pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/291-3-real-Zhou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL4685_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! B cell lineage commitment GO:0002326 17 7 2,000 9,718E-08 2,306E-04 ! negative regulation of protein ubiquitination GO:0031397 7 5 1,000 2,047E-05 0,02429314 ! B cell differentiation GO:0030183 70 40 2,000 2,656E-05 0,02100812 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 3,068E-05 0,01820337 ! positive regulation of Rho GTPase activity GO:0032321 12 6 1,000 3,068E-05 0,01456269 ! activation of caspase activity GO:0006919 70 46 2,000 4,057E-05 0,0160442 ! regulation of protein homodimerization activity GO:0043496 15 7 1,000 4,292E-05 0,01454951 ! positive regulation of caspase activity GO:0043280 77 51 2,000 5,538E-05 0,01642724 GO:0010952|positive regulation of peptidase activity, ! neurotransmitter uptake GO:0001504 10 8 1,000 5,717E-05 0,01507473 ! regulation of focal adhesion formation GO:0051893 17 8 1,000 5,717E-05 0,01356726 ! regulation of phosphoprotein phosphatase activity GO:0043666 20 10 1,000 9,172E-05 0,01978645 ! regulation of stress fiber formation GO:0051492 24 10 1,000 9,172E-05 0,01813757 ! positive regulation of Ras GTPase activity GO:0032320 24 10 1,000 9,172E-05 0,01674238 ! regulation of phosphatase activity GO:0010921 23 11 1,000 1,12E-04 0,01898408 ! L-glutamate transport GO:0015813 15 11 1,000 1,12E-04 0,01771847 GO:0015800|acidic amino acid transport, ! regulation of actin filament bundle formation GO:0032231 25 11 1,000 1,12E-04 0,01661107 ! B cell activation GO:0042113 119 66 2,000 1,199E-04 0,0167388 ! regulation of caspase activity GO:0043281 104 68 2,000 1,311E-04 0,01727986 ! positive regulation of GTPase activity GO:0043547 29 12 1,000 1,343E-04 0,01677074 ! regulation of Rho GTPase activity GO:0032319 22 12 1,000 1,343E-04 0,0159322 ! regulation of endopeptidase activity GO:0052548 106 70 2,000 1,429E-04 0,01614623 ! regulation of peptidase activity GO:0052547 113 75 2,000 1,754E-04 0,01891912 ! lymphocyte differentiation GO:0030098 135 75 2,000 1,754E-04 0,01809655 ! regulation of protein ubiquitination GO:0031396 20 14 1,000 1,848E-04 0,01827284 ! DNA fragmentation involved in apoptosis GO:0006309 20 16 1,000 2,433E-04 0,02309039 ! positive regulation of neuron apoptosis GO:0043525 30 16 1,000 2,433E-04 0,0222023 ! L-amino acid transport GO:0015807 27 17 1,000 2,754E-04 0,02420875 ! regulation of protein binding GO:0043393 29 17 1,000 2,754E-04 0,02334415 ! regulation of dephosphorylation GO:0035303 38 18 1,000 3,096E-04 0,02533365 ! leukocyte differentiation GO:0002521 165 94 2,000 3,418E-04 0,02703376 ! cell structure disassembly during apoptosis GO:0006921 25 20 1,000 3,838E-04 0,02937722 ! negative regulation of translation GO:0017148 28 20 1,000 3,838E-04 0,02845918 ! cell fate commitment GO:0045165 165 99 2,000 3,98E-04 0,02861692 ! apoptotic nuclear changes GO:0030262 31 21 1,000 4,238E-04 0,02957784 ! DNA catabolic process, endonucleolytic GO:0000737 27 22 1,000 4,657E-04 0,03157747 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 30 24 1,000 5,555E-04 0,03661463 ! regulation of cell-matrix adhesion GO:0001952 57 25 1,000 6,032E-04 0,03868788 GO:0010810|regulation of cell-substrate adhesion, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 38 26 1,000 6,529E-04 0,04077205 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 31 26 1,000 6,529E-04 0,03972661 ! negative regulation of protein modification process GO:0031400 56 28 1,000 7,58E-04 0,04496862 ! positive regulation of cell adhesion GO:0045785 54 29 1,000 8,134E-04 0,04707902 ! organic anion transport GO:0015711 50 30 1,000 8,707E-04 0,04919633 ! response to heat GO:0009408 43 30 1,000 8,707E-04 0,04805223 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 45 32 1,000 9,91E-04 0,05344866 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 47 35 1,000 1,186E-03 0,06252234 ! positive regulation of JAK-STAT cascade GO:0046427 49 37 1,000 1,325E-03 0,06833806 ! nucleus organization GO:0006997 58 37 1,000 1,325E-03 0,06688406 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 61 41 1,000 1,625E-03 0,08034338 ! RNA export from nucleus GO:0006405 57 41 1,000 1,625E-03 0,07870372 ! cellular component disassembly GO:0022411 66 44 1,000 1,87E-03 0,0887406 ! JAK-STAT cascade GO:0007259 62 44 1,000 1,87E-03 0,08700059 ! response to insulin stimulus GO:0032868 71 45 1,000 1,955E-03 0,08921565 ! regulation of translational initiation GO:0006446 70 46 1,000 2,042E-03 0,09142852 ! regulation of JAK-STAT cascade GO:0046425 68 46 1,000 2,042E-03 0,0897354 ! regulation of neuron apoptosis GO:0043523 84 48 1,000 2,221E-03 0,09584727 ! response to temperature stimulus GO:0009266 66 49 1,000 2,314E-03 0,09805296 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 74 51 1,000 2,504E-03 0,10425408 ! DNA catabolic process GO:0006308 71 56 1,000 3,011E-03 0,12319461 ! regulation of neurotransmitter levels GO:0001505 85 57 1,000 3,118E-03 0,1253973 ! mesoderm development GO:0007498 84 57 1,000 3,118E-03 0,12330734 ! nuclear export GO:0051168 85 57 1,000 3,118E-03 0,12128591 ! response to peptide hormone stimulus GO:0043434 97 60 1,000 3,448E-03 0,13198182 ! amino acid transport GO:0006865 97 62 1,000 3,677E-03 0,13851617 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 96 66 1,000 4,156E-03 0,1541101 ! neurotransmitter transport GO:0006836 92 67 1,000 4,28E-03 0,15626719 ! positive regulation of protein amino acid phosphorylation GO:0001934 103 68 1,000 4,406E-03 0,15842032 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 109 68 1,000 4,406E-03 0,15605584 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 104 70 1,000 4,663E-03 0,16271469 ! cell-matrix adhesion GO:0007160 133 71 1,000 4,794E-03 0,16485595 ! regulation of actin cytoskeleton organization GO:0032956 120 72 1,000 4,926E-03 0,16699326 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 108 73 1,000 5,06E-03 0,16912662 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 110 73 1,000 5,06E-03 0,16677764 ! regulation of actin filament-based process GO:0032970 122 74 1,000 5,196E-03 0,16891007 ! regulation of Rho protein signal transduction GO:0035023 126 74 1,000 5,196E-03 0,1666275 ! positive regulation of phosphorylation GO:0042327 119 75 1,000 5,334E-03 0,16875803 ! cell-substrate adhesion GO:0031589 141 76 1,000 5,473E-03 0,17088459 ! regulation of Ras GTPase activity GO:0032318 125 76 1,000 5,473E-03 0,16866531 ! positive regulation of ligase activity GO:0051351 114 76 1,000 5,473E-03 0,16650294 ! positive regulation of phosphorus metabolic process GO:0010562 125 77 1,000 5,614E-03 0,16862728 GO:0045937|positive regulation of phosphate metabolic process, ! mitochondrion organization GO:0007005 127 78 1,000 5,756E-03 0,17074773 ! amine transport GO:0015837 115 78 1,000 5,756E-03 0,16863973 ! regulation of ubiquitin-protein ligase activity GO:0051438 123 79 1,000 5,901E-03 0,17075619 ! response to unfolded protein GO:0006986 113 80 1,000 6,046E-03 0,17286881 ! regulation of ligase activity GO:0051340 129 82 1,000 6,343E-03 0,17919069 ! positive regulation of protein modification process GO:0031401 126 83 1,000 6,494E-03 0,18129174 ! cellular respiration GO:0045333 119 85 1,000 6,8E-03 0,18763901 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 130 85 1,000 6,8E-03 0,18548224 GO:0010498|proteasomal protein catabolic process, ! response to protein stimulus GO:0051789 127 85 1,000 6,8E-03 0,18337448 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 7,27E-03 0,19384814 ! positive regulation of protein ubiquitination GO:0031398 8 5 0,000 7,27E-03 0,19169427 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 5 0,000 7,27E-03 0,18958774 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 7,27E-03 0,187527 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! negative regulation of tyrosine phosphorylation of Stat3 protein GO:0042518 13 5 0,000 7,27E-03 0,18551058 GO:0042532|negative regulation of tyrosine phosphorylation of STAT protein, ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 7,27E-03 0,18353706 ! regulation of cGMP biosynthetic process GO:0030826 7 5 0,000 7,27E-03 0,1816051 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 7,27E-03 0,17971338 ! positive regulation of actin filament polymerization GO:0030838 8 5 0,000 7,27E-03 0,17786066 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 7 5 0,000 7,27E-03 0,17604576 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 7,27E-03 0,17426752 ! response to oxygen radical GO:0000305 11 5 0,000 7,27E-03 0,17252484 ! negative regulation of bone resorption GO:0045779 11 5 0,000 7,27E-03 0,17081667 ! myoblast cell fate commitment GO:0048625 8 5 0,000 7,27E-03 0,169142 ! nucleotide-sugar transport GO:0015780 8 5 0,000 7,27E-03 0,16749984 ! positive regulation of lipid biosynthetic process GO:0046889 7 5 0,000 7,27E-03 0,16588927 ! regulation of interferon-beta production GO:0032648 5 5 0,000 7,27E-03 0,16430937 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 6 5 0,000 7,27E-03 0,16275928 GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 6 5 0,000 7,27E-03 0,16123817 ! female meiosis GO:0007143 8 5 0,000 7,27E-03 0,15974522 ! nose development GO:0043584 10 5 0,000 7,27E-03 0,15827967 ! DNA catabolic process, exonucleolytic GO:0000738 7 5 0,000 7,27E-03 0,15684076 ! regulation of cell adhesion mediated by integrin GO:0033628 15 5 0,000 7,27E-03 0,15542778 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 7,27E-03 0,15404004 ! short-chain fatty acid metabolic process GO:0046459 8 5 0,000 7,27E-03 0,15267685 ! tryptophanyl-tRNA aminoacylation GO:0006436 6 5 0,000 7,27E-03 0,15133758 ! cobalt ion transport GO:0006824 9 5 0,000 7,27E-03 0,1500216 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 7,27E-03 0,14872831 ! SMAD protein complex assembly GO:0007183 10 5 0,000 7,27E-03 0,14745713 ! phospholipid dephosphorylation GO:0046839 7 5 0,000 7,27E-03 0,14620749 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 7,27E-03 0,14497886 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 7,27E-03 0,1437707 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 7,27E-03 0,14258251 ! adaptation of signaling pathway GO:0022401 9 5 0,000 7,27E-03 0,1414138 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! cardiac muscle cell proliferation GO:0060038 7 5 0,000 7,27E-03 0,1402641 GO:0014855|striated muscle cell proliferation, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 7,27E-03 0,13913294 ! negative regulation of gene-specific transcription GO:0032582 10 5 0,000 7,27E-03 0,13801987 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 7,27E-03 0,13692448 ! negative regulation of histone modification GO:0031057 7 5 0,000 7,27E-03 0,13584633 ! malate metabolic process GO:0006108 8 5 0,000 7,27E-03 0,13478503 ! positive regulation of histone modification GO:0031058 6 5 0,000 7,27E-03 0,13374019 ! transcription from mitochondrial promoter GO:0006390 8 5 0,000 7,27E-03 0,13271142 ! clathrin coat assembly GO:0048268 11 5 0,000 7,27E-03 0,13169835 ! Notch receptor processing GO:0007220 8 5 0,000 7,27E-03 0,13070064 ! phototransduction, visible light GO:0007603 7 5 0,000 7,27E-03 0,12971793 ! regulation of dopamine uptake GO:0051584 9 5 0,000 7,27E-03 0,12874988 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 7,27E-03 0,12779618 ! mating behavior GO:0007617 6 5 0,000 7,27E-03 0,1268565 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 7,27E-03 0,12593054 ! copulation GO:0007620 8 5 0,000 7,27E-03 0,125018 ! protein maturation by protein folding GO:0022417 13 5 0,000 7,27E-03 0,12411859 ! embryonic hemopoiesis GO:0035162 13 5 0,000 7,27E-03 0,12323203 ! regulation of potassium ion transport GO:0043266 9 5 0,000 7,27E-03 0,12235804 ! apoptotic cell clearance GO:0043277 14 5 0,000 7,27E-03 0,12149637 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 9 5 0,000 7,27E-03 0,12064674 ! lipoprotein particle clearance GO:0034381 9 5 0,000 7,27E-03 0,11980892 ! fructose 1,6-bisphosphate metabolic process GO:0030388 8 5 0,000 7,27E-03 0,11898265 ! regulation of smooth muscle cell apoptosis GO:0034391 8 5 0,000 7,27E-03 0,1181677 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 7,27E-03 0,11736384 GO:0046329|negative regulation of JNK cascade, ! oocyte maturation GO:0001556 6 5 0,000 7,27E-03 0,11657084 ! response to axon injury GO:0048678 8 5 0,000 7,27E-03 0,11578848 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 7,27E-03 0,11501656 ! response to protozoan GO:0001562 10 5 0,000 7,27E-03 0,11425486 ! negative regulation of heart contraction GO:0045822 12 5 0,000 7,27E-03 0,11350318 ! lymph vessel development GO:0001945 8 5 0,000 7,27E-03 0,11276133 ! regulation of activin receptor signaling pathway GO:0032925 11 5 0,000 7,27E-03 0,11202912 ! endochondral ossification GO:0001958 13 5 0,000 7,27E-03 0,11130635 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 7,27E-03 0,11059285 ! single strand break repair GO:0000012 5 5 0,000 7,27E-03 0,10988843 ! parathyroid gland development GO:0060017 8 5 0,000 7,27E-03 0,10919294 ! anagen GO:0042640 7 5 0,000 7,27E-03 0,10850619 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 7,27E-03 0,10782803 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 7,27E-03 0,10715829 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 7,27E-03 0,10649681 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 8 5 0,000 7,27E-03 0,10584346 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 8 5 0,000 7,27E-03 0,10519807 ! smooth muscle tissue development GO:0048745 14 5 0,000 7,27E-03 0,10456051 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 7,27E-03 0,10393063 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 7,27E-03 0,10330829 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 7,27E-03 0,10269336 ! cardiac muscle fiber development GO:0048739 8 5 0,000 7,27E-03 0,1020857 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 7,27E-03 0,1014852 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 8 5 0,000 7,27E-03 0,10089172 ! neutrophil mediated immunity GO:0002446 6 5 0,000 7,27E-03 0,10030514 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 7,27E-03 0,09972534 ! regulation of oligodendrocyte differentiation GO:0048713 15 5 0,000 7,27E-03 0,09915221 GO:0048715|negative regulation of oligodendrocyte differentiation, ! mitochondrion localization, microtubule-mediated GO:0034643 9 5 0,000 7,27E-03 0,09858562 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! negative regulation of RNA splicing GO:0033119 6 5 0,000 7,27E-03 0,09802548 ! ionotropic glutamate receptor signaling pathway GO:0035235 10 5 0,000 7,27E-03 0,09747166 ! positive regulation of isotype switching to IgG isotypes GO:0048304 8 5 0,000 7,27E-03 0,09692407 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 7,27E-03 0,09638259 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 9 5 0,000 7,27E-03 0,09584713 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 7,27E-03 0,09531759 ! tyrosine catabolic process GO:0006572 7 5 0,000 7,27E-03 0,09479387 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 7,27E-03 0,09427587 ! proline biosynthetic process GO:0006561 6 5 0,000 7,27E-03 0,0937635 ! L-serine biosynthetic process GO:0006564 6 5 0,000 7,27E-03 0,09325667 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 7,27E-03 0,09275529 ! polyol catabolic process GO:0046174 7 5 0,000 7,27E-03 0,09225927 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 7,27E-03 0,09176853 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 7,27E-03 0,09128298 ! sister chromatid cohesion GO:0007062 10 5 0,000 7,27E-03 0,09080255 ! response to ATP GO:0033198 6 5 0,000 7,27E-03 0,09032714 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 9 5 0,000 7,27E-03 0,08985669 ! positive regulation of stress fiber formation GO:0051496 15 5 0,000 7,27E-03 0,08939111 ! neutrophil activation GO:0042119 6 5 0,000 7,27E-03 0,08893033 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 7,27E-03 0,08847428 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 7,27E-03 0,08802288 ! response to food GO:0032094 5 5 0,000 7,27E-03 0,08757606 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 7,27E-03 0,08713376 GO:0043088|regulation of Cdc42 GTPase activity, ! positive regulation of transporter activity GO:0032411 5 5 0,000 7,27E-03 0,0866959 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 8 5 0,000 7,27E-03 0,08626242 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 7,27E-03 0,08583325 ! paraxial mesoderm development GO:0048339 9 5 0,000 7,27E-03 0,08540834 ! forebrain neuron development GO:0021884 7 5 0,000 7,27E-03 0,08498761 ! melanosome organization GO:0032438 7 5 0,000 7,27E-03 0,084571 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 7,27E-03 0,08415846 ! virus-infected cell apoptosis GO:0006926 8 5 0,000 7,27E-03 0,08374992 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 7,27E-03 0,08334533 ! positive regulation of neuroblast proliferation GO:0002052 9 5 0,000 7,27E-03 0,08294463 ! mesodermal cell fate determination GO:0007500 7 5 0,000 7,27E-03 0,08254777 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 7,27E-03 0,08215469 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 8 5 0,000 7,27E-03 0,08176533 ! nucleoside salvage GO:0043174 7 5 0,000 7,27E-03 0,08137964 GO:0006166|purine ribonucleoside salvage, ! lipid glycosylation GO:0030259 6 5 0,000 7,27E-03 0,08099758 ! attachment of GPI anchor to protein GO:0016255 10 5 0,000 7,27E-03 0,08061908 ! negative regulation of platelet activation GO:0010544 8 5 0,000 7,27E-03 0,08024411 GO:0010543|regulation of platelet activation, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 7,27E-03 0,07987261 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 7,27E-03 0,07950453 ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 7,27E-03 0,07913983 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of fatty acid metabolic process GO:0045923 6 5 0,000 7,27E-03 0,07877847 ! early endosome to late endosome transport GO:0045022 11 5 0,000 7,27E-03 0,07842038 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 6 5 0,000 7,27E-03 0,07806554 ! depyrimidination GO:0045008 8 5 0,000 7,27E-03 0,07771389 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 7,27E-03 0,0773654 ! 5S class rRNA transcription GO:0042791 8 5 0,000 7,27E-03 0,07702002 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 5 0,000 7,27E-03 0,07667771 ! neuronal ion channel clustering GO:0045161 8 5 0,000 7,27E-03 0,07633842 ! sodium ion homeostasis GO:0055078 6 5 0,000 7,27E-03 0,07600213 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 7,27E-03 0,07566879 ! monocyte differentiation GO:0030224 7 5 0,000 7,27E-03 0,07533836 ! negative regulation of peptide secretion GO:0002792 8 5 0,000 7,27E-03 0,0750108 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 6 5 0,000 7,27E-03 0,07468608 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 7,27E-03 0,07436416 ! response to UV-C GO:0010225 7 5 0,000 7,27E-03 0,074045 ! protein targeting to vacuole GO:0006623 6 5 0,000 7,27E-03 0,07372856 ! activated T cell proliferation GO:0050798 7 5 0,000 7,27E-03 0,07341483 ! negative regulation of alpha-beta T cell activation GO:0046636 7 5 0,000 7,27E-03 0,07310375 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! regulation of alpha-beta T cell proliferation GO:0046640 13 5 0,000 7,27E-03 0,07279529 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 7,27E-03 0,07248943 ! regulation of integrin biosynthetic process GO:0045113 9 5 0,000 7,27E-03 0,07218613 ! regulation of killing of cells of another organism GO:0051709 6 5 0,000 7,27E-03 0,07188535 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 7,27E-03 0,07158707 ! lymphoid progenitor cell differentiation GO:0002320 12 5 0,000 7,27E-03 0,07129126 ! positive regulation of T cell cytokine production GO:0002726 9 5 0,000 7,27E-03 0,07099788 GO:0032743|positive regulation of interleukin-2 production, ! L-ascorbic acid metabolic process GO:0019852 7 5 0,000 7,27E-03 0,0707069 ! base-excision repair, DNA ligation GO:0006288 5 5 0,000 7,27E-03 0,0704183 ! response to cadmium ion GO:0046686 8 5 0,000 7,27E-03 0,07013205 ! melanosome transport GO:0032402 8 5 0,000 7,27E-03 0,06984811 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 7,27E-03 0,06956647 ! regulation of acetylcholine secretion GO:0014056 10 5 0,000 7,27E-03 0,06928708 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 7,27E-03 0,06900994 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 7,27E-03 0,068735 ! positive T cell selection GO:0043368 10 5 0,000 7,27E-03 0,06846224 ! purine deoxyribonucleotide catabolic process GO:0009155 6 5 0,000 7,27E-03 0,06819164 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 7,27E-03 0,06792317 ! regulation of interleukin-1 production GO:0032652 8 5 0,000 7,27E-03 0,0676568 ! ribosomal subunit assembly GO:0042257 5 5 0,000 7,27E-03 0,06739252 ! base conversion or substitution editing GO:0016553 6 5 0,000 7,27E-03 0,06713029 ! regulation of chondrocyte differentiation GO:0032330 9 5 0,000 7,27E-03 0,06687009 ! negative regulation of monooxygenase activity GO:0032769 10 5 0,000 7,27E-03 0,06661191 ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 7,27E-03 0,06635571 ! positive regulation of interleukin-12 production GO:0032735 5 5 0,000 7,27E-03 0,06610147 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 7,27E-03 0,06584918 ! histone demethylation GO:0016577 10 5 0,000 7,27E-03 0,0655988 ! mitotic recombination GO:0006312 10 5 0,000 7,27E-03 0,06535032 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 5 0,000 7,27E-03 0,06510371 ! regulation of sterol transport GO:0032371 7 5 0,000 7,27E-03 0,06485896 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 7,27E-03 0,06461605 ! sympathetic nervous system development GO:0048485 13 5 0,000 7,27E-03 0,06437494 ! enteric nervous system development GO:0048484 9 5 0,000 7,27E-03 0,06413563 ! oxygen homeostasis GO:0032364 8 5 0,000 7,27E-03 0,06389809 ! establishment of planar polarity GO:0001736 7 5 0,000 7,27E-03 0,0636623 ! lymphocyte costimulation GO:0031294 12 5 0,000 7,27E-03 0,06342825 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 6 5 0,000 7,27E-03 0,06319591 ! transcription termination GO:0006353 8 5 0,000 7,27E-03 0,06296527 ! plasminogen activation GO:0031639 5 5 0,000 7,27E-03 0,06273631 ! B cell homeostasis GO:0001782 12 5 0,000 7,27E-03 0,062509 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 7,27E-03 0,06228334 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 7,27E-03 0,0620593 ! regulation of hair follicle development GO:0051797 9 5 0,000 7,27E-03 0,06183686 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 7,27E-03 0,06161601 ! apical protein localization GO:0045176 8 5 0,000 7,27E-03 0,06139674 ! definitive hemopoiesis GO:0060216 5 5 0,000 7,27E-03 0,06117902 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 7,27E-03 0,06096284 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 7,27E-03 0,06074818 ! glucocorticoid biosynthetic process GO:0006704 6 5 0,000 7,27E-03 0,06053503 ! regulation of keratinocyte differentiation GO:0045616 7 5 0,000 7,27E-03 0,06032337 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 7,27E-03 0,06011318 ! regulation of centrosome duplication GO:0010824 6 5 0,000 7,27E-03 0,05990446 ! disaccharide metabolic process GO:0005984 9 5 0,000 7,27E-03 0,05969718 ! galactolipid metabolic process GO:0019374 8 5 0,000 7,27E-03 0,05949132 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 7,27E-03 0,05928689 GO:0033015|tetrapyrrole catabolic process, ! positive regulation of T cell mediated cytotoxicity GO:0001916 11 5 0,000 7,27E-03 0,05908385 ! determination of adult lifespan GO:0008340 8 5 0,000 7,27E-03 0,0588822 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 7,27E-03 0,05868192 ! ectodermal gut morphogenesis GO:0048567 6 5 0,000 7,27E-03 0,058483 GO:0007439|ectodermal gut development, ! somatic stem cell maintenance GO:0035019 14 5 0,000 7,27E-03 0,05828542 ! T cell activation during immune response GO:0002286 9 5 0,000 7,27E-03 0,05808917 ! negative regulation of fibrinolysis GO:0051918 9 5 0,000 7,27E-03 0,05789424 ! negative regulation of lipase activity GO:0060192 7 5 0,000 7,27E-03 0,05770062 ! establishment of apical/basal cell polarity GO:0035089 7 5 0,000 7,27E-03 0,05750828 ! neural plate development GO:0001840 7 5 0,000 7,27E-03 0,05731722 ! regulation of sensory perception GO:0051931 6 5 0,000 7,27E-03 0,05712743 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 10 5 0,000 7,27E-03 0,05693889 ! regulation of histone acetylation GO:0035065 7 5 0,000 7,27E-03 0,05675159 ! sensory cilium assembly GO:0035058 6 5 0,000 7,27E-03 0,05656552 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 14 5 0,000 7,27E-03 0,05638067 ! diacylglycerol metabolic process GO:0046339 8 5 0,000 7,27E-03 0,05619702 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 7,27E-03 0,05601456 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 11 5 0,000 7,27E-03 0,05583328 ! negative regulation of smooth muscle contraction GO:0045986 10 5 0,000 7,27E-03 0,05565317 ! receptor biosynthetic process GO:0032800 6 5 0,000 7,27E-03 0,05547423 ! penetration of zona pellucida GO:0007341 9 5 0,000 7,27E-03 0,05529642 ! drug metabolic process GO:0017144 5 5 0,000 7,27E-03 0,05511976 ! protein amino acid prenylation GO:0018346 9 5 0,000 7,27E-03 0,05494422 ! organ regeneration GO:0031100 7 5 0,000 7,27E-03 0,05476979 ! carnitine metabolic process GO:0009437 5 5 0,000 7,27E-03 0,05459647 GO:0006577|betaine metabolic process, ! regulation of GTPase activity GO:0043087 149 90 1,000 7,595E-03 0,05685165 ! regulation of cell adhesion GO:0030155 187 94 1,000 8,259E-03 0,06162987 ! tRNA transcription GO:0009304 11 6 0,000 8,718E-03 0,06485398 ! negative regulation of S phase of mitotic cell cycle GO:0045749 13 6 0,000 8,718E-03 0,06465131 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 8,718E-03 0,0644499 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 8 6 0,000 8,718E-03 0,06424975 ! regulation of helicase activity GO:0051095 11 6 0,000 8,718E-03 0,06405083 ! regulation of cGMP metabolic process GO:0030823 8 6 0,000 8,718E-03 0,06385314 ! sleep GO:0030431 13 6 0,000 8,718E-03 0,06365667 ! positive regulation of axon extension GO:0045773 10 6 0,000 8,718E-03 0,06346141 ! negative regulation of small GTPase mediated signal transduction GO:0051058 11 6 0,000 8,718E-03 0,06326733 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 8,718E-03 0,06307445 ! forebrain regionalization GO:0021871 7 6 0,000 8,718E-03 0,06288273 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 8,718E-03 0,06269218 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 8,718E-03 0,06250277 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 8,718E-03 0,06231451 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 8,718E-03 0,06212738 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 18 6 0,000 8,718E-03 0,06194137 ! regulation of protein export from nucleus GO:0046825 8 6 0,000 8,718E-03 0,06175647 ! neuron adhesion GO:0007158 9 6 0,000 8,718E-03 0,06157267 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 8,718E-03 0,06138996 ! signal peptide processing GO:0006465 8 6 0,000 8,718E-03 0,06120834 ! embryonic camera-type eye development GO:0031076 11 6 0,000 8,718E-03 0,06102778 GO:0048596|embryonic camera-type eye morphogenesis, ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 8,718E-03 0,06084829 ! glucocorticoid receptor signaling pathway GO:0042921 11 6 0,000 8,718E-03 0,06066985 GO:0031958|corticosteroid receptor signaling pathway, ! citrate metabolic process GO:0006101 10 6 0,000 8,718E-03 0,06049245 ! fibril organization GO:0043206 13 6 0,000 8,718E-03 0,06031609 ! regulation of mitochondrial membrane permeability GO:0046902 12 6 0,000 8,718E-03 0,06014075 ! neurofilament cytoskeleton organization GO:0060052 10 6 0,000 8,718E-03 0,05996643 ! posttranscriptional gene silencing by RNA GO:0035194 14 6 0,000 8,718E-03 0,05979312 GO:0016441|posttranscriptional gene silencing, ! behavioral response to pain GO:0048266 10 6 0,000 8,718E-03 0,0596208 ! protein refolding GO:0042026 13 6 0,000 8,718E-03 0,05944948 ! metabotropic glutamate receptor signaling pathway GO:0007216 8 6 0,000 8,718E-03 0,05927914 ! rhythmic behavior GO:0007622 14 6 0,000 8,718E-03 0,05910977 ! glial cell fate commitment GO:0021781 17 6 0,000 8,718E-03 0,05894136 ! erythrocyte maturation GO:0043249 7 6 0,000 8,718E-03 0,05877392 ! sensory perception of temperature stimulus GO:0050951 12 6 0,000 8,718E-03 0,05860742 ! protein amino acid dealkylation GO:0008214 12 6 0,000 8,718E-03 0,05844186 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 8,718E-03 0,05827723 ! regulation of odontogenesis GO:0042481 8 6 0,000 8,718E-03 0,05811353 ! mechanosensory behavior GO:0007638 8 6 0,000 8,718E-03 0,05795075 ! ovulation from ovarian follicle GO:0001542 7 6 0,000 8,718E-03 0,05778888 ! negative regulation of endocytosis GO:0045806 8 6 0,000 8,718E-03 0,05762791 ! response to interferon-gamma GO:0034341 12 6 0,000 8,718E-03 0,05746783 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 8,718E-03 0,05730864 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 9 6 0,000 8,718E-03 0,05715033 ! negative regulation of viral genome replication GO:0045071 8 6 0,000 8,718E-03 0,05699289 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 6 6 0,000 8,718E-03 0,05683631 ! spinal cord dorsal/ventral patterning GO:0021513 8 6 0,000 8,718E-03 0,0566806 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 17 6 0,000 8,718E-03 0,05652573 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 11 6 0,000 8,718E-03 0,05637171 ! cGMP-mediated signaling GO:0019934 11 6 0,000 8,718E-03 0,05621853 ! activation of MAPKKK activity GO:0000185 11 6 0,000 8,718E-03 0,05606617 ! inositol phosphate-mediated signaling GO:0048016 10 6 0,000 8,718E-03 0,05591464 ! protein lipoylation GO:0009249 10 6 0,000 8,718E-03 0,05576393 ! pigment granule organization GO:0048753 11 6 0,000 8,718E-03 0,05561403 ! drug transport GO:0015893 6 6 0,000 8,718E-03 0,05546493 ! transepithelial chloride transport GO:0030321 10 6 0,000 8,718E-03 0,05531663 GO:0070633|transepithelial transport, ! cysteine metabolic process GO:0006534 8 6 0,000 8,718E-03 0,05516912 ! negative regulation of survival gene product expression GO:0008634 9 6 0,000 8,718E-03 0,05502239 ! regulation of defense response to virus by host GO:0050691 7 6 0,000 8,718E-03 0,05487644 ! glutamate catabolic process GO:0006538 11 6 0,000 8,718E-03 0,05473126 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 8,718E-03 0,05458686 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 8,718E-03 0,05444321 ! adenohypophysis development GO:0021984 10 6 0,000 8,718E-03 0,05430031 ! response to pH GO:0009268 10 6 0,000 8,718E-03 0,05415816 ! hyperosmotic response GO:0006972 9 6 0,000 8,718E-03 0,05401676 ! microtubule nucleation GO:0007020 10 6 0,000 8,718E-03 0,05387609 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 6 0,000 8,718E-03 0,05373615 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 6 0,000 8,718E-03 0,05359694 ! melanin biosynthetic process from tyrosine GO:0006583 9 6 0,000 8,718E-03 0,05345844 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 8,718E-03 0,05332067 ! vascular smooth muscle contraction GO:0014829 11 6 0,000 8,718E-03 0,05318359 ! regulation of retinoic acid receptor signaling pathway GO:0048385 13 6 0,000 8,718E-03 0,05304723 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 8,718E-03 0,05291156 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 8,718E-03 0,05277658 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 8,718E-03 0,05264229 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 8,718E-03 0,05250868 ! purine salvage GO:0043101 9 6 0,000 8,718E-03 0,05237574 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 8,718E-03 0,05224348 ! peptidyl-threonine phosphorylation GO:0018107 16 6 0,000 8,718E-03 0,05211188 ! nucleoside transport GO:0015858 7 6 0,000 8,718E-03 0,05198095 ! organic alcohol transport GO:0015850 9 6 0,000 8,718E-03 0,05185067 ! T cell mediated immunity GO:0002456 12 6 0,000 8,718E-03 0,05172105 ! folic acid transport GO:0015884 11 6 0,000 8,718E-03 0,05159207 ! male sex determination GO:0030238 11 6 0,000 8,718E-03 0,05146373 ! carnitine transport GO:0015879 8 6 0,000 8,718E-03 0,05133603 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 8,718E-03 0,05120896 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 8,718E-03 0,05108251 ! negative regulation of DNA recombination GO:0045910 10 6 0,000 8,718E-03 0,05095669 ! positive regulation of exocytosis GO:0045921 9 6 0,000 8,718E-03 0,05083149 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 8,718E-03 0,05070691 ! parturition GO:0007567 13 6 0,000 8,718E-03 0,05058293 ! determination of anterior/posterior axis, embryo GO:0008595 10 6 0,000 8,718E-03 0,05045956 GO:0007351|tripartite regional subdivision, ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 8,718E-03 0,05033678 ! lipopolysaccharide biosynthetic process GO:0009103 6 6 0,000 8,718E-03 0,05021461 ! regulation of centrosome cycle GO:0046605 8 6 0,000 8,718E-03 0,05009302 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 8,718E-03 0,04997202 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 8,718E-03 0,04985161 ! regulation of cholesterol biosynthetic process GO:0045540 8 6 0,000 8,718E-03 0,04973177 ! homeostasis of number of cells within a tissue GO:0048873 10 6 0,000 8,718E-03 0,04961251 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 8,718E-03 0,04949382 ! negative regulation of gliogenesis GO:0014014 17 6 0,000 8,718E-03 0,0493757 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 10 6 0,000 8,718E-03 0,04925814 ! neural nucleus development GO:0048857 12 6 0,000 8,718E-03 0,04914114 ! forebrain morphogenesis GO:0048853 14 6 0,000 8,718E-03 0,04902469 ! hyaluronan metabolic process GO:0030212 7 6 0,000 8,718E-03 0,04890879 ! purine base biosynthetic process GO:0009113 14 6 0,000 8,718E-03 0,04879344 ! interaction with symbiont GO:0051702 9 6 0,000 8,718E-03 0,04867863 ! regulation of dendrite development GO:0050773 13 6 0,000 8,718E-03 0,04856436 ! anterograde axon cargo transport GO:0008089 9 6 0,000 8,718E-03 0,04845063 ! positive regulation of organ growth GO:0046622 7 6 0,000 8,718E-03 0,04833743 ! eating behavior GO:0042755 6 6 0,000 8,718E-03 0,04822475 ! regulation of T cell cytokine production GO:0002724 11 6 0,000 8,718E-03 0,0481126 ! transcription-coupled nucleotide-excision repair GO:0006283 7 6 0,000 8,718E-03 0,04800097 ! response to copper ion GO:0046688 9 6 0,000 8,718E-03 0,04788986 ! negative regulation of lymphocyte mediated immunity GO:0002707 13 6 0,000 8,718E-03 0,04777926 GO:0002704|negative regulation of leukocyte mediated immunity, ! response to exogenous dsRNA GO:0043330 8 6 0,000 8,718E-03 0,04766917 ! establishment of melanosome localization GO:0032401 9 6 0,000 8,718E-03 0,04755958 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 8,718E-03 0,0474505 ! negative regulation of protein kinase B signaling cascade GO:0051898 12 6 0,000 8,718E-03 0,04734192 ! positive regulation of B cell differentiation GO:0045579 10 6 0,000 8,718E-03 0,04723383 ! regulation of dopamine secretion GO:0014059 14 6 0,000 8,718E-03 0,04712624 ! nucleoside catabolic process GO:0009164 7 6 0,000 8,718E-03 0,04701913 ! hair follicle maturation GO:0048820 8 6 0,000 8,718E-03 0,04691251 ! cranial nerve morphogenesis GO:0021602 7 6 0,000 8,718E-03 0,04680638 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 8,718E-03 0,04670072 ! positive regulation of interleukin-5 production GO:0032754 9 6 0,000 8,718E-03 0,04659554 GO:0032736|positive regulation of interleukin-13 production, ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 8,718E-03 0,04649083 ! rhombomere development GO:0021546 6 6 0,000 8,718E-03 0,04638659 ! G2 phase GO:0051319 15 6 0,000 8,718E-03 0,04628281 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 10 6 0,000 8,718E-03 0,0461795 GO:0050000|chromosome localization, ! regulation of mast cell activation GO:0033003 7 6 0,000 8,718E-03 0,04607666 ! muscle cell proliferation GO:0033002 9 6 0,000 8,718E-03 0,04597426 ! membrane to membrane docking GO:0022614 12 6 0,000 8,718E-03 0,04587232 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 10 6 0,000 8,718E-03 0,04577084 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 12 6 0,000 8,718E-03 0,0456698 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 6 0,000 8,718E-03 0,0455692 ! receptor internalization GO:0031623 9 6 0,000 8,718E-03 0,04546905 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 8,718E-03 0,04536934 GO:0031272|regulation of pseudopodium assembly, ! regulation of respiratory burst GO:0060263 9 6 0,000 8,718E-03 0,04527006 ! coenzyme A metabolic process GO:0015936 9 6 0,000 8,718E-03 0,04517122 ! myeloid dendritic cell activation GO:0001773 11 6 0,000 8,718E-03 0,04507281 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 12 6 0,000 8,718E-03 0,04497482 ! peptidyl-histidine modification GO:0018202 10 6 0,000 8,718E-03 0,04487726 ! axonal fasciculation GO:0007413 10 6 0,000 8,718E-03 0,04478013 ! regulation of muscle cell apoptosis GO:0010660 9 6 0,000 8,718E-03 0,04468341 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 8,718E-03 0,04458711 GO:0015991|ATP hydrolysis coupled proton transport, ! midbrain development GO:0030901 7 6 0,000 8,718E-03 0,04449122 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 8,718E-03 0,04439575 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 8,718E-03 0,04430068 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 7 6 0,000 8,718E-03 0,04420602 ! progesterone metabolic process GO:0042448 8 6 0,000 8,718E-03 0,04411177 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 8,718E-03 0,04401791 ! glycolipid catabolic process GO:0019377 14 6 0,000 8,718E-03 0,04392445 GO:0046479|glycosphingolipid catabolic process, ! nonprotein amino acid metabolic process GO:0019794 10 6 0,000 8,718E-03 0,04383139 ! negative regulation of axon extension GO:0030517 13 6 0,000 8,718E-03 0,04373873 ! removal of superoxide radicals GO:0019430 10 6 0,000 8,718E-03 0,04364645 ! triglyceride catabolic process GO:0019433 8 6 0,000 8,718E-03 0,04355456 ! protein modification by small protein removal GO:0070646 10 6 0,000 8,718E-03 0,04346306 GO:0016579|protein deubiquitination, ! adult feeding behavior GO:0008343 6 6 0,000 8,718E-03 0,04337195 ! regulation of Rac protein signal transduction GO:0035020 9 6 0,000 8,718E-03 0,04328121 ! glial cell migration GO:0008347 11 6 0,000 8,718E-03 0,04319085 ! blastocyst growth GO:0001832 17 6 0,000 8,718E-03 0,04310087 ! pigment granule transport GO:0051904 12 6 0,000 8,718E-03 0,04301126 ! lymphocyte activation during immune response GO:0002285 10 6 0,000 8,718E-03 0,04292203 ! cerebellar cortex formation GO:0021697 9 6 0,000 8,718E-03 0,04283316 ! catecholamine transport GO:0051937 7 6 0,000 8,718E-03 0,04274467 ! hemopoietic progenitor cell differentiation GO:0002244 14 6 0,000 8,718E-03 0,04265653 ! positive regulation of actin filament bundle formation GO:0032233 16 6 0,000 8,718E-03 0,04256876 ! organ or tissue specific immune response GO:0002251 7 6 0,000 8,718E-03 0,04248135 ! positive regulation of smooth muscle contraction GO:0045987 10 6 0,000 8,718E-03 0,0423943 ! spindle assembly GO:0051225 6 6 0,000 8,718E-03 0,0423076 ! ensheathment of axons in the peripheral nervous system GO:0032292 15 6 0,000 8,718E-03 0,04222126 GO:0022011|myelination in the peripheral nervous system, ! protein prenylation GO:0018342 10 6 0,000 8,718E-03 0,04213527 ! negative regulation of synaptic transmission GO:0050805 12 6 0,000 8,718E-03 0,04204963 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 8,718E-03 0,04196434 ! NAD biosynthetic process GO:0009435 9 6 0,000 8,718E-03 0,04187939 ! positive regulation of coagulation GO:0050820 11 6 0,000 8,718E-03 0,04179478 ! cellular anion homeostasis GO:0030002 9 6 0,000 8,718E-03 0,04171052 GO:0055081|anion homeostasis, ! regulation of binding GO:0051098 164 99 1,000 9,125E-03 0,04356727 ! electron transport chain GO:0022900 135 99 1,000 9,125E-03 0,04347979 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,01016414 0,0483357 ! behavioral response to cocaine GO:0048148 13 7 0,000 0,01016414 0,04823903 ! autophagic vacuole formation GO:0000045 12 7 0,000 0,01016414 0,04814274 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01016414 0,04804684 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 10 7 0,000 0,01016414 0,04795132 ! chaperone mediated protein folding requiring cofactor GO:0051085 9 7 0,000 0,01016414 0,04785618 ! prostate gland development GO:0030850 11 7 0,000 0,01016414 0,04776141 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01016414 0,04766702 ! regulation of hormone biosynthetic process GO:0046885 12 7 0,000 0,01016414 0,047573 ! synaptonemal complex assembly GO:0007130 11 7 0,000 0,01016414 0,04747936 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 10 7 0,000 0,01016414 0,04738608 ! male meiosis GO:0007140 10 7 0,000 0,01016414 0,04729316 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01016414 0,04720061 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! reproductive behavior GO:0019098 12 7 0,000 0,01016414 0,04710842 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01016414 0,0470166 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01016414 0,04692512 ! oligopeptide transport GO:0006857 11 7 0,000 0,01016414 0,04683401 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01016414 0,04674324 GO:0051923|sulfation, ! N-terminal protein amino acid acetylation GO:0006474 9 7 0,000 0,01016414 0,04665283 ! establishment of tissue polarity GO:0007164 10 7 0,000 0,01016414 0,04656277 ! receptor guanylyl cyclase signaling pathway GO:0007168 7 7 0,000 0,01016414 0,04647305 ! RNA methylation GO:0001510 11 7 0,000 0,01016414 0,04638368 ! negative regulation of cell-cell adhesion GO:0022408 20 7 0,000 0,01016414 0,04629465 ! positive regulation of cell-cell adhesion GO:0022409 17 7 0,000 0,01016414 0,04620596 ! pericardium development GO:0060039 9 7 0,000 0,01016414 0,04611762 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01016414 0,04602961 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01016414 0,04594193 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01016414 0,04585459 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01016414 0,04576758 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01016414 0,0456809 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01016414 0,04559454 ! opsonization GO:0008228 9 7 0,000 0,01016414 0,04550852 ! tachykinin receptor signaling pathway GO:0007217 12 7 0,000 0,01016414 0,04542281 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01016414 0,04533743 ! regulation of dopamine metabolic process GO:0042053 10 7 0,000 0,01016414 0,04525237 GO:0042069|regulation of catecholamine metabolic process, ! glucocorticoid metabolic process GO:0008211 8 7 0,000 0,01016414 0,04516763 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01016414 0,0450832 ! chemosensory behavior GO:0007635 9 7 0,000 0,01016414 0,04499909 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01016414 0,04491529 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01016414 0,04483181 ! leukocyte degranulation GO:0043299 11 7 0,000 0,01016414 0,04474863 ! positive regulation of glycolysis GO:0045821 13 7 0,000 0,01016414 0,04466577 ! DNA ligation during DNA repair GO:0051103 10 7 0,000 0,01016414 0,0445832 ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01016414 0,04450095 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01016414 0,04441899 ! lipopolysaccharide metabolic process GO:0008653 7 7 0,000 0,01016414 0,04433734 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01016414 0,04425599 ! spinal cord patterning GO:0021511 9 7 0,000 0,01016414 0,04417493 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01016414 0,04409417 ! thymic T cell selection GO:0045061 15 7 0,000 0,01016414 0,04401371 ! regulation of transcriptional preinitiation complex assembly GO:0045898 11 7 0,000 0,01016414 0,04393354 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01016414 0,04385366 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01016414 0,04377407 ! ovulation GO:0030728 8 7 0,000 0,01016414 0,04369477 ! regulation of isotype switching to IgG isotypes GO:0048302 11 7 0,000 0,01016414 0,04361576 ! histidine metabolic process GO:0006547 7 7 0,000 0,01016414 0,04353703 GO:0009075|histidine family amino acid metabolic process, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 7 0,000 0,01016414 0,04345858 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01016414 0,04338042 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! deoxyribonucleotide biosynthetic process GO:0009263 9 7 0,000 0,01016414 0,04330254 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 0,01016414 0,04322493 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! ER overload response GO:0006983 8 7 0,000 0,01016414 0,04314761 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01016414 0,04307056 ! endosome organization GO:0007032 10 7 0,000 0,01016414 0,04299379 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01016414 0,04291728 GO:0021940|positive regulation of granule cell precursor proliferation, ! positive regulation of interleukin-8 biosynthetic process GO:0045416 8 7 0,000 0,01016414 0,04284105 ! phasic smooth muscle contraction GO:0014821 13 7 0,000 0,01016414 0,04276509 ! urea metabolic process GO:0019627 9 7 0,000 0,01016414 0,0426894 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 14 7 0,000 0,01016414 0,04261398 ! vesicle fusion GO:0006906 15 7 0,000 0,01016414 0,04253882 ! positive regulation of insulin secretion GO:0032024 9 7 0,000 0,01016414 0,04246393 ! maintenance of protein location in nucleus GO:0051457 17 7 0,000 0,01016414 0,0423893 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01016414 0,04231494 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 10 7 0,000 0,01016414 0,04224083 GO:0046464|acylglycerol catabolic process, ! asymmetric protein localization GO:0008105 10 7 0,000 0,01016414 0,04216698 ! organ growth GO:0035265 13 7 0,000 0,01016414 0,04209339 ! positive regulation of mesenchymal cell proliferation GO:0002053 10 7 0,000 0,01016414 0,04202006 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01016414 0,04194698 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 7 0,000 0,01016414 0,04187416 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 8 7 0,000 0,01016414 0,04180158 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! retinol metabolic process GO:0042572 9 7 0,000 0,01016414 0,04172926 ! positive regulation of mitotic cell cycle GO:0045931 13 7 0,000 0,01016414 0,04165719 ! rRNA modification GO:0000154 12 7 0,000 0,01016414 0,04158537 ! negative regulation of translational initiation GO:0045947 9 7 0,000 0,01016414 0,04151379 ! DNA damage response, signal transduction resulting in transcription GO:0042772 14 7 0,000 0,01016414 0,04144246 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 20 7 0,000 0,01016414 0,04137138 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01016414 0,04130054 ! response to UV-B GO:0010224 11 7 0,000 0,01016414 0,04122994 ! astrocyte development GO:0014002 15 7 0,000 0,01016414 0,04115958 ! intermediate filament organization GO:0045109 12 7 0,000 0,01016414 0,04108946 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01016414 0,04101958 ! fibrinolysis GO:0042730 9 7 0,000 0,01016414 0,04094994 ! peptidyl-arginine modification GO:0018195 9 7 0,000 0,01016414 0,04088053 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 7 0,000 0,01016414 0,04081136 ! blastoderm segmentation GO:0007350 11 7 0,000 0,01016414 0,04074242 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01016414 0,04067372 ! DNA topological change GO:0006265 10 7 0,000 0,01016414 0,04060524 ! regulation of fat cell differentiation GO:0045598 10 7 0,000 0,01016414 0,040537 ! melanosome localization GO:0032400 10 7 0,000 0,01016414 0,04046898 ! enucleate erythrocyte differentiation GO:0043353 10 7 0,000 0,01016414 0,04040119 ! regulation of interleukin-5 production GO:0032674 10 7 0,000 0,01016414 0,04033363 ! glycosylceramide metabolic process GO:0006677 10 7 0,000 0,01016414 0,0402663 ! mast cell activation GO:0045576 10 7 0,000 0,01016414 0,04019919 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01016414 0,0401323 ! negative regulation of focal adhesion formation GO:0051895 16 7 0,000 0,01016414 0,04006564 ! gas homeostasis GO:0033483 12 7 0,000 0,01016414 0,03999919 ! negative regulation of T cell differentiation GO:0045581 9 7 0,000 0,01016414 0,03993297 ! phosphatidylinositol biosynthetic process GO:0006661 11 7 0,000 0,01016414 0,03986696 ! Schwann cell development GO:0014044 16 7 0,000 0,01016414 0,03980118 ! dendrite morphogenesis GO:0048813 12 7 0,000 0,01016414 0,03973561 ! regulation of interleukin-13 production GO:0032656 12 7 0,000 0,01016414 0,03967025 ! positive regulation of interleukin-4 production GO:0032753 10 7 0,000 0,01016414 0,03960511 ! molybdopterin cofactor biosynthetic process GO:0032324 10 7 0,000 0,01016414 0,03954019 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 11 7 0,000 0,01016414 0,03947547 ! neural tube patterning GO:0021532 8 7 0,000 0,01016414 0,03941097 ! histone ubiquitination GO:0016574 10 7 0,000 0,01016414 0,03934668 ! regulation of meiosis GO:0040020 12 7 0,000 0,01016414 0,0392826 GO:0051445|regulation of meiotic cell cycle, ! eye photoreceptor cell differentiation GO:0001754 14 7 0,000 0,01016414 0,03921872 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 12 7 0,000 0,01016414 0,03915505 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01016414 0,03909159 GO:0002714|positive regulation of B cell mediated immunity, ! mitochondrion morphogenesis GO:0070584 12 7 0,000 0,01016414 0,03902834 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01016414 0,03896529 ! regulation of cell division GO:0051302 9 7 0,000 0,01016414 0,03890244 ! regulation of inflammatory response to antigenic stimulus GO:0002861 14 7 0,000 0,01016414 0,0388398 ! neutrophil homeostasis GO:0001780 8 7 0,000 0,01016414 0,03877735 ! regulation of macrophage activation GO:0043030 12 7 0,000 0,01016414 0,03871511 ! negative regulation of nuclear division GO:0051784 18 7 0,000 0,01016414 0,03865307 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01016414 0,03859122 ! diuresis GO:0030146 11 7 0,000 0,01016414 0,03852957 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 9 7 0,000 0,01016414 0,03846812 ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01016414 0,03840687 ! thiamin metabolic process GO:0006772 8 7 0,000 0,01016414 0,03834581 ! positive regulation of leukocyte chemotaxis GO:0002690 15 7 0,000 0,01016414 0,03828494 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of epidermal cell differentiation GO:0045604 10 7 0,000 0,01016414 0,03822427 ! negative regulation of transmission of nerve impulse GO:0051970 13 7 0,000 0,01016414 0,03816379 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01016414 0,0381035 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01016414 0,0380434 ! lymph node development GO:0048535 9 7 0,000 0,01016414 0,03798349 ! anterior/posterior axis specification GO:0009948 11 7 0,000 0,01016414 0,03792376 ! negative regulation of viral reproduction GO:0048525 9 7 0,000 0,01016414 0,03786423 ! regulation of T cell mediated cytotoxicity GO:0001914 15 7 0,000 0,01016414 0,03780488 ! positive regulation of glucose import GO:0046326 7 7 0,000 0,01016414 0,03774572 GO:0010828|positive regulation of glucose transport, ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01016414 0,03768674 ! ATP catabolic process GO:0006200 10 7 0,000 0,01016414 0,03762795 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01016414 0,03756934 ! positive regulation of fibrinolysis GO:0051919 8 7 0,000 0,01016414 0,03751091 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01016414 0,03745266 ! negative regulation of calcium ion transport GO:0051926 8 7 0,000 0,01016414 0,03739459 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01016414 0,03733671 ! positive regulation of blood vessel endothelial cell migration GO:0043536 17 7 0,000 0,01016414 0,037279 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01016414 0,03722147 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01016414 0,03716412 ! muscle adaptation GO:0043500 12 7 0,000 0,01016414 0,03710694 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01016414 0,03704994 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 8 7 0,000 0,01016414 0,03699312 ! retina homeostasis GO:0001895 9 7 0,000 0,01016414 0,03693647 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01016414 0,03687999 ! regulation of growth hormone secretion GO:0060123 14 7 0,000 0,01016414 0,03682368 ! regulation of T cell receptor signaling pathway GO:0050856 12 7 0,000 0,01016414 0,03676755 ! positive regulation of microtubule polymerization GO:0031116 12 7 0,000 0,01016414 0,03671159 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01016414 0,0366558 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 8 0,000 0,011608 0,04179936 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 16 8 0,000 0,011608 0,04173602 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,011608 0,04167288 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,011608 0,04160993 ! oligosaccharide biosynthetic process GO:0009312 14 8 0,000 0,011608 0,04154717 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 8 0,000 0,011608 0,0414846 ! negative regulation of cellular catabolic process GO:0031330 10 8 0,000 0,011608 0,04142222 ! positive regulation of small GTPase mediated signal transduction GO:0051057 16 8 0,000 0,011608 0,04136002 GO:0046579|positive regulation of Ras protein signal transduction, ! generation of neurons in the forebrain GO:0021872 11 8 0,000 0,011608 0,04129802 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,011608 0,04123619 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,011608 0,04117455 ! neutral lipid catabolic process GO:0046461 11 8 0,000 0,011608 0,0411131 ! N-glycan processing GO:0006491 12 8 0,000 0,011608 0,04105183 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,011608 0,04099074 ! glycosaminoglycan catabolic process GO:0006027 11 8 0,000 0,011608 0,04092983 ! negative regulation of JAK-STAT cascade GO:0046426 18 8 0,000 0,011608 0,0408691 ! mRNA stabilization GO:0048255 16 8 0,000 0,011608 0,04080856 GO:0043489|RNA stabilization, ! induction of positive chemotaxis GO:0050930 16 8 0,000 0,011608 0,04074819 ! lipoprotein transport GO:0042953 14 8 0,000 0,011608 0,040688 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,011608 0,04062799 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,011608 0,04056815 ! keratinocyte proliferation GO:0043616 15 8 0,000 0,011608 0,04050849 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,011608 0,04044901 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,011608 0,0403897 ! amyloid precursor protein catabolic process GO:0042987 13 8 0,000 0,011608 0,04033057 ! bile acid and bile salt transport GO:0015721 12 8 0,000 0,011608 0,0402716 ! ganglioside metabolic process GO:0001573 16 8 0,000 0,011608 0,04021281 ! regulation of mesenchymal cell proliferation GO:0010464 12 8 0,000 0,011608 0,04015419 ! reflex GO:0060004 16 8 0,000 0,011608 0,04009574 ! positive regulation of isotype switching GO:0045830 16 8 0,000 0,011608 0,04003747 GO:0045911|positive regulation of DNA recombination, ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,011608 0,03997936 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of interleukin-12 biosynthetic process GO:0045075 10 8 0,000 0,011608 0,03992142 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,011608 0,03986364 ! glycerolipid catabolic process GO:0046503 11 8 0,000 0,011608 0,03980604 ! positive regulation of chemokine biosynthetic process GO:0045080 9 8 0,000 0,011608 0,0397486 ! hemoglobin metabolic process GO:0020027 12 8 0,000 0,011608 0,03969132 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,011608 0,03963421 ! nerve growth factor receptor signaling pathway GO:0048011 12 8 0,000 0,011608 0,03957726 ! insulin-like growth factor receptor signaling pathway GO:0048009 16 8 0,000 0,011608 0,03952048 ! adrenal gland development GO:0030325 18 8 0,000 0,011608 0,03946386 ! embryonic cranial skeleton morphogenesis GO:0048701 12 8 0,000 0,011608 0,03940741 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,011608 0,03935111 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,011608 0,03929497 ! proline metabolic process GO:0006560 9 8 0,000 0,011608 0,039239 ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,011608 0,03918318 ! regulation of interleukin-8 biosynthetic process GO:0045414 10 8 0,000 0,011608 0,03912752 ! regulation of pigmentation during development GO:0048070 18 8 0,000 0,011608 0,03907202 ! central nervous system neuron axonogenesis GO:0021955 16 8 0,000 0,011608 0,03901668 GO:0021952|central nervous system projection neuron axonogenesis, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 15 8 0,000 0,011608 0,03896149 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,011608 0,03890646 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,011608 0,03885159 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of activated T cell proliferation GO:0042104 19 8 0,000 0,011608 0,03879687 ! galactose metabolic process GO:0006012 14 8 0,000 0,011608 0,0387423 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,011608 0,03868789 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,011608 0,03863363 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,011608 0,03857952 ! neurotransmitter catabolic process GO:0042135 16 8 0,000 0,011608 0,03852556 ! ruffle organization GO:0031529 12 8 0,000 0,011608 0,03847175 ! osteoblast development GO:0002076 14 8 0,000 0,011608 0,0384181 ! macroautophagy GO:0016236 14 8 0,000 0,011608 0,03836459 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,011608 0,03831123 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,011608 0,03825802 ! regulation of Notch signaling pathway GO:0008593 22 8 0,000 0,011608 0,03820496 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,011608 0,03815204 GO:0030204|chondroitin sulfate metabolic process, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 14 8 0,000 0,011608 0,03809928 ! G1 DNA damage checkpoint GO:0031571 19 8 0,000 0,011608 0,03804665 ! protein retention in ER lumen GO:0006621 16 8 0,000 0,011608 0,03799417 ! cardiac muscle cell differentiation GO:0055007 12 8 0,000 0,011608 0,03794184 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 8 0,000 0,011608 0,03788965 ! regulation of circadian rhythm GO:0042752 13 8 0,000 0,011608 0,0378376 ! pigment granule localization GO:0051875 14 8 0,000 0,011608 0,0377857 ! positive regulation of cytokine production during immune response GO:0002720 12 8 0,000 0,011608 0,03773394 ! antigen processing and presentation of endogenous antigen GO:0019883 14 8 0,000 0,011608 0,03768232 ! response to tropane GO:0014073 14 8 0,000 0,011608 0,03763084 GO:0042220|response to cocaine, ! positive regulation of systemic arterial blood pressure GO:0003084 12 8 0,000 0,011608 0,0375795 ! embryonic axis specification GO:0000578 12 8 0,000 0,011608 0,03752831 ! negative regulation of interferon-gamma production GO:0032689 12 8 0,000 0,011608 0,03747725 ! negative regulation of systemic arterial blood pressure GO:0003085 18 8 0,000 0,011608 0,03742633 ! sphingomyelin metabolic process GO:0006684 11 8 0,000 0,011608 0,03737554 ! snRNA metabolic process GO:0016073 10 8 0,000 0,011608 0,0373249 GO:0016180|snRNA processing, ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 0,011608 0,03727439 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,011608 0,03722402 ! regulation of mitochondrial membrane potential GO:0051881 14 8 0,000 0,011608 0,03717379 ! regulation of interleukin-10 production GO:0032653 12 8 0,000 0,011608 0,03712369 ! positive regulation of monooxygenase activity GO:0032770 12 8 0,000 0,011608 0,03707372 ! protein import into peroxisome matrix GO:0016558 15 8 0,000 0,011608 0,03702389 ! establishment of nucleus localization GO:0040023 14 8 0,000 0,011608 0,0369742 ! icosanoid secretion GO:0032309 12 8 0,000 0,011608 0,03692463 GO:0050482|arachidonic acid secretion, ! intracellular lipid transport GO:0032365 14 8 0,000 0,011608 0,0368752 ! regulation of transcription from RNA polymerase III promoter GO:0006359 11 8 0,000 0,011608 0,0368259 ! negative regulation of oxidoreductase activity GO:0051354 13 8 0,000 0,011608 0,03677674 ! positive regulation of interleukin-1 beta secretion GO:0050718 10 8 0,000 0,011608 0,0367277 ! regulation of T-helper 1 type immune response GO:0002825 10 8 0,000 0,011608 0,0366788 ! S phase GO:0051320 8 8 0,000 0,011608 0,03663002 GO:0000084|S phase of mitotic cell cycle, ! negative regulation of neuroblast proliferation GO:0007406 25 8 0,000 0,011608 0,03658138 ! regulation of macrophage differentiation GO:0045649 15 8 0,000 0,011608 0,03653286 ! negative regulation of osteoclast differentiation GO:0045671 12 8 0,000 0,011608 0,03648447 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,011608 0,03643621 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 8 0,000 0,011608 0,03638808 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,011608 0,03634007 ! melanin biosynthetic process GO:0042438 11 8 0,000 0,011608 0,0362922 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,011608 0,03624444 ! regulation of synaptogenesis GO:0051963 12 8 0,000 0,011608 0,03619682 ! hormone catabolic process GO:0042447 13 8 0,000 0,011608 0,03614931 ! nicotinamide nucleotide biosynthetic process GO:0019359 12 8 0,000 0,011608 0,03610193 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,011608 0,03605468 ! positive regulation of ATPase activity GO:0032781 16 8 0,000 0,011608 0,03600755 ! trophectodermal cell differentiation GO:0001829 10 8 0,000 0,011608 0,03596054 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,011608 0,03591366 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,011608 0,0358669 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,011608 0,03582026 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 0,011608 0,03577374 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,011608 0,03572734 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,011608 0,03568106 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 0,011608 0,0356349 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 8 0,000 0,011608 0,03558886 ! negative regulation of B cell activation GO:0050869 17 8 0,000 0,011608 0,03554294 ! behavioral response to nicotine GO:0035095 13 8 0,000 0,011608 0,03549713 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,011608 0,03545145 GO:0000076|DNA replication checkpoint, ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 0,011608 0,03540588 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 16 8 0,000 0,011608 0,03536043 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 14 8 0,000 0,011608 0,0353151 ! regulation of microtubule polymerization GO:0031113 14 8 0,000 0,011608 0,03526988 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01304982 0,03960002 ! regulation of developmental growth GO:0048638 14 9 0,000 0,01304982 0,03954944 ! negative regulation of smooth muscle cell proliferation GO:0048662 15 9 0,000 0,01304982 0,039499 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01304982 0,03944868 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 9 0,000 0,01304982 0,03939849 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 11 9 0,000 0,01304982 0,03934843 ! negative regulation of lipid biosynthetic process GO:0051055 13 9 0,000 0,01304982 0,03929849 ! glycerol-3-phosphate metabolic process GO:0006072 11 9 0,000 0,01304982 0,03924869 ! regulation of cellular amine metabolic process GO:0033238 12 9 0,000 0,01304982 0,039199 ! cell volume homeostasis GO:0006884 14 9 0,000 0,01304982 0,03914945 ! regulation of epidermal growth factor receptor activity GO:0007176 14 9 0,000 0,01304982 0,03910002 GO:0010469|regulation of receptor activity, ! regulation of smooth muscle cell migration GO:0014910 22 9 0,000 0,01304982 0,03905071 ! UTP metabolic process GO:0046051 10 9 0,000 0,01304982 0,03900153 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! prostaglandin biosynthetic process GO:0001516 15 9 0,000 0,01304982 0,03895247 GO:0046457|prostanoid biosynthetic process, ! succinate metabolic process GO:0006105 16 9 0,000 0,01304982 0,03890353 ! smoothened signaling pathway GO:0007224 10 9 0,000 0,01304982 0,03885472 ! protein complex disassembly GO:0043241 17 9 0,000 0,01304982 0,03880603 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01304982 0,03875746 ! estrogen metabolic process GO:0008210 16 9 0,000 0,01304982 0,03870902 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01304982 0,03866069 ! photoreceptor cell development GO:0042461 17 9 0,000 0,01304982 0,03861249 GO:0046530|photoreceptor cell differentiation, ! cytoplasmic sequestering of transcription factor GO:0042994 12 9 0,000 0,01304982 0,0385644 ! negative regulation of muscle cell differentiation GO:0051148 10 9 0,000 0,01304982 0,03851643 ! microtubule bundle formation GO:0001578 14 9 0,000 0,01304982 0,03846859 ! T-helper 1 type immune response GO:0042088 13 9 0,000 0,01304982 0,03842086 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 22 9 0,000 0,01304982 0,03837325 ! lung alveolus development GO:0048286 18 9 0,000 0,01304982 0,03832576 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01304982 0,03827839 ! pseudouridine synthesis GO:0001522 10 9 0,000 0,01304982 0,03823113 ! endothelial cell differentiation GO:0045446 17 9 0,000 0,01304982 0,03818399 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01304982 0,03813696 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01304982 0,03809005 ! endoderm development GO:0007492 12 9 0,000 0,01304982 0,03804326 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01304982 0,03799658 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01304982 0,03795002 ! myeloid leukocyte mediated immunity GO:0002444 12 9 0,000 0,01304982 0,03790357 ! astrocyte differentiation GO:0048708 17 9 0,000 0,01304982 0,03785723 ! L-phenylalanine metabolic process GO:0006558 11 9 0,000 0,01304982 0,03781101 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 10 9 0,000 0,01304982 0,03776489 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01304982 0,0377189 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 13 9 0,000 0,01304982 0,03767301 ! reverse cholesterol transport GO:0043691 17 9 0,000 0,01304982 0,03762723 ! indolalkylamine metabolic process GO:0006586 15 9 0,000 0,01304982 0,03758157 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! melanin metabolic process GO:0006582 15 9 0,000 0,01304982 0,03753602 ! embryonic eye morphogenesis GO:0048048 15 9 0,000 0,01304982 0,03749057 ! macrophage activation GO:0042116 14 9 0,000 0,01304982 0,03744524 ! multicellular organism growth GO:0035264 16 9 0,000 0,01304982 0,03740002 ! retrograde transport, endosome to Golgi GO:0042147 14 9 0,000 0,01304982 0,0373549 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 0,01304982 0,0373099 ! neuron apoptosis GO:0051402 12 9 0,000 0,01304982 0,037265 ! lens development in camera-type eye GO:0002088 11 9 0,000 0,01304982 0,03722021 ! positive regulation of vasodilation GO:0045909 14 9 0,000 0,01304982 0,03717553 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01304982 0,03713095 ! positive regulation of muscle contraction GO:0045933 13 9 0,000 0,01304982 0,03708648 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01304982 0,03704212 ! regulation of smoothened signaling pathway GO:0008589 15 9 0,000 0,01304982 0,03699787 ! Schwann cell differentiation GO:0014037 20 9 0,000 0,01304982 0,03695372 ! acyl-CoA metabolic process GO:0006637 14 9 0,000 0,01304982 0,03690967 ! regulation of gliogenesis GO:0014013 21 9 0,000 0,01304982 0,03686573 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 21 9 0,000 0,01304982 0,03682189 ! oligodendrocyte development GO:0014003 13 9 0,000 0,01304982 0,03677816 ! alpha-beta T cell differentiation GO:0046632 15 9 0,000 0,01304982 0,03673454 ! segment specification GO:0007379 11 9 0,000 0,01304982 0,03669101 ! cellular extravasation GO:0045123 12 9 0,000 0,01304982 0,03664759 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01304982 0,03660427 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 13 9 0,000 0,01304982 0,03656106 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01304982 0,03651794 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01304982 0,03647493 ! antigen processing and presentation of exogenous antigen GO:0019884 11 9 0,000 0,01304982 0,03643202 ! positive regulation of production of molecular mediator of immune response GO:0002702 13 9 0,000 0,01304982 0,03638921 ! purine nucleoside triphosphate catabolic process GO:0009146 13 9 0,000 0,01304982 0,03634649 ! regulation of T cell differentiation in the thymus GO:0033081 14 9 0,000 0,01304982 0,03630388 ! response to amine stimulus GO:0014075 13 9 0,000 0,01304982 0,03626137 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of protein kinase B signaling cascade GO:0051896 16 9 0,000 0,01304982 0,03621896 ! erythrocyte development GO:0048821 13 9 0,000 0,01304982 0,03617665 ! renal water homeostasis GO:0003091 13 9 0,000 0,01304982 0,03613444 ! positive regulation of tumor necrosis factor production GO:0032760 10 9 0,000 0,01304982 0,03609232 ! nucleosome disassembly GO:0006337 13 9 0,000 0,01304982 0,03605031 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! spinal cord motor neuron differentiation GO:0021522 12 9 0,000 0,01304982 0,03600839 ! transcription from RNA polymerase I promoter GO:0006360 14 9 0,000 0,01304982 0,03596657 ! induction of an organ GO:0001759 13 9 0,000 0,01304982 0,03592484 ! leukocyte activation during immune response GO:0002366 15 9 0,000 0,01304982 0,03588321 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 11 9 0,000 0,01304982 0,03584168 ! cerebellum morphogenesis GO:0021587 13 9 0,000 0,01304982 0,03580025 GO:0021696|cerebellar cortex morphogenesis, ! retinal ganglion cell axon guidance GO:0031290 11 9 0,000 0,01304982 0,03575891 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01304982 0,03571766 ! sterol catabolic process GO:0016127 11 9 0,000 0,01304982 0,03567651 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 18 9 0,000 0,01304982 0,03563546 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01304982 0,0355945 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 14 9 0,000 0,01304982 0,03555363 ! positive regulation of interleukin-1 secretion GO:0050716 11 9 0,000 0,01304982 0,03551286 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 0,01304982 0,03547218 ! negative regulation of cytokine secretion GO:0050710 13 9 0,000 0,01304982 0,03543159 ! prophase GO:0051324 12 9 0,000 0,01304982 0,0353911 ! neuroblast proliferation GO:0007405 19 9 0,000 0,01304982 0,0353507 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 16 9 0,000 0,01304982 0,03531039 ! peptidyl-threonine modification GO:0018210 22 9 0,000 0,01304982 0,03527017 ! regulation of interleukin-1 beta secretion GO:0050706 12 9 0,000 0,01304982 0,03523005 ! ubiquinone metabolic process GO:0006743 11 9 0,000 0,01304982 0,03519002 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of erythrocyte differentiation GO:0045648 20 9 0,000 0,01304982 0,03515007 ! acid secretion GO:0046717 14 9 0,000 0,01304982 0,03511022 ! purine base metabolic process GO:0006144 18 9 0,000 0,01304982 0,03507046 ! detection of calcium ion GO:0005513 13 9 0,000 0,01304982 0,03503078 ! myeloid cell homeostasis GO:0002262 10 9 0,000 0,01304982 0,0349912 ! regulation of fibrinolysis GO:0051917 14 9 0,000 0,01304982 0,03495171 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01304982 0,0349123 ! natural killer cell mediated immunity GO:0002228 14 9 0,000 0,01304982 0,03487299 GO:0042267|natural killer cell mediated cytotoxicity, ! negative regulation of blood vessel endothelial cell migration GO:0043537 18 9 0,000 0,01304982 0,03483376 ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01304982 0,03479462 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01304982 0,03475557 ! defense response to Gram-positive bacterium GO:0050830 11 9 0,000 0,01304982 0,03471661 ! prepulse inhibition GO:0060134 14 9 0,000 0,01304982 0,03467773 ! sequestering of metal ion GO:0051238 12 9 0,000 0,01304982 0,03463894 ! lamellipodium assembly GO:0030032 12 9 0,000 0,01304982 0,03460024 ! regulation of embryonic development GO:0045995 17 9 0,000 0,01304982 0,03456162 ! mitochondrion localization GO:0051646 15 9 0,000 0,01304982 0,03452309 ! localization within membrane GO:0051668 15 9 0,000 0,01304982 0,03448465 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,0144896 0,03824675 ! axon extension GO:0048675 13 10 0,000 0,0144896 0,03820426 ! neuron fate specification GO:0048665 12 10 0,000 0,0144896 0,03816186 ! regulation of epithelial cell differentiation GO:0030856 20 10 0,000 0,0144896 0,03811955 ! cortical actin cytoskeleton organization GO:0030866 24 10 0,000 0,0144896 0,03807733 ! associative learning GO:0008306 19 10 0,000 0,0144896 0,03803521 ! positive regulation of B cell proliferation GO:0030890 14 10 0,000 0,0144896 0,03799318 ! cellular copper ion homeostasis GO:0006878 14 10 0,000 0,0144896 0,03795125 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,0144896 0,03790941 ! CTP metabolic process GO:0046036 11 10 0,000 0,0144896 0,03786766 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 17 10 0,000 0,0144896 0,037826 ! GTP metabolic process GO:0046039 11 10 0,000 0,0144896 0,03778443 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,0144896 0,03774295 GO:0007520|myoblast fusion, ! actin-myosin filament sliding GO:0033275 14 10 0,000 0,0144896 0,03770157 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,0144896 0,03766028 ! social behavior GO:0035176 15 10 0,000 0,0144896 0,03761907 ! sulfate transport GO:0008272 12 10 0,000 0,0144896 0,03757796 ! regulation of activated T cell proliferation GO:0046006 22 10 0,000 0,0144896 0,03753693 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 19 10 0,000 0,0144896 0,037496 ! artery development GO:0060840 20 10 0,000 0,0144896 0,03745515 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 13 10 0,000 0,0144896 0,0374144 ! response to pain GO:0048265 20 10 0,000 0,0144896 0,03737373 ! COPI coating of Golgi vesicle GO:0048205 15 10 0,000 0,0144896 0,03733315 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,0144896 0,03729266 ! phospholipid efflux GO:0033700 17 10 0,000 0,0144896 0,03725226 ! hippocampus development GO:0021766 19 10 0,000 0,0144896 0,03721194 ! positive regulation of transcription factor import into nucleus GO:0042993 21 10 0,000 0,0144896 0,03717171 ! amyloid precursor protein metabolic process GO:0042982 16 10 0,000 0,0144896 0,03713157 ! blood vessel remodeling GO:0001974 23 10 0,000 0,0144896 0,03709151 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,0144896 0,03705154 ! pathogenesis GO:0009405 13 10 0,000 0,0144896 0,03701166 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,0144896 0,03697186 ! two-component signal transduction system (phosphorelay) GO:0000160 15 10 0,000 0,0144896 0,03693215 ! negative regulation of striated muscle development GO:0045843 13 10 0,000 0,0144896 0,03689252 ! protein targeting to ER GO:0045047 21 10 0,000 0,0144896 0,03685298 ! regulation of S phase of mitotic cell cycle GO:0007090 19 10 0,000 0,0144896 0,03681352 ! arginine catabolic process GO:0006527 12 10 0,000 0,0144896 0,03677415 ! melanocyte differentiation GO:0030318 16 10 0,000 0,0144896 0,03673486 GO:0050931|pigment cell differentiation, ! telomere maintenance via telomerase GO:0007004 14 10 0,000 0,0144896 0,03669566 GO:0010833|telomere maintenance via telomere lengthening, ! polyamine metabolic process GO:0006595 14 10 0,000 0,0144896 0,03665654 ! positive regulation of endothelial cell migration GO:0010595 20 10 0,000 0,0144896 0,0366175 ! B cell proliferation GO:0042100 16 10 0,000 0,0144896 0,03657854 ! nucleobase biosynthetic process GO:0046112 20 10 0,000 0,0144896 0,03653967 ! mannose metabolic process GO:0006013 11 10 0,000 0,0144896 0,03650088 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,0144896 0,03646218 ! forebrain cell migration GO:0021885 17 10 0,000 0,0144896 0,03642355 ! lipid digestion GO:0044241 15 10 0,000 0,0144896 0,03638501 ! substrate-bound cell migration GO:0006929 11 10 0,000 0,0144896 0,03634655 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,0144896 0,03630816 ! receptor clustering GO:0043113 18 10 0,000 0,0144896 0,03626986 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,0144896 0,03623165 ! UV protection GO:0009650 14 10 0,000 0,0144896 0,03619351 ! entry into host cell GO:0030260 21 10 0,000 0,0144896 0,03615545 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of lipoprotein lipase activity GO:0051004 20 10 0,000 0,0144896 0,03611747 ! behavioral fear response GO:0001662 19 10 0,000 0,0144896 0,03607957 GO:0002209|behavioral defense response, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,0144896 0,03604175 ! negative regulation of ossification GO:0030279 21 10 0,000 0,0144896 0,03600401 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 23 10 0,000 0,0144896 0,03596635 ! protein homotetramerization GO:0051289 20 10 0,000 0,0144896 0,03592877 ! positive regulation of peptide secretion GO:0002793 16 10 0,000 0,0144896 0,03589126 ! response to dsRNA GO:0043331 19 10 0,000 0,0144896 0,03585384 ! DNA ligation GO:0006266 16 10 0,000 0,0144896 0,03581649 ! phosphoinositide 3-kinase cascade GO:0014065 26 10 0,000 0,0144896 0,03577922 ! regulation of interleukin-4 production GO:0032673 18 10 0,000 0,0144896 0,03574203 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,0144896 0,03570491 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,0144896 0,03566788 ! postreplication repair GO:0006301 16 10 0,000 0,0144896 0,03563091 ! fucose catabolic process GO:0019317 17 10 0,000 0,0144896 0,03559403 GO:0042355|L-fucose catabolic process, ! mRNA cleavage GO:0006379 14 10 0,000 0,0144896 0,03555722 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,0144896 0,03552049 ! hindbrain morphogenesis GO:0021575 16 10 0,000 0,0144896 0,03548383 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 10 0,000 0,0144896 0,03544725 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 13 10 0,000 0,0144896 0,03541074 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,0144896 0,03537431 ! positive regulation of neuron differentiation GO:0045666 13 10 0,000 0,0144896 0,03533796 ! positive regulation of leukocyte migration GO:0002687 24 10 0,000 0,0144896 0,03530168 ! multicellular organismal water homeostasis GO:0050891 14 10 0,000 0,0144896 0,03526547 ! negative regulation of lymphocyte differentiation GO:0045620 13 10 0,000 0,0144896 0,03522934 ! methionine biosynthetic process GO:0009086 13 10 0,000 0,0144896 0,03519328 ! oocyte differentiation GO:0009994 14 10 0,000 0,0144896 0,03515729 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 14 10 0,000 0,0144896 0,03512138 ! spleen development GO:0048536 17 10 0,000 0,0144896 0,03508554 ! negative regulation of BMP signaling pathway GO:0030514 15 10 0,000 0,0144896 0,03504978 ! regulation of RNA splicing GO:0043484 15 10 0,000 0,0144896 0,03501409 ! positive regulation of viral reproduction GO:0048524 14 10 0,000 0,0144896 0,03497847 ! blastocyst formation GO:0001825 14 10 0,000 0,0144896 0,03494292 ! embryonic gut development GO:0048566 13 10 0,000 0,0144896 0,03490744 ! quinone cofactor metabolic process GO:0042375 12 10 0,000 0,0144896 0,03487204 ! cerebellar cortex development GO:0021695 14 10 0,000 0,0144896 0,03483671 ! activation of innate immune response GO:0002218 10 10 0,000 0,0144896 0,03480145 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,0144896 0,03476626 ! insulin secretion GO:0030073 18 10 0,000 0,0144896 0,03473114 ! cytoplasmic sequestering of protein GO:0051220 15 10 0,000 0,0144896 0,0346961 ! response to nicotine GO:0035094 18 10 0,000 0,0144896 0,03466112 ! establishment of cell polarity GO:0030010 12 10 0,000 0,0144896 0,03462622 ! nucleus localization GO:0051647 16 10 0,000 0,0144896 0,03459138 ! regulation of synapse organization GO:0050807 14 10 0,000 0,0144896 0,03455661 ! negative regulation of muscle development GO:0048635 14 11 0,000 0,01592737 0,03794743 ! positive regulation of glucose metabolic process GO:0010907 17 11 0,000 0,01592737 0,03790937 ! ER-associated protein catabolic process GO:0030433 17 11 0,000 0,01592737 0,03787138 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of blood pressure GO:0045776 25 11 0,000 0,01592737 0,03783347 ! cortical cytoskeleton organization GO:0030865 25 11 0,000 0,01592737 0,03779564 ! virus-host interaction GO:0019048 20 11 0,000 0,01592737 0,03775788 ! thyroid gland development GO:0030878 20 11 0,000 0,01592737 0,0377202 ! pentose-phosphate shunt GO:0006098 14 11 0,000 0,01592737 0,03768259 GO:0006740|NADPH regeneration, ! non-recombinational repair GO:0000726 19 11 0,000 0,01592737 0,03764506 GO:0006303|double-strand break repair via nonhomologous end joining, ! synapsis GO:0007129 15 11 0,000 0,01592737 0,0376076 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 11 11 0,000 0,01592737 0,03757022 ! Golgi vesicle budding GO:0048194 18 11 0,000 0,01592737 0,03753291 ! elastic fiber assembly GO:0048251 17 11 0,000 0,01592737 0,03749567 ! regulation of positive chemotaxis GO:0050926 19 11 0,000 0,01592737 0,03745851 GO:0050927|positive regulation of positive chemotaxis, ! regulation of glycolysis GO:0006110 18 11 0,000 0,01592737 0,03742142 ! dopamine receptor signaling pathway GO:0007212 25 11 0,000 0,01592737 0,03738441 ! regulation of cell projection assembly GO:0060491 22 11 0,000 0,01592737 0,03734747 ! positive regulation of lipid metabolic process GO:0045834 15 11 0,000 0,01592737 0,0373106 ! bone resorption GO:0045453 16 11 0,000 0,01592737 0,0372738 ! regulation of chemokine biosynthetic process GO:0045073 13 11 0,000 0,01592737 0,03723708 ! peptide or protein amino-terminal blocking GO:0018409 16 11 0,000 0,01592737 0,03720043 ! ventral spinal cord development GO:0021517 15 11 0,000 0,01592737 0,03716385 ! regulated secretory pathway GO:0045055 15 11 0,000 0,01592737 0,03712734 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 19 11 0,000 0,01592737 0,03709091 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! regulation of catecholamine secretion GO:0050433 21 11 0,000 0,01592737 0,03705455 ! syncytium formation GO:0006949 15 11 0,000 0,01592737 0,03701825 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01592737 0,03698203 ! glucan biosynthetic process GO:0009250 14 11 0,000 0,01592737 0,03694588 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 16 11 0,000 0,01592737 0,0369098 ! Golgi organization GO:0007030 19 11 0,000 0,01592737 0,03687379 ! response to X-ray GO:0010165 19 11 0,000 0,01592737 0,03683785 ! retinoic acid receptor signaling pathway GO:0048384 16 11 0,000 0,01592737 0,03680198 ! adult heart development GO:0007512 12 11 0,000 0,01592737 0,03676618 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01592737 0,03673045 ! epithelial cell development GO:0002064 16 11 0,000 0,01592737 0,03669479 ! actin cytoskeleton reorganization GO:0031532 20 11 0,000 0,01592737 0,0366592 ! temperature homeostasis GO:0001659 16 11 0,000 0,01592737 0,03662368 ! positive regulation vascular endothelial growth factor production GO:0010575 19 11 0,000 0,01592737 0,03658823 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01592737 0,03655284 ! motor axon guidance GO:0008045 17 11 0,000 0,01592737 0,03651752 ! copper ion homeostasis GO:0055070 15 11 0,000 0,01592737 0,03648228 ! protein targeting to peroxisome GO:0006625 21 11 0,000 0,01592737 0,03644709 ! regulation of bone resorption GO:0045124 27 11 0,000 0,01592737 0,03641198 ! stem cell development GO:0048864 30 11 0,000 0,01592737 0,03637694 GO:0019827|stem cell maintenance, ! alpha-beta T cell activation GO:0046631 18 11 0,000 0,01592737 0,03634196 ! negative regulation of axonogenesis GO:0050771 26 11 0,000 0,01592737 0,03630705 ! regulation of phagocytosis GO:0050764 16 11 0,000 0,01592737 0,0362722 ! regulation of insulin receptor signaling pathway GO:0046626 17 11 0,000 0,01592737 0,03623743 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01592737 0,03620272 ! nucleoside triphosphate catabolic process GO:0009143 16 11 0,000 0,01592737 0,03616807 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01592737 0,0361335 ! synaptic vesicle exocytosis GO:0016079 16 11 0,000 0,01592737 0,03609898 ! regulation of B cell differentiation GO:0045577 23 11 0,000 0,01592737 0,03606454 ! cranial nerve development GO:0021545 14 11 0,000 0,01592737 0,03603016 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01592737 0,03599584 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01592737 0,0359616 ! salivary gland development GO:0007431 24 11 0,000 0,01592737 0,03592741 ! negative regulation of neurological system process GO:0031645 20 11 0,000 0,01592737 0,03589329 ! regulation of leukocyte migration GO:0002685 25 11 0,000 0,01592737 0,03585924 ! musculoskeletal movement GO:0050881 16 11 0,000 0,01592737 0,03582525 GO:0050879|multicellular organismal movement, ! nitric oxide mediated signal transduction GO:0007263 20 11 0,000 0,01592737 0,03579132 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01592737 0,03575746 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01592737 0,03572366 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 19 11 0,000 0,01592737 0,03568993 ! cholesterol efflux GO:0033344 20 11 0,000 0,01592737 0,03565626 ! digestive tract morphogenesis GO:0048546 16 11 0,000 0,01592737 0,03562266 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 11 0,000 0,01592737 0,03558911 ! thyroid hormone metabolic process GO:0042403 17 11 0,000 0,01592737 0,03555563 ! leukocyte mediated cytotoxicity GO:0001909 18 11 0,000 0,01592737 0,03552222 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01592737 0,03548886 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 21 11 0,000 0,01592737 0,03545557 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01592737 0,03542234 ! cardiac cell differentiation GO:0035051 18 11 0,000 0,01592737 0,03538917 ! defense response to fungus GO:0050832 13 11 0,000 0,01592737 0,03535607 ! lysogeny GO:0030069 20 11 0,000 0,01592737 0,03532303 GO:0019047|provirus integration, ! T cell receptor signaling pathway GO:0050852 22 11 0,000 0,01592737 0,03529004 ! acrosome reaction GO:0007340 14 11 0,000 0,01592737 0,03525712 ! regulation of synapse structure and activity GO:0050803 15 11 0,000 0,01592737 0,03522427 ! regulation of steroid biosynthetic process GO:0050810 13 11 0,000 0,01592737 0,03519147 ! rRNA transcription GO:0009303 19 12 0,000 0,0173631 0,03832803 ! reproductive cellular process GO:0048610 15 12 0,000 0,0173631 0,03829241 ! regulation of membrane protein ectodomain proteolysis GO:0051043 17 12 0,000 0,0173631 0,03825686 ! pteridine and derivative biosynthetic process GO:0042559 15 12 0,000 0,0173631 0,03822137 ! dicarboxylic acid transport GO:0006835 21 12 0,000 0,0173631 0,03818595 ! phosphate transport GO:0006817 15 12 0,000 0,0173631 0,03815059 ! peroxisomal transport GO:0043574 22 12 0,000 0,0173631 0,0381153 ! mating GO:0007618 16 12 0,000 0,0173631 0,03808007 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,0173631 0,03804491 ! heart looping GO:0001947 15 12 0,000 0,0173631 0,03800981 ! negative regulation of cell-matrix adhesion GO:0001953 31 12 0,000 0,0173631 0,03797478 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 20 12 0,000 0,0173631 0,03793981 ! negative regulation of proteolysis GO:0045861 17 12 0,000 0,0173631 0,03790491 ! T cell selection GO:0045058 25 12 0,000 0,0173631 0,03787007 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,0173631 0,0378353 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 17 12 0,000 0,0173631 0,03780058 ! oligodendrocyte differentiation GO:0048709 19 12 0,000 0,0173631 0,03776594 ! plasma membrane organization GO:0007009 19 12 0,000 0,0173631 0,03773135 ! focal adhesion formation GO:0048041 28 12 0,000 0,0173631 0,03769683 ! mitotic spindle organization GO:0007052 16 12 0,000 0,0173631 0,03766237 ! cellular carbohydrate catabolic process GO:0044275 14 12 0,000 0,0173631 0,03762798 ! regulation of intracellular pH GO:0051453 19 12 0,000 0,0173631 0,03759365 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,0173631 0,03755938 ! monoamine transport GO:0015844 14 12 0,000 0,0173631 0,03752517 ! regulation of vascular endothelial growth factor production GO:0010574 20 12 0,000 0,0173631 0,03749103 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 18 12 0,000 0,0173631 0,03745694 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,0173631 0,03742292 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,0173631 0,03738896 ! regulation of organ growth GO:0046620 14 12 0,000 0,0173631 0,03735506 ! vasoconstriction GO:0042310 18 12 0,000 0,0173631 0,03732123 ! RNA-dependent DNA replication GO:0006278 16 12 0,000 0,0173631 0,03728745 ! regulation of interleukin-8 production GO:0032677 19 12 0,000 0,0173631 0,03725374 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,0173631 0,03722009 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,0173631 0,0371865 ! histone deacetylation GO:0016575 14 12 0,000 0,0173631 0,03715296 ! histone acetylation GO:0016573 27 12 0,000 0,0173631 0,03711949 ! DNA methylation GO:0006306 19 12 0,000 0,0173631 0,03708608 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 19 12 0,000 0,0173631 0,03705273 ! protein sumoylation GO:0016925 14 12 0,000 0,0173631 0,03701944 ! chromatin silencing GO:0006342 23 12 0,000 0,0173631 0,03698621 ! negative regulation of MAPKKK cascade GO:0043409 23 12 0,000 0,0173631 0,03695304 ! gland morphogenesis GO:0022612 24 12 0,000 0,0173631 0,03691993 ! regulation of hormone metabolic process GO:0032350 21 12 0,000 0,0173631 0,03688687 ! zymogen activation GO:0031638 16 12 0,000 0,0173631 0,03685388 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,0173631 0,03682094 ! nucleosome positioning GO:0016584 13 12 0,000 0,0173631 0,03678807 ! T cell homeostasis GO:0043029 22 12 0,000 0,0173631 0,03675525 ! regulation of isotype switching GO:0045191 22 12 0,000 0,0173631 0,03672249 ! glutathione biosynthetic process GO:0006750 14 12 0,000 0,0173631 0,03668979 ! response to gamma radiation GO:0010332 21 12 0,000 0,0173631 0,03665715 ! regulation of osteoclast differentiation GO:0045670 18 12 0,000 0,0173631 0,03662457 ! regulation of T-helper 2 cell differentiation GO:0045628 19 12 0,000 0,0173631 0,03659204 ! aromatic amino acid family catabolic process GO:0009074 16 12 0,000 0,0173631 0,03655957 ! serine family amino acid biosynthetic process GO:0009070 16 12 0,000 0,0173631 0,03652716 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,0173631 0,03649481 ! male genitalia development GO:0030539 15 12 0,000 0,0173631 0,03646251 ! regulation of cellular carbohydrate catabolic process GO:0043471 19 12 0,000 0,0173631 0,03643027 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of fatty acid oxidation GO:0046320 20 12 0,000 0,0173631 0,03639809 ! establishment or maintenance of apical/basal cell polarity GO:0035088 23 12 0,000 0,0173631 0,03636596 ! developmental induction GO:0031128 16 12 0,000 0,0173631 0,03633389 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 15 12 0,000 0,0173631 0,03630188 ! response to cold GO:0009409 15 12 0,000 0,0173631 0,03626993 ! negative regulation of immune effector process GO:0002698 20 12 0,000 0,0173631 0,03623803 ! respiratory burst GO:0045730 22 13 0,000 0,01879681 0,03919581 ! lactation GO:0007595 22 13 0,000 0,01879681 0,0391614 ! tRNA modification GO:0006400 15 13 0,000 0,01879681 0,03912705 ! negative regulation of cell projection organization GO:0031345 29 13 0,000 0,01879681 0,03909276 ! positive regulation of blood pressure GO:0045777 19 13 0,000 0,01879681 0,03905853 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01879681 0,03902435 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 20 13 0,000 0,01879681 0,03899024 ! water transport GO:0006833 21 13 0,000 0,01879681 0,03895619 GO:0042044|fluid transport, ! regulation of B cell proliferation GO:0030888 24 13 0,000 0,01879681 0,0389222 ! regulation of nitric-oxide synthase activity GO:0050999 23 13 0,000 0,01879681 0,03888826 ! copper ion transport GO:0006825 15 13 0,000 0,01879681 0,03885439 ! filopodium assembly GO:0046847 21 13 0,000 0,01879681 0,03882057 ! lipid localization GO:0010876 25 13 0,000 0,01879681 0,03878681 GO:0019915|lipid storage, ! detection of mechanical stimulus GO:0050982 17 13 0,000 0,01879681 0,03875312 ! negative regulation of transcription factor import into nucleus GO:0042992 26 13 0,000 0,01879681 0,03871948 ! cytokine biosynthetic process GO:0042089 17 13 0,000 0,01879681 0,03868589 ! T cell proliferation GO:0042098 24 13 0,000 0,01879681 0,03865237 ! organelle fusion GO:0048284 29 13 0,000 0,01879681 0,03861891 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01879681 0,0385855 ! endocrine pancreas development GO:0031018 19 13 0,000 0,01879681 0,03855215 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 24 13 0,000 0,01879681 0,03851886 ! platelet-derived growth factor receptor signaling pathway GO:0048008 20 13 0,000 0,01879681 0,03848562 ! photoreceptor cell maintenance GO:0045494 20 13 0,000 0,01879681 0,03845245 ! regulation of mRNA processing GO:0050684 21 13 0,000 0,01879681 0,03841933 ! regulation of skeletal muscle fiber development GO:0048742 22 13 0,000 0,01879681 0,03838626 ! methionine metabolic process GO:0006555 16 13 0,000 0,01879681 0,03835326 ! deoxyribonucleotide catabolic process GO:0009264 17 13 0,000 0,01879681 0,03832031 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01879681 0,03828741 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 21 13 0,000 0,01879681 0,03825458 ! negative regulation of endothelial cell migration GO:0010596 22 13 0,000 0,01879681 0,0382218 ! membrane protein proteolysis GO:0033619 21 13 0,000 0,01879681 0,03818907 GO:0006509|membrane protein ectodomain proteolysis, ! fear response GO:0042596 22 13 0,000 0,01879681 0,0381564 ! neutral amino acid transport GO:0015804 20 13 0,000 0,01879681 0,03812379 ! negative regulation of mitotic cell cycle GO:0045930 32 13 0,000 0,01879681 0,03809124 ! regulation of natural killer cell mediated immunity GO:0002715 21 13 0,000 0,01879681 0,03805873 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 16 13 0,000 0,01879681 0,03802629 ! positive regulation of protein import into nucleus GO:0042307 24 13 0,000 0,01879681 0,0379939 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01879681 0,03796156 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01879681 0,03792928 ! cellular pigmentation GO:0033059 24 13 0,000 0,01879681 0,03789706 ! histone methylation GO:0016571 16 13 0,000 0,01879681 0,03786489 ! regulation of epidermis development GO:0045682 21 13 0,000 0,01879681 0,03783277 ! oxygen transport GO:0015671 20 13 0,000 0,01879681 0,03780071 ! regulation of axon extension GO:0030516 26 13 0,000 0,01879681 0,0377687 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 24 13 0,000 0,01879681 0,03773675 ! detection of bacterium GO:0016045 13 13 0,000 0,01879681 0,03770485 ! L-fucose metabolic process GO:0042354 21 13 0,000 0,01879681 0,037673 ! regulation of NF-kappaB import into nucleus GO:0042345 24 13 0,000 0,01879681 0,03764121 ! positive regulation of homeostatic process GO:0032846 19 13 0,000 0,01879681 0,03760947 ! positive regulation of protein polymerization GO:0032273 21 13 0,000 0,01879681 0,03757779 ! actin filament polymerization GO:0030041 18 13 0,000 0,01879681 0,03754616 ! N-terminal protein amino acid modification GO:0031365 20 14 0,000 0,02022851 0,04037195 ! positive regulation of cellular catabolic process GO:0031331 24 14 0,000 0,02022851 0,04033802 ! G1 phase of mitotic cell cycle GO:0000080 24 14 0,000 0,02022851 0,04030415 ! neuron maturation GO:0042551 24 14 0,000 0,02022851 0,04027034 ! regulation of S phase GO:0033261 25 14 0,000 0,02022851 0,04023658 ! regulation of chemokine production GO:0032642 18 14 0,000 0,02022851 0,04020288 ! myotube differentiation GO:0014902 21 14 0,000 0,02022851 0,04016924 ! double-strand break repair via homologous recombination GO:0000724 24 14 0,000 0,02022851 0,04013565 GO:0000725|recombinational repair, ! negative regulation of bone remodeling GO:0046851 28 14 0,000 0,02022851 0,04010212 ! phospholipid catabolic process GO:0009395 19 14 0,000 0,02022851 0,04006865 ! aminoglycan catabolic process GO:0006026 19 14 0,000 0,02022851 0,04003523 ! vesicle targeting, to, from or within Golgi GO:0048199 19 14 0,000 0,02022851 0,04000187 ! cardiac muscle contraction GO:0060048 28 14 0,000 0,02022851 0,03996856 ! RNA polyadenylation GO:0043631 21 14 0,000 0,02022851 0,03993531 ! cartilage condensation GO:0001502 22 14 0,000 0,02022851 0,03990211 ! gene silencing by RNA GO:0031047 22 14 0,000 0,02022851 0,03986897 ! response to cAMP GO:0051591 20 14 0,000 0,02022851 0,03983589 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 17 14 0,000 0,02022851 0,03980285 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 14 0,000 0,02022851 0,03976988 ! negative regulation of cytokine biosynthetic process GO:0042036 19 14 0,000 0,02022851 0,03973696 ! limbic system development GO:0021761 25 14 0,000 0,02022851 0,03970409 ! positive regulation of ion transport GO:0043270 18 14 0,000 0,02022851 0,03967128 GO:0051928|positive regulation of calcium ion transport, ! startle response GO:0001964 21 14 0,000 0,02022851 0,03963852 ! palate development GO:0060021 19 14 0,000 0,02022851 0,03960581 ! negative regulation of gene expression, epigenetic GO:0045814 30 14 0,000 0,02022851 0,03957316 ! negative regulation of protein amino acid phosphorylation GO:0001933 31 14 0,000 0,02022851 0,03954056 ! regulation of defense response to virus GO:0050688 26 14 0,000 0,02022851 0,03950802 ! response to hexose stimulus GO:0009746 22 14 0,000 0,02022851 0,03947553 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! epidermis morphogenesis GO:0048730 31 14 0,000 0,02022851 0,03944309 ! arginine metabolic process GO:0006525 17 14 0,000 0,02022851 0,03941071 ! glutamate metabolic process GO:0006536 21 14 0,000 0,02022851 0,03937838 ! glycine metabolic process GO:0006544 22 14 0,000 0,02022851 0,0393461 ! pituitary gland development GO:0021983 24 14 0,000 0,02022851 0,03931388 ! tyrosine metabolic process GO:0006570 20 14 0,000 0,02022851 0,0392817 ! negative regulation of microtubule depolymerization GO:0007026 34 14 0,000 0,02022851 0,03924959 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 21 14 0,000 0,02022851 0,03921752 ! cytokine metabolic process GO:0042107 18 14 0,000 0,02022851 0,0391855 ! NAD metabolic process GO:0019674 25 14 0,000 0,02022851 0,03915354 ! regulation of ion transmembrane transporter activity GO:0032412 19 14 0,000 0,02022851 0,03912163 ! regulation of heart rate GO:0002027 26 14 0,000 0,02022851 0,03908977 ! exocrine system development GO:0035272 29 14 0,000 0,02022851 0,03905797 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,02022851 0,03902621 ! positive regulation of carbohydrate metabolic process GO:0045913 22 14 0,000 0,02022851 0,03899451 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! purine nucleoside monophosphate metabolic process GO:0009126 22 14 0,000 0,02022851 0,03896286 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 25 14 0,000 0,02022851 0,03893126 ! axon cargo transport GO:0008088 29 14 0,000 0,02022851 0,03889971 ! positive regulation of T cell mediated immunity GO:0002711 30 14 0,000 0,02022851 0,03886821 ! negative regulation of protein import into nucleus GO:0042308 27 14 0,000 0,02022851 0,03883677 ! genitalia development GO:0048806 18 14 0,000 0,02022851 0,03880537 ! regulation of interleukin-12 production GO:0032655 20 14 0,000 0,02022851 0,03877403 ! autonomic nervous system development GO:0048483 26 14 0,000 0,02022851 0,03874273 ! tissue regeneration GO:0042246 24 14 0,000 0,02022851 0,03871149 ! negative regulation of protein secretion GO:0050709 22 14 0,000 0,02022851 0,03868029 ! water homeostasis GO:0030104 23 14 0,000 0,02022851 0,03864915 ! cofactor transport GO:0051181 22 14 0,000 0,02022851 0,03861806 ! regulation of acute inflammatory response GO:0002673 21 14 0,000 0,02022851 0,03858701 ! positive regulation of T-helper cell differentiation GO:0045624 20 14 0,000 0,02022851 0,03855602 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,02022851 0,03852507 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,02022851 0,03849418 ! regulation of mRNA stability GO:0043488 30 14 0,000 0,02022851 0,03846334 ! cell killing GO:0001906 22 14 0,000 0,02022851 0,03843254 ! positive regulation of JNK cascade GO:0046330 22 14 0,000 0,02022851 0,03840179 ! epithelial to mesenchymal transition GO:0001837 24 14 0,000 0,02022851 0,0383711 ! negative regulation of mast cell proliferation GO:0070667 26 14 0,000 0,02022851 0,03834045 GO:0042130|negative regulation of T cell proliferation, ! mRNA 3'-end processing GO:0031124 21 14 0,000 0,02022851 0,03830985 ! microspike assembly GO:0030035 25 14 0,000 0,02022851 0,0382793 ! positive regulation of calcium-mediated signaling GO:0050850 27 14 0,000 0,02022851 0,0382488 ! regulation of skeletal muscle tissue development GO:0048641 24 15 0,000 0,02165818 0,04091948 ! superoxide anion generation GO:0042554 19 15 0,000 0,02165818 0,04088692 ! negative regulation of hormone secretion GO:0046888 22 15 0,000 0,02165818 0,04085442 ! skin development GO:0043588 28 15 0,000 0,02165818 0,04082197 ! embryonic hindlimb morphogenesis GO:0035116 28 15 0,000 0,02165818 0,04078957 ! embryonic forelimb morphogenesis GO:0035115 18 15 0,000 0,02165818 0,04075723 ! inositol metabolic process GO:0006020 21 15 0,000 0,02165818 0,04072493 ! retina development in camera-type eye GO:0060041 22 15 0,000 0,02165818 0,04069269 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 22 15 0,000 0,02165818 0,04066049 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 25 15 0,000 0,02165818 0,04062835 ! regulation of transmembrane transporter activity GO:0022898 20 15 0,000 0,02165818 0,04059626 GO:0032409|regulation of transporter activity, ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02165818 0,04056422 ! activation of MAPKK activity GO:0000186 22 15 0,000 0,02165818 0,04053223 ! induction of apoptosis via death domain receptors GO:0008625 19 15 0,000 0,02165818 0,04050029 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 18 15 0,000 0,02165818 0,0404684 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02165818 0,04043656 ! response to osmotic stress GO:0006970 23 15 0,000 0,02165818 0,04040477 ! vesicle coating GO:0006901 26 15 0,000 0,02165818 0,04037303 ! regulation of the force of heart contraction GO:0002026 24 15 0,000 0,02165818 0,04034134 ! preassembly of GPI anchor in ER membrane GO:0016254 22 15 0,000 0,02165818 0,0403097 ! positive regulation of activation of JAK2 kinase activity GO:0010535 15 15 0,000 0,02165818 0,04027811 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 23 15 0,000 0,02165818 0,04024656 ! bone mineralization GO:0030282 17 15 0,000 0,02165818 0,04021507 ! G1/S transition checkpoint GO:0031575 36 15 0,000 0,02165818 0,04018363 ! intermediate filament cytoskeleton organization GO:0045104 27 15 0,000 0,02165818 0,04015224 ! positive regulation of axonogenesis GO:0050772 21 15 0,000 0,02165818 0,04012089 ! regulation of cytokine production during immune response GO:0002718 23 15 0,000 0,02165818 0,0400896 ! T cell differentiation in the thymus GO:0033077 30 15 0,000 0,02165818 0,04005835 ! regulation of cellular pH GO:0030641 23 15 0,000 0,02165818 0,04002715 ! ribosome assembly GO:0042255 17 15 0,000 0,02165818 0,039996 ! cerebellum development GO:0021549 19 15 0,000 0,02165818 0,0399649 ! regulation of monooxygenase activity GO:0032768 29 15 0,000 0,02165818 0,03993385 ! mRNA splice site selection GO:0006376 33 15 0,000 0,02165818 0,03990284 ! positive regulation of cytokine secretion GO:0050715 19 15 0,000 0,02165818 0,03987189 ! regulation of T-helper 2 type immune response GO:0002828 24 15 0,000 0,02165818 0,03984098 ! negative regulation of inflammatory response GO:0050728 18 15 0,000 0,02165818 0,03981012 ! sphingolipid catabolic process GO:0030149 27 15 0,000 0,02165818 0,03977931 GO:0046466|membrane lipid catabolic process, ! positive regulation of bone mineralization GO:0030501 22 15 0,000 0,02165818 0,03974854 ! regulation of erythrocyte differentiation GO:0045646 29 15 0,000 0,02165818 0,03971782 ! muscle maintenance GO:0046716 21 15 0,000 0,02165818 0,03968715 ! C21-steroid hormone biosynthetic process GO:0006700 17 15 0,000 0,02165818 0,03965653 ! activation of NF-kappaB-inducing kinase activity GO:0007250 23 15 0,000 0,02165818 0,03962595 ! intestinal absorption GO:0050892 22 15 0,000 0,02165818 0,03959543 ! regulation of ATPase activity GO:0043462 24 15 0,000 0,02165818 0,03956494 ! dopamine metabolic process GO:0042417 32 15 0,000 0,02165818 0,03953451 ! gas transport GO:0015669 23 15 0,000 0,02165818 0,03950412 ! regulation of RNA stability GO:0043487 31 15 0,000 0,02165818 0,03947378 ! organic cation transport GO:0015695 19 15 0,000 0,02165818 0,03944349 ! heme biosynthetic process GO:0006783 22 15 0,000 0,02165818 0,03941324 ! regulation of BMP signaling pathway GO:0030510 24 15 0,000 0,02165818 0,03938304 ! lymphocyte homeostasis GO:0002260 29 15 0,000 0,02165818 0,03935288 ! aromatic compound biosynthetic process GO:0019438 18 15 0,000 0,02165818 0,03932277 ! release of cytochrome c from mitochondria GO:0001836 29 15 0,000 0,02165818 0,03929271 ! cilium assembly GO:0042384 22 15 0,000 0,02165818 0,03926269 ! regulation of calcium-mediated signaling GO:0050848 28 15 0,000 0,02165818 0,03923272 ! inner ear receptor cell differentiation GO:0060113 30 15 0,000 0,02165818 0,03920279 ! peptide hormone processing GO:0016486 23 15 0,000 0,02165818 0,03917291 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 36 15 0,000 0,02165818 0,03914308 ! sulfur amino acid biosynthetic process GO:0000097 21 16 0,000 0,02308584 0,04169156 ! bone remodeling GO:0046849 24 16 0,000 0,02308584 0,04165985 ! negative regulation of nucleocytoplasmic transport GO:0046823 29 16 0,000 0,02308584 0,04162819 ! positive regulation of nucleocytoplasmic transport GO:0046824 28 16 0,000 0,02308584 0,04159659 ! regulation of cell-cell adhesion GO:0022407 38 16 0,000 0,02308584 0,04156503 ! bile acid metabolic process GO:0008206 23 16 0,000 0,02308584 0,04153351 ! axis specification GO:0009798 26 16 0,000 0,02308584 0,04150205 ! negative regulation of endothelial cell proliferation GO:0001937 33 16 0,000 0,02308584 0,04147063 ! mitotic chromosome condensation GO:0007076 26 16 0,000 0,02308584 0,04143926 ! positive regulation of cell growth GO:0030307 22 16 0,000 0,02308584 0,04140794 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02308584 0,04137666 ! centrosome cycle GO:0007098 18 16 0,000 0,02308584 0,04134544 ! cell differentiation in spinal cord GO:0021515 24 16 0,000 0,02308584 0,04131426 ! regulation of survival gene product expression GO:0045884 23 16 0,000 0,02308584 0,04128312 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 16 0,000 0,02308584 0,04125204 ! cellular response to starvation GO:0009267 26 16 0,000 0,02308584 0,041221 ! DNA integration GO:0015074 25 16 0,000 0,02308584 0,04119 ! branching involved in ureteric bud morphogenesis GO:0001658 24 16 0,000 0,02308584 0,04115906 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 35 16 0,000 0,02308584 0,04112816 ! regulation of exocytosis GO:0017157 28 16 0,000 0,02308584 0,0410973 ! embryonic digit morphogenesis GO:0042733 20 16 0,000 0,02308584 0,04106649 ! positive regulation of biomineral formation GO:0070169 23 16 0,000 0,02308584 0,04103573 ! regulation of vasodilation GO:0042312 26 16 0,000 0,02308584 0,04100502 ! DNA replication initiation GO:0006270 26 16 0,000 0,02308584 0,04097435 ! DNA unwinding during replication GO:0006268 24 16 0,000 0,02308584 0,04094372 ! regulation of steroid metabolic process GO:0019218 23 16 0,000 0,02308584 0,04091315 ! neuron recognition GO:0008038 27 16 0,000 0,02308584 0,04088261 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 22 16 0,000 0,02308584 0,04085213 ! G1 phase GO:0051318 28 16 0,000 0,02308584 0,04082169 ! cellular amino acid derivative catabolic process GO:0042219 31 16 0,000 0,02308584 0,04079129 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02308584 0,04076094 GO:0006626|protein targeting to mitochondrion, ! positive regulation of oxidoreductase activity GO:0051353 22 16 0,000 0,02308584 0,04073063 ! negative regulation of blood coagulation GO:0030195 21 16 0,000 0,02308584 0,04070037 ! negative regulation of tissue remodeling GO:0034104 35 16 0,000 0,02308584 0,04067016 ! NADP metabolic process GO:0006739 22 16 0,000 0,02308584 0,04063999 ! neuromuscular synaptic transmission GO:0007274 31 16 0,000 0,02308584 0,04060986 ! synaptic transmission, cholinergic GO:0007271 24 16 0,000 0,02308584 0,04057978 ! folic acid and derivative metabolic process GO:0006760 18 16 0,000 0,02308584 0,04054974 ! regulation of T-helper cell differentiation GO:0045622 25 16 0,000 0,02308584 0,04051975 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02308584 0,0404898 ! aspartate family amino acid biosynthetic process GO:0009067 19 16 0,000 0,02308584 0,0404599 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 24 16 0,000 0,02308584 0,04043004 ! regulation of blood vessel endothelial cell migration GO:0043535 37 16 0,000 0,02308584 0,04040022 ! RNA 3'-end processing GO:0031123 23 16 0,000 0,02308584 0,04037045 ! defense response to virus GO:0051607 28 16 0,000 0,02308584 0,04034072 ! peptide hormone secretion GO:0030072 26 16 0,000 0,02308584 0,04031104 ! positive regulation of protein complex assembly GO:0031334 26 17 0,000 0,02451149 0,04276895 ! regulation of lipid biosynthetic process GO:0046890 22 17 0,000 0,02451149 0,04273752 ! negative regulation of cell cycle process GO:0010948 37 17 0,000 0,02451149 0,04270615 ! zinc ion transport GO:0006829 22 17 0,000 0,02451149 0,04267481 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02451149 0,04264353 ! protein amino acid deacetylation GO:0006476 23 17 0,000 0,02451149 0,04261229 ! heterophilic cell adhesion GO:0007157 38 17 0,000 0,02451149 0,04258109 ! protein amino acid acetylation GO:0006473 33 17 0,000 0,02451149 0,04254994 ! regulation of neurotransmitter secretion GO:0046928 32 17 0,000 0,02451149 0,04251884 ! forelimb morphogenesis GO:0035136 20 17 0,000 0,02451149 0,04248778 ! negative regulation of ion transport GO:0043271 19 17 0,000 0,02451149 0,04245677 ! regulation of muscle cell differentiation GO:0051147 26 17 0,000 0,02451149 0,0424258 ! adult walking behavior GO:0007628 30 17 0,000 0,02451149 0,04239488 ! patterning of blood vessels GO:0001569 27 17 0,000 0,02451149 0,042364 ! mechanoreceptor differentiation GO:0042490 32 17 0,000 0,02451149 0,04233317 ! cellular response to hydrogen peroxide GO:0070301 25 17 0,000 0,02451149 0,04230238 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 25 17 0,000 0,02451149 0,04227164 ! retinoid metabolic process GO:0001523 22 17 0,000 0,02451149 0,04224094 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 26 17 0,000 0,02451149 0,04221028 ! positive regulation of proteolysis GO:0045862 21 17 0,000 0,02451149 0,04217967 ! cardiac muscle tissue development GO:0048738 27 17 0,000 0,02451149 0,04214911 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02451149 0,04211859 ! protein polyubiquitination GO:0000209 31 17 0,000 0,02451149 0,04208811 ! cerebral cortex development GO:0021987 34 17 0,000 0,02451149 0,04205768 ! complement activation, alternative pathway GO:0006957 17 17 0,000 0,02451149 0,04202729 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02451149 0,04199695 ! fructose metabolic process GO:0006000 24 17 0,000 0,02451149 0,04196665 ! membrane budding GO:0006900 30 17 0,000 0,02451149 0,04193639 ! neuromuscular junction development GO:0007528 25 17 0,000 0,02451149 0,04190617 ! peptide secretion GO:0002790 30 17 0,000 0,02451149 0,041876 ! stem cell differentiation GO:0048863 40 17 0,000 0,02451149 0,04184588 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02451149 0,04181579 ! intermediate filament-based process GO:0045103 29 17 0,000 0,02451149 0,04178575 ! protein export from nucleus GO:0006611 26 17 0,000 0,02451149 0,04175576 ! nucleotide-excision repair, DNA gap filling GO:0006297 23 17 0,000 0,02451149 0,0417258 ! diencephalon development GO:0021536 27 17 0,000 0,02451149 0,04169589 ! oogenesis GO:0048477 25 17 0,000 0,02451149 0,04166602 ! long-chain fatty acid transport GO:0015909 25 17 0,000 0,02451149 0,0416362 ! peptide biosynthetic process GO:0043043 22 17 0,000 0,02451149 0,04160642 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02451149 0,04157668 GO:0046467|membrane lipid biosynthetic process, ! biomineral formation GO:0031214 21 17 0,000 0,02451149 0,04154698 ! vitamin A metabolic process GO:0006776 23 17 0,000 0,02451149 0,04151732 ! steroid catabolic process GO:0006706 24 17 0,000 0,02451149 0,04148771 ! porphyrin biosynthetic process GO:0006779 24 17 0,000 0,02451149 0,04145814 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 23 17 0,000 0,02451149 0,04142861 ! nerve development GO:0021675 20 17 0,000 0,02451149 0,04139912 ! negative regulation of homeostatic process GO:0032845 29 17 0,000 0,02451149 0,04136968 ! regulation of mitotic metaphase/anaphase transition GO:0030071 33 17 0,000 0,02451149 0,04134028 ! protein secretion GO:0009306 32 18 0,000 0,02593513 0,04371028 ! regulation of glucose metabolic process GO:0010906 25 18 0,000 0,02593513 0,04367925 ! positive regulation of cell killing GO:0031343 27 18 0,000 0,02593513 0,04364828 ! negative regulation of defense response GO:0031348 21 18 0,000 0,02593513 0,04361734 ! pteridine and derivative metabolic process GO:0042558 23 18 0,000 0,02593513 0,04358645 ! positive regulation of anti-apoptosis GO:0045768 33 18 0,000 0,02593513 0,04355561 ! metencephalon development GO:0022037 25 18 0,000 0,02593513 0,0435248 ! positive regulation of hormone secretion GO:0046887 28 18 0,000 0,02593513 0,04349404 ! hormone secretion GO:0046879 28 18 0,000 0,02593513 0,04346333 ! 2'-deoxyribonucleotide metabolic process GO:0009394 24 18 0,000 0,02593513 0,04343265 GO:0019692|deoxyribose phosphate metabolic process, ! signal complex assembly GO:0007172 32 18 0,000 0,02593513 0,04340202 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 27 18 0,000 0,02593513 0,04337144 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02593513 0,04334089 ! intra-Golgi vesicle-mediated transport GO:0006891 28 18 0,000 0,02593513 0,04331039 ! protein amino acid ADP-ribosylation GO:0006471 30 18 0,000 0,02593513 0,04327994 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02593513 0,04324952 ! transcription from RNA polymerase III promoter GO:0006383 36 18 0,000 0,02593513 0,04321915 ! regulation of postsynaptic membrane potential GO:0060078 31 18 0,000 0,02593513 0,04318882 ! glial cell development GO:0021782 31 18 0,000 0,02593513 0,04315853 ! keratinization GO:0031424 19 18 0,000 0,02593513 0,04312829 ! regulation of systemic arterial blood pressure by hormone GO:0001990 27 18 0,000 0,02593513 0,04309809 GO:0050886|endocrine process, ! myoblast differentiation GO:0045445 31 18 0,000 0,02593513 0,04306793 ! inactivation of MAPK activity GO:0000188 28 18 0,000 0,02593513 0,04303781 ! negative regulation of epithelial cell proliferation GO:0050680 36 18 0,000 0,02593513 0,04300774 ! vacuolar transport GO:0007034 26 18 0,000 0,02593513 0,0429777 ! pigmentation during development GO:0048066 35 18 0,000 0,02593513 0,04294771 ! cell-substrate junction assembly GO:0007044 45 18 0,000 0,02593513 0,04291776 ! cellular macromolecular complex disassembly GO:0034623 30 18 0,000 0,02593513 0,04288785 ! cellular response to unfolded protein GO:0034620 24 18 0,000 0,02593513 0,04285799 GO:0030968|endoplasmic reticulum unfolded protein response, ! fucose metabolic process GO:0006004 27 18 0,000 0,02593513 0,04282816 ! actin filament bundle formation GO:0051017 30 18 0,000 0,02593513 0,04279838 ! body fluid secretion GO:0007589 27 18 0,000 0,02593513 0,04276864 ! NLS-bearing substrate import into nucleus GO:0006607 40 18 0,000 0,02593513 0,04273894 ! behavioral interaction between organisms GO:0051705 26 18 0,000 0,02593513 0,04270928 ! negative regulation of immune response GO:0050777 33 18 0,000 0,02593513 0,04267966 ! heart process GO:0003015 32 18 0,000 0,02593513 0,04265008 GO:0060047|heart contraction, ! regulation of T cell mediated immunity GO:0002709 39 18 0,000 0,02593513 0,04262055 ! sensory perception of pain GO:0019233 26 18 0,000 0,02593513 0,04259105 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 18 0,000 0,02593513 0,0425616 ! ribosomal small subunit biogenesis GO:0042274 22 18 0,000 0,02593513 0,04253218 ! somitogenesis GO:0001756 25 18 0,000 0,02593513 0,04250281 ! neural crest cell migration GO:0001755 28 18 0,000 0,02593513 0,04247348 ! neutrophil chemotaxis GO:0030593 26 18 0,000 0,02593513 0,04244419 ! positive regulation of intracellular transport GO:0032388 30 18 0,000 0,02593513 0,04241493 ! negative regulation of intracellular transport GO:0032387 31 18 0,000 0,02593513 0,04238572 ! synaptogenesis GO:0007416 28 18 0,000 0,02593513 0,04235655 ! cell-cell junction organization GO:0045216 28 18 0,000 0,02593513 0,04232742 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02593513 0,04229833 ! purine nucleotide catabolic process GO:0006195 27 18 0,000 0,02593513 0,04226928 ! proximal/distal pattern formation GO:0009954 28 18 0,000 0,02593513 0,04224027 ! regulation of generation of precursor metabolites and energy GO:0043467 29 18 0,000 0,02593513 0,0422113 ! aromatic compound catabolic process GO:0019439 26 18 0,000 0,02593513 0,04218236 ! somatic recombination of immunoglobulin gene segments GO:0016447 28 18 0,000 0,02593513 0,04215347 ! gut development GO:0048565 29 18 0,000 0,02593513 0,04212462 ! negative regulation of leukocyte proliferation GO:0070664 35 18 0,000 0,02593513 0,04209581 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! antigen receptor-mediated signaling pathway GO:0050851 33 18 0,000 0,02593513 0,04206703 ! positive regulation of synaptic transmission GO:0050806 26 18 0,000 0,02593513 0,0420383 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 28 19 0,000 0,02735677 0,04431236 ! positive regulation of translation GO:0045727 29 19 0,000 0,02735677 0,04428213 ! positive regulation of cell size GO:0045793 26 19 0,000 0,02735677 0,04425195 ! phosphatidylinositol metabolic process GO:0046488 24 19 0,000 0,02735677 0,0442218 ! glycerol metabolic process GO:0006071 22 19 0,000 0,02735677 0,0441917 ! phosphoinositide phosphorylation GO:0046854 26 19 0,000 0,02735677 0,04416164 ! regulation of neuronal synaptic plasticity GO:0048168 37 19 0,000 0,02735677 0,04413162 ! endothelial cell migration GO:0043542 24 19 0,000 0,02735677 0,04410164 ! glycosaminoglycan biosynthetic process GO:0006024 27 19 0,000 0,02735677 0,0440717 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 23 19 0,000 0,02735677 0,0440418 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 19 0,000 0,02735677 0,04401194 ! memory GO:0007613 28 19 0,000 0,02735677 0,04398212 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 19 0,000 0,02735677 0,04395234 ! pancreas development GO:0031016 27 19 0,000 0,02735677 0,0439226 ! response to carbohydrate stimulus GO:0009743 28 19 0,000 0,02735677 0,04389291 ! DNA duplex unwinding GO:0032508 28 19 0,000 0,02735677 0,04386325 GO:0032392|DNA geometric change, ! peroxisome organization GO:0007031 30 19 0,000 0,02735677 0,04383363 ! central nervous system neuron development GO:0021954 33 19 0,000 0,02735677 0,04380405 ! polysaccharide catabolic process GO:0000272 24 19 0,000 0,02735677 0,04377452 ! actin polymerization or depolymerization GO:0008154 32 19 0,000 0,02735677 0,04374502 ! vesicle docking during exocytosis GO:0006904 25 19 0,000 0,02735677 0,04371556 ! heme metabolic process GO:0042168 29 19 0,000 0,02735677 0,04368614 ! negative regulation of protein catabolic process GO:0042177 29 19 0,000 0,02735677 0,04365676 ! response to lipopolysaccharide GO:0032496 28 19 0,000 0,02735677 0,04362743 ! response to fungus GO:0009620 21 19 0,000 0,02735677 0,04359813 ! peptide cross-linking GO:0018149 35 19 0,000 0,02735677 0,04356887 ! ventricular cardiac muscle morphogenesis GO:0055010 25 19 0,000 0,02735677 0,04353964 ! determination of left/right symmetry GO:0007368 24 19 0,000 0,02735677 0,04351046 ! prostaglandin metabolic process GO:0006693 34 19 0,000 0,02735677 0,04348132 GO:0006692|prostanoid metabolic process, ! regulation of immunoglobulin mediated immune response GO:0002889 29 19 0,000 0,02735677 0,04345221 GO:0002712|regulation of B cell mediated immunity, ! detection of chemical stimulus GO:0009593 28 19 0,000 0,02735677 0,04342315 ! vitamin transport GO:0051180 26 19 0,000 0,02735677 0,04339412 ! sarcomere organization GO:0045214 26 19 0,000 0,02735677 0,04336514 ! positive regulation of myeloid cell differentiation GO:0045639 50 19 0,000 0,02735677 0,04333619 ! regulation of immunoglobulin production GO:0002637 29 19 0,000 0,02735677 0,04330728 ! positive regulation of transmission of nerve impulse GO:0051971 27 19 0,000 0,02735677 0,04327841 ! leukotriene biosynthetic process GO:0019370 27 19 0,000 0,02735677 0,04324957 GO:0043450|alkene biosynthetic process, ! regulation of glucose import GO:0046324 23 19 0,000 0,02735677 0,04322078 GO:0010827|regulation of glucose transport, ! negative regulation of coagulation GO:0050819 25 19 0,000 0,02735677 0,04319202 ! oligosaccharide metabolic process GO:0009311 35 20 0,000 0,0287764 0,04540319 ! positive regulation of angiogenesis GO:0045766 42 20 0,000 0,0287764 0,04537302 ! determination of bilateral symmetry GO:0009855 26 20 0,000 0,0287764 0,04534289 GO:0009799|determination of symmetry, ! N-acetylglucosamine metabolic process GO:0006044 25 20 0,000 0,0287764 0,0453128 ! lipid phosphorylation GO:0046834 28 20 0,000 0,0287764 0,04528275 ! aminoglycan biosynthetic process GO:0006023 28 20 0,000 0,0287764 0,04525275 ! hindlimb morphogenesis GO:0035137 35 20 0,000 0,0287764 0,04522278 ! C21-steroid hormone metabolic process GO:0008207 25 20 0,000 0,0287764 0,04519285 ! calcium-independent cell-cell adhesion GO:0016338 23 20 0,000 0,0287764 0,04516296 ! response to alkaloid GO:0043279 34 20 0,000 0,0287764 0,04513311 ! sensory perception of taste GO:0050909 26 20 0,000 0,0287764 0,0451033 ! response to retinoic acid GO:0032526 27 20 0,000 0,0287764 0,04507353 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 20 0,000 0,0287764 0,0450438 ! cellular response to reactive oxygen species GO:0034614 32 20 0,000 0,0287764 0,0450141 ! D-ribose metabolic process GO:0006014 27 20 0,000 0,0287764 0,04498445 ! chromosome condensation GO:0030261 32 20 0,000 0,0287764 0,04495483 ! peptidyl-serine phosphorylation GO:0018105 31 20 0,000 0,0287764 0,04492526 ! sex determination GO:0007530 32 20 0,000 0,0287764 0,04489572 ! plasma membrane fusion GO:0045026 24 20 0,000 0,0287764 0,04486622 ! fatty acid beta-oxidation GO:0006635 32 20 0,000 0,0287764 0,04483677 ! positive regulation of alpha-beta T cell differentiation GO:0046638 29 20 0,000 0,0287764 0,04480735 ! cytolysis GO:0019835 21 20 0,000 0,0287764 0,04477796 ! renal system process GO:0003014 35 20 0,000 0,0287764 0,04474862 ! vasodilation GO:0042311 36 20 0,000 0,0287764 0,04471932 ! negative regulation of angiogenesis GO:0016525 38 20 0,000 0,0287764 0,04469005 ! detection of biotic stimulus GO:0009595 23 20 0,000 0,0287764 0,04466082 ! cellular response to nutrient levels GO:0031669 32 20 0,000 0,0287764 0,04463163 ! positive regulation of neurological system process GO:0031646 31 20 0,000 0,0287764 0,04460248 ! hormone transport GO:0009914 30 20 0,000 0,0287764 0,04457336 ! negative regulation of neuron differentiation GO:0045665 33 20 0,000 0,0287764 0,04454429 ! activation of JUN kinase activity GO:0007257 28 20 0,000 0,0287764 0,04451525 ! regulation of leukocyte mediated cytotoxicity GO:0001910 34 20 0,000 0,0287764 0,04448625 ! estrogen receptor signaling pathway GO:0030520 36 20 0,000 0,0287764 0,04445729 ! sperm-egg recognition GO:0035036 24 20 0,000 0,0287764 0,04442836 GO:0007339|binding of sperm to zona pellucida, ! embryonic organ morphogenesis GO:0048562 26 20 0,000 0,0287764 0,04439948 ! cellular monovalent inorganic cation homeostasis GO:0030004 31 20 0,000 0,0287764 0,04437063 ! positive regulation of DNA replication GO:0045740 37 21 0,000 0,03019403 0,04652625 ! positive regulation of protein catabolic process GO:0045732 25 21 0,000 0,03019403 0,04649606 ! positive regulation of fibroblast proliferation GO:0048146 30 21 0,000 0,03019403 0,04646591 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,03019403 0,04643579 ! positive regulation of ossification GO:0045778 34 21 0,000 0,03019403 0,04640572 ! G2/M transition of mitotic cell cycle GO:0000086 34 21 0,000 0,03019403 0,04637568 ! iron ion transport GO:0006826 49 21 0,000 0,03019403 0,04634569 ! glucosamine metabolic process GO:0006041 26 21 0,000 0,03019403 0,04631573 ! microtubule-based transport GO:0010970 41 21 0,000 0,03019403 0,04628581 ! vesicle docking GO:0048278 28 21 0,000 0,03019403 0,04625593 ! regulation of carbohydrate metabolic process GO:0006109 31 21 0,000 0,03019403 0,04622608 GO:0010675|regulation of cellular carbohydrate metabolic process, ! ovarian follicle development GO:0001541 33 21 0,000 0,03019403 0,04619628 ! apoptotic mitochondrial changes GO:0008637 42 21 0,000 0,03019403 0,04616652 ! response to ethanol GO:0045471 38 21 0,000 0,03019403 0,04613679 ! positive regulation of epithelial cell proliferation GO:0050679 43 21 0,000 0,03019403 0,0461071 ! smooth muscle contraction GO:0006939 39 21 0,000 0,03019403 0,04607745 ! glutamine metabolic process GO:0006541 29 21 0,000 0,03019403 0,04604784 ! response to vitamin A GO:0033189 28 21 0,000 0,03019403 0,04601826 ! purine ribonucleoside metabolic process GO:0046128 30 21 0,000 0,03019403 0,04598872 GO:0042278|purine nucleoside metabolic process, ! neurotransmitter metabolic process GO:0042133 36 21 0,000 0,03019403 0,04595922 ! response to starvation GO:0042594 35 21 0,000 0,03019403 0,04592976 ! regulation of myeloid leukocyte differentiation GO:0002761 41 21 0,000 0,03019403 0,04590034 ! leukotriene metabolic process GO:0006691 29 21 0,000 0,03019403 0,04587095 ! regulation of vasoconstriction GO:0019229 33 21 0,000 0,03019403 0,04584161 ! glycosphingolipid metabolic process GO:0006687 35 21 0,000 0,03019403 0,0458123 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 28 21 0,000 0,03019403 0,04578302 ! regulation of fatty acid metabolic process GO:0019217 32 21 0,000 0,03019403 0,04575379 ! visual learning GO:0008542 38 21 0,000 0,03019403 0,04572459 ! negative regulation of Wnt receptor signaling pathway GO:0030178 32 21 0,000 0,03019403 0,04569543 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 38 21 0,000 0,03019403 0,0456663 ! positive regulation of inflammatory response GO:0050729 38 21 0,000 0,03019403 0,04563722 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,03019403 0,04560817 ! neuromuscular process controlling balance GO:0050885 54 21 0,000 0,03019403 0,04557915 ! negative regulation of myeloid cell differentiation GO:0045638 29 21 0,000 0,03019403 0,04555018 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,03019403 0,04552124 ! aromatic amino acid family metabolic process GO:0009072 30 21 0,000 0,03019403 0,04549234 ! somatic diversification of immunoglobulins GO:0016445 31 21 0,000 0,03019403 0,04546347 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,03019403 0,04543464 ! negative regulation of T cell activation GO:0050868 35 21 0,000 0,03019403 0,04540585 ! regulation of microtubule polymerization or depolymerization GO:0031110 51 21 0,000 0,03019403 0,04537709 ! embryonic pattern specification GO:0009880 34 22 0,000 0,03160966 0,04747451 ! regulation of cell killing GO:0031341 37 22 0,000 0,03160966 0,04744448 ! regulation of anti-apoptosis GO:0045767 40 22 0,000 0,03160966 0,04741449 ! gluconeogenesis GO:0006094 26 22 0,000 0,03160966 0,04738454 ! viral genome replication GO:0019079 31 22 0,000 0,03160966 0,04735463 ! nucleotide-excision repair, DNA damage removal GO:0000718 27 22 0,000 0,03160966 0,04732475 ! protein amino acid O-linked glycosylation GO:0006493 36 22 0,000 0,03160966 0,04729491 ! protein amino acid acylation GO:0043543 42 22 0,000 0,03160966 0,04726511 ! response to vitamin GO:0033273 31 22 0,000 0,03160966 0,04723534 ! molting cycle process GO:0022404 43 22 0,000 0,03160966 0,04720562 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of neurotransmitter transport GO:0051588 41 22 0,000 0,03160966 0,04717593 ! regeneration GO:0031099 37 22 0,000 0,03160966 0,04714628 ! phototransduction GO:0007602 29 22 0,000 0,03160966 0,04711666 ! regulation of DNA recombination GO:0000018 43 22 0,000 0,03160966 0,04708709 ! regulation of smooth muscle contraction GO:0006940 38 22 0,000 0,03160966 0,04705755 ! deoxyribonucleotide metabolic process GO:0009262 29 22 0,000 0,03160966 0,04702804 ! central nervous system neuron differentiation GO:0021953 39 22 0,000 0,03160966 0,04699858 ! cholesterol biosynthetic process GO:0006695 32 22 0,000 0,03160966 0,04696915 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 22 0,000 0,03160966 0,04693975 ! regulation of interleukin-6 production GO:0032675 25 22 0,000 0,03160966 0,0469104 ! regulation of interleukin-2 production GO:0032663 38 22 0,000 0,03160966 0,04688108 ! pallium development GO:0021543 43 22 0,000 0,03160966 0,0468518 ! positive regulation of locomotion GO:0040017 40 22 0,000 0,03160966 0,04682255 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! fatty acid transport GO:0015908 33 22 0,000 0,03160966 0,04679334 ! platelet activation GO:0030168 33 22 0,000 0,03160966 0,04676417 ! proteoglycan biosynthetic process GO:0030166 33 22 0,000 0,03160966 0,04673503 ! regulation of cytokine secretion GO:0050707 30 22 0,000 0,03160966 0,04670593 ! positive regulation of osteoblast differentiation GO:0045669 37 22 0,000 0,03160966 0,04667687 ! cellular alkene metabolic process GO:0043449 30 22 0,000 0,03160966 0,04664784 ! cell-cell recognition GO:0009988 28 22 0,000 0,03160966 0,04661885 ! pyrimidine nucleoside metabolic process GO:0006213 28 22 0,000 0,03160966 0,04658989 ! water-soluble vitamin biosynthetic process GO:0042364 28 22 0,000 0,03160966 0,04656097 ! neural tube closure GO:0001843 35 22 0,000 0,03160966 0,04653209 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 26 22 0,000 0,03160966 0,04650324 ! regulation of multi-organism process GO:0043900 35 22 0,000 0,03160966 0,04647443 ! protein tetramerization GO:0051262 43 22 0,000 0,03160966 0,04644565 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 36 23 0,000 0,0330233 0,04849275 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid metabolic process GO:0000096 31 23 0,000 0,0330233 0,04846276 ! reciprocal meiotic recombination GO:0007131 41 23 0,000 0,0330233 0,04843281 ! cellular aldehyde metabolic process GO:0006081 32 23 0,000 0,0330233 0,0484029 ! positive regulation of bone remodeling GO:0046852 37 23 0,000 0,0330233 0,04837302 ! cellular polysaccharide biosynthetic process GO:0033692 29 23 0,000 0,0330233 0,04834318 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 31 23 0,000 0,0330233 0,04831337 ! dicarboxylic acid metabolic process GO:0043648 36 23 0,000 0,0330233 0,0482836 ! regulation of chemotaxis GO:0050920 41 23 0,000 0,0330233 0,04825387 ! regulation of receptor-mediated endocytosis GO:0048259 26 23 0,000 0,0330233 0,04822418 ! tube lumen formation GO:0035148 37 23 0,000 0,0330233 0,04819452 ! macromolecular complex disassembly GO:0032984 39 23 0,000 0,0330233 0,0481649 ! dendrite development GO:0016358 41 23 0,000 0,0330233 0,04813531 ! vasculogenesis GO:0001570 38 23 0,000 0,0330233 0,04810576 ! microtubule organizing center organization GO:0031023 30 23 0,000 0,0330233 0,04807625 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 50 23 0,000 0,0330233 0,04804677 ! lysosome organization GO:0007040 41 23 0,000 0,0330233 0,04801733 ! digestive system process GO:0022600 35 23 0,000 0,0330233 0,04798793 ! positive regulation of cytoskeleton organization GO:0051495 43 23 0,000 0,0330233 0,04795856 ! vesicle targeting GO:0006903 35 23 0,000 0,0330233 0,04792923 ! response to corticosteroid stimulus GO:0031960 37 23 0,000 0,0330233 0,04789993 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 36 23 0,000 0,0330233 0,04787067 ! regulation of endothelial cell migration GO:0010594 44 23 0,000 0,0330233 0,04784145 ! regulation of viral reproduction GO:0050792 33 23 0,000 0,0330233 0,04781226 ! regulation of insulin secretion GO:0050796 30 23 0,000 0,0330233 0,0477831 ! regulation of alpha-beta T cell differentiation GO:0046637 35 23 0,000 0,0330233 0,04775398 ! cardiac muscle tissue morphogenesis GO:0055008 29 23 0,000 0,0330233 0,0477249 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 42 23 0,000 0,0330233 0,04769585 ! membrane depolarization GO:0051899 40 23 0,000 0,0330233 0,04766684 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,0330233 0,04763787 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 39 23 0,000 0,0330233 0,04760892 ! regulation of ARF GTPase activity GO:0032312 35 23 0,000 0,0330233 0,04758002 ! DNA modification GO:0006304 33 23 0,000 0,0330233 0,04755115 ! collagen fibril organization GO:0030199 50 23 0,000 0,0330233 0,04752231 ! synaptic vesicle transport GO:0048489 45 23 0,000 0,0330233 0,04749351 ! cellular response to extracellular stimulus GO:0031668 37 23 0,000 0,0330233 0,04746474 ! peptidyl-serine modification GO:0018209 37 23 0,000 0,0330233 0,04743601 ! nerve-nerve synaptic transmission GO:0007270 42 23 0,000 0,0330233 0,04740731 ! fat-soluble vitamin metabolic process GO:0006775 29 23 0,000 0,0330233 0,04737865 ! positive regulation of B cell activation GO:0050871 36 23 0,000 0,0330233 0,04735002 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,0330233 0,04732143 ! collagen catabolic process GO:0030574 29 23 0,000 0,0330233 0,04729287 ! glutamine family amino acid catabolic process GO:0009065 34 23 0,000 0,0330233 0,04726435 ! aspartate family amino acid metabolic process GO:0009066 27 23 0,000 0,0330233 0,04723586 ! porphyrin metabolic process GO:0006778 37 23 0,000 0,0330233 0,0472074 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 39 23 0,000 0,0330233 0,04717898 ! blastocyst development GO:0001824 41 23 0,000 0,0330233 0,0471506 ! actin filament-based movement GO:0030048 37 23 0,000 0,0330233 0,04712224 ! protein stabilization GO:0050821 34 23 0,000 0,0330233 0,04709392 ! protein import into nucleus, docking GO:0000059 45 24 0,000 0,03443494 0,04907755 ! myelination GO:0042552 39 24 0,000 0,03443494 0,04904809 ! initiation of viral infection GO:0019059 47 24 0,000 0,03443494 0,04901867 ! regulation of transmembrane transport GO:0034762 31 24 0,000 0,03443494 0,04898928 ! leukocyte adhesion GO:0007159 49 24 0,000 0,03443494 0,04895993 ! glutamate signaling pathway GO:0007215 37 24 0,000 0,03443494 0,04893061 ! regulation of transcription factor import into nucleus GO:0042990 49 24 0,000 0,03443494 0,04890133 ! visual behavior GO:0007632 42 24 0,000 0,03443494 0,04887208 ! spinal cord development GO:0021510 41 24 0,000 0,03443494 0,04884287 ! immune response-activating cell surface receptor signaling pathway GO:0002429 39 24 0,000 0,03443494 0,04881369 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 46 24 0,000 0,03443494 0,04878455 ! multicellular organismal response to stress GO:0033555 42 24 0,000 0,03443494 0,04875544 ! regulation of nitric oxide biosynthetic process GO:0045428 42 24 0,000 0,03443494 0,04872637 ! negative regulation of DNA replication GO:0008156 39 24 0,000 0,03443494 0,04869733 ! cell aging GO:0007569 38 24 0,000 0,03443494 0,04866833 ! osteoblast differentiation GO:0001649 43 24 0,000 0,03443494 0,04863936 ! response to endoplasmic reticulum stress GO:0034976 32 24 0,000 0,03443494 0,04861042 ! response to toxin GO:0009636 38 24 0,000 0,03443494 0,04858152 ! primary neural tube formation GO:0014020 37 24 0,000 0,03443494 0,04855266 ! vitamin biosynthetic process GO:0009110 30 24 0,000 0,03443494 0,04852383 ! positive regulation of alpha-beta T cell activation GO:0046635 40 24 0,000 0,03443494 0,04849503 ! cellular response to oxidative stress GO:0034599 38 24 0,000 0,03443494 0,04846626 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 24 0,000 0,03443494 0,04843754 ! fibroblast growth factor receptor signaling pathway GO:0008543 45 24 0,000 0,03443494 0,04840884 ! pentose metabolic process GO:0019321 33 24 0,000 0,03443494 0,04838018 ! immunoglobulin production GO:0002377 37 24 0,000 0,03443494 0,04835155 GO:0002440|production of molecular mediator of immune response, ! regulation of response to biotic stimulus GO:0002831 45 24 0,000 0,03443494 0,04832296 ! positive regulation of protein secretion GO:0050714 29 24 0,000 0,03443494 0,0482944 ! positive regulation of adaptive immune response GO:0002821 44 24 0,000 0,03443494 0,04826587 ! regulation of blood coagulation GO:0030193 37 24 0,000 0,03443494 0,04823738 ! positive regulation of tissue remodeling GO:0034105 41 24 0,000 0,03443494 0,04820892 ! group transfer coenzyme metabolic process GO:0006752 29 24 0,000 0,03443494 0,0481805 ! response to molecule of bacterial origin GO:0002237 38 24 0,000 0,03443494 0,04815211 ! positive regulation of JUN kinase activity GO:0043507 33 24 0,000 0,03443494 0,04812375 ! regulation of fibroblast proliferation GO:0048145 39 25 0,000 0,0358446 0,05006429 ! neuron fate commitment GO:0048663 38 25 0,000 0,0358446 0,05003484 ! pyruvate metabolic process GO:0006090 32 25 0,000 0,0358446 0,05000543 ! superoxide metabolic process GO:0006801 33 25 0,000 0,0358446 0,04997605 ! detection of light stimulus involved in sensory perception GO:0050962 32 25 0,000 0,0358446 0,0499467 GO:0050908|detection of light stimulus involved in visual perception, ! activation of pro-apoptotic gene products GO:0008633 44 25 0,000 0,0358446 0,04991739 ! mitochondrial membrane organization GO:0007006 42 25 0,000 0,0358446 0,04988811 ! vacuole organization GO:0007033 43 25 0,000 0,0358446 0,04985887 ! receptor metabolic process GO:0043112 40 25 0,000 0,0358446 0,04982966 ! barbed-end actin filament capping GO:0051016 41 25 0,000 0,0358446 0,04980049 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 35 25 0,000 0,0358446 0,04977135 ! regulation of behavior GO:0050795 45 25 0,000 0,0358446 0,04974224 ! hydrogen peroxide metabolic process GO:0042743 35 25 0,000 0,0358446 0,04971317 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 45 25 0,000 0,0358446 0,04968413 ! lymphocyte proliferation GO:0046651 42 25 0,000 0,0358446 0,04965513 ! negative regulation of phosphorylation GO:0042326 46 25 0,000 0,0358446 0,04962616 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,0358446 0,04959722 ! regulation of tumor necrosis factor production GO:0032680 32 25 0,000 0,0358446 0,04956832 ! leukocyte homeostasis GO:0001776 40 25 0,000 0,0358446 0,04953945 ! positive regulation of nuclear division GO:0051785 41 25 0,000 0,0358446 0,04951061 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 38 25 0,000 0,0358446 0,04948181 ! camera-type eye morphogenesis GO:0048593 43 25 0,000 0,0358446 0,04945304 ! negative regulation of catabolic process GO:0009895 37 25 0,000 0,0358446 0,04942431 ! regulation of amine transport GO:0051952 44 25 0,000 0,0358446 0,04939561 ! liver development GO:0001889 44 25 0,000 0,0358446 0,04936694 ! positive regulation of cell projection organization GO:0031346 43 26 0,000 0,03725227 0,05127589 ! regulation of cellular catabolic process GO:0031329 39 26 0,000 0,03725227 0,05124616 ! regulation of interferon-gamma production GO:0032649 33 26 0,000 0,03725227 0,05121647 ! cellular iron ion homeostasis GO:0006879 47 26 0,000 0,03725227 0,05118681 ! epidermal growth factor receptor signaling pathway GO:0007173 42 26 0,000 0,03725227 0,05115719 ! amino sugar metabolic process GO:0006040 32 26 0,000 0,03725227 0,05112761 ! protein amino acid alkylation GO:0008213 40 26 0,000 0,03725227 0,05109805 GO:0006479|protein amino acid methylation, ! odontogenesis of dentine-containing tooth GO:0042475 43 26 0,000 0,03725227 0,05106853 ! insulin receptor signaling pathway GO:0008286 48 26 0,000 0,03725227 0,05103905 ! sperm motility GO:0030317 31 26 0,000 0,03725227 0,0510096 ! ER-nuclear signaling pathway GO:0006984 33 26 0,000 0,03725227 0,05098018 ! peptidyl-tyrosine phosphorylation GO:0018108 42 26 0,000 0,03725227 0,0509508 ! male gonad development GO:0008584 39 26 0,000 0,03725227 0,05092145 ! neural crest cell development GO:0014032 44 26 0,000 0,03725227 0,05089213 GO:0014033|neural crest cell differentiation, ! base-excision repair GO:0006284 35 26 0,000 0,03725227 0,05086285 ! cell fate determination GO:0001709 54 26 0,000 0,03725227 0,0508336 ! regulation of chromosome organization GO:0033044 37 26 0,000 0,03725227 0,05080438 ! regulation of oxidoreductase activity GO:0051341 42 26 0,000 0,03725227 0,0507752 ! detection of visible light GO:0009584 33 26 0,000 0,03725227 0,05074606 ! spermatid development GO:0007286 40 26 0,000 0,03725227 0,05071694 ! regulation of bone mineralization GO:0030500 38 26 0,000 0,03725227 0,05068786 ! regulation of osteoblast differentiation GO:0045667 41 26 0,000 0,03725227 0,05065881 ! acetyl-CoA catabolic process GO:0046356 38 26 0,000 0,03725227 0,0506298 GO:0006099|tricarboxylic acid cycle, ! regulation of JUN kinase activity GO:0043506 39 26 0,000 0,03725227 0,05060082 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,03865795 0,05248016 ! spliceosomal snRNP biogenesis GO:0000387 38 27 0,000 0,03865795 0,05245015 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 47 27 0,000 0,03865795 0,05242018 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 42 27 0,000 0,03865795 0,05239024 ! membrane docking GO:0022406 40 27 0,000 0,03865795 0,05236034 ! circadian rhythm GO:0007623 44 27 0,000 0,03865795 0,05233047 ! regulation of endothelial cell proliferation GO:0001936 52 27 0,000 0,03865795 0,05230064 ! fat cell differentiation GO:0045444 41 27 0,000 0,03865795 0,05227084 ! positive regulation of innate immune response GO:0045089 34 27 0,000 0,03865795 0,05224107 ! autophagy GO:0006914 36 27 0,000 0,03865795 0,05221134 ! myofibril assembly GO:0030239 40 27 0,000 0,03865795 0,05218164 GO:0055002|striated muscle cell development, ! negative regulation of phosphorus metabolic process GO:0010563 51 27 0,000 0,03865795 0,05215197 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 38 27 0,000 0,03865795 0,05212234 ! peptide transport GO:0015833 46 27 0,000 0,03865795 0,05209274 ! coenzyme catabolic process GO:0009109 40 27 0,000 0,03865795 0,05206318 ! regulation of peptide secretion GO:0002791 39 27 0,000 0,03865795 0,05203365 ! negative regulation of cell development GO:0010721 67 27 0,000 0,03865795 0,05200415 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 46 27 0,000 0,03865795 0,05197468 ! positive regulation of leukocyte mediated immunity GO:0002705 45 27 0,000 0,03865795 0,05194525 GO:0002708|positive regulation of lymphocyte mediated immunity, ! phospholipid transport GO:0015914 40 27 0,000 0,03865795 0,05191586 ! detection of light stimulus GO:0009583 35 27 0,000 0,03865795 0,05188649 ! glutathione metabolic process GO:0006749 35 27 0,000 0,03865795 0,05185716 ! lipid oxidation GO:0034440 39 27 0,000 0,03865795 0,05182786 GO:0019395|fatty acid oxidation, ! leukocyte proliferation GO:0070661 45 27 0,000 0,03865795 0,0517986 GO:0032943|mononuclear cell proliferation, ! telomere organization GO:0032200 39 27 0,000 0,03865795 0,05176937 GO:0000723|telomere maintenance, ! negative regulation of neuron apoptosis GO:0043524 48 27 0,000 0,03865795 0,05174017 ! protein import into nucleus, translocation GO:0000060 47 28 0,000 0,04006165 0,05358867 ! positive regulation of smooth muscle cell proliferation GO:0048661 45 28 0,000 0,04006165 0,05355848 ! translational initiation GO:0006413 48 28 0,000 0,04006165 0,05352832 ! negative regulation of actin filament depolymerization GO:0030835 44 28 0,000 0,04006165 0,0534982 ! acetyl-CoA metabolic process GO:0006084 42 28 0,000 0,04006165 0,05346811 ! regulation of pH GO:0006885 40 28 0,000 0,04006165 0,05343806 ! catechol metabolic process GO:0009712 46 28 0,000 0,04006165 0,05340803 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 43 28 0,000 0,04006165 0,05337805 ! cellular carbohydrate biosynthetic process GO:0034637 37 28 0,000 0,04006165 0,05334809 ! iron ion homeostasis GO:0055072 49 28 0,000 0,04006165 0,05331817 ! regulation of biomineral formation GO:0070167 40 28 0,000 0,04006165 0,05328828 ! peptidyl-tyrosine modification GO:0018212 44 28 0,000 0,04006165 0,05325843 ! neurotransmitter secretion GO:0007269 41 28 0,000 0,04006165 0,05322861 ! negative regulation of transcription regulator activity GO:0090048 48 28 0,000 0,04006165 0,05319883 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of lymphocyte activation GO:0051250 48 28 0,000 0,04006165 0,05316907 ! gene silencing GO:0016458 47 28 0,000 0,04006165 0,05313935 ! regulation of coagulation GO:0050818 42 28 0,000 0,04006165 0,05310966 ! negative regulation of actin filament polymerization GO:0030837 45 29 0,000 0,04146337 0,05493724 ! phenol metabolic process GO:0018958 47 29 0,000 0,04146337 0,05490658 ! icosanoid biosynthetic process GO:0046456 45 29 0,000 0,04146337 0,05487596 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 39 29 0,000 0,04146337 0,05484537 ! calcium-dependent cell-cell adhesion GO:0016339 36 29 0,000 0,04146337 0,05481481 ! negative regulation of response to external stimulus GO:0032102 39 29 0,000 0,04146337 0,05478429 ! cholesterol transport GO:0030301 48 29 0,000 0,04146337 0,05475381 GO:0015918|sterol transport, ! cholesterol homeostasis GO:0042632 53 29 0,000 0,04146337 0,05472335 GO:0055092|sterol homeostasis, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 39 29 0,000 0,04146337 0,05469293 ! GPI anchor metabolic process GO:0006505 47 29 0,000 0,04146337 0,05466255 ! complement activation, classical pathway GO:0006958 39 29 0,000 0,04146337 0,0546322 ! multicellular organismal catabolic process GO:0044243 36 29 0,000 0,04146337 0,05460188 ! respiratory gaseous exchange GO:0007585 51 29 0,000 0,04146337 0,0545716 ! triglyceride metabolic process GO:0006641 38 29 0,000 0,04146337 0,05454135 ! response to ionizing radiation GO:0010212 55 29 0,000 0,04146337 0,05451113 ! muscle cell development GO:0055001 42 29 0,000 0,04146337 0,05448095 ! response to organic cyclic substance GO:0014070 53 29 0,000 0,04146337 0,0544508 ! regulation of systemic arterial blood pressure GO:0003073 52 29 0,000 0,04146337 0,05442068 ! mesoderm formation GO:0001707 52 29 0,000 0,04146337 0,0543906 ! response to estradiol stimulus GO:0032355 38 29 0,000 0,04146337 0,05436055 ! positive regulation of MAPKKK cascade GO:0043410 45 29 0,000 0,04146337 0,05433053 ! regulation of microtubule cytoskeleton organization GO:0070507 61 29 0,000 0,04146337 0,05430055 ! ensheathment of neurons GO:0007272 48 29 0,000 0,04146337 0,05427059 GO:0008366|axon ensheathment, ! serine family amino acid metabolic process GO:0009069 41 29 0,000 0,04146337 0,05424068 ! spermatid differentiation GO:0048515 45 29 0,000 0,04146337 0,05421079 ! myeloid leukocyte activation GO:0002274 44 29 0,000 0,04146337 0,05418094 ! neural tube formation GO:0001841 46 29 0,000 0,04146337 0,05415112 ! regulation of actin filament depolymerization GO:0030834 47 30 0,000 0,04286312 0,0559484 ! cell junction assembly GO:0034329 65 30 0,000 0,04286312 0,05591764 ! acute-phase response GO:0006953 49 30 0,000 0,04286312 0,05588692 ! segmentation GO:0035282 43 30 0,000 0,04286312 0,05585623 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 56 30 0,000 0,04286312 0,05582557 ! negative regulation of protein kinase cascade GO:0010741 58 30 0,000 0,04286312 0,05579495 ! immune response-activating signal transduction GO:0002757 45 30 0,000 0,04286312 0,05576436 ! regulation of protein import into nucleus GO:0042306 56 30 0,000 0,04286312 0,0557338 ! regulation of production of molecular mediator of immune response GO:0002700 47 30 0,000 0,04286312 0,05570328 ! ceramide metabolic process GO:0006672 47 30 0,000 0,04286312 0,05567279 ! formation of primary germ layer GO:0001704 54 30 0,000 0,04286312 0,05564233 ! nicotinamide metabolic process GO:0006769 47 30 0,000 0,04286312 0,05561191 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 50 30 0,000 0,04286312 0,05558152 ! fatty acid catabolic process GO:0009062 45 30 0,000 0,04286312 0,05555117 ! regulation of calcium ion transport GO:0051924 40 30 0,000 0,04286312 0,05552084 ! negative regulation of protein polymerization GO:0032272 47 30 0,000 0,04286312 0,05549055 ! negative regulation of protein transport GO:0051224 53 30 0,000 0,04286312 0,0554603 ! establishment of vesicle localization GO:0051650 48 30 0,000 0,04286312 0,05543007 ! alkaloid metabolic process GO:0009820 48 31 0,000 0,04426089 0,05720648 ! response to hydrogen peroxide GO:0042542 48 31 0,000 0,04426089 0,05717534 ! post-embryonic development GO:0009791 50 31 0,000 0,04426089 0,05714423 ! inner ear morphogenesis GO:0042472 43 31 0,000 0,04426089 0,05711316 ! regulation of innate immune response GO:0045088 42 31 0,000 0,04426089 0,05708212 ! ovulation cycle process GO:0022602 46 31 0,000 0,04426089 0,05705111 ! mesoderm morphogenesis GO:0048332 54 31 0,000 0,04426089 0,05702014 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 42 31 0,000 0,04426089 0,0569892 ! immune response-regulating signal transduction GO:0002764 51 31 0,000 0,04426089 0,0569583 ! positive regulation of neurogenesis GO:0050769 49 31 0,000 0,04426089 0,05692743 ! positive regulation of T cell differentiation GO:0045582 45 31 0,000 0,04426089 0,05689659 ! positive regulation of multicellular organism growth GO:0040018 42 31 0,000 0,04426089 0,05686578 ! hexose biosynthetic process GO:0019319 37 31 0,000 0,04426089 0,05683501 ! negative regulation of MAP kinase activity GO:0043407 57 31 0,000 0,04426089 0,05680427 ! sterol biosynthetic process GO:0016126 48 31 0,000 0,04426089 0,05677357 ! biogenic amine biosynthetic process GO:0042401 45 31 0,000 0,04426089 0,0567429 ! embryonic epithelial tube formation GO:0001838 50 31 0,000 0,04426089 0,05671226 ! tissue homeostasis GO:0001894 45 31 0,000 0,04426089 0,05668165 GO:0048871|multicellular organismal homeostasis, ! mitotic sister chromatid segregation GO:0000070 47 32 0,000 0,0456567 0,05843761 ! DNA damage checkpoint GO:0000077 57 32 0,000 0,0456567 0,05840611 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 49 32 0,000 0,0456567 0,05837464 ! negative regulation of protein complex assembly GO:0031333 51 32 0,000 0,0456567 0,05834321 ! regulation of synaptic plasticity GO:0048167 54 32 0,000 0,0456567 0,05831181 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 32 0,000 0,0456567 0,05828044 ! positive regulation of endocytosis GO:0045807 39 32 0,000 0,0456567 0,05824911 ! positive regulation of T cell proliferation GO:0042102 56 32 0,000 0,0456567 0,05821781 ! regulation of striated muscle tissue development GO:0016202 51 32 0,000 0,0456567 0,05818654 ! unsaturated fatty acid biosynthetic process GO:0006636 50 32 0,000 0,0456567 0,05815531 ! regulation of axonogenesis GO:0050770 60 32 0,000 0,0456567 0,05812411 ! telencephalon development GO:0021537 59 32 0,000 0,0456567 0,05809294 ! ovulation cycle GO:0042698 48 32 0,000 0,0456567 0,05806181 ! cofactor catabolic process GO:0051187 52 32 0,000 0,0456567 0,05803071 ! pyridine nucleotide metabolic process GO:0019362 49 32 0,000 0,0456567 0,05799965 ! positive regulation of catabolic process GO:0009896 44 32 0,000 0,0456567 0,05796861 ! placenta development GO:0001890 45 32 0,000 0,0456567 0,05793761 ! symbiosis, encompassing mutualism through parasitism GO:0044403 52 32 0,000 0,0456567 0,05790665 ! vesicle localization GO:0051648 50 32 0,000 0,0456567 0,05787571 ! regulation of muscle development GO:0048634 52 33 0,000 0,04705053 0,05961073 ! mRNA export from nucleus GO:0006406 47 33 0,000 0,04705053 0,05957892 ! negative regulation of secretion GO:0051048 53 33 0,000 0,04705053 0,05954715 ! negative regulation of DNA metabolic process GO:0051053 53 33 0,000 0,04705053 0,05951541 ! glial cell differentiation GO:0010001 65 33 0,000 0,04705053 0,0594837 ! cellular component assembly involved in morphogenesis GO:0010927 52 33 0,000 0,04705053 0,05945203 ! sister chromatid segregation GO:0000819 48 33 0,000 0,04705053 0,05942039 ! sphingoid metabolic process GO:0046519 51 33 0,000 0,04705053 0,05938878 ! maintenance of protein location in cell GO:0032507 66 33 0,000 0,04705053 0,05935721 ! spindle organization GO:0007051 39 33 0,000 0,04705053 0,05932567 ! pigment biosynthetic process GO:0046148 55 33 0,000 0,04705053 0,05929416 ! neutral lipid metabolic process GO:0006638 45 33 0,000 0,04705053 0,05926269 GO:0006639|acylglycerol metabolic process, ! erythrocyte differentiation GO:0030218 50 33 0,000 0,04705053 0,05923125 ! protein targeting to membrane GO:0006612 63 33 0,000 0,04705053 0,05919984 ! nucleotide catabolic process GO:0009166 47 33 0,000 0,04705053 0,05916847 ! nuclear-transcribed mRNA catabolic process GO:0000956 47 33 0,000 0,04705053 0,05913713 ! leukocyte chemotaxis GO:0030595 48 33 0,000 0,04705053 0,05910583 GO:0060326|cell chemotaxis, ! BMP signaling pathway GO:0030509 49 33 0,000 0,04705053 0,05907455 ! calcium-mediated signaling GO:0019722 54 33 0,000 0,04705053 0,05904331 ! cytokine production GO:0001816 49 33 0,000 0,04705053 0,05901211 ! regulation of microtubule-based process GO:0032886 66 33 0,000 0,04705053 0,05898093 ! RNA modification GO:0009451 43 33 0,000 0,04705053 0,05894979 ! regulation of B cell activation GO:0050864 55 33 0,000 0,04705053 0,05891868 ! positive regulation of immune effector process GO:0002699 53 33 0,000 0,04705053 0,05888761 ! negative regulation of adenylate cyclase activity GO:0007194 56 34 0,000 0,0484424 0,06059768 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! ER to Golgi vesicle-mediated transport GO:0006888 57 34 0,000 0,0484424 0,06056576 ! xenobiotic metabolic process GO:0006805 49 34 0,000 0,0484424 0,06053386 ! actomyosin structure organization GO:0031032 48 34 0,000 0,0484424 0,060502 ! embryonic skeletal system morphogenesis GO:0048704 49 34 0,000 0,0484424 0,06047018 ! monovalent inorganic cation homeostasis GO:0055067 49 34 0,000 0,0484424 0,06043838 ! negative regulation of DNA binding GO:0043392 54 34 0,000 0,0484424 0,06040662 ! positive regulation of cell development GO:0010720 58 34 0,000 0,0484424 0,0603749 ! response to mechanical stimulus GO:0009612 46 34 0,000 0,0484424 0,06034321 ! cell fate specification GO:0001708 49 34 0,000 0,0484424 0,06031155 ! regulation of Wnt receptor signaling pathway GO:0030111 57 34 0,000 0,0484424 0,06027992 ! peripheral nervous system development GO:0007422 58 34 0,000 0,0484424 0,06024833 ! isoprenoid metabolic process GO:0006720 47 34 0,000 0,0484424 0,06021677 ! adult locomotory behavior GO:0008344 54 34 0,000 0,0484424 0,06018524 ! monosaccharide biosynthetic process GO:0046364 40 34 0,000 0,0484424 0,06015375 ! phosphoinositide biosynthetic process GO:0046489 54 35 0,000 0,0498323 0,06184731 ! collagen metabolic process GO:0032963 47 35 0,000 0,0498323 0,06181498 ! cell junction organization GO:0034330 72 35 0,000 0,0498323 0,06178268 ! regulation of ARF protein signal transduction GO:0032012 56 35 0,000 0,0498323 0,06175042 ! metanephros development GO:0001656 61 35 0,000 0,0498323 0,06171819 ! positive regulation of gene-specific transcription GO:0043193 53 35 0,000 0,0498323 0,06168599 ! female gonad development GO:0008585 55 35 0,000 0,0498323 0,06165383 ! lipid homeostasis GO:0055088 63 35 0,000 0,0498323 0,0616217 ! DNA integrity checkpoint GO:0031570 61 35 0,000 0,0498323 0,06158961 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,0498323 0,06155755 ! negative regulation of hydrolase activity GO:0051346 56 35 0,000 0,0498323 0,06152552 ! hindbrain development GO:0030902 56 35 0,000 0,0498323 0,06149353 ! Rho protein signal transduction GO:0007266 53 35 0,000 0,0498323 0,06146157 ! positive regulation of lymphocyte differentiation GO:0045621 51 35 0,000 0,0498323 0,06142964 ! hormone biosynthetic process GO:0042446 49 35 0,000 0,0498323 0,06139774 ! cytokinesis GO:0000910 57 35 0,000 0,0498323 0,06136588 ! embryonic organ development GO:0048568 53 35 0,000 0,0498323 0,06133405 ! pyrimidine nucleotide metabolic process GO:0006220 48 35 0,000 0,0498323 0,06130226 ! negative regulation of cell activation GO:0050866 58 35 0,000 0,0498323 0,06127049 ! protein homooligomerization GO:0051260 59 35 0,000 0,0498323 0,06123876 ! meiosis I GO:0007127 61 36 0,000 0,05122025 0,06291182 ! negative regulation of cell adhesion GO:0007162 78 36 0,000 0,05122025 0,06287928 ! regulation of metal ion transport GO:0010959 50 36 0,000 0,05122025 0,06284677 ! regulation of intracellular protein transport GO:0033157 64 36 0,000 0,05122025 0,06281429 ! development of primary male sexual characteristics GO:0046546 52 36 0,000 0,05122025 0,06278184 ! spliceosome assembly GO:0000245 65 36 0,000 0,05122025 0,06274943 ! mismatch repair GO:0006298 42 36 0,000 0,05122025 0,06271705 ! regulation of action potential in neuron GO:0019228 60 36 0,000 0,05122025 0,06268471 ! glycerol ether metabolic process GO:0006662 49 36 0,000 0,05122025 0,06265239 ! regulation of proteolysis GO:0030162 53 36 0,000 0,05122025 0,06262012 ! energy coupled proton transport, down electrochemical gradient GO:0015985 55 36 0,000 0,05122025 0,06258787 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 53 36 0,000 0,05122025 0,06255566 ! dorsal/ventral pattern formation GO:0009953 50 36 0,000 0,05122025 0,06252348 ! eye morphogenesis GO:0048592 64 36 0,000 0,05122025 0,06249133 ! cellular response to insulin stimulus GO:0032869 60 36 0,000 0,05122025 0,06245922 ! regulation of smooth muscle cell proliferation GO:0048660 60 37 0,000 0,05260623 0,06411638 ! positive regulation of DNA metabolic process GO:0051054 64 37 0,000 0,05260623 0,06408347 ! mammary gland development GO:0030879 73 37 0,000 0,05260623 0,06405059 ! ear morphogenesis GO:0042471 50 37 0,000 0,05260623 0,06401774 ! odontogenesis GO:0042476 60 37 0,000 0,05260623 0,06398493 ! negative regulation of binding GO:0051100 59 37 0,000 0,05260623 0,06395215 ! mitotic cell cycle checkpoint GO:0007093 74 37 0,000 0,05260623 0,0639194 ! tissue remodeling GO:0048771 65 37 0,000 0,05260623 0,06388669 ! carbohydrate homeostasis GO:0033500 45 37 0,000 0,05260623 0,06385401 GO:0042593|glucose homeostasis, ! keratinocyte differentiation GO:0030216 55 37 0,000 0,05260623 0,06382137 ! natural killer cell activation GO:0030101 45 37 0,000 0,05260623 0,06378875 ! polyol metabolic process GO:0019751 47 37 0,000 0,05260623 0,06375617 ! androgen receptor signaling pathway GO:0030521 66 37 0,000 0,05260623 0,06372363 ! glucan metabolic process GO:0044042 54 37 0,000 0,05260623 0,06369112 GO:0006073|cellular glucan metabolic process, ! positive regulation of transcription factor activity GO:0051091 57 38 0,000 0,05399026 0,06533345 GO:0090047|positive regulation of transcription regulator activity, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 48 38 0,000 0,05399026 0,06530015 GO:0006956|complement activation, ! regulation of hormone secretion GO:0046883 54 38 0,000 0,05399026 0,06526689 ! regulation of neuron projection development GO:0010975 73 38 0,000 0,05399026 0,06523366 ! feeding behavior GO:0007631 50 38 0,000 0,05399026 0,06520046 ! organic ether metabolic process GO:0018904 51 38 0,000 0,05399026 0,06516729 ! antigen processing and presentation of peptide antigen GO:0048002 67 38 0,000 0,05399026 0,06513416 ! development of primary female sexual characteristics GO:0046545 59 38 0,000 0,05399026 0,06510107 GO:0046660|female sex differentiation, ! regulation of Rab protein signal transduction GO:0032483 58 38 0,000 0,05399026 0,065068 GO:0032313|regulation of Rab GTPase activity, ! multicellular organismal macromolecule metabolic process GO:0044259 51 38 0,000 0,05399026 0,06503497 ! ion transmembrane transport GO:0034220 58 38 0,000 0,05399026 0,06500198 ! heterocycle biosynthetic process GO:0018130 49 38 0,000 0,05399026 0,06496902 ! ribonucleoside metabolic process GO:0009119 51 38 0,000 0,05399026 0,06493609 ! neuron migration GO:0001764 59 38 0,000 0,05399026 0,06490319 ! maintenance of protein location GO:0045185 72 38 0,000 0,05399026 0,06487033 ! pigment metabolic process GO:0042440 66 38 0,000 0,05399026 0,0648375 ! regulation of cell morphogenesis involved in differentiation GO:0010769 72 38 0,000 0,05399026 0,0648047 ! mRNA catabolic process GO:0006402 58 39 0,000 0,05537234 0,06643002 ! response to reactive oxygen species GO:0000302 64 39 0,000 0,05537234 0,06639645 ! establishment or maintenance of cell polarity GO:0007163 74 39 0,000 0,05537234 0,06636292 ! striated muscle cell differentiation GO:0051146 58 39 0,000 0,05537234 0,06632942 ! neural tube development GO:0021915 58 39 0,000 0,05537234 0,06629595 ! polysaccharide biosynthetic process GO:0000271 51 39 0,000 0,05537234 0,06626252 ! regulation of protein stability GO:0031647 58 39 0,000 0,05537234 0,06622912 ! female gamete generation GO:0007292 50 39 0,000 0,05537234 0,06619576 ! aerobic respiration GO:0009060 56 39 0,000 0,05537234 0,06616242 ! positive regulation of leukocyte proliferation GO:0070665 64 39 0,000 0,05537234 0,06612913 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! response to xenobiotic stimulus GO:0009410 55 39 0,000 0,05537234 0,06609586 ! protein amino acid N-linked glycosylation GO:0006487 57 40 0,000 0,05675247 0,06770921 ! Notch signaling pathway GO:0007219 64 40 0,000 0,05675247 0,06767519 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 68 40 0,000 0,05675247 0,0676412 ! monocarboxylic acid transport GO:0015718 68 40 0,000 0,05675247 0,06760724 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 71 40 0,000 0,05675247 0,06757332 ! hormone-mediated signaling GO:0009755 57 40 0,000 0,05675247 0,06753943 ! alcohol biosynthetic process GO:0046165 48 40 0,000 0,05675247 0,06750558 ! phagocytosis GO:0006909 65 40 0,000 0,05675247 0,06747175 ! mesenchymal cell development GO:0014031 70 40 0,000 0,05675247 0,06743797 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! erythrocyte homeostasis GO:0034101 60 40 0,000 0,05675247 0,06740422 ! pigmentation GO:0043473 81 40 0,000 0,05675247 0,0673705 ! developmental growth GO:0048589 70 40 0,000 0,05675247 0,06733681 ! synapse organization GO:0050808 61 40 0,000 0,05675247 0,06730316 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 72 41 0,000 0,05813066 0,06890312 ! detection of stimulus involved in sensory perception GO:0050906 55 41 0,000 0,05813066 0,06886872 ! regulation of epithelial cell proliferation GO:0050678 80 41 0,000 0,05813066 0,06883436 ! ATP synthesis coupled electron transport GO:0042773 50 41 0,000 0,05813066 0,06880003 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of protein secretion GO:0050708 55 41 0,000 0,05813066 0,06876573 ! cell growth GO:0016049 71 41 0,000 0,05813066 0,06873147 ! maintenance of location in cell GO:0051651 77 41 0,000 0,05813066 0,06869724 ! transforming growth factor beta receptor signaling pathway GO:0007179 59 42 0,000 0,0595069 0,07028863 ! regulation of nucleocytoplasmic transport GO:0046822 75 42 0,000 0,0595069 0,07025366 ! learning GO:0007612 75 42 0,000 0,0595069 0,07021873 ! negative regulation of protein complex disassembly GO:0043242 78 42 0,000 0,0595069 0,07018383 ! cellular amide metabolic process GO:0043603 63 42 0,000 0,0595069 0,07014896 ! morphogenesis of embryonic epithelium GO:0016331 69 42 0,000 0,0595069 0,07011413 ! gliogenesis GO:0042063 85 42 0,000 0,0595069 0,07007934 ! endosome transport GO:0016197 74 42 0,000 0,0595069 0,07004458 ! induction of apoptosis by intracellular signals GO:0008629 78 42 0,000 0,0595069 0,07000985 ! male sex differentiation GO:0046661 62 42 0,000 0,0595069 0,06997516 ! double-strand break repair GO:0006302 75 42 0,000 0,0595069 0,0699405 ! epidermal cell differentiation GO:0009913 61 42 0,000 0,0595069 0,06990587 ! regulation of myeloid cell differentiation GO:0045637 78 42 0,000 0,0595069 0,06987128 ! oxidoreduction coenzyme metabolic process GO:0006733 62 42 0,000 0,0595069 0,06983673 ! mitochondrial transport GO:0006839 66 43 0,000 0,06088119 0,07141427 ! protein amino acid lipidation GO:0006497 69 43 0,000 0,06088119 0,07137899 ! energy reserve metabolic process GO:0006112 67 43 0,000 0,06088119 0,07134374 ! response to calcium ion GO:0051592 65 43 0,000 0,06088119 0,07130853 ! regulation of tube size GO:0035150 69 43 0,000 0,06088119 0,07127335 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 78 43 0,000 0,06088119 0,0712382 ! regulation of T cell proliferation GO:0042129 72 43 0,000 0,06088119 0,07120309 ! positive regulation of DNA binding GO:0043388 65 43 0,000 0,06088119 0,07116802 ! T cell differentiation GO:0030217 78 43 0,000 0,06088119 0,07113298 ! icosanoid metabolic process GO:0006690 65 43 0,000 0,06088119 0,07109797 ! amino acid activation GO:0043038 61 43 0,000 0,06088119 0,071063 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of protein transport GO:0051222 59 43 0,000 0,06088119 0,07102806 ! G1/S transition of mitotic cell cycle GO:0000082 93 44 0,000 0,06225355 0,07259345 ! epithelial cell differentiation GO:0030855 64 44 0,000 0,06225355 0,0725578 ! receptor-mediated endocytosis GO:0006898 85 44 0,000 0,06225355 0,07252218 ! cytoskeleton-dependent intracellular transport GO:0030705 78 44 0,000 0,06225355 0,07248659 ! peptide metabolic process GO:0006518 64 44 0,000 0,06225355 0,07245104 ! multicellular organismal metabolic process GO:0044236 57 44 0,000 0,06225355 0,07241553 ! inner ear development GO:0048839 66 44 0,000 0,06225355 0,07238005 ! regulation of lymphocyte mediated immunity GO:0002706 77 44 0,000 0,06225355 0,0723446 ! regulation of gene expression, epigenetic GO:0040029 86 44 0,000 0,06225355 0,07230919 ! chromatin remodeling GO:0006338 73 44 0,000 0,06225355 0,07227382 ! biopolymer methylation GO:0043414 67 44 0,000 0,06225355 0,07223847 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 58 44 0,000 0,06225355 0,07220317 ! JNK cascade GO:0007254 66 44 0,000 0,06225355 0,07216789 ! regulation of cell shape GO:0008360 83 44 0,000 0,06225355 0,07213266 ! activation of adenylate cyclase activity GO:0007190 79 45 0,000 0,06362397 0,07368457 ! positive regulation of binding GO:0051099 67 45 0,000 0,06362397 0,07364863 ! positive regulation of cell cycle GO:0045787 83 45 0,000 0,06362397 0,07361272 ! stress-activated protein kinase signaling pathway GO:0031098 69 45 0,000 0,06362397 0,07357685 ! regulation of ion transport GO:0043269 60 45 0,000 0,06362397 0,07354101 ! glucose transport GO:0015758 60 45 0,000 0,06362397 0,0735052 ! neuromuscular process GO:0050905 89 45 0,000 0,06362397 0,07346943 ! positive regulation of cytokine biosynthetic process GO:0042108 61 45 0,000 0,06362397 0,0734337 ! glycosaminoglycan metabolic process GO:0030203 68 45 0,000 0,06362397 0,073398 ! regulation of T cell differentiation GO:0045580 68 45 0,000 0,06362397 0,07336234 ! regulation of actin filament polymerization GO:0030833 71 46 0,000 0,06499246 0,07490389 ! regulation of action potential GO:0001508 80 46 0,000 0,06499246 0,07486753 ! hexose transport GO:0008645 62 46 0,000 0,06499246 0,0748312 GO:0015749|monosaccharide transport, ! excretion GO:0007588 72 46 0,000 0,06499246 0,07479491 ! regulation of leukocyte mediated immunity GO:0002703 80 46 0,000 0,06499246 0,07475866 ! regulation of inflammatory response GO:0050727 74 46 0,000 0,06499246 0,07472244 ! epithelial tube morphogenesis GO:0060562 73 46 0,000 0,06499246 0,07468625 ! positive regulation of defense response GO:0031349 70 47 0,000 0,06635902 0,07621972 ! branching morphogenesis of a tube GO:0048754 85 47 0,000 0,06635902 0,07618285 ! embryonic skeletal system development GO:0048706 65 47 0,000 0,06635902 0,07614601 ! unsaturated fatty acid metabolic process GO:0033559 71 47 0,000 0,06635902 0,07610921 ! lipoprotein biosynthetic process GO:0042158 74 47 0,000 0,06635902 0,07607244 ! regulation of JNK cascade GO:0046328 72 47 0,000 0,06635902 0,07603571 ! response to UV GO:0009411 79 47 0,000 0,06635902 0,07599901 ! positive regulation of adenylate cyclase activity GO:0045762 90 48 0,000 0,06772365 0,07752446 ! viral infectious cycle GO:0019058 80 48 0,000 0,06772365 0,07748708 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 75 48 0,000 0,06772365 0,07744974 ! leukocyte migration GO:0050900 76 48 0,000 0,06772365 0,07741243 ! cellular amino acid biosynthetic process GO:0008652 60 48 0,000 0,06772365 0,07737516 ! striated muscle contraction GO:0006941 78 48 0,000 0,06772365 0,07733793 ! vascular process in circulatory system GO:0003018 78 48 0,000 0,06772365 0,07730073 ! DNA-dependent DNA replication GO:0006261 73 48 0,000 0,06772365 0,07726356 ! tRNA processing GO:0008033 56 48 0,000 0,06772365 0,07722644 ! cell maturation GO:0048469 69 48 0,000 0,06772365 0,07718934 ! detection of abiotic stimulus GO:0009582 66 48 0,000 0,06772365 0,07715229 ! vesicle organization GO:0016050 87 48 0,000 0,06772365 0,07711526 ! respiratory electron transport chain GO:0022904 63 49 0,000 0,06908635 0,07862921 ! regulation of cell projection organization GO:0031344 95 49 0,000 0,06908635 0,07859152 ! glycolysis GO:0006096 63 49 0,000 0,06908635 0,07855386 ! regulation of gene-specific transcription GO:0032583 78 49 0,000 0,06908635 0,07851624 ! regulation of protein complex disassembly GO:0043244 88 49 0,000 0,06908635 0,07847865 ! induction of apoptosis by extracellular signals GO:0008624 96 49 0,000 0,06908635 0,0784411 ! endocrine system development GO:0035270 86 49 0,000 0,06908635 0,07840359 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,06908635 0,07836611 ! generation of a signal involved in cell-cell signaling GO:0003001 74 49 0,000 0,06908635 0,07832867 ! gastrulation GO:0007369 80 49 0,000 0,06908635 0,07829126 ! RNA elongation from RNA polymerase II promoter GO:0006368 65 49 0,000 0,06908635 0,07825389 ! positive regulation of cyclase activity GO:0031281 91 49 0,000 0,06908635 0,07821656 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 84 49 0,000 0,06908635 0,07817926 ! regulation of intracellular transport GO:0032386 83 49 0,000 0,06908635 0,07814199 ! methylation GO:0032259 74 49 0,000 0,06908635 0,07810477 ! cell redox homeostasis GO:0045454 72 50 0,000 0,07044713 0,07960525 ! negative regulation of cell migration GO:0030336 105 50 0,000 0,07044713 0,07956736 ! regulation of muscle contraction GO:0006937 75 50 0,000 0,07044713 0,07952951 ! cellular polysaccharide metabolic process GO:0044264 70 50 0,000 0,07044713 0,07949169 ! histone modification GO:0016570 81 50 0,000 0,07044713 0,07945391 ! positive regulation of lyase activity GO:0051349 92 50 0,000 0,07044713 0,07941617 ! heterocycle catabolic process GO:0046700 74 50 0,000 0,07044713 0,07937846 ! regulation of mast cell proliferation GO:0070666 80 50 0,000 0,07044713 0,07934078 ! RNA catabolic process GO:0006401 77 51 0,000 0,07180599 0,08083283 ! chloride transport GO:0006821 78 51 0,000 0,07180599 0,0807945 ! membrane fusion GO:0006944 82 51 0,000 0,07180599 0,08075621 ! regulation of ossification GO:0030278 82 51 0,000 0,07180599 0,08071796 ! heart morphogenesis GO:0003007 71 51 0,000 0,07180599 0,08067974 ! RNA elongation GO:0006354 67 51 0,000 0,07180599 0,08064155 ! aminoglycan metabolic process GO:0006022 77 52 0,000 0,07316293 0,0821266 ! activation of phospholipase C activity GO:0007202 93 52 0,000 0,07316293 0,08208777 GO:0010863|positive regulation of phospholipase C activity, ! skeletal muscle fiber development GO:0048741 79 52 0,000 0,07316293 0,08204897 ! regulation of DNA replication GO:0006275 88 52 0,000 0,07316293 0,08201021 ! immunoglobulin mediated immune response GO:0016064 72 52 0,000 0,07316293 0,08197149 GO:0019724|B cell mediated immunity, ! cell recognition GO:0008037 78 52 0,000 0,07316293 0,08193281 ! covalent chromatin modification GO:0016569 90 52 0,000 0,07316293 0,08189416 ! regulation of adaptive immune response GO:0002819 90 52 0,000 0,07316293 0,08185555 ! proton transport GO:0015992 78 52 0,000 0,07316293 0,08181698 ! negative regulation of immune system process GO:0002683 90 52 0,000 0,07316293 0,08177844 ! protein amino acid autophosphorylation GO:0046777 97 52 0,000 0,07316293 0,08173994 ! transition metal ion transport GO:0000041 88 53 0,000 0,07451795 0,08321463 ! regulation of cyclin-dependent protein kinase activity GO:0000079 86 53 0,000 0,07451795 0,08317549 ! regulation of angiogenesis GO:0045765 105 53 0,000 0,07451795 0,08313639 ! muscle fiber development GO:0048747 80 53 0,000 0,07451795 0,08309732 ! sulfur compound biosynthetic process GO:0044272 71 53 0,000 0,07451795 0,08305829 ! positive regulation of phospholipase activity GO:0010518 94 53 0,000 0,07451795 0,0830193 ! cytokine-mediated signaling pathway GO:0019221 77 53 0,000 0,07451795 0,08298034 ! regulation of multicellular organism growth GO:0040014 72 53 0,000 0,07451795 0,08294142 ! regulation of endocytosis GO:0030100 71 53 0,000 0,07451795 0,08290253 ! regulation of lymphocyte differentiation GO:0045619 84 53 0,000 0,07451795 0,08286368 ! glutamine family amino acid metabolic process GO:0009064 71 53 0,000 0,07451795 0,08282487 ! cellular amino acid derivative biosynthetic process GO:0042398 73 53 0,000 0,07451795 0,08278609 ! regulation of leukocyte proliferation GO:0070663 88 53 0,000 0,07451795 0,08274736 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! maintenance of location GO:0051235 94 53 0,000 0,07451795 0,08270865 ! hydrogen transport GO:0006818 81 54 0,000 0,07587106 0,08417112 ! response to estrogen stimulus GO:0043627 88 54 0,000 0,07587106 0,08413179 ! regulation of mitosis GO:0007088 91 54 0,000 0,07587106 0,0840925 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 100 54 0,000 0,07587106 0,08405324 ! negative regulation of cytoskeleton organization GO:0051494 96 54 0,000 0,07587106 0,08401401 ! regulation of actin polymerization or depolymerization GO:0008064 81 54 0,000 0,07587106 0,08397483 ! nucleotide-excision repair GO:0006289 70 54 0,000 0,07587106 0,08393568 ! sphingolipid metabolic process GO:0006665 80 54 0,000 0,07587106 0,08389657 ! ribonucleoprotein complex assembly GO:0022618 90 54 0,000 0,07587106 0,08385749 ! morphogenesis of a branching structure GO:0001763 99 54 0,000 0,07587106 0,08381845 ! germ cell development GO:0007281 82 54 0,000 0,07587106 0,08377945 ! positive regulation of cytokine production GO:0001819 83 54 0,000 0,07587106 0,08374048 ! regulation of protein polymerization GO:0032271 84 54 0,000 0,07587106 0,08370155 ! establishment of organelle localization GO:0051656 91 54 0,000 0,07587106 0,08366265 ! glycerophospholipid biosynthetic process GO:0046474 82 55 0,000 0,07722227 0,08511307 ! ear development GO:0043583 83 55 0,000 0,07722227 0,08507355 ! regulation of phospholipase activity GO:0010517 96 55 0,000 0,07722227 0,08503408 ! regulation of protein catabolic process GO:0042176 83 55 0,000 0,07722227 0,08499464 ! integrin-mediated signaling pathway GO:0007229 93 55 0,000 0,07722227 0,08495523 ! positive regulation of lipase activity GO:0060193 96 55 0,000 0,07722227 0,08491586 ! regulation of actin filament length GO:0030832 88 56 0,000 0,07857156 0,08635957 ! positive regulation of secretion GO:0051047 83 56 0,000 0,07857156 0,08631959 ! nucleoside metabolic process GO:0009116 74 56 0,000 0,07857156 0,08627964 ! positive regulation of organelle organization GO:0010638 95 56 0,000 0,07857156 0,08623974 ! adult behavior GO:0030534 90 56 0,000 0,07857156 0,08619987 ! cartilage development GO:0051216 84 56 0,000 0,07857156 0,08616003 ! aging GO:0007568 91 57 0,000 0,07991895 0,08759707 ! cellular amino acid catabolic process GO:0009063 82 57 0,000 0,07991895 0,08755663 ! single fertilization GO:0007338 67 57 0,000 0,07991895 0,08751623 ! regulation of cellular component size GO:0032535 90 58 0,000 0,08126444 0,08894857 ! lipid modification GO:0030258 82 58 0,000 0,08126444 0,08890756 ! positive regulation of growth GO:0045927 78 58 0,000 0,08126444 0,08886659 ! DNA damage response, signal transduction GO:0042770 105 58 0,000 0,08126444 0,08882566 ! membrane lipid metabolic process GO:0006643 88 58 0,000 0,08126444 0,08878476 ! negative regulation of cell motion GO:0051271 118 58 0,000 0,08126444 0,08874391 ! regulation of bone remodeling GO:0046850 102 59 0,000 0,08260802 0,09016966 ! viral reproductive process GO:0022415 99 59 0,000 0,08260802 0,0901282 ! skeletal system morphogenesis GO:0048705 90 59 0,000 0,08260802 0,09008678 ! chromosome segregation GO:0007059 93 59 0,000 0,08260802 0,0900454 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,08260802 0,09000406 ! negative regulation of response to stimulus GO:0048585 88 59 0,000 0,08260802 0,08996275 ! cell projection assembly GO:0030031 90 59 0,000 0,08260802 0,08992149 ! glucose catabolic process GO:0006007 78 60 0,000 0,08394971 0,09134006 ! regulation of lipid metabolic process GO:0019216 93 60 0,000 0,08394971 0,0912982 ! water-soluble vitamin metabolic process GO:0006767 84 60 0,000 0,08394971 0,09125638 ! kidney development GO:0001822 101 60 0,000 0,08394971 0,09121459 ! positive regulation of cell motion GO:0051272 110 60 0,000 0,08394971 0,09117285 ! regulation of protein complex assembly GO:0043254 95 61 0,000 0,08528951 0,09258555 ! carbohydrate transport GO:0008643 83 61 0,000 0,08528951 0,09254321 ! protein maturation by peptide bond cleavage GO:0051605 86 61 0,000 0,08528951 0,09250092 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 98 62 0,000 0,08662741 0,09390902 ! negative regulation of protein kinase activity GO:0006469 110 62 0,000 0,08662741 0,09386614 ! activation of MAPK activity GO:0000187 95 62 0,000 0,08662741 0,0938233 ! multicellular organism reproduction GO:0032504 98 62 0,000 0,08662741 0,0937805 GO:0048609|reproductive process in a multicellular organism, ! lipoprotein metabolic process GO:0042157 96 62 0,000 0,08662741 0,09373773 ! glycerolipid biosynthetic process GO:0045017 92 62 0,000 0,08662741 0,09369501 ! detection of external stimulus GO:0009581 78 62 0,000 0,08662741 0,09365232 ! regulation of tissue remodeling GO:0034103 113 62 0,000 0,08662741 0,09360967 ! secondary metabolic process GO:0019748 95 62 0,000 0,08662741 0,09356707 ! gonad development GO:0008406 91 62 0,000 0,08662741 0,0935245 ! exocytosis GO:0006887 91 63 0,000 0,08796342 0,0949237 ! negative regulation of kinase activity GO:0033673 112 63 0,000 0,08796342 0,09488055 ! oxygen and reactive oxygen species metabolic process GO:0006800 89 63 0,000 0,08796342 0,09483744 ! embryonic limb morphogenesis GO:0030326 96 63 0,000 0,08796342 0,09479437 GO:0035113|embryonic appendage morphogenesis, ! coenzyme biosynthetic process GO:0009108 81 63 0,000 0,08796342 0,09475134 ! regulation of heart contraction GO:0008016 104 63 0,000 0,08796342 0,09470835 ! developmental maturation GO:0021700 90 63 0,000 0,08796342 0,0946654 ! actin filament organization GO:0007015 107 64 0,000 0,08929755 0,09605761 ! fertilization GO:0009566 79 64 0,000 0,08929755 0,09601409 ! viral reproduction GO:0016032 104 64 0,000 0,08929755 0,0959706 ! myeloid cell differentiation GO:0030099 101 64 0,000 0,08929755 0,09592716 ! amine catabolic process GO:0009310 100 65 0,000 0,09062979 0,09731425 ! negative regulation of cell growth GO:0030308 123 65 0,000 0,09062979 0,09727024 ! camera-type eye development GO:0043010 103 65 0,000 0,09062979 0,09722627 ! steroid hormone receptor signaling pathway GO:0030518 116 65 0,000 0,09062979 0,09718233 ! regulation of lipase activity GO:0060191 117 65 0,000 0,09062979 0,09713844 ! regulation of homeostatic process GO:0032844 122 65 0,000 0,09062979 0,09709458 ! organelle localization GO:0051640 105 65 0,000 0,09062979 0,09705077 ! regulation of transcription factor activity GO:0051090 109 66 0,000 0,09196015 0,09843096 GO:0090046|regulation of transcription regulator activity, ! cellular hormone metabolic process GO:0034754 95 66 0,000 0,09196015 0,09838658 ! sensory perception of smell GO:0007608 81 66 0,000 0,09196015 0,09834225 ! regulation of cytokine biosynthetic process GO:0042035 91 66 0,000 0,09196015 0,09829795 ! cAMP-mediated signaling GO:0019933 109 66 0,000 0,09196015 0,09825369 ! lung development GO:0030324 112 66 0,000 0,09196015 0,09820947 ! lymphocyte mediated immunity GO:0002449 95 66 0,000 0,09196015 0,09816529 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 97 66 0,000 0,09196015 0,09812115 ! negative regulation of transferase activity GO:0051348 117 66 0,000 0,09196015 0,09807705 ! protein oligomerization GO:0051259 109 66 0,000 0,09196015 0,09803299 ! cell cycle checkpoint GO:0000075 123 67 0,000 0,09328864 0,09940455 ! negative regulation of cell size GO:0045792 125 67 0,000 0,09328864 0,09935993 ! regulation of cellular response to stress GO:0080135 100 67 0,000 0,09328864 0,09931536 ! appendage morphogenesis GO:0035107 103 67 0,000 0,09328864 0,09927082 GO:0035108|limb morphogenesis, ! fatty acid biosynthetic process GO:0006633 107 67 0,000 0,09328864 0,09922633 ! extracellular matrix organization GO:0030198 117 67 0,000 0,09328864 0,09918187 ! negative regulation of ligase activity GO:0051352 100 67 0,000 0,09328864 0,09913745 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! meiosis GO:0007126 110 68 0,000 0,09461524 0,10050222 GO:0051327|M phase of meiotic cell cycle, ! phosphoinositide metabolic process GO:0030384 100 68 0,000 0,09461524 0,10045725 ! defense response to bacterium GO:0042742 79 68 0,000 0,09461524 0,10041233 ! regulation of vesicle-mediated transport GO:0060627 98 68 0,000 0,09461524 0,10036744 ! activation of immune response GO:0002253 93 68 0,000 0,09461524 0,10032259 ! appendage development GO:0048736 108 69 0,000 0,09593997 0,1016818 GO:0060173|limb development, ! respiratory tube development GO:0030323 117 69 0,000 0,09593997 0,10163641 ! urogenital system development GO:0001655 114 69 0,000 0,09593997 0,10159105 ! meiotic cell cycle GO:0051321 111 69 0,000 0,09593997 0,10154574 ! hexose catabolic process GO:0019320 95 70 0,000 0,09726283 0,1029 ! adaptive immune response GO:0002250 102 70 0,000 0,09726283 0,10285414 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 104 71 0,000 0,09858382 0,10420463 ! elevation of cytosolic calcium ion concentration GO:0007204 126 71 0,000 0,09858382 0,10415824 ! axon guidance GO:0007411 116 71 0,000 0,09858382 0,10411188 ! intracellular receptor-mediated signaling pathway GO:0030522 124 71 0,000 0,09858382 0,10406557 ! response to drug GO:0042493 115 72 0,000 0,09990294 0,10541115 ! cytosolic calcium ion homeostasis GO:0051480 128 72 0,000 0,09990294 0,1053643 ! homeostasis of number of cells GO:0048872 109 72 0,000 0,09990294 0,1053175 ! positive regulation of T cell activation GO:0050870 117 72 0,000 0,09990294 0,10527073 ! respiratory system development GO:0060541 123 72 0,000 0,09990294 0,105224 ! rhythmic process GO:0048511 113 72 0,000 0,09990294 0,10517732 ! regulation of immune effector process GO:0002697 121 72 0,000 0,09990294 0,10513068 ! learning or memory GO:0007611 132 73 0,000 0,1012202 0,10646965 ! humoral immune response GO:0006959 93 73 0,000 0,1012202 0,10642248 ! regulation of MAPKKK cascade GO:0043408 123 73 0,000 0,1012202 0,10637535 ! acute inflammatory response GO:0002526 107 74 0,000 0,1025356 0,10771004 ! activation of protein kinase activity GO:0032147 115 74 0,000 0,1025356 0,10766238 ! development of primary sexual characteristics GO:0045137 107 74 0,000 0,1025356 0,10761476 ! transcription initiation from RNA polymerase II promoter GO:0006367 100 74 0,000 0,1025356 0,10756719 ! regulation of neuron differentiation GO:0045664 130 74 0,000 0,1025356 0,10751966 ! regulation of synaptic transmission GO:0050804 117 74 0,000 0,1025356 0,10747216 ! leukocyte mediated immunity GO:0002443 107 75 0,000 0,10384914 0,10880089 ! inorganic anion transport GO:0015698 109 75 0,000 0,10384914 0,10875287 ! regulation of catabolic process GO:0009894 114 75 0,000 0,10384914 0,1087049 ! response to metal ion GO:0010038 114 76 0,000 0,10516082 0,11002938 ! phospholipid biosynthetic process GO:0008654 109 76 0,000 0,10516082 0,10998089 ! phosphoinositide-mediated signaling GO:0048015 122 76 0,000 0,10516082 0,10993244 ! negative regulation of transport GO:0051051 122 77 0,000 0,10647065 0,11125269 ! cellular lipid catabolic process GO:0044242 117 77 0,000 0,10647065 0,11120372 ! response to nutrient GO:0007584 114 77 0,000 0,10647065 0,1111548 ! monosaccharide catabolic process GO:0046365 104 77 0,000 0,10647065 0,11110592 ! regulation of blood pressure GO:0008217 119 78 0,000 0,10777863 0,1124214 ! muscle cell differentiation GO:0042692 117 78 0,000 0,10777863 0,11237201 ! negative regulation of growth GO:0045926 140 78 0,000 0,10777863 0,11232266 ! antigen processing and presentation GO:0019882 114 78 0,000 0,10777863 0,11227335 ! steroid biosynthetic process GO:0006694 111 79 0,000 0,10908476 0,11358409 ! regulation of adenylate cyclase activity GO:0045761 143 80 0,000 0,11038904 0,11489175 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 123 80 0,000 0,11038904 0,11484138 ! regulation of DNA binding GO:0051101 130 80 0,000 0,11038904 0,11479106 ! tube morphogenesis GO:0035239 140 80 0,000 0,11038904 0,11474078 ! eye development GO:0001654 130 80 0,000 0,11038904 0,11469054 ! intracellular protein transmembrane transport GO:0065002 115 80 0,000 0,11038904 0,11464035 ! protein ubiquitination GO:0016567 135 80 0,000 0,11038904 0,1145902 ! negative regulation of organelle organization GO:0010639 136 80 0,000 0,11038904 0,11454009 ! regulation of transmission of nerve impulse GO:0051969 126 80 0,000 0,11038904 0,11449003 ! response to steroid hormone stimulus GO:0048545 129 80 0,000 0,11038904 0,11444002 ! cellular response to hormone stimulus GO:0032870 125 80 0,000 0,11038904 0,11439004 ! blood coagulation GO:0007596 129 81 0,000 0,11169148 0,11568917 GO:0050817|coagulation, ! amine biosynthetic process GO:0009309 108 81 0,000 0,11169148 0,11563869 ! response to inorganic substance GO:0010035 127 81 0,000 0,11169148 0,11558826 ! oxidative phosphorylation GO:0006119 110 81 0,000 0,11169148 0,11553787 ! nitrogen compound catabolic process GO:0044270 125 81 0,000 0,11169148 0,11548753 ! response to hypoxia GO:0001666 155 81 0,000 0,11169148 0,11543723 ! regulation of protein transport GO:0051223 123 81 0,000 0,11169148 0,11538698 GO:0070201|regulation of establishment of protein localization, ! regulation of cAMP biosynthetic process GO:0030817 148 82 0,000 0,11299208 0,11667981 ! neuropeptide signaling pathway GO:0007218 101 82 0,000 0,11299208 0,11662906 ! regulation of cell morphogenesis GO:0022604 155 82 0,000 0,11299208 0,11657835 ! regulation of cyclase activity GO:0031279 146 82 0,000 0,11299208 0,11652769 ! cholesterol metabolic process GO:0008203 120 83 0,000 0,11429084 0,11781588 ! response to oxygen levels GO:0070482 160 83 0,000 0,11429084 0,11776472 ! regulation of cell cycle process GO:0010564 139 83 0,000 0,11429084 0,11771361 ! regulation of lyase activity GO:0051339 147 83 0,000 0,11429084 0,11766254 ! cofactor biosynthetic process GO:0051188 108 83 0,000 0,11429084 0,11761152 ! positive regulation of lymphocyte activation GO:0051251 134 83 0,000 0,11429084 0,11756054 ! regulation of cAMP metabolic process GO:0030814 153 84 0,000 0,11558776 0,11884305 ! digestion GO:0007586 111 84 0,000 0,11558776 0,11879158 ! regulation of neurological system process GO:0031644 133 84 0,000 0,11558776 0,11874016 ! ATP biosynthetic process GO:0006754 131 84 0,000 0,11558776 0,11868878 ! biogenic amine metabolic process GO:0006576 128 85 0,000 0,11688285 0,1199667 ! T cell activation GO:0042110 154 85 0,000 0,11688285 0,11991483 ! sex differentiation GO:0007548 126 85 0,000 0,11688285 0,11986301 ! protein import into nucleus GO:0006606 145 85 0,000 0,11688285 0,11981123 ! one-carbon metabolic process GO:0006730 126 85 0,000 0,11688285 0,1197595 ! alcohol catabolic process GO:0046164 119 86 0,000 0,11817611 0,12103233 ! carbohydrate biosynthetic process GO:0016051 111 86 0,000 0,11817611 0,12098012 ! regulation of nucleotide biosynthetic process GO:0030808 155 87 0,000 0,11946754 0,12224945 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! hemostasis GO:0007599 138 87 0,000 0,11946754 0,12219676 ! regulation of defense response GO:0031347 135 87 0,000 0,11946754 0,12214411 ! Golgi vesicle transport GO:0048193 145 87 0,000 0,11946754 0,1220915 ! tRNA metabolic process GO:0006399 110 87 0,000 0,11946754 0,12203895 ! sensory perception of chemical stimulus GO:0007606 108 87 0,000 0,11946754 0,12198643 ! gland development GO:0048732 170 87 0,000 0,11946754 0,12193397 ! interphase of mitotic cell cycle GO:0051329 166 87 0,000 0,11946754 0,12188154 ! vitamin metabolic process GO:0006766 117 87 0,000 0,11946754 0,12182917 ! forebrain development GO:0030900 151 87 0,000 0,11946754 0,12177684 ! regulation of membrane potential GO:0042391 144 88 0,000 0,12075714 0,12303852 ! ossification GO:0001503 150 89 0,000 0,12204492 0,12429725 GO:0060348|bone development, ! nucleosome assembly GO:0006334 113 89 0,000 0,12204492 0,12424393 GO:0031497|chromatin assembly, ! interphase GO:0051325 169 89 0,000 0,12204492 0,12419065 ! regulation of DNA metabolic process GO:0051052 152 90 0,000 0,12333088 0,12544543 ! microtubule cytoskeleton organization GO:0000226 133 90 0,000 0,12333088 0,12539168 ! regulation of cyclic nucleotide metabolic process GO:0030799 161 90 0,000 0,12333088 0,12533798 ! skeletal muscle tissue development GO:0007519 135 90 0,000 0,12333088 0,12528433 GO:0060538|skeletal muscle organ development, ! transcription initiation GO:0006352 128 90 0,000 0,12333088 0,12523072 ! nuclear import GO:0051170 153 90 0,000 0,12333088 0,12517715 ! regulation of protein localization GO:0032880 141 90 0,000 0,12333088 0,12512364 ! positive regulation of cell activation GO:0050867 146 90 0,000 0,12333088 0,12507016 GO:0002696|positive regulation of leukocyte activation, ! carboxylic acid catabolic process GO:0046395 132 91 0,000 0,12461502 0,12631843 GO:0016054|organic acid catabolic process, ! detection of stimulus GO:0051606 123 91 0,000 0,12461502 0,1262645 ! protein localization in nucleus GO:0034504 161 92 0,000 0,12589735 0,12750935 ! sterol metabolic process GO:0016125 136 92 0,000 0,12589735 0,12745495 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 141 93 0,000 0,12717786 0,1286964 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cell cycle arrest GO:0007050 171 93 0,000 0,12717786 0,12864154 ! protein-DNA complex assembly GO:0065004 119 93 0,000 0,12717786 0,12858673 ! rRNA processing GO:0006364 124 93 0,000 0,12717786 0,12853196 ! positive regulation of MAP kinase activity GO:0043406 143 93 0,000 0,12717786 0,12847725 ! regulation of nucleotide metabolic process GO:0006140 164 93 0,000 0,12717786 0,12842258 ! anterior/posterior pattern formation GO:0009952 141 93 0,000 0,12717786 0,12836795 ! negative regulation of multicellular organismal process GO:0051241 150 93 0,000 0,12717786 0,12831337 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 140 94 0,000 0,12845655 0,12954841 ! ribonucleoside triphosphate biosynthetic process GO:0009201 142 94 0,000 0,12845655 0,12949338 ! rRNA metabolic process GO:0016072 125 94 0,000 0,12845655 0,12943839 ! hormone metabolic process GO:0042445 135 94 0,000 0,12845655 0,12938345 ! protein processing GO:0016485 127 94 0,000 0,12845655 0,12932856 ! nucleoside triphosphate biosynthetic process GO:0009142 143 95 0,000 0,12973344 0,13055872 ! anatomical structure homeostasis GO:0060249 152 95 0,000 0,12973344 0,13050338 ! ATP metabolic process GO:0046034 150 96 0,000 0,13100853 0,13173019 ! nucleosome organization GO:0034728 126 96 0,000 0,13100853 0,13167439 ! protein modification by small protein conjugation GO:0032446 153 96 0,000 0,13100853 0,13161864 ! female pregnancy GO:0007565 148 96 0,000 0,13100853 0,13156294 ! regulation of neurogenesis GO:0050767 179 97 0,000 0,13228181 0,13278542 ! reproductive developmental process GO:0003006 149 97 0,000 0,13228181 0,13272927 ! response to virus GO:0009615 141 98 0,000 0,13355329 0,13394841 ! polysaccharide metabolic process GO:0005976 141 98 0,000 0,13355329 0,13389182 ! Wnt receptor signaling pathway GO:0016055 161 98 0,000 0,13355329 0,13383528 ! regulation of T cell activation GO:0050863 155 98 0,000 0,13355329 0,13377879 ! glycerophospholipid metabolic process GO:0006650 143 99 0,000 0,13482297 0,13499363 ! positive regulation of immune response GO:0050778 143 99 0,000 0,13482297 0,13493669 ! sulfur metabolic process GO:0006790 136 99 0,000 0,13482297 0,13487981 ! carbohydrate catabolic process GO:0016052 137 100 0,000 0,13609085 0,13609085