pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/3178-4-real-Parker_GPL1390-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL1390.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 2,000 8,812E-09 3,147E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 51 50 3,000 1,46E-08 2,607E-05 ! cyclin-dependent protein kinase regulator activity GO:0016538 11 11 2,000 2,594E-08 3,088E-05 ! protein kinase regulator activity GO:0019887 64 64 3,000 4,013E-08 3,582E-05 ! protein serine/threonine kinase inhibitor activity GO:0030291 14 14 2,000 5,717E-08 4,083E-05 ! release of cytochrome c from mitochondria GO:0001836 14 14 2,000 5,717E-08 3,403E-05 ! kinase regulator activity GO:0019207 77 77 3,000 8,516E-08 4,344E-05 ! apoptotic mitochondrial changes GO:0008637 21 21 2,000 2,085E-07 9,305E-05 ! protein kinase inhibitor activity GO:0004860 28 28 2,000 5,124E-07 2,033E-04 ! kinase inhibitor activity GO:0019210 30 30 2,000 6,346E-07 2,266E-04 ! induction of apoptosis by intracellular signals GO:0008629 46 43 2,000 1,921E-06 6,237E-04 ! keratinocyte differentiation GO:0030216 46 43 2,000 1,921E-06 5,717E-04 ! epidermal cell differentiation GO:0009913 51 48 2,000 2,689E-06 7,385E-04 ! response to UV GO:0009411 50 49 2,000 2,863E-06 7,303E-04 ! embryonic camera-type eye development GO:0031076 7 5 1,000 3,314E-06 7,889E-04 GO:0048596|embryonic camera-type eye morphogenesis, ! MutLalpha complex binding GO:0032405 6 5 1,000 3,314E-06 7,396E-04 ! homeostasis of number of cells GO:0048872 62 58 2,000 4,782E-06 1,004E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 4,969E-06 9,858E-04 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 1,000 4,969E-06 9,339E-04 ! enucleate erythrocyte differentiation GO:0043353 6 6 1,000 4,969E-06 8,872E-04 ! superoxide-generating NADPH oxidase activity GO:0016175 6 6 1,000 4,969E-06 8,45E-04 ! DNA replication factor C complex GO:0005663 6 6 1,000 4,969E-06 8,065E-04 ! B cell homeostasis GO:0001782 7 6 1,000 4,969E-06 7,715E-04 ! definitive hemopoiesis GO:0060216 6 6 1,000 4,969E-06 7,393E-04 ! negative regulation of protein kinase activity GO:0006469 67 61 2,000 5,572E-06 7,959E-04 ! negative regulation of kinase activity GO:0033673 68 62 2,000 5,854E-06 8,04E-04 ! negative regulation of transferase activity GO:0051348 71 65 2,000 6,755E-06 8,934E-04 ! response to pH GO:0009268 7 7 1,000 6,954E-06 8,869E-04 ! regulation of activated T cell proliferation GO:0046006 8 8 1,000 9,269E-06 1,141E-03 ! keratinocyte proliferation GO:0043616 8 8 1,000 9,269E-06 1,103E-03 ! positive regulation vascular endothelial growth factor production GO:0010575 8 8 1,000 9,269E-06 1,068E-03 ! embryonic eye morphogenesis GO:0048048 10 8 1,000 9,269E-06 1,034E-03 ! neuron apoptosis GO:0051402 8 8 1,000 9,269E-06 1,003E-03 ! NADPH oxidase complex GO:0043020 8 8 1,000 9,269E-06 9,736E-04 ! T cell homeostasis GO:0043029 9 8 1,000 9,269E-06 9,457E-04 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 8 8 1,000 9,269E-06 9,195E-04 ! C-X-C chemokine receptor activity GO:0016494 8 8 1,000 9,269E-06 8,946E-04 ! respiratory burst GO:0045730 9 9 1,000 1,191E-05 1,12E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 9 9 1,000 1,191E-05 1,091E-03 ! regulation of vascular endothelial growth factor production GO:0010574 9 9 1,000 1,191E-05 1,064E-03 ! trophectodermal cell differentiation GO:0001829 9 9 1,000 1,191E-05 1,038E-03 ! negative regulation of B cell activation GO:0050869 9 9 1,000 1,191E-05 1,013E-03 ! C-X-C chemokine binding GO:0019958 9 9 1,000 1,191E-05 9,894E-04 ! mitochondrion organization GO:0007005 86 83 2,000 1,413E-05 1,147E-03 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 1,000 1,489E-05 1,181E-03 ! ER-Golgi intermediate compartment membrane GO:0033116 10 10 1,000 1,489E-05 1,156E-03 ! L-serine metabolic process GO:0006563 11 10 1,000 1,489E-05 1,131E-03 ! mismatch repair complex binding GO:0032404 11 10 1,000 1,489E-05 1,108E-03 ! regulation of intracellular pH GO:0051453 10 10 1,000 1,489E-05 1,085E-03 ! negative regulation of mast cell proliferation GO:0070667 10 10 1,000 1,489E-05 1,063E-03 GO:0042130|negative regulation of T cell proliferation, ! Rac GTPase binding GO:0048365 11 11 1,000 1,819E-05 1,274E-03 ! blastocyst formation GO:0001825 11 11 1,000 1,819E-05 1,249E-03 ! structure-specific DNA binding GO:0043566 93 92 2,000 1,926E-05 1,298E-03 ! induction of apoptosis via death domain receptors GO:0008625 12 12 1,000 2,182E-05 1,443E-03 ! lymphocyte homeostasis GO:0002260 14 12 1,000 2,182E-05 1,417E-03 ! negative regulation of caspase activity GO:0043154 12 12 1,000 2,182E-05 1,392E-03 ! superoxide anion generation GO:0042554 13 13 1,000 2,578E-05 1,615E-03 ! positive regulation of cell growth GO:0030307 13 13 1,000 2,578E-05 1,587E-03 ! NADP metabolic process GO:0006739 13 13 1,000 2,578E-05 1,56E-03 ! embryonic placenta development GO:0001892 13 13 1,000 2,578E-05 1,534E-03 ! negative regulation of leukocyte proliferation GO:0070664 13 13 1,000 2,578E-05 1,509E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! racemase and epimerase activity GO:0016854 14 14 1,000 3,007E-05 1,732E-03 ! regulation of B cell proliferation GO:0030888 18 14 1,000 3,007E-05 1,704E-03 ! regulation of cellular pH GO:0030641 14 14 1,000 3,007E-05 1,678E-03 ! skin development GO:0043588 16 15 1,000 3,468E-05 1,905E-03 ! polysome GO:0005844 16 15 1,000 3,468E-05 1,877E-03 ! negative regulation of peptidase activity GO:0010466 16 15 1,000 3,468E-05 1,849E-03 ! positive regulation of cell size GO:0045793 16 16 1,000 3,963E-05 2,081E-03 ! C-C chemokine binding GO:0019957 16 16 1,000 3,963E-05 2,051E-03 GO:0016493|C-C chemokine receptor activity, ! hemoglobin complex GO:0005833 18 17 1,000 4,489E-05 2,29E-03 ! oxygen transport GO:0015671 18 17 1,000 4,489E-05 2,258E-03 GO:0005344|oxygen transporter activity, ! negative regulation of T cell activation GO:0050868 17 17 1,000 4,489E-05 2,227E-03 ! nucleotide-excision repair, DNA gap filling GO:0006297 18 17 1,000 4,489E-05 2,196E-03 ! DNA fragmentation involved in apoptosis GO:0006309 17 17 1,000 4,489E-05 2,166E-03 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 17 17 1,000 4,489E-05 2,138E-03 ! cellular response to unfolded protein GO:0034620 21 19 1,000 5,641E-05 2,651E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! gas transport GO:0015669 20 19 1,000 5,641E-05 2,616E-03 ! cellular monovalent inorganic cation homeostasis GO:0030004 20 19 1,000 5,641E-05 2,583E-03 ! nuclear inner membrane GO:0005637 20 20 1,000 6,266E-05 2,832E-03 ! leukocyte homeostasis GO:0001776 22 20 1,000 6,266E-05 2,797E-03 ! embryonic organ morphogenesis GO:0048562 22 20 1,000 6,266E-05 2,762E-03 ! liver development GO:0001889 20 20 1,000 6,266E-05 2,729E-03 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 20 1,000 6,266E-05 2,696E-03 ! superoxide metabolic process GO:0006801 21 21 1,000 6,923E-05 2,943E-03 ! cell structure disassembly during apoptosis GO:0006921 21 21 1,000 6,923E-05 2,909E-03 ! base-excision repair GO:0006284 21 21 1,000 6,923E-05 2,875E-03 ! camera-type eye morphogenesis GO:0048593 25 22 1,000 7,613E-05 3,125E-03 ! apoptotic nuclear changes GO:0030262 23 23 1,000 8,336E-05 3,383E-03 ! nicotinamide metabolic process GO:0006769 23 23 1,000 8,336E-05 3,345E-03 GO:0046496|nicotinamide nucleotide metabolic process, ! single-stranded RNA binding GO:0003727 24 23 1,000 8,336E-05 3,307E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 24 24 1,000 9,091E-05 3,567E-03 ! G-protein chemoattractant receptor activity GO:0001637 24 24 1,000 9,091E-05 3,529E-03 GO:0004950|chemokine receptor activity, ! hydrogen peroxide metabolic process GO:0042743 24 24 1,000 9,091E-05 3,491E-03 ! calcium-dependent phospholipid binding GO:0005544 24 24 1,000 9,091E-05 3,454E-03 ! negative regulation of lymphocyte activation GO:0051250 24 24 1,000 9,091E-05 3,417E-03 ! alkaloid metabolic process GO:0009820 24 24 1,000 9,091E-05 3,382E-03 ! DNA catabolic process, endonucleolytic GO:0000737 24 24 1,000 9,091E-05 3,347E-03 ! RNA export from nucleus GO:0006405 27 25 1,000 9,878E-05 3,599E-03 ! blastocyst development GO:0001824 25 25 1,000 9,878E-05 3,563E-03 ! pyridine nucleotide metabolic process GO:0019362 26 26 1,000 1,07E-04 3,82E-03 ! chemokine binding GO:0019956 26 26 1,000 1,07E-04 3,782E-03 ! fat cell differentiation GO:0045444 26 26 1,000 1,07E-04 3,745E-03 ! response to endoplasmic reticulum stress GO:0034976 29 26 1,000 1,07E-04 3,709E-03 ! negative regulation of leukocyte activation GO:0002695 26 26 1,000 1,07E-04 3,673E-03 ! regulation of smooth muscle cell proliferation GO:0048660 27 27 1,000 1,155E-04 3,928E-03 ! ER-nuclear signaling pathway GO:0006984 31 28 1,000 1,243E-04 4,189E-03 ! Rho GTPase binding GO:0017048 32 29 1,000 1,335E-04 4,456E-03 ! serine family amino acid metabolic process GO:0009069 30 29 1,000 1,335E-04 4,415E-03 ! erythrocyte differentiation GO:0030218 32 30 1,000 1,43E-04 4,685E-03 ! negative regulation of hydrolase activity GO:0051346 32 30 1,000 1,43E-04 4,643E-03 ! negative regulation of cell activation GO:0050866 31 30 1,000 1,43E-04 4,601E-03 ! replication fork GO:0005657 32 31 1,000 1,528E-04 4,873E-03 ! placenta development GO:0001890 31 31 1,000 1,528E-04 4,829E-03 ! regulation of pH GO:0006885 31 31 1,000 1,528E-04 4,787E-03 ! NADP or NADPH binding GO:0050661 33 32 1,000 1,63E-04 5,06E-03 ! regulation of B cell activation GO:0050864 36 32 1,000 1,63E-04 5,017E-03 ! eye morphogenesis GO:0048592 38 33 1,000 1,734E-04 5,293E-03 ! embryonic organ development GO:0048568 36 33 1,000 1,734E-04 5,248E-03 ! cellular amide metabolic process GO:0043603 34 34 1,000 1,842E-04 5,527E-03 ! response to calcium ion GO:0051592 39 35 1,000 1,953E-04 5,812E-03 ! oxygen binding GO:0019825 36 35 1,000 1,953E-04 5,764E-03 ! erythrocyte homeostasis GO:0034101 37 35 1,000 1,953E-04 5,716E-03 ! oxidoreduction coenzyme metabolic process GO:0006733 37 36 1,000 2,067E-04 6,002E-03 ! regulation of T cell proliferation GO:0042129 41 37 1,000 2,185E-04 6,291E-03 ! monovalent inorganic cation homeostasis GO:0055067 39 38 1,000 2,305E-04 6,586E-03 ! positive regulation of cell cycle GO:0045787 39 39 1,000 2,429E-04 6,884E-03 ! induction of apoptosis by extracellular signals GO:0008624 39 39 1,000 2,429E-04 6,83E-03 ! ER-Golgi intermediate compartment GO:0005793 42 39 1,000 2,429E-04 6,777E-03 ! nuclear export GO:0051168 42 40 1,000 2,556E-04 7,076E-03 ! nucleus organization GO:0006997 40 40 1,000 2,556E-04 7,022E-03 ! regulation of translational initiation GO:0006446 41 41 1,000 2,686E-04 7,323E-03 ! positive regulation of cytokine production GO:0001819 42 41 1,000 2,686E-04 7,267E-03 ! positive regulation of growth GO:0045927 42 42 1,000 2,82E-04 7,571E-03 ! cellular component disassembly GO:0022411 45 44 1,000 3,096E-04 8,251E-03 ! negative regulation of immune system process GO:0002683 49 44 1,000 3,096E-04 8,19E-03 ! regulation of mast cell proliferation GO:0070666 48 44 1,000 3,096E-04 8,13E-03 ! G1/S transition of mitotic cell cycle GO:0000082 47 46 1,000 3,385E-04 8,824E-03 ! regulation of leukocyte proliferation GO:0070663 50 46 1,000 3,385E-04 8,76E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! single-stranded DNA binding GO:0003697 49 49 1,000 3,843E-04 9,873E-03 ! water-soluble vitamin metabolic process GO:0006767 50 49 1,000 3,843E-04 9,802E-03 ! nuclear periphery GO:0034399 53 50 1,000 4,002E-04 0,01013494 ! regulation of DNA replication GO:0006275 56 50 1,000 4,002E-04 0,01006357 ! DNA damage response, signal transduction GO:0042770 58 52 1,000 4,329E-04 0,01081027 ! positive regulation of protein amino acid phosphorylation GO:0001934 54 52 1,000 4,329E-04 0,0107352 ! pyridoxal phosphate binding GO:0030170 56 53 1,000 4,497E-04 0,01107573 GO:0070279|vitamin B6 binding, ! embryonic skeletal system development GO:0048706 54 53 1,000 4,497E-04 0,01099987 ! proton transport GO:0015992 53 53 1,000 4,497E-04 0,01092504 ! double-stranded DNA binding GO:0003690 55 54 1,000 4,669E-04 0,01126501 ! DNA catabolic process GO:0006308 55 54 1,000 4,669E-04 0,0111894 ! hydrogen transport GO:0006818 55 55 1,000 4,843E-04 0,01153058 ! nucleotide-excision repair GO:0006289 58 55 1,000 4,843E-04 0,01145422 ! camera-type eye development GO:0043010 59 56 1,000 5,021E-04 0,01179656 ! positive regulation of phosphorylation GO:0042327 59 57 1,000 5,202E-04 0,01214177 ! positive regulation of phosphorus metabolic process GO:0010562 61 58 1,000 5,386E-04 0,01248979 GO:0045937|positive regulation of phosphate metabolic process, ! secondary metabolic process GO:0019748 59 58 1,000 5,386E-04 0,01240921 ! translation initiation factor activity GO:0003743 58 58 1,000 5,386E-04 0,01232966 ! multicellular organism reproduction GO:0032504 62 60 1,000 5,764E-04 0,01310995 GO:0048609|reproductive process in a multicellular organism, ! myeloid cell differentiation GO:0030099 64 60 1,000 5,764E-04 0,01302698 ! oxygen and reactive oxygen species metabolic process GO:0006800 60 60 1,000 5,764E-04 0,01294505 ! lung development GO:0030324 65 64 1,000 6,557E-04 0,01463347 ! response to metal ion GO:0010038 69 65 1,000 6,763E-04 0,01499949 ! positive regulation of protein modification process GO:0031401 69 65 1,000 6,763E-04 0,0149069 ! response to unfolded protein GO:0006986 68 66 1,000 6,972E-04 0,01527359 ! respiratory tube development GO:0030323 68 67 1,000 7,184E-04 0,01564259 ! mRNA transport GO:0051028 70 67 1,000 7,184E-04 0,01554778 ! regulation of caspase activity GO:0043281 70 67 1,000 7,184E-04 0,01545412 ! Ras GTPase binding GO:0017016 70 67 1,000 7,184E-04 0,01536158 ! respiratory system development GO:0060541 69 68 1,000 7,399E-04 0,01572789 ! regulation of endopeptidase activity GO:0052548 72 69 1,000 7,618E-04 0,01609643 ! eye development GO:0001654 74 69 1,000 7,618E-04 0,01600175 ! early endosome GO:0005769 79 70 1,000 7,839E-04 0,01637087 ! nuclear import GO:0051170 74 70 1,000 7,839E-04 0,01627569 ! response to inorganic substance GO:0010035 74 70 1,000 7,839E-04 0,01618161 ! female pregnancy GO:0007565 71 70 1,000 7,839E-04 0,01608861 ! FAD binding GO:0050660 72 71 1,000 8,064E-04 0,01645513 ! response to protein stimulus GO:0051789 74 72 1,000 8,292E-04 0,01682377 ! regulation of peptidase activity GO:0052547 78 74 1,000 8,757E-04 0,01766653 ! regulation of blood pressure GO:0008217 76 74 1,000 8,757E-04 0,01756728 ! small GTPase binding GO:0031267 78 75 1,000 8,994E-04 0,01794205 ! establishment of RNA localization GO:0051236 78 75 1,000 8,994E-04 0,01784237 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! phosphoinositide-mediated signaling GO:0048015 79 75 1,000 8,994E-04 0,0177438 ! cysteine-type endopeptidase activity GO:0004197 75 75 1,000 8,994E-04 0,0176463 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 76 76 1,000 9,234E-04 0,01801848 ! vitamin metabolic process GO:0006766 77 76 1,000 9,234E-04 0,01792056 ! RNA localization GO:0006403 80 77 1,000 9,477E-04 0,01829318 ! regulation of T cell activation GO:0050863 84 79 1,000 9,973E-04 0,01914653 ! regulation of DNA metabolic process GO:0051052 90 80 1,000 1,023E-03 0,01952626 ! GTPase binding GO:0051020 83 80 1,000 1,023E-03 0,0194224 ! protein kinase binding GO:0019901 89 80 1,000 1,023E-03 0,01931963 ! ossification GO:0001503 85 81 1,000 1,048E-03 0,01969823 ! interphase of mitotic cell cycle GO:0051329 84 82 1,000 1,074E-03 0,02007861 GO:0051325|interphase, ! bone development GO:0060348 86 82 1,000 1,074E-03 0,01997404 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 92 89 1,000 1,264E-03 0,02337865 ! nuclear membrane GO:0031965 92 90 1,000 1,292E-03 0,0237792 ! angiogenesis GO:0001525 95 92 1,000 1,349E-03 0,02471073 ! in utero embryonic development GO:0001701 97 95 1,000 1,438E-03 0,0261983 ! regulation of lymphocyte activation GO:0051249 100 95 1,000 1,438E-03 0,02606532 ! translation factor activity, nucleic acid binding GO:0008135 99 96 1,000 1,468E-03 0,02647705 ! cell fate commitment GO:0045165 98 96 1,000 1,468E-03 0,026344 ! protein C-terminus binding GO:0008022 106 99 1,000 1,56E-03 0,02785852 ! kinase binding GO:0019900 108 99 1,000 1,56E-03 0,02771992 ! electron transport chain GO:0022900 102 100 1,000 1,592E-03 0,02813668 ! cytokine binding GO:0019955 101 100 1,000 1,592E-03 0,02799808 ! tRNA transcription GO:0009304 5 5 0,000 3,051E-03 0,05340475 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 5 5 0,000 3,051E-03 0,05314424 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 3,051E-03 0,05288625 ! benzene and derivative metabolic process GO:0042537 5 5 0,000 3,051E-03 0,05263076 ! response to oxygen radical GO:0000305 5 5 0,000 3,051E-03 0,05237773 ! positive regulation of axon extension GO:0045773 6 5 0,000 3,051E-03 0,05212712 ! negative regulation of bone resorption GO:0045779 5 5 0,000 3,051E-03 0,0518789 ! positive regulation of lipid biosynthetic process GO:0046889 5 5 0,000 3,051E-03 0,05163302 ! regulation of interferon-beta production GO:0032648 6 5 0,000 3,051E-03 0,05138947 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! sodium-independent organic anion transmembrane transporter activity GO:0015347 6 5 0,000 3,051E-03 0,05114821 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 3,051E-03 0,0509092 ! negative regulation of transmembrane transport GO:0034763 5 5 0,000 3,051E-03 0,05067241 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! hypothalamus development GO:0021854 5 5 0,000 3,051E-03 0,05043782 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 3,051E-03 0,05020538 ! N-terminal protein lipidation GO:0006498 5 5 0,000 3,051E-03 0,04997508 ! glycolipid transport GO:0046836 5 5 0,000 3,051E-03 0,04974689 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 5 5 0,000 3,051E-03 0,04952076 ! phosphoinositide 3-kinase binding GO:0043548 5 5 0,000 3,051E-03 0,04929669 ! protein amino acid sulfation GO:0006477 5 5 0,000 3,051E-03 0,04907463 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 6 5 0,000 3,051E-03 0,04885457 ! opioid peptide activity GO:0001515 5 5 0,000 3,051E-03 0,04863647 ! selenocysteine incorporation GO:0001514 5 5 0,000 3,051E-03 0,0484203 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 5 5 0,000 3,051E-03 0,04820605 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 5 5 0,000 3,051E-03 0,04799369 ! elastic fiber assembly GO:0048251 5 5 0,000 3,051E-03 0,04778319 ! regulation of mitochondrial membrane permeability GO:0046902 5 5 0,000 3,051E-03 0,04757453 ! neurofilament cytoskeleton organization GO:0060052 5 5 0,000 3,051E-03 0,04736769 ! ruffle membrane GO:0032587 5 5 0,000 3,051E-03 0,04716263 ! regulation of histone modification GO:0031056 5 5 0,000 3,051E-03 0,04695935 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 3,051E-03 0,0467578 ! behavioral response to pain GO:0048266 5 5 0,000 3,051E-03 0,04655798 ! clathrin coat assembly GO:0048268 6 5 0,000 3,051E-03 0,04635986 ! Notch receptor processing GO:0007220 5 5 0,000 3,051E-03 0,04616342 ! cerebral cortex radially oriented cell migration GO:0021799 5 5 0,000 3,051E-03 0,04596864 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 6 5 0,000 3,051E-03 0,0457755 ! serotonin receptor signaling pathway GO:0007210 5 5 0,000 3,051E-03 0,04558397 ! oxidoreductase activity, oxidizing metal ions GO:0016722 5 5 0,000 3,051E-03 0,04539403 ! response to lipid GO:0033993 5 5 0,000 3,051E-03 0,04520568 ! cytoplasmic dynein complex GO:0005868 6 5 0,000 3,051E-03 0,04501888 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 3,051E-03 0,04483361 ! positive regulation of muscle cell differentiation GO:0051149 5 5 0,000 3,051E-03 0,04464987 ! smooth muscle cell differentiation GO:0051145 5 5 0,000 3,051E-03 0,04446763 ! exo-alpha-sialidase activity GO:0004308 5 5 0,000 3,051E-03 0,04428686 GO:0016997|alpha-sialidase activity, ! regulation of odontogenesis GO:0042481 5 5 0,000 3,051E-03 0,04410756 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 3,051E-03 0,04392971 ! formate-tetrahydrofolate ligase activity GO:0004329 5 5 0,000 3,051E-03 0,04375329 ! negative regulation of heart contraction GO:0045822 5 5 0,000 3,051E-03 0,04357827 ! ovulation from ovarian follicle GO:0001542 5 5 0,000 3,051E-03 0,04340465 ! DNA ligation during DNA repair GO:0051103 5 5 0,000 3,051E-03 0,04323241 ! 1-acylglycerophosphocholine O-acyltransferase activity GO:0047184 5 5 0,000 3,051E-03 0,04306153 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 3,051E-03 0,042892 ! negative regulation of endocytosis GO:0045806 5 5 0,000 3,051E-03 0,0427238 ! microfibril GO:0001527 5 5 0,000 3,051E-03 0,04255691 GO:0043205|fibril, ! parathyroid gland development GO:0060017 5 5 0,000 3,051E-03 0,04239132 ! toxin metabolic process GO:0009404 5 5 0,000 3,051E-03 0,04222701 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 3,051E-03 0,04206397 ! cytokine secretion GO:0050663 5 5 0,000 3,051E-03 0,04190219 ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 5 5 0,000 3,051E-03 0,04174164 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 3,051E-03 0,04158232 ! skeletal myofibril assembly GO:0014866 5 5 0,000 3,051E-03 0,04142421 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 5 0,000 3,051E-03 0,0412673 ! epithelial cell proliferation GO:0050673 5 5 0,000 3,051E-03 0,04111158 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 5 5 0,000 3,051E-03 0,04095702 ! regulation of retroviral genome replication GO:0045091 5 5 0,000 3,051E-03 0,04080363 ! negative regulation of survival gene product expression GO:0008634 5 5 0,000 3,051E-03 0,04065137 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 3,051E-03 0,04050025 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of defense response to virus by host GO:0050691 5 5 0,000 3,051E-03 0,04035025 ! transmembrane-ephrin receptor activity GO:0005005 5 5 0,000 3,051E-03 0,04020136 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 3,051E-03 0,04005356 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 3,051E-03 0,03990684 ! glutamate catabolic process GO:0006538 6 5 0,000 3,051E-03 0,0397612 ! positive regulation of isotype switching to IgG isotypes GO:0048304 9 5 0,000 3,051E-03 0,03961661 ! microvillus organization GO:0032528 5 5 0,000 3,051E-03 0,03947307 GO:0030033|microvillus assembly, ! tyrosine catabolic process GO:0006572 5 5 0,000 3,051E-03 0,03933057 ! L-serine biosynthetic process GO:0006564 5 5 0,000 3,051E-03 0,03918909 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 3,051E-03 0,03904863 ! pericentriolar material GO:0000242 6 5 0,000 3,051E-03 0,03890917 ! polyol biosynthetic process GO:0046173 5 5 0,000 3,051E-03 0,03877071 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 6 5 0,000 3,051E-03 0,03863322 ! platelet-derived growth factor alpha-receptor activity GO:0005018 5 5 0,000 3,051E-03 0,03849671 ! proton-transporting V-type ATPase, V0 domain GO:0033179 5 5 0,000 3,051E-03 0,03836116 ! fibroblast growth factor receptor activity GO:0005007 5 5 0,000 3,051E-03 0,03822656 ! protein-DNA loading ATPase activity GO:0033170 5 5 0,000 3,051E-03 0,0380929 GO:0003689|DNA clamp loader activity, ! insulin-like growth factor receptor activity GO:0005010 5 5 0,000 3,051E-03 0,03796017 ! response to tumor necrosis factor GO:0034612 6 5 0,000 3,051E-03 0,03782836 ! mRNA transcription GO:0009299 6 5 0,000 3,051E-03 0,03769747 ! response to ATP GO:0033198 5 5 0,000 3,051E-03 0,03756748 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 5 5 0,000 3,051E-03 0,03743838 ! adenosine receptor activity, G-protein coupled GO:0001609 5 5 0,000 3,051E-03 0,03731017 ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 3,051E-03 0,03718283 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 5 5 0,000 3,051E-03 0,03705635 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 3,051E-03 0,03693074 ! multivesicular body GO:0005771 5 5 0,000 3,051E-03 0,03680597 ! positive regulation of transporter activity GO:0032411 5 5 0,000 3,051E-03 0,03668205 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 5 5 0,000 3,051E-03 0,03655895 ! forebrain neuron development GO:0021884 6 5 0,000 3,051E-03 0,03643668 ! insulin-like growth factor I binding GO:0031994 5 5 0,000 3,051E-03 0,03631523 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 5 5 0,000 3,051E-03 0,03619458 ! demethylase activity GO:0032451 5 5 0,000 3,051E-03 0,03607473 ! peptidyl-histidine phosphorylation GO:0018106 5 5 0,000 3,051E-03 0,03595567 ! epithelial cell maturation GO:0002070 5 5 0,000 3,051E-03 0,0358374 ! nitric-oxide synthase regulator activity GO:0030235 5 5 0,000 3,051E-03 0,0357199 ! regulation of immunoglobulin secretion GO:0051023 5 5 0,000 3,051E-03 0,03560316 ! zymogen granule GO:0042588 5 5 0,000 3,051E-03 0,03548719 ! guanylate cyclase regulator activity GO:0030249 5 5 0,000 3,051E-03 0,03537197 GO:0010851|cyclase regulator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 3,051E-03 0,0352575 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! cellular glucose homeostasis GO:0001678 5 5 0,000 3,051E-03 0,03514377 ! early endosome to late endosome transport GO:0045022 5 5 0,000 3,051E-03 0,03503077 ! positive regulation of translational initiation GO:0045948 5 5 0,000 3,051E-03 0,03491849 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 3,051E-03 0,03480693 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 3,051E-03 0,03469608 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! semaphorin receptor activity GO:0017154 6 5 0,000 3,051E-03 0,03458593 ! proteoglycan binding GO:0043394 9 5 0,000 3,051E-03 0,03447648 ! regulation of collagen metabolic process GO:0010712 6 5 0,000 3,051E-03 0,03436772 ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 6 5 0,000 3,051E-03 0,03425965 ! zinc ion homeostasis GO:0055069 5 5 0,000 3,051E-03 0,03415225 GO:0006882|cellular zinc ion homeostasis, ! deoxyribonucleoside metabolic process GO:0009120 6 5 0,000 3,051E-03 0,03404553 ! nucleoside monophosphate catabolic process GO:0009125 5 5 0,000 3,051E-03 0,03393946 ! activated T cell proliferation GO:0050798 6 5 0,000 3,051E-03 0,03383406 ! advanced glycation end-product receptor activity GO:0050785 5 5 0,000 3,051E-03 0,03372931 ! dynein binding GO:0045502 5 5 0,000 3,051E-03 0,03362521 ! regulation of dendrite development GO:0050773 5 5 0,000 3,051E-03 0,03352175 ! cardiac muscle cell development GO:0055013 5 5 0,000 3,051E-03 0,03341892 ! anterograde axon cargo transport GO:0008089 5 5 0,000 3,051E-03 0,03331672 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 3,051E-03 0,03321515 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 3,051E-03 0,03311419 GO:0003923|GPI-anchor transamidase activity, ! lymphoid progenitor cell differentiation GO:0002320 5 5 0,000 3,051E-03 0,03301384 ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 3,051E-03 0,0329141 ! sphingomyelin catabolic process GO:0006685 6 5 0,000 3,051E-03 0,03281496 ! high-density lipoprotein binding GO:0008035 5 5 0,000 3,051E-03 0,03271642 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 3,051E-03 0,03261847 ! positive regulation of B cell differentiation GO:0045579 5 5 0,000 3,051E-03 0,0325211 ! regulation of acetylcholine secretion GO:0014056 5 5 0,000 3,051E-03 0,03242431 ! centromeric DNA binding GO:0019237 5 5 0,000 3,051E-03 0,0323281 ! cyclohydrolase activity GO:0019238 5 5 0,000 3,051E-03 0,03223245 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 3,051E-03 0,03213737 ! positive T cell selection GO:0043368 9 5 0,000 3,051E-03 0,03204285 ! neural tube patterning GO:0021532 5 5 0,000 3,051E-03 0,03194888 ! amylase activity GO:0016160 5 5 0,000 3,051E-03 0,03185546 ! metaphase plate congression GO:0051310 5 5 0,000 3,051E-03 0,03176259 ! regulation of sterol transport GO:0032371 5 5 0,000 3,051E-03 0,03167026 GO:0032374|regulation of cholesterol transport, ! sympathetic nervous system development GO:0048485 5 5 0,000 3,051E-03 0,03157846 ! oxygen homeostasis GO:0032364 5 5 0,000 3,051E-03 0,03148719 ! skeletal muscle regeneration GO:0043403 5 5 0,000 3,051E-03 0,03139645 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 5 5 0,000 3,051E-03 0,03130623 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 5 5 0,000 3,051E-03 0,03121653 ! SAP kinase activity GO:0016909 5 5 0,000 3,051E-03 0,03112734 ! positive regulation of pseudopodium assembly GO:0031274 5 5 0,000 3,051E-03 0,03103866 GO:0031272|regulation of pseudopodium assembly, ! phosphatidylserine binding GO:0001786 5 5 0,000 3,051E-03 0,03095048 ! alpha-mannosidase activity GO:0004559 6 5 0,000 3,051E-03 0,0308628 ! alpha-glucosidase activity GO:0004558 6 5 0,000 3,051E-03 0,03077562 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 3,051E-03 0,03068892 ! myeloid dendritic cell activation GO:0001773 5 5 0,000 3,051E-03 0,03060272 GO:0043011|myeloid dendritic cell differentiation, ! anaphase GO:0051322 5 5 0,000 3,051E-03 0,030517 GO:0000090|mitotic anaphase, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 3,051E-03 0,03043175 ! ribonuclease H activity GO:0004523 5 5 0,000 3,051E-03 0,03034699 ! CARD domain binding GO:0050700 5 5 0,000 3,051E-03 0,03026269 ! regulation of muscle cell apoptosis GO:0010660 5 5 0,000 3,051E-03 0,03017886 ! AP-2 adaptor complex GO:0030122 5 5 0,000 3,051E-03 0,03009549 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 5 5 0,000 3,051E-03 0,03001258 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 3,051E-03 0,02993013 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 3,051E-03 0,02984813 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 3,051E-03 0,02976658 ! negative regulation of macrophage differentiation GO:0045650 5 5 0,000 3,051E-03 0,02968547 ! negative regulation of osteoclast differentiation GO:0045671 5 5 0,000 3,051E-03 0,02960481 ! ceramidase activity GO:0017040 5 5 0,000 3,051E-03 0,02952458 ! negative regulation of osteoblast differentiation GO:0045668 6 5 0,000 3,051E-03 0,02944478 ! GTP-Rho binding GO:0017049 5 5 0,000 3,051E-03 0,02936541 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 3,051E-03 0,02928647 ! chondroitin sulfotransferase activity GO:0034481 5 5 0,000 3,051E-03 0,02920796 ! positive regulation of T-helper 2 cell differentiation GO:0045630 5 5 0,000 3,051E-03 0,02912986 ! alcohol transmembrane transporter activity GO:0015665 5 5 0,000 3,051E-03 0,02905218 GO:0015166|polyol transmembrane transporter activity, ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 3,051E-03 0,02897492 ! TAP complex GO:0042825 5 5 0,000 3,051E-03 0,02889806 ! bHLH transcription factor binding GO:0043425 5 5 0,000 3,051E-03 0,02882161 ! actinin binding GO:0042805 6 5 0,000 3,051E-03 0,02874556 ! secretory granule organization GO:0033363 5 5 0,000 3,051E-03 0,02866992 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 5 5 0,000 3,051E-03 0,02859467 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 3,051E-03 0,02851981 ! striatum development GO:0021756 5 5 0,000 3,051E-03 0,02844535 ! photoreceptor inner segment GO:0001917 5 5 0,000 3,051E-03 0,02837127 ! regulation of T cell mediated cytotoxicity GO:0001914 9 5 0,000 3,051E-03 0,02829758 ! aldehyde-lyase activity GO:0016832 5 5 0,000 3,051E-03 0,02822427 ! regulation of mitochondrial depolarization GO:0051900 5 5 0,000 3,051E-03 0,02815134 ! T cell activation during immune response GO:0002286 5 5 0,000 3,051E-03 0,02807878 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 3,051E-03 0,0280066 ! 1-aminocyclopropane-1-carboxylate synthase activity GO:0016847 5 5 0,000 3,051E-03 0,02793479 ! dystroglycan complex GO:0016011 6 5 0,000 3,051E-03 0,02786335 ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 5 5 0,000 3,051E-03 0,02779227 ! neural plate development GO:0001840 5 5 0,000 3,051E-03 0,02772155 ! toll-like receptor signaling pathway GO:0002224 5 5 0,000 3,051E-03 0,02765119 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 3,051E-03 0,02758119 ! phosphopantetheine binding GO:0031177 5 5 0,000 3,051E-03 0,02751154 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 3,051E-03 0,02744224 ! negative regulation of actin filament bundle formation GO:0032232 8 5 0,000 3,051E-03 0,02737329 GO:0051497|negative regulation of stress fiber formation, ! organ or tissue specific immune response GO:0002251 5 5 0,000 3,051E-03 0,02730468 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 3,051E-03 0,02723642 ! diacylglycerol metabolic process GO:0046339 5 5 0,000 3,051E-03 0,0271685 ! cytoplasmic microtubule organization GO:0031122 5 5 0,000 3,051E-03 0,02710092 ! retina homeostasis GO:0001895 5 5 0,000 3,051E-03 0,02703367 ! release of sequestered calcium ion into cytosol GO:0051209 10 5 0,000 3,051E-03 0,02696675 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 5 5 0,000 3,051E-03 0,02690017 ! regulation of growth hormone secretion GO:0060123 6 5 0,000 3,051E-03 0,02683391 ! collagen type IV GO:0005587 5 5 0,000 3,051E-03 0,02676798 ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 3,051E-03 0,02670237 ! testosterone 17-beta-dehydrogenase (NADP+) activity GO:0047045 5 5 0,000 3,051E-03 0,02663709 ! retrograde protein transport, ER to cytosol GO:0030970 5 5 0,000 3,051E-03 0,02657212 ! spindle assembly GO:0051225 5 5 0,000 3,051E-03 0,02650747 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 3,051E-03 0,02644313 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 5 5 0,000 3,051E-03 0,0263791 GO:0022011|myelination in the peripheral nervous system, ! drug metabolic process GO:0017144 5 5 0,000 3,051E-03 0,02631538 ! protein amino acid prenylation GO:0018346 5 5 0,000 3,051E-03 0,02625197 ! stem cell division GO:0017145 5 5 0,000 3,051E-03 0,02618887 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 3,051E-03 0,02612606 ! phospholipid scrambling GO:0017121 5 5 0,000 3,051E-03 0,02606356 GO:0017128|phospholipid scramblase activity, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 5 5 0,000 3,051E-03 0,02600136 ! regulation of humoral immune response GO:0002920 9 5 0,000 3,051E-03 0,02593945 ! H3/H4 histone acetyltransferase activity GO:0004406 5 5 0,000 3,051E-03 0,02587783 ! regulation of interferon-alpha biosynthetic process GO:0045354 6 5 0,000 3,051E-03 0,02581651 ! negative regulation of protein ubiquitination GO:0031397 5 5 0,000 3,051E-03 0,02575548 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 3,051E-03 0,02569474 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of cAMP biosynthetic process GO:0030819 5 5 0,000 3,051E-03 0,02563428 GO:0030816|positive regulation of cAMP metabolic process, ! phagocytic vesicle GO:0045335 5 5 0,000 3,051E-03 0,0255741 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 3,051E-03 0,02551421 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 3,051E-03 0,0254546 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 3,051E-03 0,02539526 ! polyol transport GO:0015791 6 5 0,000 3,051E-03 0,02533621 ! cell adhesion mediated by integrin GO:0033627 6 5 0,000 3,051E-03 0,02527742 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 3,051E-03 0,02521891 ! glycerol-3-phosphate metabolic process GO:0006072 5 5 0,000 3,051E-03 0,02516067 ! platelet activating factor metabolic process GO:0046469 5 5 0,000 3,051E-03 0,02510269 ! cobalt ion transport GO:0006824 5 5 0,000 3,051E-03 0,02504498 ! response to zinc ion GO:0010043 5 5 0,000 3,051E-03 0,02498754 ! poly(U) RNA binding GO:0008266 5 5 0,000 3,051E-03 0,02493036 ! negative regulation of cell-cell adhesion GO:0022408 5 5 0,000 3,051E-03 0,02487344 ! adaptation of signaling pathway GO:0022401 5 5 0,000 3,051E-03 0,02481678 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! glucocorticoid receptor signaling pathway GO:0042921 5 5 0,000 3,051E-03 0,02476038 GO:0031958|corticosteroid receptor signaling pathway, ! regulation of gluconeogenesis GO:0006111 5 5 0,000 3,051E-03 0,02470424 ! sensory perception of bitter taste GO:0050913 5 5 0,000 3,051E-03 0,02464834 ! regulation of dopamine uptake GO:0051584 5 5 0,000 3,051E-03 0,0245927 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! opsonization GO:0008228 5 5 0,000 3,051E-03 0,02453732 ! protein maturation by protein folding GO:0022417 5 5 0,000 3,051E-03 0,02448218 ! neuron remodeling GO:0016322 6 5 0,000 3,051E-03 0,02442728 ! neurexin binding GO:0042043 5 5 0,000 3,051E-03 0,02437264 ! sensory perception of temperature stimulus GO:0050951 5 5 0,000 3,051E-03 0,02431823 ! regulation of potassium ion transport GO:0043266 5 5 0,000 3,051E-03 0,02426407 ! low-density lipoprotein particle GO:0034362 5 5 0,000 3,051E-03 0,02421015 ! chemoattractant activity GO:0042056 5 5 0,000 3,051E-03 0,02415647 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 6 5 0,000 3,051E-03 0,02410303 ! lipoic acid binding GO:0031405 5 5 0,000 3,051E-03 0,02404982 ! lithium ion binding GO:0031403 6 5 0,000 3,051E-03 0,02399685 ! lipoprotein particle clearance GO:0034381 5 5 0,000 3,051E-03 0,02394411 ! grooming behavior GO:0007625 5 5 0,000 3,051E-03 0,0238916 ! sequestering of actin monomers GO:0042989 5 5 0,000 3,051E-03 0,02383932 ! cobalamin binding GO:0031419 5 5 0,000 3,051E-03 0,02378727 ! retinoic acid binding GO:0001972 5 5 0,000 3,051E-03 0,02373544 ! response to axon injury GO:0048678 5 5 0,000 3,051E-03 0,02368384 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 3,051E-03 0,02363247 ! regulation of activin receptor signaling pathway GO:0032925 5 5 0,000 3,051E-03 0,02358132 ! positive regulation of neurotransmitter secretion GO:0001956 5 5 0,000 3,051E-03 0,02353038 ! mitochondrial genome maintenance GO:0000002 5 5 0,000 3,051E-03 0,02347967 ! protein-lysine 6-oxidase activity GO:0004720 6 5 0,000 3,051E-03 0,02342918 ! female pronucleus GO:0001939 5 5 0,000 3,051E-03 0,0233789 ! F-actin capping protein complex GO:0008290 5 5 0,000 3,051E-03 0,02332884 ! DNA topoisomerase activity GO:0003916 5 5 0,000 3,051E-03 0,02327899 ! poly(ADP-ribose) glycohydrolase activity GO:0004649 6 5 0,000 3,051E-03 0,02322936 ! spinal cord dorsal/ventral patterning GO:0021513 5 5 0,000 3,051E-03 0,02317993 ! dorsal spinal cord development GO:0021516 5 5 0,000 3,051E-03 0,02313072 ! ceramide catabolic process GO:0046514 5 5 0,000 3,051E-03 0,02308171 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 3,051E-03 0,02303291 ! neutrophil mediated immunity GO:0002446 5 5 0,000 3,051E-03 0,02298432 ! regulation of oligodendrocyte differentiation GO:0048713 5 5 0,000 3,051E-03 0,02293593 ! Rap GTPase activator activity GO:0046582 5 5 0,000 3,051E-03 0,02288775 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 6 5 0,000 3,051E-03 0,02283977 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 5 5 0,000 3,051E-03 0,02279198 ! positive regulation of filopodium assembly GO:0051491 5 5 0,000 3,051E-03 0,0227444 GO:0051489|regulation of filopodium assembly, ! heart trabecula formation GO:0060347 5 5 0,000 3,051E-03 0,02269702 GO:0060343|trabecula formation, ! amine oxidase activity GO:0008131 6 5 0,000 3,051E-03 0,02264983 ! neutrophil activation GO:0042119 5 5 0,000 3,051E-03 0,02260284 ! regulation of response to food GO:0032095 5 5 0,000 3,051E-03 0,02255604 ! response to food GO:0032094 5 5 0,000 3,051E-03 0,02250944 ! hedgehog receptor activity GO:0008158 5 5 0,000 3,051E-03 0,02246303 ! protein phosphatase 1 binding GO:0008157 5 5 0,000 3,051E-03 0,02241681 ! lipoprotein catabolic process GO:0042159 5 5 0,000 3,051E-03 0,02237078 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 3,051E-03 0,02232493 ! organ growth GO:0035265 7 5 0,000 3,051E-03 0,02227928 ! positive regulation of multicellular organismal metabolic process GO:0044253 6 5 0,000 3,051E-03 0,02223381 ! small-subunit processome GO:0032040 5 5 0,000 3,051E-03 0,02218853 ! UDP-glucosyltransferase activity GO:0035251 5 5 0,000 3,051E-03 0,02214343 ! myosin heavy chain binding GO:0032036 5 5 0,000 3,051E-03 0,02209852 ! nucleoside salvage GO:0043174 7 5 0,000 3,051E-03 0,02205378 GO:0006166|purine ribonucleoside salvage, ! nucleobase transport GO:0015851 5 5 0,000 3,051E-03 0,02200923 ! GPI anchor binding GO:0034235 6 5 0,000 3,051E-03 0,02196486 ! thrombin receptor activity GO:0015057 5 5 0,000 3,051E-03 0,02192066 ! nucleotide-excision repair complex GO:0000109 6 5 0,000 3,051E-03 0,02187664 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 5 5 0,000 3,051E-03 0,0218328 ! dendritic shaft GO:0043198 5 5 0,000 3,051E-03 0,02178914 ! terminal button GO:0043195 8 5 0,000 3,051E-03 0,02174565 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 3,051E-03 0,02170233 GO:0016274|protein-arginine N-methyltransferase activity, ! ferrous iron binding GO:0008198 6 5 0,000 3,051E-03 0,02165918 ! eukaryotic initiation factor 4E binding GO:0008190 5 5 0,000 3,051E-03 0,02161621 ! G2/M transition checkpoint GO:0031576 5 5 0,000 3,051E-03 0,0215734 GO:0031572|G2/M transition DNA damage checkpoint, ! negative regulation of peptide secretion GO:0002792 6 5 0,000 3,051E-03 0,02153077 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 5 5 0,000 3,051E-03 0,0214883 ! response to UV-C GO:0010225 5 5 0,000 3,051E-03 0,021446 ! carbonyl reductase (NADPH) activity GO:0004090 5 5 0,000 3,051E-03 0,02140387 ! regulation of alpha-beta T cell proliferation GO:0046640 9 5 0,000 3,051E-03 0,0213619 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! positive regulation of organ growth GO:0046622 5 5 0,000 3,051E-03 0,02132009 ! 1-alkyl-2-acetylglycerophosphocholine esterase activity GO:0003847 5 5 0,000 3,051E-03 0,02127845 ! IgE binding GO:0019863 5 5 0,000 3,051E-03 0,02123698 ! 3-beta-hydroxy-delta5-steroid dehydrogenase activity GO:0003854 5 5 0,000 3,051E-03 0,02119566 ! monoamine transmembrane transporter activity GO:0008504 5 5 0,000 3,051E-03 0,0211545 ! response to cadmium ion GO:0046686 5 5 0,000 3,051E-03 0,0211135 ! regulation of interleukin-4 production GO:0032673 5 5 0,000 3,051E-03 0,02107267 ! hair follicle maturation GO:0048820 5 5 0,000 3,051E-03 0,02103199 ! regulation of interleukin-10 production GO:0032653 5 5 0,000 3,051E-03 0,02099146 ! ribosomal large subunit biogenesis GO:0042273 5 5 0,000 3,051E-03 0,02095109 ! base conversion or substitution editing GO:0016553 5 5 0,000 3,051E-03 0,02091088 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 3,051E-03 0,02087082 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 3,051E-03 0,02083091 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 3,051E-03 0,02079116 GO:0005218|intracellular ligand-gated calcium channel activity, ! general transcriptional repressor activity GO:0016565 5 5 0,000 3,051E-03 0,02075156 ! peroxisome fission GO:0016559 5 5 0,000 3,051E-03 0,02071211 ! alpha-tubulin binding GO:0043014 5 5 0,000 3,051E-03 0,02067281 ! mitotic recombination GO:0006312 5 5 0,000 3,051E-03 0,02063365 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 3,051E-03 0,02059465 ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 3,051E-03 0,02055579 ! positive regulation of chemokine production GO:0032722 5 5 0,000 3,051E-03 0,02051708 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 3,051E-03 0,02047851 ! muscle cell proliferation GO:0033002 5 5 0,000 3,051E-03 0,02044009 ! membrane to membrane docking GO:0022614 5 5 0,000 3,051E-03 0,02040181 ! translation activator activity GO:0008494 5 5 0,000 3,051E-03 0,02036368 ! N-formyl peptide receptor activity GO:0004982 5 5 0,000 3,051E-03 0,02032569 ! coenzyme A biosynthetic process GO:0015937 6 5 0,000 3,051E-03 0,02028784 ! histamine receptor activity GO:0004969 5 5 0,000 3,051E-03 0,02025013 ! dopamine receptor activity GO:0004952 5 5 0,000 3,051E-03 0,02021256 ! galactosidase activity GO:0015925 5 5 0,000 3,051E-03 0,02017513 ! prostaglandin E receptor activity GO:0004957 6 5 0,000 3,051E-03 0,02013783 ! cellular response to nutrient GO:0031670 5 5 0,000 3,051E-03 0,02010068 ! basic amino acid transmembrane transporter activity GO:0015174 5 5 0,000 3,051E-03 0,02006366 ! ATP-gated cation channel activity GO:0004931 7 5 0,000 3,051E-03 0,02002678 ! cytochrome-b5 reductase activity GO:0004128 5 5 0,000 3,051E-03 0,01999003 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 3,051E-03 0,01995342 ! glycine transmembrane transporter activity GO:0015187 5 5 0,000 3,051E-03 0,01991694 ! tyrosine phosphorylation of STAT protein GO:0007260 6 5 0,000 3,051E-03 0,0198806 ! tricarboxylic acid cycle enzyme complex GO:0045239 5 5 0,000 3,051E-03 0,01984439 ! RNA polymerase I transcription factor activity GO:0003701 5 5 0,000 3,051E-03 0,01980831 ! progesterone metabolic process GO:0042448 5 5 0,000 3,051E-03 0,01977236 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 5 5 0,000 3,051E-03 0,01973654 ! disaccharide metabolic process GO:0005984 5 5 0,000 3,051E-03 0,01970085 ! 5'-3' exonuclease activity GO:0008409 5 5 0,000 3,051E-03 0,01966529 ! type II transforming growth factor beta receptor binding GO:0005114 5 5 0,000 3,051E-03 0,01962985 ! histone acetyltransferase binding GO:0035035 5 5 0,000 3,051E-03 0,01959455 ! endosome to lysosome transport GO:0008333 5 5 0,000 3,051E-03 0,01955937 ! glial cell migration GO:0008347 5 5 0,000 3,051E-03 0,01952432 ! S-acyltransferase activity GO:0016417 5 5 0,000 3,051E-03 0,01948939 ! phosphoinositide 3-kinase regulator activity GO:0035014 5 5 0,000 3,051E-03 0,01945459 ! phosphatidylinositol-4-phosphate 3-kinase activity GO:0035005 5 5 0,000 3,051E-03 0,01941991 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 3,051E-03 0,01938535 ! nucleobase transmembrane transporter activity GO:0015205 5 5 0,000 3,051E-03 0,01935092 ! asparaginase activity GO:0004067 5 5 0,000 3,051E-03 0,01931661 ! insemination GO:0007320 5 5 0,000 3,051E-03 0,01928242 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 3,051E-03 0,01924835 ! negative regulation of smooth muscle contraction GO:0045986 6 5 0,000 3,051E-03 0,01921441 ! aminoacylase activity GO:0004046 5 5 0,000 3,051E-03 0,01918058 ! receptor biosynthetic process GO:0032800 5 5 0,000 3,051E-03 0,01914687 ! penetration of zona pellucida GO:0007341 5 5 0,000 3,051E-03 0,01911328 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 6 5 0,000 3,051E-03 0,0190798 ! aldehyde reductase activity GO:0004032 5 5 0,000 3,051E-03 0,01904645 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 5 0,000 3,051E-03 0,01901321 ! unconventional myosin complex GO:0016461 5 5 0,000 3,051E-03 0,01898008 ! carnitine metabolic process GO:0009437 5 5 0,000 3,051E-03 0,01894708 GO:0006577|betaine metabolic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 6 6 0,000 3,66E-03 0,02269086 ! regulation of helicase activity GO:0051095 6 6 0,000 3,66E-03 0,02265153 ! testosterone 17-beta-dehydrogenase activity GO:0050327 6 6 0,000 3,66E-03 0,02261234 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 6 6 0,000 3,66E-03 0,02257329 ! tumor necrosis factor-mediated signaling pathway GO:0033209 6 6 0,000 3,66E-03 0,02253437 ! negative regulation of small GTPase mediated signal transduction GO:0051058 7 6 0,000 3,66E-03 0,02249558 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 7 6 0,000 3,66E-03 0,02245693 ! regulation of hormone biosynthetic process GO:0046885 6 6 0,000 3,66E-03 0,02241841 ! ephrin receptor binding GO:0046875 7 6 0,000 3,66E-03 0,02238002 ! biotin binding GO:0009374 7 6 0,000 3,66E-03 0,02234177 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 3,66E-03 0,02230364 ! insulin receptor substrate binding GO:0043560 7 6 0,000 3,66E-03 0,02226564 ! drug:hydrogen antiporter activity GO:0015307 6 6 0,000 3,66E-03 0,02222778 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 3,66E-03 0,02219004 ! carbohydrate phosphorylation GO:0046835 6 6 0,000 3,66E-03 0,02215243 ! regulation of respiratory gaseous exchange GO:0043576 6 6 0,000 3,66E-03 0,02211495 ! neuron adhesion GO:0007158 6 6 0,000 3,66E-03 0,02207759 ! establishment of tissue polarity GO:0007164 7 6 0,000 3,66E-03 0,02204036 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 6 6 0,000 3,66E-03 0,02200325 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 3,66E-03 0,02196627 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 6 0,000 3,66E-03 0,02192942 ! regulation of cardiac muscle cell proliferation GO:0060043 6 6 0,000 3,66E-03 0,02189269 ! positive regulation of receptor-mediated endocytosis GO:0048260 6 6 0,000 3,66E-03 0,02185608 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 6 6 0,000 3,66E-03 0,02181959 ! eukaryotic translation elongation factor 1 complex GO:0005853 6 6 0,000 3,66E-03 0,02178322 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 3,66E-03 0,02174698 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 6 6 0,000 3,66E-03 0,02171085 ! cytoplasmic microtubule GO:0005881 7 6 0,000 3,66E-03 0,02167485 ! Arp2/3 protein complex GO:0005885 7 6 0,000 3,66E-03 0,02163896 ! neurofilament GO:0005883 6 6 0,000 3,66E-03 0,0216032 ! glial cell fate commitment GO:0021781 6 6 0,000 3,66E-03 0,02156755 ! dynactin complex GO:0005869 6 6 0,000 3,66E-03 0,02153201 ! fibroblast growth factor receptor antagonist activity GO:0030353 6 6 0,000 3,66E-03 0,0214966 GO:0005104|fibroblast growth factor receptor binding, GO:0005152|interleukin-1 receptor antagonist activity, ! translation repressor activity GO:0030371 6 6 0,000 3,66E-03 0,0214613 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 6 6 0,000 3,66E-03 0,02142612 ! lipopolysaccharide binding GO:0001530 6 6 0,000 3,66E-03 0,02139105 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 3,66E-03 0,0213561 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 3,66E-03 0,02132126 ! negative regulation of viral genome replication GO:0045071 6 6 0,000 3,66E-03 0,02128654 ! traversing start control point of mitotic cell cycle GO:0007089 6 6 0,000 3,66E-03 0,02125192 ! protein lipoylation GO:0009249 6 6 0,000 3,66E-03 0,02121742 ! cysteine metabolic process GO:0006534 6 6 0,000 3,66E-03 0,02118304 ! regulation of isotype switching to IgG isotypes GO:0048302 10 6 0,000 3,66E-03 0,02114876 ! histidine catabolic process GO:0006548 6 6 0,000 3,66E-03 0,02111459 GO:0009077|histidine family amino acid catabolic process, ! centromeric heterochromatin GO:0005721 6 6 0,000 3,66E-03 0,02108054 ! mitochondrial respiratory chain complex assembly GO:0033108 6 6 0,000 3,66E-03 0,02104659 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 6 6 0,000 3,66E-03 0,02101275 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 6 6 0,000 3,66E-03 0,02097903 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 6 6 0,000 3,66E-03 0,02094541 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 6 0,000 3,66E-03 0,02091189 ! microtubule nucleation GO:0007020 6 6 0,000 3,66E-03 0,02087849 ! proline biosynthetic process GO:0006561 7 6 0,000 3,66E-03 0,02084519 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 3,66E-03 0,020812 ! transforming growth factor beta receptor activity, type I GO:0005025 6 6 0,000 3,66E-03 0,02077891 ! phasic smooth muscle contraction GO:0014821 6 6 0,000 3,66E-03 0,02074593 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 3,66E-03 0,02071305 ! peptidoglycan metabolic process GO:0000270 6 6 0,000 3,66E-03 0,02068027 GO:0009253|peptidoglycan catabolic process, ! cerebral cortex neuron differentiation GO:0021895 6 6 0,000 3,66E-03 0,0206476 ! paraxial mesoderm development GO:0048339 6 6 0,000 3,66E-03 0,02061504 ! melanosome organization GO:0032438 6 6 0,000 3,66E-03 0,02058257 ! mitochondrial outer membrane translocase complex GO:0005742 6 6 0,000 3,66E-03 0,02055021 ! flotillin complex GO:0016600 6 6 0,000 3,66E-03 0,02051795 ! positive regulation of neuroblast proliferation GO:0002052 6 6 0,000 3,66E-03 0,02048579 ! positive regulation of vasoconstriction GO:0045907 6 6 0,000 3,66E-03 0,02045373 ! negative regulation of DNA recombination GO:0045910 6 6 0,000 3,66E-03 0,02042177 ! positive regulation of exocytosis GO:0045921 7 6 0,000 3,66E-03 0,02038991 ! protein tyrosine kinase activator activity GO:0030296 6 6 0,000 3,66E-03 0,02035815 ! positive regulation of fatty acid metabolic process GO:0045923 6 6 0,000 3,66E-03 0,02032649 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 3,66E-03 0,02029493 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of mitotic cell cycle GO:0045931 6 6 0,000 3,66E-03 0,02026346 ! nonhomologous end joining complex GO:0070419 6 6 0,000 3,66E-03 0,02023209 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! DNA damage response, signal transduction resulting in transcription GO:0042772 9 6 0,000 3,66E-03 0,02020082 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! vinculin binding GO:0017166 6 6 0,000 3,66E-03 0,02016965 ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 3,66E-03 0,02013857 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 3,66E-03 0,02010759 ! sodium ion homeostasis GO:0055078 6 6 0,000 3,66E-03 0,0200767 ! protein heterooligomerization GO:0051291 6 6 0,000 3,66E-03 0,02004591 ! negative regulation of gliogenesis GO:0014014 6 6 0,000 3,66E-03 0,02001521 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 8 6 0,000 3,66E-03 0,01998461 ! translation termination factor activity GO:0008079 6 6 0,000 3,66E-03 0,0199541 GO:0003747|translation release factor activity, ! centrosome duplication GO:0051298 6 6 0,000 3,66E-03 0,01992368 ! astrocyte development GO:0014002 6 6 0,000 3,66E-03 0,01989335 ! protein targeting to lysosome GO:0006622 6 6 0,000 3,66E-03 0,01986312 ! purine base biosynthetic process GO:0009113 7 6 0,000 3,66E-03 0,01983298 ! fibrinolysis GO:0042730 7 6 0,000 3,66E-03 0,01980293 ! peptidyl-asparagine modification GO:0018196 6 6 0,000 3,66E-03 0,01977297 GO:0018279|protein amino acid N-linked glycosylation via asparagine, GO:0004579|dolichyl-diphosphooligosaccharide-protein glycotransferase activity, ! eating behavior GO:0042755 6 6 0,000 3,66E-03 0,0197431 ! B cell lineage commitment GO:0002326 6 6 0,000 3,66E-03 0,01971332 ! thiamin and derivative metabolic process GO:0042723 6 6 0,000 3,66E-03 0,01968363 ! response to exogenous dsRNA GO:0043330 6 6 0,000 3,66E-03 0,01965403 ! melanosome transport GO:0032402 6 6 0,000 3,66E-03 0,01962452 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 6 6 0,000 3,66E-03 0,0195951 GO:0014066|regulation of phosphoinositide 3-kinase cascade, ! mast cell activation GO:0045576 6 6 0,000 3,66E-03 0,01956577 ! regulation of dopamine secretion GO:0014059 6 6 0,000 3,66E-03 0,01953652 ! regulation of protein kinase B signaling cascade GO:0051896 6 6 0,000 3,66E-03 0,01950736 ! negative regulation of focal adhesion formation GO:0051895 8 6 0,000 3,66E-03 0,01947829 ! nucleoside catabolic process GO:0009164 7 6 0,000 3,66E-03 0,01944931 ! transcription initiation factor activity GO:0016986 6 6 0,000 3,66E-03 0,01942041 ! negative regulation of T cell differentiation GO:0045581 6 6 0,000 3,66E-03 0,01939159 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 3,66E-03 0,01936286 ! Schwann cell development GO:0014044 6 6 0,000 3,66E-03 0,01933422 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 6 0,000 3,66E-03 0,01930566 ! G-protein coupled photoreceptor activity GO:0008020 6 6 0,000 3,66E-03 0,01927719 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 3,66E-03 0,0192488 ! regulation of chondrocyte differentiation GO:0032330 6 6 0,000 3,66E-03 0,01922049 ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 3,66E-03 0,01919227 ! nuclear envelope lumen GO:0005641 6 6 0,000 3,66E-03 0,01916412 ! RNA polymerase II transcription elongation factor activity GO:0016944 7 6 0,000 3,66E-03 0,01913607 ! regulation of meiosis GO:0040020 6 6 0,000 3,66E-03 0,01910809 GO:0051445|regulation of meiotic cell cycle, ! establishment of nucleus localization GO:0040023 8 6 0,000 3,66E-03 0,01908019 ! lipoxygenase activity GO:0016165 6 6 0,000 3,66E-03 0,01905238 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 3,66E-03 0,01902465 ! alpha DNA polymerase:primase complex GO:0005658 7 6 0,000 3,66E-03 0,018997 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 3,66E-03 0,01896942 ! nuclear origin of replication recognition complex GO:0005664 6 6 0,000 3,66E-03 0,01894193 GO:0000808|origin recognition complex, ! DNA replication factor A complex GO:0005662 6 6 0,000 3,66E-03 0,01891452 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 3,66E-03 0,01888719 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 3,66E-03 0,01885993 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 3,66E-03 0,01883276 ! chromatin silencing complex GO:0005677 6 6 0,000 3,66E-03 0,01880566 GO:0034979|NAD-dependent protein deacetylase activity, GO:0017136|NAD-dependent histone deacetylase activity, ! U12-type spliceosomal complex GO:0005689 7 6 0,000 3,66E-03 0,01877864 ! regulation of respiratory burst GO:0060263 6 6 0,000 3,66E-03 0,0187517 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 10 6 0,000 3,66E-03 0,01872483 GO:0002820|negative regulation of adaptive immune response, ! immunological synapse GO:0001772 6 6 0,000 3,66E-03 0,01869804 ! MutLalpha complex GO:0032389 6 6 0,000 3,66E-03 0,01867133 ! leading edge membrane GO:0031256 6 6 0,000 3,66E-03 0,0186447 ! bis(5'-adenosyl)-triphosphatase activity GO:0047710 6 6 0,000 3,66E-03 0,01861814 ! peptidyl-histidine modification GO:0018202 6 6 0,000 3,66E-03 0,01859165 ! exodeoxyribonuclease activity GO:0004529 6 6 0,000 3,66E-03 0,01856525 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! COPII vesicle coat GO:0030127 6 6 0,000 3,66E-03 0,01853891 GO:0012507|ER to Golgi transport vesicle membrane, ! peptidyl-threonine modification GO:0018210 6 6 0,000 3,66E-03 0,01851265 ! diuresis GO:0030146 6 6 0,000 3,66E-03 0,01848647 GO:0030147|natriuresis, ! glutathione biosynthetic process GO:0006750 6 6 0,000 3,66E-03 0,01846036 ! HLA-B specific inhibitory MHC class I receptor activity GO:0030109 6 6 0,000 3,66E-03 0,01843432 ! BBSome GO:0034464 6 6 0,000 3,66E-03 0,01840836 ! regulation of keratinocyte differentiation GO:0045616 6 6 0,000 3,66E-03 0,01838247 ! glycerophosphodiester phosphodiesterase activity GO:0008889 6 6 0,000 3,66E-03 0,01835665 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 3,66E-03 0,0183309 ! sodium channel regulator activity GO:0017080 6 6 0,000 3,66E-03 0,01830523 ! glycolipid catabolic process GO:0019377 6 6 0,000 3,66E-03 0,01827963 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 6 6 0,000 3,66E-03 0,0182541 ! nicotinamide nucleotide biosynthetic process GO:0019359 6 6 0,000 3,66E-03 0,01822864 ! porphyrin catabolic process GO:0006787 8 6 0,000 3,66E-03 0,01820325 GO:0033015|tetrapyrrole catabolic process, ! removal of superoxide radicals GO:0019430 6 6 0,000 3,66E-03 0,01817793 ! positive regulation of glucose import GO:0046326 7 6 0,000 3,66E-03 0,01815268 GO:0010828|positive regulation of glucose transport, ! triglyceride catabolic process GO:0019433 6 6 0,000 3,66E-03 0,01812751 ! myeloid cell homeostasis GO:0002262 6 6 0,000 3,66E-03 0,0181024 ! lamin binding GO:0005521 6 6 0,000 3,66E-03 0,01807736 ! ectodermal gut morphogenesis GO:0048567 6 6 0,000 3,66E-03 0,01805239 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 6 6 0,000 3,66E-03 0,01802749 ! pattern recognition receptor signaling pathway GO:0002221 6 6 0,000 3,66E-03 0,01800266 ! negative regulation of calcium ion transport GO:0051926 6 6 0,000 3,66E-03 0,0179779 ! peroxiredoxin activity GO:0051920 6 6 0,000 3,66E-03 0,0179532 ! complement binding GO:0001848 8 6 0,000 3,66E-03 0,01792858 ! catecholamine transport GO:0051937 6 6 0,000 3,66E-03 0,01790402 ! regulation of sensory perception GO:0051931 6 6 0,000 3,66E-03 0,01787953 GO:0051930|regulation of sensory perception of pain, ! muscle adaptation GO:0043500 6 6 0,000 3,66E-03 0,0178551 ! hemopoietic progenitor cell differentiation GO:0002244 6 6 0,000 3,66E-03 0,01783074 ! dipeptidase activity GO:0016805 6 6 0,000 3,66E-03 0,01780645 ! ether hydrolase activity GO:0016803 6 6 0,000 3,66E-03 0,01778222 ! FACIT collagen GO:0005593 6 6 0,000 3,66E-03 0,01775806 ! actin filament polymerization GO:0030041 8 6 0,000 3,66E-03 0,01773397 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 3,66E-03 0,01770994 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 6 6 0,000 3,66E-03 0,01768597 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 6 0,000 3,66E-03 0,01766207 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 3,66E-03 0,01763824 ! negative regulation of synaptic transmission GO:0050805 7 6 0,000 3,66E-03 0,01761447 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 3,66E-03 0,01759076 ! organ regeneration GO:0031100 6 6 0,000 3,66E-03 0,01756711 ! Golgi transport complex GO:0017119 6 6 0,000 3,66E-03 0,01754353 ! sheet-forming collagen GO:0030935 6 6 0,000 3,66E-03 0,01752002 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 3,66E-03 0,01749656 ! positive regulation of coagulation GO:0050820 7 6 0,000 3,66E-03 0,01747317 ! defense response to Gram-negative bacterium GO:0050829 6 6 0,000 3,66E-03 0,01744984 ! positive regulation of MHC class II biosynthetic process GO:0045348 6 6 0,000 3,66E-03 0,01742658 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 6 6 0,000 3,66E-03 0,01740337 ! thioredoxin-disulfide reductase activity GO:0004791 6 6 0,000 3,66E-03 0,01738023 ! sphingomyelin phosphodiesterase activity GO:0004767 7 6 0,000 3,66E-03 0,01735715 ! regulation of cGMP metabolic process GO:0030823 6 6 0,000 3,66E-03 0,01733413 ! myoblast cell fate commitment GO:0048625 6 6 0,000 3,66E-03 0,01731117 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 3,66E-03 0,01728827 ! DNA synthesis during DNA repair GO:0000731 7 6 0,000 3,66E-03 0,01726543 ! neutral lipid biosynthetic process GO:0046460 6 6 0,000 3,66E-03 0,01724266 GO:0046463|acylglycerol biosynthetic process, ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 6 6 0,000 3,66E-03 0,01721994 ! nuclear telomere cap complex GO:0000783 6 6 0,000 3,66E-03 0,01719728 GO:0000782|telomere cap complex, ! Golgi to endosome transport GO:0006895 6 6 0,000 3,66E-03 0,01717468 ! negative regulation of JAK-STAT cascade GO:0046426 7 6 0,000 3,66E-03 0,01715214 ! sterol carrier activity GO:0005498 6 6 0,000 3,66E-03 0,01712966 ! positive regulation of cell-cell adhesion GO:0022409 6 6 0,000 3,66E-03 0,01710724 ! succinate metabolic process GO:0006105 6 6 0,000 3,66E-03 0,01708488 ! myelin sheath GO:0043209 6 6 0,000 3,66E-03 0,01706258 ! perikaryon GO:0043204 7 6 0,000 3,66E-03 0,01704033 ! oxaloacetate metabolic process GO:0006107 7 6 0,000 3,66E-03 0,01701814 ! malate metabolic process GO:0006108 6 6 0,000 3,66E-03 0,01699601 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 6 6 0,000 3,66E-03 0,01697394 ! posttranscriptional gene silencing by RNA GO:0035194 6 6 0,000 3,66E-03 0,01695192 GO:0016441|posttranscriptional gene silencing, ! mating behavior GO:0007617 6 6 0,000 3,66E-03 0,01692997 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 3,66E-03 0,01690806 ! rhythmic behavior GO:0007622 7 6 0,000 3,66E-03 0,01688622 ! copulation GO:0007620 6 6 0,000 3,66E-03 0,01686443 ! erythrocyte maturation GO:0043249 6 6 0,000 3,66E-03 0,0168427 ! equilibrioception GO:0050957 6 6 0,000 3,66E-03 0,01682102 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 3,66E-03 0,0167994 ! G-protein coupled receptor kinase activity GO:0004703 6 6 0,000 3,66E-03 0,01677783 ! chemosensory behavior GO:0007635 6 6 0,000 3,66E-03 0,01675632 ! synaptic transmission, dopaminergic GO:0001963 7 6 0,000 3,66E-03 0,01673487 ! mechanosensory behavior GO:0007638 6 6 0,000 3,66E-03 0,01671347 ! response to interferon-gamma GO:0034341 6 6 0,000 3,66E-03 0,01669212 ! spinal cord patterning GO:0021511 6 6 0,000 3,66E-03 0,01667083 ! cGMP-mediated signaling GO:0019934 6 6 0,000 3,66E-03 0,0166496 ! protein geranylgeranyltransferase activity GO:0004661 6 6 0,000 3,66E-03 0,01662841 ! activation of MAPKKK activity GO:0000185 6 6 0,000 3,66E-03 0,01660728 ! nerve growth factor receptor signaling pathway GO:0048011 8 6 0,000 3,66E-03 0,01658621 ! glucosyltransferase activity GO:0046527 6 6 0,000 3,66E-03 0,01656519 ! sphingoid catabolic process GO:0046521 6 6 0,000 3,66E-03 0,01654422 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 3,66E-03 0,0165233 ! activin receptor activity GO:0017002 6 6 0,000 3,66E-03 0,01650244 ! ovulation GO:0030728 6 6 0,000 3,66E-03 0,01648163 ! dopamine binding GO:0035240 7 6 0,000 3,66E-03 0,01646087 ! hyperosmotic response GO:0006972 6 6 0,000 3,66E-03 0,01644017 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 6 6 0,000 3,66E-03 0,01641951 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 6 0,000 3,66E-03 0,01639891 ! nuclear localization sequence binding GO:0008139 6 6 0,000 3,66E-03 0,01637836 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 3,66E-03 0,01635786 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 3,66E-03 0,01633742 ! copper ion transmembrane transporter activity GO:0005375 6 6 0,000 3,66E-03 0,01631702 ! poly(A) RNA binding GO:0008143 6 6 0,000 3,66E-03 0,01629667 ! positive transcription elongation factor activity GO:0008159 6 6 0,000 3,66E-03 0,01627638 ! regulation of glycogen metabolic process GO:0070873 7 6 0,000 3,66E-03 0,01625614 GO:0032881|regulation of polysaccharide metabolic process, ! maintenance of protein location in nucleus GO:0051457 6 6 0,000 3,66E-03 0,01623594 ! intracellular pH reduction GO:0051452 6 6 0,000 3,66E-03 0,0162158 GO:0045851|pH reduction, ! purine salvage GO:0043101 8 6 0,000 3,66E-03 0,0161957 ! nucleotide-sugar transmembrane transporter activity GO:0005338 6 6 0,000 3,66E-03 0,01617566 ! neurotrophin binding GO:0043121 6 6 0,000 3,66E-03 0,01615567 ! ciliary rootlet GO:0035253 6 6 0,000 3,66E-03 0,01613572 ! neurotransmitter catabolic process GO:0042135 10 6 0,000 3,66E-03 0,01611582 ! ruffle organization GO:0031529 6 6 0,000 3,66E-03 0,01609598 ! T cell mediated immunity GO:0002456 6 6 0,000 3,66E-03 0,01607618 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 7 6 0,000 3,66E-03 0,01605643 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! carnitine transport GO:0015879 6 6 0,000 3,66E-03 0,01603673 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 3,66E-03 0,01601707 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! palmitoyl-CoA hydrolase activity GO:0016290 6 6 0,000 3,66E-03 0,01599747 ! S-methyltransferase activity GO:0008172 6 6 0,000 3,66E-03 0,01597791 ! phospholipase D activity GO:0004630 6 6 0,000 3,66E-03 0,0159584 ! rRNA modification GO:0000154 6 6 0,000 3,66E-03 0,01593894 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 3,66E-03 0,01591953 ! neuronal ion channel clustering GO:0045161 6 6 0,000 3,66E-03 0,01590016 ! response to UV-B GO:0010224 6 6 0,000 3,66E-03 0,01588084 ! interaction with symbiont GO:0051702 6 6 0,000 3,66E-03 0,01586157 ! negative regulation of insulin receptor signaling pathway GO:0046627 6 6 0,000 3,66E-03 0,01584234 ! IgG binding GO:0019864 6 6 0,000 3,66E-03 0,01582316 ! positive regulation of cytokine production during immune response GO:0002720 6 6 0,000 3,66E-03 0,01580403 ! base-excision repair, AP site formation GO:0006285 6 6 0,000 3,66E-03 0,01578494 ! benzodiazepine receptor activity GO:0008503 6 6 0,000 3,66E-03 0,0157659 ! response to copper ion GO:0046688 6 6 0,000 3,66E-03 0,01574691 ! DNA topological change GO:0006265 6 6 0,000 3,66E-03 0,01572796 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 3,66E-03 0,01570905 ! dendrite morphogenesis GO:0048813 6 6 0,000 3,66E-03 0,0156902 ! regulation of interleukin-1 beta production GO:0032651 6 6 0,000 3,66E-03 0,01567138 ! regulation of myeloid cell apoptosis GO:0033032 6 6 0,000 3,66E-03 0,01565261 ! positive regulation of tumor necrosis factor production GO:0032760 6 6 0,000 3,66E-03 0,01563389 ! nucleosome disassembly GO:0006337 6 6 0,000 3,66E-03 0,01561521 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! inositol trisphosphate 3-kinase activity GO:0008440 6 6 0,000 3,66E-03 0,01559658 ! regulation of mast cell activation GO:0033003 6 6 0,000 3,66E-03 0,01557799 ! guanylyltransferase activity GO:0070568 6 6 0,000 3,66E-03 0,01555944 ! receptor internalization GO:0031623 7 6 0,000 3,66E-03 0,01554094 ! neuropeptide Y receptor activity GO:0004983 6 6 0,000 3,66E-03 0,01552249 ! ATP-dependent peptidase activity GO:0004176 6 6 0,000 3,66E-03 0,01550407 ! serine-type carboxypeptidase activity GO:0004185 6 6 0,000 3,66E-03 0,0154857 GO:0070008|serine-type exopeptidase activity, ! protein deubiquitination GO:0016579 6 6 0,000 3,66E-03 0,01546738 ! negative regulation of neuroblast proliferation GO:0007406 6 6 0,000 3,66E-03 0,01544909 ! NuRD complex GO:0016581 6 6 0,000 3,66E-03 0,01543085 ! nucleosome positioning GO:0016584 6 6 0,000 3,66E-03 0,01541266 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 3,66E-03 0,0153945 ! alpha-adrenergic receptor activity GO:0004936 8 6 0,000 3,66E-03 0,01537639 ! glycine binding GO:0016594 8 6 0,000 3,66E-03 0,01535832 ! costamere GO:0043034 7 6 0,000 3,66E-03 0,0153403 ! A band GO:0031672 6 6 0,000 3,66E-03 0,01532231 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 3,66E-03 0,01530437 ! dopamine biosynthetic process GO:0042416 7 6 0,000 3,66E-03 0,01528647 ! procollagen-proline dioxygenase activity GO:0019798 6 6 0,000 3,66E-03 0,01526861 ! negative regulation of axon extension GO:0030517 6 6 0,000 3,66E-03 0,0152508 ! actin monomer binding GO:0003785 6 6 0,000 3,66E-03 0,01523302 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 3,66E-03 0,01521529 ! lysozyme activity GO:0003796 6 6 0,000 3,66E-03 0,0151976 ! regulation of Rac protein signal transduction GO:0035020 6 6 0,000 3,66E-03 0,01517995 ! ATP catabolic process GO:0006200 6 6 0,000 3,66E-03 0,01516234 ! determination of adult lifespan GO:0008340 6 6 0,000 3,66E-03 0,01514477 ! somatic stem cell maintenance GO:0035019 6 6 0,000 3,66E-03 0,01512724 ! negative regulation of organic acid transport GO:0032891 6 6 0,000 3,66E-03 0,01510975 ! establishment of apical/basal cell polarity GO:0035089 6 6 0,000 3,66E-03 0,0150923 ! calcium-dependent phospholipase A2 activity GO:0047498 6 6 0,000 3,66E-03 0,01507489 ! O-acetyltransferase activity GO:0016413 6 6 0,000 3,66E-03 0,01505753 ! CoA-ligase activity GO:0016405 6 6 0,000 3,66E-03 0,0150402 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 3,66E-03 0,01502291 ! IkappaB kinase complex GO:0008385 6 6 0,000 3,66E-03 0,01500566 ! pyrimidine nucleotide catabolic process GO:0006244 6 6 0,000 3,66E-03 0,01498846 ! store-operated calcium channel activity GO:0015279 6 6 0,000 3,66E-03 0,01497129 ! aminomethyltransferase activity GO:0004047 6 6 0,000 3,66E-03 0,01495416 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 6 6 0,000 3,66E-03 0,01493707 ! alkaline phosphatase activity GO:0004035 6 6 0,000 3,66E-03 0,01492001 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 6 6 0,000 3,66E-03 0,014903 ! oligosaccharide biosynthetic process GO:0009312 7 7 0,000 4,269E-03 0,01736232 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 4,269E-03 0,01734257 ! sleep GO:0030431 7 7 0,000 4,269E-03 0,01732286 ! synaptonemal complex assembly GO:0007130 7 7 0,000 4,269E-03 0,0173032 GO:0070193|synaptonemal complex organization, ! forebrain regionalization GO:0021871 7 7 0,000 4,269E-03 0,01728358 ! cell proliferation in forebrain GO:0021846 7 7 0,000 4,269E-03 0,017264 ! proteasome regulatory particle GO:0005838 8 7 0,000 4,269E-03 0,01724448 ! meiotic prophase I GO:0007128 7 7 0,000 4,269E-03 0,01722499 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 7 0,000 4,269E-03 0,01720555 ! SMAD protein nuclear translocation GO:0007184 8 7 0,000 4,269E-03 0,01718615 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 7 7 0,000 4,269E-03 0,0171668 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 4,269E-03 0,01714749 ! diphosphotransferase activity GO:0016778 8 7 0,000 4,269E-03 0,01712822 ! actin-myosin filament sliding GO:0033275 7 7 0,000 4,269E-03 0,017109 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! signal peptide processing GO:0006465 7 7 0,000 4,269E-03 0,01708982 ! glycine hydroxymethyltransferase activity GO:0004372 8 7 0,000 4,269E-03 0,01707068 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 4,269E-03 0,01705158 ! macrophage chemotaxis GO:0048246 7 7 0,000 4,269E-03 0,01703253 ! cerebral cortex cell migration GO:0021795 7 7 0,000 4,269E-03 0,01701352 ! tachykinin receptor signaling pathway GO:0007217 7 7 0,000 4,269E-03 0,01699456 ! membrane hyperpolarization GO:0060081 7 7 0,000 4,269E-03 0,01697563 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 4,269E-03 0,01695675 ! enoyl-CoA hydratase activity GO:0004300 7 7 0,000 4,269E-03 0,01693791 ! DNA replication origin binding GO:0003688 7 7 0,000 4,269E-03 0,01691911 ! ATPase binding GO:0051117 7 7 0,000 4,269E-03 0,01690035 ! positive regulation of glycolysis GO:0045821 7 7 0,000 4,269E-03 0,01688163 ! positive regulation of isotype switching GO:0045830 11 7 0,000 4,269E-03 0,01686296 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 8 7 0,000 4,269E-03 0,01684433 ! ribonucleoside triphosphate catabolic process GO:0009203 7 7 0,000 4,269E-03 0,01682574 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! protein-cofactor linkage GO:0018065 7 7 0,000 4,269E-03 0,01680718 ! positive regulation of chemokine biosynthetic process GO:0045080 7 7 0,000 4,269E-03 0,01678867 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 7 7 0,000 4,269E-03 0,0167702 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! thymic T cell selection GO:0045061 11 7 0,000 4,269E-03 0,01675178 ! structural constituent of tooth enamel GO:0030345 7 7 0,000 4,269E-03 0,01673339 ! transepithelial chloride transport GO:0030321 7 7 0,000 4,269E-03 0,01671504 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 4,269E-03 0,01669673 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 4,269E-03 0,01667846 ! glycine catabolic process GO:0006546 7 7 0,000 4,269E-03 0,01666024 GO:0009071|serine family amino acid catabolic process, ! deoxyribonucleotide biosynthetic process GO:0009263 8 7 0,000 4,269E-03 0,01664205 ! cytoskeletal anchoring at plasma membrane GO:0007016 8 7 0,000 4,269E-03 0,0166239 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 4,269E-03 0,01660579 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! polyamine biosynthetic process GO:0006596 7 7 0,000 4,269E-03 0,01658772 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 7 7 0,000 4,269E-03 0,01656969 ! endosome organization GO:0007032 7 7 0,000 4,269E-03 0,0165517 ! thyroid hormone generation GO:0006590 7 7 0,000 4,269E-03 0,01653375 ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 4,269E-03 0,01651584 GO:0021940|positive regulation of granule cell precursor proliferation, ! reverse cholesterol transport GO:0043691 7 7 0,000 4,269E-03 0,01649796 ! tumor necrosis factor receptor activity GO:0005031 7 7 0,000 4,269E-03 0,01648013 ! indolalkylamine metabolic process GO:0006586 7 7 0,000 4,269E-03 0,01646233 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! proton-transporting V-type ATPase, V1 domain GO:0033180 7 7 0,000 4,269E-03 0,01644457 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 4,269E-03 0,01642685 ! retinoid X receptor binding GO:0046965 7 7 0,000 4,269E-03 0,01640917 ! central nervous system neuron axonogenesis GO:0021955 7 7 0,000 4,269E-03 0,01639152 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 4,269E-03 0,01637392 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! regulation of phosphoprotein phosphatase activity GO:0043666 7 7 0,000 4,269E-03 0,01635635 GO:0010921|regulation of phosphatase activity, ! platelet-derived growth factor receptor activity GO:0005017 7 7 0,000 4,269E-03 0,01633882 ! urea metabolic process GO:0019627 7 7 0,000 4,269E-03 0,01632132 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! retinoic acid receptor signaling pathway GO:0048384 7 7 0,000 4,269E-03 0,01630387 ! regulation of type I interferon production GO:0032479 8 7 0,000 4,269E-03 0,01628645 ! peroxisomal matrix GO:0005782 7 7 0,000 4,269E-03 0,01626907 GO:0031907|microbody lumen, ! methyltransferase complex GO:0034708 7 7 0,000 4,269E-03 0,01625172 GO:0035097|histone methyltransferase complex, ! response to dietary excess GO:0002021 7 7 0,000 4,269E-03 0,01623442 ! p53 binding GO:0002039 7 7 0,000 4,269E-03 0,01621715 ! osteoblast development GO:0002076 8 7 0,000 4,269E-03 0,01619991 ! positive regulation of nitric-oxide synthase activity GO:0051000 7 7 0,000 4,269E-03 0,01618271 ! lipid phosphatase activity GO:0042577 7 7 0,000 4,269E-03 0,01616555 ! male sex determination GO:0030238 7 7 0,000 4,269E-03 0,01614843 ! clathrin binding GO:0030276 8 7 0,000 4,269E-03 0,01613134 ! negative regulation of translational initiation GO:0045947 7 7 0,000 4,269E-03 0,01611429 ! determination of anterior/posterior axis, embryo GO:0008595 7 7 0,000 4,269E-03 0,01609727 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 7 7 0,000 4,269E-03 0,01608029 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 4,269E-03 0,01606335 GO:0030204|chondroitin sulfate metabolic process, ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 4,269E-03 0,01604644 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 4,269E-03 0,01602957 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 4,269E-03 0,01601273 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 4,269E-03 0,01599592 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 8 7 0,000 4,269E-03 0,01597916 ! hyaluronan metabolic process GO:0030212 8 7 0,000 4,269E-03 0,01596243 ! protein retention in ER lumen GO:0006621 7 7 0,000 4,269E-03 0,01594573 ! cardiac muscle cell differentiation GO:0055007 7 7 0,000 4,269E-03 0,01592907 ! peptidyl-arginine modification GO:0018195 7 7 0,000 4,269E-03 0,01591244 ! regulation of circadian rhythm GO:0042752 7 7 0,000 4,269E-03 0,01589585 ! Hsp90 protein binding GO:0051879 7 7 0,000 4,269E-03 0,01587929 ! MutSalpha complex binding GO:0032407 8 7 0,000 4,269E-03 0,01586276 ! regulation of fat cell differentiation GO:0045598 7 7 0,000 4,269E-03 0,01584627 ! establishment of melanosome localization GO:0032401 7 7 0,000 4,269E-03 0,01582982 ! regulation of focal adhesion formation GO:0051893 9 7 0,000 4,269E-03 0,0158134 ! gas homeostasis GO:0033483 7 7 0,000 4,269E-03 0,01579701 ! cranial nerve morphogenesis GO:0021602 7 7 0,000 4,269E-03 0,01578066 ! subpallium development GO:0021544 7 7 0,000 4,269E-03 0,01576434 ! laminin-1 complex GO:0005606 7 7 0,000 4,269E-03 0,01574805 GO:0043256|laminin complex, ! molybdopterin cofactor biosynthetic process GO:0032324 7 7 0,000 4,269E-03 0,0157318 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 8 7 0,000 4,269E-03 0,01571558 ! eye photoreceptor cell differentiation GO:0001754 10 7 0,000 4,269E-03 0,0156994 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 7 7 0,000 4,269E-03 0,01568325 ! positive regulation of immunoglobulin mediated immune response GO:0002891 11 7 0,000 4,269E-03 0,01566713 GO:0002714|positive regulation of B cell mediated immunity, ! protein sumoylation GO:0016925 7 7 0,000 4,269E-03 0,01565104 ! establishment of chromosome localization GO:0051303 7 7 0,000 4,269E-03 0,01563499 GO:0050000|chromosome localization, ! regulation of lipid transport GO:0032368 7 7 0,000 4,269E-03 0,01561897 ! regulation of cell division GO:0051302 7 7 0,000 4,269E-03 0,01560298 ! chromatin assembly complex GO:0005678 7 7 0,000 4,269E-03 0,01558703 ! sex chromatin GO:0001739 7 7 0,000 4,269E-03 0,01557111 GO:0000803|sex chromosome, ! oligosaccharyl transferase activity GO:0004576 7 7 0,000 4,269E-03 0,01555522 ! chitinase activity GO:0004568 7 7 0,000 4,269E-03 0,01553936 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 7 7 0,000 4,269E-03 0,01552354 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 7 7 0,000 4,269E-03 0,01550775 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 10 7 0,000 4,269E-03 0,01549199 ! inhibitory MHC class I receptor activity GO:0032396 7 7 0,000 4,269E-03 0,01547626 GO:0030110|HLA-C specific inhibitory MHC class I receptor activity, ! ER to Golgi transport vesicle GO:0030134 7 7 0,000 4,269E-03 0,01546056 ! molybdenum ion binding GO:0030151 7 7 0,000 4,269E-03 0,0154449 ! centriolar satellite GO:0034451 8 7 0,000 4,269E-03 0,01542927 ! positive regulation of epidermis development GO:0045684 7 7 0,000 4,269E-03 0,01541367 ! proteasome regulator activity GO:0010860 7 7 0,000 4,269E-03 0,0153981 ! antibiotic transport GO:0042891 7 7 0,000 4,269E-03 0,01538256 ! negative regulation of transmission of nerve impulse GO:0051970 8 7 0,000 4,269E-03 0,01536705 ! regulation of synaptic transmission, glutamatergic GO:0051966 7 7 0,000 4,269E-03 0,01535158 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 4,269E-03 0,01533613 ! aspartate family amino acid catabolic process GO:0009068 7 7 0,000 4,269E-03 0,01532072 ! Wnt receptor activity GO:0042813 7 7 0,000 4,269E-03 0,01530534 ! regulation of protein homodimerization activity GO:0043496 7 7 0,000 4,269E-03 0,01528999 ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 7 7 0,000 4,269E-03 0,01527467 ! positive regulation of viral reproduction GO:0048524 7 7 0,000 4,269E-03 0,01525938 ! negative regulation of viral reproduction GO:0048525 7 7 0,000 4,269E-03 0,01524412 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 9 7 0,000 4,269E-03 0,01522889 ! blastocyst growth GO:0001832 7 7 0,000 4,269E-03 0,01521369 ! pigment granule transport GO:0051904 7 7 0,000 4,269E-03 0,01519852 ! lymphocyte activation during immune response GO:0002285 7 7 0,000 4,269E-03 0,01518338 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 4,269E-03 0,01516827 ! negative regulation of fibrinolysis GO:0051918 7 7 0,000 4,269E-03 0,0151532 ! negative regulation of telomere maintenance GO:0032205 7 7 0,000 4,269E-03 0,01513815 ! cerebellar cortex formation GO:0021697 8 7 0,000 4,269E-03 0,01512313 ! activation of innate immune response GO:0002218 7 7 0,000 4,269E-03 0,01510814 GO:0002758|innate immune response-activating signal transduction, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 7 7 0,000 4,269E-03 0,01509318 ! natural killer cell mediated immunity GO:0002228 7 7 0,000 4,269E-03 0,01507826 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of synaptic transmission, dopaminergic GO:0032225 7 7 0,000 4,269E-03 0,01506336 ! regulation of synaptic transmission, GABAergic GO:0032228 7 7 0,000 4,269E-03 0,01504849 ! flavin-containing monooxygenase activity GO:0004499 7 7 0,000 4,269E-03 0,01503365 ! regulation of muscle adaptation GO:0043502 7 7 0,000 4,269E-03 0,01501883 ! sequestering of metal ion GO:0051238 7 7 0,000 4,269E-03 0,01500405 ! regulation of T cell receptor signaling pathway GO:0050856 8 7 0,000 4,269E-03 0,0149893 ! membrane attack complex GO:0005579 7 7 0,000 4,269E-03 0,01497457 ! fibrinogen complex GO:0005577 7 7 0,000 4,269E-03 0,01495988 ! septin complex GO:0031105 9 7 0,000 4,269E-03 0,01494521 GO:0032156|septin cytoskeleton, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 7 7 0,000 4,269E-03 0,01493057 ! positive regulation of microtubule polymerization GO:0031116 7 7 0,000 4,269E-03 0,01491597 ! cellular anion homeostasis GO:0030002 7 7 0,000 4,269E-03 0,01490138 GO:0055081|anion homeostasis, ! positive regulation of cyclic nucleotide metabolic process GO:0030801 7 7 0,000 4,269E-03 0,01488683 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! behavioral response to cocaine GO:0048148 9 7 0,000 4,269E-03 0,01487231 ! autophagic vacuole formation GO:0000045 8 7 0,000 4,269E-03 0,01485781 ! negative regulation of smooth muscle cell proliferation GO:0048662 7 7 0,000 4,269E-03 0,01484335 ! translation initiation factor binding GO:0031369 7 7 0,000 4,269E-03 0,01482891 ! regulation of lipid catabolic process GO:0050994 7 7 0,000 4,269E-03 0,0148145 ! activin binding GO:0048185 7 7 0,000 4,269E-03 0,01480011 ! syncytium formation by plasma membrane fusion GO:0000768 7 7 0,000 4,269E-03 0,01478576 GO:0007520|myoblast fusion, ! nucleotide-excision repair, DNA incision GO:0033683 7 7 0,000 4,269E-03 0,01477143 ! oligosaccharyltransferase complex GO:0008250 7 7 0,000 4,269E-03 0,01475713 ! phototransduction, visible light GO:0007603 7 7 0,000 4,269E-03 0,01474286 ! positive regulation of neurotransmitter transport GO:0051590 7 7 0,000 4,269E-03 0,01472861 ! lipoprotein transport GO:0042953 7 7 0,000 4,269E-03 0,0147144 ! cell division site part GO:0032155 7 7 0,000 4,269E-03 0,01470021 GO:0032153|cell division site, ! laminin binding GO:0043236 9 7 0,000 4,269E-03 0,01468605 ! detection of mechanical stimulus involved in sensory perception GO:0050974 7 7 0,000 4,269E-03 0,01467191 ! phospholipid efflux GO:0033700 7 7 0,000 4,269E-03 0,0146578 ! DNA insertion or deletion binding GO:0032135 7 7 0,000 4,269E-03 0,01464372 GO:0032138|single base insertion or deletion binding, ! glucocorticoid metabolic process GO:0008211 7 7 0,000 4,269E-03 0,01462967 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 7 7 0,000 4,269E-03 0,01461564 ! poly-purine tract binding GO:0070717 7 7 0,000 4,269E-03 0,01460164 ! T-helper 1 type immune response GO:0042088 7 7 0,000 4,269E-03 0,01458767 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 4,269E-03 0,01457372 GO:0032107|regulation of response to nutrient levels, ! amyloid precursor protein catabolic process GO:0042987 7 7 0,000 4,269E-03 0,01455981 ! leukocyte degranulation GO:0043299 7 7 0,000 4,269E-03 0,01454591 ! sodium:phosphate symporter activity GO:0005436 7 7 0,000 4,269E-03 0,01453205 ! bile acid and bile salt transport GO:0015721 7 7 0,000 4,269E-03 0,01451821 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 4,269E-03 0,01450439 ! glycerol ether biosynthetic process GO:0046504 7 7 0,000 4,269E-03 0,0144906 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 4,269E-03 0,01447684 GO:0046513|ceramide biosynthetic process, ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 4,269E-03 0,01446311 ! pigment granule organization GO:0048753 7 7 0,000 4,269E-03 0,0144494 ! eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 7 7 0,000 4,269E-03 0,01443572 ! regulation of interleukin-8 biosynthetic process GO:0045414 8 7 0,000 4,269E-03 0,01442206 ! regulation of pigmentation during development GO:0048070 10 7 0,000 4,269E-03 0,01440843 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 7 7 0,000 4,269E-03 0,01439482 ! macrophage activation GO:0042116 7 7 0,000 4,269E-03 0,01438124 ! positive regulation of activated T cell proliferation GO:0042104 7 7 0,000 4,269E-03 0,01436769 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 7 7 0,000 4,269E-03 0,01435416 ! galactose metabolic process GO:0006012 7 7 0,000 4,269E-03 0,01434066 ! vesicle fusion GO:0006906 7 7 0,000 4,269E-03 0,01432718 ! positive regulation of insulin secretion GO:0032024 7 7 0,000 4,269E-03 0,01431372 ! glycerol ether catabolic process GO:0044269 7 7 0,000 4,269E-03 0,0143003 GO:0046464|acylglycerol catabolic process, ! virus-infected cell apoptosis GO:0006926 7 7 0,000 4,269E-03 0,01428689 ! NuA4 histone acetyltransferase complex GO:0035267 8 7 0,000 4,269E-03 0,01427352 ! nucleoside transmembrane transporter activity GO:0005337 7 7 0,000 4,269E-03 0,01426016 GO:0015858|nucleoside transport, ! regulation of vascular permeability GO:0043114 7 7 0,000 4,269E-03 0,01424684 ! regulation of multicellular organismal metabolic process GO:0044246 8 7 0,000 4,269E-03 0,01423354 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 4,269E-03 0,01422026 ! peptidyl-proline dioxygenase activity GO:0031543 7 7 0,000 4,269E-03 0,014207 ! inclusion body GO:0016234 7 7 0,000 4,269E-03 0,01419378 ! parturition GO:0007567 7 7 0,000 4,269E-03 0,01418057 ! tRNA methyltransferase activity GO:0008175 7 7 0,000 4,269E-03 0,01416739 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 7 7 0,000 4,269E-03 0,01415424 ! intercalated disc GO:0014704 8 7 0,000 4,269E-03 0,01414111 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 4,269E-03 0,014128 ! neural nucleus development GO:0048857 7 7 0,000 4,269E-03 0,01411492 ! intermediate filament organization GO:0045109 8 7 0,000 4,269E-03 0,01410187 ! skeletal muscle contraction GO:0003009 7 7 0,000 4,269E-03 0,01408883 ! response to antibiotic GO:0046677 7 7 0,000 4,269E-03 0,01407582 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 7 7 0,000 4,269E-03 0,01406284 ! preribosome GO:0030684 7 7 0,000 4,269E-03 0,01404988 ! positive regulation of production of molecular mediator of immune response GO:0002702 7 7 0,000 4,269E-03 0,01403694 ! hydrogen-exporting ATPase activity, phosphorylative mechanism GO:0008553 7 7 0,000 4,269E-03 0,01402403 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 7 7 0,000 4,269E-03 0,01401114 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 4,269E-03 0,01399827 ! regulation of interleukin-1 production GO:0032652 7 7 0,000 4,269E-03 0,01398543 ! phosphofructokinase activity GO:0008443 7 7 0,000 4,269E-03 0,01397261 ! postreplication repair GO:0006301 7 7 0,000 4,269E-03 0,01395981 ! gap junction channel activity GO:0005243 7 7 0,000 4,269E-03 0,01394704 ! transcription from RNA polymerase I promoter GO:0006360 7 7 0,000 4,269E-03 0,01393429 ! mitochondrion morphogenesis GO:0070584 8 7 0,000 4,269E-03 0,01392157 ! transcription termination GO:0006353 8 7 0,000 4,269E-03 0,01390887 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 7 7 0,000 4,269E-03 0,01389619 ! tetracycline transporter activity GO:0008493 7 7 0,000 4,269E-03 0,01388353 GO:0042895|antibiotic transporter activity, ! cytidylyltransferase activity GO:0070567 7 7 0,000 4,269E-03 0,0138709 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 4,269E-03 0,01385829 ! melanocortin receptor activity GO:0004977 7 7 0,000 4,269E-03 0,0138457 ! coenzyme A metabolic process GO:0015936 8 7 0,000 4,269E-03 0,01383314 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 7 0,000 4,269E-03 0,0138206 ! regulation of macrophage activation GO:0043030 7 7 0,000 4,269E-03 0,01380808 ! cytidine deaminase activity GO:0004126 7 7 0,000 4,269E-03 0,01379558 ! inositol trisphosphate kinase activity GO:0051766 7 7 0,000 4,269E-03 0,01378311 ! apical protein localization GO:0045176 7 7 0,000 4,269E-03 0,01377066 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 4,269E-03 0,01375823 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 4,269E-03 0,01374582 ! virion binding GO:0046790 10 7 0,000 4,269E-03 0,01373344 ! nonprotein amino acid metabolic process GO:0019794 7 7 0,000 4,269E-03 0,01372108 ! protein prenyltransferase activity GO:0008318 7 7 0,000 4,269E-03 0,01370874 ! protein modification by small protein removal GO:0070646 7 7 0,000 4,269E-03 0,01369642 ! adult feeding behavior GO:0008343 7 7 0,000 4,269E-03 0,01368413 ! CoA carboxylase activity GO:0016421 7 7 0,000 4,269E-03 0,01367185 ! microtubule basal body GO:0005932 7 7 0,000 4,269E-03 0,0136596 ! positive regulation of NF-kappaB import into nucleus GO:0042346 7 7 0,000 4,269E-03 0,01364737 ! embryonic heart tube development GO:0035050 7 7 0,000 4,269E-03 0,01363517 ! kainate selective glutamate receptor activity GO:0015277 7 7 0,000 4,269E-03 0,01362298 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 4,269E-03 0,01361082 ! positive regulation of smooth muscle contraction GO:0045987 7 7 0,000 4,269E-03 0,01359868 ! rRNA transcription GO:0009303 8 8 0,000 4,877E-03 0,01552328 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 8 8 0,000 4,877E-03 0,01550946 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 4,877E-03 0,01549566 ! sodium:hydrogen antiporter activity GO:0015385 8 8 0,000 4,877E-03 0,01548188 GO:0005451|monovalent cation:hydrogen antiporter activity, ! negative regulation of lipid biosynthetic process GO:0051055 9 8 0,000 4,877E-03 0,01546813 ! cation:chloride symporter activity GO:0015377 9 8 0,000 4,877E-03 0,01545441 ! positive regulation of small GTPase mediated signal transduction GO:0051057 8 8 0,000 4,877E-03 0,01544071 GO:0046579|positive regulation of Ras protein signal transduction, ! forebrain neuron differentiation GO:0021879 9 8 0,000 4,877E-03 0,01542703 ! male meiosis GO:0007140 8 8 0,000 4,877E-03 0,01541338 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 8 8 0,000 4,877E-03 0,01539975 ! N-glycan processing GO:0006491 8 8 0,000 4,877E-03 0,01538615 ! regulation of smooth muscle cell migration GO:0014910 9 8 0,000 4,877E-03 0,01537257 ! protein self-association GO:0043621 8 8 0,000 4,877E-03 0,01535901 ! RNA methylation GO:0001510 8 8 0,000 4,877E-03 0,01534548 ! prostaglandin biosynthetic process GO:0001516 9 8 0,000 4,877E-03 0,01533197 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 8 8 0,000 4,877E-03 0,01531849 ! hexokinase activity GO:0004396 8 8 0,000 4,877E-03 0,01530503 ! neurofilament cytoskeleton GO:0060053 8 8 0,000 4,877E-03 0,01529159 ! guanylate cyclase activity GO:0004383 8 8 0,000 4,877E-03 0,01527817 ! integral to mitochondrial membrane GO:0032592 8 8 0,000 4,877E-03 0,01526478 ! troponin complex GO:0005861 9 8 0,000 4,877E-03 0,01525142 ! smoothened signaling pathway GO:0007224 8 8 0,000 4,877E-03 0,01523807 ! negative regulation of muscle cell differentiation GO:0051148 8 8 0,000 4,877E-03 0,01522475 ! ganglioside metabolic process GO:0001573 8 8 0,000 4,877E-03 0,01521146 ! reflex GO:0060004 11 8 0,000 4,877E-03 0,01519818 ! small protein activating enzyme activity GO:0008641 10 8 0,000 4,877E-03 0,01518493 ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 4,877E-03 0,01517171 ! hemoglobin metabolic process GO:0020027 8 8 0,000 4,877E-03 0,0151585 ! protein targeting to ER GO:0045047 9 8 0,000 4,877E-03 0,01514532 ! positive regulation of survival gene product expression GO:0045885 8 8 0,000 4,877E-03 0,01513216 ! arginine catabolic process GO:0006527 8 8 0,000 4,877E-03 0,01511903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 4,877E-03 0,01510591 ! malate dehydrogenase activity GO:0016615 8 8 0,000 4,877E-03 0,01509282 ! inner mitochondrial membrane organization GO:0007007 9 8 0,000 4,877E-03 0,01507976 ! telomere maintenance via telomerase GO:0007004 8 8 0,000 4,877E-03 0,01506671 GO:0010833|telomere maintenance via telomere lengthening, ! DNA secondary structure binding GO:0000217 8 8 0,000 4,877E-03 0,01505369 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 9 8 0,000 4,877E-03 0,01504069 ! proline metabolic process GO:0006560 9 8 0,000 4,877E-03 0,01502771 ! melanosome membrane GO:0033162 10 8 0,000 4,877E-03 0,01501476 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 4,877E-03 0,01500182 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 4,877E-03 0,01498891 ! melanin metabolic process GO:0006582 9 8 0,000 4,877E-03 0,01497603 ! death receptor activity GO:0005035 8 8 0,000 4,877E-03 0,01496316 ! Golgi lumen GO:0005796 8 8 0,000 4,877E-03 0,01495032 ! smooth endoplasmic reticulum GO:0005790 9 8 0,000 4,877E-03 0,01493749 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 4,877E-03 0,01492469 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 9 8 0,000 4,877E-03 0,01491192 GO:0048500|signal recognition particle, ! Golgi cisterna GO:0031985 9 8 0,000 4,877E-03 0,01489916 ! positive regulation of mesenchymal cell proliferation GO:0002053 8 8 0,000 4,877E-03 0,01488643 ! Rac protein signal transduction GO:0016601 8 8 0,000 4,877E-03 0,01487371 ! positive regulation of calcium ion transport into cytosol GO:0010524 11 8 0,000 4,877E-03 0,01486102 ! lens development in camera-type eye GO:0002088 8 8 0,000 4,877E-03 0,01484835 ! positive regulation of vasodilation GO:0045909 8 8 0,000 4,877E-03 0,01483571 ! intestinal cholesterol absorption GO:0030299 8 8 0,000 4,877E-03 0,01482308 ! negative regulation of muscle contraction GO:0045932 9 8 0,000 4,877E-03 0,01481047 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 8 8 0,000 4,877E-03 0,01479789 ! Schwann cell differentiation GO:0014037 8 8 0,000 4,877E-03 0,01478533 ! sodium:dicarboxylate symporter activity GO:0017153 8 8 0,000 4,877E-03 0,01477279 ! axon guidance receptor activity GO:0008046 8 8 0,000 4,877E-03 0,01476027 ! protein targeting to vacuole GO:0006623 8 8 0,000 4,877E-03 0,01474777 ! response to tropane GO:0014073 10 8 0,000 4,877E-03 0,01473529 GO:0042220|response to cocaine, ! purine nucleoside triphosphate catabolic process GO:0009146 8 8 0,000 4,877E-03 0,01472284 ! melanosome localization GO:0032400 8 8 0,000 4,877E-03 0,0147104 ! response to amine stimulus GO:0014075 10 8 0,000 4,877E-03 0,01469799 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 8 8 0,000 4,877E-03 0,0146856 ! sphingomyelin metabolic process GO:0006684 9 8 0,000 4,877E-03 0,01467323 ! regulation of mitochondrial membrane potential GO:0051881 8 8 0,000 4,877E-03 0,01466087 ! synaptic vesicle endocytosis GO:0048488 8 8 0,000 4,877E-03 0,01464854 ! holo TFIIH complex GO:0005675 8 8 0,000 4,877E-03 0,01463623 ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 4,877E-03 0,01462395 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 8 0,000 4,877E-03 0,01461168 ! negative regulation of cytokine secretion GO:0050710 8 8 0,000 4,877E-03 0,01459943 ! regulation of myoblast differentiation GO:0045661 8 8 0,000 4,877E-03 0,0145872 ! vitamin transporter activity GO:0051183 8 8 0,000 4,877E-03 0,01457499 ! positive regulation of erythrocyte differentiation GO:0045648 8 8 0,000 4,877E-03 0,01456281 ! neuromuscular process controlling posture GO:0050884 8 8 0,000 4,877E-03 0,01455064 ! heparan sulfate sulfotransferase activity GO:0034483 8 8 0,000 4,877E-03 0,0145385 ! regulation of epidermal cell differentiation GO:0045604 8 8 0,000 4,877E-03 0,01452637 ! regulation of T-helper 2 cell differentiation GO:0045628 8 8 0,000 4,877E-03 0,01451427 ! positive regulation of T-helper cell differentiation GO:0045624 8 8 0,000 4,877E-03 0,01450218 ! branched chain family amino acid catabolic process GO:0009083 8 8 0,000 4,877E-03 0,01449012 ! regulation of synaptogenesis GO:0051963 8 8 0,000 4,877E-03 0,01447807 ! oocyte differentiation GO:0009994 8 8 0,000 4,877E-03 0,01446605 GO:0048599|oocyte development, ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 8 8 0,000 4,877E-03 0,01445404 GO:0003756|protein disulfide isomerase activity, ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 4,877E-03 0,01444206 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 8 0,000 4,877E-03 0,01443009 ! beta-1,3-galactosyltransferase activity GO:0048531 8 8 0,000 4,877E-03 0,01441814 ! establishment of pigment granule localization GO:0051905 8 8 0,000 4,877E-03 0,01440622 ! regulation of telomere maintenance GO:0032204 8 8 0,000 4,877E-03 0,01439431 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 4,877E-03 0,01438243 ! amino sugar catabolic process GO:0046348 8 8 0,000 4,877E-03 0,01437056 GO:0006043|glucosamine catabolic process, ! regulation of amino acid transport GO:0051955 8 8 0,000 4,877E-03 0,01435871 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 4,877E-03 0,01434689 ! T cell receptor signaling pathway GO:0050852 13 8 0,000 4,877E-03 0,01433508 ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 8 0,000 4,877E-03 0,01432329 ! cholesterol transporter activity GO:0017127 8 8 0,000 4,877E-03 0,01431152 ! GABA receptor binding GO:0050811 8 8 0,000 4,877E-03 0,01429977 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 8 8 0,000 4,877E-03 0,01428804 ! regulation of microtubule polymerization GO:0031113 8 8 0,000 4,877E-03 0,01427633 ! regulation of developmental growth GO:0048638 8 8 0,000 4,877E-03 0,01426463 ! GMP binding GO:0019002 10 8 0,000 4,877E-03 0,01425296 GO:0030553|cGMP binding, ! regulation of epithelial cell differentiation GO:0030856 8 8 0,000 4,877E-03 0,01424131 ! negative regulation of cellular catabolic process GO:0031330 9 8 0,000 4,877E-03 0,01422967 ! prostate gland development GO:0030850 8 8 0,000 4,877E-03 0,01421806 ! 7S RNA binding GO:0008312 9 8 0,000 4,877E-03 0,01420646 ! phosphate transport GO:0006817 9 8 0,000 4,877E-03 0,01419488 ! neutral lipid catabolic process GO:0046461 8 8 0,000 4,877E-03 0,01418332 ! protein phosphorylated amino acid binding GO:0045309 10 8 0,000 4,877E-03 0,01417178 ! reproductive behavior GO:0019098 8 8 0,000 4,877E-03 0,01416026 ! cell volume homeostasis GO:0006884 9 8 0,000 4,877E-03 0,01414876 ! regulation of long-term neuronal synaptic plasticity GO:0048169 8 8 0,000 4,877E-03 0,01413727 ! oligopeptide transport GO:0006857 8 8 0,000 4,877E-03 0,01412581 GO:0015198|oligopeptide transporter activity, ! induction of positive chemotaxis GO:0050930 8 8 0,000 4,877E-03 0,01411436 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 4,877E-03 0,01410293 ! regulation of dopamine metabolic process GO:0042053 8 8 0,000 4,877E-03 0,01409152 GO:0042069|regulation of catecholamine metabolic process, ! regulation of carbohydrate biosynthetic process GO:0043255 8 8 0,000 4,877E-03 0,01408013 ! titin binding GO:0031432 8 8 0,000 4,877E-03 0,01406875 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 4,877E-03 0,0140574 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 8 0,000 4,877E-03 0,01404606 ! bone resorption GO:0045453 8 8 0,000 4,877E-03 0,01403474 ! glycerolipid catabolic process GO:0046503 8 8 0,000 4,877E-03 0,01402344 ! endoderm development GO:0007492 8 8 0,000 4,877E-03 0,01401216 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 4,877E-03 0,0140009 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 4,877E-03 0,01398965 ! astrocyte differentiation GO:0048708 8 8 0,000 4,877E-03 0,01397843 ! embryonic cranial skeleton morphogenesis GO:0048701 8 8 0,000 4,877E-03 0,01396722 ! syncytium formation GO:0006949 8 8 0,000 4,877E-03 0,01395602 ! B cell proliferation GO:0042100 8 8 0,000 4,877E-03 0,01394485 ! mannose metabolic process GO:0006013 10 8 0,000 4,877E-03 0,01393369 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 8 8 0,000 4,877E-03 0,01392256 ! asymmetric protein localization GO:0008105 8 8 0,000 4,877E-03 0,01391144 ! tumor necrosis factor binding GO:0043120 8 8 0,000 4,877E-03 0,01390033 ! synaptic transmission, glutamatergic GO:0035249 9 8 0,000 4,877E-03 0,01388925 ! macroautophagy GO:0016236 9 8 0,000 4,877E-03 0,01387818 ! Cajal body GO:0015030 8 8 0,000 4,877E-03 0,01386713 ! O-methyltransferase activity GO:0008171 9 8 0,000 4,877E-03 0,0138561 ! H4/H2A histone acetyltransferase complex GO:0043189 9 8 0,000 4,877E-03 0,01384509 ! PcG protein complex GO:0031519 8 8 0,000 4,877E-03 0,01383409 ! ferric iron binding GO:0008199 9 8 0,000 4,877E-03 0,01382311 ! spindle checkpoint GO:0031577 8 8 0,000 4,877E-03 0,01381215 ! G1 DNA damage checkpoint GO:0031571 8 8 0,000 4,877E-03 0,0138012 ! segment specification GO:0007379 8 8 0,000 4,877E-03 0,01379028 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 4,877E-03 0,01377937 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 4,877E-03 0,01376847 ! cellular extravasation GO:0045123 9 8 0,000 4,877E-03 0,0137576 ! pronucleus GO:0045120 8 8 0,000 4,877E-03 0,01374674 ! regulation of insulin receptor signaling pathway GO:0046626 8 8 0,000 4,877E-03 0,0137359 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 8 8 0,000 4,877E-03 0,01372507 ! Rac GTPase activator activity GO:0030675 9 8 0,000 4,877E-03 0,01371427 ! regulation of DNA repair GO:0006282 8 8 0,000 4,877E-03 0,01370348 ! transcription-coupled nucleotide-excision repair GO:0006283 9 8 0,000 4,877E-03 0,0136927 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 4,877E-03 0,01368195 ! antigen processing and presentation of exogenous antigen GO:0019884 9 8 0,000 4,877E-03 0,01367121 ! DNA ligation GO:0006266 8 8 0,000 4,877E-03 0,01366049 ! regulation of T cell differentiation in the thymus GO:0033081 8 8 0,000 4,877E-03 0,01364978 ! negative regulation of systemic arterial blood pressure GO:0003085 8 8 0,000 4,877E-03 0,01363909 ! multicellular organismal aging GO:0010259 8 8 0,000 4,877E-03 0,01362842 ! erythrocyte development GO:0048821 8 8 0,000 4,877E-03 0,01361776 ! interleukin-1 receptor activity GO:0004908 8 8 0,000 4,877E-03 0,01360712 ! positive regulation of monooxygenase activity GO:0032770 8 8 0,000 4,877E-03 0,0135965 ! protein import into peroxisome matrix GO:0016558 8 8 0,000 4,877E-03 0,0135859 ! gamma-tubulin binding GO:0043015 8 8 0,000 4,877E-03 0,01357531 ! ribosome binding GO:0043022 9 8 0,000 4,877E-03 0,01356473 ! mRNA polyadenylation GO:0006378 8 8 0,000 4,877E-03 0,01355418 ! sodium:amino acid symporter activity GO:0005283 8 8 0,000 4,877E-03 0,01354364 ! adenylyltransferase activity GO:0070566 8 8 0,000 4,877E-03 0,01353311 ! zymogen activation GO:0031638 8 8 0,000 4,877E-03 0,01352261 ! axonal fasciculation GO:0007413 8 8 0,000 4,877E-03 0,01351212 ! negative regulation of nuclear division GO:0051784 8 8 0,000 4,877E-03 0,01350164 GO:0045839|negative regulation of mitosis, ! caspase inhibitor activity GO:0043027 8 8 0,000 4,877E-03 0,01349118 ! energy coupled proton transport, against electrochemical gradient GO:0015988 8 8 0,000 4,877E-03 0,01348074 GO:0015991|ATP hydrolysis coupled proton transport, ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 8 8 0,000 4,877E-03 0,01347032 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 4,877E-03 0,01345991 ! thyroid hormone receptor activity GO:0004887 8 8 0,000 4,877E-03 0,01344951 ! wide pore channel activity GO:0022829 8 8 0,000 4,877E-03 0,01343913 ! ligand-regulated transcription factor activity GO:0003706 8 8 0,000 4,877E-03 0,01342877 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 4,877E-03 0,01341843 ! hormone catabolic process GO:0042447 8 8 0,000 4,877E-03 0,0134081 ! positive regulation of ATPase activity GO:0032781 8 8 0,000 4,877E-03 0,01339778 ! biogenic amine catabolic process GO:0042402 11 8 0,000 4,877E-03 0,01338749 ! Notch binding GO:0005112 8 8 0,000 4,877E-03 0,0133772 ! death receptor binding GO:0005123 8 8 0,000 4,877E-03 0,01336694 ! ATPase regulator activity GO:0060590 8 8 0,000 4,877E-03 0,01335669 ! pyrimidine base metabolic process GO:0006206 10 8 0,000 4,877E-03 0,01334645 ! epidermal growth factor receptor binding GO:0005154 9 8 0,000 4,877E-03 0,01333623 ! dihydropyridine-sensitive calcium channel activity GO:0015270 8 8 0,000 4,877E-03 0,01332603 ! calcium-release channel activity GO:0015278 8 8 0,000 4,877E-03 0,01331584 ! tubulin-tyrosine ligase activity GO:0004835 8 8 0,000 4,877E-03 0,01330567 ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 4,877E-03 0,01329551 ! nucleus localization GO:0051647 10 8 0,000 4,877E-03 0,01328537 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 4,877E-03 0,01327524 ! negative regulation of immune effector process GO:0002698 12 8 0,000 4,877E-03 0,01326513 ! adenosine deaminase activity GO:0004000 8 8 0,000 4,877E-03 0,01325504 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 9 9 0,000 5,486E-03 0,01489653 ! telencephalon cell migration GO:0022029 9 9 0,000 5,486E-03 0,01488521 ! 'de novo' posttranslational protein folding GO:0051084 9 9 0,000 5,486E-03 0,01487391 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 5,486E-03 0,01486263 ! cGMP metabolic process GO:0046068 9 9 0,000 5,486E-03 0,01485136 GO:0006182|cGMP biosynthetic process, ! regulation of epidermal growth factor receptor activity GO:0007176 9 9 0,000 5,486E-03 0,01484011 GO:0010469|regulation of receptor activity, ! inositol trisphosphate phosphatase activity GO:0046030 11 9 0,000 5,486E-03 0,01482887 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! axon part GO:0033267 12 9 0,000 5,486E-03 0,01481766 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 9 9 0,000 5,486E-03 0,01480646 ! RNA polyadenylation GO:0043631 9 9 0,000 5,486E-03 0,01479527 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 9 0,000 5,486E-03 0,01478411 ! regulation of receptor-mediated endocytosis GO:0048259 9 9 0,000 5,486E-03 0,01477296 ! artery development GO:0060840 9 9 0,000 5,486E-03 0,01476182 GO:0048844|artery morphogenesis, ! photoreceptor cell development GO:0042461 12 9 0,000 5,486E-03 0,01475071 GO:0046530|photoreceptor cell differentiation, ! microtubule bundle formation GO:0001578 9 9 0,000 5,486E-03 0,01473961 ! middle ear morphogenesis GO:0042474 9 9 0,000 5,486E-03 0,01472853 ! regulation of mesenchymal cell proliferation GO:0010464 9 9 0,000 5,486E-03 0,01471746 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 12 9 0,000 5,486E-03 0,01470641 GO:0046330|positive regulation of JNK cascade, ! positive regulation of heart contraction GO:0045823 10 9 0,000 5,486E-03 0,01469538 ! lung alveolus development GO:0048286 9 9 0,000 5,486E-03 0,01468436 ! ciliary or flagellar motility GO:0001539 9 9 0,000 5,486E-03 0,01467336 ! beta-amyloid binding GO:0001540 10 9 0,000 5,486E-03 0,01466238 ! pathogenesis GO:0009405 9 9 0,000 5,486E-03 0,01465141 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 10 9 0,000 5,486E-03 0,01464046 ! regulated secretory pathway GO:0045055 9 9 0,000 5,486E-03 0,01462953 ! regulation of S phase of mitotic cell cycle GO:0007090 9 9 0,000 5,486E-03 0,01461861 ! estrogen receptor binding GO:0030331 9 9 0,000 5,486E-03 0,01460771 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 10 9 0,000 5,486E-03 0,01459683 ! regulation of defense response to virus by virus GO:0050690 9 9 0,000 5,486E-03 0,01458596 ! histidine metabolic process GO:0006547 9 9 0,000 5,486E-03 0,0145751 GO:0009075|histidine family amino acid metabolic process, ! L-phenylalanine metabolic process GO:0006558 10 9 0,000 5,486E-03 0,01456427 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 9 9 0,000 5,486E-03 0,01455345 GO:0005978|glycogen biosynthetic process, ! V(D)J recombination GO:0033151 9 9 0,000 5,486E-03 0,01454264 ! nucleobase biosynthetic process GO:0046112 11 9 0,000 5,486E-03 0,01453185 ! regulation of Cdc42 protein signal transduction GO:0032489 9 9 0,000 5,486E-03 0,01452108 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of calcium ion transport into cytosol GO:0010522 12 9 0,000 5,486E-03 0,01451033 ! entry into host cell GO:0030260 9 9 0,000 5,486E-03 0,01449959 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 9 9 0,000 5,486E-03 0,01448886 ! regulation of lipoprotein lipase activity GO:0051004 9 9 0,000 5,486E-03 0,01447815 ! retinoic acid metabolic process GO:0042573 9 9 0,000 5,486E-03 0,01446746 ! retinol metabolic process GO:0042572 9 9 0,000 5,486E-03 0,01445678 ! behavioral fear response GO:0001662 9 9 0,000 5,486E-03 0,01444612 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 10 9 0,000 5,486E-03 0,01443548 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 9 9 0,000 5,486E-03 0,01442485 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! motor axon guidance GO:0008045 9 9 0,000 5,486E-03 0,01441423 ! regulation of gliogenesis GO:0014013 9 9 0,000 5,486E-03 0,01440363 GO:0045685|regulation of glial cell differentiation, ! recycling endosome membrane GO:0055038 10 9 0,000 5,486E-03 0,01439305 ! pigment granule localization GO:0051875 9 9 0,000 5,486E-03 0,01438248 ! platelet-derived growth factor binding GO:0048407 10 9 0,000 5,486E-03 0,01437193 ! glycosphingolipid biosynthetic process GO:0006688 9 9 0,000 5,486E-03 0,01436139 ! nucleoside diphosphate metabolic process GO:0009132 10 9 0,000 5,486E-03 0,01435087 ! phosphoinositide 3-kinase cascade GO:0014065 9 9 0,000 5,486E-03 0,01434037 ! cell wall macromolecule catabolic process GO:0016998 10 9 0,000 5,486E-03 0,01432988 ! purine ribonucleotide catabolic process GO:0009154 9 9 0,000 5,486E-03 0,0143194 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 9 9 0,000 5,486E-03 0,01430894 ! positive regulation of Rho GTPase activity GO:0032321 9 9 0,000 5,486E-03 0,0142985 ! nitric oxide metabolic process GO:0046209 9 9 0,000 5,486E-03 0,01428807 GO:0006809|nitric oxide biosynthetic process, ! mismatch repair complex GO:0032300 9 9 0,000 5,486E-03 0,01427765 ! icosanoid secretion GO:0032309 9 9 0,000 5,486E-03 0,01426725 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 10 9 0,000 5,486E-03 0,01425687 GO:0010092|specification of organ identity, ! retinal ganglion cell axon guidance GO:0031290 9 9 0,000 5,486E-03 0,0142465 ! morphogenesis of a polarized epithelium GO:0001738 9 9 0,000 5,486E-03 0,01423615 ! sterol catabolic process GO:0016127 9 9 0,000 5,486E-03 0,01422581 GO:0006707|cholesterol catabolic process, ! prophase GO:0051324 9 9 0,000 5,486E-03 0,01421549 ! peptidyl-lysine modification GO:0018205 9 9 0,000 5,486E-03 0,01420518 ! pancreatic ribonuclease activity GO:0004522 9 9 0,000 5,486E-03 0,01419488 ! clathrin coat of coated pit GO:0030132 12 9 0,000 5,486E-03 0,01418461 ! SNARE complex GO:0031201 10 9 0,000 5,486E-03 0,01417434 ! ubiquinone metabolic process GO:0006743 10 9 0,000 5,486E-03 0,01416409 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! snRNA binding GO:0017069 9 9 0,000 5,486E-03 0,01415386 ! regulation of macrophage differentiation GO:0045649 9 9 0,000 5,486E-03 0,01414364 ! regulation of osteoclast differentiation GO:0045670 10 9 0,000 5,486E-03 0,01413343 ! positive regulation of neuron differentiation GO:0045666 9 9 0,000 5,486E-03 0,01412324 ! negative regulation of lymphocyte differentiation GO:0045620 9 9 0,000 5,486E-03 0,01411307 ! methionine biosynthetic process GO:0009086 10 9 0,000 5,486E-03 0,01410291 ! peptidoglycan binding GO:0042834 9 9 0,000 5,486E-03 0,01409276 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 5,486E-03 0,01408263 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! pyridine nucleotide biosynthetic process GO:0019363 9 9 0,000 5,486E-03 0,01407251 ! intramolecular transferase activity, phosphotransferases GO:0016868 9 9 0,000 5,486E-03 0,01406241 ! cholesterol efflux GO:0033344 9 9 0,000 5,486E-03 0,01405232 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 9 9 0,000 5,486E-03 0,01404225 ! metalloenzyme inhibitor activity GO:0048551 10 9 0,000 5,486E-03 0,01403219 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! leukocyte mediated cytotoxicity GO:0001909 9 9 0,000 5,486E-03 0,01402215 ! anterior/posterior axis specification GO:0009948 9 9 0,000 5,486E-03 0,01401212 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 5,486E-03 0,0140021 ! detection of calcium ion GO:0005513 10 9 0,000 5,486E-03 0,0139921 ! negative regulation of glucose import GO:0046325 9 9 0,000 5,486E-03 0,01398211 GO:0010829|negative regulation of glucose transport, ! regulation of fibrinolysis GO:0051917 9 9 0,000 5,486E-03 0,01397214 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 9 0,000 5,486E-03 0,01396218 ! hydrolase activity, acting on ether bonds GO:0016801 9 9 0,000 5,486E-03 0,01395224 ! desmosome GO:0030057 9 9 0,000 5,486E-03 0,01394231 ! prepulse inhibition GO:0060134 9 9 0,000 5,486E-03 0,01393239 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 9 0,000 5,486E-03 0,01392249 ! anchoring collagen GO:0030934 9 9 0,000 5,486E-03 0,0139126 ! axon extension GO:0048675 10 9 0,000 5,486E-03 0,01390273 ! neuron fate specification GO:0048665 9 9 0,000 5,486E-03 0,01389287 ! positive regulation of glucose metabolic process GO:0010907 9 9 0,000 5,486E-03 0,01388302 ! cortical actin cytoskeleton organization GO:0030866 9 9 0,000 5,486E-03 0,01387319 ! virus-host interaction GO:0019048 13 9 0,000 5,486E-03 0,01386337 ! rough endoplasmic reticulum membrane GO:0030867 9 9 0,000 5,486E-03 0,01385356 ! pentose-phosphate shunt GO:0006098 9 9 0,000 5,486E-03 0,01384377 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 5,486E-03 0,013834 ! DNA bending activity GO:0008301 9 9 0,000 5,486E-03 0,01382423 ! social behavior GO:0035176 9 9 0,000 5,486E-03 0,01381449 ! secondary active sulfate transmembrane transporter activity GO:0008271 9 9 0,000 5,486E-03 0,01380475 ! dipeptidyl-peptidase activity GO:0008239 11 9 0,000 5,486E-03 0,01379503 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 5,486E-03 0,01378532 ! very-low-density lipoprotein particle GO:0034361 9 9 0,000 5,486E-03 0,01377563 GO:0034385|triglyceride-rich lipoprotein particle, ! high-density lipoprotein particle GO:0034364 9 9 0,000 5,486E-03 0,01376595 ! amyloid precursor protein metabolic process GO:0042982 10 9 0,000 5,486E-03 0,01375628 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 11 9 0,000 5,486E-03 0,01374662 ! blood vessel remodeling GO:0001974 10 9 0,000 5,486E-03 0,01373698 ! 3'-5'-exoribonuclease activity GO:0000175 9 9 0,000 5,486E-03 0,01372736 ! exosome (RNase complex) GO:0000178 9 9 0,000 5,486E-03 0,01371775 ! inositol phosphate-mediated signaling GO:0048016 9 9 0,000 5,486E-03 0,01370815 ! DNA N-glycosylase activity GO:0019104 9 9 0,000 5,486E-03 0,01369856 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 9 9 0,000 5,486E-03 0,01368899 GO:0033549|MAP kinase phosphatase activity, ! ER overload response GO:0006983 11 9 0,000 5,486E-03 0,01367943 ! zinc ion transmembrane transporter activity GO:0005385 9 9 0,000 5,486E-03 0,01366988 ! glucose transmembrane transporter activity GO:0005355 9 9 0,000 5,486E-03 0,01366035 ! retrograde transport, endosome to Golgi GO:0042147 10 9 0,000 5,486E-03 0,01365083 ! phagocytosis, engulfment GO:0006911 10 9 0,000 5,486E-03 0,01364132 ! neurotransmitter biosynthetic process GO:0042136 10 9 0,000 5,486E-03 0,01363183 ! carbohydrate phosphatase activity GO:0019203 9 9 0,000 5,486E-03 0,01362235 ! glutathione peroxidase activity GO:0004602 9 9 0,000 5,486E-03 0,01361288 ! acyl-CoA thioesterase activity GO:0016291 9 9 0,000 5,486E-03 0,01360343 ! lysophospholipase activity GO:0004622 9 9 0,000 5,486E-03 0,01359399 ! brain morphogenesis GO:0048854 9 9 0,000 5,486E-03 0,01358456 ! apolipoprotein binding GO:0034185 9 9 0,000 5,486E-03 0,01357515 ! synaptic vesicle membrane GO:0030672 9 9 0,000 5,486E-03 0,01356575 ! RNA-dependent DNA replication GO:0006278 9 9 0,000 5,486E-03 0,01355636 ! positive regulation of systemic arterial blood pressure GO:0003084 10 9 0,000 5,486E-03 0,01354698 ! kinesin binding GO:0019894 9 9 0,000 5,486E-03 0,01353762 ! nucleoside bisphosphate metabolic process GO:0033865 10 9 0,000 5,486E-03 0,01352827 ! renal water homeostasis GO:0003091 9 9 0,000 5,486E-03 0,01351894 ! positive regulation of interleukin-6 production GO:0032755 9 9 0,000 5,486E-03 0,01350961 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 5,486E-03 0,0135003 ! histone methylation GO:0016571 10 9 0,000 5,486E-03 0,01349101 ! mRNA cleavage GO:0006379 9 9 0,000 5,486E-03 0,01348172 ! negative regulation of tumor necrosis factor production GO:0032720 9 9 0,000 5,486E-03 0,01347245 ! regulation of transcription from RNA polymerase III promoter GO:0006359 9 9 0,000 5,486E-03 0,01346319 ! sarcoplasmic reticulum membrane GO:0033017 10 9 0,000 5,486E-03 0,01345394 ! opioid receptor activity GO:0004985 9 9 0,000 5,486E-03 0,01344471 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 5,486E-03 0,01343549 ! salivary gland development GO:0007431 10 9 0,000 5,486E-03 0,01342628 ! glucosidase activity GO:0015926 10 9 0,000 5,486E-03 0,01341708 ! adrenoceptor activity GO:0004935 11 9 0,000 5,486E-03 0,0134079 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 9 9 0,000 5,486E-03 0,01339873 ! positive regulation of leukocyte migration GO:0002687 9 9 0,000 5,486E-03 0,01338957 ! purine base metabolic process GO:0006144 11 9 0,000 5,486E-03 0,01338042 ! mRNA 3'-UTR binding GO:0003730 9 9 0,000 5,486E-03 0,01337129 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 9 9 0,000 5,486E-03 0,01336217 ! receptor inhibitor activity GO:0030547 9 9 0,000 5,486E-03 0,01335306 GO:0048019|receptor antagonist activity, ! negative regulation of BMP signaling pathway GO:0030514 9 9 0,000 5,486E-03 0,01334396 ! ionotropic glutamate receptor complex GO:0008328 11 9 0,000 5,486E-03 0,01333488 ! transforming growth factor beta receptor binding GO:0005160 9 9 0,000 5,486E-03 0,01332581 ! palmitoyltransferase activity GO:0016409 9 9 0,000 5,486E-03 0,01331675 ! arylsulfatase activity GO:0004065 9 9 0,000 5,486E-03 0,0133077 ! phospholipase inhibitor activity GO:0004859 9 9 0,000 5,486E-03 0,01329867 ! behavioral response to nicotine GO:0035095 9 9 0,000 5,486E-03 0,01328965 ! adenylate kinase activity GO:0004017 10 9 0,000 5,486E-03 0,01328064 ! alcohol dehydrogenase (NAD) activity GO:0004022 9 9 0,000 5,486E-03 0,01327164 ! mitochondrion localization GO:0051646 9 9 0,000 5,486E-03 0,01326265 ! localization within membrane GO:0051668 9 9 0,000 5,486E-03 0,01325368 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 10 0,000 6,093E-03 0,01471236 ! lipid particle GO:0005811 10 10 0,000 6,093E-03 0,01470242 ! myotube differentiation GO:0014902 10 10 0,000 6,093E-03 0,01469249 ! generation of neurons in the forebrain GO:0021872 11 10 0,000 6,093E-03 0,01468258 ! regulation of cellular amine metabolic process GO:0033238 10 10 0,000 6,093E-03 0,01467268 ! synapsis GO:0007129 10 10 0,000 6,093E-03 0,01466279 GO:0070192|chromosome organization involved in meiosis, ! filopodium assembly GO:0046847 12 10 0,000 6,093E-03 0,01465292 ! UTP metabolic process GO:0046051 10 10 0,000 6,093E-03 0,01464306 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 10 10 0,000 6,093E-03 0,01463321 ! COPI coating of Golgi vesicle GO:0048205 10 10 0,000 6,093E-03 0,01462337 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 10 10 0,000 6,093E-03 0,01461355 ! platelet alpha granule membrane GO:0031092 11 10 0,000 6,093E-03 0,01460375 ! macromolecule transmembrane transporter activity GO:0022884 10 10 0,000 6,093E-03 0,01459395 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! lipoprotein receptor binding GO:0070325 10 10 0,000 6,093E-03 0,01458417 GO:0050750|low-density lipoprotein receptor binding, ! thyroid hormone receptor coactivator activity GO:0030375 10 10 0,000 6,093E-03 0,0145744 GO:0010861|thyroid hormone receptor activator activity, ! auditory receptor cell differentiation GO:0042491 11 10 0,000 6,093E-03 0,01456465 ! regulation of chemokine biosynthetic process GO:0045073 10 10 0,000 6,093E-03 0,0145549 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 10 10 0,000 6,093E-03 0,01454518 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 10 10 0,000 6,093E-03 0,01453546 ! nucleotide-sugar metabolic process GO:0009225 11 10 0,000 6,093E-03 0,01452576 ! regulation of catecholamine secretion GO:0050433 10 10 0,000 6,093E-03 0,01451607 ! melanocyte differentiation GO:0030318 10 10 0,000 6,093E-03 0,01450639 GO:0050931|pigment cell differentiation, ! deoxyribonucleotide catabolic process GO:0009264 10 10 0,000 6,093E-03 0,01449672 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 10 10 0,000 6,093E-03 0,01448707 ! lipase inhibitor activity GO:0055102 10 10 0,000 6,093E-03 0,01447743 ! autophagic vacuole GO:0005776 11 10 0,000 6,093E-03 0,01446781 ! NAD metabolic process GO:0019674 10 10 0,000 6,093E-03 0,01445819 ! stereocilium GO:0032420 10 10 0,000 6,093E-03 0,01444859 GO:0032421|stereocilium bundle, ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 6,093E-03 0,01443901 ! regulation of sodium ion transport GO:0002028 10 10 0,000 6,093E-03 0,01442943 ! forebrain cell migration GO:0021885 10 10 0,000 6,093E-03 0,01441987 ! organelle subcompartment GO:0031984 11 10 0,000 6,093E-03 0,01441032 ! chondrocyte differentiation GO:0002062 10 10 0,000 6,093E-03 0,01440078 ! negative regulation of ossification GO:0030279 10 10 0,000 6,093E-03 0,01439126 ! regulation of smoothened signaling pathway GO:0008589 10 10 0,000 6,093E-03 0,01438175 ! heparan sulfate proteoglycan metabolic process GO:0030201 10 10 0,000 6,093E-03 0,01437225 ! phosphatidylcholine biosynthetic process GO:0006656 12 10 0,000 6,093E-03 0,01436276 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 10 10 0,000 6,093E-03 0,01435329 ! protein homotetramerization GO:0051289 11 10 0,000 6,093E-03 0,01434382 ! regulation of dephosphorylation GO:0035303 12 10 0,000 6,093E-03 0,01433438 ! oligodendrocyte development GO:0014003 10 10 0,000 6,093E-03 0,01432494 ! positive regulation of phagocytosis GO:0050766 10 10 0,000 6,093E-03 0,01431551 ! response to dsRNA GO:0043331 10 10 0,000 6,093E-03 0,0143061 ! snRNA metabolic process GO:0016073 10 10 0,000 6,093E-03 0,0142967 GO:0016180|snRNA processing, ! cranial nerve development GO:0021545 10 10 0,000 6,093E-03 0,01428732 ! fucose catabolic process GO:0019317 11 10 0,000 6,093E-03 0,01427794 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 10 10 0,000 6,093E-03 0,01426858 ! retinal binding GO:0016918 10 10 0,000 6,093E-03 0,01425923 ! leukocyte activation during immune response GO:0002366 10 10 0,000 6,093E-03 0,01424989 GO:0002263|cell activation during immune response, ! cerebellum morphogenesis GO:0021587 11 10 0,000 6,093E-03 0,01424056 GO:0021696|cerebellar cortex morphogenesis, ! photoreceptor outer segment GO:0001750 10 10 0,000 6,093E-03 0,01423125 ! negative regulation of MAPKKK cascade GO:0043409 10 10 0,000 6,093E-03 0,01422195 ! regulation of T-helper 2 type immune response GO:0002828 10 10 0,000 6,093E-03 0,01421266 ! ribonuclease P activity GO:0004526 10 10 0,000 6,093E-03 0,01420338 ! midbrain development GO:0030901 10 10 0,000 6,093E-03 0,01419412 ! musculoskeletal movement GO:0050881 10 10 0,000 6,093E-03 0,01418486 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 10 10 0,000 6,093E-03 0,01417562 ! regulation of T-helper cell differentiation GO:0045622 10 10 0,000 6,093E-03 0,01416639 ! fatty-acid ligase activity GO:0015645 10 10 0,000 6,093E-03 0,01415718 GO:0004467|long-chain-fatty-acid-CoA ligase activity, ! regulation of mRNA stability GO:0043488 10 10 0,000 6,093E-03 0,01414797 ! quaternary ammonium group transport GO:0015697 10 10 0,000 6,093E-03 0,01413878 ! regulation of RNA splicing GO:0043484 10 10 0,000 6,093E-03 0,0141296 ! embryonic gut development GO:0048566 10 10 0,000 6,093E-03 0,01412043 ! positive regulation of amine transport GO:0051954 10 10 0,000 6,093E-03 0,01411127 ! defense response to Gram-positive bacterium GO:0050830 10 10 0,000 6,093E-03 0,01410213 ! mRNA 3'-end processing GO:0031124 10 10 0,000 6,093E-03 0,01409299 ! lysogeny GO:0030069 10 10 0,000 6,093E-03 0,01408387 GO:0019047|provirus integration, ! lamellipodium assembly GO:0030032 11 10 0,000 6,093E-03 0,01407476 ! establishment of cell polarity GO:0030010 10 10 0,000 6,093E-03 0,01406566 ! regulation of synapse organization GO:0050807 10 10 0,000 6,093E-03 0,01405658 ! cell wall macromolecule metabolic process GO:0044036 11 10 0,000 6,093E-03 0,0140475 ! acyl-CoA binding GO:0000062 10 10 0,000 6,093E-03 0,01403844 ! negative regulation of muscle development GO:0048635 11 10 0,000 6,093E-03 0,01402939 GO:0045843|negative regulation of striated muscle development, ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 6,093E-03 0,01402035 ! GDP binding GO:0019003 10 10 0,000 6,093E-03 0,01401132 ! photoreceptor activity GO:0009881 10 10 0,000 6,093E-03 0,0140023 ! somatic diversification of immune receptors via somatic mutation GO:0002566 10 10 0,000 6,093E-03 0,0139933 GO:0016446|somatic hypermutation of immunoglobulin genes, ! cortical cytoskeleton organization GO:0030865 10 10 0,000 6,093E-03 0,01398431 ! nitric-oxide synthase binding GO:0050998 11 10 0,000 6,093E-03 0,01397533 ! nuclear chromosome, telomeric region GO:0000784 10 10 0,000 6,093E-03 0,01396636 ! nucleotidase activity GO:0008252 10 10 0,000 6,093E-03 0,0139574 ! detection of mechanical stimulus GO:0050982 10 10 0,000 6,093E-03 0,01394845 ! protein complex disassembly GO:0043241 11 10 0,000 6,093E-03 0,01393951 GO:0043624|cellular protein complex disassembly, ! androgen metabolic process GO:0008209 10 10 0,000 6,093E-03 0,01393059 ! lateral plasma membrane GO:0016328 10 10 0,000 6,093E-03 0,01392168 ! estrogen metabolic process GO:0008210 10 10 0,000 6,093E-03 0,01391278 ! nucleocytoplasmic transporter activity GO:0005487 10 10 0,000 6,093E-03 0,01390389 ! retinol dehydrogenase activity GO:0004745 10 10 0,000 6,093E-03 0,01389501 ! negative regulation of cell-matrix adhesion GO:0001953 12 10 0,000 6,093E-03 0,01388614 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 11 10 0,000 6,093E-03 0,01387728 ! interleukin-1 binding GO:0019966 10 10 0,000 6,093E-03 0,01386844 ! endothelial cell differentiation GO:0045446 10 10 0,000 6,093E-03 0,01385961 ! cullin-RING ubiquitin ligase complex GO:0031461 10 10 0,000 6,093E-03 0,01385078 ! acid phosphatase activity GO:0003993 10 10 0,000 6,093E-03 0,01384197 ! regulation of stress fiber formation GO:0051492 13 10 0,000 6,093E-03 0,01383317 ! sodium:potassium-exchanging ATPase activity GO:0005391 11 10 0,000 6,093E-03 0,01382438 ! calcium-transporting ATPase activity GO:0005388 12 10 0,000 6,093E-03 0,01381561 ! telomeric DNA binding GO:0042162 11 10 0,000 6,093E-03 0,01380684 ! lipid digestion GO:0044241 10 10 0,000 6,093E-03 0,01379809 ! multicellular organism growth GO:0035264 10 10 0,000 6,093E-03 0,01378934 ! receptor clustering GO:0043113 10 10 0,000 6,093E-03 0,01378061 ! L-glutamate transmembrane transporter activity GO:0005313 10 10 0,000 6,093E-03 0,01377189 GO:0015172|acidic amino acid transmembrane transporter activity, ! brush border membrane GO:0031526 11 10 0,000 6,093E-03 0,01376318 ! adult heart development GO:0007512 12 10 0,000 6,093E-03 0,01375448 ! actin cytoskeleton reorganization GO:0031532 12 10 0,000 6,093E-03 0,01374579 ! signalosome GO:0008180 10 10 0,000 6,093E-03 0,01373711 ! prefoldin complex GO:0016272 10 10 0,000 6,093E-03 0,01372844 ! neuromuscular junction GO:0031594 10 10 0,000 6,093E-03 0,01371979 ! regulation of bone resorption GO:0045124 11 10 0,000 6,093E-03 0,01371114 ! positive regulation of peptide secretion GO:0002793 10 10 0,000 6,093E-03 0,01370251 ! alpha-beta T cell differentiation GO:0046632 11 10 0,000 6,093E-03 0,01369388 ! negative regulation of myeloid leukocyte differentiation GO:0002762 10 10 0,000 6,093E-03 0,01368527 ! positive regulation of T cell mediated immunity GO:0002711 14 10 0,000 6,093E-03 0,01367667 ! taste receptor activity GO:0008527 10 10 0,000 6,093E-03 0,01366808 ! Ran GTPase binding GO:0008536 10 10 0,000 6,093E-03 0,0136595 ! endocytic vesicle membrane GO:0030666 10 10 0,000 6,093E-03 0,01365093 ! regulation of interleukin-12 production GO:0032655 10 10 0,000 6,093E-03 0,01364237 ! ribosome assembly GO:0042255 10 10 0,000 6,093E-03 0,01363382 ! DNA methylation GO:0006306 12 10 0,000 6,093E-03 0,01362529 GO:0006305|DNA alkylation, ! protein-hormone receptor activity GO:0016500 10 10 0,000 6,093E-03 0,01361676 ! bile acid transmembrane transporter activity GO:0015125 10 10 0,000 6,093E-03 0,01360824 ! proteasome accessory complex GO:0022624 11 10 0,000 6,093E-03 0,01359974 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 13 10 0,000 6,093E-03 0,01359124 ! prostaglandin receptor activity GO:0004955 11 10 0,000 6,093E-03 0,01358276 ! regulation of isotype switching GO:0045191 14 10 0,000 6,093E-03 0,01357429 ! peptide transporter activity GO:0015197 10 10 0,000 6,093E-03 0,01356582 ! regulation of leukocyte migration GO:0002685 10 10 0,000 6,093E-03 0,01355737 ! retinoid-X receptor activity GO:0004886 10 10 0,000 6,093E-03 0,01354893 ! GTPase inhibitor activity GO:0005095 10 10 0,000 6,093E-03 0,0135405 ! pattern recognition receptor activity GO:0008329 10 10 0,000 6,093E-03 0,01353208 ! gamma-tubulin complex GO:0000930 12 10 0,000 6,093E-03 0,01352367 ! germ cell migration GO:0008354 10 10 0,000 6,093E-03 0,01351527 ! regulation of organic acid transport GO:0032890 10 10 0,000 6,093E-03 0,01350688 ! cardiac cell differentiation GO:0035051 11 10 0,000 6,093E-03 0,0134985 ! amiloride-sensitive sodium channel activity GO:0015280 10 10 0,000 6,093E-03 0,01349013 ! sterol transporter activity GO:0015248 10 10 0,000 6,093E-03 0,01348177 ! regulation of embryonic development GO:0045995 11 10 0,000 6,093E-03 0,01347343 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 11 11 0,000 6,701E-03 0,01480758 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 11 0,000 6,701E-03 0,01479842 ! negative regulation of blood pressure GO:0045776 11 11 0,000 6,701E-03 0,01478927 ! RNA cap binding GO:0000339 12 11 0,000 6,701E-03 0,01478014 ! CTP metabolic process GO:0046036 12 11 0,000 6,701E-03 0,01477101 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 11 0,000 6,701E-03 0,0147619 ! response to pain GO:0048265 11 11 0,000 6,701E-03 0,0147528 ! axonemal dynein complex GO:0005858 11 11 0,000 6,701E-03 0,01474371 ! eukaryotic translation initiation factor 3 complex GO:0005852 11 11 0,000 6,701E-03 0,01473463 ! dopamine receptor signaling pathway GO:0007212 13 11 0,000 6,701E-03 0,01472557 ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 11 0,000 6,701E-03 0,01471651 ! endocrine pancreas development GO:0031018 11 11 0,000 6,701E-03 0,01470746 ! regulation of interferon-gamma biosynthetic process GO:0045072 12 11 0,000 6,701E-03 0,01469843 ! regulation of exit from mitosis GO:0007096 11 11 0,000 6,701E-03 0,01468941 ! chylomicron GO:0042627 11 11 0,000 6,701E-03 0,0146804 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 11 11 0,000 6,701E-03 0,01467139 ! glycolipid biosynthetic process GO:0009247 11 11 0,000 6,701E-03 0,0146624 ! transforming growth factor beta binding GO:0050431 11 11 0,000 6,701E-03 0,01465343 ! glutamate metabolic process GO:0006536 12 11 0,000 6,701E-03 0,01464446 ! ribonucleotide catabolic process GO:0009261 11 11 0,000 6,701E-03 0,0146355 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 6,701E-03 0,01462656 ! vascular endothelial growth factor receptor activity GO:0005021 11 11 0,000 6,701E-03 0,01461762 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 11 11 0,000 6,701E-03 0,0146087 GO:0045125|bioactive lipid receptor activity, ! epithelial cell development GO:0002064 11 11 0,000 6,701E-03 0,01459978 ! filamentous actin GO:0031941 11 11 0,000 6,701E-03 0,01459088 ! temperature homeostasis GO:0001659 11 11 0,000 6,701E-03 0,01458199 ! structural constituent of epidermis GO:0030280 13 11 0,000 6,701E-03 0,01457311 ! protein targeting to peroxisome GO:0006625 11 11 0,000 6,701E-03 0,01456424 ! spectrin GO:0008091 11 11 0,000 6,701E-03 0,01455538 ! cytoskeletal adaptor activity GO:0008093 14 11 0,000 6,701E-03 0,01454653 ! negative regulation of axonogenesis GO:0050771 13 11 0,000 6,701E-03 0,01453769 ! regulation of phagocytosis GO:0050764 11 11 0,000 6,701E-03 0,01452887 ! nucleoside triphosphate catabolic process GO:0009143 11 11 0,000 6,701E-03 0,01452005 ! synaptic vesicle exocytosis GO:0016079 12 11 0,000 6,701E-03 0,01451125 ! regulation of B cell differentiation GO:0045577 15 11 0,000 6,701E-03 0,01450245 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 11 11 0,000 6,701E-03 0,01449367 ! basal lamina GO:0005605 12 11 0,000 6,701E-03 0,01448489 ! gastrulation with mouth forming second GO:0001702 12 11 0,000 6,701E-03 0,01447613 ! spinal cord motor neuron differentiation GO:0021522 11 11 0,000 6,701E-03 0,01446738 ! hindbrain morphogenesis GO:0021575 13 11 0,000 6,701E-03 0,01445864 ! regulation of hormone metabolic process GO:0032350 12 11 0,000 6,701E-03 0,01444991 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 11 0,000 6,701E-03 0,01444119 GO:0050706|regulation of interleukin-1 beta secretion, ! COPI vesicle coat GO:0030126 11 11 0,000 6,701E-03 0,01443248 GO:0030663|COPI coated vesicle membrane, ! clathrin coat of trans-Golgi network vesicle GO:0030130 14 11 0,000 6,701E-03 0,01442378 ! tRNA-specific ribonuclease activity GO:0004549 11 11 0,000 6,701E-03 0,01441509 ! cofactor transporter activity GO:0051184 11 11 0,000 6,701E-03 0,01440641 ! cobalt ion binding GO:0050897 11 11 0,000 6,701E-03 0,01439774 ! pseudouridine synthase activity GO:0009982 12 11 0,000 6,701E-03 0,01438908 ! aromatic amino acid family catabolic process GO:0009074 12 11 0,000 6,701E-03 0,01438044 ! serine family amino acid biosynthetic process GO:0009070 11 11 0,000 6,701E-03 0,0143718 ! histone deacetylase binding GO:0042826 11 11 0,000 6,701E-03 0,01436317 ! thymus development GO:0048538 12 11 0,000 6,701E-03 0,01435456 ! spleen development GO:0048536 12 11 0,000 6,701E-03 0,01434595 ! regulation of RNA stability GO:0043487 11 11 0,000 6,701E-03 0,01433735 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 12 11 0,000 6,701E-03 0,01432877 ! acid-thiol ligase activity GO:0016878 11 11 0,000 6,701E-03 0,01432019 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 11 11 0,000 6,701E-03 0,01431163 ! cerebellar cortex development GO:0021695 12 11 0,000 6,701E-03 0,01430307 ! regulation of actin filament bundle formation GO:0032231 14 11 0,000 6,701E-03 0,01429453 ! ADP binding GO:0043531 11 11 0,000 6,701E-03 0,014286 ! folic acid binding GO:0005542 11 11 0,000 6,701E-03 0,01427747 ! FK506 binding GO:0005528 11 11 0,000 6,701E-03 0,01426896 GO:0005527|macrolide binding, ! defense response to fungus GO:0050832 11 11 0,000 6,701E-03 0,01426046 ! extracellular matrix binding GO:0050840 13 11 0,000 6,701E-03 0,01425196 ! microspike assembly GO:0030035 13 11 0,000 6,701E-03 0,01424348 ! cytoplasmic sequestering of protein GO:0051220 11 11 0,000 6,701E-03 0,01423501 ! regulation of synapse structure and activity GO:0050803 11 11 0,000 6,701E-03 0,01422654 ! organ formation GO:0048645 12 11 0,000 6,701E-03 0,01421809 ! positive regulation of B cell proliferation GO:0030890 15 11 0,000 6,701E-03 0,01420965 ! embryonic hindlimb morphogenesis GO:0035116 11 11 0,000 6,701E-03 0,01420121 ! embryonic forelimb morphogenesis GO:0035115 11 11 0,000 6,701E-03 0,01419279 ! cellular copper ion homeostasis GO:0006878 12 11 0,000 6,701E-03 0,01418438 ! glycosaminoglycan catabolic process GO:0006027 11 11 0,000 6,701E-03 0,01417597 ! Golgi vesicle budding GO:0048194 11 11 0,000 6,701E-03 0,01416758 ! regulation of positive chemotaxis GO:0050926 11 11 0,000 6,701E-03 0,0141592 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 11 11 0,000 6,701E-03 0,01415082 ! ion channel inhibitor activity GO:0008200 13 11 0,000 6,701E-03 0,01414246 GO:0016248|channel inhibitor activity, ! positive regulation of transcription factor import into nucleus GO:0042993 12 11 0,000 6,701E-03 0,01413411 ! MAP kinase kinase activity GO:0004708 11 11 0,000 6,701E-03 0,01412576 GO:0004712|protein serine/threonine/tyrosine kinase activity, ! cation:amino acid symporter activity GO:0005416 11 11 0,000 6,701E-03 0,01411743 ! mannosyltransferase activity GO:0000030 11 11 0,000 6,701E-03 0,01410911 ! cAMP-dependent protein kinase activity GO:0004691 11 11 0,000 6,701E-03 0,01410079 ! FMN binding GO:0010181 11 11 0,000 6,701E-03 0,01409249 ! response to X-ray GO:0010165 12 11 0,000 6,701E-03 0,01408419 ! focal adhesion formation GO:0048041 13 11 0,000 6,701E-03 0,01407591 ! actin polymerization or depolymerization GO:0008154 13 11 0,000 6,701E-03 0,01406763 ! substrate-bound cell migration GO:0006929 11 11 0,000 6,701E-03 0,01405937 ! integrator complex GO:0032039 11 11 0,000 6,701E-03 0,01405111 ! UV protection GO:0009650 11 11 0,000 6,701E-03 0,01404287 ! L-glutamate transport GO:0015813 11 11 0,000 6,701E-03 0,01403463 GO:0015800|acidic amino acid transport, ! retinol binding GO:0019841 11 11 0,000 6,701E-03 0,0140264 ! regulation of organ growth GO:0046620 12 11 0,000 6,701E-03 0,01401819 ! regulation of cytokine production during immune response GO:0002718 11 11 0,000 6,701E-03 0,01400998 ! regulation of T cell mediated immunity GO:0002709 15 11 0,000 6,701E-03 0,01400178 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 11 11 0,000 6,701E-03 0,01399359 ! regulation of interleukin-8 production GO:0032677 12 11 0,000 6,701E-03 0,01398541 ! histone acetylation GO:0016573 11 11 0,000 6,701E-03 0,01397725 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 12 11 0,000 6,701E-03 0,01396909 ! delayed rectifier potassium channel activity GO:0005251 11 11 0,000 6,701E-03 0,01396094 ! organic cation transmembrane transporter activity GO:0015101 11 11 0,000 6,701E-03 0,0139528 ! chromatin silencing GO:0006342 11 11 0,000 6,701E-03 0,01394466 ! gland morphogenesis GO:0022612 12 11 0,000 6,701E-03 0,01393654 ! sulfate transmembrane transporter activity GO:0015116 11 11 0,000 6,701E-03 0,01392843 ! hexose transmembrane transporter activity GO:0015149 11 11 0,000 6,701E-03 0,01392033 ! icosanoid receptor activity GO:0004953 12 11 0,000 6,701E-03 0,01391224 GO:0004954|prostanoid receptor activity, ! non-G-protein coupled 7TM receptor activity GO:0004926 12 11 0,000 6,701E-03 0,01390415 ! negative regulation of neurological system process GO:0031645 12 11 0,000 6,701E-03 0,01389608 ! acid secretion GO:0046717 11 11 0,000 6,701E-03 0,01388801 ! nitric oxide mediated signal transduction GO:0007263 11 11 0,000 6,701E-03 0,01387996 ! thyroid hormone metabolic process GO:0042403 11 11 0,000 6,701E-03 0,01387191 ! quinone cofactor metabolic process GO:0042375 12 11 0,000 6,701E-03 0,01386387 ! insulin-like growth factor receptor binding GO:0005159 12 11 0,000 6,701E-03 0,01385584 ! midbody GO:0030496 11 11 0,000 6,701E-03 0,01384783 ! interferon-alpha/beta receptor binding GO:0005132 11 11 0,000 6,701E-03 0,01383982 ! cAMP-dependent protein kinase complex GO:0005952 11 11 0,000 6,701E-03 0,01383182 ! water channel activity GO:0015250 11 11 0,000 6,701E-03 0,01382383 ! response to nicotine GO:0035094 11 11 0,000 6,701E-03 0,01381585 ! response to cold GO:0009409 11 11 0,000 6,701E-03 0,01380787 ! adenylate cyclase activity GO:0004016 11 11 0,000 6,701E-03 0,01379991 ! 'de novo' protein folding GO:0006458 12 12 0,000 7,308E-03 0,01504169 ! centriole GO:0005814 12 12 0,000 7,308E-03 0,01503302 ! organellar large ribosomal subunit GO:0000315 13 12 0,000 7,308E-03 0,01502437 GO:0005762|mitochondrial large ribosomal subunit, ! cadmium ion binding GO:0046870 13 12 0,000 7,308E-03 0,01501572 ! folic acid and derivative biosynthetic process GO:0009396 12 12 0,000 7,308E-03 0,01500709 ! bone remodeling GO:0046849 12 12 0,000 7,308E-03 0,01499846 ! peroxisomal transport GO:0043574 12 12 0,000 7,308E-03 0,01498985 ! retina development in camera-type eye GO:0060041 13 12 0,000 7,308E-03 0,01498124 ! hair follicle morphogenesis GO:0031069 12 12 0,000 7,308E-03 0,01497265 ! voltage-gated sodium channel complex GO:0001518 13 12 0,000 7,308E-03 0,01496406 GO:0034706|sodium channel complex, ! regulation of excitatory postsynaptic membrane potential GO:0060079 14 12 0,000 7,308E-03 0,01495549 ! hippocampus development GO:0021766 12 12 0,000 7,308E-03 0,01494692 ! negative regulation of lipid metabolic process GO:0045833 13 12 0,000 7,308E-03 0,01493837 ! T cell selection GO:0045058 16 12 0,000 7,308E-03 0,01492982 ! cation:cation antiporter activity GO:0015491 12 12 0,000 7,308E-03 0,01492129 ! T-tubule GO:0030315 13 12 0,000 7,308E-03 0,01491276 ! methionine metabolic process GO:0006555 13 12 0,000 7,308E-03 0,01490424 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 14 12 0,000 7,308E-03 0,01489574 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! peptide antigen binding GO:0042605 12 12 0,000 7,308E-03 0,01488724 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 7,308E-03 0,01487875 ! cell-cell junction assembly GO:0007043 12 12 0,000 7,308E-03 0,01487027 ! mitotic spindle organization GO:0007052 12 12 0,000 7,308E-03 0,0148618 ! fear response GO:0042596 12 12 0,000 7,308E-03 0,01485335 ! negative regulation of mitotic cell cycle GO:0045930 13 12 0,000 7,308E-03 0,0148449 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 7,308E-03 0,01483646 ! copper ion homeostasis GO:0055070 13 12 0,000 7,308E-03 0,01482803 ! lipoprotein receptor activity GO:0030228 12 12 0,000 7,308E-03 0,01481961 ! axon cargo transport GO:0008088 12 12 0,000 7,308E-03 0,0148112 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 13 12 0,000 7,308E-03 0,0148028 ! transcription elongation factor complex GO:0008023 13 12 0,000 7,308E-03 0,0147944 ! positive regulation of Ras GTPase activity GO:0032320 12 12 0,000 7,308E-03 0,01478602 ! nuclear outer membrane GO:0005640 12 12 0,000 7,308E-03 0,01477765 ! beta-tubulin binding GO:0048487 12 12 0,000 7,308E-03 0,01476929 ! autonomic nervous system development GO:0048483 12 12 0,000 7,308E-03 0,01476093 ! positive regulation of interleukin-1 secretion GO:0050716 12 12 0,000 7,308E-03 0,01475259 GO:0050704|regulation of interleukin-1 secretion, ! exoribonuclease activity GO:0004532 12 12 0,000 7,308E-03 0,01474425 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! cofactor transport GO:0051181 12 12 0,000 7,308E-03 0,01473593 ! regulation of epidermis development GO:0045682 12 12 0,000 7,308E-03 0,01472761 ! protein-chromophore linkage GO:0018298 12 12 0,000 7,308E-03 0,01471931 ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 12 12 0,000 7,308E-03 0,01471101 ! cell killing GO:0001906 12 12 0,000 7,308E-03 0,01470272 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 12 0,000 7,308E-03 0,01469444 ! regulation of fatty acid oxidation GO:0046320 13 12 0,000 7,308E-03 0,01468617 ! detection of bacterium GO:0016045 13 12 0,000 7,308E-03 0,01467791 ! positive regulation of neuron apoptosis GO:0043525 12 12 0,000 7,308E-03 0,01466966 ! dystrophin-associated glycoprotein complex GO:0016010 14 12 0,000 7,308E-03 0,01466142 ! internal side of plasma membrane GO:0009898 14 12 0,000 7,308E-03 0,01465319 ! RNA 3'-end processing GO:0031123 12 12 0,000 7,308E-03 0,01464497 ! developmental induction GO:0031128 13 12 0,000 7,308E-03 0,01463675 GO:0045168|cell-cell signaling involved in cell fate specification, ! fibrillar collagen GO:0005583 13 12 0,000 7,308E-03 0,01462855 ! positive regulation of calcium-mediated signaling GO:0050850 14 12 0,000 7,308E-03 0,01462035 ! inner ear receptor cell differentiation GO:0060113 13 12 0,000 7,308E-03 0,01461217 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 7,308E-03 0,01460399 ! very-long-chain fatty acid metabolic process GO:0000038 12 12 0,000 7,308E-03 0,01459582 ! negative regulation of cell projection organization GO:0031345 14 12 0,000 7,308E-03 0,01458766 ! thyroid gland development GO:0030878 12 12 0,000 7,308E-03 0,01457951 ! non-recombinational repair GO:0000726 12 12 0,000 7,308E-03 0,01457137 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 12 12 0,000 7,308E-03 0,01456324 ! lipid localization GO:0010876 12 12 0,000 7,308E-03 0,01455512 GO:0019915|lipid storage, ! regulation of glycolysis GO:0006110 12 12 0,000 7,308E-03 0,01454701 ! response to cAMP GO:0051591 12 12 0,000 7,308E-03 0,0145389 ! negative regulation of transcription factor import into nucleus GO:0042992 12 12 0,000 7,308E-03 0,01453081 ! T cell proliferation GO:0042098 17 12 0,000 7,308E-03 0,01452272 ! negative regulation of protein amino acid phosphorylation GO:0001933 16 12 0,000 7,308E-03 0,01451464 ! receptor signaling protein tyrosine kinase activity GO:0004716 13 12 0,000 7,308E-03 0,01450657 ! two-component signal transduction system (phosphorelay) GO:0000160 13 12 0,000 7,308E-03 0,01449852 ! peptide or protein amino-terminal blocking GO:0018409 13 12 0,000 7,308E-03 0,01449047 ! drug transport GO:0015893 12 12 0,000 7,308E-03 0,01448242 ! GTP-dependent protein binding GO:0030742 12 12 0,000 7,308E-03 0,01447439 ! regulation of interleukin-6 biosynthetic process GO:0045408 12 12 0,000 7,308E-03 0,01446637 ! T cell receptor complex GO:0042101 12 12 0,000 7,308E-03 0,01445835 ! membrane protein proteolysis GO:0033619 13 12 0,000 7,308E-03 0,01445035 GO:0006509|membrane protein ectodomain proteolysis, ! protein disulfide oxidoreductase activity GO:0015035 12 12 0,000 7,308E-03 0,01444235 ! histone acetyltransferase complex GO:0000123 13 12 0,000 7,308E-03 0,01443436 ! dendritic spine GO:0043197 12 12 0,000 7,308E-03 0,01442638 ! ATP-binding cassette (ABC) transporter complex GO:0043190 12 12 0,000 7,308E-03 0,01441841 ! alpha-beta T cell activation GO:0046631 13 12 0,000 7,308E-03 0,01441045 ! organic anion transmembrane transporter activity GO:0008514 13 12 0,000 7,308E-03 0,0144025 ! vasoconstriction GO:0042310 13 12 0,000 7,308E-03 0,01439455 ! DNA unwinding during replication GO:0006268 12 12 0,000 7,308E-03 0,01438662 ! cellular amino acid derivative catabolic process GO:0042219 16 12 0,000 7,308E-03 0,01437869 ! mRNA splice site selection GO:0006376 13 12 0,000 7,308E-03 0,01437078 ! phosphate transmembrane transporter activity GO:0015114 13 12 0,000 7,308E-03 0,01436287 ! trans-Golgi network transport vesicle membrane GO:0012510 15 12 0,000 7,308E-03 0,01435497 ! ubiquitin protein ligase binding GO:0031625 12 12 0,000 7,308E-03 0,01434707 ! monosaccharide transmembrane transporter activity GO:0015145 12 12 0,000 7,308E-03 0,01433919 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 12 12 0,000 7,308E-03 0,01433132 ! hexosaminidase activity GO:0015929 12 12 0,000 7,308E-03 0,01432345 ! diacylglycerol kinase activity GO:0004143 13 12 0,000 7,308E-03 0,01431559 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 7,308E-03 0,01430775 ! activation of NF-kappaB-inducing kinase activity GO:0007250 12 12 0,000 7,308E-03 0,01429991 ! protein kinase C binding GO:0005080 13 12 0,000 7,308E-03 0,01429207 ! catecholamine biosynthetic process GO:0042423 13 12 0,000 7,308E-03 0,01428425 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 15 12 0,000 7,308E-03 0,01427644 ! establishment or maintenance of apical/basal cell polarity GO:0035088 12 12 0,000 7,308E-03 0,01426863 ! L-fucose metabolic process GO:0042354 14 12 0,000 7,308E-03 0,01426083 ! acylglycerol O-acyltransferase activity GO:0016411 12 12 0,000 7,308E-03 0,01425305 ! C-acyltransferase activity GO:0016408 12 12 0,000 7,308E-03 0,01424527 ! steroid hydroxylase activity GO:0008395 12 12 0,000 7,308E-03 0,01423749 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 7,308E-03 0,01422973 ! calcium-activated potassium channel activity GO:0015269 14 12 0,000 7,308E-03 0,01422198 ! SWI/SNF-type complex GO:0070603 13 12 0,000 7,308E-03 0,01421423 GO:0016514|SWI/SNF complex, ! cilium part GO:0044441 12 12 0,000 7,308E-03 0,01420649 ! positive regulation of translation GO:0045727 13 13 0,000 7,915E-03 0,01537782 ! ER-associated protein catabolic process GO:0030433 13 13 0,000 7,915E-03 0,01536946 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 7,915E-03 0,0153611 ! pteridine and derivative biosynthetic process GO:0042559 14 13 0,000 7,915E-03 0,01535276 ! cis-Golgi network GO:0005801 14 13 0,000 7,915E-03 0,01534443 ! regulation of S phase GO:0033261 17 13 0,000 7,915E-03 0,0153361 ! regulation of chemokine production GO:0032642 13 13 0,000 7,915E-03 0,01532778 ! phospholipid catabolic process GO:0009395 14 13 0,000 7,915E-03 0,01531948 ! positive regulation of GTPase activity GO:0043547 14 13 0,000 7,915E-03 0,01531118 ! endothelial cell migration GO:0043542 13 13 0,000 7,915E-03 0,01530289 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 13 13 0,000 7,915E-03 0,01529461 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 7,915E-03 0,01528633 ! cartilage condensation GO:0001502 14 13 0,000 7,915E-03 0,01527807 ! organelle fusion GO:0048284 14 13 0,000 7,915E-03 0,01526982 ! positive regulation of lipid metabolic process GO:0045834 13 13 0,000 7,915E-03 0,01526157 ! pseudouridine synthesis GO:0001522 14 13 0,000 7,915E-03 0,01525334 ! negative regulation of gene expression, epigenetic GO:0045814 13 13 0,000 7,915E-03 0,01524511 ! regulation of interleukin-2 biosynthetic process GO:0045076 13 13 0,000 7,915E-03 0,01523689 ! negative regulation of proteolysis GO:0045861 13 13 0,000 7,915E-03 0,01522868 ! regulation of mRNA processing GO:0050684 13 13 0,000 7,915E-03 0,01522048 ! arginine metabolic process GO:0006525 13 13 0,000 7,915E-03 0,01521229 ! WW domain binding GO:0050699 14 13 0,000 7,915E-03 0,01520411 ! cholesterol binding GO:0015485 13 13 0,000 7,915E-03 0,01519593 ! negative regulation of microtubule depolymerization GO:0007026 15 13 0,000 7,915E-03 0,01518777 GO:0031114|regulation of microtubule depolymerization, ! Golgi organization GO:0007030 16 13 0,000 7,915E-03 0,01517961 ! negative regulation of endothelial cell migration GO:0010596 13 13 0,000 7,915E-03 0,01517146 ! integral to peroxisomal membrane GO:0005779 13 13 0,000 7,915E-03 0,01516332 GO:0031231|intrinsic to peroxisomal membrane, ! integral to membrane of membrane fraction GO:0000299 14 13 0,000 7,915E-03 0,01515519 ! regulation of heart rate GO:0002027 14 13 0,000 7,915E-03 0,01514707 ! positive regulation of carbohydrate metabolic process GO:0045913 14 13 0,000 7,915E-03 0,01513896 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 14 13 0,000 7,915E-03 0,01513085 ! negative regulation of immune response GO:0050777 17 13 0,000 7,915E-03 0,01512276 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 13 0,000 7,915E-03 0,01511467 ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 7,915E-03 0,01510659 ! response to estradiol stimulus GO:0032355 14 13 0,000 7,915E-03 0,01509852 ! anaphase-promoting complex GO:0005680 13 13 0,000 7,915E-03 0,01509046 ! nucleotide diphosphatase activity GO:0004551 13 13 0,000 7,915E-03 0,01508241 ! regulation of erythrocyte differentiation GO:0045646 13 13 0,000 7,915E-03 0,01507436 ! intestinal absorption GO:0050892 13 13 0,000 7,915E-03 0,01506633 ! eukaryotic cell surface binding GO:0043499 14 13 0,000 7,915E-03 0,0150583 ! digestive tract morphogenesis GO:0048546 13 13 0,000 7,915E-03 0,01505028 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 14 13 0,000 7,915E-03 0,01504227 ! regulation of cellular carbohydrate catabolic process GO:0043471 14 13 0,000 7,915E-03 0,01503427 GO:0043470|regulation of carbohydrate catabolic process, ! tropomyosin binding GO:0005523 13 13 0,000 7,915E-03 0,01502628 ! carbon-sulfur lyase activity GO:0016846 13 13 0,000 7,915E-03 0,0150183 ! positive regulation of protein polymerization GO:0032273 13 13 0,000 7,915E-03 0,01501032 ! insulin secretion GO:0030073 13 13 0,000 7,915E-03 0,01500235 ! regulation of protein ubiquitination GO:0031396 13 13 0,000 7,915E-03 0,01499439 ! positive regulation of cellular catabolic process GO:0031331 14 13 0,000 7,915E-03 0,01498644 ! G1 phase of mitotic cell cycle GO:0000080 13 13 0,000 7,915E-03 0,0149785 ! replisome GO:0030894 14 13 0,000 7,915E-03 0,01497057 GO:0043601|nuclear replisome, ! regulation of nitric-oxide synthase activity GO:0050999 13 13 0,000 7,915E-03 0,01496264 ! double-strand break repair via homologous recombination GO:0000724 13 13 0,000 7,915E-03 0,01495473 GO:0000725|recombinational repair, ! copper ion transport GO:0006825 13 13 0,000 7,915E-03 0,01494682 ! regulation of cell-cell adhesion GO:0022407 13 13 0,000 7,915E-03 0,01493892 ! forelimb morphogenesis GO:0035136 13 13 0,000 7,915E-03 0,01493103 ! mating GO:0007618 13 13 0,000 7,915E-03 0,01492314 ! phosphatidylinositol phosphate kinase activity GO:0016307 14 13 0,000 7,915E-03 0,01491527 ! MAP kinase activity GO:0004707 14 13 0,000 7,915E-03 0,0149074 ! cytokine biosynthetic process GO:0042089 13 13 0,000 7,915E-03 0,01489954 ! ventral spinal cord development GO:0021517 13 13 0,000 7,915E-03 0,01489169 ! prenyltransferase activity GO:0004659 14 13 0,000 7,915E-03 0,01488385 ! platelet-derived growth factor receptor signaling pathway GO:0048008 15 13 0,000 7,915E-03 0,01487602 ! regulation of skeletal muscle fiber development GO:0048742 13 13 0,000 7,915E-03 0,01486819 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 15 13 0,000 7,915E-03 0,01486037 ! protein kinase C activity GO:0004697 15 13 0,000 7,915E-03 0,01485257 ! oligodendrocyte differentiation GO:0048709 13 13 0,000 7,915E-03 0,01484477 ! water transporter activity GO:0005372 13 13 0,000 7,915E-03 0,01483697 ! exocrine system development GO:0035272 14 13 0,000 7,915E-03 0,01482919 ! dicarboxylic acid transmembrane transporter activity GO:0005310 13 13 0,000 7,915E-03 0,01482141 ! monoamine transport GO:0015844 13 13 0,000 7,915E-03 0,01481364 ! CoA hydrolase activity GO:0016289 13 13 0,000 7,915E-03 0,01480588 ! embryo implantation GO:0007566 13 13 0,000 7,915E-03 0,01479813 ! G1/S transition checkpoint GO:0031575 13 13 0,000 7,915E-03 0,01479039 ! positive regulation of alpha-beta T cell differentiation GO:0046638 13 13 0,000 7,915E-03 0,01478265 ! immunoglobulin binding GO:0019865 13 13 0,000 7,915E-03 0,01477493 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 7,915E-03 0,01476721 ! anchored to plasma membrane GO:0046658 14 13 0,000 7,915E-03 0,0147595 ! MHC class I protein binding GO:0042288 13 13 0,000 7,915E-03 0,01475179 ! histone deacetylation GO:0016575 13 13 0,000 7,915E-03 0,0147441 ! calcium channel regulator activity GO:0005246 14 13 0,000 7,915E-03 0,01473641 ! neuroblast proliferation GO:0007405 13 13 0,000 7,915E-03 0,01472873 ! peptide biosynthetic process GO:0043043 14 13 0,000 7,915E-03 0,01472106 ! response to gamma radiation GO:0010332 13 13 0,000 7,915E-03 0,0147134 ! sarcomere organization GO:0045214 13 13 0,000 7,915E-03 0,01470574 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 15 13 0,000 7,915E-03 0,01469809 ! cAMP binding GO:0030552 13 13 0,000 7,915E-03 0,01469045 ! fucosyltransferase activity GO:0008417 14 13 0,000 7,915E-03 0,01468282 ! cilium assembly GO:0042384 13 13 0,000 7,915E-03 0,0146752 ! bacterial binding GO:0008367 13 13 0,000 7,915E-03 0,01466758 ! regulation of NF-kappaB import into nucleus GO:0042345 13 13 0,000 7,915E-03 0,01465998 ! acrosome reaction GO:0007340 13 13 0,000 7,915E-03 0,01465238 ! microtubule-based flagellum GO:0009434 13 13 0,000 7,915E-03 0,01464478 ! nucleolar part GO:0044452 13 13 0,000 7,915E-03 0,0146372 ! axoneme part GO:0044447 13 13 0,000 7,915E-03 0,01462962 ! tRNA modification GO:0006400 14 14 0,000 8,522E-03 0,01574256 ! positive regulation of blood pressure GO:0045777 15 14 0,000 8,522E-03 0,01573442 ! transferase activity, transferring amino-acyl groups GO:0016755 14 14 0,000 8,522E-03 0,01572628 ! negative regulation of bone remodeling GO:0046851 14 14 0,000 8,522E-03 0,01571816 ! 2'-deoxyribonucleotide metabolic process GO:0009394 15 14 0,000 8,522E-03 0,01571005 GO:0019692|deoxyribose phosphate metabolic process, ! transcription from RNA polymerase III promoter GO:0006383 14 14 0,000 8,522E-03 0,01570194 ! guanylate kinase activity GO:0004385 16 14 0,000 8,522E-03 0,01569384 ! striated muscle thin filament GO:0005865 15 14 0,000 8,522E-03 0,01568575 ! patterning of blood vessels GO:0001569 14 14 0,000 8,522E-03 0,01567767 ! mechanoreceptor differentiation GO:0042490 15 14 0,000 8,522E-03 0,0156696 ! palate development GO:0060021 15 14 0,000 8,522E-03 0,01566153 ! centrosome cycle GO:0007098 14 14 0,000 8,522E-03 0,01565348 ! regulation of defense response to virus GO:0050688 14 14 0,000 8,522E-03 0,01564543 ! cAMP-dependent protein kinase regulator activity GO:0008603 14 14 0,000 8,522E-03 0,01563739 ! ephrin receptor activity GO:0005003 16 14 0,000 8,522E-03 0,01562936 ! protein polyubiquitination GO:0000209 15 14 0,000 8,522E-03 0,01562134 ! glycine metabolic process GO:0006544 15 14 0,000 8,522E-03 0,01561332 ! plasma membrane organization GO:0007009 14 14 0,000 8,522E-03 0,01560531 ! tyrosine metabolic process GO:0006570 16 14 0,000 8,522E-03 0,01559731 ! response to retinoic acid GO:0032526 14 14 0,000 8,522E-03 0,01558932 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 16 14 0,000 8,522E-03 0,01558134 ! lysosomal transport GO:0007041 14 14 0,000 8,522E-03 0,01557337 ! rough endoplasmic reticulum GO:0005791 14 14 0,000 8,522E-03 0,0155654 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 14 14 0,000 8,522E-03 0,01555744 ! regulation of the force of heart contraction GO:0002026 15 14 0,000 8,522E-03 0,01554949 ! bone mineralization GO:0030282 14 14 0,000 8,522E-03 0,01554155 ! protein kinase activator activity GO:0030295 14 14 0,000 8,522E-03 0,01553362 ! NLS-bearing substrate import into nucleus GO:0006607 15 14 0,000 8,522E-03 0,01552569 ! cerebellum development GO:0021549 15 14 0,000 8,522E-03 0,01551778 ! G1 phase GO:0051318 14 14 0,000 8,522E-03 0,01550987 ! negative regulation of blood coagulation GO:0030195 16 14 0,000 8,522E-03 0,01550197 ! negative regulation of protein secretion GO:0050709 14 14 0,000 8,522E-03 0,01549407 ! water homeostasis GO:0030104 14 14 0,000 8,522E-03 0,01548619 ! peptide hormone binding GO:0017046 14 14 0,000 8,522E-03 0,01547831 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 8,522E-03 0,01547044 ! glutamine family amino acid biosynthetic process GO:0009084 15 14 0,000 8,522E-03 0,01546258 ! regulation of ATPase activity GO:0043462 15 14 0,000 8,522E-03 0,01545473 ! regulation of leukocyte mediated cytotoxicity GO:0001910 18 14 0,000 8,522E-03 0,01544688 ! positive regulation of calcium ion transport GO:0051928 17 14 0,000 8,522E-03 0,01543905 ! regulation of blood vessel endothelial cell migration GO:0043535 14 14 0,000 8,522E-03 0,01543122 ! regulation of calcium-mediated signaling GO:0050848 16 14 0,000 8,522E-03 0,0154234 ! positive regulation of synaptic transmission GO:0050806 14 14 0,000 8,522E-03 0,01541558 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 16 14 0,000 8,522E-03 0,01540778 ! lactation GO:0007595 15 14 0,000 8,522E-03 0,01539998 ! reproductive cellular process GO:0048610 14 14 0,000 8,522E-03 0,01539219 ! positive regulation of cell killing GO:0031343 18 14 0,000 8,522E-03 0,01538441 ! sulfur amino acid biosynthetic process GO:0000097 15 14 0,000 8,522E-03 0,01537664 ! dicarboxylic acid transport GO:0006835 14 14 0,000 8,522E-03 0,01536887 ! inorganic anion exchanger activity GO:0005452 15 14 0,000 8,522E-03 0,01536111 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 15 14 0,000 8,522E-03 0,01535336 ! negative regulation of cytokine biosynthetic process GO:0042036 14 14 0,000 8,522E-03 0,01534562 ! negative regulation of ion transport GO:0043271 14 14 0,000 8,522E-03 0,01533788 ! retinoic acid receptor binding GO:0042974 14 14 0,000 8,522E-03 0,01533016 ! startle response GO:0001964 14 14 0,000 8,522E-03 0,01532244 ! 2 iron, 2 sulfur cluster binding GO:0051537 14 14 0,000 8,522E-03 0,01531473 ! activation of MAPKK activity GO:0000186 15 14 0,000 8,522E-03 0,01530702 ! response to hexose stimulus GO:0009746 14 14 0,000 8,522E-03 0,01529933 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! cytokine metabolic process GO:0042107 14 14 0,000 8,522E-03 0,01529164 ! organic alcohol transport GO:0015850 15 14 0,000 8,522E-03 0,01528396 ! preassembly of GPI anchor in ER membrane GO:0016254 15 14 0,000 8,522E-03 0,01527629 ! calcium ion transmembrane transporter activity GO:0015085 16 14 0,000 8,522E-03 0,01526862 ! eukaryotic translation initiation factor 4F complex GO:0016281 14 14 0,000 8,522E-03 0,01526096 ! nucleoside kinase activity GO:0019206 17 14 0,000 8,522E-03 0,01525331 ! L-amino acid transport GO:0015807 14 14 0,000 8,522E-03 0,01524567 ! microfilament motor activity GO:0000146 14 14 0,000 8,522E-03 0,01523804 ! stem cell development GO:0048864 14 14 0,000 8,522E-03 0,01523041 GO:0019827|stem cell maintenance, ! positive regulation of protein import into nucleus GO:0042307 15 14 0,000 8,522E-03 0,01522279 ! DNA replication initiation GO:0006270 14 14 0,000 8,522E-03 0,01521518 ! T cell differentiation in the thymus GO:0033077 18 14 0,000 8,522E-03 0,01520758 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 8,522E-03 0,01519998 ! calcium activated cation channel activity GO:0005227 16 14 0,000 8,522E-03 0,01519239 ! sulfuric ester hydrolase activity GO:0008484 15 14 0,000 8,522E-03 0,01518481 ! serotonin receptor activity GO:0004993 14 14 0,000 8,522E-03 0,01517724 ! positive regulation of bone mineralization GO:0030501 15 14 0,000 8,522E-03 0,01516967 ! synaptic transmission, cholinergic GO:0007271 15 14 0,000 8,522E-03 0,01516211 ! dopamine metabolic process GO:0042417 17 14 0,000 8,522E-03 0,01515456 ! cAMP biosynthetic process GO:0006171 14 14 0,000 8,522E-03 0,01514702 ! ion gated channel activity GO:0022839 16 14 0,000 8,522E-03 0,01513948 ! male genitalia development GO:0030539 14 14 0,000 8,522E-03 0,01513195 ! regulation of axon extension GO:0030516 15 14 0,000 8,522E-03 0,01512443 ! regulation of BMP signaling pathway GO:0030510 14 14 0,000 8,522E-03 0,01511692 ! estrogen receptor signaling pathway GO:0030520 14 14 0,000 8,522E-03 0,01510941 ! interleukin-1 receptor binding GO:0005149 14 14 0,000 8,522E-03 0,01510192 ! defense response to virus GO:0051607 19 14 0,000 8,522E-03 0,01509442 ! cadherin binding GO:0045296 16 14 0,000 8,522E-03 0,01508694 ! negative regulation of hormone secretion GO:0046888 16 15 0,000 9,128E-03 0,01615219 ! nuclear replication fork GO:0043596 16 15 0,000 9,128E-03 0,01614419 ! phosphoinositide phosphorylation GO:0046854 16 15 0,000 9,128E-03 0,01613619 GO:0046834|lipid phosphorylation, ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 9,128E-03 0,01612821 ! cardiac muscle contraction GO:0060048 16 15 0,000 9,128E-03 0,01612023 ! mitotic chromosome condensation GO:0007076 15 15 0,000 9,128E-03 0,01611226 ! regulation of viral genome replication GO:0045069 15 15 0,000 9,128E-03 0,0161043 ! regulation of survival gene product expression GO:0045884 15 15 0,000 9,128E-03 0,01609635 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 15 0,000 9,128E-03 0,01608841 ! glycoprotein catabolic process GO:0006516 15 15 0,000 9,128E-03 0,01608047 ! DNA duplex unwinding GO:0032508 15 15 0,000 9,128E-03 0,01607254 GO:0032392|DNA geometric change, ! glutamine metabolic process GO:0006541 16 15 0,000 9,128E-03 0,01606462 ! proton-transporting V-type ATPase complex GO:0033176 15 15 0,000 9,128E-03 0,0160567 ! response to vitamin A GO:0033189 15 15 0,000 9,128E-03 0,0160488 ! protease binding GO:0002020 16 15 0,000 9,128E-03 0,0160409 ! regulation of ion transmembrane transporter activity GO:0032412 15 15 0,000 9,128E-03 0,01603301 ! actin filament bundle formation GO:0051017 15 15 0,000 9,128E-03 0,01602513 ! calcium ion-dependent exocytosis GO:0017156 15 15 0,000 9,128E-03 0,01601725 ! purine nucleoside monophosphate metabolic process GO:0009126 16 15 0,000 9,128E-03 0,01600939 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! protein export from nucleus GO:0006611 15 15 0,000 9,128E-03 0,01600153 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 9,128E-03 0,01599368 ! positive regulation of biomineral formation GO:0070169 16 15 0,000 9,128E-03 0,01598583 ! positive regulation of oxidoreductase activity GO:0051353 15 15 0,000 9,128E-03 0,015978 ! filopodium GO:0030175 15 15 0,000 9,128E-03 0,01597017 ! negative regulation of inflammatory response GO:0050728 15 15 0,000 9,128E-03 0,01596235 ! positive regulation of transmission of nerve impulse GO:0051971 15 15 0,000 9,128E-03 0,01595453 ! branched chain family amino acid metabolic process GO:0009081 15 15 0,000 9,128E-03 0,01594673 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 9,128E-03 0,01593893 ! heme biosynthetic process GO:0006783 15 15 0,000 9,128E-03 0,01593114 ! SMAD binding GO:0046332 16 15 0,000 9,128E-03 0,01592336 ! nerve development GO:0021675 16 15 0,000 9,128E-03 0,01591558 ! epithelial to mesenchymal transition GO:0001837 16 15 0,000 9,128E-03 0,01590781 ! mannose binding GO:0005537 15 15 0,000 9,128E-03 0,01590005 ! phosphoprotein binding GO:0051219 17 15 0,000 9,128E-03 0,0158923 ! mismatched DNA binding GO:0030983 15 15 0,000 9,128E-03 0,01588456 ! antigen receptor-mediated signaling pathway GO:0050851 21 15 0,000 9,128E-03 0,01587682 ! regulation of skeletal muscle tissue development GO:0048641 15 15 0,000 9,128E-03 0,01586909 ! synaptonemal complex GO:0000795 15 15 0,000 9,128E-03 0,01586137 ! N-terminal protein amino acid modification GO:0031365 16 15 0,000 9,128E-03 0,01585365 ! positive regulation of protein complex assembly GO:0031334 15 15 0,000 9,128E-03 0,01584595 ! water transport GO:0006833 15 15 0,000 9,128E-03 0,01583825 GO:0042044|fluid transport, ! phosphatidylinositol metabolic process GO:0046488 16 15 0,000 9,128E-03 0,01583055 ! viral genome replication GO:0019079 15 15 0,000 9,128E-03 0,01582287 ! phosphatidylcholine metabolic process GO:0046470 17 15 0,000 9,128E-03 0,01581519 ! inositol metabolic process GO:0006020 15 15 0,000 9,128E-03 0,01580752 ! sulfate transport GO:0008272 15 15 0,000 9,128E-03 0,01579986 ! protein-lipid complex GO:0032994 15 15 0,000 9,128E-03 0,01579221 GO:0034358|plasma lipoprotein particle, ! positive regulation of ion transport GO:0043270 18 15 0,000 9,128E-03 0,01578456 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 15 15 0,000 9,128E-03 0,01577692 ! heart looping GO:0001947 15 15 0,000 9,128E-03 0,01576928 ! isoprenoid biosynthetic process GO:0008299 16 15 0,000 9,128E-03 0,01576166 ! protein histidine kinase activity GO:0004673 16 15 0,000 9,128E-03 0,01575404 GO:0000155|two-component sensor activity, ! cardiac muscle tissue development GO:0048738 15 15 0,000 9,128E-03 0,01574643 ! regulation of striated muscle contraction GO:0006942 16 15 0,000 9,128E-03 0,01573883 ! response to osmotic stress GO:0006970 16 15 0,000 9,128E-03 0,01573123 ! fructose metabolic process GO:0006000 15 15 0,000 9,128E-03 0,01572364 ! ubiquitin binding GO:0043130 15 15 0,000 9,128E-03 0,01571606 ! vesicle coating GO:0006901 16 15 0,000 9,128E-03 0,01570849 ! DNA integration GO:0015074 16 15 0,000 9,128E-03 0,01570092 ! alcohol binding GO:0043178 16 15 0,000 9,128E-03 0,01569336 ! disulfide oxidoreductase activity GO:0015036 15 15 0,000 9,128E-03 0,01568581 ! intermediate filament cytoskeleton organization GO:0045104 16 15 0,000 9,128E-03 0,01567826 ! regulation of vasodilation GO:0042312 15 15 0,000 9,128E-03 0,01567073 ! genitalia development GO:0048806 15 15 0,000 9,128E-03 0,0156632 ! structural constituent of eye lens GO:0005212 15 15 0,000 9,128E-03 0,01565567 ! regulation of monooxygenase activity GO:0032768 15 15 0,000 9,128E-03 0,01564816 ! voltage-gated sodium channel activity GO:0005248 17 15 0,000 9,128E-03 0,01564065 ! ribonucleoprotein binding GO:0043021 16 15 0,000 9,128E-03 0,01563315 ! proton-transporting ATP synthase complex GO:0045259 15 15 0,000 9,128E-03 0,01562565 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 15 15 0,000 9,128E-03 0,01561817 ! regulation of immunoglobulin production GO:0002637 19 15 0,000 9,128E-03 0,01561069 ! retinoic acid receptor activity GO:0003708 15 15 0,000 9,128E-03 0,01560321 ! receptor activator activity GO:0030546 15 15 0,000 9,128E-03 0,01559575 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 15 15 0,000 9,128E-03 0,01558829 ! protein transmembrane transporter activity GO:0008320 15 15 0,000 9,128E-03 0,01558084 ! histone binding GO:0042393 15 15 0,000 9,128E-03 0,01557339 ! phosphoinositide 3-kinase activity GO:0035004 16 15 0,000 9,128E-03 0,01556596 ! sialyltransferase activity GO:0008373 15 15 0,000 9,128E-03 0,01555853 ! platelet-derived growth factor receptor binding GO:0005161 16 15 0,000 9,128E-03 0,0155511 ! drug transporter activity GO:0015238 15 15 0,000 9,128E-03 0,01554369 ! negative regulation of homeostatic process GO:0032845 15 15 0,000 9,128E-03 0,01553628 ! phosphoinositide 3-kinase complex GO:0005942 16 15 0,000 9,128E-03 0,01552888 ! binding of sperm to zona pellucida GO:0007339 16 15 0,000 9,128E-03 0,01552148 ! peptide hormone processing GO:0016486 17 15 0,000 9,128E-03 0,01551409 ! aldo-keto reductase activity GO:0004033 15 15 0,000 9,128E-03 0,01550671 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 9,128E-03 0,01549934 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 16 16 0,000 9,734E-03 0,01652029 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 9,734E-03 0,01651244 ! positive regulation of hormone secretion GO:0046887 17 16 0,000 9,734E-03 0,0165046 ! protein amino acid ADP-ribosylation GO:0006471 18 16 0,000 9,734E-03 0,01649677 ! response to vitamin GO:0033273 16 16 0,000 9,734E-03 0,01648894 ! gene silencing by RNA GO:0031047 16 16 0,000 9,734E-03 0,01648112 ! regulation of postsynaptic membrane potential GO:0060078 18 16 0,000 9,734E-03 0,01647331 ! kinesin complex GO:0005871 16 16 0,000 9,734E-03 0,01646551 ! cornified envelope GO:0001533 18 16 0,000 9,734E-03 0,01645771 ! regulation of transmembrane transporter activity GO:0022898 16 16 0,000 9,734E-03 0,01644992 GO:0032409|regulation of transporter activity, ! negative regulation of epithelial cell proliferation GO:0050680 17 16 0,000 9,734E-03 0,01644214 ! pyrimidine ribonucleotide metabolic process GO:0009218 18 16 0,000 9,734E-03 0,01643437 ! pituitary gland development GO:0021983 16 16 0,000 9,734E-03 0,0164266 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 18 16 0,000 9,734E-03 0,01641884 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 19 16 0,000 9,734E-03 0,01641109 ! cell-substrate junction assembly GO:0007044 18 16 0,000 9,734E-03 0,01640334 ! peptidyl-serine phosphorylation GO:0018105 16 16 0,000 9,734E-03 0,01639561 ! branching involved in ureteric bud morphogenesis GO:0001658 16 16 0,000 9,734E-03 0,01638788 GO:0060675|ureteric bud morphogenesis, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 16 16 0,000 9,734E-03 0,01638015 ! nucleobase metabolic process GO:0009112 19 16 0,000 9,734E-03 0,01637244 ! beta-catenin binding GO:0008013 17 16 0,000 9,734E-03 0,01636473 ! regulation of steroid metabolic process GO:0019218 17 16 0,000 9,734E-03 0,01635703 ! neuron recognition GO:0008038 17 16 0,000 9,734E-03 0,01634933 ! oogenesis GO:0048477 19 16 0,000 9,734E-03 0,01634165 ! low-density lipoprotein binding GO:0030169 17 16 0,000 9,734E-03 0,01633397 ! clathrin vesicle coat GO:0030125 19 16 0,000 9,734E-03 0,0163263 ! COPI-coated vesicle GO:0030137 16 16 0,000 9,734E-03 0,01631863 ! sphingolipid biosynthetic process GO:0030148 16 16 0,000 9,734E-03 0,01631097 ! biomineral formation GO:0031214 16 16 0,000 9,734E-03 0,01630332 ! vitamin transport GO:0051180 16 16 0,000 9,734E-03 0,01629568 ! folic acid and derivative metabolic process GO:0006760 16 16 0,000 9,734E-03 0,01628804 ! organic cation transport GO:0015695 16 16 0,000 9,734E-03 0,01628041 ! proximal/distal pattern formation GO:0009954 16 16 0,000 9,734E-03 0,01627279 ! regulation of glucose import GO:0046324 17 16 0,000 9,734E-03 0,01626518 GO:0010827|regulation of glucose transport, ! aromatic compound biosynthetic process GO:0019438 17 16 0,000 9,734E-03 0,01625757 ! aromatic compound catabolic process GO:0019439 18 16 0,000 9,734E-03 0,01624997 ! negative regulation of coagulation GO:0050819 18 16 0,000 9,734E-03 0,01624238 ! tRNA binding GO:0000049 16 16 0,000 9,734E-03 0,01623479 ! regulation of cell killing GO:0031341 20 16 0,000 9,734E-03 0,01622721 ! negative regulation of defense response GO:0031348 16 16 0,000 9,734E-03 0,01621964 ! regulation of neuronal synaptic plasticity GO:0048168 16 16 0,000 9,734E-03 0,01621207 ! hindlimb morphogenesis GO:0035137 16 16 0,000 9,734E-03 0,01620452 ! bile acid metabolic process GO:0008206 16 16 0,000 9,734E-03 0,01619696 ! axis specification GO:0009798 16 16 0,000 9,734E-03 0,01618942 ! adult walking behavior GO:0007628 17 16 0,000 9,734E-03 0,01618188 ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 18 16 0,000 9,734E-03 0,01617435 ! protein phosphatase binding GO:0019903 17 16 0,000 9,734E-03 0,01616683 ! epidermis morphogenesis GO:0048730 16 16 0,000 9,734E-03 0,01615931 ! acyl-CoA dehydrogenase activity GO:0003995 16 16 0,000 9,734E-03 0,01615181 ! complement activation, alternative pathway GO:0006957 16 16 0,000 9,734E-03 0,0161443 ! SH2 domain binding GO:0042169 19 16 0,000 9,734E-03 0,01613681 ! UDP-galactosyltransferase activity GO:0035250 17 16 0,000 9,734E-03 0,01612932 ! RNA methyltransferase activity GO:0008173 16 16 0,000 9,734E-03 0,01612184 ! neutral amino acid transport GO:0015804 16 16 0,000 9,734E-03 0,01611436 ! glucuronosyltransferase activity GO:0015020 17 16 0,000 9,734E-03 0,0161069 ! regulation of alpha-beta T cell differentiation GO:0046637 16 16 0,000 9,734E-03 0,01609944 ! cellular pigmentation GO:0033059 16 16 0,000 9,734E-03 0,01609198 ! mannosidase activity GO:0015923 19 16 0,000 9,734E-03 0,01608454 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 16 16 0,000 9,734E-03 0,0160771 ! negative regulation of tissue remodeling GO:0034104 16 16 0,000 9,734E-03 0,01606966 ! positive regulation of neurological system process GO:0031646 16 16 0,000 9,734E-03 0,01606224 ! neuromuscular synaptic transmission GO:0007274 16 16 0,000 9,734E-03 0,01605482 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 9,734E-03 0,01604741 ! sperm-egg recognition GO:0035036 17 16 0,000 9,734E-03 0,01604 ! axoneme GO:0005930 16 16 0,000 9,734E-03 0,0160326 ! anion exchanger activity GO:0015380 18 17 0,000 0,01033914 0,01702217 ! neuron maturation GO:0042551 18 17 0,000 0,01033914 0,01701432 ! metencephalon development GO:0022037 18 17 0,000 0,01033914 0,01700649 ! regulation of lipid biosynthetic process GO:0046890 18 17 0,000 0,01033914 0,01699866 ! reciprocal meiotic recombination GO:0007131 17 17 0,000 0,01033914 0,01699083 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 17 17 0,000 0,01033914 0,01698302 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 17 17 0,000 0,01033914 0,01697521 ! protein amino acid deacetylation GO:0006476 17 17 0,000 0,01033914 0,01696741 ! protein amino acid acetylation GO:0006473 19 17 0,000 0,01033914 0,01695962 ! positive regulation of nucleocytoplasmic transport GO:0046824 18 17 0,000 0,01033914 0,01695183 ! regulation of neurotransmitter secretion GO:0046928 18 17 0,000 0,01033914 0,01694405 ! striated muscle thick filament GO:0005863 19 17 0,000 0,01033914 0,01693628 GO:0032982|myosin filament, ! gamma-aminobutyric acid signaling pathway GO:0007214 17 17 0,000 0,01033914 0,01692851 ! glial cell development GO:0021782 17 17 0,000 0,01033914 0,01692075 ! regulation of muscle cell differentiation GO:0051147 17 17 0,000 0,01033914 0,016913 ! pancreas development GO:0031016 17 17 0,000 0,01033914 0,01690526 ! acetylcholine receptor activity GO:0015464 17 17 0,000 0,01033914 0,01689752 ! nuclear heterochromatin GO:0005720 18 17 0,000 0,01033914 0,01688979 ! calcium-dependent protein binding GO:0048306 19 17 0,000 0,01033914 0,01688207 ! cerebral cortex development GO:0021987 17 17 0,000 0,01033914 0,01687435 ! cellular response to starvation GO:0009267 18 17 0,000 0,01033914 0,01686664 ! signal sequence binding GO:0005048 17 17 0,000 0,01033914 0,01685894 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 17 17 0,000 0,01033914 0,01685125 ! cellular macromolecular complex disassembly GO:0034623 18 17 0,000 0,01033914 0,01684356 ! transforming growth factor beta receptor activity GO:0005024 17 17 0,000 0,01033914 0,01683588 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,01033914 0,01682821 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 17 17 0,000 0,01033914 0,01682054 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 17 0,000 0,01033914 0,01681288 ! actin filament bundle GO:0032432 17 17 0,000 0,01033914 0,01680523 GO:0001725|stress fiber, ! small nucleolar ribonucleoprotein complex GO:0005732 17 17 0,000 0,01033914 0,01679758 ! response to lipopolysaccharide GO:0032496 17 17 0,000 0,01033914 0,01678994 ! plasma membrane fusion GO:0045026 18 17 0,000 0,01033914 0,01678231 ! regulation of protein binding GO:0043393 18 17 0,000 0,01033914 0,01677469 ! recycling endosome GO:0055037 18 17 0,000 0,01033914 0,01676707 ! prostaglandin metabolic process GO:0006693 18 17 0,000 0,01033914 0,01675946 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 19 17 0,000 0,01033914 0,01675185 ! regulation of Rho GTPase activity GO:0032319 17 17 0,000 0,01033914 0,01674426 ! regulation of immunoglobulin mediated immune response GO:0002889 21 17 0,000 0,01033914 0,01673666 GO:0002712|regulation of B cell mediated immunity, ! receptor signaling complex scaffold activity GO:0030159 17 17 0,000 0,01033914 0,01672908 ! positive regulation of cytokine secretion GO:0050715 17 17 0,000 0,01033914 0,0167215 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 17 0,000 0,01033914 0,01671394 ! endodeoxyribonuclease activity GO:0004520 17 17 0,000 0,01033914 0,01670637 ! sphingolipid catabolic process GO:0030149 18 17 0,000 0,01033914 0,01669882 ! steroid catabolic process GO:0006706 17 17 0,000 0,01033914 0,01669127 ! phosphatidylinositol binding GO:0005545 19 17 0,000 0,01033914 0,01668372 ! hyaluronic acid binding GO:0005540 17 17 0,000 0,01033914 0,01667619 ! regulation of glucose metabolic process GO:0010906 17 17 0,000 0,01033914 0,01666866 ! G2/M transition of mitotic cell cycle GO:0000086 17 17 0,000 0,01033914 0,01666114 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 17 17 0,000 0,01033914 0,01665362 ! glycosaminoglycan biosynthetic process GO:0006024 17 17 0,000 0,01033914 0,01664611 ! MAP kinase kinase kinase activity GO:0004709 18 17 0,000 0,01033914 0,01663861 ! L-ascorbic acid binding GO:0031418 17 17 0,000 0,01033914 0,01663112 ! negative regulation of endothelial cell proliferation GO:0001937 17 17 0,000 0,01033914 0,01662363 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 18 17 0,000 0,01033914 0,01661615 ! photoreceptor cell maintenance GO:0045494 17 17 0,000 0,01033914 0,01660867 ! response to carbohydrate stimulus GO:0009743 17 17 0,000 0,01033914 0,01660121 ! calmodulin-dependent protein kinase activity GO:0004683 19 17 0,000 0,01033914 0,01659375 ! fucose metabolic process GO:0006004 19 17 0,000 0,01033914 0,01658629 ! D-ribose metabolic process GO:0006014 18 17 0,000 0,01033914 0,01657884 ! membrane budding GO:0006900 18 17 0,000 0,01033914 0,0165714 ! AMP binding GO:0016208 17 17 0,000 0,01033914 0,01656397 ! nuclear ubiquitin ligase complex GO:0000152 17 17 0,000 0,01033914 0,01655654 ! body fluid secretion GO:0007589 18 17 0,000 0,01033914 0,01654912 ! response to fungus GO:0009620 17 17 0,000 0,01033914 0,0165417 ! positive regulation of alpha-beta T cell activation GO:0046635 21 17 0,000 0,01033914 0,0165343 ! intermediate filament-based process GO:0045103 18 17 0,000 0,01033914 0,01652689 ! rRNA binding GO:0019843 17 17 0,000 0,01033914 0,0165195 ! regulation of interleukin-2 production GO:0032663 17 17 0,000 0,01033914 0,01651211 ! voltage-gated chloride channel activity GO:0005247 17 17 0,000 0,01033914 0,01650473 ! neutrophil chemotaxis GO:0030593 18 17 0,000 0,01033914 0,01649736 ! long-chain fatty acid transport GO:0015909 17 17 0,000 0,01033914 0,01648999 ! tissue regeneration GO:0042246 17 17 0,000 0,01033914 0,01648263 ! detection of biotic stimulus GO:0009595 18 17 0,000 0,01033914 0,01647527 ! muscle maintenance GO:0046716 18 17 0,000 0,01033914 0,01646792 ! cell-cell junction organization GO:0045216 17 17 0,000 0,01033914 0,01646058 ! somatic recombination of immunoglobulin gene segments GO:0016447 17 17 0,000 0,01033914 0,01645325 ! cell-cell adherens junction GO:0005913 17 17 0,000 0,01033914 0,01644592 ! triacylglycerol lipase activity GO:0004806 17 17 0,000 0,01033914 0,01643859 ! ATP-dependent DNA helicase activity GO:0004003 17 17 0,000 0,01033914 0,01643128 ! chaperone binding GO:0051087 18 18 0,000 0,01094436 0,01738537 ! positive regulation of ossification GO:0045778 19 18 0,000 0,01094436 0,01737764 ! pteridine and derivative metabolic process GO:0042558 19 18 0,000 0,01094436 0,01736991 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,01094436 0,0173622 GO:0005763|mitochondrial small ribosomal subunit, ! signal complex assembly GO:0007172 18 18 0,000 0,01094436 0,01735449 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 19 18 0,000 0,01094436 0,01734678 ! limbic system development GO:0021761 18 18 0,000 0,01094436 0,01733909 ! cellular response to hydrogen peroxide GO:0070301 18 18 0,000 0,01094436 0,0173314 GO:0042744|hydrogen peroxide catabolic process, ! MHC class II protein complex GO:0042613 18 18 0,000 0,01094436 0,01732372 ! positive regulation of proteolysis GO:0045862 19 18 0,000 0,01094436 0,01731604 ! deoxyribonucleotide metabolic process GO:0009262 19 18 0,000 0,01094436 0,01730837 ! lysosome organization GO:0007040 18 18 0,000 0,01094436 0,01730071 ! central nervous system neuron development GO:0021954 19 18 0,000 0,01094436 0,01729306 ! fatty acid beta-oxidation GO:0006635 18 18 0,000 0,01094436 0,01728541 ! regulation of viral reproduction GO:0050792 18 18 0,000 0,01094436 0,01727777 ! peptide cross-linking GO:0018149 20 18 0,000 0,01094436 0,01727013 ! ventricular cardiac muscle morphogenesis GO:0055010 19 18 0,000 0,01094436 0,0172625 ! presynaptic membrane GO:0042734 19 18 0,000 0,01094436 0,01725488 ! embryonic digit morphogenesis GO:0042733 20 18 0,000 0,01094436 0,01724727 ! neural crest cell migration GO:0001755 18 18 0,000 0,01094436 0,01723966 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,01094436 0,01723206 ! positive regulation of adaptive immune response GO:0002821 22 18 0,000 0,01094436 0,01722446 ! positive regulation of intracellular transport GO:0032388 19 18 0,000 0,01094436 0,01721687 ! negative regulation of intracellular transport GO:0032387 18 18 0,000 0,01094436 0,01720929 ! peptidyl-serine modification GO:0018209 18 18 0,000 0,01094436 0,01720172 ! cell-cell recognition GO:0009988 19 18 0,000 0,01094436 0,01719415 ! vitamin D receptor binding GO:0042809 19 18 0,000 0,01094436 0,01718659 ! porphyrin biosynthetic process GO:0006779 18 18 0,000 0,01094436 0,01717904 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 18 0,000 0,01094436 0,01717149 ! actin filament-based movement GO:0030048 18 18 0,000 0,01094436 0,01716395 ! negative regulation of translation GO:0017148 20 18 0,000 0,01094436 0,01715641 ! Rab GTPase binding GO:0017137 18 18 0,000 0,01094436 0,01714888 ! histone deacetylase activity GO:0004407 19 18 0,000 0,01094436 0,01714136 GO:0033558|protein deacetylase activity, ! protein import into nucleus, docking GO:0000059 18 18 0,000 0,01094436 0,01713385 ! negative regulation of cell cycle process GO:0010948 18 18 0,000 0,01094436 0,01712634 ! glycerol metabolic process GO:0006071 19 18 0,000 0,01094436 0,01711884 ! post-Golgi vesicle-mediated transport GO:0006892 18 18 0,000 0,01094436 0,01711134 ! intra-Golgi vesicle-mediated transport GO:0006891 18 18 0,000 0,01094436 0,01710385 ! aminoglycan catabolic process GO:0006026 18 18 0,000 0,01094436 0,01709637 ! aminoglycan biosynthetic process GO:0006023 18 18 0,000 0,01094436 0,0170889 ! small conjugating protein binding GO:0032182 18 18 0,000 0,01094436 0,01708143 ! memory GO:0007613 19 18 0,000 0,01094436 0,01707396 ! C21-steroid hormone metabolic process GO:0008207 18 18 0,000 0,01094436 0,01706651 ! regulation of DNA recombination GO:0000018 22 18 0,000 0,01094436 0,01705906 ! protein phosphatase type 2A complex GO:0000159 20 18 0,000 0,01094436 0,01705162 ! inactivation of MAPK activity GO:0000188 19 18 0,000 0,01094436 0,01704418 ! pigmentation during development GO:0048066 21 18 0,000 0,01094436 0,01703675 ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 18 0,000 0,01094436 0,01702933 ! acetylcholine binding GO:0042166 19 18 0,000 0,01094436 0,01702191 ! neurotransmitter:sodium symporter activity GO:0005328 18 18 0,000 0,01094436 0,0170145 ! neurotransmitter metabolic process GO:0042133 23 18 0,000 0,01094436 0,0170071 ! neuromuscular junction development GO:0007528 21 18 0,000 0,01094436 0,0169997 ! nonmotile primary cilium GO:0031513 19 18 0,000 0,01094436 0,01699231 ! coreceptor activity GO:0015026 18 18 0,000 0,01094436 0,01698492 ! behavioral interaction between organisms GO:0051705 18 18 0,000 0,01094436 0,01697754 ! carbonate dehydratase activity GO:0004089 19 18 0,000 0,01094436 0,01697017 ! cytolysis GO:0019835 18 18 0,000 0,01094436 0,01696281 ! phosphate binding GO:0042301 19 18 0,000 0,01094436 0,01695545 ! transport vesicle membrane GO:0030658 21 18 0,000 0,01094436 0,01694809 ! specific transcriptional repressor activity GO:0016566 18 18 0,000 0,01094436 0,01694075 ! DNA modification GO:0006304 20 18 0,000 0,01094436 0,01693341 ! bicarbonate transmembrane transporter activity GO:0015106 19 18 0,000 0,01094436 0,01692607 ! detection of chemical stimulus GO:0009593 19 18 0,000 0,01094436 0,01691875 ! ionotropic glutamate receptor activity GO:0004970 20 18 0,000 0,01094436 0,01691143 ! aspartic-type endopeptidase activity GO:0004190 19 18 0,000 0,01094436 0,01690411 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 18 18 0,000 0,01094436 0,0168968 ! 3'-5' exonuclease activity GO:0008408 18 18 0,000 0,01094436 0,0168895 ! RNA polymerase II transcription mediator activity GO:0016455 19 18 0,000 0,01094436 0,01688221 ! water-soluble vitamin biosynthetic process GO:0042364 19 18 0,000 0,01094436 0,01687492 ! connexon complex GO:0005922 18 18 0,000 0,01094436 0,01686763 ! solute:hydrogen antiporter activity GO:0015299 18 18 0,000 0,01094436 0,01686036 ! mRNA export from nucleus GO:0006406 21 19 0,000 0,01154924 0,01778454 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 20 19 0,000 0,01154924 0,01777688 ! regulation of interferon-gamma production GO:0032649 20 19 0,000 0,01154924 0,01776922 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 20 19 0,000 0,01154924 0,01776156 ! anion:anion antiporter activity GO:0015301 20 19 0,000 0,01154924 0,01775392 ! cAMP metabolic process GO:0046058 19 19 0,000 0,01154924 0,01774628 ! spindle microtubule GO:0005876 20 19 0,000 0,01154924 0,01773865 ! ovarian follicle development GO:0001541 19 19 0,000 0,01154924 0,01773102 ! retinoid metabolic process GO:0001523 19 19 0,000 0,01154924 0,0177234 GO:0016101|diterpenoid metabolic process, ! caspase activator activity GO:0008656 19 19 0,000 0,01154924 0,01771579 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 21 19 0,000 0,01154924 0,01770818 ! vacuolar transport GO:0007034 19 19 0,000 0,01154924 0,01770058 ! threonine-type endopeptidase activity GO:0004298 19 19 0,000 0,01154924 0,01769299 GO:0070003|threonine-type peptidase activity, ! myofibril assembly GO:0030239 19 19 0,000 0,01154924 0,0176854 GO:0055002|striated muscle cell development, ! monocarboxylic acid transmembrane transporter activity GO:0008028 20 19 0,000 0,01154924 0,01767782 ! positive regulation of multicellular organism growth GO:0040018 19 19 0,000 0,01154924 0,01767025 ! cell projection membrane GO:0031253 20 19 0,000 0,01154924 0,01766268 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,01154924 0,01765512 ! transcriptional repressor complex GO:0017053 19 19 0,000 0,01154924 0,01764756 ! vitamin A metabolic process GO:0006776 19 19 0,000 0,01154924 0,01764001 ! positive regulation of myeloid cell differentiation GO:0045639 20 19 0,000 0,01154924 0,01763247 ! negative regulation of myeloid cell differentiation GO:0045638 19 19 0,000 0,01154924 0,01762494 ! glutamine family amino acid catabolic process GO:0009065 21 19 0,000 0,01154924 0,01761741 ! leukotriene biosynthetic process GO:0019370 19 19 0,000 0,01154924 0,01760989 GO:0043450|alkene biosynthetic process, ! retinoid binding GO:0005501 19 19 0,000 0,01154924 0,01760237 GO:0019840|isoprenoid binding, ! peptide hormone secretion GO:0030072 20 19 0,000 0,01154924 0,01759486 ! protein stabilization GO:0050821 20 19 0,000 0,01154924 0,01758736 ! myeloid leukocyte differentiation GO:0002573 21 19 0,000 0,01154924 0,01757986 ! microtubule-based transport GO:0010970 19 19 0,000 0,01154924 0,01757237 ! protein complex scaffold GO:0032947 19 19 0,000 0,01154924 0,01756489 ! SNAP receptor activity GO:0005484 21 19 0,000 0,01154924 0,01755741 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,01154924 0,01754994 GO:0006479|protein amino acid methylation, ! regulation of systemic arterial blood pressure by hormone GO:0001990 19 19 0,000 0,01154924 0,01754247 GO:0050886|endocrine process, ! visual behavior GO:0007632 22 19 0,000 0,01154924 0,01753501 GO:0008542|visual learning, ! 4 iron, 4 sulfur cluster binding GO:0051539 21 19 0,000 0,01154924 0,01752756 ! glycoprotein binding GO:0001948 23 19 0,000 0,01154924 0,01752012 ! sensory perception of taste GO:0050909 19 19 0,000 0,01154924 0,01751268 ! myoblast differentiation GO:0045445 19 19 0,000 0,01154924 0,01750524 ! cell differentiation in spinal cord GO:0021515 19 19 0,000 0,01154924 0,01749782 ! immune response-activating cell surface receptor signaling pathway GO:0002429 25 19 0,000 0,01154924 0,0174904 ! myosin binding GO:0017022 19 19 0,000 0,01154924 0,01748298 ! organic acid:sodium symporter activity GO:0005343 19 19 0,000 0,01154924 0,01747557 ! cell aging GO:0007569 19 19 0,000 0,01154924 0,01746817 ! stem cell differentiation GO:0048863 19 19 0,000 0,01154924 0,01746078 ! regulation of myeloid leukocyte differentiation GO:0002761 21 19 0,000 0,01154924 0,01745339 ! heart process GO:0003015 20 19 0,000 0,01154924 0,017446 GO:0060047|heart contraction, ! mismatch repair GO:0006298 19 19 0,000 0,01154924 0,01743863 ! secretory granule membrane GO:0030667 20 19 0,000 0,01154924 0,01743126 ! MHC protein binding GO:0042287 19 19 0,000 0,01154924 0,01742389 ! extracellular-glutamate-gated ion channel activity GO:0005234 21 19 0,000 0,01154924 0,01741653 ! chloride transmembrane transporter activity GO:0015108 20 19 0,000 0,01154924 0,01740918 ! GABA-A receptor activity GO:0004890 20 19 0,000 0,01154924 0,01740184 ! response to cytokine stimulus GO:0034097 20 19 0,000 0,01154924 0,0173945 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,01154924 0,01738716 ! translation elongation factor activity GO:0003746 22 19 0,000 0,01154924 0,01737984 ! insulin receptor binding GO:0005158 20 19 0,000 0,01154924 0,01737252 ! phosphoprotein phosphatase inhibitor activity GO:0004864 21 19 0,000 0,01154924 0,0173652 ! protein secretion GO:0009306 20 20 0,000 0,0121538 0,01826651 ! positive regulation of angiogenesis GO:0045766 22 20 0,000 0,0121538 0,01825882 ! proteasome core complex GO:0005839 20 20 0,000 0,0121538 0,01825115 ! positive regulation of bone remodeling GO:0046852 21 20 0,000 0,0121538 0,01824347 ! heterophilic cell adhesion GO:0007157 21 20 0,000 0,0121538 0,01823581 ! glutathione transferase activity GO:0004364 20 20 0,000 0,0121538 0,01822815 ! microtubule organizing center organization GO:0031023 20 20 0,000 0,0121538 0,0182205 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 20 20 0,000 0,0121538 0,01821285 ! actomyosin GO:0042641 20 20 0,000 0,0121538 0,01820521 ! positive regulation of innate immune response GO:0045089 20 20 0,000 0,0121538 0,01819758 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 20 0,000 0,0121538 0,01818995 ! vacuole organization GO:0007033 20 20 0,000 0,0121538 0,01818233 ! oxidoreductase activity, acting on heme group of donors GO:0016675 21 20 0,000 0,0121538 0,01817472 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! purine ribonucleoside metabolic process GO:0046128 23 20 0,000 0,0121538 0,01816711 GO:0042278|purine nucleoside metabolic process, ! chromosome condensation GO:0030261 20 20 0,000 0,0121538 0,01815951 ! regulation of exocytosis GO:0017157 21 20 0,000 0,0121538 0,01815191 ! vitamin biosynthetic process GO:0009110 21 20 0,000 0,0121538 0,01814433 ! glycosphingolipid metabolic process GO:0006687 20 20 0,000 0,0121538 0,01813674 ! kinase activator activity GO:0019209 20 20 0,000 0,0121538 0,01812917 ! diencephalon development GO:0021536 20 20 0,000 0,0121538 0,0181216 ! positive regulation of locomotion GO:0040017 20 20 0,000 0,0121538 0,01811403 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! synaptic vesicle transport GO:0048489 21 20 0,000 0,0121538 0,01810648 ! proteoglycan biosynthetic process GO:0030166 20 20 0,000 0,0121538 0,01809893 ! negative regulation of Wnt receptor signaling pathway GO:0030178 21 20 0,000 0,0121538 0,01809138 ! regulation of blood coagulation GO:0030193 22 20 0,000 0,0121538 0,01808384 ! positive regulation of osteoblast differentiation GO:0045669 22 20 0,000 0,0121538 0,01807631 ! regulation of generation of precursor metabolites and energy GO:0043467 21 20 0,000 0,0121538 0,01806879 ! ligase activity, forming carbon-sulfur bonds GO:0016877 20 20 0,000 0,0121538 0,01806127 ! phosphorus-oxygen lyase activity GO:0016849 20 20 0,000 0,0121538 0,01805375 ! alditol metabolic process GO:0019400 21 20 0,000 0,0121538 0,01804625 ! chromosome, telomeric region GO:0000781 21 20 0,000 0,0121538 0,01803875 ! calcium-independent cell-cell adhesion GO:0016338 20 20 0,000 0,0121538 0,01803125 ! response to alkaloid GO:0043279 22 20 0,000 0,0121538 0,01802376 ! regulation of cell-matrix adhesion GO:0001952 22 20 0,000 0,0121538 0,01801628 GO:0010810|regulation of cell-substrate adhesion, ! transmembrane receptor protein phosphatase activity GO:0019198 27 20 0,000 0,0121538 0,01800881 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! smooth muscle contraction GO:0006939 21 20 0,000 0,0121538 0,01800134 ! heme metabolic process GO:0042168 22 20 0,000 0,0121538 0,01799387 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 20 20 0,000 0,0121538 0,01798642 ! sex determination GO:0007530 20 20 0,000 0,0121538 0,01797897 ! negative regulation of protein catabolic process GO:0042177 21 20 0,000 0,0121538 0,01797152 ! peptide secretion GO:0002790 21 20 0,000 0,0121538 0,01796408 ! regulation of alpha-beta T cell activation GO:0046634 24 20 0,000 0,0121538 0,01795665 ! interaction with host GO:0051701 24 20 0,000 0,0121538 0,01794922 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 26 20 0,000 0,0121538 0,0179418 ! vasodilation GO:0042311 21 20 0,000 0,0121538 0,01793439 ! regulation of tumor necrosis factor production GO:0032680 20 20 0,000 0,0121538 0,01792698 ! regulation of chromosome organization GO:0033044 20 20 0,000 0,0121538 0,01791958 ! inward rectifier potassium channel activity GO:0005242 20 20 0,000 0,0121538 0,01791219 ! activation of JUN kinase activity GO:0007257 20 20 0,000 0,0121538 0,0179048 ! cyclic nucleotide binding GO:0030551 22 20 0,000 0,0121538 0,01789741 ! somatic diversification of immunoglobulins GO:0016445 20 20 0,000 0,0121538 0,01789004 ! microvillus GO:0005902 20 20 0,000 0,0121538 0,01788266 ! tumor necrosis factor receptor binding GO:0005164 20 20 0,000 0,0121538 0,0178753 ! ATP-dependent RNA helicase activity GO:0004004 20 20 0,000 0,0121538 0,01786794 ! positive regulation of protein catabolic process GO:0045732 22 21 0,000 0,01275803 0,01874853 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 22 21 0,000 0,01275803 0,01874082 ! growth cone GO:0030426 22 21 0,000 0,01275803 0,01873311 ! oligosaccharide metabolic process GO:0009311 23 21 0,000 0,01275803 0,01872541 ! regulation of anti-apoptosis GO:0045767 21 21 0,000 0,01275803 0,01871772 ! hormone secretion GO:0046879 22 21 0,000 0,01275803 0,01871003 ! protein amino acid O-linked glycosylation GO:0006493 22 21 0,000 0,01275803 0,01870235 ! transition metal ion transmembrane transporter activity GO:0046915 21 21 0,000 0,01275803 0,01869468 ! voltage-gated calcium channel complex GO:0005891 24 21 0,000 0,01275803 0,01868701 GO:0034704|calcium channel complex, ! dicarboxylic acid metabolic process GO:0043648 22 21 0,000 0,01275803 0,01867935 ! protein phosphatase type 2A regulator activity GO:0008601 23 21 0,000 0,01275803 0,01867169 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 24 21 0,000 0,01275803 0,01866404 ! histone-lysine N-methyltransferase activity GO:0018024 23 21 0,000 0,01275803 0,0186564 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! activation of pro-apoptotic gene products GO:0008633 22 21 0,000 0,01275803 0,01864876 ! mitochondrial membrane organization GO:0007006 22 21 0,000 0,01275803 0,01864113 ! central nervous system neuron differentiation GO:0021953 22 21 0,000 0,01275803 0,01863351 ! Golgi stack GO:0005795 25 21 0,000 0,01275803 0,01862589 ! regulation of endothelial cell migration GO:0010594 21 21 0,000 0,01275803 0,01861828 ! muscle cell development GO:0055001 21 21 0,000 0,01275803 0,01861067 ! cholesterol biosynthetic process GO:0006695 22 21 0,000 0,01275803 0,01860307 ! regulation of vasoconstriction GO:0019229 22 21 0,000 0,01275803 0,01859548 ! deacetylase activity GO:0019213 22 21 0,000 0,01275803 0,01858789 ! phosphatase inhibitor activity GO:0019212 23 21 0,000 0,01275803 0,01858031 ! regulation of fatty acid metabolic process GO:0019217 22 21 0,000 0,01275803 0,01857274 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,01275803 0,01856517 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! sensory perception of pain GO:0019233 21 21 0,000 0,01275803 0,01855761 ! pentose metabolic process GO:0019321 22 21 0,000 0,01275803 0,01855005 ! collagen fibril organization GO:0030199 22 21 0,000 0,01275803 0,0185425 ! platelet activation GO:0030168 23 21 0,000 0,01275803 0,01853496 ! response to glucocorticoid stimulus GO:0051384 22 21 0,000 0,01275803 0,01852742 ! trans-Golgi network transport vesicle GO:0030140 24 21 0,000 0,01275803 0,01851989 ! glutathione metabolic process GO:0006749 21 21 0,000 0,01275803 0,01851236 ! DNA-directed RNA polymerase complex GO:0000428 22 21 0,000 0,01275803 0,01850484 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! terpenoid metabolic process GO:0006721 21 21 0,000 0,01275803 0,01849733 ! cyclase activity GO:0009975 21 21 0,000 0,01275803 0,01848982 ! intramolecular transferase activity GO:0016866 22 21 0,000 0,01275803 0,01848232 ! negative regulation of cytokine production GO:0001818 21 21 0,000 0,01275803 0,01847483 ! fatty acid binding GO:0005504 21 21 0,000 0,01275803 0,01846734 ! gut development GO:0048565 21 21 0,000 0,01275803 0,01845986 ! acetyl-CoA catabolic process GO:0046356 21 21 0,000 0,01275803 0,01845238 GO:0006099|tricarboxylic acid cycle, ! phosphoinositide phospholipase C activity GO:0004435 21 21 0,000 0,01275803 0,01844491 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! protein tetramerization GO:0051262 22 21 0,000 0,01275803 0,01843744 ! regulation of microtubule polymerization or depolymerization GO:0031110 23 21 0,000 0,01275803 0,01842999 ! positive regulation of fibroblast proliferation GO:0048146 22 21 0,000 0,01275803 0,01842253 ! sulfur amino acid metabolic process GO:0000096 22 21 0,000 0,01275803 0,01841509 ! voltage-gated anion channel activity GO:0008308 21 21 0,000 0,01275803 0,01840765 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,01275803 0,01840021 ! cellular polysaccharide biosynthetic process GO:0033692 21 21 0,000 0,01275803 0,01839278 ! positive regulation of JAK-STAT cascade GO:0046427 22 21 0,000 0,01275803 0,01838536 ! sterol binding GO:0032934 21 21 0,000 0,01275803 0,01837794 ! regulation of chemotaxis GO:0050920 21 21 0,000 0,01275803 0,01837053 ! regulation of carbohydrate metabolic process GO:0006109 22 21 0,000 0,01275803 0,01836313 GO:0010675|regulation of cellular carbohydrate metabolic process, ! calcium-dependent cell-cell adhesion GO:0016339 21 21 0,000 0,01275803 0,01835573 ! phosphatase binding GO:0019902 22 21 0,000 0,01275803 0,01834834 ! NAD+ ADP-ribosyltransferase activity GO:0003950 21 21 0,000 0,01275803 0,01834095 ! positive regulation of cytoskeleton organization GO:0051495 21 21 0,000 0,01275803 0,01833357 ! negative regulation of DNA replication GO:0008156 25 21 0,000 0,01275803 0,0183262 ! vesicle targeting GO:0006903 22 21 0,000 0,01275803 0,01831883 ! vesicle docking during exocytosis GO:0006904 21 21 0,000 0,01275803 0,01831147 ! RNA-dependent ATPase activity GO:0008186 21 21 0,000 0,01275803 0,01830411 ! renal system process GO:0003014 22 21 0,000 0,01275803 0,01829676 ! positive regulation of leukocyte mediated immunity GO:0002705 25 21 0,000 0,01275803 0,01828941 GO:0002708|positive regulation of lymphocyte mediated immunity, ! nuclear-transcribed mRNA catabolic process GO:0000956 22 21 0,000 0,01275803 0,01828207 ! apoptotic protease activator activity GO:0016505 21 21 0,000 0,01275803 0,01827474 ! fatty acid transport GO:0015908 21 21 0,000 0,01275803 0,01826741 ! sarcoplasmic reticulum GO:0016529 22 21 0,000 0,01275803 0,01826009 ! positive regulation of tissue remodeling GO:0034105 22 21 0,000 0,01275803 0,01825277 ! collagen catabolic process GO:0030574 21 21 0,000 0,01275803 0,01824546 ! pyrimidine nucleotide biosynthetic process GO:0006221 25 21 0,000 0,01275803 0,01823816 ! regulation of multi-organism process GO:0043900 21 21 0,000 0,01275803 0,01823086 ! ubiquitin-specific protease activity GO:0004843 22 21 0,000 0,01275803 0,01822357 ! positive regulation of DNA replication GO:0045740 23 22 0,000 0,01336193 0,01907855 ! site of polarized growth GO:0030427 23 22 0,000 0,01336193 0,01907092 ! positive regulation of cell adhesion GO:0045785 23 22 0,000 0,01336193 0,0190633 ! leukocyte adhesion GO:0007159 27 22 0,000 0,01336193 0,01905569 ! glutamate signaling pathway GO:0007215 25 22 0,000 0,01336193 0,01904808 ! potassium channel regulator activity GO:0015459 24 22 0,000 0,01336193 0,01904048 ! peroxisome organization GO:0007031 22 22 0,000 0,01336193 0,01903289 ! cellular response to reactive oxygen species GO:0034614 22 22 0,000 0,01336193 0,0190253 ! polysaccharide catabolic process GO:0000272 22 22 0,000 0,01336193 0,01901772 ! response to starvation GO:0042594 23 22 0,000 0,01336193 0,01901014 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 22 22 0,000 0,01336193 0,01900257 ! coenzyme catabolic process GO:0009109 22 22 0,000 0,01336193 0,018995 ! regulation of insulin secretion GO:0050796 23 22 0,000 0,01336193 0,01898745 ! membrane depolarization GO:0051899 24 22 0,000 0,01336193 0,01897989 ! somitogenesis GO:0001756 23 22 0,000 0,01336193 0,01897235 ! regulation of cytokine secretion GO:0050707 22 22 0,000 0,01336193 0,01896481 ! natural killer cell activation GO:0030101 22 22 0,000 0,01336193 0,01895727 ! positive regulation of B cell activation GO:0050871 26 22 0,000 0,01336193 0,01894974 ! aromatic amino acid family metabolic process GO:0009072 25 22 0,000 0,01336193 0,01894222 ! basal plasma membrane GO:0009925 22 22 0,000 0,01336193 0,0189347 GO:0045178|basal part of cell, ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 22 22 0,000 0,01336193 0,01892719 ! telomere organization GO:0032200 23 22 0,000 0,01336193 0,01891969 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 24 22 0,000 0,01336193 0,01891219 GO:0060606|tube closure, ! response to molecule of bacterial origin GO:0002237 22 22 0,000 0,01336193 0,0189047 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 22 0,000 0,01336193 0,01889721 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 22 22 0,000 0,01336193 0,01888973 GO:0016444|somatic cell DNA recombination, ! cortical actin cytoskeleton GO:0030864 22 22 0,000 0,01336193 0,01888225 ! initiation of viral infection GO:0019059 22 22 0,000 0,01336193 0,01887478 ! RNA polymerase complex GO:0030880 23 22 0,000 0,01336193 0,01886732 ! regulation of neurotransmitter transport GO:0051588 23 22 0,000 0,01336193 0,01885986 ! macromolecular complex disassembly GO:0032984 23 22 0,000 0,01336193 0,01885241 ! response to ethanol GO:0045471 25 22 0,000 0,01336193 0,01884497 ! syntaxin binding GO:0019905 23 22 0,000 0,01336193 0,01883753 ! regulation of nitric oxide biosynthetic process GO:0045428 22 22 0,000 0,01336193 0,01883009 ! digestive system process GO:0022600 24 22 0,000 0,01336193 0,01882266 ! neurotransmitter transporter activity GO:0005326 22 22 0,000 0,01336193 0,01881524 ! autophagy GO:0006914 24 22 0,000 0,01336193 0,01880782 ! carbohydrate kinase activity GO:0019200 22 22 0,000 0,01336193 0,01880041 ! neuropeptide hormone activity GO:0005184 23 22 0,000 0,01336193 0,01879301 ! negative regulation of phosphorylation GO:0042326 26 22 0,000 0,01336193 0,01878561 ! transaminase activity GO:0008483 23 22 0,000 0,01336193 0,01877822 ! sarcoplasm GO:0016528 23 22 0,000 0,01336193 0,01877083 ! metallocarboxypeptidase activity GO:0004181 23 22 0,000 0,01336193 0,01876345 ! cellular response to nutrient levels GO:0031669 23 22 0,000 0,01336193 0,01875607 ! positive regulation of nuclear division GO:0051785 22 22 0,000 0,01336193 0,0187487 GO:0045840|positive regulation of mitosis, ! nerve-nerve synaptic transmission GO:0007270 25 22 0,000 0,01336193 0,01874134 ! small conjugating protein-specific protease activity GO:0019783 24 22 0,000 0,01336193 0,01873398 ! pyrimidine nucleoside metabolic process GO:0006213 25 22 0,000 0,01336193 0,01872663 ! solute:cation antiporter activity GO:0015298 22 22 0,000 0,01336193 0,01871928 ! translational initiation GO:0006413 23 23 0,000 0,0139655 0,01955718 ! NF-kappaB binding GO:0051059 23 23 0,000 0,0139655 0,01954951 ! vesicle docking GO:0048278 23 23 0,000 0,0139655 0,01954185 ! muscle myosin complex GO:0005859 25 23 0,000 0,0139655 0,0195342 ! vasculogenesis GO:0001570 25 23 0,000 0,0139655 0,01952655 ! regulation of innate immune response GO:0045088 23 23 0,000 0,0139655 0,01951891 ! androgen receptor binding GO:0050681 23 23 0,000 0,0139655 0,01951127 ! positive regulation of epithelial cell proliferation GO:0050679 24 23 0,000 0,0139655 0,01950364 ! sperm motility GO:0030317 23 23 0,000 0,0139655 0,01949601 ! response to corticosteroid stimulus GO:0031960 24 23 0,000 0,0139655 0,0194884 ! barbed-end actin filament capping GO:0051016 23 23 0,000 0,0139655 0,01948078 GO:0051693|actin filament capping, ! negative regulation of phosphorus metabolic process GO:0010563 27 23 0,000 0,0139655 0,01947318 GO:0045936|negative regulation of phosphate metabolic process, ! osteoblast differentiation GO:0001649 24 23 0,000 0,0139655 0,01946558 ! regulation of behavior GO:0050795 23 23 0,000 0,0139655 0,01945798 ! cardiac muscle tissue morphogenesis GO:0055008 24 23 0,000 0,0139655 0,01945039 GO:0060415|muscle tissue morphogenesis, ! cyclic nucleotide biosynthetic process GO:0009190 23 23 0,000 0,0139655 0,01944281 ! leukotriene metabolic process GO:0006691 23 23 0,000 0,0139655 0,01943523 ! positive regulation of T cell differentiation GO:0045582 27 23 0,000 0,0139655 0,01942766 ! glycolipid metabolic process GO:0006664 23 23 0,000 0,0139655 0,0194201 ! regulation of ARF GTPase activity GO:0032312 26 23 0,000 0,0139655 0,01941254 ! pallium development GO:0021543 23 23 0,000 0,0139655 0,01940498 ! GABA receptor activity GO:0016917 24 23 0,000 0,0139655 0,01939743 ! positive regulation of MAPKKK cascade GO:0043410 30 23 0,000 0,0139655 0,01938989 ! regulation of response to biotic stimulus GO:0002831 23 23 0,000 0,0139655 0,01938236 ! MHC class II receptor activity GO:0032395 23 23 0,000 0,0139655 0,01937483 ! negative regulation of neuron differentiation GO:0045665 23 23 0,000 0,0139655 0,0193673 ! aspartate family amino acid metabolic process GO:0009066 24 23 0,000 0,0139655 0,01935978 ! cell surface binding GO:0043498 25 23 0,000 0,0139655 0,01935227 ! collagen binding GO:0005518 27 23 0,000 0,0139655 0,01934477 ! insulin-like growth factor binding GO:0005520 23 23 0,000 0,0139655 0,01933726 ! regulation of amine transport GO:0051952 23 23 0,000 0,0139655 0,01932977 ! tissue homeostasis GO:0001894 24 23 0,000 0,0139655 0,01932228 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 25 23 0,000 0,0139655 0,0193148 ! protein import into nucleus, translocation GO:0000060 25 23 0,000 0,0139655 0,01930732 ! gluconeogenesis GO:0006094 24 23 0,000 0,0139655 0,01929985 ! iron ion transport GO:0006826 24 23 0,000 0,0139655 0,01929238 ! nucleotide-excision repair, DNA damage removal GO:0000718 24 23 0,000 0,0139655 0,01928492 ! N-acetylglucosamine metabolic process GO:0006044 23 23 0,000 0,0139655 0,01927747 ! molting cycle process GO:0022404 23 23 0,000 0,0139655 0,01927002 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! circadian rhythm GO:0007623 24 23 0,000 0,0139655 0,01926257 ! tube lumen formation GO:0035148 26 23 0,000 0,0139655 0,01925514 ! insulin receptor signaling pathway GO:0008286 28 23 0,000 0,0139655 0,01924771 ! multicellular organismal response to stress GO:0033555 23 23 0,000 0,0139655 0,01924028 ! immune response-activating signal transduction GO:0002757 29 23 0,000 0,0139655 0,01923286 ! lymphocyte proliferation GO:0046651 29 23 0,000 0,0139655 0,01922545 ! fibroblast growth factor receptor signaling pathway GO:0008543 24 23 0,000 0,0139655 0,01921804 ! regulation of bone mineralization GO:0030500 25 23 0,000 0,0139655 0,01921063 ! brush border GO:0005903 25 23 0,000 0,0139655 0,01920324 ! caveola GO:0005901 24 23 0,000 0,0139655 0,01919584 ! gap junction GO:0005921 23 23 0,000 0,0139655 0,01918846 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 25 24 0,000 0,01456874 0,02000961 ! regulation of transmembrane transport GO:0034762 24 24 0,000 0,01456874 0,02000192 ! heterotrimeric G-protein complex GO:0005834 24 24 0,000 0,01456874 0,01999423 ! protein amino acid acylation GO:0043543 26 24 0,000 0,01456874 0,01998655 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 24 0,000 0,01456874 0,01997887 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 25 24 0,000 0,01456874 0,0199712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,01456874 0,01996354 ! MHC class I protein complex GO:0042612 24 24 0,000 0,01456874 0,01995588 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 24 24 0,000 0,01456874 0,01994823 ! early endosome membrane GO:0031901 26 24 0,000 0,01456874 0,01994059 ! primary neural tube formation GO:0014020 26 24 0,000 0,01456874 0,01993295 ! ARF GTPase activator activity GO:0008060 27 24 0,000 0,01456874 0,01992531 ! immunoglobulin production GO:0002377 28 24 0,000 0,01456874 0,01991768 GO:0002440|production of molecular mediator of immune response, ! lipid kinase activity GO:0001727 26 24 0,000 0,01456874 0,01991006 ! positive regulation of protein secretion GO:0050714 26 24 0,000 0,01456874 0,01990244 ! MHC class I receptor activity GO:0032393 24 24 0,000 0,01456874 0,01989483 ! RNA splicing factor activity, transesterification mechanism GO:0031202 24 24 0,000 0,01456874 0,01988723 ! fat-soluble vitamin metabolic process GO:0006775 24 24 0,000 0,01456874 0,01987963 ! regulation of osteoblast differentiation GO:0045667 27 24 0,000 0,01456874 0,01987203 ! cellular alkene metabolic process GO:0043449 24 24 0,000 0,01456874 0,01986445 ! somatic diversification of immune receptors GO:0002200 24 24 0,000 0,01456874 0,01985687 ! positive regulation of JUN kinase activity GO:0043507 24 24 0,000 0,01456874 0,01984929 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 26 24 0,000 0,01456874 0,01984172 ! Z disc GO:0030018 27 24 0,000 0,01456874 0,01983415 ! regulation of fibroblast proliferation GO:0048145 25 24 0,000 0,01456874 0,0198266 ! neuron fate commitment GO:0048663 24 24 0,000 0,01456874 0,01981904 ! glucosamine metabolic process GO:0006041 24 24 0,000 0,01456874 0,0198115 ! regulation of transcription factor import into nucleus GO:0042990 25 24 0,000 0,01456874 0,01980395 ! glucose transport GO:0015758 24 24 0,000 0,01456874 0,01979642 ! dendrite development GO:0016358 26 24 0,000 0,01456874 0,01978889 ! negative regulation of protein modification process GO:0031400 28 24 0,000 0,01456874 0,01978136 ! catechol metabolic process GO:0009712 27 24 0,000 0,01456874 0,01977385 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! phospholipase A2 activity GO:0004623 26 24 0,000 0,01456874 0,01976633 ! immune response-regulating signal transduction GO:0002764 30 24 0,000 0,01456874 0,01975883 ! regulation of production of molecular mediator of immune response GO:0002700 28 24 0,000 0,01456874 0,01975132 ! DNA-directed DNA polymerase activity GO:0003887 25 24 0,000 0,01456874 0,01974383 ! synaptogenesis GO:0007416 25 24 0,000 0,01456874 0,01973634 ! selenium binding GO:0008430 24 24 0,000 0,01456874 0,01972885 ! leukocyte proliferation GO:0070661 30 24 0,000 0,01456874 0,01972137 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 26 24 0,000 0,01456874 0,0197139 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 25 25 0,000 0,01517166 0,02052197 ! phenol metabolic process GO:0018958 28 25 0,000 0,01517166 0,0205142 ! myelination GO:0042552 26 25 0,000 0,01517166 0,02050643 ! epidermal growth factor receptor signaling pathway GO:0007173 28 25 0,000 0,01517166 0,02049867 ! actin filament GO:0005884 28 25 0,000 0,01517166 0,02049092 ! hexose transport GO:0008645 25 25 0,000 0,01517166 0,02048317 GO:0015749|monosaccharide transport, ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 27 25 0,000 0,01517166 0,02047543 ! PML body GO:0016605 28 25 0,000 0,01517166 0,0204677 ! regulation of cellular ketone metabolic process GO:0010565 26 25 0,000 0,01517166 0,02045997 ! negative regulation of cell development GO:0010721 28 25 0,000 0,01517166 0,02045224 GO:0050768|negative regulation of neurogenesis, ! regulation of biomineral formation GO:0070167 27 25 0,000 0,01517166 0,02044453 ! cell fate determination GO:0001709 25 25 0,000 0,01517166 0,02043681 ! regulation of oxidoreductase activity GO:0051341 25 25 0,000 0,01517166 0,02042911 ! group transfer coenzyme metabolic process GO:0006752 26 25 0,000 0,01517166 0,02042141 ! hormone transport GO:0009914 26 25 0,000 0,01517166 0,02041371 ! neuromuscular process controlling balance GO:0050885 26 25 0,000 0,01517166 0,02040603 ! porphyrin metabolic process GO:0006778 27 25 0,000 0,01517166 0,02039834 GO:0033013|tetrapyrrole metabolic process, ! regulation of JUN kinase activity GO:0043506 25 25 0,000 0,01517166 0,02039066 ! cell adhesion molecule binding GO:0050839 27 25 0,000 0,01517166 0,02038299 ! negative regulation of actin filament depolymerization GO:0030835 25 25 0,000 0,01517166 0,02037533 ! acetyl-CoA metabolic process GO:0006084 25 25 0,000 0,01517166 0,02036767 ! membrane lipid catabolic process GO:0046466 26 25 0,000 0,01517166 0,02036001 ! zinc ion transport GO:0006829 26 25 0,000 0,01517166 0,02035237 ! heterochromatin GO:0000792 26 25 0,000 0,01517166 0,02034472 ! cellular iron ion homeostasis GO:0006879 25 25 0,000 0,01517166 0,02033709 ! phototransduction GO:0007602 25 25 0,000 0,01517166 0,02032945 ! keratinization GO:0031424 26 25 0,000 0,01517166 0,02032183 ! spinal cord development GO:0021510 25 25 0,000 0,01517166 0,02031421 ! cyclin-dependent protein kinase activity GO:0004693 26 25 0,000 0,01517166 0,0203066 ! regulation of smooth muscle contraction GO:0006940 28 25 0,000 0,01517166 0,02029899 ! response to toxin GO:0009636 25 25 0,000 0,01517166 0,02029138 ! regulation of peptide secretion GO:0002791 26 25 0,000 0,01517166 0,02028379 ! determination of left/right symmetry GO:0007368 25 25 0,000 0,01517166 0,0202762 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 25 0,000 0,01517166 0,02026861 ! regulation of interleukin-6 production GO:0032675 25 25 0,000 0,01517166 0,02026103 ! voltage-gated calcium channel activity GO:0005245 28 25 0,000 0,01517166 0,02025346 ! phospholipid transport GO:0015914 26 25 0,000 0,01517166 0,02024589 ! peptidase activator activity GO:0016504 25 25 0,000 0,01517166 0,02023833 ! protein localization in mitochondrion GO:0070585 26 25 0,000 0,01517166 0,02023077 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 25 25 0,000 0,01517166 0,02022322 ! regulation of microtubule cytoskeleton organization GO:0070507 27 25 0,000 0,01517166 0,02021567 ! ethanolamine and derivative metabolic process GO:0042439 28 25 0,000 0,01517166 0,02020813 ! small nuclear ribonucleoprotein complex GO:0030532 25 25 0,000 0,01517166 0,0202006 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 25 25 0,000 0,01517166 0,02019307 ! negative regulation of transcription regulator activity GO:0090048 26 25 0,000 0,01517166 0,02018554 GO:0043433|negative regulation of transcription factor activity, ! acetylgalactosaminyltransferase activity GO:0008376 27 25 0,000 0,01517166 0,02017802 ! solute:solute antiporter activity GO:0015300 26 26 0,000 0,01577425 0,02097164 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 27 26 0,000 0,01577425 0,02096384 ! regeneration GO:0031099 26 26 0,000 0,01577425 0,02095604 ! cholesterol homeostasis GO:0042632 26 26 0,000 0,01577425 0,02094825 GO:0055092|sterol homeostasis, ! peptidyl-tyrosine phosphorylation GO:0018108 27 26 0,000 0,01577425 0,02094046 ! ureteric bud development GO:0001657 26 26 0,000 0,01577425 0,02093268 ! neural crest cell development GO:0014032 26 26 0,000 0,01577425 0,0209249 GO:0014033|neural crest cell differentiation, ! negative regulation of protein kinase cascade GO:0010741 27 26 0,000 0,01577425 0,02091713 ! cellular response to oxidative stress GO:0034599 26 26 0,000 0,01577425 0,02090937 ! lipid oxidation GO:0034440 26 26 0,000 0,01577425 0,02090161 GO:0019395|fatty acid oxidation, ! positive regulation of lymphocyte differentiation GO:0045621 30 26 0,000 0,01577425 0,02089386 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 26 26 0,000 0,01577425 0,02088611 ! carboxy-lyase activity GO:0016831 26 26 0,000 0,01577425 0,02087837 ! myeloid leukocyte activation GO:0002274 27 26 0,000 0,01577425 0,02087063 ! negative regulation of neuron apoptosis GO:0043524 26 26 0,000 0,01577425 0,0208629 ! negative regulation of catabolic process GO:0009895 28 26 0,000 0,01577425 0,02085518 ! lysine N-acetyltransferase activity GO:0004468 26 26 0,000 0,01577425 0,02084746 GO:0004402|histone acetyltransferase activity, ! regulation of actin filament depolymerization GO:0030834 26 26 0,000 0,01577425 0,02083975 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,01577425 0,02083204 ! determination of bilateral symmetry GO:0009855 26 26 0,000 0,01577425 0,02082434 GO:0009799|determination of symmetry, ! regulation of cellular catabolic process GO:0031329 28 26 0,000 0,01577425 0,02081664 ! pyruvate metabolic process GO:0006090 27 26 0,000 0,01577425 0,02080895 ! cellular component assembly involved in morphogenesis GO:0010927 26 26 0,000 0,01577425 0,02080127 ! histone methyltransferase activity GO:0042054 29 26 0,000 0,01577425 0,02079359 ! regulation of endothelial cell proliferation GO:0001936 27 26 0,000 0,01577425 0,02078592 ! receptor metabolic process GO:0043112 28 26 0,000 0,01577425 0,02077825 ! nucleotide kinase activity GO:0019201 30 26 0,000 0,01577425 0,02077059 ! histone deacetylase complex GO:0000118 27 26 0,000 0,01577425 0,02076293 ! phospholipase C activity GO:0004629 27 26 0,000 0,01577425 0,02075528 ! cellular response to extracellular stimulus GO:0031668 27 26 0,000 0,01577425 0,02074764 ! receptor regulator activity GO:0030545 26 26 0,000 0,01577425 0,02074 ! galactosyltransferase activity GO:0008378 27 26 0,000 0,01577425 0,02073236 ! response to heat GO:0009408 26 26 0,000 0,01577425 0,02072474 ! positive regulation of immune effector process GO:0002699 30 26 0,000 0,01577425 0,02071711 ! mRNA catabolic process GO:0006402 28 27 0,000 0,01637651 0,02150019 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 28 27 0,000 0,01637651 0,02149228 ! actomyosin structure organization GO:0031032 28 27 0,000 0,01637651 0,02148439 ! nucleotide receptor activity, G-protein coupled GO:0001608 27 27 0,000 0,01637651 0,0214765 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 28 27 0,000 0,01637651 0,02146861 ! iron ion homeostasis GO:0055072 27 27 0,000 0,01637651 0,02146074 ! lipoprotein binding GO:0008034 29 27 0,000 0,01637651 0,02145286 ! deaminase activity GO:0019239 27 27 0,000 0,01637651 0,021445 ! mesoderm formation GO:0001707 28 27 0,000 0,01637651 0,02143713 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 27 27 0,000 0,01637651 0,02142928 ! phospholipid transporter activity GO:0005548 29 27 0,000 0,01637651 0,02142143 ! neural tube formation GO:0001841 29 27 0,000 0,01637651 0,02141359 ! mitotic sister chromatid segregation GO:0000070 27 27 0,000 0,01637651 0,02140575 ! integrin complex GO:0008305 28 27 0,000 0,01637651 0,02139792 ! nuclear chromatin GO:0000790 28 27 0,000 0,01637651 0,02139009 ! collagen metabolic process GO:0032963 27 27 0,000 0,01637651 0,02138227 ! post-embryonic development GO:0009791 29 27 0,000 0,01637651 0,02137445 ! antigen processing and presentation of peptide antigen GO:0048002 28 27 0,000 0,01637651 0,02136664 ! ovulation cycle process GO:0022602 27 27 0,000 0,01637651 0,02135884 ! SNARE binding GO:0000149 28 27 0,000 0,01637651 0,02135104 ! biogenic amine biosynthetic process GO:0042401 28 27 0,000 0,01637651 0,02134325 ! spindle pole GO:0000922 28 27 0,000 0,01637651 0,02133546 ! anion:cation symporter activity GO:0015296 28 27 0,000 0,01637651 0,02132768 ! trans-Golgi network GO:0005802 29 28 0,000 0,01697844 0,02210354 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 28 0,000 0,01697844 0,02209548 ! cholesterol transport GO:0030301 28 28 0,000 0,01697844 0,02208743 GO:0015918|sterol transport, ! thyroid hormone receptor binding GO:0046966 29 28 0,000 0,01697844 0,02207939 ! dynein complex GO:0030286 29 28 0,000 0,01697844 0,02207135 ! formation of primary germ layer GO:0001704 29 28 0,000 0,01697844 0,02206332 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 30 28 0,000 0,01697844 0,02205529 ! ovulation cycle GO:0042698 28 28 0,000 0,01697844 0,02204727 ! peptidyl-tyrosine modification GO:0018212 29 28 0,000 0,01697844 0,02203926 ! deoxyribonuclease activity GO:0004536 28 28 0,000 0,01697844 0,02203125 ! cofactor catabolic process GO:0051187 30 28 0,000 0,01697844 0,02202325 ! DNA damage checkpoint GO:0000077 31 28 0,000 0,01697844 0,02201525 ! negative regulation of actin filament polymerization GO:0030837 28 28 0,000 0,01697844 0,02200726 ! cortical cytoskeleton GO:0030863 29 28 0,000 0,01697844 0,02199928 ! icosanoid biosynthetic process GO:0046456 29 28 0,000 0,01697844 0,0219913 ! amino sugar metabolic process GO:0006040 28 28 0,000 0,01697844 0,02198332 ! membrane docking GO:0022406 28 28 0,000 0,01697844 0,02197535 ! sister chromatid segregation GO:0000819 28 28 0,000 0,01697844 0,02196739 ! detection of light stimulus involved in sensory perception GO:0050962 28 28 0,000 0,01697844 0,02195944 GO:0050908|detection of light stimulus involved in visual perception, ! cell junction assembly GO:0034329 30 28 0,000 0,01697844 0,02195149 ! complement activation, classical pathway GO:0006958 31 28 0,000 0,01697844 0,02194354 ! multicellular organismal catabolic process GO:0044243 28 28 0,000 0,01697844 0,0219356 ! response to mechanical stimulus GO:0009612 28 28 0,000 0,01697844 0,02192767 ! caspase regulator activity GO:0043028 28 28 0,000 0,01697844 0,02191974 ! ensheathment of neurons GO:0007272 29 28 0,000 0,01697844 0,02191182 GO:0008366|axon ensheathment, ! DNA polymerase activity GO:0034061 29 28 0,000 0,01697844 0,0219039 ! calcium-mediated signaling GO:0019722 28 28 0,000 0,01697844 0,02189599 ! neurotransmitter secretion GO:0007269 29 28 0,000 0,01697844 0,02188809 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 28 28 0,000 0,01697844 0,02188019 ! glycogen metabolic process GO:0005977 29 28 0,000 0,01697844 0,0218723 ! RNA helicase activity GO:0003724 28 28 0,000 0,01697844 0,02186441 ! Rho GTPase activator activity GO:0005100 32 28 0,000 0,01697844 0,02185653 ! symbiosis, encompassing mutualism through parasitism GO:0044403 32 28 0,000 0,01697844 0,02184865 ! transferase activity, transferring nitrogenous groups GO:0016769 30 29 0,000 0,01758004 0,02261467 ! spliceosomal snRNP biogenesis GO:0000387 30 29 0,000 0,01758004 0,02260653 ! odontogenesis of dentine-containing tooth GO:0042475 30 29 0,000 0,01758004 0,02259839 ! scavenger receptor activity GO:0005044 30 29 0,000 0,01758004 0,02259026 ! spindle organization GO:0007051 30 29 0,000 0,01758004 0,02258213 ! mesoderm morphogenesis GO:0048332 30 29 0,000 0,01758004 0,02257401 ! male gonad development GO:0008584 29 29 0,000 0,01758004 0,0225659 ! response to organic cyclic substance GO:0014070 31 29 0,000 0,01758004 0,02255779 ! negative regulation of MAP kinase activity GO:0043407 30 29 0,000 0,01758004 0,02254969 ! sterol biosynthetic process GO:0016126 30 29 0,000 0,01758004 0,02254159 ! endocytic vesicle GO:0030139 29 29 0,000 0,01758004 0,0225335 ! fatty acid catabolic process GO:0009062 30 29 0,000 0,01758004 0,02252541 ! regulation of calcium ion transport GO:0051924 32 29 0,000 0,01758004 0,02251734 ! negative regulation of protein polymerization GO:0032272 29 29 0,000 0,01758004 0,02250926 ! glucan metabolic process GO:0044042 30 29 0,000 0,01758004 0,02250119 GO:0006073|cellular glucan metabolic process, ! regulation of synaptic plasticity GO:0048167 29 29 0,000 0,01758004 0,02249313 ! proteoglycan metabolic process GO:0006029 30 29 0,000 0,01758004 0,02248508 ! xenobiotic metabolic process GO:0006805 29 29 0,000 0,01758004 0,02247703 ! negative regulation of response to external stimulus GO:0032102 29 29 0,000 0,01758004 0,02246898 ! positive regulation of T cell proliferation GO:0042102 33 29 0,000 0,01758004 0,02246094 ! steroid dehydrogenase activity GO:0016229 29 29 0,000 0,01758004 0,02245291 ! regulation of protein import into nucleus GO:0042306 30 29 0,000 0,01758004 0,02244488 ! clathrin coated vesicle membrane GO:0030665 32 29 0,000 0,01758004 0,02243686 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 30 29 0,000 0,01758004 0,02242884 ! cytosolic small ribosomal subunit GO:0022627 29 29 0,000 0,01758004 0,02242083 ! detection of visible light GO:0009584 29 29 0,000 0,01758004 0,02241283 ! tumor necrosis factor receptor superfamily binding GO:0032813 29 29 0,000 0,01758004 0,02240483 ! acetylglucosaminyltransferase activity GO:0008375 30 29 0,000 0,01758004 0,02239684 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,01758004 0,02238885 ! gene silencing GO:0016458 29 29 0,000 0,01758004 0,02238087 ! hormone binding GO:0042562 30 30 0,000 0,01818132 0,02313809 ! negative regulation of DNA metabolic process GO:0051053 34 30 0,000 0,01818132 0,02312985 ! inner ear morphogenesis GO:0042472 31 30 0,000 0,01818132 0,02312161 ! GPI anchor biosynthetic process GO:0006506 32 30 0,000 0,01818132 0,02311338 ! acrosomal vesicle GO:0001669 32 30 0,000 0,01818132 0,02310516 ! negative regulation of DNA binding GO:0043392 31 30 0,000 0,01818132 0,02309694 ! triglyceride metabolic process GO:0006641 31 30 0,000 0,01818132 0,02308872 ! glutamate receptor activity GO:0008066 33 30 0,000 0,01818132 0,02308052 ! ceramide metabolic process GO:0006672 30 30 0,000 0,01818132 0,02307231 ! cell fate specification GO:0001708 31 30 0,000 0,01818132 0,02306412 ! hexose biosynthetic process GO:0019319 32 30 0,000 0,01818132 0,02305593 ! PDZ domain binding GO:0030165 32 30 0,000 0,01818132 0,02304774 ! AP-type membrane coat adaptor complex GO:0030119 31 30 0,000 0,01818132 0,02303956 GO:0030131|clathrin adaptor complex, ! embryonic epithelial tube formation GO:0001838 32 30 0,000 0,01818132 0,02303139 ! negative regulation of protein transport GO:0051224 30 30 0,000 0,01818132 0,02302322 ! negative regulation of protein complex assembly GO:0031333 30 30 0,000 0,01818132 0,02301506 ! regulation of JAK-STAT cascade GO:0046425 32 30 0,000 0,01818132 0,02300691 ! drug binding GO:0008144 30 30 0,000 0,01818132 0,02299876 ! multicellular organismal macromolecule metabolic process GO:0044259 30 30 0,000 0,01818132 0,02299061 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 33 30 0,000 0,01818132 0,02298248 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,01818132 0,02297434 ! regulation of systemic arterial blood pressure GO:0003073 32 30 0,000 0,01818132 0,02296622 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 31 30 0,000 0,01818132 0,02295809 ! aminopeptidase activity GO:0004177 32 30 0,000 0,01818132 0,02294998 ! detection of light stimulus GO:0009583 30 30 0,000 0,01818132 0,02294187 ! L-amino acid transmembrane transporter activity GO:0015179 30 30 0,000 0,01818132 0,02293377 ! regulation of microtubule-based process GO:0032886 32 30 0,000 0,01818132 0,02292567 ! cysteine-type endopeptidase inhibitor activity GO:0004869 32 30 0,000 0,01818132 0,02291758 ! meiosis I GO:0007127 31 31 0,000 0,01878227 0,02366672 ! negative regulation of cell adhesion GO:0007162 33 31 0,000 0,01878227 0,02365837 ! striated muscle cell differentiation GO:0051146 31 31 0,000 0,01878227 0,02365003 ! GPI anchor metabolic process GO:0006505 33 31 0,000 0,01878227 0,02364169 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,01878227 0,02363336 ! spliceosome assembly GO:0000245 32 31 0,000 0,01878227 0,02362504 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 32 31 0,000 0,01878227 0,02361672 GO:0004601|peroxidase activity, ! unsaturated fatty acid biosynthetic process GO:0006636 32 31 0,000 0,01878227 0,02360841 ! NAD or NADH binding GO:0051287 31 31 0,000 0,01878227 0,0236001 ! positive regulation of neurogenesis GO:0050769 32 31 0,000 0,01878227 0,0235918 ! cyclic nucleotide metabolic process GO:0009187 31 31 0,000 0,01878227 0,0235835 ! nucleotide catabolic process GO:0009166 32 31 0,000 0,01878227 0,02357521 ! condensed nuclear chromosome GO:0000794 32 31 0,000 0,01878227 0,02356693 ! protein methyltransferase activity GO:0008276 36 31 0,000 0,01878227 0,02355865 ! acute-phase response GO:0006953 32 31 0,000 0,01878227 0,02355038 ! peptide transport GO:0015833 32 31 0,000 0,01878227 0,02354211 ! respiratory gaseous exchange GO:0007585 32 31 0,000 0,01878227 0,02353385 ! DNA integrity checkpoint GO:0031570 34 31 0,000 0,01878227 0,0235256 ! Golgi-associated vesicle membrane GO:0030660 34 31 0,000 0,01878227 0,02351735 ! regulation of protein stability GO:0031647 32 31 0,000 0,01878227 0,02350911 ! sarcolemma GO:0042383 33 31 0,000 0,01878227 0,02350087 ! vesicle localization GO:0051648 32 31 0,000 0,01878227 0,02349264 ! microtubule organizing center part GO:0044450 34 31 0,000 0,01878227 0,02348441 ! response to hydrogen peroxide GO:0042542 34 32 0,000 0,01938289 0,02422692 ! DNA helicase activity GO:0003678 34 32 0,000 0,01938289 0,02421844 ! pigment biosynthetic process GO:0046148 34 32 0,000 0,01938289 0,02420997 ! purinergic nucleotide receptor activity GO:0001614 34 32 0,000 0,01938289 0,02420151 GO:0016502|nucleotide receptor activity, ! female gonad development GO:0008585 32 32 0,000 0,01938289 0,02419305 ! late endosome membrane GO:0031902 32 32 0,000 0,01938289 0,02418459 ! positive regulation of cell development GO:0010720 33 32 0,000 0,01938289 0,02417615 ! regulation of Wnt receptor signaling pathway GO:0030111 35 32 0,000 0,01938289 0,02416771 ! hindbrain development GO:0030902 35 32 0,000 0,01938289 0,02415927 ! aerobic respiration GO:0009060 32 32 0,000 0,01938289 0,02415084 ! positive regulation of catabolic process GO:0009896 34 32 0,000 0,01938289 0,02414242 ! regulation of muscle development GO:0048634 33 32 0,000 0,01938289 0,024134 GO:0016202|regulation of striated muscle tissue development, ! cation:sugar symporter activity GO:0005402 32 32 0,000 0,01938289 0,02412559 GO:0005351|sugar:hydrogen symporter activity, ! sphingoid metabolic process GO:0046519 32 32 0,000 0,01938289 0,02411718 ! response to ionizing radiation GO:0010212 33 32 0,000 0,01938289 0,02410878 ! flagellum GO:0019861 32 32 0,000 0,01938289 0,02410039 ! regulation of lymphocyte mediated immunity GO:0002706 36 32 0,000 0,01938289 0,024092 ! I band GO:0031674 35 32 0,000 0,01938289 0,02408361 ! JAK-STAT cascade GO:0007259 34 32 0,000 0,01938289 0,02407524 ! double-stranded RNA binding GO:0003725 33 32 0,000 0,01938289 0,02406687 ! cellular response to insulin stimulus GO:0032869 37 32 0,000 0,01938289 0,0240585 ! adult locomotory behavior GO:0008344 33 32 0,000 0,01938289 0,02405014 ! pyrimidine nucleotide metabolic process GO:0006220 37 32 0,000 0,01938289 0,02404179 ! positive regulation of transcription factor activity GO:0051091 34 33 0,000 0,01998319 0,02477777 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of secretion GO:0051048 34 33 0,000 0,01998319 0,02476917 ! establishment or maintenance of cell polarity GO:0007163 33 33 0,000 0,01998319 0,02476057 ! platelet alpha granule lumen GO:0031093 34 33 0,000 0,01998319 0,02475198 ! negative regulation of binding GO:0051100 34 33 0,000 0,01998319 0,0247434 ! organelle envelope lumen GO:0031970 34 33 0,000 0,01998319 0,02473482 ! protein targeting to membrane GO:0006612 35 33 0,000 0,01998319 0,02472625 ! vesicle coat GO:0030120 36 33 0,000 0,01998319 0,02471769 ! endoribonuclease activity GO:0004521 34 33 0,000 0,01998319 0,02470913 ! monosaccharide biosynthetic process GO:0046364 35 33 0,000 0,01998319 0,02470058 ! glial cell differentiation GO:0010001 33 33 0,000 0,01998319 0,02469203 ! cell junction organization GO:0034330 35 33 0,000 0,01998319 0,02468349 ! tissue remodeling GO:0048771 35 33 0,000 0,01998319 0,02467495 ! segmentation GO:0035282 34 33 0,000 0,01998319 0,02466642 ! steroid hormone receptor binding GO:0035258 33 33 0,000 0,01998319 0,0246579 ! positive regulation of gene-specific transcription GO:0043193 34 33 0,000 0,01998319 0,02464938 ! energy coupled proton transport, down electrochemical gradient GO:0015985 33 33 0,000 0,01998319 0,02464087 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 35 33 0,000 0,01998319 0,02463237 ! hormone biosynthetic process GO:0042446 33 33 0,000 0,01998319 0,02462387 ! androgen receptor signaling pathway GO:0030521 34 33 0,000 0,01998319 0,02461537 ! O-acyltransferase activity GO:0008374 33 33 0,000 0,01998319 0,02460688 ! response to xenobiotic stimulus GO:0009410 33 33 0,000 0,01998319 0,0245984 ! sugar transmembrane transporter activity GO:0051119 34 34 0,000 0,02058316 0,02532821 GO:0015144|carbohydrate transmembrane transporter activity, ! neural tube development GO:0021915 36 34 0,000 0,02058316 0,02531948 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 34 0,000 0,02058316 0,02531076 ! neutral lipid metabolic process GO:0006638 35 34 0,000 0,02058316 0,02530205 GO:0006639|acylglycerol metabolic process, ! lipid homeostasis GO:0055088 34 34 0,000 0,02058316 0,02529334 ! telencephalon development GO:0021537 34 34 0,000 0,02058316 0,02528464 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 35 34 0,000 0,02058316 0,02527595 ! integral to Golgi membrane GO:0030173 34 34 0,000 0,02058316 0,02526726 ! intramolecular oxidoreductase activity GO:0016860 35 34 0,000 0,02058316 0,02525858 ! collagen GO:0005581 35 34 0,000 0,02058316 0,0252499 ! development of primary female sexual characteristics GO:0046545 34 34 0,000 0,02058316 0,02524123 GO:0046660|female sex differentiation, ! DNA-directed RNA polymerase activity GO:0003899 35 34 0,000 0,02058316 0,02523256 GO:0034062|RNA polymerase activity, ! leukocyte chemotaxis GO:0030595 35 34 0,000 0,02058316 0,0252239 GO:0060326|cell chemotaxis, ! sodium channel activity GO:0005272 36 34 0,000 0,02058316 0,02521525 ! carboxypeptidase activity GO:0004180 35 34 0,000 0,02058316 0,0252066 ! spermatid development GO:0007286 34 34 0,000 0,02058316 0,02519796 ! BMP signaling pathway GO:0030509 35 34 0,000 0,02058316 0,02518933 ! specific RNA polymerase II transcription factor activity GO:0003704 35 34 0,000 0,02058316 0,0251807 ! positive regulation of DNA metabolic process GO:0051054 40 35 0,000 0,0211828 0,0259054 ! mitotic cell cycle checkpoint GO:0007093 35 35 0,000 0,0211828 0,02589654 ! regulation of intracellular protein transport GO:0033157 37 35 0,000 0,0211828 0,02588767 ! vesicle lumen GO:0031983 37 35 0,000 0,0211828 0,02587882 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! metanephros development GO:0001656 35 35 0,000 0,0211828 0,02586997 ! regulation of action potential in neuron GO:0019228 38 35 0,000 0,0211828 0,02586112 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 39 35 0,000 0,0211828 0,02585228 ! cytokine production GO:0001816 35 35 0,000 0,0211828 0,02584345 ! carbon-carbon lyase activity GO:0016830 35 35 0,000 0,0211828 0,02583463 ! embryonic pattern specification GO:0009880 36 35 0,000 0,0211828 0,0258258 ! regulation of metal ion transport GO:0010959 38 35 0,000 0,0211828 0,02581699 ! energy reserve metabolic process GO:0006112 36 35 0,000 0,0211828 0,02580818 ! metalloexopeptidase activity GO:0008235 36 35 0,000 0,0211828 0,02579938 ! protein serine/threonine phosphatase complex GO:0008287 38 35 0,000 0,0211828 0,02579058 ! phagocytosis GO:0006909 37 35 0,000 0,0211828 0,02578179 ! regulation of ARF protein signal transduction GO:0032012 40 35 0,000 0,0211828 0,02577301 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 37 35 0,000 0,0211828 0,02576423 ! ion transmembrane transport GO:0034220 35 35 0,000 0,0211828 0,02575546 ! neuropeptide receptor activity GO:0008188 35 35 0,000 0,0211828 0,02574669 ! regulation of leukocyte mediated immunity GO:0002703 39 35 0,000 0,0211828 0,02573793 ! peripheral nervous system development GO:0007422 37 35 0,000 0,0211828 0,02572918 ! female gamete generation GO:0007292 38 35 0,000 0,0211828 0,02572043 ! polyol metabolic process GO:0019751 36 35 0,000 0,0211828 0,02571169 ! negative regulation of adenylate cyclase activity GO:0007194 38 36 0,000 0,02178212 0,02643015 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of hormone secretion GO:0046883 38 36 0,000 0,02178212 0,02642118 ! monocarboxylic acid binding GO:0033293 37 36 0,000 0,02178212 0,0264122 ! polysaccharide biosynthetic process GO:0000271 36 36 0,000 0,02178212 0,02640324 ! regulation of axonogenesis GO:0050770 39 36 0,000 0,02178212 0,02639428 ! glycerol ether metabolic process GO:0006662 37 36 0,000 0,02178212 0,02638533 ! regulation of proteolysis GO:0030162 37 36 0,000 0,02178212 0,02637638 ! integral to endoplasmic reticulum membrane GO:0030176 36 36 0,000 0,02178212 0,02636744 ! regulation of adaptive immune response GO:0002819 40 36 0,000 0,02178212 0,0263585 ! isoprenoid metabolic process GO:0006720 37 36 0,000 0,02178212 0,02634957 ! spermatid differentiation GO:0048515 36 36 0,000 0,02178212 0,02634065 ! phosphoinositide biosynthetic process GO:0046489 38 36 0,000 0,02178212 0,02633173 ! ER to Golgi vesicle-mediated transport GO:0006888 36 36 0,000 0,02178212 0,02632282 ! condensed chromosome kinetochore GO:0000777 37 36 0,000 0,02178212 0,02631392 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 38 36 0,000 0,02178212 0,02630502 ! neuropeptide binding GO:0042923 36 36 0,000 0,02178212 0,02629613 ! organic anion transport GO:0015711 37 36 0,000 0,02178212 0,02628724 ! carbohydrate homeostasis GO:0033500 38 36 0,000 0,02178212 0,02627836 GO:0042593|glucose homeostasis, ! complement activation GO:0006956 39 36 0,000 0,02178212 0,02626948 ! antigen binding GO:0003823 36 36 0,000 0,02178212 0,02626062 ! extrinsic to plasma membrane GO:0019897 36 36 0,000 0,02178212 0,02625175 ! cytokinesis GO:0000910 40 36 0,000 0,02178212 0,0262429 ! coated pit GO:0005905 42 36 0,000 0,02178212 0,02623404 ! positive regulation of leukocyte proliferation GO:0070665 40 36 0,000 0,02178212 0,0262252 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein amino acid N-linked glycosylation GO:0006487 40 37 0,000 0,02238111 0,02693729 ! ribonucleoside metabolic process GO:0009119 43 37 0,000 0,02238111 0,02692821 ! DNA-dependent ATPase activity GO:0008094 39 37 0,000 0,02238111 0,02691914 ! regulation of T cell differentiation GO:0045580 41 37 0,000 0,02238111 0,02691008 ! biopolymer methylation GO:0043414 42 37 0,000 0,02238111 0,02690102 ! intrinsic to Golgi membrane GO:0031228 37 37 0,000 0,02238111 0,02689197 ! protein homooligomerization GO:0051260 38 37 0,000 0,02238111 0,02688293 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 38 37 0,000 0,02238111 0,02687389 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 41 37 0,000 0,02238111 0,02686485 ! multicellular organismal metabolic process GO:0044236 38 37 0,000 0,02238111 0,02685583 ! amino acid binding GO:0016597 40 37 0,000 0,02238111 0,0268468 ! maintenance of protein location GO:0045185 38 37 0,000 0,02238111 0,02683779 ! maintenance of location in cell GO:0051651 38 37 0,000 0,02238111 0,02682878 ! solute:hydrogen symporter activity GO:0015295 37 37 0,000 0,02238111 0,02681978 ! proton-transporting two-sector ATPase complex GO:0016469 37 37 0,000 0,02238111 0,02681078 ! ear morphogenesis GO:0042471 39 38 0,000 0,02297977 0,0275187 ! odontogenesis GO:0042476 40 38 0,000 0,02297977 0,02750948 ! organic ether metabolic process GO:0018904 39 38 0,000 0,02297977 0,02750026 ! alcohol biosynthetic process GO:0046165 40 38 0,000 0,02297977 0,02749104 ! positive regulation of DNA binding GO:0043388 39 38 0,000 0,02297977 0,02748184 ! B cell differentiation GO:0030183 40 38 0,000 0,02297977 0,02747264 ! clathrin coat GO:0030118 43 38 0,000 0,02297977 0,02746344 ! regulation of endocytosis GO:0030100 39 38 0,000 0,02297977 0,02745425 ! dorsal/ventral pattern formation GO:0009953 38 38 0,000 0,02297977 0,02744507 ! cell growth GO:0016049 40 38 0,000 0,02297977 0,0274359 ! positive regulation of defense response GO:0031349 38 38 0,000 0,02297977 0,02742673 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 38 0,000 0,02297977 0,02741756 ! condensed chromosome, centromeric region GO:0000779 39 38 0,000 0,02297977 0,02740841 ! learning GO:0007612 42 38 0,000 0,02297977 0,02739925 ! negative regulation of protein complex disassembly GO:0043242 40 38 0,000 0,02297977 0,02739011 ! monocarboxylic acid transport GO:0015718 39 38 0,000 0,02297977 0,02738097 ! endosome transport GO:0016197 40 38 0,000 0,02297977 0,02737184 ! hormone-mediated signaling GO:0009755 39 38 0,000 0,02297977 0,02736271 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 40 38 0,000 0,02297977 0,02735359 ! N-methyltransferase activity GO:0008170 42 38 0,000 0,02297977 0,02734447 ! cytosolic large ribosomal subunit GO:0022625 38 38 0,000 0,02297977 0,02733537 ! pigment metabolic process GO:0042440 42 38 0,000 0,02297977 0,02732626 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 38 38 0,000 0,02297977 0,02731717 ! RNA modification GO:0009451 39 38 0,000 0,02297977 0,02730808 ! regulation of nucleocytoplasmic transport GO:0046822 41 39 0,000 0,02357811 0,02800979 ! Notch signaling pathway GO:0007219 41 39 0,000 0,02357811 0,02800048 ! keratin filament GO:0045095 41 39 0,000 0,02357811 0,02799117 ! peroxisomal membrane GO:0005778 40 39 0,000 0,02357811 0,02798187 GO:0031903|microbody membrane, ! mitochondrial respiratory chain complex I GO:0005747 39 39 0,000 0,02357811 0,02797257 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! actin filament binding GO:0051015 39 39 0,000 0,02357811 0,02796328 ! regulation of protein secretion GO:0050708 41 39 0,000 0,02357811 0,027954 ! cis-trans isomerase activity GO:0016859 39 39 0,000 0,02357811 0,02794472 ! regulation of cell morphogenesis involved in differentiation GO:0010769 42 39 0,000 0,02357811 0,02793545 ! viral infectious cycle GO:0019058 39 39 0,000 0,02357811 0,02792618 ! mammary gland development GO:0030879 41 39 0,000 0,02357811 0,02791692 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 39 0,000 0,02357811 0,02790767 ! amine receptor activity GO:0008227 41 39 0,000 0,02357811 0,02789842 ! positive regulation of response to external stimulus GO:0032103 39 39 0,000 0,02357811 0,02788918 ! monosaccharide binding GO:0048029 39 39 0,000 0,02357811 0,02787995 ! NADH dehydrogenase (ubiquinone) activity GO:0008137 39 39 0,000 0,02357811 0,02787072 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! phosphotransferase activity, phosphate group as acceptor GO:0016776 44 40 0,000 0,02417612 0,02856815 ! response to estrogen stimulus GO:0043627 41 40 0,000 0,02417612 0,0285587 ! peptide metabolic process GO:0006518 41 40 0,000 0,02417612 0,02854925 ! regulation of Rab protein signal transduction GO:0032483 41 40 0,000 0,02417612 0,02853981 GO:0032313|regulation of Rab GTPase activity, ! T cell differentiation GO:0030217 45 40 0,000 0,02417612 0,02853038 ! regulation of multicellular organism growth GO:0040014 42 40 0,000 0,02417612 0,02852096 ! regulation of gene expression, epigenetic GO:0040029 43 40 0,000 0,02417612 0,02851154 ! neuron migration GO:0001764 42 40 0,000 0,02417612 0,02850213 ! inositol or phosphatidylinositol kinase activity GO:0004428 42 40 0,000 0,02417612 0,02849272 ! structural constituent of muscle GO:0008307 43 40 0,000 0,02417612 0,02848332 ! gliogenesis GO:0042063 40 40 0,000 0,02417612 0,02847392 ! feeding behavior GO:0007631 40 40 0,000 0,02417612 0,02846454 ! protein serine/threonine phosphatase activity GO:0004722 42 40 0,000 0,02417612 0,02845515 ! positive regulation of cytokine biosynthetic process GO:0042108 41 40 0,000 0,02417612 0,02844578 ! sulfur compound biosynthetic process GO:0044272 41 40 0,000 0,02417612 0,02843641 ! inorganic anion transmembrane transporter activity GO:0015103 42 40 0,000 0,02417612 0,02842705 ! chromatin remodeling GO:0006338 43 40 0,000 0,02417612 0,02841769 ! response to insulin stimulus GO:0032868 45 40 0,000 0,02417612 0,02840834 ! activation of adenylate cyclase activity GO:0007190 42 41 0,000 0,02477381 0,02910108 ! positive regulation of binding GO:0051099 42 41 0,000 0,02477381 0,02909151 ! response to reactive oxygen species GO:0000302 43 41 0,000 0,02477381 0,02908195 ! solute:sodium symporter activity GO:0015370 41 41 0,000 0,02477381 0,02907239 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 44 41 0,000 0,02477381 0,02906284 GO:0046328|regulation of JNK cascade, ! mesenchymal cell development GO:0014031 43 41 0,000 0,02477381 0,02905329 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! heterocycle biosynthetic process GO:0018130 43 41 0,000 0,02477381 0,02904376 ! exonuclease activity GO:0004527 42 41 0,000 0,02477381 0,02903422 ! regulation of myeloid cell differentiation GO:0045637 43 41 0,000 0,02477381 0,0290247 ! hydro-lyase activity GO:0016836 44 41 0,000 0,02477381 0,02901518 ! positive regulation of protein transport GO:0051222 44 41 0,000 0,02477381 0,02900566 ! receptor-mediated endocytosis GO:0006898 43 41 0,000 0,02477381 0,02899616 ! regulation of neuron projection development GO:0010975 44 41 0,000 0,02477381 0,02898666 ! metal cluster binding GO:0051540 43 41 0,000 0,02477381 0,02897716 GO:0051536|iron-sulfur cluster binding, ! embryonic skeletal system morphogenesis GO:0048704 42 41 0,000 0,02477381 0,02896767 ! development of primary male sexual characteristics GO:0046546 41 41 0,000 0,02477381 0,02895819 ! double-strand break repair GO:0006302 41 41 0,000 0,02477381 0,02894872 ! Rab GTPase activator activity GO:0005097 42 41 0,000 0,02477381 0,02893925 ! RNA catabolic process GO:0006401 44 42 0,000 0,02537117 0,02962736 ! organellar ribosome GO:0000313 43 42 0,000 0,02537117 0,02961767 GO:0005761|mitochondrial ribosome, ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 44 42 0,000 0,02537117 0,02960799 ! damaged DNA binding GO:0003684 42 42 0,000 0,02537117 0,02959832 ! MHC protein complex GO:0042611 42 42 0,000 0,02537117 0,02958865 ! regulation of epithelial cell proliferation GO:0050678 44 42 0,000 0,02537117 0,02957899 ! negative regulation of cell migration GO:0030336 44 42 0,000 0,02537117 0,02956934 ! icosanoid metabolic process GO:0006690 43 42 0,000 0,02537117 0,02955969 ! chemokine activity GO:0008009 42 42 0,000 0,02537117 0,02955005 ! ruffle GO:0001726 44 42 0,000 0,02537117 0,02954042 ! pigmentation GO:0043473 46 42 0,000 0,02537117 0,02953079 ! developmental growth GO:0048589 42 42 0,000 0,02537117 0,02952117 ! methylation GO:0032259 47 42 0,000 0,02537117 0,02951155 ! glycolysis GO:0006096 42 42 0,000 0,02537117 0,02950194 ! morphogenesis of embryonic epithelium GO:0016331 44 42 0,000 0,02537117 0,02949234 ! regulation of tube size GO:0035150 44 42 0,000 0,02537117 0,02948274 GO:0050880|regulation of blood vessel size, ! branching morphogenesis of a tube GO:0048754 43 42 0,000 0,02537117 0,02947315 ! general RNA polymerase II transcription factor activity GO:0016251 44 42 0,000 0,02537117 0,02946356 ! cellular amino acid derivative biosynthetic process GO:0042398 43 42 0,000 0,02537117 0,02945398 ! positive regulation of adenylate cyclase activity GO:0045762 44 43 0,000 0,02596821 0,0301373 ! transferase activity, transferring pentosyl groups GO:0016763 45 43 0,000 0,02596821 0,03012751 ! epithelial cell differentiation GO:0030855 45 43 0,000 0,02596821 0,03011772 ! detection of stimulus involved in sensory perception GO:0050906 43 43 0,000 0,02596821 0,03010795 ! sulfotransferase activity GO:0008146 44 43 0,000 0,02596821 0,03009817 ! cellular polysaccharide metabolic process GO:0044264 44 43 0,000 0,02596821 0,03008841 ! channel regulator activity GO:0016247 46 43 0,000 0,02596821 0,03007865 ! histone modification GO:0016570 44 43 0,000 0,02596821 0,0300689 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 45 43 0,000 0,02596821 0,03005915 ! synaptosome GO:0019717 47 43 0,000 0,02596821 0,03004941 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 45 44 0,000 0,02656492 0,03072994 ! platelet alpha granule GO:0031091 46 44 0,000 0,02656492 0,03071999 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 44 44 0,000 0,02656492 0,03071005 ! regulation of ossification GO:0030278 48 44 0,000 0,02656492 0,03070011 ! cell recognition GO:0008037 46 44 0,000 0,02656492 0,03069017 ! positive regulation of cyclase activity GO:0031281 45 44 0,000 0,02656492 0,03068025 ! regulation of lymphocyte differentiation GO:0045619 48 44 0,000 0,02656492 0,03067033 ! regulation of actin filament polymerization GO:0030833 45 44 0,000 0,02656492 0,03066042 ! regulation of protein complex disassembly GO:0043244 46 44 0,000 0,02656492 0,03065051 ! regulation of ion transport GO:0043269 47 44 0,000 0,02656492 0,03064061 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 50 44 0,000 0,02656492 0,03063072 ! inner ear development GO:0048839 46 44 0,000 0,02656492 0,03062083 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 48 44 0,000 0,02656492 0,03061095 ! amino acid transmembrane transporter activity GO:0015171 44 44 0,000 0,02656492 0,03060107 ! chemokine receptor binding GO:0042379 44 44 0,000 0,02656492 0,03059121 ! regulation of action potential GO:0001508 50 45 0,000 0,02716131 0,0312679 ! regulation of gene-specific transcription GO:0032583 47 45 0,000 0,02716131 0,03125782 ! cellular amino acid biosynthetic process GO:0008652 47 45 0,000 0,02716131 0,03124775 ! response to temperature stimulus GO:0009266 45 45 0,000 0,02716131 0,03123769 ! nucleoside monophosphate biosynthetic process GO:0009124 50 45 0,000 0,02716131 0,03122763 ! positive regulation of lyase activity GO:0051349 46 45 0,000 0,02716131 0,03121758 ! regulation of neuron apoptosis GO:0043523 45 45 0,000 0,02716131 0,03120754 ! excretion GO:0007588 46 45 0,000 0,02716131 0,0311975 ! protein phosphatase regulator activity GO:0019888 49 45 0,000 0,02716131 0,03118747 ! JNK cascade GO:0007254 45 45 0,000 0,02716131 0,03117744 ! SH3/SH2 adaptor activity GO:0005070 48 45 0,000 0,02716131 0,03116742 ! regulation of cell shape GO:0008360 46 45 0,000 0,02716131 0,03115741 ! epithelial tube morphogenesis GO:0060562 47 45 0,000 0,02716131 0,03114741 ! microbody part GO:0044438 46 45 0,000 0,02716131 0,03113741 GO:0044439|peroxisomal part, ! auxiliary transport protein activity GO:0015457 50 46 0,000 0,02775737 0,03181051 ! ATP synthesis coupled electron transport GO:0042773 46 46 0,000 0,02775737 0,03180031 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! microtubule binding GO:0008017 49 46 0,000 0,02775737 0,03179011 ! regulation of inflammatory response GO:0050727 46 46 0,000 0,02775737 0,03177992 ! transport vesicle GO:0030133 49 46 0,000 0,02775737 0,03176973 ! glutamine family amino acid metabolic process GO:0009064 49 46 0,000 0,02775737 0,03175955 ! synapse organization GO:0050808 51 46 0,000 0,02775737 0,03174938 ! nuclear matrix GO:0016363 49 46 0,000 0,02775737 0,03173921 ! striated muscle contraction GO:0006941 49 46 0,000 0,02775737 0,03172905 ! unsaturated fatty acid metabolic process GO:0033559 47 46 0,000 0,02775737 0,0317189 ! antioxidant activity GO:0016209 47 46 0,000 0,02775737 0,03170875 ! activation of caspase activity GO:0006919 49 46 0,000 0,02775737 0,03169861 ! aging GO:0007568 48 46 0,000 0,02775737 0,03168848 ! male sex differentiation GO:0046661 46 46 0,000 0,02775737 0,03167835 ! coated vesicle membrane GO:0030662 49 46 0,000 0,02775737 0,03166823 ! covalent chromatin modification GO:0016569 47 46 0,000 0,02775737 0,03165812 ! RNA elongation from RNA polymerase II promoter GO:0006368 48 46 0,000 0,02775737 0,03164801 ! protein amino acid lipidation GO:0006497 50 47 0,000 0,02835311 0,03231693 ! stress-activated protein kinase signaling pathway GO:0031098 47 47 0,000 0,02835311 0,03230662 ! carbohydrate transport GO:0008643 47 47 0,000 0,02835311 0,03229631 ! proteasome complex GO:0000502 48 47 0,000 0,02835311 0,03228601 ! immunoglobulin mediated immune response GO:0016064 50 47 0,000 0,02835311 0,03227572 ! phosphatase regulator activity GO:0019208 51 47 0,000 0,02835311 0,03226544 ! vesicle organization GO:0016050 50 47 0,000 0,02835311 0,03225516 ! vascular process in circulatory system GO:0003018 49 47 0,000 0,02835311 0,03224488 ! cell cortex part GO:0044448 51 47 0,000 0,02835311 0,03223462 ! lipid modification GO:0030258 49 48 0,000 0,02894852 0,03290107 ! cytokine-mediated signaling pathway GO:0019221 49 48 0,000 0,02894852 0,0328906 ! morphogenesis of a branching structure GO:0001763 49 48 0,000 0,02894852 0,03288014 ! mitochondrial transport GO:0006839 49 48 0,000 0,02894852 0,03286968 ! viral reproductive process GO:0022415 52 48 0,000 0,02894852 0,03285924 ! leukocyte migration GO:0050900 49 48 0,000 0,02894852 0,03284879 ! neuromuscular process GO:0050905 49 48 0,000 0,02894852 0,03283836 ! gastrulation GO:0007369 50 48 0,000 0,02894852 0,03282793 ! detection of abiotic stimulus GO:0009582 48 48 0,000 0,02894852 0,03281751 ! heterocycle catabolic process GO:0046700 53 48 0,000 0,02894852 0,03280709 ! B cell mediated immunity GO:0019724 51 48 0,000 0,02894852 0,03279669 ! protein N-terminus binding GO:0047485 51 48 0,000 0,02894852 0,03278628 ! transferase activity, transferring sulfur-containing groups GO:0016782 50 49 0,000 0,02954361 0,03344966 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 54 49 0,000 0,02954361 0,03343905 ! intrinsic to endoplasmic reticulum membrane GO:0031227 50 49 0,000 0,02954361 0,03342846 ! ribonuclease activity GO:0004540 50 49 0,000 0,02954361 0,03341787 ! positive regulation of organelle organization GO:0010638 49 49 0,000 0,02954361 0,03340729 ! lamellipodium GO:0030027 53 49 0,000 0,02954361 0,03339671 ! negative regulation of cell motion GO:0051271 51 49 0,000 0,02954361 0,03338614 ! nucleosome GO:0000786 49 49 0,000 0,02954361 0,03337558 ! kinetochore GO:0000776 50 49 0,000 0,02954361 0,03336503 ! membrane fusion GO:0006944 51 49 0,000 0,02954361 0,03335448 ! endocrine system development GO:0035270 49 49 0,000 0,02954361 0,03334394 ! RNA elongation GO:0006354 51 49 0,000 0,02954361 0,0333334 ! glycosaminoglycan metabolic process GO:0030203 53 50 0,000 0,03013837 0,03399372 ! regulation of actin polymerization or depolymerization GO:0008064 51 50 0,000 0,03013837 0,03398299 ! basement membrane GO:0005604 51 50 0,000 0,03013837 0,03397226 ! regulation of intracellular transport GO:0032386 52 50 0,000 0,03013837 0,03396154 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,03013837 0,03395083 ! maintenance of location GO:0051235 51 50 0,000 0,03013837 0,03394012 ! cell redox homeostasis GO:0045454 51 50 0,000 0,03013837 0,03392942 ! integrin binding GO:0005178 53 50 0,000 0,03013837 0,03391873 ! amino acid activation GO:0043038 50 50 0,000 0,03013837 0,03390804 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! establishment of organelle localization GO:0051656 53 50 0,000 0,03013837 0,03389736 ! regulation of bone remodeling GO:0046850 55 51 0,000 0,03073281 0,03455506 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 52 51 0,000 0,03073281 0,03454418 ! late endosome GO:0005770 51 51 0,000 0,03073281 0,03453331 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 56 51 0,000 0,03073281 0,03452245 ! ligase activity, forming carbon-oxygen bonds GO:0016875 51 51 0,000 0,03073281 0,03451159 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! negative regulation of response to stimulus GO:0048585 55 51 0,000 0,03073281 0,03450074 ! carbon-oxygen lyase activity GO:0016835 54 51 0,000 0,03073281 0,0344899 ! skeletal muscle fiber development GO:0048741 54 51 0,000 0,03073281 0,03447906 ! lipoprotein biosynthetic process GO:0042158 54 51 0,000 0,03073281 0,03446824 ! heart morphogenesis GO:0003007 54 51 0,000 0,03073281 0,03445741 ! steroid hormone receptor activity GO:0003707 53 51 0,000 0,03073281 0,0344466 ! antiporter activity GO:0015297 52 51 0,000 0,03073281 0,03443579 ! respiratory electron transport chain GO:0022904 52 52 0,000 0,03132693 0,03509048 ! positive regulation of cell migration GO:0030335 55 52 0,000 0,03132693 0,03507948 ! Golgi-associated vesicle GO:0005798 55 52 0,000 0,03132693 0,03506848 ! sphingolipid metabolic process GO:0006665 53 52 0,000 0,03132693 0,03505749 ! cell maturation GO:0048469 55 52 0,000 0,03132693 0,03504651 ! regulation of protein polymerization GO:0032271 53 52 0,000 0,03132693 0,03503553 ! regulation of actin filament length GO:0030832 53 52 0,000 0,03132693 0,03502456 ! regulation of cell projection organization GO:0031344 55 52 0,000 0,03132693 0,0350136 ! chloride transport GO:0006821 53 52 0,000 0,03132693 0,03500264 ! positive regulation of caspase activity GO:0043280 55 52 0,000 0,03132693 0,0349917 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 55 52 0,000 0,03132693 0,03498075 ! regulation of muscle contraction GO:0006937 56 52 0,000 0,03132693 0,03496982 ! negative regulation of cytoskeleton organization GO:0051494 57 52 0,000 0,03132693 0,03495889 ! glucose catabolic process GO:0006007 52 52 0,000 0,03132693 0,03494797 ! generation of a signal involved in cell-cell signaling GO:0003001 54 52 0,000 0,03132693 0,03493705 ! small ribosomal subunit GO:0015935 52 52 0,000 0,03132693 0,03492615 ! cytokine receptor activity GO:0004896 53 52 0,000 0,03132693 0,03491525 ! activation of phospholipase C activity GO:0007202 55 53 0,000 0,03192072 0,03556595 GO:0010863|positive regulation of phospholipase C activity, ! nucleoside monophosphate metabolic process GO:0009123 58 53 0,000 0,03192072 0,03555486 ! nucleoside metabolic process GO:0009116 61 53 0,000 0,03192072 0,03554377 ! N-acetyltransferase activity GO:0008080 54 53 0,000 0,03192072 0,03553269 ! synaptic vesicle GO:0008021 57 53 0,000 0,03192072 0,03552162 ! viral reproduction GO:0016032 57 53 0,000 0,03192072 0,03551056 ! cell projection assembly GO:0030031 56 53 0,000 0,03192072 0,0354995 ! mRNA binding GO:0003729 55 53 0,000 0,03192072 0,03548844 ! single fertilization GO:0007338 55 53 0,000 0,03192072 0,0354774 ! axon GO:0030424 58 54 0,000 0,03251419 0,03612575 ! heat shock protein binding GO:0031072 54 54 0,000 0,03251419 0,03611451 ! regulation of neurotransmitter levels GO:0001505 60 54 0,000 0,03251419 0,03610328 ! positive regulation of phospholipase activity GO:0010518 56 54 0,000 0,03251419 0,03609206 ! tRNA processing GO:0008033 55 54 0,000 0,03251419 0,03608084 ! regulation of cellular response to stress GO:0080135 57 54 0,000 0,03251419 0,03606964 ! growth factor receptor binding GO:0070851 56 54 0,000 0,03251419 0,03605843 ! regulation of protein catabolic process GO:0042176 57 54 0,000 0,03251419 0,03604724 ! regulation of tissue remodeling GO:0034103 58 54 0,000 0,03251419 0,03603605 ! regulation of cellular component size GO:0032535 56 55 0,000 0,03310733 0,03668206 ! response to peptide hormone stimulus GO:0043434 60 55 0,000 0,03310733 0,03667068 ! glycerophospholipid biosynthetic process GO:0046474 59 55 0,000 0,03310733 0,03665931 ! large ribosomal subunit GO:0015934 56 55 0,000 0,03310733 0,03664795 ! protein amino acid autophosphorylation GO:0046777 57 55 0,000 0,03310733 0,03663659 ! positive regulation of secretion GO:0051047 60 56 0,000 0,03370015 0,03728106 ! regulation of mitosis GO:0007088 56 56 0,000 0,03370015 0,03726951 GO:0051783|regulation of nuclear division, ! actin filament organization GO:0007015 59 56 0,000 0,03370015 0,03725797 ! regulation of phospholipase activity GO:0010517 58 56 0,000 0,03370015 0,03724644 ! coenzyme biosynthetic process GO:0009108 59 56 0,000 0,03370015 0,03723492 ! cellular amino acid catabolic process GO:0009063 59 56 0,000 0,03370015 0,0372234 ! cartilage development GO:0051216 59 56 0,000 0,03370015 0,03721189 ! regulation of protein complex assembly GO:0043254 57 56 0,000 0,03370015 0,03720039 ! receptor signaling protein serine/threonine kinase activity GO:0004702 58 56 0,000 0,03370015 0,03718889 ! mesoderm development GO:0007498 57 56 0,000 0,03370015 0,0371774 ! regulation of transcription factor activity GO:0051090 59 57 0,000 0,03429265 0,03781935 GO:0090046|regulation of transcription regulator activity, ! ear development GO:0043583 60 57 0,000 0,03429265 0,03780768 ! chromosome segregation GO:0007059 59 57 0,000 0,03429265 0,03779601 ! positive regulation of T cell activation GO:0050870 62 57 0,000 0,03429265 0,03778434 ! kidney development GO:0001822 60 57 0,000 0,03429265 0,03777269 ! positive regulation of lipase activity GO:0060193 59 57 0,000 0,03429265 0,03776104 ! integrin-mediated signaling pathway GO:0007229 61 57 0,000 0,03429265 0,0377494 ! adult behavior GO:0030534 60 57 0,000 0,03429265 0,03773777 ! steroid hormone receptor signaling pathway GO:0030518 58 57 0,000 0,03429265 0,03772614 ! myosin complex GO:0016459 59 57 0,000 0,03429265 0,03771452 ! regulation of angiogenesis GO:0045765 60 58 0,000 0,03488483 0,03835398 ! lysosomal membrane GO:0005765 59 58 0,000 0,03488483 0,03834217 ! extracellular matrix organization GO:0030198 59 58 0,000 0,03488483 0,03833038 ! positive regulation of cell motion GO:0051272 61 58 0,000 0,03488483 0,03831859 ! regulation of vesicle-mediated transport GO:0060627 60 58 0,000 0,03488483 0,0383068 ! detection of external stimulus GO:0009581 59 58 0,000 0,03488483 0,03829503 ! dendrite GO:0030425 61 59 0,000 0,03547668 0,03893277 ! molecular adaptor activity GO:0060090 65 59 0,000 0,03547668 0,03892081 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 60 59 0,000 0,03547668 0,03890885 GO:0051213|dioxygenase activity, ! embryonic limb morphogenesis GO:0030326 63 59 0,000 0,03547668 0,03889691 GO:0035113|embryonic appendage morphogenesis, ! ubiquitin thiolesterase activity GO:0004221 62 59 0,000 0,03547668 0,03888497 ! regulation of heart contraction GO:0008016 62 59 0,000 0,03547668 0,03887304 ! copper ion binding GO:0005507 61 59 0,000 0,03547668 0,03886111 ! activation of immune response GO:0002253 68 59 0,000 0,03547668 0,0388492 ! aminoglycan metabolic process GO:0006022 62 59 0,000 0,03547668 0,03883729 ! amine transmembrane transporter activity GO:0005275 59 59 0,000 0,03547668 0,03882538 ! chromatin remodeling complex GO:0016585 61 59 0,000 0,03547668 0,03881349 ! cell soma GO:0043025 63 59 0,000 0,03547668 0,0388016 ! regulation of homeostatic process GO:0032844 68 59 0,000 0,03547668 0,03878972 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 61 60 0,000 0,03606821 0,03942442 ! occluding junction GO:0070160 60 60 0,000 0,03606821 0,03941236 GO:0005923|tight junction, ! regulation of lipid metabolic process GO:0019216 63 60 0,000 0,03606821 0,0394003 ! regulation of cytokine biosynthetic process GO:0042035 63 60 0,000 0,03606821 0,03938825 ! lymphocyte mediated immunity GO:0002449 63 60 0,000 0,03606821 0,03937621 ! chloride channel activity GO:0005254 61 60 0,000 0,03606821 0,03936418 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 62 61 0,000 0,03665942 0,03999719 ! cell cycle checkpoint GO:0000075 64 61 0,000 0,03665942 0,03998497 ! fertilization GO:0009566 64 61 0,000 0,03665942 0,03997276 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 65 61 0,000 0,03665942 0,03996056 ! gonad development GO:0008406 61 61 0,000 0,03665942 0,03994836 ! protein maturation by peptide bond cleavage GO:0051605 64 61 0,000 0,03665942 0,03993618 ! regulation of immune effector process GO:0002697 65 61 0,000 0,03665942 0,039924 ! amine catabolic process GO:0009310 68 62 0,000 0,03725031 0,04055513 ! phosphoinositide metabolic process GO:0030384 66 62 0,000 0,03725031 0,04054277 ! glycerolipid biosynthetic process GO:0045017 66 62 0,000 0,03725031 0,04053042 ! coated membrane GO:0048475 67 62 0,000 0,03725031 0,04051808 GO:0030117|membrane coat, ! hexose catabolic process GO:0019320 63 62 0,000 0,03725031 0,04050574 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 63 62 0,000 0,03725031 0,04049341 ! extracellular ligand-gated ion channel activity GO:0005230 67 62 0,000 0,03725031 0,04048108 ! germ cell development GO:0007281 62 62 0,000 0,03725031 0,04046877 ! ligand-dependent nuclear receptor activity GO:0004879 65 62 0,000 0,03725031 0,04045646 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 70 63 0,000 0,03784087 0,04108536 ! mitochondrial respiratory chain GO:0005746 65 63 0,000 0,03784087 0,04107287 ! negative regulation of ligase activity GO:0051352 64 63 0,000 0,03784087 0,04106039 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein oligomerization GO:0051259 64 63 0,000 0,03784087 0,04104792 ! transition metal ion transport GO:0000041 65 63 0,000 0,03784087 0,04103545 ! appendage morphogenesis GO:0035107 67 63 0,000 0,03784087 0,04102299 GO:0035108|limb morphogenesis, ! activation of MAPK activity GO:0000187 69 63 0,000 0,03784087 0,04101054 ! cellular defense response GO:0006968 64 63 0,000 0,03784087 0,0409981 ! B cell activation GO:0042113 66 63 0,000 0,03784087 0,04098567 ! antigen processing and presentation GO:0019882 64 63 0,000 0,03784087 0,04097324 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 65 63 0,000 0,03784087 0,04096082 ! microtubule motor activity GO:0003777 67 63 0,000 0,03784087 0,04094841 ! intracellular receptor-mediated signaling pathway GO:0030522 64 63 0,000 0,03784087 0,040936 ! organelle localization GO:0051640 66 63 0,000 0,03784087 0,0409236 ! transforming growth factor beta receptor signaling pathway GO:0007179 67 64 0,000 0,03843111 0,04154935 ! respiratory chain GO:0070469 66 64 0,000 0,03843111 0,04153677 ! developmental maturation GO:0021700 67 64 0,000 0,03843111 0,0415242 ! amino acid transport GO:0006865 64 64 0,000 0,03843111 0,04151164 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 66 64 0,000 0,03843111 0,04149909 ! anion channel activity GO:0005253 65 64 0,000 0,03843111 0,04148655 ! cellular hormone metabolic process GO:0034754 65 65 0,000 0,03902103 0,04211064 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 65 0,000 0,03902103 0,04209791 ! negative regulation of cell growth GO:0030308 68 65 0,000 0,03902103 0,0420852 ! nuclear pore GO:0005643 69 65 0,000 0,03902103 0,04207249 ! regulation of MAPKKK cascade GO:0043408 72 65 0,000 0,03902103 0,04205979 ! rhythmic process GO:0048511 66 65 0,000 0,03902103 0,0420471 ! regulation of lipase activity GO:0060191 67 65 0,000 0,03902103 0,04203442 ! adaptive immune response GO:0002250 68 65 0,000 0,03902103 0,04202174 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! appendage development GO:0048736 69 65 0,000 0,03902103 0,04200907 GO:0060173|limb development, ! skeletal system morphogenesis GO:0048705 66 65 0,000 0,03902103 0,04199641 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 67 65 0,000 0,03902103 0,04198376 ! lipoprotein metabolic process GO:0042157 68 65 0,000 0,03902103 0,04197111 ! DNA-dependent DNA replication GO:0006261 66 65 0,000 0,03902103 0,04195848 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 71 66 0,000 0,03961063 0,04257964 ! endoplasmic reticulum lumen GO:0005788 66 66 0,000 0,03961063 0,04256682 ! urogenital system development GO:0001655 69 66 0,000 0,03961063 0,04255402 ! response to steroid hormone stimulus GO:0048545 69 66 0,000 0,03961063 0,04254122 ! diacylglycerol binding GO:0019992 71 66 0,000 0,03961063 0,04252843 ! amine binding GO:0043176 70 66 0,000 0,03961063 0,04251565 ! response to nutrient GO:0007584 67 66 0,000 0,03961063 0,04250287 ! acetyltransferase activity GO:0016407 68 66 0,000 0,03961063 0,0424901 ! negative regulation of cell size GO:0045792 70 67 0,000 0,0401999 0,04310927 ! intracellular protein transmembrane transport GO:0065002 70 67 0,000 0,0401999 0,04309632 ! tubulin binding GO:0015631 70 67 0,000 0,0401999 0,04308339 ! positive regulation of lymphocyte activation GO:0051251 72 67 0,000 0,0401999 0,04307046 ! activation of protein kinase activity GO:0032147 70 67 0,000 0,0401999 0,04305755 ! humoral immune response GO:0006959 70 67 0,000 0,0401999 0,04304463 ! nuclear hormone receptor binding GO:0035257 68 67 0,000 0,0401999 0,04303173 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 69 67 0,000 0,0401999 0,04301884 ! ubiquitin ligase complex GO:0000151 71 67 0,000 0,0401999 0,04300595 ! nucleosome assembly GO:0006334 69 67 0,000 0,0401999 0,04299307 ! transcription initiation from RNA polymerase II promoter GO:0006367 71 67 0,000 0,0401999 0,0429802 ! muscle cell differentiation GO:0042692 68 68 0,000 0,04078886 0,04359683 ! fatty acid biosynthetic process GO:0006633 70 68 0,000 0,04078886 0,04358379 ! protein import into nucleus GO:0006606 72 68 0,000 0,04078886 0,04357075 ! lymphocyte differentiation GO:0030098 75 68 0,000 0,04078886 0,04355772 ! regulation of actin cytoskeleton organization GO:0032956 74 68 0,000 0,04078886 0,0435447 ! protein-DNA complex GO:0032993 69 68 0,000 0,04078886 0,04353168 ! learning or memory GO:0007611 72 68 0,000 0,04078886 0,04351868 ! chloride ion binding GO:0031404 70 68 0,000 0,04078886 0,04350568 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 71 68 0,000 0,04078886 0,04349269 ! chromatin assembly GO:0031497 70 68 0,000 0,04078886 0,04347971 ! leukocyte mediated immunity GO:0002443 71 68 0,000 0,04078886 0,04346673 ! extrinsic to membrane GO:0019898 68 68 0,000 0,04078886 0,04345376 ! calcium channel activity GO:0005262 73 68 0,000 0,04078886 0,0434408 ! ribonucleoprotein complex assembly GO:0022618 69 68 0,000 0,04078886 0,04342785 ! N-acyltransferase activity GO:0016410 69 68 0,000 0,04078886 0,04341491 ! positive regulation of ligase activity GO:0051351 71 69 0,000 0,04137749 0,04402832 ! sarcomere GO:0030017 75 69 0,000 0,04137749 0,0440152 ! cAMP-mediated signaling GO:0019933 72 69 0,000 0,04137749 0,04400209 ! axon guidance GO:0007411 74 69 0,000 0,04137749 0,04398899 ! focal adhesion GO:0005925 75 69 0,000 0,04137749 0,0439759 ! regulation of DNA binding GO:0051101 72 70 0,000 0,0419658 0,04458789 ! carboxylic acid transmembrane transporter activity GO:0046943 71 70 0,000 0,0419658 0,04457463 ! response to hypoxia GO:0001666 76 70 0,000 0,0419658 0,04456137 ! rRNA processing GO:0006364 70 70 0,000 0,0419658 0,04454812 ! cytosolic ribosome GO:0022626 70 70 0,000 0,0419658 0,04453489 ! cell cortex GO:0005938 74 70 0,000 0,0419658 0,04452165 ! cell-matrix adhesion GO:0007160 76 71 0,000 0,0425538 0,04513205 ! response to oxygen levels GO:0070482 77 71 0,000 0,0425538 0,04511865 ! mitochondrial outer membrane GO:0005741 75 71 0,000 0,0425538 0,04510526 ! defense response to bacterium GO:0042742 71 71 0,000 0,0425538 0,04509187 ! steroid biosynthetic process GO:0006694 72 71 0,000 0,0425538 0,0450785 ! monosaccharide catabolic process GO:0046365 72 71 0,000 0,0425538 0,04506513 ! regulation of synaptic transmission GO:0050804 73 71 0,000 0,0425538 0,04505177 ! reproductive structure development GO:0048608 71 71 0,000 0,0425538 0,04503841 ! neurotransmitter transport GO:0006836 73 71 0,000 0,0425538 0,04502507 ! regulation of actin filament-based process GO:0032970 77 71 0,000 0,0425538 0,04501173 ! organic acid transmembrane transporter activity GO:0005342 72 71 0,000 0,0425538 0,0449984 ! phospholipase activity GO:0004620 75 71 0,000 0,0425538 0,04498508 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 75 71 0,000 0,0425538 0,04497177 ! cell projection part GO:0044463 75 71 0,000 0,0425538 0,04495846 ! amine biosynthetic process GO:0009309 75 72 0,000 0,04314147 0,04556586 ! meiosis GO:0007126 73 72 0,000 0,04314147 0,04555239 GO:0051327|M phase of meiotic cell cycle, ! elevation of cytosolic calcium ion concentration GO:0007204 77 72 0,000 0,04314147 0,04553892 ! acute inflammatory response GO:0002526 76 72 0,000 0,04314147 0,04552547 ! cholesterol metabolic process GO:0008203 74 72 0,000 0,04314147 0,04551202 ! lipid transporter activity GO:0005319 77 72 0,000 0,04314147 0,04549858 ! regulation of ubiquitin-protein ligase activity GO:0051438 74 72 0,000 0,04314147 0,04548514 ! cell-substrate adherens junction GO:0005924 78 72 0,000 0,04314147 0,04547172 ! negative regulation of transport GO:0051051 74 73 0,000 0,04372882 0,04607719 ! vacuolar membrane GO:0005774 74 73 0,000 0,04372882 0,0460636 ! rRNA metabolic process GO:0016072 73 73 0,000 0,04372882 0,04605002 ! meiotic cell cycle GO:0051321 75 73 0,000 0,04372882 0,04603644 ! negative regulation of organelle organization GO:0010639 78 73 0,000 0,04372882 0,04602287 ! regulation of protein transport GO:0051223 77 73 0,000 0,04372882 0,04600931 GO:0070201|regulation of establishment of protein localization, ! exopeptidase activity GO:0008238 78 73 0,000 0,04372882 0,04599576 ! cytosolic calcium ion homeostasis GO:0051480 78 73 0,000 0,04372882 0,04598222 ! hormone receptor binding GO:0051427 75 73 0,000 0,04372882 0,04596868 ! nucleosome organization GO:0034728 76 74 0,000 0,04431585 0,04657207 ! neuropeptide signaling pathway GO:0007218 79 74 0,000 0,04431585 0,04655837 ! pore complex GO:0046930 78 74 0,000 0,04431585 0,04654467 ! protein localization in nucleus GO:0034504 78 74 0,000 0,04431585 0,04653099 ! myofibril GO:0030016 80 74 0,000 0,04431585 0,04651731 ! apical junction complex GO:0043296 74 74 0,000 0,04431585 0,04650364 ! cellular carbohydrate catabolic process GO:0044275 75 74 0,000 0,04431585 0,04648998 ! development of primary sexual characteristics GO:0045137 74 74 0,000 0,04431585 0,04647633 ! membrane raft GO:0045121 78 74 0,000 0,04431585 0,04646268 ! regulation of Rho protein signal transduction GO:0035023 79 74 0,000 0,04431585 0,04644904 ! cellular response to hormone stimulus GO:0032870 81 74 0,000 0,04431585 0,04643541 ! serine-type endopeptidase inhibitor activity GO:0004867 75 74 0,000 0,04431585 0,04642179 ! nuclear chromosome part GO:0044454 76 74 0,000 0,04431585 0,04640818 ! response to drug GO:0042493 77 75 0,000 0,04490256 0,0470088 ! regulation of catabolic process GO:0009894 80 75 0,000 0,04490256 0,04699503 ! cell-substrate junction GO:0030055 82 75 0,000 0,04490256 0,04698126 ! positive regulation of cell activation GO:0050867 80 75 0,000 0,04490256 0,04696749 GO:0002696|positive regulation of leukocyte activation, ! membrane lipid biosynthetic process GO:0046467 77 75 0,000 0,04490256 0,04695374 ! tube morphogenesis GO:0035239 79 75 0,000 0,04490256 0,04694 ! cellular lipid catabolic process GO:0044242 77 75 0,000 0,04490256 0,04692626 ! structural constituent of cytoskeleton GO:0005200 81 75 0,000 0,04490256 0,04691253 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 80 76 0,000 0,04548895 0,04751127 ! regulation of ligase activity GO:0051340 78 76 0,000 0,04548895 0,04749738 ! inorganic anion transport GO:0015698 78 76 0,000 0,04548895 0,04748349 ! chromosome, centromeric region GO:0000775 78 76 0,000 0,04548895 0,04746962 ! apicolateral plasma membrane GO:0016327 76 76 0,000 0,04548895 0,04745575 ! T cell activation GO:0042110 82 76 0,000 0,04548895 0,04744189 ! digestion GO:0007586 80 76 0,000 0,04548895 0,04742804 ! cell-substrate adhesion GO:0031589 81 76 0,000 0,04548895 0,04741419 ! cilium GO:0005929 77 76 0,000 0,04548895 0,04740036 ! contractile fiber part GO:0044449 82 76 0,000 0,04548895 0,04738653 ! regulation of adenylate cyclase activity GO:0045761 80 77 0,000 0,04607501 0,04798305 ! nuclear speck GO:0016607 80 77 0,000 0,04607501 0,04796906 ! G-protein-coupled receptor binding GO:0001664 78 77 0,000 0,04607501 0,04795508 ! endonuclease activity GO:0004519 80 77 0,000 0,04607501 0,04794111 ! regulation of transmission of nerve impulse GO:0051969 79 77 0,000 0,04607501 0,04792714 ! hydrogen ion transmembrane transporter activity GO:0015078 78 77 0,000 0,04607501 0,04791318 ! extracellular matrix structural constituent GO:0005201 80 77 0,000 0,04607501 0,04789924 ! vacuolar part GO:0044437 78 77 0,000 0,04607501 0,0478853 ! thiolester hydrolase activity GO:0016790 81 78 0,000 0,04666076 0,04847995 ! potassium channel complex GO:0034705 81 78 0,000 0,04666076 0,04846585 GO:0008076|voltage-gated potassium channel complex, ! regulation of cell adhesion GO:0030155 82 78 0,000 0,04666076 0,04845176 ! cofactor biosynthetic process GO:0051188 81 78 0,000 0,04666076 0,04843767 ! blood coagulation GO:0007596 81 78 0,000 0,04666076 0,04842359 GO:0050817|coagulation, ! phospholipid biosynthetic process GO:0008654 83 79 0,000 0,04724619 0,0490169 ! biogenic amine metabolic process GO:0006576 85 79 0,000 0,04724619 0,04900266 ! phosphoric diester hydrolase activity GO:0008081 82 79 0,000 0,04724619 0,04898843 ! positive regulation of MAP kinase activity GO:0043406 85 79 0,000 0,04724619 0,04897421 ! regulation of cyclase activity GO:0031279 82 79 0,000 0,04724619 0,04896 ! regulation of neuron differentiation GO:0045664 82 79 0,000 0,04724619 0,04894579 ! regulation of cAMP biosynthetic process GO:0030817 82 79 0,000 0,04724619 0,0489316 ! exocytosis GO:0006887 81 79 0,000 0,04724619 0,04891741 ! nitrogen compound catabolic process GO:0044270 89 79 0,000 0,04724619 0,04890323 ! regulation of protein localization GO:0032880 83 79 0,000 0,04724619 0,04888906 ! alcohol catabolic process GO:0046164 83 80 0,000 0,0478313 0,04948018 ! regulation of cell cycle process GO:0010564 84 80 0,000 0,0478313 0,04946585 ! negative regulation of growth GO:0045926 84 80 0,000 0,0478313 0,04945153 ! regulation of Ras GTPase activity GO:0032318 84 80 0,000 0,0478313 0,04943722 ! regulation of lyase activity GO:0051339 83 80 0,000 0,0478313 0,04942291 ! ATP biosynthetic process GO:0006754 85 80 0,000 0,0478313 0,04940861 ! one-carbon metabolic process GO:0006730 87 80 0,000 0,0478313 0,04939433 ! monooxygenase activity GO:0004497 82 80 0,000 0,0478313 0,04938005 ! condensed chromosome GO:0000793 82 80 0,000 0,0478313 0,04936577 ! contractile fiber GO:0043292 86 80 0,000 0,0478313 0,04935151 ! protein ubiquitination GO:0016567 86 80 0,000 0,0478313 0,04933726 ! cellular carbohydrate biosynthetic process GO:0034637 83 81 0,000 0,04841609 0,04992604 ! sterol metabolic process GO:0016125 83 81 0,000 0,04841609 0,04991162 ! regulation of cAMP metabolic process GO:0030814 84 81 0,000 0,04841609 0,04989722 ! protein binding, bridging GO:0030674 86 81 0,000 0,04841609 0,04988282 ! regulation of neurological system process GO:0031644 83 81 0,000 0,04841609 0,04986844 ! protein transporter activity GO:0008565 85 82 0,000 0,04900056 0,05045589 ! positive regulation of immune response GO:0050778 91 82 0,000 0,04900056 0,05044134 ! regulation of defense response GO:0031347 82 82 0,000 0,04900056 0,05042681 ! carboxylesterase activity GO:0004091 86 82 0,000 0,04900056 0,05041228 ! transcription initiation GO:0006352 86 82 0,000 0,04900056 0,05039776 ! organelle outer membrane GO:0031968 87 83 0,000 0,04958472 0,05098388 ! cell leading edge GO:0031252 90 83 0,000 0,04958472 0,05096921 ! SH3 domain binding GO:0017124 97 83 0,000 0,04958472 0,05095454 ! hemostasis GO:0007599 86 83 0,000 0,04958472 0,05093988 ! oxidative phosphorylation GO:0006119 83 83 0,000 0,04958472 0,05092523 ! heparin binding GO:0008201 90 83 0,000 0,04958472 0,05091059 ! amine transport GO:0015837 83 83 0,000 0,04958472 0,05089595 ! extracellular matrix part GO:0044420 85 83 0,000 0,04958472 0,05088133 ! phosphoinositide binding GO:0035091 90 83 0,000 0,04958472 0,05086671 ! regulation of nucleotide biosynthetic process GO:0030808 87 84 0,000 0,05016855 0,05145086 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 85 84 0,000 0,05016855 0,05143609 GO:0010498|proteasomal protein catabolic process, ! Ras GTPase activator activity GO:0005099 89 84 0,000 0,05016855 0,05142132 ! regulation of membrane potential GO:0042391 92 84 0,000 0,05016855 0,05140657 ! perinuclear region of cytoplasm GO:0048471 91 85 0,000 0,05075206 0,05198956 ! cellular respiration GO:0045333 85 85 0,000 0,05075206 0,05197465 ! transmembrane receptor protein kinase activity GO:0019199 88 85 0,000 0,05075206 0,05195975 ! outer membrane GO:0019867 89 85 0,000 0,05075206 0,05194486 ! DNA recombination GO:0006310 86 85 0,000 0,05075206 0,05192998 ! neurotransmitter receptor activity GO:0030594 86 85 0,000 0,05075206 0,0519151 ! leukocyte differentiation GO:0002521 95 86 0,000 0,05133526 0,05249662 ! Golgi vesicle transport GO:0048193 86 86 0,000 0,05133526 0,05248159 ! pigment granule GO:0048770 90 86 0,000 0,05133526 0,05246657 GO:0042470|melanosome, ! neurotransmitter binding GO:0042165 88 86 0,000 0,05133526 0,05245156 ! anion binding GO:0043168 89 86 0,000 0,05133526 0,05243656 ! sex differentiation GO:0007548 86 86 0,000 0,05133526 0,05242156 ! UDP-glycosyltransferase activity GO:0008194 91 86 0,000 0,05133526 0,05240658 ! spindle GO:0005819 89 87 0,000 0,05191814 0,05298647 ! microtubule cytoskeleton organization GO:0000226 92 87 0,000 0,05191814 0,05297133 ! cell cycle arrest GO:0007050 92 87 0,000 0,05191814 0,0529562 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 93 87 0,000 0,05191814 0,05294108 ! regulation of cyclic nucleotide metabolic process GO:0030799 90 87 0,000 0,05191814 0,05292597 ! protein processing GO:0016485 92 87 0,000 0,05191814 0,05291086 ! ATP-dependent helicase activity GO:0008026 92 88 0,000 0,05250069 0,0534893 GO:0070035|purine NTP-dependent helicase activity, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 89 88 0,000 0,05250069 0,05347404 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 89 88 0,000 0,05250069 0,05345879 ! skeletal muscle tissue development GO:0007519 92 88 0,000 0,05250069 0,05344355 GO:0060538|skeletal muscle organ development, ! lipase activity GO:0016298 92 88 0,000 0,05250069 0,05342832 ! detection of stimulus GO:0051606 90 88 0,000 0,05250069 0,0534131 ! carboxylic acid catabolic process GO:0046395 93 89 0,000 0,05308293 0,05399008 GO:0016054|organic acid catabolic process, ! sulfur metabolic process GO:0006790 90 89 0,000 0,05308293 0,0539747 ! negative regulation of multicellular organismal process GO:0051241 93 89 0,000 0,05308293 0,05395934 ! regulation of binding GO:0051098 93 90 0,000 0,05366486 0,05453535 ! intermediate filament GO:0005882 92 90 0,000 0,05366486 0,05451983 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 95 90 0,000 0,05366486 0,05450432 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! external side of plasma membrane GO:0009897 99 90 0,000 0,05366486 0,05448883 ! growth factor binding GO:0019838 92 90 0,000 0,05366486 0,05447334 ! regulation of nucleotide metabolic process GO:0006140 93 90 0,000 0,05366486 0,05445786 ! adherens junction GO:0005912 96 90 0,000 0,05366486 0,05444239 ! ATP metabolic process GO:0046034 96 91 0,000 0,05424646 0,05501679 ! homophilic cell adhesion GO:0007156 93 91 0,000 0,05424646 0,05500117 ! ribonucleoside triphosphate biosynthetic process GO:0009201 97 91 0,000 0,05424646 0,05498556 ! protein modification by small protein conjugation GO:0032446 98 91 0,000 0,05424646 0,05496995 ! forebrain development GO:0030900 95 91 0,000 0,05424646 0,05495436 ! carbohydrate biosynthetic process GO:0016051 93 91 0,000 0,05424646 0,05493877 ! apical plasma membrane GO:0016324 96 91 0,000 0,05424646 0,0549232 ! intermediate filament cytoskeleton GO:0045111 93 91 0,000 0,05424646 0,05490763 ! glycerophospholipid metabolic process GO:0006650 98 92 0,000 0,05482775 0,05548027 ! nucleoside triphosphate biosynthetic process GO:0009142 98 92 0,000 0,05482775 0,05546456 ! clathrin-coated vesicle GO:0030136 100 92 0,000 0,05482775 0,05544885 ! protein tyrosine phosphatase activity GO:0004725 104 92 0,000 0,05482775 0,05543315 ! gland development GO:0048732 95 92 0,000 0,05482775 0,05541746 ! DNA packaging GO:0006323 94 92 0,000 0,05482775 0,05540178 ! anatomical structure homeostasis GO:0060249 96 93 0,000 0,05540872 0,05597299 ! receptor complex GO:0043235 97 93 0,000 0,05540872 0,05595716 ! voltage-gated potassium channel activity GO:0005249 99 93 0,000 0,05540872 0,05594134 ! hormone metabolic process GO:0042445 96 93 0,000 0,05540872 0,05592553 ! translational elongation GO:0006414 97 94 0,000 0,05598937 0,05649563 ! nucleotidyltransferase activity GO:0016779 96 94 0,000 0,05598937 0,05647967 ! metalloendopeptidase activity GO:0004222 105 94 0,000 0,05598937 0,05646372 ! carbohydrate catabolic process GO:0016052 95 94 0,000 0,05598937 0,05644778 ! protein maturation GO:0051604 99 94 0,000 0,05598937 0,05643185 ! solute:cation symporter activity GO:0015294 95 94 0,000 0,05598937 0,05641592 ! carboxylic acid binding GO:0031406 99 95 0,000 0,0565697 0,0569846 ! regulation of response to external stimulus GO:0032101 97 95 0,000 0,0565697 0,05696853 ! response to virus GO:0009615 102 95 0,000 0,0565697 0,05695247 ! peroxisome GO:0005777 97 96 0,000 0,05714972 0,0575202 GO:0042579|microbody, ! integral to organelle membrane GO:0031301 96 96 0,000 0,05714972 0,05750399 ! Wnt receptor signaling pathway GO:0016055 104 96 0,000 0,05714972 0,05748779 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 97 96 0,000 0,05714972 0,0574716 ! response to nutrient levels GO:0031667 98 96 0,000 0,05714972 0,05745542 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 101 97 0,000 0,05772942 0,05802189 ! microtubule associated complex GO:0005875 104 97 0,000 0,05772942 0,05800556 ! peptidyl-amino acid modification GO:0018193 99 97 0,000 0,05772942 0,05798924 ! anchoring junction GO:0070161 103 97 0,000 0,05772942 0,05797294 ! reproductive developmental process GO:0003006 97 97 0,000 0,05772942 0,05795664 ! regulation of GTPase activity GO:0043087 104 97 0,000 0,05772942 0,05794035 ! unfolded protein binding GO:0051082 100 98 0,000 0,0583088 0,05850541 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 99 98 0,000 0,0583088 0,05848897 ! polysaccharide metabolic process GO:0005976 102 98 0,000 0,0583088 0,05847255 ! protein modification by small protein conjugation or removal GO:0070647 105 98 0,000 0,0583088 0,05845613 ! chromatin binding GO:0003682 102 99 0,000 0,05888787 0,05902009 ! nuclear chromosome GO:0000228 102 99 0,000 0,05888787 0,05900353 ! regulation of cellular component biogenesis GO:0044087 106 99 0,000 0,05888787 0,05898698 ! anterior/posterior pattern formation GO:0009952 102 99 0,000 0,05888787 0,05897044 ! Ras protein signal transduction GO:0007265 105 99 0,000 0,05888787 0,05895391 ! tRNA metabolic process GO:0006399 101 100 0,000 0,05946662 0,05951662 ! protein polymerization GO:0051258 114 100 0,000 0,05946662 0,05949995 ! regulation of cell morphogenesis GO:0022604 104 100 0,000 0,05946662 0,05948328 ! chromatin assembly or disassembly GO:0006333 104 100 0,000 0,05946662 0,05946662