pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/29110-3-real-Parker_GPL887-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL887.an.zip classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! midbody GO:0030496 14 12 2,000 2,28E-07 8,318E-04 ! spindle microtubule GO:0005876 27 18 2,000 8,423E-07 1,536E-03 ! microtubule organizing center part GO:0044450 46 32 2,000 5,071E-06 6,167E-03 ! cysteine-type endopeptidase inhibitor activity GO:0004869 35 33 2,000 5,574E-06 5,084E-03 ! chaperone-mediated protein complex assembly GO:0051131 5 5 1,000 1,082E-05 7,897E-03 ! nitric-oxide synthase regulator activity GO:0030235 6 5 1,000 1,082E-05 6,581E-03 ! Golgi to plasma membrane transport GO:0006893 7 5 1,000 1,082E-05 5,64E-03 ! RNA polymerase II carboxy-terminal domain kinase activity GO:0008353 5 5 1,000 1,082E-05 4,935E-03 ! positive regulation of cell cycle GO:0045787 56 43 2,000 1,252E-05 5,076E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 1,622E-05 5,919E-03 ! establishment of chromosome localization GO:0051303 15 6 1,000 1,622E-05 5,381E-03 GO:0050000|chromosome localization, ! cytoplasmic microtubule GO:0005881 7 7 1,000 2,27E-05 6,901E-03 ! positive regulation of mitotic cell cycle GO:0045931 7 7 1,000 2,27E-05 6,37E-03 ! centriolar satellite GO:0034451 10 7 1,000 2,27E-05 5,915E-03 ! fibrinogen complex GO:0005577 7 7 1,000 2,27E-05 5,521E-03 ! spindle checkpoint GO:0031577 7 7 1,000 2,27E-05 5,176E-03 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 8 1,000 3,025E-05 6,491E-03 ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 1,000 3,025E-05 6,13E-03 ! caspase inhibitor activity GO:0043027 9 9 1,000 3,886E-05 7,462E-03 ! response to unfolded protein GO:0006986 66 64 2,000 4,168E-05 7,602E-03 ! response to protein stimulus GO:0051789 73 70 2,000 5,454E-05 9,474E-03 ! centriole GO:0005814 11 11 1,000 5,93E-05 9,833E-03 ! negative regulation of caspase activity GO:0043154 12 11 1,000 5,93E-05 9,405E-03 ! cell-matrix adhesion GO:0007160 102 74 2,000 6,441E-05 9,79E-03 ! regulation of exit from mitosis GO:0007096 31 12 1,000 7,111E-05 0,01037694 ! extracellular matrix structural constituent GO:0005201 96 78 2,000 7,538E-05 0,01057655 ! cell-substrate adhesion GO:0031589 109 80 2,000 8,13E-05 0,01098436 ! interphase of mitotic cell cycle GO:0051329 100 81 2,000 8,437E-05 0,01099196 ! heparin binding GO:0008201 108 82 2,000 8,751E-05 0,01100845 ! interphase GO:0051325 103 83 2,000 9,073E-05 0,01103303 ! negative regulation of peptidase activity GO:0010466 16 14 1,000 9,793E-05 0,0115236 ! cyclin-dependent protein kinase regulator activity GO:0016538 14 14 1,000 9,793E-05 0,01116349 ! spindle GO:0005819 126 92 2,000 1,233E-04 0,01362493 ! G2/M transition of mitotic cell cycle GO:0000086 22 16 1,000 1,29E-04 0,01383739 ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 17 1,000 1,461E-04 0,01522454 ! cellular response to unfolded protein GO:0034620 21 19 1,000 1,834E-04 0,01858705 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptide cross-linking GO:0018149 23 19 1,000 1,834E-04 0,01808469 ! post-Golgi vesicle-mediated transport GO:0006892 23 19 1,000 1,834E-04 0,01760878 ! chaperone binding GO:0051087 21 20 1,000 2,037E-04 0,01905142 ! regulation of nitric oxide biosynthetic process GO:0045428 21 20 1,000 2,037E-04 0,01857514 ! mitochondrial membrane organization GO:0007006 25 23 1,000 2,707E-04 0,02408464 ! positive regulation of nuclear division GO:0051785 35 23 1,000 2,707E-04 0,0235112 GO:0045840|positive regulation of mitosis, ! caspase regulator activity GO:0043028 26 24 1,000 2,951E-04 0,02503605 ! response to endoplasmic reticulum stress GO:0034976 30 26 1,000 3,471E-04 0,02877395 ! collagen binding GO:0005518 29 27 1,000 3,746E-04 0,03036583 ! fat cell differentiation GO:0045444 30 27 1,000 3,746E-04 0,0297057 ! cyclin-dependent protein kinase activity GO:0004693 28 27 1,000 3,746E-04 0,02907366 ! ER-nuclear signaling pathway GO:0006984 32 29 1,000 4,327E-04 0,03288659 ! acute-phase response GO:0006953 44 30 1,000 4,633E-04 0,03449443 ! response to calcium ion GO:0051592 34 31 1,000 4,95E-04 0,03611275 ! platelet alpha granule lumen GO:0031093 35 33 1,000 5,613E-04 0,04014995 ! negative regulation of hydrolase activity GO:0051346 36 34 1,000 5,96E-04 0,04181216 ! vesicle lumen GO:0031983 38 35 1,000 6,317E-04 0,04348165 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! collagen GO:0005581 54 35 1,000 6,317E-04 0,04267644 ! cytokinesis GO:0000910 38 35 1,000 6,317E-04 0,0419005 ! keratin filament GO:0045095 44 41 1,000 8,673E-04 0,05649657 ! ER-Golgi intermediate compartment GO:0005793 52 42 1,000 9,101E-04 0,05824337 ! mitochondrial transport GO:0006839 45 42 1,000 9,101E-04 0,05723917 ! G1/S transition of mitotic cell cycle GO:0000082 54 43 1,000 9,538E-04 0,05897608 ! platelet alpha granule GO:0031091 49 45 1,000 1,044E-03 0,06349916 ! response to UV GO:0009411 59 45 1,000 1,044E-03 0,06245819 ! microtubule binding GO:0008017 61 47 1,000 1,139E-03 0,06701346 ! morphogenesis of a branching structure GO:0001763 70 47 1,000 1,139E-03 0,06594975 ! regulation of cell shape GO:0008360 55 48 1,000 1,188E-03 0,06769851 ! establishment of organelle localization GO:0051656 58 48 1,000 1,188E-03 0,066657 ! cytokine-mediated signaling pathway GO:0019221 56 50 1,000 1,288E-03 0,07120102 ! positive regulation of organelle organization GO:0010638 69 51 1,000 1,34E-03 0,07295439 ! regulation of cyclin-dependent protein kinase activity GO:0000079 55 51 1,000 1,34E-03 0,07188153 ! regulation of mitosis GO:0007088 79 55 1,000 1,557E-03 0,08229656 GO:0051783|regulation of nuclear division, ! chromosome segregation GO:0007059 92 57 1,000 1,671E-03 0,08707297 ! organelle localization GO:0051640 70 59 1,000 1,789E-03 0,09191458 ! cell cycle checkpoint GO:0000075 91 60 1,000 1,849E-03 0,09370346 ! response to metal ion GO:0010038 65 60 1,000 1,849E-03 0,09241985 ! regulation of caspase activity GO:0043281 78 60 1,000 1,849E-03 0,09117093 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 77 62 1,000 1,973E-03 0,09598192 ! positive regulation of protein amino acid phosphorylation GO:0001934 72 62 1,000 1,973E-03 0,094719 ! skeletal system morphogenesis GO:0048705 83 62 1,000 1,973E-03 0,09348888 ! regulation of endopeptidase activity GO:0052548 81 63 1,000 2,037E-03 0,09525526 ! response to inorganic substance GO:0010035 71 65 1,000 2,166E-03 0,1000373 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 80 65 1,000 2,166E-03 0,09878683 ! tubulin binding GO:0015631 92 66 1,000 2,233E-03 0,10055188 ! protein kinase regulator activity GO:0019887 74 66 1,000 2,233E-03 0,09932564 ! regulation of peptidase activity GO:0052547 86 67 1,000 2,3E-03 0,10108362 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 83 67 1,000 2,3E-03 0,09988024 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 84 68 1,000 2,368E-03 0,10163122 ! positive regulation of ligase activity GO:0051351 86 70 1,000 2,507E-03 0,10635441 ! positive regulation of phosphorylation GO:0042327 82 70 1,000 2,507E-03 0,10513195 ! positive regulation of phosphorus metabolic process GO:0010562 85 72 1,000 2,65E-03 0,10986505 GO:0045937|positive regulation of phosphate metabolic process, ! acute inflammatory response GO:0002526 91 72 1,000 2,65E-03 0,10863061 ! regulation of cell cycle process GO:0010564 113 75 1,000 2,872E-03 0,11640422 ! regulation of ubiquitin-protein ligase activity GO:0051438 92 75 1,000 2,872E-03 0,11512506 ! neuropeptide signaling pathway GO:0007218 85 76 1,000 2,948E-03 0,11687661 ! kinase regulator activity GO:0019207 93 76 1,000 2,948E-03 0,11561987 ! regulation of ligase activity GO:0051340 95 78 1,000 3,102E-03 0,12037678 ! positive regulation of protein modification process GO:0031401 100 78 1,000 3,102E-03 0,11910966 ! SH3 domain binding GO:0017124 95 80 1,000 3,26E-03 0,12387276 ! chromosome, centromeric region GO:0000775 119 80 1,000 3,26E-03 0,12259572 ! ossification GO:0001503 111 82 1,000 3,422E-03 0,12736425 ! mitochondrion organization GO:0007005 104 82 1,000 3,422E-03 0,12607774 ! bone development GO:0060348 112 83 1,000 3,504E-03 0,12781714 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 101 83 1,000 3,504E-03 0,12655162 GO:0010498|proteasomal protein catabolic process, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 94 84 1,000 3,587E-03 0,12828526 ! Golgi vesicle transport GO:0048193 98 86 1,000 3,756E-03 0,13302846 ! pigment granule GO:0048770 101 87 1,000 3,842E-03 0,13476318 GO:0042470|melanosome, ! regulation of cell morphogenesis GO:0022604 100 87 1,000 3,842E-03 0,13347972 ! protein kinase binding GO:0019901 115 89 1,000 4,017E-03 0,13822882 ! response to virus GO:0009615 109 90 1,000 4,105E-03 0,13995971 ! extracellular matrix part GO:0044420 111 90 1,000 4,105E-03 0,13866378 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 111 92 1,000 4,285E-03 0,14341745 ! homophilic cell adhesion GO:0007156 107 95 1,000 4,562E-03 0,15129537 ! intermediate filament GO:0005882 102 98 1,000 4,847E-03 0,15929766 GO:0045111|intermediate filament cytoskeleton, ! unfolded protein binding GO:0051082 118 100 1,000 5,042E-03 0,16420899 ! response to light stimulus GO:0009416 131 100 1,000 5,042E-03 0,16275581 ! positive regulation of epidermal growth factor receptor activity GO:0045741 6 5 0,000 5,331E-03 0,17059349 ! negative regulation of S phase of mitotic cell cycle GO:0045749 5 5 0,000 5,331E-03 0,16911007 ! positive regulation of fatty acid biosynthetic process GO:0045723 5 5 0,000 5,331E-03 0,16765222 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 6 5 0,000 5,331E-03 0,1662193 ! response to superoxide GO:0000303 5 5 0,000 5,331E-03 0,16481066 ! negative regulation of small GTPase mediated signal transduction GO:0051058 6 5 0,000 5,331E-03 0,1634257 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 6 5 0,000 5,331E-03 0,16206382 GO:0032479|regulation of type I interferon production, ! regulation of hormone biosynthetic process GO:0046885 5 5 0,000 5,331E-03 0,16072445 ! calcium:cation antiporter activity GO:0015368 5 5 0,000 5,331E-03 0,15940703 ! quinolinate metabolic process GO:0046874 5 5 0,000 5,331E-03 0,15811104 ! biotin binding GO:0009374 7 5 0,000 5,331E-03 0,15683595 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 5,331E-03 0,15558126 ! tongue development GO:0043586 6 5 0,000 5,331E-03 0,15434649 ! nose development GO:0043584 5 5 0,000 5,331E-03 0,15313117 ! cell proliferation in forebrain GO:0021846 5 5 0,000 5,331E-03 0,15193483 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 5 5 0,000 5,331E-03 0,15075704 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 5,331E-03 0,14959737 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 5 0,000 5,331E-03 0,14845541 ! drug:hydrogen antiporter activity GO:0015307 6 5 0,000 5,331E-03 0,14733074 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! nuclear mRNA 3'-splice site recognition GO:0000389 6 5 0,000 5,331E-03 0,14622299 ! glycolipid transport GO:0046836 6 5 0,000 5,331E-03 0,14513178 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 6 5 0,000 5,331E-03 0,14405673 ! regulation of respiratory gaseous exchange GO:0043576 6 5 0,000 5,331E-03 0,14299749 ! regulation of protein export from nucleus GO:0046825 5 5 0,000 5,331E-03 0,14195371 ! neuron adhesion GO:0007158 5 5 0,000 5,331E-03 0,14092506 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 5 5 0,000 5,331E-03 0,13991121 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 5 0,000 5,331E-03 0,13891184 ! opioid peptide activity GO:0001515 6 5 0,000 5,331E-03 0,13792665 ! selenocysteine incorporation GO:0001514 5 5 0,000 5,331E-03 0,13695534 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 6 5 0,000 5,331E-03 0,13599761 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 8 5 0,000 5,331E-03 0,13505318 ! cardiac muscle cell proliferation GO:0060038 6 5 0,000 5,331E-03 0,13412178 GO:0014855|striated muscle cell proliferation, ! dsRNA fragmentation GO:0031050 6 5 0,000 5,331E-03 0,13320314 GO:0035196|gene silencing by miRNA, production of miRNAs, GO:0035195|gene silencing by miRNA, ! ruffle membrane GO:0032587 6 5 0,000 5,331E-03 0,13229699 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 5,331E-03 0,1314031 ! negative regulation of receptor-mediated endocytosis GO:0048261 7 5 0,000 5,331E-03 0,1305212 ! clathrin coat assembly GO:0048268 6 5 0,000 5,331E-03 0,12965105 ! cerebral cortex cell migration GO:0021795 5 5 0,000 5,331E-03 0,12879244 ! eukaryotic translation elongation factor 1 complex GO:0005853 5 5 0,000 5,331E-03 0,12794512 ! membrane hyperpolarization GO:0060081 5 5 0,000 5,331E-03 0,12710888 ! regulation of striated muscle cell differentiation GO:0051153 6 5 0,000 5,331E-03 0,12628349 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 5,331E-03 0,12546876 ! translation repressor activity GO:0030371 8 5 0,000 5,331E-03 0,12466447 ! positive regulation of muscle cell differentiation GO:0051149 6 5 0,000 5,331E-03 0,12387043 ! smooth muscle cell differentiation GO:0051145 6 5 0,000 5,331E-03 0,12308644 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 5 5 0,000 5,331E-03 0,12231232 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 5,331E-03 0,12154786 GO:0046329|negative regulation of JNK cascade, ! double-stranded telomeric DNA binding GO:0003691 6 5 0,000 5,331E-03 0,12079291 ! negative regulation of heart contraction GO:0045822 5 5 0,000 5,331E-03 0,12004727 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 5,331E-03 0,11931079 ! microfibril GO:0001527 5 5 0,000 5,331E-03 0,11858328 ! troponin I binding GO:0031013 5 5 0,000 5,331E-03 0,11786459 ! negative regulation of viral genome replication GO:0045071 6 5 0,000 5,331E-03 0,11715457 ! traversing start control point of mitotic cell cycle GO:0007089 6 5 0,000 5,331E-03 0,11645304 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 5,331E-03 0,11575987 ! dorsal/ventral neural tube patterning GO:0021904 5 5 0,000 5,331E-03 0,1150749 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 5,331E-03 0,11439799 ! protein lipoylation GO:0009249 14 5 0,000 5,331E-03 0,11372899 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 5,331E-03 0,11306778 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 5,331E-03 0,11241421 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of isotype switching to IgG isotypes GO:0048302 5 5 0,000 5,331E-03 0,11176815 ! transmembrane-ephrin receptor activity GO:0005005 6 5 0,000 5,331E-03 0,11112947 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 5,331E-03 0,11049806 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 5,331E-03 0,10987377 ! glutamate catabolic process GO:0006538 6 5 0,000 5,331E-03 0,10925651 ! microvillus organization GO:0032528 5 5 0,000 5,331E-03 0,10864613 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 6 5 0,000 5,331E-03 0,10804254 ! tyrosine catabolic process GO:0006572 5 5 0,000 5,331E-03 0,10744562 ! response to pH GO:0009268 5 5 0,000 5,331E-03 0,10685526 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 5 0,000 5,331E-03 0,10627136 ! regulation of protein import into nucleus, translocation GO:0033158 5 5 0,000 5,331E-03 0,10569379 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 5,331E-03 0,10512248 ! polyol biosynthetic process GO:0046173 5 5 0,000 5,331E-03 0,1045573 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 7 5 0,000 5,331E-03 0,10399817 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 5,331E-03 0,10344499 ! fibroblast growth factor receptor activity GO:0005007 6 5 0,000 5,331E-03 0,10289766 ! protein-DNA loading ATPase activity GO:0033170 6 5 0,000 5,331E-03 0,1023561 GO:0003689|DNA clamp loader activity, ! mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276 5 5 0,000 5,331E-03 0,1018202 ! anaerobic glycolysis GO:0019642 5 5 0,000 5,331E-03 0,10128989 GO:0004459|L-lactate dehydrogenase activity, ! adenosine receptor activity, G-protein coupled GO:0001609 6 5 0,000 5,331E-03 0,10076507 ! regulation of retinoic acid receptor signaling pathway GO:0048385 6 5 0,000 5,331E-03 0,10024566 ! peroxisomal matrix GO:0005782 5 5 0,000 5,331E-03 0,09973158 GO:0031907|microbody lumen, ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 5,331E-03 0,09922275 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 6 5 0,000 5,331E-03 0,09871908 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 5,331E-03 0,0982205 ! multivesicular body GO:0005771 5 5 0,000 5,331E-03 0,09772693 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 5,331E-03 0,09723829 GO:0032430|positive regulation of phospholipase A2 activity, ! paraxial mesoderm formation GO:0048341 6 5 0,000 5,331E-03 0,09675452 ! insulin-like growth factor I binding GO:0031994 6 5 0,000 5,331E-03 0,09627554 ! mitochondrial outer membrane translocase complex GO:0005742 5 5 0,000 5,331E-03 0,09580127 ! peptidyl-histidine phosphorylation GO:0018106 6 5 0,000 5,331E-03 0,09533166 ! negative regulation of lipoprotein lipase activity GO:0051005 5 5 0,000 5,331E-03 0,09486662 ! epithelial cell maturation GO:0002070 14 5 0,000 5,331E-03 0,09440611 ! positive regulation of lipoprotein lipase activity GO:0051006 6 5 0,000 5,331E-03 0,09395004 ! muscle thin filament assembly GO:0030240 5 5 0,000 5,331E-03 0,09349836 ! regulation of protein amino acid autophosphorylation GO:0031952 5 5 0,000 5,331E-03 0,093051 ! negative regulation of fatty acid metabolic process GO:0045922 14 5 0,000 5,331E-03 0,0926079 ! regulation of glycoprotein biosynthetic process GO:0010559 6 5 0,000 5,331E-03 0,092169 ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,331E-03 0,09173424 ! positive regulation of translational initiation GO:0045948 6 5 0,000 5,331E-03 0,09130356 ! nonhomologous end joining complex GO:0070419 6 5 0,000 5,331E-03 0,09087691 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! depyrimidination GO:0045008 5 5 0,000 5,331E-03 0,09045422 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 5,331E-03 0,09003545 ! ATPase activator activity GO:0001671 5 5 0,000 5,331E-03 0,08962054 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 5,331E-03 0,08920944 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! DNA damage response, signal transduction resulting in transcription GO:0042772 17 5 0,000 5,331E-03 0,08880209 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! calcium sensitive guanylate cyclase activator activity GO:0008048 5 5 0,000 5,331E-03 0,08839845 ! regulation of cholesterol biosynthetic process GO:0045540 5 5 0,000 5,331E-03 0,08799845 ! positive regulation of collagen metabolic process GO:0010714 6 5 0,000 5,331E-03 0,08760206 GO:0032967|positive regulation of collagen biosynthetic process, ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 7 5 0,000 5,331E-03 0,08720923 ! regulation of protein amino acid dephosphorylation GO:0035304 7 5 0,000 5,331E-03 0,0868199 ! cardiac myofibril assembly GO:0055003 5 5 0,000 5,331E-03 0,08643404 ! anterograde axon cargo transport GO:0008089 6 5 0,000 5,331E-03 0,08605158 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,331E-03 0,0856725 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 5,331E-03 0,08529675 GO:0003923|GPI-anchor transamidase activity, ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 5,331E-03 0,08492427 ! thiamin and derivative metabolic process GO:0042723 5 5 0,000 5,331E-03 0,08455504 ! protein localization to telomere GO:0070198 7 5 0,000 5,331E-03 0,084189 ! response to exogenous dsRNA GO:0043330 5 5 0,000 5,331E-03 0,08382611 ! MutSalpha complex binding GO:0032407 7 5 0,000 5,331E-03 0,08346634 ! bile acid biosynthetic process GO:0006699 5 5 0,000 5,331E-03 0,08310965 ! negative regulation of fat cell differentiation GO:0045599 6 5 0,000 5,331E-03 0,08275599 ! enucleate erythrocyte differentiation GO:0043353 7 5 0,000 5,331E-03 0,08240533 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 5,331E-03 0,08205763 ! nerve growth factor binding GO:0048406 7 5 0,000 5,331E-03 0,08171285 ! platelet-derived growth factor binding GO:0048407 8 5 0,000 5,331E-03 0,08137095 ! high-density lipoprotein binding GO:0008035 6 5 0,000 5,331E-03 0,08103191 ! negative regulation of focal adhesion formation GO:0051895 5 5 0,000 5,331E-03 0,08069568 ! transcription initiation factor activity GO:0016986 5 5 0,000 5,331E-03 0,08036222 ! gas homeostasis GO:0033483 5 5 0,000 5,331E-03 0,08003151 ! Schwann cell development GO:0014044 5 5 0,000 5,331E-03 0,07970352 ! CD4-positive, alpha beta T cell differentiation GO:0043367 5 5 0,000 5,331E-03 0,0793782 ! cyclohydrolase activity GO:0019238 5 5 0,000 5,331E-03 0,07905552 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 5,331E-03 0,07873546 ! response to pheromone GO:0019236 5 5 0,000 5,331E-03 0,07841798 GO:0016503|pheromone receptor activity, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 5 5 0,000 5,331E-03 0,07810304 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 5,331E-03 0,07779063 ! rhombomere development GO:0021546 6 5 0,000 5,331E-03 0,07748071 ! alanine transport GO:0032328 6 5 0,000 5,331E-03 0,07717325 ! superoxide-generating NADPH oxidase activity GO:0016175 5 5 0,000 5,331E-03 0,07686821 ! NAD(P)H oxidase activity GO:0016174 5 5 0,000 5,331E-03 0,07656558 ! ventral spinal cord interneuron specification GO:0021521 7 5 0,000 5,331E-03 0,07626533 GO:0021514|ventral spinal cord interneuron differentiation, GO:0060579|ventral spinal cord interneuron fate commitment, ! spinal cord motor neuron cell fate specification GO:0021520 6 5 0,000 5,331E-03 0,07596741 ! regulation of meiosis GO:0040020 6 5 0,000 5,331E-03 0,07567182 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 6 5 0,000 5,331E-03 0,07537852 GO:0000085|G2 phase of mitotic cell cycle, ! parasympathetic nervous system development GO:0048486 5 5 0,000 5,331E-03 0,07508748 ! lymphocyte costimulation GO:0031294 5 5 0,000 5,331E-03 0,07479868 GO:0031295|T cell costimulation, ! response to tumor cell GO:0002347 7 5 0,000 5,331E-03 0,0745121 ! RS domain binding GO:0050733 6 5 0,000 5,331E-03 0,0742277 ! telomerase holoenzyme complex GO:0005697 6 5 0,000 5,331E-03 0,07394547 ! negative regulation of lipoprotein metabolic process GO:0050748 6 5 0,000 5,331E-03 0,07366537 ! B cell homeostasis GO:0001782 6 5 0,000 5,331E-03 0,07338739 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 5,331E-03 0,0731115 ! anaphase GO:0051322 7 5 0,000 5,331E-03 0,07283767 GO:0000090|mitotic anaphase, ! S phase GO:0051320 5 5 0,000 5,331E-03 0,07256589 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 5,331E-03 0,07229613 GO:0050820|positive regulation of coagulation, ! ribonuclease H activity GO:0004523 14 5 0,000 5,331E-03 0,07202836 ! AP-2 adaptor complex GO:0030122 5 5 0,000 5,331E-03 0,07176258 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 6 5 0,000 5,331E-03 0,07149874 ! diuresis GO:0030146 5 5 0,000 5,331E-03 0,07123684 GO:0030147|natriuresis, ! phosphatidylcholine binding GO:0031210 5 5 0,000 5,331E-03 0,07097685 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 5,331E-03 0,07071876 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 5,331E-03 0,07046253 ! very-low-density lipoprotein particle clearance GO:0034447 6 5 0,000 5,331E-03 0,07020815 ! GTP-Rho binding GO:0017049 5 5 0,000 5,331E-03 0,0699556 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 5,331E-03 0,06970487 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 5,331E-03 0,06945592 ! chondroitin sulfotransferase activity GO:0034481 6 5 0,000 5,331E-03 0,06920875 ! brown fat cell differentiation GO:0050873 5 5 0,000 5,331E-03 0,06896333 ! regulation of telomerase activity GO:0051972 6 5 0,000 5,331E-03 0,06871964 ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 5,331E-03 0,06847767 ! TAP complex GO:0042825 5 5 0,000 5,331E-03 0,0682374 ! platelet dense granule GO:0042827 6 5 0,000 5,331E-03 0,0679988 ! bHLH transcription factor binding GO:0043425 5 5 0,000 5,331E-03 0,06776187 ! secretory granule organization GO:0033363 5 5 0,000 5,331E-03 0,06752659 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 14 5 0,000 5,331E-03 0,06729293 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 5,331E-03 0,06706089 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 5,331E-03 0,06683044 ! lamin binding GO:0005521 8 5 0,000 5,331E-03 0,06660157 ! aldehyde-lyase activity GO:0016832 6 5 0,000 5,331E-03 0,06637426 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 5,331E-03 0,0661485 ! neural plate morphogenesis GO:0001839 6 5 0,000 5,331E-03 0,06592426 ! cyclosporin A binding GO:0016018 6 5 0,000 5,331E-03 0,06570155 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 5,331E-03 0,06548033 ! negative regulation of fibrinolysis GO:0051918 5 5 0,000 5,331E-03 0,0652606 ! positive regulation of telomere maintenance GO:0032206 7 5 0,000 5,331E-03 0,06504233 ! pattern recognition receptor signaling pathway GO:0002221 5 5 0,000 5,331E-03 0,06482553 GO:0002224|toll-like receptor signaling pathway, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 5 5 0,000 5,331E-03 0,06461016 ! positive regulation of blood vessel endothelial cell migration GO:0043536 6 5 0,000 5,331E-03 0,06439622 ! flavin-containing monooxygenase activity GO:0004499 6 5 0,000 5,331E-03 0,06418369 ! regulation of calcium ion transport via store-operated calcium channel activity GO:0032234 5 5 0,000 5,331E-03 0,06397256 ! hemopoietic progenitor cell differentiation GO:0002244 6 5 0,000 5,331E-03 0,06376281 ! organ or tissue specific immune response GO:0002251 6 5 0,000 5,331E-03 0,06355444 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 5,331E-03 0,06334742 ! retina homeostasis GO:0001895 5 5 0,000 5,331E-03 0,06314175 ! prepulse inhibition GO:0060134 8 5 0,000 5,331E-03 0,0629374 ! maternal placenta development GO:0001893 5 5 0,000 5,331E-03 0,06273438 GO:0046697|decidualization, ! endothelial cell development GO:0001885 6 5 0,000 5,331E-03 0,06253266 ! regulation of growth hormone secretion GO:0060123 5 5 0,000 5,331E-03 0,06233224 GO:0060124|positive regulation of growth hormone secretion, ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 5,331E-03 0,06213309 ! thiamin pyrophosphate binding GO:0030976 5 5 0,000 5,331E-03 0,06193522 ! protein palmitoylation GO:0018345 5 5 0,000 5,331E-03 0,0617386 ! protein amino acid prenylation GO:0018346 6 5 0,000 5,331E-03 0,06154322 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 5 0,000 5,331E-03 0,06134908 ! stem cell division GO:0017145 6 5 0,000 5,331E-03 0,06115616 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 5,331E-03 0,06096445 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 6 5 0,000 5,331E-03 0,06077393 ! organ regeneration GO:0031100 6 5 0,000 5,331E-03 0,0605846 ! lymphocyte apoptosis GO:0070227 6 5 0,000 5,331E-03 0,06039645 ! positive regulation of microtubule polymerization GO:0031116 5 5 0,000 5,331E-03 0,06020947 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 5,331E-03 0,06002364 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of developmental growth GO:0048639 6 5 0,000 5,331E-03 0,05983895 ! acyl carrier activity GO:0000036 5 5 0,000 5,331E-03 0,05965539 ! positive regulation of cAMP biosynthetic process GO:0030819 6 5 0,000 5,331E-03 0,05947296 GO:0030816|positive regulation of cAMP metabolic process, ! condensin complex GO:0000796 6 5 0,000 5,331E-03 0,05929164 ! phagocytic vesicle GO:0045335 5 5 0,000 5,331E-03 0,05911142 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 5,331E-03 0,0589323 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 5,331E-03 0,05875425 GO:0030823|regulation of cGMP metabolic process, ! citrulline metabolic process GO:0000052 14 5 0,000 5,331E-03 0,05857728 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 5,331E-03 0,05840138 ! polyol transport GO:0015791 8 5 0,000 5,331E-03 0,05822652 ! post-embryonic morphogenesis GO:0009886 7 5 0,000 5,331E-03 0,05805271 ! pyrimidine nucleotide-sugar transport GO:0015781 5 5 0,000 5,331E-03 0,05787993 ! regulation of cell adhesion mediated by integrin GO:0033628 5 5 0,000 5,331E-03 0,05770818 ! cell adhesion mediated by integrin GO:0033627 5 5 0,000 5,331E-03 0,05753745 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 5,331E-03 0,05736772 ! glycerol-3-phosphate metabolic process GO:0006072 6 5 0,000 5,331E-03 0,05719899 ! ethanol metabolic process GO:0006067 6 5 0,000 5,331E-03 0,05703126 GO:0006069|ethanol oxidation, GO:0034308|monohydric alcohol metabolic process, ! phosphatidic acid metabolic process GO:0046473 5 5 0,000 5,331E-03 0,0568645 ! cobalt ion transport GO:0006824 5 5 0,000 5,331E-03 0,05669871 ! cellular zinc ion homeostasis GO:0006882 6 5 0,000 5,331E-03 0,05653389 ! syncytium formation by plasma membrane fusion GO:0000768 5 5 0,000 5,331E-03 0,05637002 GO:0007520|myoblast fusion, ! poly(U) RNA binding GO:0008266 5 5 0,000 5,331E-03 0,0562071 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 5 5 0,000 5,331E-03 0,05604512 ! sterol carrier activity GO:0005498 6 5 0,000 5,331E-03 0,05588407 ! adaptation of signaling pathway GO:0022401 6 5 0,000 5,331E-03 0,05572395 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 6 5 0,000 5,331E-03 0,05556474 ! response to acid GO:0001101 7 5 0,000 5,331E-03 0,05540643 ! fibril organization GO:0043206 5 5 0,000 5,331E-03 0,05524903 ! malate metabolic process GO:0006108 6 5 0,000 5,331E-03 0,05509252 ! regulation of dopamine uptake GO:0051584 7 5 0,000 5,331E-03 0,05493689 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! copulation GO:0007620 5 5 0,000 5,331E-03 0,05478214 ! circadian sleep/wake cycle process GO:0022410 5 5 0,000 5,331E-03 0,05462825 GO:0042749|regulation of circadian sleep/wake cycle, GO:0045187|regulation of circadian sleep/wake cycle, sleep, ! cleavage furrow GO:0032154 6 5 0,000 5,331E-03 0,05447523 ! protein maturation by protein folding GO:0022417 5 5 0,000 5,331E-03 0,05432307 ! activation of protein kinase B activity GO:0032148 15 5 0,000 5,331E-03 0,05417175 ! origin recognition complex GO:0000808 5 5 0,000 5,331E-03 0,05402127 ! neurexin binding GO:0042043 6 5 0,000 5,331E-03 0,05387163 ! sensory perception of temperature stimulus GO:0050951 8 5 0,000 5,331E-03 0,05372281 ! protein amino acid dealkylation GO:0008214 5 5 0,000 5,331E-03 0,05357482 GO:0006482|protein amino acid demethylation, ! NF-kappaB-inducing kinase activity GO:0004704 5 5 0,000 5,331E-03 0,05342763 ! lipoic acid binding GO:0031405 5 5 0,000 5,331E-03 0,05328126 ! very-low-density lipoprotein particle assembly GO:0034379 5 5 0,000 5,331E-03 0,05313568 ! lithium ion binding GO:0031403 6 5 0,000 5,331E-03 0,05299089 ! grooming behavior GO:0007625 7 5 0,000 5,331E-03 0,0528469 ! regulation of smooth muscle cell apoptosis GO:0034391 5 5 0,000 5,331E-03 0,05270368 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 5,331E-03 0,05256124 ! lymph vessel development GO:0001945 6 5 0,000 5,331E-03 0,05241956 ! bicarbonate transport GO:0015701 5 5 0,000 5,331E-03 0,05227865 ! positive regulation of cell-matrix adhesion GO:0001954 8 5 0,000 5,331E-03 0,05213849 GO:0010811|positive regulation of cell-substrate adhesion, ! response to interferon-gamma GO:0034341 6 5 0,000 5,331E-03 0,05199909 ! protein-lysine 6-oxidase activity GO:0004720 23 5 0,000 5,331E-03 0,05186042 ! endothelial cell proliferation GO:0001935 8 5 0,000 5,331E-03 0,05172249 ! polynucleotide adenylyltransferase activity GO:0004652 5 5 0,000 5,331E-03 0,0515853 ! dorsal spinal cord development GO:0021516 6 5 0,000 5,331E-03 0,05144883 ! activation of MAPKKK activity GO:0000185 5 5 0,000 5,331E-03 0,05131308 ! synaptic vesicle maturation GO:0016188 6 5 0,000 5,331E-03 0,05117805 ! sphingoid catabolic process GO:0046521 5 5 0,000 5,331E-03 0,05104372 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 5,331E-03 0,0509101 ! neutrophil mediated immunity GO:0002446 5 5 0,000 5,331E-03 0,05077718 ! intercellular canaliculus GO:0046581 5 5 0,000 5,331E-03 0,05064494 ! dopamine binding GO:0035240 7 5 0,000 5,331E-03 0,0505134 GO:0004952|dopamine receptor activity, ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 5 5 0,000 5,331E-03 0,05038253 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 5 5 0,000 5,331E-03 0,05025235 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 6 5 0,000 5,331E-03 0,05012283 ! amine oxidase activity GO:0008131 7 5 0,000 5,331E-03 0,04999398 ! monocyte activation GO:0042117 9 5 0,000 5,331E-03 0,04986579 ! negative regulation of protein binding GO:0032091 5 5 0,000 5,331E-03 0,04973826 ! regulation of response to food GO:0032095 5 5 0,000 5,331E-03 0,04961137 ! response to food GO:0032094 6 5 0,000 5,331E-03 0,04948514 ! positive regulation of protein binding GO:0032092 5 5 0,000 5,331E-03 0,04935954 ! copper ion transmembrane transporter activity GO:0005375 5 5 0,000 5,331E-03 0,04923458 ! regulation of ryanodine-sensitive calcium-release channel activity GO:0060314 6 5 0,000 5,331E-03 0,04911025 ! hedgehog receptor activity GO:0008158 5 5 0,000 5,331E-03 0,04898654 ! lipoprotein catabolic process GO:0042159 5 5 0,000 5,331E-03 0,04886346 ! substrate-bound cell migration, cell extension GO:0006930 7 5 0,000 5,331E-03 0,048741 ! purine salvage GO:0043101 7 5 0,000 5,331E-03 0,04861915 ! small-subunit processome GO:0032040 5 5 0,000 5,331E-03 0,0484979 ! positive regulation of catecholamine secretion GO:0033605 5 5 0,000 5,331E-03 0,04837726 ! ciliary rootlet GO:0035253 5 5 0,000 5,331E-03 0,04825722 ! myosin heavy chain binding GO:0032036 5 5 0,000 5,331E-03 0,04813777 ! nucleobase transport GO:0015851 5 5 0,000 5,331E-03 0,04801891 ! sodium ion transmembrane transporter activity GO:0015081 6 5 0,000 5,331E-03 0,04790064 ! GPI anchor binding GO:0034235 6 5 0,000 5,331E-03 0,04778294 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,331E-03 0,04766583 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! thrombin receptor activity GO:0015057 5 5 0,000 5,331E-03 0,04754929 ! palmitoyl-CoA hydrolase activity GO:0016290 5 5 0,000 5,331E-03 0,04743331 ! basic amino acid transport GO:0015802 5 5 0,000 5,331E-03 0,0473179 ! dendritic shaft GO:0043198 5 5 0,000 5,331E-03 0,04720305 ! terminal button GO:0043195 7 5 0,000 5,331E-03 0,04708876 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 5,331E-03 0,04697502 GO:0016274|protein-arginine N-methyltransferase activity, ! neuronal ion channel clustering GO:0045161 5 5 0,000 5,331E-03 0,04686183 ! transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity GO:0030618 6 5 0,000 5,331E-03 0,04674918 ! homeostasis of number of cells within a tissue GO:0048873 7 5 0,000 5,331E-03 0,04663707 ! negative regulation of peptide secretion GO:0002792 5 5 0,000 5,331E-03 0,0465255 GO:0046676|negative regulation of insulin secretion, ! neural nucleus development GO:0048857 6 5 0,000 5,331E-03 0,04641446 ! response to UV-C GO:0010225 15 5 0,000 5,331E-03 0,04630395 ! positive regulation of organ growth GO:0046622 5 5 0,000 5,331E-03 0,04619396 ! response to arsenic GO:0046685 6 5 0,000 5,331E-03 0,0460845 ! IgE binding GO:0019863 5 5 0,000 5,331E-03 0,04597555 ! positive regulation of T cell cytokine production GO:0002726 5 5 0,000 5,331E-03 0,04586712 GO:0032743|positive regulation of interleukin-2 production, ! transcription-coupled nucleotide-excision repair GO:0006283 5 5 0,000 5,331E-03 0,0457592 ! monoamine transmembrane transporter activity GO:0008504 6 5 0,000 5,331E-03 0,04565178 ! response to copper ion GO:0046688 5 5 0,000 5,331E-03 0,04554487 ! response to cadmium ion GO:0046686 5 5 0,000 5,331E-03 0,04543845 ! tetrahydrofolate metabolic process GO:0046653 5 5 0,000 5,331E-03 0,04533254 ! regulation of interleukin-1 beta production GO:0032651 5 5 0,000 5,331E-03 0,04522711 ! protein autoprocessing GO:0016540 6 5 0,000 5,331E-03 0,04512218 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 5,331E-03 0,04501773 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 5,331E-03 0,04491376 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 5,331E-03 0,04481027 GO:0005218|intracellular ligand-gated calcium channel activity, ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 5,331E-03 0,04470726 ! mitotic recombination GO:0006312 15 5 0,000 5,331E-03 0,04460472 ! negative regulation of interleukin-6 production GO:0032715 6 5 0,000 5,331E-03 0,04450265 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 5,331E-03 0,04440105 ! membrane to membrane docking GO:0022614 5 5 0,000 5,331E-03 0,0442999 ! regulation of transcription from RNA polymerase I promoter GO:0006356 14 5 0,000 5,331E-03 0,04419922 ! translation activator activity GO:0008494 5 5 0,000 5,331E-03 0,044099 ! somatostatin receptor activity GO:0004994 5 5 0,000 5,331E-03 0,04399923 ! melanocortin receptor activity GO:0004977 6 5 0,000 5,331E-03 0,04389991 ! serine-type carboxypeptidase activity GO:0004185 5 5 0,000 5,331E-03 0,04380103 GO:0070008|serine-type exopeptidase activity, ! protein phosphatase 2A binding GO:0051721 6 5 0,000 5,331E-03 0,0437026 ! salivary gland morphogenesis GO:0007435 5 5 0,000 5,331E-03 0,04360461 ! galactosidase activity GO:0015925 5 5 0,000 5,331E-03 0,04350707 ! prostaglandin E receptor activity GO:0004957 7 5 0,000 5,331E-03 0,04340995 ! cellular response to nutrient GO:0031670 5 5 0,000 5,331E-03 0,04331327 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 5,331E-03 0,04321702 ! L-cystine transmembrane transporter activity GO:0015184 5 5 0,000 5,331E-03 0,04312119 ! glycine transmembrane transporter activity GO:0015187 7 5 0,000 5,331E-03 0,04302579 ! L-gamma-aminobutyric acid transmembrane transporter activity GO:0015185 6 5 0,000 5,331E-03 0,04293081 ! A band GO:0031672 5 5 0,000 5,331E-03 0,04283625 ! heat generation GO:0031649 5 5 0,000 5,331E-03 0,04274211 ! flagellum organization GO:0043064 5 5 0,000 5,331E-03 0,04264837 GO:0009296|flagellum assembly, ! tricarboxylic acid cycle enzyme complex GO:0045239 6 5 0,000 5,331E-03 0,04255505 ! disaccharide metabolic process GO:0005984 6 5 0,000 5,331E-03 0,04246214 ! glycogen catabolic process GO:0005980 16 5 0,000 5,331E-03 0,04236963 ! dopamine biosynthetic process GO:0042416 6 5 0,000 5,331E-03 0,04227752 ! 5'-3' exonuclease activity GO:0008409 14 5 0,000 5,331E-03 0,04218581 ! chromocenter GO:0010369 5 5 0,000 5,331E-03 0,0420945 ! glial cell migration GO:0008347 5 5 0,000 5,331E-03 0,04200358 ! epidermal growth factor receptor binding GO:0005154 7 5 0,000 5,331E-03 0,04191306 ! calcium-dependent phospholipase A2 activity GO:0047498 5 5 0,000 5,331E-03 0,04182292 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 5,331E-03 0,04173317 ! growth hormone receptor binding GO:0005131 5 5 0,000 5,331E-03 0,04164381 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 5,331E-03 0,04155482 ! negative regulation of smooth muscle contraction GO:0045986 7 5 0,000 5,331E-03 0,04146622 ! aminomethyltransferase activity GO:0004047 5 5 0,000 5,331E-03 0,041378 ! aminoacylase activity GO:0004046 5 5 0,000 5,331E-03 0,04129014 ! penetration of zona pellucida GO:0007341 6 5 0,000 5,331E-03 0,04120267 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 5 5 0,000 5,331E-03 0,04111556 ! nucleus localization GO:0051647 5 5 0,000 5,331E-03 0,04102881 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 5 5 0,000 5,331E-03 0,04094244 ! carnitine metabolic process GO:0009437 5 5 0,000 5,331E-03 0,04085642 GO:0006577|betaine metabolic process, ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 6,394E-03 0,04890011 ! regulation of helicase activity GO:0051095 6 6 0,000 6,394E-03 0,04879781 ! response to oxygen radical GO:0000305 6 6 0,000 6,394E-03 0,04869593 ! positive regulation of axon extension GO:0045773 7 6 0,000 6,394E-03 0,04859448 ! forebrain neuron differentiation GO:0021879 6 6 0,000 6,394E-03 0,04849346 ! forebrain regionalization GO:0021871 7 6 0,000 6,394E-03 0,04839285 ! meiotic prophase I GO:0007128 7 6 0,000 6,394E-03 0,04829265 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 6,394E-03 0,04819288 ! inositol trisphosphate phosphatase activity GO:0046030 8 6 0,000 6,394E-03 0,04809351 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 6,394E-03 0,04799455 ! SMAD protein nuclear translocation GO:0007184 7 6 0,000 6,394E-03 0,047896 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 9 6 0,000 6,394E-03 0,04779785 ! carbohydrate phosphorylation GO:0046835 7 6 0,000 6,394E-03 0,04770011 ! phosphoinositide 3-kinase binding GO:0043548 6 6 0,000 6,394E-03 0,04760276 ! protein amino acid sulfation GO:0006477 9 6 0,000 6,394E-03 0,04750581 GO:0051923|sulfation, ! diphosphotransferase activity GO:0016778 7 6 0,000 6,394E-03 0,04740925 ! establishment of tissue polarity GO:0007164 8 6 0,000 6,394E-03 0,04731309 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 6,394E-03 0,04721731 ! receptor guanylyl cyclase signaling pathway GO:0007168 6 6 0,000 6,394E-03 0,04712192 ! embryonic camera-type eye development GO:0031076 9 6 0,000 6,394E-03 0,04702692 GO:0048596|embryonic camera-type eye morphogenesis, ! hexokinase activity GO:0004396 7 6 0,000 6,394E-03 0,0469323 ! regulation of mitochondrial membrane permeability GO:0046902 7 6 0,000 6,394E-03 0,04683806 ! neurofilament cytoskeleton organization GO:0060052 6 6 0,000 6,394E-03 0,04674419 ! Notch receptor processing GO:0007220 7 6 0,000 6,394E-03 0,0466507 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 8 6 0,000 6,394E-03 0,04655759 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 7 6 0,000 6,394E-03 0,04646485 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 6,394E-03 0,04637247 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 6,394E-03 0,04628046 ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 6 0,000 6,394E-03 0,04618882 ! neurofilament GO:0005883 7 6 0,000 6,394E-03 0,04609753 ! glial cell fate commitment GO:0021781 7 6 0,000 6,394E-03 0,04600661 ! cytoplasmic dynein complex GO:0005868 7 6 0,000 6,394E-03 0,04591605 ! dynactin complex GO:0005869 7 6 0,000 6,394E-03 0,04582584 ! fibroblast growth factor receptor antagonist activity GO:0030353 7 6 0,000 6,394E-03 0,04573598 GO:0005152|interleukin-1 receptor antagonist activity, ! enoyl-CoA hydratase activity GO:0004300 6 6 0,000 6,394E-03 0,04564648 ! oocyte maturation GO:0001556 6 6 0,000 6,394E-03 0,04555733 ! DNA replication origin binding GO:0003688 6 6 0,000 6,394E-03 0,04546852 ! reflex GO:0060004 10 6 0,000 6,394E-03 0,04538006 ! positive regulation of glycolysis GO:0045821 6 6 0,000 6,394E-03 0,04529195 ! parathyroid gland development GO:0060017 6 6 0,000 6,394E-03 0,04520417 ! anagen GO:0042640 7 6 0,000 6,394E-03 0,04511674 ! protein-cofactor linkage GO:0018065 15 6 0,000 6,394E-03 0,04502964 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 6 6 0,000 6,394E-03 0,04494288 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! protein targeting to ER GO:0045047 7 6 0,000 6,394E-03 0,04485645 GO:0006614|SRP-dependent cotranslational protein targeting to membrane, ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 6 6 0,000 6,394E-03 0,04477035 ! skeletal myofibril assembly GO:0014866 6 6 0,000 6,394E-03 0,04468458 ! structural constituent of tooth enamel GO:0030345 7 6 0,000 6,394E-03 0,04459914 ! cysteine metabolic process GO:0006534 7 6 0,000 6,394E-03 0,04451403 ! glycine catabolic process GO:0006546 6 6 0,000 6,394E-03 0,04442924 ! adenohypophysis development GO:0021984 6 6 0,000 6,394E-03 0,04434478 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 6 6 0,000 6,394E-03 0,04426063 ! deoxyribonucleotide biosynthetic process GO:0009263 7 6 0,000 6,394E-03 0,0441768 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 6 0,000 6,394E-03 0,04409329 ! microtubule nucleation GO:0007020 7 6 0,000 6,394E-03 0,0440101 ! proline biosynthetic process GO:0006561 8 6 0,000 6,394E-03 0,04392722 ! tryptophan metabolic process GO:0006568 6 6 0,000 6,394E-03 0,04384465 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 6 6 0,000 6,394E-03 0,04376239 ! thyroid hormone generation GO:0006590 6 6 0,000 6,394E-03 0,04368043 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 6,394E-03 0,04359879 ! retinoid X receptor binding GO:0046965 7 6 0,000 6,394E-03 0,04351745 ! proton-transporting V-type ATPase, V0 domain GO:0033179 6 6 0,000 6,394E-03 0,04343641 ! transforming growth factor beta receptor activity, type I GO:0005025 7 6 0,000 6,394E-03 0,04335567 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 6,394E-03 0,04327524 ! sister chromatid cohesion GO:0007062 6 6 0,000 6,394E-03 0,0431951 ! retinoic acid receptor signaling pathway GO:0048384 9 6 0,000 6,394E-03 0,04311525 ! positive regulation of transporter activity GO:0032411 8 6 0,000 6,394E-03 0,04303571 GO:0032414|positive regulation of ion transmembrane transporter activity, ! cerebral cortex neuron differentiation GO:0021895 7 6 0,000 6,394E-03 0,04295645 ! regulation of fatty acid beta-oxidation GO:0031998 6 6 0,000 6,394E-03 0,04287749 ! p53 binding GO:0002039 6 6 0,000 6,394E-03 0,04279881 ! demethylase activity GO:0032451 6 6 0,000 6,394E-03 0,04272043 ! positive regulation of nitric-oxide synthase activity GO:0051000 6 6 0,000 6,394E-03 0,04264233 ! regulation of platelet activation GO:0010543 7 6 0,000 6,394E-03 0,04256451 ! lipid phosphatase activity GO:0042577 7 6 0,000 6,394E-03 0,04248698 ! lens morphogenesis in camera-type eye GO:0002089 6 6 0,000 6,394E-03 0,04240973 ! guanylate cyclase activator activity GO:0030250 6 6 0,000 6,394E-03 0,04233276 GO:0010853|cyclase activator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 8 6 0,000 6,394E-03 0,04225607 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of exocytosis GO:0045921 6 6 0,000 6,394E-03 0,04217966 ! protein tyrosine kinase activator activity GO:0030296 8 6 0,000 6,394E-03 0,04210352 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 6,394E-03 0,04202766 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of steroid metabolic process GO:0045940 6 6 0,000 6,394E-03 0,04195207 ! LIM domain binding GO:0030274 7 6 0,000 6,394E-03 0,04187675 ! negative regulation of translational initiation GO:0045947 6 6 0,000 6,394E-03 0,04180171 ! positive regulation vascular endothelial growth factor production GO:0010575 6 6 0,000 6,394E-03 0,04172693 ! 5S class rRNA transcription GO:0042791 6 6 0,000 6,394E-03 0,04165241 GO:0042797|tRNA transcription from RNA polymerase III promoter, GO:0000127|transcription factor TFIIIC complex, ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 6,394E-03 0,04157817 ! axon guidance receptor activity GO:0008046 6 6 0,000 6,394E-03 0,04150419 ! zinc ion homeostasis GO:0055069 7 6 0,000 6,394E-03 0,04143047 ! positive regulation of gliogenesis GO:0014015 7 6 0,000 6,394E-03 0,04135701 GO:0045687|positive regulation of glial cell differentiation, ! centrosome duplication GO:0051298 7 6 0,000 6,394E-03 0,04128381 ! protein targeting to lysosome GO:0006622 6 6 0,000 6,394E-03 0,04121087 ! hyaluronan metabolic process GO:0030212 8 6 0,000 6,394E-03 0,04113819 ! protein retention in ER lumen GO:0006621 6 6 0,000 6,394E-03 0,04106576 ! ventricular cardiac muscle cell differentiation GO:0055012 8 6 0,000 6,394E-03 0,04099359 ! circadian sleep/wake cycle GO:0042745 7 6 0,000 6,394E-03 0,04092167 ! dynein binding GO:0045502 6 6 0,000 6,394E-03 0,04085 ! regulation of dendrite development GO:0050773 6 6 0,000 6,394E-03 0,04077859 ! peptidyl-arginine modification GO:0018195 6 6 0,000 6,394E-03 0,04070742 ! eating behavior GO:0042755 7 6 0,000 6,394E-03 0,0406365 ! protein localization to chromosome GO:0034502 8 6 0,000 6,394E-03 0,04056583 ! Hsp90 protein binding GO:0051879 7 6 0,000 6,394E-03 0,0404954 ! glycolipid binding GO:0051861 7 6 0,000 6,394E-03 0,04042522 ! MutLalpha complex binding GO:0032405 8 6 0,000 6,394E-03 0,04035528 ! mast cell activation GO:0045576 6 6 0,000 6,394E-03 0,04028558 ! regulation of focal adhesion formation GO:0051893 6 6 0,000 6,394E-03 0,04021612 ! nucleoside catabolic process GO:0009164 7 6 0,000 6,394E-03 0,04014691 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 6,394E-03 0,04007792 ! molybdopterin cofactor biosynthetic process GO:0032324 15 6 0,000 6,394E-03 0,04000918 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 6,394E-03 0,03994067 ! RNA polymerase II transcription elongation factor activity GO:0016944 6 6 0,000 6,394E-03 0,0398724 ! lipoxygenase activity GO:0016165 6 6 0,000 6,394E-03 0,03980436 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 6,394E-03 0,03973655 ! alpha DNA polymerase:primase complex GO:0005658 16 6 0,000 6,394E-03 0,03966897 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 6,394E-03 0,03960162 ! DNA replication factor C complex GO:0005663 7 6 0,000 6,394E-03 0,0395345 ! DNA replication factor A complex GO:0005662 7 6 0,000 6,394E-03 0,0394676 ! cilium morphogenesis GO:0060271 6 6 0,000 6,394E-03 0,03940093 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 6,394E-03 0,03933449 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 6,394E-03 0,03926827 ! chromatin assembly complex GO:0005678 16 6 0,000 6,394E-03 0,03920227 ! sex chromatin GO:0001739 6 6 0,000 6,394E-03 0,0391365 GO:0000803|sex chromosome, ! morphogenesis of a polarized epithelium GO:0001738 7 6 0,000 6,394E-03 0,03907094 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 7 6 0,000 6,394E-03 0,03900561 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! SAP kinase activity GO:0016909 7 6 0,000 6,394E-03 0,03894049 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 6,394E-03 0,03887559 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 7 6 0,000 6,394E-03 0,0388109 ! positive regulation of pseudopodium assembly GO:0031274 6 6 0,000 6,394E-03 0,03874643 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipoprotein metabolic process GO:0050746 7 6 0,000 6,394E-03 0,03868218 ! phosphatidylserine binding GO:0001786 6 6 0,000 6,394E-03 0,03861813 ! alpha-mannosidase activity GO:0004559 8 6 0,000 6,394E-03 0,0385543 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 6 0,000 6,394E-03 0,03849068 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 6,394E-03 0,03842727 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 11 6 0,000 6,394E-03 0,03836407 GO:0002820|negative regulation of adaptive immune response, ! myeloid dendritic cell activation GO:0001773 8 6 0,000 6,394E-03 0,03830107 GO:0043011|myeloid dendritic cell differentiation, ! immunological synapse GO:0001772 6 6 0,000 6,394E-03 0,03823828 ! leading edge membrane GO:0031256 8 6 0,000 6,394E-03 0,0381757 ! photoreceptor connecting cilium GO:0032391 7 6 0,000 6,394E-03 0,03811332 ! CARD domain binding GO:0050700 6 6 0,000 6,394E-03 0,03805115 ! regulation of muscle cell apoptosis GO:0010660 7 6 0,000 6,394E-03 0,03798917 ! COPII vesicle coat GO:0030127 7 6 0,000 6,394E-03 0,0379274 GO:0012507|ER to Golgi transport vesicle membrane, ! molybdenum ion binding GO:0030151 15 6 0,000 6,394E-03 0,03786583 ! glutathione biosynthetic process GO:0006750 7 6 0,000 6,394E-03 0,03780446 ! positive regulation of erythrocyte differentiation GO:0045648 8 6 0,000 6,394E-03 0,03774329 ! positive regulation of epidermis development GO:0045684 8 6 0,000 6,394E-03 0,03768231 ! proteasome regulator activity GO:0010860 6 6 0,000 6,394E-03 0,03762154 ! ceramidase activity GO:0017040 6 6 0,000 6,394E-03 0,03756095 ! antibiotic transport GO:0042891 7 6 0,000 6,394E-03 0,03750057 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 6,394E-03 0,03744037 ! regulation of T-helper cell differentiation GO:0045622 6 6 0,000 6,394E-03 0,03738037 ! sodium channel regulator activity GO:0017080 6 6 0,000 6,394E-03 0,03732056 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 6,394E-03 0,03726095 ! regulation of protein homodimerization activity GO:0043496 9 6 0,000 6,394E-03 0,03720152 ! response to fluid shear stress GO:0034405 6 6 0,000 6,394E-03 0,03714228 ! lymph node development GO:0048535 6 6 0,000 6,394E-03 0,03708323 ! negative regulation of viral reproduction GO:0048525 7 6 0,000 6,394E-03 0,03702437 ! triglyceride catabolic process GO:0019433 15 6 0,000 6,394E-03 0,03696569 ! positive regulation of fatty acid oxidation GO:0046321 6 6 0,000 6,394E-03 0,0369072 ! ectodermal gut morphogenesis GO:0048567 7 6 0,000 6,394E-03 0,0368489 GO:0007439|ectodermal gut development, ! T cell activation during immune response GO:0002286 6 6 0,000 6,394E-03 0,03679078 ! negative regulation of lipase activity GO:0060192 6 6 0,000 6,394E-03 0,03673284 ! activation of innate immune response GO:0002218 6 6 0,000 6,394E-03 0,03667508 GO:0002758|innate immune response-activating signal transduction, ! regulation of telomere maintenance via telomerase GO:0032210 7 6 0,000 6,394E-03 0,03661751 ! sarcoglycan complex GO:0016012 8 6 0,000 6,394E-03 0,03656011 ! natural killer cell mediated immunity GO:0002228 7 6 0,000 6,394E-03 0,0365029 GO:0042267|natural killer cell mediated cytotoxicity, ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 6 6 0,000 6,394E-03 0,03644586 ! neural plate development GO:0001840 7 6 0,000 6,394E-03 0,03638901 ! regulation of synaptic transmission, GABAergic GO:0032228 15 6 0,000 6,394E-03 0,03633232 ! catecholamine transport GO:0051937 6 6 0,000 6,394E-03 0,03627582 ! ether hydrolase activity GO:0016803 7 6 0,000 6,394E-03 0,03621949 ! FACIT collagen GO:0005593 6 6 0,000 6,394E-03 0,03616334 ! lactate dehydrogenase activity GO:0004457 6 6 0,000 6,394E-03 0,03610736 ! regulation of T cell receptor signaling pathway GO:0050856 7 6 0,000 6,394E-03 0,03605155 ! collagen type IV GO:0005587 6 6 0,000 6,394E-03 0,03599591 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 6,394E-03 0,03594045 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 7 6 0,000 6,394E-03 0,03588516 ! drug metabolic process GO:0017144 6 6 0,000 6,394E-03 0,03583003 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 6,394E-03 0,03577508 ! negative regulation of synaptic transmission GO:0050805 6 6 0,000 6,394E-03 0,03572029 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 6,394E-03 0,03566568 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 6,394E-03 0,03561122 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 6 6 0,000 6,394E-03 0,03555694 ! regulation of microtubule polymerization GO:0031113 6 6 0,000 6,394E-03 0,03550282 ! cellular anion homeostasis GO:0030002 6 6 0,000 6,394E-03 0,03544886 GO:0055081|anion homeostasis, ! regulation of MHC class II biosynthetic process GO:0045346 6 6 0,000 6,394E-03 0,03539507 ! negative regulation of protein ubiquitination GO:0031397 7 6 0,000 6,394E-03 0,03534144 ! negative regulation of fibroblast proliferation GO:0048147 6 6 0,000 6,394E-03 0,03528798 ! behavioral response to cocaine GO:0048148 9 6 0,000 6,394E-03 0,03523467 ! translation initiation factor binding GO:0031369 6 6 0,000 6,394E-03 0,03518153 ! nucleotide-sugar transport GO:0015780 6 6 0,000 6,394E-03 0,03512854 ! sulfur amino acid transmembrane transporter activity GO:0000099 6 6 0,000 6,394E-03 0,03507572 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 6,394E-03 0,03502305 ! quaternary ammonium group binding GO:0050997 7 6 0,000 6,394E-03 0,03497054 ! actin-dependent ATPase activity GO:0030898 7 6 0,000 6,394E-03 0,03491819 ! reproductive behavior GO:0019098 8 6 0,000 6,394E-03 0,034866 ! response to growth hormone stimulus GO:0060416 7 6 0,000 6,394E-03 0,03481396 GO:0060396|growth hormone receptor signaling pathway, ! negative regulation of JAK-STAT cascade GO:0046426 8 6 0,000 6,394E-03 0,03476207 ! nucleotide-excision repair, DNA incision GO:0033683 6 6 0,000 6,394E-03 0,03471035 ! negative regulation of cell-cell adhesion GO:0022408 8 6 0,000 6,394E-03 0,03465877 ! positive regulation of cell-cell adhesion GO:0022409 7 6 0,000 6,394E-03 0,03460735 ! induction of positive chemotaxis GO:0050930 7 6 0,000 6,394E-03 0,03455608 ! cohesin complex GO:0008278 6 6 0,000 6,394E-03 0,03450496 ! regulation of collagen biosynthetic process GO:0032965 7 6 0,000 6,394E-03 0,03445399 ! citrate metabolic process GO:0006101 7 6 0,000 6,394E-03 0,03440317 ! myelin sheath GO:0043209 8 6 0,000 6,394E-03 0,03435251 ! phototransduction, visible light GO:0007603 6 6 0,000 6,394E-03 0,03430199 ! opsonization GO:0008228 7 6 0,000 6,394E-03 0,03425162 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 6,394E-03 0,0342014 ! regulation of dopamine metabolic process GO:0042053 8 6 0,000 6,394E-03 0,03415132 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 7 6 0,000 6,394E-03 0,03410139 ! regulation of potassium ion transport GO:0043266 8 6 0,000 6,394E-03 0,03405161 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 6,394E-03 0,03400197 ! chemoattractant activity GO:0042056 6 6 0,000 6,394E-03 0,03395248 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 8 6 0,000 6,394E-03 0,03390313 ! low-density lipoprotein particle remodeling GO:0034374 6 6 0,000 6,394E-03 0,03385392 ! ornithine decarboxylase regulator activity GO:0042979 6 6 0,000 6,394E-03 0,03380486 ! leukocyte degranulation GO:0043299 6 6 0,000 6,394E-03 0,03375594 ! bile acid and bile salt transport GO:0015721 7 6 0,000 6,394E-03 0,03370716 ! regulation of cytokine-mediated signaling pathway GO:0001959 11 6 0,000 6,394E-03 0,03365852 ! mitochondrial genome maintenance GO:0000002 6 6 0,000 6,394E-03 0,03361002 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 6 0,000 6,394E-03 0,03356166 ! DNA topoisomerase activity GO:0003916 6 6 0,000 6,394E-03 0,03351344 ! protein geranylgeranyltransferase activity GO:0004661 7 6 0,000 6,394E-03 0,03346535 ! ceramide biosynthetic process GO:0046513 6 6 0,000 6,394E-03 0,03341741 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 6,394E-03 0,0333696 ! activin receptor activity GO:0017002 7 6 0,000 6,394E-03 0,03332193 ! astrocyte differentiation GO:0048708 6 6 0,000 6,394E-03 0,0332744 ! syncytium formation GO:0006949 6 6 0,000 6,394E-03 0,033227 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 6,394E-03 0,03317973 ! neutrophil activation GO:0042119 6 6 0,000 6,394E-03 0,0331326 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 6,394E-03 0,03308561 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 6,394E-03 0,03303874 ! positive regulation of activated T cell proliferation GO:0042104 7 6 0,000 6,394E-03 0,03299201 ! positive transcription elongation factor activity GO:0008159 7 6 0,000 6,394E-03 0,03294541 ! NuA4 histone acetyltransferase complex GO:0035267 8 6 0,000 6,394E-03 0,03289895 ! cellular polysaccharide catabolic process GO:0044247 17 6 0,000 6,394E-03 0,03285261 GO:0009251|glucan catabolic process, ! response to salt stress GO:0009651 7 6 0,000 6,394E-03 0,0328064 ! neuron apoptosis GO:0051402 7 6 0,000 6,394E-03 0,03276033 ! folic acid transport GO:0015884 8 6 0,000 6,394E-03 0,03271438 ! carnitine transport GO:0015879 6 6 0,000 6,394E-03 0,03266856 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 6,394E-03 0,03262287 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! parturition GO:0007567 7 6 0,000 6,394E-03 0,03257731 ! S-methyltransferase activity GO:0008172 6 6 0,000 6,394E-03 0,03253187 ! phospholipase D activity GO:0004630 6 6 0,000 6,394E-03 0,03248656 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 6,394E-03 0,03244138 ! intercalated disc GO:0014704 8 6 0,000 6,394E-03 0,03239632 ! G2/M transition checkpoint GO:0031576 24 6 0,000 6,394E-03 0,03235139 GO:0031572|G2/M transition DNA damage checkpoint, ! interaction with symbiont GO:0051702 6 6 0,000 6,394E-03 0,03230658 ! IgG binding GO:0019864 6 6 0,000 6,394E-03 0,0322619 ! regulation of T cell cytokine production GO:0002724 6 6 0,000 6,394E-03 0,03221734 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 6 6 0,000 6,394E-03 0,0321729 ! benzodiazepine receptor activity GO:0008503 7 6 0,000 6,394E-03 0,03212858 ! antigen processing and presentation of exogenous antigen GO:0019884 7 6 0,000 6,394E-03 0,03208439 ! regulation of T cell differentiation in the thymus GO:0033081 7 6 0,000 6,394E-03 0,03204032 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 6 6 0,000 6,394E-03 0,03199637 ! regulation of interleukin-4 production GO:0032673 6 6 0,000 6,394E-03 0,03195254 ! dendrite morphogenesis GO:0048813 7 6 0,000 6,394E-03 0,03190883 ! regulation of interleukin-1 production GO:0032652 7 6 0,000 6,394E-03 0,03186524 ! ribosomal large subunit biogenesis GO:0042273 7 6 0,000 6,394E-03 0,03182176 ! regulation of myeloid cell apoptosis GO:0033032 8 6 0,000 6,394E-03 0,03177841 ! nucleosome disassembly GO:0006337 7 6 0,000 6,394E-03 0,03173517 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! general transcriptional repressor activity GO:0016565 7 6 0,000 6,394E-03 0,03169205 ! regulation of mast cell activation GO:0033003 6 6 0,000 6,394E-03 0,03164905 ! tetracycline transporter activity GO:0008493 7 6 0,000 6,394E-03 0,03160617 GO:0042895|antibiotic transporter activity, ! guanylyltransferase activity GO:0070568 7 6 0,000 6,394E-03 0,0315634 ! receptor internalization GO:0031623 8 6 0,000 6,394E-03 0,03152075 ! N-formyl peptide receptor activity GO:0004982 6 6 0,000 6,394E-03 0,03147821 ! coenzyme A biosynthetic process GO:0015937 6 6 0,000 6,394E-03 0,03143578 ! histamine receptor activity GO:0004969 7 6 0,000 6,394E-03 0,03139348 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 6 0,000 6,394E-03 0,03135128 ! pyrimidine nucleotide sugar transmembrane transporter activity GO:0015165 6 6 0,000 6,394E-03 0,0313092 ! protein deubiquitination GO:0016579 6 6 0,000 6,394E-03 0,03126723 ! axonal fasciculation GO:0007413 7 6 0,000 6,394E-03 0,03122537 ! basic amino acid transmembrane transporter activity GO:0015174 6 6 0,000 6,394E-03 0,03118363 ! cytidine deaminase activity GO:0004126 6 6 0,000 6,394E-03 0,03114199 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 6,394E-03 0,03110047 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 6,394E-03 0,03105906 GO:0015991|ATP hydrolysis coupled proton transport, ! alpha-adrenergic receptor activity GO:0004936 9 6 0,000 6,394E-03 0,03101776 ! cytochrome-b5 reductase activity GO:0004128 7 6 0,000 6,394E-03 0,03097656 ! glycine binding GO:0016594 9 6 0,000 6,394E-03 0,03093548 ! apical protein localization GO:0045176 7 6 0,000 6,394E-03 0,03089451 ! ankyrin binding GO:0030506 6 6 0,000 6,394E-03 0,03085364 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 6,394E-03 0,03081288 ! thyroid hormone receptor activity GO:0004887 7 6 0,000 6,394E-03 0,03077223 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 6,394E-03 0,03073169 ! progesterone metabolic process GO:0042448 6 6 0,000 6,394E-03 0,03069125 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 7 6 0,000 6,394E-03 0,03065092 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 6,394E-03 0,0306107 ! type II transforming growth factor beta receptor binding GO:0005114 6 6 0,000 6,394E-03 0,03057058 ! ATP catabolic process GO:0006200 6 6 0,000 6,394E-03 0,03053057 ! CoA carboxylase activity GO:0016421 6 6 0,000 6,394E-03 0,03049066 ! determination of adult lifespan GO:0008340 6 6 0,000 6,394E-03 0,03045085 ! S-acyltransferase activity GO:0016417 6 6 0,000 6,394E-03 0,03041115 ! somatic stem cell maintenance GO:0035019 6 6 0,000 6,394E-03 0,03037155 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 6,394E-03 0,03033206 ! IkappaB kinase complex GO:0008385 7 6 0,000 6,394E-03 0,03029267 ! nucleobase transmembrane transporter activity GO:0015205 7 6 0,000 6,394E-03 0,03025338 ! store-operated calcium channel activity GO:0015279 6 6 0,000 6,394E-03 0,03021419 ! alkaline phosphatase activity GO:0004035 7 6 0,000 6,394E-03 0,0301751 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 6 0,000 6,394E-03 0,03013611 ! unconventional myosin complex GO:0016461 8 6 0,000 6,394E-03 0,03009723 ! tRNA transcription GO:0009304 7 7 0,000 7,456E-03 0,0350504 ! respiratory burst GO:0045730 7 7 0,000 7,456E-03 0,03500529 ! telencephalon cell migration GO:0022029 8 7 0,000 7,456E-03 0,0349603 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 7,456E-03 0,03491542 ! cation:chloride symporter activity GO:0015377 8 7 0,000 7,456E-03 0,03487065 ! RNA cap binding GO:0000339 8 7 0,000 7,456E-03 0,034826 ! generation of neurons in the forebrain GO:0021872 8 7 0,000 7,456E-03 0,03478147 ! ephrin receptor binding GO:0046875 9 7 0,000 7,456E-03 0,03473705 ! male meiosis I GO:0007141 7 7 0,000 7,456E-03 0,03469274 ! synapsis GO:0007129 7 7 0,000 7,456E-03 0,03464855 GO:0070192|chromosome organization involved in meiosis, ! insulin receptor substrate binding GO:0043560 10 7 0,000 7,456E-03 0,03460447 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 7,456E-03 0,03456049 ! type I transforming growth factor beta receptor binding GO:0034713 8 7 0,000 7,456E-03 0,03451664 ! signal peptide processing GO:0006465 7 7 0,000 7,456E-03 0,03447289 ! regulation of cardiac muscle cell proliferation GO:0060043 8 7 0,000 7,456E-03 0,03442925 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 7,456E-03 0,03438573 ! macrophage chemotaxis GO:0048246 7 7 0,000 7,456E-03 0,03434231 ! Golgi cisterna membrane GO:0032580 7 7 0,000 7,456E-03 0,034299 ! neurofilament cytoskeleton GO:0060053 8 7 0,000 7,456E-03 0,03425581 ! positive regulation of receptor-mediated endocytosis GO:0048260 7 7 0,000 7,456E-03 0,03421272 ! smoothened signaling pathway GO:0007224 8 7 0,000 7,456E-03 0,03416974 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 7,456E-03 0,03412686 ! oxidoreductase activity, oxidizing metal ions GO:0016722 7 7 0,000 7,456E-03 0,0340841 ! Arp2/3 protein complex GO:0005885 8 7 0,000 7,456E-03 0,03404144 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 7 7 0,000 7,456E-03 0,03399889 ! ATPase binding GO:0051117 8 7 0,000 7,456E-03 0,03395644 ! positive regulation of isotype switching GO:0045830 7 7 0,000 7,456E-03 0,0339141 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 7,456E-03 0,03387187 ! positive regulation of gene expression, epigenetic GO:0045815 7 7 0,000 7,456E-03 0,03382974 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 7 0,000 7,456E-03 0,03378771 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 7,456E-03 0,03374579 ! thymic T cell selection GO:0045061 16 7 0,000 7,456E-03 0,03370398 ! transepithelial chloride transport GO:0030321 7 7 0,000 7,456E-03 0,03366226 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 7,456E-03 0,03362065 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 7 7 0,000 7,456E-03 0,03357915 ! negative regulation of survival gene product expression GO:0008634 9 7 0,000 7,456E-03 0,03353774 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 7,456E-03 0,03349644 ! melanocyte differentiation GO:0030318 8 7 0,000 7,456E-03 0,03345524 ! malate dehydrogenase activity GO:0016615 8 7 0,000 7,456E-03 0,03341414 ! mitochondrial respiratory chain complex assembly GO:0033108 7 7 0,000 7,456E-03 0,03337314 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! DNA secondary structure binding GO:0000217 16 7 0,000 7,456E-03 0,03333224 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 8 7 0,000 7,456E-03 0,03329144 ! regulation of peptidyl-serine phosphorylation GO:0033135 7 7 0,000 7,456E-03 0,03325075 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 7,456E-03 0,03321015 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 7,456E-03 0,03316965 GO:0021940|positive regulation of granule cell precursor proliferation, ! V(D)J recombination GO:0033151 8 7 0,000 7,456E-03 0,03312924 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 7,456E-03 0,03308894 ! vascular endothelial growth factor receptor activity GO:0005021 12 7 0,000 7,456E-03 0,03304874 ! central nervous system neuron axonogenesis GO:0021955 8 7 0,000 7,456E-03 0,03300863 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 7,456E-03 0,03296862 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! response to tumor necrosis factor GO:0034612 8 7 0,000 7,456E-03 0,0329287 ! peptidoglycan metabolic process GO:0000270 9 7 0,000 7,456E-03 0,03288889 GO:0009253|peptidoglycan catabolic process, ! response to ATP GO:0033198 7 7 0,000 7,456E-03 0,03284917 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 8 7 0,000 7,456E-03 0,03280954 GO:0048500|signal recognition particle, ! stereocilium GO:0032420 10 7 0,000 7,456E-03 0,03277001 ! paraxial mesoderm morphogenesis GO:0048340 9 7 0,000 7,456E-03 0,03273058 ! melanosome organization GO:0032438 7 7 0,000 7,456E-03 0,03269124 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 8 7 0,000 7,456E-03 0,03265199 ! mesodermal cell differentiation GO:0048333 9 7 0,000 7,456E-03 0,03261284 GO:0001710|mesodermal cell fate commitment, ! positive regulation of neuroblast proliferation GO:0002052 7 7 0,000 7,456E-03 0,03257378 ! Rac protein signal transduction GO:0016601 7 7 0,000 7,456E-03 0,03253482 ! chondrocyte differentiation GO:0002062 7 7 0,000 7,456E-03 0,03249595 ! guanylate cyclase regulator activity GO:0030249 7 7 0,000 7,456E-03 0,03245717 GO:0010851|cyclase regulator activity, ! intestinal cholesterol absorption GO:0030299 9 7 0,000 7,456E-03 0,03241849 ! negative regulation of specific transcription from RNA polymerase II promoter GO:0010553 8 7 0,000 7,456E-03 0,03237989 ! determination of anterior/posterior axis, embryo GO:0008595 10 7 0,000 7,456E-03 0,03234139 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 8 7 0,000 7,456E-03 0,03230298 ! regulation of vascular endothelial growth factor production GO:0010574 7 7 0,000 7,456E-03 0,03226466 ! Schwann cell differentiation GO:0014037 8 7 0,000 7,456E-03 0,03222643 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 9 7 0,000 7,456E-03 0,0321883 ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 7,456E-03 0,03215025 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 7,456E-03 0,03211229 ! vinculin binding GO:0017166 9 7 0,000 7,456E-03 0,03207442 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 7,456E-03 0,03203664 ! regulation of collagen metabolic process GO:0010712 8 7 0,000 7,456E-03 0,03199895 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 7,456E-03 0,03196135 ! negative regulation of gliogenesis GO:0014014 8 7 0,000 7,456E-03 0,03192384 GO:0045686|negative regulation of glial cell differentiation, ! translation termination factor activity GO:0008079 7 7 0,000 7,456E-03 0,03188641 GO:0003747|translation release factor activity, ! purine base biosynthetic process GO:0009113 8 7 0,000 7,456E-03 0,03184907 ! cardiac muscle cell development GO:0055013 8 7 0,000 7,456E-03 0,03181182 ! fibrinolysis GO:0042730 9 7 0,000 7,456E-03 0,03177466 ! response to tropane GO:0014073 10 7 0,000 7,456E-03 0,03173758 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 7 7 0,000 7,456E-03 0,03170059 GO:0051904|pigment granule transport, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 8 7 0,000 7,456E-03 0,03166369 ! glycosylceramide metabolic process GO:0006677 7 7 0,000 7,456E-03 0,03162687 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 7 7 0,000 7,456E-03 0,03159014 ! laminin-1 complex GO:0005606 7 7 0,000 7,456E-03 0,03155349 GO:0043256|laminin complex, ! regulation of chondrocyte differentiation GO:0032330 8 7 0,000 7,456E-03 0,03151693 ! positive regulation of immunoglobulin mediated immune response GO:0002891 7 7 0,000 7,456E-03 0,03148045 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of lipid transport GO:0032370 8 7 0,000 7,456E-03 0,03144406 ! regulation of cell division GO:0051302 7 7 0,000 7,456E-03 0,03140775 ! holo TFIIH complex GO:0005675 7 7 0,000 7,456E-03 0,03137152 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 7 0,000 7,456E-03 0,03133538 ! chitinase activity GO:0004568 7 7 0,000 7,456E-03 0,03129932 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 8 7 0,000 7,456E-03 0,03126334 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! U12-type spliceosomal complex GO:0005689 8 7 0,000 7,456E-03 0,03122745 ! regulation of respiratory burst GO:0060263 8 7 0,000 7,456E-03 0,03119164 ! prophase GO:0051324 8 7 0,000 7,456E-03 0,03115591 ! peptidyl-histidine modification GO:0018202 8 7 0,000 7,456E-03 0,03112026 ! BBSome GO:0034464 7 7 0,000 7,456E-03 0,0310847 ! glycerophosphodiester phosphodiesterase activity GO:0008889 7 7 0,000 7,456E-03 0,03104921 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 7,456E-03 0,03101381 ! negative regulation of lymphocyte differentiation GO:0045620 8 7 0,000 7,456E-03 0,03097848 ! negative regulation of transmission of nerve impulse GO:0051970 7 7 0,000 7,456E-03 0,03094324 ! regulation of synaptic transmission, glutamatergic GO:0051966 8 7 0,000 7,456E-03 0,03090808 ! regulation of synaptogenesis GO:0051963 7 7 0,000 7,456E-03 0,030873 ! serine family amino acid catabolic process GO:0009071 7 7 0,000 7,456E-03 0,03083799 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 7,456E-03 0,03080307 ! glycolipid catabolic process GO:0019377 7 7 0,000 7,456E-03 0,03076822 GO:0046479|glycosphingolipid catabolic process, ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 8 7 0,000 7,456E-03 0,03073346 ! circadian behavior GO:0048512 9 7 0,000 7,456E-03 0,03069877 ! dorsal/ventral axis specification GO:0009950 7 7 0,000 7,456E-03 0,03066416 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 7 0,000 7,456E-03 0,03062963 ! striatum development GO:0021756 7 7 0,000 7,456E-03 0,03059517 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 8 7 0,000 7,456E-03 0,0305608 ! triglyceride biosynthetic process GO:0019432 7 7 0,000 7,456E-03 0,0305265 ! cerebellar Purkinje cell layer development GO:0021680 7 7 0,000 7,456E-03 0,03049228 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 7,456E-03 0,03045813 ! dystroglycan complex GO:0016011 9 7 0,000 7,456E-03 0,03042406 ! negative regulation of calcium ion transport GO:0051926 7 7 0,000 7,456E-03 0,03039007 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 7 0,000 7,456E-03 0,03035615 ! peroxiredoxin activity GO:0051920 7 7 0,000 7,456E-03 0,03032231 ! muscle adaptation GO:0043500 7 7 0,000 7,456E-03 0,03028854 ! regulation of muscle adaptation GO:0043502 7 7 0,000 7,456E-03 0,03025485 ! diacylglycerol metabolic process GO:0046339 7 7 0,000 7,456E-03 0,03022123 ! lysogeny GO:0030069 7 7 0,000 7,456E-03 0,03018769 GO:0019047|provirus integration, ! protein insertion into membrane GO:0051205 7 7 0,000 7,456E-03 0,03015422 ! sequestering of metal ion GO:0051238 9 7 0,000 7,456E-03 0,03012083 ! membrane attack complex GO:0005579 7 7 0,000 7,456E-03 0,03008751 ! metallo-sulfur cluster assembly GO:0031163 9 7 0,000 7,456E-03 0,03005426 GO:0016226|iron-sulfur cluster assembly, ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 7 0,000 7,456E-03 0,03002109 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 7 0,000 7,456E-03 0,02998799 ! GABA receptor binding GO:0050811 8 7 0,000 7,456E-03 0,02995497 ! sheet-forming collagen GO:0030935 7 7 0,000 7,456E-03 0,02992201 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 8 7 0,000 7,456E-03 0,02988913 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 8 7 0,000 7,456E-03 0,02985632 ! sphingomyelin phosphodiesterase activity GO:0004767 9 7 0,000 7,456E-03 0,02982359 ! regulation of epithelial cell differentiation GO:0030856 7 7 0,000 7,456E-03 0,02979092 ! 7S RNA binding GO:0008312 8 7 0,000 7,456E-03 0,02975833 ! positive regulation of lipid catabolic process GO:0050996 7 7 0,000 7,456E-03 0,0297258 ! protein phosphorylated amino acid binding GO:0045309 9 7 0,000 7,456E-03 0,02969335 ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 8 7 0,000 7,456E-03 0,02966097 ! regulation of long-term neuronal synaptic plasticity GO:0048169 17 7 0,000 7,456E-03 0,02962866 ! Golgi to endosome transport GO:0006895 8 7 0,000 7,456E-03 0,02959642 ! glucocorticoid receptor signaling pathway GO:0042921 7 7 0,000 7,456E-03 0,02956425 GO:0031958|corticosteroid receptor signaling pathway, ! succinate metabolic process GO:0006105 7 7 0,000 7,456E-03 0,02953215 ! fibril GO:0043205 7 7 0,000 7,456E-03 0,02950012 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 7,456E-03 0,02946816 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 7,456E-03 0,02943627 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 7 0,000 7,456E-03 0,02940444 ! sensory perception of bitter taste GO:0050913 7 7 0,000 7,456E-03 0,02937269 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 7,456E-03 0,029341 ! posttranscriptional gene silencing by RNA GO:0035194 9 7 0,000 7,456E-03 0,02930939 GO:0016441|posttranscriptional gene silencing, ! cell division site part GO:0032155 9 7 0,000 7,456E-03 0,02927784 GO:0032153|cell division site, ! laminin binding GO:0043236 7 7 0,000 7,456E-03 0,02924635 ! equilibrioception GO:0050957 10 7 0,000 7,456E-03 0,02921494 ! G-protein coupled receptor kinase activity GO:0004703 9 7 0,000 7,456E-03 0,02918359 ! titin binding GO:0031432 7 7 0,000 7,456E-03 0,02915231 ! chemosensory behavior GO:0007635 9 7 0,000 7,456E-03 0,0291211 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 7,456E-03 0,02908996 GO:0032107|regulation of response to nutrient levels, ! plasma lipoprotein particle assembly GO:0034377 7 7 0,000 7,456E-03 0,02905888 ! cobalamin binding GO:0031419 7 7 0,000 7,456E-03 0,02902787 ! sodium:phosphate symporter activity GO:0005436 8 7 0,000 7,456E-03 0,02899692 ! response to axon injury GO:0048678 9 7 0,000 7,456E-03 0,02896604 ! regulation of activin receptor signaling pathway GO:0032925 7 7 0,000 7,456E-03 0,02893522 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 7,456E-03 0,02890447 ! F-actin capping protein complex GO:0008290 8 7 0,000 7,456E-03 0,02887379 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 7,456E-03 0,02884317 ! cGMP-mediated signaling GO:0019934 8 7 0,000 7,456E-03 0,02881262 ! nerve growth factor receptor signaling pathway GO:0048011 8 7 0,000 7,456E-03 0,02878213 ! cAMP-dependent protein kinase activity GO:0004691 7 7 0,000 7,456E-03 0,0287517 ! senescence GO:0010149 8 7 0,000 7,456E-03 0,02872134 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 10 7 0,000 7,456E-03 0,02869104 ! nuclear localization sequence binding GO:0008139 8 7 0,000 7,456E-03 0,02866081 ! galactose metabolic process GO:0006012 8 7 0,000 7,456E-03 0,02863064 ! vesicle fusion GO:0006906 8 7 0,000 7,456E-03 0,02860054 ! maintenance of protein location in nucleus GO:0051457 7 7 0,000 7,456E-03 0,02857049 ! intracellular pH reduction GO:0051452 7 7 0,000 7,456E-03 0,02854051 ! glycerol ether catabolic process GO:0044269 16 7 0,000 7,456E-03 0,0285106 GO:0046461|neutral lipid catabolic process, GO:0046464|acylglycerol catabolic process, ! neurotransmitter catabolic process GO:0042135 9 7 0,000 7,456E-03 0,02848074 ! ruffle organization GO:0031529 9 7 0,000 7,456E-03 0,02845095 ! nucleoside transport GO:0015858 8 7 0,000 7,456E-03 0,02842122 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 7,456E-03 0,02839155 ! inclusion body GO:0016234 7 7 0,000 7,456E-03 0,02836195 ! Cajal body GO:0015030 7 7 0,000 7,456E-03 0,02833241 ! H4/H2A histone acetyltransferase complex GO:0043189 9 7 0,000 7,456E-03 0,02830292 ! rRNA modification GO:0000154 7 7 0,000 7,456E-03 0,0282735 ! PcG protein complex GO:0031519 7 7 0,000 7,456E-03 0,02824414 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 7,456E-03 0,02821484 ! NAD-dependent protein deacetylase activity GO:0034979 7 7 0,000 7,456E-03 0,02818561 GO:0017136|NAD-dependent histone deacetylase activity, ! apolipoprotein binding GO:0034185 9 7 0,000 7,456E-03 0,02815643 ! G1 DNA damage checkpoint GO:0031571 7 7 0,000 7,456E-03 0,02812731 ! segment specification GO:0007379 9 7 0,000 7,456E-03 0,02809825 ! pronucleus GO:0045120 25 7 0,000 7,456E-03 0,02806926 ! bile acid:sodium symporter activity GO:0008508 9 7 0,000 7,456E-03 0,02804032 ! Rac GTPase activator activity GO:0030675 9 7 0,000 7,456E-03 0,02801144 ! regulation of DNA repair GO:0006282 19 7 0,000 7,456E-03 0,02798262 ! preribosome GO:0030684 7 7 0,000 7,456E-03 0,02795386 ! DNA topological change GO:0006265 7 7 0,000 7,456E-03 0,02792516 ! DNA ligation GO:0006266 8 7 0,000 7,456E-03 0,02789652 ! hair follicle maturation GO:0048820 8 7 0,000 7,456E-03 0,02786794 ! renal water homeostasis GO:0003091 7 7 0,000 7,456E-03 0,02783942 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 7,456E-03 0,02781095 ! positive regulation of interleukin-6 production GO:0032755 7 7 0,000 7,456E-03 0,02778254 ! interleukin-1 receptor activity GO:0004908 8 7 0,000 7,456E-03 0,02775419 ! positive regulation of tumor necrosis factor production GO:0032760 7 7 0,000 7,456E-03 0,0277259 ! positive regulation of monooxygenase activity GO:0032770 7 7 0,000 7,456E-03 0,02769767 ! inositol trisphosphate 3-kinase activity GO:0008440 8 7 0,000 7,456E-03 0,02766949 ! phosphofructokinase activity GO:0008443 7 7 0,000 7,456E-03 0,02764137 ! gap junction channel activity GO:0005243 8 7 0,000 7,456E-03 0,02761331 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 10 7 0,000 7,456E-03 0,0275853 ! histone methylation GO:0016571 7 7 0,000 7,456E-03 0,02755736 ! positive regulation of interferon-gamma production GO:0032729 7 7 0,000 7,456E-03 0,02752946 ! negative regulation of tumor necrosis factor production GO:0032720 9 7 0,000 7,456E-03 0,02750163 ! mitochondrion morphogenesis GO:0070584 9 7 0,000 7,456E-03 0,02747385 ! muscle cell proliferation GO:0033002 8 7 0,000 7,456E-03 0,02744612 ! transcription termination GO:0006353 9 7 0,000 7,456E-03 0,02741846 ! regulation of transcription from RNA polymerase III promoter GO:0006359 16 7 0,000 7,456E-03 0,02739085 ! sodium:amino acid symporter activity GO:0005283 7 7 0,000 7,456E-03 0,02736329 ! cytidylyltransferase activity GO:0070567 8 7 0,000 7,456E-03 0,02733579 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 7,456E-03 0,02730834 ! ATP-dependent peptidase activity GO:0004176 7 7 0,000 7,456E-03 0,02728095 ! salivary gland development GO:0007431 7 7 0,000 7,456E-03 0,02725362 ! glucosidase activity GO:0015926 8 7 0,000 7,456E-03 0,02722634 ! NuRD complex GO:0016581 8 7 0,000 7,456E-03 0,02719911 ! negative regulation of nuclear division GO:0051784 7 7 0,000 7,456E-03 0,02717194 GO:0045839|negative regulation of mitosis, ! ATP-gated cation channel activity GO:0004931 9 7 0,000 7,456E-03 0,02714482 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 7 7 0,000 7,456E-03 0,02711776 ! response to redox state GO:0051775 8 7 0,000 7,456E-03 0,02709075 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 7,456E-03 0,02706379 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 7,456E-03 0,02703689 ! procollagen-proline dioxygenase activity GO:0019798 7 7 0,000 7,456E-03 0,02701004 ! actin monomer binding GO:0003785 7 7 0,000 7,456E-03 0,02698324 ! protein prenyltransferase activity GO:0008318 8 7 0,000 7,456E-03 0,0269565 ! endosome to lysosome transport GO:0008333 7 7 0,000 7,456E-03 0,02692981 ! regulation of Rac protein signal transduction GO:0035020 17 7 0,000 7,456E-03 0,02690317 ! germ cell migration GO:0008354 7 7 0,000 7,456E-03 0,02687659 ! fibroblast growth factor receptor binding GO:0005104 8 7 0,000 7,456E-03 0,02685006 ! negative regulation of organic acid transport GO:0032891 8 7 0,000 7,456E-03 0,02682358 ! CoA-ligase activity GO:0016405 8 7 0,000 7,456E-03 0,02679715 ! positive regulation of NF-kappaB import into nucleus GO:0042346 8 7 0,000 7,456E-03 0,02677078 ! interferon-alpha/beta receptor binding GO:0005132 7 7 0,000 7,456E-03 0,02674445 ! embryonic heart tube development GO:0035050 8 7 0,000 7,456E-03 0,02671818 ! dihydropyridine-sensitive calcium channel activity GO:0015270 10 7 0,000 7,456E-03 0,02669196 ! kainate selective glutamate receptor activity GO:0015277 8 7 0,000 7,456E-03 0,02666579 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 7,456E-03 0,02663968 ! amiloride-sensitive sodium channel activity GO:0015280 7 7 0,000 7,456E-03 0,02661361 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 7,456E-03 0,02658759 ! adenylate kinase activity GO:0004017 8 7 0,000 7,456E-03 0,02656163 ! negative regulation of immune effector process GO:0002698 13 7 0,000 7,456E-03 0,02653572 ! C-X-C chemokine receptor activity GO:0016494 7 7 0,000 7,456E-03 0,02650985 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 7 7 0,000 7,456E-03 0,02648404 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 10 8 0,000 8,517E-03 0,0302227 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 9 8 0,000 8,517E-03 0,03019333 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 8,517E-03 0,03016401 ! negative regulation of lipid biosynthetic process GO:0051055 18 8 0,000 8,517E-03 0,03013476 ! regulation of cellular amine metabolic process GO:0033238 10 8 0,000 8,517E-03 0,03010556 ! proteasome regulatory particle GO:0005838 8 8 0,000 8,517E-03 0,03007641 ! SMAD protein complex assembly GO:0007183 10 8 0,000 8,517E-03 0,03004732 ! regulation of smooth muscle cell migration GO:0014910 11 8 0,000 8,517E-03 0,03001829 ! protein self-association GO:0043621 8 8 0,000 8,517E-03 0,02998932 ! glycine hydroxymethyltransferase activity GO:0004372 9 8 0,000 8,517E-03 0,0299604 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 8 0,000 8,517E-03 0,02993154 ! neurotransmitter uptake GO:0001504 8 8 0,000 8,517E-03 0,02990273 ! regulation of activated T cell proliferation GO:0046006 9 8 0,000 8,517E-03 0,02987397 ! guanylate cyclase activity GO:0004383 9 8 0,000 8,517E-03 0,02984528 ! troponin complex GO:0005861 8 8 0,000 8,517E-03 0,02981663 ! eukaryotic translation initiation factor 3 complex GO:0005852 8 8 0,000 8,517E-03 0,02978805 ! tachykinin receptor signaling pathway GO:0007217 8 8 0,000 8,517E-03 0,02975951 ! keratinocyte proliferation GO:0043616 9 8 0,000 8,517E-03 0,02973104 ! negative regulation of muscle cell differentiation GO:0051148 10 8 0,000 8,517E-03 0,02970261 ! microtubule bundle formation GO:0001578 8 8 0,000 8,517E-03 0,02967424 ! middle ear morphogenesis GO:0042474 10 8 0,000 8,517E-03 0,02964593 ! ganglioside metabolic process GO:0001573 8 8 0,000 8,517E-03 0,02961767 ! regulation of mesenchymal cell proliferation GO:0010464 9 8 0,000 8,517E-03 0,02958946 GO:0002053|positive regulation of mesenchymal cell proliferation, ! ovulation from ovarian follicle GO:0001542 8 8 0,000 8,517E-03 0,02956131 ! ciliary or flagellar motility GO:0001539 8 8 0,000 8,517E-03 0,02953321 ! pathogenesis GO:0009405 8 8 0,000 8,517E-03 0,02950516 ! pH reduction GO:0045851 9 8 0,000 8,517E-03 0,02947717 ! small protein activating enzyme activity GO:0008641 10 8 0,000 8,517E-03 0,02944923 ! ribonucleoside triphosphate catabolic process GO:0009203 8 8 0,000 8,517E-03 0,02942134 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 8,517E-03 0,0293935 ! hemoglobin metabolic process GO:0020027 8 8 0,000 8,517E-03 0,02936572 ! regulation of S phase of mitotic cell cycle GO:0007090 8 8 0,000 8,517E-03 0,02933799 ! arginine catabolic process GO:0006527 9 8 0,000 8,517E-03 0,02931031 ! T-tubule GO:0030315 9 8 0,000 8,517E-03 0,02928269 ! regulation of defense response to virus by virus GO:0050690 17 8 0,000 8,517E-03 0,02925512 ! histidine catabolic process GO:0006548 8 8 0,000 8,517E-03 0,0292276 GO:0009077|histidine family amino acid catabolic process, ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 8,517E-03 0,02920013 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 8 0,000 8,517E-03 0,02917271 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 10 8 0,000 8,517E-03 0,02914534 ! proline metabolic process GO:0006560 10 8 0,000 8,517E-03 0,02911803 ! L-serine metabolic process GO:0006563 9 8 0,000 8,517E-03 0,02909076 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 8 8 0,000 8,517E-03 0,02906355 ! melanosome membrane GO:0033162 9 8 0,000 8,517E-03 0,02903639 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 8,517E-03 0,02900928 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 8 8 0,000 8,517E-03 0,02898221 ! pericentriolar material GO:0000242 9 8 0,000 8,517E-03 0,0289552 ! reverse cholesterol transport GO:0043691 8 8 0,000 8,517E-03 0,02892824 ! tumor necrosis factor receptor activity GO:0005031 8 8 0,000 8,517E-03 0,02890133 ! melanin metabolic process GO:0006582 10 8 0,000 8,517E-03 0,02887447 ! proton-transporting V-type ATPase, V1 domain GO:0033180 8 8 0,000 8,517E-03 0,02884766 ! phasic smooth muscle contraction GO:0014821 9 8 0,000 8,517E-03 0,0288209 ! Golgi lumen GO:0005796 8 8 0,000 8,517E-03 0,02879419 ! positive regulation of endothelial cell migration GO:0010595 9 8 0,000 8,517E-03 0,02876753 ! regulation of Cdc42 protein signal transduction GO:0032489 9 8 0,000 8,517E-03 0,02874092 GO:0043088|regulation of Cdc42 GTPase activity, ! methyltransferase complex GO:0034708 8 8 0,000 8,517E-03 0,02871436 GO:0035097|histone methyltransferase complex, ! paraxial mesoderm development GO:0048339 10 8 0,000 8,517E-03 0,02868784 ! stereocilium bundle GO:0032421 11 8 0,000 8,517E-03 0,02866138 ! forebrain cell migration GO:0021885 9 8 0,000 8,517E-03 0,02863496 ! peptidyl-threonine phosphorylation GO:0018107 11 8 0,000 8,517E-03 0,02860859 ! osteoblast development GO:0002076 11 8 0,000 8,517E-03 0,02858228 ! retinoic acid metabolic process GO:0042573 8 8 0,000 8,517E-03 0,02855601 ! retinol metabolic process GO:0042572 8 8 0,000 8,517E-03 0,02852978 ! negative regulation of muscle contraction GO:0045932 10 8 0,000 8,517E-03 0,02850361 ! structural constituent of epidermis GO:0030280 9 8 0,000 8,517E-03 0,02847748 ! clathrin binding GO:0030276 10 8 0,000 8,517E-03 0,0284514 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 9 8 0,000 8,517E-03 0,02842537 ! chondroitin sulfate biosynthetic process GO:0030206 9 8 0,000 8,517E-03 0,02839939 GO:0030204|chondroitin sulfate metabolic process, ! sodium:dicarboxylate symporter activity GO:0017153 9 8 0,000 8,517E-03 0,02837346 ! motor axon guidance GO:0008045 8 8 0,000 8,517E-03 0,02834757 ! protein targeting to vacuole GO:0006623 8 8 0,000 8,517E-03 0,02832173 ! negative regulation of axonogenesis GO:0050771 12 8 0,000 8,517E-03 0,02829593 ! peptidyl-asparagine modification GO:0018196 8 8 0,000 8,517E-03 0,02827019 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! melanosome localization GO:0032400 8 8 0,000 8,517E-03 0,02824449 GO:0032401|establishment of melanosome localization, GO:0051875|pigment granule localization, GO:0051905|establishment of pigment granule localization, ! mismatch repair complex binding GO:0032404 10 8 0,000 8,517E-03 0,02821883 ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 8,517E-03 0,02819322 ! protein-lipid complex assembly GO:0065005 8 8 0,000 8,517E-03 0,02816766 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 9 8 0,000 8,517E-03 0,02814215 ! phosphoinositide 3-kinase cascade GO:0014065 8 8 0,000 8,517E-03 0,02811668 ! regulation of dopamine secretion GO:0014059 9 8 0,000 8,517E-03 0,02809126 ! regulation of protein kinase B signaling cascade GO:0051896 9 8 0,000 8,517E-03 0,02806588 ! cranial nerve morphogenesis GO:0021602 9 8 0,000 8,517E-03 0,02804055 ! subpallium development GO:0021544 8 8 0,000 8,517E-03 0,02801527 ! positive regulation of Rho GTPase activity GO:0032321 11 8 0,000 8,517E-03 0,02799003 ! icosanoid secretion GO:0032309 10 8 0,000 8,517E-03 0,02796484 GO:0050482|arachidonic acid secretion, ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 8,517E-03 0,02793969 ! regulation of DNA replication initiation GO:0030174 8 8 0,000 8,517E-03 0,02791459 ! negative regulation of cytokine secretion GO:0050710 10 8 0,000 8,517E-03 0,02788953 ! dolichyl-diphosphooligosaccharide-protein glycotransferase activity GO:0004579 8 8 0,000 8,517E-03 0,02786451 ! exodeoxyribonuclease activity GO:0004529 18 8 0,000 8,517E-03 0,02783955 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! ER to Golgi transport vesicle GO:0030134 9 8 0,000 8,517E-03 0,02781462 ! nucleotide diphosphatase activity GO:0004551 9 8 0,000 8,517E-03 0,02778974 ! regulation of myoblast differentiation GO:0045661 9 8 0,000 8,517E-03 0,02776491 ! ubiquinone metabolic process GO:0006743 9 8 0,000 8,517E-03 0,02774012 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! neuromuscular process controlling posture GO:0050884 8 8 0,000 8,517E-03 0,02771537 ! multicellular organismal water homeostasis GO:0050891 8 8 0,000 8,517E-03 0,02769067 ! branched chain family amino acid catabolic process GO:0009083 9 8 0,000 8,517E-03 0,02766601 ! Wnt receptor activity GO:0042813 11 8 0,000 8,517E-03 0,0276414 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 8,517E-03 0,02761683 ! leukocyte mediated cytotoxicity GO:0001909 10 8 0,000 8,517E-03 0,0275923 ! detection of calcium ion GO:0005513 9 8 0,000 8,517E-03 0,02756782 ! negative regulation of glucose import GO:0046325 9 8 0,000 8,517E-03 0,02754338 ! blastocyst growth GO:0001832 8 8 0,000 8,517E-03 0,02751898 ! regulation of fibrinolysis GO:0051917 8 8 0,000 8,517E-03 0,02749463 ! negative regulation of telomere maintenance GO:0032205 9 8 0,000 8,517E-03 0,02747032 ! cerebellar cortex formation GO:0021697 9 8 0,000 8,517E-03 0,02744605 ! complement binding GO:0001848 11 8 0,000 8,517E-03 0,02742183 ! regulation of actin filament bundle formation GO:0032231 13 8 0,000 8,517E-03 0,02739765 GO:0051492|regulation of stress fiber formation, ! regulation of synaptic transmission, dopaminergic GO:0032225 10 8 0,000 8,517E-03 0,02737351 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 8 0,000 8,517E-03 0,02734941 ! amino sugar catabolic process GO:0046348 8 8 0,000 8,517E-03 0,02732536 GO:0006043|glucosamine catabolic process, ! FK506 binding GO:0005528 9 8 0,000 8,517E-03 0,02730135 GO:0005527|macrolide binding, ! dipeptidase activity GO:0016805 8 8 0,000 8,517E-03 0,02727738 ! positive regulation of amine transport GO:0051954 9 8 0,000 8,517E-03 0,02725345 ! release of sequestered calcium ion into cytosol GO:0051209 13 8 0,000 8,517E-03 0,02722956 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, ! B cell receptor signaling pathway GO:0050853 13 8 0,000 8,517E-03 0,02720572 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 8,517E-03 0,02718192 ! Golgi transport complex GO:0017119 8 8 0,000 8,517E-03 0,02715816 ! positive regulation of protein ubiquitination GO:0031398 17 8 0,000 8,517E-03 0,02713444 ! GDP binding GO:0019003 9 8 0,000 8,517E-03 0,02711076 ! positive regulation of glucose metabolic process GO:0010907 8 8 0,000 8,517E-03 0,02708713 ! prostate gland development GO:0030850 17 8 0,000 8,517E-03 0,02706353 ! DNA synthesis during DNA repair GO:0000731 19 8 0,000 8,517E-03 0,02703998 ! nitric-oxide synthase binding GO:0050998 9 8 0,000 8,517E-03 0,02701646 ! phosphate transport GO:0006817 9 8 0,000 8,517E-03 0,02699299 ! cellular copper ion homeostasis GO:0006878 8 8 0,000 8,517E-03 0,02696956 ! oligopeptide transport GO:0006857 8 8 0,000 8,517E-03 0,02694617 GO:0015198|oligopeptide transporter activity, ! pigment cell differentiation GO:0050931 9 8 0,000 8,517E-03 0,02692282 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 8,517E-03 0,02689951 ! oligosaccharyltransferase complex GO:0008250 8 8 0,000 8,517E-03 0,02687624 ! lipoprotein transport GO:0042953 9 8 0,000 8,517E-03 0,02685301 ! estrogen metabolic process GO:0008210 8 8 0,000 8,517E-03 0,02682982 ! nucleocytoplasmic transporter activity GO:0005487 8 8 0,000 8,517E-03 0,02680667 ! glucocorticoid metabolic process GO:0008211 8 8 0,000 8,517E-03 0,02678356 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 8 8 0,000 8,517E-03 0,02676049 ! T-helper 1 type immune response GO:0042088 8 8 0,000 8,517E-03 0,02673746 ! amyloid precursor protein catabolic process GO:0042987 10 8 0,000 8,517E-03 0,02671447 ! response to amphetamine GO:0001975 11 8 0,000 8,517E-03 0,02669152 ! mechanosensory behavior GO:0007638 8 8 0,000 8,517E-03 0,02666861 ! detection of chemical stimulus involved in sensory perception GO:0050907 8 8 0,000 8,517E-03 0,02664574 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 8,517E-03 0,02662291 ! C-X-C chemokine binding GO:0019958 8 8 0,000 8,517E-03 0,02660011 ! two-component signal transduction system (phosphorelay) GO:0000160 9 8 0,000 8,517E-03 0,02657736 ! glycerolipid catabolic process GO:0046503 17 8 0,000 8,517E-03 0,02655464 ! spinal cord dorsal/ventral patterning GO:0021513 10 8 0,000 8,517E-03 0,02653197 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 9 8 0,000 8,517E-03 0,02650933 ! inositol phosphate-mediated signaling GO:0048016 9 8 0,000 8,517E-03 0,02648673 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 8,517E-03 0,02646417 ! pigment granule organization GO:0048753 9 8 0,000 8,517E-03 0,02644165 ! GTP-dependent protein binding GO:0030742 11 8 0,000 8,517E-03 0,02641916 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 8,517E-03 0,02639672 ! regulation of interleukin-8 biosynthetic process GO:0045414 9 8 0,000 8,517E-03 0,02637431 ! regulation of pigmentation during development GO:0048070 11 8 0,000 8,517E-03 0,02635194 ! macrophage activation GO:0042116 8 8 0,000 8,517E-03 0,0263296 ! poly(A) RNA binding GO:0008143 8 8 0,000 8,517E-03 0,02630731 ! positive regulation of insulin secretion GO:0032024 10 8 0,000 8,517E-03 0,02628505 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 18 8 0,000 8,517E-03 0,02626283 ! asymmetric protein localization GO:0008105 9 8 0,000 8,517E-03 0,02624065 ! nucleotide-sugar transmembrane transporter activity GO:0005338 8 8 0,000 8,517E-03 0,02621851 ! neurotrophin binding GO:0043121 10 8 0,000 8,517E-03 0,0261964 ! nucleoside transmembrane transporter activity GO:0005337 9 8 0,000 8,517E-03 0,02617433 ! positive regulation of multicellular organismal metabolic process GO:0044253 9 8 0,000 8,517E-03 0,0261523 ! phagocytosis, engulfment GO:0006911 10 8 0,000 8,517E-03 0,02613031 ! UDP-glucosyltransferase activity GO:0035251 8 8 0,000 8,517E-03 0,02610835 ! neurotransmitter biosynthetic process GO:0042136 9 8 0,000 8,517E-03 0,02608643 ! UV protection GO:0009650 9 8 0,000 8,517E-03 0,02606454 ! peptidyl-proline dioxygenase activity GO:0031543 8 8 0,000 8,517E-03 0,02604269 ! eukaryotic translation initiation factor 4F complex GO:0016281 10 8 0,000 8,517E-03 0,02602088 ! glutathione peroxidase activity GO:0004602 17 8 0,000 8,517E-03 0,02599911 ! acyl-CoA thioesterase activity GO:0016291 10 8 0,000 8,517E-03 0,02597737 ! ATP-binding cassette (ABC) transporter complex GO:0043190 8 8 0,000 8,517E-03 0,02595567 ! ferric iron binding GO:0008199 9 8 0,000 8,517E-03 0,025934 ! response to UV-B GO:0010224 10 8 0,000 8,517E-03 0,02591237 ! intermediate filament organization GO:0045109 8 8 0,000 8,517E-03 0,02589078 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 8,517E-03 0,02586922 ! cellular extravasation GO:0045123 9 8 0,000 8,517E-03 0,0258477 ! skeletal muscle contraction GO:0003009 8 8 0,000 8,517E-03 0,02582621 ! positive regulation of cytokine production during immune response GO:0002720 8 8 0,000 8,517E-03 0,02580476 ! regulation of fatty acid biosynthetic process GO:0042304 17 8 0,000 8,517E-03 0,02578335 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 8,517E-03 0,02576197 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 8,517E-03 0,02574062 ! positive regulation of systemic arterial blood pressure GO:0003084 10 8 0,000 8,517E-03 0,02571932 ! negative regulation of systemic arterial blood pressure GO:0003085 9 8 0,000 8,517E-03 0,02569804 ! respiratory chain complex IV assembly GO:0008535 8 8 0,000 8,517E-03 0,0256768 ! erythrocyte development GO:0048821 9 8 0,000 8,517E-03 0,0256556 ! regulation of interleukin-10 production GO:0032653 8 8 0,000 8,517E-03 0,02563443 ! ribosome assembly GO:0042255 8 8 0,000 8,517E-03 0,0256133 ! postreplication repair GO:0006301 19 8 0,000 8,517E-03 0,0255922 ! gamma-tubulin binding GO:0043015 8 8 0,000 8,517E-03 0,02557114 ! NADPH oxidase complex GO:0043020 8 8 0,000 8,517E-03 0,02555011 ! mRNA cleavage GO:0006379 9 8 0,000 8,517E-03 0,02552912 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 9 8 0,000 8,517E-03 0,02550816 ! opioid receptor activity GO:0004985 8 8 0,000 8,517E-03 0,02548723 ! zymogen activation GO:0031638 9 8 0,000 8,517E-03 0,02546634 ! coenzyme A metabolic process GO:0015936 8 8 0,000 8,517E-03 0,02544548 ! cellular metabolic compound salvage GO:0043094 11 8 0,000 8,517E-03 0,02542466 ! costamere GO:0043034 8 8 0,000 8,517E-03 0,02540387 ! inositol trisphosphate kinase activity GO:0051766 9 8 0,000 8,517E-03 0,02538312 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 8,517E-03 0,02536239 ! sarcomere organization GO:0045214 9 8 0,000 8,517E-03 0,02534171 ! wide pore channel activity GO:0022829 9 8 0,000 8,517E-03 0,02532105 ! ligand-regulated transcription factor activity GO:0003706 10 8 0,000 8,517E-03 0,02530043 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 8,517E-03 0,02527985 ! hormone catabolic process GO:0042447 9 8 0,000 8,517E-03 0,0252593 ! mRNA 3'-UTR binding GO:0003730 9 8 0,000 8,517E-03 0,02523878 ! cGMP biosynthetic process GO:0006182 9 8 0,000 8,517E-03 0,02521829 ! lysozyme activity GO:0003796 10 8 0,000 8,517E-03 0,02519784 ! death receptor binding GO:0005123 8 8 0,000 8,517E-03 0,02517742 ! protein modification by small protein removal GO:0070646 9 8 0,000 8,517E-03 0,02515703 ! adult feeding behavior GO:0008343 9 8 0,000 8,517E-03 0,02513668 ! microtubule basal body GO:0005932 8 8 0,000 8,517E-03 0,02511636 ! pyrimidine nucleotide catabolic process GO:0006244 8 8 0,000 8,517E-03 0,02509607 ! interleukin-1 receptor binding GO:0005149 9 8 0,000 8,517E-03 0,02507581 ! calcium-release channel activity GO:0015278 8 8 0,000 8,517E-03 0,02505559 ! positive regulation of smooth muscle contraction GO:0045987 9 8 0,000 8,517E-03 0,0250354 ! behavioral response to nicotine GO:0035095 9 8 0,000 8,517E-03 0,02501524 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 8,517E-03 0,02499512 ! adenosine deaminase activity GO:0004000 8 8 0,000 8,517E-03 0,02497503 ! NAD biosynthetic process GO:0009435 9 8 0,000 8,517E-03 0,02495497 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 9 0,000 9,576E-03 0,02803758 ! positive regulation of glycogen biosynthetic process GO:0045725 9 9 0,000 9,576E-03 0,0280151 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 9,576E-03 0,02799265 ! sodium:hydrogen antiporter activity GO:0015385 9 9 0,000 9,576E-03 0,02797024 GO:0005451|monovalent cation:hydrogen antiporter activity, ! cGMP metabolic process GO:0046068 10 9 0,000 9,576E-03 0,02794786 ! myotube differentiation GO:0014902 9 9 0,000 9,576E-03 0,02792552 ! folic acid and derivative biosynthetic process GO:0009396 9 9 0,000 9,576E-03 0,02790322 ! N-glycan processing GO:0006491 10 9 0,000 9,576E-03 0,02788095 ! regulation of epidermal growth factor receptor activity GO:0007176 11 9 0,000 9,576E-03 0,02785871 ! actin-myosin filament sliding GO:0033275 11 9 0,000 9,576E-03 0,02783652 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! axon part GO:0033267 12 9 0,000 9,576E-03 0,02781435 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 10 9 0,000 9,576E-03 0,02779223 ! RNA methylation GO:0001510 9 9 0,000 9,576E-03 0,02777013 ! prostaglandin biosynthetic process GO:0001516 9 9 0,000 9,576E-03 0,02774808 GO:0046457|prostanoid biosynthetic process, ! negative regulation of gene-specific transcription GO:0032582 10 9 0,000 9,576E-03 0,02772605 ! artery development GO:0060840 9 9 0,000 9,576E-03 0,02770407 GO:0048844|artery morphogenesis, ! axonemal dynein complex GO:0005858 9 9 0,000 9,576E-03 0,02768211 ! regulation of postsynaptic membrane potential GO:0060078 11 9 0,000 9,576E-03 0,0276602 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 9 9 0,000 9,576E-03 0,02763831 ! auditory receptor cell differentiation GO:0042491 10 9 0,000 9,576E-03 0,02761647 ! positive regulation of heart contraction GO:0045823 11 9 0,000 9,576E-03 0,02759465 ! lipopolysaccharide binding GO:0001530 9 9 0,000 9,576E-03 0,02757287 ! regulated secretory pathway GO:0045055 10 9 0,000 9,576E-03 0,02755113 ! estrogen receptor binding GO:0030331 9 9 0,000 9,576E-03 0,02752942 ! inner mitochondrial membrane organization GO:0007007 10 9 0,000 9,576E-03 0,02750774 ! telomere maintenance via telomerase GO:0007004 20 9 0,000 9,576E-03 0,0274861 GO:0006278|RNA-dependent DNA replication, ! L-phenylalanine metabolic process GO:0006558 9 9 0,000 9,576E-03 0,02746449 GO:0006559|L-phenylalanine catabolic process, ! indolalkylamine metabolic process GO:0006586 9 9 0,000 9,576E-03 0,02744291 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 9 9 0,000 9,576E-03 0,02742137 ! urea metabolic process GO:0019627 19 9 0,000 9,576E-03 0,02739987 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! smooth endoplasmic reticulum GO:0005790 11 9 0,000 9,576E-03 0,02737839 ! autophagic vacuole GO:0005776 11 9 0,000 9,576E-03 0,02735695 ! Rac GTPase binding GO:0048365 10 9 0,000 9,576E-03 0,02733555 ! response to dietary excess GO:0002021 9 9 0,000 9,576E-03 0,02731417 ! regulation of sodium ion transport GO:0002028 10 9 0,000 9,576E-03 0,02729283 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 9,576E-03 0,02727153 ! lens development in camera-type eye GO:0002088 9 9 0,000 9,576E-03 0,02725026 ! male sex determination GO:0030238 9 9 0,000 9,576E-03 0,02722902 ! positive regulation of vasodilation GO:0045909 19 9 0,000 9,576E-03 0,02720781 ! positive regulation of muscle contraction GO:0045933 11 9 0,000 9,576E-03 0,02718664 ! regulation of smoothened signaling pathway GO:0008589 11 9 0,000 9,576E-03 0,0271655 ! male germ cell nucleus GO:0001673 11 9 0,000 9,576E-03 0,02714439 ! negative regulation of foam cell differentiation GO:0010745 12 9 0,000 9,576E-03 0,02712331 ! copper ion homeostasis GO:0055070 9 9 0,000 9,576E-03 0,02710227 ! protein heterooligomerization GO:0051291 10 9 0,000 9,576E-03 0,02708126 ! spectrin GO:0008091 9 9 0,000 9,576E-03 0,02706029 ! cardiac muscle cell differentiation GO:0055007 12 9 0,000 9,576E-03 0,02703934 ! purine nucleoside triphosphate catabolic process GO:0009146 9 9 0,000 9,576E-03 0,02701843 ! synaptic vesicle exocytosis GO:0016079 10 9 0,000 9,576E-03 0,02699755 ! regulation of B cell differentiation GO:0045577 10 9 0,000 9,576E-03 0,0269767 ! cell differentiation in hindbrain GO:0021533 10 9 0,000 9,576E-03 0,02695589 ! neural tube patterning GO:0021532 10 9 0,000 9,576E-03 0,0269351 ! fucose catabolic process GO:0019317 10 9 0,000 9,576E-03 0,02691435 GO:0042355|L-fucose catabolic process, ! retinal ganglion cell axon guidance GO:0031290 10 9 0,000 9,576E-03 0,02689363 ! regulation of hormone metabolic process GO:0032350 12 9 0,000 9,576E-03 0,02687294 ! sterol catabolic process GO:0016127 10 9 0,000 9,576E-03 0,02685229 GO:0006707|cholesterol catabolic process, ! oligosaccharyl transferase activity GO:0004576 9 9 0,000 9,576E-03 0,02683167 ! clathrin coat of coated pit GO:0030132 11 9 0,000 9,576E-03 0,02681107 ! SNARE complex GO:0031201 11 9 0,000 9,576E-03 0,02679051 ! negative regulation of osteoclast differentiation GO:0045671 10 9 0,000 9,576E-03 0,02676998 ! negative regulation of glucose transport GO:0010829 10 9 0,000 9,576E-03 0,02674949 ! methionine biosynthetic process GO:0009086 11 9 0,000 9,576E-03 0,02672902 ! peptidoglycan binding GO:0042834 9 9 0,000 9,576E-03 0,02670858 ! serine family amino acid biosynthetic process GO:0009070 10 9 0,000 9,576E-03 0,02668818 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 9,576E-03 0,02666781 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! nicotinamide nucleotide biosynthetic process GO:0019359 10 9 0,000 9,576E-03 0,02664747 ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 9 9 0,000 9,576E-03 0,02662716 GO:0003756|protein disulfide isomerase activity, ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 9,576E-03 0,02660688 ! beta-1,3-galactosyltransferase activity GO:0048531 10 9 0,000 9,576E-03 0,02658663 ! detection of bacterium GO:0016045 10 9 0,000 9,576E-03 0,02656641 ! lymphocyte activation during immune response GO:0002285 9 9 0,000 9,576E-03 0,02654622 ! embryonic gut development GO:0048566 10 9 0,000 9,576E-03 0,02652607 ! hydrolase activity, acting on ether bonds GO:0016801 10 9 0,000 9,576E-03 0,02650594 ! desmosome GO:0030057 10 9 0,000 9,576E-03 0,02648584 ! long-chain-fatty-acid-CoA ligase activity GO:0004467 9 9 0,000 9,576E-03 0,02646578 ! T cell receptor signaling pathway GO:0050852 14 9 0,000 9,576E-03 0,02644574 ! positive regulation of calcium-mediated signaling GO:0050850 11 9 0,000 9,576E-03 0,02642574 ! actin filament polymerization GO:0030041 10 9 0,000 9,576E-03 0,02640577 ! negative regulation of B cell activation GO:0050869 10 9 0,000 9,576E-03 0,02638582 ! establishment of cell polarity GO:0030010 10 9 0,000 9,576E-03 0,02636591 ! regulation of synapse organization GO:0050807 10 9 0,000 9,576E-03 0,02634602 ! septin complex GO:0031105 10 9 0,000 9,576E-03 0,02632617 GO:0032156|septin cytoskeleton, ! cholesterol transporter activity GO:0017127 9 9 0,000 9,576E-03 0,02630635 ! anchoring collagen GO:0030934 9 9 0,000 9,576E-03 0,02628655 ! defense response to Gram-negative bacterium GO:0050829 10 9 0,000 9,576E-03 0,02626679 ! regulation of developmental growth GO:0048638 11 9 0,000 9,576E-03 0,02624705 ! negative regulation of smooth muscle cell proliferation GO:0048662 10 9 0,000 9,576E-03 0,02622735 ! GMP binding GO:0019002 11 9 0,000 9,576E-03 0,02620767 GO:0030553|cGMP binding, ! photoreceptor activity GO:0009881 10 9 0,000 9,576E-03 0,02618803 ! virus-host interaction GO:0019048 13 9 0,000 9,576E-03 0,02616841 ! pentose-phosphate shunt GO:0006098 11 9 0,000 9,576E-03 0,02614882 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 9,576E-03 0,02612927 ! negative regulation of lipid catabolic process GO:0050995 11 9 0,000 9,576E-03 0,02610974 ! non-recombinational repair GO:0000726 10 9 0,000 9,576E-03 0,02609024 GO:0006303|double-strand break repair via nonhomologous end joining, ! cell volume homeostasis GO:0006884 10 9 0,000 9,576E-03 0,02607077 ! nuclear telomere cap complex GO:0000783 10 9 0,000 9,576E-03 0,02605133 GO:0000782|telomere cap complex, ! activin binding GO:0048185 10 9 0,000 9,576E-03 0,02603191 ! social behavior GO:0035176 10 9 0,000 9,576E-03 0,02601253 ! regulation of positive chemotaxis GO:0050926 11 9 0,000 9,576E-03 0,02599318 GO:0050927|positive regulation of positive chemotaxis, ! perikaryon GO:0043204 11 9 0,000 9,576E-03 0,02597385 ! nitric oxide biosynthetic process GO:0006809 10 9 0,000 9,576E-03 0,02595455 ! mating GO:0007618 11 9 0,000 9,576E-03 0,02593528 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 9 0,000 9,576E-03 0,02591604 ! rhythmic behavior GO:0007622 11 9 0,000 9,576E-03 0,02589683 ! phospholipid efflux GO:0033700 10 9 0,000 9,576E-03 0,02587765 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 9,576E-03 0,0258585 ! poly-purine tract binding GO:0070717 9 9 0,000 9,576E-03 0,02583937 ! T cell proliferation GO:0042098 10 9 0,000 9,576E-03 0,02582027 ! retinol dehydrogenase activity GO:0004745 9 9 0,000 9,576E-03 0,0258012 ! negative regulation of cell-matrix adhesion GO:0001953 10 9 0,000 9,576E-03 0,02578216 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 9 9 0,000 9,576E-03 0,02576315 ! interleukin-1 binding GO:0019966 10 9 0,000 9,576E-03 0,02574416 ! glucosyltransferase activity GO:0046527 9 9 0,000 9,576E-03 0,0257252 ! platelet-derived growth factor receptor signaling pathway GO:0048008 14 9 0,000 9,576E-03 0,02570628 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 11 9 0,000 9,576E-03 0,02568737 ! ovulation GO:0030728 9 9 0,000 9,576E-03 0,0256685 ! acid phosphatase activity GO:0003993 18 9 0,000 9,576E-03 0,02564965 ! embryonic cranial skeleton morphogenesis GO:0048701 10 9 0,000 9,576E-03 0,02563084 ! ER overload response GO:0006983 11 9 0,000 9,576E-03 0,02561204 ! B cell proliferation GO:0042100 10 9 0,000 9,576E-03 0,02559328 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 11 9 0,000 9,576E-03 0,02557454 ! calcium-transporting ATPase activity GO:0005388 11 9 0,000 9,576E-03 0,02555584 ! mannose metabolic process GO:0006013 13 9 0,000 9,576E-03 0,02553716 ! lipid digestion GO:0044241 11 9 0,000 9,576E-03 0,0255185 ! tumor necrosis factor binding GO:0043120 9 9 0,000 9,576E-03 0,02549987 ! tRNA methyltransferase activity GO:0008175 9 9 0,000 9,576E-03 0,02548128 ! regulation of bone resorption GO:0045124 10 9 0,000 9,576E-03 0,0254627 ! brain morphogenesis GO:0048854 9 9 0,000 9,576E-03 0,02544416 ! positive regulation of alpha-beta T cell differentiation GO:0046638 10 9 0,000 9,576E-03 0,02542564 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 10 9 0,000 9,576E-03 0,02540715 ! synaptic vesicle membrane GO:0030672 9 9 0,000 9,576E-03 0,02538868 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 9 0,000 9,576E-03 0,02537025 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9 9 0,000 9,576E-03 0,02535183 ! kinesin binding GO:0019894 9 9 0,000 9,576E-03 0,02533345 ! multicellular organismal aging GO:0010259 18 9 0,000 9,576E-03 0,02531509 ! Ran GTPase binding GO:0008536 11 9 0,000 9,576E-03 0,02529676 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 9,576E-03 0,02527846 ! protein import into peroxisome matrix GO:0016558 9 9 0,000 9,576E-03 0,02526018 ! mRNA polyadenylation GO:0006378 10 9 0,000 9,576E-03 0,02524193 ! neuropeptide Y receptor activity GO:0004983 10 9 0,000 9,576E-03 0,0252237 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 14 9 0,000 9,576E-03 0,0252055 ! prostaglandin receptor activity GO:0004955 11 9 0,000 9,576E-03 0,02518733 ! adrenoceptor activity GO:0004935 12 9 0,000 9,576E-03 0,02516918 ! regulation of isotype switching GO:0045191 9 9 0,000 9,576E-03 0,02515106 ! positive regulation of leukocyte migration GO:0002687 10 9 0,000 9,576E-03 0,02513297 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 10 9 0,000 9,576E-03 0,0251149 ! positive regulation of ATPase activity GO:0032781 11 9 0,000 9,576E-03 0,02509686 ! nonprotein amino acid metabolic process GO:0019794 19 9 0,000 9,576E-03 0,02507884 ! ionotropic glutamate receptor complex GO:0008328 14 9 0,000 9,576E-03 0,02506085 ! Notch binding GO:0005112 10 9 0,000 9,576E-03 0,02504289 ! ATPase regulator activity GO:0060590 10 9 0,000 9,576E-03 0,02502495 ! gamma-tubulin complex GO:0000930 19 9 0,000 9,576E-03 0,02500704 ! pyrimidine base metabolic process GO:0006206 10 9 0,000 9,576E-03 0,02498915 ! establishment or maintenance of apical/basal cell polarity GO:0035088 10 9 0,000 9,576E-03 0,02497129 ! tubulin-tyrosine ligase activity GO:0004835 10 9 0,000 9,576E-03 0,02495345 ! alcohol dehydrogenase (NAD) activity GO:0004022 10 9 0,000 9,576E-03 0,02493564 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 12 10 0,000 0,01063509 0,02767247 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 12 10 0,000 0,01063509 0,02765274 ! oligosaccharide biosynthetic process GO:0009312 10 10 0,000 0,01063509 0,02763305 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 10 0,000 0,01063509 0,02761338 ! sleep GO:0030431 11 10 0,000 0,01063509 0,02759374 ! positive regulation of lipid biosynthetic process GO:0046889 10 10 0,000 0,01063509 0,02757413 ! lipid particle GO:0005811 10 10 0,000 0,01063509 0,02755454 ! filopodium assembly GO:0046847 14 10 0,000 0,01063509 0,02753499 ! UTP metabolic process GO:0046051 12 10 0,000 0,01063509 0,02751546 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 13 10 0,000 0,01063509 0,02749596 ! guanylate kinase activity GO:0004385 14 10 0,000 0,01063509 0,02747649 ! integral to mitochondrial membrane GO:0032592 10 10 0,000 0,01063509 0,02745704 ! COPI coating of Golgi vesicle GO:0048205 11 10 0,000 0,01063509 0,02743762 GO:0048200|Golgi transport vesicle coating, ! platelet alpha granule membrane GO:0031092 11 10 0,000 0,01063509 0,02741823 ! macromolecule transmembrane transporter activity GO:0022884 11 10 0,000 0,01063509 0,02739887 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 10 0,000 0,01063509 0,02737953 ! thyroid hormone receptor coactivator activity GO:0030375 11 10 0,000 0,01063509 0,02736022 GO:0010861|thyroid hormone receptor activator activity, ! regulation of receptor activity GO:0010469 12 10 0,000 0,01063509 0,02734094 ! lung alveolus development GO:0048286 11 10 0,000 0,01063509 0,02732169 ! regulation of chemokine biosynthetic process GO:0045073 11 10 0,000 0,01063509 0,02730246 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01063509 0,02728326 ! negative regulation of striated muscle development GO:0045843 11 10 0,000 0,01063509 0,02726409 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 0,01063509 0,02724494 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 11 10 0,000 0,01063509 0,02722582 ! regulation of mRNA processing GO:0050684 12 10 0,000 0,01063509 0,02720673 ! positive regulation of survival gene product expression GO:0045885 12 10 0,000 0,01063509 0,02718766 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 11 10 0,000 0,01063509 0,02716863 ! transforming growth factor beta binding GO:0050431 11 10 0,000 0,01063509 0,02714961 ! histidine metabolic process GO:0006547 10 10 0,000 0,01063509 0,02713063 GO:0009075|histidine family amino acid metabolic process, ! glucan biosynthetic process GO:0009250 10 10 0,000 0,01063509 0,02711167 GO:0005978|glycogen biosynthetic process, ! endosome organization GO:0007032 13 10 0,000 0,01063509 0,02709274 ! death receptor activity GO:0005035 11 10 0,000 0,01063509 0,02707383 ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 0,01063509 0,02705495 ! entry into host cell GO:0030260 11 10 0,000 0,01063509 0,0270361 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 10 10 0,000 0,01063509 0,02701727 ! filamentous actin GO:0031941 11 10 0,000 0,01063509 0,02699847 ! behavioral fear response GO:0001662 12 10 0,000 0,01063509 0,02697969 GO:0002209|behavioral defense response, ! bone mineralization GO:0030282 12 10 0,000 0,01063509 0,02696094 ! negative regulation of ossification GO:0030279 12 10 0,000 0,01063509 0,02694222 ! phosphatidylcholine biosynthetic process GO:0006656 11 10 0,000 0,01063509 0,02692352 ! macrophage differentiation GO:0030225 11 10 0,000 0,01063509 0,02690485 ! positive regulation of phagocytosis GO:0050766 11 10 0,000 0,01063509 0,02688621 ! recycling endosome membrane GO:0055038 11 10 0,000 0,01063509 0,02686759 ! regulation of fat cell differentiation GO:0045598 11 10 0,000 0,01063509 0,02684899 ! snRNA metabolic process GO:0016073 10 10 0,000 0,01063509 0,02683043 GO:0016180|snRNA processing, ! glycosphingolipid biosynthetic process GO:0006688 11 10 0,000 0,01063509 0,02681188 ! regulation of mitochondrial membrane potential GO:0051881 11 10 0,000 0,01063509 0,02679337 ! purine ribonucleotide catabolic process GO:0009154 10 10 0,000 0,01063509 0,02677488 ! positive regulation of Ras GTPase activity GO:0032320 14 10 0,000 0,01063509 0,02675641 ! immunoglobulin production during immune response GO:0002381 10 10 0,000 0,01063509 0,02673797 ! nitric oxide metabolic process GO:0046209 20 10 0,000 0,01063509 0,02671956 ! induction of an organ GO:0001759 12 10 0,000 0,01063509 0,02670117 ! response to estradiol stimulus GO:0032355 11 10 0,000 0,01063509 0,0266828 ! synaptic vesicle endocytosis GO:0048488 12 10 0,000 0,01063509 0,02666447 ! negative regulation of MAPKKK cascade GO:0043409 12 10 0,000 0,01063509 0,02664615 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 10 0,000 0,01063509 0,02662786 ! MHC class II receptor activity GO:0032395 14 10 0,000 0,01063509 0,0266096 ! peptidyl-lysine modification GO:0018205 11 10 0,000 0,01063509 0,02659136 ! ribonuclease P activity GO:0004526 10 10 0,000 0,01063509 0,02657315 ! COPI vesicle coat GO:0030126 12 10 0,000 0,01063509 0,02655496 GO:0030663|COPI coated vesicle membrane, ! telomere maintenance via telomere lengthening GO:0010833 21 10 0,000 0,01063509 0,0265368 ! vitamin transporter activity GO:0051183 12 10 0,000 0,01063509 0,02651866 ! snRNA binding GO:0017069 11 10 0,000 0,01063509 0,02650054 ! negative regulation of osteoblast differentiation GO:0045668 12 10 0,000 0,01063509 0,02648246 ! heparan sulfate sulfotransferase activity GO:0034483 10 10 0,000 0,01063509 0,02646439 ! fatty-acid ligase activity GO:0015645 10 10 0,000 0,01063509 0,02644635 ! intramolecular transferase activity, phosphotransferases GO:0016868 11 10 0,000 0,01063509 0,02642834 ! quaternary ammonium group transport GO:0015697 10 10 0,000 0,01063509 0,02641035 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 10 10 0,000 0,01063509 0,02639238 ! metalloenzyme inhibitor activity GO:0048551 11 10 0,000 0,01063509 0,02637444 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! anterior/posterior axis specification GO:0009948 14 10 0,000 0,01063509 0,02635652 ! regulation of RNA splicing GO:0043484 13 10 0,000 0,01063509 0,02633863 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 10 10 0,000 0,01063509 0,02632076 ! trophectodermal cell differentiation GO:0001829 11 10 0,000 0,01063509 0,02630291 ! positive regulation of neuron apoptosis GO:0043525 11 10 0,000 0,01063509 0,02628509 ! extracellular matrix binding GO:0050840 11 10 0,000 0,01063509 0,0262673 ! regulation of synapse structure and activity GO:0050803 11 10 0,000 0,01063509 0,02624952 ! autophagic vacuole formation GO:0000045 11 10 0,000 0,01063509 0,02623178 ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 0,01063509 0,02621405 ! negative regulation of cell projection organization GO:0031345 14 10 0,000 0,01063509 0,02619635 ! negative regulation of cellular catabolic process GO:0031330 11 10 0,000 0,01063509 0,02617868 ! rough endoplasmic reticulum membrane GO:0030867 10 10 0,000 0,01063509 0,02616102 ! thyroid gland development GO:0030878 12 10 0,000 0,01063509 0,02614339 ! DNA bending activity GO:0008301 11 10 0,000 0,01063509 0,02612579 ! regulation of phosphatase activity GO:0010921 10 10 0,000 0,01063509 0,02610821 ! neutral lipid biosynthetic process GO:0046460 10 10 0,000 0,01063509 0,02609065 GO:0046463|acylglycerol biosynthetic process, ! embryonic hindlimb morphogenesis GO:0035116 11 10 0,000 0,01063509 0,02607312 ! embryonic forelimb morphogenesis GO:0035115 12 10 0,000 0,01063509 0,02605561 ! regulation of glucan biosynthetic process GO:0010962 10 10 0,000 0,01063509 0,02603812 GO:0005979|regulation of glycogen biosynthetic process, GO:0032885|regulation of polysaccharide biosynthetic process, ! secondary active sulfate transmembrane transporter activity GO:0008271 11 10 0,000 0,01063509 0,02602066 ! regulation of glycolysis GO:0006110 11 10 0,000 0,01063509 0,02600322 ! nucleotidase activity GO:0008252 10 10 0,000 0,01063509 0,0259858 ! phosphatidylinositol phosphate kinase activity GO:0016307 11 10 0,000 0,01063509 0,02596841 ! dipeptidyl-peptidase activity GO:0008239 12 10 0,000 0,01063509 0,02595104 ! androgen metabolic process GO:0008209 11 10 0,000 0,01063509 0,02593369 ! lateral plasma membrane GO:0016328 13 10 0,000 0,01063509 0,02591636 ! MAP kinase kinase activity GO:0004708 12 10 0,000 0,01063509 0,02589906 ! cation:amino acid symporter activity GO:0005416 12 10 0,000 0,01063509 0,02588179 ! startle response GO:0001964 13 10 0,000 0,01063509 0,02586453 ! amyloid precursor protein metabolic process GO:0042982 12 10 0,000 0,01063509 0,0258473 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 12 10 0,000 0,01063509 0,02583009 ! positive regulation of endothelial cell proliferation GO:0001938 13 10 0,000 0,01063509 0,02581291 ! 3'-5'-exoribonuclease activity GO:0000175 10 10 0,000 0,01063509 0,02579574 ! spinal cord patterning GO:0021511 12 10 0,000 0,01063509 0,0257786 ! peptide or protein amino-terminal blocking GO:0018409 11 10 0,000 0,01063509 0,02576149 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 10 10 0,000 0,01063509 0,02574439 GO:0033549|MAP kinase phosphatase activity, ! response to X-ray GO:0010165 11 10 0,000 0,01063509 0,02572732 ! embryonic eye morphogenesis GO:0048048 14 10 0,000 0,01063509 0,02571027 ! sodium:potassium-exchanging ATPase activity GO:0005391 12 10 0,000 0,01063509 0,02569324 ! zinc ion transmembrane transporter activity GO:0005385 13 10 0,000 0,01063509 0,02567624 ! positive regulation of glycogen metabolic process GO:0070875 11 10 0,000 0,01063509 0,02565926 ! glucose transmembrane transporter activity GO:0005355 10 10 0,000 0,01063509 0,0256423 ! regulation of intracellular pH GO:0051453 10 10 0,000 0,01063509 0,02562536 ! retrograde transport, endosome to Golgi GO:0042147 12 10 0,000 0,01063509 0,02560845 ! regulation of multicellular organismal metabolic process GO:0044246 11 10 0,000 0,01063509 0,02559155 ! adult heart development GO:0007512 14 10 0,000 0,01063509 0,02557469 ! neuromuscular junction development GO:0007528 12 10 0,000 0,01063509 0,02555784 ! carbohydrate phosphatase activity GO:0019203 11 10 0,000 0,01063509 0,02554101 ! O-methyltransferase activity GO:0008171 10 10 0,000 0,01063509 0,02552421 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 10 10 0,000 0,01063509 0,02550743 ! signalosome GO:0008180 10 10 0,000 0,01063509 0,02549067 ! lysophospholipase activity GO:0004622 19 10 0,000 0,01063509 0,02547393 ! prefoldin complex GO:0016272 10 10 0,000 0,01063509 0,02545722 ! alpha-beta T cell differentiation GO:0046632 12 10 0,000 0,01063509 0,02544052 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 10 0,000 0,01063509 0,02542385 ! positive regulation of T cell mediated immunity GO:0002711 10 10 0,000 0,01063509 0,0254072 ! nucleoside bisphosphate metabolic process GO:0033865 10 10 0,000 0,01063509 0,02539057 ! endocytic vesicle membrane GO:0030666 10 10 0,000 0,01063509 0,02537397 ! gland morphogenesis GO:0022612 11 10 0,000 0,01063509 0,02535738 ! icosanoid receptor activity GO:0004953 13 10 0,000 0,01063509 0,02534082 GO:0004954|prostanoid receptor activity, ! regulation of macrophage activation GO:0043030 11 10 0,000 0,01063509 0,02532428 ! peptide transporter activity GO:0015197 10 10 0,000 0,01063509 0,02530776 ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 10 10 0,000 0,01063509 0,02529126 ! regulation of leukocyte migration GO:0002685 11 10 0,000 0,01063509 0,02527479 ! muscle maintenance GO:0046716 10 10 0,000 0,01063509 0,02525833 ! acid secretion GO:0046717 12 10 0,000 0,01063509 0,0252419 ! retinoid-X receptor activity GO:0004886 11 10 0,000 0,01063509 0,02522549 ! catecholamine biosynthetic process GO:0042423 11 10 0,000 0,01063509 0,0252091 ! thyroid hormone metabolic process GO:0042403 11 10 0,000 0,01063509 0,02519273 ! GTPase inhibitor activity GO:0005095 21 10 0,000 0,01063509 0,02517638 ! somatic recombination of immunoglobulin gene segments GO:0016447 10 10 0,000 0,01063509 0,02516005 ! pattern recognition receptor activity GO:0008329 10 10 0,000 0,01063509 0,02514374 ! quinone cofactor metabolic process GO:0042375 11 10 0,000 0,01063509 0,02512746 ! regulation of organic acid transport GO:0032890 12 10 0,000 0,01063509 0,0251112 ! platelet-derived growth factor receptor binding GO:0005161 14 10 0,000 0,01063509 0,02509495 ! C-acyltransferase activity GO:0016408 12 10 0,000 0,01063509 0,02507873 ! cAMP-dependent protein kinase complex GO:0005952 12 10 0,000 0,01063509 0,02506253 ! water channel activity GO:0015250 15 10 0,000 0,01063509 0,02504635 ! phospholipase inhibitor activity GO:0004859 10 10 0,000 0,01063509 0,02503019 ! regulation of embryonic development GO:0045995 12 10 0,000 0,01063509 0,02501405 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 10 10 0,000 0,01063509 0,02499794 ! acrosome reaction GO:0007340 12 10 0,000 0,01063509 0,02498184 ! mitochondrion localization GO:0051646 10 10 0,000 0,01063509 0,02496576 ! cilium part GO:0044441 10 10 0,000 0,01063509 0,02494971 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 12 11 0,000 0,01169267 0,02741314 ! 'de novo' posttranslational protein folding GO:0051084 11 11 0,000 0,01169267 0,02739553 ! negative regulation of blood pressure GO:0045776 13 11 0,000 0,01169267 0,02737795 ! cadmium ion binding GO:0046870 15 11 0,000 0,01169267 0,02736039 ! hemoglobin complex GO:0005833 13 11 0,000 0,01169267 0,02734285 ! CTP metabolic process GO:0046036 13 11 0,000 0,01169267 0,02732533 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0009148|pyrimidine nucleoside triphosphate biosynthetic process, ! regulation of neurotransmitter secretion GO:0046928 12 11 0,000 0,01169267 0,02730784 ! response to pain GO:0048265 12 11 0,000 0,01169267 0,02729037 ! regulation of viral genome replication GO:0045069 13 11 0,000 0,01169267 0,02727292 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 11 11 0,000 0,01169267 0,02725549 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 12 11 0,000 0,01169267 0,02723809 ! nucleotide-sugar metabolic process GO:0009225 13 11 0,000 0,01169267 0,0272207 ! regulation of catecholamine secretion GO:0050433 12 11 0,000 0,01169267 0,02720334 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 0,01169267 0,02718601 ! peptide antigen binding GO:0042605 14 11 0,000 0,01169267 0,02716869 ! polyamine metabolic process GO:0006595 11 11 0,000 0,01169267 0,0271514 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 13 11 0,000 0,01169267 0,02713413 GO:0045125|bioactive lipid receptor activity, ! nucleobase biosynthetic process GO:0046112 13 11 0,000 0,01169267 0,02711688 ! regulation of calcium ion transport into cytosol GO:0010522 15 11 0,000 0,01169267 0,02709965 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 12 11 0,000 0,01169267 0,02708244 GO:0002717|positive regulation of natural killer cell mediated immunity, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 12 11 0,000 0,01169267 0,02706526 ! protein homotetramerization GO:0051289 13 11 0,000 0,01169267 0,02704809 ! regulation of gliogenesis GO:0014013 13 11 0,000 0,01169267 0,02703095 GO:0045685|regulation of glial cell differentiation, ! oligodendrocyte development GO:0014003 11 11 0,000 0,01169267 0,02701383 ! cytoskeletal adaptor activity GO:0008093 17 11 0,000 0,01169267 0,02699674 ! regulation of circadian rhythm GO:0042752 11 11 0,000 0,01169267 0,02697966 ! low-density lipoprotein receptor binding GO:0050750 11 11 0,000 0,01169267 0,02696261 ! response to dsRNA GO:0043331 21 11 0,000 0,01169267 0,02694557 ! response to amine stimulus GO:0014075 15 11 0,000 0,01169267 0,02692856 GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 14 11 0,000 0,01169267 0,02691157 ! sphingomyelin metabolic process GO:0006684 13 11 0,000 0,01169267 0,02689461 ! cell wall macromolecule catabolic process GO:0016998 14 11 0,000 0,01169267 0,02687766 ! spinal cord motor neuron differentiation GO:0021522 12 11 0,000 0,01169267 0,02686073 ! retinal binding GO:0016918 11 11 0,000 0,01169267 0,02684383 ! leukocyte activation during immune response GO:0002366 11 11 0,000 0,01169267 0,02682695 GO:0002263|cell activation during immune response, ! regulation of sterol transport GO:0032371 12 11 0,000 0,01169267 0,02681008 GO:0032374|regulation of cholesterol transport, ! beta-tubulin binding GO:0048487 14 11 0,000 0,01169267 0,02679324 ! autonomic nervous system development GO:0048483 12 11 0,000 0,01169267 0,02677642 ! negative regulation of lipid transport GO:0032369 12 11 0,000 0,01169267 0,02675963 ! photoreceptor outer segment GO:0001750 12 11 0,000 0,01169267 0,02674285 ! positive regulation of interleukin-1 secretion GO:0050716 12 11 0,000 0,01169267 0,02672609 ! peptidyl-threonine modification GO:0018210 15 11 0,000 0,01169267 0,02670936 ! clathrin coat of trans-Golgi network vesicle GO:0030130 15 11 0,000 0,01169267 0,02669264 ! regulation of interleukin-1 beta secretion GO:0050706 12 11 0,000 0,01169267 0,02667595 ! regulation of epidermis development GO:0045682 14 11 0,000 0,01169267 0,02665928 ! positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 11 11 0,000 0,01169267 0,02664263 ! midbrain development GO:0030901 12 11 0,000 0,01169267 0,026626 ! musculoskeletal movement GO:0050881 12 11 0,000 0,01169267 0,02660939 GO:0050879|multicellular organismal movement, ! histone deacetylase binding GO:0042826 11 11 0,000 0,01169267 0,0265928 ! regulation of RNA stability GO:0043487 13 11 0,000 0,01169267 0,02657623 GO:0043488|regulation of mRNA stability, ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 11 11 0,000 0,01169267 0,02655968 ! cell killing GO:0001906 13 11 0,000 0,01169267 0,02654315 ! regulation of cellular carbohydrate catabolic process GO:0043471 13 11 0,000 0,01169267 0,02652664 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 12 11 0,000 0,01169267 0,02651016 ! carbon-sulfur lyase activity GO:0016846 11 11 0,000 0,01169267 0,02649369 ! cerebellar cortex morphogenesis GO:0021696 13 11 0,000 0,01169267 0,02647725 ! regulation of blood vessel endothelial cell migration GO:0043535 13 11 0,000 0,01169267 0,02646082 ! folic acid binding GO:0005542 12 11 0,000 0,01169267 0,02644442 ! mRNA 3'-end processing GO:0031124 12 11 0,000 0,01169267 0,02642803 ! regulation of calcium-mediated signaling GO:0050848 13 11 0,000 0,01169267 0,02641167 ! positive regulation of protein polymerization GO:0032273 11 11 0,000 0,01169267 0,02639532 ! microspike assembly GO:0030035 15 11 0,000 0,01169267 0,026379 ! lamellipodium assembly GO:0030032 22 11 0,000 0,01169267 0,0263627 ! fibrillar collagen GO:0005583 12 11 0,000 0,01169267 0,02634641 ! inner ear receptor cell differentiation GO:0060113 12 11 0,000 0,01169267 0,02633015 ! cytoplasmic sequestering of protein GO:0051220 12 11 0,000 0,01169267 0,02631391 ! negative regulation of muscle development GO:0048635 13 11 0,000 0,01169267 0,02629768 ! very-long-chain fatty acid metabolic process GO:0000038 12 11 0,000 0,01169267 0,02628148 ! synaptonemal complex GO:0000795 11 11 0,000 0,01169267 0,0262653 ! reproductive cellular process GO:0048610 13 11 0,000 0,01169267 0,02624914 ! cortical actin cytoskeleton organization GO:0030866 12 11 0,000 0,01169267 0,02623299 ! positive regulation of B cell proliferation GO:0030890 15 11 0,000 0,01169267 0,02621687 ! Golgi vesicle budding GO:0048194 12 11 0,000 0,01169267 0,02620076 ! response to cAMP GO:0051591 11 11 0,000 0,01169267 0,02618468 ! detection of mechanical stimulus GO:0050982 13 11 0,000 0,01169267 0,02616862 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 13 11 0,000 0,01169267 0,02615257 ! regulation of cell projection assembly GO:0060491 11 11 0,000 0,01169267 0,02613655 ! negative regulation of transcription factor import into nucleus GO:0042992 11 11 0,000 0,01169267 0,02612054 ! positive regulation of transcription factor import into nucleus GO:0042993 13 11 0,000 0,01169267 0,02610456 ! macromolecular complex remodeling GO:0034367 11 11 0,000 0,01169267 0,02608859 GO:0034368|protein-lipid complex remodeling, GO:0034369|plasma lipoprotein particle remodeling, ! protein serine/threonine/tyrosine kinase activity GO:0004712 13 11 0,000 0,01169267 0,02607264 ! glycerol ether biosynthetic process GO:0046504 11 11 0,000 0,01169267 0,02605672 ! drug transport GO:0015893 12 11 0,000 0,01169267 0,02604081 ! FMN binding GO:0010181 12 11 0,000 0,01169267 0,02602492 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 11 0,000 0,01169267 0,02600905 ! water transporter activity GO:0005372 17 11 0,000 0,01169267 0,0259932 ! regulation of glycogen metabolic process GO:0070873 12 11 0,000 0,01169267 0,02597737 GO:0032881|regulation of polysaccharide metabolic process, ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01169267 0,02596156 ! multicellular organism growth GO:0035264 12 11 0,000 0,01169267 0,02594577 ! integrator complex GO:0032039 11 11 0,000 0,01169267 0,02593 ! L-glutamate transmembrane transporter activity GO:0005313 13 11 0,000 0,01169267 0,02591424 GO:0015172|acidic amino acid transmembrane transporter activity, ! DNA integration GO:0015074 11 11 0,000 0,01169267 0,02589851 ! brush border membrane GO:0031526 12 11 0,000 0,01169267 0,02588279 ! actin cytoskeleton reorganization GO:0031532 14 11 0,000 0,01169267 0,0258671 ! macroautophagy GO:0016236 12 11 0,000 0,01169267 0,02585142 ! protein disulfide oxidoreductase activity GO:0015035 11 11 0,000 0,01169267 0,02583576 ! neuromuscular junction GO:0031594 12 11 0,000 0,01169267 0,02582012 ! positive regulation of peptide secretion GO:0002793 13 11 0,000 0,01169267 0,0258045 ! positive regulation of alpha-beta T cell activation GO:0046635 12 11 0,000 0,01169267 0,0257889 ! organic anion transmembrane transporter activity GO:0008514 11 11 0,000 0,01169267 0,02577332 ! response to antibiotic GO:0046677 13 11 0,000 0,01169267 0,02575776 ! protein-hormone receptor activity GO:0016500 12 11 0,000 0,01169267 0,02574221 ! bile acid transmembrane transporter activity GO:0015125 13 11 0,000 0,01169267 0,02572669 ! proteasome accessory complex GO:0022624 11 11 0,000 0,01169267 0,02571118 ! neuroblast proliferation GO:0007405 13 11 0,000 0,01169267 0,02569569 ! non-G-protein coupled 7TM receptor activity GO:0004926 14 11 0,000 0,01169267 0,02568022 ! negative regulation of neurological system process GO:0031645 13 11 0,000 0,01169267 0,02566477 ! nitric oxide mediated signal transduction GO:0007263 12 11 0,000 0,01169267 0,02564934 ! protein kinase C binding GO:0005080 11 11 0,000 0,01169267 0,02563392 ! transforming growth factor beta receptor, cytoplasmic mediator activity GO:0005072 12 11 0,000 0,01169267 0,02561853 ! male genitalia development GO:0030539 15 11 0,000 0,01169267 0,02560315 ! receptor inhibitor activity GO:0030547 12 11 0,000 0,01169267 0,02558779 GO:0048019|receptor antagonist activity, ! estrogen receptor signaling pathway GO:0030520 12 11 0,000 0,01169267 0,02557245 ! L-fucose metabolic process GO:0042354 13 11 0,000 0,01169267 0,02555713 ! palmitoyltransferase activity GO:0016409 11 11 0,000 0,01169267 0,02554182 ! arylsulfatase activity GO:0004065 12 11 0,000 0,01169267 0,02552654 ! sterol transporter activity GO:0015248 11 11 0,000 0,01169267 0,02551127 ! response to nicotine GO:0035094 13 11 0,000 0,01169267 0,02549602 ! adenylate cyclase activity GO:0004016 11 11 0,000 0,01169267 0,02548079 ! rRNA transcription GO:0009303 12 12 0,000 0,01274917 0,02776655 ! ER-associated protein catabolic process GO:0030433 14 12 0,000 0,01274917 0,02774998 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of blood pressure GO:0045777 15 12 0,000 0,01274917 0,02773344 ! superoxide anion generation GO:0042554 12 12 0,000 0,01274917 0,02771691 ! pteridine and derivative biosynthetic process GO:0042559 22 12 0,000 0,01274917 0,0277004 ! regulation of S phase GO:0033261 16 12 0,000 0,01274917 0,02768391 ! regulation of chemokine production GO:0032642 13 12 0,000 0,01274917 0,02766744 ! male meiosis GO:0007140 12 12 0,000 0,01274917 0,027651 ! signal complex assembly GO:0007172 15 12 0,000 0,01274917 0,02763457 ! positive regulation of GTPase activity GO:0043547 17 12 0,000 0,01274917 0,02761816 ! GTP metabolic process GO:0046039 14 12 0,000 0,01274917 0,02760176 ! retina morphogenesis in camera-type eye GO:0060042 16 12 0,000 0,01274917 0,02758539 ! hair follicle morphogenesis GO:0031069 14 12 0,000 0,01274917 0,02756904 ! voltage-gated sodium channel complex GO:0001518 15 12 0,000 0,01274917 0,02755271 GO:0034706|sodium channel complex, ! RNA polyadenylation GO:0043631 13 12 0,000 0,01274917 0,0275364 ! cartilage condensation GO:0001502 14 12 0,000 0,01274917 0,0275201 ! polysome GO:0005844 14 12 0,000 0,01274917 0,02750383 ! hippocampus development GO:0021766 13 12 0,000 0,01274917 0,02748757 ! lipoprotein receptor binding GO:0070325 13 12 0,000 0,01274917 0,02747134 ! beta-amyloid binding GO:0001540 12 12 0,000 0,01274917 0,02745512 ! negative regulation of endocytosis GO:0045806 15 12 0,000 0,01274917 0,02743892 ! regulation of interferon-gamma biosynthetic process GO:0045072 15 12 0,000 0,01274917 0,02742274 ! chylomicron GO:0042627 13 12 0,000 0,01274917 0,02740658 ! T cell selection GO:0045058 22 12 0,000 0,01274917 0,02739044 ! negative regulation of proteolysis GO:0045861 12 12 0,000 0,01274917 0,02737432 ! glycolipid biosynthetic process GO:0009247 13 12 0,000 0,01274917 0,02735822 ! WW domain binding GO:0050699 12 12 0,000 0,01274917 0,02734214 ! methionine metabolic process GO:0006555 14 12 0,000 0,01274917 0,02732607 ! nuclear heterochromatin GO:0005720 12 12 0,000 0,01274917 0,02731003 ! glycine metabolic process GO:0006544 14 12 0,000 0,01274917 0,027294 ! plasma membrane organization GO:0007009 12 12 0,000 0,01274917 0,02727799 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01274917 0,027262 ! ribonucleotide catabolic process GO:0009261 12 12 0,000 0,01274917 0,02724603 ! Golgi organization GO:0007030 15 12 0,000 0,01274917 0,02723008 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 0,01274917 0,02721414 ! mitotic spindle organization GO:0007052 13 12 0,000 0,01274917 0,02719823 ! integral to peroxisomal membrane GO:0005779 12 12 0,000 0,01274917 0,02718233 ! integral to membrane of membrane fraction GO:0000299 13 12 0,000 0,01274917 0,02716646 ! regulation of the force of heart contraction GO:0002026 13 12 0,000 0,01274917 0,0271506 ! temperature homeostasis GO:0001659 13 12 0,000 0,01274917 0,02713476 ! negative regulation of mitotic cell cycle GO:0045930 15 12 0,000 0,01274917 0,02711894 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 0,01274917 0,02710313 ! lipoprotein receptor activity GO:0030228 12 12 0,000 0,01274917 0,02708735 ! cotranslational protein targeting to membrane GO:0006613 14 12 0,000 0,01274917 0,02707158 ! axon cargo transport GO:0008088 13 12 0,000 0,01274917 0,02705583 ! regulation of phagocytosis GO:0050764 14 12 0,000 0,01274917 0,0270401 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 12 0,000 0,01274917 0,02702439 ! nucleoside triphosphate catabolic process GO:0009143 12 12 0,000 0,01274917 0,0270087 ! transcription elongation factor complex GO:0008023 12 12 0,000 0,01274917 0,02699302 ! basal lamina GO:0005605 12 12 0,000 0,01274917 0,02697736 ! regulation of interleukin-1 secretion GO:0050704 13 12 0,000 0,01274917 0,02696172 ! pancreatic ribonuclease activity GO:0004522 12 12 0,000 0,01274917 0,0269461 ! tRNA-specific ribonuclease activity GO:0004549 12 12 0,000 0,01274917 0,0269305 ! biomineral formation GO:0031214 14 12 0,000 0,01274917 0,02691492 ! water homeostasis GO:0030104 12 12 0,000 0,01274917 0,02689935 ! promoter binding GO:0010843 14 12 0,000 0,01274917 0,0268838 ! regulation of erythrocyte differentiation GO:0045646 15 12 0,000 0,01274917 0,02686827 ! intestinal absorption GO:0050892 14 12 0,000 0,01274917 0,02685276 ! pseudouridine synthase activity GO:0009982 12 12 0,000 0,01274917 0,02683726 ! oocyte differentiation GO:0009994 13 12 0,000 0,01274917 0,02682178 ! oxygen transport GO:0015671 13 12 0,000 0,01274917 0,02680632 GO:0005344|oxygen transporter activity, ! thymus development GO:0048538 13 12 0,000 0,01274917 0,02679088 ! cholesterol efflux GO:0033344 13 12 0,000 0,01274917 0,02677546 ! digestive tract morphogenesis GO:0048546 14 12 0,000 0,01274917 0,02676005 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! racemase and epimerase activity GO:0016854 13 12 0,000 0,01274917 0,02674467 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 14 12 0,000 0,01274917 0,0267293 ! tropomyosin binding GO:0005523 12 12 0,000 0,01274917 0,02671394 ! blastocyst formation GO:0001825 13 12 0,000 0,01274917 0,02669861 ! regulation of telomere maintenance GO:0032204 16 12 0,000 0,01274917 0,02668329 ! internal side of plasma membrane GO:0009898 16 12 0,000 0,01274917 0,02666799 ! mannose binding GO:0005537 13 12 0,000 0,01274917 0,02665271 ! phosphoprotein binding GO:0051219 14 12 0,000 0,01274917 0,02663744 ! defense response to fungus GO:0050832 12 12 0,000 0,01274917 0,02662219 ! embryonic placenta development GO:0001892 16 12 0,000 0,01274917 0,02660696 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 0,01274917 0,02659175 ! cell wall macromolecule metabolic process GO:0044036 15 12 0,000 0,01274917 0,02657656 ! acyl-CoA binding GO:0000062 12 12 0,000 0,01274917 0,02656138 ! cortical cytoskeleton organization GO:0030865 13 12 0,000 0,01274917 0,02654622 ! regulation of nitric-oxide synthase activity GO:0050999 12 12 0,000 0,01274917 0,02653107 ! copper ion transport GO:0006825 12 12 0,000 0,01274917 0,02651595 ! calcium ion transport into cytosol GO:0060402 19 12 0,000 0,01274917 0,02650084 ! inositol metabolic process GO:0006020 21 12 0,000 0,01274917 0,02648575 ! vesicle targeting, to, from or within Golgi GO:0048199 13 12 0,000 0,01274917 0,02647067 ! forelimb morphogenesis GO:0035136 15 12 0,000 0,01274917 0,02645562 ! protein complex disassembly GO:0043241 15 12 0,000 0,01274917 0,02644058 GO:0043624|cellular protein complex disassembly, ! ion channel inhibitor activity GO:0008200 15 12 0,000 0,01274917 0,02642555 GO:0016248|channel inhibitor activity, ! low-density lipoprotein particle GO:0034362 13 12 0,000 0,01274917 0,02641055 ! lipoprotein particle clearance GO:0034381 14 12 0,000 0,01274917 0,02639556 ! receptor signaling protein tyrosine kinase activity GO:0004716 14 12 0,000 0,01274917 0,02638059 ! endothelial cell differentiation GO:0045446 15 12 0,000 0,01274917 0,02636563 ! exosome (RNase complex) GO:0000178 13 12 0,000 0,01274917 0,02635069 ! DNA N-glycosylase activity GO:0019104 12 12 0,000 0,01274917 0,02633577 ! endoderm development GO:0007492 13 12 0,000 0,01274917 0,02632087 ! positive regulation of Ras protein signal transduction GO:0046579 25 12 0,000 0,01274917 0,02630598 ! focal adhesion formation GO:0048041 16 12 0,000 0,01274917 0,02629111 ! T cell receptor complex GO:0042101 31 12 0,000 0,01274917 0,02627626 ! cellular carbohydrate catabolic process GO:0044275 25 12 0,000 0,01274917 0,02626142 ! dicarboxylic acid transmembrane transporter activity GO:0005310 14 12 0,000 0,01274917 0,0262466 ! CoA hydrolase activity GO:0016289 14 12 0,000 0,01274917 0,0262318 ! histone acetyltransferase complex GO:0000123 14 12 0,000 0,01274917 0,02621701 ! regulation of alpha-beta T cell differentiation GO:0046637 13 12 0,000 0,01274917 0,02620224 ! alpha-beta T cell activation GO:0046631 14 12 0,000 0,01274917 0,02618749 ! retinol binding GO:0019841 12 12 0,000 0,01274917 0,02617275 ! regulation of organ growth GO:0046620 12 12 0,000 0,01274917 0,02615803 ! regulation of natural killer cell mediated immunity GO:0002715 13 12 0,000 0,01274917 0,02614332 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! vasoconstriction GO:0042310 13 12 0,000 0,01274917 0,02612864 ! histone acetylation GO:0016573 13 12 0,000 0,01274917 0,02611397 ! ribosome binding GO:0043022 13 12 0,000 0,01274917 0,02609931 ! delayed rectifier potassium channel activity GO:0005251 14 12 0,000 0,01274917 0,02608467 ! organic cation transmembrane transporter activity GO:0015101 12 12 0,000 0,01274917 0,02607005 ! phosphate transmembrane transporter activity GO:0015114 14 12 0,000 0,01274917 0,02605545 ! tissue regeneration GO:0042246 12 12 0,000 0,01274917 0,02604086 ! sulfate transmembrane transporter activity GO:0015116 13 12 0,000 0,01274917 0,02602629 ! adenylyltransferase activity GO:0070566 13 12 0,000 0,01274917 0,02601173 ! germ cell nucleus GO:0043073 14 12 0,000 0,01274917 0,02599719 ! trans-Golgi network transport vesicle membrane GO:0012510 16 12 0,000 0,01274917 0,02598267 ! hexose transmembrane transporter activity GO:0015149 12 12 0,000 0,01274917 0,02596816 ! hexosaminidase activity GO:0015929 12 12 0,000 0,01274917 0,02595367 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 0,01274917 0,02593919 ! activation of NF-kappaB-inducing kinase activity GO:0007250 14 12 0,000 0,01274917 0,02592473 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 13 12 0,000 0,01274917 0,02591029 ! dopamine metabolic process GO:0042417 15 12 0,000 0,01274917 0,02589587 ! somatic diversification of immunoglobulins GO:0016445 12 12 0,000 0,01274917 0,02588145 ! phosphoinositide 3-kinase activity GO:0035004 14 12 0,000 0,01274917 0,02586706 ! insulin-like growth factor receptor binding GO:0005159 14 12 0,000 0,01274917 0,02585268 ! bacterial binding GO:0008367 14 12 0,000 0,01274917 0,02583832 ! steroid hydroxylase activity GO:0008395 12 12 0,000 0,01274917 0,02582397 ! cardiac cell differentiation GO:0035051 16 12 0,000 0,01274917 0,02580964 ! phosphoinositide 3-kinase complex GO:0005942 14 12 0,000 0,01274917 0,02579533 ! localization within membrane GO:0051668 13 12 0,000 0,01274917 0,02578103 ! microtubule-based flagellum GO:0009434 12 12 0,000 0,01274917 0,02576674 ! axoneme part GO:0044447 12 12 0,000 0,01274917 0,02575248 ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,0138046 0,02786895 ! neuron maturation GO:0042551 14 13 0,000 0,0138046 0,02785353 ! positive regulation of small GTPase mediated signal transduction GO:0051057 26 13 0,000 0,0138046 0,02783814 ! negative regulation of bone remodeling GO:0046851 15 13 0,000 0,0138046 0,02782276 ! bone remodeling GO:0046849 14 13 0,000 0,0138046 0,02780739 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,0138046 0,02779205 ! regulation of receptor-mediated endocytosis GO:0048259 15 13 0,000 0,0138046 0,02777672 ! striated muscle thin filament GO:0005865 14 13 0,000 0,0138046 0,02776141 ! patterning of blood vessels GO:0001569 15 13 0,000 0,0138046 0,02774611 ! organelle fusion GO:0048284 16 13 0,000 0,0138046 0,02773083 ! palate development GO:0060021 15 13 0,000 0,0138046 0,02771557 ! induction of apoptosis via death domain receptors GO:0008625 16 13 0,000 0,0138046 0,02770032 ! arginine metabolic process GO:0006525 14 13 0,000 0,0138046 0,0276851 ! ER-Golgi intermediate compartment membrane GO:0033116 23 13 0,000 0,0138046 0,02766988 ! tyrosine metabolic process GO:0006570 15 13 0,000 0,0138046 0,02765469 ! response to retinoic acid GO:0032526 17 13 0,000 0,0138046 0,02763951 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 15 13 0,000 0,0138046 0,02762435 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lipase inhibitor activity GO:0055102 14 13 0,000 0,0138046 0,0276092 ! negative regulation of endothelial cell migration GO:0010596 15 13 0,000 0,0138046 0,02759408 ! fear response GO:0042596 15 13 0,000 0,0138046 0,02757896 ! epithelial cell development GO:0002064 22 13 0,000 0,0138046 0,02756387 ! branching involved in ureteric bud morphogenesis GO:0001658 14 13 0,000 0,0138046 0,02754879 GO:0060675|ureteric bud morphogenesis, ! positive regulation of fatty acid metabolic process GO:0045923 14 13 0,000 0,0138046 0,02753373 ! protein kinase activator activity GO:0030295 17 13 0,000 0,0138046 0,02751868 ! heparan sulfate proteoglycan metabolic process GO:0030201 13 13 0,000 0,0138046 0,02750365 ! positive regulation of foam cell differentiation GO:0010744 16 13 0,000 0,0138046 0,02748864 ! protein targeting to peroxisome GO:0006625 13 13 0,000 0,0138046 0,02747364 ! NLS-bearing substrate import into nucleus GO:0006607 15 13 0,000 0,0138046 0,02745866 ! cranial nerve development GO:0021545 15 13 0,000 0,0138046 0,0274437 ! eye photoreceptor cell differentiation GO:0001754 17 13 0,000 0,0138046 0,02742875 GO:0042462|eye photoreceptor cell development, ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,0138046 0,02741382 ! cerebellum morphogenesis GO:0021587 15 13 0,000 0,0138046 0,02739891 ! MHC class I receptor activity GO:0032393 20 13 0,000 0,0138046 0,02738401 ! exoribonuclease activity GO:0004532 13 13 0,000 0,0138046 0,02736912 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! intrinsic to peroxisomal membrane GO:0031231 13 13 0,000 0,0138046 0,02735426 ! COPI-coated vesicle GO:0030137 15 13 0,000 0,0138046 0,02733941 ! cofactor transporter activity GO:0051184 15 13 0,000 0,0138046 0,02732457 ! NADP metabolic process GO:0006739 15 13 0,000 0,0138046 0,02730976 ! negative regulation of macrophage differentiation GO:0045650 16 13 0,000 0,0138046 0,02729495 ! regulation of osteoclast differentiation GO:0045670 15 13 0,000 0,0138046 0,02728017 ! aromatic amino acid family catabolic process GO:0009074 13 13 0,000 0,0138046 0,0272654 ! eukaryotic cell surface binding GO:0043499 15 13 0,000 0,0138046 0,02725064 ! proximal/distal pattern formation GO:0009954 15 13 0,000 0,0138046 0,02723591 ! positive regulation of JNK cascade GO:0046330 17 13 0,000 0,0138046 0,02722118 ! positive regulation of glucose import GO:0046326 16 13 0,000 0,0138046 0,02720648 GO:0010828|positive regulation of glucose transport, ! epithelial to mesenchymal transition GO:0001837 13 13 0,000 0,0138046 0,02719179 ! ADP binding GO:0043531 15 13 0,000 0,0138046 0,02717711 ! defense response to Gram-positive bacterium GO:0050830 14 13 0,000 0,0138046 0,02716245 ! mismatched DNA binding GO:0030983 13 13 0,000 0,0138046 0,02714781 ! positive regulation of synaptic transmission GO:0050806 15 13 0,000 0,0138046 0,02713318 ! neuron fate specification GO:0048665 25 13 0,000 0,0138046 0,02711857 ! N-terminal protein amino acid modification GO:0031365 14 13 0,000 0,0138046 0,02710398 ! dicarboxylic acid transport GO:0006835 15 13 0,000 0,0138046 0,0270894 ! water transport GO:0006833 18 13 0,000 0,0138046 0,02707483 GO:0042044|fluid transport, ! replisome GO:0030894 24 13 0,000 0,0138046 0,02706028 GO:0043601|nuclear replisome, ! cytosolic calcium ion transport GO:0060401 20 13 0,000 0,0138046 0,02704575 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,0138046 0,02703123 ! inorganic anion exchanger activity GO:0005452 13 13 0,000 0,0138046 0,02701673 ! negative regulation of ion transport GO:0043271 15 13 0,000 0,0138046 0,02700225 ! retinoic acid receptor binding GO:0042974 14 13 0,000 0,0138046 0,02698778 ! blood vessel remodeling GO:0001974 16 13 0,000 0,0138046 0,02697332 ! myoblast differentiation GO:0045445 15 13 0,000 0,0138046 0,02695888 ! ventral spinal cord development GO:0021517 16 13 0,000 0,0138046 0,02694446 ! prenyltransferase activity GO:0004659 15 13 0,000 0,0138046 0,02693005 ! activation of MAPKK activity GO:0000186 13 13 0,000 0,0138046 0,02691565 ! protein histidine kinase activity GO:0004673 15 13 0,000 0,0138046 0,02690128 GO:0000155|two-component sensor activity, ! cullin-RING ubiquitin ligase complex GO:0031461 13 13 0,000 0,0138046 0,02688691 ! regulation of skeletal muscle fiber development GO:0048742 16 13 0,000 0,0138046 0,02687257 ! acyl-CoA dehydrogenase activity GO:0003995 14 13 0,000 0,0138046 0,02685823 ! exocrine system development GO:0035272 14 13 0,000 0,0138046 0,02684392 ! membrane protein proteolysis GO:0033619 14 13 0,000 0,0138046 0,02682962 GO:0006509|membrane protein ectodomain proteolysis, ! organic alcohol transport GO:0015850 17 13 0,000 0,0138046 0,02681533 ! calcium ion transmembrane transporter activity GO:0015085 15 13 0,000 0,0138046 0,02680106 ! L-glutamate transport GO:0015813 14 13 0,000 0,0138046 0,0267868 GO:0015800|acidic amino acid transport, ! embryo implantation GO:0007566 17 13 0,000 0,0138046 0,02677256 ! G1/S transition checkpoint GO:0031575 14 13 0,000 0,0138046 0,02675834 ! immunoglobulin binding GO:0019865 14 13 0,000 0,0138046 0,02674413 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,0138046 0,02672993 ! regulation of T cell mediated immunity GO:0002709 17 13 0,000 0,0138046 0,02671575 ! DNA unwinding during replication GO:0006268 14 13 0,000 0,0138046 0,02670158 ! genitalia development GO:0048806 18 13 0,000 0,0138046 0,02668743 ! regulation of interleukin-8 production GO:0032677 15 13 0,000 0,0138046 0,0266733 ! regulation of interleukin-12 production GO:0032655 13 13 0,000 0,0138046 0,02665918 ! MHC class I protein binding GO:0042288 23 13 0,000 0,0138046 0,02664507 ! histone deacetylation GO:0016575 14 13 0,000 0,0138046 0,02663098 ! calcium channel regulator activity GO:0005246 16 13 0,000 0,0138046 0,02661691 ! DNA methylation GO:0006306 15 13 0,000 0,0138046 0,02660285 GO:0006305|DNA alkylation, ! mRNA splice site selection GO:0006376 17 13 0,000 0,0138046 0,0265888 ! chromatin silencing GO:0006342 13 13 0,000 0,0138046 0,02657477 ! serotonin receptor activity GO:0004993 16 13 0,000 0,0138046 0,02656075 ! monosaccharide transmembrane transporter activity GO:0015145 13 13 0,000 0,0138046 0,02654675 ! T cell homeostasis GO:0043029 14 13 0,000 0,0138046 0,02653277 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,0138046 0,02651879 ! diacylglycerol kinase activity GO:0004143 15 13 0,000 0,0138046 0,02650484 ! response to gamma radiation GO:0010332 14 13 0,000 0,0138046 0,02649089 ! synaptic transmission, cholinergic GO:0007271 14 13 0,000 0,0138046 0,02647697 ! retinoic acid receptor activity GO:0003708 15 13 0,000 0,0138046 0,02646305 ! purine base metabolic process GO:0006144 15 13 0,000 0,0138046 0,02644915 ! cAMP binding GO:0030552 15 13 0,000 0,0138046 0,02643527 ! biogenic amine catabolic process GO:0042402 14 13 0,000 0,0138046 0,0264214 ! negative regulation of BMP signaling pathway GO:0030514 14 13 0,000 0,0138046 0,02640755 ! regulation of axon extension GO:0030516 16 13 0,000 0,0138046 0,0263937 ! drug transporter activity GO:0015238 14 13 0,000 0,0138046 0,02637988 ! regulation of NF-kappaB import into nucleus GO:0042345 14 13 0,000 0,0138046 0,02636607 ! calcium-activated potassium channel activity GO:0015269 15 13 0,000 0,0138046 0,02635227 ! response to cold GO:0009409 13 13 0,000 0,0138046 0,02633849 ! cadherin binding GO:0045296 16 13 0,000 0,0138046 0,02632472 ! nucleolar part GO:0044452 13 13 0,000 0,0138046 0,02631097 ! tRNA modification GO:0006400 14 14 0,000 0,01485896 0,02830574 ! cis-Golgi network GO:0005801 16 14 0,000 0,01485896 0,02829097 ! negative regulation of hormone secretion GO:0046888 14 14 0,000 0,01485896 0,02827621 ! 'de novo' protein folding GO:0006458 14 14 0,000 0,01485896 0,02826147 ! organellar large ribosomal subunit GO:0000315 15 14 0,000 0,01485896 0,02824674 GO:0005762|mitochondrial large ribosomal subunit, ! phosphoinositide phosphorylation GO:0046854 18 14 0,000 0,01485896 0,02823203 ! peroxisomal transport GO:0043574 14 14 0,000 0,01485896 0,02821733 ! cardiac muscle contraction GO:0060048 15 14 0,000 0,01485896 0,02820265 ! dopamine receptor signaling pathway GO:0007212 19 14 0,000 0,01485896 0,02818798 ! mechanoreceptor differentiation GO:0042490 16 14 0,000 0,01485896 0,02817333 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 18 14 0,000 0,01485896 0,0281587 ! pseudouridine synthesis GO:0001522 14 14 0,000 0,01485896 0,02814408 ! positive regulation of cell growth GO:0030307 15 14 0,000 0,01485896 0,02812947 ! caspase activator activity GO:0008656 16 14 0,000 0,01485896 0,02811488 ! MHC class II protein complex GO:0042613 19 14 0,000 0,01485896 0,02810031 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01485896 0,02808575 ! cAMP-dependent protein kinase regulator activity GO:0008603 17 14 0,000 0,01485896 0,0280712 ! cation:cation antiporter activity GO:0015491 14 14 0,000 0,01485896 0,02805667 ! glycoprotein catabolic process GO:0006516 16 14 0,000 0,01485896 0,02804216 ! protein polyubiquitination GO:0000209 15 14 0,000 0,01485896 0,02802766 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 34 14 0,000 0,01485896 0,02801317 ! negative regulation of microtubule depolymerization GO:0007026 16 14 0,000 0,01485896 0,02799871 GO:0031114|regulation of microtubule depolymerization, ! cell-cell junction assembly GO:0007043 15 14 0,000 0,01485896 0,02798425 ! response to vitamin A GO:0033189 18 14 0,000 0,01485896 0,02796981 ! actin filament bundle formation GO:0051017 16 14 0,000 0,01485896 0,02795539 ! regulation of lipoprotein lipase activity GO:0051004 15 14 0,000 0,01485896 0,02794098 ! plasma membrane fusion GO:0045026 15 14 0,000 0,01485896 0,02792658 ! purine nucleoside monophosphate metabolic process GO:0009126 15 14 0,000 0,01485896 0,0279122 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 16 14 0,000 0,01485896 0,02789783 ! protein export from nucleus GO:0006611 14 14 0,000 0,01485896 0,02788348 ! presynaptic membrane GO:0042734 14 14 0,000 0,01485896 0,02786915 ! negative regulation of immune response GO:0050777 21 14 0,000 0,01485896 0,02785483 ! gastrulation with mouth forming second GO:0001702 15 14 0,000 0,01485896 0,02784052 ! neural crest cell migration GO:0001755 15 14 0,000 0,01485896 0,02782623 ! anaphase-promoting complex GO:0005680 17 14 0,000 0,01485896 0,02781195 ! positive regulation of oxidoreductase activity GO:0051353 14 14 0,000 0,01485896 0,02779769 ! negative regulation of protein secretion GO:0050709 17 14 0,000 0,01485896 0,02778344 ! cofactor transport GO:0051181 16 14 0,000 0,01485896 0,02776921 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,01485896 0,02775499 ! protein-chromophore linkage GO:0018298 16 14 0,000 0,01485896 0,02774078 ! cobalt ion binding GO:0050897 14 14 0,000 0,01485896 0,02772659 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01485896 0,02771242 ! positive regulation of transmission of nerve impulse GO:0051971 16 14 0,000 0,01485896 0,02769826 ! aspartate family amino acid biosynthetic process GO:0009067 17 14 0,000 0,01485896 0,02768411 ! gas transport GO:0015669 15 14 0,000 0,01485896 0,02766998 ! pyridine nucleotide biosynthetic process GO:0019363 15 14 0,000 0,01485896 0,02765586 ! heme biosynthetic process GO:0006783 14 14 0,000 0,01485896 0,02764176 ! release of cytochrome c from mitochondria GO:0001836 26 14 0,000 0,01485896 0,02762767 ! cerebellar cortex development GO:0021695 16 14 0,000 0,01485896 0,0276136 ! insulin secretion GO:0030073 17 14 0,000 0,01485896 0,02759954 ! tRNA binding GO:0000049 16 14 0,000 0,01485896 0,02758549 ! positive regulation of cell killing GO:0031343 16 14 0,000 0,01485896 0,02757146 ! positive regulation of protein complex assembly GO:0031334 14 14 0,000 0,01485896 0,02755744 ! G1 phase of mitotic cell cycle GO:0000080 15 14 0,000 0,01485896 0,02754344 ! phosphatidylinositol metabolic process GO:0046488 15 14 0,000 0,01485896 0,02752945 ! regulation of B cell proliferation GO:0030888 18 14 0,000 0,01485896 0,02751548 ! regulation of neuronal synaptic plasticity GO:0048168 24 14 0,000 0,01485896 0,02750152 ! MAP kinase activity GO:0004707 16 14 0,000 0,01485896 0,02748757 ! cytokine biosynthetic process GO:0042089 14 14 0,000 0,01485896 0,02747364 ! mannosyltransferase activity GO:0000030 14 14 0,000 0,01485896 0,02745972 ! isoprenoid biosynthetic process GO:0008299 17 14 0,000 0,01485896 0,02744582 ! C-C chemokine binding GO:0019957 15 14 0,000 0,01485896 0,02743193 GO:0016493|C-C chemokine receptor activity, ! cardiac muscle tissue development GO:0048738 16 14 0,000 0,01485896 0,02741805 ! complement activation, alternative pathway GO:0006957 14 14 0,000 0,01485896 0,02740419 ! response to osmotic stress GO:0006970 17 14 0,000 0,01485896 0,02739035 ! fructose metabolic process GO:0006000 15 14 0,000 0,01485896 0,02737651 ! telomeric DNA binding GO:0042162 17 14 0,000 0,01485896 0,02736269 ! monoamine transport GO:0015844 15 14 0,000 0,01485896 0,02734889 ! regulation of pathway-restricted SMAD protein phosphorylation GO:0060393 14 14 0,000 0,01485896 0,02733509 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,01485896 0,02732132 ! dendritic spine GO:0043197 15 14 0,000 0,01485896 0,02730755 ! stem cell development GO:0048864 14 14 0,000 0,01485896 0,0272938 GO:0019827|stem cell maintenance, ! regulation of alpha-beta T cell activation GO:0046634 15 14 0,000 0,01485896 0,02728007 ! regulation of insulin receptor signaling pathway GO:0046626 17 14 0,000 0,01485896 0,02726634 ! regulation of cytokine production during immune response GO:0002718 15 14 0,000 0,01485896 0,02725264 ! positive regulation of protein import into nucleus GO:0042307 16 14 0,000 0,01485896 0,02723894 ! regulation of cellular pH GO:0030641 14 14 0,000 0,01485896 0,02722526 ! regulation of monooxygenase activity GO:0032768 14 14 0,000 0,01485896 0,02721159 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,01485896 0,02719794 ! sarcoplasmic reticulum membrane GO:0033017 16 14 0,000 0,01485896 0,0271843 ! detection of biotic stimulus GO:0009595 16 14 0,000 0,01485896 0,02717067 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 16 14 0,000 0,01485896 0,02715706 ! mannosidase activity GO:0015923 19 14 0,000 0,01485896 0,02714346 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 17 14 0,000 0,01485896 0,02712988 ! negative regulation of tissue remodeling GO:0034104 16 14 0,000 0,01485896 0,0271163 ! positive regulation of bone mineralization GO:0030501 14 14 0,000 0,01485896 0,02710275 ! neuromuscular synaptic transmission GO:0007274 15 14 0,000 0,01485896 0,0270892 ! regulation of immunoglobulin production GO:0002637 15 14 0,000 0,01485896 0,02707567 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,01485896 0,02706215 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 16 14 0,000 0,01485896 0,02704865 ! fucosyltransferase activity GO:0008417 16 14 0,000 0,01485896 0,02703516 ! sperm-egg recognition GO:0035036 17 14 0,000 0,01485896 0,02702168 GO:0007339|binding of sperm to zona pellucida, ! defense response to virus GO:0051607 21 14 0,000 0,01485896 0,02700822 ! SWI/SNF-type complex GO:0070603 16 14 0,000 0,01485896 0,02699477 GO:0016514|SWI/SNF complex, ! aldo-keto reductase activity GO:0004033 15 14 0,000 0,01485896 0,02698133 ! positive regulation of translation GO:0045727 17 15 0,000 0,01591225 0,02887955 ! nuclear replication fork GO:0043596 26 15 0,000 0,01591225 0,02886519 ! transferase activity, transferring amino-acyl groups GO:0016755 15 15 0,000 0,01591225 0,02885084 ! 2'-deoxyribonucleotide metabolic process GO:0009394 16 15 0,000 0,01591225 0,02883651 GO:0019692|deoxyribose phosphate metabolic process, ! phospholipid catabolic process GO:0009395 26 15 0,000 0,01591225 0,02882219 ! endothelial cell migration GO:0043542 16 15 0,000 0,01591225 0,02880789 ! lipid phosphorylation GO:0046834 19 15 0,000 0,01591225 0,0287936 ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,01591225 0,02877932 ! response to vitamin GO:0033273 19 15 0,000 0,01591225 0,02876506 ! gene silencing by RNA GO:0031047 17 15 0,000 0,01591225 0,02875081 ! striated muscle thick filament GO:0005863 16 15 0,000 0,01591225 0,02873658 GO:0032982|myosin filament, ! cellular response to hydrogen peroxide GO:0070301 15 15 0,000 0,01591225 0,02872236 GO:0042744|hydrogen peroxide catabolic process, ! endocrine pancreas development GO:0031018 16 15 0,000 0,01591225 0,02870816 ! regulation of interleukin-2 biosynthetic process GO:0045076 15 15 0,000 0,01591225 0,02869396 ! glutamate metabolic process GO:0006536 17 15 0,000 0,01591225 0,02867979 ! pituitary gland development GO:0021983 16 15 0,000 0,01591225 0,02866563 ! cholesterol binding GO:0015485 15 15 0,000 0,01591225 0,02865148 ! NAD metabolic process GO:0019674 17 15 0,000 0,01591225 0,02863734 ! protease binding GO:0002020 20 15 0,000 0,01591225 0,02862322 ! regulation of heart rate GO:0002027 20 15 0,000 0,01591225 0,02860911 ! actin filament bundle GO:0032432 18 15 0,000 0,01591225 0,02859502 GO:0001725|stress fiber, ! Golgi cisterna GO:0031985 17 15 0,000 0,01591225 0,02858094 ! regulation of exocytosis GO:0017157 16 15 0,000 0,01591225 0,02856688 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,01591225 0,02855282 ! embryonic digit morphogenesis GO:0042733 17 15 0,000 0,01591225 0,02853879 ! positive regulation of biomineral formation GO:0070169 15 15 0,000 0,01591225 0,02852476 ! prostaglandin metabolic process GO:0006693 15 15 0,000 0,01591225 0,02851075 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 20 15 0,000 0,01591225 0,02849676 ! neuron recognition GO:0008038 18 15 0,000 0,01591225 0,02848277 ! regulation of Rho GTPase activity GO:0032319 18 15 0,000 0,01591225 0,0284688 ! hindbrain morphogenesis GO:0021575 18 15 0,000 0,01591225 0,02845485 ! filopodium GO:0030175 17 15 0,000 0,01591225 0,02844091 ! negative regulation of blood coagulation GO:0030195 18 15 0,000 0,01591225 0,02842698 ! folic acid and derivative metabolic process GO:0006760 15 15 0,000 0,01591225 0,02841306 ! positive regulation of neuron differentiation GO:0045666 27 15 0,000 0,01591225 0,02839916 ! peptide hormone binding GO:0017046 16 15 0,000 0,01591225 0,02838528 ! regulation of ATPase activity GO:0043462 17 15 0,000 0,01591225 0,0283714 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 16 15 0,000 0,01591225 0,02835754 ! regulation of leukocyte mediated cytotoxicity GO:0001910 21 15 0,000 0,01591225 0,0283437 ! acid-thiol ligase activity GO:0016878 16 15 0,000 0,01591225 0,02832986 ! aromatic compound biosynthetic process GO:0019438 25 15 0,000 0,01591225 0,02831604 ! positive regulation of calcium ion transport GO:0051928 20 15 0,000 0,01591225 0,02830224 ! dystrophin-associated glycoprotein complex GO:0016010 17 15 0,000 0,01591225 0,02828845 ! RNA 3'-end processing GO:0031123 16 15 0,000 0,01591225 0,02827467 ! developmental induction GO:0031128 17 15 0,000 0,01591225 0,0282609 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 17 15 0,000 0,01591225 0,02824715 ! protein import into nucleus, docking GO:0000059 15 15 0,000 0,01591225 0,02823341 ! regulation of skeletal muscle tissue development GO:0048641 18 15 0,000 0,01591225 0,02821968 ! lactation GO:0007595 17 15 0,000 0,01591225 0,02820597 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 16 15 0,000 0,01591225 0,02819227 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01591225 0,02817859 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,01591225 0,02816492 ! double-strand break repair via homologous recombination GO:0000724 36 15 0,000 0,01591225 0,02815126 GO:0000725|recombinational repair, ! phosphatidylcholine metabolic process GO:0046470 16 15 0,000 0,01591225 0,02813761 ! regulation of cell-cell adhesion GO:0022407 18 15 0,000 0,01591225 0,02812398 ! sulfate transport GO:0008272 16 15 0,000 0,01591225 0,02811036 ! hindlimb morphogenesis GO:0035137 17 15 0,000 0,01591225 0,02809675 ! bile acid metabolic process GO:0008206 17 15 0,000 0,01591225 0,02808316 ! very-low-density lipoprotein particle GO:0034361 16 15 0,000 0,01591225 0,02806958 GO:0034385|triglyceride-rich lipoprotein particle, ! adult walking behavior GO:0007628 19 15 0,000 0,01591225 0,02805601 ! 2 iron, 2 sulfur cluster binding GO:0051537 16 15 0,000 0,01591225 0,02804246 ! heart looping GO:0001947 18 15 0,000 0,01591225 0,02802892 ! protein kinase C activity GO:0004697 17 15 0,000 0,01591225 0,02801539 ! oligodendrocyte differentiation GO:0048709 15 15 0,000 0,01591225 0,02800188 ! regulation of striated muscle contraction GO:0006942 18 15 0,000 0,01591225 0,02798838 ! pigmentation during development GO:0048066 17 15 0,000 0,01591225 0,02797489 ! cytokine metabolic process GO:0042107 15 15 0,000 0,01591225 0,02796141 ! vesicle coating GO:0006901 17 15 0,000 0,01591225 0,02794795 ! disulfide oxidoreductase activity GO:0015036 16 15 0,000 0,01591225 0,0279345 ! neutral amino acid transport GO:0015804 18 15 0,000 0,01591225 0,02792106 ! L-amino acid transport GO:0015807 16 15 0,000 0,01591225 0,02790764 ! microfilament motor activity GO:0000146 15 15 0,000 0,01591225 0,02789423 ! carbonate dehydratase activity GO:0004089 18 15 0,000 0,01591225 0,02788083 ! regulation of vasodilation GO:0042312 25 15 0,000 0,01591225 0,02786745 ! DNA replication initiation GO:0006270 15 15 0,000 0,01591225 0,02785407 ! taste receptor activity GO:0008527 15 15 0,000 0,01591225 0,02784071 ! cellular pigmentation GO:0033059 16 15 0,000 0,01591225 0,02782737 ! voltage-gated chloride channel activity GO:0005247 18 15 0,000 0,01591225 0,02781403 ! voltage-gated sodium channel activity GO:0005248 18 15 0,000 0,01591225 0,02780071 ! long-chain fatty acid transport GO:0015909 17 15 0,000 0,01591225 0,02778741 ! positive regulation of neurological system process GO:0031646 18 15 0,000 0,01591225 0,02777411 ! nerve-nerve synaptic transmission GO:0007270 17 15 0,000 0,01591225 0,02776083 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 17 15 0,000 0,01591225 0,02774756 ! ion gated channel activity GO:0022839 17 15 0,000 0,01591225 0,0277343 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 15 15 0,000 0,01591225 0,02772106 ! receptor activator activity GO:0030546 17 15 0,000 0,01591225 0,02770782 ! protein transmembrane transporter activity GO:0008320 16 15 0,000 0,01591225 0,0276946 ! negative regulation of mast cell proliferation GO:0070667 16 15 0,000 0,01591225 0,0276814 GO:0042130|negative regulation of T cell proliferation, ! acylglycerol O-acyltransferase activity GO:0016411 16 15 0,000 0,01591225 0,0276682 ! triacylglycerol lipase activity GO:0004806 16 15 0,000 0,01591225 0,02765502 ! peptide hormone processing GO:0016486 19 15 0,000 0,01591225 0,02764185 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,01591225 0,0276287 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 19 16 0,000 0,01696447 0,02944167 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,01696447 0,02942767 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 18 16 0,000 0,01696447 0,02941368 ! heterophilic cell adhesion GO:0007157 17 16 0,000 0,01696447 0,02939971 ! gamma-aminobutyric acid signaling pathway GO:0007214 17 16 0,000 0,01696447 0,02938575 ! kinesin complex GO:0005871 16 16 0,000 0,01696447 0,0293718 ! photoreceptor cell development GO:0042461 22 16 0,000 0,01696447 0,02935787 GO:0046530|photoreceptor cell differentiation, ! negative regulation of gene expression, epigenetic GO:0045814 16 16 0,000 0,01696447 0,02934395 ! mitotic chromosome condensation GO:0007076 17 16 0,000 0,01696447 0,02933004 ! centrosome cycle GO:0007098 26 16 0,000 0,01696447 0,02931615 ! negative regulation of epithelial cell proliferation GO:0050680 18 16 0,000 0,01696447 0,02930227 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 16 0,000 0,01696447 0,0292884 ! DNA duplex unwinding GO:0032508 17 16 0,000 0,01696447 0,02927454 GO:0032392|DNA geometric change, ! cerebral cortex development GO:0021987 16 16 0,000 0,01696447 0,0292607 ! lysosomal transport GO:0007041 16 16 0,000 0,01696447 0,02924687 ! transforming growth factor beta receptor activity GO:0005024 18 16 0,000 0,01696447 0,02923306 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! rough endoplasmic reticulum GO:0005791 16 16 0,000 0,01696447 0,02921926 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 16 16 0,000 0,01696447 0,02920547 ! small nucleolar ribonucleoprotein complex GO:0005732 16 16 0,000 0,01696447 0,02919169 ! myofibril assembly GO:0030239 17 16 0,000 0,01696447 0,02917793 GO:0055002|striated muscle cell development, ! protein serine/threonine kinase inhibitor activity GO:0030291 17 16 0,000 0,01696447 0,02916418 ! G1 phase GO:0051318 17 16 0,000 0,01696447 0,02915044 ! receptor signaling complex scaffold activity GO:0030159 19 16 0,000 0,01696447 0,02913672 ! negative regulation of inflammatory response GO:0050728 17 16 0,000 0,01696447 0,029123 ! clathrin vesicle coat GO:0030125 20 16 0,000 0,01696447 0,02910931 ! endodeoxyribonuclease activity GO:0004520 43 16 0,000 0,01696447 0,02909562 ! sphingolipid catabolic process GO:0030149 18 16 0,000 0,01696447 0,02908195 GO:0046466|membrane lipid catabolic process, ! natural killer cell activation GO:0030101 17 16 0,000 0,01696447 0,02906829 ! steroid catabolic process GO:0006706 18 16 0,000 0,01696447 0,02905464 ! branched chain family amino acid metabolic process GO:0009081 18 16 0,000 0,01696447 0,02904101 ! cell-cell recognition GO:0009988 19 16 0,000 0,01696447 0,02902739 ! somatic diversification of immune receptors GO:0002200 17 16 0,000 0,01696447 0,02901378 ! spleen development GO:0048536 19 16 0,000 0,01696447 0,02900018 ! lymphocyte homeostasis GO:0002260 17 16 0,000 0,01696447 0,0289866 ! regulation of fatty acid oxidation GO:0046320 19 16 0,000 0,01696447 0,02897303 ! neural tube closure GO:0001843 19 16 0,000 0,01696447 0,02895947 GO:0060606|tube closure, ! antigen receptor-mediated signaling pathway GO:0050851 22 16 0,000 0,01696447 0,02894592 ! regulation of protein ubiquitination GO:0031396 27 16 0,000 0,01696447 0,02893239 ! regulation of glucose metabolic process GO:0010906 18 16 0,000 0,01696447 0,02891887 ! regulation of lipid catabolic process GO:0050994 18 16 0,000 0,01696447 0,02890536 ! viral genome replication GO:0019079 16 16 0,000 0,01696447 0,02889187 ! regulation of neurotransmitter transport GO:0051588 19 16 0,000 0,01696447 0,02887839 ! memory GO:0007613 18 16 0,000 0,01696447 0,02886492 ! regulation of carbohydrate biosynthetic process GO:0043255 17 16 0,000 0,01696447 0,02885146 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01696447 0,02883802 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 18 16 0,000 0,01696447 0,02882459 ! glycoprotein binding GO:0001948 19 16 0,000 0,01696447 0,02881117 ! negative regulation of endothelial cell proliferation GO:0001937 17 16 0,000 0,01696447 0,02879776 ! syntaxin binding GO:0019905 18 16 0,000 0,01696447 0,02878437 ! myosin binding GO:0017022 17 16 0,000 0,01696447 0,02877098 ! epidermis morphogenesis GO:0048730 18 16 0,000 0,01696447 0,02875761 ! fucose metabolic process GO:0006004 18 16 0,000 0,01696447 0,02874426 ! actin polymerization or depolymerization GO:0008154 18 16 0,000 0,01696447 0,02873091 ! membrane budding GO:0006900 18 16 0,000 0,01696447 0,02871758 ! preassembly of GPI anchor in ER membrane GO:0016254 18 16 0,000 0,01696447 0,02870426 ! intermediate filament cytoskeleton organization GO:0045104 16 16 0,000 0,01696447 0,02869095 ! behavioral interaction between organisms GO:0051705 19 16 0,000 0,01696447 0,02867766 ! nucleotide-excision repair, DNA gap filling GO:0006297 19 16 0,000 0,01696447 0,02866437 ! anchored to plasma membrane GO:0046658 20 16 0,000 0,01696447 0,0286511 ! calcium activated cation channel activity GO:0005227 18 16 0,000 0,01696447 0,02863785 ! DNA fragmentation involved in apoptosis GO:0006309 18 16 0,000 0,01696447 0,0286246 ! apoptotic protease activator activity GO:0016505 18 16 0,000 0,01696447 0,02861137 ! sulfuric ester hydrolase activity GO:0008484 18 16 0,000 0,01696447 0,02859814 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 18 16 0,000 0,01696447 0,02858494 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,01696447 0,02857174 ! RNA polymerase II transcription mediator activity GO:0016455 19 16 0,000 0,01696447 0,02855855 ! axoneme GO:0005930 16 16 0,000 0,01696447 0,02854538 ! negative regulation of homeostatic process GO:0032845 19 16 0,000 0,01696447 0,02853222 ! anion exchanger activity GO:0015380 17 17 0,000 0,01801562 0,03028617 ! positive regulation of hormone secretion GO:0046887 19 17 0,000 0,01801562 0,03027222 ! skin development GO:0043588 20 17 0,000 0,01801562 0,03025828 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 17 17 0,000 0,01801562 0,03024435 ! transcription from RNA polymerase III promoter GO:0006383 18 17 0,000 0,01801562 0,03023044 ! glial cell development GO:0021782 17 17 0,000 0,01801562 0,03021654 ! limbic system development GO:0021761 18 17 0,000 0,01801562 0,03020266 ! protein phosphatase type 2A regulator activity GO:0008601 19 17 0,000 0,01801562 0,03018878 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 17 0,000 0,01801562 0,03017492 ! ephrin receptor activity GO:0005003 21 17 0,000 0,01801562 0,03016107 ! acetylcholine receptor activity GO:0015464 18 17 0,000 0,01801562 0,03014724 ! glutamine metabolic process GO:0006541 26 17 0,000 0,01801562 0,03013342 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 21 17 0,000 0,01801562 0,03011961 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 37 17 0,000 0,01801562 0,03010581 ! signal sequence binding GO:0005048 18 17 0,000 0,01801562 0,03009202 ! cell-substrate junction assembly GO:0007044 21 17 0,000 0,01801562 0,03007825 ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,01801562 0,03006449 ! organelle subcompartment GO:0031984 19 17 0,000 0,01801562 0,03005075 ! regulation of dephosphorylation GO:0035303 20 17 0,000 0,01801562 0,03003701 ! regulation of vasoconstriction GO:0019229 21 17 0,000 0,01801562 0,03002329 ! membrane depolarization GO:0051899 19 17 0,000 0,01801562 0,03000958 ! oogenesis GO:0048477 20 17 0,000 0,01801562 0,02999588 ! nuclear outer membrane GO:0005640 21 17 0,000 0,01801562 0,0299822 ! regulation of immunoglobulin mediated immune response GO:0002889 18 17 0,000 0,01801562 0,02996853 GO:0002712|regulation of B cell mediated immunity, ! immunoglobulin production GO:0002377 21 17 0,000 0,01801562 0,02995487 GO:0002440|production of molecular mediator of immune response, ! positive regulation of cellular carbohydrate metabolic process GO:0010676 18 17 0,000 0,01801562 0,02994122 ! positive regulation of macrophage differentiation GO:0045651 21 17 0,000 0,01801562 0,02992759 ! organic cation transport GO:0015695 17 17 0,000 0,01801562 0,02991396 ! porphyrin biosynthetic process GO:0006779 17 17 0,000 0,01801562 0,02990036 GO:0033014|tetrapyrrole biosynthetic process, ! phosphatidylinositol binding GO:0005545 21 17 0,000 0,01801562 0,02988676 ! hyaluronic acid binding GO:0005540 19 17 0,000 0,01801562 0,02987317 ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 17 0,000 0,01801562 0,0298596 ! negative regulation of coagulation GO:0050819 20 17 0,000 0,01801562 0,02984604 ! cellular monovalent inorganic cation homeostasis GO:0030004 18 17 0,000 0,01801562 0,02983249 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 17 0,000 0,01801562 0,02981896 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 17 0,000 0,01801562 0,02980543 ! negative regulation of defense response GO:0031348 19 17 0,000 0,01801562 0,02979192 ! lipid localization GO:0010876 19 17 0,000 0,01801562 0,02977842 GO:0019915|lipid storage, ! tube lumen formation GO:0035148 20 17 0,000 0,01801562 0,02976494 ! negative regulation of cytokine biosynthetic process GO:0042036 18 17 0,000 0,01801562 0,02975146 ! regulation of systemic arterial blood pressure by hormone GO:0001990 17 17 0,000 0,01801562 0,029738 GO:0050886|endocrine process, ! MAP kinase kinase kinase activity GO:0004709 19 17 0,000 0,01801562 0,02972455 ! negative regulation of protein amino acid phosphorylation GO:0001933 19 17 0,000 0,01801562 0,02971111 ! protein phosphatase type 2A complex GO:0000159 21 17 0,000 0,01801562 0,02969769 ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 22 17 0,000 0,01801562 0,02968427 ! response to hexose stimulus GO:0009746 20 17 0,000 0,01801562 0,02967087 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! transmembrane receptor protein phosphatase activity GO:0019198 24 17 0,000 0,01801562 0,02965748 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! AMP binding GO:0016208 19 17 0,000 0,01801562 0,0296441 ! UDP-galactosyltransferase activity GO:0035250 19 17 0,000 0,01801562 0,02963074 ! receptor metabolic process GO:0043112 20 17 0,000 0,01801562 0,02961739 ! neurotransmitter metabolic process GO:0042133 20 17 0,000 0,01801562 0,02960405 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 23 17 0,000 0,01801562 0,02959072 ! alcohol binding GO:0043178 20 17 0,000 0,01801562 0,0295774 ! T cell differentiation in the thymus GO:0033077 28 17 0,000 0,01801562 0,02956409 ! visual learning GO:0008542 31 17 0,000 0,01801562 0,0295508 ! structural constituent of eye lens GO:0005212 20 17 0,000 0,01801562 0,02953752 ! cellular amino acid derivative catabolic process GO:0042219 19 17 0,000 0,01801562 0,02952425 ! neutrophil chemotaxis GO:0030593 17 17 0,000 0,01801562 0,02951099 ! protein localization in mitochondrion GO:0070585 19 17 0,000 0,01801562 0,02949775 GO:0006626|protein targeting to mitochondrion, ! aspartic-type endopeptidase activity GO:0004190 18 17 0,000 0,01801562 0,02948451 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 19 17 0,000 0,01801562 0,02947129 ! proton-transporting ATP synthase complex GO:0045259 17 17 0,000 0,01801562 0,02945808 ! translation elongation factor activity GO:0003746 19 17 0,000 0,01801562 0,02944488 ! histone binding GO:0042393 26 17 0,000 0,01801562 0,0294317 ! cilium assembly GO:0042384 18 17 0,000 0,01801562 0,02941852 ! transforming growth factor beta receptor binding GO:0005160 19 17 0,000 0,01801562 0,02940536 ! positive regulation of homeostatic process GO:0032846 23 17 0,000 0,01801562 0,02939221 ! solute:hydrogen antiporter activity GO:0015299 18 17 0,000 0,01801562 0,02937907 ! protein secretion GO:0009306 19 18 0,000 0,0190657 0,03107761 ! positive regulation of cell size GO:0045793 19 18 0,000 0,0190657 0,03106373 ! positive regulation of ossification GO:0045778 19 18 0,000 0,0190657 0,03104986 ! positive regulation of angiogenesis GO:0045766 19 18 0,000 0,0190657 0,031036 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,0190657 0,03102216 GO:0005763|mitochondrial small ribosomal subunit, ! protein amino acid deacetylation GO:0006476 19 18 0,000 0,0190657 0,03100833 ! protein amino acid acetylation GO:0006473 21 18 0,000 0,0190657 0,03099451 ! positive regulation of nucleocytoplasmic transport GO:0046824 20 18 0,000 0,0190657 0,0309807 ! cAMP metabolic process GO:0046058 18 18 0,000 0,0190657 0,03096691 ! regulation of muscle cell differentiation GO:0051147 21 18 0,000 0,0190657 0,03095313 ! cornified envelope GO:0001533 22 18 0,000 0,0190657 0,03093936 ! retinoid metabolic process GO:0001523 19 18 0,000 0,0190657 0,0309256 GO:0016101|diterpenoid metabolic process, ! actomyosin GO:0042641 21 18 0,000 0,0190657 0,03091186 ! positive regulation of proteolysis GO:0045862 20 18 0,000 0,0190657 0,03089813 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 18 0,000 0,0190657 0,03088441 ! calcium-dependent protein binding GO:0048306 20 18 0,000 0,0190657 0,0308707 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 18 18 0,000 0,0190657 0,030857 ! proton-transporting V-type ATPase complex GO:0033176 18 18 0,000 0,0190657 0,03084332 ! pyrimidine ribonucleoside metabolic process GO:0046131 23 18 0,000 0,0190657 0,03082965 ! regulation of ion transmembrane transporter activity GO:0032412 21 18 0,000 0,0190657 0,03081599 ! positive regulation of carbohydrate metabolic process GO:0045913 19 18 0,000 0,0190657 0,03080234 ! primary neural tube formation GO:0014020 21 18 0,000 0,0190657 0,0307887 ! recycling endosome GO:0055037 22 18 0,000 0,0190657 0,03077508 ! muscle cell development GO:0055001 20 18 0,000 0,0190657 0,03076147 ! kinase activator activity GO:0019209 22 18 0,000 0,0190657 0,03074787 ! positive regulation of T cell differentiation GO:0045582 28 18 0,000 0,0190657 0,03073428 ! cerebellum development GO:0021549 20 18 0,000 0,0190657 0,03072071 ! positive regulation of multicellular organism growth GO:0040018 19 18 0,000 0,0190657 0,03070714 ! somitogenesis GO:0001756 20 18 0,000 0,0190657 0,03069359 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,0190657 0,03068005 ! low-density lipoprotein binding GO:0030169 19 18 0,000 0,0190657 0,03066653 ! positive regulation of cytokine secretion GO:0050715 21 18 0,000 0,0190657 0,03065301 ! negative regulation of intracellular transport GO:0032387 20 18 0,000 0,0190657 0,03063951 ! glutamine family amino acid catabolic process GO:0009065 21 18 0,000 0,0190657 0,03062602 ! basal plasma membrane GO:0009925 21 18 0,000 0,0190657 0,03061254 GO:0045178|basal part of cell, ! vitamin D receptor binding GO:0042809 20 18 0,000 0,0190657 0,03059907 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 19 18 0,000 0,0190657 0,03058561 ! embryonic organ morphogenesis GO:0048562 22 18 0,000 0,0190657 0,03057217 ! negative regulation of translation GO:0017148 31 18 0,000 0,0190657 0,03055873 ! regulation of cell killing GO:0031341 24 18 0,000 0,0190657 0,03054531 ! positive regulation of cellular catabolic process GO:0031331 20 18 0,000 0,0190657 0,03053191 ! nuclear chromosome, telomeric region GO:0000784 30 18 0,000 0,0190657 0,03051851 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 19 18 0,000 0,0190657 0,03050512 ! intra-Golgi vesicle-mediated transport GO:0006891 20 18 0,000 0,0190657 0,03049175 ! protein complex scaffold GO:0032947 22 18 0,000 0,0190657 0,03047839 ! SNAP receptor activity GO:0005484 21 18 0,000 0,0190657 0,03046504 ! dendrite development GO:0016358 22 18 0,000 0,0190657 0,0304517 ! cell differentiation in spinal cord GO:0021515 21 18 0,000 0,0190657 0,03043837 ! inactivation of MAPK activity GO:0000188 20 18 0,000 0,0190657 0,03042506 ! calmodulin-dependent protein kinase activity GO:0004683 20 18 0,000 0,0190657 0,03041175 ! D-ribose metabolic process GO:0006014 19 18 0,000 0,0190657 0,03039846 ! nuclear ubiquitin ligase complex GO:0000152 31 18 0,000 0,0190657 0,03038518 ! glucuronosyltransferase activity GO:0015020 18 18 0,000 0,0190657 0,03037191 ! coreceptor activity GO:0015026 28 18 0,000 0,0190657 0,03035866 ! response to fungus GO:0009620 18 18 0,000 0,0190657 0,03034541 ! stem cell differentiation GO:0048863 18 18 0,000 0,0190657 0,03033218 ! intermediate filament-based process GO:0045103 18 18 0,000 0,0190657 0,03031895 ! heart process GO:0003015 19 18 0,000 0,0190657 0,03030574 GO:0060047|heart contraction, ! mismatch repair GO:0006298 28 18 0,000 0,0190657 0,03029254 ! vasodilation GO:0042311 20 18 0,000 0,0190657 0,03027936 ! transport vesicle membrane GO:0030658 23 18 0,000 0,0190657 0,03026618 ! MHC protein binding GO:0042287 30 18 0,000 0,0190657 0,03025301 ! inward rectifier potassium channel activity GO:0005242 22 18 0,000 0,0190657 0,03023986 ! chloride transmembrane transporter activity GO:0015108 19 18 0,000 0,0190657 0,03022672 ! bicarbonate transmembrane transporter activity GO:0015106 18 18 0,000 0,0190657 0,03021359 ! ionotropic glutamate receptor activity GO:0004970 22 18 0,000 0,0190657 0,03020047 ! cell-cell adherens junction GO:0005913 20 18 0,000 0,0190657 0,03018736 ! negative regulation of leukocyte proliferation GO:0070664 20 18 0,000 0,0190657 0,03017426 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! ubiquitin-specific protease activity GO:0004843 19 18 0,000 0,0190657 0,03016118 ! ATP-dependent RNA helicase activity GO:0004004 28 18 0,000 0,0190657 0,03014811 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 24 19 0,000 0,02011472 0,03179311 ! pteridine and derivative metabolic process GO:0042558 29 19 0,000 0,02011472 0,03177934 ! proteasome core complex GO:0005839 20 19 0,000 0,02011472 0,03176558 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 22 19 0,000 0,02011472 0,03175183 ! anion:anion antiporter activity GO:0015301 19 19 0,000 0,02011472 0,0317381 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 24 19 0,000 0,02011472 0,03172438 ! regulation of transmembrane transporter activity GO:0022898 22 19 0,000 0,02011472 0,03171067 GO:0032409|regulation of transporter activity, ! regulation of survival gene product expression GO:0045884 23 19 0,000 0,02011472 0,03169697 ! activation of pro-apoptotic gene products GO:0008633 26 19 0,000 0,02011472 0,03168329 ! deoxyribonucleotide metabolic process GO:0009262 20 19 0,000 0,02011472 0,03166961 ! lysosome organization GO:0007040 20 19 0,000 0,02011472 0,03165595 ! cellular macromolecular complex disassembly GO:0034623 23 19 0,000 0,02011472 0,0316423 ! central nervous system neuron development GO:0021954 21 19 0,000 0,02011472 0,03162866 ! threonine-type endopeptidase activity GO:0004298 20 19 0,000 0,02011472 0,03161503 GO:0070003|threonine-type peptidase activity, ! chromosome condensation GO:0030261 20 19 0,000 0,02011472 0,03160142 ! peptidyl-serine phosphorylation GO:0018105 26 19 0,000 0,02011472 0,03158781 ! regulation of endothelial cell migration GO:0010594 22 19 0,000 0,02011472 0,03157422 ! fatty acid beta-oxidation GO:0006635 21 19 0,000 0,02011472 0,03156064 ! ventricular cardiac muscle morphogenesis GO:0055010 21 19 0,000 0,02011472 0,03154707 ! beta-catenin binding GO:0008013 23 19 0,000 0,02011472 0,03153351 ! positive regulation of locomotion GO:0040017 21 19 0,000 0,02011472 0,03151997 GO:0050921|positive regulation of chemotaxis, ! cell projection membrane GO:0031253 21 19 0,000 0,02011472 0,03150644 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,02011472 0,03149291 ! trans-Golgi network transport vesicle GO:0030140 26 19 0,000 0,02011472 0,0314794 ! sphingolipid biosynthetic process GO:0030148 20 19 0,000 0,02011472 0,0314659 ! vitamin transport GO:0051180 21 19 0,000 0,02011472 0,03145242 ! positive regulation of osteoblast differentiation GO:0045669 22 19 0,000 0,02011472 0,03143894 ! terpenoid metabolic process GO:0006721 20 19 0,000 0,02011472 0,03142548 ! leukotriene biosynthetic process GO:0019370 20 19 0,000 0,02011472 0,03141202 GO:0043450|alkene biosynthetic process, ! nerve development GO:0021675 24 19 0,000 0,02011472 0,03139858 ! retinoid binding GO:0005501 19 19 0,000 0,02011472 0,03138515 GO:0019840|isoprenoid binding, ! regulation of amine transport GO:0051952 23 19 0,000 0,02011472 0,03137174 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 22 19 0,000 0,02011472 0,03135833 ! histone deacetylase activity GO:0004407 20 19 0,000 0,02011472 0,03134493 GO:0033558|protein deacetylase activity, ! regulation of microtubule polymerization or depolymerization GO:0031110 21 19 0,000 0,02011472 0,03133155 ! positive regulation of fibroblast proliferation GO:0048146 25 19 0,000 0,02011472 0,03131818 ! gluconeogenesis GO:0006094 23 19 0,000 0,02011472 0,03130482 ! microtubule-based transport GO:0010970 20 19 0,000 0,02011472 0,03129147 ! superoxide metabolic process GO:0006801 21 19 0,000 0,02011472 0,03127813 ! C21-steroid hormone metabolic process GO:0008207 20 19 0,000 0,02011472 0,0312648 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,02011472 0,03125149 GO:0006479|protein amino acid methylation, ! L-ascorbic acid binding GO:0031418 19 19 0,000 0,02011472 0,03123818 ! regulation of DNA recombination GO:0000018 38 19 0,000 0,02011472 0,03122489 ! photoreceptor cell maintenance GO:0045494 23 19 0,000 0,02011472 0,03121161 ! positive regulation of cytoskeleton organization GO:0051495 22 19 0,000 0,02011472 0,03119834 ! acetylcholine binding GO:0042166 20 19 0,000 0,02011472 0,03118508 ! heme metabolic process GO:0042168 20 19 0,000 0,02011472 0,03117183 ! SH2 domain binding GO:0042169 25 19 0,000 0,02011472 0,03115859 ! neurotransmitter:sodium symporter activity GO:0005328 21 19 0,000 0,02011472 0,03114537 ! negative regulation of protein catabolic process GO:0042177 19 19 0,000 0,02011472 0,03113215 ! carbohydrate kinase activity GO:0019200 20 19 0,000 0,02011472 0,03111895 ! RNA methyltransferase activity GO:0008173 19 19 0,000 0,02011472 0,03110576 ! RNA-dependent ATPase activity GO:0008186 29 19 0,000 0,02011472 0,03109258 ! body fluid secretion GO:0007589 21 19 0,000 0,02011472 0,03107941 ! neuropeptide hormone activity GO:0005184 25 19 0,000 0,02011472 0,03106625 ! secretory granule membrane GO:0030667 21 19 0,000 0,02011472 0,03105311 ! extracellular-glutamate-gated ion channel activity GO:0005234 23 19 0,000 0,02011472 0,03103997 ! ribonucleoprotein binding GO:0043021 20 19 0,000 0,02011472 0,03102685 ! peptidase activator activity GO:0016504 21 19 0,000 0,02011472 0,03101373 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,02011472 0,03100063 ! small conjugating protein-specific protease activity GO:0019783 21 19 0,000 0,02011472 0,03098754 ! regulation of BMP signaling pathway GO:0030510 20 19 0,000 0,02011472 0,03097446 ! sialyltransferase activity GO:0008373 31 19 0,000 0,02011472 0,03096139 ! ATP-dependent DNA helicase activity GO:0004003 30 19 0,000 0,02011472 0,03094833 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 23 20 0,000 0,02116267 0,03254697 ! regulation of anti-apoptosis GO:0045767 20 20 0,000 0,02116267 0,03253325 ! reciprocal meiotic recombination GO:0007131 40 20 0,000 0,02116267 0,03251955 ! protein amino acid ADP-ribosylation GO:0006471 23 20 0,000 0,02116267 0,03250586 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 30 20 0,000 0,02116267 0,03249218 ! retina development in camera-type eye GO:0060041 24 20 0,000 0,02116267 0,03247851 ! negative regulation of lipid metabolic process GO:0045833 34 20 0,000 0,02116267 0,03246485 ! ovarian follicle development GO:0001541 21 20 0,000 0,02116267 0,0324512 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 33 20 0,000 0,02116267 0,03243757 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 21 20 0,000 0,02116267 0,03242394 ! hydrogen peroxide metabolic process GO:0042743 20 20 0,000 0,02116267 0,03241033 ! diencephalon development GO:0021536 22 20 0,000 0,02116267 0,03239673 ! nuclear inner membrane GO:0005637 21 20 0,000 0,02116267 0,03238314 ! regulation of lipid transport GO:0032368 22 20 0,000 0,02116267 0,03236956 ! response to glucocorticoid stimulus GO:0051384 22 20 0,000 0,02116267 0,032356 ! glutathione metabolic process GO:0006749 21 20 0,000 0,02116267 0,03234244 ! transcriptional repressor complex GO:0017053 23 20 0,000 0,02116267 0,0323289 ! vitamin A metabolic process GO:0006776 20 20 0,000 0,02116267 0,03231537 ! positive regulation of lymphocyte differentiation GO:0045621 30 20 0,000 0,02116267 0,03230184 ! negative regulation of cytokine production GO:0001818 23 20 0,000 0,02116267 0,03228834 ! phosphorus-oxygen lyase activity GO:0016849 21 20 0,000 0,02116267 0,03227484 ! peptide hormone secretion GO:0030072 25 20 0,000 0,02116267 0,03226135 GO:0002790|peptide secretion, ! actin filament-based movement GO:0030048 22 20 0,000 0,02116267 0,03224787 ! Rab GTPase binding GO:0017137 22 20 0,000 0,02116267 0,03223441 ! initiation of viral infection GO:0019059 22 20 0,000 0,02116267 0,03222096 ! voltage-gated anion channel activity GO:0008308 23 20 0,000 0,02116267 0,03220751 ! heterochromatin GO:0000792 20 20 0,000 0,02116267 0,03219408 ! aminoglycan catabolic process GO:0006026 22 20 0,000 0,02116267 0,03218066 ! glycosaminoglycan biosynthetic process GO:0006024 21 20 0,000 0,02116267 0,03216725 ! regulation of chemotaxis GO:0050920 22 20 0,000 0,02116267 0,03215386 ! calcium-independent cell-cell adhesion GO:0016338 27 20 0,000 0,02116267 0,03214047 ! high-density lipoprotein particle GO:0034364 30 20 0,000 0,02116267 0,03212709 ! visual behavior GO:0007632 34 20 0,000 0,02116267 0,03211373 ! regulation of cell-matrix adhesion GO:0001952 26 20 0,000 0,02116267 0,03210038 GO:0010810|regulation of cell-substrate adhesion, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 23 20 0,000 0,02116267 0,03208704 ! immune response-activating cell surface receptor signaling pathway GO:0002429 27 20 0,000 0,02116267 0,03207371 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! vesicle docking during exocytosis GO:0006904 21 20 0,000 0,02116267 0,03206039 ! cell structure disassembly during apoptosis GO:0006921 31 20 0,000 0,02116267 0,03204708 ! nucleotide kinase activity GO:0019201 26 20 0,000 0,02116267 0,03203378 ! rRNA binding GO:0019843 22 20 0,000 0,02116267 0,03202049 ! cytolysis GO:0019835 22 20 0,000 0,02116267 0,03200722 ! renal system process GO:0003014 22 20 0,000 0,02116267 0,03199395 ! specific transcriptional repressor activity GO:0016566 23 20 0,000 0,02116267 0,0319807 ! fatty acid transport GO:0015908 23 20 0,000 0,02116267 0,03196746 ! transaminase activity GO:0008483 22 20 0,000 0,02116267 0,03195423 ! activation of JUN kinase activity GO:0007257 22 20 0,000 0,02116267 0,031941 ! collagen catabolic process GO:0030574 21 20 0,000 0,02116267 0,0319278 ! microvillus GO:0005902 25 20 0,000 0,02116267 0,0319146 ! tumor necrosis factor receptor binding GO:0005164 22 20 0,000 0,02116267 0,03190141 ! connexon complex GO:0005922 23 20 0,000 0,02116267 0,03188823 ! positive regulation of DNA replication GO:0045740 27 21 0,000 0,02220955 0,03345188 ! positive regulation of protein catabolic process GO:0045732 23 21 0,000 0,02220955 0,03343807 ! translational initiation GO:0006413 21 21 0,000 0,02220955 0,03342428 ! NF-kappaB binding GO:0051059 31 21 0,000 0,02220955 0,03341049 ! heterotrimeric G-protein complex GO:0005834 23 21 0,000 0,02220955 0,03339672 ! positive regulation of bone remodeling GO:0046852 22 21 0,000 0,02220955 0,03338296 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 21 0,000 0,02220955 0,03336921 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! transition metal ion transmembrane transporter activity GO:0046915 25 21 0,000 0,02220955 0,03335547 ! glutathione transferase activity GO:0004364 21 21 0,000 0,02220955 0,03334175 ! voltage-gated calcium channel complex GO:0005891 28 21 0,000 0,02220955 0,03332803 ! glutamate signaling pathway GO:0007215 23 21 0,000 0,02220955 0,03331433 ! regeneration GO:0031099 24 21 0,000 0,02220955 0,03330063 ! apoptotic mitochondrial changes GO:0008637 33 21 0,000 0,02220955 0,03328695 ! MHC class I protein complex GO:0042612 31 21 0,000 0,02220955 0,03327328 ! cellular response to starvation GO:0009267 22 21 0,000 0,02220955 0,03325962 ! peroxisome organization GO:0007031 22 21 0,000 0,02220955 0,03324598 ! vacuole organization GO:0007033 23 21 0,000 0,02220955 0,03323234 ! apoptotic nuclear changes GO:0030262 24 21 0,000 0,02220955 0,03321871 ! response to lipopolysaccharide GO:0032496 31 21 0,000 0,02220955 0,0332051 ! neural crest cell development GO:0014032 24 21 0,000 0,02220955 0,0331915 GO:0014033|neural crest cell differentiation, ! regulation of protein binding GO:0043393 25 21 0,000 0,02220955 0,03317791 ! nucleobase metabolic process GO:0009112 23 21 0,000 0,02220955 0,03316432 ! regulation of steroid metabolic process GO:0019218 23 21 0,000 0,02220955 0,03315075 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,02220955 0,0331372 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! monocarboxylic acid transmembrane transporter activity GO:0008028 25 21 0,000 0,02220955 0,03312365 ! pallium development GO:0021543 22 21 0,000 0,02220955 0,03311011 ! synaptic vesicle transport GO:0048489 25 21 0,000 0,02220955 0,03309659 ! negative regulation of Wnt receptor signaling pathway GO:0030178 22 21 0,000 0,02220955 0,03308307 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 21 0,000 0,02220955 0,03306957 ! leukocyte homeostasis GO:0001776 22 21 0,000 0,02220955 0,03305608 ! negative regulation of neuron differentiation GO:0045665 22 21 0,000 0,02220955 0,0330426 ! cyclase activity GO:0009975 22 21 0,000 0,02220955 0,03302913 ! aspartate family amino acid metabolic process GO:0009066 24 21 0,000 0,02220955 0,03301567 ! gut development GO:0048565 23 21 0,000 0,02220955 0,03300222 ! calcium-dependent phospholipid binding GO:0005544 22 21 0,000 0,02220955 0,03298878 ! negative regulation of T cell activation GO:0050868 23 21 0,000 0,02220955 0,03297535 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,02220955 0,03296194 ! cortical actin cytoskeleton GO:0030864 21 21 0,000 0,02220955 0,03294853 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,02220955 0,03293514 ! membrane lipid biosynthetic process GO:0046467 22 21 0,000 0,02220955 0,03292176 ! nucleotide-excision repair, DNA damage removal GO:0000718 22 21 0,000 0,02220955 0,03290839 ! axis specification GO:0009798 25 21 0,000 0,02220955 0,03289502 ! response to alkaloid GO:0043279 27 21 0,000 0,02220955 0,03288167 ! 4 iron, 4 sulfur cluster binding GO:0051539 24 21 0,000 0,02220955 0,03286833 ! response to ethanol GO:0045471 28 21 0,000 0,02220955 0,03285501 ! response to carbohydrate stimulus GO:0009743 24 21 0,000 0,02220955 0,03284169 ! smooth muscle contraction GO:0006939 25 21 0,000 0,02220955 0,03282838 ! ubiquitin binding GO:0043130 25 21 0,000 0,02220955 0,03281509 ! vesicle targeting GO:0006903 22 21 0,000 0,02220955 0,0328018 ! phospholipase A2 activity GO:0004623 32 21 0,000 0,02220955 0,03278852 ! SNARE binding GO:0000149 24 21 0,000 0,02220955 0,03277526 ! interaction with host GO:0051701 26 21 0,000 0,02220955 0,03276201 ! positive regulation of myeloid leukocyte differentiation GO:0002763 26 21 0,000 0,02220955 0,03274877 ! lymphocyte proliferation GO:0046651 24 21 0,000 0,02220955 0,03273553 ! regulation of tumor necrosis factor production GO:0032680 24 21 0,000 0,02220955 0,03272231 ! regulation of interleukin-2 production GO:0032663 21 21 0,000 0,02220955 0,0327091 ! negative regulation of angiogenesis GO:0016525 23 21 0,000 0,02220955 0,0326959 ! cell-cell junction organization GO:0045216 24 21 0,000 0,02220955 0,03268271 ! single-stranded RNA binding GO:0003727 22 21 0,000 0,02220955 0,03266953 ! cyclic nucleotide binding GO:0030551 25 21 0,000 0,02220955 0,03265637 ! caveola GO:0005901 25 21 0,000 0,02220955 0,03264321 ! water-soluble vitamin biosynthetic process GO:0042364 23 21 0,000 0,02220955 0,03263006 ! insulin receptor binding GO:0005158 25 21 0,000 0,02220955 0,03261693 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,02220955 0,0326038 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,02220955 0,03259069 ! mRNA export from nucleus GO:0006406 26 22 0,000 0,02325537 0,03411162 ! metencephalon development GO:0022037 25 22 0,000 0,02325537 0,03409791 ! regulation of interferon-gamma production GO:0032649 25 22 0,000 0,02325537 0,03408421 ! hormone secretion GO:0046879 28 22 0,000 0,02325537 0,03407052 ! vesicle docking GO:0048278 24 22 0,000 0,02325537 0,03405684 ! muscle myosin complex GO:0005859 23 22 0,000 0,02325537 0,03404318 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 24 22 0,000 0,02325537 0,03402952 ! actomyosin structure organization GO:0031032 24 22 0,000 0,02325537 0,03401588 ! microtubule organizing center organization GO:0031023 33 22 0,000 0,02325537 0,03400224 GO:0051297|centrosome organization, ! positive regulation of innate immune response GO:0045089 23 22 0,000 0,02325537 0,03398862 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 33 22 0,000 0,02325537 0,03397501 ! sperm motility GO:0030317 23 22 0,000 0,02325537 0,03396141 ! potassium channel regulator activity GO:0015459 29 22 0,000 0,02325537 0,03394782 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 24 22 0,000 0,02325537 0,03393424 ! vacuolar transport GO:0007034 22 22 0,000 0,02325537 0,03392067 ! oxidoreductase activity, acting on heme group of donors GO:0016675 23 22 0,000 0,02325537 0,03390711 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! central nervous system neuron differentiation GO:0021953 24 22 0,000 0,02325537 0,03389357 ! cellular response to reactive oxygen species GO:0034614 26 22 0,000 0,02325537 0,03388003 ! purine ribonucleoside metabolic process GO:0046128 24 22 0,000 0,02325537 0,03386651 GO:0042278|purine nucleoside metabolic process, ! G-protein chemoattractant receptor activity GO:0001637 24 22 0,000 0,02325537 0,03385299 GO:0004950|chemokine receptor activity, ! response to corticosteroid stimulus GO:0031960 25 22 0,000 0,02325537 0,03383949 ! PML body GO:0016605 25 22 0,000 0,02325537 0,033826 ! barbed-end actin filament capping GO:0051016 24 22 0,000 0,02325537 0,03381252 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 27 22 0,000 0,02325537 0,03379904 ! regulation of foam cell differentiation GO:0010743 28 22 0,000 0,02325537 0,03378558 ! cyclic nucleotide biosynthetic process GO:0009190 23 22 0,000 0,02325537 0,03377213 ! leukotriene metabolic process GO:0006691 23 22 0,000 0,02325537 0,03375869 ! glycosphingolipid metabolic process GO:0006687 23 22 0,000 0,02325537 0,03374527 ! deacetylase activity GO:0019213 23 22 0,000 0,02325537 0,03373185 ! pentose metabolic process GO:0019321 23 22 0,000 0,02325537 0,03371844 ! collagen fibril organization GO:0030199 32 22 0,000 0,02325537 0,03370505 ! regulation of response to biotic stimulus GO:0002831 33 22 0,000 0,02325537 0,03369166 ! positive regulation of adaptive immune response GO:0002821 22 22 0,000 0,02325537 0,03367829 ! peptidyl-serine modification GO:0018209 30 22 0,000 0,02325537 0,03366492 ! DNA-directed RNA polymerase complex GO:0000428 23 22 0,000 0,02325537 0,03365157 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! positive regulation of B cell activation GO:0050871 26 22 0,000 0,02325537 0,03363822 ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 32 22 0,000 0,02325537 0,03362489 ! positive regulation of behavior GO:0048520 24 22 0,000 0,02325537 0,03361157 ! regulation of generation of precursor metabolites and energy GO:0043467 25 22 0,000 0,02325537 0,03359826 ! aromatic compound catabolic process GO:0019439 23 22 0,000 0,02325537 0,03358496 ! embryonic epithelial tube formation GO:0001838 25 22 0,000 0,02325537 0,03357167 GO:0001841|neural tube formation, ! telomere organization GO:0032200 43 22 0,000 0,02325537 0,03355839 GO:0000723|telomere maintenance, ! acetyl-CoA catabolic process GO:0046356 24 22 0,000 0,02325537 0,03354512 GO:0006099|tricarboxylic acid cycle, ! protein tetramerization GO:0051262 25 22 0,000 0,02325537 0,03353186 ! DNA catabolic process, endonucleolytic GO:0000737 24 22 0,000 0,02325537 0,03351861 ! glycerol metabolic process GO:0006071 24 22 0,000 0,02325537 0,03350537 ! cellular component assembly involved in morphogenesis GO:0010927 23 22 0,000 0,02325537 0,03349214 ! nuclear chromatin GO:0000790 23 22 0,000 0,02325537 0,03347893 ! cellular iron ion homeostasis GO:0006879 25 22 0,000 0,02325537 0,03346572 ! aminoglycan biosynthetic process GO:0006023 23 22 0,000 0,02325537 0,03345252 ! positive regulation of JAK-STAT cascade GO:0046427 25 22 0,000 0,02325537 0,03343934 ! sterol binding GO:0032934 24 22 0,000 0,02325537 0,03342616 ! calcium-dependent cell-cell adhesion GO:0016339 23 22 0,000 0,02325537 0,033413 ! digestive system process GO:0022600 25 22 0,000 0,02325537 0,03339984 ! neurotransmitter transporter activity GO:0005326 24 22 0,000 0,02325537 0,0333867 ! organic acid:sodium symporter activity GO:0005343 25 22 0,000 0,02325537 0,03337356 ! nonmotile primary cilium GO:0031513 24 22 0,000 0,02325537 0,03336044 ! negative regulation of myeloid leukocyte differentiation GO:0002762 26 22 0,000 0,02325537 0,03334733 ! base-excision repair GO:0006284 33 22 0,000 0,02325537 0,03333422 ! regulation of chromosome organization GO:0033044 27 22 0,000 0,02325537 0,03332113 ! DNA modification GO:0006304 25 22 0,000 0,02325537 0,03330805 ! detection of chemical stimulus GO:0009593 23 22 0,000 0,02325537 0,03329498 ! positive regulation of tissue remodeling GO:0034105 23 22 0,000 0,02325537 0,03328191 ! GABA-A receptor activity GO:0004890 27 22 0,000 0,02325537 0,03326886 ! response to cytokine stimulus GO:0034097 25 22 0,000 0,02325537 0,03325582 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 24 22 0,000 0,02325537 0,03324279 ! pyrimidine nucleoside metabolic process GO:0006213 27 22 0,000 0,02325537 0,03322977 ! phosphoprotein phosphatase inhibitor activity GO:0004864 25 22 0,000 0,02325537 0,03321676 ! solute:cation antiporter activity GO:0015298 23 22 0,000 0,02325537 0,03320376 ! regulation of transmembrane transport GO:0034762 28 23 0,000 0,02430013 0,03468188 ! protein amino acid O-linked glycosylation GO:0006493 28 23 0,000 0,02430013 0,03466831 ! leukocyte adhesion GO:0007159 26 23 0,000 0,02430013 0,03465476 ! dicarboxylic acid metabolic process GO:0043648 27 23 0,000 0,02430013 0,03464122 ! odontogenesis of dentine-containing tooth GO:0042475 26 23 0,000 0,02430013 0,03462769 ! positive regulation of endocytosis GO:0045807 25 23 0,000 0,02430013 0,03461417 ! ureteric bud development GO:0001657 24 23 0,000 0,02430013 0,03460066 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 27 23 0,000 0,02430013 0,03458716 ! regulation of insulin secretion GO:0050796 27 23 0,000 0,02430013 0,03457367 ! vitamin biosynthetic process GO:0009110 25 23 0,000 0,02430013 0,03456019 ! negative regulation of neurogenesis GO:0050768 29 23 0,000 0,02430013 0,03454672 ! cholesterol biosynthetic process GO:0006695 29 23 0,000 0,02430013 0,03453326 ! deaminase activity GO:0019239 24 23 0,000 0,02430013 0,03451981 ! sensory perception of pain GO:0019233 26 23 0,000 0,02430013 0,03450638 ! lipid kinase activity GO:0001727 26 23 0,000 0,02430013 0,03449295 ! platelet activation GO:0030168 27 23 0,000 0,02430013 0,03447953 ! proteoglycan biosynthetic process GO:0030166 24 23 0,000 0,02430013 0,03446613 ! positive regulation of intracellular transport GO:0032388 26 23 0,000 0,02430013 0,03445273 ! regulation of blood coagulation GO:0030193 26 23 0,000 0,02430013 0,03443935 ! regulation of cytokine secretion GO:0050707 27 23 0,000 0,02430013 0,03442597 ! fat-soluble vitamin metabolic process GO:0006775 23 23 0,000 0,02430013 0,03441261 ! cellular alkene metabolic process GO:0043449 24 23 0,000 0,02430013 0,03439925 ! aromatic amino acid family metabolic process GO:0009072 25 23 0,000 0,02430013 0,03438591 ! cell surface binding GO:0043498 28 23 0,000 0,02430013 0,03437258 ! porphyrin metabolic process GO:0006778 24 23 0,000 0,02430013 0,03435926 GO:0033013|tetrapyrrole metabolic process, ! ligase activity, forming carbon-sulfur bonds GO:0016877 24 23 0,000 0,02430013 0,03434594 ! regulation of glucose import GO:0046324 28 23 0,000 0,02430013 0,03433264 ! insulin-like growth factor binding GO:0005520 27 23 0,000 0,02430013 0,03431935 ! alditol metabolic process GO:0019400 25 23 0,000 0,02430013 0,03430607 ! positive regulation of JUN kinase activity GO:0043507 25 23 0,000 0,02430013 0,0342928 ! pyruvate metabolic process GO:0006090 27 23 0,000 0,02430013 0,03427954 ! zinc ion transport GO:0006829 26 23 0,000 0,02430013 0,03426628 ! N-acetylglucosamine metabolic process GO:0006044 26 23 0,000 0,02430013 0,03425304 ! antigen processing and presentation of peptide antigen GO:0048002 30 23 0,000 0,02430013 0,03423981 ! sex determination GO:0007530 25 23 0,000 0,02430013 0,03422659 ! phosphate binding GO:0042301 25 23 0,000 0,02430013 0,03421338 ! positive regulation of leukocyte mediated immunity GO:0002705 24 23 0,000 0,02430013 0,03420018 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of interleukin-6 production GO:0032675 26 23 0,000 0,02430013 0,034187 ! nuclear-transcribed mRNA catabolic process GO:0000956 26 23 0,000 0,02430013 0,03417382 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 28 23 0,000 0,02430013 0,03416065 ! ubiquitin protein ligase binding GO:0031625 24 23 0,000 0,02430013 0,03414749 ! synaptogenesis GO:0007416 25 23 0,000 0,02430013 0,03413434 ! regulation of bone mineralization GO:0030500 23 23 0,000 0,02430013 0,0341212 ! neurotransmitter secretion GO:0007269 26 23 0,000 0,02430013 0,03410807 ! ethanolamine and derivative metabolic process GO:0042439 34 23 0,000 0,02430013 0,03409495 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 25 23 0,000 0,02430013 0,03408185 ! leukocyte proliferation GO:0070661 26 23 0,000 0,02430013 0,03406875 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 24 23 0,000 0,02430013 0,03405566 ! growth cone GO:0030426 27 24 0,000 0,02534383 0,03550472 ! oligosaccharide metabolic process GO:0009311 29 24 0,000 0,02534383 0,03549109 ! actin filament GO:0005884 26 24 0,000 0,02534383 0,03547747 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,02534383 0,03546386 ! pancreas development GO:0031016 27 24 0,000 0,02534383 0,03545026 ! androgen receptor binding GO:0050681 34 24 0,000 0,02534383 0,03543667 ! calcium channel complex GO:0034704 31 24 0,000 0,02534383 0,0354231 ! coenzyme catabolic process GO:0009109 26 24 0,000 0,02534383 0,03540953 ! negative regulation of cell development GO:0010721 30 24 0,000 0,02534383 0,03539597 ! cardiac muscle tissue morphogenesis GO:0055008 27 24 0,000 0,02534383 0,03538243 GO:0060415|muscle tissue morphogenesis, ! phosphatase inhibitor activity GO:0019212 27 24 0,000 0,02534383 0,03536889 ! regulation of ARF GTPase activity GO:0032312 28 24 0,000 0,02534383 0,03535537 ! regulation of oxidoreductase activity GO:0051341 24 24 0,000 0,02534383 0,03534185 ! RNA splicing factor activity, transesterification mechanism GO:0031202 25 24 0,000 0,02534383 0,03532835 ! Rho GTPase binding GO:0017048 36 24 0,000 0,02534383 0,03531485 ! regulation of glucose transport GO:0010827 29 24 0,000 0,02534383 0,03530137 ! serine family amino acid metabolic process GO:0009069 27 24 0,000 0,02534383 0,03528789 ! intramolecular transferase activity GO:0016866 26 24 0,000 0,02534383 0,03527443 ! phosphoinositide phospholipase C activity GO:0004435 28 24 0,000 0,02534383 0,03526098 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! Z disc GO:0030018 27 24 0,000 0,02534383 0,03524754 ! protein stabilization GO:0050821 24 24 0,000 0,02534383 0,0352341 ! protein import into nucleus, translocation GO:0000060 27 24 0,000 0,02534383 0,03522068 ! embryonic pattern specification GO:0009880 29 24 0,000 0,02534383 0,03520727 ! negative regulation of actin filament depolymerization GO:0030835 26 24 0,000 0,02534383 0,03519387 ! RNA polymerase complex GO:0030880 25 24 0,000 0,02534383 0,03518047 ! cellular polysaccharide biosynthetic process GO:0033692 24 24 0,000 0,02534383 0,03516709 ! glucosamine metabolic process GO:0006041 27 24 0,000 0,02534383 0,03515372 ! small conjugating protein binding GO:0032182 29 24 0,000 0,02534383 0,03514036 ! regulation of transcription factor import into nucleus GO:0042990 26 24 0,000 0,02534383 0,03512701 ! chemokine binding GO:0019956 26 24 0,000 0,02534383 0,03511367 ! catechol metabolic process GO:0009712 29 24 0,000 0,02534383 0,03510034 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of smooth muscle contraction GO:0006940 28 24 0,000 0,02534383 0,03508702 ! NAD+ ADP-ribosyltransferase activity GO:0003950 26 24 0,000 0,02534383 0,0350737 ! multicellular organismal response to stress GO:0033555 27 24 0,000 0,02534383 0,0350604 ! cell aging GO:0007569 47 24 0,000 0,02534383 0,03504711 ! immune response-activating signal transduction GO:0002757 31 24 0,000 0,02534383 0,03503383 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 24 0,000 0,02534383 0,03502056 ! fibroblast growth factor receptor signaling pathway GO:0008543 27 24 0,000 0,02534383 0,0350073 ! voltage-gated calcium channel activity GO:0005245 31 24 0,000 0,02534383 0,03499405 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 29 24 0,000 0,02534383 0,03498081 ! metallocarboxypeptidase activity GO:0004181 24 24 0,000 0,02534383 0,03496758 ! regulation of microtubule cytoskeleton organization GO:0070507 35 24 0,000 0,02534383 0,03495436 ! 3'-5' exonuclease activity GO:0008408 43 24 0,000 0,02534383 0,03494115 ! small nuclear ribonucleoprotein complex GO:0030532 24 24 0,000 0,02534383 0,03492795 ! selenium binding GO:0008430 24 24 0,000 0,02534383 0,03491476 ! spindle pole GO:0000922 35 24 0,000 0,02534383 0,03490158 ! Rho GTPase activator activity GO:0005100 28 24 0,000 0,02534383 0,03488841 ! site of polarized growth GO:0030427 28 25 0,000 0,02638646 0,03631 ! phenol metabolic process GO:0018958 31 25 0,000 0,02638646 0,03629631 ! regulation of lipid biosynthetic process GO:0046890 35 25 0,000 0,02638646 0,03628263 ! protein amino acid acylation GO:0043543 28 25 0,000 0,02638646 0,03626896 ! aromatase activity GO:0070330 28 25 0,000 0,02638646 0,0362553 ! cholesterol homeostasis GO:0042632 27 25 0,000 0,02638646 0,03624165 GO:0055092|sterol homeostasis, ! positive regulation of epithelial cell proliferation GO:0050679 29 25 0,000 0,02638646 0,03622801 ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 29 25 0,000 0,02638646 0,03621438 ! response to starvation GO:0042594 26 25 0,000 0,02638646 0,03620076 ! dynein complex GO:0030286 28 25 0,000 0,02638646 0,03618715 ! ARF GTPase activator activity GO:0008060 29 25 0,000 0,02638646 0,03617355 ! regulation of behavior GO:0050795 27 25 0,000 0,02638646 0,03615996 ! regulation of biomineral formation GO:0070167 25 25 0,000 0,02638646 0,03614638 ! hexose biosynthetic process GO:0019319 31 25 0,000 0,02638646 0,03613282 ! group transfer coenzyme metabolic process GO:0006752 25 25 0,000 0,02638646 0,03611926 ! hormone transport GO:0009914 31 25 0,000 0,02638646 0,03610571 ! response to molecule of bacterial origin GO:0002237 35 25 0,000 0,02638646 0,03609217 ! cell adhesion molecule binding GO:0050839 29 25 0,000 0,02638646 0,03607864 ! regulation of coagulation GO:0050818 28 25 0,000 0,02638646 0,03606513 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,02638646 0,03605162 ! myeloid leukocyte differentiation GO:0002573 28 25 0,000 0,02638646 0,03603812 ! acetyl-CoA metabolic process GO:0006084 27 25 0,000 0,02638646 0,03602463 ! chromosome, telomeric region GO:0000781 38 25 0,000 0,02638646 0,03601116 ! molting cycle process GO:0022404 28 25 0,000 0,02638646 0,03599769 GO:0022405|hair cycle process, GO:0001942|hair follicle development, ! collagen metabolic process GO:0032963 26 25 0,000 0,02638646 0,03598423 ! xenobiotic metabolic process GO:0006805 27 25 0,000 0,02638646 0,03597079 ! phototransduction GO:0007602 27 25 0,000 0,02638646 0,03595735 ! negative regulation of response to external stimulus GO:0032102 30 25 0,000 0,02638646 0,03594392 ! regulation of endothelial cell proliferation GO:0001936 29 25 0,000 0,02638646 0,0359305 ! protein phosphatase binding GO:0019903 27 25 0,000 0,02638646 0,0359171 ! negative regulation of DNA replication GO:0008156 31 25 0,000 0,02638646 0,0359037 ! multicellular organismal catabolic process GO:0044243 27 25 0,000 0,02638646 0,03589031 ! autophagy GO:0006914 28 25 0,000 0,02638646 0,03587694 ! steroid dehydrogenase activity GO:0016229 27 25 0,000 0,02638646 0,03586357 ! response to ionizing radiation GO:0010212 37 25 0,000 0,02638646 0,03585021 ! DNA-directed DNA polymerase activity GO:0003887 30 25 0,000 0,02638646 0,03583687 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 31 26 0,000 0,02742804 0,03723762 ! positive regulation of cell adhesion GO:0045785 34 26 0,000 0,02742804 0,03722377 ! epidermal growth factor receptor signaling pathway GO:0007173 32 26 0,000 0,02742804 0,03720993 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 29 26 0,000 0,02742804 0,03719609 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 26 0,000 0,02742804 0,03718227 ! positive regulation of lipid metabolic process GO:0045834 27 26 0,000 0,02742804 0,03716846 ! hair cycle GO:0042633 29 26 0,000 0,02742804 0,03715466 GO:0042303|molting cycle, ! thyroid hormone receptor binding GO:0046966 30 26 0,000 0,02742804 0,03714087 ! polysaccharide catabolic process GO:0000272 39 26 0,000 0,02742804 0,03712708 ! peptidyl-tyrosine phosphorylation GO:0018108 30 26 0,000 0,02742804 0,03711331 ! early endosome membrane GO:0031901 31 26 0,000 0,02742804 0,03709955 ! negative regulation of protein kinase cascade GO:0010741 40 26 0,000 0,02742804 0,0370858 ! iron ion homeostasis GO:0055072 29 26 0,000 0,02742804 0,03707206 ! glycolipid metabolic process GO:0006664 36 26 0,000 0,02742804 0,03705833 ! GABA receptor activity GO:0016917 31 26 0,000 0,02742804 0,03704461 ! PDZ domain binding GO:0030165 28 26 0,000 0,02742804 0,0370309 ! positive regulation of protein secretion GO:0050714 29 26 0,000 0,02742804 0,0370172 ! regulation of cellular carbohydrate metabolic process GO:0010675 29 26 0,000 0,02742804 0,03700351 ! AP-type membrane coat adaptor complex GO:0030119 30 26 0,000 0,02742804 0,03698983 GO:0030131|clathrin adaptor complex, ! neuromuscular process controlling balance GO:0050885 32 26 0,000 0,02742804 0,03697616 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 45 26 0,000 0,02742804 0,0369625 ! fatty acid binding GO:0005504 28 26 0,000 0,02742804 0,03694885 ! blastocyst development GO:0001824 27 26 0,000 0,02742804 0,03693521 ! regulation of JUN kinase activity GO:0043506 28 26 0,000 0,02742804 0,03692158 ! lysine N-acetyltransferase activity GO:0004468 29 26 0,000 0,02742804 0,03690796 GO:0004402|histone acetyltransferase activity, ! negative regulation of protein polymerization GO:0032272 37 26 0,000 0,02742804 0,03689436 ! regulation of fibroblast proliferation GO:0048145 32 26 0,000 0,02742804 0,03688076 ! regulation of smooth muscle cell proliferation GO:0048660 30 26 0,000 0,02742804 0,03686717 ! regulation of actin filament depolymerization GO:0030834 28 26 0,000 0,02742804 0,03685359 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,02742804 0,03684002 ! iron ion transport GO:0006826 33 26 0,000 0,02742804 0,03682646 ! regulation of synaptic plasticity GO:0048167 36 26 0,000 0,02742804 0,03681291 ! glucose transport GO:0015758 27 26 0,000 0,02742804 0,03679937 ! insulin receptor signaling pathway GO:0008286 34 26 0,000 0,02742804 0,03678584 ! spinal cord development GO:0021510 30 26 0,000 0,02742804 0,03677232 ! histone deacetylase complex GO:0000118 29 26 0,000 0,02742804 0,03675881 ! regulation of peptide secretion GO:0002791 30 26 0,000 0,02742804 0,03674531 ! regulation of production of molecular mediator of immune response GO:0002700 27 26 0,000 0,02742804 0,03673183 ! RNA helicase activity GO:0003724 46 26 0,000 0,02742804 0,03671835 ! brush border GO:0005903 30 26 0,000 0,02742804 0,03670488 ! gap junction GO:0005921 29 26 0,000 0,02742804 0,03669142 ! anion:cation symporter activity GO:0015296 29 26 0,000 0,02742804 0,03667797 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 39 27 0,000 0,02846856 0,03805544 ! RNA export from nucleus GO:0006405 31 27 0,000 0,02846856 0,0380415 ! mRNA catabolic process GO:0006402 31 27 0,000 0,02846856 0,03802757 ! myelination GO:0042552 31 27 0,000 0,02846856 0,03801365 ! trans-Golgi network GO:0005802 31 27 0,000 0,02846856 0,03799974 ! transferase activity, transferring nitrogenous groups GO:0016769 29 27 0,000 0,02846856 0,03798585 ! spliceosomal snRNP biogenesis GO:0000387 29 27 0,000 0,02846856 0,03797196 ! solute:solute antiporter activity GO:0015300 28 27 0,000 0,02846856 0,03795808 ! vasculogenesis GO:0001570 32 27 0,000 0,02846856 0,03794421 ! hexose transport GO:0008645 28 27 0,000 0,02846856 0,03793035 GO:0015749|monosaccharide transport, ! regulation of innate immune response GO:0045088 28 27 0,000 0,02846856 0,0379165 ! spindle organization GO:0007051 38 27 0,000 0,02846856 0,03790266 ! cellular response to oxidative stress GO:0034599 32 27 0,000 0,02846856 0,03788884 ! response to organic cyclic substance GO:0014070 34 27 0,000 0,02846856 0,03787502 ! cell fate determination GO:0001709 29 27 0,000 0,02846856 0,03786121 ! lipid oxidation GO:0034440 29 27 0,000 0,02846856 0,03784741 GO:0019395|fatty acid oxidation, ! fatty acid catabolic process GO:0009062 31 27 0,000 0,02846856 0,03783362 ! carboxy-lyase activity GO:0016831 27 27 0,000 0,02846856 0,03781985 ! phospholipid transporter activity GO:0005548 30 27 0,000 0,02846856 0,03780608 ! liver development GO:0001889 33 27 0,000 0,02846856 0,03779232 ! mitotic sister chromatid segregation GO:0000070 46 27 0,000 0,02846856 0,03777857 ! determination of bilateral symmetry GO:0009855 32 27 0,000 0,02846856 0,03776484 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! integrin complex GO:0008305 30 27 0,000 0,02846856 0,03775111 ! membrane docking GO:0022406 29 27 0,000 0,02846856 0,03773739 ! detection of light stimulus involved in sensory perception GO:0050962 29 27 0,000 0,02846856 0,03772368 GO:0050908|detection of light stimulus involved in visual perception, ! multicellular organismal macromolecule metabolic process GO:0044259 28 27 0,000 0,02846856 0,03770999 ! respiratory gaseous exchange GO:0007585 30 27 0,000 0,02846856 0,0376963 ! phospholipid transport GO:0015914 29 27 0,000 0,02846856 0,03768262 ! sarcoplasmic reticulum GO:0016529 29 27 0,000 0,02846856 0,03766895 ! aminopeptidase activity GO:0004177 33 27 0,000 0,02846856 0,03765529 ! cellular response to nutrient levels GO:0031669 28 27 0,000 0,02846856 0,03764165 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 33 27 0,000 0,02846856 0,03762801 ! biogenic amine biosynthetic process GO:0042401 29 27 0,000 0,02846856 0,03761438 ! negative regulation of transcription regulator activity GO:0090048 32 27 0,000 0,02846856 0,03760076 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 29 27 0,000 0,02846856 0,03758715 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 31 28 0,000 0,02950802 0,03894546 ! Golgi stack GO:0005795 30 28 0,000 0,02950802 0,03893137 ! male gonad development GO:0008584 32 28 0,000 0,02950802 0,0389173 ! regulation of fatty acid metabolic process GO:0019217 41 28 0,000 0,02950802 0,03890323 ! lipoprotein binding GO:0008034 31 28 0,000 0,02950802 0,03888918 ! mesoderm formation GO:0001707 34 28 0,000 0,02950802 0,03887514 ! negative regulation of MAP kinase activity GO:0043407 30 28 0,000 0,02950802 0,0388611 ! peptidyl-tyrosine modification GO:0018212 32 28 0,000 0,02950802 0,03884708 ! deoxyribonuclease activity GO:0004536 56 28 0,000 0,02950802 0,03883306 ! nicotinamide metabolic process GO:0006769 32 28 0,000 0,02950802 0,03881906 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 31 28 0,000 0,02950802 0,03880507 ! regulation of osteoblast differentiation GO:0045667 33 28 0,000 0,02950802 0,03879108 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 30 28 0,000 0,02950802 0,03877711 ! negative regulation of neuron apoptosis GO:0043524 39 28 0,000 0,02950802 0,03876314 ! tissue homeostasis GO:0001894 31 28 0,000 0,02950802 0,03874919 GO:0048871|multicellular organismal homeostasis, ! DNA damage checkpoint GO:0000077 48 28 0,000 0,02950802 0,03873525 ! negative regulation of protein complex assembly GO:0031333 39 28 0,000 0,02950802 0,03872131 ! regulation of carbohydrate metabolic process GO:0006109 31 28 0,000 0,02950802 0,03870739 ! sister chromatid segregation GO:0000819 49 28 0,000 0,02950802 0,03869348 ! post-embryonic development GO:0009791 32 28 0,000 0,02950802 0,03867957 ! complement activation, classical pathway GO:0006958 33 28 0,000 0,02950802 0,03866568 ! negative regulation of phosphorylation GO:0042326 30 28 0,000 0,02950802 0,0386518 ! detection of visible light GO:0009584 30 28 0,000 0,02950802 0,03863792 ! calcium-mediated signaling GO:0019722 30 28 0,000 0,02950802 0,03862406 ! receptor regulator activity GO:0030545 31 28 0,000 0,02950802 0,0386102 ! acetylgalactosaminyltransferase activity GO:0008376 33 28 0,000 0,02950802 0,03859636 ! symbiosis, encompassing mutualism through parasitism GO:0044403 33 28 0,000 0,02950802 0,03858253 ! response to heat GO:0009408 33 28 0,000 0,02950802 0,0385687 ! response to xenobiotic stimulus GO:0009410 31 28 0,000 0,02950802 0,03855489 ! response to hydrogen peroxide GO:0042542 32 29 0,000 0,03054642 0,03989737 ! hormone binding GO:0042562 31 29 0,000 0,03054642 0,03988309 ! establishment or maintenance of cell polarity GO:0007163 34 29 0,000 0,03054642 0,03986882 ! striated muscle cell differentiation GO:0051146 42 29 0,000 0,03054642 0,03985456 ! NADP or NADPH binding GO:0050661 33 29 0,000 0,03054642 0,03984031 ! nucleotide receptor activity, G-protein coupled GO:0001608 31 29 0,000 0,03054642 0,03982607 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 41 29 0,000 0,03054642 0,03981184 ! erythrocyte differentiation GO:0030218 35 29 0,000 0,03054642 0,03979762 ! ceramide metabolic process GO:0006672 29 29 0,000 0,03054642 0,03978342 ! replication fork GO:0005657 42 29 0,000 0,03054642 0,03976922 ! camera-type eye morphogenesis GO:0048593 36 29 0,000 0,03054642 0,03975503 ! monosaccharide biosynthetic process GO:0046364 35 29 0,000 0,03054642 0,03974085 ! negative regulation of lymphocyte activation GO:0051250 32 29 0,000 0,03054642 0,03972668 ! alkaloid metabolic process GO:0009820 33 29 0,000 0,03054642 0,03971253 ! icosanoid biosynthetic process GO:0046456 30 29 0,000 0,03054642 0,03969838 ! regulation of pH GO:0006885 30 29 0,000 0,03054642 0,03968424 ! amino sugar metabolic process GO:0006040 41 29 0,000 0,03054642 0,03967011 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 34 29 0,000 0,03054642 0,039656 ! phospholipase C activity GO:0004629 43 29 0,000 0,03054642 0,03964189 ! response to mechanical stimulus GO:0009612 33 29 0,000 0,03054642 0,03962779 ! clathrin coated vesicle membrane GO:0030665 33 29 0,000 0,03054642 0,0396137 ! sodium channel activity GO:0005272 33 29 0,000 0,03054642 0,03959963 ! sarcoplasm GO:0016528 31 29 0,000 0,03054642 0,03958556 ! detection of light stimulus GO:0009583 31 29 0,000 0,03054642 0,0395715 ! spermatid development GO:0007286 30 29 0,000 0,03054642 0,03955745 ! DNA polymerase activity GO:0034061 34 29 0,000 0,03054642 0,03954342 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 31 29 0,000 0,03054642 0,03952939 ! sarcolemma GO:0042383 30 29 0,000 0,03054642 0,03951537 ! tumor necrosis factor receptor superfamily binding GO:0032813 31 29 0,000 0,03054642 0,03950136 ! galactosyltransferase activity GO:0008378 33 29 0,000 0,03054642 0,03948737 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,03054642 0,03947338 ! transforming growth factor beta receptor signaling pathway GO:0007179 34 30 0,000 0,03158377 0,04079943 ! mitochondrial nucleoid GO:0042645 44 30 0,000 0,03158377 0,04078499 GO:0009295|nucleoid, ! cholesterol transport GO:0030301 33 30 0,000 0,03158377 0,04077056 GO:0015918|sterol transport, ! histone-lysine N-methyltransferase activity GO:0018024 34 30 0,000 0,03158377 0,04075613 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! cellular carbohydrate biosynthetic process GO:0034637 30 30 0,000 0,03158377 0,04074172 ! scavenger receptor activity GO:0005044 39 30 0,000 0,03158377 0,04072732 ! spliceosome assembly GO:0000245 34 30 0,000 0,03158377 0,04071293 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 39 30 0,000 0,03158377 0,04069855 GO:0004601|peroxidase activity, ! mesoderm morphogenesis GO:0048332 37 30 0,000 0,03158377 0,04068418 ! metanephros development GO:0001656 31 30 0,000 0,03158377 0,04066982 ! glutamate receptor activity GO:0008066 35 30 0,000 0,03158377 0,04065547 ! cyclic nucleotide metabolic process GO:0009187 31 30 0,000 0,03158377 0,04064113 ! positive regulation of MAPKKK cascade GO:0043410 36 30 0,000 0,03158377 0,0406268 ! regulation of macrophage differentiation GO:0045649 37 30 0,000 0,03158377 0,04061248 ! positive regulation of myeloid cell differentiation GO:0045639 37 30 0,000 0,03158377 0,04059817 ! negative regulation of myeloid cell differentiation GO:0045638 35 30 0,000 0,03158377 0,04058387 ! cis-trans isomerase activity GO:0016859 32 30 0,000 0,03158377 0,04056957 ! myeloid leukocyte activation GO:0002274 36 30 0,000 0,03158377 0,04055529 ! negative regulation of protein transport GO:0051224 34 30 0,000 0,03158377 0,04054102 ! condensed nuclear chromosome GO:0000794 31 30 0,000 0,03158377 0,04052676 ! cortical cytoskeleton GO:0030863 33 30 0,000 0,03158377 0,04051252 ! protein-lipid complex GO:0032994 41 30 0,000 0,03158377 0,04049828 GO:0034358|plasma lipoprotein particle, ! circadian rhythm GO:0007623 37 30 0,000 0,03158377 0,04048405 ! negative regulation of protein modification process GO:0031400 34 30 0,000 0,03158377 0,04046983 ! phosphatase binding GO:0019902 34 30 0,000 0,03158377 0,04045562 ! segmentation GO:0035282 37 30 0,000 0,03158377 0,04044142 ! response to toxin GO:0009636 33 30 0,000 0,03158377 0,04042723 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,03158377 0,04041305 ! antigen binding GO:0003823 33 30 0,000 0,03158377 0,04039888 ! regulation of systemic arterial blood pressure GO:0003073 33 30 0,000 0,03158377 0,04038472 ! Golgi-associated vesicle membrane GO:0030660 37 30 0,000 0,03158377 0,04037057 ! ensheathment of neurons GO:0007272 35 30 0,000 0,03158377 0,04035642 GO:0008366|axon ensheathment, ! JAK-STAT cascade GO:0007259 43 30 0,000 0,03158377 0,04034229 ! regulation of microtubule-based process GO:0032886 41 30 0,000 0,03158377 0,04032817 ! vesicle localization GO:0051648 31 30 0,000 0,03158377 0,04031406 ! negative regulation of cell adhesion GO:0007162 34 31 0,000 0,03262006 0,04162224 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,03262006 0,04160769 ! negative regulation of phosphorus metabolic process GO:0010563 34 31 0,000 0,03262006 0,04159315 GO:0045936|negative regulation of phosphate metabolic process, ! acrosomal vesicle GO:0001669 34 31 0,000 0,03262006 0,04157861 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,03262006 0,04156409 ! protein targeting to membrane GO:0006612 35 31 0,000 0,03262006 0,04154958 ! regulation of axonogenesis GO:0050770 37 31 0,000 0,03262006 0,04153508 ! regulation of T cell differentiation GO:0045580 43 31 0,000 0,03262006 0,04152058 ! formation of primary germ layer GO:0001704 37 31 0,000 0,03262006 0,0415061 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 33 31 0,000 0,03262006 0,04149163 ! endocytic vesicle GO:0030139 33 31 0,000 0,03262006 0,04147717 ! pyridine nucleotide metabolic process GO:0019362 35 31 0,000 0,03262006 0,04146271 ! spermatid differentiation GO:0048515 32 31 0,000 0,03262006 0,04144827 ! negative regulation of catabolic process GO:0009895 34 31 0,000 0,03262006 0,04143384 ! neuron fate commitment GO:0048663 44 31 0,000 0,03262006 0,04141942 ! regulation of cellular catabolic process GO:0031329 35 31 0,000 0,03262006 0,04140501 ! regulation of JAK-STAT cascade GO:0046425 37 31 0,000 0,03262006 0,04139061 ! morphogenesis of embryonic epithelium GO:0016331 36 31 0,000 0,03262006 0,04137621 ! macromolecular complex disassembly GO:0032984 37 31 0,000 0,03262006 0,04136183 ! cell junction assembly GO:0034329 36 31 0,000 0,03262006 0,04134746 ! drug binding GO:0008144 34 31 0,000 0,03262006 0,0413331 ! positive regulation of T cell proliferation GO:0042102 38 31 0,000 0,03262006 0,04131875 ! peptide transport GO:0015833 36 31 0,000 0,03262006 0,04130441 ! DNA integrity checkpoint GO:0031570 51 31 0,000 0,03262006 0,04129007 ! peripheral nervous system development GO:0007422 35 31 0,000 0,03262006 0,04127575 ! I band GO:0031674 34 31 0,000 0,03262006 0,04126144 ! BMP signaling pathway GO:0030509 33 31 0,000 0,03262006 0,04124714 ! adult locomotory behavior GO:0008344 37 31 0,000 0,03262006 0,04123285 ! gene silencing GO:0016458 33 31 0,000 0,03262006 0,04121856 ! negative regulation of adenylate cyclase activity GO:0007194 39 32 0,000 0,0336553 0,04251196 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of secretion GO:0051048 37 32 0,000 0,0336553 0,04249725 ! negative regulation of DNA metabolic process GO:0051053 38 32 0,000 0,0336553 0,04248254 ! phosphotransferase activity, phosphate group as acceptor GO:0016776 49 32 0,000 0,0336553 0,04246785 ! meiosis I GO:0007127 53 32 0,000 0,0336553 0,04245316 ! GPI anchor biosynthetic process GO:0006506 35 32 0,000 0,0336553 0,04243849 GO:0006505|GPI anchor metabolic process, ! unsaturated fatty acid biosynthetic process GO:0006636 33 32 0,000 0,0336553 0,04242382 ! sterol biosynthetic process GO:0016126 40 32 0,000 0,0336553 0,04240917 ! vesicle coat GO:0030120 39 32 0,000 0,0336553 0,04239453 ! cytokine production GO:0001816 32 32 0,000 0,0336553 0,04237989 ! regulation of calcium ion transport GO:0051924 37 32 0,000 0,0336553 0,04236527 ! proteoglycan metabolic process GO:0006029 34 32 0,000 0,0336553 0,04235065 ! sphingoid metabolic process GO:0046519 33 32 0,000 0,0336553 0,04233605 ! multicellular organismal metabolic process GO:0044236 35 32 0,000 0,0336553 0,04232146 ! oxygen binding GO:0019825 33 32 0,000 0,0336553 0,04230687 ! leukocyte chemotaxis GO:0030595 32 32 0,000 0,0336553 0,0422923 GO:0060326|cell chemotaxis, ! negative regulation of leukocyte activation GO:0002695 35 32 0,000 0,0336553 0,04227774 ! hormone biosynthetic process GO:0042446 32 32 0,000 0,0336553 0,04226318 ! double-stranded RNA binding GO:0003725 35 32 0,000 0,0336553 0,04224864 ! DNA helicase activity GO:0003678 55 33 0,000 0,03468949 0,04353191 ! neural tube development GO:0021915 37 33 0,000 0,03468949 0,04351694 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 33 0,000 0,03468949 0,04350198 ! pigment biosynthetic process GO:0046148 35 33 0,000 0,03468949 0,04348703 ! organelle envelope lumen GO:0031970 46 33 0,000 0,03468949 0,04347209 ! regulation of cellular ketone metabolic process GO:0010565 46 33 0,000 0,03468949 0,04345716 ! negative regulation of DNA binding GO:0043392 39 33 0,000 0,03468949 0,04344225 ! NAD or NADH binding GO:0051287 36 33 0,000 0,03468949 0,04342734 ! nucleotide catabolic process GO:0009166 35 33 0,000 0,03468949 0,04341244 ! B cell differentiation GO:0030183 37 33 0,000 0,03468949 0,04339755 ! regulation of Wnt receptor signaling pathway GO:0030111 36 33 0,000 0,03468949 0,04338267 ! aerobic respiration GO:0009060 35 33 0,000 0,03468949 0,04336781 ! embryonic organ development GO:0048568 41 33 0,000 0,03468949 0,04335295 ! placenta development GO:0001890 39 33 0,000 0,03468949 0,0433381 ! protein serine/threonine phosphatase complex GO:0008287 37 33 0,000 0,03468949 0,04332327 ! tissue remodeling GO:0048771 37 33 0,000 0,03468949 0,04330844 ! flagellum GO:0019861 34 33 0,000 0,03468949 0,04329362 ! L-amino acid transmembrane transporter activity GO:0015179 37 33 0,000 0,03468949 0,04327882 ! Rho protein signal transduction GO:0007266 35 33 0,000 0,03468949 0,04326402 ! odontogenesis GO:0042476 39 34 0,000 0,03572263 0,0445373 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,03572263 0,04452208 ! lipid homeostasis GO:0055088 37 34 0,000 0,03572263 0,04450688 ! telencephalon development GO:0021537 36 34 0,000 0,03572263 0,04449168 ! clathrin coat GO:0030118 41 34 0,000 0,03572263 0,0444765 ! cell growth GO:0016049 36 34 0,000 0,03572263 0,04446132 ! regulation of B cell activation GO:0050864 40 34 0,000 0,03572263 0,04444616 ! protein polymerization GO:0051258 38 34 0,000 0,03572263 0,04443101 ! condensed chromosome kinetochore GO:0000777 52 34 0,000 0,03572263 0,04441586 ! learning GO:0007612 51 34 0,000 0,03572263 0,04440073 ! keratinization GO:0031424 40 34 0,000 0,03572263 0,04438561 ! ovulation cycle process GO:0022602 35 34 0,000 0,03572263 0,04437049 ! regulation of striated muscle tissue development GO:0016202 40 34 0,000 0,03572263 0,04435539 ! steroid hormone receptor binding GO:0035258 44 34 0,000 0,03572263 0,0443403 ! regulation of protein import into nucleus GO:0042306 36 34 0,000 0,03572263 0,04432522 ! erythrocyte homeostasis GO:0034101 40 34 0,000 0,03572263 0,04431015 ! amino acid binding GO:0016597 40 34 0,000 0,03572263 0,04429509 ! regulation of protein stability GO:0031647 35 34 0,000 0,03572263 0,04428003 ! specific RNA polymerase II transcription factor activity GO:0003704 41 34 0,000 0,03572263 0,04426499 ! glycogen metabolic process GO:0005977 48 34 0,000 0,03572263 0,04424996 ! pyrimidine nucleotide metabolic process GO:0006220 41 34 0,000 0,03572263 0,04423494 ! acetylglucosaminyltransferase activity GO:0008375 40 34 0,000 0,03572263 0,04421993 ! epithelial tube morphogenesis GO:0060562 38 34 0,000 0,03572263 0,04420493 ! protein kinase inhibitor activity GO:0004860 37 34 0,000 0,03572263 0,04418994 ! positive regulation of transcription factor activity GO:0051091 49 35 0,000 0,03675471 0,04545125 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 53 35 0,000 0,03675471 0,04543585 ! response to estrogen stimulus GO:0043627 48 35 0,000 0,03675471 0,04542046 ! inner ear morphogenesis GO:0042472 46 35 0,000 0,03675471 0,04540508 ! MHC protein complex GO:0042611 50 35 0,000 0,03675471 0,04538971 ! alcohol biosynthetic process GO:0046165 41 35 0,000 0,03675471 0,04537434 ! female gonad development GO:0008585 37 35 0,000 0,03675471 0,045359 ! mesenchymal cell development GO:0014031 40 35 0,000 0,03675471 0,04534366 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! neutral lipid metabolic process GO:0006638 47 35 0,000 0,03675471 0,04532833 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 37 35 0,000 0,03675471 0,04531301 ! kinase inhibitor activity GO:0019210 47 35 0,000 0,03675471 0,0452977 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 41 35 0,000 0,03675471 0,0452824 ! regulation of proteolysis GO:0030162 37 35 0,000 0,03675471 0,04526711 ! ovulation cycle GO:0042698 37 35 0,000 0,03675471 0,04525184 ! intramolecular oxidoreductase activity GO:0016860 35 35 0,000 0,03675471 0,04523657 ! positive regulation of catabolic process GO:0009896 38 35 0,000 0,03675471 0,04522131 ! glucan metabolic process GO:0044042 49 35 0,000 0,03675471 0,04520607 GO:0006073|cellular glucan metabolic process, ! regulation of muscle development GO:0048634 42 35 0,000 0,03675471 0,04519083 ! ER to Golgi vesicle-mediated transport GO:0006888 43 35 0,000 0,03675471 0,0451756 ! histone methyltransferase activity GO:0042054 40 35 0,000 0,03675471 0,04516039 ! cation:sugar symporter activity GO:0005402 37 35 0,000 0,03675471 0,04514518 GO:0005351|sugar:hydrogen symporter activity, ! carbohydrate homeostasis GO:0033500 49 35 0,000 0,03675471 0,04512999 GO:0042593|glucose homeostasis, ! cytosolic small ribosomal subunit GO:0022627 36 35 0,000 0,03675471 0,0451148 ! maintenance of protein location GO:0045185 45 35 0,000 0,03675471 0,04509963 ! polyol metabolic process GO:0019751 46 35 0,000 0,03675471 0,04508446 ! androgen receptor signaling pathway GO:0030521 47 35 0,000 0,03675471 0,04506931 ! O-acyltransferase activity GO:0008374 36 35 0,000 0,03675471 0,04505416 ! purinergic nucleotide receptor activity GO:0001614 40 36 0,000 0,03778575 0,04630245 GO:0016502|nucleotide receptor activity, ! mitochondrial respiratory chain complex I GO:0005747 37 36 0,000 0,03778575 0,04628691 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 42 36 0,000 0,03778575 0,04627137 ! positive regulation of neurogenesis GO:0050769 38 36 0,000 0,03778575 0,04625584 ! SMAD binding GO:0046332 39 36 0,000 0,03778575 0,04624032 ! negative regulation of cell activation GO:0050866 40 36 0,000 0,03778575 0,04622482 ! inositol or phosphatidylinositol kinase activity GO:0004428 51 36 0,000 0,03778575 0,04620932 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 36 0,000 0,03778575 0,04619384 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 38 36 0,000 0,03778575 0,04617836 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 36 0,000 0,03778575 0,0461629 ! hormone-mediated signaling GO:0009755 41 36 0,000 0,03778575 0,04614744 ! nucleus organization GO:0006997 42 36 0,000 0,03778575 0,046132 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 44 36 0,000 0,03778575 0,04611656 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 42 36 0,000 0,03778575 0,04610114 ! carboxypeptidase activity GO:0004180 37 36 0,000 0,03778575 0,04608573 ! cellular response to extracellular stimulus GO:0031668 37 36 0,000 0,03778575 0,04607032 ! energy coupled proton transport, down electrochemical gradient GO:0015985 37 36 0,000 0,03778575 0,04605493 GO:0015986|ATP synthesis coupled proton transport, ! female gamete generation GO:0007292 39 36 0,000 0,03778575 0,04603955 ! positive regulation of mast cell proliferation GO:0070668 43 36 0,000 0,03778575 0,04602418 GO:0050671|positive regulation of lymphocyte proliferation, ! maintenance of location in cell GO:0051651 38 36 0,000 0,03778575 0,04600881 ! activation of adenylate cyclase activity GO:0007190 44 37 0,000 0,03881574 0,04724718 ! regulation of hormone secretion GO:0046883 43 37 0,000 0,03881574 0,04723142 ! sugar transmembrane transporter activity GO:0051119 39 37 0,000 0,03881574 0,04721567 GO:0015144|carbohydrate transmembrane transporter activity, ! regulation of Rab protein signal transduction GO:0032483 40 37 0,000 0,03881574 0,04719993 GO:0032313|regulation of Rab GTPase activity, ! regulation of action potential in neuron GO:0019228 44 37 0,000 0,03881574 0,04718421 ! glycerol ether metabolic process GO:0006662 49 37 0,000 0,03881574 0,04716849 ! endoribonuclease activity GO:0004521 48 37 0,000 0,03881574 0,04715278 ! hindbrain development GO:0030902 43 37 0,000 0,03881574 0,04713708 ! isoprenoid metabolic process GO:0006720 41 37 0,000 0,03881574 0,0471214 ! pigmentation GO:0043473 51 37 0,000 0,03881574 0,04710572 ! regulation of neuron projection development GO:0010975 43 37 0,000 0,03881574 0,04709006 ! condensed chromosome, centromeric region GO:0000779 55 37 0,000 0,03881574 0,0470744 ! metalloexopeptidase activity GO:0008235 39 37 0,000 0,03881574 0,04705876 ! monocarboxylic acid transport GO:0015718 43 37 0,000 0,03881574 0,04704312 ! sensory perception of taste GO:0050909 37 37 0,000 0,03881574 0,0470275 ! cell junction organization GO:0034330 44 37 0,000 0,03881574 0,04701189 ! skeletal muscle fiber development GO:0048741 41 37 0,000 0,03881574 0,04699628 ! development of primary female sexual characteristics GO:0046545 40 37 0,000 0,03881574 0,04698069 GO:0046660|female sex differentiation, ! NADH dehydrogenase (ubiquinone) activity GO:0008137 38 37 0,000 0,03881574 0,04696511 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! ion transmembrane transport GO:0034220 38 37 0,000 0,03881574 0,04694954 ! regulation of lymphocyte mediated immunity GO:0002706 43 37 0,000 0,03881574 0,04693397 ! coated pit GO:0005905 44 37 0,000 0,03881574 0,04691842 ! positive regulation of leukocyte proliferation GO:0070665 47 37 0,000 0,03881574 0,04690288 GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of adenylate cyclase activity GO:0045762 45 38 0,000 0,03984468 0,04813026 ! regulation of translational initiation GO:0006446 50 38 0,000 0,03984468 0,04811432 ! negative regulation of binding GO:0051100 44 38 0,000 0,03984468 0,0480984 ! organic ether metabolic process GO:0018904 50 38 0,000 0,03984468 0,04808249 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 43 38 0,000 0,03984468 0,04806659 ! regulation of lymphocyte differentiation GO:0045619 51 38 0,000 0,03984468 0,0480507 ! carbon-carbon lyase activity GO:0016830 41 38 0,000 0,03984468 0,04803482 ! hydro-lyase activity GO:0016836 44 38 0,000 0,03984468 0,04801895 ! synapse organization GO:0050808 43 38 0,000 0,03984468 0,0480031 ! viral infectious cycle GO:0019058 40 38 0,000 0,03984468 0,04798725 ! phosphoinositide biosynthetic process GO:0046489 41 38 0,000 0,03984468 0,04797141 ! negative regulation of protein complex disassembly GO:0043242 42 38 0,000 0,03984468 0,04795558 ! organic anion transport GO:0015711 42 38 0,000 0,03984468 0,04793977 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 52 38 0,000 0,03984468 0,04792396 ! monosaccharide binding GO:0048029 41 38 0,000 0,03984468 0,04790817 ! muscle fiber development GO:0048747 42 38 0,000 0,03984468 0,04789238 ! development of primary male sexual characteristics GO:0046546 46 38 0,000 0,03984468 0,04787661 ! phagocytosis GO:0006909 44 38 0,000 0,03984468 0,04786084 ! regulation of ARF protein signal transduction GO:0032012 44 38 0,000 0,03984468 0,04784509 ! general RNA polymerase II transcription factor activity GO:0016251 43 38 0,000 0,03984468 0,04782934 ! DNA-directed RNA polymerase activity GO:0003899 49 38 0,000 0,03984468 0,04781361 GO:0034062|RNA polymerase activity, ! extrinsic to plasma membrane GO:0019897 43 38 0,000 0,03984468 0,04779789 ! cytosolic large ribosomal subunit GO:0022625 43 38 0,000 0,03984468 0,04778217 ! Rab GTPase activator activity GO:0005097 41 38 0,000 0,03984468 0,04776647 ! cellular response to insulin stimulus GO:0032869 47 38 0,000 0,03984468 0,04775078 ! monocarboxylic acid binding GO:0033293 44 39 0,000 0,04087257 0,04896655 ! induction of apoptosis by extracellular signals GO:0008624 44 39 0,000 0,04087257 0,04895047 ! heterocycle biosynthetic process GO:0018130 51 39 0,000 0,04087257 0,0489344 ! positive regulation of DNA binding GO:0043388 53 39 0,000 0,04087257 0,04891835 ! T cell differentiation GO:0030217 64 39 0,000 0,04087257 0,04890231 ! DNA-dependent ATPase activity GO:0008094 63 39 0,000 0,04087257 0,04888627 ! cell fate specification GO:0001708 55 39 0,000 0,04087257 0,04887025 ! positive regulation of cyclase activity GO:0031281 46 39 0,000 0,04087257 0,04885424 ! regulation of adaptive immune response GO:0002819 44 39 0,000 0,04087257 0,04883823 ! regulation of cell morphogenesis involved in differentiation GO:0010769 45 39 0,000 0,04087257 0,04882224 ! receptor-mediated endocytosis GO:0006898 44 39 0,000 0,04087257 0,04880626 ! regulation of metal ion transport GO:0010959 45 39 0,000 0,04087257 0,04879029 ! energy reserve metabolic process GO:0006112 53 39 0,000 0,04087257 0,04877433 ! amine receptor activity GO:0008227 48 39 0,000 0,04087257 0,04875838 ! cytoskeleton-dependent intracellular transport GO:0030705 42 39 0,000 0,04087257 0,04874244 ! embryonic skeletal system morphogenesis GO:0048704 46 39 0,000 0,04087257 0,04872651 ! neuropeptide receptor activity GO:0008188 41 39 0,000 0,04087257 0,04871059 ! double-strand break repair GO:0006302 70 39 0,000 0,04087257 0,04869469 ! pigment metabolic process GO:0042440 43 39 0,000 0,04087257 0,04867879 ! RNA modification GO:0009451 39 39 0,000 0,04087257 0,0486629 ! damaged DNA binding GO:0003684 51 40 0,000 0,04189942 0,04986919 ! regulation of intracellular protein transport GO:0033157 43 40 0,000 0,04189942 0,04985293 ! peroxisomal membrane GO:0005778 44 40 0,000 0,04189942 0,04983667 GO:0031903|microbody membrane, ! actin filament binding GO:0051015 41 40 0,000 0,04189942 0,04982043 ! positive regulation of cell development GO:0010720 43 40 0,000 0,04189942 0,04980419 ! ribonucleoside metabolic process GO:0009119 47 40 0,000 0,04189942 0,04978797 ! biopolymer methylation GO:0043414 45 40 0,000 0,04189942 0,04977176 ! neuron migration GO:0001764 43 40 0,000 0,04189942 0,04975556 ! regulation of protein secretion GO:0050708 45 40 0,000 0,04189942 0,04973937 ! oxidoreduction coenzyme metabolic process GO:0006733 45 40 0,000 0,04189942 0,04972319 ! dorsal/ventral pattern formation GO:0009953 42 40 0,000 0,04189942 0,04970702 ! regulation of actin filament polymerization GO:0030833 53 40 0,000 0,04189942 0,04969086 ! positive regulation of defense response GO:0031349 41 40 0,000 0,04189942 0,04967471 ! mammary gland development GO:0030879 47 40 0,000 0,04189942 0,04965857 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 50 40 0,000 0,04189942 0,04964244 ! neuropeptide binding GO:0042923 42 40 0,000 0,04189942 0,04962632 ! regulation of tube size GO:0035150 44 40 0,000 0,04189942 0,04961022 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 42 40 0,000 0,04189942 0,04959412 ! positive regulation of gene-specific transcription GO:0043193 46 40 0,000 0,04189942 0,04957803 ! regulation of leukocyte mediated immunity GO:0002703 46 40 0,000 0,04189942 0,04956196 ! inorganic anion transmembrane transporter activity GO:0015103 43 40 0,000 0,04189942 0,04954589 ! chromatin remodeling GO:0006338 44 40 0,000 0,04189942 0,04952984 ! solute:hydrogen symporter activity GO:0015295 44 40 0,000 0,04189942 0,04951379 ! protein amino acid N-linked glycosylation GO:0006487 46 41 0,000 0,04292522 0,05070959 ! Notch signaling pathway GO:0007219 46 41 0,000 0,04292522 0,05069317 ! induction of apoptosis by intracellular signals GO:0008629 56 41 0,000 0,04292522 0,05067677 ! peptide metabolic process GO:0006518 42 41 0,000 0,04292522 0,05066037 ! polysaccharide biosynthetic process GO:0000271 42 41 0,000 0,04292522 0,05064399 ! late endosome membrane GO:0031902 45 41 0,000 0,04292522 0,05062761 ! icosanoid metabolic process GO:0006690 51 41 0,000 0,04292522 0,05061125 ! positive regulation of lyase activity GO:0051349 48 41 0,000 0,04292522 0,0505949 ! integral to endoplasmic reticulum membrane GO:0030176 43 41 0,000 0,04292522 0,05057855 ! lamellipodium GO:0030027 56 41 0,000 0,04292522 0,05056222 ! glycolysis GO:0006096 43 41 0,000 0,04292522 0,0505459 ! branching morphogenesis of a tube GO:0048754 54 41 0,000 0,04292522 0,05052959 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 51 41 0,000 0,04292522 0,05051329 ! proton-transporting two-sector ATPase complex GO:0016469 42 41 0,000 0,04292522 0,050497 ! response to reactive oxygen species GO:0000302 49 42 0,000 0,04394998 0,05168586 ! cellular amide metabolic process GO:0043603 56 42 0,000 0,04394998 0,0516692 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 43 42 0,000 0,04394998 0,05165255 ! regulation of multicellular organism growth GO:0040014 46 42 0,000 0,04394998 0,05163592 ! integral to Golgi membrane GO:0030173 55 42 0,000 0,04394998 0,05161929 ! nuclear export GO:0051168 46 42 0,000 0,04394998 0,05160268 ! developmental growth GO:0048589 45 42 0,000 0,04394998 0,05158608 ! structural constituent of muscle GO:0008307 46 42 0,000 0,04394998 0,05156949 ! protein methyltransferase activity GO:0008276 49 42 0,000 0,04394998 0,0515529 ! metal cluster binding GO:0051540 47 42 0,000 0,04394998 0,05153633 GO:0051536|iron-sulfur cluster binding, ! feeding behavior GO:0007631 48 42 0,000 0,04394998 0,05151977 ! protein serine/threonine phosphatase activity GO:0004722 45 42 0,000 0,04394998 0,05150322 ! ribonucleoprotein complex assembly GO:0022618 47 42 0,000 0,04394998 0,05148668 ! RNA catabolic process GO:0006401 49 43 0,000 0,0449737 0,05266904 ! ear morphogenesis GO:0042471 56 43 0,000 0,0449737 0,05265213 ! cellular amino acid biosynthetic process GO:0008652 49 43 0,000 0,0449737 0,05263524 ! regulation of epithelial cell proliferation GO:0050678 50 43 0,000 0,0449737 0,05261836 ! positive regulation of growth GO:0045927 47 43 0,000 0,0449737 0,05260149 ! cell recognition GO:0008037 51 43 0,000 0,0449737 0,05258463 ! positive regulation of cytokine production GO:0001819 46 43 0,000 0,0449737 0,05256778 ! epithelial cell differentiation GO:0030855 56 43 0,000 0,0449737 0,05255095 ! gliogenesis GO:0042063 46 43 0,000 0,0449737 0,05253412 ! endosome transport GO:0016197 48 43 0,000 0,0449737 0,0525173 ! striated muscle contraction GO:0006941 45 43 0,000 0,0449737 0,0525005 ! positive regulation of cytokine biosynthetic process GO:0042108 48 43 0,000 0,0449737 0,0524837 ! antioxidant activity GO:0016209 53 43 0,000 0,0449737 0,05246692 ! sulfur compound biosynthetic process GO:0044272 47 43 0,000 0,0449737 0,05245014 ! activation of caspase activity GO:0006919 60 43 0,000 0,0449737 0,05243338 ! vascular process in circulatory system GO:0003018 48 43 0,000 0,0449737 0,05241663 ! histone modification GO:0016570 45 43 0,000 0,0449737 0,05239989 ! cellular amino acid derivative biosynthetic process GO:0042398 55 43 0,000 0,0449737 0,05238316 ! regulation of nucleocytoplasmic transport GO:0046822 46 44 0,000 0,04599637 0,05355722 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 50 44 0,000 0,04599637 0,05354013 ! negative regulation of cell migration GO:0030336 53 44 0,000 0,04599637 0,05352305 ! ATP synthesis coupled electron transport GO:0042773 45 44 0,000 0,04599637 0,05350599 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! nucleoside monophosphate biosynthetic process GO:0009124 50 44 0,000 0,04599637 0,05348893 ! chemokine activity GO:0008009 48 44 0,000 0,04599637 0,05347188 ! ruffle GO:0001726 50 44 0,000 0,04599637 0,05345485 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 51 44 0,000 0,04599637 0,05343783 ! regulation of neuron apoptosis GO:0043523 58 44 0,000 0,04599637 0,05342081 ! cartilage development GO:0051216 48 44 0,000 0,04599637 0,05340381 ! membrane fusion GO:0006944 52 44 0,000 0,04599637 0,05338682 ! channel regulator activity GO:0016247 54 44 0,000 0,04599637 0,05336984 ! excretion GO:0007588 53 44 0,000 0,04599637 0,05335287 ! male sex differentiation GO:0046661 52 44 0,000 0,04599637 0,05333591 ! protein phosphatase regulator activity GO:0019888 50 44 0,000 0,04599637 0,05331896 ! RNA elongation from RNA polymerase II promoter GO:0006368 49 44 0,000 0,04599637 0,05330203 ! amino acid activation GO:0043038 45 44 0,000 0,04599637 0,0532851 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! microbody part GO:0044438 48 44 0,000 0,04599637 0,05326818 GO:0044439|peroxisomal part, ! positive regulation of binding GO:0051099 59 45 0,000 0,04701801 0,05443405 ! solute:sodium symporter activity GO:0015370 51 45 0,000 0,04701801 0,05441678 ! transferase activity, transferring pentosyl groups GO:0016763 50 45 0,000 0,04701801 0,05439953 ! organellar ribosome GO:0000313 46 45 0,000 0,04701801 0,05438228 GO:0005761|mitochondrial ribosome, ! single-stranded DNA binding GO:0003697 48 45 0,000 0,04701801 0,05436504 ! intrinsic to Golgi membrane GO:0031228 60 45 0,000 0,04701801 0,05434781 ! transport vesicle GO:0030133 53 45 0,000 0,04701801 0,0543306 ! regulation of endocytosis GO:0030100 52 45 0,000 0,04701801 0,0543134 ! ligase activity, forming carbon-oxygen bonds GO:0016875 47 45 0,000 0,04701801 0,0542962 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! regulation of protein complex disassembly GO:0043244 49 45 0,000 0,04701801 0,05427902 ! nuclear matrix GO:0016363 56 45 0,000 0,04701801 0,05426185 ! unsaturated fatty acid metabolic process GO:0033559 55 45 0,000 0,04701801 0,05424469 ! regulation of T cell proliferation GO:0042129 53 45 0,000 0,04701801 0,05422754 ! regulation of myeloid leukocyte differentiation GO:0002761 54 45 0,000 0,04701801 0,0542104 ! DNA-dependent DNA replication GO:0006261 66 45 0,000 0,04701801 0,05419327 ! coated vesicle membrane GO:0030662 52 45 0,000 0,04701801 0,05417615 ! covalent chromatin modification GO:0016569 47 45 0,000 0,04701801 0,05415905 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 51 45 0,000 0,04701801 0,05414195 ! synaptosome GO:0019717 50 45 0,000 0,04701801 0,05412487 ! chemokine receptor binding GO:0042379 50 45 0,000 0,04701801 0,05410779 ! regulation of action potential GO:0001508 56 46 0,000 0,04803861 0,05526485 ! immunoglobulin mediated immune response GO:0016064 51 46 0,000 0,04803861 0,05524743 ! phosphatase regulator activity GO:0019208 53 46 0,000 0,04803861 0,05523002 ! regulation of inflammatory response GO:0050727 49 46 0,000 0,04803861 0,05521261 ! eye morphogenesis GO:0048592 57 46 0,000 0,04803861 0,05519522 ! regulation of JNK cascade GO:0046328 53 46 0,000 0,04803861 0,05517785 ! methylation GO:0032259 51 46 0,000 0,04803861 0,05516048 ! positive regulation of protein transport GO:0051222 50 46 0,000 0,04803861 0,05514312 ! regulation of ion transport GO:0043269 54 46 0,000 0,04803861 0,05512578 ! leukocyte migration GO:0050900 49 46 0,000 0,04803861 0,05510844 ! neuromuscular process GO:0050905 56 46 0,000 0,04803861 0,05509112 ! sulfotransferase activity GO:0008146 54 46 0,000 0,04803861 0,0550738 ! JNK cascade GO:0007254 48 46 0,000 0,04803861 0,0550565 ! SH3/SH2 adaptor activity GO:0005070 52 46 0,000 0,04803861 0,05503921 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 54 47 0,000 0,04905817 0,0561897 ! auxiliary transport protein activity GO:0015457 58 47 0,000 0,04905817 0,05617206 ! regulation of actin polymerization or depolymerization GO:0008064 60 47 0,000 0,04905817 0,05615444 ! carbon-oxygen lyase activity GO:0016835 53 47 0,000 0,04905817 0,05613682 ! regulation of protein polymerization GO:0032271 60 47 0,000 0,04905817 0,05611922 ! viral reproductive process GO:0022415 53 47 0,000 0,04905817 0,05610163 ! RNA elongation GO:0006354 52 47 0,000 0,04905817 0,05608404 ! negative regulation of immune system process GO:0002683 58 47 0,000 0,04905817 0,05606647 ! mRNA binding GO:0003729 65 47 0,000 0,04905817 0,05604892 ! response to insulin stimulus GO:0032868 57 47 0,000 0,04905817 0,05603137 ! axon GO:0030424 53 48 0,000 0,05007669 0,05717676 ! protein amino acid lipidation GO:0006497 53 48 0,000 0,05007669 0,05715887 ! stress-activated protein kinase signaling pathway GO:0031098 50 48 0,000 0,05007669 0,05714099 ! proteasome complex GO:0000502 50 48 0,000 0,05007669 0,05712312 ! glutamine family amino acid metabolic process GO:0009064 62 48 0,000 0,05007669 0,05710527 ! protein homooligomerization GO:0051260 63 48 0,000 0,05007669 0,05708742 ! regulation of cell projection organization GO:0031344 54 48 0,000 0,05007669 0,05706959 ! kinetochore GO:0000776 69 48 0,000 0,05007669 0,05705176 ! positive regulation of caspase activity GO:0043280 65 48 0,000 0,05007669 0,05703395 GO:0010952|positive regulation of peptidase activity, ! detection of stimulus involved in sensory perception GO:0050906 53 48 0,000 0,05007669 0,05701615 ! growth factor receptor binding GO:0070851 58 48 0,000 0,05007669 0,05699836 ! N-methyltransferase activity GO:0008170 53 48 0,000 0,05007669 0,05698058 ! inner ear development GO:0048839 60 48 0,000 0,05007669 0,05696282 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 57 48 0,000 0,05007669 0,05694506 ! amino acid transmembrane transporter activity GO:0015171 53 48 0,000 0,05007669 0,05692731 ! chromatin remodeling complex GO:0016585 54 48 0,000 0,05007669 0,05690958 ! B cell mediated immunity GO:0019724 53 48 0,000 0,05007669 0,05689186 ! steroid hormone receptor activity GO:0003707 61 48 0,000 0,05007669 0,05687414 ! protein N-terminus binding GO:0047485 57 48 0,000 0,05007669 0,05685644 ! cell cortex part GO:0044448 54 48 0,000 0,05007669 0,05683875 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 52 49 0,000 0,05109417 0,05797559 ! regulation of neurotransmitter levels GO:0001505 55 49 0,000 0,05109417 0,05795757 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 54 49 0,000 0,05109417 0,05793955 ! response to temperature stimulus GO:0009266 57 49 0,000 0,05109417 0,05792155 ! Golgi-associated vesicle GO:0005798 59 49 0,000 0,05109417 0,05790355 ! lipid modification GO:0030258 55 49 0,000 0,05109417 0,05788557 ! synaptic vesicle GO:0008021 56 49 0,000 0,05109417 0,0578676 ! regulation of gene expression, epigenetic GO:0040029 64 49 0,000 0,05109417 0,05784964 ! pyridoxal phosphate binding GO:0030170 63 49 0,000 0,05109417 0,05783169 GO:0070279|vitamin B6 binding, ! exonuclease activity GO:0004527 79 49 0,000 0,05109417 0,05781375 ! maintenance of location GO:0051235 62 49 0,000 0,05109417 0,05779582 ! negative regulation of cell motion GO:0051271 60 49 0,000 0,05109417 0,05777791 ! regulation of actin filament length GO:0030832 62 49 0,000 0,05109417 0,05776 ! nuclear periphery GO:0034399 60 49 0,000 0,05109417 0,05774211 ! regulation of muscle contraction GO:0006937 57 49 0,000 0,05109417 0,05772423 ! negative regulation of cytoskeleton organization GO:0051494 73 49 0,000 0,05109417 0,05770636 ! nucleotide-excision repair GO:0006289 53 49 0,000 0,05109417 0,0576885 ! regulation of mast cell proliferation GO:0070666 57 49 0,000 0,05109417 0,05767065 ! respiratory electron transport chain GO:0022904 51 50 0,000 0,05211062 0,05879973 ! DNA damage response, signal transduction GO:0042770 84 50 0,000 0,05211062 0,05878155 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,05211062 0,05876338 ! embryonic skeletal system development GO:0048706 59 50 0,000 0,05211062 0,05874522 ! glucose catabolic process GO:0006007 54 50 0,000 0,05211062 0,05872707 ! aging GO:0007568 92 50 0,000 0,05211062 0,05870894 ! generation of a signal involved in cell-cell signaling GO:0003001 59 50 0,000 0,05211062 0,05869081 ! heart morphogenesis GO:0003007 57 50 0,000 0,05211062 0,0586727 ! integrin binding GO:0005178 56 50 0,000 0,05211062 0,05865459 ! detection of abiotic stimulus GO:0009582 56 50 0,000 0,05211062 0,0586365 ! regulation of angiogenesis GO:0045765 56 51 0,000 0,05312603 0,05976064 ! positive regulation of cell migration GO:0030335 63 51 0,000 0,05312603 0,05974222 ! regulation of ossification GO:0030278 59 51 0,000 0,05312603 0,05972381 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 60 51 0,000 0,05312603 0,05970541 ! cellular polysaccharide metabolic process GO:0044264 65 51 0,000 0,05312603 0,05968703 ! endocrine system development GO:0035270 55 51 0,000 0,05312603 0,05966865 ! germ cell development GO:0007281 56 51 0,000 0,05312603 0,05965028 ! transferase activity, transferring sulfur-containing groups GO:0016782 60 52 0,000 0,05414041 0,06077053 ! regulation of cellular component size GO:0032535 66 52 0,000 0,05414041 0,06075184 ! carbohydrate transport GO:0008643 57 52 0,000 0,05414041 0,06073316 ! regulation of lymphocyte proliferation GO:0050670 61 52 0,000 0,05414041 0,06071449 ! ubiquitin thiolesterase activity GO:0004221 64 52 0,000 0,05414041 0,06069583 ! nucleoside monophosphate metabolic process GO:0009123 58 52 0,000 0,05414041 0,06067718 ! cell maturation GO:0048469 68 52 0,000 0,05414041 0,06065855 ! regulation of intracellular transport GO:0032386 57 52 0,000 0,05414041 0,06063992 ! vesicle organization GO:0016050 59 52 0,000 0,05414041 0,06062131 ! kidney development GO:0001822 55 52 0,000 0,05414041 0,06060271 ! cellular component disassembly GO:0022411 69 52 0,000 0,05414041 0,06058412 ! cell redox homeostasis GO:0045454 57 52 0,000 0,05414041 0,06056554 ! lipoprotein biosynthetic process GO:0042158 57 52 0,000 0,05414041 0,06054697 ! lipid transporter activity GO:0005319 58 52 0,000 0,05414041 0,06052842 ! cytokine receptor activity GO:0004896 54 52 0,000 0,05414041 0,06050988 ! antiporter activity GO:0015297 53 52 0,000 0,05414041 0,06049134 ! embryonic limb morphogenesis GO:0030326 62 53 0,000 0,05515376 0,06160469 GO:0035113|embryonic appendage morphogenesis, ! glycosaminoglycan metabolic process GO:0030203 60 53 0,000 0,05515376 0,06158584 ! keratinocyte differentiation GO:0030216 60 53 0,000 0,05515376 0,06156699 ! N-acetyltransferase activity GO:0008080 59 53 0,000 0,05515376 0,06154816 ! basement membrane GO:0005604 55 53 0,000 0,05515376 0,06152934 ! water-soluble vitamin metabolic process GO:0006767 59 53 0,000 0,05515376 0,06151053 ! negative regulation of response to stimulus GO:0048585 68 53 0,000 0,05515376 0,06149173 ! viral reproduction GO:0016032 59 53 0,000 0,05515376 0,06147294 ! chloride transport GO:0006821 60 53 0,000 0,05515376 0,06145416 ! oxygen and reactive oxygen species metabolic process GO:0006800 58 53 0,000 0,05515376 0,0614354 ! regulation of protein catabolic process GO:0042176 56 53 0,000 0,05515376 0,06141664 ! regulation of DNA replication GO:0006275 75 53 0,000 0,05515376 0,0613979 ! DNA catabolic process GO:0006308 57 53 0,000 0,05515376 0,06137917 ! heterocycle catabolic process GO:0046700 56 53 0,000 0,05515376 0,06136045 ! integrin-mediated signaling pathway GO:0007229 59 53 0,000 0,05515376 0,06134175 ! regulation of leukocyte proliferation GO:0070663 65 53 0,000 0,05515376 0,06132305 GO:0032944|regulation of mononuclear cell proliferation, ! single fertilization GO:0007338 58 53 0,000 0,05515376 0,06130437 ! activation of phospholipase C activity GO:0007202 61 54 0,000 0,05616608 0,06241056 GO:0010863|positive regulation of phospholipase C activity, ! double-stranded DNA binding GO:0003690 63 54 0,000 0,05616608 0,06239155 ! mitochondrial respiratory chain GO:0005746 55 54 0,000 0,05616608 0,06237256 ! nucleoside metabolic process GO:0009116 62 54 0,000 0,05616608 0,06235358 ! coated membrane GO:0048475 65 54 0,000 0,05616608 0,06233461 GO:0030117|membrane coat, ! nucleosome GO:0000786 59 54 0,000 0,05616608 0,06231565 ! regulation of protein complex assembly GO:0043254 67 54 0,000 0,05616608 0,0622967 ! cellular defense response GO:0006968 61 54 0,000 0,05616608 0,06227777 ! gastrulation GO:0007369 62 54 0,000 0,05616608 0,06225885 ! dendrite GO:0030425 60 55 0,000 0,05717737 0,06336058 ! positive regulation of phospholipase activity GO:0010518 62 55 0,000 0,05717737 0,06334134 ! respiratory chain GO:0070469 57 55 0,000 0,05717737 0,06332211 ! coenzyme biosynthetic process GO:0009108 68 55 0,000 0,05717737 0,06330289 ! extracellular matrix organization GO:0030198 77 55 0,000 0,05717737 0,06328369 ! positive regulation of cell motion GO:0051272 69 55 0,000 0,05717737 0,06326449 ! protein amino acid autophosphorylation GO:0046777 61 55 0,000 0,05717737 0,06324531 ! translation initiation factor activity GO:0003743 66 55 0,000 0,05717737 0,06322614 ! steroid hormone receptor signaling pathway GO:0030518 70 55 0,000 0,05717737 0,06320698 ! regulation of bone remodeling GO:0046850 64 56 0,000 0,05818762 0,06430429 ! heat shock protein binding GO:0031072 62 56 0,000 0,05818762 0,06428481 ! late endosome GO:0005770 60 56 0,000 0,05818762 0,06426535 ! regulation of phospholipase activity GO:0010517 63 56 0,000 0,05818762 0,0642459 ! sphingolipid metabolic process GO:0006665 60 56 0,000 0,05818762 0,06422646 ! intrinsic to endoplasmic reticulum membrane GO:0031227 61 56 0,000 0,05818762 0,06420703 ! ribonuclease activity GO:0004540 67 56 0,000 0,05818762 0,06418762 ! positive regulation of T cell activation GO:0050870 74 56 0,000 0,05818762 0,06416821 ! mesoderm development GO:0007498 67 56 0,000 0,05818762 0,06414882 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 61 56 0,000 0,05818762 0,06412944 ! antigen processing and presentation GO:0019882 73 56 0,000 0,05818762 0,06411007 ! proton transport GO:0015992 59 56 0,000 0,05818762 0,06409072 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 57 0,000 0,05919685 0,06518265 ! glycerophospholipid biosynthetic process GO:0046474 71 57 0,000 0,05919685 0,06516298 ! diacylglycerol binding GO:0019992 65 57 0,000 0,05919685 0,06514332 ! B cell activation GO:0042113 63 57 0,000 0,05919685 0,06512368 ! small ribosomal subunit GO:0015935 58 57 0,000 0,05919685 0,06510405 ! detection of external stimulus GO:0009581 64 57 0,000 0,05919685 0,06508442 ! occluding junction GO:0070160 75 58 0,000 0,06020505 0,06617296 GO:0005923|tight junction, ! epidermal cell differentiation GO:0009913 66 58 0,000 0,06020505 0,06615302 ! hydrogen transport GO:0006818 61 58 0,000 0,06020505 0,0661331 ! receptor signaling protein serine/threonine kinase activity GO:0004702 64 58 0,000 0,06020505 0,0661132 ! lymphocyte mediated immunity GO:0002449 65 58 0,000 0,06020505 0,0660933 ! response to nutrient GO:0007584 68 58 0,000 0,06020505 0,06607342 ! large ribosomal subunit GO:0015934 64 58 0,000 0,06020505 0,06605355 ! regulation of tissue remodeling GO:0034103 66 58 0,000 0,06020505 0,06603369 ! ligand-dependent nuclear receptor activity GO:0004879 72 58 0,000 0,06020505 0,06601384 ! myosin complex GO:0016459 64 58 0,000 0,06020505 0,065994 ! regulation of gene-specific transcription GO:0032583 69 59 0,000 0,06121223 0,06707787 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 62 59 0,000 0,06121223 0,06705772 GO:0051213|dioxygenase activity, ! muscle cell differentiation GO:0042692 77 59 0,000 0,06121223 0,06703759 ! actin filament organization GO:0007015 65 59 0,000 0,06121223 0,06701747 ! regulation of heart contraction GO:0008016 71 59 0,000 0,06121223 0,06699736 ! hexose catabolic process GO:0019320 64 59 0,000 0,06121223 0,06697727 ! cellular amino acid catabolic process GO:0009063 63 59 0,000 0,06121223 0,06695719 ! response to steroid hormone stimulus GO:0048545 74 59 0,000 0,06121223 0,06693711 ! cell projection assembly GO:0030031 79 59 0,000 0,06121223 0,06691706 ! regulation of cellular response to stress GO:0080135 79 59 0,000 0,06121223 0,06689701 ! appendage morphogenesis GO:0035107 68 59 0,000 0,06121223 0,06687697 GO:0035108|limb morphogenesis, ! homeostasis of number of cells GO:0048872 67 59 0,000 0,06121223 0,06685695 ! fertilization GO:0009566 65 59 0,000 0,06121223 0,06683694 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 62 59 0,000 0,06121223 0,06681694 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 69 59 0,000 0,06121223 0,06679695 ! adult behavior GO:0030534 72 59 0,000 0,06121223 0,06677698 ! positive regulation of secretion GO:0051047 66 60 0,000 0,06221838 0,0678543 ! molecular adaptor activity GO:0060090 73 60 0,000 0,06221838 0,06783402 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 63 60 0,000 0,06221838 0,06781376 ! phosphoinositide metabolic process GO:0030384 68 60 0,000 0,06221838 0,0677935 ! copper ion binding GO:0005507 85 60 0,000 0,06221838 0,06777326 ! positive regulation of lipase activity GO:0060193 68 60 0,000 0,06221838 0,06775303 ! activation of immune response GO:0002253 72 60 0,000 0,06221838 0,06773281 ! appendage development GO:0048736 69 60 0,000 0,06221838 0,0677126 GO:0060173|limb development, ! regulation of vesicle-mediated transport GO:0060627 69 60 0,000 0,06221838 0,06769241 ! secondary metabolic process GO:0019748 67 60 0,000 0,06221838 0,06767223 ! cellular hormone metabolic process GO:0034754 64 61 0,000 0,0632235 0,06874496 ! ear development GO:0043583 76 61 0,000 0,0632235 0,06872448 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 68 61 0,000 0,0632235 0,068704 ! learning or memory GO:0007611 79 61 0,000 0,0632235 0,06868354 ! Ras GTPase binding GO:0017016 78 61 0,000 0,0632235 0,0686631 ! camera-type eye development GO:0043010 69 61 0,000 0,0632235 0,06864266 ! transcription initiation from RNA polymerase II promoter GO:0006367 69 61 0,000 0,0632235 0,06862224 ! regulation of transcription factor activity GO:0051090 80 62 0,000 0,06422761 0,06969135 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 90 62 0,000 0,06422761 0,06967062 ! lysosomal membrane GO:0005765 69 62 0,000 0,06422761 0,06964991 ! membrane lipid metabolic process GO:0006643 76 62 0,000 0,06422761 0,06962921 ! nuclear pore GO:0005643 79 62 0,000 0,06422761 0,06960853 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 77 62 0,000 0,06422761 0,06958785 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 77 62 0,000 0,06422761 0,06956719 ! chloride channel activity GO:0005254 72 62 0,000 0,06422761 0,06954654 ! cell soma GO:0043025 68 62 0,000 0,06422761 0,06952591 ! microtubule motor activity GO:0003777 94 62 0,000 0,06422761 0,06950528 ! intracellular receptor-mediated signaling pathway GO:0030522 80 62 0,000 0,06422761 0,06948467 ! focal adhesion GO:0005925 72 62 0,000 0,06422761 0,06946407 ! protein maturation by peptide bond cleavage GO:0051605 69 62 0,000 0,06422761 0,06944348 ! negative regulation of cell growth GO:0030308 69 63 0,000 0,06523068 0,07050712 ! FAD binding GO:0050660 71 63 0,000 0,06523068 0,07048624 ! urogenital system development GO:0001655 75 63 0,000 0,06523068 0,07046536 ! regulation of synaptic transmission GO:0050804 79 63 0,000 0,06523068 0,0704445 ! aminoglycan metabolic process GO:0006022 70 63 0,000 0,06523068 0,07042366 ! cAMP-mediated signaling GO:0019933 75 63 0,000 0,06523068 0,07040282 ! amine transmembrane transporter activity GO:0005275 69 63 0,000 0,06523068 0,070382 ! regulation of immune effector process GO:0002697 81 63 0,000 0,06523068 0,07036119 ! negative regulation of protein kinase activity GO:0006469 78 64 0,000 0,06623274 0,07142094 ! respiratory tube development GO:0030323 92 64 0,000 0,06623274 0,07139984 ! intracellular protein transmembrane transport GO:0065002 83 64 0,000 0,06623274 0,07137874 ! tRNA processing GO:0008033 73 64 0,000 0,06623274 0,07135766 ! negative regulation of ligase activity GO:0051352 79 64 0,000 0,06623274 0,07133659 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of myeloid cell differentiation GO:0045637 77 64 0,000 0,06623274 0,07131554 ! adaptive immune response GO:0002250 70 64 0,000 0,06623274 0,07129449 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! transition metal ion transport GO:0000041 74 64 0,000 0,06623274 0,07127346 ! neurotransmitter transport GO:0006836 72 64 0,000 0,06623274 0,07125245 ! regulation of actin cytoskeleton organization GO:0032956 93 64 0,000 0,06623274 0,07123144 ! nuclear hormone receptor binding GO:0035257 79 64 0,000 0,06623274 0,07121045 ! N-acyltransferase activity GO:0016410 70 64 0,000 0,06623274 0,07118946 ! negative regulation of cell size GO:0045792 71 65 0,000 0,06723378 0,07224413 ! multicellular organism reproduction GO:0032504 71 65 0,000 0,06723378 0,07222286 GO:0048609|reproductive process in a multicellular organism, ! lymphocyte differentiation GO:0030098 93 65 0,000 0,06723378 0,0722016 ! positive regulation of lymphocyte activation GO:0051251 83 65 0,000 0,06723378 0,07218035 ! negative regulation of kinase activity GO:0033673 79 65 0,000 0,06723378 0,07215911 ! regulation of cytokine biosynthetic process GO:0042035 84 65 0,000 0,06723378 0,07213789 ! activation of MAPK activity GO:0000187 74 65 0,000 0,06723378 0,07211668 ! gonad development GO:0008406 71 65 0,000 0,06723378 0,07209548 ! acetyltransferase activity GO:0016407 73 65 0,000 0,06723378 0,07207429 ! protein import into nucleus GO:0006606 73 66 0,000 0,0682338 0,07312482 ! developmental maturation GO:0021700 85 66 0,000 0,0682338 0,07310334 ! myeloid cell differentiation GO:0030099 78 66 0,000 0,0682338 0,07308188 ! leukocyte mediated immunity GO:0002443 73 66 0,000 0,0682338 0,07306043 ! tube morphogenesis GO:0035239 84 66 0,000 0,0682338 0,07303899 ! cysteine-type endopeptidase activity GO:0004197 73 66 0,000 0,0682338 0,07301757 ! cell-substrate adherens junction GO:0005924 76 66 0,000 0,0682338 0,07299616 ! endoplasmic reticulum lumen GO:0005788 78 67 0,000 0,0692328 0,07404317 ! glycerolipid biosynthetic process GO:0045017 81 67 0,000 0,0692328 0,07402146 ! nuclear import GO:0051170 74 67 0,000 0,0692328 0,07399978 ! response to peptide hormone stimulus GO:0043434 79 67 0,000 0,0692328 0,0739781 ! activation of protein kinase activity GO:0032147 83 67 0,000 0,0692328 0,07395644 ! regulation of actin filament-based process GO:0032970 96 67 0,000 0,0692328 0,07393479 ! chloride ion binding GO:0031404 79 67 0,000 0,0692328 0,07391315 ! humoral immune response GO:0006959 75 67 0,000 0,0692328 0,07389153 ! amine binding GO:0043176 77 67 0,000 0,0692328 0,07386991 ! female pregnancy GO:0007565 78 67 0,000 0,0692328 0,07384831 ! extrinsic to membrane GO:0019898 75 67 0,000 0,0692328 0,07382673 ! anion channel activity GO:0005253 77 67 0,000 0,0692328 0,07380515 ! regulation of homeostatic process GO:0032844 88 67 0,000 0,0692328 0,07378359 ! regulation of adenylate cyclase activity GO:0045761 81 68 0,000 0,07023078 0,07482531 ! amine catabolic process GO:0009310 73 68 0,000 0,07023078 0,07480347 ! negative regulation of organelle organization GO:0010639 93 68 0,000 0,07023078 0,07478163 ! monosaccharide catabolic process GO:0046365 73 68 0,000 0,07023078 0,07475981 ! cell-substrate junction GO:0030055 78 68 0,000 0,07023078 0,074738 ! respiratory system development GO:0060541 96 68 0,000 0,07023078 0,07471621 ! mRNA transport GO:0051028 88 69 0,000 0,07122774 0,07575475 ! fatty acid biosynthetic process GO:0006633 76 69 0,000 0,07122774 0,07573267 ! small GTPase binding GO:0031267 86 69 0,000 0,07122774 0,07571061 ! regulation of transmission of nerve impulse GO:0051969 87 69 0,000 0,07122774 0,07568855 ! sarcomere GO:0030017 74 69 0,000 0,07122774 0,07566651 ! exocytosis GO:0006887 76 69 0,000 0,07122774 0,07564448 ! skeletal muscle tissue development GO:0007519 75 69 0,000 0,07122774 0,07562247 GO:0060538|skeletal muscle organ development, ! nucleosome assembly GO:0006334 87 69 0,000 0,07122774 0,07560047 ! extracellular ligand-gated ion channel activity GO:0005230 82 69 0,000 0,07122774 0,07557848 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 79 69 0,000 0,07122774 0,0755565 ! amine biosynthetic process GO:0009309 78 70 0,000 0,07222369 0,0765907 ! thiolester hydrolase activity GO:0016790 84 70 0,000 0,07222369 0,07656845 ! early endosome GO:0005769 104 70 0,000 0,07222369 0,0765462 ! regulation of cyclase activity GO:0031279 83 70 0,000 0,07222369 0,07652397 ! negative regulation of transferase activity GO:0051348 85 70 0,000 0,07222369 0,07650175 ! regulation of lipase activity GO:0060191 78 70 0,000 0,07222369 0,07647954 ! amino acid transport GO:0006865 76 70 0,000 0,07222369 0,07645735 ! chromatin assembly GO:0031497 88 70 0,000 0,07222369 0,07643517 ! hormone receptor binding GO:0051427 85 70 0,000 0,07222369 0,076413 ! calcium channel activity GO:0005262 86 70 0,000 0,07222369 0,07639084 ! axon guidance GO:0007411 87 70 0,000 0,07222369 0,0763687 ! cell cortex GO:0005938 77 70 0,000 0,07222369 0,07634657 ! nuclear chromosome part GO:0044454 94 70 0,000 0,07222369 0,07632446 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 73 71 0,000 0,07321862 0,07735347 ! mitochondrial outer membrane GO:0005741 81 71 0,000 0,07321862 0,07733108 ! protein localization in nucleus GO:0034504 78 71 0,000 0,07321862 0,0773087 ! lipoprotein metabolic process GO:0042157 76 71 0,000 0,07321862 0,07728633 ! pore complex GO:0046930 89 72 0,000 0,07421255 0,0783128 ! response to hypoxia GO:0001666 84 72 0,000 0,07421255 0,07829016 ! steroid biosynthetic process GO:0006694 83 72 0,000 0,07421255 0,07826752 ! regulation of MAPKKK cascade GO:0043408 82 72 0,000 0,07421255 0,0782449 ! regulation of lyase activity GO:0051339 85 72 0,000 0,07421255 0,0782223 ! apical junction complex GO:0043296 90 72 0,000 0,07421255 0,0781997 ! phospholipase activity GO:0004620 99 72 0,000 0,07421255 0,07817712 ! membrane raft GO:0045121 81 72 0,000 0,07421255 0,07815455 ! regulation of neurological system process GO:0031644 91 72 0,000 0,07421255 0,078132 ! structural constituent of cytoskeleton GO:0005200 78 72 0,000 0,07421255 0,07810945 ! elevation of cytosolic calcium ion concentration GO:0007204 87 73 0,000 0,07520545 0,07913167 GO:0051480|cytosolic calcium ion homeostasis, ! response to drug GO:0042493 94 73 0,000 0,07520545 0,07910885 ! protein transporter activity GO:0008565 80 73 0,000 0,07520545 0,07908605 ! regulation of cAMP biosynthetic process GO:0030817 86 73 0,000 0,07520545 0,07906325 ! exopeptidase activity GO:0008238 81 73 0,000 0,07520545 0,07904048 ! digestion GO:0007586 81 73 0,000 0,07520545 0,07901771 ! positive regulation of leukocyte activation GO:0002696 92 73 0,000 0,07520545 0,07899496 ! regulation of Rho protein signal transduction GO:0035023 88 73 0,000 0,07520545 0,07897222 ! response to oxygen levels GO:0070482 86 74 0,000 0,07619735 0,07999077 ! potassium channel complex GO:0034705 84 74 0,000 0,07619735 0,07996776 GO:0008076|voltage-gated potassium channel complex, ! GTPase binding GO:0051020 91 74 0,000 0,07619735 0,07994476 ! protein-DNA complex assembly GO:0065004 101 74 0,000 0,07619735 0,07992177 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 85 74 0,000 0,07619735 0,0798988 ! one-carbon metabolic process GO:0006730 84 74 0,000 0,07619735 0,07987584 ! blood coagulation GO:0007596 90 74 0,000 0,07619735 0,0798529 GO:0050817|coagulation, ! reproductive structure development GO:0048608 89 74 0,000 0,07619735 0,07982996 ! apicolateral plasma membrane GO:0016327 92 74 0,000 0,07619735 0,07980704 ! phosphoinositide-mediated signaling GO:0048015 92 74 0,000 0,07619735 0,07978414 ! cellular lipid catabolic process GO:0044242 99 74 0,000 0,07619735 0,07976124 ! ubiquitin ligase complex GO:0000151 91 74 0,000 0,07619735 0,07973836 ! cell projection part GO:0044463 80 74 0,000 0,07619735 0,0797155 ! meiosis GO:0007126 108 75 0,000 0,07718824 0,08072898 GO:0051327|M phase of meiotic cell cycle, ! regulation of DNA binding GO:0051101 94 75 0,000 0,07718824 0,08070584 ! carboxylic acid transmembrane transporter activity GO:0046943 85 75 0,000 0,07718824 0,08068272 ! positive regulation of cell activation GO:0050867 94 75 0,000 0,07718824 0,08065961 ! regulation of cAMP metabolic process GO:0030814 88 75 0,000 0,07718824 0,08063651 ! regulation of blood pressure GO:0008217 82 75 0,000 0,07718824 0,08061342 ! transcription initiation GO:0006352 84 75 0,000 0,07718824 0,08059035 ! Ras GTPase activator activity GO:0005099 83 75 0,000 0,07718824 0,08056729 ! negative regulation of growth GO:0045926 85 76 0,000 0,07817811 0,08157716 ! defense response to bacterium GO:0042742 81 76 0,000 0,07817811 0,08155383 ! regulation of lipid metabolic process GO:0019216 98 76 0,000 0,07817811 0,08153052 ! cell leading edge GO:0031252 97 76 0,000 0,07817811 0,08150722 ! meiotic cell cycle GO:0051321 109 76 0,000 0,07817811 0,08148393 ! regulation of neuron differentiation GO:0045664 96 76 0,000 0,07817811 0,08146065 ! condensed chromosome GO:0000793 106 76 0,000 0,07817811 0,08143739 ! protein-DNA complex GO:0032993 93 76 0,000 0,07817811 0,08141414 ! organic acid transmembrane transporter activity GO:0005342 86 76 0,000 0,07817811 0,08139091 ! development of primary sexual characteristics GO:0045137 86 76 0,000 0,07817811 0,08136769 ! cytosolic ribosome GO:0022626 82 76 0,000 0,07817811 0,08134448 ! serine-type endopeptidase inhibitor activity GO:0004867 93 76 0,000 0,07817811 0,08132129 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 84 77 0,000 0,07916698 0,08232644 ! nucleosome organization GO:0034728 96 77 0,000 0,07916698 0,08230297 ! alcohol catabolic process GO:0046164 84 77 0,000 0,07916698 0,08227953 ! vacuolar membrane GO:0005774 86 77 0,000 0,07916698 0,08225609 ! G-protein-coupled receptor binding GO:0001664 87 77 0,000 0,07916698 0,08223267 ! regulation of Ras GTPase activity GO:0032318 88 77 0,000 0,07916698 0,08220926 ! establishment of RNA localization GO:0051236 97 77 0,000 0,07916698 0,08218587 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! myofibril GO:0030016 82 77 0,000 0,07916698 0,08216249 ! protein oligomerization GO:0051259 93 77 0,000 0,07916698 0,08213912 ! phosphoric diester hydrolase activity GO:0008081 99 78 0,000 0,08015484 0,08314042 ! endonuclease activity GO:0004519 111 78 0,000 0,08015484 0,08311678 ! cofactor biosynthetic process GO:0051188 93 78 0,000 0,08015484 0,08309316 ! inorganic anion transport GO:0015698 87 78 0,000 0,08015484 0,08306956 ! regulation of protein transport GO:0051223 85 78 0,000 0,08015484 0,08304597 ! regulation of nucleotide biosynthetic process GO:0030808 91 78 0,000 0,08015484 0,08302239 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! transmembrane receptor protein kinase activity GO:0019199 95 78 0,000 0,08015484 0,08299882 ! carboxylesterase activity GO:0004091 93 78 0,000 0,08015484 0,08297527 ! protein ubiquitination GO:0016567 95 78 0,000 0,08015484 0,08295173 ! contractile fiber part GO:0044449 83 78 0,000 0,08015484 0,0829282 ! RNA localization GO:0006403 99 79 0,000 0,08114169 0,0839254 ! positive regulation of MAP kinase activity GO:0043406 89 79 0,000 0,08114169 0,08390161 ! vitamin metabolic process GO:0006766 86 79 0,000 0,08114169 0,08387784 ! T cell activation GO:0042110 120 79 0,000 0,08114169 0,08385407 ! cellular response to hormone stimulus GO:0032870 94 79 0,000 0,08114169 0,08383033 ! phosphoinositide binding GO:0035091 99 79 0,000 0,08114169 0,08380659 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 88 80 0,000 0,08212754 0,08480081 ! eye development GO:0001654 93 80 0,000 0,08212754 0,08477681 ! ATP biosynthetic process GO:0006754 89 80 0,000 0,08212754 0,08475283 ! rhythmic process GO:0048511 90 80 0,000 0,08212754 0,08472886 ! regulation of catabolic process GO:0009894 87 80 0,000 0,08212754 0,08470491 ! hemostasis GO:0007599 96 80 0,000 0,08212754 0,08468096 ! regulation of cyclic nucleotide metabolic process GO:0030799 93 80 0,000 0,08212754 0,08465704 ! rRNA processing GO:0006364 84 80 0,000 0,08212754 0,08463312 ! cholesterol metabolic process GO:0008203 91 81 0,000 0,08311238 0,08562382 ! vacuolar part GO:0044437 91 81 0,000 0,08311238 0,08559965 ! biogenic amine metabolic process GO:0006576 99 82 0,000 0,08409622 0,08658848 ! forebrain development GO:0030900 93 82 0,000 0,08409622 0,08656405 ! external side of plasma membrane GO:0009897 105 82 0,000 0,08409622 0,08653963 ! cellular respiration GO:0045333 85 82 0,000 0,08409622 0,08651523 ! microtubule-based movement GO:0007018 119 83 0,000 0,08507905 0,08750166 ! nuclear speck GO:0016607 99 83 0,000 0,08507905 0,08747699 ! rRNA metabolic process GO:0016072 88 83 0,000 0,08507905 0,08745235 ! ATP-dependent helicase activity GO:0008026 107 83 0,000 0,08507905 0,08742771 GO:0070035|purine NTP-dependent helicase activity, ! regulation of cell adhesion GO:0030155 98 83 0,000 0,08507905 0,08740309 ! regulation of T cell activation GO:0050863 104 83 0,000 0,08507905 0,08737848 ! regulation of establishment of protein localization GO:0070201 90 83 0,000 0,08507905 0,08735389 ! oxidative phosphorylation GO:0006119 85 83 0,000 0,08507905 0,08732931 ! contractile fiber GO:0043292 88 83 0,000 0,08507905 0,08730475 ! regulation of nucleotide metabolic process GO:0006140 96 83 0,000 0,08507905 0,0872802 ! regulation of membrane potential GO:0042391 98 83 0,000 0,08507905 0,08725566 ! cilium GO:0005929 88 83 0,000 0,08507905 0,08723113 ! regulation of DNA metabolic process GO:0051052 139 84 0,000 0,08606088 0,08821301 ! regulation of defense response GO:0031347 98 84 0,000 0,08606088 0,08818823 ! nitrogen compound catabolic process GO:0044270 91 84 0,000 0,08606088 0,08816347 ! DNA recombination GO:0006310 147 84 0,000 0,08606088 0,08813872 ! phospholipid biosynthetic process GO:0008654 101 85 0,000 0,08704172 0,08911821 ! protein modification by small protein conjugation GO:0032446 103 85 0,000 0,08704172 0,0890932 ! monooxygenase activity GO:0004497 92 85 0,000 0,08704172 0,08906821 ! hydrogen ion transmembrane transporter activity GO:0015078 88 85 0,000 0,08704172 0,08904324 ! protein binding, bridging GO:0030674 104 85 0,000 0,08704172 0,08901827 ! negative regulation of transport GO:0051051 98 86 0,000 0,08802155 0,08999512 ! clathrin-coated vesicle GO:0030136 100 86 0,000 0,08802155 0,08996991 ! lipase activity GO:0016298 114 86 0,000 0,08802155 0,08994471 ! voltage-gated potassium channel activity GO:0005249 105 86 0,000 0,08802155 0,08991952 ! adherens junction GO:0005912 100 86 0,000 0,08802155 0,08989435 ! microtubule cytoskeleton organization GO:0000226 113 87 0,000 0,08900038 0,09086857 ! leukocyte differentiation GO:0002521 118 87 0,000 0,08900038 0,09084314 ! organelle outer membrane GO:0031968 102 88 0,000 0,08997821 0,09181553 ! carbohydrate biosynthetic process GO:0016051 95 88 0,000 0,08997821 0,09178986 ! growth factor binding GO:0019838 102 88 0,000 0,08997821 0,0917642 ! protein processing GO:0016485 100 88 0,000 0,08997821 0,09173855 ! protein tyrosine phosphatase activity GO:0004725 109 89 0,000 0,09095505 0,09270859 ! gland development GO:0048732 108 89 0,000 0,09095505 0,09268269 ! ATP metabolic process GO:0046034 100 90 0,000 0,09193089 0,09365091 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 101 90 0,000 0,09193089 0,09362476 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! peroxisome GO:0005777 100 90 0,000 0,09193089 0,09359863 GO:0042579|microbody, ! glycerophospholipid metabolic process GO:0006650 109 90 0,000 0,09193089 0,09357252 ! sterol metabolic process GO:0016125 102 90 0,000 0,09193089 0,09354642 ! negative regulation of multicellular organismal process GO:0051241 102 90 0,000 0,09193089 0,09352033 ! anion binding GO:0043168 104 90 0,000 0,09193089 0,09349426 ! amine transport GO:0015837 97 90 0,000 0,09193089 0,0934682 ! outer membrane GO:0019867 104 90 0,000 0,09193089 0,09344216 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 108 91 0,000 0,09290574 0,09440672 ! ribonucleoside triphosphate biosynthetic process GO:0009201 102 91 0,000 0,09290574 0,09438043 GO:0009142|nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 104 91 0,000 0,09290574 0,09435416 ! sulfur metabolic process GO:0006790 98 91 0,000 0,09290574 0,0943279 ! sex differentiation GO:0007548 103 91 0,000 0,09290574 0,09430165 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 112 91 0,000 0,09290574 0,09427542 ! hormone metabolic process GO:0042445 107 91 0,000 0,09290574 0,0942492 ! regulation of protein localization GO:0032880 99 91 0,000 0,09290574 0,094223 ! detection of stimulus GO:0051606 100 91 0,000 0,09290574 0,09419681 ! structure-specific DNA binding GO:0043566 112 92 0,000 0,09387959 0,09515775 ! anatomical structure homeostasis GO:0060249 121 92 0,000 0,09387959 0,09513132 ! regulation of cellular component biogenesis GO:0044087 115 92 0,000 0,09387959 0,0951049 ! carboxylic acid catabolic process GO:0046395 100 92 0,000 0,09387959 0,0950785 GO:0016054|organic acid catabolic process, ! translation factor activity, nucleic acid binding GO:0008135 108 92 0,000 0,09387959 0,09505211 ! regulation of GTPase activity GO:0043087 105 92 0,000 0,09387959 0,09502573 ! extracellular structure organization GO:0043062 119 92 0,000 0,09387959 0,09499938 ! cell cycle arrest GO:0007050 103 93 0,000 0,09485245 0,09595722 ! protein import GO:0017038 102 93 0,000 0,09485245 0,09593062 ! regulation of cytoskeleton organization GO:0051493 133 93 0,000 0,09485245 0,09590403 ! neurotransmitter receptor activity GO:0030594 104 93 0,000 0,09485245 0,09587746 ! response to nutrient levels GO:0031667 105 93 0,000 0,09485245 0,0958509 ! Ras protein signal transduction GO:0007265 118 93 0,000 0,09485245 0,09582435 ! protein modification by small protein conjugation or removal GO:0070647 112 93 0,000 0,09485245 0,09579782 ! ATPase activity, coupled to transmembrane movement of substances GO:0042626 102 94 0,000 0,09582432 0,09675259 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 104 94 0,000 0,09582432 0,09672582 ! morphogenesis of an epithelium GO:0002009 113 94 0,000 0,09582432 0,09669906 GO:0060429|epithelium development, ! anchoring junction GO:0070161 108 94 0,000 0,09582432 0,09667232 ! neurotransmitter binding GO:0042165 105 94 0,000 0,09582432 0,09664559 ! DNA packaging GO:0006323 113 94 0,000 0,09582432 0,09661888 ! ATPase activity, coupled to movement of substances GO:0043492 104 95 0,000 0,09679519 0,09757084 ! anterior/posterior pattern formation GO:0009952 109 95 0,000 0,09679519 0,09754388 ! protein localization in organelle GO:0033365 104 95 0,000 0,09679519 0,09751694 ! Wnt receptor signaling pathway GO:0016055 121 95 0,000 0,09679519 0,09749002 ! immune effector process GO:0002252 110 95 0,000 0,09679519 0,09746311 ! apical plasma membrane GO:0016324 105 95 0,000 0,09679519 0,09743622 ! translational elongation GO:0006414 104 96 0,000 0,09776508 0,09838538 ! hydrolase activity, acting on glycosyl bonds GO:0016798 109 96 0,000 0,09776508 0,09835824 ! in utero embryonic development GO:0001701 110 96 0,000 0,09776508 0,09833113 ! carbohydrate catabolic process GO:0016052 116 96 0,000 0,09776508 0,09830402 ! receptor complex GO:0043235 131 96 0,000 0,09776508 0,09827693 ! regulation of response to external stimulus GO:0032101 109 96 0,000 0,09776508 0,09824986 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 100 96 0,000 0,09776508 0,0982228 ! electron transport chain GO:0022900 104 97 0,000 0,09873397 0,09916892 ! microtubule associated complex GO:0005875 135 97 0,000 0,09873397 0,09914162 ! metalloendopeptidase activity GO:0004222 126 97 0,000 0,09873397 0,09911434 ! perinuclear region of cytoplasm GO:0048471 125 97 0,000 0,09873397 0,09908708 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances GO:0016820 105 97 0,000 0,09873397 0,09905982 ! carboxylic acid binding GO:0031406 108 97 0,000 0,09873397 0,09903259 ! protein maturation GO:0051604 109 97 0,000 0,09873397 0,09900537 ! UDP-glycosyltransferase activity GO:0008194 120 98 0,000 0,09970188 0,09994846 ! cell fate commitment GO:0045165 118 98 0,000 0,09970188 0,099921 ! negative regulation of cellular component organization GO:0051129 132 99 0,000 0,1006688 0,10086234 ! hormone activity GO:0005179 113 99 0,000 0,1006688 0,10083464 ! solute:cation symporter activity GO:0015294 110 99 0,000 0,1006688 0,10080696 ! nuclear chromosome GO:0000228 127 100 0,000 0,10163473 0,10174629 ! regulation of neurogenesis GO:0050767 123 100 0,000 0,10163473 0,10171838 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016810 105 100 0,000 0,10163473 0,10169048 ! regulation of lymphocyte activation GO:0051249 123 100 0,000 0,10163473 0,1016626 ! peptide receptor activity, G-protein coupled GO:0008528 107 100 0,000 0,10163473 0,10163473