pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/26973-3-real-Parker_GPL887-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL887.an.zip classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 3,000 9,979E-11 3,64E-07 ! interphase of mitotic cell cycle GO:0051329 100 81 5,000 3,837E-10 6,999E-07 ! interphase GO:0051325 103 83 5,000 4,456E-10 5,419E-07 ! G2/M transition of mitotic cell cycle GO:0000086 22 16 3,000 2,579E-09 2,352E-06 ! regulation of cyclin-dependent protein kinase activity GO:0000079 55 51 4,000 3,12E-09 2,276E-06 ! regulation of cytokine-mediated signaling pathway GO:0001959 11 6 2,000 2,811E-08 1,709E-05 ! G1/S transition of mitotic cell cycle GO:0000082 54 43 3,000 1,713E-07 8,925E-05 ! midbody GO:0030496 14 12 2,000 3,078E-07 1,404E-04 ! cyclin-dependent protein kinase regulator activity GO:0016538 14 14 2,000 5,085E-07 2,061E-04 ! regulation of protein ubiquitination GO:0031396 27 16 2,000 7,811E-07 2,849E-04 ! spindle microtubule GO:0005876 27 18 2,000 1,136E-06 3,769E-04 ! chaperone binding GO:0051087 21 20 2,000 1,585E-06 4,819E-04 ! cyclin-dependent protein kinase activity GO:0004693 28 27 2,000 4,046E-06 1,135E-03 ! microtubule organizing center part GO:0044450 46 32 2,000 6,835E-06 1,781E-03 ! traversing start control point of mitotic cell cycle GO:0007089 6 5 1,000 1,316E-05 3,2E-03 ! nitric-oxide synthase regulator activity GO:0030235 6 5 1,000 1,316E-05 3E-03 ! negative regulation of fatty acid metabolic process GO:0045922 14 5 1,000 1,316E-05 2,823E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 17 5 1,000 1,316E-05 2,666E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! positive regulation of cell-matrix adhesion GO:0001954 8 5 1,000 1,316E-05 2,526E-03 GO:0010811|positive regulation of cell-substrate adhesion, ! RNA polymerase II carboxy-terminal domain kinase activity GO:0008353 5 5 1,000 1,316E-05 2,4E-03 ! induction of apoptosis by intracellular signals GO:0008629 56 41 2,000 1,459E-05 2,534E-03 ! positive regulation of cell cycle GO:0045787 56 43 2,000 1,686E-05 2,796E-03 ! response to UV GO:0009411 59 45 2,000 1,936E-05 3,071E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 1,972E-05 2,997E-03 ! Hsp90 protein binding GO:0051879 7 6 1,000 1,972E-05 2,878E-03 ! regulation of focal adhesion formation GO:0051893 6 6 1,000 1,972E-05 2,767E-03 ! establishment of chromosome localization GO:0051303 15 6 1,000 1,972E-05 2,664E-03 GO:0050000|chromosome localization, ! negative regulation of protein ubiquitination GO:0031397 7 6 1,000 1,972E-05 2,569E-03 ! cytoplasmic microtubule GO:0005881 7 7 1,000 2,759E-05 3,47E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 8 7 1,000 2,759E-05 3,355E-03 ! positive regulation of mitotic cell cycle GO:0045931 7 7 1,000 2,759E-05 3,247E-03 ! spindle checkpoint GO:0031577 7 7 1,000 2,759E-05 3,145E-03 ! regulation of DNA repair GO:0006282 19 7 1,000 2,759E-05 3,05E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 16 7 1,000 2,759E-05 2,96E-03 ! negative regulation of lipid biosynthetic process GO:0051055 18 8 1,000 3,676E-05 3,831E-03 ! positive regulation of Rho GTPase activity GO:0032321 11 8 1,000 3,676E-05 3,725E-03 ! regulation of actin filament bundle formation GO:0032231 13 8 1,000 3,676E-05 3,624E-03 GO:0051492|regulation of stress fiber formation, ! positive regulation of protein ubiquitination GO:0031398 17 8 1,000 3,676E-05 3,529E-03 ! regulation of fatty acid biosynthetic process GO:0042304 17 8 1,000 3,676E-05 3,438E-03 ! postreplication repair GO:0006301 19 8 1,000 3,676E-05 3,352E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 9 9 1,000 4,723E-05 4,202E-03 ! caspase inhibitor activity GO:0043027 9 9 1,000 4,723E-05 4,102E-03 ! gamma-tubulin complex GO:0000930 19 9 1,000 4,723E-05 4,007E-03 ! response to unfolded protein GO:0006986 66 64 2,000 5,603E-05 4,645E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 12 10 1,000 5,899E-05 4,782E-03 ! positive regulation of Ras GTPase activity GO:0032320 14 10 1,000 5,899E-05 4,678E-03 ! negative regulation of cellular catabolic process GO:0031330 11 10 1,000 5,899E-05 4,579E-03 ! regulation of phosphatase activity GO:0010921 10 10 1,000 5,899E-05 4,483E-03 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 10 10 1,000 5,899E-05 4,392E-03 ! tubulin binding GO:0015631 92 66 2,000 6,144E-05 4,483E-03 ! protein kinase regulator activity GO:0019887 74 66 2,000 6,144E-05 4,395E-03 ! centriole GO:0005814 11 11 1,000 7,205E-05 5,055E-03 ! positive regulation of B cell proliferation GO:0030890 15 11 1,000 7,205E-05 4,959E-03 ! negative regulation of caspase activity GO:0043154 12 11 1,000 7,205E-05 4,867E-03 ! response to protein stimulus GO:0051789 73 70 2,000 7,328E-05 4,86E-03 ! positive regulation of GTPase activity GO:0043547 17 12 1,000 8,64E-05 5,628E-03 ! regulation of exit from mitosis GO:0007096 31 12 1,000 8,64E-05 5,529E-03 ! negative regulation of proteolysis GO:0045861 12 12 1,000 8,64E-05 5,434E-03 ! regulation of cell cycle process GO:0010564 113 75 2,000 9,005E-05 5,568E-03 ! kinase regulator activity GO:0019207 93 76 2,000 9,368E-05 5,696E-03 ! positive regulation of protein modification process GO:0031401 100 78 2,000 1,012E-04 6,053E-03 ! negative regulation of peptidase activity GO:0010466 16 14 1,000 1,19E-04 6,999E-03 ! G1 phase of mitotic cell cycle GO:0000080 15 14 1,000 1,19E-04 6,888E-03 ! regulation of B cell proliferation GO:0030888 18 14 1,000 1,19E-04 6,78E-03 ! regulation of DNA metabolic process GO:0051052 139 84 2,000 1,262E-04 7,083E-03 ! regulation of Rho GTPase activity GO:0032319 18 15 1,000 1,372E-04 7,581E-03 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 1,372E-04 7,468E-03 ! double-strand break repair via homologous recombination GO:0000724 36 15 1,000 1,372E-04 7,358E-03 GO:0000725|recombinational repair, ! centrosome cycle GO:0007098 26 16 1,000 1,566E-04 8,282E-03 ! protein serine/threonine kinase inhibitor activity GO:0030291 17 16 1,000 1,566E-04 8,163E-03 ! G1 phase GO:0051318 17 16 1,000 1,566E-04 8,048E-03 ! spindle GO:0005819 126 92 2,000 1,653E-04 8,376E-03 ! cell cycle arrest GO:0007050 103 93 2,000 1,707E-04 8,53E-03 ! regulation of cytoskeleton organization GO:0051493 133 93 2,000 1,707E-04 8,415E-03 ! regulation of dephosphorylation GO:0035303 20 17 1,000 1,774E-04 8,629E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 17 1,000 1,774E-04 8,515E-03 ! negative regulation of translation GO:0017148 31 18 1,000 1,994E-04 9,448E-03 ! nuclear ubiquitin ligase complex GO:0000152 31 18 1,000 1,994E-04 9,327E-03 ! unfolded protein binding GO:0051082 118 100 2,000 2,116E-04 9,77E-03 ! response to light stimulus GO:0009416 131 100 2,000 2,116E-04 9,648E-03 ! cellular response to unfolded protein GO:0034620 21 19 1,000 2,227E-04 0,01003138 GO:0030968|endoplasmic reticulum unfolded protein response, ! positive regulation of fibroblast proliferation GO:0048146 25 19 1,000 2,227E-04 9,909E-03 ! negative regulation of protein catabolic process GO:0042177 19 19 1,000 2,227E-04 9,79E-03 ! negative regulation of lipid metabolic process GO:0045833 34 20 1,000 2,473E-04 0,01074025 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 33 20 1,000 2,473E-04 0,0106139 ! regulation of cell-matrix adhesion GO:0001952 26 20 1,000 2,473E-04 0,01049048 GO:0010810|regulation of cell-substrate adhesion, ! regulation of nitric oxide biosynthetic process GO:0045428 21 20 1,000 2,473E-04 0,0103699 ! microtubule organizing center organization GO:0031023 33 22 1,000 3,002E-04 0,01244661 GO:0051297|centrosome organization, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 33 22 1,000 3,002E-04 0,01230676 ! positive regulation of B cell activation GO:0050871 26 22 1,000 3,002E-04 0,01217002 ! positive regulation of nuclear division GO:0051785 35 23 1,000 3,286E-04 0,01317321 GO:0045840|positive regulation of mitosis, ! growth cone GO:0030426 27 24 1,000 3,582E-04 0,01420446 ! actin filament GO:0005884 26 24 1,000 3,582E-04 0,01405172 ! androgen receptor binding GO:0050681 34 24 1,000 3,582E-04 0,01390224 ! caspase regulator activity GO:0043028 26 24 1,000 3,582E-04 0,0137559 ! regulation of microtubule cytoskeleton organization GO:0070507 35 24 1,000 3,582E-04 0,01361261 ! site of polarized growth GO:0030427 28 25 1,000 3,891E-04 0,01463335 ! regulation of lipid biosynthetic process GO:0046890 35 25 1,000 3,891E-04 0,01448403 ! positive regulation of cell adhesion GO:0045785 34 26 1,000 4,212E-04 0,01552149 ! regulation of fibroblast proliferation GO:0048145 32 26 1,000 4,212E-04 0,01536628 ! response to endoplasmic reticulum stress GO:0034976 30 26 1,000 4,212E-04 0,01521413 ! RNA export from nucleus GO:0006405 31 27 1,000 4,546E-04 0,0162586 ! fat cell differentiation GO:0045444 30 27 1,000 4,546E-04 0,01610075 ! regulation of fatty acid metabolic process GO:0019217 41 28 1,000 4,892E-04 0,01716033 ! negative regulation of phosphorylation GO:0042326 30 28 1,000 4,892E-04 0,01699689 ! ER-nuclear signaling pathway GO:0006984 32 29 1,000 5,251E-04 0,01807083 ! negative regulation of protein modification process GO:0031400 34 30 1,000 5,622E-04 0,01916701 ! regulation of microtubule-based process GO:0032886 41 30 1,000 5,622E-04 0,01898954 ! negative regulation of phosphorus metabolic process GO:0010563 34 31 1,000 6,005E-04 0,02009862 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of catabolic process GO:0009895 34 31 1,000 6,005E-04 0,01991591 ! regulation of cellular catabolic process GO:0031329 35 31 1,000 6,005E-04 0,01973649 ! response to calcium ion GO:0051592 34 31 1,000 6,005E-04 0,01956027 ! regulation of cellular ketone metabolic process GO:0010565 46 33 1,000 6,809E-04 0,02198251 ! cysteine-type endopeptidase inhibitor activity GO:0004869 35 33 1,000 6,809E-04 0,02178968 ! negative regulation of hydrolase activity GO:0051346 36 34 1,000 7,23E-04 0,0229339 ! regulation of B cell activation GO:0050864 40 34 1,000 7,23E-04 0,02273619 ! steroid hormone receptor binding GO:0035258 44 34 1,000 7,23E-04 0,02254187 ! protein kinase inhibitor activity GO:0004860 37 34 1,000 7,23E-04 0,02235083 ! positive regulation of DNA metabolic process GO:0051054 53 35 1,000 7,662E-04 0,02348951 ! response to estrogen stimulus GO:0043627 48 35 1,000 7,662E-04 0,02329376 ! kinase inhibitor activity GO:0019210 47 35 1,000 7,662E-04 0,02310125 ! regulation of proteolysis GO:0030162 37 35 1,000 7,662E-04 0,02291189 ! androgen receptor signaling pathway GO:0030521 47 35 1,000 7,662E-04 0,02272562 ! cytokinesis GO:0000910 38 35 1,000 7,662E-04 0,02254235 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 44 36 1,000 8,107E-04 0,02366058 ! cellular response to extracellular stimulus GO:0031668 37 36 1,000 8,107E-04 0,0234728 ! positive regulation of mast cell proliferation GO:0070668 43 36 1,000 8,107E-04 0,02328798 GO:0050671|positive regulation of lymphocyte proliferation, ! positive regulation of leukocyte proliferation GO:0070665 47 37 1,000 8,565E-04 0,02440901 GO:0032946|positive regulation of mononuclear cell proliferation, ! double-strand break repair GO:0006302 70 39 1,000 9,515E-04 0,02690894 ! damaged DNA binding GO:0003684 51 40 1,000 1,001E-03 0,02808733 ! lamellipodium GO:0030027 56 41 1,000 1,052E-03 0,02928147 ! nuclear export GO:0051168 46 42 1,000 1,103E-03 0,03049093 ! protein serine/threonine phosphatase activity GO:0004722 45 42 1,000 1,103E-03 0,03026167 ! microtubule binding GO:0008017 61 47 1,000 1,38E-03 0,03757666 ! response to insulin stimulus GO:0032868 57 47 1,000 1,38E-03 0,03729832 ! protein N-terminus binding GO:0047485 57 48 1,000 1,439E-03 0,03860635 ! establishment of organelle localization GO:0051656 58 48 1,000 1,439E-03 0,03832455 ! regulation of gene expression, epigenetic GO:0040029 64 49 1,000 1,499E-03 0,03963766 ! negative regulation of cytoskeleton organization GO:0051494 73 49 1,000 1,499E-03 0,0393525 ! regulation of mast cell proliferation GO:0070666 57 49 1,000 1,499E-03 0,03907141 ! DNA damage response, signal transduction GO:0042770 84 50 1,000 1,561E-03 0,04038202 ! positive regulation of organelle organization GO:0010638 69 51 1,000 1,623E-03 0,04170462 ! regulation of lymphocyte proliferation GO:0050670 61 52 1,000 1,687E-03 0,04303889 ! regulation of protein catabolic process GO:0042176 56 53 1,000 1,752E-03 0,04438453 ! regulation of DNA replication GO:0006275 75 53 1,000 1,752E-03 0,04407843 ! regulation of leukocyte proliferation GO:0070663 65 53 1,000 1,752E-03 0,04377652 GO:0032944|regulation of mononuclear cell proliferation, ! regulation of mitosis GO:0007088 79 55 1,000 1,885E-03 0,04678823 GO:0051783|regulation of nuclear division, ! steroid hormone receptor signaling pathway GO:0030518 70 55 1,000 1,885E-03 0,0464721 ! heat shock protein binding GO:0031072 62 56 1,000 1,954E-03 0,04783583 ! chromosome segregation GO:0007059 92 57 1,000 2,023E-03 0,04920983 ! response to steroid hormone stimulus GO:0048545 74 59 1,000 2,166E-03 0,05233185 ! regulation of cellular response to stress GO:0080135 79 59 1,000 2,166E-03 0,05198756 ! organelle localization GO:0051640 70 59 1,000 2,166E-03 0,05164777 ! cell cycle checkpoint GO:0000075 91 60 1,000 2,239E-03 0,05304409 ! response to metal ion GO:0010038 65 60 1,000 2,239E-03 0,05270187 ! regulation of caspase activity GO:0043281 78 60 1,000 2,239E-03 0,05236403 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 77 62 1,000 2,389E-03 0,05550846 ! positive regulation of protein amino acid phosphorylation GO:0001934 72 62 1,000 2,389E-03 0,05515714 ! intracellular receptor-mediated signaling pathway GO:0030522 80 62 1,000 2,389E-03 0,05481024 ! negative regulation of cell growth GO:0030308 69 63 1,000 2,466E-03 0,05621355 ! regulation of endopeptidase activity GO:0052548 81 63 1,000 2,466E-03 0,0558644 ! negative regulation of protein kinase activity GO:0006469 78 64 1,000 2,543E-03 0,05726981 ! regulation of actin cytoskeleton organization GO:0032956 93 64 1,000 2,543E-03 0,05691846 ! nuclear hormone receptor binding GO:0035257 79 64 1,000 2,543E-03 0,0565714 ! negative regulation of cell size GO:0045792 71 65 1,000 2,622E-03 0,05797237 ! positive regulation of lymphocyte activation GO:0051251 83 65 1,000 2,622E-03 0,05762314 ! response to inorganic substance GO:0010035 71 65 1,000 2,622E-03 0,05727809 ! negative regulation of kinase activity GO:0033673 79 65 1,000 2,622E-03 0,05693715 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 80 65 1,000 2,622E-03 0,05660025 ! regulation of peptidase activity GO:0052547 86 67 1,000 2,783E-03 0,05972615 ! response to peptide hormone stimulus GO:0043434 79 67 1,000 2,783E-03 0,05937688 ! regulation of actin filament-based process GO:0032970 96 67 1,000 2,783E-03 0,05903166 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 83 67 1,000 2,783E-03 0,05869044 ! negative regulation of organelle organization GO:0010639 93 68 1,000 2,866E-03 0,06007873 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 84 68 1,000 2,866E-03 0,05973542 ! positive regulation of ligase activity GO:0051351 86 70 1,000 3,034E-03 0,06287874 ! negative regulation of transferase activity GO:0051348 85 70 1,000 3,034E-03 0,06252349 ! hormone receptor binding GO:0051427 85 70 1,000 3,034E-03 0,06217224 ! positive regulation of phosphorylation GO:0042327 82 70 1,000 3,034E-03 0,06182491 ! cell cortex GO:0005938 77 70 1,000 3,034E-03 0,06148144 ! positive regulation of phosphorus metabolic process GO:0010562 85 72 1,000 3,206E-03 0,06461968 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of leukocyte activation GO:0002696 92 73 1,000 3,294E-03 0,066028 ! regulation of Rho protein signal transduction GO:0035023 88 73 1,000 3,294E-03 0,06566719 ! ubiquitin ligase complex GO:0000151 91 74 1,000 3,383E-03 0,06707683 ! positive regulation of cell activation GO:0050867 94 75 1,000 3,473E-03 0,06849339 ! regulation of ubiquitin-protein ligase activity GO:0051438 92 75 1,000 3,473E-03 0,06812515 ! negative regulation of growth GO:0045926 85 76 1,000 3,565E-03 0,06954283 ! regulation of lipid metabolic process GO:0019216 98 76 1,000 3,565E-03 0,06917292 ! cell leading edge GO:0031252 97 76 1,000 3,565E-03 0,06880692 ! condensed chromosome GO:0000793 106 76 1,000 3,565E-03 0,06844478 ! regulation of Ras GTPase activity GO:0032318 88 77 1,000 3,657E-03 0,06985246 ! establishment of RNA localization GO:0051236 97 77 1,000 3,657E-03 0,06948865 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! regulation of ligase activity GO:0051340 95 78 1,000 3,751E-03 0,07089743 ! RNA localization GO:0006403 99 79 1,000 3,846E-03 0,07231263 ! regulation of catabolic process GO:0009894 87 80 1,000 3,941E-03 0,0737341 ! chromosome, centromeric region GO:0000775 119 80 1,000 3,941E-03 0,0733579 ! regulation of cell adhesion GO:0030155 98 83 1,000 4,235E-03 0,07843084 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 101 83 1,000 4,235E-03 0,07803473 GO:0010498|proteasomal protein catabolic process, ! DNA recombination GO:0006310 147 84 1,000 4,336E-03 0,07947989 ! microtubule cytoskeleton organization GO:0000226 113 87 1,000 4,643E-03 0,08468688 ! pigment granule GO:0048770 101 87 1,000 4,643E-03 0,08426555 GO:0042470|melanosome, ! protein tyrosine phosphatase activity GO:0004725 109 89 1,000 4,853E-03 0,08764627 ! protein kinase binding GO:0019901 115 89 1,000 4,853E-03 0,08721451 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 112 91 1,000 5,068E-03 0,09062534 ! regulation of cellular component biogenesis GO:0044087 115 92 1,000 5,177E-03 0,09212196 ! regulation of GTPase activity GO:0043087 105 92 1,000 5,177E-03 0,09167477 ! perinuclear region of cytoplasm GO:0048471 125 97 1,000 5,738E-03 0,10111608 ! positive regulation of epidermal growth factor receptor activity GO:0045741 6 5 0,000 5,863E-03 0,10282622 ! negative regulation of S phase of mitotic cell cycle GO:0045749 5 5 0,000 5,863E-03 0,10233422 ! positive regulation of fatty acid biosynthetic process GO:0045723 5 5 0,000 5,863E-03 0,10184692 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 6 5 0,000 5,863E-03 0,10136423 ! response to superoxide GO:0000303 5 5 0,000 5,863E-03 0,1008861 ! negative regulation of small GTPase mediated signal transduction GO:0051058 6 5 0,000 5,863E-03 0,10041245 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 6 5 0,000 5,863E-03 0,09994324 GO:0032479|regulation of type I interferon production, ! regulation of hormone biosynthetic process GO:0046885 5 5 0,000 5,863E-03 0,09947839 ! calcium:cation antiporter activity GO:0015368 5 5 0,000 5,863E-03 0,09901784 ! quinolinate metabolic process GO:0046874 5 5 0,000 5,863E-03 0,09856153 ! biotin binding GO:0009374 7 5 0,000 5,863E-03 0,09810942 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 5,863E-03 0,09766143 ! tongue development GO:0043586 6 5 0,000 5,863E-03 0,09721751 ! nose development GO:0043584 5 5 0,000 5,863E-03 0,09677761 ! cell proliferation in forebrain GO:0021846 5 5 0,000 5,863E-03 0,09634168 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 5 5 0,000 5,863E-03 0,09590965 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 5,863E-03 0,09548149 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 5 0,000 5,863E-03 0,09505712 ! drug:hydrogen antiporter activity GO:0015307 6 5 0,000 5,863E-03 0,09463652 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! nuclear mRNA 3'-splice site recognition GO:0000389 6 5 0,000 5,863E-03 0,09421962 ! glycolipid transport GO:0046836 6 5 0,000 5,863E-03 0,09380637 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 6 5 0,000 5,863E-03 0,09339674 ! regulation of respiratory gaseous exchange GO:0043576 6 5 0,000 5,863E-03 0,09299066 ! regulation of protein export from nucleus GO:0046825 5 5 0,000 5,863E-03 0,09258811 ! neuron adhesion GO:0007158 5 5 0,000 5,863E-03 0,09218902 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 5 5 0,000 5,863E-03 0,09179336 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 5 0,000 5,863E-03 0,09140108 ! opioid peptide activity GO:0001515 6 5 0,000 5,863E-03 0,09101214 ! selenocysteine incorporation GO:0001514 5 5 0,000 5,863E-03 0,0906265 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 6 5 0,000 5,863E-03 0,0902441 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 8 5 0,000 5,863E-03 0,08986493 ! cardiac muscle cell proliferation GO:0060038 6 5 0,000 5,863E-03 0,08948892 GO:0014855|striated muscle cell proliferation, ! dsRNA fragmentation GO:0031050 6 5 0,000 5,863E-03 0,08911605 GO:0035196|gene silencing by miRNA, production of miRNAs, GO:0035195|gene silencing by miRNA, ! ruffle membrane GO:0032587 6 5 0,000 5,863E-03 0,08874628 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 5,863E-03 0,08837956 ! negative regulation of receptor-mediated endocytosis GO:0048261 7 5 0,000 5,863E-03 0,08801586 ! clathrin coat assembly GO:0048268 6 5 0,000 5,863E-03 0,08765513 ! cerebral cortex cell migration GO:0021795 5 5 0,000 5,863E-03 0,08729736 ! eukaryotic translation elongation factor 1 complex GO:0005853 5 5 0,000 5,863E-03 0,08694249 ! membrane hyperpolarization GO:0060081 5 5 0,000 5,863E-03 0,0865905 ! regulation of striated muscle cell differentiation GO:0051153 6 5 0,000 5,863E-03 0,08624134 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 5,863E-03 0,08589499 ! translation repressor activity GO:0030371 8 5 0,000 5,863E-03 0,08555141 ! positive regulation of muscle cell differentiation GO:0051149 6 5 0,000 5,863E-03 0,08521057 ! smooth muscle cell differentiation GO:0051145 6 5 0,000 5,863E-03 0,08487243 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 5,863E-03 0,08453697 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 5 5 0,000 5,863E-03 0,08420415 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 5,863E-03 0,08387393 GO:0046329|negative regulation of JNK cascade, ! double-stranded telomeric DNA binding GO:0003691 6 5 0,000 5,863E-03 0,0835463 ! negative regulation of heart contraction GO:0045822 5 5 0,000 5,863E-03 0,08322122 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 5,863E-03 0,08289865 ! microfibril GO:0001527 5 5 0,000 5,863E-03 0,08257858 ! troponin I binding GO:0031013 5 5 0,000 5,863E-03 0,08226097 ! negative regulation of viral genome replication GO:0045071 6 5 0,000 5,863E-03 0,0819458 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 5,863E-03 0,08163303 ! dorsal/ventral neural tube patterning GO:0021904 5 5 0,000 5,863E-03 0,08132263 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 5,863E-03 0,08101459 ! protein lipoylation GO:0009249 14 5 0,000 5,863E-03 0,08070888 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 5,863E-03 0,08040546 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 5,863E-03 0,08010432 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of isotype switching to IgG isotypes GO:0048302 5 5 0,000 5,863E-03 0,07980542 ! transmembrane-ephrin receptor activity GO:0005005 6 5 0,000 5,863E-03 0,07950875 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 5,863E-03 0,07921427 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 5,863E-03 0,07892197 ! glutamate catabolic process GO:0006538 6 5 0,000 5,863E-03 0,07863181 ! microvillus organization GO:0032528 5 5 0,000 5,863E-03 0,07834378 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 6 5 0,000 5,863E-03 0,07805786 ! tyrosine catabolic process GO:0006572 5 5 0,000 5,863E-03 0,07777401 ! response to pH GO:0009268 5 5 0,000 5,863E-03 0,07749222 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 5 0,000 5,863E-03 0,07721247 ! regulation of protein import into nucleus, translocation GO:0033158 5 5 0,000 5,863E-03 0,07693472 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 5,863E-03 0,07665897 ! polyol biosynthetic process GO:0046173 5 5 0,000 5,863E-03 0,07638519 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 7 5 0,000 5,863E-03 0,07611336 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 5,863E-03 0,07584345 ! fibroblast growth factor receptor activity GO:0005007 6 5 0,000 5,863E-03 0,07557545 ! protein-DNA loading ATPase activity GO:0033170 6 5 0,000 5,863E-03 0,07530934 GO:0003689|DNA clamp loader activity, ! mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276 5 5 0,000 5,863E-03 0,0750451 ! anaerobic glycolysis GO:0019642 5 5 0,000 5,863E-03 0,0747827 GO:0004459|L-lactate dehydrogenase activity, ! adenosine receptor activity, G-protein coupled GO:0001609 6 5 0,000 5,863E-03 0,07452214 ! regulation of retinoic acid receptor signaling pathway GO:0048385 6 5 0,000 5,863E-03 0,07426338 ! peroxisomal matrix GO:0005782 5 5 0,000 5,863E-03 0,07400641 GO:0031907|microbody lumen, ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 5,863E-03 0,07375122 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 6 5 0,000 5,863E-03 0,07349778 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 5,863E-03 0,07324607 ! multivesicular body GO:0005771 5 5 0,000 5,863E-03 0,07299608 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 5,863E-03 0,0727478 GO:0032430|positive regulation of phospholipase A2 activity, ! paraxial mesoderm formation GO:0048341 6 5 0,000 5,863E-03 0,0725012 ! insulin-like growth factor I binding GO:0031994 6 5 0,000 5,863E-03 0,07225626 ! mitochondrial outer membrane translocase complex GO:0005742 5 5 0,000 5,863E-03 0,07201297 ! peptidyl-histidine phosphorylation GO:0018106 6 5 0,000 5,863E-03 0,07177132 ! negative regulation of lipoprotein lipase activity GO:0051005 5 5 0,000 5,863E-03 0,07153128 ! epithelial cell maturation GO:0002070 14 5 0,000 5,863E-03 0,07129284 ! positive regulation of lipoprotein lipase activity GO:0051006 6 5 0,000 5,863E-03 0,07105599 ! muscle thin filament assembly GO:0030240 5 5 0,000 5,863E-03 0,0708207 ! regulation of protein amino acid autophosphorylation GO:0031952 5 5 0,000 5,863E-03 0,07058697 ! regulation of glycoprotein biosynthetic process GO:0010559 6 5 0,000 5,863E-03 0,07035478 ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,863E-03 0,07012411 ! positive regulation of translational initiation GO:0045948 6 5 0,000 5,863E-03 0,06989494 ! nonhomologous end joining complex GO:0070419 6 5 0,000 5,863E-03 0,06966727 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! depyrimidination GO:0045008 5 5 0,000 5,863E-03 0,06944108 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 5,863E-03 0,06921635 ! ATPase activator activity GO:0001671 5 5 0,000 5,863E-03 0,06899307 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 5,863E-03 0,06877123 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! calcium sensitive guanylate cyclase activator activity GO:0008048 5 5 0,000 5,863E-03 0,06855081 ! regulation of cholesterol biosynthetic process GO:0045540 5 5 0,000 5,863E-03 0,0683318 ! positive regulation of collagen metabolic process GO:0010714 6 5 0,000 5,863E-03 0,06811418 GO:0032967|positive regulation of collagen biosynthetic process, ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 7 5 0,000 5,863E-03 0,06789795 ! regulation of protein amino acid dephosphorylation GO:0035304 7 5 0,000 5,863E-03 0,06768308 ! cardiac myofibril assembly GO:0055003 5 5 0,000 5,863E-03 0,06746957 ! anterograde axon cargo transport GO:0008089 6 5 0,000 5,863E-03 0,0672574 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,863E-03 0,06704656 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 5,863E-03 0,06683704 GO:0003923|GPI-anchor transamidase activity, ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 5,863E-03 0,06662883 ! thiamin and derivative metabolic process GO:0042723 5 5 0,000 5,863E-03 0,0664219 ! protein localization to telomere GO:0070198 7 5 0,000 5,863E-03 0,06621626 ! response to exogenous dsRNA GO:0043330 5 5 0,000 5,863E-03 0,06601189 ! MutSalpha complex binding GO:0032407 7 5 0,000 5,863E-03 0,06580878 ! bile acid biosynthetic process GO:0006699 5 5 0,000 5,863E-03 0,06560691 ! negative regulation of fat cell differentiation GO:0045599 6 5 0,000 5,863E-03 0,06540628 ! enucleate erythrocyte differentiation GO:0043353 7 5 0,000 5,863E-03 0,06520687 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 5,863E-03 0,06500867 ! nerve growth factor binding GO:0048406 7 5 0,000 5,863E-03 0,06481168 ! platelet-derived growth factor binding GO:0048407 8 5 0,000 5,863E-03 0,06461587 ! high-density lipoprotein binding GO:0008035 6 5 0,000 5,863E-03 0,06442124 ! negative regulation of focal adhesion formation GO:0051895 5 5 0,000 5,863E-03 0,06422779 ! transcription initiation factor activity GO:0016986 5 5 0,000 5,863E-03 0,06403549 ! gas homeostasis GO:0033483 5 5 0,000 5,863E-03 0,06384434 ! Schwann cell development GO:0014044 5 5 0,000 5,863E-03 0,06365432 ! CD4-positive, alpha beta T cell differentiation GO:0043367 5 5 0,000 5,863E-03 0,06346544 ! cyclohydrolase activity GO:0019238 5 5 0,000 5,863E-03 0,06327767 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 5,863E-03 0,06309101 ! response to pheromone GO:0019236 5 5 0,000 5,863E-03 0,06290545 GO:0016503|pheromone receptor activity, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 5 5 0,000 5,863E-03 0,06272098 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 5,863E-03 0,06253758 ! rhombomere development GO:0021546 6 5 0,000 5,863E-03 0,06235526 ! alanine transport GO:0032328 6 5 0,000 5,863E-03 0,06217399 ! superoxide-generating NADPH oxidase activity GO:0016175 5 5 0,000 5,863E-03 0,06199378 ! NAD(P)H oxidase activity GO:0016174 5 5 0,000 5,863E-03 0,0618146 ! ventral spinal cord interneuron specification GO:0021521 7 5 0,000 5,863E-03 0,06163646 GO:0021514|ventral spinal cord interneuron differentiation, GO:0060579|ventral spinal cord interneuron fate commitment, ! spinal cord motor neuron cell fate specification GO:0021520 6 5 0,000 5,863E-03 0,06145935 ! regulation of meiosis GO:0040020 6 5 0,000 5,863E-03 0,06128325 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 6 5 0,000 5,863E-03 0,06110815 GO:0000085|G2 phase of mitotic cell cycle, ! parasympathetic nervous system development GO:0048486 5 5 0,000 5,863E-03 0,06093405 ! lymphocyte costimulation GO:0031294 5 5 0,000 5,863E-03 0,06076095 GO:0031295|T cell costimulation, ! response to tumor cell GO:0002347 7 5 0,000 5,863E-03 0,06058882 ! RS domain binding GO:0050733 6 5 0,000 5,863E-03 0,06041766 ! telomerase holoenzyme complex GO:0005697 6 5 0,000 5,863E-03 0,06024747 ! negative regulation of lipoprotein metabolic process GO:0050748 6 5 0,000 5,863E-03 0,06007824 ! B cell homeostasis GO:0001782 6 5 0,000 5,863E-03 0,05990995 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 5,863E-03 0,05974261 ! anaphase GO:0051322 7 5 0,000 5,863E-03 0,05957619 GO:0000090|mitotic anaphase, ! S phase GO:0051320 5 5 0,000 5,863E-03 0,0594107 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 5,863E-03 0,05924613 GO:0050820|positive regulation of coagulation, ! ribonuclease H activity GO:0004523 14 5 0,000 5,863E-03 0,05908247 ! AP-2 adaptor complex GO:0030122 5 5 0,000 5,863E-03 0,0589197 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 6 5 0,000 5,863E-03 0,05875784 ! diuresis GO:0030146 5 5 0,000 5,863E-03 0,05859686 GO:0030147|natriuresis, ! phosphatidylcholine binding GO:0031210 5 5 0,000 5,863E-03 0,05843676 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 5,863E-03 0,05827753 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 5,863E-03 0,05811917 ! very-low-density lipoprotein particle clearance GO:0034447 6 5 0,000 5,863E-03 0,05796166 ! GTP-Rho binding GO:0017049 5 5 0,000 5,863E-03 0,05780501 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 5,863E-03 0,0576492 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 5,863E-03 0,05749423 ! chondroitin sulfotransferase activity GO:0034481 6 5 0,000 5,863E-03 0,05734009 ! brown fat cell differentiation GO:0050873 5 5 0,000 5,863E-03 0,05718677 ! regulation of telomerase activity GO:0051972 6 5 0,000 5,863E-03 0,05703427 ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 5,863E-03 0,05688259 ! TAP complex GO:0042825 5 5 0,000 5,863E-03 0,05673171 ! platelet dense granule GO:0042827 6 5 0,000 5,863E-03 0,05658162 ! bHLH transcription factor binding GO:0043425 5 5 0,000 5,863E-03 0,05643233 ! secretory granule organization GO:0033363 5 5 0,000 5,863E-03 0,05628382 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 14 5 0,000 5,863E-03 0,0561361 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 5,863E-03 0,05598914 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 5,863E-03 0,05584296 ! lamin binding GO:0005521 8 5 0,000 5,863E-03 0,05569753 ! aldehyde-lyase activity GO:0016832 6 5 0,000 5,863E-03 0,05555286 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 5,863E-03 0,05540895 ! neural plate morphogenesis GO:0001839 6 5 0,000 5,863E-03 0,05526577 ! cyclosporin A binding GO:0016018 6 5 0,000 5,863E-03 0,05512333 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 5,863E-03 0,05498163 ! negative regulation of fibrinolysis GO:0051918 5 5 0,000 5,863E-03 0,05484065 ! positive regulation of telomere maintenance GO:0032206 7 5 0,000 5,863E-03 0,05470039 ! pattern recognition receptor signaling pathway GO:0002221 5 5 0,000 5,863E-03 0,05456085 GO:0002224|toll-like receptor signaling pathway, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 5 5 0,000 5,863E-03 0,05442202 ! positive regulation of blood vessel endothelial cell migration GO:0043536 6 5 0,000 5,863E-03 0,05428389 ! flavin-containing monooxygenase activity GO:0004499 6 5 0,000 5,863E-03 0,05414646 ! regulation of calcium ion transport via store-operated calcium channel activity GO:0032234 5 5 0,000 5,863E-03 0,05400973 ! hemopoietic progenitor cell differentiation GO:0002244 6 5 0,000 5,863E-03 0,05387368 ! organ or tissue specific immune response GO:0002251 6 5 0,000 5,863E-03 0,05373832 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 5,863E-03 0,05360364 ! retina homeostasis GO:0001895 5 5 0,000 5,863E-03 0,05346963 ! prepulse inhibition GO:0060134 8 5 0,000 5,863E-03 0,05333629 ! maternal placenta development GO:0001893 5 5 0,000 5,863E-03 0,05320361 GO:0046697|decidualization, ! endothelial cell development GO:0001885 6 5 0,000 5,863E-03 0,0530716 ! regulation of growth hormone secretion GO:0060123 5 5 0,000 5,863E-03 0,05294023 GO:0060124|positive regulation of growth hormone secretion, ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 5,863E-03 0,05280951 ! thiamin pyrophosphate binding GO:0030976 5 5 0,000 5,863E-03 0,05267944 ! protein palmitoylation GO:0018345 5 5 0,000 5,863E-03 0,05255001 ! protein amino acid prenylation GO:0018346 6 5 0,000 5,863E-03 0,05242121 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 5 0,000 5,863E-03 0,05229304 ! stem cell division GO:0017145 6 5 0,000 5,863E-03 0,05216549 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 5,863E-03 0,05203857 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 6 5 0,000 5,863E-03 0,05191226 ! organ regeneration GO:0031100 6 5 0,000 5,863E-03 0,05178657 ! lymphocyte apoptosis GO:0070227 6 5 0,000 5,863E-03 0,05166148 ! positive regulation of microtubule polymerization GO:0031116 5 5 0,000 5,863E-03 0,05153699 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 5,863E-03 0,05141311 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of developmental growth GO:0048639 6 5 0,000 5,863E-03 0,05128982 ! acyl carrier activity GO:0000036 5 5 0,000 5,863E-03 0,05116711 ! positive regulation of cAMP biosynthetic process GO:0030819 6 5 0,000 5,863E-03 0,05104499 GO:0030816|positive regulation of cAMP metabolic process, ! condensin complex GO:0000796 6 5 0,000 5,863E-03 0,05092346 ! phagocytic vesicle GO:0045335 5 5 0,000 5,863E-03 0,0508025 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 5,863E-03 0,05068212 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 5,863E-03 0,0505623 GO:0030823|regulation of cGMP metabolic process, ! citrulline metabolic process GO:0000052 14 5 0,000 5,863E-03 0,05044305 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 5,863E-03 0,05032436 ! polyol transport GO:0015791 8 5 0,000 5,863E-03 0,05020623 ! post-embryonic morphogenesis GO:0009886 7 5 0,000 5,863E-03 0,05008865 ! pyrimidine nucleotide-sugar transport GO:0015781 5 5 0,000 5,863E-03 0,04997162 ! regulation of cell adhesion mediated by integrin GO:0033628 5 5 0,000 5,863E-03 0,04985513 ! cell adhesion mediated by integrin GO:0033627 5 5 0,000 5,863E-03 0,04973919 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 5,863E-03 0,04962379 ! glycerol-3-phosphate metabolic process GO:0006072 6 5 0,000 5,863E-03 0,04950892 ! ethanol metabolic process GO:0006067 6 5 0,000 5,863E-03 0,04939458 GO:0006069|ethanol oxidation, GO:0034308|monohydric alcohol metabolic process, ! phosphatidic acid metabolic process GO:0046473 5 5 0,000 5,863E-03 0,04928077 ! cobalt ion transport GO:0006824 5 5 0,000 5,863E-03 0,04916748 ! cellular zinc ion homeostasis GO:0006882 6 5 0,000 5,863E-03 0,04905471 ! Golgi to plasma membrane transport GO:0006893 7 5 0,000 5,863E-03 0,04894246 ! syncytium formation by plasma membrane fusion GO:0000768 5 5 0,000 5,863E-03 0,04883071 GO:0007520|myoblast fusion, ! poly(U) RNA binding GO:0008266 5 5 0,000 5,863E-03 0,04871948 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 5 5 0,000 5,863E-03 0,04860876 ! sterol carrier activity GO:0005498 6 5 0,000 5,863E-03 0,04849853 ! adaptation of signaling pathway GO:0022401 6 5 0,000 5,863E-03 0,04838881 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 6 5 0,000 5,863E-03 0,04827958 ! response to acid GO:0001101 7 5 0,000 5,863E-03 0,04817084 ! fibril organization GO:0043206 5 5 0,000 5,863E-03 0,04806259 ! malate metabolic process GO:0006108 6 5 0,000 5,863E-03 0,04795483 ! regulation of dopamine uptake GO:0051584 7 5 0,000 5,863E-03 0,04784755 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! copulation GO:0007620 5 5 0,000 5,863E-03 0,04774074 ! circadian sleep/wake cycle process GO:0022410 5 5 0,000 5,863E-03 0,04763442 GO:0042749|regulation of circadian sleep/wake cycle, GO:0045187|regulation of circadian sleep/wake cycle, sleep, ! cleavage furrow GO:0032154 6 5 0,000 5,863E-03 0,04752856 ! protein maturation by protein folding GO:0022417 5 5 0,000 5,863E-03 0,04742318 ! activation of protein kinase B activity GO:0032148 15 5 0,000 5,863E-03 0,04731826 ! origin recognition complex GO:0000808 5 5 0,000 5,863E-03 0,0472138 ! neurexin binding GO:0042043 6 5 0,000 5,863E-03 0,04710981 ! sensory perception of temperature stimulus GO:0050951 8 5 0,000 5,863E-03 0,04700627 ! protein amino acid dealkylation GO:0008214 5 5 0,000 5,863E-03 0,04690319 GO:0006482|protein amino acid demethylation, ! NF-kappaB-inducing kinase activity GO:0004704 5 5 0,000 5,863E-03 0,04680055 ! lipoic acid binding GO:0031405 5 5 0,000 5,863E-03 0,04669837 ! very-low-density lipoprotein particle assembly GO:0034379 5 5 0,000 5,863E-03 0,04659663 ! lithium ion binding GO:0031403 6 5 0,000 5,863E-03 0,04649533 ! grooming behavior GO:0007625 7 5 0,000 5,863E-03 0,04639447 ! regulation of smooth muscle cell apoptosis GO:0034391 5 5 0,000 5,863E-03 0,04629405 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 5,863E-03 0,04619407 ! lymph vessel development GO:0001945 6 5 0,000 5,863E-03 0,04609451 ! bicarbonate transport GO:0015701 5 5 0,000 5,863E-03 0,04599538 ! response to interferon-gamma GO:0034341 6 5 0,000 5,863E-03 0,04589668 ! protein-lysine 6-oxidase activity GO:0004720 23 5 0,000 5,863E-03 0,0457984 ! endothelial cell proliferation GO:0001935 8 5 0,000 5,863E-03 0,04570054 ! polynucleotide adenylyltransferase activity GO:0004652 5 5 0,000 5,863E-03 0,0456031 ! dorsal spinal cord development GO:0021516 6 5 0,000 5,863E-03 0,04550607 ! activation of MAPKKK activity GO:0000185 5 5 0,000 5,863E-03 0,04540945 ! synaptic vesicle maturation GO:0016188 6 5 0,000 5,863E-03 0,04531325 ! sphingoid catabolic process GO:0046521 5 5 0,000 5,863E-03 0,04521745 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 5,863E-03 0,04512205 ! neutrophil mediated immunity GO:0002446 5 5 0,000 5,863E-03 0,04502706 ! intercellular canaliculus GO:0046581 5 5 0,000 5,863E-03 0,04493246 ! dopamine binding GO:0035240 7 5 0,000 5,863E-03 0,04483827 GO:0004952|dopamine receptor activity, ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 5 5 0,000 5,863E-03 0,04474446 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 5 5 0,000 5,863E-03 0,04465105 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 6 5 0,000 5,863E-03 0,04455803 ! amine oxidase activity GO:0008131 7 5 0,000 5,863E-03 0,04446539 ! monocyte activation GO:0042117 9 5 0,000 5,863E-03 0,04437314 ! negative regulation of protein binding GO:0032091 5 5 0,000 5,863E-03 0,04428127 ! regulation of response to food GO:0032095 5 5 0,000 5,863E-03 0,04418978 ! response to food GO:0032094 6 5 0,000 5,863E-03 0,04409867 ! positive regulation of protein binding GO:0032092 5 5 0,000 5,863E-03 0,04400793 ! copper ion transmembrane transporter activity GO:0005375 5 5 0,000 5,863E-03 0,04391756 ! regulation of ryanodine-sensitive calcium-release channel activity GO:0060314 6 5 0,000 5,863E-03 0,04382757 ! hedgehog receptor activity GO:0008158 5 5 0,000 5,863E-03 0,04373794 ! lipoprotein catabolic process GO:0042159 5 5 0,000 5,863E-03 0,04364868 ! substrate-bound cell migration, cell extension GO:0006930 7 5 0,000 5,863E-03 0,04355978 ! purine salvage GO:0043101 7 5 0,000 5,863E-03 0,04347125 ! small-subunit processome GO:0032040 5 5 0,000 5,863E-03 0,04338307 ! positive regulation of catecholamine secretion GO:0033605 5 5 0,000 5,863E-03 0,04329525 ! ciliary rootlet GO:0035253 5 5 0,000 5,863E-03 0,04320778 ! myosin heavy chain binding GO:0032036 5 5 0,000 5,863E-03 0,04312067 ! nucleobase transport GO:0015851 5 5 0,000 5,863E-03 0,04303391 ! sodium ion transmembrane transporter activity GO:0015081 6 5 0,000 5,863E-03 0,0429475 ! GPI anchor binding GO:0034235 6 5 0,000 5,863E-03 0,04286143 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,863E-03 0,04277571 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! thrombin receptor activity GO:0015057 5 5 0,000 5,863E-03 0,04269033 ! palmitoyl-CoA hydrolase activity GO:0016290 5 5 0,000 5,863E-03 0,04260528 ! basic amino acid transport GO:0015802 5 5 0,000 5,863E-03 0,04252058 ! dendritic shaft GO:0043198 5 5 0,000 5,863E-03 0,04243622 ! terminal button GO:0043195 7 5 0,000 5,863E-03 0,04235218 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 5,863E-03 0,04226848 GO:0016274|protein-arginine N-methyltransferase activity, ! neuronal ion channel clustering GO:0045161 5 5 0,000 5,863E-03 0,04218511 ! transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity GO:0030618 6 5 0,000 5,863E-03 0,04210207 ! homeostasis of number of cells within a tissue GO:0048873 7 5 0,000 5,863E-03 0,04201936 ! negative regulation of peptide secretion GO:0002792 5 5 0,000 5,863E-03 0,04193697 GO:0046676|negative regulation of insulin secretion, ! neural nucleus development GO:0048857 6 5 0,000 5,863E-03 0,0418549 ! response to UV-C GO:0010225 15 5 0,000 5,863E-03 0,04177315 ! positive regulation of organ growth GO:0046622 5 5 0,000 5,863E-03 0,04169172 ! response to arsenic GO:0046685 6 5 0,000 5,863E-03 0,04161061 ! IgE binding GO:0019863 5 5 0,000 5,863E-03 0,04152981 ! positive regulation of T cell cytokine production GO:0002726 5 5 0,000 5,863E-03 0,04144933 GO:0032743|positive regulation of interleukin-2 production, ! transcription-coupled nucleotide-excision repair GO:0006283 5 5 0,000 5,863E-03 0,04136915 ! monoamine transmembrane transporter activity GO:0008504 6 5 0,000 5,863E-03 0,04128929 ! response to copper ion GO:0046688 5 5 0,000 5,863E-03 0,04120974 ! response to cadmium ion GO:0046686 5 5 0,000 5,863E-03 0,04113049 ! tetrahydrofolate metabolic process GO:0046653 5 5 0,000 5,863E-03 0,04105154 ! regulation of interleukin-1 beta production GO:0032651 5 5 0,000 5,863E-03 0,0409729 ! protein autoprocessing GO:0016540 6 5 0,000 5,863E-03 0,04089456 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 5,863E-03 0,04081651 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 5,863E-03 0,04073877 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 5,863E-03 0,04066132 GO:0005218|intracellular ligand-gated calcium channel activity, ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 5,863E-03 0,04058416 ! mitotic recombination GO:0006312 15 5 0,000 5,863E-03 0,0405073 ! negative regulation of interleukin-6 production GO:0032715 6 5 0,000 5,863E-03 0,04043072 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 5,863E-03 0,04035444 ! membrane to membrane docking GO:0022614 5 5 0,000 5,863E-03 0,04027844 ! regulation of transcription from RNA polymerase I promoter GO:0006356 14 5 0,000 5,863E-03 0,04020273 ! translation activator activity GO:0008494 5 5 0,000 5,863E-03 0,0401273 ! somatostatin receptor activity GO:0004994 5 5 0,000 5,863E-03 0,04005216 ! melanocortin receptor activity GO:0004977 6 5 0,000 5,863E-03 0,0399773 ! serine-type carboxypeptidase activity GO:0004185 5 5 0,000 5,863E-03 0,03990271 GO:0070008|serine-type exopeptidase activity, ! protein phosphatase 2A binding GO:0051721 6 5 0,000 5,863E-03 0,0398284 ! salivary gland morphogenesis GO:0007435 5 5 0,000 5,863E-03 0,03975437 ! galactosidase activity GO:0015925 5 5 0,000 5,863E-03 0,03968062 ! prostaglandin E receptor activity GO:0004957 7 5 0,000 5,863E-03 0,03960713 ! cellular response to nutrient GO:0031670 5 5 0,000 5,863E-03 0,03953392 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 5,863E-03 0,03946098 ! L-cystine transmembrane transporter activity GO:0015184 5 5 0,000 5,863E-03 0,03938831 ! glycine transmembrane transporter activity GO:0015187 7 5 0,000 5,863E-03 0,03931591 ! L-gamma-aminobutyric acid transmembrane transporter activity GO:0015185 6 5 0,000 5,863E-03 0,03924377 ! A band GO:0031672 5 5 0,000 5,863E-03 0,03917189 ! heat generation GO:0031649 5 5 0,000 5,863E-03 0,03910028 ! flagellum organization GO:0043064 5 5 0,000 5,863E-03 0,03902893 GO:0009296|flagellum assembly, ! tricarboxylic acid cycle enzyme complex GO:0045239 6 5 0,000 5,863E-03 0,03895784 ! disaccharide metabolic process GO:0005984 6 5 0,000 5,863E-03 0,03888701 ! glycogen catabolic process GO:0005980 16 5 0,000 5,863E-03 0,03881643 ! dopamine biosynthetic process GO:0042416 6 5 0,000 5,863E-03 0,03874611 ! 5'-3' exonuclease activity GO:0008409 14 5 0,000 5,863E-03 0,03867604 ! chromocenter GO:0010369 5 5 0,000 5,863E-03 0,03860623 ! glial cell migration GO:0008347 5 5 0,000 5,863E-03 0,03853667 ! epidermal growth factor receptor binding GO:0005154 7 5 0,000 5,863E-03 0,03846736 ! calcium-dependent phospholipase A2 activity GO:0047498 5 5 0,000 5,863E-03 0,0383983 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 5,863E-03 0,03832949 ! growth hormone receptor binding GO:0005131 5 5 0,000 5,863E-03 0,03826092 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 5,863E-03 0,03819259 ! negative regulation of smooth muscle contraction GO:0045986 7 5 0,000 5,863E-03 0,03812451 ! aminomethyltransferase activity GO:0004047 5 5 0,000 5,863E-03 0,03805668 ! aminoacylase activity GO:0004046 5 5 0,000 5,863E-03 0,03798908 ! penetration of zona pellucida GO:0007341 6 5 0,000 5,863E-03 0,03792172 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 5 5 0,000 5,863E-03 0,03785461 ! nucleus localization GO:0051647 5 5 0,000 5,863E-03 0,03778773 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 5 5 0,000 5,863E-03 0,03772108 ! carnitine metabolic process GO:0009437 5 5 0,000 5,863E-03 0,03765467 GO:0006577|betaine metabolic process, ! negative regulation of cellular component organization GO:0051129 132 99 1,000 5,97E-03 0,03827196 ! regulation of lymphocyte activation GO:0051249 123 100 1,000 6,087E-03 0,03895687 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 7,032E-03 0,044923 ! regulation of helicase activity GO:0051095 6 6 0,000 7,032E-03 0,04484447 ! response to oxygen radical GO:0000305 6 6 0,000 7,032E-03 0,04476621 ! positive regulation of axon extension GO:0045773 7 6 0,000 7,032E-03 0,04468822 ! forebrain neuron differentiation GO:0021879 6 6 0,000 7,032E-03 0,0446105 ! forebrain regionalization GO:0021871 7 6 0,000 7,032E-03 0,04453305 ! meiotic prophase I GO:0007128 7 6 0,000 7,032E-03 0,04445587 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 7,032E-03 0,04437895 ! inositol trisphosphate phosphatase activity GO:0046030 8 6 0,000 7,032E-03 0,04430231 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 7,032E-03 0,04422592 ! SMAD protein nuclear translocation GO:0007184 7 6 0,000 7,032E-03 0,0441498 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 9 6 0,000 7,032E-03 0,04407394 ! carbohydrate phosphorylation GO:0046835 7 6 0,000 7,032E-03 0,04399835 ! phosphoinositide 3-kinase binding GO:0043548 6 6 0,000 7,032E-03 0,04392301 ! protein amino acid sulfation GO:0006477 9 6 0,000 7,032E-03 0,04384792 GO:0051923|sulfation, ! diphosphotransferase activity GO:0016778 7 6 0,000 7,032E-03 0,0437731 ! establishment of tissue polarity GO:0007164 8 6 0,000 7,032E-03 0,04369853 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 7,032E-03 0,04362421 ! receptor guanylyl cyclase signaling pathway GO:0007168 6 6 0,000 7,032E-03 0,04355015 ! embryonic camera-type eye development GO:0031076 9 6 0,000 7,032E-03 0,04347633 GO:0048596|embryonic camera-type eye morphogenesis, ! hexokinase activity GO:0004396 7 6 0,000 7,032E-03 0,04340277 ! regulation of mitochondrial membrane permeability GO:0046902 7 6 0,000 7,032E-03 0,04332945 ! neurofilament cytoskeleton organization GO:0060052 6 6 0,000 7,032E-03 0,04325638 ! Notch receptor processing GO:0007220 7 6 0,000 7,032E-03 0,04318356 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 8 6 0,000 7,032E-03 0,04311098 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 7 6 0,000 7,032E-03 0,04303865 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 7,032E-03 0,04296656 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 7,032E-03 0,04289471 ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 6 0,000 7,032E-03 0,0428231 ! neurofilament GO:0005883 7 6 0,000 7,032E-03 0,04275173 ! glial cell fate commitment GO:0021781 7 6 0,000 7,032E-03 0,04268059 ! cytoplasmic dynein complex GO:0005868 7 6 0,000 7,032E-03 0,04260969 ! dynactin complex GO:0005869 7 6 0,000 7,032E-03 0,04253903 ! fibroblast growth factor receptor antagonist activity GO:0030353 7 6 0,000 7,032E-03 0,0424686 GO:0005152|interleukin-1 receptor antagonist activity, ! enoyl-CoA hydratase activity GO:0004300 6 6 0,000 7,032E-03 0,04239841 ! oocyte maturation GO:0001556 6 6 0,000 7,032E-03 0,04232844 ! DNA replication origin binding GO:0003688 6 6 0,000 7,032E-03 0,04225871 ! reflex GO:0060004 10 6 0,000 7,032E-03 0,0421892 ! positive regulation of glycolysis GO:0045821 6 6 0,000 7,032E-03 0,04211993 ! parathyroid gland development GO:0060017 6 6 0,000 7,032E-03 0,04205088 ! anagen GO:0042640 7 6 0,000 7,032E-03 0,04198206 ! protein-cofactor linkage GO:0018065 15 6 0,000 7,032E-03 0,04191346 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 6 6 0,000 7,032E-03 0,04184508 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! protein targeting to ER GO:0045047 7 6 0,000 7,032E-03 0,04177693 GO:0006614|SRP-dependent cotranslational protein targeting to membrane, ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 6 6 0,000 7,032E-03 0,041709 ! skeletal myofibril assembly GO:0014866 6 6 0,000 7,032E-03 0,04164129 ! structural constituent of tooth enamel GO:0030345 7 6 0,000 7,032E-03 0,0415738 ! cysteine metabolic process GO:0006534 7 6 0,000 7,032E-03 0,04150653 ! glycine catabolic process GO:0006546 6 6 0,000 7,032E-03 0,04143948 ! adenohypophysis development GO:0021984 6 6 0,000 7,032E-03 0,04137264 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 6 6 0,000 7,032E-03 0,04130602 ! deoxyribonucleotide biosynthetic process GO:0009263 7 6 0,000 7,032E-03 0,04123961 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 6 0,000 7,032E-03 0,04117341 ! microtubule nucleation GO:0007020 7 6 0,000 7,032E-03 0,04110743 ! proline biosynthetic process GO:0006561 8 6 0,000 7,032E-03 0,04104166 ! tryptophan metabolic process GO:0006568 6 6 0,000 7,032E-03 0,0409761 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 6 6 0,000 7,032E-03 0,04091074 ! thyroid hormone generation GO:0006590 6 6 0,000 7,032E-03 0,0408456 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 7,032E-03 0,04078066 ! retinoid X receptor binding GO:0046965 7 6 0,000 7,032E-03 0,04071593 ! proton-transporting V-type ATPase, V0 domain GO:0033179 6 6 0,000 7,032E-03 0,0406514 ! transforming growth factor beta receptor activity, type I GO:0005025 7 6 0,000 7,032E-03 0,04058708 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 7,032E-03 0,04052296 ! sister chromatid cohesion GO:0007062 6 6 0,000 7,032E-03 0,04045905 ! retinoic acid receptor signaling pathway GO:0048384 9 6 0,000 7,032E-03 0,04039533 ! positive regulation of transporter activity GO:0032411 8 6 0,000 7,032E-03 0,04033182 GO:0032414|positive regulation of ion transmembrane transporter activity, ! cerebral cortex neuron differentiation GO:0021895 7 6 0,000 7,032E-03 0,0402685 ! regulation of fatty acid beta-oxidation GO:0031998 6 6 0,000 7,032E-03 0,04020539 ! p53 binding GO:0002039 6 6 0,000 7,032E-03 0,04014247 ! demethylase activity GO:0032451 6 6 0,000 7,032E-03 0,04007974 ! positive regulation of nitric-oxide synthase activity GO:0051000 6 6 0,000 7,032E-03 0,04001722 ! regulation of platelet activation GO:0010543 7 6 0,000 7,032E-03 0,03995488 ! lipid phosphatase activity GO:0042577 7 6 0,000 7,032E-03 0,03989275 ! lens morphogenesis in camera-type eye GO:0002089 6 6 0,000 7,032E-03 0,0398308 ! guanylate cyclase activator activity GO:0030250 6 6 0,000 7,032E-03 0,03976905 GO:0010853|cyclase activator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 8 6 0,000 7,032E-03 0,03970749 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of exocytosis GO:0045921 6 6 0,000 7,032E-03 0,03964611 ! protein tyrosine kinase activator activity GO:0030296 8 6 0,000 7,032E-03 0,03958493 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 7,032E-03 0,03952394 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of steroid metabolic process GO:0045940 6 6 0,000 7,032E-03 0,03946313 ! LIM domain binding GO:0030274 7 6 0,000 7,032E-03 0,03940251 ! negative regulation of translational initiation GO:0045947 6 6 0,000 7,032E-03 0,03934208 ! positive regulation vascular endothelial growth factor production GO:0010575 6 6 0,000 7,032E-03 0,03928183 ! 5S class rRNA transcription GO:0042791 6 6 0,000 7,032E-03 0,03922177 GO:0042797|tRNA transcription from RNA polymerase III promoter, GO:0000127|transcription factor TFIIIC complex, ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 7,032E-03 0,03916189 ! axon guidance receptor activity GO:0008046 6 6 0,000 7,032E-03 0,03910219 ! zinc ion homeostasis GO:0055069 7 6 0,000 7,032E-03 0,03904267 ! positive regulation of gliogenesis GO:0014015 7 6 0,000 7,032E-03 0,03898334 GO:0045687|positive regulation of glial cell differentiation, ! centrosome duplication GO:0051298 7 6 0,000 7,032E-03 0,03892418 ! protein targeting to lysosome GO:0006622 6 6 0,000 7,032E-03 0,03886521 ! hyaluronan metabolic process GO:0030212 8 6 0,000 7,032E-03 0,03880641 ! protein retention in ER lumen GO:0006621 6 6 0,000 7,032E-03 0,03874779 ! ventricular cardiac muscle cell differentiation GO:0055012 8 6 0,000 7,032E-03 0,03868934 ! circadian sleep/wake cycle GO:0042745 7 6 0,000 7,032E-03 0,03863108 ! dynein binding GO:0045502 6 6 0,000 7,032E-03 0,03857299 ! regulation of dendrite development GO:0050773 6 6 0,000 7,032E-03 0,03851507 ! peptidyl-arginine modification GO:0018195 6 6 0,000 7,032E-03 0,03845732 ! eating behavior GO:0042755 7 6 0,000 7,032E-03 0,03839975 ! protein localization to chromosome GO:0034502 8 6 0,000 7,032E-03 0,03834236 ! glycolipid binding GO:0051861 7 6 0,000 7,032E-03 0,03828513 ! MutLalpha complex binding GO:0032405 8 6 0,000 7,032E-03 0,03822807 ! mast cell activation GO:0045576 6 6 0,000 7,032E-03 0,03817118 ! nucleoside catabolic process GO:0009164 7 6 0,000 7,032E-03 0,03811447 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 7,032E-03 0,03805792 ! molybdopterin cofactor biosynthetic process GO:0032324 15 6 0,000 7,032E-03 0,03800153 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 7,032E-03 0,03794532 ! RNA polymerase II transcription elongation factor activity GO:0016944 6 6 0,000 7,032E-03 0,03788927 ! lipoxygenase activity GO:0016165 6 6 0,000 7,032E-03 0,03783339 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 7,032E-03 0,03777767 ! alpha DNA polymerase:primase complex GO:0005658 16 6 0,000 7,032E-03 0,03772211 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 7,032E-03 0,03766672 ! DNA replication factor C complex GO:0005663 7 6 0,000 7,032E-03 0,03761149 ! DNA replication factor A complex GO:0005662 7 6 0,000 7,032E-03 0,03755642 ! cilium morphogenesis GO:0060271 6 6 0,000 7,032E-03 0,03750151 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 7,032E-03 0,03744677 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 7,032E-03 0,03739218 ! chromatin assembly complex GO:0005678 16 6 0,000 7,032E-03 0,03733775 ! sex chromatin GO:0001739 6 6 0,000 7,032E-03 0,03728348 GO:0000803|sex chromosome, ! morphogenesis of a polarized epithelium GO:0001738 7 6 0,000 7,032E-03 0,03722937 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 7 6 0,000 7,032E-03 0,03717541 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! SAP kinase activity GO:0016909 7 6 0,000 7,032E-03 0,03712161 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 7,032E-03 0,03706797 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 7 6 0,000 7,032E-03 0,03701448 ! positive regulation of pseudopodium assembly GO:0031274 6 6 0,000 7,032E-03 0,03696115 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipoprotein metabolic process GO:0050746 7 6 0,000 7,032E-03 0,03690797 ! phosphatidylserine binding GO:0001786 6 6 0,000 7,032E-03 0,03685494 ! alpha-mannosidase activity GO:0004559 8 6 0,000 7,032E-03 0,03680206 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 6 0,000 7,032E-03 0,03674933 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 7,032E-03 0,03669676 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 11 6 0,000 7,032E-03 0,03664434 GO:0002820|negative regulation of adaptive immune response, ! myeloid dendritic cell activation GO:0001773 8 6 0,000 7,032E-03 0,03659206 GO:0043011|myeloid dendritic cell differentiation, ! immunological synapse GO:0001772 6 6 0,000 7,032E-03 0,03653994 ! leading edge membrane GO:0031256 8 6 0,000 7,032E-03 0,03648796 ! photoreceptor connecting cilium GO:0032391 7 6 0,000 7,032E-03 0,03643613 ! CARD domain binding GO:0050700 6 6 0,000 7,032E-03 0,03638445 ! regulation of muscle cell apoptosis GO:0010660 7 6 0,000 7,032E-03 0,03633291 ! COPII vesicle coat GO:0030127 7 6 0,000 7,032E-03 0,03628152 GO:0012507|ER to Golgi transport vesicle membrane, ! molybdenum ion binding GO:0030151 15 6 0,000 7,032E-03 0,03623028 ! glutathione biosynthetic process GO:0006750 7 6 0,000 7,032E-03 0,03617918 ! positive regulation of erythrocyte differentiation GO:0045648 8 6 0,000 7,032E-03 0,03612822 ! positive regulation of epidermis development GO:0045684 8 6 0,000 7,032E-03 0,03607741 ! proteasome regulator activity GO:0010860 6 6 0,000 7,032E-03 0,03602674 ! ceramidase activity GO:0017040 6 6 0,000 7,032E-03 0,03597621 ! antibiotic transport GO:0042891 7 6 0,000 7,032E-03 0,03592582 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 7,032E-03 0,03587557 ! regulation of T-helper cell differentiation GO:0045622 6 6 0,000 7,032E-03 0,03582547 ! sodium channel regulator activity GO:0017080 6 6 0,000 7,032E-03 0,0357755 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 7,032E-03 0,03572568 ! regulation of protein homodimerization activity GO:0043496 9 6 0,000 7,032E-03 0,03567599 ! response to fluid shear stress GO:0034405 6 6 0,000 7,032E-03 0,03562644 ! lymph node development GO:0048535 6 6 0,000 7,032E-03 0,03557703 ! negative regulation of viral reproduction GO:0048525 7 6 0,000 7,032E-03 0,03552775 ! triglyceride catabolic process GO:0019433 15 6 0,000 7,032E-03 0,03547861 ! positive regulation of fatty acid oxidation GO:0046321 6 6 0,000 7,032E-03 0,03542961 ! ectodermal gut morphogenesis GO:0048567 7 6 0,000 7,032E-03 0,03538074 GO:0007439|ectodermal gut development, ! T cell activation during immune response GO:0002286 6 6 0,000 7,032E-03 0,03533201 ! negative regulation of lipase activity GO:0060192 6 6 0,000 7,032E-03 0,03528341 ! activation of innate immune response GO:0002218 6 6 0,000 7,032E-03 0,03523494 GO:0002758|innate immune response-activating signal transduction, ! regulation of telomere maintenance via telomerase GO:0032210 7 6 0,000 7,032E-03 0,03518661 ! sarcoglycan complex GO:0016012 8 6 0,000 7,032E-03 0,03513841 ! natural killer cell mediated immunity GO:0002228 7 6 0,000 7,032E-03 0,03509034 GO:0042267|natural killer cell mediated cytotoxicity, ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 6 6 0,000 7,032E-03 0,0350424 ! neural plate development GO:0001840 7 6 0,000 7,032E-03 0,03499459 ! regulation of synaptic transmission, GABAergic GO:0032228 15 6 0,000 7,032E-03 0,03494692 ! catecholamine transport GO:0051937 6 6 0,000 7,032E-03 0,03489937 ! ether hydrolase activity GO:0016803 7 6 0,000 7,032E-03 0,03485195 ! FACIT collagen GO:0005593 6 6 0,000 7,032E-03 0,03480466 ! lactate dehydrogenase activity GO:0004457 6 6 0,000 7,032E-03 0,0347575 ! regulation of T cell receptor signaling pathway GO:0050856 7 6 0,000 7,032E-03 0,03471047 ! collagen type IV GO:0005587 6 6 0,000 7,032E-03 0,03466356 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 7,032E-03 0,03461678 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 7 6 0,000 7,032E-03 0,03457013 ! drug metabolic process GO:0017144 6 6 0,000 7,032E-03 0,0345236 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 7,032E-03 0,0344772 ! negative regulation of synaptic transmission GO:0050805 6 6 0,000 7,032E-03 0,03443092 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 7,032E-03 0,03438477 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 7,032E-03 0,03433874 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 6 6 0,000 7,032E-03 0,03429283 ! regulation of microtubule polymerization GO:0031113 6 6 0,000 7,032E-03 0,03424704 ! cellular anion homeostasis GO:0030002 6 6 0,000 7,032E-03 0,03420138 GO:0055081|anion homeostasis, ! regulation of MHC class II biosynthetic process GO:0045346 6 6 0,000 7,032E-03 0,03415584 ! negative regulation of fibroblast proliferation GO:0048147 6 6 0,000 7,032E-03 0,03411042 ! behavioral response to cocaine GO:0048148 9 6 0,000 7,032E-03 0,03406512 ! translation initiation factor binding GO:0031369 6 6 0,000 7,032E-03 0,03401994 ! nucleotide-sugar transport GO:0015780 6 6 0,000 7,032E-03 0,03397488 ! sulfur amino acid transmembrane transporter activity GO:0000099 6 6 0,000 7,032E-03 0,03392994 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 7,032E-03 0,03388512 ! quaternary ammonium group binding GO:0050997 7 6 0,000 7,032E-03 0,03384042 ! actin-dependent ATPase activity GO:0030898 7 6 0,000 7,032E-03 0,03379583 ! reproductive behavior GO:0019098 8 6 0,000 7,032E-03 0,03375136 ! response to growth hormone stimulus GO:0060416 7 6 0,000 7,032E-03 0,03370701 GO:0060396|growth hormone receptor signaling pathway, ! negative regulation of JAK-STAT cascade GO:0046426 8 6 0,000 7,032E-03 0,03366278 ! nucleotide-excision repair, DNA incision GO:0033683 6 6 0,000 7,032E-03 0,03361866 ! negative regulation of cell-cell adhesion GO:0022408 8 6 0,000 7,032E-03 0,03357465 ! positive regulation of cell-cell adhesion GO:0022409 7 6 0,000 7,032E-03 0,03353077 ! induction of positive chemotaxis GO:0050930 7 6 0,000 7,032E-03 0,03348699 ! cohesin complex GO:0008278 6 6 0,000 7,032E-03 0,03344333 ! regulation of collagen biosynthetic process GO:0032965 7 6 0,000 7,032E-03 0,03339979 ! citrate metabolic process GO:0006101 7 6 0,000 7,032E-03 0,03335635 ! myelin sheath GO:0043209 8 6 0,000 7,032E-03 0,03331303 ! phototransduction, visible light GO:0007603 6 6 0,000 7,032E-03 0,03326983 ! opsonization GO:0008228 7 6 0,000 7,032E-03 0,03322673 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 7,032E-03 0,03318375 ! regulation of dopamine metabolic process GO:0042053 8 6 0,000 7,032E-03 0,03314087 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 7 6 0,000 7,032E-03 0,03309811 ! regulation of potassium ion transport GO:0043266 8 6 0,000 7,032E-03 0,03305546 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 7,032E-03 0,03301292 ! chemoattractant activity GO:0042056 6 6 0,000 7,032E-03 0,03297048 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 8 6 0,000 7,032E-03 0,03292816 ! low-density lipoprotein particle remodeling GO:0034374 6 6 0,000 7,032E-03 0,03288594 ! ornithine decarboxylase regulator activity GO:0042979 6 6 0,000 7,032E-03 0,03284384 ! leukocyte degranulation GO:0043299 6 6 0,000 7,032E-03 0,03280184 ! bile acid and bile salt transport GO:0015721 7 6 0,000 7,032E-03 0,03275994 ! mitochondrial genome maintenance GO:0000002 6 6 0,000 7,032E-03 0,03271816 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 6 0,000 7,032E-03 0,03267648 ! DNA topoisomerase activity GO:0003916 6 6 0,000 7,032E-03 0,03263491 ! protein geranylgeranyltransferase activity GO:0004661 7 6 0,000 7,032E-03 0,03259344 ! ceramide biosynthetic process GO:0046513 6 6 0,000 7,032E-03 0,03255208 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 7,032E-03 0,03251082 ! activin receptor activity GO:0017002 7 6 0,000 7,032E-03 0,03246967 ! astrocyte differentiation GO:0048708 6 6 0,000 7,032E-03 0,03242862 ! syncytium formation GO:0006949 6 6 0,000 7,032E-03 0,03238767 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 7,032E-03 0,03234683 ! neutrophil activation GO:0042119 6 6 0,000 7,032E-03 0,03230609 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 7,032E-03 0,03226545 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 7,032E-03 0,03222492 ! positive regulation of activated T cell proliferation GO:0042104 7 6 0,000 7,032E-03 0,03218449 ! positive transcription elongation factor activity GO:0008159 7 6 0,000 7,032E-03 0,03214416 ! NuA4 histone acetyltransferase complex GO:0035267 8 6 0,000 7,032E-03 0,03210392 ! cellular polysaccharide catabolic process GO:0044247 17 6 0,000 7,032E-03 0,03206379 GO:0009251|glucan catabolic process, ! response to salt stress GO:0009651 7 6 0,000 7,032E-03 0,03202376 ! neuron apoptosis GO:0051402 7 6 0,000 7,032E-03 0,03198384 ! folic acid transport GO:0015884 8 6 0,000 7,032E-03 0,031944 ! carnitine transport GO:0015879 6 6 0,000 7,032E-03 0,03190427 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 7,032E-03 0,03186464 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! parturition GO:0007567 7 6 0,000 7,032E-03 0,03182511 ! S-methyltransferase activity GO:0008172 6 6 0,000 7,032E-03 0,03178567 ! phospholipase D activity GO:0004630 6 6 0,000 7,032E-03 0,03174633 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 7,032E-03 0,03170709 ! intercalated disc GO:0014704 8 6 0,000 7,032E-03 0,03166795 ! G2/M transition checkpoint GO:0031576 24 6 0,000 7,032E-03 0,0316289 GO:0031572|G2/M transition DNA damage checkpoint, ! interaction with symbiont GO:0051702 6 6 0,000 7,032E-03 0,03158995 ! IgG binding GO:0019864 6 6 0,000 7,032E-03 0,03155109 ! regulation of T cell cytokine production GO:0002724 6 6 0,000 7,032E-03 0,03151233 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 6 6 0,000 7,032E-03 0,03147366 ! benzodiazepine receptor activity GO:0008503 7 6 0,000 7,032E-03 0,03143509 ! antigen processing and presentation of exogenous antigen GO:0019884 7 6 0,000 7,032E-03 0,03139662 ! regulation of T cell differentiation in the thymus GO:0033081 7 6 0,000 7,032E-03 0,03135823 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 6 6 0,000 7,032E-03 0,03131995 ! regulation of interleukin-4 production GO:0032673 6 6 0,000 7,032E-03 0,03128175 ! dendrite morphogenesis GO:0048813 7 6 0,000 7,032E-03 0,03124365 ! regulation of interleukin-1 production GO:0032652 7 6 0,000 7,032E-03 0,03120564 ! ribosomal large subunit biogenesis GO:0042273 7 6 0,000 7,032E-03 0,03116772 ! regulation of myeloid cell apoptosis GO:0033032 8 6 0,000 7,032E-03 0,0311299 ! nucleosome disassembly GO:0006337 7 6 0,000 7,032E-03 0,03109216 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! general transcriptional repressor activity GO:0016565 7 6 0,000 7,032E-03 0,03105452 ! regulation of mast cell activation GO:0033003 6 6 0,000 7,032E-03 0,03101697 ! tetracycline transporter activity GO:0008493 7 6 0,000 7,032E-03 0,03097951 GO:0042895|antibiotic transporter activity, ! guanylyltransferase activity GO:0070568 7 6 0,000 7,032E-03 0,03094214 ! receptor internalization GO:0031623 8 6 0,000 7,032E-03 0,03090486 ! N-formyl peptide receptor activity GO:0004982 6 6 0,000 7,032E-03 0,03086767 ! coenzyme A biosynthetic process GO:0015937 6 6 0,000 7,032E-03 0,03083057 ! histamine receptor activity GO:0004969 7 6 0,000 7,032E-03 0,03079356 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 6 0,000 7,032E-03 0,03075664 ! pyrimidine nucleotide sugar transmembrane transporter activity GO:0015165 6 6 0,000 7,032E-03 0,0307198 ! protein deubiquitination GO:0016579 6 6 0,000 7,032E-03 0,03068306 ! axonal fasciculation GO:0007413 7 6 0,000 7,032E-03 0,0306464 ! basic amino acid transmembrane transporter activity GO:0015174 6 6 0,000 7,032E-03 0,03060983 ! cytidine deaminase activity GO:0004126 6 6 0,000 7,032E-03 0,03057334 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 7,032E-03 0,03053695 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 7,032E-03 0,03050064 GO:0015991|ATP hydrolysis coupled proton transport, ! alpha-adrenergic receptor activity GO:0004936 9 6 0,000 7,032E-03 0,03046441 ! cytochrome-b5 reductase activity GO:0004128 7 6 0,000 7,032E-03 0,03042827 ! glycine binding GO:0016594 9 6 0,000 7,032E-03 0,03039222 ! apical protein localization GO:0045176 7 6 0,000 7,032E-03 0,03035626 ! ankyrin binding GO:0030506 6 6 0,000 7,032E-03 0,03032037 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 7,032E-03 0,03028458 ! thyroid hormone receptor activity GO:0004887 7 6 0,000 7,032E-03 0,03024886 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 7,032E-03 0,03021323 ! progesterone metabolic process GO:0042448 6 6 0,000 7,032E-03 0,03017769 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 7 6 0,000 7,032E-03 0,03014223 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 7,032E-03 0,03010685 ! type II transforming growth factor beta receptor binding GO:0005114 6 6 0,000 7,032E-03 0,03007155 ! ATP catabolic process GO:0006200 6 6 0,000 7,032E-03 0,03003634 ! CoA carboxylase activity GO:0016421 6 6 0,000 7,032E-03 0,03000121 ! determination of adult lifespan GO:0008340 6 6 0,000 7,032E-03 0,02996616 ! S-acyltransferase activity GO:0016417 6 6 0,000 7,032E-03 0,0299312 ! somatic stem cell maintenance GO:0035019 6 6 0,000 7,032E-03 0,02989631 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 7,032E-03 0,02986151 ! IkappaB kinase complex GO:0008385 7 6 0,000 7,032E-03 0,02982679 ! nucleobase transmembrane transporter activity GO:0015205 7 6 0,000 7,032E-03 0,02979214 ! store-operated calcium channel activity GO:0015279 6 6 0,000 7,032E-03 0,02975758 ! alkaline phosphatase activity GO:0004035 7 6 0,000 7,032E-03 0,0297231 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 6 0,000 7,032E-03 0,0296887 ! unconventional myosin complex GO:0016461 8 6 0,000 7,032E-03 0,02965438 ! tRNA transcription GO:0009304 7 7 0,000 8,199E-03 0,03453745 ! respiratory burst GO:0045730 7 7 0,000 8,199E-03 0,03449762 ! telencephalon cell migration GO:0022029 8 7 0,000 8,199E-03 0,03445787 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 8,199E-03 0,03441822 ! cation:chloride symporter activity GO:0015377 8 7 0,000 8,199E-03 0,03437866 ! RNA cap binding GO:0000339 8 7 0,000 8,199E-03 0,03433919 ! generation of neurons in the forebrain GO:0021872 8 7 0,000 8,199E-03 0,03429981 ! ephrin receptor binding GO:0046875 9 7 0,000 8,199E-03 0,03426052 ! male meiosis I GO:0007141 7 7 0,000 8,199E-03 0,03422132 ! synapsis GO:0007129 7 7 0,000 8,199E-03 0,03418221 GO:0070192|chromosome organization involved in meiosis, ! insulin receptor substrate binding GO:0043560 10 7 0,000 8,199E-03 0,03414319 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 8,199E-03 0,03410426 ! type I transforming growth factor beta receptor binding GO:0034713 8 7 0,000 8,199E-03 0,03406542 ! signal peptide processing GO:0006465 7 7 0,000 8,199E-03 0,03402666 ! regulation of cardiac muscle cell proliferation GO:0060043 8 7 0,000 8,199E-03 0,03398799 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 8,199E-03 0,03394942 ! macrophage chemotaxis GO:0048246 7 7 0,000 8,199E-03 0,03391092 ! Golgi cisterna membrane GO:0032580 7 7 0,000 8,199E-03 0,03387252 ! neurofilament cytoskeleton GO:0060053 8 7 0,000 8,199E-03 0,0338342 ! positive regulation of receptor-mediated endocytosis GO:0048260 7 7 0,000 8,199E-03 0,03379597 ! smoothened signaling pathway GO:0007224 8 7 0,000 8,199E-03 0,03375783 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 8,199E-03 0,03371977 ! oxidoreductase activity, oxidizing metal ions GO:0016722 7 7 0,000 8,199E-03 0,0336818 ! Arp2/3 protein complex GO:0005885 8 7 0,000 8,199E-03 0,03364391 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 7 7 0,000 8,199E-03 0,03360611 ! ATPase binding GO:0051117 8 7 0,000 8,199E-03 0,03356839 ! positive regulation of isotype switching GO:0045830 7 7 0,000 8,199E-03 0,03353076 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 8,199E-03 0,03349321 ! positive regulation of gene expression, epigenetic GO:0045815 7 7 0,000 8,199E-03 0,03345574 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 7 0,000 8,199E-03 0,03341836 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 8,199E-03 0,03338107 ! thymic T cell selection GO:0045061 16 7 0,000 8,199E-03 0,03334385 ! transepithelial chloride transport GO:0030321 7 7 0,000 8,199E-03 0,03330672 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 8,199E-03 0,03326967 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 7 7 0,000 8,199E-03 0,03323271 ! negative regulation of survival gene product expression GO:0008634 9 7 0,000 8,199E-03 0,03319582 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 8,199E-03 0,03315902 ! melanocyte differentiation GO:0030318 8 7 0,000 8,199E-03 0,0331223 ! malate dehydrogenase activity GO:0016615 8 7 0,000 8,199E-03 0,03308566 ! mitochondrial respiratory chain complex assembly GO:0033108 7 7 0,000 8,199E-03 0,0330491 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! DNA secondary structure binding GO:0000217 16 7 0,000 8,199E-03 0,03301262 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 8 7 0,000 8,199E-03 0,03297622 ! regulation of peptidyl-serine phosphorylation GO:0033135 7 7 0,000 8,199E-03 0,03293991 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 8,199E-03 0,03290367 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 8,199E-03 0,03286751 GO:0021940|positive regulation of granule cell precursor proliferation, ! V(D)J recombination GO:0033151 8 7 0,000 8,199E-03 0,03283143 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 8,199E-03 0,03279543 ! vascular endothelial growth factor receptor activity GO:0005021 12 7 0,000 8,199E-03 0,03275951 ! central nervous system neuron axonogenesis GO:0021955 8 7 0,000 8,199E-03 0,03272367 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 8,199E-03 0,03268791 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! response to tumor necrosis factor GO:0034612 8 7 0,000 8,199E-03 0,03265222 ! peptidoglycan metabolic process GO:0000270 9 7 0,000 8,199E-03 0,03261661 GO:0009253|peptidoglycan catabolic process, ! response to ATP GO:0033198 7 7 0,000 8,199E-03 0,03258108 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 8 7 0,000 8,199E-03 0,03254563 GO:0048500|signal recognition particle, ! stereocilium GO:0032420 10 7 0,000 8,199E-03 0,03251026 ! paraxial mesoderm morphogenesis GO:0048340 9 7 0,000 8,199E-03 0,03247496 ! melanosome organization GO:0032438 7 7 0,000 8,199E-03 0,03243973 ! mesodermal cell differentiation GO:0048333 9 7 0,000 8,199E-03 0,03240459 GO:0001710|mesodermal cell fate commitment, ! positive regulation of neuroblast proliferation GO:0002052 7 7 0,000 8,199E-03 0,03236952 ! Rac protein signal transduction GO:0016601 7 7 0,000 8,199E-03 0,03233452 ! chondrocyte differentiation GO:0002062 7 7 0,000 8,199E-03 0,03229961 ! guanylate cyclase regulator activity GO:0030249 7 7 0,000 8,199E-03 0,03226476 GO:0010851|cyclase regulator activity, ! intestinal cholesterol absorption GO:0030299 9 7 0,000 8,199E-03 0,03222999 ! negative regulation of specific transcription from RNA polymerase II promoter GO:0010553 8 7 0,000 8,199E-03 0,0321953 ! determination of anterior/posterior axis, embryo GO:0008595 10 7 0,000 8,199E-03 0,03216068 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 8 7 0,000 8,199E-03 0,03212614 ! regulation of vascular endothelial growth factor production GO:0010574 7 7 0,000 8,199E-03 0,03209167 ! Schwann cell differentiation GO:0014037 8 7 0,000 8,199E-03 0,03205727 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 9 7 0,000 8,199E-03 0,03202295 ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 8,199E-03 0,0319887 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 8,199E-03 0,03195452 ! vinculin binding GO:0017166 9 7 0,000 8,199E-03 0,03192042 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 8,199E-03 0,03188639 ! regulation of collagen metabolic process GO:0010712 8 7 0,000 8,199E-03 0,03185243 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 8,199E-03 0,03181855 ! negative regulation of gliogenesis GO:0014014 8 7 0,000 8,199E-03 0,03178473 GO:0045686|negative regulation of glial cell differentiation, ! translation termination factor activity GO:0008079 7 7 0,000 8,199E-03 0,03175099 GO:0003747|translation release factor activity, ! purine base biosynthetic process GO:0009113 8 7 0,000 8,199E-03 0,03171732 ! cardiac muscle cell development GO:0055013 8 7 0,000 8,199E-03 0,03168372 ! fibrinolysis GO:0042730 9 7 0,000 8,199E-03 0,0316502 ! response to tropane GO:0014073 10 7 0,000 8,199E-03 0,03161674 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 7 7 0,000 8,199E-03 0,03158335 GO:0051904|pigment granule transport, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 8 7 0,000 8,199E-03 0,03155004 ! glycosylceramide metabolic process GO:0006677 7 7 0,000 8,199E-03 0,03151679 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 7 7 0,000 8,199E-03 0,03148362 ! laminin-1 complex GO:0005606 7 7 0,000 8,199E-03 0,03145051 GO:0043256|laminin complex, ! regulation of chondrocyte differentiation GO:0032330 8 7 0,000 8,199E-03 0,03141747 ! positive regulation of immunoglobulin mediated immune response GO:0002891 7 7 0,000 8,199E-03 0,03138451 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of lipid transport GO:0032370 8 7 0,000 8,199E-03 0,03135161 ! regulation of cell division GO:0051302 7 7 0,000 8,199E-03 0,03131878 ! holo TFIIH complex GO:0005675 7 7 0,000 8,199E-03 0,03128602 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 7 0,000 8,199E-03 0,03125333 ! chitinase activity GO:0004568 7 7 0,000 8,199E-03 0,0312207 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 8 7 0,000 8,199E-03 0,03118815 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! U12-type spliceosomal complex GO:0005689 8 7 0,000 8,199E-03 0,03115566 ! regulation of respiratory burst GO:0060263 8 7 0,000 8,199E-03 0,03112324 ! prophase GO:0051324 8 7 0,000 8,199E-03 0,03109089 ! peptidyl-histidine modification GO:0018202 8 7 0,000 8,199E-03 0,0310586 ! centriolar satellite GO:0034451 10 7 0,000 8,199E-03 0,03102638 ! BBSome GO:0034464 7 7 0,000 8,199E-03 0,03099423 ! glycerophosphodiester phosphodiesterase activity GO:0008889 7 7 0,000 8,199E-03 0,03096215 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 8,199E-03 0,03093013 ! negative regulation of lymphocyte differentiation GO:0045620 8 7 0,000 8,199E-03 0,03089818 ! negative regulation of transmission of nerve impulse GO:0051970 7 7 0,000 8,199E-03 0,03086629 ! regulation of synaptic transmission, glutamatergic GO:0051966 8 7 0,000 8,199E-03 0,03083447 ! regulation of synaptogenesis GO:0051963 7 7 0,000 8,199E-03 0,03080271 ! serine family amino acid catabolic process GO:0009071 7 7 0,000 8,199E-03 0,03077102 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 8,199E-03 0,0307394 ! glycolipid catabolic process GO:0019377 7 7 0,000 8,199E-03 0,03070784 GO:0046479|glycosphingolipid catabolic process, ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 8 7 0,000 8,199E-03 0,03067634 ! circadian behavior GO:0048512 9 7 0,000 8,199E-03 0,03064491 ! dorsal/ventral axis specification GO:0009950 7 7 0,000 8,199E-03 0,03061355 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 7 0,000 8,199E-03 0,03058224 ! striatum development GO:0021756 7 7 0,000 8,199E-03 0,03055101 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 8 7 0,000 8,199E-03 0,03051983 ! triglyceride biosynthetic process GO:0019432 7 7 0,000 8,199E-03 0,03048872 ! cerebellar Purkinje cell layer development GO:0021680 7 7 0,000 8,199E-03 0,03045767 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 8,199E-03 0,03042669 ! dystroglycan complex GO:0016011 9 7 0,000 8,199E-03 0,03039577 ! negative regulation of calcium ion transport GO:0051926 7 7 0,000 8,199E-03 0,03036491 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 7 0,000 8,199E-03 0,03033411 ! peroxiredoxin activity GO:0051920 7 7 0,000 8,199E-03 0,03030338 ! muscle adaptation GO:0043500 7 7 0,000 8,199E-03 0,03027271 ! regulation of muscle adaptation GO:0043502 7 7 0,000 8,199E-03 0,0302421 ! diacylglycerol metabolic process GO:0046339 7 7 0,000 8,199E-03 0,03021155 ! lysogeny GO:0030069 7 7 0,000 8,199E-03 0,03018106 GO:0019047|provirus integration, ! protein insertion into membrane GO:0051205 7 7 0,000 8,199E-03 0,03015064 ! sequestering of metal ion GO:0051238 9 7 0,000 8,199E-03 0,03012028 ! membrane attack complex GO:0005579 7 7 0,000 8,199E-03 0,03008997 ! fibrinogen complex GO:0005577 7 7 0,000 8,199E-03 0,03005973 ! metallo-sulfur cluster assembly GO:0031163 9 7 0,000 8,199E-03 0,03002955 GO:0016226|iron-sulfur cluster assembly, ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 7 0,000 8,199E-03 0,02999943 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 7 0,000 8,199E-03 0,02996937 ! GABA receptor binding GO:0050811 8 7 0,000 8,199E-03 0,02993937 ! sheet-forming collagen GO:0030935 7 7 0,000 8,199E-03 0,02990943 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 8 7 0,000 8,199E-03 0,02987956 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 8 7 0,000 8,199E-03 0,02984974 ! sphingomyelin phosphodiesterase activity GO:0004767 9 7 0,000 8,199E-03 0,02981997 ! regulation of epithelial cell differentiation GO:0030856 7 7 0,000 8,199E-03 0,02979027 ! 7S RNA binding GO:0008312 8 7 0,000 8,199E-03 0,02976063 ! positive regulation of lipid catabolic process GO:0050996 7 7 0,000 8,199E-03 0,02973105 ! protein phosphorylated amino acid binding GO:0045309 9 7 0,000 8,199E-03 0,02970152 ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 8 7 0,000 8,199E-03 0,02967206 ! regulation of long-term neuronal synaptic plasticity GO:0048169 17 7 0,000 8,199E-03 0,02964265 ! Golgi to endosome transport GO:0006895 8 7 0,000 8,199E-03 0,0296133 ! glucocorticoid receptor signaling pathway GO:0042921 7 7 0,000 8,199E-03 0,02958401 GO:0031958|corticosteroid receptor signaling pathway, ! succinate metabolic process GO:0006105 7 7 0,000 8,199E-03 0,02955478 ! fibril GO:0043205 7 7 0,000 8,199E-03 0,0295256 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 8,199E-03 0,02949648 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 8,199E-03 0,02946742 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 7 0,000 8,199E-03 0,02943842 ! sensory perception of bitter taste GO:0050913 7 7 0,000 8,199E-03 0,02940947 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 8,199E-03 0,02938058 ! posttranscriptional gene silencing by RNA GO:0035194 9 7 0,000 8,199E-03 0,02935175 GO:0016441|posttranscriptional gene silencing, ! cell division site part GO:0032155 9 7 0,000 8,199E-03 0,02932298 GO:0032153|cell division site, ! laminin binding GO:0043236 7 7 0,000 8,199E-03 0,02929426 ! equilibrioception GO:0050957 10 7 0,000 8,199E-03 0,02926559 ! G-protein coupled receptor kinase activity GO:0004703 9 7 0,000 8,199E-03 0,02923698 ! titin binding GO:0031432 7 7 0,000 8,199E-03 0,02920843 ! chemosensory behavior GO:0007635 9 7 0,000 8,199E-03 0,02917994 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 8,199E-03 0,0291515 GO:0032107|regulation of response to nutrient levels, ! plasma lipoprotein particle assembly GO:0034377 7 7 0,000 8,199E-03 0,02912311 ! cobalamin binding GO:0031419 7 7 0,000 8,199E-03 0,02909478 ! sodium:phosphate symporter activity GO:0005436 8 7 0,000 8,199E-03 0,02906651 ! response to axon injury GO:0048678 9 7 0,000 8,199E-03 0,02903829 ! regulation of activin receptor signaling pathway GO:0032925 7 7 0,000 8,199E-03 0,02901012 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 8,199E-03 0,02898201 ! F-actin capping protein complex GO:0008290 8 7 0,000 8,199E-03 0,02895395 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 8,199E-03 0,02892595 ! cGMP-mediated signaling GO:0019934 8 7 0,000 8,199E-03 0,028898 ! nerve growth factor receptor signaling pathway GO:0048011 8 7 0,000 8,199E-03 0,02887011 ! cAMP-dependent protein kinase activity GO:0004691 7 7 0,000 8,199E-03 0,02884227 ! senescence GO:0010149 8 7 0,000 8,199E-03 0,02881448 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 10 7 0,000 8,199E-03 0,02878675 ! nuclear localization sequence binding GO:0008139 8 7 0,000 8,199E-03 0,02875907 ! galactose metabolic process GO:0006012 8 7 0,000 8,199E-03 0,02873145 ! vesicle fusion GO:0006906 8 7 0,000 8,199E-03 0,02870387 ! maintenance of protein location in nucleus GO:0051457 7 7 0,000 8,199E-03 0,02867635 ! intracellular pH reduction GO:0051452 7 7 0,000 8,199E-03 0,02864888 ! glycerol ether catabolic process GO:0044269 16 7 0,000 8,199E-03 0,02862147 GO:0046461|neutral lipid catabolic process, GO:0046464|acylglycerol catabolic process, ! neurotransmitter catabolic process GO:0042135 9 7 0,000 8,199E-03 0,02859411 ! ruffle organization GO:0031529 9 7 0,000 8,199E-03 0,0285668 ! nucleoside transport GO:0015858 8 7 0,000 8,199E-03 0,02853954 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 8,199E-03 0,02851233 ! inclusion body GO:0016234 7 7 0,000 8,199E-03 0,02848518 ! Cajal body GO:0015030 7 7 0,000 8,199E-03 0,02845807 ! H4/H2A histone acetyltransferase complex GO:0043189 9 7 0,000 8,199E-03 0,02843102 ! rRNA modification GO:0000154 7 7 0,000 8,199E-03 0,02840402 ! PcG protein complex GO:0031519 7 7 0,000 8,199E-03 0,02837707 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 8,199E-03 0,02835018 ! NAD-dependent protein deacetylase activity GO:0034979 7 7 0,000 8,199E-03 0,02832333 GO:0017136|NAD-dependent histone deacetylase activity, ! apolipoprotein binding GO:0034185 9 7 0,000 8,199E-03 0,02829653 ! G1 DNA damage checkpoint GO:0031571 7 7 0,000 8,199E-03 0,02826979 ! segment specification GO:0007379 9 7 0,000 8,199E-03 0,02824309 ! pronucleus GO:0045120 25 7 0,000 8,199E-03 0,02821645 ! bile acid:sodium symporter activity GO:0008508 9 7 0,000 8,199E-03 0,02818985 ! Rac GTPase activator activity GO:0030675 9 7 0,000 8,199E-03 0,02816331 ! preribosome GO:0030684 7 7 0,000 8,199E-03 0,02813682 ! DNA topological change GO:0006265 7 7 0,000 8,199E-03 0,02811037 ! DNA ligation GO:0006266 8 7 0,000 8,199E-03 0,02808398 ! hair follicle maturation GO:0048820 8 7 0,000 8,199E-03 0,02805763 ! renal water homeostasis GO:0003091 7 7 0,000 8,199E-03 0,02803134 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 8,199E-03 0,02800509 ! positive regulation of interleukin-6 production GO:0032755 7 7 0,000 8,199E-03 0,02797889 ! interleukin-1 receptor activity GO:0004908 8 7 0,000 8,199E-03 0,02795274 ! positive regulation of tumor necrosis factor production GO:0032760 7 7 0,000 8,199E-03 0,02792664 ! positive regulation of monooxygenase activity GO:0032770 7 7 0,000 8,199E-03 0,02790059 ! inositol trisphosphate 3-kinase activity GO:0008440 8 7 0,000 8,199E-03 0,02787459 ! phosphofructokinase activity GO:0008443 7 7 0,000 8,199E-03 0,02784864 ! gap junction channel activity GO:0005243 8 7 0,000 8,199E-03 0,02782273 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 10 7 0,000 8,199E-03 0,02779687 ! histone methylation GO:0016571 7 7 0,000 8,199E-03 0,02777106 ! positive regulation of interferon-gamma production GO:0032729 7 7 0,000 8,199E-03 0,0277453 ! negative regulation of tumor necrosis factor production GO:0032720 9 7 0,000 8,199E-03 0,02771959 ! mitochondrion morphogenesis GO:0070584 9 7 0,000 8,199E-03 0,02769392 ! muscle cell proliferation GO:0033002 8 7 0,000 8,199E-03 0,0276683 ! transcription termination GO:0006353 9 7 0,000 8,199E-03 0,02764273 ! sodium:amino acid symporter activity GO:0005283 7 7 0,000 8,199E-03 0,02761721 ! cytidylyltransferase activity GO:0070567 8 7 0,000 8,199E-03 0,02759173 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 8,199E-03 0,0275663 ! ATP-dependent peptidase activity GO:0004176 7 7 0,000 8,199E-03 0,02754092 ! salivary gland development GO:0007431 7 7 0,000 8,199E-03 0,02751558 ! glucosidase activity GO:0015926 8 7 0,000 8,199E-03 0,02749029 ! NuRD complex GO:0016581 8 7 0,000 8,199E-03 0,02746505 ! negative regulation of nuclear division GO:0051784 7 7 0,000 8,199E-03 0,02743985 GO:0045839|negative regulation of mitosis, ! ATP-gated cation channel activity GO:0004931 9 7 0,000 8,199E-03 0,0274147 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 7 7 0,000 8,199E-03 0,02738959 ! response to redox state GO:0051775 8 7 0,000 8,199E-03 0,02736453 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 8,199E-03 0,02733952 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 8,199E-03 0,02731455 ! procollagen-proline dioxygenase activity GO:0019798 7 7 0,000 8,199E-03 0,02728963 ! actin monomer binding GO:0003785 7 7 0,000 8,199E-03 0,02726475 ! protein prenyltransferase activity GO:0008318 8 7 0,000 8,199E-03 0,02723992 ! endosome to lysosome transport GO:0008333 7 7 0,000 8,199E-03 0,02721514 ! regulation of Rac protein signal transduction GO:0035020 17 7 0,000 8,199E-03 0,0271904 ! germ cell migration GO:0008354 7 7 0,000 8,199E-03 0,0271657 ! fibroblast growth factor receptor binding GO:0005104 8 7 0,000 8,199E-03 0,02714105 ! negative regulation of organic acid transport GO:0032891 8 7 0,000 8,199E-03 0,02711644 ! CoA-ligase activity GO:0016405 8 7 0,000 8,199E-03 0,02709188 ! positive regulation of NF-kappaB import into nucleus GO:0042346 8 7 0,000 8,199E-03 0,02706736 ! interferon-alpha/beta receptor binding GO:0005132 7 7 0,000 8,199E-03 0,02704289 ! embryonic heart tube development GO:0035050 8 7 0,000 8,199E-03 0,02701846 ! dihydropyridine-sensitive calcium channel activity GO:0015270 10 7 0,000 8,199E-03 0,02699407 ! kainate selective glutamate receptor activity GO:0015277 8 7 0,000 8,199E-03 0,02696973 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 8,199E-03 0,02694544 ! amiloride-sensitive sodium channel activity GO:0015280 7 7 0,000 8,199E-03 0,02692118 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 8,199E-03 0,02689697 ! adenylate kinase activity GO:0004017 8 7 0,000 8,199E-03 0,02687281 ! negative regulation of immune effector process GO:0002698 13 7 0,000 8,199E-03 0,02684868 ! C-X-C chemokine receptor activity GO:0016494 7 7 0,000 8,199E-03 0,02682461 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 7 7 0,000 8,199E-03 0,02680057 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 10 8 0,000 9,365E-03 0,03058465 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 9 8 0,000 9,365E-03 0,03055729 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 8 0,000 9,365E-03 0,03052999 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 9,365E-03 0,03050273 ! regulation of cellular amine metabolic process GO:0033238 10 8 0,000 9,365E-03 0,03047552 ! proteasome regulatory particle GO:0005838 8 8 0,000 9,365E-03 0,03044836 ! SMAD protein complex assembly GO:0007183 10 8 0,000 9,365E-03 0,03042124 ! regulation of smooth muscle cell migration GO:0014910 11 8 0,000 9,365E-03 0,03039418 ! protein self-association GO:0043621 8 8 0,000 9,365E-03 0,03036716 ! glycine hydroxymethyltransferase activity GO:0004372 9 8 0,000 9,365E-03 0,03034019 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 8 0,000 9,365E-03 0,03031327 ! neurotransmitter uptake GO:0001504 8 8 0,000 9,365E-03 0,0302864 ! regulation of activated T cell proliferation GO:0046006 9 8 0,000 9,365E-03 0,03025957 ! guanylate cyclase activity GO:0004383 9 8 0,000 9,365E-03 0,03023279 ! troponin complex GO:0005861 8 8 0,000 9,365E-03 0,03020606 ! eukaryotic translation initiation factor 3 complex GO:0005852 8 8 0,000 9,365E-03 0,03017938 ! tachykinin receptor signaling pathway GO:0007217 8 8 0,000 9,365E-03 0,03015274 ! keratinocyte proliferation GO:0043616 9 8 0,000 9,365E-03 0,03012615 ! negative regulation of muscle cell differentiation GO:0051148 10 8 0,000 9,365E-03 0,03009961 ! microtubule bundle formation GO:0001578 8 8 0,000 9,365E-03 0,03007311 ! middle ear morphogenesis GO:0042474 10 8 0,000 9,365E-03 0,03004666 ! ganglioside metabolic process GO:0001573 8 8 0,000 9,365E-03 0,03002026 ! regulation of mesenchymal cell proliferation GO:0010464 9 8 0,000 9,365E-03 0,0299939 GO:0002053|positive regulation of mesenchymal cell proliferation, ! ovulation from ovarian follicle GO:0001542 8 8 0,000 9,365E-03 0,02996759 ! ciliary or flagellar motility GO:0001539 8 8 0,000 9,365E-03 0,02994133 ! pathogenesis GO:0009405 8 8 0,000 9,365E-03 0,02991511 ! pH reduction GO:0045851 9 8 0,000 9,365E-03 0,02988894 ! small protein activating enzyme activity GO:0008641 10 8 0,000 9,365E-03 0,02986281 ! ribonucleoside triphosphate catabolic process GO:0009203 8 8 0,000 9,365E-03 0,02983673 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 9,365E-03 0,02981069 ! hemoglobin metabolic process GO:0020027 8 8 0,000 9,365E-03 0,0297847 ! regulation of S phase of mitotic cell cycle GO:0007090 8 8 0,000 9,365E-03 0,02975876 ! arginine catabolic process GO:0006527 9 8 0,000 9,365E-03 0,02973286 ! T-tubule GO:0030315 9 8 0,000 9,365E-03 0,029707 ! regulation of defense response to virus by virus GO:0050690 17 8 0,000 9,365E-03 0,02968119 ! histidine catabolic process GO:0006548 8 8 0,000 9,365E-03 0,02965543 GO:0009077|histidine family amino acid catabolic process, ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 9,365E-03 0,02962971 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 8 0,000 9,365E-03 0,02960403 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 10 8 0,000 9,365E-03 0,0295784 ! proline metabolic process GO:0006560 10 8 0,000 9,365E-03 0,02955282 ! L-serine metabolic process GO:0006563 9 8 0,000 9,365E-03 0,02952727 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 8 8 0,000 9,365E-03 0,02950177 ! melanosome membrane GO:0033162 9 8 0,000 9,365E-03 0,02947632 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 9,365E-03 0,02945091 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 8 8 0,000 9,365E-03 0,02942554 ! pericentriolar material GO:0000242 9 8 0,000 9,365E-03 0,02940022 ! reverse cholesterol transport GO:0043691 8 8 0,000 9,365E-03 0,02937494 ! tumor necrosis factor receptor activity GO:0005031 8 8 0,000 9,365E-03 0,0293497 ! melanin metabolic process GO:0006582 10 8 0,000 9,365E-03 0,02932451 ! proton-transporting V-type ATPase, V1 domain GO:0033180 8 8 0,000 9,365E-03 0,02929936 ! phasic smooth muscle contraction GO:0014821 9 8 0,000 9,365E-03 0,02927425 ! Golgi lumen GO:0005796 8 8 0,000 9,365E-03 0,02924919 ! positive regulation of endothelial cell migration GO:0010595 9 8 0,000 9,365E-03 0,02922417 ! regulation of Cdc42 protein signal transduction GO:0032489 9 8 0,000 9,365E-03 0,02919919 GO:0043088|regulation of Cdc42 GTPase activity, ! methyltransferase complex GO:0034708 8 8 0,000 9,365E-03 0,02917426 GO:0035097|histone methyltransferase complex, ! paraxial mesoderm development GO:0048339 10 8 0,000 9,365E-03 0,02914936 ! stereocilium bundle GO:0032421 11 8 0,000 9,365E-03 0,02912451 ! forebrain cell migration GO:0021885 9 8 0,000 9,365E-03 0,02909971 ! peptidyl-threonine phosphorylation GO:0018107 11 8 0,000 9,365E-03 0,02907494 ! osteoblast development GO:0002076 11 8 0,000 9,365E-03 0,02905022 ! retinoic acid metabolic process GO:0042573 8 8 0,000 9,365E-03 0,02902554 ! retinol metabolic process GO:0042572 8 8 0,000 9,365E-03 0,0290009 ! negative regulation of muscle contraction GO:0045932 10 8 0,000 9,365E-03 0,0289763 ! structural constituent of epidermis GO:0030280 9 8 0,000 9,365E-03 0,02895174 ! clathrin binding GO:0030276 10 8 0,000 9,365E-03 0,02892723 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 9 8 0,000 9,365E-03 0,02890275 ! chondroitin sulfate biosynthetic process GO:0030206 9 8 0,000 9,365E-03 0,02887832 GO:0030204|chondroitin sulfate metabolic process, ! sodium:dicarboxylate symporter activity GO:0017153 9 8 0,000 9,365E-03 0,02885393 ! motor axon guidance GO:0008045 8 8 0,000 9,365E-03 0,02882958 ! protein targeting to vacuole GO:0006623 8 8 0,000 9,365E-03 0,02880527 ! negative regulation of axonogenesis GO:0050771 12 8 0,000 9,365E-03 0,02878101 ! peptidyl-asparagine modification GO:0018196 8 8 0,000 9,365E-03 0,02875678 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! melanosome localization GO:0032400 8 8 0,000 9,365E-03 0,02873259 GO:0032401|establishment of melanosome localization, GO:0051875|pigment granule localization, GO:0051905|establishment of pigment granule localization, ! mismatch repair complex binding GO:0032404 10 8 0,000 9,365E-03 0,02870845 ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 9,365E-03 0,02868434 ! protein-lipid complex assembly GO:0065005 8 8 0,000 9,365E-03 0,02866028 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 9 8 0,000 9,365E-03 0,02863626 ! phosphoinositide 3-kinase cascade GO:0014065 8 8 0,000 9,365E-03 0,02861227 ! regulation of dopamine secretion GO:0014059 9 8 0,000 9,365E-03 0,02858833 ! regulation of protein kinase B signaling cascade GO:0051896 9 8 0,000 9,365E-03 0,02856443 ! cranial nerve morphogenesis GO:0021602 9 8 0,000 9,365E-03 0,02854056 ! subpallium development GO:0021544 8 8 0,000 9,365E-03 0,02851674 ! icosanoid secretion GO:0032309 10 8 0,000 9,365E-03 0,02849296 GO:0050482|arachidonic acid secretion, ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 9,365E-03 0,02846921 ! regulation of DNA replication initiation GO:0030174 8 8 0,000 9,365E-03 0,02844551 ! negative regulation of cytokine secretion GO:0050710 10 8 0,000 9,365E-03 0,02842184 ! dolichyl-diphosphooligosaccharide-protein glycotransferase activity GO:0004579 8 8 0,000 9,365E-03 0,02839822 ! exodeoxyribonuclease activity GO:0004529 18 8 0,000 9,365E-03 0,02837463 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! ER to Golgi transport vesicle GO:0030134 9 8 0,000 9,365E-03 0,02835108 ! nucleotide diphosphatase activity GO:0004551 9 8 0,000 9,365E-03 0,02832757 ! regulation of myoblast differentiation GO:0045661 9 8 0,000 9,365E-03 0,0283041 ! ubiquinone metabolic process GO:0006743 9 8 0,000 9,365E-03 0,02828067 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! neuromuscular process controlling posture GO:0050884 8 8 0,000 9,365E-03 0,02825728 ! multicellular organismal water homeostasis GO:0050891 8 8 0,000 9,365E-03 0,02823393 ! branched chain family amino acid catabolic process GO:0009083 9 8 0,000 9,365E-03 0,02821061 ! Wnt receptor activity GO:0042813 11 8 0,000 9,365E-03 0,02818734 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 9,365E-03 0,0281641 ! leukocyte mediated cytotoxicity GO:0001909 10 8 0,000 9,365E-03 0,0281409 ! detection of calcium ion GO:0005513 9 8 0,000 9,365E-03 0,02811774 ! negative regulation of glucose import GO:0046325 9 8 0,000 9,365E-03 0,02809462 ! blastocyst growth GO:0001832 8 8 0,000 9,365E-03 0,02807153 ! regulation of fibrinolysis GO:0051917 8 8 0,000 9,365E-03 0,02804848 ! negative regulation of telomere maintenance GO:0032205 9 8 0,000 9,365E-03 0,02802548 ! cerebellar cortex formation GO:0021697 9 8 0,000 9,365E-03 0,0280025 ! complement binding GO:0001848 11 8 0,000 9,365E-03 0,02797957 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 8 0,000 9,365E-03 0,02795667 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 8 0,000 9,365E-03 0,02793381 ! amino sugar catabolic process GO:0046348 8 8 0,000 9,365E-03 0,02791099 GO:0006043|glucosamine catabolic process, ! FK506 binding GO:0005528 9 8 0,000 9,365E-03 0,02788821 GO:0005527|macrolide binding, ! dipeptidase activity GO:0016805 8 8 0,000 9,365E-03 0,02786546 ! positive regulation of amine transport GO:0051954 9 8 0,000 9,365E-03 0,02784275 ! release of sequestered calcium ion into cytosol GO:0051209 13 8 0,000 9,365E-03 0,02782008 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, ! B cell receptor signaling pathway GO:0050853 13 8 0,000 9,365E-03 0,02779744 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 9,365E-03 0,02777484 ! Golgi transport complex GO:0017119 8 8 0,000 9,365E-03 0,02775228 ! GDP binding GO:0019003 9 8 0,000 9,365E-03 0,02772975 ! positive regulation of glucose metabolic process GO:0010907 8 8 0,000 9,365E-03 0,02770726 ! prostate gland development GO:0030850 17 8 0,000 9,365E-03 0,02768481 ! DNA synthesis during DNA repair GO:0000731 19 8 0,000 9,365E-03 0,02766239 ! nitric-oxide synthase binding GO:0050998 9 8 0,000 9,365E-03 0,02764001 ! phosphate transport GO:0006817 9 8 0,000 9,365E-03 0,02761767 ! cellular copper ion homeostasis GO:0006878 8 8 0,000 9,365E-03 0,02759536 ! oligopeptide transport GO:0006857 8 8 0,000 9,365E-03 0,02757309 GO:0015198|oligopeptide transporter activity, ! pigment cell differentiation GO:0050931 9 8 0,000 9,365E-03 0,02755085 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 9,365E-03 0,02752865 ! oligosaccharyltransferase complex GO:0008250 8 8 0,000 9,365E-03 0,02750649 ! lipoprotein transport GO:0042953 9 8 0,000 9,365E-03 0,02748436 ! estrogen metabolic process GO:0008210 8 8 0,000 9,365E-03 0,02746226 ! nucleocytoplasmic transporter activity GO:0005487 8 8 0,000 9,365E-03 0,0274402 ! glucocorticoid metabolic process GO:0008211 8 8 0,000 9,365E-03 0,02741818 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 8 8 0,000 9,365E-03 0,02739619 ! T-helper 1 type immune response GO:0042088 8 8 0,000 9,365E-03 0,02737424 ! amyloid precursor protein catabolic process GO:0042987 10 8 0,000 9,365E-03 0,02735233 ! response to amphetamine GO:0001975 11 8 0,000 9,365E-03 0,02733044 ! mechanosensory behavior GO:0007638 8 8 0,000 9,365E-03 0,0273086 ! detection of chemical stimulus involved in sensory perception GO:0050907 8 8 0,000 9,365E-03 0,02728678 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 9,365E-03 0,02726501 ! C-X-C chemokine binding GO:0019958 8 8 0,000 9,365E-03 0,02724327 ! two-component signal transduction system (phosphorelay) GO:0000160 9 8 0,000 9,365E-03 0,02722156 ! glycerolipid catabolic process GO:0046503 17 8 0,000 9,365E-03 0,02719988 ! spinal cord dorsal/ventral patterning GO:0021513 10 8 0,000 9,365E-03 0,02717825 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 9 8 0,000 9,365E-03 0,02715664 ! inositol phosphate-mediated signaling GO:0048016 9 8 0,000 9,365E-03 0,02713507 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 9,365E-03 0,02711354 ! pigment granule organization GO:0048753 9 8 0,000 9,365E-03 0,02709203 ! GTP-dependent protein binding GO:0030742 11 8 0,000 9,365E-03 0,02707057 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 9,365E-03 0,02704913 ! regulation of interleukin-8 biosynthetic process GO:0045414 9 8 0,000 9,365E-03 0,02702773 ! regulation of pigmentation during development GO:0048070 11 8 0,000 9,365E-03 0,02700637 ! macrophage activation GO:0042116 8 8 0,000 9,365E-03 0,02698504 ! poly(A) RNA binding GO:0008143 8 8 0,000 9,365E-03 0,02696374 ! positive regulation of insulin secretion GO:0032024 10 8 0,000 9,365E-03 0,02694247 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 18 8 0,000 9,365E-03 0,02692124 ! asymmetric protein localization GO:0008105 9 8 0,000 9,365E-03 0,02690004 ! nucleotide-sugar transmembrane transporter activity GO:0005338 8 8 0,000 9,365E-03 0,02687888 ! neurotrophin binding GO:0043121 10 8 0,000 9,365E-03 0,02685775 ! nucleoside transmembrane transporter activity GO:0005337 9 8 0,000 9,365E-03 0,02683665 ! positive regulation of multicellular organismal metabolic process GO:0044253 9 8 0,000 9,365E-03 0,02681558 ! phagocytosis, engulfment GO:0006911 10 8 0,000 9,365E-03 0,02679455 ! UDP-glucosyltransferase activity GO:0035251 8 8 0,000 9,365E-03 0,02677355 ! neurotransmitter biosynthetic process GO:0042136 9 8 0,000 9,365E-03 0,02675259 ! UV protection GO:0009650 9 8 0,000 9,365E-03 0,02673165 ! peptidyl-proline dioxygenase activity GO:0031543 8 8 0,000 9,365E-03 0,02671075 ! eukaryotic translation initiation factor 4F complex GO:0016281 10 8 0,000 9,365E-03 0,02668989 ! glutathione peroxidase activity GO:0004602 17 8 0,000 9,365E-03 0,02666905 ! acyl-CoA thioesterase activity GO:0016291 10 8 0,000 9,365E-03 0,02664825 ! ATP-binding cassette (ABC) transporter complex GO:0043190 8 8 0,000 9,365E-03 0,02662748 ! ferric iron binding GO:0008199 9 8 0,000 9,365E-03 0,02660674 ! response to UV-B GO:0010224 10 8 0,000 9,365E-03 0,02658603 ! intermediate filament organization GO:0045109 8 8 0,000 9,365E-03 0,02656536 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 9,365E-03 0,02654472 ! cellular extravasation GO:0045123 9 8 0,000 9,365E-03 0,02652411 ! skeletal muscle contraction GO:0003009 8 8 0,000 9,365E-03 0,02650353 ! positive regulation of cytokine production during immune response GO:0002720 8 8 0,000 9,365E-03 0,02648299 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 9,365E-03 0,02646247 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 9,365E-03 0,02644199 ! positive regulation of systemic arterial blood pressure GO:0003084 10 8 0,000 9,365E-03 0,02642154 ! negative regulation of systemic arterial blood pressure GO:0003085 9 8 0,000 9,365E-03 0,02640112 ! respiratory chain complex IV assembly GO:0008535 8 8 0,000 9,365E-03 0,02638074 ! erythrocyte development GO:0048821 9 8 0,000 9,365E-03 0,02636038 ! regulation of interleukin-10 production GO:0032653 8 8 0,000 9,365E-03 0,02634006 ! ribosome assembly GO:0042255 8 8 0,000 9,365E-03 0,02631976 ! gamma-tubulin binding GO:0043015 8 8 0,000 9,365E-03 0,0262995 ! NADPH oxidase complex GO:0043020 8 8 0,000 9,365E-03 0,02627927 ! mRNA cleavage GO:0006379 9 8 0,000 9,365E-03 0,02625907 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 9 8 0,000 9,365E-03 0,02623891 ! opioid receptor activity GO:0004985 8 8 0,000 9,365E-03 0,02621877 ! zymogen activation GO:0031638 9 8 0,000 9,365E-03 0,02619866 ! coenzyme A metabolic process GO:0015936 8 8 0,000 9,365E-03 0,02617859 ! cellular metabolic compound salvage GO:0043094 11 8 0,000 9,365E-03 0,02615854 ! costamere GO:0043034 8 8 0,000 9,365E-03 0,02613853 ! inositol trisphosphate kinase activity GO:0051766 9 8 0,000 9,365E-03 0,02611854 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 9,365E-03 0,02609859 ! sarcomere organization GO:0045214 9 8 0,000 9,365E-03 0,02607867 ! wide pore channel activity GO:0022829 9 8 0,000 9,365E-03 0,02605878 ! ligand-regulated transcription factor activity GO:0003706 10 8 0,000 9,365E-03 0,02603891 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 9,365E-03 0,02601908 ! hormone catabolic process GO:0042447 9 8 0,000 9,365E-03 0,02599928 ! mRNA 3'-UTR binding GO:0003730 9 8 0,000 9,365E-03 0,02597951 ! cGMP biosynthetic process GO:0006182 9 8 0,000 9,365E-03 0,02595977 ! lysozyme activity GO:0003796 10 8 0,000 9,365E-03 0,02594006 ! death receptor binding GO:0005123 8 8 0,000 9,365E-03 0,02592038 ! protein modification by small protein removal GO:0070646 9 8 0,000 9,365E-03 0,02590072 ! adult feeding behavior GO:0008343 9 8 0,000 9,365E-03 0,0258811 ! microtubule basal body GO:0005932 8 8 0,000 9,365E-03 0,02586151 ! pyrimidine nucleotide catabolic process GO:0006244 8 8 0,000 9,365E-03 0,02584195 ! interleukin-1 receptor binding GO:0005149 9 8 0,000 9,365E-03 0,02582241 ! calcium-release channel activity GO:0015278 8 8 0,000 9,365E-03 0,02580291 ! positive regulation of smooth muscle contraction GO:0045987 9 8 0,000 9,365E-03 0,02578344 ! behavioral response to nicotine GO:0035095 9 8 0,000 9,365E-03 0,02576399 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 9,365E-03 0,02574458 ! adenosine deaminase activity GO:0004000 8 8 0,000 9,365E-03 0,02572519 ! NAD biosynthetic process GO:0009435 9 8 0,000 9,365E-03 0,02570584 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 9 0,000 0,01052958 0,02888113 ! positive regulation of glycogen biosynthetic process GO:0045725 9 9 0,000 0,01052958 0,02885943 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 0,01052958 0,02883776 ! sodium:hydrogen antiporter activity GO:0015385 9 9 0,000 0,01052958 0,02881613 GO:0005451|monovalent cation:hydrogen antiporter activity, ! cGMP metabolic process GO:0046068 10 9 0,000 0,01052958 0,02879453 ! myotube differentiation GO:0014902 9 9 0,000 0,01052958 0,02877296 ! folic acid and derivative biosynthetic process GO:0009396 9 9 0,000 0,01052958 0,02875142 ! N-glycan processing GO:0006491 10 9 0,000 0,01052958 0,02872992 ! regulation of epidermal growth factor receptor activity GO:0007176 11 9 0,000 0,01052958 0,02870845 ! actin-myosin filament sliding GO:0033275 11 9 0,000 0,01052958 0,02868701 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! axon part GO:0033267 12 9 0,000 0,01052958 0,0286656 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 10 9 0,000 0,01052958 0,02864422 ! RNA methylation GO:0001510 9 9 0,000 0,01052958 0,02862288 ! prostaglandin biosynthetic process GO:0001516 9 9 0,000 0,01052958 0,02860156 GO:0046457|prostanoid biosynthetic process, ! negative regulation of gene-specific transcription GO:0032582 10 9 0,000 0,01052958 0,02858028 ! artery development GO:0060840 9 9 0,000 0,01052958 0,02855903 GO:0048844|artery morphogenesis, ! axonemal dynein complex GO:0005858 9 9 0,000 0,01052958 0,02853782 ! regulation of postsynaptic membrane potential GO:0060078 11 9 0,000 0,01052958 0,02851663 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 9 9 0,000 0,01052958 0,02849548 ! auditory receptor cell differentiation GO:0042491 10 9 0,000 0,01052958 0,02847435 ! positive regulation of heart contraction GO:0045823 11 9 0,000 0,01052958 0,02845326 ! lipopolysaccharide binding GO:0001530 9 9 0,000 0,01052958 0,0284322 ! regulated secretory pathway GO:0045055 10 9 0,000 0,01052958 0,02841117 ! estrogen receptor binding GO:0030331 9 9 0,000 0,01052958 0,02839017 ! inner mitochondrial membrane organization GO:0007007 10 9 0,000 0,01052958 0,0283692 ! telomere maintenance via telomerase GO:0007004 20 9 0,000 0,01052958 0,02834827 GO:0006278|RNA-dependent DNA replication, ! L-phenylalanine metabolic process GO:0006558 9 9 0,000 0,01052958 0,02832736 GO:0006559|L-phenylalanine catabolic process, ! indolalkylamine metabolic process GO:0006586 9 9 0,000 0,01052958 0,02830649 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! urea metabolic process GO:0019627 19 9 0,000 0,01052958 0,02828564 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! smooth endoplasmic reticulum GO:0005790 11 9 0,000 0,01052958 0,02826483 ! autophagic vacuole GO:0005776 11 9 0,000 0,01052958 0,02824404 ! Rac GTPase binding GO:0048365 10 9 0,000 0,01052958 0,02822329 ! response to dietary excess GO:0002021 9 9 0,000 0,01052958 0,02820257 ! regulation of sodium ion transport GO:0002028 10 9 0,000 0,01052958 0,02818188 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 0,01052958 0,02816122 ! lens development in camera-type eye GO:0002088 9 9 0,000 0,01052958 0,02814059 ! male sex determination GO:0030238 9 9 0,000 0,01052958 0,02811999 ! positive regulation of vasodilation GO:0045909 19 9 0,000 0,01052958 0,02809942 ! positive regulation of muscle contraction GO:0045933 11 9 0,000 0,01052958 0,02807888 ! regulation of smoothened signaling pathway GO:0008589 11 9 0,000 0,01052958 0,02805836 ! male germ cell nucleus GO:0001673 11 9 0,000 0,01052958 0,02803788 ! negative regulation of foam cell differentiation GO:0010745 12 9 0,000 0,01052958 0,02801743 ! copper ion homeostasis GO:0055070 9 9 0,000 0,01052958 0,02799701 ! protein heterooligomerization GO:0051291 10 9 0,000 0,01052958 0,02797662 ! spectrin GO:0008091 9 9 0,000 0,01052958 0,02795626 ! cardiac muscle cell differentiation GO:0055007 12 9 0,000 0,01052958 0,02793593 ! purine nucleoside triphosphate catabolic process GO:0009146 9 9 0,000 0,01052958 0,02791563 ! synaptic vesicle exocytosis GO:0016079 10 9 0,000 0,01052958 0,02789535 ! regulation of B cell differentiation GO:0045577 10 9 0,000 0,01052958 0,02787511 ! cell differentiation in hindbrain GO:0021533 10 9 0,000 0,01052958 0,0278549 ! neural tube patterning GO:0021532 10 9 0,000 0,01052958 0,02783471 ! fucose catabolic process GO:0019317 10 9 0,000 0,01052958 0,02781456 GO:0042355|L-fucose catabolic process, ! retinal ganglion cell axon guidance GO:0031290 10 9 0,000 0,01052958 0,02779443 ! regulation of hormone metabolic process GO:0032350 12 9 0,000 0,01052958 0,02777433 ! sterol catabolic process GO:0016127 10 9 0,000 0,01052958 0,02775426 GO:0006707|cholesterol catabolic process, ! oligosaccharyl transferase activity GO:0004576 9 9 0,000 0,01052958 0,02773422 ! clathrin coat of coated pit GO:0030132 11 9 0,000 0,01052958 0,02771421 ! SNARE complex GO:0031201 11 9 0,000 0,01052958 0,02769423 ! negative regulation of osteoclast differentiation GO:0045671 10 9 0,000 0,01052958 0,02767428 ! negative regulation of glucose transport GO:0010829 10 9 0,000 0,01052958 0,02765436 ! methionine biosynthetic process GO:0009086 11 9 0,000 0,01052958 0,02763446 ! peptidoglycan binding GO:0042834 9 9 0,000 0,01052958 0,02761459 ! serine family amino acid biosynthetic process GO:0009070 10 9 0,000 0,01052958 0,02759476 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 0,01052958 0,02757495 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! nicotinamide nucleotide biosynthetic process GO:0019359 10 9 0,000 0,01052958 0,02755517 ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 9 9 0,000 0,01052958 0,02753541 GO:0003756|protein disulfide isomerase activity, ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 0,01052958 0,02751569 ! beta-1,3-galactosyltransferase activity GO:0048531 10 9 0,000 0,01052958 0,02749599 ! detection of bacterium GO:0016045 10 9 0,000 0,01052958 0,02747632 ! lymphocyte activation during immune response GO:0002285 9 9 0,000 0,01052958 0,02745668 ! embryonic gut development GO:0048566 10 9 0,000 0,01052958 0,02743707 ! hydrolase activity, acting on ether bonds GO:0016801 10 9 0,000 0,01052958 0,02741749 ! desmosome GO:0030057 10 9 0,000 0,01052958 0,02739793 ! long-chain-fatty-acid-CoA ligase activity GO:0004467 9 9 0,000 0,01052958 0,0273784 ! T cell receptor signaling pathway GO:0050852 14 9 0,000 0,01052958 0,0273589 ! positive regulation of calcium-mediated signaling GO:0050850 11 9 0,000 0,01052958 0,02733943 ! actin filament polymerization GO:0030041 10 9 0,000 0,01052958 0,02731999 ! negative regulation of B cell activation GO:0050869 10 9 0,000 0,01052958 0,02730057 ! establishment of cell polarity GO:0030010 10 9 0,000 0,01052958 0,02728118 ! regulation of synapse organization GO:0050807 10 9 0,000 0,01052958 0,02726182 ! septin complex GO:0031105 10 9 0,000 0,01052958 0,02724248 GO:0032156|septin cytoskeleton, ! cholesterol transporter activity GO:0017127 9 9 0,000 0,01052958 0,02722318 ! anchoring collagen GO:0030934 9 9 0,000 0,01052958 0,0272039 ! defense response to Gram-negative bacterium GO:0050829 10 9 0,000 0,01052958 0,02718464 ! regulation of developmental growth GO:0048638 11 9 0,000 0,01052958 0,02716542 ! negative regulation of smooth muscle cell proliferation GO:0048662 10 9 0,000 0,01052958 0,02714622 ! GMP binding GO:0019002 11 9 0,000 0,01052958 0,02712705 GO:0030553|cGMP binding, ! photoreceptor activity GO:0009881 10 9 0,000 0,01052958 0,0271079 ! virus-host interaction GO:0019048 13 9 0,000 0,01052958 0,02708879 ! pentose-phosphate shunt GO:0006098 11 9 0,000 0,01052958 0,0270697 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 0,01052958 0,02705063 ! negative regulation of lipid catabolic process GO:0050995 11 9 0,000 0,01052958 0,0270316 ! non-recombinational repair GO:0000726 10 9 0,000 0,01052958 0,02701259 GO:0006303|double-strand break repair via nonhomologous end joining, ! cell volume homeostasis GO:0006884 10 9 0,000 0,01052958 0,02699361 ! nuclear telomere cap complex GO:0000783 10 9 0,000 0,01052958 0,02697465 GO:0000782|telomere cap complex, ! activin binding GO:0048185 10 9 0,000 0,01052958 0,02695572 ! social behavior GO:0035176 10 9 0,000 0,01052958 0,02693682 ! regulation of positive chemotaxis GO:0050926 11 9 0,000 0,01052958 0,02691794 GO:0050927|positive regulation of positive chemotaxis, ! perikaryon GO:0043204 11 9 0,000 0,01052958 0,02689909 ! nitric oxide biosynthetic process GO:0006809 10 9 0,000 0,01052958 0,02688027 ! mating GO:0007618 11 9 0,000 0,01052958 0,02686147 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 9 0,000 0,01052958 0,0268427 ! rhythmic behavior GO:0007622 11 9 0,000 0,01052958 0,02682395 ! phospholipid efflux GO:0033700 10 9 0,000 0,01052958 0,02680523 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 0,01052958 0,02678654 ! poly-purine tract binding GO:0070717 9 9 0,000 0,01052958 0,02676788 ! T cell proliferation GO:0042098 10 9 0,000 0,01052958 0,02674923 ! retinol dehydrogenase activity GO:0004745 9 9 0,000 0,01052958 0,02673062 ! negative regulation of cell-matrix adhesion GO:0001953 10 9 0,000 0,01052958 0,02671203 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 9 9 0,000 0,01052958 0,02669347 ! interleukin-1 binding GO:0019966 10 9 0,000 0,01052958 0,02667493 ! glucosyltransferase activity GO:0046527 9 9 0,000 0,01052958 0,02665642 ! platelet-derived growth factor receptor signaling pathway GO:0048008 14 9 0,000 0,01052958 0,02663793 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 11 9 0,000 0,01052958 0,02661947 ! ovulation GO:0030728 9 9 0,000 0,01052958 0,02660104 ! acid phosphatase activity GO:0003993 18 9 0,000 0,01052958 0,02658263 ! embryonic cranial skeleton morphogenesis GO:0048701 10 9 0,000 0,01052958 0,02656425 ! ER overload response GO:0006983 11 9 0,000 0,01052958 0,02654589 ! B cell proliferation GO:0042100 10 9 0,000 0,01052958 0,02652756 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 11 9 0,000 0,01052958 0,02650925 ! calcium-transporting ATPase activity GO:0005388 11 9 0,000 0,01052958 0,02649097 ! mannose metabolic process GO:0006013 13 9 0,000 0,01052958 0,02647271 ! lipid digestion GO:0044241 11 9 0,000 0,01052958 0,02645448 ! tumor necrosis factor binding GO:0043120 9 9 0,000 0,01052958 0,02643627 ! tRNA methyltransferase activity GO:0008175 9 9 0,000 0,01052958 0,02641809 ! regulation of bone resorption GO:0045124 10 9 0,000 0,01052958 0,02639993 ! brain morphogenesis GO:0048854 9 9 0,000 0,01052958 0,0263818 ! positive regulation of alpha-beta T cell differentiation GO:0046638 10 9 0,000 0,01052958 0,02636369 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 10 9 0,000 0,01052958 0,02634561 ! synaptic vesicle membrane GO:0030672 9 9 0,000 0,01052958 0,02632755 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 9 0,000 0,01052958 0,02630952 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9 9 0,000 0,01052958 0,02629151 ! kinesin binding GO:0019894 9 9 0,000 0,01052958 0,02627353 ! multicellular organismal aging GO:0010259 18 9 0,000 0,01052958 0,02625557 ! Ran GTPase binding GO:0008536 11 9 0,000 0,01052958 0,02623764 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 0,01052958 0,02621973 ! protein import into peroxisome matrix GO:0016558 9 9 0,000 0,01052958 0,02620184 ! mRNA polyadenylation GO:0006378 10 9 0,000 0,01052958 0,02618398 ! neuropeptide Y receptor activity GO:0004983 10 9 0,000 0,01052958 0,02616615 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 14 9 0,000 0,01052958 0,02614833 ! prostaglandin receptor activity GO:0004955 11 9 0,000 0,01052958 0,02613054 ! adrenoceptor activity GO:0004935 12 9 0,000 0,01052958 0,02611278 ! regulation of isotype switching GO:0045191 9 9 0,000 0,01052958 0,02609504 ! positive regulation of leukocyte migration GO:0002687 10 9 0,000 0,01052958 0,02607733 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 10 9 0,000 0,01052958 0,02605963 ! positive regulation of ATPase activity GO:0032781 11 9 0,000 0,01052958 0,02604197 ! nonprotein amino acid metabolic process GO:0019794 19 9 0,000 0,01052958 0,02602432 ! ionotropic glutamate receptor complex GO:0008328 14 9 0,000 0,01052958 0,0260067 ! Notch binding GO:0005112 10 9 0,000 0,01052958 0,02598911 ! ATPase regulator activity GO:0060590 10 9 0,000 0,01052958 0,02597154 ! pyrimidine base metabolic process GO:0006206 10 9 0,000 0,01052958 0,02595399 ! establishment or maintenance of apical/basal cell polarity GO:0035088 10 9 0,000 0,01052958 0,02593646 ! tubulin-tyrosine ligase activity GO:0004835 10 9 0,000 0,01052958 0,02591896 ! alcohol dehydrogenase (NAD) activity GO:0004022 10 9 0,000 0,01052958 0,02590148 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 12 10 0,000 0,01169298 0,02874392 ! oligosaccharide biosynthetic process GO:0009312 10 10 0,000 0,01169298 0,02872456 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 10 0,000 0,01169298 0,02870523 ! sleep GO:0030431 11 10 0,000 0,01169298 0,02868593 ! positive regulation of lipid biosynthetic process GO:0046889 10 10 0,000 0,01169298 0,02866665 ! lipid particle GO:0005811 10 10 0,000 0,01169298 0,0286474 ! filopodium assembly GO:0046847 14 10 0,000 0,01169298 0,02862817 ! UTP metabolic process GO:0046051 12 10 0,000 0,01169298 0,02860897 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 13 10 0,000 0,01169298 0,0285898 ! guanylate kinase activity GO:0004385 14 10 0,000 0,01169298 0,02857065 ! integral to mitochondrial membrane GO:0032592 10 10 0,000 0,01169298 0,02855153 ! COPI coating of Golgi vesicle GO:0048205 11 10 0,000 0,01169298 0,02853243 GO:0048200|Golgi transport vesicle coating, ! platelet alpha granule membrane GO:0031092 11 10 0,000 0,01169298 0,02851335 ! macromolecule transmembrane transporter activity GO:0022884 11 10 0,000 0,01169298 0,02849431 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 10 0,000 0,01169298 0,02847529 ! thyroid hormone receptor coactivator activity GO:0030375 11 10 0,000 0,01169298 0,02845629 GO:0010861|thyroid hormone receptor activator activity, ! regulation of receptor activity GO:0010469 12 10 0,000 0,01169298 0,02843732 ! lung alveolus development GO:0048286 11 10 0,000 0,01169298 0,02841837 ! regulation of chemokine biosynthetic process GO:0045073 11 10 0,000 0,01169298 0,02839945 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01169298 0,02838056 ! negative regulation of striated muscle development GO:0045843 11 10 0,000 0,01169298 0,02836169 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 0,01169298 0,02834284 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 11 10 0,000 0,01169298 0,02832402 ! regulation of mRNA processing GO:0050684 12 10 0,000 0,01169298 0,02830523 ! positive regulation of survival gene product expression GO:0045885 12 10 0,000 0,01169298 0,02828646 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 11 10 0,000 0,01169298 0,02826771 ! transforming growth factor beta binding GO:0050431 11 10 0,000 0,01169298 0,02824899 ! histidine metabolic process GO:0006547 10 10 0,000 0,01169298 0,0282303 GO:0009075|histidine family amino acid metabolic process, ! glucan biosynthetic process GO:0009250 10 10 0,000 0,01169298 0,02821163 GO:0005978|glycogen biosynthetic process, ! endosome organization GO:0007032 13 10 0,000 0,01169298 0,02819298 ! death receptor activity GO:0005035 11 10 0,000 0,01169298 0,02817436 ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 0,01169298 0,02815576 ! entry into host cell GO:0030260 11 10 0,000 0,01169298 0,02813719 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 10 10 0,000 0,01169298 0,02811864 ! filamentous actin GO:0031941 11 10 0,000 0,01169298 0,02810012 ! behavioral fear response GO:0001662 12 10 0,000 0,01169298 0,02808162 GO:0002209|behavioral defense response, ! bone mineralization GO:0030282 12 10 0,000 0,01169298 0,02806314 ! negative regulation of ossification GO:0030279 12 10 0,000 0,01169298 0,02804469 ! phosphatidylcholine biosynthetic process GO:0006656 11 10 0,000 0,01169298 0,02802627 ! macrophage differentiation GO:0030225 11 10 0,000 0,01169298 0,02800787 ! positive regulation of phagocytosis GO:0050766 11 10 0,000 0,01169298 0,02798949 ! recycling endosome membrane GO:0055038 11 10 0,000 0,01169298 0,02797113 ! regulation of fat cell differentiation GO:0045598 11 10 0,000 0,01169298 0,0279528 ! snRNA metabolic process GO:0016073 10 10 0,000 0,01169298 0,0279345 GO:0016180|snRNA processing, ! glycosphingolipid biosynthetic process GO:0006688 11 10 0,000 0,01169298 0,02791622 ! regulation of mitochondrial membrane potential GO:0051881 11 10 0,000 0,01169298 0,02789796 ! purine ribonucleotide catabolic process GO:0009154 10 10 0,000 0,01169298 0,02787972 ! immunoglobulin production during immune response GO:0002381 10 10 0,000 0,01169298 0,02786151 ! nitric oxide metabolic process GO:0046209 20 10 0,000 0,01169298 0,02784333 ! induction of an organ GO:0001759 12 10 0,000 0,01169298 0,02782517 ! response to estradiol stimulus GO:0032355 11 10 0,000 0,01169298 0,02780703 ! synaptic vesicle endocytosis GO:0048488 12 10 0,000 0,01169298 0,02778891 ! negative regulation of MAPKKK cascade GO:0043409 12 10 0,000 0,01169298 0,02777082 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 10 0,000 0,01169298 0,02775275 ! MHC class II receptor activity GO:0032395 14 10 0,000 0,01169298 0,02773471 ! peptidyl-lysine modification GO:0018205 11 10 0,000 0,01169298 0,02771669 ! ribonuclease P activity GO:0004526 10 10 0,000 0,01169298 0,02769869 ! COPI vesicle coat GO:0030126 12 10 0,000 0,01169298 0,02768071 GO:0030663|COPI coated vesicle membrane, ! telomere maintenance via telomere lengthening GO:0010833 21 10 0,000 0,01169298 0,02766276 ! vitamin transporter activity GO:0051183 12 10 0,000 0,01169298 0,02764483 ! snRNA binding GO:0017069 11 10 0,000 0,01169298 0,02762693 ! negative regulation of osteoblast differentiation GO:0045668 12 10 0,000 0,01169298 0,02760905 ! heparan sulfate sulfotransferase activity GO:0034483 10 10 0,000 0,01169298 0,02759119 ! fatty-acid ligase activity GO:0015645 10 10 0,000 0,01169298 0,02757335 ! intramolecular transferase activity, phosphotransferases GO:0016868 11 10 0,000 0,01169298 0,02755554 ! quaternary ammonium group transport GO:0015697 10 10 0,000 0,01169298 0,02753775 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 10 10 0,000 0,01169298 0,02751999 ! metalloenzyme inhibitor activity GO:0048551 11 10 0,000 0,01169298 0,02750224 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! anterior/posterior axis specification GO:0009948 14 10 0,000 0,01169298 0,02748452 ! regulation of RNA splicing GO:0043484 13 10 0,000 0,01169298 0,02746682 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 10 10 0,000 0,01169298 0,02744915 ! trophectodermal cell differentiation GO:0001829 11 10 0,000 0,01169298 0,0274315 ! positive regulation of neuron apoptosis GO:0043525 11 10 0,000 0,01169298 0,02741387 ! extracellular matrix binding GO:0050840 11 10 0,000 0,01169298 0,02739626 ! regulation of synapse structure and activity GO:0050803 11 10 0,000 0,01169298 0,02737868 ! autophagic vacuole formation GO:0000045 11 10 0,000 0,01169298 0,02736112 ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 0,01169298 0,02734358 ! negative regulation of cell projection organization GO:0031345 14 10 0,000 0,01169298 0,02732606 ! rough endoplasmic reticulum membrane GO:0030867 10 10 0,000 0,01169298 0,02730857 ! thyroid gland development GO:0030878 12 10 0,000 0,01169298 0,02729109 ! DNA bending activity GO:0008301 11 10 0,000 0,01169298 0,02727364 ! neutral lipid biosynthetic process GO:0046460 10 10 0,000 0,01169298 0,02725622 GO:0046463|acylglycerol biosynthetic process, ! embryonic hindlimb morphogenesis GO:0035116 11 10 0,000 0,01169298 0,02723881 ! embryonic forelimb morphogenesis GO:0035115 12 10 0,000 0,01169298 0,02722143 ! regulation of glucan biosynthetic process GO:0010962 10 10 0,000 0,01169298 0,02720407 GO:0005979|regulation of glycogen biosynthetic process, GO:0032885|regulation of polysaccharide biosynthetic process, ! secondary active sulfate transmembrane transporter activity GO:0008271 11 10 0,000 0,01169298 0,02718673 ! regulation of glycolysis GO:0006110 11 10 0,000 0,01169298 0,02716941 ! nucleotidase activity GO:0008252 10 10 0,000 0,01169298 0,02715212 ! phosphatidylinositol phosphate kinase activity GO:0016307 11 10 0,000 0,01169298 0,02713485 ! dipeptidyl-peptidase activity GO:0008239 12 10 0,000 0,01169298 0,0271176 ! androgen metabolic process GO:0008209 11 10 0,000 0,01169298 0,02710037 ! lateral plasma membrane GO:0016328 13 10 0,000 0,01169298 0,02708316 ! MAP kinase kinase activity GO:0004708 12 10 0,000 0,01169298 0,02706598 ! cation:amino acid symporter activity GO:0005416 12 10 0,000 0,01169298 0,02704881 ! startle response GO:0001964 13 10 0,000 0,01169298 0,02703167 ! amyloid precursor protein metabolic process GO:0042982 12 10 0,000 0,01169298 0,02701455 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 12 10 0,000 0,01169298 0,02699745 ! positive regulation of endothelial cell proliferation GO:0001938 13 10 0,000 0,01169298 0,02698038 ! 3'-5'-exoribonuclease activity GO:0000175 10 10 0,000 0,01169298 0,02696332 ! spinal cord patterning GO:0021511 12 10 0,000 0,01169298 0,02694629 ! peptide or protein amino-terminal blocking GO:0018409 11 10 0,000 0,01169298 0,02692928 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 10 10 0,000 0,01169298 0,02691229 GO:0033549|MAP kinase phosphatase activity, ! response to X-ray GO:0010165 11 10 0,000 0,01169298 0,02689532 ! embryonic eye morphogenesis GO:0048048 14 10 0,000 0,01169298 0,02687837 ! sodium:potassium-exchanging ATPase activity GO:0005391 12 10 0,000 0,01169298 0,02686145 ! zinc ion transmembrane transporter activity GO:0005385 13 10 0,000 0,01169298 0,02684454 ! positive regulation of glycogen metabolic process GO:0070875 11 10 0,000 0,01169298 0,02682766 ! glucose transmembrane transporter activity GO:0005355 10 10 0,000 0,01169298 0,0268108 ! regulation of intracellular pH GO:0051453 10 10 0,000 0,01169298 0,02679396 ! retrograde transport, endosome to Golgi GO:0042147 12 10 0,000 0,01169298 0,02677714 ! regulation of multicellular organismal metabolic process GO:0044246 11 10 0,000 0,01169298 0,02676034 ! adult heart development GO:0007512 14 10 0,000 0,01169298 0,02674356 ! neuromuscular junction development GO:0007528 12 10 0,000 0,01169298 0,0267268 ! carbohydrate phosphatase activity GO:0019203 11 10 0,000 0,01169298 0,02671007 ! O-methyltransferase activity GO:0008171 10 10 0,000 0,01169298 0,02669335 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 10 10 0,000 0,01169298 0,02667666 ! signalosome GO:0008180 10 10 0,000 0,01169298 0,02665999 ! lysophospholipase activity GO:0004622 19 10 0,000 0,01169298 0,02664333 ! prefoldin complex GO:0016272 10 10 0,000 0,01169298 0,0266267 ! alpha-beta T cell differentiation GO:0046632 12 10 0,000 0,01169298 0,02661009 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 10 0,000 0,01169298 0,0265935 ! positive regulation of T cell mediated immunity GO:0002711 10 10 0,000 0,01169298 0,02657693 ! nucleoside bisphosphate metabolic process GO:0033865 10 10 0,000 0,01169298 0,02656039 ! endocytic vesicle membrane GO:0030666 10 10 0,000 0,01169298 0,02654386 ! gland morphogenesis GO:0022612 11 10 0,000 0,01169298 0,02652735 ! icosanoid receptor activity GO:0004953 13 10 0,000 0,01169298 0,02651086 GO:0004954|prostanoid receptor activity, ! regulation of macrophage activation GO:0043030 11 10 0,000 0,01169298 0,0264944 ! peptide transporter activity GO:0015197 10 10 0,000 0,01169298 0,02647795 ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 10 10 0,000 0,01169298 0,02646153 ! regulation of leukocyte migration GO:0002685 11 10 0,000 0,01169298 0,02644512 ! muscle maintenance GO:0046716 10 10 0,000 0,01169298 0,02642874 ! acid secretion GO:0046717 12 10 0,000 0,01169298 0,02641237 ! retinoid-X receptor activity GO:0004886 11 10 0,000 0,01169298 0,02639603 ! catecholamine biosynthetic process GO:0042423 11 10 0,000 0,01169298 0,0263797 ! thyroid hormone metabolic process GO:0042403 11 10 0,000 0,01169298 0,0263634 ! GTPase inhibitor activity GO:0005095 21 10 0,000 0,01169298 0,02634711 ! somatic recombination of immunoglobulin gene segments GO:0016447 10 10 0,000 0,01169298 0,02633085 ! pattern recognition receptor activity GO:0008329 10 10 0,000 0,01169298 0,02631461 ! quinone cofactor metabolic process GO:0042375 11 10 0,000 0,01169298 0,02629838 ! regulation of organic acid transport GO:0032890 12 10 0,000 0,01169298 0,02628218 ! platelet-derived growth factor receptor binding GO:0005161 14 10 0,000 0,01169298 0,026266 ! C-acyltransferase activity GO:0016408 12 10 0,000 0,01169298 0,02624983 ! cAMP-dependent protein kinase complex GO:0005952 12 10 0,000 0,01169298 0,02623369 ! water channel activity GO:0015250 15 10 0,000 0,01169298 0,02621757 ! phospholipase inhibitor activity GO:0004859 10 10 0,000 0,01169298 0,02620146 ! regulation of embryonic development GO:0045995 12 10 0,000 0,01169298 0,02618538 ! acrosome reaction GO:0007340 12 10 0,000 0,01169298 0,02616931 ! mitochondrion localization GO:0051646 10 10 0,000 0,01169298 0,02615327 ! cilium part GO:0044441 10 10 0,000 0,01169298 0,02613724 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 12 11 0,000 0,01285507 0,02871726 ! 'de novo' posttranslational protein folding GO:0051084 11 11 0,000 0,01285507 0,02869969 ! negative regulation of blood pressure GO:0045776 13 11 0,000 0,01285507 0,02868214 ! cadmium ion binding GO:0046870 15 11 0,000 0,01285507 0,0286646 ! hemoglobin complex GO:0005833 13 11 0,000 0,01285507 0,02864709 ! CTP metabolic process GO:0046036 13 11 0,000 0,01285507 0,0286296 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0009148|pyrimidine nucleoside triphosphate biosynthetic process, ! regulation of neurotransmitter secretion GO:0046928 12 11 0,000 0,01285507 0,02861214 ! response to pain GO:0048265 12 11 0,000 0,01285507 0,02859469 ! regulation of viral genome replication GO:0045069 13 11 0,000 0,01285507 0,02857727 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 11 11 0,000 0,01285507 0,02855986 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 12 11 0,000 0,01285507 0,02854248 ! nucleotide-sugar metabolic process GO:0009225 13 11 0,000 0,01285507 0,02852512 ! regulation of catecholamine secretion GO:0050433 12 11 0,000 0,01285507 0,02850778 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 0,01285507 0,02849046 ! peptide antigen binding GO:0042605 14 11 0,000 0,01285507 0,02847316 ! polyamine metabolic process GO:0006595 11 11 0,000 0,01285507 0,02845588 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 13 11 0,000 0,01285507 0,02843863 GO:0045125|bioactive lipid receptor activity, ! nucleobase biosynthetic process GO:0046112 13 11 0,000 0,01285507 0,02842139 ! regulation of calcium ion transport into cytosol GO:0010522 15 11 0,000 0,01285507 0,02840418 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 12 11 0,000 0,01285507 0,02838698 GO:0002717|positive regulation of natural killer cell mediated immunity, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 12 11 0,000 0,01285507 0,02836981 ! protein homotetramerization GO:0051289 13 11 0,000 0,01285507 0,02835266 ! regulation of gliogenesis GO:0014013 13 11 0,000 0,01285507 0,02833552 GO:0045685|regulation of glial cell differentiation, ! oligodendrocyte development GO:0014003 11 11 0,000 0,01285507 0,02831841 ! cytoskeletal adaptor activity GO:0008093 17 11 0,000 0,01285507 0,02830132 ! regulation of circadian rhythm GO:0042752 11 11 0,000 0,01285507 0,02828425 ! low-density lipoprotein receptor binding GO:0050750 11 11 0,000 0,01285507 0,0282672 ! response to dsRNA GO:0043331 21 11 0,000 0,01285507 0,02825018 ! response to amine stimulus GO:0014075 15 11 0,000 0,01285507 0,02823317 GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 14 11 0,000 0,01285507 0,02821618 ! sphingomyelin metabolic process GO:0006684 13 11 0,000 0,01285507 0,02819921 ! cell wall macromolecule catabolic process GO:0016998 14 11 0,000 0,01285507 0,02818227 ! spinal cord motor neuron differentiation GO:0021522 12 11 0,000 0,01285507 0,02816534 ! retinal binding GO:0016918 11 11 0,000 0,01285507 0,02814844 ! leukocyte activation during immune response GO:0002366 11 11 0,000 0,01285507 0,02813155 GO:0002263|cell activation during immune response, ! regulation of sterol transport GO:0032371 12 11 0,000 0,01285507 0,02811468 GO:0032374|regulation of cholesterol transport, ! beta-tubulin binding GO:0048487 14 11 0,000 0,01285507 0,02809784 ! autonomic nervous system development GO:0048483 12 11 0,000 0,01285507 0,02808101 ! negative regulation of lipid transport GO:0032369 12 11 0,000 0,01285507 0,02806421 ! photoreceptor outer segment GO:0001750 12 11 0,000 0,01285507 0,02804742 ! positive regulation of interleukin-1 secretion GO:0050716 12 11 0,000 0,01285507 0,02803066 ! peptidyl-threonine modification GO:0018210 15 11 0,000 0,01285507 0,02801391 ! clathrin coat of trans-Golgi network vesicle GO:0030130 15 11 0,000 0,01285507 0,02799719 ! regulation of interleukin-1 beta secretion GO:0050706 12 11 0,000 0,01285507 0,02798049 ! regulation of epidermis development GO:0045682 14 11 0,000 0,01285507 0,0279638 ! positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 11 11 0,000 0,01285507 0,02794714 ! midbrain development GO:0030901 12 11 0,000 0,01285507 0,02793049 ! musculoskeletal movement GO:0050881 12 11 0,000 0,01285507 0,02791386 GO:0050879|multicellular organismal movement, ! histone deacetylase binding GO:0042826 11 11 0,000 0,01285507 0,02789726 ! regulation of RNA stability GO:0043487 13 11 0,000 0,01285507 0,02788067 GO:0043488|regulation of mRNA stability, ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 11 11 0,000 0,01285507 0,02786411 ! cell killing GO:0001906 13 11 0,000 0,01285507 0,02784756 ! regulation of cellular carbohydrate catabolic process GO:0043471 13 11 0,000 0,01285507 0,02783103 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 12 11 0,000 0,01285507 0,02781453 ! carbon-sulfur lyase activity GO:0016846 11 11 0,000 0,01285507 0,02779804 ! cerebellar cortex morphogenesis GO:0021696 13 11 0,000 0,01285507 0,02778157 ! regulation of blood vessel endothelial cell migration GO:0043535 13 11 0,000 0,01285507 0,02776512 ! folic acid binding GO:0005542 12 11 0,000 0,01285507 0,02774869 ! mRNA 3'-end processing GO:0031124 12 11 0,000 0,01285507 0,02773228 ! regulation of calcium-mediated signaling GO:0050848 13 11 0,000 0,01285507 0,02771589 ! positive regulation of protein polymerization GO:0032273 11 11 0,000 0,01285507 0,02769952 ! microspike assembly GO:0030035 15 11 0,000 0,01285507 0,02768317 ! lamellipodium assembly GO:0030032 22 11 0,000 0,01285507 0,02766684 ! fibrillar collagen GO:0005583 12 11 0,000 0,01285507 0,02765053 ! inner ear receptor cell differentiation GO:0060113 12 11 0,000 0,01285507 0,02763423 ! cytoplasmic sequestering of protein GO:0051220 12 11 0,000 0,01285507 0,02761796 ! negative regulation of muscle development GO:0048635 13 11 0,000 0,01285507 0,0276017 ! very-long-chain fatty acid metabolic process GO:0000038 12 11 0,000 0,01285507 0,02758547 ! synaptonemal complex GO:0000795 11 11 0,000 0,01285507 0,02756925 ! reproductive cellular process GO:0048610 13 11 0,000 0,01285507 0,02755305 ! cortical actin cytoskeleton organization GO:0030866 12 11 0,000 0,01285507 0,02753687 ! Golgi vesicle budding GO:0048194 12 11 0,000 0,01285507 0,02752071 ! response to cAMP GO:0051591 11 11 0,000 0,01285507 0,02750457 ! detection of mechanical stimulus GO:0050982 13 11 0,000 0,01285507 0,02748845 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 13 11 0,000 0,01285507 0,02747235 ! regulation of cell projection assembly GO:0060491 11 11 0,000 0,01285507 0,02745626 ! negative regulation of transcription factor import into nucleus GO:0042992 11 11 0,000 0,01285507 0,02744019 ! positive regulation of transcription factor import into nucleus GO:0042993 13 11 0,000 0,01285507 0,02742415 ! macromolecular complex remodeling GO:0034367 11 11 0,000 0,01285507 0,02740812 GO:0034368|protein-lipid complex remodeling, GO:0034369|plasma lipoprotein particle remodeling, ! protein serine/threonine/tyrosine kinase activity GO:0004712 13 11 0,000 0,01285507 0,02739211 ! glycerol ether biosynthetic process GO:0046504 11 11 0,000 0,01285507 0,02737612 ! drug transport GO:0015893 12 11 0,000 0,01285507 0,02736015 ! FMN binding GO:0010181 12 11 0,000 0,01285507 0,02734419 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 11 0,000 0,01285507 0,02732826 ! water transporter activity GO:0005372 17 11 0,000 0,01285507 0,02731234 ! regulation of glycogen metabolic process GO:0070873 12 11 0,000 0,01285507 0,02729645 GO:0032881|regulation of polysaccharide metabolic process, ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01285507 0,02728057 ! multicellular organism growth GO:0035264 12 11 0,000 0,01285507 0,02726471 ! integrator complex GO:0032039 11 11 0,000 0,01285507 0,02724886 ! L-glutamate transmembrane transporter activity GO:0005313 13 11 0,000 0,01285507 0,02723304 GO:0015172|acidic amino acid transmembrane transporter activity, ! DNA integration GO:0015074 11 11 0,000 0,01285507 0,02721723 ! brush border membrane GO:0031526 12 11 0,000 0,01285507 0,02720145 ! actin cytoskeleton reorganization GO:0031532 14 11 0,000 0,01285507 0,02718568 ! macroautophagy GO:0016236 12 11 0,000 0,01285507 0,02716993 ! protein disulfide oxidoreductase activity GO:0015035 11 11 0,000 0,01285507 0,02715419 ! neuromuscular junction GO:0031594 12 11 0,000 0,01285507 0,02713848 ! positive regulation of peptide secretion GO:0002793 13 11 0,000 0,01285507 0,02712278 ! positive regulation of alpha-beta T cell activation GO:0046635 12 11 0,000 0,01285507 0,02710711 ! organic anion transmembrane transporter activity GO:0008514 11 11 0,000 0,01285507 0,02709145 ! response to antibiotic GO:0046677 13 11 0,000 0,01285507 0,0270758 ! protein-hormone receptor activity GO:0016500 12 11 0,000 0,01285507 0,02706018 ! bile acid transmembrane transporter activity GO:0015125 13 11 0,000 0,01285507 0,02704457 ! proteasome accessory complex GO:0022624 11 11 0,000 0,01285507 0,02702899 ! neuroblast proliferation GO:0007405 13 11 0,000 0,01285507 0,02701342 ! non-G-protein coupled 7TM receptor activity GO:0004926 14 11 0,000 0,01285507 0,02699787 ! negative regulation of neurological system process GO:0031645 13 11 0,000 0,01285507 0,02698233 ! nitric oxide mediated signal transduction GO:0007263 12 11 0,000 0,01285507 0,02696682 ! protein kinase C binding GO:0005080 11 11 0,000 0,01285507 0,02695132 ! transforming growth factor beta receptor, cytoplasmic mediator activity GO:0005072 12 11 0,000 0,01285507 0,02693584 ! male genitalia development GO:0030539 15 11 0,000 0,01285507 0,02692037 ! receptor inhibitor activity GO:0030547 12 11 0,000 0,01285507 0,02690493 GO:0048019|receptor antagonist activity, ! estrogen receptor signaling pathway GO:0030520 12 11 0,000 0,01285507 0,0268895 ! L-fucose metabolic process GO:0042354 13 11 0,000 0,01285507 0,02687409 ! palmitoyltransferase activity GO:0016409 11 11 0,000 0,01285507 0,0268587 ! arylsulfatase activity GO:0004065 12 11 0,000 0,01285507 0,02684333 ! sterol transporter activity GO:0015248 11 11 0,000 0,01285507 0,02682797 ! response to nicotine GO:0035094 13 11 0,000 0,01285507 0,02681263 ! adenylate cyclase activity GO:0004016 11 11 0,000 0,01285507 0,02679731 ! rRNA transcription GO:0009303 12 12 0,000 0,01401586 0,02920037 ! ER-associated protein catabolic process GO:0030433 14 12 0,000 0,01401586 0,0291837 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of blood pressure GO:0045777 15 12 0,000 0,01401586 0,02916706 ! superoxide anion generation GO:0042554 12 12 0,000 0,01401586 0,02915043 ! pteridine and derivative biosynthetic process GO:0042559 22 12 0,000 0,01401586 0,02913382 ! regulation of S phase GO:0033261 16 12 0,000 0,01401586 0,02911723 ! regulation of chemokine production GO:0032642 13 12 0,000 0,01401586 0,02910065 ! male meiosis GO:0007140 12 12 0,000 0,01401586 0,0290841 ! signal complex assembly GO:0007172 15 12 0,000 0,01401586 0,02906757 ! GTP metabolic process GO:0046039 14 12 0,000 0,01401586 0,02905105 ! retina morphogenesis in camera-type eye GO:0060042 16 12 0,000 0,01401586 0,02903455 ! hair follicle morphogenesis GO:0031069 14 12 0,000 0,01401586 0,02901808 ! voltage-gated sodium channel complex GO:0001518 15 12 0,000 0,01401586 0,02900162 GO:0034706|sodium channel complex, ! RNA polyadenylation GO:0043631 13 12 0,000 0,01401586 0,02898518 ! cartilage condensation GO:0001502 14 12 0,000 0,01401586 0,02896875 ! polysome GO:0005844 14 12 0,000 0,01401586 0,02895235 ! hippocampus development GO:0021766 13 12 0,000 0,01401586 0,02893596 ! lipoprotein receptor binding GO:0070325 13 12 0,000 0,01401586 0,0289196 ! beta-amyloid binding GO:0001540 12 12 0,000 0,01401586 0,02890325 ! negative regulation of endocytosis GO:0045806 15 12 0,000 0,01401586 0,02888692 ! regulation of interferon-gamma biosynthetic process GO:0045072 15 12 0,000 0,01401586 0,02887061 ! chylomicron GO:0042627 13 12 0,000 0,01401586 0,02885432 ! T cell selection GO:0045058 22 12 0,000 0,01401586 0,02883804 ! glycolipid biosynthetic process GO:0009247 13 12 0,000 0,01401586 0,02882179 ! WW domain binding GO:0050699 12 12 0,000 0,01401586 0,02880555 ! methionine metabolic process GO:0006555 14 12 0,000 0,01401586 0,02878933 ! nuclear heterochromatin GO:0005720 12 12 0,000 0,01401586 0,02877313 ! glycine metabolic process GO:0006544 14 12 0,000 0,01401586 0,02875695 ! plasma membrane organization GO:0007009 12 12 0,000 0,01401586 0,02874078 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01401586 0,02872463 ! ribonucleotide catabolic process GO:0009261 12 12 0,000 0,01401586 0,02870851 ! Golgi organization GO:0007030 15 12 0,000 0,01401586 0,0286924 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 0,01401586 0,0286763 ! mitotic spindle organization GO:0007052 13 12 0,000 0,01401586 0,02866023 ! integral to peroxisomal membrane GO:0005779 12 12 0,000 0,01401586 0,02864417 ! integral to membrane of membrane fraction GO:0000299 13 12 0,000 0,01401586 0,02862813 ! regulation of the force of heart contraction GO:0002026 13 12 0,000 0,01401586 0,02861211 ! temperature homeostasis GO:0001659 13 12 0,000 0,01401586 0,02859611 ! negative regulation of mitotic cell cycle GO:0045930 15 12 0,000 0,01401586 0,02858013 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 0,01401586 0,02856416 ! lipoprotein receptor activity GO:0030228 12 12 0,000 0,01401586 0,02854821 ! cotranslational protein targeting to membrane GO:0006613 14 12 0,000 0,01401586 0,02853228 ! axon cargo transport GO:0008088 13 12 0,000 0,01401586 0,02851637 ! regulation of phagocytosis GO:0050764 14 12 0,000 0,01401586 0,02850047 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 12 0,000 0,01401586 0,0284846 ! nucleoside triphosphate catabolic process GO:0009143 12 12 0,000 0,01401586 0,02846874 ! transcription elongation factor complex GO:0008023 12 12 0,000 0,01401586 0,02845289 ! basal lamina GO:0005605 12 12 0,000 0,01401586 0,02843707 ! regulation of interleukin-1 secretion GO:0050704 13 12 0,000 0,01401586 0,02842126 ! pancreatic ribonuclease activity GO:0004522 12 12 0,000 0,01401586 0,02840547 ! tRNA-specific ribonuclease activity GO:0004549 12 12 0,000 0,01401586 0,0283897 ! biomineral formation GO:0031214 14 12 0,000 0,01401586 0,02837394 ! water homeostasis GO:0030104 12 12 0,000 0,01401586 0,02835821 ! promoter binding GO:0010843 14 12 0,000 0,01401586 0,02834249 ! regulation of erythrocyte differentiation GO:0045646 15 12 0,000 0,01401586 0,02832679 ! intestinal absorption GO:0050892 14 12 0,000 0,01401586 0,0283111 ! pseudouridine synthase activity GO:0009982 12 12 0,000 0,01401586 0,02829543 ! oocyte differentiation GO:0009994 13 12 0,000 0,01401586 0,02827978 ! oxygen transport GO:0015671 13 12 0,000 0,01401586 0,02826415 GO:0005344|oxygen transporter activity, ! thymus development GO:0048538 13 12 0,000 0,01401586 0,02824854 ! cholesterol efflux GO:0033344 13 12 0,000 0,01401586 0,02823294 ! digestive tract morphogenesis GO:0048546 14 12 0,000 0,01401586 0,02821736 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! racemase and epimerase activity GO:0016854 13 12 0,000 0,01401586 0,02820179 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 14 12 0,000 0,01401586 0,02818625 ! tropomyosin binding GO:0005523 12 12 0,000 0,01401586 0,02817072 ! blastocyst formation GO:0001825 13 12 0,000 0,01401586 0,0281552 ! regulation of telomere maintenance GO:0032204 16 12 0,000 0,01401586 0,02813971 ! internal side of plasma membrane GO:0009898 16 12 0,000 0,01401586 0,02812423 ! mannose binding GO:0005537 13 12 0,000 0,01401586 0,02810877 ! phosphoprotein binding GO:0051219 14 12 0,000 0,01401586 0,02809332 ! defense response to fungus GO:0050832 12 12 0,000 0,01401586 0,0280779 ! embryonic placenta development GO:0001892 16 12 0,000 0,01401586 0,02806249 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 0,01401586 0,02804709 ! cell wall macromolecule metabolic process GO:0044036 15 12 0,000 0,01401586 0,02803172 ! acyl-CoA binding GO:0000062 12 12 0,000 0,01401586 0,02801636 ! cortical cytoskeleton organization GO:0030865 13 12 0,000 0,01401586 0,02800101 ! regulation of nitric-oxide synthase activity GO:0050999 12 12 0,000 0,01401586 0,02798569 ! copper ion transport GO:0006825 12 12 0,000 0,01401586 0,02797038 ! calcium ion transport into cytosol GO:0060402 19 12 0,000 0,01401586 0,02795508 ! inositol metabolic process GO:0006020 21 12 0,000 0,01401586 0,02793981 ! vesicle targeting, to, from or within Golgi GO:0048199 13 12 0,000 0,01401586 0,02792455 ! forelimb morphogenesis GO:0035136 15 12 0,000 0,01401586 0,02790931 ! protein complex disassembly GO:0043241 15 12 0,000 0,01401586 0,02789408 GO:0043624|cellular protein complex disassembly, ! ion channel inhibitor activity GO:0008200 15 12 0,000 0,01401586 0,02787887 GO:0016248|channel inhibitor activity, ! low-density lipoprotein particle GO:0034362 13 12 0,000 0,01401586 0,02786368 ! lipoprotein particle clearance GO:0034381 14 12 0,000 0,01401586 0,0278485 ! receptor signaling protein tyrosine kinase activity GO:0004716 14 12 0,000 0,01401586 0,02783334 ! endothelial cell differentiation GO:0045446 15 12 0,000 0,01401586 0,0278182 ! exosome (RNase complex) GO:0000178 13 12 0,000 0,01401586 0,02780307 ! DNA N-glycosylase activity GO:0019104 12 12 0,000 0,01401586 0,02778796 ! endoderm development GO:0007492 13 12 0,000 0,01401586 0,02777287 ! positive regulation of Ras protein signal transduction GO:0046579 25 12 0,000 0,01401586 0,02775779 ! focal adhesion formation GO:0048041 16 12 0,000 0,01401586 0,02774273 ! T cell receptor complex GO:0042101 31 12 0,000 0,01401586 0,02772768 ! cellular carbohydrate catabolic process GO:0044275 25 12 0,000 0,01401586 0,02771266 ! dicarboxylic acid transmembrane transporter activity GO:0005310 14 12 0,000 0,01401586 0,02769764 ! CoA hydrolase activity GO:0016289 14 12 0,000 0,01401586 0,02768265 ! histone acetyltransferase complex GO:0000123 14 12 0,000 0,01401586 0,02766767 ! regulation of alpha-beta T cell differentiation GO:0046637 13 12 0,000 0,01401586 0,0276527 ! alpha-beta T cell activation GO:0046631 14 12 0,000 0,01401586 0,02763776 ! retinol binding GO:0019841 12 12 0,000 0,01401586 0,02762282 ! regulation of organ growth GO:0046620 12 12 0,000 0,01401586 0,02760791 ! regulation of natural killer cell mediated immunity GO:0002715 13 12 0,000 0,01401586 0,02759301 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! vasoconstriction GO:0042310 13 12 0,000 0,01401586 0,02757813 ! histone acetylation GO:0016573 13 12 0,000 0,01401586 0,02756326 ! ribosome binding GO:0043022 13 12 0,000 0,01401586 0,02754841 ! delayed rectifier potassium channel activity GO:0005251 14 12 0,000 0,01401586 0,02753357 ! organic cation transmembrane transporter activity GO:0015101 12 12 0,000 0,01401586 0,02751876 ! phosphate transmembrane transporter activity GO:0015114 14 12 0,000 0,01401586 0,02750395 ! tissue regeneration GO:0042246 12 12 0,000 0,01401586 0,02748917 ! sulfate transmembrane transporter activity GO:0015116 13 12 0,000 0,01401586 0,02747439 ! adenylyltransferase activity GO:0070566 13 12 0,000 0,01401586 0,02745964 ! germ cell nucleus GO:0043073 14 12 0,000 0,01401586 0,0274449 ! trans-Golgi network transport vesicle membrane GO:0012510 16 12 0,000 0,01401586 0,02743018 ! hexose transmembrane transporter activity GO:0015149 12 12 0,000 0,01401586 0,02741547 ! hexosaminidase activity GO:0015929 12 12 0,000 0,01401586 0,02740078 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 0,01401586 0,0273861 ! activation of NF-kappaB-inducing kinase activity GO:0007250 14 12 0,000 0,01401586 0,02737144 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 13 12 0,000 0,01401586 0,02735679 ! dopamine metabolic process GO:0042417 15 12 0,000 0,01401586 0,02734217 ! somatic diversification of immunoglobulins GO:0016445 12 12 0,000 0,01401586 0,02732755 ! phosphoinositide 3-kinase activity GO:0035004 14 12 0,000 0,01401586 0,02731295 ! insulin-like growth factor receptor binding GO:0005159 14 12 0,000 0,01401586 0,02729837 ! bacterial binding GO:0008367 14 12 0,000 0,01401586 0,0272838 ! steroid hydroxylase activity GO:0008395 12 12 0,000 0,01401586 0,02726925 ! cardiac cell differentiation GO:0035051 16 12 0,000 0,01401586 0,02725472 ! phosphoinositide 3-kinase complex GO:0005942 14 12 0,000 0,01401586 0,0272402 ! localization within membrane GO:0051668 13 12 0,000 0,01401586 0,02722569 ! microtubule-based flagellum GO:0009434 12 12 0,000 0,01401586 0,0272112 ! axoneme part GO:0044447 12 12 0,000 0,01401586 0,02719673 ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01517534 0,02943097 ! neuron maturation GO:0042551 14 13 0,000 0,01517534 0,02941533 ! positive regulation of small GTPase mediated signal transduction GO:0051057 26 13 0,000 0,01517534 0,02939971 ! negative regulation of bone remodeling GO:0046851 15 13 0,000 0,01517534 0,0293841 ! bone remodeling GO:0046849 14 13 0,000 0,01517534 0,02936852 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01517534 0,02935294 ! regulation of receptor-mediated endocytosis GO:0048259 15 13 0,000 0,01517534 0,02933739 ! striated muscle thin filament GO:0005865 14 13 0,000 0,01517534 0,02932185 ! patterning of blood vessels GO:0001569 15 13 0,000 0,01517534 0,02930633 ! organelle fusion GO:0048284 16 13 0,000 0,01517534 0,02929082 ! palate development GO:0060021 15 13 0,000 0,01517534 0,02927533 ! induction of apoptosis via death domain receptors GO:0008625 16 13 0,000 0,01517534 0,02925986 ! arginine metabolic process GO:0006525 14 13 0,000 0,01517534 0,0292444 ! ER-Golgi intermediate compartment membrane GO:0033116 23 13 0,000 0,01517534 0,02922896 ! tyrosine metabolic process GO:0006570 15 13 0,000 0,01517534 0,02921354 ! response to retinoic acid GO:0032526 17 13 0,000 0,01517534 0,02919813 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 15 13 0,000 0,01517534 0,02918274 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lipase inhibitor activity GO:0055102 14 13 0,000 0,01517534 0,02916736 ! negative regulation of endothelial cell migration GO:0010596 15 13 0,000 0,01517534 0,029152 ! fear response GO:0042596 15 13 0,000 0,01517534 0,02913666 ! epithelial cell development GO:0002064 22 13 0,000 0,01517534 0,02912133 ! branching involved in ureteric bud morphogenesis GO:0001658 14 13 0,000 0,01517534 0,02910602 GO:0060675|ureteric bud morphogenesis, ! positive regulation of fatty acid metabolic process GO:0045923 14 13 0,000 0,01517534 0,02909073 ! protein kinase activator activity GO:0030295 17 13 0,000 0,01517534 0,02907545 ! heparan sulfate proteoglycan metabolic process GO:0030201 13 13 0,000 0,01517534 0,02906018 ! positive regulation of foam cell differentiation GO:0010744 16 13 0,000 0,01517534 0,02904494 ! protein targeting to peroxisome GO:0006625 13 13 0,000 0,01517534 0,02902971 ! NLS-bearing substrate import into nucleus GO:0006607 15 13 0,000 0,01517534 0,02901449 ! cranial nerve development GO:0021545 15 13 0,000 0,01517534 0,02899929 ! eye photoreceptor cell differentiation GO:0001754 17 13 0,000 0,01517534 0,02898411 GO:0042462|eye photoreceptor cell development, ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01517534 0,02896894 ! cerebellum morphogenesis GO:0021587 15 13 0,000 0,01517534 0,02895379 ! MHC class I receptor activity GO:0032393 20 13 0,000 0,01517534 0,02893866 ! exoribonuclease activity GO:0004532 13 13 0,000 0,01517534 0,02892354 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! intrinsic to peroxisomal membrane GO:0031231 13 13 0,000 0,01517534 0,02890843 ! COPI-coated vesicle GO:0030137 15 13 0,000 0,01517534 0,02889335 ! cofactor transporter activity GO:0051184 15 13 0,000 0,01517534 0,02887827 ! NADP metabolic process GO:0006739 15 13 0,000 0,01517534 0,02886322 ! negative regulation of macrophage differentiation GO:0045650 16 13 0,000 0,01517534 0,02884818 ! regulation of osteoclast differentiation GO:0045670 15 13 0,000 0,01517534 0,02883315 ! aromatic amino acid family catabolic process GO:0009074 13 13 0,000 0,01517534 0,02881814 ! eukaryotic cell surface binding GO:0043499 15 13 0,000 0,01517534 0,02880315 ! proximal/distal pattern formation GO:0009954 15 13 0,000 0,01517534 0,02878817 ! positive regulation of JNK cascade GO:0046330 17 13 0,000 0,01517534 0,02877321 ! positive regulation of glucose import GO:0046326 16 13 0,000 0,01517534 0,02875826 GO:0010828|positive regulation of glucose transport, ! epithelial to mesenchymal transition GO:0001837 13 13 0,000 0,01517534 0,02874333 ! ADP binding GO:0043531 15 13 0,000 0,01517534 0,02872841 ! defense response to Gram-positive bacterium GO:0050830 14 13 0,000 0,01517534 0,02871351 ! mismatched DNA binding GO:0030983 13 13 0,000 0,01517534 0,02869863 ! positive regulation of synaptic transmission GO:0050806 15 13 0,000 0,01517534 0,02868376 ! neuron fate specification GO:0048665 25 13 0,000 0,01517534 0,0286689 ! N-terminal protein amino acid modification GO:0031365 14 13 0,000 0,01517534 0,02865406 ! dicarboxylic acid transport GO:0006835 15 13 0,000 0,01517534 0,02863924 ! water transport GO:0006833 18 13 0,000 0,01517534 0,02862443 GO:0042044|fluid transport, ! replisome GO:0030894 24 13 0,000 0,01517534 0,02860964 GO:0043601|nuclear replisome, ! cytosolic calcium ion transport GO:0060401 20 13 0,000 0,01517534 0,02859486 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01517534 0,0285801 ! inorganic anion exchanger activity GO:0005452 13 13 0,000 0,01517534 0,02856535 ! negative regulation of ion transport GO:0043271 15 13 0,000 0,01517534 0,02855062 ! retinoic acid receptor binding GO:0042974 14 13 0,000 0,01517534 0,0285359 ! blood vessel remodeling GO:0001974 16 13 0,000 0,01517534 0,0285212 ! myoblast differentiation GO:0045445 15 13 0,000 0,01517534 0,02850651 ! ventral spinal cord development GO:0021517 16 13 0,000 0,01517534 0,02849184 ! prenyltransferase activity GO:0004659 15 13 0,000 0,01517534 0,02847719 ! activation of MAPKK activity GO:0000186 13 13 0,000 0,01517534 0,02846255 ! protein histidine kinase activity GO:0004673 15 13 0,000 0,01517534 0,02844792 GO:0000155|two-component sensor activity, ! cullin-RING ubiquitin ligase complex GO:0031461 13 13 0,000 0,01517534 0,02843331 ! regulation of skeletal muscle fiber development GO:0048742 16 13 0,000 0,01517534 0,02841871 ! acyl-CoA dehydrogenase activity GO:0003995 14 13 0,000 0,01517534 0,02840413 ! exocrine system development GO:0035272 14 13 0,000 0,01517534 0,02838956 ! membrane protein proteolysis GO:0033619 14 13 0,000 0,01517534 0,02837501 GO:0006509|membrane protein ectodomain proteolysis, ! organic alcohol transport GO:0015850 17 13 0,000 0,01517534 0,02836048 ! calcium ion transmembrane transporter activity GO:0015085 15 13 0,000 0,01517534 0,02834596 ! L-glutamate transport GO:0015813 14 13 0,000 0,01517534 0,02833145 GO:0015800|acidic amino acid transport, ! embryo implantation GO:0007566 17 13 0,000 0,01517534 0,02831696 ! G1/S transition checkpoint GO:0031575 14 13 0,000 0,01517534 0,02830248 ! immunoglobulin binding GO:0019865 14 13 0,000 0,01517534 0,02828802 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,01517534 0,02827357 ! regulation of T cell mediated immunity GO:0002709 17 13 0,000 0,01517534 0,02825914 ! DNA unwinding during replication GO:0006268 14 13 0,000 0,01517534 0,02824472 ! genitalia development GO:0048806 18 13 0,000 0,01517534 0,02823032 ! regulation of interleukin-8 production GO:0032677 15 13 0,000 0,01517534 0,02821593 ! regulation of interleukin-12 production GO:0032655 13 13 0,000 0,01517534 0,02820155 ! MHC class I protein binding GO:0042288 23 13 0,000 0,01517534 0,0281872 ! histone deacetylation GO:0016575 14 13 0,000 0,01517534 0,02817285 ! calcium channel regulator activity GO:0005246 16 13 0,000 0,01517534 0,02815852 ! DNA methylation GO:0006306 15 13 0,000 0,01517534 0,0281442 GO:0006305|DNA alkylation, ! mRNA splice site selection GO:0006376 17 13 0,000 0,01517534 0,0281299 ! chromatin silencing GO:0006342 13 13 0,000 0,01517534 0,02811562 ! serotonin receptor activity GO:0004993 16 13 0,000 0,01517534 0,02810135 ! monosaccharide transmembrane transporter activity GO:0015145 13 13 0,000 0,01517534 0,02808709 ! T cell homeostasis GO:0043029 14 13 0,000 0,01517534 0,02807285 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01517534 0,02805862 ! diacylglycerol kinase activity GO:0004143 15 13 0,000 0,01517534 0,0280444 ! response to gamma radiation GO:0010332 14 13 0,000 0,01517534 0,0280302 ! synaptic transmission, cholinergic GO:0007271 14 13 0,000 0,01517534 0,02801602 ! retinoic acid receptor activity GO:0003708 15 13 0,000 0,01517534 0,02800185 ! purine base metabolic process GO:0006144 15 13 0,000 0,01517534 0,02798769 ! cAMP binding GO:0030552 15 13 0,000 0,01517534 0,02797355 ! biogenic amine catabolic process GO:0042402 14 13 0,000 0,01517534 0,02795942 ! negative regulation of BMP signaling pathway GO:0030514 14 13 0,000 0,01517534 0,02794531 ! regulation of axon extension GO:0030516 16 13 0,000 0,01517534 0,02793121 ! drug transporter activity GO:0015238 14 13 0,000 0,01517534 0,02791712 ! regulation of NF-kappaB import into nucleus GO:0042345 14 13 0,000 0,01517534 0,02790305 ! calcium-activated potassium channel activity GO:0015269 15 13 0,000 0,01517534 0,02788899 ! response to cold GO:0009409 13 13 0,000 0,01517534 0,02787495 ! cadherin binding GO:0045296 16 13 0,000 0,01517534 0,02786092 ! nucleolar part GO:0044452 13 13 0,000 0,01517534 0,02784691 ! tRNA modification GO:0006400 14 14 0,000 0,01633353 0,02995712 ! cis-Golgi network GO:0005801 16 14 0,000 0,01633353 0,02994206 ! negative regulation of hormone secretion GO:0046888 14 14 0,000 0,01633353 0,02992702 ! 'de novo' protein folding GO:0006458 14 14 0,000 0,01633353 0,029912 ! organellar large ribosomal subunit GO:0000315 15 14 0,000 0,01633353 0,02989699 GO:0005762|mitochondrial large ribosomal subunit, ! phosphoinositide phosphorylation GO:0046854 18 14 0,000 0,01633353 0,029882 ! peroxisomal transport GO:0043574 14 14 0,000 0,01633353 0,02986702 ! cardiac muscle contraction GO:0060048 15 14 0,000 0,01633353 0,02985206 ! dopamine receptor signaling pathway GO:0007212 19 14 0,000 0,01633353 0,02983711 ! mechanoreceptor differentiation GO:0042490 16 14 0,000 0,01633353 0,02982217 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 18 14 0,000 0,01633353 0,02980726 ! pseudouridine synthesis GO:0001522 14 14 0,000 0,01633353 0,02979235 ! positive regulation of cell growth GO:0030307 15 14 0,000 0,01633353 0,02977746 ! caspase activator activity GO:0008656 16 14 0,000 0,01633353 0,02976259 ! MHC class II protein complex GO:0042613 19 14 0,000 0,01633353 0,02974773 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01633353 0,02973289 ! cAMP-dependent protein kinase regulator activity GO:0008603 17 14 0,000 0,01633353 0,02971806 ! cation:cation antiporter activity GO:0015491 14 14 0,000 0,01633353 0,02970324 ! glycoprotein catabolic process GO:0006516 16 14 0,000 0,01633353 0,02968844 ! protein polyubiquitination GO:0000209 15 14 0,000 0,01633353 0,02967366 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 34 14 0,000 0,01633353 0,02965889 ! negative regulation of microtubule depolymerization GO:0007026 16 14 0,000 0,01633353 0,02964413 GO:0031114|regulation of microtubule depolymerization, ! cell-cell junction assembly GO:0007043 15 14 0,000 0,01633353 0,02962939 ! response to vitamin A GO:0033189 18 14 0,000 0,01633353 0,02961466 ! actin filament bundle formation GO:0051017 16 14 0,000 0,01633353 0,02959995 ! regulation of lipoprotein lipase activity GO:0051004 15 14 0,000 0,01633353 0,02958526 ! plasma membrane fusion GO:0045026 15 14 0,000 0,01633353 0,02957057 ! purine nucleoside monophosphate metabolic process GO:0009126 15 14 0,000 0,01633353 0,02955591 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 16 14 0,000 0,01633353 0,02954125 ! protein export from nucleus GO:0006611 14 14 0,000 0,01633353 0,02952661 ! presynaptic membrane GO:0042734 14 14 0,000 0,01633353 0,02951199 ! negative regulation of immune response GO:0050777 21 14 0,000 0,01633353 0,02949738 ! gastrulation with mouth forming second GO:0001702 15 14 0,000 0,01633353 0,02948278 ! neural crest cell migration GO:0001755 15 14 0,000 0,01633353 0,0294682 ! anaphase-promoting complex GO:0005680 17 14 0,000 0,01633353 0,02945364 ! positive regulation of oxidoreductase activity GO:0051353 14 14 0,000 0,01633353 0,02943908 ! negative regulation of protein secretion GO:0050709 17 14 0,000 0,01633353 0,02942455 ! cofactor transport GO:0051181 16 14 0,000 0,01633353 0,02941002 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,01633353 0,02939551 ! protein-chromophore linkage GO:0018298 16 14 0,000 0,01633353 0,02938102 ! cobalt ion binding GO:0050897 14 14 0,000 0,01633353 0,02936654 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01633353 0,02935207 ! positive regulation of transmission of nerve impulse GO:0051971 16 14 0,000 0,01633353 0,02933762 ! aspartate family amino acid biosynthetic process GO:0009067 17 14 0,000 0,01633353 0,02932318 ! gas transport GO:0015669 15 14 0,000 0,01633353 0,02930876 ! pyridine nucleotide biosynthetic process GO:0019363 15 14 0,000 0,01633353 0,02929435 ! heme biosynthetic process GO:0006783 14 14 0,000 0,01633353 0,02927995 ! release of cytochrome c from mitochondria GO:0001836 26 14 0,000 0,01633353 0,02926557 ! cerebellar cortex development GO:0021695 16 14 0,000 0,01633353 0,02925121 ! insulin secretion GO:0030073 17 14 0,000 0,01633353 0,02923685 ! tRNA binding GO:0000049 16 14 0,000 0,01633353 0,02922251 ! positive regulation of cell killing GO:0031343 16 14 0,000 0,01633353 0,02920819 ! positive regulation of protein complex assembly GO:0031334 14 14 0,000 0,01633353 0,02919388 ! phosphatidylinositol metabolic process GO:0046488 15 14 0,000 0,01633353 0,02917958 ! regulation of neuronal synaptic plasticity GO:0048168 24 14 0,000 0,01633353 0,0291653 ! MAP kinase activity GO:0004707 16 14 0,000 0,01633353 0,02915103 ! cytokine biosynthetic process GO:0042089 14 14 0,000 0,01633353 0,02913678 ! mannosyltransferase activity GO:0000030 14 14 0,000 0,01633353 0,02912253 ! isoprenoid biosynthetic process GO:0008299 17 14 0,000 0,01633353 0,02910831 ! C-C chemokine binding GO:0019957 15 14 0,000 0,01633353 0,02909409 GO:0016493|C-C chemokine receptor activity, ! cardiac muscle tissue development GO:0048738 16 14 0,000 0,01633353 0,0290799 ! complement activation, alternative pathway GO:0006957 14 14 0,000 0,01633353 0,02906571 ! response to osmotic stress GO:0006970 17 14 0,000 0,01633353 0,02905154 ! fructose metabolic process GO:0006000 15 14 0,000 0,01633353 0,02903738 ! telomeric DNA binding GO:0042162 17 14 0,000 0,01633353 0,02902324 ! monoamine transport GO:0015844 15 14 0,000 0,01633353 0,02900911 ! regulation of pathway-restricted SMAD protein phosphorylation GO:0060393 14 14 0,000 0,01633353 0,02899499 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,01633353 0,02898089 ! dendritic spine GO:0043197 15 14 0,000 0,01633353 0,0289668 ! stem cell development GO:0048864 14 14 0,000 0,01633353 0,02895272 GO:0019827|stem cell maintenance, ! regulation of alpha-beta T cell activation GO:0046634 15 14 0,000 0,01633353 0,02893866 ! regulation of insulin receptor signaling pathway GO:0046626 17 14 0,000 0,01633353 0,02892461 ! regulation of cytokine production during immune response GO:0002718 15 14 0,000 0,01633353 0,02891058 ! positive regulation of protein import into nucleus GO:0042307 16 14 0,000 0,01633353 0,02889656 ! regulation of cellular pH GO:0030641 14 14 0,000 0,01633353 0,02888255 ! regulation of monooxygenase activity GO:0032768 14 14 0,000 0,01633353 0,02886856 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,01633353 0,02885458 ! sarcoplasmic reticulum membrane GO:0033017 16 14 0,000 0,01633353 0,02884061 ! detection of biotic stimulus GO:0009595 16 14 0,000 0,01633353 0,02882666 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 16 14 0,000 0,01633353 0,02881272 ! mannosidase activity GO:0015923 19 14 0,000 0,01633353 0,02879879 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 17 14 0,000 0,01633353 0,02878488 ! negative regulation of tissue remodeling GO:0034104 16 14 0,000 0,01633353 0,02877098 ! positive regulation of bone mineralization GO:0030501 14 14 0,000 0,01633353 0,0287571 ! neuromuscular synaptic transmission GO:0007274 15 14 0,000 0,01633353 0,02874322 ! regulation of immunoglobulin production GO:0002637 15 14 0,000 0,01633353 0,02872937 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,01633353 0,02871552 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 16 14 0,000 0,01633353 0,02870169 ! fucosyltransferase activity GO:0008417 16 14 0,000 0,01633353 0,02868787 ! sperm-egg recognition GO:0035036 17 14 0,000 0,01633353 0,02867406 GO:0007339|binding of sperm to zona pellucida, ! defense response to virus GO:0051607 21 14 0,000 0,01633353 0,02866027 ! SWI/SNF-type complex GO:0070603 16 14 0,000 0,01633353 0,02864649 GO:0016514|SWI/SNF complex, ! aldo-keto reductase activity GO:0004033 15 14 0,000 0,01633353 0,02863273 ! positive regulation of translation GO:0045727 17 15 0,000 0,01749041 0,03064602 ! nuclear replication fork GO:0043596 26 15 0,000 0,01749041 0,03063131 ! transferase activity, transferring amino-acyl groups GO:0016755 15 15 0,000 0,01749041 0,03061661 ! 2'-deoxyribonucleotide metabolic process GO:0009394 16 15 0,000 0,01749041 0,03060193 GO:0019692|deoxyribose phosphate metabolic process, ! phospholipid catabolic process GO:0009395 26 15 0,000 0,01749041 0,03058726 ! endothelial cell migration GO:0043542 16 15 0,000 0,01749041 0,0305726 ! lipid phosphorylation GO:0046834 19 15 0,000 0,01749041 0,03055796 ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,01749041 0,03054333 ! response to vitamin GO:0033273 19 15 0,000 0,01749041 0,03052872 ! gene silencing by RNA GO:0031047 17 15 0,000 0,01749041 0,03051412 ! striated muscle thick filament GO:0005863 16 15 0,000 0,01749041 0,03049953 GO:0032982|myosin filament, ! cellular response to hydrogen peroxide GO:0070301 15 15 0,000 0,01749041 0,03048496 GO:0042744|hydrogen peroxide catabolic process, ! endocrine pancreas development GO:0031018 16 15 0,000 0,01749041 0,0304704 ! regulation of interleukin-2 biosynthetic process GO:0045076 15 15 0,000 0,01749041 0,03045585 ! glutamate metabolic process GO:0006536 17 15 0,000 0,01749041 0,03044132 ! pituitary gland development GO:0021983 16 15 0,000 0,01749041 0,03042681 ! cholesterol binding GO:0015485 15 15 0,000 0,01749041 0,03041231 ! NAD metabolic process GO:0019674 17 15 0,000 0,01749041 0,03039782 ! protease binding GO:0002020 20 15 0,000 0,01749041 0,03038334 ! regulation of heart rate GO:0002027 20 15 0,000 0,01749041 0,03036888 ! actin filament bundle GO:0032432 18 15 0,000 0,01749041 0,03035443 GO:0001725|stress fiber, ! Golgi cisterna GO:0031985 17 15 0,000 0,01749041 0,03034 ! regulation of exocytosis GO:0017157 16 15 0,000 0,01749041 0,03032558 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,01749041 0,03031117 ! embryonic digit morphogenesis GO:0042733 17 15 0,000 0,01749041 0,03029678 ! positive regulation of biomineral formation GO:0070169 15 15 0,000 0,01749041 0,0302824 ! prostaglandin metabolic process GO:0006693 15 15 0,000 0,01749041 0,03026803 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 20 15 0,000 0,01749041 0,03025368 ! neuron recognition GO:0008038 18 15 0,000 0,01749041 0,03023934 ! hindbrain morphogenesis GO:0021575 18 15 0,000 0,01749041 0,03022502 ! filopodium GO:0030175 17 15 0,000 0,01749041 0,03021071 ! negative regulation of blood coagulation GO:0030195 18 15 0,000 0,01749041 0,03019641 ! folic acid and derivative metabolic process GO:0006760 15 15 0,000 0,01749041 0,03018213 ! positive regulation of neuron differentiation GO:0045666 27 15 0,000 0,01749041 0,03016786 ! peptide hormone binding GO:0017046 16 15 0,000 0,01749041 0,0301536 ! regulation of ATPase activity GO:0043462 17 15 0,000 0,01749041 0,03013936 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 16 15 0,000 0,01749041 0,03012513 ! regulation of leukocyte mediated cytotoxicity GO:0001910 21 15 0,000 0,01749041 0,03011091 ! acid-thiol ligase activity GO:0016878 16 15 0,000 0,01749041 0,03009671 ! aromatic compound biosynthetic process GO:0019438 25 15 0,000 0,01749041 0,03008252 ! positive regulation of calcium ion transport GO:0051928 20 15 0,000 0,01749041 0,03006834 ! dystrophin-associated glycoprotein complex GO:0016010 17 15 0,000 0,01749041 0,03005418 ! RNA 3'-end processing GO:0031123 16 15 0,000 0,01749041 0,03004003 ! developmental induction GO:0031128 17 15 0,000 0,01749041 0,03002589 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 17 15 0,000 0,01749041 0,03001177 ! protein import into nucleus, docking GO:0000059 15 15 0,000 0,01749041 0,02999766 ! regulation of skeletal muscle tissue development GO:0048641 18 15 0,000 0,01749041 0,02998356 ! lactation GO:0007595 17 15 0,000 0,01749041 0,02996948 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 16 15 0,000 0,01749041 0,02995541 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01749041 0,02994135 ! phosphatidylcholine metabolic process GO:0046470 16 15 0,000 0,01749041 0,02992731 ! regulation of cell-cell adhesion GO:0022407 18 15 0,000 0,01749041 0,02991328 ! sulfate transport GO:0008272 16 15 0,000 0,01749041 0,02989926 ! hindlimb morphogenesis GO:0035137 17 15 0,000 0,01749041 0,02988525 ! bile acid metabolic process GO:0008206 17 15 0,000 0,01749041 0,02987126 ! very-low-density lipoprotein particle GO:0034361 16 15 0,000 0,01749041 0,02985728 GO:0034385|triglyceride-rich lipoprotein particle, ! adult walking behavior GO:0007628 19 15 0,000 0,01749041 0,02984332 ! 2 iron, 2 sulfur cluster binding GO:0051537 16 15 0,000 0,01749041 0,02982937 ! heart looping GO:0001947 18 15 0,000 0,01749041 0,02981543 ! protein kinase C activity GO:0004697 17 15 0,000 0,01749041 0,0298015 ! oligodendrocyte differentiation GO:0048709 15 15 0,000 0,01749041 0,02978759 ! regulation of striated muscle contraction GO:0006942 18 15 0,000 0,01749041 0,02977369 ! pigmentation during development GO:0048066 17 15 0,000 0,01749041 0,0297598 ! cytokine metabolic process GO:0042107 15 15 0,000 0,01749041 0,02974593 ! vesicle coating GO:0006901 17 15 0,000 0,01749041 0,02973207 ! disulfide oxidoreductase activity GO:0015036 16 15 0,000 0,01749041 0,02971822 ! neutral amino acid transport GO:0015804 18 15 0,000 0,01749041 0,02970438 ! L-amino acid transport GO:0015807 16 15 0,000 0,01749041 0,02969056 ! microfilament motor activity GO:0000146 15 15 0,000 0,01749041 0,02967675 ! carbonate dehydratase activity GO:0004089 18 15 0,000 0,01749041 0,02966295 ! regulation of vasodilation GO:0042312 25 15 0,000 0,01749041 0,02964917 ! DNA replication initiation GO:0006270 15 15 0,000 0,01749041 0,0296354 ! taste receptor activity GO:0008527 15 15 0,000 0,01749041 0,02962164 ! cellular pigmentation GO:0033059 16 15 0,000 0,01749041 0,0296079 ! voltage-gated chloride channel activity GO:0005247 18 15 0,000 0,01749041 0,02959416 ! voltage-gated sodium channel activity GO:0005248 18 15 0,000 0,01749041 0,02958044 ! long-chain fatty acid transport GO:0015909 17 15 0,000 0,01749041 0,02956674 ! positive regulation of neurological system process GO:0031646 18 15 0,000 0,01749041 0,02955304 ! nerve-nerve synaptic transmission GO:0007270 17 15 0,000 0,01749041 0,02953936 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 17 15 0,000 0,01749041 0,02952569 ! ion gated channel activity GO:0022839 17 15 0,000 0,01749041 0,02951203 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 15 15 0,000 0,01749041 0,02949839 ! receptor activator activity GO:0030546 17 15 0,000 0,01749041 0,02948476 ! protein transmembrane transporter activity GO:0008320 16 15 0,000 0,01749041 0,02947114 ! negative regulation of mast cell proliferation GO:0070667 16 15 0,000 0,01749041 0,02945753 GO:0042130|negative regulation of T cell proliferation, ! acylglycerol O-acyltransferase activity GO:0016411 16 15 0,000 0,01749041 0,02944394 ! triacylglycerol lipase activity GO:0004806 16 15 0,000 0,01749041 0,02943036 ! peptide hormone processing GO:0016486 19 15 0,000 0,01749041 0,02941679 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,01749041 0,02940323 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 19 16 0,000 0,01864599 0,03133146 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,01864599 0,03131703 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 18 16 0,000 0,01864599 0,03130262 ! heterophilic cell adhesion GO:0007157 17 16 0,000 0,01864599 0,03128822 ! gamma-aminobutyric acid signaling pathway GO:0007214 17 16 0,000 0,01864599 0,03127383 ! kinesin complex GO:0005871 16 16 0,000 0,01864599 0,03125946 ! photoreceptor cell development GO:0042461 22 16 0,000 0,01864599 0,0312451 GO:0046530|photoreceptor cell differentiation, ! negative regulation of gene expression, epigenetic GO:0045814 16 16 0,000 0,01864599 0,03123076 ! mitotic chromosome condensation GO:0007076 17 16 0,000 0,01864599 0,03121642 ! negative regulation of epithelial cell proliferation GO:0050680 18 16 0,000 0,01864599 0,03120211 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 16 0,000 0,01864599 0,0311878 ! DNA duplex unwinding GO:0032508 17 16 0,000 0,01864599 0,03117351 GO:0032392|DNA geometric change, ! cerebral cortex development GO:0021987 16 16 0,000 0,01864599 0,03115923 ! lysosomal transport GO:0007041 16 16 0,000 0,01864599 0,03114496 ! transforming growth factor beta receptor activity GO:0005024 18 16 0,000 0,01864599 0,0311307 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! rough endoplasmic reticulum GO:0005791 16 16 0,000 0,01864599 0,03111646 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 16 16 0,000 0,01864599 0,03110224 ! small nucleolar ribonucleoprotein complex GO:0005732 16 16 0,000 0,01864599 0,03108802 ! myofibril assembly GO:0030239 17 16 0,000 0,01864599 0,03107382 GO:0055002|striated muscle cell development, ! receptor signaling complex scaffold activity GO:0030159 19 16 0,000 0,01864599 0,03105963 ! negative regulation of inflammatory response GO:0050728 17 16 0,000 0,01864599 0,03104545 ! clathrin vesicle coat GO:0030125 20 16 0,000 0,01864599 0,03103129 ! endodeoxyribonuclease activity GO:0004520 43 16 0,000 0,01864599 0,03101714 ! sphingolipid catabolic process GO:0030149 18 16 0,000 0,01864599 0,031003 GO:0046466|membrane lipid catabolic process, ! natural killer cell activation GO:0030101 17 16 0,000 0,01864599 0,03098888 ! steroid catabolic process GO:0006706 18 16 0,000 0,01864599 0,03097477 ! branched chain family amino acid metabolic process GO:0009081 18 16 0,000 0,01864599 0,03096067 ! cell-cell recognition GO:0009988 19 16 0,000 0,01864599 0,03094658 ! somatic diversification of immune receptors GO:0002200 17 16 0,000 0,01864599 0,03093251 ! spleen development GO:0048536 19 16 0,000 0,01864599 0,03091845 ! lymphocyte homeostasis GO:0002260 17 16 0,000 0,01864599 0,0309044 ! regulation of fatty acid oxidation GO:0046320 19 16 0,000 0,01864599 0,03089037 ! neural tube closure GO:0001843 19 16 0,000 0,01864599 0,03087635 GO:0060606|tube closure, ! antigen receptor-mediated signaling pathway GO:0050851 22 16 0,000 0,01864599 0,03086234 ! regulation of glucose metabolic process GO:0010906 18 16 0,000 0,01864599 0,03084834 ! regulation of lipid catabolic process GO:0050994 18 16 0,000 0,01864599 0,03083436 ! viral genome replication GO:0019079 16 16 0,000 0,01864599 0,03082038 ! regulation of neurotransmitter transport GO:0051588 19 16 0,000 0,01864599 0,03080643 ! memory GO:0007613 18 16 0,000 0,01864599 0,03079248 ! regulation of carbohydrate biosynthetic process GO:0043255 17 16 0,000 0,01864599 0,03077855 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01864599 0,03076463 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 18 16 0,000 0,01864599 0,03075072 ! glycoprotein binding GO:0001948 19 16 0,000 0,01864599 0,03073682 ! negative regulation of endothelial cell proliferation GO:0001937 17 16 0,000 0,01864599 0,03072294 ! syntaxin binding GO:0019905 18 16 0,000 0,01864599 0,03070907 ! myosin binding GO:0017022 17 16 0,000 0,01864599 0,03069521 ! epidermis morphogenesis GO:0048730 18 16 0,000 0,01864599 0,03068137 ! fucose metabolic process GO:0006004 18 16 0,000 0,01864599 0,03066753 ! actin polymerization or depolymerization GO:0008154 18 16 0,000 0,01864599 0,03065371 ! membrane budding GO:0006900 18 16 0,000 0,01864599 0,0306399 ! preassembly of GPI anchor in ER membrane GO:0016254 18 16 0,000 0,01864599 0,03062611 ! intermediate filament cytoskeleton organization GO:0045104 16 16 0,000 0,01864599 0,03061233 ! behavioral interaction between organisms GO:0051705 19 16 0,000 0,01864599 0,03059856 ! nucleotide-excision repair, DNA gap filling GO:0006297 19 16 0,000 0,01864599 0,0305848 ! anchored to plasma membrane GO:0046658 20 16 0,000 0,01864599 0,03057105 ! calcium activated cation channel activity GO:0005227 18 16 0,000 0,01864599 0,03055732 ! DNA fragmentation involved in apoptosis GO:0006309 18 16 0,000 0,01864599 0,0305436 ! apoptotic protease activator activity GO:0016505 18 16 0,000 0,01864599 0,03052989 ! sulfuric ester hydrolase activity GO:0008484 18 16 0,000 0,01864599 0,03051619 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 18 16 0,000 0,01864599 0,03050251 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,01864599 0,03048883 ! RNA polymerase II transcription mediator activity GO:0016455 19 16 0,000 0,01864599 0,03047517 ! axoneme GO:0005930 16 16 0,000 0,01864599 0,03046153 ! negative regulation of homeostatic process GO:0032845 19 16 0,000 0,01864599 0,03044789 ! anion exchanger activity GO:0015380 17 17 0,000 0,01980028 0,03231831 ! positive regulation of hormone secretion GO:0046887 19 17 0,000 0,01980028 0,03230386 ! skin development GO:0043588 20 17 0,000 0,01980028 0,03228942 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 17 17 0,000 0,01980028 0,03227499 ! transcription from RNA polymerase III promoter GO:0006383 18 17 0,000 0,01980028 0,03226058 ! glial cell development GO:0021782 17 17 0,000 0,01980028 0,03224617 ! limbic system development GO:0021761 18 17 0,000 0,01980028 0,03223178 ! protein phosphatase type 2A regulator activity GO:0008601 19 17 0,000 0,01980028 0,03221741 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 17 0,000 0,01980028 0,03220304 ! ephrin receptor activity GO:0005003 21 17 0,000 0,01980028 0,03218869 ! acetylcholine receptor activity GO:0015464 18 17 0,000 0,01980028 0,03217436 ! glutamine metabolic process GO:0006541 26 17 0,000 0,01980028 0,03216003 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 21 17 0,000 0,01980028 0,03214572 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 37 17 0,000 0,01980028 0,03213142 ! signal sequence binding GO:0005048 18 17 0,000 0,01980028 0,03211713 ! cell-substrate junction assembly GO:0007044 21 17 0,000 0,01980028 0,03210286 ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,01980028 0,0320886 ! organelle subcompartment GO:0031984 19 17 0,000 0,01980028 0,03207435 ! regulation of vasoconstriction GO:0019229 21 17 0,000 0,01980028 0,03206011 ! membrane depolarization GO:0051899 19 17 0,000 0,01980028 0,03204589 ! oogenesis GO:0048477 20 17 0,000 0,01980028 0,03203168 ! nuclear outer membrane GO:0005640 21 17 0,000 0,01980028 0,03201748 ! regulation of immunoglobulin mediated immune response GO:0002889 18 17 0,000 0,01980028 0,03200329 GO:0002712|regulation of B cell mediated immunity, ! immunoglobulin production GO:0002377 21 17 0,000 0,01980028 0,03198912 GO:0002440|production of molecular mediator of immune response, ! positive regulation of cellular carbohydrate metabolic process GO:0010676 18 17 0,000 0,01980028 0,03197496 ! positive regulation of macrophage differentiation GO:0045651 21 17 0,000 0,01980028 0,03196081 ! organic cation transport GO:0015695 17 17 0,000 0,01980028 0,03194667 ! porphyrin biosynthetic process GO:0006779 17 17 0,000 0,01980028 0,03193255 GO:0033014|tetrapyrrole biosynthetic process, ! phosphatidylinositol binding GO:0005545 21 17 0,000 0,01980028 0,03191844 ! hyaluronic acid binding GO:0005540 19 17 0,000 0,01980028 0,03190434 ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 17 0,000 0,01980028 0,03189026 ! negative regulation of coagulation GO:0050819 20 17 0,000 0,01980028 0,03187618 ! cellular monovalent inorganic cation homeostasis GO:0030004 18 17 0,000 0,01980028 0,03186212 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 17 0,000 0,01980028 0,03184807 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 17 0,000 0,01980028 0,03183404 ! negative regulation of defense response GO:0031348 19 17 0,000 0,01980028 0,03182001 ! lipid localization GO:0010876 19 17 0,000 0,01980028 0,031806 GO:0019915|lipid storage, ! tube lumen formation GO:0035148 20 17 0,000 0,01980028 0,031792 ! negative regulation of cytokine biosynthetic process GO:0042036 18 17 0,000 0,01980028 0,03177802 ! regulation of systemic arterial blood pressure by hormone GO:0001990 17 17 0,000 0,01980028 0,03176404 GO:0050886|endocrine process, ! MAP kinase kinase kinase activity GO:0004709 19 17 0,000 0,01980028 0,03175008 ! negative regulation of protein amino acid phosphorylation GO:0001933 19 17 0,000 0,01980028 0,03173613 ! protein phosphatase type 2A complex GO:0000159 21 17 0,000 0,01980028 0,03172219 ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 22 17 0,000 0,01980028 0,03170827 ! response to hexose stimulus GO:0009746 20 17 0,000 0,01980028 0,03169435 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! transmembrane receptor protein phosphatase activity GO:0019198 24 17 0,000 0,01980028 0,03168045 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! AMP binding GO:0016208 19 17 0,000 0,01980028 0,03166656 ! UDP-galactosyltransferase activity GO:0035250 19 17 0,000 0,01980028 0,03165269 ! receptor metabolic process GO:0043112 20 17 0,000 0,01980028 0,03163882 ! neurotransmitter metabolic process GO:0042133 20 17 0,000 0,01980028 0,03162497 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 23 17 0,000 0,01980028 0,03161113 ! alcohol binding GO:0043178 20 17 0,000 0,01980028 0,0315973 ! T cell differentiation in the thymus GO:0033077 28 17 0,000 0,01980028 0,03158348 ! visual learning GO:0008542 31 17 0,000 0,01980028 0,03156968 ! structural constituent of eye lens GO:0005212 20 17 0,000 0,01980028 0,03155589 ! cellular amino acid derivative catabolic process GO:0042219 19 17 0,000 0,01980028 0,03154211 ! neutrophil chemotaxis GO:0030593 17 17 0,000 0,01980028 0,03152834 ! protein localization in mitochondrion GO:0070585 19 17 0,000 0,01980028 0,03151458 GO:0006626|protein targeting to mitochondrion, ! aspartic-type endopeptidase activity GO:0004190 18 17 0,000 0,01980028 0,03150084 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 19 17 0,000 0,01980028 0,03148711 ! proton-transporting ATP synthase complex GO:0045259 17 17 0,000 0,01980028 0,03147339 ! translation elongation factor activity GO:0003746 19 17 0,000 0,01980028 0,03145968 ! histone binding GO:0042393 26 17 0,000 0,01980028 0,03144599 ! cilium assembly GO:0042384 18 17 0,000 0,01980028 0,0314323 ! transforming growth factor beta receptor binding GO:0005160 19 17 0,000 0,01980028 0,03141863 ! positive regulation of homeostatic process GO:0032846 23 17 0,000 0,01980028 0,03140497 ! solute:hydrogen antiporter activity GO:0015299 18 17 0,000 0,01980028 0,03139132 ! protein secretion GO:0009306 19 18 0,000 0,02095327 0,03320484 ! positive regulation of cell size GO:0045793 19 18 0,000 0,02095327 0,03319042 ! positive regulation of ossification GO:0045778 19 18 0,000 0,02095327 0,03317602 ! positive regulation of angiogenesis GO:0045766 19 18 0,000 0,02095327 0,03316162 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,02095327 0,03314724 GO:0005763|mitochondrial small ribosomal subunit, ! protein amino acid deacetylation GO:0006476 19 18 0,000 0,02095327 0,03313287 ! protein amino acid acetylation GO:0006473 21 18 0,000 0,02095327 0,03311852 ! positive regulation of nucleocytoplasmic transport GO:0046824 20 18 0,000 0,02095327 0,03310418 ! cAMP metabolic process GO:0046058 18 18 0,000 0,02095327 0,03308984 ! regulation of muscle cell differentiation GO:0051147 21 18 0,000 0,02095327 0,03307553 ! cornified envelope GO:0001533 22 18 0,000 0,02095327 0,03306122 ! retinoid metabolic process GO:0001523 19 18 0,000 0,02095327 0,03304693 GO:0016101|diterpenoid metabolic process, ! actomyosin GO:0042641 21 18 0,000 0,02095327 0,03303265 ! positive regulation of proteolysis GO:0045862 20 18 0,000 0,02095327 0,03301838 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 18 0,000 0,02095327 0,03300412 ! calcium-dependent protein binding GO:0048306 20 18 0,000 0,02095327 0,03298988 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 18 18 0,000 0,02095327 0,03297564 ! proton-transporting V-type ATPase complex GO:0033176 18 18 0,000 0,02095327 0,03296142 ! pyrimidine ribonucleoside metabolic process GO:0046131 23 18 0,000 0,02095327 0,03294722 ! regulation of ion transmembrane transporter activity GO:0032412 21 18 0,000 0,02095327 0,03293302 ! positive regulation of carbohydrate metabolic process GO:0045913 19 18 0,000 0,02095327 0,03291884 ! primary neural tube formation GO:0014020 21 18 0,000 0,02095327 0,03290467 ! recycling endosome GO:0055037 22 18 0,000 0,02095327 0,03289051 ! muscle cell development GO:0055001 20 18 0,000 0,02095327 0,03287636 ! kinase activator activity GO:0019209 22 18 0,000 0,02095327 0,03286223 ! positive regulation of T cell differentiation GO:0045582 28 18 0,000 0,02095327 0,03284811 ! cerebellum development GO:0021549 20 18 0,000 0,02095327 0,032834 ! positive regulation of multicellular organism growth GO:0040018 19 18 0,000 0,02095327 0,0328199 ! somitogenesis GO:0001756 20 18 0,000 0,02095327 0,03280581 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,02095327 0,03279174 ! low-density lipoprotein binding GO:0030169 19 18 0,000 0,02095327 0,03277768 ! positive regulation of cytokine secretion GO:0050715 21 18 0,000 0,02095327 0,03276363 ! negative regulation of intracellular transport GO:0032387 20 18 0,000 0,02095327 0,03274959 ! glutamine family amino acid catabolic process GO:0009065 21 18 0,000 0,02095327 0,03273556 ! basal plasma membrane GO:0009925 21 18 0,000 0,02095327 0,03272155 GO:0045178|basal part of cell, ! vitamin D receptor binding GO:0042809 20 18 0,000 0,02095327 0,03270755 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 19 18 0,000 0,02095327 0,03269356 ! embryonic organ morphogenesis GO:0048562 22 18 0,000 0,02095327 0,03267958 ! regulation of cell killing GO:0031341 24 18 0,000 0,02095327 0,03266562 ! positive regulation of cellular catabolic process GO:0031331 20 18 0,000 0,02095327 0,03265166 ! nuclear chromosome, telomeric region GO:0000784 30 18 0,000 0,02095327 0,03263772 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 19 18 0,000 0,02095327 0,03262379 ! intra-Golgi vesicle-mediated transport GO:0006891 20 18 0,000 0,02095327 0,03260987 ! protein complex scaffold GO:0032947 22 18 0,000 0,02095327 0,03259597 ! SNAP receptor activity GO:0005484 21 18 0,000 0,02095327 0,03258207 ! dendrite development GO:0016358 22 18 0,000 0,02095327 0,03256819 ! cell differentiation in spinal cord GO:0021515 21 18 0,000 0,02095327 0,03255432 ! inactivation of MAPK activity GO:0000188 20 18 0,000 0,02095327 0,03254046 ! calmodulin-dependent protein kinase activity GO:0004683 20 18 0,000 0,02095327 0,03252661 ! D-ribose metabolic process GO:0006014 19 18 0,000 0,02095327 0,03251278 ! glucuronosyltransferase activity GO:0015020 18 18 0,000 0,02095327 0,03249895 ! coreceptor activity GO:0015026 28 18 0,000 0,02095327 0,03248514 ! response to fungus GO:0009620 18 18 0,000 0,02095327 0,03247134 ! stem cell differentiation GO:0048863 18 18 0,000 0,02095327 0,03245755 ! intermediate filament-based process GO:0045103 18 18 0,000 0,02095327 0,03244378 ! heart process GO:0003015 19 18 0,000 0,02095327 0,03243001 GO:0060047|heart contraction, ! mismatch repair GO:0006298 28 18 0,000 0,02095327 0,03241626 ! vasodilation GO:0042311 20 18 0,000 0,02095327 0,03240252 ! transport vesicle membrane GO:0030658 23 18 0,000 0,02095327 0,03238879 ! MHC protein binding GO:0042287 30 18 0,000 0,02095327 0,03237507 ! inward rectifier potassium channel activity GO:0005242 22 18 0,000 0,02095327 0,03236136 ! chloride transmembrane transporter activity GO:0015108 19 18 0,000 0,02095327 0,03234767 ! bicarbonate transmembrane transporter activity GO:0015106 18 18 0,000 0,02095327 0,03233399 ! ionotropic glutamate receptor activity GO:0004970 22 18 0,000 0,02095327 0,03232031 ! cell-cell adherens junction GO:0005913 20 18 0,000 0,02095327 0,03230665 ! negative regulation of leukocyte proliferation GO:0070664 20 18 0,000 0,02095327 0,032293 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! ubiquitin-specific protease activity GO:0004843 19 18 0,000 0,02095327 0,03227937 ! ATP-dependent RNA helicase activity GO:0004004 28 18 0,000 0,02095327 0,03226574 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 24 19 0,000 0,02210497 0,03402486 ! pteridine and derivative metabolic process GO:0042558 29 19 0,000 0,02210497 0,03401051 ! proteasome core complex GO:0005839 20 19 0,000 0,02210497 0,03399618 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 22 19 0,000 0,02210497 0,03398185 ! anion:anion antiporter activity GO:0015301 19 19 0,000 0,02210497 0,03396754 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 24 19 0,000 0,02210497 0,03395323 ! regulation of transmembrane transporter activity GO:0022898 22 19 0,000 0,02210497 0,03393894 GO:0032409|regulation of transporter activity, ! regulation of survival gene product expression GO:0045884 23 19 0,000 0,02210497 0,03392467 ! activation of pro-apoptotic gene products GO:0008633 26 19 0,000 0,02210497 0,0339104 ! deoxyribonucleotide metabolic process GO:0009262 20 19 0,000 0,02210497 0,03389615 ! lysosome organization GO:0007040 20 19 0,000 0,02210497 0,0338819 ! cellular macromolecular complex disassembly GO:0034623 23 19 0,000 0,02210497 0,03386767 ! central nervous system neuron development GO:0021954 21 19 0,000 0,02210497 0,03385345 ! threonine-type endopeptidase activity GO:0004298 20 19 0,000 0,02210497 0,03383925 GO:0070003|threonine-type peptidase activity, ! chromosome condensation GO:0030261 20 19 0,000 0,02210497 0,03382505 ! peptidyl-serine phosphorylation GO:0018105 26 19 0,000 0,02210497 0,03381087 ! regulation of endothelial cell migration GO:0010594 22 19 0,000 0,02210497 0,0337967 ! fatty acid beta-oxidation GO:0006635 21 19 0,000 0,02210497 0,03378254 ! peptide cross-linking GO:0018149 23 19 0,000 0,02210497 0,0337684 ! ventricular cardiac muscle morphogenesis GO:0055010 21 19 0,000 0,02210497 0,03375426 ! beta-catenin binding GO:0008013 23 19 0,000 0,02210497 0,03374014 ! positive regulation of locomotion GO:0040017 21 19 0,000 0,02210497 0,03372603 GO:0050921|positive regulation of chemotaxis, ! cell projection membrane GO:0031253 21 19 0,000 0,02210497 0,03371193 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,02210497 0,03369784 ! trans-Golgi network transport vesicle GO:0030140 26 19 0,000 0,02210497 0,03368376 ! sphingolipid biosynthetic process GO:0030148 20 19 0,000 0,02210497 0,0336697 ! vitamin transport GO:0051180 21 19 0,000 0,02210497 0,03365565 ! positive regulation of osteoblast differentiation GO:0045669 22 19 0,000 0,02210497 0,03364161 ! terpenoid metabolic process GO:0006721 20 19 0,000 0,02210497 0,03362758 ! leukotriene biosynthetic process GO:0019370 20 19 0,000 0,02210497 0,03361356 GO:0043450|alkene biosynthetic process, ! nerve development GO:0021675 24 19 0,000 0,02210497 0,03359955 ! retinoid binding GO:0005501 19 19 0,000 0,02210497 0,03358556 GO:0019840|isoprenoid binding, ! regulation of amine transport GO:0051952 23 19 0,000 0,02210497 0,03357158 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 22 19 0,000 0,02210497 0,03355761 ! histone deacetylase activity GO:0004407 20 19 0,000 0,02210497 0,03354365 GO:0033558|protein deacetylase activity, ! regulation of microtubule polymerization or depolymerization GO:0031110 21 19 0,000 0,02210497 0,0335297 ! gluconeogenesis GO:0006094 23 19 0,000 0,02210497 0,03351576 ! post-Golgi vesicle-mediated transport GO:0006892 23 19 0,000 0,02210497 0,03350184 ! microtubule-based transport GO:0010970 20 19 0,000 0,02210497 0,03348793 ! superoxide metabolic process GO:0006801 21 19 0,000 0,02210497 0,03347403 ! C21-steroid hormone metabolic process GO:0008207 20 19 0,000 0,02210497 0,03346014 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,02210497 0,03344626 GO:0006479|protein amino acid methylation, ! L-ascorbic acid binding GO:0031418 19 19 0,000 0,02210497 0,03343239 ! regulation of DNA recombination GO:0000018 38 19 0,000 0,02210497 0,03341854 ! photoreceptor cell maintenance GO:0045494 23 19 0,000 0,02210497 0,03340469 ! positive regulation of cytoskeleton organization GO:0051495 22 19 0,000 0,02210497 0,03339086 ! acetylcholine binding GO:0042166 20 19 0,000 0,02210497 0,03337704 ! heme metabolic process GO:0042168 20 19 0,000 0,02210497 0,03336323 ! SH2 domain binding GO:0042169 25 19 0,000 0,02210497 0,03334943 ! neurotransmitter:sodium symporter activity GO:0005328 21 19 0,000 0,02210497 0,03333565 ! carbohydrate kinase activity GO:0019200 20 19 0,000 0,02210497 0,03332187 ! RNA methyltransferase activity GO:0008173 19 19 0,000 0,02210497 0,03330811 ! RNA-dependent ATPase activity GO:0008186 29 19 0,000 0,02210497 0,03329436 ! body fluid secretion GO:0007589 21 19 0,000 0,02210497 0,03328061 ! neuropeptide hormone activity GO:0005184 25 19 0,000 0,02210497 0,03326689 ! secretory granule membrane GO:0030667 21 19 0,000 0,02210497 0,03325317 ! extracellular-glutamate-gated ion channel activity GO:0005234 23 19 0,000 0,02210497 0,03323946 ! ribonucleoprotein binding GO:0043021 20 19 0,000 0,02210497 0,03322576 ! peptidase activator activity GO:0016504 21 19 0,000 0,02210497 0,03321208 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,02210497 0,03319841 ! small conjugating protein-specific protease activity GO:0019783 21 19 0,000 0,02210497 0,03318474 ! regulation of BMP signaling pathway GO:0030510 20 19 0,000 0,02210497 0,03317109 ! sialyltransferase activity GO:0008373 31 19 0,000 0,02210497 0,03315745 ! ATP-dependent DNA helicase activity GO:0004003 30 19 0,000 0,02210497 0,03314383 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 23 20 0,000 0,02325537 0,0348544 ! regulation of anti-apoptosis GO:0045767 20 20 0,000 0,02325537 0,03484008 ! reciprocal meiotic recombination GO:0007131 40 20 0,000 0,02325537 0,03482578 ! protein amino acid ADP-ribosylation GO:0006471 23 20 0,000 0,02325537 0,03481149 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 30 20 0,000 0,02325537 0,03479721 ! retina development in camera-type eye GO:0060041 24 20 0,000 0,02325537 0,03478294 ! ovarian follicle development GO:0001541 21 20 0,000 0,02325537 0,03476869 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 21 20 0,000 0,02325537 0,03475445 ! hydrogen peroxide metabolic process GO:0042743 20 20 0,000 0,02325537 0,03474021 ! diencephalon development GO:0021536 22 20 0,000 0,02325537 0,03472599 ! nuclear inner membrane GO:0005637 21 20 0,000 0,02325537 0,03471178 ! regulation of lipid transport GO:0032368 22 20 0,000 0,02325537 0,03469759 ! response to glucocorticoid stimulus GO:0051384 22 20 0,000 0,02325537 0,0346834 ! glutathione metabolic process GO:0006749 21 20 0,000 0,02325537 0,03466923 ! transcriptional repressor complex GO:0017053 23 20 0,000 0,02325537 0,03465507 ! vitamin A metabolic process GO:0006776 20 20 0,000 0,02325537 0,03464091 ! positive regulation of lymphocyte differentiation GO:0045621 30 20 0,000 0,02325537 0,03462678 ! negative regulation of cytokine production GO:0001818 23 20 0,000 0,02325537 0,03461265 ! phosphorus-oxygen lyase activity GO:0016849 21 20 0,000 0,02325537 0,03459853 ! peptide hormone secretion GO:0030072 25 20 0,000 0,02325537 0,03458443 GO:0002790|peptide secretion, ! actin filament-based movement GO:0030048 22 20 0,000 0,02325537 0,03457033 ! Rab GTPase binding GO:0017137 22 20 0,000 0,02325537 0,03455625 ! initiation of viral infection GO:0019059 22 20 0,000 0,02325537 0,03454218 ! voltage-gated anion channel activity GO:0008308 23 20 0,000 0,02325537 0,03452812 ! heterochromatin GO:0000792 20 20 0,000 0,02325537 0,03451408 ! aminoglycan catabolic process GO:0006026 22 20 0,000 0,02325537 0,03450004 ! glycosaminoglycan biosynthetic process GO:0006024 21 20 0,000 0,02325537 0,03448602 ! regulation of chemotaxis GO:0050920 22 20 0,000 0,02325537 0,034472 ! calcium-independent cell-cell adhesion GO:0016338 27 20 0,000 0,02325537 0,034458 ! high-density lipoprotein particle GO:0034364 30 20 0,000 0,02325537 0,03444401 ! visual behavior GO:0007632 34 20 0,000 0,02325537 0,03443003 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 23 20 0,000 0,02325537 0,03441607 ! immune response-activating cell surface receptor signaling pathway GO:0002429 27 20 0,000 0,02325537 0,03440211 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! vesicle docking during exocytosis GO:0006904 21 20 0,000 0,02325537 0,03438816 ! cell structure disassembly during apoptosis GO:0006921 31 20 0,000 0,02325537 0,03437423 ! nucleotide kinase activity GO:0019201 26 20 0,000 0,02325537 0,03436031 ! rRNA binding GO:0019843 22 20 0,000 0,02325537 0,0343464 ! cytolysis GO:0019835 22 20 0,000 0,02325537 0,0343325 ! renal system process GO:0003014 22 20 0,000 0,02325537 0,03431861 ! specific transcriptional repressor activity GO:0016566 23 20 0,000 0,02325537 0,03430473 ! fatty acid transport GO:0015908 23 20 0,000 0,02325537 0,03429087 ! transaminase activity GO:0008483 22 20 0,000 0,02325537 0,03427701 ! activation of JUN kinase activity GO:0007257 22 20 0,000 0,02325537 0,03426317 ! collagen catabolic process GO:0030574 21 20 0,000 0,02325537 0,03424933 ! microvillus GO:0005902 25 20 0,000 0,02325537 0,03423551 ! tumor necrosis factor receptor binding GO:0005164 22 20 0,000 0,02325537 0,0342217 ! connexon complex GO:0005922 23 20 0,000 0,02325537 0,0342079 ! positive regulation of DNA replication GO:0045740 27 21 0,000 0,02440448 0,03588374 ! positive regulation of protein catabolic process GO:0045732 23 21 0,000 0,02440448 0,03586928 ! translational initiation GO:0006413 21 21 0,000 0,02440448 0,03585484 ! NF-kappaB binding GO:0051059 31 21 0,000 0,02440448 0,0358404 ! heterotrimeric G-protein complex GO:0005834 23 21 0,000 0,02440448 0,03582598 ! positive regulation of bone remodeling GO:0046852 22 21 0,000 0,02440448 0,03581157 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 21 0,000 0,02440448 0,03579717 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! transition metal ion transmembrane transporter activity GO:0046915 25 21 0,000 0,02440448 0,03578278 ! glutathione transferase activity GO:0004364 21 21 0,000 0,02440448 0,0357684 ! voltage-gated calcium channel complex GO:0005891 28 21 0,000 0,02440448 0,03575404 ! glutamate signaling pathway GO:0007215 23 21 0,000 0,02440448 0,03573969 ! regeneration GO:0031099 24 21 0,000 0,02440448 0,03572534 ! apoptotic mitochondrial changes GO:0008637 33 21 0,000 0,02440448 0,03571101 ! MHC class I protein complex GO:0042612 31 21 0,000 0,02440448 0,0356967 ! cellular response to starvation GO:0009267 22 21 0,000 0,02440448 0,03568239 ! peroxisome organization GO:0007031 22 21 0,000 0,02440448 0,03566809 ! vacuole organization GO:0007033 23 21 0,000 0,02440448 0,03565381 ! apoptotic nuclear changes GO:0030262 24 21 0,000 0,02440448 0,03563954 ! response to lipopolysaccharide GO:0032496 31 21 0,000 0,02440448 0,03562527 ! neural crest cell development GO:0014032 24 21 0,000 0,02440448 0,03561102 GO:0014033|neural crest cell differentiation, ! regulation of protein binding GO:0043393 25 21 0,000 0,02440448 0,03559678 ! nucleobase metabolic process GO:0009112 23 21 0,000 0,02440448 0,03558256 ! regulation of steroid metabolic process GO:0019218 23 21 0,000 0,02440448 0,03556834 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,02440448 0,03555414 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! monocarboxylic acid transmembrane transporter activity GO:0008028 25 21 0,000 0,02440448 0,03553994 ! pallium development GO:0021543 22 21 0,000 0,02440448 0,03552576 ! synaptic vesicle transport GO:0048489 25 21 0,000 0,02440448 0,03551159 ! negative regulation of Wnt receptor signaling pathway GO:0030178 22 21 0,000 0,02440448 0,03549743 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 21 0,000 0,02440448 0,03548328 ! leukocyte homeostasis GO:0001776 22 21 0,000 0,02440448 0,03546915 ! negative regulation of neuron differentiation GO:0045665 22 21 0,000 0,02440448 0,03545502 ! cyclase activity GO:0009975 22 21 0,000 0,02440448 0,03544091 ! aspartate family amino acid metabolic process GO:0009066 24 21 0,000 0,02440448 0,0354268 ! gut development GO:0048565 23 21 0,000 0,02440448 0,03541271 ! calcium-dependent phospholipid binding GO:0005544 22 21 0,000 0,02440448 0,03539863 ! negative regulation of T cell activation GO:0050868 23 21 0,000 0,02440448 0,03538456 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,02440448 0,0353705 ! cortical actin cytoskeleton GO:0030864 21 21 0,000 0,02440448 0,03535646 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,02440448 0,03534242 ! membrane lipid biosynthetic process GO:0046467 22 21 0,000 0,02440448 0,0353284 ! nucleotide-excision repair, DNA damage removal GO:0000718 22 21 0,000 0,02440448 0,03531438 ! axis specification GO:0009798 25 21 0,000 0,02440448 0,03530038 ! response to alkaloid GO:0043279 27 21 0,000 0,02440448 0,03528639 ! 4 iron, 4 sulfur cluster binding GO:0051539 24 21 0,000 0,02440448 0,03527241 ! response to ethanol GO:0045471 28 21 0,000 0,02440448 0,03525844 ! response to carbohydrate stimulus GO:0009743 24 21 0,000 0,02440448 0,03524448 ! smooth muscle contraction GO:0006939 25 21 0,000 0,02440448 0,03523053 ! ubiquitin binding GO:0043130 25 21 0,000 0,02440448 0,0352166 ! vesicle targeting GO:0006903 22 21 0,000 0,02440448 0,03520267 ! phospholipase A2 activity GO:0004623 32 21 0,000 0,02440448 0,03518876 ! SNARE binding GO:0000149 24 21 0,000 0,02440448 0,03517486 ! interaction with host GO:0051701 26 21 0,000 0,02440448 0,03516096 ! positive regulation of myeloid leukocyte differentiation GO:0002763 26 21 0,000 0,02440448 0,03514708 ! lymphocyte proliferation GO:0046651 24 21 0,000 0,02440448 0,03513321 ! regulation of tumor necrosis factor production GO:0032680 24 21 0,000 0,02440448 0,03511935 ! regulation of interleukin-2 production GO:0032663 21 21 0,000 0,02440448 0,0351055 ! negative regulation of angiogenesis GO:0016525 23 21 0,000 0,02440448 0,03509167 ! cell-cell junction organization GO:0045216 24 21 0,000 0,02440448 0,03507784 ! single-stranded RNA binding GO:0003727 22 21 0,000 0,02440448 0,03506402 ! cyclic nucleotide binding GO:0030551 25 21 0,000 0,02440448 0,03505022 ! caveola GO:0005901 25 21 0,000 0,02440448 0,03503643 ! water-soluble vitamin biosynthetic process GO:0042364 23 21 0,000 0,02440448 0,03502264 ! insulin receptor binding GO:0005158 25 21 0,000 0,02440448 0,03500887 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,02440448 0,03499511 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,02440448 0,03498136 ! mRNA export from nucleus GO:0006406 26 22 0,000 0,02555231 0,03661226 ! metencephalon development GO:0022037 25 22 0,000 0,02555231 0,03659788 ! regulation of interferon-gamma production GO:0032649 25 22 0,000 0,02555231 0,03658352 ! hormone secretion GO:0046879 28 22 0,000 0,02555231 0,03656917 ! vesicle docking GO:0048278 24 22 0,000 0,02555231 0,03655483 ! muscle myosin complex GO:0005859 23 22 0,000 0,02555231 0,0365405 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 24 22 0,000 0,02555231 0,03652618 ! actomyosin structure organization GO:0031032 24 22 0,000 0,02555231 0,03651187 ! positive regulation of innate immune response GO:0045089 23 22 0,000 0,02555231 0,03649758 ! sperm motility GO:0030317 23 22 0,000 0,02555231 0,03648329 ! potassium channel regulator activity GO:0015459 29 22 0,000 0,02555231 0,03646902 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 24 22 0,000 0,02555231 0,03645476 ! vacuolar transport GO:0007034 22 22 0,000 0,02555231 0,0364405 ! oxidoreductase activity, acting on heme group of donors GO:0016675 23 22 0,000 0,02555231 0,03642626 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! central nervous system neuron differentiation GO:0021953 24 22 0,000 0,02555231 0,03641203 ! cellular response to reactive oxygen species GO:0034614 26 22 0,000 0,02555231 0,03639782 ! purine ribonucleoside metabolic process GO:0046128 24 22 0,000 0,02555231 0,03638361 GO:0042278|purine nucleoside metabolic process, ! G-protein chemoattractant receptor activity GO:0001637 24 22 0,000 0,02555231 0,03636941 GO:0004950|chemokine receptor activity, ! response to corticosteroid stimulus GO:0031960 25 22 0,000 0,02555231 0,03635523 ! PML body GO:0016605 25 22 0,000 0,02555231 0,03634106 ! barbed-end actin filament capping GO:0051016 24 22 0,000 0,02555231 0,03632689 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 27 22 0,000 0,02555231 0,03631274 ! regulation of foam cell differentiation GO:0010743 28 22 0,000 0,02555231 0,0362986 ! cyclic nucleotide biosynthetic process GO:0009190 23 22 0,000 0,02555231 0,03628447 ! leukotriene metabolic process GO:0006691 23 22 0,000 0,02555231 0,03627035 ! glycosphingolipid metabolic process GO:0006687 23 22 0,000 0,02555231 0,03625625 ! deacetylase activity GO:0019213 23 22 0,000 0,02555231 0,03624215 ! pentose metabolic process GO:0019321 23 22 0,000 0,02555231 0,03622806 ! collagen fibril organization GO:0030199 32 22 0,000 0,02555231 0,03621399 ! regulation of response to biotic stimulus GO:0002831 33 22 0,000 0,02555231 0,03619993 ! positive regulation of adaptive immune response GO:0002821 22 22 0,000 0,02555231 0,03618587 ! peptidyl-serine modification GO:0018209 30 22 0,000 0,02555231 0,03617183 ! DNA-directed RNA polymerase complex GO:0000428 23 22 0,000 0,02555231 0,0361578 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 32 22 0,000 0,02555231 0,03614378 ! positive regulation of behavior GO:0048520 24 22 0,000 0,02555231 0,03612977 ! regulation of generation of precursor metabolites and energy GO:0043467 25 22 0,000 0,02555231 0,03611577 ! aromatic compound catabolic process GO:0019439 23 22 0,000 0,02555231 0,03610178 ! embryonic epithelial tube formation GO:0001838 25 22 0,000 0,02555231 0,03608781 GO:0001841|neural tube formation, ! telomere organization GO:0032200 43 22 0,000 0,02555231 0,03607384 GO:0000723|telomere maintenance, ! acetyl-CoA catabolic process GO:0046356 24 22 0,000 0,02555231 0,03605989 GO:0006099|tricarboxylic acid cycle, ! protein tetramerization GO:0051262 25 22 0,000 0,02555231 0,03604594 ! DNA catabolic process, endonucleolytic GO:0000737 24 22 0,000 0,02555231 0,03603201 ! glycerol metabolic process GO:0006071 24 22 0,000 0,02555231 0,03601809 ! cellular component assembly involved in morphogenesis GO:0010927 23 22 0,000 0,02555231 0,03600417 ! nuclear chromatin GO:0000790 23 22 0,000 0,02555231 0,03599027 ! cellular iron ion homeostasis GO:0006879 25 22 0,000 0,02555231 0,03597638 ! aminoglycan biosynthetic process GO:0006023 23 22 0,000 0,02555231 0,0359625 ! positive regulation of JAK-STAT cascade GO:0046427 25 22 0,000 0,02555231 0,03594863 ! sterol binding GO:0032934 24 22 0,000 0,02555231 0,03593478 ! calcium-dependent cell-cell adhesion GO:0016339 23 22 0,000 0,02555231 0,03592093 ! digestive system process GO:0022600 25 22 0,000 0,02555231 0,03590709 ! neurotransmitter transporter activity GO:0005326 24 22 0,000 0,02555231 0,03589326 ! organic acid:sodium symporter activity GO:0005343 25 22 0,000 0,02555231 0,03587945 ! nonmotile primary cilium GO:0031513 24 22 0,000 0,02555231 0,03586564 ! negative regulation of myeloid leukocyte differentiation GO:0002762 26 22 0,000 0,02555231 0,03585185 ! base-excision repair GO:0006284 33 22 0,000 0,02555231 0,03583807 ! regulation of chromosome organization GO:0033044 27 22 0,000 0,02555231 0,03582429 ! DNA modification GO:0006304 25 22 0,000 0,02555231 0,03581053 ! detection of chemical stimulus GO:0009593 23 22 0,000 0,02555231 0,03579678 ! positive regulation of tissue remodeling GO:0034105 23 22 0,000 0,02555231 0,03578304 ! GABA-A receptor activity GO:0004890 27 22 0,000 0,02555231 0,0357693 ! response to cytokine stimulus GO:0034097 25 22 0,000 0,02555231 0,03575558 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 24 22 0,000 0,02555231 0,03574187 ! pyrimidine nucleoside metabolic process GO:0006213 27 22 0,000 0,02555231 0,03572818 ! phosphoprotein phosphatase inhibitor activity GO:0004864 25 22 0,000 0,02555231 0,03571449 ! solute:cation antiporter activity GO:0015298 23 22 0,000 0,02555231 0,03570081 ! regulation of transmembrane transport GO:0034762 28 23 0,000 0,02669884 0,03728842 ! protein amino acid O-linked glycosylation GO:0006493 28 23 0,000 0,02669884 0,03727415 ! leukocyte adhesion GO:0007159 26 23 0,000 0,02669884 0,03725989 ! dicarboxylic acid metabolic process GO:0043648 27 23 0,000 0,02669884 0,03724564 ! odontogenesis of dentine-containing tooth GO:0042475 26 23 0,000 0,02669884 0,03723141 ! positive regulation of endocytosis GO:0045807 25 23 0,000 0,02669884 0,03721718 ! mitochondrial membrane organization GO:0007006 25 23 0,000 0,02669884 0,03720296 ! ureteric bud development GO:0001657 24 23 0,000 0,02669884 0,03718876 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 27 23 0,000 0,02669884 0,03717456 ! regulation of insulin secretion GO:0050796 27 23 0,000 0,02669884 0,03716038 ! vitamin biosynthetic process GO:0009110 25 23 0,000 0,02669884 0,03714621 ! negative regulation of neurogenesis GO:0050768 29 23 0,000 0,02669884 0,03713205 ! cholesterol biosynthetic process GO:0006695 29 23 0,000 0,02669884 0,03711789 ! deaminase activity GO:0019239 24 23 0,000 0,02669884 0,03710375 ! sensory perception of pain GO:0019233 26 23 0,000 0,02669884 0,03708963 ! lipid kinase activity GO:0001727 26 23 0,000 0,02669884 0,03707551 ! platelet activation GO:0030168 27 23 0,000 0,02669884 0,0370614 ! proteoglycan biosynthetic process GO:0030166 24 23 0,000 0,02669884 0,0370473 ! positive regulation of intracellular transport GO:0032388 26 23 0,000 0,02669884 0,03703322 ! regulation of blood coagulation GO:0030193 26 23 0,000 0,02669884 0,03701914 ! regulation of cytokine secretion GO:0050707 27 23 0,000 0,02669884 0,03700507 ! fat-soluble vitamin metabolic process GO:0006775 23 23 0,000 0,02669884 0,03699102 ! cellular alkene metabolic process GO:0043449 24 23 0,000 0,02669884 0,03697698 ! aromatic amino acid family metabolic process GO:0009072 25 23 0,000 0,02669884 0,03696294 ! cell surface binding GO:0043498 28 23 0,000 0,02669884 0,03694892 ! porphyrin metabolic process GO:0006778 24 23 0,000 0,02669884 0,03693491 GO:0033013|tetrapyrrole metabolic process, ! ligase activity, forming carbon-sulfur bonds GO:0016877 24 23 0,000 0,02669884 0,03692091 ! regulation of glucose import GO:0046324 28 23 0,000 0,02669884 0,03690692 ! insulin-like growth factor binding GO:0005520 27 23 0,000 0,02669884 0,03689294 ! alditol metabolic process GO:0019400 25 23 0,000 0,02669884 0,03687897 ! positive regulation of JUN kinase activity GO:0043507 25 23 0,000 0,02669884 0,03686501 ! pyruvate metabolic process GO:0006090 27 23 0,000 0,02669884 0,03685106 ! zinc ion transport GO:0006829 26 23 0,000 0,02669884 0,03683712 ! N-acetylglucosamine metabolic process GO:0006044 26 23 0,000 0,02669884 0,0368232 ! antigen processing and presentation of peptide antigen GO:0048002 30 23 0,000 0,02669884 0,03680928 ! sex determination GO:0007530 25 23 0,000 0,02669884 0,03679537 ! phosphate binding GO:0042301 25 23 0,000 0,02669884 0,03678148 ! positive regulation of leukocyte mediated immunity GO:0002705 24 23 0,000 0,02669884 0,03676759 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of interleukin-6 production GO:0032675 26 23 0,000 0,02669884 0,03675372 ! nuclear-transcribed mRNA catabolic process GO:0000956 26 23 0,000 0,02669884 0,03673986 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 28 23 0,000 0,02669884 0,036726 ! ubiquitin protein ligase binding GO:0031625 24 23 0,000 0,02669884 0,03671216 ! synaptogenesis GO:0007416 25 23 0,000 0,02669884 0,03669833 ! regulation of bone mineralization GO:0030500 23 23 0,000 0,02669884 0,0366845 ! neurotransmitter secretion GO:0007269 26 23 0,000 0,02669884 0,03667069 ! ethanolamine and derivative metabolic process GO:0042439 34 23 0,000 0,02669884 0,03665689 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 25 23 0,000 0,02669884 0,0366431 ! leukocyte proliferation GO:0070661 26 23 0,000 0,02669884 0,03662932 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 24 23 0,000 0,02669884 0,03661555 ! oligosaccharide metabolic process GO:0009311 29 24 0,000 0,02784408 0,03817182 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,02784408 0,03815748 ! pancreas development GO:0031016 27 24 0,000 0,02784408 0,03814315 ! calcium channel complex GO:0034704 31 24 0,000 0,02784408 0,03812883 ! coenzyme catabolic process GO:0009109 26 24 0,000 0,02784408 0,03811452 ! negative regulation of cell development GO:0010721 30 24 0,000 0,02784408 0,03810023 ! cardiac muscle tissue morphogenesis GO:0055008 27 24 0,000 0,02784408 0,03808594 GO:0060415|muscle tissue morphogenesis, ! phosphatase inhibitor activity GO:0019212 27 24 0,000 0,02784408 0,03807167 ! regulation of ARF GTPase activity GO:0032312 28 24 0,000 0,02784408 0,0380574 ! regulation of oxidoreductase activity GO:0051341 24 24 0,000 0,02784408 0,03804315 ! RNA splicing factor activity, transesterification mechanism GO:0031202 25 24 0,000 0,02784408 0,03802891 ! Rho GTPase binding GO:0017048 36 24 0,000 0,02784408 0,03801467 ! regulation of glucose transport GO:0010827 29 24 0,000 0,02784408 0,03800045 ! serine family amino acid metabolic process GO:0009069 27 24 0,000 0,02784408 0,03798624 ! intramolecular transferase activity GO:0016866 26 24 0,000 0,02784408 0,03797204 ! phosphoinositide phospholipase C activity GO:0004435 28 24 0,000 0,02784408 0,03795785 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! Z disc GO:0030018 27 24 0,000 0,02784408 0,03794367 ! protein stabilization GO:0050821 24 24 0,000 0,02784408 0,0379295 ! protein import into nucleus, translocation GO:0000060 27 24 0,000 0,02784408 0,03791534 ! embryonic pattern specification GO:0009880 29 24 0,000 0,02784408 0,0379012 ! negative regulation of actin filament depolymerization GO:0030835 26 24 0,000 0,02784408 0,03788706 ! RNA polymerase complex GO:0030880 25 24 0,000 0,02784408 0,03787293 ! cellular polysaccharide biosynthetic process GO:0033692 24 24 0,000 0,02784408 0,03785882 ! glucosamine metabolic process GO:0006041 27 24 0,000 0,02784408 0,03784471 ! small conjugating protein binding GO:0032182 29 24 0,000 0,02784408 0,03783062 ! regulation of transcription factor import into nucleus GO:0042990 26 24 0,000 0,02784408 0,03781653 ! chemokine binding GO:0019956 26 24 0,000 0,02784408 0,03780246 ! catechol metabolic process GO:0009712 29 24 0,000 0,02784408 0,0377884 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of smooth muscle contraction GO:0006940 28 24 0,000 0,02784408 0,03777434 ! NAD+ ADP-ribosyltransferase activity GO:0003950 26 24 0,000 0,02784408 0,0377603 ! multicellular organismal response to stress GO:0033555 27 24 0,000 0,02784408 0,03774627 ! cell aging GO:0007569 47 24 0,000 0,02784408 0,03773225 ! immune response-activating signal transduction GO:0002757 31 24 0,000 0,02784408 0,03771823 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 24 0,000 0,02784408 0,03770423 ! fibroblast growth factor receptor signaling pathway GO:0008543 27 24 0,000 0,02784408 0,03769024 ! voltage-gated calcium channel activity GO:0005245 31 24 0,000 0,02784408 0,03767626 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 29 24 0,000 0,02784408 0,03766229 ! metallocarboxypeptidase activity GO:0004181 24 24 0,000 0,02784408 0,03764833 ! 3'-5' exonuclease activity GO:0008408 43 24 0,000 0,02784408 0,03763439 ! small nuclear ribonucleoprotein complex GO:0030532 24 24 0,000 0,02784408 0,03762045 ! selenium binding GO:0008430 24 24 0,000 0,02784408 0,03760652 ! spindle pole GO:0000922 35 24 0,000 0,02784408 0,0375926 ! Rho GTPase activator activity GO:0005100 28 24 0,000 0,02784408 0,03757869 ! phenol metabolic process GO:0018958 31 25 0,000 0,02898804 0,03910812 ! protein amino acid acylation GO:0043543 28 25 0,000 0,02898804 0,03909366 ! aromatase activity GO:0070330 28 25 0,000 0,02898804 0,03907922 ! cholesterol homeostasis GO:0042632 27 25 0,000 0,02898804 0,03906478 GO:0055092|sterol homeostasis, ! positive regulation of epithelial cell proliferation GO:0050679 29 25 0,000 0,02898804 0,03905036 ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 29 25 0,000 0,02898804 0,03903594 ! response to starvation GO:0042594 26 25 0,000 0,02898804 0,03902154 ! dynein complex GO:0030286 28 25 0,000 0,02898804 0,03900714 ! ARF GTPase activator activity GO:0008060 29 25 0,000 0,02898804 0,03899276 ! regulation of behavior GO:0050795 27 25 0,000 0,02898804 0,03897839 ! regulation of biomineral formation GO:0070167 25 25 0,000 0,02898804 0,03896402 ! hexose biosynthetic process GO:0019319 31 25 0,000 0,02898804 0,03894967 ! group transfer coenzyme metabolic process GO:0006752 25 25 0,000 0,02898804 0,03893533 ! hormone transport GO:0009914 31 25 0,000 0,02898804 0,038921 ! response to molecule of bacterial origin GO:0002237 35 25 0,000 0,02898804 0,03890668 ! cell adhesion molecule binding GO:0050839 29 25 0,000 0,02898804 0,03889237 ! regulation of coagulation GO:0050818 28 25 0,000 0,02898804 0,03887807 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,02898804 0,03886379 ! myeloid leukocyte differentiation GO:0002573 28 25 0,000 0,02898804 0,03884951 ! acetyl-CoA metabolic process GO:0006084 27 25 0,000 0,02898804 0,03883524 ! chromosome, telomeric region GO:0000781 38 25 0,000 0,02898804 0,03882099 ! molting cycle process GO:0022404 28 25 0,000 0,02898804 0,03880674 GO:0022405|hair cycle process, GO:0001942|hair follicle development, ! collagen metabolic process GO:0032963 26 25 0,000 0,02898804 0,0387925 ! xenobiotic metabolic process GO:0006805 27 25 0,000 0,02898804 0,03877828 ! phototransduction GO:0007602 27 25 0,000 0,02898804 0,03876406 ! negative regulation of response to external stimulus GO:0032102 30 25 0,000 0,02898804 0,03874986 ! regulation of endothelial cell proliferation GO:0001936 29 25 0,000 0,02898804 0,03873566 ! protein phosphatase binding GO:0019903 27 25 0,000 0,02898804 0,03872148 ! negative regulation of DNA replication GO:0008156 31 25 0,000 0,02898804 0,03870731 ! multicellular organismal catabolic process GO:0044243 27 25 0,000 0,02898804 0,03869314 ! autophagy GO:0006914 28 25 0,000 0,02898804 0,03867899 ! steroid dehydrogenase activity GO:0016229 27 25 0,000 0,02898804 0,03866485 ! response to ionizing radiation GO:0010212 37 25 0,000 0,02898804 0,03865072 ! DNA-directed DNA polymerase activity GO:0003887 30 25 0,000 0,02898804 0,0386366 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 31 26 0,000 0,03013071 0,04014494 ! epidermal growth factor receptor signaling pathway GO:0007173 32 26 0,000 0,03013071 0,04013028 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 29 26 0,000 0,03013071 0,04011563 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 26 0,000 0,03013071 0,040101 ! positive regulation of lipid metabolic process GO:0045834 27 26 0,000 0,03013071 0,04008637 ! hair cycle GO:0042633 29 26 0,000 0,03013071 0,04007176 GO:0042303|molting cycle, ! thyroid hormone receptor binding GO:0046966 30 26 0,000 0,03013071 0,04005715 ! polysaccharide catabolic process GO:0000272 39 26 0,000 0,03013071 0,04004256 ! peptidyl-tyrosine phosphorylation GO:0018108 30 26 0,000 0,03013071 0,04002798 ! early endosome membrane GO:0031901 31 26 0,000 0,03013071 0,04001341 ! negative regulation of protein kinase cascade GO:0010741 40 26 0,000 0,03013071 0,03999885 ! iron ion homeostasis GO:0055072 29 26 0,000 0,03013071 0,0399843 ! glycolipid metabolic process GO:0006664 36 26 0,000 0,03013071 0,03996976 ! GABA receptor activity GO:0016917 31 26 0,000 0,03013071 0,03995523 ! PDZ domain binding GO:0030165 28 26 0,000 0,03013071 0,03994071 ! positive regulation of protein secretion GO:0050714 29 26 0,000 0,03013071 0,0399262 ! regulation of cellular carbohydrate metabolic process GO:0010675 29 26 0,000 0,03013071 0,0399117 ! AP-type membrane coat adaptor complex GO:0030119 30 26 0,000 0,03013071 0,03989722 GO:0030131|clathrin adaptor complex, ! neuromuscular process controlling balance GO:0050885 32 26 0,000 0,03013071 0,03988274 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 45 26 0,000 0,03013071 0,03986827 ! fatty acid binding GO:0005504 28 26 0,000 0,03013071 0,03985382 ! blastocyst development GO:0001824 27 26 0,000 0,03013071 0,03983937 ! regulation of JUN kinase activity GO:0043506 28 26 0,000 0,03013071 0,03982494 ! lysine N-acetyltransferase activity GO:0004468 29 26 0,000 0,03013071 0,03981052 GO:0004402|histone acetyltransferase activity, ! negative regulation of protein polymerization GO:0032272 37 26 0,000 0,03013071 0,0397961 ! regulation of smooth muscle cell proliferation GO:0048660 30 26 0,000 0,03013071 0,0397817 ! regulation of actin filament depolymerization GO:0030834 28 26 0,000 0,03013071 0,03976731 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,03013071 0,03975292 ! iron ion transport GO:0006826 33 26 0,000 0,03013071 0,03973855 ! regulation of synaptic plasticity GO:0048167 36 26 0,000 0,03013071 0,03972419 ! glucose transport GO:0015758 27 26 0,000 0,03013071 0,03970984 ! insulin receptor signaling pathway GO:0008286 34 26 0,000 0,03013071 0,0396955 ! spinal cord development GO:0021510 30 26 0,000 0,03013071 0,03968117 ! histone deacetylase complex GO:0000118 29 26 0,000 0,03013071 0,03966685 ! regulation of peptide secretion GO:0002791 30 26 0,000 0,03013071 0,03965254 ! regulation of production of molecular mediator of immune response GO:0002700 27 26 0,000 0,03013071 0,03963824 ! RNA helicase activity GO:0003724 46 26 0,000 0,03013071 0,03962395 ! brush border GO:0005903 30 26 0,000 0,03013071 0,03960967 ! gap junction GO:0005921 29 26 0,000 0,03013071 0,0395954 ! anion:cation symporter activity GO:0015296 29 26 0,000 0,03013071 0,03958114 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 39 27 0,000 0,0312721 0,04106574 ! mRNA catabolic process GO:0006402 31 27 0,000 0,0312721 0,04105096 ! myelination GO:0042552 31 27 0,000 0,0312721 0,04103619 ! trans-Golgi network GO:0005802 31 27 0,000 0,0312721 0,04102144 ! transferase activity, transferring nitrogenous groups GO:0016769 29 27 0,000 0,0312721 0,04100669 ! spliceosomal snRNP biogenesis GO:0000387 29 27 0,000 0,0312721 0,04099196 ! solute:solute antiporter activity GO:0015300 28 27 0,000 0,0312721 0,04097723 ! vasculogenesis GO:0001570 32 27 0,000 0,0312721 0,04096252 ! hexose transport GO:0008645 28 27 0,000 0,0312721 0,04094782 GO:0015749|monosaccharide transport, ! regulation of innate immune response GO:0045088 28 27 0,000 0,0312721 0,04093313 ! spindle organization GO:0007051 38 27 0,000 0,0312721 0,04091844 ! cellular response to oxidative stress GO:0034599 32 27 0,000 0,0312721 0,04090377 ! response to organic cyclic substance GO:0014070 34 27 0,000 0,0312721 0,04088911 ! cell fate determination GO:0001709 29 27 0,000 0,0312721 0,04087446 ! lipid oxidation GO:0034440 29 27 0,000 0,0312721 0,04085982 GO:0019395|fatty acid oxidation, ! fatty acid catabolic process GO:0009062 31 27 0,000 0,0312721 0,04084519 ! collagen binding GO:0005518 29 27 0,000 0,0312721 0,04083057 ! carboxy-lyase activity GO:0016831 27 27 0,000 0,0312721 0,04081596 ! phospholipid transporter activity GO:0005548 30 27 0,000 0,0312721 0,04080137 ! liver development GO:0001889 33 27 0,000 0,0312721 0,04078678 ! mitotic sister chromatid segregation GO:0000070 46 27 0,000 0,0312721 0,0407722 ! determination of bilateral symmetry GO:0009855 32 27 0,000 0,0312721 0,04075763 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! integrin complex GO:0008305 30 27 0,000 0,0312721 0,04074308 ! membrane docking GO:0022406 29 27 0,000 0,0312721 0,04072853 ! detection of light stimulus involved in sensory perception GO:0050962 29 27 0,000 0,0312721 0,040714 GO:0050908|detection of light stimulus involved in visual perception, ! multicellular organismal macromolecule metabolic process GO:0044259 28 27 0,000 0,0312721 0,04069947 ! respiratory gaseous exchange GO:0007585 30 27 0,000 0,0312721 0,04068496 ! phospholipid transport GO:0015914 29 27 0,000 0,0312721 0,04067045 ! sarcoplasmic reticulum GO:0016529 29 27 0,000 0,0312721 0,04065596 ! aminopeptidase activity GO:0004177 33 27 0,000 0,0312721 0,04064147 ! cellular response to nutrient levels GO:0031669 28 27 0,000 0,0312721 0,040627 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 33 27 0,000 0,0312721 0,04061254 ! biogenic amine biosynthetic process GO:0042401 29 27 0,000 0,0312721 0,04059809 ! negative regulation of transcription regulator activity GO:0090048 32 27 0,000 0,0312721 0,04058364 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 29 27 0,000 0,0312721 0,04056921 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 31 28 0,000 0,03241221 0,04203332 ! Golgi stack GO:0005795 30 28 0,000 0,03241221 0,04201838 ! male gonad development GO:0008584 32 28 0,000 0,03241221 0,04200346 ! lipoprotein binding GO:0008034 31 28 0,000 0,03241221 0,04198854 ! mesoderm formation GO:0001707 34 28 0,000 0,03241221 0,04197363 ! negative regulation of MAP kinase activity GO:0043407 30 28 0,000 0,03241221 0,04195874 ! peptidyl-tyrosine modification GO:0018212 32 28 0,000 0,03241221 0,04194386 ! deoxyribonuclease activity GO:0004536 56 28 0,000 0,03241221 0,04192898 ! nicotinamide metabolic process GO:0006769 32 28 0,000 0,03241221 0,04191412 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 31 28 0,000 0,03241221 0,04189927 ! regulation of osteoblast differentiation GO:0045667 33 28 0,000 0,03241221 0,04188442 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 30 28 0,000 0,03241221 0,04186959 ! negative regulation of neuron apoptosis GO:0043524 39 28 0,000 0,03241221 0,04185477 ! tissue homeostasis GO:0001894 31 28 0,000 0,03241221 0,04183996 GO:0048871|multicellular organismal homeostasis, ! DNA damage checkpoint GO:0000077 48 28 0,000 0,03241221 0,04182516 ! negative regulation of protein complex assembly GO:0031333 39 28 0,000 0,03241221 0,04181037 ! regulation of carbohydrate metabolic process GO:0006109 31 28 0,000 0,03241221 0,04179559 ! sister chromatid segregation GO:0000819 49 28 0,000 0,03241221 0,04178082 ! post-embryonic development GO:0009791 32 28 0,000 0,03241221 0,04176606 ! complement activation, classical pathway GO:0006958 33 28 0,000 0,03241221 0,04175132 ! detection of visible light GO:0009584 30 28 0,000 0,03241221 0,04173658 ! calcium-mediated signaling GO:0019722 30 28 0,000 0,03241221 0,04172185 ! receptor regulator activity GO:0030545 31 28 0,000 0,03241221 0,04170714 ! acetylgalactosaminyltransferase activity GO:0008376 33 28 0,000 0,03241221 0,04169243 ! symbiosis, encompassing mutualism through parasitism GO:0044403 33 28 0,000 0,03241221 0,04167773 ! response to heat GO:0009408 33 28 0,000 0,03241221 0,04166305 ! response to xenobiotic stimulus GO:0009410 31 28 0,000 0,03241221 0,04164837 ! response to hydrogen peroxide GO:0042542 32 29 0,000 0,03355103 0,04309654 ! hormone binding GO:0042562 31 29 0,000 0,03355103 0,04308137 ! establishment or maintenance of cell polarity GO:0007163 34 29 0,000 0,03355103 0,04306621 ! striated muscle cell differentiation GO:0051146 42 29 0,000 0,03355103 0,04305106 ! NADP or NADPH binding GO:0050661 33 29 0,000 0,03355103 0,04303592 ! nucleotide receptor activity, G-protein coupled GO:0001608 31 29 0,000 0,03355103 0,0430208 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 41 29 0,000 0,03355103 0,04300568 ! erythrocyte differentiation GO:0030218 35 29 0,000 0,03355103 0,04299057 ! ceramide metabolic process GO:0006672 29 29 0,000 0,03355103 0,04297548 ! replication fork GO:0005657 42 29 0,000 0,03355103 0,04296039 ! camera-type eye morphogenesis GO:0048593 36 29 0,000 0,03355103 0,04294532 ! monosaccharide biosynthetic process GO:0046364 35 29 0,000 0,03355103 0,04293026 ! negative regulation of lymphocyte activation GO:0051250 32 29 0,000 0,03355103 0,04291521 ! alkaloid metabolic process GO:0009820 33 29 0,000 0,03355103 0,04290016 ! icosanoid biosynthetic process GO:0046456 30 29 0,000 0,03355103 0,04288513 ! regulation of pH GO:0006885 30 29 0,000 0,03355103 0,04287011 ! amino sugar metabolic process GO:0006040 41 29 0,000 0,03355103 0,0428551 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 34 29 0,000 0,03355103 0,0428401 ! phospholipase C activity GO:0004629 43 29 0,000 0,03355103 0,04282511 ! response to mechanical stimulus GO:0009612 33 29 0,000 0,03355103 0,04281013 ! clathrin coated vesicle membrane GO:0030665 33 29 0,000 0,03355103 0,04279516 ! sodium channel activity GO:0005272 33 29 0,000 0,03355103 0,0427802 ! sarcoplasm GO:0016528 31 29 0,000 0,03355103 0,04276526 ! detection of light stimulus GO:0009583 31 29 0,000 0,03355103 0,04275032 ! spermatid development GO:0007286 30 29 0,000 0,03355103 0,04273539 ! DNA polymerase activity GO:0034061 34 29 0,000 0,03355103 0,04272048 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 31 29 0,000 0,03355103 0,04270557 ! sarcolemma GO:0042383 30 29 0,000 0,03355103 0,04269067 ! tumor necrosis factor receptor superfamily binding GO:0032813 31 29 0,000 0,03355103 0,04267579 ! galactosyltransferase activity GO:0008378 33 29 0,000 0,03355103 0,04266091 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,03355103 0,04264605 ! transforming growth factor beta receptor signaling pathway GO:0007179 34 30 0,000 0,03468858 0,04407661 ! mitochondrial nucleoid GO:0042645 44 30 0,000 0,03468858 0,04406126 GO:0009295|nucleoid, ! cholesterol transport GO:0030301 33 30 0,000 0,03468858 0,04404592 GO:0015918|sterol transport, ! histone-lysine N-methyltransferase activity GO:0018024 34 30 0,000 0,03468858 0,0440306 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! cellular carbohydrate biosynthetic process GO:0034637 30 30 0,000 0,03468858 0,04401528 ! scavenger receptor activity GO:0005044 39 30 0,000 0,03468858 0,04399998 ! spliceosome assembly GO:0000245 34 30 0,000 0,03468858 0,04398468 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 39 30 0,000 0,03468858 0,0439694 GO:0004601|peroxidase activity, ! mesoderm morphogenesis GO:0048332 37 30 0,000 0,03468858 0,04395413 ! metanephros development GO:0001656 31 30 0,000 0,03468858 0,04393887 ! glutamate receptor activity GO:0008066 35 30 0,000 0,03468858 0,04392361 ! cyclic nucleotide metabolic process GO:0009187 31 30 0,000 0,03468858 0,04390837 ! positive regulation of MAPKKK cascade GO:0043410 36 30 0,000 0,03468858 0,04389314 ! regulation of macrophage differentiation GO:0045649 37 30 0,000 0,03468858 0,04387792 ! positive regulation of myeloid cell differentiation GO:0045639 37 30 0,000 0,03468858 0,04386272 ! negative regulation of myeloid cell differentiation GO:0045638 35 30 0,000 0,03468858 0,04384752 ! cis-trans isomerase activity GO:0016859 32 30 0,000 0,03468858 0,04383233 ! myeloid leukocyte activation GO:0002274 36 30 0,000 0,03468858 0,04381715 ! negative regulation of protein transport GO:0051224 34 30 0,000 0,03468858 0,04380198 ! condensed nuclear chromosome GO:0000794 31 30 0,000 0,03468858 0,04378683 ! cortical cytoskeleton GO:0030863 33 30 0,000 0,03468858 0,04377168 ! protein-lipid complex GO:0032994 41 30 0,000 0,03468858 0,04375655 GO:0034358|plasma lipoprotein particle, ! circadian rhythm GO:0007623 37 30 0,000 0,03468858 0,04374142 ! phosphatase binding GO:0019902 34 30 0,000 0,03468858 0,04372631 ! acute-phase response GO:0006953 44 30 0,000 0,03468858 0,0437112 ! segmentation GO:0035282 37 30 0,000 0,03468858 0,04369611 ! response to toxin GO:0009636 33 30 0,000 0,03468858 0,04368103 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,03468858 0,04366595 ! antigen binding GO:0003823 33 30 0,000 0,03468858 0,04365089 ! regulation of systemic arterial blood pressure GO:0003073 33 30 0,000 0,03468858 0,04363584 ! Golgi-associated vesicle membrane GO:0030660 37 30 0,000 0,03468858 0,0436208 ! ensheathment of neurons GO:0007272 35 30 0,000 0,03468858 0,04360577 GO:0008366|axon ensheathment, ! JAK-STAT cascade GO:0007259 43 30 0,000 0,03468858 0,04359075 ! vesicle localization GO:0051648 31 30 0,000 0,03468858 0,04357573 ! negative regulation of cell adhesion GO:0007162 34 31 0,000 0,03582485 0,04498762 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,03582485 0,04497214 ! acrosomal vesicle GO:0001669 34 31 0,000 0,03582485 0,04495667 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,03582485 0,04494121 ! protein targeting to membrane GO:0006612 35 31 0,000 0,03582485 0,04492576 ! regulation of axonogenesis GO:0050770 37 31 0,000 0,03582485 0,04491032 ! regulation of T cell differentiation GO:0045580 43 31 0,000 0,03582485 0,0448949 ! formation of primary germ layer GO:0001704 37 31 0,000 0,03582485 0,04487948 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 33 31 0,000 0,03582485 0,04486407 ! endocytic vesicle GO:0030139 33 31 0,000 0,03582485 0,04484868 ! pyridine nucleotide metabolic process GO:0019362 35 31 0,000 0,03582485 0,04483329 ! spermatid differentiation GO:0048515 32 31 0,000 0,03582485 0,04481791 ! neuron fate commitment GO:0048663 44 31 0,000 0,03582485 0,04480255 ! regulation of JAK-STAT cascade GO:0046425 37 31 0,000 0,03582485 0,0447872 ! morphogenesis of embryonic epithelium GO:0016331 36 31 0,000 0,03582485 0,04477185 ! macromolecular complex disassembly GO:0032984 37 31 0,000 0,03582485 0,04475652 ! cell junction assembly GO:0034329 36 31 0,000 0,03582485 0,0447412 ! drug binding GO:0008144 34 31 0,000 0,03582485 0,04472589 ! positive regulation of T cell proliferation GO:0042102 38 31 0,000 0,03582485 0,04471058 ! peptide transport GO:0015833 36 31 0,000 0,03582485 0,04469529 ! DNA integrity checkpoint GO:0031570 51 31 0,000 0,03582485 0,04468001 ! peripheral nervous system development GO:0007422 35 31 0,000 0,03582485 0,04466474 ! I band GO:0031674 34 31 0,000 0,03582485 0,04464948 ! BMP signaling pathway GO:0030509 33 31 0,000 0,03582485 0,04463423 ! adult locomotory behavior GO:0008344 37 31 0,000 0,03582485 0,044619 ! gene silencing GO:0016458 33 31 0,000 0,03582485 0,04460377 ! negative regulation of adenylate cyclase activity GO:0007194 39 32 0,000 0,03695984 0,04600119 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of secretion GO:0051048 37 32 0,000 0,03695984 0,0459855 ! negative regulation of DNA metabolic process GO:0051053 38 32 0,000 0,03695984 0,04596982 ! phosphotransferase activity, phosphate group as acceptor GO:0016776 49 32 0,000 0,03695984 0,04595415 ! meiosis I GO:0007127 53 32 0,000 0,03695984 0,0459385 ! GPI anchor biosynthetic process GO:0006506 35 32 0,000 0,03695984 0,04592285 GO:0006505|GPI anchor metabolic process, ! unsaturated fatty acid biosynthetic process GO:0006636 33 32 0,000 0,03695984 0,04590721 ! sterol biosynthetic process GO:0016126 40 32 0,000 0,03695984 0,04589159 ! vesicle coat GO:0030120 39 32 0,000 0,03695984 0,04587597 ! cytokine production GO:0001816 32 32 0,000 0,03695984 0,04586037 ! regulation of calcium ion transport GO:0051924 37 32 0,000 0,03695984 0,04584478 ! proteoglycan metabolic process GO:0006029 34 32 0,000 0,03695984 0,04582919 ! sphingoid metabolic process GO:0046519 33 32 0,000 0,03695984 0,04581362 ! multicellular organismal metabolic process GO:0044236 35 32 0,000 0,03695984 0,04579806 ! oxygen binding GO:0019825 33 32 0,000 0,03695984 0,04578251 ! leukocyte chemotaxis GO:0030595 32 32 0,000 0,03695984 0,04576697 GO:0060326|cell chemotaxis, ! negative regulation of leukocyte activation GO:0002695 35 32 0,000 0,03695984 0,04575144 ! hormone biosynthetic process GO:0042446 32 32 0,000 0,03695984 0,04573592 ! double-stranded RNA binding GO:0003725 35 32 0,000 0,03695984 0,04572041 ! platelet alpha granule lumen GO:0031093 35 33 0,000 0,03809355 0,04710688 ! DNA helicase activity GO:0003678 55 33 0,000 0,03809355 0,04709091 ! neural tube development GO:0021915 37 33 0,000 0,03809355 0,04707496 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 33 0,000 0,03809355 0,04705902 ! pigment biosynthetic process GO:0046148 35 33 0,000 0,03809355 0,04704309 ! organelle envelope lumen GO:0031970 46 33 0,000 0,03809355 0,04702717 ! negative regulation of DNA binding GO:0043392 39 33 0,000 0,03809355 0,04701126 ! NAD or NADH binding GO:0051287 36 33 0,000 0,03809355 0,04699536 ! nucleotide catabolic process GO:0009166 35 33 0,000 0,03809355 0,04697947 ! B cell differentiation GO:0030183 37 33 0,000 0,03809355 0,0469636 ! regulation of Wnt receptor signaling pathway GO:0030111 36 33 0,000 0,03809355 0,04694773 ! aerobic respiration GO:0009060 35 33 0,000 0,03809355 0,04693188 ! embryonic organ development GO:0048568 41 33 0,000 0,03809355 0,04691603 ! placenta development GO:0001890 39 33 0,000 0,03809355 0,0469002 ! protein serine/threonine phosphatase complex GO:0008287 37 33 0,000 0,03809355 0,04688437 ! tissue remodeling GO:0048771 37 33 0,000 0,03809355 0,04686856 ! flagellum GO:0019861 34 33 0,000 0,03809355 0,04685276 ! L-amino acid transmembrane transporter activity GO:0015179 37 33 0,000 0,03809355 0,04683697 ! Rho protein signal transduction GO:0007266 35 33 0,000 0,03809355 0,04682119 ! odontogenesis GO:0042476 39 34 0,000 0,039226 0,04819684 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,039226 0,04818062 ! lipid homeostasis GO:0055088 37 34 0,000 0,039226 0,0481644 ! telencephalon development GO:0021537 36 34 0,000 0,039226 0,04814819 ! clathrin coat GO:0030118 41 34 0,000 0,039226 0,048132 ! cell growth GO:0016049 36 34 0,000 0,039226 0,04811581 ! protein polymerization GO:0051258 38 34 0,000 0,039226 0,04809964 ! condensed chromosome kinetochore GO:0000777 52 34 0,000 0,039226 0,04808348 ! learning GO:0007612 51 34 0,000 0,039226 0,04806733 ! keratinization GO:0031424 40 34 0,000 0,039226 0,04805119 ! ovulation cycle process GO:0022602 35 34 0,000 0,039226 0,04803506 ! regulation of striated muscle tissue development GO:0016202 40 34 0,000 0,039226 0,04801894 ! regulation of protein import into nucleus GO:0042306 36 34 0,000 0,039226 0,04800283 ! erythrocyte homeostasis GO:0034101 40 34 0,000 0,039226 0,04798673 ! amino acid binding GO:0016597 40 34 0,000 0,039226 0,04797064 ! regulation of protein stability GO:0031647 35 34 0,000 0,039226 0,04795457 ! specific RNA polymerase II transcription factor activity GO:0003704 41 34 0,000 0,039226 0,0479385 ! glycogen metabolic process GO:0005977 48 34 0,000 0,039226 0,04792245 ! pyrimidine nucleotide metabolic process GO:0006220 41 34 0,000 0,039226 0,04790641 ! acetylglucosaminyltransferase activity GO:0008375 40 34 0,000 0,039226 0,04789037 ! epithelial tube morphogenesis GO:0060562 38 34 0,000 0,039226 0,04787435 ! positive regulation of transcription factor activity GO:0051091 49 35 0,000 0,04035716 0,04923844 GO:0090047|positive regulation of transcription regulator activity, ! inner ear morphogenesis GO:0042472 46 35 0,000 0,04035716 0,04922198 ! MHC protein complex GO:0042611 50 35 0,000 0,04035716 0,04920553 ! alcohol biosynthetic process GO:0046165 41 35 0,000 0,04035716 0,04918909 ! vesicle lumen GO:0031983 38 35 0,000 0,04035716 0,04917266 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! female gonad development GO:0008585 37 35 0,000 0,04035716 0,04915624 ! mesenchymal cell development GO:0014031 40 35 0,000 0,04035716 0,04913983 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! neutral lipid metabolic process GO:0006638 47 35 0,000 0,04035716 0,04912344 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 37 35 0,000 0,04035716 0,04910705 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 41 35 0,000 0,04035716 0,04909068 ! ovulation cycle GO:0042698 37 35 0,000 0,04035716 0,04907431 ! intramolecular oxidoreductase activity GO:0016860 35 35 0,000 0,04035716 0,04905796 ! positive regulation of catabolic process GO:0009896 38 35 0,000 0,04035716 0,04904162 ! collagen GO:0005581 54 35 0,000 0,04035716 0,04902529 ! glucan metabolic process GO:0044042 49 35 0,000 0,04035716 0,04900897 GO:0006073|cellular glucan metabolic process, ! regulation of muscle development GO:0048634 42 35 0,000 0,04035716 0,04899266 ! ER to Golgi vesicle-mediated transport GO:0006888 43 35 0,000 0,04035716 0,04897636 ! histone methyltransferase activity GO:0042054 40 35 0,000 0,04035716 0,04896007 ! cation:sugar symporter activity GO:0005402 37 35 0,000 0,04035716 0,0489438 GO:0005351|sugar:hydrogen symporter activity, ! carbohydrate homeostasis GO:0033500 49 35 0,000 0,04035716 0,04892753 GO:0042593|glucose homeostasis, ! cytosolic small ribosomal subunit GO:0022627 36 35 0,000 0,04035716 0,04891127 ! maintenance of protein location GO:0045185 45 35 0,000 0,04035716 0,04889503 ! polyol metabolic process GO:0019751 46 35 0,000 0,04035716 0,0488788 ! O-acyltransferase activity GO:0008374 36 35 0,000 0,04035716 0,04886257 ! purinergic nucleotide receptor activity GO:0001614 40 36 0,000 0,04148706 0,05021394 GO:0016502|nucleotide receptor activity, ! mitochondrial respiratory chain complex I GO:0005747 37 36 0,000 0,04148706 0,05019728 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 42 36 0,000 0,04148706 0,05018064 ! positive regulation of neurogenesis GO:0050769 38 36 0,000 0,04148706 0,05016401 ! SMAD binding GO:0046332 39 36 0,000 0,04148706 0,05014738 ! negative regulation of cell activation GO:0050866 40 36 0,000 0,04148706 0,05013077 ! inositol or phosphatidylinositol kinase activity GO:0004428 51 36 0,000 0,04148706 0,05011417 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 36 0,000 0,04148706 0,05009759 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 38 36 0,000 0,04148706 0,05008101 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 36 0,000 0,04148706 0,05006444 ! hormone-mediated signaling GO:0009755 41 36 0,000 0,04148706 0,05004789 ! nucleus organization GO:0006997 42 36 0,000 0,04148706 0,05003134 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 42 36 0,000 0,04148706 0,05001481 ! carboxypeptidase activity GO:0004180 37 36 0,000 0,04148706 0,04999828 ! energy coupled proton transport, down electrochemical gradient GO:0015985 37 36 0,000 0,04148706 0,04998177 GO:0015986|ATP synthesis coupled proton transport, ! female gamete generation GO:0007292 39 36 0,000 0,04148706 0,04996527 ! maintenance of location in cell GO:0051651 38 36 0,000 0,04148706 0,04994878 ! activation of adenylate cyclase activity GO:0007190 44 37 0,000 0,04261569 0,05129068 ! regulation of hormone secretion GO:0046883 43 37 0,000 0,04261569 0,05127376 ! sugar transmembrane transporter activity GO:0051119 39 37 0,000 0,04261569 0,05125685 GO:0015144|carbohydrate transmembrane transporter activity, ! regulation of Rab protein signal transduction GO:0032483 40 37 0,000 0,04261569 0,05123996 GO:0032313|regulation of Rab GTPase activity, ! regulation of action potential in neuron GO:0019228 44 37 0,000 0,04261569 0,05122308 ! glycerol ether metabolic process GO:0006662 49 37 0,000 0,04261569 0,05120621 ! endoribonuclease activity GO:0004521 48 37 0,000 0,04261569 0,05118934 ! hindbrain development GO:0030902 43 37 0,000 0,04261569 0,0511725 ! isoprenoid metabolic process GO:0006720 41 37 0,000 0,04261569 0,05115566 ! pigmentation GO:0043473 51 37 0,000 0,04261569 0,05113883 ! regulation of neuron projection development GO:0010975 43 37 0,000 0,04261569 0,05112201 ! condensed chromosome, centromeric region GO:0000779 55 37 0,000 0,04261569 0,05110521 ! metalloexopeptidase activity GO:0008235 39 37 0,000 0,04261569 0,05108841 ! monocarboxylic acid transport GO:0015718 43 37 0,000 0,04261569 0,05107163 ! sensory perception of taste GO:0050909 37 37 0,000 0,04261569 0,05105486 ! cell junction organization GO:0034330 44 37 0,000 0,04261569 0,0510381 ! skeletal muscle fiber development GO:0048741 41 37 0,000 0,04261569 0,05102135 ! development of primary female sexual characteristics GO:0046545 40 37 0,000 0,04261569 0,05100461 GO:0046660|female sex differentiation, ! NADH dehydrogenase (ubiquinone) activity GO:0008137 38 37 0,000 0,04261569 0,05098788 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! ion transmembrane transport GO:0034220 38 37 0,000 0,04261569 0,05097116 ! regulation of lymphocyte mediated immunity GO:0002706 43 37 0,000 0,04261569 0,05095445 ! coated pit GO:0005905 44 37 0,000 0,04261569 0,05093776 ! positive regulation of adenylate cyclase activity GO:0045762 45 38 0,000 0,04374305 0,05226815 ! regulation of translational initiation GO:0006446 50 38 0,000 0,04374305 0,05225103 ! negative regulation of binding GO:0051100 44 38 0,000 0,04374305 0,05223393 ! organic ether metabolic process GO:0018904 50 38 0,000 0,04374305 0,05221683 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 43 38 0,000 0,04374305 0,05219975 ! regulation of lymphocyte differentiation GO:0045619 51 38 0,000 0,04374305 0,05218268 ! carbon-carbon lyase activity GO:0016830 41 38 0,000 0,04374305 0,05216562 ! hydro-lyase activity GO:0016836 44 38 0,000 0,04374305 0,05214858 ! synapse organization GO:0050808 43 38 0,000 0,04374305 0,05213154 ! viral infectious cycle GO:0019058 40 38 0,000 0,04374305 0,05211452 ! phosphoinositide biosynthetic process GO:0046489 41 38 0,000 0,04374305 0,0520975 ! negative regulation of protein complex disassembly GO:0043242 42 38 0,000 0,04374305 0,0520805 ! organic anion transport GO:0015711 42 38 0,000 0,04374305 0,05206351 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 52 38 0,000 0,04374305 0,05204653 ! monosaccharide binding GO:0048029 41 38 0,000 0,04374305 0,05202956 ! muscle fiber development GO:0048747 42 38 0,000 0,04374305 0,0520126 ! development of primary male sexual characteristics GO:0046546 46 38 0,000 0,04374305 0,05199565 ! phagocytosis GO:0006909 44 38 0,000 0,04374305 0,05197871 ! regulation of ARF protein signal transduction GO:0032012 44 38 0,000 0,04374305 0,05196179 ! general RNA polymerase II transcription factor activity GO:0016251 43 38 0,000 0,04374305 0,05194487 ! DNA-directed RNA polymerase activity GO:0003899 49 38 0,000 0,04374305 0,05192797 GO:0034062|RNA polymerase activity, ! extrinsic to plasma membrane GO:0019897 43 38 0,000 0,04374305 0,05191108 ! cytosolic large ribosomal subunit GO:0022625 43 38 0,000 0,04374305 0,05189419 ! Rab GTPase activator activity GO:0005097 41 38 0,000 0,04374305 0,05187732 ! cellular response to insulin stimulus GO:0032869 47 38 0,000 0,04374305 0,05186046 ! monocarboxylic acid binding GO:0033293 44 39 0,000 0,04486914 0,05317824 ! induction of apoptosis by extracellular signals GO:0008624 44 39 0,000 0,04486914 0,05316097 ! heterocycle biosynthetic process GO:0018130 51 39 0,000 0,04486914 0,05314371 ! positive regulation of DNA binding GO:0043388 53 39 0,000 0,04486914 0,05312646 ! T cell differentiation GO:0030217 64 39 0,000 0,04486914 0,05310922 ! DNA-dependent ATPase activity GO:0008094 63 39 0,000 0,04486914 0,053092 ! cell fate specification GO:0001708 55 39 0,000 0,04486914 0,05307478 ! positive regulation of cyclase activity GO:0031281 46 39 0,000 0,04486914 0,05305758 ! regulation of adaptive immune response GO:0002819 44 39 0,000 0,04486914 0,05304039 ! regulation of cell morphogenesis involved in differentiation GO:0010769 45 39 0,000 0,04486914 0,0530232 ! receptor-mediated endocytosis GO:0006898 44 39 0,000 0,04486914 0,05300603 ! regulation of metal ion transport GO:0010959 45 39 0,000 0,04486914 0,05298887 ! energy reserve metabolic process GO:0006112 53 39 0,000 0,04486914 0,05297173 ! amine receptor activity GO:0008227 48 39 0,000 0,04486914 0,05295459 ! cytoskeleton-dependent intracellular transport GO:0030705 42 39 0,000 0,04486914 0,05293746 ! embryonic skeletal system morphogenesis GO:0048704 46 39 0,000 0,04486914 0,05292035 ! neuropeptide receptor activity GO:0008188 41 39 0,000 0,04486914 0,05290324 ! pigment metabolic process GO:0042440 43 39 0,000 0,04486914 0,05288615 ! RNA modification GO:0009451 39 39 0,000 0,04486914 0,05286907 ! regulation of intracellular protein transport GO:0033157 43 40 0,000 0,04599397 0,05417694 ! peroxisomal membrane GO:0005778 44 40 0,000 0,04599397 0,05415946 GO:0031903|microbody membrane, ! actin filament binding GO:0051015 41 40 0,000 0,04599397 0,05414198 ! positive regulation of cell development GO:0010720 43 40 0,000 0,04599397 0,05412452 ! ribonucleoside metabolic process GO:0009119 47 40 0,000 0,04599397 0,05410706 ! biopolymer methylation GO:0043414 45 40 0,000 0,04599397 0,05408962 ! neuron migration GO:0001764 43 40 0,000 0,04599397 0,05407219 ! regulation of protein secretion GO:0050708 45 40 0,000 0,04599397 0,05405477 ! oxidoreduction coenzyme metabolic process GO:0006733 45 40 0,000 0,04599397 0,05403736 ! dorsal/ventral pattern formation GO:0009953 42 40 0,000 0,04599397 0,05401996 ! regulation of actin filament polymerization GO:0030833 53 40 0,000 0,04599397 0,05400257 ! positive regulation of defense response GO:0031349 41 40 0,000 0,04599397 0,0539852 ! mammary gland development GO:0030879 47 40 0,000 0,04599397 0,05396783 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 50 40 0,000 0,04599397 0,05395048 ! neuropeptide binding GO:0042923 42 40 0,000 0,04599397 0,05393314 ! regulation of tube size GO:0035150 44 40 0,000 0,04599397 0,05391581 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 42 40 0,000 0,04599397 0,05389849 ! positive regulation of gene-specific transcription GO:0043193 46 40 0,000 0,04599397 0,05388118 ! regulation of leukocyte mediated immunity GO:0002703 46 40 0,000 0,04599397 0,05386388 ! inorganic anion transmembrane transporter activity GO:0015103 43 40 0,000 0,04599397 0,0538466 ! chromatin remodeling GO:0006338 44 40 0,000 0,04599397 0,05382932 ! solute:hydrogen symporter activity GO:0015295 44 40 0,000 0,04599397 0,05381206 ! protein amino acid N-linked glycosylation GO:0006487 46 41 0,000 0,04711753 0,05510893 ! Notch signaling pathway GO:0007219 46 41 0,000 0,04711753 0,05509127 ! keratin filament GO:0045095 44 41 0,000 0,04711753 0,05507361 ! peptide metabolic process GO:0006518 42 41 0,000 0,04711753 0,05505597 ! polysaccharide biosynthetic process GO:0000271 42 41 0,000 0,04711753 0,05503834 ! late endosome membrane GO:0031902 45 41 0,000 0,04711753 0,05502073 ! icosanoid metabolic process GO:0006690 51 41 0,000 0,04711753 0,05500312 ! positive regulation of lyase activity GO:0051349 48 41 0,000 0,04711753 0,05498552 ! integral to endoplasmic reticulum membrane GO:0030176 43 41 0,000 0,04711753 0,05496794 ! glycolysis GO:0006096 43 41 0,000 0,04711753 0,05495037 ! branching morphogenesis of a tube GO:0048754 54 41 0,000 0,04711753 0,05493281 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 51 41 0,000 0,04711753 0,05491526 ! proton-transporting two-sector ATPase complex GO:0016469 42 41 0,000 0,04711753 0,05489772 ! response to reactive oxygen species GO:0000302 49 42 0,000 0,04823983 0,05618739 ! cellular amide metabolic process GO:0043603 56 42 0,000 0,04823983 0,05616945 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 43 42 0,000 0,04823983 0,05615153 ! ER-Golgi intermediate compartment GO:0005793 52 42 0,000 0,04823983 0,05613362 ! regulation of multicellular organism growth GO:0040014 46 42 0,000 0,04823983 0,05611572 ! integral to Golgi membrane GO:0030173 55 42 0,000 0,04823983 0,05609783 ! developmental growth GO:0048589 45 42 0,000 0,04823983 0,05607995 ! structural constituent of muscle GO:0008307 46 42 0,000 0,04823983 0,05606209 ! mitochondrial transport GO:0006839 45 42 0,000 0,04823983 0,05604423 ! protein methyltransferase activity GO:0008276 49 42 0,000 0,04823983 0,05602639 ! metal cluster binding GO:0051540 47 42 0,000 0,04823983 0,05600856 GO:0051536|iron-sulfur cluster binding, ! feeding behavior GO:0007631 48 42 0,000 0,04823983 0,05599074 ! ribonucleoprotein complex assembly GO:0022618 47 42 0,000 0,04823983 0,05597293 ! RNA catabolic process GO:0006401 49 43 0,000 0,04936087 0,05725546 ! ear morphogenesis GO:0042471 56 43 0,000 0,04936087 0,05723727 ! cellular amino acid biosynthetic process GO:0008652 49 43 0,000 0,04936087 0,05721908 ! regulation of epithelial cell proliferation GO:0050678 50 43 0,000 0,04936087 0,0572009 ! positive regulation of growth GO:0045927 47 43 0,000 0,04936087 0,05718274 ! cell recognition GO:0008037 51 43 0,000 0,04936087 0,05716458 ! positive regulation of cytokine production GO:0001819 46 43 0,000 0,04936087 0,05714644 ! epithelial cell differentiation GO:0030855 56 43 0,000 0,04936087 0,05712831 ! gliogenesis GO:0042063 46 43 0,000 0,04936087 0,05711019 ! endosome transport GO:0016197 48 43 0,000 0,04936087 0,05709209 ! striated muscle contraction GO:0006941 45 43 0,000 0,04936087 0,05707399 ! positive regulation of cytokine biosynthetic process GO:0042108 48 43 0,000 0,04936087 0,05705591 ! antioxidant activity GO:0016209 53 43 0,000 0,04936087 0,05703783 ! sulfur compound biosynthetic process GO:0044272 47 43 0,000 0,04936087 0,05701977 ! activation of caspase activity GO:0006919 60 43 0,000 0,04936087 0,05700172 ! vascular process in circulatory system GO:0003018 48 43 0,000 0,04936087 0,05698368 ! histone modification GO:0016570 45 43 0,000 0,04936087 0,05696566 ! cellular amino acid derivative biosynthetic process GO:0042398 55 43 0,000 0,04936087 0,05694764 ! regulation of nucleocytoplasmic transport GO:0046822 46 44 0,000 0,05048064 0,05822111 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 50 44 0,000 0,05048064 0,05820271 ! negative regulation of cell migration GO:0030336 53 44 0,000 0,05048064 0,05818432 ! ATP synthesis coupled electron transport GO:0042773 45 44 0,000 0,05048064 0,05816594 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! nucleoside monophosphate biosynthetic process GO:0009124 50 44 0,000 0,05048064 0,05814758 ! chemokine activity GO:0008009 48 44 0,000 0,05048064 0,05812922 ! ruffle GO:0001726 50 44 0,000 0,05048064 0,05811088 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 51 44 0,000 0,05048064 0,05809255 ! regulation of neuron apoptosis GO:0043523 58 44 0,000 0,05048064 0,05807423 ! cartilage development GO:0051216 48 44 0,000 0,05048064 0,05805592 ! membrane fusion GO:0006944 52 44 0,000 0,05048064 0,05803762 ! channel regulator activity GO:0016247 54 44 0,000 0,05048064 0,05801934 ! excretion GO:0007588 53 44 0,000 0,05048064 0,05800106 ! male sex differentiation GO:0046661 52 44 0,000 0,05048064 0,0579828 ! protein phosphatase regulator activity GO:0019888 50 44 0,000 0,05048064 0,05796455 ! RNA elongation from RNA polymerase II promoter GO:0006368 49 44 0,000 0,05048064 0,05794631 ! amino acid activation GO:0043038 45 44 0,000 0,05048064 0,05792808 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! microbody part GO:0044438 48 44 0,000 0,05048064 0,05790987 GO:0044439|peroxisomal part, ! positive regulation of binding GO:0051099 59 45 0,000 0,05159916 0,05917439 ! solute:sodium symporter activity GO:0015370 51 45 0,000 0,05159916 0,05915579 ! transferase activity, transferring pentosyl groups GO:0016763 50 45 0,000 0,05159916 0,05913721 ! organellar ribosome GO:0000313 46 45 0,000 0,05159916 0,05911863 GO:0005761|mitochondrial ribosome, ! platelet alpha granule GO:0031091 49 45 0,000 0,05159916 0,05910007 ! single-stranded DNA binding GO:0003697 48 45 0,000 0,05159916 0,05908152 ! intrinsic to Golgi membrane GO:0031228 60 45 0,000 0,05159916 0,05906298 ! transport vesicle GO:0030133 53 45 0,000 0,05159916 0,05904446 ! regulation of endocytosis GO:0030100 52 45 0,000 0,05159916 0,05902594 ! ligase activity, forming carbon-oxygen bonds GO:0016875 47 45 0,000 0,05159916 0,05900744 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! regulation of protein complex disassembly GO:0043244 49 45 0,000 0,05159916 0,05898895 ! nuclear matrix GO:0016363 56 45 0,000 0,05159916 0,05897047 ! unsaturated fatty acid metabolic process GO:0033559 55 45 0,000 0,05159916 0,058952 ! regulation of T cell proliferation GO:0042129 53 45 0,000 0,05159916 0,05893354 ! regulation of myeloid leukocyte differentiation GO:0002761 54 45 0,000 0,05159916 0,0589151 ! DNA-dependent DNA replication GO:0006261 66 45 0,000 0,05159916 0,05889666 ! coated vesicle membrane GO:0030662 52 45 0,000 0,05159916 0,05887824 ! covalent chromatin modification GO:0016569 47 45 0,000 0,05159916 0,05885983 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 51 45 0,000 0,05159916 0,05884143 ! synaptosome GO:0019717 50 45 0,000 0,05159916 0,05882304 ! chemokine receptor binding GO:0042379 50 45 0,000 0,05159916 0,05880466 ! regulation of action potential GO:0001508 56 46 0,000 0,05271642 0,06005918 ! immunoglobulin mediated immune response GO:0016064 51 46 0,000 0,05271642 0,06004043 ! phosphatase regulator activity GO:0019208 53 46 0,000 0,05271642 0,06002169 ! regulation of inflammatory response GO:0050727 49 46 0,000 0,05271642 0,06000296 ! eye morphogenesis GO:0048592 57 46 0,000 0,05271642 0,05998425 ! regulation of JNK cascade GO:0046328 53 46 0,000 0,05271642 0,05996554 ! methylation GO:0032259 51 46 0,000 0,05271642 0,05994685 ! positive regulation of protein transport GO:0051222 50 46 0,000 0,05271642 0,05992817 ! regulation of ion transport GO:0043269 54 46 0,000 0,05271642 0,0599095 ! leukocyte migration GO:0050900 49 46 0,000 0,05271642 0,05989084 ! neuromuscular process GO:0050905 56 46 0,000 0,05271642 0,0598722 ! sulfotransferase activity GO:0008146 54 46 0,000 0,05271642 0,05985356 ! JNK cascade GO:0007254 48 46 0,000 0,05271642 0,05983494 ! SH3/SH2 adaptor activity GO:0005070 52 46 0,000 0,05271642 0,05981633 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 54 47 0,000 0,05383242 0,06106364 ! auxiliary transport protein activity GO:0015457 58 47 0,000 0,05383242 0,06104466 ! regulation of actin polymerization or depolymerization GO:0008064 60 47 0,000 0,05383242 0,06102569 ! morphogenesis of a branching structure GO:0001763 70 47 0,000 0,05383242 0,06100673 ! carbon-oxygen lyase activity GO:0016835 53 47 0,000 0,05383242 0,06098779 ! regulation of protein polymerization GO:0032271 60 47 0,000 0,05383242 0,06096885 ! viral reproductive process GO:0022415 53 47 0,000 0,05383242 0,06094993 ! RNA elongation GO:0006354 52 47 0,000 0,05383242 0,06093102 ! negative regulation of immune system process GO:0002683 58 47 0,000 0,05383242 0,06091212 ! mRNA binding GO:0003729 65 47 0,000 0,05383242 0,06089323 ! axon GO:0030424 53 48 0,000 0,05494717 0,06213493 ! protein amino acid lipidation GO:0006497 53 48 0,000 0,05494717 0,06211567 ! stress-activated protein kinase signaling pathway GO:0031098 50 48 0,000 0,05494717 0,06209643 ! proteasome complex GO:0000502 50 48 0,000 0,05494717 0,0620772 ! glutamine family amino acid metabolic process GO:0009064 62 48 0,000 0,05494717 0,06205798 ! protein homooligomerization GO:0051260 63 48 0,000 0,05494717 0,06203877 ! regulation of cell projection organization GO:0031344 54 48 0,000 0,05494717 0,06201958 ! kinetochore GO:0000776 69 48 0,000 0,05494717 0,06200039 ! positive regulation of caspase activity GO:0043280 65 48 0,000 0,05494717 0,06198122 GO:0010952|positive regulation of peptidase activity, ! detection of stimulus involved in sensory perception GO:0050906 53 48 0,000 0,05494717 0,06196206 ! growth factor receptor binding GO:0070851 58 48 0,000 0,05494717 0,06194291 ! N-methyltransferase activity GO:0008170 53 48 0,000 0,05494717 0,06192378 ! inner ear development GO:0048839 60 48 0,000 0,05494717 0,06190465 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 57 48 0,000 0,05494717 0,06188554 ! amino acid transmembrane transporter activity GO:0015171 53 48 0,000 0,05494717 0,06186644 ! chromatin remodeling complex GO:0016585 54 48 0,000 0,05494717 0,06184735 ! B cell mediated immunity GO:0019724 53 48 0,000 0,05494717 0,06182828 ! steroid hormone receptor activity GO:0003707 61 48 0,000 0,05494717 0,06180921 ! regulation of cell shape GO:0008360 55 48 0,000 0,05494717 0,06179016 ! cell cortex part GO:0044448 54 48 0,000 0,05494717 0,06177112 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 52 49 0,000 0,05606066 0,06300348 ! regulation of neurotransmitter levels GO:0001505 55 49 0,000 0,05606066 0,06298408 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 54 49 0,000 0,05606066 0,06296469 ! response to temperature stimulus GO:0009266 57 49 0,000 0,05606066 0,06294531 ! Golgi-associated vesicle GO:0005798 59 49 0,000 0,05606066 0,06292594 ! lipid modification GO:0030258 55 49 0,000 0,05606066 0,06290658 ! synaptic vesicle GO:0008021 56 49 0,000 0,05606066 0,06288724 ! pyridoxal phosphate binding GO:0030170 63 49 0,000 0,05606066 0,06286791 GO:0070279|vitamin B6 binding, ! exonuclease activity GO:0004527 79 49 0,000 0,05606066 0,06284859 ! maintenance of location GO:0051235 62 49 0,000 0,05606066 0,06282928 ! negative regulation of cell motion GO:0051271 60 49 0,000 0,05606066 0,06280998 ! regulation of actin filament length GO:0030832 62 49 0,000 0,05606066 0,0627907 ! nuclear periphery GO:0034399 60 49 0,000 0,05606066 0,06277142 ! regulation of muscle contraction GO:0006937 57 49 0,000 0,05606066 0,06275216 ! nucleotide-excision repair GO:0006289 53 49 0,000 0,05606066 0,06273291 ! respiratory electron transport chain GO:0022904 51 50 0,000 0,0571729 0,06395791 ! cytokine-mediated signaling pathway GO:0019221 56 50 0,000 0,0571729 0,06393831 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,0571729 0,06391871 ! embryonic skeletal system development GO:0048706 59 50 0,000 0,0571729 0,06389913 ! glucose catabolic process GO:0006007 54 50 0,000 0,0571729 0,06387956 ! aging GO:0007568 92 50 0,000 0,0571729 0,06386 ! generation of a signal involved in cell-cell signaling GO:0003001 59 50 0,000 0,0571729 0,06384045 ! heart morphogenesis GO:0003007 57 50 0,000 0,0571729 0,06382092 ! integrin binding GO:0005178 56 50 0,000 0,0571729 0,06380139 ! detection of abiotic stimulus GO:0009582 56 50 0,000 0,0571729 0,06378188 ! regulation of angiogenesis GO:0045765 56 51 0,000 0,0582839 0,06500142 ! positive regulation of cell migration GO:0030335 63 51 0,000 0,0582839 0,06498156 ! regulation of ossification GO:0030278 59 51 0,000 0,0582839 0,0649617 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 60 51 0,000 0,0582839 0,06494186 ! cellular polysaccharide metabolic process GO:0044264 65 51 0,000 0,0582839 0,06492203 ! endocrine system development GO:0035270 55 51 0,000 0,0582839 0,06490221 ! germ cell development GO:0007281 56 51 0,000 0,0582839 0,06488241 ! transferase activity, transferring sulfur-containing groups GO:0016782 60 52 0,000 0,05939364 0,06609762 ! regulation of cellular component size GO:0032535 66 52 0,000 0,05939364 0,06607746 ! carbohydrate transport GO:0008643 57 52 0,000 0,05939364 0,06605731 ! ubiquitin thiolesterase activity GO:0004221 64 52 0,000 0,05939364 0,06603718 ! nucleoside monophosphate metabolic process GO:0009123 58 52 0,000 0,05939364 0,06601706 ! cell maturation GO:0048469 68 52 0,000 0,05939364 0,06599695 ! regulation of intracellular transport GO:0032386 57 52 0,000 0,05939364 0,06597685 ! vesicle organization GO:0016050 59 52 0,000 0,05939364 0,06595677 ! kidney development GO:0001822 55 52 0,000 0,05939364 0,0659367 ! cellular component disassembly GO:0022411 69 52 0,000 0,05939364 0,06591664 ! cell redox homeostasis GO:0045454 57 52 0,000 0,05939364 0,06589659 ! lipoprotein biosynthetic process GO:0042158 57 52 0,000 0,05939364 0,06587655 ! lipid transporter activity GO:0005319 58 52 0,000 0,05939364 0,06585653 ! cytokine receptor activity GO:0004896 54 52 0,000 0,05939364 0,06583652 ! antiporter activity GO:0015297 53 52 0,000 0,05939364 0,06581652 ! embryonic limb morphogenesis GO:0030326 62 53 0,000 0,06050213 0,06702453 GO:0035113|embryonic appendage morphogenesis, ! glycosaminoglycan metabolic process GO:0030203 60 53 0,000 0,06050213 0,06700418 ! keratinocyte differentiation GO:0030216 60 53 0,000 0,06050213 0,06698384 ! N-acetyltransferase activity GO:0008080 59 53 0,000 0,06050213 0,06696352 ! basement membrane GO:0005604 55 53 0,000 0,06050213 0,06694321 ! water-soluble vitamin metabolic process GO:0006767 59 53 0,000 0,06050213 0,06692291 ! negative regulation of response to stimulus GO:0048585 68 53 0,000 0,06050213 0,06690263 ! viral reproduction GO:0016032 59 53 0,000 0,06050213 0,06688235 ! chloride transport GO:0006821 60 53 0,000 0,06050213 0,06686209 ! oxygen and reactive oxygen species metabolic process GO:0006800 58 53 0,000 0,06050213 0,06684184 ! DNA catabolic process GO:0006308 57 53 0,000 0,06050213 0,06682161 ! heterocycle catabolic process GO:0046700 56 53 0,000 0,06050213 0,06680138 ! integrin-mediated signaling pathway GO:0007229 59 53 0,000 0,06050213 0,06678117 ! single fertilization GO:0007338 58 53 0,000 0,06050213 0,06676097 ! activation of phospholipase C activity GO:0007202 61 54 0,000 0,06160937 0,0679622 GO:0010863|positive regulation of phospholipase C activity, ! double-stranded DNA binding GO:0003690 63 54 0,000 0,06160937 0,06794166 ! mitochondrial respiratory chain GO:0005746 55 54 0,000 0,06160937 0,06792112 ! nucleoside metabolic process GO:0009116 62 54 0,000 0,06160937 0,0679006 ! coated membrane GO:0048475 65 54 0,000 0,06160937 0,0678801 GO:0030117|membrane coat, ! nucleosome GO:0000786 59 54 0,000 0,06160937 0,0678596 ! regulation of protein complex assembly GO:0043254 67 54 0,000 0,06160937 0,06783912 ! cellular defense response GO:0006968 61 54 0,000 0,06160937 0,06781865 ! gastrulation GO:0007369 62 54 0,000 0,06160937 0,06779819 ! dendrite GO:0030425 60 55 0,000 0,06271537 0,06899448 ! positive regulation of phospholipase activity GO:0010518 62 55 0,000 0,06271537 0,06897368 ! respiratory chain GO:0070469 57 55 0,000 0,06271537 0,06895289 ! coenzyme biosynthetic process GO:0009108 68 55 0,000 0,06271537 0,06893211 ! extracellular matrix organization GO:0030198 77 55 0,000 0,06271537 0,06891135 ! positive regulation of cell motion GO:0051272 69 55 0,000 0,06271537 0,0688906 ! protein amino acid autophosphorylation GO:0046777 61 55 0,000 0,06271537 0,06886986 ! translation initiation factor activity GO:0003743 66 55 0,000 0,06271537 0,06884914 ! regulation of bone remodeling GO:0046850 64 56 0,000 0,06382013 0,07004086 ! late endosome GO:0005770 60 56 0,000 0,06382013 0,0700198 ! regulation of phospholipase activity GO:0010517 63 56 0,000 0,06382013 0,06999875 ! sphingolipid metabolic process GO:0006665 60 56 0,000 0,06382013 0,06997771 ! intrinsic to endoplasmic reticulum membrane GO:0031227 61 56 0,000 0,06382013 0,06995668 ! ribonuclease activity GO:0004540 67 56 0,000 0,06382013 0,06993567 ! positive regulation of T cell activation GO:0050870 74 56 0,000 0,06382013 0,06991466 ! mesoderm development GO:0007498 67 56 0,000 0,06382013 0,06989368 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 61 56 0,000 0,06382013 0,0698727 ! antigen processing and presentation GO:0019882 73 56 0,000 0,06382013 0,06985174 ! proton transport GO:0015992 59 56 0,000 0,06382013 0,06983078 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 57 0,000 0,06492364 0,07101693 ! glycerophospholipid biosynthetic process GO:0046474 71 57 0,000 0,06492364 0,07099564 ! diacylglycerol binding GO:0019992 65 57 0,000 0,06492364 0,07097436 ! B cell activation GO:0042113 63 57 0,000 0,06492364 0,0709531 ! small ribosomal subunit GO:0015935 58 57 0,000 0,06492364 0,07093185 ! detection of external stimulus GO:0009581 64 57 0,000 0,06492364 0,07091061 ! occluding junction GO:0070160 75 58 0,000 0,06602591 0,07209295 GO:0005923|tight junction, ! epidermal cell differentiation GO:0009913 66 58 0,000 0,06602591 0,07207137 ! hydrogen transport GO:0006818 61 58 0,000 0,06602591 0,07204982 ! receptor signaling protein serine/threonine kinase activity GO:0004702 64 58 0,000 0,06602591 0,07202827 ! lymphocyte mediated immunity GO:0002449 65 58 0,000 0,06602591 0,07200674 ! response to nutrient GO:0007584 68 58 0,000 0,06602591 0,07198522 ! large ribosomal subunit GO:0015934 64 58 0,000 0,06602591 0,07196371 ! regulation of tissue remodeling GO:0034103 66 58 0,000 0,06602591 0,07194221 ! ligand-dependent nuclear receptor activity GO:0004879 72 58 0,000 0,06602591 0,07192073 ! myosin complex GO:0016459 64 58 0,000 0,06602591 0,07189926 ! regulation of gene-specific transcription GO:0032583 69 59 0,000 0,06712694 0,07307642 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 62 59 0,000 0,06712694 0,07305462 GO:0051213|dioxygenase activity, ! muscle cell differentiation GO:0042692 77 59 0,000 0,06712694 0,07303283 ! actin filament organization GO:0007015 65 59 0,000 0,06712694 0,07301106 ! regulation of heart contraction GO:0008016 71 59 0,000 0,06712694 0,0729893 ! hexose catabolic process GO:0019320 64 59 0,000 0,06712694 0,07296755 ! cellular amino acid catabolic process GO:0009063 63 59 0,000 0,06712694 0,07294581 ! cell projection assembly GO:0030031 79 59 0,000 0,06712694 0,07292409 ! appendage morphogenesis GO:0035107 68 59 0,000 0,06712694 0,07290238 GO:0035108|limb morphogenesis, ! homeostasis of number of cells GO:0048872 67 59 0,000 0,06712694 0,07288068 ! fertilization GO:0009566 65 59 0,000 0,06712694 0,072859 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 62 59 0,000 0,06712694 0,07283733 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 69 59 0,000 0,06712694 0,07281567 ! adult behavior GO:0030534 72 59 0,000 0,06712694 0,07279402 ! positive regulation of secretion GO:0051047 66 60 0,000 0,06822674 0,07396467 ! molecular adaptor activity GO:0060090 73 60 0,000 0,06822674 0,0739427 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 63 60 0,000 0,06822674 0,07392074 ! phosphoinositide metabolic process GO:0030384 68 60 0,000 0,06822674 0,07389879 ! copper ion binding GO:0005507 85 60 0,000 0,06822674 0,07387686 ! positive regulation of lipase activity GO:0060193 68 60 0,000 0,06822674 0,07385493 ! activation of immune response GO:0002253 72 60 0,000 0,06822674 0,07383303 ! appendage development GO:0048736 69 60 0,000 0,06822674 0,07381113 GO:0060173|limb development, ! regulation of vesicle-mediated transport GO:0060627 69 60 0,000 0,06822674 0,07378925 ! secondary metabolic process GO:0019748 67 60 0,000 0,06822674 0,07376738 ! cellular hormone metabolic process GO:0034754 64 61 0,000 0,06932529 0,07493293 ! ear development GO:0043583 76 61 0,000 0,06932529 0,07491074 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 68 61 0,000 0,06932529 0,07488856 ! learning or memory GO:0007611 79 61 0,000 0,06932529 0,07486639 ! Ras GTPase binding GO:0017016 78 61 0,000 0,06932529 0,07484423 ! camera-type eye development GO:0043010 69 61 0,000 0,06932529 0,07482209 ! transcription initiation from RNA polymerase II promoter GO:0006367 69 61 0,000 0,06932529 0,07479996 ! regulation of transcription factor activity GO:0051090 80 62 0,000 0,07042261 0,07596146 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 90 62 0,000 0,07042261 0,07593901 ! lysosomal membrane GO:0005765 69 62 0,000 0,07042261 0,07591657 ! membrane lipid metabolic process GO:0006643 76 62 0,000 0,07042261 0,07589414 ! nuclear pore GO:0005643 79 62 0,000 0,07042261 0,07587173 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 77 62 0,000 0,07042261 0,07584933 ! skeletal system morphogenesis GO:0048705 83 62 0,000 0,07042261 0,07582694 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 77 62 0,000 0,07042261 0,07580456 ! chloride channel activity GO:0005254 72 62 0,000 0,07042261 0,0757822 ! cell soma GO:0043025 68 62 0,000 0,07042261 0,07575985 ! microtubule motor activity GO:0003777 94 62 0,000 0,07042261 0,07573752 ! focal adhesion GO:0005925 72 62 0,000 0,07042261 0,0757152 ! protein maturation by peptide bond cleavage GO:0051605 69 62 0,000 0,07042261 0,07569289 ! FAD binding GO:0050660 71 63 0,000 0,07151869 0,07684836 ! urogenital system development GO:0001655 75 63 0,000 0,07151869 0,07682573 ! regulation of synaptic transmission GO:0050804 79 63 0,000 0,07151869 0,07680311 ! aminoglycan metabolic process GO:0006022 70 63 0,000 0,07151869 0,07678051 ! cAMP-mediated signaling GO:0019933 75 63 0,000 0,07151869 0,07675792 ! amine transmembrane transporter activity GO:0005275 69 63 0,000 0,07151869 0,07673535 ! regulation of immune effector process GO:0002697 81 63 0,000 0,07151869 0,07671278 ! respiratory tube development GO:0030323 92 64 0,000 0,07261354 0,07786425 ! intracellular protein transmembrane transport GO:0065002 83 64 0,000 0,07261354 0,07784137 ! tRNA processing GO:0008033 73 64 0,000 0,07261354 0,0778185 ! negative regulation of ligase activity GO:0051352 79 64 0,000 0,07261354 0,07779565 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of myeloid cell differentiation GO:0045637 77 64 0,000 0,07261354 0,07777281 ! adaptive immune response GO:0002250 70 64 0,000 0,07261354 0,07774998 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! transition metal ion transport GO:0000041 74 64 0,000 0,07261354 0,07772717 ! neurotransmitter transport GO:0006836 72 64 0,000 0,07261354 0,07770437 ! N-acyltransferase activity GO:0016410 70 64 0,000 0,07261354 0,07768158 ! multicellular organism reproduction GO:0032504 71 65 0,000 0,07370715 0,07882841 GO:0048609|reproductive process in a multicellular organism, ! lymphocyte differentiation GO:0030098 93 65 0,000 0,07370715 0,0788053 ! regulation of cytokine biosynthetic process GO:0042035 84 65 0,000 0,07370715 0,07878221 ! activation of MAPK activity GO:0000187 74 65 0,000 0,07370715 0,07875914 ! gonad development GO:0008406 71 65 0,000 0,07370715 0,07873607 ! acetyltransferase activity GO:0016407 73 65 0,000 0,07370715 0,07871303 ! protein import into nucleus GO:0006606 73 66 0,000 0,07479954 0,07985622 ! developmental maturation GO:0021700 85 66 0,000 0,07479954 0,07983286 ! myeloid cell differentiation GO:0030099 78 66 0,000 0,07479954 0,07980951 ! leukocyte mediated immunity GO:0002443 73 66 0,000 0,07479954 0,07978617 ! tube morphogenesis GO:0035239 84 66 0,000 0,07479954 0,07976285 ! cysteine-type endopeptidase activity GO:0004197 73 66 0,000 0,07479954 0,07973954 ! cell-substrate adherens junction GO:0005924 76 66 0,000 0,07479954 0,07971625 ! endoplasmic reticulum lumen GO:0005788 78 67 0,000 0,07589069 0,08085551 ! glycerolipid biosynthetic process GO:0045017 81 67 0,000 0,07589069 0,0808319 ! nuclear import GO:0051170 74 67 0,000 0,07589069 0,0808083 ! activation of protein kinase activity GO:0032147 83 67 0,000 0,07589069 0,08078472 ! chloride ion binding GO:0031404 79 67 0,000 0,07589069 0,08076116 ! humoral immune response GO:0006959 75 67 0,000 0,07589069 0,08073761 ! amine binding GO:0043176 77 67 0,000 0,07589069 0,08071407 ! female pregnancy GO:0007565 78 67 0,000 0,07589069 0,08069054 ! extrinsic to membrane GO:0019898 75 67 0,000 0,07589069 0,08066703 ! anion channel activity GO:0005253 77 67 0,000 0,07589069 0,08064353 ! regulation of homeostatic process GO:0032844 88 67 0,000 0,07589069 0,08062005 ! regulation of adenylate cyclase activity GO:0045761 81 68 0,000 0,07698062 0,08175409 ! amine catabolic process GO:0009310 73 68 0,000 0,07698062 0,0817303 ! monosaccharide catabolic process GO:0046365 73 68 0,000 0,07698062 0,08170652 ! cell-substrate junction GO:0030055 78 68 0,000 0,07698062 0,08168275 ! respiratory system development GO:0060541 96 68 0,000 0,07698062 0,081659 ! mRNA transport GO:0051028 88 69 0,000 0,07806932 0,08278979 ! fatty acid biosynthetic process GO:0006633 76 69 0,000 0,07806932 0,08276573 ! small GTPase binding GO:0031267 86 69 0,000 0,07806932 0,08274168 ! regulation of transmission of nerve impulse GO:0051969 87 69 0,000 0,07806932 0,08271765 ! sarcomere GO:0030017 74 69 0,000 0,07806932 0,08269363 ! exocytosis GO:0006887 76 69 0,000 0,07806932 0,08266963 ! skeletal muscle tissue development GO:0007519 75 69 0,000 0,07806932 0,08264564 GO:0060538|skeletal muscle organ development, ! nucleosome assembly GO:0006334 87 69 0,000 0,07806932 0,08262166 ! extracellular ligand-gated ion channel activity GO:0005230 82 69 0,000 0,07806932 0,0825977 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 79 69 0,000 0,07806932 0,08257375 ! amine biosynthetic process GO:0009309 78 70 0,000 0,07915679 0,08369971 ! thiolester hydrolase activity GO:0016790 84 70 0,000 0,07915679 0,08367545 ! early endosome GO:0005769 104 70 0,000 0,07915679 0,08365121 ! regulation of cyclase activity GO:0031279 83 70 0,000 0,07915679 0,08362699 ! regulation of lipase activity GO:0060191 78 70 0,000 0,07915679 0,08360277 ! amino acid transport GO:0006865 76 70 0,000 0,07915679 0,08357858 ! chromatin assembly GO:0031497 88 70 0,000 0,07915679 0,08355439 ! calcium channel activity GO:0005262 86 70 0,000 0,07915679 0,08353022 ! axon guidance GO:0007411 87 70 0,000 0,07915679 0,08350607 ! nuclear chromosome part GO:0044454 94 70 0,000 0,07915679 0,08348193 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 73 71 0,000 0,08024304 0,08460307 ! mitochondrial outer membrane GO:0005741 81 71 0,000 0,08024304 0,08457862 ! protein localization in nucleus GO:0034504 78 71 0,000 0,08024304 0,08455419 ! lipoprotein metabolic process GO:0042157 76 71 0,000 0,08024304 0,08452978 ! pore complex GO:0046930 89 72 0,000 0,08132807 0,08564804 ! response to hypoxia GO:0001666 84 72 0,000 0,08132807 0,08562332 ! steroid biosynthetic process GO:0006694 83 72 0,000 0,08132807 0,08559861 ! regulation of MAPKKK cascade GO:0043408 82 72 0,000 0,08132807 0,08557392 ! regulation of lyase activity GO:0051339 85 72 0,000 0,08132807 0,08554925 ! acute inflammatory response GO:0002526 91 72 0,000 0,08132807 0,08552459 ! apical junction complex GO:0043296 90 72 0,000 0,08132807 0,08549994 ! phospholipase activity GO:0004620 99 72 0,000 0,08132807 0,08547531 ! membrane raft GO:0045121 81 72 0,000 0,08132807 0,08545069 ! regulation of neurological system process GO:0031644 91 72 0,000 0,08132807 0,08542609 ! structural constituent of cytoskeleton GO:0005200 78 72 0,000 0,08132807 0,0854015 ! elevation of cytosolic calcium ion concentration GO:0007204 87 73 0,000 0,08241187 0,08651468 GO:0051480|cytosolic calcium ion homeostasis, ! response to drug GO:0042493 94 73 0,000 0,08241187 0,08648979 ! protein transporter activity GO:0008565 80 73 0,000 0,08241187 0,08646492 ! regulation of cAMP biosynthetic process GO:0030817 86 73 0,000 0,08241187 0,08644006 ! exopeptidase activity GO:0008238 81 73 0,000 0,08241187 0,08641521 ! digestion GO:0007586 81 73 0,000 0,08241187 0,08639038 ! cell-matrix adhesion GO:0007160 102 74 0,000 0,08349446 0,08750008 ! response to oxygen levels GO:0070482 86 74 0,000 0,08349446 0,08747495 ! potassium channel complex GO:0034705 84 74 0,000 0,08349446 0,08744984 GO:0008076|voltage-gated potassium channel complex, ! GTPase binding GO:0051020 91 74 0,000 0,08349446 0,08742474 ! protein-DNA complex assembly GO:0065004 101 74 0,000 0,08349446 0,08739965 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 85 74 0,000 0,08349446 0,08737458 ! one-carbon metabolic process GO:0006730 84 74 0,000 0,08349446 0,08734952 ! blood coagulation GO:0007596 90 74 0,000 0,08349446 0,08732448 GO:0050817|coagulation, ! reproductive structure development GO:0048608 89 74 0,000 0,08349446 0,08729945 ! apicolateral plasma membrane GO:0016327 92 74 0,000 0,08349446 0,08727444 ! phosphoinositide-mediated signaling GO:0048015 92 74 0,000 0,08349446 0,08724944 ! cellular lipid catabolic process GO:0044242 99 74 0,000 0,08349446 0,08722445 ! cell projection part GO:0044463 80 74 0,000 0,08349446 0,08719948 ! meiosis GO:0007126 108 75 0,000 0,08457582 0,08830355 GO:0051327|M phase of meiotic cell cycle, ! regulation of DNA binding GO:0051101 94 75 0,000 0,08457582 0,08827828 ! carboxylic acid transmembrane transporter activity GO:0046943 85 75 0,000 0,08457582 0,08825303 ! regulation of cAMP metabolic process GO:0030814 88 75 0,000 0,08457582 0,08822779 ! regulation of blood pressure GO:0008217 82 75 0,000 0,08457582 0,08820257 ! transcription initiation GO:0006352 84 75 0,000 0,08457582 0,08817736 ! Ras GTPase activator activity GO:0005099 83 75 0,000 0,08457582 0,08815217 ! neuropeptide signaling pathway GO:0007218 85 76 0,000 0,08565597 0,08925249 ! defense response to bacterium GO:0042742 81 76 0,000 0,08565597 0,08922701 ! meiotic cell cycle GO:0051321 109 76 0,000 0,08565597 0,08920153 ! regulation of neuron differentiation GO:0045664 96 76 0,000 0,08565597 0,08917608 ! protein-DNA complex GO:0032993 93 76 0,000 0,08565597 0,08915063 ! organic acid transmembrane transporter activity GO:0005342 86 76 0,000 0,08565597 0,08912521 ! development of primary sexual characteristics GO:0045137 86 76 0,000 0,08565597 0,08909979 ! cytosolic ribosome GO:0022626 82 76 0,000 0,08565597 0,08907439 ! serine-type endopeptidase inhibitor activity GO:0004867 93 76 0,000 0,08565597 0,08904901 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 84 77 0,000 0,0867349 0,09014499 ! nucleosome organization GO:0034728 96 77 0,000 0,0867349 0,09011931 ! alcohol catabolic process GO:0046164 84 77 0,000 0,0867349 0,09009365 ! vacuolar membrane GO:0005774 86 77 0,000 0,0867349 0,09006801 ! G-protein-coupled receptor binding GO:0001664 87 77 0,000 0,0867349 0,09004238 ! myofibril GO:0030016 82 77 0,000 0,0867349 0,09001676 ! protein oligomerization GO:0051259 93 77 0,000 0,0867349 0,08999116 ! phosphoric diester hydrolase activity GO:0008081 99 78 0,000 0,08781261 0,09108343 ! endonuclease activity GO:0004519 111 78 0,000 0,08781261 0,09105754 ! cofactor biosynthetic process GO:0051188 93 78 0,000 0,08781261 0,09103166 ! inorganic anion transport GO:0015698 87 78 0,000 0,08781261 0,0910058 ! regulation of protein transport GO:0051223 85 78 0,000 0,08781261 0,09097995 ! regulation of nucleotide biosynthetic process GO:0030808 91 78 0,000 0,08781261 0,09095412 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! transmembrane receptor protein kinase activity GO:0019199 95 78 0,000 0,08781261 0,0909283 ! carboxylesterase activity GO:0004091 93 78 0,000 0,08781261 0,0909025 ! protein ubiquitination GO:0016567 95 78 0,000 0,08781261 0,09087671 ! extracellular matrix structural constituent GO:0005201 96 78 0,000 0,08781261 0,09085094 ! contractile fiber part GO:0044449 83 78 0,000 0,08781261 0,09082518 ! positive regulation of MAP kinase activity GO:0043406 89 79 0,000 0,08888911 0,09191255 ! vitamin metabolic process GO:0006766 86 79 0,000 0,08888911 0,09188651 ! T cell activation GO:0042110 120 79 0,000 0,08888911 0,09186048 ! cellular response to hormone stimulus GO:0032870 94 79 0,000 0,08888911 0,09183446 ! phosphoinositide binding GO:0035091 99 79 0,000 0,08888911 0,09180846 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 88 80 0,000 0,0899644 0,09289276 ! eye development GO:0001654 93 80 0,000 0,0899644 0,09286648 ! ATP biosynthetic process GO:0006754 89 80 0,000 0,0899644 0,09284021 ! rhythmic process GO:0048511 90 80 0,000 0,0899644 0,09281395 ! SH3 domain binding GO:0017124 95 80 0,000 0,0899644 0,09278771 ! hemostasis GO:0007599 96 80 0,000 0,0899644 0,09276149 ! regulation of cyclic nucleotide metabolic process GO:0030799 93 80 0,000 0,0899644 0,09273527 ! cell-substrate adhesion GO:0031589 109 80 0,000 0,0899644 0,09270908 ! rRNA processing GO:0006364 84 80 0,000 0,0899644 0,0926829 ! cholesterol metabolic process GO:0008203 91 81 0,000 0,09103848 0,09376295 ! vacuolar part GO:0044437 91 81 0,000 0,09103848 0,09373648 ! ossification GO:0001503 111 82 0,000 0,09211134 0,09481439 ! mitochondrion organization GO:0007005 104 82 0,000 0,09211134 0,09478764 ! biogenic amine metabolic process GO:0006576 99 82 0,000 0,09211134 0,09476091 ! forebrain development GO:0030900 93 82 0,000 0,09211134 0,09473419 ! external side of plasma membrane GO:0009897 105 82 0,000 0,09211134 0,09470749 ! cellular respiration GO:0045333 85 82 0,000 0,09211134 0,09468081 ! heparin binding GO:0008201 108 82 0,000 0,09211134 0,09465414 ! microtubule-based movement GO:0007018 119 83 0,000 0,093183 0,09572841 ! nuclear speck GO:0016607 99 83 0,000 0,093183 0,09570146 ! rRNA metabolic process GO:0016072 88 83 0,000 0,093183 0,09567452 ! ATP-dependent helicase activity GO:0008026 107 83 0,000 0,093183 0,0956476 GO:0070035|purine NTP-dependent helicase activity, ! regulation of T cell activation GO:0050863 104 83 0,000 0,093183 0,0956207 ! regulation of establishment of protein localization GO:0070201 90 83 0,000 0,093183 0,09559381 ! oxidative phosphorylation GO:0006119 85 83 0,000 0,093183 0,09556693 ! contractile fiber GO:0043292 88 83 0,000 0,093183 0,09554008 ! bone development GO:0060348 112 83 0,000 0,093183 0,09551323 ! regulation of nucleotide metabolic process GO:0006140 96 83 0,000 0,093183 0,0954864 ! regulation of membrane potential GO:0042391 98 83 0,000 0,093183 0,09545959 ! cilium GO:0005929 88 83 0,000 0,093183 0,09543279 ! regulation of defense response GO:0031347 98 84 0,000 0,09425345 0,09650199 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 94 84 0,000 0,09425345 0,09647491 ! nitrogen compound catabolic process GO:0044270 91 84 0,000 0,09425345 0,09644785 ! phospholipid biosynthetic process GO:0008654 101 85 0,000 0,09532269 0,09751464 ! protein modification by small protein conjugation GO:0032446 103 85 0,000 0,09532269 0,0974873 ! monooxygenase activity GO:0004497 92 85 0,000 0,09532269 0,09745997 ! hydrogen ion transmembrane transporter activity GO:0015078 88 85 0,000 0,09532269 0,09743267 ! protein binding, bridging GO:0030674 104 85 0,000 0,09532269 0,09740538 ! negative regulation of transport GO:0051051 98 86 0,000 0,09639073 0,09846917 ! clathrin-coated vesicle GO:0030136 100 86 0,000 0,09639073 0,0984416 ! Golgi vesicle transport GO:0048193 98 86 0,000 0,09639073 0,09841405 ! lipase activity GO:0016298 114 86 0,000 0,09639073 0,09838651 ! voltage-gated potassium channel activity GO:0005249 105 86 0,000 0,09639073 0,09835899 ! adherens junction GO:0005912 100 86 0,000 0,09639073 0,09833149 ! leukocyte differentiation GO:0002521 118 87 0,000 0,09745757 0,09939201 ! regulation of cell morphogenesis GO:0022604 100 87 0,000 0,09745757 0,09936423 ! organelle outer membrane GO:0031968 102 88 0,000 0,0985232 0,10042264 ! carbohydrate biosynthetic process GO:0016051 95 88 0,000 0,0985232 0,10039459 ! growth factor binding GO:0019838 102 88 0,000 0,0985232 0,10036656 ! protein processing GO:0016485 100 88 0,000 0,0985232 0,10033854 ! gland development GO:0048732 108 89 0,000 0,09958763 0,10139427 ! ATP metabolic process GO:0046034 100 90 0,000 0,10065086 0,1024482 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 101 90 0,000 0,10065086 0,10241962 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! peroxisome GO:0005777 100 90 0,000 0,10065086 0,10239106 GO:0042579|microbody, ! glycerophospholipid metabolic process GO:0006650 109 90 0,000 0,10065086 0,10236252 ! sterol metabolic process GO:0016125 102 90 0,000 0,10065086 0,10233399 ! negative regulation of multicellular organismal process GO:0051241 102 90 0,000 0,10065086 0,10230548 ! anion binding GO:0043168 104 90 0,000 0,10065086 0,10227698 ! amine transport GO:0015837 97 90 0,000 0,10065086 0,1022485 ! response to virus GO:0009615 109 90 0,000 0,10065086 0,10222003 ! outer membrane GO:0019867 104 90 0,000 0,10065086 0,10219158 ! extracellular matrix part GO:0044420 111 90 0,000 0,10065086 0,10216315 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 108 91 0,000 0,1017129 0,10321242 ! ribonucleoside triphosphate biosynthetic process GO:0009201 102 91 0,000 0,1017129 0,10318372 GO:0009142|nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 104 91 0,000 0,1017129 0,10315503 ! sulfur metabolic process GO:0006790 98 91 0,000 0,1017129 0,10312636 ! sex differentiation GO:0007548 103 91 0,000 0,1017129 0,10309771 ! hormone metabolic process GO:0042445 107 91 0,000 0,1017129 0,10306907 ! regulation of protein localization GO:0032880 99 91 0,000 0,1017129 0,10304045 ! detection of stimulus GO:0051606 100 91 0,000 0,1017129 0,10301184 ! structure-specific DNA binding GO:0043566 112 92 0,000 0,10277373 0,10405734 ! anatomical structure homeostasis GO:0060249 121 92 0,000 0,10277373 0,10402846 ! carboxylic acid catabolic process GO:0046395 100 92 0,000 0,10277373 0,10399961 GO:0016054|organic acid catabolic process, ! translation factor activity, nucleic acid binding GO:0008135 108 92 0,000 0,10277373 0,10397077 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 111 92 0,000 0,10277373 0,10394194 ! extracellular structure organization GO:0043062 119 92 0,000 0,10277373 0,10391313 ! protein import GO:0017038 102 93 0,000 0,10383337 0,10495543 ! neurotransmitter receptor activity GO:0030594 104 93 0,000 0,10383337 0,10492636 ! response to nutrient levels GO:0031667 105 93 0,000 0,10383337 0,1048973 ! Ras protein signal transduction GO:0007265 118 93 0,000 0,10383337 0,10486826 ! protein modification by small protein conjugation or removal GO:0070647 112 93 0,000 0,10383337 0,10483923 ! ATPase activity, coupled to transmembrane movement of substances GO:0042626 102 94 0,000 0,10489182 0,10587863 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 104 94 0,000 0,10489182 0,10584934 ! morphogenesis of an epithelium GO:0002009 113 94 0,000 0,10489182 0,10582007 GO:0060429|epithelium development, ! anchoring junction GO:0070161 108 94 0,000 0,10489182 0,10579081 ! neurotransmitter binding GO:0042165 105 94 0,000 0,10489182 0,10576157 ! DNA packaging GO:0006323 113 94 0,000 0,10489182 0,10573235 ! homophilic cell adhesion GO:0007156 107 95 0,000 0,10594907 0,10676857 ! ATPase activity, coupled to movement of substances GO:0043492 104 95 0,000 0,10594907 0,10673908 ! anterior/posterior pattern formation GO:0009952 109 95 0,000 0,10594907 0,10670961 ! protein localization in organelle GO:0033365 104 95 0,000 0,10594907 0,10668016 ! Wnt receptor signaling pathway GO:0016055 121 95 0,000 0,10594907 0,10665072 ! immune effector process GO:0002252 110 95 0,000 0,10594907 0,1066213 ! apical plasma membrane GO:0016324 105 95 0,000 0,10594907 0,1065919 ! translational elongation GO:0006414 104 96 0,000 0,10700513 0,10762468 ! hydrolase activity, acting on glycosyl bonds GO:0016798 109 96 0,000 0,10700513 0,10759502 ! in utero embryonic development GO:0001701 110 96 0,000 0,10700513 0,10756537 ! carbohydrate catabolic process GO:0016052 116 96 0,000 0,10700513 0,10753574 ! receptor complex GO:0043235 131 96 0,000 0,10700513 0,10750612 ! regulation of response to external stimulus GO:0032101 109 96 0,000 0,10700513 0,10747652 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 100 96 0,000 0,10700513 0,10744694 ! electron transport chain GO:0022900 104 97 0,000 0,10806 0,1084763 ! microtubule associated complex GO:0005875 135 97 0,000 0,10806 0,10844646 ! metalloendopeptidase activity GO:0004222 126 97 0,000 0,10806 0,10841663 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances GO:0016820 105 97 0,000 0,10806 0,10838683 ! carboxylic acid binding GO:0031406 108 97 0,000 0,10806 0,10835703 ! protein maturation GO:0051604 109 97 0,000 0,10806 0,10832726 ! intermediate filament GO:0005882 102 98 0,000 0,10911368 0,10935349 GO:0045111|intermediate filament cytoskeleton, ! UDP-glycosyltransferase activity GO:0008194 120 98 0,000 0,10911368 0,10932346 ! cell fate commitment GO:0045165 118 98 0,000 0,10911368 0,10929344 ! hormone activity GO:0005179 113 99 0,000 0,11016617 0,11031738 ! solute:cation symporter activity GO:0015294 110 99 0,000 0,11016617 0,1102871 ! nuclear chromosome GO:0000228 127 100 0,000 0,11121748 0,11130901 ! regulation of neurogenesis GO:0050767 123 100 0,000 0,11121748 0,11127849 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016810 105 100 0,000 0,11121748 0,11124797 ! peptide receptor activity, G-protein coupled GO:0008528 107 100 0,000 0,11121748 0,11121748