:0030072 26 16 0,000 0,01914151 0,03357191 ! positive regulation of protein complex assembly GO:0031334 26 17 0,000 0,02032612 0,03562325 ! regulation of lipid biosynthetic process GO:0046890 22 17 0,000 0,02032612 0,03559696 ! negative regulation of cell cycle process GO:0010948 37 17 0,000 0,02032612 0,03557071 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02032612 0,0355445 ! protein amino acid deacetylation GO:0006476 23 17 0,000 0,02032612 0,03551832 ! heterophilic cell adhesion GO:0007157 38 17 0,000 0,02032612 0,03549219 ! protein amino acid acetylation GO:0006473 33 17 0,000 0,02032612 0,03546609 ! regulation of neurotransmitter secretion GO:0046928 32 17 0,000 0,02032612 0,03544003 ! forelimb morphogenesis GO:0035136 20 17 0,000 0,02032612 0,03541401 ! negative regulation of ion transport GO:0043271 19 17 0,000 0,02032612 0,03538803 ! regulation of muscle cell differentiation GO:0051147 26 17 0,000 0,02032612 0,03536208 ! adult walking behavior GO:0007628 30 17 0,000 0,02032612 0,03533618 ! patterning of blood vessels GO:0001569 27 17 0,000 0,02032612 0,03531031 ! mechanoreceptor differentiation GO:0042490 32 17 0,000 0,02032612 0,03528448 ! cellular response to hydrogen peroxide GO:0070301 25 17 0,000 0,02032612 0,03525869 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 25 17 0,000 0,02032612 0,03523293 ! retinoid metabolic process GO:0001523 22 17 0,000 0,02032612 0,03520721 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 26 17 0,000 0,02032612 0,03518153 ! positive regulation of proteolysis GO:0045862 21 17 0,000 0,02032612 0,03515589 ! cardiac muscle tissue development GO:0048738 27 17 0,000 0,02032612 0,03513029 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02032612 0,03510472 ! protein polyubiquitination GO:0000209 31 17 0,000 0,02032612 0,03507919 ! cerebral cortex development GO:0021987 34 17 0,000 0,02032612 0,03505369 ! complement activation, alternative pathway GO:0006957 17 17 0,000 0,02032612 0,03502824 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02032612 0,03500282 ! fructose metabolic process GO:0006000 24 17 0,000 0,02032612 0,03497744 ! membrane budding GO:0006900 30 17 0,000 0,02032612 0,03495209 ! neuromuscular junction development GO:0007528 25 17 0,000 0,02032612 0,03492678 ! L-amino acid transport GO:0015807 27 17 0,000 0,02032612 0,03490151 ! regulation of protein binding GO:0043393 29 17 0,000 0,02032612 0,03487627 ! peptide secretion GO:0002790 30 17 0,000 0,02032612 0,03485107 ! stem cell differentiation GO:0048863 40 17 0,000 0,02032612 0,03482591 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02032612 0,03480078 ! intermediate filament-based process GO:0045103 29 17 0,000 0,02032612 0,03477569 ! protein export from nucleus GO:0006611 26 17 0,000 0,02032612 0,03475064 ! nucleotide-excision repair, DNA gap filling GO:0006297 23 17 0,000 0,02032612 0,03472562 ! diencephalon development GO:0021536 27 17 0,000 0,02032612 0,03470064 ! oogenesis GO:0048477 25 17 0,000 0,02032612 0,03467569 ! long-chain fatty acid transport GO:0015909 25 17 0,000 0,02032612 0,03465078 ! peptide biosynthetic process GO:0043043 22 17 0,000 0,02032612 0,0346259 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02032612 0,03460106 GO:0046467|membrane lipid biosynthetic process, ! biomineral formation GO:0031214 21 17 0,000 0,02032612 0,03457626 ! vitamin A metabolic process GO:0006776 23 17 0,000 0,02032612 0,03455149 ! steroid catabolic process GO:0006706 24 17 0,000 0,02032612 0,03452676 ! porphyrin biosynthetic process GO:0006779 24 17 0,000 0,02032612 0,03450206 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 23 17 0,000 0,02032612 0,0344774 ! nerve development GO:0021675 20 17 0,000 0,02032612 0,03445277 ! negative regulation of homeostatic process GO:0032845 29 17 0,000 0,02032612 0,03442818 ! regulation of mitotic metaphase/anaphase transition GO:0030071 33 17 0,000 0,02032612 0,03440363 ! protein secretion GO:0009306 32 18 0,000 0,02150936 0,03638041 ! regulation of glucose metabolic process GO:0010906 25 18 0,000 0,02150936 0,0363545 ! positive regulation of cell killing GO:0031343 27 18 0,000 0,02150936 0,03632862 ! negative regulation of defense response GO:0031348 21 18 0,000 0,02150936 0,03630278 ! pteridine and derivative metabolic process GO:0042558 23 18 0,000 0,02150936 0,03627698 ! positive regulation of anti-apoptosis GO:0045768 33 18 0,000 0,02150936 0,03625122 ! metencephalon development GO:0022037 25 18 0,000 0,02150936 0,03622549 ! positive regulation of hormone secretion GO:0046887 28 18 0,000 0,02150936 0,0361998 ! hormone secretion GO:0046879 28 18 0,000 0,02150936 0,03617414 ! 2'-deoxyribonucleotide metabolic process GO:0009394 24 18 0,000 0,02150936 0,03614852 GO:0019692|deoxyribose phosphate metabolic process, ! signal complex assembly GO:0007172 32 18 0,000 0,02150936 0,03612294 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 27 18 0,000 0,02150936 0,03609739 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02150936 0,03607188 ! intra-Golgi vesicle-mediated transport GO:0006891 28 18 0,000 0,02150936 0,03604641 ! protein amino acid ADP-ribosylation GO:0006471 30 18 0,000 0,02150936 0,03602097 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02150936 0,03599557 ! transcription from RNA polymerase III promoter GO:0006383 36 18 0,000 0,02150936 0,0359702 ! regulation of postsynaptic membrane potential GO:0060078 31 18 0,000 0,02150936 0,03594487 ! glial cell development GO:0021782 31 18 0,000 0,02150936 0,03591957 ! keratinization GO:0031424 19 18 0,000 0,02150936 0,03589431 ! regulation of systemic arterial blood pressure by hormone GO:0001990 27 18 0,000 0,02150936 0,03586909 GO:0050886|endocrine process, ! myoblast differentiation GO:0045445 31 18 0,000 0,02150936 0,0358439 ! inactivation of MAPK activity GO:0000188 28 18 0,000 0,02150936 0,03581875 ! negative regulation of epithelial cell proliferation GO:0050680 36 18 0,000 0,02150936 0,03579363 ! vacuolar transport GO:0007034 26 18 0,000 0,02150936 0,03576854 ! pigmentation during development GO:0048066 35 18 0,000 0,02150936 0,0357435 ! cell-substrate junction assembly GO:0007044 45 18 0,000 0,02150936 0,03571848 ! cellular macromolecular complex disassembly GO:0034623 30 18 0,000 0,02150936 0,03569351 ! cellular response to unfolded protein GO:0034620 24 18 0,000 0,02150936 0,03566856 GO:0030968|endoplasmic reticulum unfolded protein response, ! fucose metabolic process GO:0006004 27 18 0,000 0,02150936 0,03564365 ! actin filament bundle formation GO:0051017 30 18 0,000 0,02150936 0,03561878 ! body fluid secretion GO:0007589 27 18 0,000 0,02150936 0,03559394 ! regulation of dephosphorylation GO:0035303 38 18 0,000 0,02150936 0,03556914 ! NLS-bearing substrate import into nucleus GO:0006607 40 18 0,000 0,02150936 0,03554437 ! behavioral interaction between organisms GO:0051705 26 18 0,000 0,02150936 0,03551963 ! negative regulation of immune response GO:0050777 33 18 0,000 0,02150936 0,03549493 ! heart process GO:0003015 32 18 0,000 0,02150936 0,03547027 GO:0060047|heart contraction, ! regulation of T cell mediated immunity GO:0002709 39 18 0,000 0,02150936 0,03544563 ! sensory perception of pain GO:0019233 26 18 0,000 0,02150936 0,03542104 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 18 0,000 0,02150936 0,03539647 ! ribosomal small subunit biogenesis GO:0042274 22 18 0,000 0,02150936 0,03537194 ! somitogenesis GO:0001756 25 18 0,000 0,02150936 0,03534745 ! neural crest cell migration GO:0001755 28 18 0,000 0,02150936 0,03532298 ! neutrophil chemotaxis GO:0030593 26 18 0,000 0,02150936 0,03529856 ! positive regulation of intracellular transport GO:0032388 30 18 0,000 0,02150936 0,03527416 ! synaptogenesis GO:0007416 28 18 0,000 0,02150936 0,0352498 ! cell-cell junction organization GO:0045216 28 18 0,000 0,02150936 0,03522547 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02150936 0,03520118 ! purine nucleotide catabolic process GO:0006195 27 18 0,000 0,02150936 0,03517692 ! proximal/distal pattern formation GO:0009954 28 18 0,000 0,02150936 0,03515269 ! regulation of generation of precursor metabolites and energy GO:0043467 29 18 0,000 0,02150936 0,0351285 ! aromatic compound catabolic process GO:0019439 26 18 0,000 0,02150936 0,03510434 ! somatic recombination of immunoglobulin gene segments GO:0016447 28 18 0,000 0,02150936 0,03508021 ! gut development GO:0048565 29 18 0,000 0,02150936 0,03505612 ! negative regulation of leukocyte proliferation GO:0070664 35 18 0,000 0,02150936 0,03503206 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! antigen receptor-mediated signaling pathway GO:0050851 33 18 0,000 0,02150936 0,03500803 ! positive regulation of synaptic transmission GO:0050806 26 18 0,000 0,02150936 0,03498404 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 28 19 0,000 0,02269123 0,03688102 ! positive regulation of translation GO:0045727 29 19 0,000 0,02269123 0,03685578 ! positive regulation of cell size GO:0045793 26 19 0,000 0,02269123 0,03683057 ! phosphatidylinositol metabolic process GO:0046488 24 19 0,000 0,02269123 0,03680539 ! glycerol metabolic process GO:0006071 22 19 0,000 0,02269123 0,03678025 ! phosphoinositide phosphorylation GO:0046854 26 19 0,000 0,02269123 0,03675515 ! regulation of neuronal synaptic plasticity GO:0048168 37 19 0,000 0,02269123 0,03673008 ! endothelial cell migration GO:0043542 24 19 0,000 0,02269123 0,03670504 ! glycosaminoglycan biosynthetic process GO:0006024 27 19 0,000 0,02269123 0,03668004 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 23 19 0,000 0,02269123 0,03665507 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 19 0,000 0,02269123 0,03663013 ! memory GO:0007613 28 19 0,000 0,02269123 0,03660523 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 19 0,000 0,02269123 0,03658036 ! pancreas development GO:0031016 27 19 0,000 0,02269123 0,03655553 ! response to carbohydrate stimulus GO:0009743 28 19 0,000 0,02269123 0,03653073 ! DNA duplex unwinding GO:0032508 28 19 0,000 0,02269123 0,03650596 GO:0032392|DNA geometric change, ! peroxisome organization GO:0007031 30 19 0,000 0,02269123 0,03648123 ! central nervous system neuron development GO:0021954 33 19 0,000 0,02269123 0,03645653 ! polysaccharide catabolic process GO:0000272 24 19 0,000 0,02269123 0,03643186 ! actin polymerization or depolymerization GO:0008154 32 19 0,000 0,02269123 0,03640723 ! vesicle docking during exocytosis GO:0006904 25 19 0,000 0,02269123 0,03638263 ! heme metabolic process GO:0042168 29 19 0,000 0,02269123 0,03635806 ! negative regulation of protein catabolic process GO:0042177 29 19 0,000 0,02269123 0,03633353 ! response to lipopolysaccharide GO:0032496 28 19 0,000 0,02269123 0,03630903 ! response to fungus GO:0009620 21 19 0,000 0,02269123 0,03628456 ! peptide cross-linking GO:0018149 35 19 0,000 0,02269123 0,03626013 ! ventricular cardiac muscle morphogenesis GO:0055010 25 19 0,000 0,02269123 0,03623573 ! determination of left/right symmetry GO:0007368 24 19 0,000 0,02269123 0,03621136 ! prostaglandin metabolic process GO:0006693 34 19 0,000 0,02269123 0,03618702 GO:0006692|prostanoid metabolic process, ! regulation of immunoglobulin mediated immune response GO:0002889 29 19 0,000 0,02269123 0,03616272 GO:0002712|regulation of B cell mediated immunity, ! detection of chemical stimulus GO:0009593 28 19 0,000 0,02269123 0,03613845 ! vitamin transport GO:0051180 26 19 0,000 0,02269123 0,03611421 ! sarcomere organization GO:0045214 26 19 0,000 0,02269123 0,03609001 ! positive regulation of myeloid cell differentiation GO:0045639 50 19 0,000 0,02269123 0,03606584 ! regulation of immunoglobulin production GO:0002637 29 19 0,000 0,02269123 0,0360417 ! positive regulation of transmission of nerve impulse GO:0051971 27 19 0,000 0,02269123 0,03601759 ! leukotriene biosynthetic process GO:0019370 27 19 0,000 0,02269123 0,03599351 GO:0043450|alkene biosynthetic process, ! regulation of glucose import GO:0046324 23 19 0,000 0,02269123 0,03596947 GO:0010827|regulation of glucose transport, ! negative regulation of coagulation GO:0050819 25 19 0,000 0,02269123 0,03594546 ! oligosaccharide metabolic process GO:0009311 35 20 0,000 0,02387173 0,03779028 ! positive regulation of angiogenesis GO:0045766 42 20 0,000 0,02387173 0,03776508 ! determination of bilateral symmetry GO:0009855 26 20 0,000 0,02387173 0,03773992 GO:0009799|determination of symmetry, ! N-acetylglucosamine metabolic process GO:0006044 25 20 0,000 0,02387173 0,0377148 ! lipid phosphorylation GO:0046834 28 20 0,000 0,02387173 0,0376897 ! aminoglycan biosynthetic process GO:0006023 28 20 0,000 0,02387173 0,03766464 ! hindlimb morphogenesis GO:0035137 35 20 0,000 0,02387173 0,03763962 ! C21-steroid hormone metabolic process GO:0008207 25 20 0,000 0,02387173 0,03761463 ! calcium-independent cell-cell adhesion GO:0016338 23 20 0,000 0,02387173 0,03758967 ! response to alkaloid GO:0043279 34 20 0,000 0,02387173 0,03756474 ! sensory perception of taste GO:0050909 26 20 0,000 0,02387173 0,03753984 ! response to retinoic acid GO:0032526 27 20 0,000 0,02387173 0,03751498 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 20 0,000 0,02387173 0,03749016 ! cellular response to reactive oxygen species GO:0034614 32 20 0,000 0,02387173 0,03746536 ! D-ribose metabolic process GO:0006014 27 20 0,000 0,02387173 0,0374406 ! chromosome condensation GO:0030261 32 20 0,000 0,02387173 0,03741587 ! peptidyl-serine phosphorylation GO:0018105 31 20 0,000 0,02387173 0,03739117 ! sex determination GO:0007530 32 20 0,000 0,02387173 0,03736651 ! plasma membrane fusion GO:0045026 24 20 0,000 0,02387173 0,03734188 ! fatty acid beta-oxidation GO:0006635 32 20 0,000 0,02387173 0,03731728 ! positive regulation of alpha-beta T cell differentiation GO:0046638 29 20 0,000 0,02387173 0,03729271 ! cytolysis GO:0019835 21 20 0,000 0,02387173 0,03726817 ! renal system process GO:0003014 35 20 0,000 0,02387173 0,03724367 ! vasodilation GO:0042311 36 20 0,000 0,02387173 0,0372192 ! negative regulation of angiogenesis GO:0016525 38 20 0,000 0,02387173 0,03719476 ! detection of biotic stimulus GO:0009595 23 20 0,000 0,02387173 0,03717036 ! positive regulation of neurological system process GO:0031646 31 20 0,000 0,02387173 0,03714598 ! hormone transport GO:0009914 30 20 0,000 0,02387173 0,03712164 ! negative regulation of neuron differentiation GO:0045665 33 20 0,000 0,02387173 0,03709733 ! regulation of leukocyte mediated cytotoxicity GO:0001910 34 20 0,000 0,02387173 0,03707305 ! estrogen receptor signaling pathway GO:0030520 36 20 0,000 0,02387173 0,03704881 ! sperm-egg recognition GO:0035036 24 20 0,000 0,02387173 0,03702459 GO:0007339|binding of sperm to zona pellucida, ! embryonic organ morphogenesis GO:0048562 26 20 0,000 0,02387173 0,03700041 ! negative regulation of translation GO:0017148 28 20 0,000 0,02387173 0,03697626 ! cellular monovalent inorganic cation homeostasis GO:0030004 31 20 0,000 0,02387173 0,03695214 ! positive regulation of DNA replication GO:0045740 37 21 0,000 0,02505087 0,0387521 ! positive regulation of protein catabolic process GO:0045732 25 21 0,000 0,02505087 0,03872685 ! positive regulation of fibroblast proliferation GO:0048146 30 21 0,000 0,02505087 0,03870164 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,02505087 0,03867646 ! positive regulation of ossification GO:0045778 34 21 0,000 0,02505087 0,03865131 ! G2/M transition of mitotic cell cycle GO:0000086 34 21 0,000 0,02505087 0,0386262 ! iron ion transport GO:0006826 49 21 0,000 0,02505087 0,03860111 ! glucosamine metabolic process GO:0006041 26 21 0,000 0,02505087 0,03857606 ! microtubule-based transport GO:0010970 41 21 0,000 0,02505087 0,03855105 ! vesicle docking GO:0048278 28 21 0,000 0,02505087 0,03852606 ! regulation of carbohydrate metabolic process GO:0006109 31 21 0,000 0,02505087 0,03850111 GO:0010675|regulation of cellular carbohydrate metabolic process, ! ovarian follicle development GO:0001541 33 21 0,000 0,02505087 0,03847619 ! apoptotic mitochondrial changes GO:0008637 42 21 0,000 0,02505087 0,0384513 ! response to ethanol GO:0045471 38 21 0,000 0,02505087 0,03842645 ! positive regulation of epithelial cell proliferation GO:0050679 43 21 0,000 0,02505087 0,03840163 ! smooth muscle contraction GO:0006939 39 21 0,000 0,02505087 0,03837683 ! glutamine metabolic process GO:0006541 29 21 0,000 0,02505087 0,03835207 ! response to vitamin A GO:0033189 28 21 0,000 0,02505087 0,03832735 ! purine ribonucleoside metabolic process GO:0046128 30 21 0,000 0,02505087 0,03830265 GO:0042278|purine nucleoside metabolic process, ! neurotransmitter metabolic process GO:0042133 36 21 0,000 0,02505087 0,03827799 ! regulation of myeloid leukocyte differentiation GO:0002761 41 21 0,000 0,02505087 0,03825336 ! leukotriene metabolic process GO:0006691 29 21 0,000 0,02505087 0,03822876 ! regulation of vasoconstriction GO:0019229 33 21 0,000 0,02505087 0,03820419 ! glycosphingolipid metabolic process GO:0006687 35 21 0,000 0,02505087 0,03817965 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 28 21 0,000 0,02505087 0,03815514 ! regulation of fatty acid metabolic process GO:0019217 32 21 0,000 0,02505087 0,03813067 ! visual learning GO:0008542 38 21 0,000 0,02505087 0,03810623 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 38 21 0,000 0,02505087 0,03808182 ! positive regulation of inflammatory response GO:0050729 38 21 0,000 0,02505087 0,03805744 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,02505087 0,03803309 ! neuromuscular process controlling balance GO:0050885 54 21 0,000 0,02505087 0,03800877 ! negative regulation of myeloid cell differentiation GO:0045638 29 21 0,000 0,02505087 0,03798448 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,02505087 0,03796023 ! aromatic amino acid family metabolic process GO:0009072 30 21 0,000 0,02505087 0,037936 ! somatic diversification of immunoglobulins GO:0016445 31 21 0,000 0,02505087 0,03791181 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,02505087 0,03788765 ! negative regulation of T cell activation GO:0050868 35 21 0,000 0,02505087 0,03786351 ! regulation of microtubule polymerization or depolymerization GO:0031110 51 21 0,000 0,02505087 0,03783941 ! embryonic pattern specification GO:0009880 34 22 0,000 0,02622864 0,03959324 ! regulation of cell killing GO:0031341 37 22 0,000 0,02622864 0,03956807 ! regulation of anti-apoptosis GO:0045767 40 22 0,000 0,02622864 0,03954293 ! gluconeogenesis GO:0006094 26 22 0,000 0,02622864 0,03951782 ! viral genome replication GO:0019079 31 22 0,000 0,02622864 0,03949275 ! nucleotide-excision repair, DNA damage removal GO:0000718 27 22 0,000 0,02622864 0,0394677 ! protein amino acid O-linked glycosylation GO:0006493 36 22 0,000 0,02622864 0,03944269 ! protein amino acid acylation GO:0043543 42 22 0,000 0,02622864 0,03941771 ! response to vitamin GO:0033273 31 22 0,000 0,02622864 0,03939276 ! molting cycle process GO:0022404 43 22 0,000 0,02622864 0,03936785 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of neurotransmitter transport GO:0051588 41 22 0,000 0,02622864 0,03934296 ! regeneration GO:0031099 37 22 0,000 0,02622864 0,03931811 ! phototransduction GO:0007602 29 22 0,000 0,02622864 0,03929329 ! regulation of DNA recombination GO:0000018 43 22 0,000 0,02622864 0,0392685 ! regulation of smooth muscle contraction GO:0006940 38 22 0,000 0,02622864 0,03924374 ! deoxyribonucleotide metabolic process GO:0009262 29 22 0,000 0,02622864 0,03921901 ! central nervous system neuron differentiation GO:0021953 39 22 0,000 0,02622864 0,03919431 ! cholesterol biosynthetic process GO:0006695 32 22 0,000 0,02622864 0,03916965 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 22 0,000 0,02622864 0,03914501 ! regulation of interleukin-6 production GO:0032675 25 22 0,000 0,02622864 0,03912041 ! regulation of interleukin-2 production GO:0032663 38 22 0,000 0,02622864 0,03909583 ! pallium development GO:0021543 43 22 0,000 0,02622864 0,03907129 ! positive regulation of locomotion GO:0040017 40 22 0,000 0,02622864 0,03904678 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! fatty acid transport GO:0015908 33 22 0,000 0,02622864 0,0390223 ! platelet activation GO:0030168 33 22 0,000 0,02622864 0,03899785 ! proteoglycan biosynthetic process GO:0030166 33 22 0,000 0,02622864 0,03897343 ! regulation of cytokine secretion GO:0050707 30 22 0,000 0,02622864 0,03894904 ! positive regulation of osteoblast differentiation GO:0045669 37 22 0,000 0,02622864 0,03892468 ! cellular alkene metabolic process GO:0043449 30 22 0,000 0,02622864 0,03890035 ! cell-cell recognition GO:0009988 28 22 0,000 0,02622864 0,03887606 ! pyrimidine nucleoside metabolic process GO:0006213 28 22 0,000 0,02622864 0,03885179 ! water-soluble vitamin biosynthetic process GO:0042364 28 22 0,000 0,02622864 0,03882755 ! neural tube closure GO:0001843 35 22 0,000 0,02622864 0,03880335 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 26 22 0,000 0,02622864 0,03877917 ! regulation of multi-organism process GO:0043900 35 22 0,000 0,02622864 0,03875502 ! protein tetramerization GO:0051262 43 22 0,000 0,02622864 0,03873091 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 36 23 0,000 0,02740505 0,0404429 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid metabolic process GO:0000096 31 23 0,000 0,02740505 0,04041776 ! reciprocal meiotic recombination GO:0007131 41 23 0,000 0,02740505 0,04039266 ! cellular aldehyde metabolic process GO:0006081 32 23 0,000 0,02740505 0,04036759 ! positive regulation of bone remodeling GO:0046852 37 23 0,000 0,02740505 0,04034254 ! cellular polysaccharide biosynthetic process GO:0033692 29 23 0,000 0,02740505 0,04031753 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 31 23 0,000 0,02740505 0,04029255 ! dicarboxylic acid metabolic process GO:0043648 36 23 0,000 0,02740505 0,0402676 ! regulation of chemotaxis GO:0050920 41 23 0,000 0,02740505 0,04024269 ! regulation of receptor-mediated endocytosis GO:0048259 26 23 0,000 0,02740505 0,0402178 ! tube lumen formation GO:0035148 37 23 0,000 0,02740505 0,04019294 ! macromolecular complex disassembly GO:0032984 39 23 0,000 0,02740505 0,04016812 ! dendrite development GO:0016358 41 23 0,000 0,02740505 0,04014332 ! vasculogenesis GO:0001570 38 23 0,000 0,02740505 0,04011856 ! microtubule organizing center organization GO:0031023 30 23 0,000 0,02740505 0,04009382 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 50 23 0,000 0,02740505 0,04006912 ! lysosome organization GO:0007040 41 23 0,000 0,02740505 0,04004445 ! digestive system process GO:0022600 35 23 0,000 0,02740505 0,0400198 ! positive regulation of cytoskeleton organization GO:0051495 43 23 0,000 0,02740505 0,03999519 ! vesicle targeting GO:0006903 35 23 0,000 0,02740505 0,03997061 ! response to corticosteroid stimulus GO:0031960 37 23 0,000 0,02740505 0,03994606 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 36 23 0,000 0,02740505 0,03992154 ! regulation of endothelial cell migration GO:0010594 44 23 0,000 0,02740505 0,03989704 ! regulation of viral reproduction GO:0050792 33 23 0,000 0,02740505 0,03987258 ! regulation of insulin secretion GO:0050796 30 23 0,000 0,02740505 0,03984815 ! regulation of alpha-beta T cell differentiation GO:0046637 35 23 0,000 0,02740505 0,03982375 ! cardiac muscle tissue morphogenesis GO:0055008 29 23 0,000 0,02740505 0,03979938 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 42 23 0,000 0,02740505 0,03977503 ! membrane depolarization GO:0051899 40 23 0,000 0,02740505 0,03975072 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,02740505 0,03972644 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 39 23 0,000 0,02740505 0,03970219 ! regulation of ARF GTPase activity GO:0032312 35 23 0,000 0,02740505 0,03967796 ! DNA modification GO:0006304 33 23 0,000 0,02740505 0,03965377 ! collagen fibril organization GO:0030199 50 23 0,000 0,02740505 0,03962961 ! synaptic vesicle transport GO:0048489 45 23 0,000 0,02740505 0,03960547 ! peptidyl-serine modification GO:0018209 37 23 0,000 0,02740505 0,03958136 ! nerve-nerve synaptic transmission GO:0007270 42 23 0,000 0,02740505 0,03955729 ! fat-soluble vitamin metabolic process GO:0006775 29 23 0,000 0,02740505 0,03953324 ! positive regulation of B cell activation GO:0050871 36 23 0,000 0,02740505 0,03950922 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,02740505 0,03948523 ! collagen catabolic process GO:0030574 29 23 0,000 0,02740505 0,03946128 ! glutamine family amino acid catabolic process GO:0009065 34 23 0,000 0,02740505 0,03943735 ! aspartate family amino acid metabolic process GO:0009066 27 23 0,000 0,02740505 0,03941344 ! porphyrin metabolic process GO:0006778 37 23 0,000 0,02740505 0,03938957 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 39 23 0,000 0,02740505 0,03936573 ! blastocyst development GO:0001824 41 23 0,000 0,02740505 0,03934191 ! actin filament-based movement GO:0030048 37 23 0,000 0,02740505 0,03931813 ! protein stabilization GO:0050821 34 23 0,000 0,02740505 0,03929437 ! protein import into nucleus, docking GO:0000059 45 24 0,000 0,02858009 0,04095445 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 30 24 0,000 0,02858009 0,04092973 ! myelination GO:0042552 39 24 0,000 0,02858009 0,04090505 ! initiation of viral infection GO:0019059 47 24 0,000 0,02858009 0,04088039 ! regulation of transmembrane transport GO:0034762 31 24 0,000 0,02858009 0,04085576 ! leukocyte adhesion GO:0007159 49 24 0,000 0,02858009 0,04083116 ! glutamate signaling pathway GO:0007215 37 24 0,000 0,02858009 0,0408066 ! visual behavior GO:0007632 42 24 0,000 0,02858009 0,04078206 ! spinal cord development GO:0021510 41 24 0,000 0,02858009 0,04075755 ! immune response-activating cell surface receptor signaling pathway GO:0002429 39 24 0,000 0,02858009 0,04073307 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 46 24 0,000 0,02858009 0,04070862 ! multicellular organismal response to stress GO:0033555 42 24 0,000 0,02858009 0,0406842 ! regulation of nitric oxide biosynthetic process GO:0045428 42 24 0,000 0,02858009 0,04065981 ! negative regulation of DNA replication GO:0008156 39 24 0,000 0,02858009 0,04063545 ! cell aging GO:0007569 38 24 0,000 0,02858009 0,04061112 ! osteoblast differentiation GO:0001649 43 24 0,000 0,02858009 0,04058681 ! response to endoplasmic reticulum stress GO:0034976 32 24 0,000 0,02858009 0,04056254 ! response to toxin GO:0009636 38 24 0,000 0,02858009 0,04053829 ! primary neural tube formation GO:0014020 37 24 0,000 0,02858009 0,04051408 ! vitamin biosynthetic process GO:0009110 30 24 0,000 0,02858009 0,04048989 ! positive regulation of alpha-beta T cell activation GO:0046635 40 24 0,000 0,02858009 0,04046573 ! cellular response to oxidative stress GO:0034599 38 24 0,000 0,02858009 0,0404416 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 24 0,000 0,02858009 0,0404175 ! fibroblast growth factor receptor signaling pathway GO:0008543 45 24 0,000 0,02858009 0,04039343 ! pentose metabolic process GO:0019321 33 24 0,000 0,02858009 0,04036938 ! immunoglobulin production GO:0002377 37 24 0,000 0,02858009 0,04034537 GO:0002440|production of molecular mediator of immune response, ! regulation of response to biotic stimulus GO:0002831 45 24 0,000 0,02858009 0,04032138 ! positive regulation of protein secretion GO:0050714 29 24 0,000 0,02858009 0,04029742 ! positive regulation of adaptive immune response GO:0002821 44 24 0,000 0,02858009 0,04027349 ! regulation of blood coagulation GO:0030193 37 24 0,000 0,02858009 0,04024959 ! positive regulation of tissue remodeling GO:0034105 41 24 0,000 0,02858009 0,04022572 ! group transfer coenzyme metabolic process GO:0006752 29 24 0,000 0,02858009 0,04020188 ! response to molecule of bacterial origin GO:0002237 38 24 0,000 0,02858009 0,04017806 ! regulation of fibroblast proliferation GO:0048145 39 25 0,000 0,02975378 0,04180327 ! neuron fate commitment GO:0048663 38 25 0,000 0,02975378 0,04177853 ! pyruvate metabolic process GO:0006090 32 25 0,000 0,02975378 0,04175383 ! superoxide metabolic process GO:0006801 33 25 0,000 0,02975378 0,04172915 ! detection of light stimulus involved in sensory perception GO:0050962 32 25 0,000 0,02975378 0,0417045 GO:0050908|detection of light stimulus involved in visual perception, ! regulation of cell-matrix adhesion GO:0001952 57 25 0,000 0,02975378 0,04167988 GO:0010810|regulation of cell-substrate adhesion, ! mitochondrial membrane organization GO:0007006 42 25 0,000 0,02975378 0,04165529 ! vacuole organization GO:0007033 43 25 0,000 0,02975378 0,04163073 ! receptor metabolic process GO:0043112 40 25 0,000 0,02975378 0,0416062 ! barbed-end actin filament capping GO:0051016 41 25 0,000 0,02975378 0,0415817 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 35 25 0,000 0,02975378 0,04155722 ! regulation of behavior GO:0050795 45 25 0,000 0,02975378 0,04153278 ! hydrogen peroxide metabolic process GO:0042743 35 25 0,000 0,02975378 0,04150836 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 45 25 0,000 0,02975378 0,04148397 ! lymphocyte proliferation GO:0046651 42 25 0,000 0,02975378 0,04145961 ! negative regulation of phosphorylation GO:0042326 46 25 0,000 0,02975378 0,04143528 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,02975378 0,04141098 ! regulation of tumor necrosis factor production GO:0032680 32 25 0,000 0,02975378 0,04138671 ! leukocyte homeostasis GO:0001776 40 25 0,000 0,02975378 0,04136246 ! positive regulation of nuclear division GO:0051785 41 25 0,000 0,02975378 0,04133824 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 38 25 0,000 0,02975378 0,04131405 ! camera-type eye morphogenesis GO:0048593 43 25 0,000 0,02975378 0,04128989 ! negative regulation of catabolic process GO:0009895 37 25 0,000 0,02975378 0,04126576 ! regulation of amine transport GO:0051952 44 25 0,000 0,02975378 0,04124166 ! liver development GO:0001889 44 25 0,000 0,02975378 0,04121758 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 38 26 0,000 0,03092611 0,0428166 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 31 26 0,000 0,03092611 0,04279163 ! positive regulation of cell projection organization GO:0031346 43 26 0,000 0,03092611 0,0427667 ! regulation of cellular catabolic process GO:0031329 39 26 0,000 0,03092611 0,04274179 ! regulation of interferon-gamma production GO:0032649 33 26 0,000 0,03092611 0,04271691 ! cellular iron ion homeostasis GO:0006879 47 26 0,000 0,03092611 0,04269206 ! epidermal growth factor receptor signaling pathway GO:0007173 42 26 0,000 0,03092611 0,04266724 ! amino sugar metabolic process GO:0006040 32 26 0,000 0,03092611 0,04264245 ! odontogenesis of dentine-containing tooth GO:0042475 43 26 0,000 0,03092611 0,04261768 ! insulin receptor signaling pathway GO:0008286 48 26 0,000 0,03092611 0,04259295 ! sperm motility GO:0030317 31 26 0,000 0,03092611 0,04256824 ! ER-nuclear signaling pathway GO:0006984 33 26 0,000 0,03092611 0,04254356 ! peptidyl-tyrosine phosphorylation GO:0018108 42 26 0,000 0,03092611 0,04251892 ! male gonad development GO:0008584 39 26 0,000 0,03092611 0,0424943 ! neural crest cell development GO:0014032 44 26 0,000 0,03092611 0,0424697 GO:0014033|neural crest cell differentiation, ! base-excision repair GO:0006284 35 26 0,000 0,03092611 0,04244514 ! cell fate determination GO:0001709 54 26 0,000 0,03092611 0,04242061 ! regulation of chromosome organization GO:0033044 37 26 0,000 0,03092611 0,0423961 ! regulation of oxidoreductase activity GO:0051341 42 26 0,000 0,03092611 0,04237162 ! detection of visible light GO:0009584 33 26 0,000 0,03092611 0,04234717 ! spermatid development GO:0007286 40 26 0,000 0,03092611 0,04232275 ! regulation of bone mineralization GO:0030500 38 26 0,000 0,03092611 0,04229836 ! regulation of osteoblast differentiation GO:0045667 41 26 0,000 0,03092611 0,04227399 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,03209707 0,04384937 ! spliceosomal snRNP biogenesis GO:0000387 38 27 0,000 0,03209707 0,04382414 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 47 27 0,000 0,03209707 0,04379894 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 42 27 0,000 0,03209707 0,04377377 ! membrane docking GO:0022406 40 27 0,000 0,03209707 0,04374863 ! circadian rhythm GO:0007623 44 27 0,000 0,03209707 0,04372351 ! regulation of endothelial cell proliferation GO:0001936 52 27 0,000 0,03209707 0,04369843 ! fat cell differentiation GO:0045444 41 27 0,000 0,03209707 0,04367337 ! positive regulation of innate immune response GO:0045089 34 27 0,000 0,03209707 0,04364834 ! myofibril assembly GO:0030239 40 27 0,000 0,03209707 0,04362334 GO:0055002|striated muscle cell development, ! negative regulation of phosphorus metabolic process GO:0010563 51 27 0,000 0,03209707 0,04359837 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 38 27 0,000 0,03209707 0,04357343 ! peptide transport GO:0015833 46 27 0,000 0,03209707 0,04354852 ! regulation of peptide secretion GO:0002791 39 27 0,000 0,03209707 0,04352363 ! negative regulation of cell development GO:0010721 67 27 0,000 0,03209707 0,04349878 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 46 27 0,000 0,03209707 0,04347395 ! positive regulation of leukocyte mediated immunity GO:0002705 45 27 0,000 0,03209707 0,04344915 GO:0002708|positive regulation of lymphocyte mediated immunity, ! phospholipid transport GO:0015914 40 27 0,000 0,03209707 0,04342438 ! detection of light stimulus GO:0009583 35 27 0,000 0,03209707 0,04339963 ! glutathione metabolic process GO:0006749 35 27 0,000 0,03209707 0,04337492 ! lipid oxidation GO:0034440 39 27 0,000 0,03209707 0,04335023 GO:0019395|fatty acid oxidation, ! leukocyte proliferation GO:0070661 45 27 0,000 0,03209707 0,04332557 GO:0032943|mononuclear cell proliferation, ! telomere organization GO:0032200 39 27 0,000 0,03209707 0,04330094 GO:0000723|telomere maintenance, ! negative regulation of neuron apoptosis GO:0043524 48 27 0,000 0,03209707 0,04327634 ! protein import into nucleus, translocation GO:0000060 47 28 0,000 0,03326669 0,04482785 ! positive regulation of smooth muscle cell proliferation GO:0048661 45 28 0,000 0,03326669 0,04480241 ! translational initiation GO:0006413 48 28 0,000 0,03326669 0,044777 ! negative regulation of actin filament depolymerization GO:0030835 44 28 0,000 0,03326669 0,04475161 ! regulation of pH GO:0006885 40 28 0,000 0,03326669 0,04472626 ! negative regulation of protein modification process GO:0031400 56 28 0,000 0,03326669 0,04470093 ! catechol metabolic process GO:0009712 46 28 0,000 0,03326669 0,04467563 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 43 28 0,000 0,03326669 0,04465037 ! cellular carbohydrate biosynthetic process GO:0034637 37 28 0,000 0,03326669 0,04462513 ! iron ion homeostasis GO:0055072 49 28 0,000 0,03326669 0,04459991 ! regulation of biomineral formation GO:0070167 40 28 0,000 0,03326669 0,04457473 ! peptidyl-tyrosine modification GO:0018212 44 28 0,000 0,03326669 0,04454957 ! neurotransmitter secretion GO:0007269 41 28 0,000 0,03326669 0,04452445 ! negative regulation of transcription regulator activity GO:0090048 48 28 0,000 0,03326669 0,04449935 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of lymphocyte activation GO:0051250 48 28 0,000 0,03326669 0,04447428 ! gene silencing GO:0016458 47 28 0,000 0,03326669 0,04444924 ! regulation of coagulation GO:0050818 42 28 0,000 0,03326669 0,04442422 ! negative regulation of actin filament polymerization GO:0030837 45 29 0,000 0,03443494 0,04595845 ! phenol metabolic process GO:0018958 47 29 0,000 0,03443494 0,04593262 ! positive regulation of cell adhesion GO:0045785 54 29 0,000 0,03443494 0,04590681 ! icosanoid biosynthetic process GO:0046456 45 29 0,000 0,03443494 0,04588103 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 39 29 0,000 0,03443494 0,04585529 ! calcium-dependent cell-cell adhesion GO:0016339 36 29 0,000 0,03443494 0,04582957 ! negative regulation of response to external stimulus GO:0032102 39 29 0,000 0,03443494 0,04580388 ! cholesterol transport GO:0030301 48 29 0,000 0,03443494 0,04577822 GO:0015918|sterol transport, ! cholesterol homeostasis GO:0042632 53 29 0,000 0,03443494 0,04575259 GO:0055092|sterol homeostasis, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 39 29 0,000 0,03443494 0,04572699 ! GPI anchor metabolic process GO:0006505 47 29 0,000 0,03443494 0,04570141 ! complement activation, classical pathway GO:0006958 39 29 0,000 0,03443494 0,04567586 ! multicellular organismal catabolic process GO:0044243 36 29 0,000 0,03443494 0,04565035 ! respiratory gaseous exchange GO:0007585 51 29 0,000 0,03443494 0,04562486 ! triglyceride metabolic process GO:0006641 38 29 0,000 0,03443494 0,0455994 ! response to ionizing radiation GO:0010212 55 29 0,000 0,03443494 0,04557397 ! muscle cell development GO:0055001 42 29 0,000 0,03443494 0,04554856 ! response to organic cyclic substance GO:0014070 53 29 0,000 0,03443494 0,04552319 ! regulation of systemic arterial blood pressure GO:0003073 52 29 0,000 0,03443494 0,04549784 ! mesoderm formation GO:0001707 52 29 0,000 0,03443494 0,04547252 ! response to estradiol stimulus GO:0032355 38 29 0,000 0,03443494 0,04544723 ! positive regulation of MAPKKK cascade GO:0043410 45 29 0,000 0,03443494 0,04542197 ! regulation of microtubule cytoskeleton organization GO:0070507 61 29 0,000 0,03443494 0,04539673 ! ensheathment of neurons GO:0007272 48 29 0,000 0,03443494 0,04537153 GO:0008366|axon ensheathment, ! serine family amino acid metabolic process GO:0009069 41 29 0,000 0,03443494 0,04534635 ! spermatid differentiation GO:0048515 45 29 0,000 0,03443494 0,0453212 ! myeloid leukocyte activation GO:0002274 44 29 0,000 0,03443494 0,04529608 ! neural tube formation GO:0001841 46 29 0,000 0,03443494 0,04527098 ! regulation of actin filament depolymerization GO:0030834 47 30 0,000 0,03560185 0,04677917 ! organic anion transport GO:0015711 50 30 0,000 0,03560185 0,04675329 ! cell junction assembly GO:0034329 65 30 0,000 0,03560185 0,04672743 ! acute-phase response GO:0006953 49 30 0,000 0,03560185 0,0467016 ! segmentation GO:0035282 43 30 0,000 0,03560185 0,04667579 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 56 30 0,000 0,03560185 0,04665002 ! negative regulation of protein kinase cascade GO:0010741 58 30 0,000 0,03560185 0,04662428 ! immune response-activating signal transduction GO:0002757 45 30 0,000 0,03560185 0,04659856 ! regulation of production of molecular mediator of immune response GO:0002700 47 30 0,000 0,03560185 0,04657287 ! ceramide metabolic process GO:0006672 47 30 0,000 0,03560185 0,04654721 ! formation of primary germ layer GO:0001704 54 30 0,000 0,03560185 0,04652158 ! nicotinamide metabolic process GO:0006769 47 30 0,000 0,03560185 0,04649598 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 50 30 0,000 0,03560185 0,0464704 ! fatty acid catabolic process GO:0009062 45 30 0,000 0,03560185 0,04644485 ! regulation of calcium ion transport GO:0051924 40 30 0,000 0,03560185 0,04641933 ! negative regulation of protein polymerization GO:0032272 47 30 0,000 0,03560185 0,04639384 ! establishment of vesicle localization GO:0051650 48 30 0,000 0,03560185 0,04636838 ! alkaloid metabolic process GO:0009820 48 31 0,000 0,0367674 0,04786015 ! response to hydrogen peroxide GO:0042542 48 31 0,000 0,0367674 0,04783391 ! post-embryonic development GO:0009791 50 31 0,000 0,0367674 0,0478077 ! inner ear morphogenesis GO:0042472 43 31 0,000 0,0367674 0,04778151 ! regulation of innate immune response GO:0045088 42 31 0,000 0,0367674 0,04775536 ! ovulation cycle process GO:0022602 46 31 0,000 0,0367674 0,04772924 ! mesoderm morphogenesis GO:0048332 54 31 0,000 0,0367674 0,04770314 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 42 31 0,000 0,0367674 0,04767707 ! immune response-regulating signal transduction GO:0002764 51 31 0,000 0,0367674 0,04765103 ! positive regulation of neurogenesis GO:0050769 49 31 0,000 0,0367674 0,04762502 ! positive regulation of T cell differentiation GO:0045582 45 31 0,000 0,0367674 0,04759904 ! positive regulation of multicellular organism growth GO:0040018 42 31 0,000 0,0367674 0,04757309 ! hexose biosynthetic process GO:0019319 37 31 0,000 0,0367674 0,04754716 ! negative regulation of MAP kinase activity GO:0043407 57 31 0,000 0,0367674 0,04752127 ! sterol biosynthetic process GO:0016126 48 31 0,000 0,0367674 0,0474954 ! biogenic amine biosynthetic process GO:0042401 45 31 0,000 0,0367674 0,04746956 ! embryonic epithelial tube formation GO:0001838 50 31 0,000 0,0367674 0,04744374 ! tissue homeostasis GO:0001894 45 31 0,000 0,0367674 0,04741796 GO:0048871|multicellular organismal homeostasis, ! mitotic sister chromatid segregation GO:0000070 47 32 0,000 0,03793161 0,04889283 ! DNA damage checkpoint GO:0000077 57 32 0,000 0,03793161 0,04886629 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 49 32 0,000 0,03793161 0,04883977 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 45 32 0,000 0,03793161 0,04881329 ! negative regulation of protein complex assembly GO:0031333 51 32 0,000 0,03793161 0,04878683 ! regulation of synaptic plasticity GO:0048167 54 32 0,000 0,03793161 0,0487604 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 32 0,000 0,03793161 0,048734 ! positive regulation of endocytosis GO:0045807 39 32 0,000 0,03793161 0,04870763 ! positive regulation of T cell proliferation GO:0042102 56 32 0,000 0,03793161 0,04868129 ! regulation of striated muscle tissue development GO:0016202 51 32 0,000 0,03793161 0,04865497 ! unsaturated fatty acid biosynthetic process GO:0006636 50 32 0,000 0,03793161 0,04862869 ! regulation of axonogenesis GO:0050770 60 32 0,000 0,03793161 0,04860243 ! telencephalon development GO:0021537 59 32 0,000 0,03793161 0,0485762 ! ovulation cycle GO:0042698 48 32 0,000 0,03793161 0,04855 ! pyridine nucleotide metabolic process GO:0019362 49 32 0,000 0,03793161 0,04852383 ! positive regulation of catabolic process GO:0009896 44 32 0,000 0,03793161 0,04849768 ! placenta development GO:0001890 45 32 0,000 0,03793161 0,04847157 ! symbiosis, encompassing mutualism through parasitism GO:0044403 52 32 0,000 0,03793161 0,04844548 ! vesicle localization GO:0051648 50 32 0,000 0,03793161 0,04841942 ! regulation of muscle development GO:0048634 52 33 0,000 0,03909446 0,04987696 ! mRNA export from nucleus GO:0006406 47 33 0,000 0,03909446 0,04985016 ! negative regulation of secretion GO:0051048 53 33 0,000 0,03909446 0,04982339 ! negative regulation of DNA metabolic process GO:0051053 53 33 0,000 0,03909446 0,04979665 ! glial cell differentiation GO:0010001 65 33 0,000 0,03909446 0,04976993 ! cellular component assembly involved in morphogenesis GO:0010927 52 33 0,000 0,03909446 0,04974325 ! sister chromatid segregation GO:0000819 48 33 0,000 0,03909446 0,04971659 ! sphingoid metabolic process GO:0046519 51 33 0,000 0,03909446 0,04968996 ! spindle organization GO:0007051 39 33 0,000 0,03909446 0,04966336 ! pigment biosynthetic process GO:0046148 55 33 0,000 0,03909446 0,04963679 ! neutral lipid metabolic process GO:0006638 45 33 0,000 0,03909446 0,04961024 GO:0006639|acylglycerol metabolic process, ! erythrocyte differentiation GO:0030218 50 33 0,000 0,03909446 0,04958373 ! protein targeting to membrane GO:0006612 63 33 0,000 0,03909446 0,04955724 ! nucleotide catabolic process GO:0009166 47 33 0,000 0,03909446 0,04953078 ! nuclear-transcribed mRNA catabolic process GO:0000956 47 33 0,000 0,03909446 0,04950435 ! leukocyte chemotaxis GO:0030595 48 33 0,000 0,03909446 0,04947795 GO:0060326|cell chemotaxis, ! BMP signaling pathway GO:0030509 49 33 0,000 0,03909446 0,04945157 ! calcium-mediated signaling GO:0019722 54 33 0,000 0,03909446 0,04942523 ! cytokine production GO:0001816 49 33 0,000 0,03909446 0,04939891 ! regulation of microtubule-based process GO:0032886 66 33 0,000 0,03909446 0,04937262 ! RNA modification GO:0009451 43 33 0,000 0,03909446 0,04934636 ! regulation of B cell activation GO:0050864 55 33 0,000 0,03909446 0,04932012 ! positive regulation of immune effector process GO:0002699 53 33 0,000 0,03909446 0,04929392 ! negative regulation of adenylate cyclase activity GO:0007194 56 34 0,000 0,04025597 0,0507315 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! ER to Golgi vesicle-mediated transport GO:0006888 57 34 0,000 0,04025597 0,05070457 ! xenobiotic metabolic process GO:0006805 49 34 0,000 0,04025597 0,05067767 ! actomyosin structure organization GO:0031032 48 34 0,000 0,04025597 0,0506508 ! embryonic skeletal system morphogenesis GO:0048704 49 34 0,000 0,04025597 0,05062396 ! monovalent inorganic cation homeostasis GO:0055067 49 34 0,000 0,04025597 0,05059715 ! positive regulation of cell development GO:0010720 58 34 0,000 0,04025597 0,05057036 ! response to mechanical stimulus GO:0009612 46 34 0,000 0,04025597 0,0505436 ! cell fate specification GO:0001708 49 34 0,000 0,04025597 0,05051688 ! peripheral nervous system development GO:0007422 58 34 0,000 0,04025597 0,05049017 ! isoprenoid metabolic process GO:0006720 47 34 0,000 0,04025597 0,0504635 ! adult locomotory behavior GO:0008344 54 34 0,000 0,04025597 0,05043686 ! monosaccharide biosynthetic process GO:0046364 40 34 0,000 0,04025597 0,05041024 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 47 35 0,000 0,04141613 0,05183569 ! phosphoinositide biosynthetic process GO:0046489 54 35 0,000 0,04141613 0,05180837 ! collagen metabolic process GO:0032963 47 35 0,000 0,04141613 0,05178107 ! cell junction organization GO:0034330 72 35 0,000 0,04141613 0,0517538 ! regulation of ARF protein signal transduction GO:0032012 56 35 0,000 0,04141613 0,05172657 ! metanephros development GO:0001656 61 35 0,000 0,04141613 0,05169936 ! positive regulation of gene-specific transcription GO:0043193 53 35 0,000 0,04141613 0,05167217 ! female gonad development GO:0008585 55 35 0,000 0,04141613 0,05164502 ! lipid homeostasis GO:0055088 63 35 0,000 0,04141613 0,0516179 ! DNA integrity checkpoint GO:0031570 61 35 0,000 0,04141613 0,0515908 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,04141613 0,05156373 ! negative regulation of hydrolase activity GO:0051346 56 35 0,000 0,04141613 0,05153669 ! hindbrain development GO:0030902 56 35 0,000 0,04141613 0,05150968 ! Rho protein signal transduction GO:0007266 53 35 0,000 0,04141613 0,0514827 ! positive regulation of lymphocyte differentiation GO:0045621 51 35 0,000 0,04141613 0,05145575 ! hormone biosynthetic process GO:0042446 49 35 0,000 0,04141613 0,05142882 ! cytokinesis GO:0000910 57 35 0,000 0,04141613 0,05140192 ! embryonic organ development GO:0048568 53 35 0,000 0,04141613 0,05137505 ! pyrimidine nucleotide metabolic process GO:0006220 48 35 0,000 0,04141613 0,05134821 ! negative regulation of cell activation GO:0050866 58 35 0,000 0,04141613 0,0513214 ! protein homooligomerization GO:0051260 59 35 0,000 0,04141613 0,05129461 ! meiosis I GO:0007127 61 36 0,000 0,04257495 0,05270232 ! negative regulation of cell adhesion GO:0007162 78 36 0,000 0,04257495 0,05267484 ! regulation of metal ion transport GO:0010959 50 36 0,000 0,04257495 0,05264739 ! development of primary male sexual characteristics GO:0046546 52 36 0,000 0,04257495 0,05261997 ! spliceosome assembly GO:0000245 65 36 0,000 0,04257495 0,05259258 ! mismatch repair GO:0006298 42 36 0,000 0,04257495 0,05256522 ! regulation of action potential in neuron GO:0019228 60 36 0,000 0,04257495 0,05253788 ! glycerol ether metabolic process GO:0006662 49 36 0,000 0,04257495 0,05251058 ! regulation of proteolysis GO:0030162 53 36 0,000 0,04257495 0,0524833 ! energy coupled proton transport, down electrochemical gradient GO:0015985 55 36 0,000 0,04257495 0,05245605 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 53 36 0,000 0,04257495 0,05242883 ! eye morphogenesis GO:0048592 64 36 0,000 0,04257495 0,05240163 ! cellular response to insulin stimulus GO:0032869 60 36 0,000 0,04257495 0,05237447 ! regulation of smooth muscle cell proliferation GO:0048660 60 37 0,000 0,04373242 0,05377049 ! positive regulation of DNA metabolic process GO:0051054 64 37 0,000 0,04373242 0,05374264 ! mammary gland development GO:0030879 73 37 0,000 0,04373242 0,05371482 ! positive regulation of JAK-STAT cascade GO:0046427 49 37 0,000 0,04373242 0,05368704 ! ear morphogenesis GO:0042471 50 37 0,000 0,04373242 0,05365928 ! odontogenesis GO:0042476 60 37 0,000 0,04373242 0,05363154 ! mitotic cell cycle checkpoint GO:0007093 74 37 0,000 0,04373242 0,05360384 ! tissue remodeling GO:0048771 65 37 0,000 0,04373242 0,05357617 ! carbohydrate homeostasis GO:0033500 45 37 0,000 0,04373242 0,05354852 GO:0042593|glucose homeostasis, ! keratinocyte differentiation GO:0030216 55 37 0,000 0,04373242 0,05352091 ! natural killer cell activation GO:0030101 45 37 0,000 0,04373242 0,05349332 ! polyol metabolic process GO:0019751 47 37 0,000 0,04373242 0,05346576 ! androgen receptor signaling pathway GO:0030521 66 37 0,000 0,04373242 0,05343823 ! glucan metabolic process GO:0044042 54 37 0,000 0,04373242 0,05341073 GO:0006073|cellular glucan metabolic process, ! positive regulation of transcription factor activity GO:0051091 57 38 0,000 0,04488856 0,05479452 GO:0090047|positive regulation of transcription regulator activity, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 48 38 0,000 0,04488856 0,05476635 GO:0006956|complement activation, ! regulation of hormone secretion GO:0046883 54 38 0,000 0,04488856 0,0547382 ! regulation of neuron projection development GO:0010975 73 38 0,000 0,04488856 0,05471009 ! feeding behavior GO:0007631 50 38 0,000 0,04488856 0,05468201 ! organic ether metabolic process GO:0018904 51 38 0,000 0,04488856 0,05465395 ! antigen processing and presentation of peptide antigen GO:0048002 67 38 0,000 0,04488856 0,05462592 ! development of primary female sexual characteristics GO:0046545 59 38 0,000 0,04488856 0,05459792 GO:0046660|female sex differentiation, ! regulation of Rab protein signal transduction GO:0032483 58 38 0,000 0,04488856 0,05456995 GO:0032313|regulation of Rab GTPase activity, ! multicellular organismal macromolecule metabolic process GO:0044259 51 38 0,000 0,04488856 0,05454201 ! ion transmembrane transport GO:0034220 58 38 0,000 0,04488856 0,0545141 ! heterocycle biosynthetic process GO:0018130 49 38 0,000 0,04488856 0,05448621 ! ribonucleoside metabolic process GO:0009119 51 38 0,000 0,04488856 0,05445836 ! neuron migration GO:0001764 59 38 0,000 0,04488856 0,05443053 ! pigment metabolic process GO:0042440 66 38 0,000 0,04488856 0,05440273 ! regulation of cell morphogenesis involved in differentiation GO:0010769 72 38 0,000 0,04488856 0,05437496 ! mRNA catabolic process GO:0006402 58 39 0,000 0,04604335 0,05574534 ! response to reactive oxygen species GO:0000302 64 39 0,000 0,04604335 0,05571692 ! establishment or maintenance of cell polarity GO:0007163 74 39 0,000 0,04604335 0,05568852 ! striated muscle cell differentiation GO:0051146 58 39 0,000 0,04604335 0,05566015 ! neural tube development GO:0021915 58 39 0,000 0,04604335 0,05563181 ! polysaccharide biosynthetic process GO:0000271 51 39 0,000 0,04604335 0,0556035 ! regulation of protein stability GO:0031647 58 39 0,000 0,04604335 0,05557522 ! female gamete generation GO:0007292 50 39 0,000 0,04604335 0,05554696 ! positive regulation of leukocyte proliferation GO:0070665 64 39 0,000 0,04604335 0,05551874 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! response to xenobiotic stimulus GO:0009410 55 39 0,000 0,04604335 0,05549054 ! protein amino acid N-linked glycosylation GO:0006487 57 40 0,000 0,04719681 0,05685179 ! Notch signaling pathway GO:0007219 64 40 0,000 0,04719681 0,05682295 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 68 40 0,000 0,04719681 0,05679413 ! monocarboxylic acid transport GO:0015718 68 40 0,000 0,04719681 0,05676535 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 71 40 0,000 0,04719681 0,05673659 ! hormone-mediated signaling GO:0009755 57 40 0,000 0,04719681 0,05670786 ! alcohol biosynthetic process GO:0046165 48 40 0,000 0,04719681 0,05667916 ! phagocytosis GO:0006909 65 40 0,000 0,04719681 0,05665049 ! mesenchymal cell development GO:0014031 70 40 0,000 0,04719681 0,05662185 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! erythrocyte homeostasis GO:0034101 60 40 0,000 0,04719681 0,05659324 ! B cell differentiation GO:0030183 70 40 0,000 0,04719681 0,05656466 ! pigmentation GO:0043473 81 40 0,000 0,04719681 0,05653611 ! developmental growth GO:0048589 70 40 0,000 0,04719681 0,05650758 ! synapse organization GO:0050808 61 40 0,000 0,04719681 0,05647909 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 61 41 0,000 0,04834893 0,05782863 ! RNA export from nucleus GO:0006405 57 41 0,000 0,04834893 0,0577995 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 72 41 0,000 0,04834893 0,0577704 ! detection of stimulus involved in sensory perception GO:0050906 55 41 0,000 0,04834893 0,05774132 ! regulation of epithelial cell proliferation GO:0050678 80 41 0,000 0,04834893 0,05771228 ! ATP synthesis coupled electron transport GO:0042773 50 41 0,000 0,04834893 0,05768326 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of protein secretion GO:0050708 55 41 0,000 0,04834893 0,05765427 ! cell growth GO:0016049 71 41 0,000 0,04834893 0,05762532 ! transforming growth factor beta receptor signaling pathway GO:0007179 59 42 0,000 0,04949971 0,05896728 ! learning GO:0007612 75 42 0,000 0,04949971 0,05893769 ! negative regulation of protein complex disassembly GO:0043242 78 42 0,000 0,04949971 0,05890813 ! cellular amide metabolic process GO:0043603 63 42 0,000 0,04949971 0,05887861 ! morphogenesis of embryonic epithelium GO:0016331 69 42 0,000 0,04949971 0,05884911 ! gliogenesis GO:0042063 85 42 0,000 0,04949971 0,05881964 ! endosome transport GO:0016197 74 42 0,000 0,04949971 0,0587902 ! induction of apoptosis by intracellular signals GO:0008629 78 42 0,000 0,04949971 0,05876079 ! male sex differentiation GO:0046661 62 42 0,000 0,04949971 0,05873141 ! double-strand break repair GO:0006302 75 42 0,000 0,04949971 0,05870206 ! epidermal cell differentiation GO:0009913 61 42 0,000 0,04949971 0,05867274 ! regulation of myeloid cell differentiation GO:0045637 78 42 0,000 0,04949971 0,05864344 ! oxidoreduction coenzyme metabolic process GO:0006733 62 42 0,000 0,04949971 0,05861418 ! mitochondrial transport GO:0006839 66 43 0,000 0,05064916 0,05994537 ! protein amino acid lipidation GO:0006497 69 43 0,000 0,05064916 0,05991549 ! energy reserve metabolic process GO:0006112 67 43 0,000 0,05064916 0,05988563 ! response to calcium ion GO:0051592 65 43 0,000 0,05064916 0,05985581 ! regulation of tube size GO:0035150 69 43 0,000 0,05064916 0,05982602 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 78 43 0,000 0,05064916 0,05979625 ! regulation of T cell proliferation GO:0042129 72 43 0,000 0,05064916 0,05976652 ! positive regulation of DNA binding GO:0043388 65 43 0,000 0,05064916 0,05973681 ! T cell differentiation GO:0030217 78 43 0,000 0,05064916 0,05970714 ! icosanoid metabolic process GO:0006690 65 43 0,000 0,05064916 0,05967749 ! amino acid activation GO:0043038 61 43 0,000 0,05064916 0,05964787 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of protein transport GO:0051222 59 43 0,000 0,05064916 0,05961829 ! G1/S transition of mitotic cell cycle GO:0000082 93 44 0,000 0,05179728 0,06093949 ! epithelial cell differentiation GO:0030855 64 44 0,000 0,05179728 0,06090929 ! receptor-mediated endocytosis GO:0006898 85 44 0,000 0,05179728 0,06087912 ! cytoskeleton-dependent intracellular transport GO:0030705 78 44 0,000 0,05179728 0,06084899 ! peptide metabolic process GO:0006518 64 44 0,000 0,05179728 0,06081888 ! multicellular organismal metabolic process GO:0044236 57 44 0,000 0,05179728 0,0607888 ! inner ear development GO:0048839 66 44 0,000 0,05179728 0,06075875 ! regulation of lymphocyte mediated immunity GO:0002706 77 44 0,000 0,05179728 0,06072873 ! regulation of gene expression, epigenetic GO:0040029 86 44 0,000 0,05179728 0,06069874 ! chromatin remodeling GO:0006338 73 44 0,000 0,05179728 0,06066878 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 58 44 0,000 0,05179728 0,06063885 ! JAK-STAT cascade GO:0007259 62 44 0,000 0,05179728 0,06060895 ! regulation of cell shape GO:0008360 83 44 0,000 0,05179728 0,06057908 ! activation of adenylate cyclase activity GO:0007190 79 45 0,000 0,05294407 0,06188979 ! positive regulation of binding GO:0051099 67 45 0,000 0,05294407 0,06185932 ! positive regulation of cell cycle GO:0045787 83 45 0,000 0,05294407 0,06182888 ! regulation of ion transport GO:0043269 60 45 0,000 0,05294407 0,06179847 ! glucose transport GO:0015758 60 45 0,000 0,05294407 0,06176808 ! neuromuscular process GO:0050905 89 45 0,000 0,05294407 0,06173773 ! positive regulation of cytokine biosynthetic process GO:0042108 61 45 0,000 0,05294407 0,06170741 ! glycosaminoglycan metabolic process GO:0030203 68 45 0,000 0,05294407 0,06167711 ! regulation of T cell differentiation GO:0045580 68 45 0,000 0,05294407 0,06164685 ! response to insulin stimulus GO:0032868 71 45 0,000 0,05294407 0,06161662 ! regulation of actin filament polymerization GO:0030833 71 46 0,000 0,05408953 0,06291885 ! regulation of JAK-STAT cascade GO:0046425 68 46 0,000 0,05408953 0,06288802 ! regulation of action potential GO:0001508 80 46 0,000 0,05408953 0,06285723 ! hexose transport GO:0008645 62 46 0,000 0,05408953 0,06282646 GO:0015749|monosaccharide transport, ! excretion GO:0007588 72 46 0,000 0,05408953 0,06279572 ! regulation of leukocyte mediated immunity GO:0002703 80 46 0,000 0,05408953 0,06276501 ! regulation of inflammatory response GO:0050727 74 46 0,000 0,05408953 0,06273434 ! epithelial tube morphogenesis GO:0060562 73 46 0,000 0,05408953 0,06270369 ! positive regulation of defense response GO:0031349 70 47 0,000 0,05523366 0,06399877 ! branching morphogenesis of a tube GO:0048754 85 47 0,000 0,05523366 0,06396753 ! embryonic skeletal system development GO:0048706 65 47 0,000 0,05523366 0,06393633 ! unsaturated fatty acid metabolic process GO:0033559 71 47 0,000 0,05523366 0,06390516 ! lipoprotein biosynthetic process GO:0042158 74 47 0,000 0,05523366 0,06387401 ! response to UV GO:0009411 79 47 0,000 0,05523366 0,0638429 ! positive regulation of adenylate cyclase activity GO:0045762 90 48 0,000 0,05637647 0,06513211 ! viral infectious cycle GO:0019058 80 48 0,000 0,05637647 0,06510042 ! leukocyte migration GO:0050900 76 48 0,000 0,05637647 0,06506875 ! cellular amino acid biosynthetic process GO:0008652 60 48 0,000 0,05637647 0,06503712 ! striated muscle contraction GO:0006941 78 48 0,000 0,05637647 0,06500552 ! vascular process in circulatory system GO:0003018 78 48 0,000 0,05637647 0,06497395 ! DNA-dependent DNA replication GO:0006261 73 48 0,000 0,05637647 0,06494241 ! tRNA processing GO:0008033 56 48 0,000 0,05637647 0,0649109 ! cell maturation GO:0048469 69 48 0,000 0,05637647 0,06487942 ! detection of abiotic stimulus GO:0009582 66 48 0,000 0,05637647 0,06484797 ! regulation of neuron apoptosis GO:0043523 84 48 0,000 0,05637647 0,06481655 ! respiratory electron transport chain GO:0022904 63 49 0,000 0,05751795 0,06609689 ! regulation of cell projection organization GO:0031344 95 49 0,000 0,05751795 0,0660649 ! glycolysis GO:0006096 63 49 0,000 0,05751795 0,06603294 ! regulation of gene-specific transcription GO:0032583 78 49 0,000 0,05751795 0,06600101 ! regulation of protein complex disassembly GO:0043244 88 49 0,000 0,05751795 0,06596911 ! endocrine system development GO:0035270 86 49 0,000 0,05751795 0,06593724 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,05751795 0,0659054 ! generation of a signal involved in cell-cell signaling GO:0003001 74 49 0,000 0,05751795 0,06587359 ! gastrulation GO:0007369 80 49 0,000 0,05751795 0,06584182 ! RNA elongation from RNA polymerase II promoter GO:0006368 65 49 0,000 0,05751795 0,06581007 ! positive regulation of cyclase activity GO:0031281 91 49 0,000 0,05751795 0,06577836 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 84 49 0,000 0,05751795 0,06574667 ! cell redox homeostasis GO:0045454 72 50 0,000 0,0586581 0,06701766 ! negative regulation of cell migration GO:0030336 105 50 0,000 0,0586581 0,06698541 ! regulation of muscle contraction GO:0006937 75 50 0,000 0,0586581 0,06695319 ! cellular polysaccharide metabolic process GO:0044264 70 50 0,000 0,0586581 0,066921 ! histone modification GO:0016570 81 50 0,000 0,0586581 0,06688884 ! positive regulation of lyase activity GO:0051349 92 50 0,000 0,0586581 0,06685671 ! heterocycle catabolic process GO:0046700 74 50 0,000 0,0586581 0,06682462 ! regulation of mast cell proliferation GO:0070666 80 50 0,000 0,0586581 0,06679255 ! RNA catabolic process GO:0006401 77 51 0,000 0,05979694 0,06805666 ! chloride transport GO:0006821 78 51 0,000 0,05979694 0,06802403 ! membrane fusion GO:0006944 82 51 0,000 0,05979694 0,06799144 ! regulation of ossification GO:0030278 82 51 0,000 0,05979694 0,06795888 ! heart morphogenesis GO:0003007 71 51 0,000 0,05979694 0,06792634 ! RNA elongation GO:0006354 67 51 0,000 0,05979694 0,06789384 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 74 51 0,000 0,05979694 0,06786137 ! aminoglycan metabolic process GO:0006022 77 52 0,000 0,06093445 0,06911924 ! activation of phospholipase C activity GO:0007202 93 52 0,000 0,06093445 0,06908622 GO:0010863|positive regulation of phospholipase C activity, ! skeletal muscle fiber development GO:0048741 79 52 0,000 0,06093445 0,06905323 ! regulation of DNA replication GO:0006275 88 52 0,000 0,06093445 0,06902027 ! immunoglobulin mediated immune response GO:0016064 72 52 0,000 0,06093445 0,06898734 GO:0019724|B cell mediated immunity, ! cell recognition GO:0008037 78 52 0,000 0,06093445 0,06895444 ! covalent chromatin modification GO:0016569 90 52 0,000 0,06093445 0,06892157 ! regulation of adaptive immune response GO:0002819 90 52 0,000 0,06093445 0,06888874 ! proton transport GO:0015992 78 52 0,000 0,06093445 0,06885593 ! negative regulation of immune system process GO:0002683 90 52 0,000 0,06093445 0,06882316 ! protein amino acid autophosphorylation GO:0046777 97 52 0,000 0,06093445 0,06879042 ! regulation of cyclin-dependent protein kinase activity GO:0000079 86 53 0,000 0,06207065 0,07003978 ! regulation of angiogenesis GO:0045765 105 53 0,000 0,06207065 0,07000649 ! muscle fiber development GO:0048747 80 53 0,000 0,06207065 0,06997323 ! sulfur compound biosynthetic process GO:0044272 71 53 0,000 0,06207065 0,06994 ! positive regulation of phospholipase activity GO:0010518 94 53 0,000 0,06207065 0,06990681 ! cytokine-mediated signaling pathway GO:0019221 77 53 0,000 0,06207065 0,06987365 ! regulation of multicellular organism growth GO:0040014 72 53 0,000 0,06207065 0,06984052 ! regulation of endocytosis GO:0030100 71 53 0,000 0,06207065 0,06980742 ! regulation of lymphocyte differentiation GO:0045619 84 53 0,000 0,06207065 0,06977435 ! glutamine family amino acid metabolic process GO:0009064 71 53 0,000 0,06207065 0,06974131 ! cellular amino acid derivative biosynthetic process GO:0042398 73 53 0,000 0,06207065 0,0697083 ! regulation of leukocyte proliferation GO:0070663 88 53 0,000 0,06207065 0,06967533 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! hydrogen transport GO:0006818 81 54 0,000 0,06320553 0,0709157 ! response to estrogen stimulus GO:0043627 88 54 0,000 0,06320553 0,07088219 ! regulation of mitosis GO:0007088 91 54 0,000 0,06320553 0,07084871 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 100 54 0,000 0,06320553 0,07081526 ! negative regulation of cytoskeleton organization GO:0051494 96 54 0,000 0,06320553 0,07078184 ! regulation of actin polymerization or depolymerization GO:0008064 81 54 0,000 0,06320553 0,07074845 ! nucleotide-excision repair GO:0006289 70 54 0,000 0,06320553 0,07071509 ! sphingolipid metabolic process GO:0006665 80 54 0,000 0,06320553 0,07068177 ! ribonucleoprotein complex assembly GO:0022618 90 54 0,000 0,06320553 0,07064848 ! morphogenesis of a branching structure GO:0001763 99 54 0,000 0,06320553 0,07061521 ! germ cell development GO:0007281 82 54 0,000 0,06320553 0,07058198 ! positive regulation of cytokine production GO:0001819 83 54 0,000 0,06320553 0,07054878 ! regulation of protein polymerization GO:0032271 84 54 0,000 0,06320553 0,07051561 ! establishment of organelle localization GO:0051656 91 54 0,000 0,06320553 0,07048248 ! glycerophospholipid biosynthetic process GO:0046474 82 55 0,000 0,06433909 0,07171285 ! ear development GO:0043583 83 55 0,000 0,06433909 0,07167918 ! regulation of phospholipase activity GO:0010517 96 55 0,000 0,06433909 0,07164554 ! regulation of protein catabolic process GO:0042176 83 55 0,000 0,06433909 0,07161194 ! integrin-mediated signaling pathway GO:0007229 93 55 0,000 0,06433909 0,07157837 ! positive regulation of lipase activity GO:0060193 96 55 0,000 0,06433909 0,07154482 ! regulation of actin filament length GO:0030832 88 56 0,000 0,06547134 0,07276978 ! positive regulation of secretion GO:0051047 83 56 0,000 0,06547134 0,07273571 ! nucleoside metabolic process GO:0009116 74 56 0,000 0,06547134 0,07270167 ! positive regulation of organelle organization GO:0010638 95 56 0,000 0,06547134 0,07266767 ! adult behavior GO:0030534 90 56 0,000 0,06547134 0,0726337 ! cartilage development GO:0051216 84 56 0,000 0,06547134 0,07259976 ! regulation of neurotransmitter levels GO:0001505 85 57 0,000 0,06660227 0,07381933 ! mesoderm development GO:0007498 84 57 0,000 0,06660227 0,07378487 ! aging GO:0007568 91 57 0,000 0,06660227 0,07375044 ! nuclear export GO:0051168 85 57 0,000 0,06660227 0,07371604 ! cellular amino acid catabolic process GO:0009063 82 57 0,000 0,06660227 0,07368167 ! single fertilization GO:0007338 67 57 0,000 0,06660227 0,07364734 ! regulation of cellular component size GO:0032535 90 58 0,000 0,06773189 0,07486156 ! lipid modification GO:0030258 82 58 0,000 0,06773189 0,07482671 ! positive regulation of growth GO:0045927 78 58 0,000 0,06773189 0,07479189 ! DNA damage response, signal transduction GO:0042770 105 58 0,000 0,06773189 0,07475711 ! membrane lipid metabolic process GO:0006643 88 58 0,000 0,06773189 0,07472235 ! negative regulation of cell motion GO:0051271 118 58 0,000 0,06773189 0,07468763 ! regulation of bone remodeling GO:0046850 102 59 0,000 0,0688602 0,07589655 ! viral reproductive process GO:0022415 99 59 0,000 0,0688602 0,07586131 ! skeletal system morphogenesis GO:0048705 90 59 0,000 0,0688602 0,07582611 ! chromosome segregation GO:0007059 93 59 0,000 0,0688602 0,07579094 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,0688602 0,0757558 ! negative regulation of response to stimulus GO:0048585 88 59 0,000 0,0688602 0,0757207 ! cell projection assembly GO:0030031 90 59 0,000 0,0688602 0,07568563 ! glucose catabolic process GO:0006007 78 60 0,000 0,06998721 0,07688872 ! regulation of lipid metabolic process GO:0019216 93 60 0,000 0,06998721 0,07685314 ! water-soluble vitamin metabolic process GO:0006767 84 60 0,000 0,06998721 0,0768176 ! response to peptide hormone stimulus GO:0043434 97 60 0,000 0,06998721 0,07678208 ! kidney development GO:0001822 101 60 0,000 0,06998721 0,0767466 ! positive regulation of cell motion GO:0051272 110 60 0,000 0,06998721 0,07671115 ! regulation of protein complex assembly GO:0043254 95 61 0,000 0,0711129 0,07790901 ! carbohydrate transport GO:0008643 83 61 0,000 0,0711129 0,07787306 ! protein maturation by peptide bond cleavage GO:0051605 86 61 0,000 0,0711129 0,07783714 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 98 62 0,000 0,07223729 0,0790314 ! amino acid transport GO:0006865 97 62 0,000 0,07223729 0,07899498 ! negative regulation of protein kinase activity GO:0006469 110 62 0,000 0,07223729 0,07895859 ! multicellular organism reproduction GO:0032504 98 62 0,000 0,07223729 0,07892224 GO:0048609|reproductive process in a multicellular organism, ! lipoprotein metabolic process GO:0042157 96 62 0,000 0,07223729 0,07888592 ! glycerolipid biosynthetic process GO:0045017 92 62 0,000 0,07223729 0,07884963 ! detection of external stimulus GO:0009581 78 62 0,000 0,07223729 0,07881338 ! regulation of tissue remodeling GO:0034103 113 62 0,000 0,07223729 0,07877716 ! secondary metabolic process GO:0019748 95 62 0,000 0,07223729 0,07874097 ! gonad development GO:0008406 91 62 0,000 0,07223729 0,07870482 ! exocytosis GO:0006887 91 63 0,000 0,07336038 0,07989178 ! negative regulation of kinase activity GO:0033673 112 63 0,000 0,07336038 0,07985513 ! oxygen and reactive oxygen species metabolic process GO:0006800 89 63 0,000 0,07336038 0,07981852 ! embryonic limb morphogenesis GO:0030326 96 63 0,000 0,07336038 0,07978194 GO:0035113|embryonic appendage morphogenesis, ! coenzyme biosynthetic process GO:0009108 81 63 0,000 0,07336038 0,07974539 ! regulation of heart contraction GO:0008016 104 63 0,000 0,07336038 0,07970888 ! developmental maturation GO:0021700 90 63 0,000 0,07336038 0,0796724 ! actin filament organization GO:0007015 107 64 0,000 0,07448216 0,08085369 ! fertilization GO:0009566 79 64 0,000 0,07448216 0,08081672 ! viral reproduction GO:0016032 104 64 0,000 0,07448216 0,08077979 ! myeloid cell differentiation GO:0030099 101 64 0,000 0,07448216 0,08074289 ! amine catabolic process GO:0009310 100 65 0,000 0,07560265 0,08192013 ! negative regulation of cell growth GO:0030308 123 65 0,000 0,07560265 0,08188274 ! camera-type eye development GO:0043010 103 65 0,000 0,07560265 0,08184538 ! steroid hormone receptor signaling pathway GO:0030518 116 65 0,000 0,07560265 0,08180806 ! regulation of lipase activity GO:0060191 117 65 0,000 0,07560265 0,08177077 ! regulation of homeostatic process GO:0032844 122 65 0,000 0,07560265 0,08173352 ! organelle localization GO:0051640 105 65 0,000 0,07560265 0,0816963 ! regulation of transcription factor activity GO:0051090 109 66 0,000 0,07672183 0,08286795 GO:0090046|regulation of transcription regulator activity, ! cellular hormone metabolic process GO:0034754 95 66 0,000 0,07672183 0,08283025 ! sensory perception of smell GO:0007608 81 66 0,000 0,07672183 0,08279259 ! regulation of cytokine biosynthetic process GO:0042035 91 66 0,000 0,07672183 0,08275495 ! cAMP-mediated signaling GO:0019933 109 66 0,000 0,07672183 0,08271735 ! lung development GO:0030324 112 66 0,000 0,07672183 0,08267979 ! lymphocyte mediated immunity GO:0002449 95 66 0,000 0,07672183 0,08264226 ! B cell activation GO:0042113 119 66 0,000 0,07672183 0,08260476 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 97 66 0,000 0,07672183 0,0825673 ! negative regulation of transferase activity GO:0051348 117 66 0,000 0,07672183 0,08252987 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 96 66 0,000 0,07672183 0,08249248 ! protein oligomerization GO:0051259 109 66 0,000 0,07672183 0,08245512 ! cell cycle checkpoint GO:0000075 123 67 0,000 0,07783971 0,08361867 ! negative regulation of cell size GO:0045792 125 67 0,000 0,07783971 0,08358083 ! neurotransmitter transport GO:0006836 92 67 0,000 0,07783971 0,08354303 ! appendage morphogenesis GO:0035107 103 67 0,000 0,07783971 0,08350526 GO:0035108|limb morphogenesis, ! fatty acid biosynthetic process GO:0006633 107 67 0,000 0,07783971 0,08346752 ! extracellular matrix organization GO:0030198 117 67 0,000 0,07783971 0,08342982 ! negative regulation of ligase activity GO:0051352 100 67 0,000 0,07783971 0,08339216 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! meiosis GO:0007126 110 68 0,000 0,0789563 0,08455022 GO:0051327|M phase of meiotic cell cycle, ! phosphoinositide metabolic process GO:0030384 100 68 0,000 0,0789563 0,08451208 ! positive regulation of protein amino acid phosphorylation GO:0001934 103 68 0,000 0,0789563 0,08447398 ! defense response to bacterium GO:0042742 79 68 0,000 0,0789563 0,08443591 ! regulation of vesicle-mediated transport GO:0060627 98 68 0,000 0,0789563 0,08439788 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 109 68 0,000 0,0789563 0,08435988 ! activation of immune response GO:0002253 93 68 0,000 0,0789563 0,08432191 ! appendage development GO:0048736 108 69 0,000 0,08007159 0,08547453 GO:0060173|limb development, ! respiratory tube development GO:0030323 117 69 0,000 0,08007159 0,08543609 ! urogenital system development GO:0001655 114 69 0,000 0,08007159 0,0853977 ! meiotic cell cycle GO:0051321 111 69 0,000 0,08007159 0,08535933 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 104 70 0,000 0,08118558 0,08650803 ! hexose catabolic process GO:0019320 95 70 0,000 0,08118558 0,0864692 ! adaptive immune response GO:0002250 102 70 0,000 0,08118558 0,08643041 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 104 71 0,000 0,08229828 0,08757571 ! cell-matrix adhesion GO:0007160 133 71 0,000 0,08229828 0,08753645 ! elevation of cytosolic calcium ion concentration GO:0007204 126 71 0,000 0,08229828 0,08749724 ! axon guidance GO:0007411 116 71 0,000 0,08229828 0,08745805 ! intracellular receptor-mediated signaling pathway GO:0030522 124 71 0,000 0,08229828 0,0874189 ! regulation of actin cytoskeleton organization GO:0032956 120 72 0,000 0,0834097 0,08855983 ! response to drug GO:0042493 115 72 0,000 0,0834097 0,08852022 ! cytosolic calcium ion homeostasis GO:0051480 128 72 0,000 0,0834097 0,08848065 ! homeostasis of number of cells GO:0048872 109 72 0,000 0,0834097 0,08844111 ! positive regulation of T cell activation GO:0050870 117 72 0,000 0,0834097 0,08840161 ! respiratory system development GO:0060541 123 72 0,000 0,0834097 0,08836215 ! rhythmic process GO:0048511 113 72 0,000 0,0834097 0,08832272 ! regulation of immune effector process GO:0002697 121 72 0,000 0,0834097 0,08828332 ! learning or memory GO:0007611 132 73 0,000 0,08451982 0,08941843 ! humoral immune response GO:0006959 93 73 0,000 0,08451982 0,08937858 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 108 73 0,000 0,08451982 0,08933877 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 110 73 0,000 0,08451982 0,08929899 ! acute inflammatory response GO:0002526 107 74 0,000 0,08562865 0,09043026 ! activation of protein kinase activity GO:0032147 115 74 0,000 0,08562865 0,09039003 ! regulation of actin filament-based process GO:0032970 122 74 0,000 0,08562865 0,09034984 ! development of primary sexual characteristics GO:0045137 107 74 0,000 0,08562865 0,09030968 ! transcription initiation from RNA polymerase II promoter GO:0006367 100 74 0,000 0,08562865 0,09026956 ! regulation of neuron differentiation GO:0045664 130 74 0,000 0,08562865 0,09022948 ! regulation of Rho protein signal transduction GO:0035023 126 74 0,000 0,08562865 0,09018943 ! regulation of synaptic transmission GO:0050804 117 74 0,000 0,08562865 0,09014942 ! leukocyte mediated immunity GO:0002443 107 75 0,000 0,0867362 0,09127494 ! positive regulation of phosphorylation GO:0042327 119 75 0,000 0,0867362 0,09123448 ! inorganic anion transport GO:0015698 109 75 0,000 0,0867362 0,09119406 ! lymphocyte differentiation GO:0030098 135 75 0,000 0,0867362 0,09115367 ! regulation of catabolic process GO:0009894 114 75 0,000 0,0867362 0,09111332 ! response to metal ion GO:0010038 114 76 0,000 0,08784246 0,09223458 ! phospholipid biosynthetic process GO:0008654 109 76 0,000 0,08784246 0,09219379 ! phosphoinositide-mediated signaling GO:0048015 122 76 0,000 0,08784246 0,09215303 ! cell-substrate adhesion GO:0031589 141 76 0,000 0,08784246 0,09211231 ! regulation of Ras GTPase activity GO:0032318 125 76 0,000 0,08784246 0,09207162 ! positive regulation of ligase activity GO:0051351 114 76 0,000 0,08784246 0,09203097 ! cellular lipid catabolic process GO:0044242 117 77 0,000 0,08894743 0,09314751 ! positive regulation of phosphorus metabolic process GO:0010562 125 77 0,000 0,08894743 0,09310642 GO:0045937|positive regulation of phosphate metabolic process, ! response to nutrient GO:0007584 114 77 0,000 0,08894743 0,09306537 ! monosaccharide catabolic process GO:0046365 104 77 0,000 0,08894743 0,09302435 ! regulation of blood pressure GO:0008217 119 78 0,000 0,09005113 0,09413715 ! muscle cell differentiation GO:0042692 117 78 0,000 0,09005113 0,09409569 ! mitochondrion organization GO:0007005 127 78 0,000 0,09005113 0,09405428 ! negative regulation of growth GO:0045926 140 78 0,000 0,09005113 0,0940129 ! amine transport GO:0015837 115 78 0,000 0,09005113 0,09397156 ! antigen processing and presentation GO:0019882 114 78 0,000 0,09005113 0,09393025 ! regulation of ubiquitin-protein ligase activity GO:0051438 123 79 0,000 0,09115354 0,09503838 ! steroid biosynthetic process GO:0006694 111 79 0,000 0,09115354 0,09499664 ! regulation of adenylate cyclase activity GO:0045761 143 80 0,000 0,09225467 0,09610199 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 123 80 0,000 0,09225467 0,09605982 ! tube morphogenesis GO:0035239 140 80 0,000 0,09225467 0,09601769 ! eye development GO:0001654 130 80 0,000 0,09225467 0,09597559 ! intracellular protein transmembrane transport GO:0065002 115 80 0,000 0,09225467 0,09593354 ! protein ubiquitination GO:0016567 135 80 0,000 0,09225467 0,09589151 ! negative regulation of organelle organization GO:0010639 136 80 0,000 0,09225467 0,09584953 ! regulation of transmission of nerve impulse GO:0051969 126 80 0,000 0,09225467 0,09580758 ! response to steroid hormone stimulus GO:0048545 129 80 0,000 0,09225467 0,09576567 ! cellular response to hormone stimulus GO:0032870 125 80 0,000 0,09225467 0,0957238 ! blood coagulation GO:0007596 129 81 0,000 0,09335452 0,09682267 GO:0050817|coagulation, ! amine biosynthetic process GO:0009309 108 81 0,000 0,09335452 0,09678038 ! response to inorganic substance GO:0010035 127 81 0,000 0,09335452 0,09673811 ! oxidative phosphorylation GO:0006119 110 81 0,000 0,09335452 0,09669589 ! nitrogen compound catabolic process GO:0044270 125 81 0,000 0,09335452 0,0966537 ! response to hypoxia GO:0001666 155 81 0,000 0,09335452 0,09661155 ! regulation of cAMP biosynthetic process GO:0030817 148 82 0,000 0,0944531 0,09770584 ! neuropeptide signaling pathway GO:0007218 101 82 0,000 0,0944531 0,09766327 ! regulation of cell morphogenesis GO:0022604 155 82 0,000 0,0944531 0,09762073 ! regulation of cyclase activity GO:0031279 146 82 0,000 0,0944531 0,09757823 ! regulation of ligase activity GO:0051340 129 82 0,000 0,0944531 0,09753577 ! cholesterol metabolic process GO:0008203 120 83 0,000 0,0955504 0,09862596 ! positive regulation of protein modification process GO:0031401 126 83 0,000 0,0955504 0,09858308 ! response to oxygen levels GO:0070482 160 83 0,000 0,0955504 0,09854024 ! regulation of cell cycle process GO:0010564 139 83 0,000 0,0955504 0,09849743 ! regulation of lyase activity GO:0051339 147 83 0,000 0,0955504 0,09845466 ! cofactor biosynthetic process GO:0051188 108 83 0,000 0,0955504 0,09841193 ! positive regulation of lymphocyte activation GO:0051251 134 83 0,000 0,0955504 0,09836924 ! regulation of cAMP metabolic process GO:0030814 153 84 0,000 0,09664642 0,09945445 ! digestion GO:0007586 111 84 0,000 0,09664642 0,09941134 ! regulation of neurological system process GO:0031644 133 84 0,000 0,09664642 0,09936827 ! ATP biosynthetic process GO:0006754 131 84 0,000 0,09664642 0,09932523 ! biogenic amine metabolic process GO:0006576 128 85 0,000 0,09774118 0,10040684 ! T cell activation GO:0042110 154 85 0,000 0,09774118 0,1003634 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 130 85 0,000 0,09774118 0,10031999 GO:0010498|proteasomal protein catabolic process, ! sex differentiation GO:0007548 126 85 0,000 0,09774118 0,10027662 ! protein import into nucleus GO:0006606 145 85 0,000 0,09774118 0,10023328 ! alcohol catabolic process GO:0046164 119 86 0,000 0,09883466 0,10131086 ! carbohydrate biosynthetic process GO:0016051 111 86 0,000 0,09883466 0,10126712 ! regulation of nucleotide biosynthetic process GO:0030808 155 87 0,000 0,09992687 0,10234202 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! hemostasis GO:0007599 138 87 0,000 0,09992687 0,10229787 ! regulation of defense response GO:0031347 135 87 0,000 0,09992687 0,10225376 ! Golgi vesicle transport GO:0048193 145 87 0,000 0,09992687 0,10220968 ! tRNA metabolic process GO:0006399 110 87 0,000 0,09992687 0,10216564 ! sensory perception of chemical stimulus GO:0007606 108 87 0,000 0,09992687 0,10212164 ! gland development GO:0048732 170 87 0,000 0,09992687 0,10207768 ! interphase of mitotic cell cycle GO:0051329 166 87 0,000 0,09992687 0,10203376 ! vitamin metabolic process GO:0006766 117 87 0,000 0,09992687 0,10198988 ! forebrain development GO:0030900 151 87 0,000 0,09992687 0,10194603 ! regulation of membrane potential GO:0042391 144 88 0,000 0,10101781 0,10301473 ! ossification GO:0001503 150 89 0,000 0,10210749 0,10408121 GO:0060348|bone development, ! nucleosome assembly GO:0006334 113 89 0,000 0,10210749 0,10403652 GO:0031497|chromatin assembly, ! interphase GO:0051325 169 89 0,000 0,10210749 0,10399187 ! regulation of DNA metabolic process GO:0051052 152 90 0,000 0,1031959 0,10505528 ! microtubule cytoskeleton organization GO:0000226 133 90 0,000 0,1031959 0,10501023 ! regulation of cyclic nucleotide metabolic process GO:0030799 161 90 0,000 0,1031959 0,10496522 ! skeletal muscle tissue development GO:0007519 135 90 0,000 0,1031959 0,10492025 GO:0060538|skeletal muscle organ development, ! transcription initiation GO:0006352 128 90 0,000 0,1031959 0,10487532 ! regulation of GTPase activity GO:0043087 149 90 0,000 0,1031959 0,10483042 ! nuclear import GO:0051170 153 90 0,000 0,1031959 0,10478556 ! positive regulation of cell activation GO:0050867 146 90 0,000 0,1031959 0,10474075 GO:0002696|positive regulation of leukocyte activation, ! carboxylic acid catabolic process GO:0046395 132 91 0,000 0,10428304 0,10579891 GO:0016054|organic acid catabolic process, ! detection of stimulus GO:0051606 123 91 0,000 0,10428304 0,1057537 ! protein localization in nucleus GO:0034504 161 92 0,000 0,10536892 0,10680925 ! sterol metabolic process GO:0016125 136 92 0,000 0,10536892 0,10676364 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 141 93 0,000 0,10645354 0,10781659 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cell cycle arrest GO:0007050 171 93 0,000 0,10645354 0,10777059 ! protein-DNA complex assembly GO:0065004 119 93 0,000 0,10645354 0,10772463 ! rRNA processing GO:0006364 124 93 0,000 0,10645354 0,10767871 ! regulation of nucleotide metabolic process GO:0006140 164 93 0,000 0,10645354 0,10763283 ! anterior/posterior pattern formation GO:0009952 141 93 0,000 0,10645354 0,10758699 ! negative regulation of multicellular organismal process GO:0051241 150 93 0,000 0,10645354 0,10754119 ! leukocyte differentiation GO:0002521 165 94 0,000 0,1075369 0,10858939 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 140 94 0,000 0,1075369 0,1085432 ! ribonucleoside triphosphate biosynthetic process GO:0009201 142 94 0,000 0,1075369 0,10849705 ! rRNA metabolic process GO:0016072 125 94 0,000 0,1075369 0,10845094 ! regulation of cell adhesion GO:0030155 187 94 0,000 0,1075369 0,10840487 ! hormone metabolic process GO:0042445 135 94 0,000 0,1075369 0,10835884 ! protein processing GO:0016485 127 94 0,000 0,1075369 0,10831285 ! nucleoside triphosphate biosynthetic process GO:0009142 143 95 0,000 0,10861901 0,10935634 ! anatomical structure homeostasis GO:0060249 152 95 0,000 0,10861901 0,10930997 ! ATP metabolic process GO:0046034 150 96 0,000 0,10969985 0,11035089 ! nucleosome organization GO:0034728 126 96 0,000 0,10969985 0,11030413 ! protein modification by small protein conjugation GO:0032446 153 96 0,000 0,10969985 0,11025741 ! female pregnancy GO:0007565 148 96 0,000 0,10969985 0,11021073 ! regulation of neurogenesis GO:0050767 179 97 0,000 0,11077944 0,11124825 ! reproductive developmental process GO:0003006 149 97 0,000 0,11077944 0,11120119 ! response to virus GO:0009615 141 98 0,000 0,11185777 0,11223615 ! polysaccharide metabolic process GO:0005976 141 98 0,000 0,11185777 0,11218871 ! Wnt receptor signaling pathway GO:0016055 161 98 0,000 0,11185777 0,11214131 ! regulation of T cell activation GO:0050863 155 98 0,000 0,11185777 0,11209396 ! glycerophospholipid metabolic process GO:0006650 143 99 0,000 0,11293485 0,11312554 ! cell fate commitment GO:0045165 165 99 0,000 0,11293485 0,11307781 ! positive regulation of immune response GO:0050778 143 99 0,000 0,11293485 0,11303011 ! sulfur metabolic process GO:0006790 136 99 0,000 0,11293485 0,11298246 ! carbohydrate catabolic process GO:0016052 137 100 0,000 0,11401068 0,11401068