pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/2671-3-real-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 156 86 4,000 3,313E-07 7,62E-04 ! interphase GO:0051325 159 88 4,000 3,718E-07 4,276E-04 ! induction of apoptosis by intracellular signals GO:0008629 67 40 3,000 6,167E-07 4,728E-04 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 3,000 8,299E-07 4,772E-04 ! negative regulation of caspase activity GO:0043154 20 14 2,000 1,639E-06 7,539E-04 ! axon cargo transport GO:0008088 27 14 2,000 1,639E-06 6,282E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 1,665E-06 5,469E-04 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 2,612E-06 7,51E-04 ! negative regulation of kinase activity GO:0033673 100 58 3,000 2,802E-06 7,162E-04 ! negative regulation of peptidase activity GO:0010466 23 17 2,000 3,051E-06 7,017E-04 ! negative regulation of transferase activity GO:0051348 105 61 3,000 3,435E-06 7,182E-04 ! microtubule-based transport GO:0010970 37 20 2,000 5,097E-06 9,77E-04 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 2,000 5,94E-06 1,051E-03 ! negative regulation of hydrolase activity GO:0051346 50 33 2,000 2,403E-05 3,948E-03 ! positive regulation of viral genome replication GO:0045070 8 5 1,000 2,838E-05 4,351E-03 ! regulation of retroviral genome replication GO:0045091 6 5 1,000 2,838E-05 4,079E-03 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 1,000 4,252E-05 5,753E-03 ! spindle checkpoint GO:0031577 14 6 1,000 4,252E-05 5,433E-03 ! DNA topological change GO:0006265 8 6 1,000 4,252E-05 5,147E-03 ! establishment of chromosome localization GO:0051303 9 6 1,000 4,252E-05 4,89E-03 GO:0050000|chromosome localization, ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 2,000 4,316E-05 4,727E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 5,947E-05 6,217E-03 ! positive regulation of mitotic cell cycle GO:0045931 11 7 1,000 5,947E-05 5,947E-03 ! positive regulation of cell cycle GO:0045787 77 45 2,000 6,164E-05 5,907E-03 ! response to UV GO:0009411 75 46 2,000 6,586E-05 6,059E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 7,92E-05 7,006E-03 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 7,92E-05 6,747E-03 ! keratinocyte proliferation GO:0043616 12 8 1,000 7,92E-05 6,506E-03 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 1,000 7,92E-05 6,282E-03 ! regulation of exit from mitosis GO:0007096 12 9 1,000 1,017E-04 7,799E-03 ! DNA ligation GO:0006266 14 9 1,000 1,017E-04 7,547E-03 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,27E-04 9,129E-03 ! positive regulation of viral reproduction GO:0048524 15 10 1,000 1,27E-04 8,853E-03 ! regulation of caspase activity GO:0043281 97 65 2,000 1,854E-04 0,01254087 ! positive regulation of cell growth GO:0030307 16 12 1,000 1,859E-04 0,01221595 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 2,028E-04 0,01295978 ! regulation of peptidase activity GO:0052547 106 72 2,000 2,511E-04 0,01560786 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 2,558E-04 0,01548039 ! positive regulation of cell size GO:0045793 20 15 1,000 2,948E-04 0,01738543 ! skin development GO:0043588 25 15 1,000 2,948E-04 0,01695079 ! cellular response to unfolded protein GO:0034620 19 16 1,000 3,366E-04 0,01887968 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of viral genome replication GO:0045069 24 17 1,000 3,81E-04 0,02086524 ! inactivation of MAPK activity GO:0000188 27 17 1,000 3,81E-04 0,02038 ! cell cycle arrest GO:0007050 150 86 2,000 4,239E-04 0,02215999 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 4,282E-04 0,02188514 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 4,781E-04 0,02390261 ! apoptotic nuclear changes GO:0030262 24 19 1,000 4,781E-04 0,02339404 ! chromosome condensation GO:0030261 31 20 1,000 5,306E-04 0,02542471 ! positive regulation of B cell activation GO:0050871 31 20 1,000 5,306E-04 0,02490584 ! response to light stimulus GO:0009416 153 96 2,000 5,851E-04 0,02691277 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 5,858E-04 0,0264198 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 5,858E-04 0,02591173 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 6,437E-04 0,0279353 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 7,043E-04 0,02999721 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 7,043E-04 0,0294518 ! regulation of viral reproduction GO:0050792 32 23 1,000 7,043E-04 0,02892588 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 7,043E-04 0,02841841 ! fat cell differentiation GO:0045444 37 24 1,000 7,675E-04 0,03043491 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 8,333E-04 0,03248606 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of nuclear division GO:0051785 39 25 1,000 8,333E-04 0,03194463 GO:0045840|positive regulation of mitosis, ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 1,047E-03 0,03946397 ! regulation of B cell activation GO:0050864 42 28 1,000 1,047E-03 0,03882745 ! nucleus organization GO:0006997 49 33 1,000 1,454E-03 0,05309064 ! cytokinesis GO:0000910 52 33 1,000 1,454E-03 0,0522611 ! keratinocyte differentiation GO:0030216 47 35 1,000 1,635E-03 0,05786325 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 1,635E-03 0,05698654 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! JNK cascade GO:0007254 54 39 1,000 2,028E-03 0,06961333 ! response to calcium ion GO:0051592 58 40 1,000 2,132E-03 0,07212275 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 1,000 2,132E-03 0,07107749 ! epidermal cell differentiation GO:0009913 53 40 1,000 2,132E-03 0,0700621 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 2,575E-03 0,08341996 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 1,000 2,933E-03 0,09370091 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 2,933E-03 0,09241734 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! RNA elongation GO:0006354 62 49 1,000 3,184E-03 0,09896965 ! positive regulation of growth GO:0045927 67 50 1,000 3,313E-03 0,10161066 ! positive regulation of organelle organization GO:0010638 82 51 1,000 3,445E-03 0,10425552 ! establishment of organelle localization GO:0051656 85 52 1,000 3,579E-03 0,10690384 ! regulation of mitosis GO:0007088 84 54 1,000 3,854E-03 0,113648 GO:0051783|regulation of nuclear division, ! DNA damage response, signal transduction GO:0042770 96 56 1,000 4,139E-03 0,12049995 ! chromosome segregation GO:0007059 83 57 1,000 4,285E-03 0,1231897 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 4,892E-03 0,13891564 ! negative regulation of cell growth GO:0030308 106 62 1,000 5,05E-03 0,141645 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 5,05E-03 0,13993844 ! organelle localization GO:0051640 96 62 1,000 5,05E-03 0,1382725 ! negative regulation of cell size GO:0045792 108 64 1,000 5,372E-03 0,14536917 ! cell cycle checkpoint GO:0000075 108 64 1,000 5,372E-03 0,14367883 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 5,372E-03 0,14202735 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 5,537E-03 0,14471715 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 5,537E-03 0,14309112 ! positive regulation of ligase activity GO:0051351 99 69 1,000 6,219E-03 0,15892046 ! response to metal ion GO:0010038 103 70 1,000 6,395E-03 0,16162514 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 6,395E-03 0,15986834 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 1,000 6,395E-03 0,15814933 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 6,573E-03 0,16083131 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 6,573E-03 0,15913835 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 6,754E-03 0,16180823 GO:0045937|positive regulation of phosphate metabolic process, ! mitochondrion organization GO:0007005 104 73 1,000 6,937E-03 0,16447641 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 7,122E-03 0,16714274 ! response to inorganic substance GO:0010035 115 75 1,000 7,309E-03 0,16980711 ! negative regulation of growth GO:0045926 123 75 1,000 7,309E-03 0,16810904 ! regulation of ligase activity GO:0051340 114 75 1,000 7,309E-03 0,16644459 ! response to unfolded protein GO:0006986 99 76 1,000 7,499E-03 0,16908765 ! protein ubiquitination GO:0016567 125 77 1,000 7,69E-03 0,17172892 ! positive regulation of protein modification process GO:0031401 107 78 1,000 7,884E-03 0,1743683 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 8,279E-03 0,1813518 GO:0010498|proteasomal protein catabolic process, ! regulation of cell cycle process GO:0010564 122 81 1,000 8,48E-03 0,18399353 ! response to protein stimulus GO:0051789 111 81 1,000 8,48E-03 0,18227397 ! positive regulation of cell activation GO:0050867 120 81 1,000 8,48E-03 0,18058625 GO:0002696|positive regulation of leukocyte activation, ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 8,552E-03 0,18045148 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 8,552E-03 0,17881102 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 8,552E-03 0,17720011 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 8,552E-03 0,17561796 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 8,552E-03 0,17406382 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 8,552E-03 0,17253695 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 8,552E-03 0,17103662 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 8,552E-03 0,16956217 ! sleep GO:0030431 11 5 0,000 8,552E-03 0,16811292 ! negative regulation of bone resorption GO:0045779 10 5 0,000 8,552E-03 0,16668824 ! nucleotide-sugar transport GO:0015780 8 5 0,000 8,552E-03 0,16528749 ! regulation of interferon-beta production GO:0032648 5 5 0,000 8,552E-03 0,1639101 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 8,552E-03 0,16255547 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 8,552E-03 0,16122305 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 8,552E-03 0,15991229 ! tongue development GO:0043586 6 5 0,000 8,552E-03 0,15862268 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 8,552E-03 0,15735369 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 8,552E-03 0,15610486 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 8,552E-03 0,15487568 ! cobalt ion transport GO:0006824 9 5 0,000 8,552E-03 0,15366572 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 8,552E-03 0,15247451 ! SMAD protein complex assembly GO:0007183 9 5 0,000 8,552E-03 0,15130163 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 8,552E-03 0,15014666 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 8,552E-03 0,14900918 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 8,552E-03 0,14788881 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 8,552E-03 0,14678516 ! embryonic camera-type eye development GO:0031076 8 5 0,000 8,552E-03 0,14569787 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 8,552E-03 0,14462656 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 8,552E-03 0,14357089 ! adaptation of signaling pathway GO:0022401 7 5 0,000 8,552E-03 0,14253052 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 8,552E-03 0,14150512 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 8,552E-03 0,14049437 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 8,552E-03 0,13949796 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 8,552E-03 0,13851558 ! positive regulation of histone modification GO:0031058 5 5 0,000 8,552E-03 0,13754694 ! malate metabolic process GO:0006108 7 5 0,000 8,552E-03 0,13659175 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 8,552E-03 0,13564974 ! behavioral response to pain GO:0048266 7 5 0,000 8,552E-03 0,13472063 ! clathrin coat assembly GO:0048268 11 5 0,000 8,552E-03 0,13380416 ! phototransduction, visible light GO:0007603 6 5 0,000 8,552E-03 0,13290008 ! regulation of dopamine uptake GO:0051584 9 5 0,000 8,552E-03 0,13200813 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 8,552E-03 0,13112808 ! mating behavior GO:0007617 6 5 0,000 8,552E-03 0,13025968 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 8,552E-03 0,12940271 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 8,552E-03 0,12855694 ! rhythmic behavior GO:0007622 12 5 0,000 8,552E-03 0,12772215 ! copulation GO:0007620 7 5 0,000 8,552E-03 0,12689814 ! glial cell fate commitment GO:0021781 12 5 0,000 8,552E-03 0,12608469 ! protein maturation by protein folding GO:0022417 12 5 0,000 8,552E-03 0,1252816 ! embryonic hemopoiesis GO:0035162 10 5 0,000 8,552E-03 0,12448868 ! regulation of potassium ion transport GO:0043266 9 5 0,000 8,552E-03 0,12370573 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 8,552E-03 0,12293257 ! apoptotic cell clearance GO:0043277 13 5 0,000 8,552E-03 0,12216902 ! lipoprotein particle clearance GO:0034381 9 5 0,000 8,552E-03 0,12141489 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 8,552E-03 0,12067001 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 8,552E-03 0,11993422 ! response to protozoan GO:0001562 9 5 0,000 8,552E-03 0,11920734 ! positive regulation of glycolysis GO:0045821 11 5 0,000 8,552E-03 0,11848923 ! lymph vessel development GO:0001945 7 5 0,000 8,552E-03 0,11777971 ! endochondral ossification GO:0001958 12 5 0,000 8,552E-03 0,11707864 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 8,552E-03 0,11638587 ! parathyroid gland development GO:0060017 8 5 0,000 8,552E-03 0,11570125 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 8,552E-03 0,11502463 ! anagen GO:0042640 6 5 0,000 8,552E-03 0,11435588 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 8,552E-03 0,11369487 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 8,552E-03 0,11304145 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 8,552E-03 0,1123955 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 8,552E-03 0,11175689 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 8,552E-03 0,11112549 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 8,552E-03 0,11050119 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 8,552E-03 0,10988386 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 8,552E-03 0,1092734 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 8,552E-03 0,10866968 ! cardiac muscle fiber development GO:0048739 7 5 0,000 8,552E-03 0,10807259 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 8,552E-03 0,10748203 ! neutrophil mediated immunity GO:0002446 6 5 0,000 8,552E-03 0,10689789 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 8,552E-03 0,10632006 ! ovulation GO:0030728 6 5 0,000 8,552E-03 0,10574845 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 8,552E-03 0,10518295 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 8,552E-03 0,10462347 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 8,552E-03 0,1040699 ! response to pH GO:0009268 9 5 0,000 8,552E-03 0,10352217 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 8,552E-03 0,10298017 ! proline biosynthetic process GO:0006561 6 5 0,000 8,552E-03 0,10244381 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 8,552E-03 0,10191301 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 8,552E-03 0,10138769 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 8,552E-03 0,10086775 ! polyol catabolic process GO:0046174 7 5 0,000 8,552E-03 0,10035312 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 8,552E-03 0,09984371 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 8,552E-03 0,09933945 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 8,552E-03 0,09884026 ! sister chromatid cohesion GO:0007062 9 5 0,000 8,552E-03 0,09834606 ! nerve growth factor processing GO:0032455 7 5 0,000 8,552E-03 0,09785678 ! urea metabolic process GO:0019627 6 5 0,000 8,552E-03 0,09737234 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 8,552E-03 0,09689267 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 8,552E-03 0,0964177 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 8,552E-03 0,09594737 ! neutrophil activation GO:0042119 5 5 0,000 8,552E-03 0,09548161 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 8,552E-03 0,09502035 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 8,552E-03 0,09456352 ! response to food GO:0032094 5 5 0,000 8,552E-03 0,09411106 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 8,552E-03 0,09366291 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 8,552E-03 0,09321901 ! paraxial mesoderm development GO:0048339 9 5 0,000 8,552E-03 0,0927793 ! forebrain neuron development GO:0021884 7 5 0,000 8,552E-03 0,09234372 ! melanosome organization GO:0032438 7 5 0,000 8,552E-03 0,0919122 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 8,552E-03 0,09148471 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 8,552E-03 0,09106117 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 8,552E-03 0,09064153 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 8,552E-03 0,09022574 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 8,552E-03 0,08981375 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 8,552E-03 0,08940551 ! nucleoside transport GO:0015858 6 5 0,000 8,552E-03 0,08900096 ! nucleoside salvage GO:0043174 7 5 0,000 8,552E-03 0,08860005 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 8,552E-03 0,08820274 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 8,552E-03 0,08780898 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 8,552E-03 0,08741872 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 8,552E-03 0,08703191 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 8,552E-03 0,08664851 ! early endosome to late endosome transport GO:0045022 11 5 0,000 8,552E-03 0,08626847 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 8,552E-03 0,08589175 ! depyrimidination GO:0045008 8 5 0,000 8,552E-03 0,08551831 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 8,552E-03 0,0851481 ! 5S class rRNA transcription GO:0042791 8 5 0,000 8,552E-03 0,08478109 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 8,552E-03 0,08441722 ! regulation of centrosome cycle GO:0046605 7 5 0,000 8,552E-03 0,08405646 ! neuronal ion channel clustering GO:0045161 7 5 0,000 8,552E-03 0,08369877 ! sodium ion homeostasis GO:0055078 6 5 0,000 8,552E-03 0,08334412 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 8,552E-03 0,08299245 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 8,552E-03 0,08264375 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 8,552E-03 0,08229796 ! monocyte differentiation GO:0030224 8 5 0,000 8,552E-03 0,08195505 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 8,552E-03 0,08161499 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 8,552E-03 0,08127773 ! centrosome duplication GO:0051298 5 5 0,000 8,552E-03 0,08094326 ! response to UV-C GO:0010225 6 5 0,000 8,552E-03 0,08061152 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 8,552E-03 0,0802825 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 8,552E-03 0,07995615 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 8,552E-03 0,07963244 ! regulation of dendrite development GO:0050773 12 5 0,000 8,552E-03 0,07931134 ! peptidyl-arginine modification GO:0018195 7 5 0,000 8,552E-03 0,07899282 ! positive regulation of organ growth GO:0046622 6 5 0,000 8,552E-03 0,07867685 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 8,552E-03 0,07836339 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 8,552E-03 0,07805243 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 8,552E-03 0,07774392 ! regulation of dopamine secretion GO:0014059 12 5 0,000 8,552E-03 0,07743784 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 8,552E-03 0,07713416 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 8,552E-03 0,07683286 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 8,552E-03 0,0765339 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 8,552E-03 0,07623726 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 8,552E-03 0,0759429 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 8,552E-03 0,07565081 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 8,552E-03 0,07536096 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 8,552E-03 0,07507333 ! neural tube patterning GO:0021532 6 5 0,000 8,552E-03 0,07478788 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 8,552E-03 0,07450459 ! histone demethylation GO:0016577 9 5 0,000 8,552E-03 0,07422344 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 8,552E-03 0,07394441 ! regulation of sterol transport GO:0032371 7 5 0,000 8,552E-03 0,07366746 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 8,552E-03 0,07339258 ! enteric nervous system development GO:0048484 8 5 0,000 8,552E-03 0,07311975 ! establishment of planar polarity GO:0001736 6 5 0,000 8,552E-03 0,07284893 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 8,552E-03 0,07258012 ! muscle cell proliferation GO:0033002 8 5 0,000 8,552E-03 0,07231328 ! transcription termination GO:0006353 8 5 0,000 8,552E-03 0,07204839 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 8,552E-03 0,07178544 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 8,552E-03 0,07152441 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 8,552E-03 0,07126526 ! regulation of respiratory burst GO:0060263 8 5 0,000 8,552E-03 0,07100798 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 8,552E-03 0,07075256 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 8,552E-03 0,07049897 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 8,552E-03 0,07024719 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 8,552E-03 0,0699972 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 8,552E-03 0,06974898 ! apical protein localization GO:0045176 6 5 0,000 8,552E-03 0,06950252 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 8,552E-03 0,06925779 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 8,552E-03 0,06901478 ! galactolipid metabolic process GO:0019374 7 5 0,000 8,552E-03 0,06877347 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 8,552E-03 0,06853384 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 8,552E-03 0,06829587 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 8,552E-03 0,06805956 ! triglyceride catabolic process GO:0019433 6 5 0,000 8,552E-03 0,06782487 ! glial cell migration GO:0008347 10 5 0,000 8,552E-03 0,06759179 ! determination of adult lifespan GO:0008340 8 5 0,000 8,552E-03 0,06736031 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 8,552E-03 0,06713042 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 8,552E-03 0,06690208 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 8,552E-03 0,06667529 ! somatic stem cell maintenance GO:0035019 13 5 0,000 8,552E-03 0,06645004 ! cerebellar cortex formation GO:0021697 6 5 0,000 8,552E-03 0,0662263 ! neural plate development GO:0001840 6 5 0,000 8,552E-03 0,06600407 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 8,552E-03 0,06578332 ! regulation of sensory perception GO:0051931 6 5 0,000 8,552E-03 0,06556404 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 8,552E-03 0,06534622 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 8,552E-03 0,06512984 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 8,552E-03 0,06491489 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 8,552E-03 0,06470135 ! sensory cilium assembly GO:0035058 6 5 0,000 8,552E-03 0,06448922 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 8,552E-03 0,06427847 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 8,552E-03 0,06406909 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 8,552E-03 0,06386108 ! spindle assembly GO:0051225 5 5 0,000 8,552E-03 0,06365441 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 8,552E-03 0,06344907 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 8,552E-03 0,06324505 ! protein amino acid prenylation GO:0018346 9 5 0,000 8,552E-03 0,06304235 ! organ regeneration GO:0031100 7 5 0,000 8,552E-03 0,06284093 ! NAD biosynthetic process GO:0009435 7 5 0,000 8,552E-03 0,0626408 ! carnitine metabolic process GO:0009437 5 5 0,000 8,552E-03 0,06244194 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 8,552E-03 0,06224434 ! cellular anion homeostasis GO:0030002 6 5 0,000 8,552E-03 0,06204799 GO:0055081|anion homeostasis, ! transcription initiation GO:0006352 118 85 1,000 9,304E-03 0,06729182 ! tRNA transcription GO:0009304 11 6 0,000 0,01025369 0,07392945 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01025369 0,07369842 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01025369 0,07346883 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01025369 0,07324067 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01025369 0,07301392 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01025369 0,07278856 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01025369 0,0725646 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01025369 0,07234201 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01025369 0,07212078 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01025369 0,0719009 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01025369 0,07168235 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01025369 0,07146514 ! prostate gland development GO:0030850 9 6 0,000 0,01025369 0,07124923 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01025369 0,07103462 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01025369 0,07082131 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01025369 0,07060927 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01025369 0,07039849 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01025369 0,07018897 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01025369 0,0699807 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01025369 0,06977365 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01025369 0,06956783 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01025369 0,06936322 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01025369 0,06915981 ! neuron adhesion GO:0007158 9 6 0,000 0,01025369 0,06895759 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01025369 0,06875654 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01025369 0,06855667 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01025369 0,06835796 ! signal peptide processing GO:0006465 8 6 0,000 0,01025369 0,06816039 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01025369 0,06796396 ! mRNA stabilization GO:0048255 15 6 0,000 0,01025369 0,06776866 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01025369 0,06757448 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01025369 0,06738141 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01025369 0,06718944 ! opsonization GO:0008228 8 6 0,000 0,01025369 0,06699856 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01025369 0,06680877 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01025369 0,06662004 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01025369 0,06643238 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01025369 0,06624577 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01025369 0,06606021 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01025369 0,06587568 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01025369 0,06569219 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01025369 0,06550971 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01025369 0,06532824 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01025369 0,06514778 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01025369 0,06496831 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01025369 0,06478982 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01025369 0,06461231 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01025369 0,06443578 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01025369 0,0642602 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01025369 0,06408558 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01025369 0,06391191 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01025369 0,06373918 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01025369 0,06356737 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01025369 0,06339649 ! thymic T cell selection GO:0045061 12 6 0,000 0,01025369 0,06322653 ! protein lipoylation GO:0009249 10 6 0,000 0,01025369 0,06305747 ! pigment granule organization GO:0048753 11 6 0,000 0,01025369 0,06288932 ! drug transport GO:0015893 6 6 0,000 0,01025369 0,06272206 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01025369 0,06255569 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01025369 0,0623902 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01025369 0,06222558 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01025369 0,06206183 ! histidine metabolic process GO:0006547 6 6 0,000 0,01025369 0,06189894 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01025369 0,0617369 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01025369 0,0615757 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01025369 0,06141535 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01025369 0,06125583 ! adenohypophysis development GO:0021984 10 6 0,000 0,01025369 0,06109714 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01025369 0,06093926 ! hyperosmotic response GO:0006972 8 6 0,000 0,01025369 0,0607822 ! microtubule nucleation GO:0007020 10 6 0,000 0,01025369 0,06062595 ! ER overload response GO:0006983 7 6 0,000 0,01025369 0,0604705 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01025369 0,06031584 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01025369 0,06016198 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01025369 0,06000889 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01025369 0,05985659 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01025369 0,05970505 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01025369 0,05955428 ! response to dietary excess GO:0002021 7 6 0,000 0,01025369 0,05940427 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01025369 0,05925501 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01025369 0,0591065 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01025369 0,05895874 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01025369 0,05881171 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01025369 0,05866541 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01025369 0,05851984 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01025369 0,05837499 ! neuron apoptosis GO:0051402 8 6 0,000 0,01025369 0,05823085 ! organic alcohol transport GO:0015850 9 6 0,000 0,01025369 0,05808743 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01025369 0,0579447 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01025369 0,05780268 ! male sex determination GO:0030238 9 6 0,000 0,01025369 0,05766136 ! carnitine transport GO:0015879 8 6 0,000 0,01025369 0,05752072 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01025369 0,05738077 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01025369 0,05724149 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01025369 0,05710289 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01025369 0,05696496 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01025369 0,0568277 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01025369 0,05669109 ! parturition GO:0007567 12 6 0,000 0,01025369 0,05655514 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01025369 0,05641984 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01025369 0,05628519 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01025369 0,05615118 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01025369 0,0560178 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01025369 0,05588506 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01025369 0,05575294 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01025369 0,05562145 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01025369 0,05549058 ! macrophage differentiation GO:0030225 10 6 0,000 0,01025369 0,05536032 ! astrocyte development GO:0014002 14 6 0,000 0,01025369 0,05523067 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01025369 0,05510162 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01025369 0,05497318 ! interaction with symbiont GO:0051702 8 6 0,000 0,01025369 0,05484534 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01025369 0,05471809 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01025369 0,05459142 ! eating behavior GO:0042755 6 6 0,000 0,01025369 0,05446535 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01025369 0,05433985 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01025369 0,05421493 ! response to copper ion GO:0046688 9 6 0,000 0,01025369 0,05409058 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01025369 0,05396681 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01025369 0,0538436 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01025369 0,05372094 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01025369 0,05359885 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01025369 0,05347731 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01025369 0,05335632 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01025369 0,05323588 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01025369 0,05311598 ! gas homeostasis GO:0033483 11 6 0,000 0,01025369 0,05299662 ! hair follicle maturation GO:0048820 7 6 0,000 0,01025369 0,05287779 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01025369 0,0527595 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01025369 0,05264173 ! Schwann cell development GO:0014044 14 6 0,000 0,01025369 0,05252449 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01025369 0,05240777 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01025369 0,05229156 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01025369 0,05217587 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01025369 0,05206069 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01025369 0,05194602 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01025369 0,05183186 ! histone ubiquitination GO:0016574 7 6 0,000 0,01025369 0,05171819 ! regulation of meiosis GO:0040020 10 6 0,000 0,01025369 0,05160502 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01025369 0,05149235 GO:0000085|G2 phase of mitotic cell cycle, ! regulation of cell division GO:0051302 8 6 0,000 0,01025369 0,05138016 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01025369 0,05126847 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01025369 0,05115726 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01025369 0,05104653 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01025369 0,05093627 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01025369 0,0508265 ! receptor internalization GO:0031623 9 6 0,000 0,01025369 0,05071719 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01025369 0,05060836 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01025369 0,05049999 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01025369 0,05039208 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01025369 0,05028464 ! protein deubiquitination GO:0016579 8 6 0,000 0,01025369 0,05017765 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01025369 0,05007111 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01025369 0,04996503 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01025369 0,0498594 ! axonal fasciculation GO:0007413 9 6 0,000 0,01025369 0,04975421 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01025369 0,04964946 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01025369 0,04954516 ! midbrain development GO:0030901 6 6 0,000 0,01025369 0,04944129 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01025369 0,04933786 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01025369 0,04923485 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01025369 0,04913228 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01025369 0,04903013 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01025369 0,04892841 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01025369 0,04882711 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01025369 0,04872623 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01025369 0,04862576 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01025369 0,04852571 ! adult feeding behavior GO:0008343 6 6 0,000 0,01025369 0,04842607 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01025369 0,04832683 ! blastocyst growth GO:0001832 15 6 0,000 0,01025369 0,04822801 ! pigment granule transport GO:0051904 12 6 0,000 0,01025369 0,04812958 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01025369 0,04803156 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01025369 0,04793393 ! catecholamine transport GO:0051937 7 6 0,000 0,01025369 0,0478367 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01025369 0,04773987 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01025369 0,04764342 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01025369 0,04754737 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01025369 0,0474517 ! protein prenylation GO:0018342 10 6 0,000 0,01025369 0,04735642 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01025369 0,04726151 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01025369 0,04716699 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01025369 0,04707284 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01025369 0,04697907 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01025369 0,04688568 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,01038231 0,0473796 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,01174615 0,05349734 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,01174615 0,05339161 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01195273 0,05422344 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01195273 0,0541167 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01195273 0,05401038 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01195273 0,05390448 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01195273 0,05379899 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01195273 0,05369391 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01195273 0,05358924 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01195273 0,05348499 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01195273 0,05338113 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01195273 0,05327768 ! reproductive behavior GO:0019098 12 7 0,000 0,01195273 0,05317463 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01195273 0,05307197 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01195273 0,05296972 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01195273 0,05286785 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01195273 0,05276638 ! oligopeptide transport GO:0006857 11 7 0,000 0,01195273 0,05266529 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01195273 0,05256459 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01195273 0,05246428 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,01195273 0,05236435 ! RNA methylation GO:0001510 11 7 0,000 0,01195273 0,0522648 ! pericardium development GO:0060039 8 7 0,000 0,01195273 0,05216562 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01195273 0,05206682 ! fibril organization GO:0043206 13 7 0,000 0,01195273 0,0519684 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01195273 0,05187034 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01195273 0,05177266 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01195273 0,05167534 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01195273 0,05157839 ! lipoprotein transport GO:0042953 9 7 0,000 0,01195273 0,0514818 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01195273 0,05138557 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01195273 0,05128971 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01195273 0,05119419 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01195273 0,05109904 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01195273 0,05100423 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01195273 0,05090978 ! chemosensory behavior GO:0007635 9 7 0,000 0,01195273 0,05081568 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01195273 0,05072192 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01195273 0,05062851 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01195273 0,05053545 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01195273 0,05044272 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01195273 0,05035033 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01195273 0,05025829 ! reflex GO:0060004 12 7 0,000 0,01195273 0,05016657 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01195273 0,0500752 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01195273 0,04998415 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01195273 0,04989343 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01195273 0,04980305 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01195273 0,04971299 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01195273 0,04962325 ! spinal cord patterning GO:0021511 7 7 0,000 0,01195273 0,04953384 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01195273 0,04944475 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01195273 0,04935598 ! adrenal gland development GO:0030325 17 7 0,000 0,01195273 0,04926753 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01195273 0,0491794 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01195273 0,04909158 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01195273 0,04900407 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01195273 0,04891687 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01195273 0,04882999 ! endosome organization GO:0007032 10 7 0,000 0,01195273 0,04874341 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01195273 0,04865714 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01195273 0,04857117 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01195273 0,04848551 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01195273 0,04840014 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01195273 0,04831508 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01195273 0,04823032 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01195273 0,04814585 ! galactose metabolic process GO:0006012 10 7 0,000 0,01195273 0,04806168 ! vesicle fusion GO:0006906 15 7 0,000 0,01195273 0,04797781 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01195273 0,04789422 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01195273 0,04781093 ! organ growth GO:0035265 11 7 0,000 0,01195273 0,04772792 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01195273 0,0476452 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01195273 0,04756277 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01195273 0,04748063 ! retinol metabolic process GO:0042572 9 7 0,000 0,01195273 0,04739876 ! behavioral fear response GO:0001662 13 7 0,000 0,01195273 0,04731718 GO:0002209|behavioral defense response, ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01195273 0,04723588 ! rRNA modification GO:0000154 12 7 0,000 0,01195273 0,04715486 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01195273 0,04707411 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01195273 0,04699365 ! response to UV-B GO:0010224 11 7 0,000 0,01195273 0,04691345 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01195273 0,04683353 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01195273 0,04675388 ! intermediate filament organization GO:0045109 11 7 0,000 0,01195273 0,0466745 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01195273 0,04659539 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01195273 0,04651655 ! fibrinolysis GO:0042730 9 7 0,000 0,01195273 0,04643798 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01195273 0,04635967 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01195273 0,04628162 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01195273 0,04620384 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01195273 0,04612631 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01195273 0,04604905 ! response to tropane GO:0014073 13 7 0,000 0,01195273 0,04597204 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01195273 0,0458953 ! melanosome localization GO:0032400 10 7 0,000 0,01195273 0,0458188 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01195273 0,04574257 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01195273 0,04566658 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01195273 0,04559085 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01195273 0,04551537 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01195273 0,04544014 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01195273 0,04536515 ! mast cell activation GO:0045576 9 7 0,000 0,01195273 0,04529042 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01195273 0,04521592 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,01195273 0,04514168 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01195273 0,04506768 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01195273 0,04499392 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01195273 0,0449204 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01195273 0,04484712 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01195273 0,04477408 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01195273 0,04470127 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01195273 0,04462871 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01195273 0,04455637 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01195273 0,04448428 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01195273 0,04441241 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01195273 0,04434078 ! response to tumor cell GO:0002347 12 7 0,000 0,01195273 0,04426938 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01195273 0,0441982 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01195273 0,04412726 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01195273 0,04405654 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,01195273 0,04398605 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01195273 0,04391579 ! diuresis GO:0030146 12 7 0,000 0,01195273 0,04384575 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01195273 0,04377593 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01195273 0,04370633 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01195273 0,04363696 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01195273 0,0435678 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01195273 0,04349886 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01195273 0,04343015 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01195273 0,04336164 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01195273 0,04329336 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01195273 0,04322529 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01195273 0,04315743 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01195273 0,04308978 ! lymph node development GO:0048535 9 7 0,000 0,01195273 0,04302235 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01195273 0,04295513 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01195273 0,04288812 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01195273 0,04282131 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01195273 0,04275472 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01195273 0,04268833 ! ATP catabolic process GO:0006200 10 7 0,000 0,01195273 0,04262214 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01195273 0,04255616 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01195273 0,04249039 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01195273 0,04242482 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01195273 0,04235945 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01195273 0,04229428 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01195273 0,04222931 ! muscle adaptation GO:0043500 12 7 0,000 0,01195273 0,04216454 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01195273 0,04209997 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01195273 0,0420356 ! retina homeostasis GO:0001895 9 7 0,000 0,01195273 0,04197142 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01195273 0,04190744 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01195273 0,04184366 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01195273 0,04178006 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01195273 0,04171667 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01195273 0,04165346 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01195273 0,04159044 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01195273 0,04152762 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01364895 0,0473493 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01364895 0,04727799 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,01364895 0,04720689 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01364895 0,04713601 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01364895 0,04706534 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01364895 0,04699489 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01364895 0,04692464 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01364895 0,0468546 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01364895 0,04678478 ! phosphate transport GO:0006817 10 8 0,000 0,01364895 0,04671516 ! N-glycan processing GO:0006491 12 8 0,000 0,01364895 0,04664574 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01364895 0,04657654 ! UTP metabolic process GO:0046051 8 8 0,000 0,01364895 0,04650753 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01364895 0,04643873 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01364895 0,04637014 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01364895 0,04630175 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01364895 0,04623356 ! succinate metabolic process GO:0006105 14 8 0,000 0,01364895 0,04616557 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01364895 0,04609778 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01364895 0,04603018 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01364895 0,04596279 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01364895 0,04589559 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01364895 0,04582859 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01364895 0,04576179 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01364895 0,04569517 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01364895 0,04562876 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01364895 0,04556253 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01364895 0,0454965 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01364895 0,04543066 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01364895 0,04536501 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01364895 0,04529955 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01364895 0,04523427 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01364895 0,04516919 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01364895 0,04510429 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01364895 0,04503958 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01364895 0,04497505 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01364895 0,04491071 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01364895 0,04484655 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01364895 0,04478257 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01364895 0,04471878 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01364895 0,04465517 ! melanin metabolic process GO:0006582 12 8 0,000 0,01364895 0,04459174 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01364895 0,04452849 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01364895 0,04446542 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01364895 0,04440252 ! macrophage activation GO:0042116 12 8 0,000 0,01364895 0,04433981 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01364895 0,04427727 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01364895 0,04421491 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01364895 0,04415272 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01364895 0,04409071 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01364895 0,04402887 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01364895 0,04396721 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01364895 0,04390571 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01364895 0,04384439 ! ruffle organization GO:0031529 11 8 0,000 0,01364895 0,04378324 ! osteoblast development GO:0002076 13 8 0,000 0,01364895 0,04372226 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01364895 0,04366145 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01364895 0,04360081 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01364895 0,04354034 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01364895 0,04348003 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01364895 0,0434199 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01364895 0,04335992 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01364895 0,04330012 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01364895 0,04324048 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01364895 0,043181 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01364895 0,04312168 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01364895 0,04306253 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01364895 0,04300354 ! segment specification GO:0007379 10 8 0,000 0,01364895 0,04294471 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01364895 0,04288604 ! cellular extravasation GO:0045123 11 8 0,000 0,01364895 0,04282754 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01364895 0,04276919 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01364895 0,042711 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01364895 0,04265297 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01364895 0,04259509 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01364895 0,04253738 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01364895 0,04247982 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01364895 0,04242241 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01364895 0,04236516 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01364895 0,04230807 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01364895 0,04225112 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01364895 0,04219433 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01364895 0,0421377 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01364895 0,04208121 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01364895 0,04202488 ! icosanoid secretion GO:0032309 12 8 0,000 0,01364895 0,0419687 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01364895 0,04191266 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01364895 0,04185678 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01364895 0,04180105 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01364895 0,04174546 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01364895 0,04169002 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01364895 0,04163473 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01364895 0,04157958 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01364895 0,04152458 ! sterol catabolic process GO:0016127 9 8 0,000 0,01364895 0,04146973 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01364895 0,04141502 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01364895 0,04136045 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01364895 0,04130603 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01364895 0,04125175 ! prophase GO:0051324 11 8 0,000 0,01364895 0,04119762 ! S phase GO:0051320 8 8 0,000 0,01364895 0,04114362 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01364895 0,04108977 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01364895 0,04103606 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01364895 0,04098249 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01364895 0,04092905 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01364895 0,04087576 ! hormone catabolic process GO:0042447 13 8 0,000 0,01364895 0,04082261 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01364895 0,04076959 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01364895 0,04071671 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01364895 0,04066397 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01364895 0,04061136 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01364895 0,0405589 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01364895 0,04050656 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01364895 0,04045436 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01364895 0,0404023 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01364895 0,04035037 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01364895 0,04029857 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01364895 0,0402469 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01364895 0,04019537 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01364895 0,04014397 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01364895 0,0400927 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01364895 0,04004156 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01364895 0,03999055 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01534235 0,04489493 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01534235 0,04483788 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01534235 0,04478098 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01534235 0,04472422 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01534235 0,04466761 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01534235 0,04461114 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01534235 0,04455481 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01534235 0,04449863 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01534235 0,04444259 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01534235 0,04438668 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01534235 0,04433092 ! GTP metabolic process GO:0046039 9 9 0,000 0,01534235 0,0442753 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01534235 0,04421982 ! social behavior GO:0035176 14 9 0,000 0,01534235 0,04416447 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01534235 0,04410927 ! artery development GO:0060840 19 9 0,000 0,01534235 0,0440542 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01534235 0,04399927 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01534235 0,04394447 ! response to pain GO:0048265 16 9 0,000 0,01534235 0,04388982 ! protein complex disassembly GO:0043241 17 9 0,000 0,01534235 0,0438353 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01534235 0,04378091 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01534235 0,04372666 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01534235 0,04367254 ! lung alveolus development GO:0048286 17 9 0,000 0,01534235 0,04361856 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01534235 0,04356471 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01534235 0,04351099 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01534235 0,0434574 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01534235 0,04340395 ! protein targeting to ER GO:0045047 19 9 0,000 0,01534235 0,04335063 ! T cell selection GO:0045058 18 9 0,000 0,01534235 0,04329744 ! endoderm development GO:0007492 12 9 0,000 0,01534235 0,04324438 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01534235 0,04319145 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01534235 0,04313865 ! arginine catabolic process GO:0006527 10 9 0,000 0,01534235 0,04308597 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01534235 0,04303343 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01534235 0,04298101 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01534235 0,04292873 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01534235 0,04287656 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01534235 0,04282453 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01534235 0,04277262 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01534235 0,04272084 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01534235 0,04266918 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01534235 0,04261765 ! mannose metabolic process GO:0006013 9 9 0,000 0,01534235 0,04256624 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01534235 0,04251496 ! receptor clustering GO:0043113 15 9 0,000 0,01534235 0,04246379 ! epithelial cell development GO:0002064 10 9 0,000 0,01534235 0,04241276 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01534235 0,04236184 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01534235 0,04231105 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01534235 0,04226037 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01534235 0,04220982 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01534235 0,04215939 ! motor axon guidance GO:0008045 14 9 0,000 0,01534235 0,04210908 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01534235 0,04205889 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01534235 0,04200882 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01534235 0,04195887 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01534235 0,04190904 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01534235 0,04185933 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01534235 0,04180973 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01534235 0,04176025 ! response to amine stimulus GO:0014075 13 9 0,000 0,01534235 0,04171089 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01534235 0,04166164 ! erythrocyte development GO:0048821 11 9 0,000 0,01534235 0,04161252 ! renal water homeostasis GO:0003091 14 9 0,000 0,01534235 0,0415635 ! postreplication repair GO:0006301 11 9 0,000 0,01534235 0,0415146 ! mRNA cleavage GO:0006379 13 9 0,000 0,01534235 0,04146582 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01534235 0,04141715 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01534235 0,0413686 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01534235 0,04132016 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01534235 0,04127183 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01534235 0,04122361 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01534235 0,04117551 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01534235 0,04112752 ! acid secretion GO:0046717 14 9 0,000 0,01534235 0,04107964 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01534235 0,04103188 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01534235 0,04098422 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01534235 0,04093667 ! purine base metabolic process GO:0006144 18 9 0,000 0,01534235 0,04088924 ! oocyte differentiation GO:0009994 12 9 0,000 0,01534235 0,04084191 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01534235 0,0407947 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01534235 0,04074759 ! spleen development GO:0048536 15 9 0,000 0,01534235 0,04070059 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01534235 0,0406537 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01534235 0,04060692 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01534235 0,04056024 ! detection of calcium ion GO:0005513 13 9 0,000 0,01534235 0,04051368 ! blastocyst formation GO:0001825 12 9 0,000 0,01534235 0,04046722 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01534235 0,04042086 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01534235 0,04037461 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01534235 0,04032847 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01534235 0,04028243 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01534235 0,0402365 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01534235 0,04019068 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01534235 0,04014495 ! prepulse inhibition GO:0060134 14 9 0,000 0,01534235 0,04009933 ! embryonic placenta development GO:0001892 12 9 0,000 0,01534235 0,04005382 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01534235 0,0400084 ! insulin secretion GO:0030073 17 9 0,000 0,01534235 0,03996309 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01534235 0,03991789 ! response to nicotine GO:0035094 16 9 0,000 0,01534235 0,03987278 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01534235 0,03982778 ! nucleus localization GO:0051647 15 9 0,000 0,01534235 0,03978288 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01534235 0,03973808 ! localization within membrane GO:0051668 15 9 0,000 0,01534235 0,03969338 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01703295 0,04401773 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01703295 0,04396832 ! neuron fate specification GO:0048665 11 10 0,000 0,01703295 0,04391903 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01703295 0,04386985 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01703295 0,04382078 ! thyroid gland development GO:0030878 19 10 0,000 0,01703295 0,04377182 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,01703295 0,04372296 ! synapsis GO:0007129 13 10 0,000 0,01703295 0,04367422 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01703295 0,04362559 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01703295 0,04357706 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01703295 0,04352864 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01703295 0,04348033 ! sulfate transport GO:0008272 12 10 0,000 0,01703295 0,04343212 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01703295 0,04338403 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01703295 0,04333604 ! androgen metabolic process GO:0008209 13 10 0,000 0,01703295 0,04328815 ! phospholipid efflux GO:0033700 16 10 0,000 0,01703295 0,04324037 ! hippocampus development GO:0021766 19 10 0,000 0,01703295 0,0431927 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01703295 0,04314513 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01703295 0,04309766 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01703295 0,0430503 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01703295 0,04300305 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01703295 0,0429559 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,01703295 0,04290885 ! pathogenesis GO:0009405 13 10 0,000 0,01703295 0,0428619 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01703295 0,04281506 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01703295 0,04276831 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01703295 0,04272168 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01703295 0,04267514 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01703295 0,0426287 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,01703295 0,04258237 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01703295 0,04253613 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01703295 0,04249 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01703295 0,04244396 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01703295 0,04239803 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01703295 0,04235219 ! response to X-ray GO:0010165 16 10 0,000 0,01703295 0,04230645 ! B cell proliferation GO:0042100 14 10 0,000 0,01703295 0,04226082 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01703295 0,04221528 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01703295 0,04216983 ! forebrain cell migration GO:0021885 17 10 0,000 0,01703295 0,04212449 ! lipid digestion GO:0044241 15 10 0,000 0,01703295 0,04207924 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01703295 0,04203409 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01703295 0,04198904 ! UV protection GO:0009650 14 10 0,000 0,01703295 0,04194409 ! entry into host cell GO:0030260 20 10 0,000 0,01703295 0,04189923 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01703295 0,04185446 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01703295 0,04180979 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01703295 0,04176522 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01703295 0,04172074 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01703295 0,04167636 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01703295 0,04163207 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01703295 0,04158787 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01703295 0,04154377 ! regulation of organ growth GO:0046620 11 10 0,000 0,01703295 0,04149976 ! response to dsRNA GO:0043331 18 10 0,000 0,01703295 0,04145585 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01703295 0,04141203 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01703295 0,0413683 ! embryonic axis specification GO:0000578 12 10 0,000 0,01703295 0,04132466 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01703295 0,04128111 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01703295 0,04123766 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01703295 0,0411943 ! cranial nerve development GO:0021545 12 10 0,000 0,01703295 0,04115103 ! fucose catabolic process GO:0019317 16 10 0,000 0,01703295 0,04110785 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01703295 0,04106476 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01703295 0,04102176 ! protein sumoylation GO:0016925 12 10 0,000 0,01703295 0,04097885 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01703295 0,04093603 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01703295 0,04089329 ! zymogen activation GO:0031638 14 10 0,000 0,01703295 0,04085065 ! salivary gland development GO:0007431 22 10 0,000 0,01703295 0,0408081 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01703295 0,04076564 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01703295 0,04072326 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01703295 0,04068097 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01703295 0,04063877 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,01703295 0,04059666 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01703295 0,04055463 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01703295 0,0405127 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01703295 0,04047084 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01703295 0,04042908 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01703295 0,0403874 ! detection of bacterium GO:0016045 10 10 0,000 0,01703295 0,0403458 ! embryonic gut development GO:0048566 11 10 0,000 0,01703295 0,0403043 ! activation of innate immune response GO:0002218 10 10 0,000 0,01703295 0,04026287 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,01703295 0,04022154 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01703295 0,04018028 ! developmental induction GO:0031128 13 10 0,000 0,01703295 0,04013912 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01703295 0,04009803 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01703295 0,04005703 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01703295 0,04001611 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01703295 0,03997528 ! rRNA transcription GO:0009303 17 11 0,000 0,01872073 0,04389163 ! respiratory burst GO:0045730 14 11 0,000 0,01872073 0,04384693 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01872073 0,04380233 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01872073 0,04375781 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01872073 0,04371339 ! virus-host interaction GO:0019048 17 11 0,000 0,01872073 0,04366905 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,01872073 0,04362481 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,01872073 0,04358065 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,01872073 0,04353659 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,01872073 0,04349261 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01872073 0,04344872 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,01872073 0,04340493 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,01872073 0,04336121 ! mating GO:0007618 14 11 0,000 0,01872073 0,04331759 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01872073 0,04327406 ! T cell proliferation GO:0042098 20 11 0,000 0,01872073 0,04323061 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01872073 0,04318725 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,01872073 0,04314397 ! bone resorption GO:0045453 16 11 0,000 0,01872073 0,04310079 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01872073 0,04305769 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01872073 0,04301467 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01872073 0,04297174 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01872073 0,0429289 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01872073 0,04288614 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01872073 0,04284347 ! syncytium formation GO:0006949 15 11 0,000 0,01872073 0,04280088 ! plasma membrane organization GO:0007009 18 11 0,000 0,01872073 0,04275838 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01872073 0,04271596 ! focal adhesion formation GO:0048041 24 11 0,000 0,01872073 0,04267362 ! mitotic spindle organization GO:0007052 15 11 0,000 0,01872073 0,04263137 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,01872073 0,0425892 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01872073 0,04254712 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01872073 0,04250512 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01872073 0,0424632 ! adult heart development GO:0007512 11 11 0,000 0,01872073 0,04242137 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01872073 0,04237961 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01872073 0,04233794 ! temperature homeostasis GO:0001659 16 11 0,000 0,01872073 0,04229635 ! L-glutamate transport GO:0015813 16 11 0,000 0,01872073 0,04225484 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,01872073 0,04221342 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01872073 0,04217207 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01872073 0,04213081 ! stem cell development GO:0048864 29 11 0,000 0,01872073 0,04208962 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01872073 0,04204852 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01872073 0,0420075 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,01872073 0,04196656 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01872073 0,04192569 ! vasoconstriction GO:0042310 15 11 0,000 0,01872073 0,04188491 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01872073 0,0418442 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01872073 0,04180358 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01872073 0,04176303 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,01872073 0,04172256 ! ribosome assembly GO:0042255 13 11 0,000 0,01872073 0,04168217 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01872073 0,04164186 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,01872073 0,04160163 ! chromatin silencing GO:0006342 19 11 0,000 0,01872073 0,04156147 ! nucleosome positioning GO:0016584 13 11 0,000 0,01872073 0,04152139 ! T cell homeostasis GO:0043029 20 11 0,000 0,01872073 0,04148139 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01872073 0,04144147 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,01872073 0,04140162 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01872073 0,04136185 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01872073 0,04132216 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01872073 0,04128254 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01872073 0,04124299 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01872073 0,04120353 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01872073 0,04116414 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,01872073 0,04112482 ! male genitalia development GO:0030539 13 11 0,000 0,01872073 0,04108558 ! cholesterol efflux GO:0033344 19 11 0,000 0,01872073 0,04104641 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,01872073 0,04100732 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,01872073 0,0409683 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01872073 0,04092936 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01872073 0,04089049 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01872073 0,04085169 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01872073 0,04081297 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01872073 0,04077432 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01872073 0,04073575 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01872073 0,04069725 ! lysogeny GO:0030069 18 11 0,000 0,01872073 0,04065882 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,01872073 0,04062046 ! acrosome reaction GO:0007340 13 11 0,000 0,01872073 0,04058217 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01872073 0,04054396 ! lactation GO:0007595 20 12 0,000 0,02040572 0,0441516 ! reproductive cellular process GO:0048610 14 12 0,000 0,02040572 0,04411011 ! tRNA modification GO:0006400 14 12 0,000 0,02040572 0,04406869 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,02040572 0,04402735 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,02040572 0,04398608 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,02040572 0,0439449 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,02040572 0,04390379 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,02040572 0,04386276 ! non-recombinational repair GO:0000726 19 12 0,000 0,02040572 0,0438218 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,02040572 0,04378093 ! peroxisomal transport GO:0043574 21 12 0,000 0,02040572 0,04374012 ! cartilage condensation GO:0001502 18 12 0,000 0,02040572 0,0436994 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,02040572 0,04365875 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,02040572 0,04361817 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,02040572 0,04357767 ! heart looping GO:0001947 15 12 0,000 0,02040572 0,04353725 ! palate development GO:0060021 15 12 0,000 0,02040572 0,0434969 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,02040572 0,04345662 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,02040572 0,04341642 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,02040572 0,0433763 ! arginine metabolic process GO:0006525 13 12 0,000 0,02040572 0,04333624 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,02040572 0,04329627 ! methionine metabolic process GO:0006555 13 12 0,000 0,02040572 0,04325636 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,02040572 0,04321653 ! Golgi organization GO:0007030 18 12 0,000 0,02040572 0,04317677 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,02040572 0,04313709 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,02040572 0,04309748 ! monoamine transport GO:0015844 13 12 0,000 0,02040572 0,04305794 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02040572 0,04301847 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,02040572 0,04297908 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,02040572 0,04293976 ! L-amino acid transport GO:0015807 20 12 0,000 0,02040572 0,0429005 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,02040572 0,04286133 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,02040572 0,04282222 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,02040572 0,04278318 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02040572 0,04274422 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,02040572 0,04270533 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,02040572 0,0426665 ! cerebellum development GO:0021549 13 12 0,000 0,02040572 0,04262775 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,02040572 0,04258907 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,02040572 0,04255046 ! histone acetylation GO:0016573 23 12 0,000 0,02040572 0,04251191 ! histone methylation GO:0016571 15 12 0,000 0,02040572 0,04247344 ! autonomic nervous system development GO:0048483 23 12 0,000 0,02040572 0,04243504 ! gland morphogenesis GO:0022612 23 12 0,000 0,02040572 0,0423967 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,02040572 0,04235844 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,02040572 0,04232025 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,02040572 0,04228212 ! response to gamma radiation GO:0010332 20 12 0,000 0,02040572 0,04224406 ! regulation of epidermis development GO:0045682 17 12 0,000 0,02040572 0,04220607 ! intestinal absorption GO:0050892 19 12 0,000 0,02040572 0,04216815 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,02040572 0,0421303 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,02040572 0,04209251 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,02040572 0,0420548 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,02040572 0,04201715 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,02040572 0,04197956 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,02040572 0,04194205 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,02040572 0,0419046 ! microspike assembly GO:0030035 23 12 0,000 0,02040572 0,04186722 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,02040572 0,0418299 ! response to cold GO:0009409 14 12 0,000 0,02040572 0,04179266 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,02208791 0,04519767 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,02208791 0,0451575 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02208791 0,04511739 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02208791 0,04507736 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,02208791 0,0450374 ! water transport GO:0006833 17 13 0,000 0,02208791 0,04499751 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02208791 0,04495769 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02208791 0,04491794 ! lipid localization GO:0010876 24 13 0,000 0,02208791 0,04487826 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02208791 0,04483865 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02208791 0,04479911 ! organelle fusion GO:0048284 28 13 0,000 0,02208791 0,04475963 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02208791 0,04472023 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02208791 0,0446809 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,02208791 0,04464164 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02208791 0,04460245 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02208791 0,04456332 ! response to hexose stimulus GO:0009746 19 13 0,000 0,02208791 0,04452426 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,02208791 0,04448528 ! glutamate metabolic process GO:0006536 18 13 0,000 0,02208791 0,04444636 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02208791 0,0444075 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02208791 0,04436872 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02208791 0,04433 ! NAD metabolic process GO:0019674 21 13 0,000 0,02208791 0,04429136 ! exocrine system development GO:0035272 27 13 0,000 0,02208791 0,04425277 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02208791 0,04421426 ! bone mineralization GO:0030282 15 13 0,000 0,02208791 0,04417581 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02208791 0,04413743 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02208791 0,04409912 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02208791 0,04406087 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02208791 0,04402269 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,02208791 0,04398458 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02208791 0,04394653 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,02208791 0,04390854 ! genitalia development GO:0048806 15 13 0,000 0,02208791 0,04387063 ! regulation of cellular pH GO:0030641 20 13 0,000 0,02208791 0,04383277 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,02208791 0,04379499 ! cellular pigmentation GO:0033059 24 13 0,000 0,02208791 0,04375727 ! tissue regeneration GO:0042246 21 13 0,000 0,02208791 0,04371961 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02208791 0,04368202 ! cofactor transport GO:0051181 19 13 0,000 0,02208791 0,04364449 ! NADP metabolic process GO:0006739 18 13 0,000 0,02208791 0,04360703 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02208791 0,04356963 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02208791 0,04353229 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02208791 0,04349502 ! gas transport GO:0015669 18 13 0,000 0,02208791 0,04345781 ! regulation of RNA stability GO:0043487 28 13 0,000 0,02208791 0,04342067 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02208791 0,04338359 ! regulation of axon extension GO:0030516 23 13 0,000 0,02208791 0,04334657 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,02208791 0,04330962 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02208791 0,04327273 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02208791 0,0432359 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02208791 0,04319914 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02208791 0,04316243 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02208791 0,04312579 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,0237673 0,04636539 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,0237673 0,0463261 ! superoxide anion generation GO:0042554 18 14 0,000 0,0237673 0,04628687 ! neuron maturation GO:0042551 21 14 0,000 0,0237673 0,04624771 ! regulation of S phase GO:0033261 18 14 0,000 0,0237673 0,04620862 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,0237673 0,04616959 ! myotube differentiation GO:0014902 21 14 0,000 0,0237673 0,04613063 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,0237673 0,04609173 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,0237673 0,0460529 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,0237673 0,04601414 ! inositol metabolic process GO:0006020 20 14 0,000 0,0237673 0,04597544 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,0237673 0,0459368 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,0237673 0,04589823 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,0237673 0,04585973 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,0237673 0,04582129 ! gene silencing by RNA GO:0031047 20 14 0,000 0,0237673 0,04578291 ! response to cAMP GO:0051591 19 14 0,000 0,0237673 0,0457446 ! limbic system development GO:0021761 25 14 0,000 0,0237673 0,04570635 ! startle response GO:0001964 21 14 0,000 0,0237673 0,04566817 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,0237673 0,04563005 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,0237673 0,04559199 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,0237673 0,045554 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,0237673 0,04551607 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,0237673 0,0454782 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,0237673 0,0454404 ! glycine metabolic process GO:0006544 22 14 0,000 0,0237673 0,04540265 ! pituitary gland development GO:0021983 23 14 0,000 0,0237673 0,04536498 ! cellular response to starvation GO:0009267 21 14 0,000 0,0237673 0,04532736 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,0237673 0,04528981 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,0237673 0,04525231 ! regulation of heart rate GO:0002027 23 14 0,000 0,0237673 0,04521488 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,0237673 0,04517752 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,0237673 0,04514021 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,0237673 0,04510297 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,0237673 0,04506578 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,0237673 0,04502866 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,0237673 0,0449916 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,0237673 0,0449546 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,0237673 0,04491766 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,0237673 0,04488078 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,0237673 0,04484397 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,0237673 0,04480721 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0237673 0,04477051 ! mRNA splice site selection GO:0006376 26 14 0,000 0,0237673 0,04473387 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,0237673 0,0446973 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,0237673 0,04466078 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,0237673 0,04462432 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,0237673 0,04458792 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,0237673 0,04455159 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,0237673 0,04451531 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,0237673 0,04447908 ! muscle maintenance GO:0046716 19 14 0,000 0,0237673 0,04444292 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,0237673 0,04440682 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,0237673 0,04437078 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,0237673 0,04433479 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,0237673 0,04429886 ! cell killing GO:0001906 20 14 0,000 0,0237673 0,04426299 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,0237673 0,04422718 ! cilium assembly GO:0042384 20 14 0,000 0,0237673 0,04419143 ! peptide hormone secretion GO:0030072 23 14 0,000 0,0237673 0,04415573 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,02544391 0,04723244 ! metencephalon development GO:0022037 19 15 0,000 0,02544391 0,04719435 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02544391 0,04715632 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,02544391 0,04711835 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,02544391 0,04708044 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,02544391 0,0470426 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,02544391 0,04700481 ! lipid phosphorylation GO:0046834 23 15 0,000 0,02544391 0,04696709 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,02544391 0,04692942 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,02544391 0,04689182 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,02544391 0,04685428 ! bile acid metabolic process GO:0008206 22 15 0,000 0,02544391 0,04681679 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,02544391 0,04677937 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,02544391 0,04674201 ! adult walking behavior GO:0007628 25 15 0,000 0,02544391 0,0467047 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02544391 0,04666746 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,02544391 0,04663027 ! myoblast differentiation GO:0045445 27 15 0,000 0,02544391 0,04659315 ! centrosome cycle GO:0007098 16 15 0,000 0,02544391 0,04655608 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,02544391 0,04651907 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,02544391 0,04648212 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,02544391 0,04644523 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,02544391 0,0464084 ! cerebral cortex development GO:0021987 29 15 0,000 0,02544391 0,04637163 ! response to osmotic stress GO:0006970 22 15 0,000 0,02544391 0,04633491 ! vesicle coating GO:0006901 25 15 0,000 0,02544391 0,04629825 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,02544391 0,04626165 ! DNA integration GO:0015074 22 15 0,000 0,02544391 0,04622511 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,02544391 0,04618863 ! peptide secretion GO:0002790 27 15 0,000 0,02544391 0,0461522 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,02544391 0,04611583 ! regulation of vasodilation GO:0042312 24 15 0,000 0,02544391 0,04607952 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,02544391 0,04604327 ! neuron recognition GO:0008038 22 15 0,000 0,02544391 0,04600707 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,02544391 0,04597093 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,02544391 0,04593485 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,02544391 0,04589882 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,02544391 0,04586285 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,02544391 0,04582693 ! biomineral formation GO:0031214 18 15 0,000 0,02544391 0,04579107 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,02544391 0,04575527 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,02544391 0,04571953 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,02544391 0,04568383 ! dopamine metabolic process GO:0042417 30 15 0,000 0,02544391 0,0456482 ! organic cation transport GO:0015695 19 15 0,000 0,02544391 0,04561262 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,02544391 0,0455771 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,02544391 0,04554163 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,02544391 0,04550622 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,02544391 0,04547086 ! defense response to virus GO:0051607 27 15 0,000 0,02544391 0,04543555 ! peptide hormone processing GO:0016486 19 15 0,000 0,02544391 0,0454003 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,02544391 0,04536511 ! protein secretion GO:0009306 27 16 0,000 0,02711773 0,048312 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,02711773 0,0482746 ! hormone secretion GO:0046879 25 16 0,000 0,02711773 0,04823727 ! bone remodeling GO:0046849 24 16 0,000 0,02711773 0,04819999 ! endothelial cell migration GO:0043542 22 16 0,000 0,02711773 0,04816277 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,02711773 0,04812561 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,02711773 0,0480885 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02711773 0,04805145 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,02711773 0,04801446 ! glial cell development GO:0021782 24 16 0,000 0,02711773 0,04797753 ! patterning of blood vessels GO:0001569 24 16 0,000 0,02711773 0,04794065 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,02711773 0,04790383 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,02711773 0,04786707 ! protein polyubiquitination GO:0000209 26 16 0,000 0,02711773 0,04783036 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,02711773 0,04779371 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,02711773 0,04775711 ! fructose metabolic process GO:0006000 20 16 0,000 0,02711773 0,04772057 ! regulation of protein binding GO:0043393 27 16 0,000 0,02711773 0,04768409 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,02711773 0,04764766 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,02711773 0,04761129 ! protein export from nucleus GO:0006611 24 16 0,000 0,02711773 0,04757497 ! negative regulation of immune response GO:0050777 28 16 0,000 0,02711773 0,04753871 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,02711773 0,0475025 ! DNA replication initiation GO:0006270 25 16 0,000 0,02711773 0,04746635 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,02711773 0,04743026 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,02711773 0,04739422 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,02711773 0,04735823 ! diencephalon development GO:0021536 25 16 0,000 0,02711773 0,0473223 ! oogenesis GO:0048477 23 16 0,000 0,02711773 0,04728642 ! neural crest cell migration GO:0001755 24 16 0,000 0,02711773 0,0472506 ! G1 phase GO:0051318 27 16 0,000 0,02711773 0,04721483 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,02711773 0,04717911 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02711773 0,04714345 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,02711773 0,04710785 ! steroid catabolic process GO:0006706 22 16 0,000 0,02711773 0,04707229 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02711773 0,04703679 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,02711773 0,04700135 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,02711773 0,04696595 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,02711773 0,04693062 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,02711773 0,04689533 ! sperm-egg recognition GO:0035036 16 16 0,000 0,02711773 0,0468601 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,02711773 0,04682492 ! nerve development GO:0021675 18 16 0,000 0,02711773 0,04678979 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,02711773 0,04675471 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,02711773 0,04671969 ! negative regulation of translation GO:0017148 22 16 0,000 0,02711773 0,04668472 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,02878878 0,04952445 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,02878878 0,04948744 ! negative regulation of defense response GO:0031348 19 17 0,000 0,02878878 0,04945048 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,02878878 0,04941358 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,02878878 0,04937673 ! glycerol metabolic process GO:0006071 20 17 0,000 0,02878878 0,04933993 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,02878878 0,04930319 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,02878878 0,04926651 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02878878 0,04922988 ! signal complex assembly GO:0007172 29 17 0,000 0,02878878 0,04919331 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,02878878 0,04915679 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,02878878 0,04912032 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,02878878 0,04908391 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,02878878 0,04904755 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,02878878 0,04901124 ! memory GO:0007613 25 17 0,000 0,02878878 0,04897499 ! keratinization GO:0031424 17 17 0,000 0,02878878 0,0489388 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,02878878 0,04890265 ! retinoid metabolic process GO:0001523 22 17 0,000 0,02878878 0,04886656 GO:0016101|diterpenoid metabolic process, ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,02878878 0,04883052 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,02878878 0,04879454 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,02878878 0,04875861 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,02878878 0,04872273 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,02878878 0,0486869 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,02878878 0,04865113 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,02878878 0,04861541 ! membrane budding GO:0006900 29 17 0,000 0,02878878 0,04857974 ! heme metabolic process GO:0042168 27 17 0,000 0,02878878 0,04854413 ! actin filament bundle formation GO:0051017 26 17 0,000 0,02878878 0,04850856 ! neuromuscular junction development GO:0007528 23 17 0,000 0,02878878 0,04847305 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,02878878 0,04843759 ! body fluid secretion GO:0007589 27 17 0,000 0,02878878 0,04840219 ! stem cell differentiation GO:0048863 36 17 0,000 0,02878878 0,04836683 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02878878 0,04833153 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,02878878 0,04829627 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,02878878 0,04826107 ! sensory perception of pain GO:0019233 23 17 0,000 0,02878878 0,04822592 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,02878878 0,04819082 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,02878878 0,04815578 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,02878878 0,04812078 ! synaptogenesis GO:0007416 24 17 0,000 0,02878878 0,04808583 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,02878878 0,04805094 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02878878 0,04801609 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,02878878 0,0479813 ! cell-cell junction organization GO:0045216 25 17 0,000 0,02878878 0,04794655 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,02878878 0,04791186 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,02878878 0,04787722 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,02878878 0,04784262 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,02878878 0,04780808 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,02878878 0,04777359 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,02878878 0,04773914 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,03045705 0,05046917 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,03045705 0,05043284 ! positive regulation of translation GO:0045727 28 18 0,000 0,03045705 0,05039656 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,03045705 0,05036032 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,03045705 0,05032415 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,03045705 0,05028802 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,03045705 0,05025195 ! cAMP metabolic process GO:0046058 33 18 0,000 0,03045705 0,05021592 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,03045705 0,05017995 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,03045705 0,05014403 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,03045705 0,05010816 ! axis specification GO:0009798 26 18 0,000 0,03045705 0,05007235 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,03045705 0,05003658 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,03045705 0,05000086 ! pancreas development GO:0031016 26 18 0,000 0,03045705 0,0499652 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,03045705 0,04992959 ! glutamine metabolic process GO:0006541 23 18 0,000 0,03045705 0,04989403 ! response to retinoic acid GO:0032526 25 18 0,000 0,03045705 0,04985851 ! pigmentation during development GO:0048066 31 18 0,000 0,03045705 0,04982305 ! central nervous system neuron development GO:0021954 30 18 0,000 0,03045705 0,04978764 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,03045705 0,04975228 ! fucose metabolic process GO:0006004 26 18 0,000 0,03045705 0,04971697 ! response to fungus GO:0009620 19 18 0,000 0,03045705 0,04968171 ! peptide cross-linking GO:0018149 31 18 0,000 0,03045705 0,0496465 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,03045705 0,04961134 ! heart process GO:0003015 27 18 0,000 0,03045705 0,04957623 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,03045705 0,04954117 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,03045705 0,04950616 ! visual learning GO:0008542 35 18 0,000 0,03045705 0,04947119 ! somitogenesis GO:0001756 24 18 0,000 0,03045705 0,04943628 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,03045705 0,04940142 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,03045705 0,0493666 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,03045705 0,04933184 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,03045705 0,04929712 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,03045705 0,04926246 ! vitamin transport GO:0051180 24 18 0,000 0,03045705 0,04922784 ! hormone transport GO:0009914 27 18 0,000 0,03045705 0,04919327 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,03045705 0,04915875 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,03045705 0,04912427 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,03045705 0,04908985 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,03045705 0,04905547 ! cell-cell recognition GO:0009988 20 18 0,000 0,03045705 0,04902114 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,03045705 0,04898686 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,03045705 0,04895263 ! regulation of glucose import GO:0046324 21 18 0,000 0,03045705 0,04891844 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,03045705 0,04888431 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,03045705 0,04885022 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,03045705 0,04881618 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,03045705 0,04878218 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,03212255 0,05141396 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,03212255 0,05137821 ! positive regulation of ossification GO:0045778 30 19 0,000 0,03212255 0,0513425 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,03212255 0,05130685 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,03212255 0,05127124 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,03212255 0,05123569 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,03212255 0,05120018 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,03212255 0,05116472 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,03212255 0,05112932 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,03212255 0,05109396 ! regeneration GO:0031099 32 19 0,000 0,03212255 0,05105865 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,03212255 0,05102338 ! response to alkaloid GO:0043279 32 19 0,000 0,03212255 0,05098817 ! sensory perception of taste GO:0050909 23 19 0,000 0,03212255 0,05095301 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,03212255 0,05091789 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,03212255 0,05088282 ! smooth muscle contraction GO:0006939 36 19 0,000 0,03212255 0,05084781 ! peroxisome organization GO:0007031 29 19 0,000 0,03212255 0,05081283 ! digestive system process GO:0022600 30 19 0,000 0,03212255 0,05077791 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,03212255 0,05074304 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,03212255 0,05070821 ! response to vitamin A GO:0033189 26 19 0,000 0,03212255 0,05067343 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,03212255 0,0506387 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,03212255 0,05060401 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,03212255 0,05056938 ! response to starvation GO:0042594 30 19 0,000 0,03212255 0,05053479 ! sex determination GO:0007530 29 19 0,000 0,03212255 0,05050025 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,03212255 0,05046575 ! plasma membrane fusion GO:0045026 23 19 0,000 0,03212255 0,0504313 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,03212255 0,0503969 ! cytolysis GO:0019835 20 19 0,000 0,03212255 0,05036255 ! renal system process GO:0003014 35 19 0,000 0,03212255 0,05032824 ! vasodilation GO:0042311 33 19 0,000 0,03212255 0,05029398 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,03212255 0,05025977 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,03212255 0,0502256 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,03212255 0,05019148 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,03212255 0,05015741 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,03212255 0,05012338 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,03212255 0,0500894 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,03212255 0,05005546 ! sarcomere organization GO:0045214 23 19 0,000 0,03212255 0,05002157 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,03212255 0,04998773 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,03212255 0,04995393 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,03212255 0,04992018 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,03212255 0,04988647 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,03212255 0,04985281 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,03212255 0,04981919 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,03212255 0,04978562 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,03212255 0,0497521 ! protein stabilization GO:0050821 26 19 0,000 0,03212255 0,04971861 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,03378528 0,05225699 ! iron ion transport GO:0006826 37 20 0,000 0,03378528 0,05222187 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,03378528 0,0521868 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,03378528 0,05215178 GO:0006044|N-acetylglucosamine metabolic process, ! response to vitamin GO:0033273 29 20 0,000 0,03378528 0,0521168 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,03378528 0,05208187 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,03378528 0,05204699 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,03378528 0,05201215 ! spinal cord development GO:0021510 31 20 0,000 0,03378528 0,05197736 ! response to ethanol GO:0045471 37 20 0,000 0,03378528 0,05194261 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,03378528 0,05190792 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,03378528 0,05187326 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,03378528 0,05183866 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,03378528 0,0518041 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,03378528 0,05176959 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,03378528 0,05173512 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,03378528 0,0517007 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,03378528 0,05166632 ! pallium development GO:0021543 38 20 0,000 0,03378528 0,05163199 ! DNA modification GO:0006304 28 20 0,000 0,03378528 0,05159771 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,03378528 0,05156347 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,03378528 0,05152928 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,03378528 0,05149513 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,03378528 0,05146103 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,03378528 0,05142697 ! collagen catabolic process GO:0030574 25 20 0,000 0,03378528 0,05139296 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,03378528 0,05135899 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,03378528 0,05132507 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,03378528 0,05129119 ! alditol metabolic process GO:0019400 24 20 0,000 0,03378528 0,05125735 ! actin filament-based movement GO:0030048 34 20 0,000 0,03378528 0,05122357 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,03544525 0,05370493 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,03544525 0,05366958 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,03544525 0,05363427 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,03544525 0,053599 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,03544525 0,05356379 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,03544525 0,05352862 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,03544525 0,0534935 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,03544525 0,05345842 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,03544525 0,05342339 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,03544525 0,0533884 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,03544525 0,05335346 ! protein amino acid acylation GO:0043543 37 21 0,000 0,03544525 0,05331857 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,03544525 0,05328372 ! vesicle docking GO:0048278 27 21 0,000 0,03544525 0,05324891 ! phototransduction GO:0007602 25 21 0,000 0,03544525 0,05321416 ! dendrite development GO:0016358 35 21 0,000 0,03544525 0,05317944 ! visual behavior GO:0007632 39 21 0,000 0,03544525 0,05314478 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,03544525 0,05311015 ! ovarian follicle development GO:0001541 30 21 0,000 0,03544525 0,05307558 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,03544525 0,05304105 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,03544525 0,05300656 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,03544525 0,05297212 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,03544525 0,05293772 ! cell aging GO:0007569 32 21 0,000 0,03544525 0,05290337 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,03544525 0,05286906 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,03544525 0,05283479 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,03544525 0,05280057 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,03544525 0,0527664 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,03544525 0,05273227 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,03544525 0,05269818 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,03544525 0,05266414 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,03544525 0,05263014 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,03544525 0,05259618 ! fatty acid transport GO:0015908 30 21 0,000 0,03544525 0,05256227 ! immunoglobulin production GO:0002377 33 21 0,000 0,03544525 0,05252841 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,03544525 0,05249458 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,03544525 0,0524608 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,03544525 0,05242707 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,03544525 0,05239337 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,03544525 0,05235972 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,03544525 0,05232611 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,03544525 0,05229255 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,03544525 0,05225903 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,03544525 0,05222555 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,03544525 0,05219212 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,03544525 0,05215872 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,03544525 0,05212537 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,03544525 0,05209207 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,03544525 0,0520588 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,03710247 0,054458 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,03710247 0,05442327 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,03710247 0,05438858 ! viral genome replication GO:0019079 29 22 0,000 0,03710247 0,05435394 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,03710247 0,05431934 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,03710247 0,05428479 ! leukocyte adhesion GO:0007159 38 22 0,000 0,03710247 0,05425027 ! molting cycle process GO:0022404 40 22 0,000 0,03710247 0,05421581 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,03710247 0,05418139 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,03710247 0,05414701 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,03710247 0,05411267 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,03710247 0,05407838 ! vasculogenesis GO:0001570 33 22 0,000 0,03710247 0,05404413 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,03710247 0,05400993 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,03710247 0,05397576 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,03710247 0,05394165 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,03710247 0,05390757 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,03710247 0,05387354 ! lysosome organization GO:0007040 37 22 0,000 0,03710247 0,05383955 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,03710247 0,0538056 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,03710247 0,0537717 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,03710247 0,05373784 ! regulation of behavior GO:0050795 38 22 0,000 0,03710247 0,05370402 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,03710247 0,05367024 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,03710247 0,05363651 ! membrane depolarization GO:0051899 35 22 0,000 0,03710247 0,05360282 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,03710247 0,05356917 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,03710247 0,05353556 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,03710247 0,053502 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,03710247 0,05346847 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,03710247 0,05343499 ! blastocyst development GO:0001824 37 22 0,000 0,03710247 0,05340155 ! neural tube closure GO:0001843 33 22 0,000 0,03710247 0,05336816 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,03710247 0,0533348 ! protein tetramerization GO:0051262 39 22 0,000 0,03710247 0,05330149 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,03875693 0,05564354 ! neuron fate commitment GO:0048663 32 23 0,000 0,03875693 0,05560883 ! embryonic pattern specification GO:0009880 31 23 0,000 0,03875693 0,05557416 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,03875693 0,05553953 ! myelination GO:0042552 35 23 0,000 0,03875693 0,05550495 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,03875693 0,05547041 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,03875693 0,05543591 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,03875693 0,05540146 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,03875693 0,05536705 ! vesicle targeting GO:0006903 32 23 0,000 0,03875693 0,05533268 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,03875693 0,05529835 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,03875693 0,05526407 ! osteoblast differentiation GO:0001649 40 23 0,000 0,03875693 0,05522983 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,03875693 0,05519563 ! interaction with host GO:0051701 37 23 0,000 0,03875693 0,05516148 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,03875693 0,05512736 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,03875693 0,05509329 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,03875693 0,05505926 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,03875693 0,05502528 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,03875693 0,05499133 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,03875693 0,05495743 ! cell fate determination GO:0001709 45 23 0,000 0,03875693 0,05492357 ! pentose metabolic process GO:0019321 31 23 0,000 0,03875693 0,05488975 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,03875693 0,05485597 ! spermatid development GO:0007286 33 23 0,000 0,03875693 0,05482223 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,03875693 0,05478854 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,03875693 0,05475488 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,03875693 0,05472127 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,03875693 0,0546877 ! telomere organization GO:0032200 32 23 0,000 0,03875693 0,05465417 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,03875693 0,05462068 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,03875693 0,05458723 ! regulation of amine transport GO:0051952 38 23 0,000 0,03875693 0,05455382 ! liver development GO:0001889 40 23 0,000 0,03875693 0,05452046 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,04040865 0,05680922 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,04040865 0,05677452 ! initiation of viral infection GO:0019059 42 24 0,000 0,04040865 0,05673986 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,04040865 0,05670524 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,04040865 0,05667067 ! superoxide metabolic process GO:0006801 32 24 0,000 0,04040865 0,05663613 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,04040865 0,05660164 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,04040865 0,05656719 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,04040865 0,05653278 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,04040865 0,05649841 ! sperm motility GO:0030317 27 24 0,000 0,04040865 0,05646409 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,04040865 0,05642981 ! vacuole organization GO:0007033 39 24 0,000 0,04040865 0,05639557 ! receptor metabolic process GO:0043112 37 24 0,000 0,04040865 0,05636137 ! neural crest cell development GO:0014032 39 24 0,000 0,04040865 0,05632721 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,04040865 0,05629309 ! primary neural tube formation GO:0014020 35 24 0,000 0,04040865 0,05625901 ! negative regulation of cell development GO:0010721 56 24 0,000 0,04040865 0,05622498 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,04040865 0,05619099 ! base-excision repair GO:0006284 31 24 0,000 0,04040865 0,05615703 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,04040865 0,05612312 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,04040865 0,05608925 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,04040865 0,05605542 ! glutathione metabolic process GO:0006749 29 24 0,000 0,04040865 0,05602163 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,04040865 0,05598789 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,04040865 0,05595418 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,04040865 0,05592051 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,04205762 0,05816748 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,04205762 0,05813253 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,04205762 0,05809761 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,04205762 0,05806274 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,04205762 0,05802791 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,04205762 0,05799312 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,04205762 0,05795837 ! peptide transport GO:0015833 43 25 0,000 0,04205762 0,05792367 ! male gonad development GO:0008584 33 25 0,000 0,04205762 0,057889 ! iron ion homeostasis GO:0055072 39 25 0,000 0,04205762 0,05785438 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,04205762 0,0578198 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,04205762 0,05778526 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,04205762 0,05775076 ! phospholipid transport GO:0015914 35 25 0,000 0,04205762 0,0577163 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,04205762 0,05768189 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,04205762 0,05764751 ! detection of light stimulus GO:0009583 30 25 0,000 0,04205762 0,05761318 ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,04205762 0,05757888 ! leukocyte proliferation GO:0070661 39 25 0,000 0,04205762 0,05754463 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,04205762 0,05751042 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,04370385 0,059726 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,04370385 0,05969053 ! translational initiation GO:0006413 43 26 0,000 0,04370385 0,05965511 ! regulation of pH GO:0006885 36 26 0,000 0,04370385 0,05961973 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,04370385 0,05958439 ! circadian rhythm GO:0007623 42 26 0,000 0,04370385 0,05954909 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,04370385 0,05951383 ! post-embryonic development GO:0009791 42 26 0,000 0,04370385 0,05947862 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,04370385 0,05944344 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,04370385 0,05940831 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,04370385 0,05937322 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,04370385 0,05933817 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,04370385 0,05930316 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,04370385 0,0592682 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,04370385 0,05923327 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,04370385 0,05919839 ! regulation of coagulation GO:0050818 39 26 0,000 0,04370385 0,05916354 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,04534735 0,0613523 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,04534735 0,06131623 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,04534735 0,0612802 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,04534735 0,06124422 ! membrane docking GO:0022406 39 27 0,000 0,04534735 0,06120828 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,04534735 0,06117238 ! catechol metabolic process GO:0009712 43 27 0,000 0,04534735 0,06113652 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,04534735 0,0611007 ! acute-phase response GO:0006953 42 27 0,000 0,04534735 0,06106493 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,04534735 0,0610292 ! myofibril assembly GO:0030239 36 27 0,000 0,04534735 0,06099351 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,04534735 0,06095786 ! response to ionizing radiation GO:0010212 47 27 0,000 0,04534735 0,06092226 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,04534735 0,06088669 ! natural killer cell activation GO:0030101 35 27 0,000 0,04534735 0,06085117 ! lipid oxidation GO:0034440 38 27 0,000 0,04534735 0,06081569 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,04534735 0,06078025 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,04534735 0,06074485 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,04534735 0,06070949 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,04534735 0,06067417 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,04534735 0,0606389 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,04534735 0,06060366 ! gene silencing GO:0016458 41 27 0,000 0,04534735 0,06056847 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,04698812 0,06272354 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,04698812 0,06268716 ! phenol metabolic process GO:0018958 44 28 0,000 0,04698812 0,06265082 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,04698812 0,06261452 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,04698812 0,06257827 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,04698812 0,06254205 ! cell junction assembly GO:0034329 56 28 0,000 0,04698812 0,06250588 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,04698812 0,06246975 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,04698812 0,06243366 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,04698812 0,06239761 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,04698812 0,06236161 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,04698812 0,06232564 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,04698812 0,06228972 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,04698812 0,06225384 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,04698812 0,062218 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,04698812 0,0621822 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,04698812 0,06214644 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,04698812 0,06211073 ! mesoderm formation GO:0001707 46 28 0,000 0,04698812 0,06207505 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,04698812 0,06203942 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,04698812 0,06200382 ! ensheathment of neurons GO:0007272 43 28 0,000 0,04698812 0,06196827 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,04698812 0,06193276 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,04698812 0,06189729 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,04698812 0,06186186 ! neural tube formation GO:0001841 41 28 0,000 0,04698812 0,06182647 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,04698812 0,06179112 ! placenta development GO:0001890 37 28 0,000 0,04698812 0,06175581 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,04862616 0,06387216 ! regulation of innate immune response GO:0045088 38 29 0,000 0,04862616 0,06383571 ! ovulation cycle process GO:0022602 41 29 0,000 0,04862616 0,06379929 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,04862616 0,06376292 ! protein targeting to membrane GO:0006612 53 29 0,000 0,04862616 0,06372659 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,04862616 0,0636903 ! mismatch repair GO:0006298 34 29 0,000 0,04862616 0,06365405 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,04862616 0,06361784 ! muscle cell development GO:0055001 38 29 0,000 0,04862616 0,06358167 ! formation of primary germ layer GO:0001704 48 29 0,000 0,04862616 0,06354554 ! telencephalon development GO:0021537 52 29 0,000 0,04862616 0,06350946 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,04862616 0,06347342 ! eye morphogenesis GO:0048592 51 29 0,000 0,04862616 0,06343741 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,04862616 0,06340145 ! tissue homeostasis GO:0001894 42 29 0,000 0,04862616 0,06336553 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,05026147 0,06545945 ! collagen metabolic process GO:0032963 40 30 0,000 0,05026147 0,06542241 ! organic anion transport GO:0015711 51 30 0,000 0,05026147 0,0653854 ! cholesterol transport GO:0030301 46 30 0,000 0,05026147 0,06534844 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,05026147 0,06531152 ! spliceosome assembly GO:0000245 49 30 0,000 0,05026147 0,06527464 ! spindle organization GO:0007051 37 30 0,000 0,05026147 0,06523781 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,05026147 0,06520101 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,05026147 0,06516426 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,05026147 0,06512754 ! ceramide metabolic process GO:0006672 43 30 0,000 0,05026147 0,06509087 ! ovulation cycle GO:0042698 43 30 0,000 0,05026147 0,06505424 ! hindbrain development GO:0030902 45 30 0,000 0,05026147 0,06501766 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,05026147 0,06498111 ! adult locomotory behavior GO:0008344 47 30 0,000 0,05026147 0,0649446 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,05026147 0,06490814 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,05026147 0,06487171 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,05026147 0,06483533 ! response to heat GO:0009408 41 30 0,000 0,05026147 0,06479899 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,05026147 0,06476268 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,05026147 0,06472642 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,05189408 0,06679148 ! negative regulation of secretion GO:0051048 49 31 0,000 0,05189408 0,06675412 ! mammary gland development GO:0030879 57 31 0,000 0,05189408 0,06671681 ! glial cell differentiation GO:0010001 55 31 0,000 0,05189408 0,06667954 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,05189408 0,06664231 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,05189408 0,06660512 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,05189408 0,06656797 ! odontogenesis GO:0042476 50 31 0,000 0,05189408 0,06653087 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,05189408 0,0664938 ! segmentation GO:0035282 41 31 0,000 0,05189408 0,06645678 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,05189408 0,0664198 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,05189408 0,06638286 ! metanephros development GO:0001656 58 31 0,000 0,05189408 0,06634596 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,05189408 0,0663091 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,05189408 0,06627228 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,05189408 0,0662355 ! cell fate specification GO:0001708 37 31 0,000 0,05189408 0,06619877 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,05189408 0,06616207 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,05189408 0,06612541 ! RNA modification GO:0009451 40 31 0,000 0,05189408 0,0660888 ! regulation of muscle development GO:0048634 48 32 0,000 0,05352396 0,06812679 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,05352396 0,06808911 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,05352396 0,06805147 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,05352396 0,06801388 ! meiosis I GO:0007127 52 32 0,000 0,05352396 0,06797632 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,05352396 0,06793881 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,05352396 0,06790133 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,05352396 0,0678639 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,05352396 0,06782651 ! peripheral nervous system development GO:0007422 53 32 0,000 0,05352396 0,06778916 ! regulation of protein stability GO:0031647 48 32 0,000 0,05352396 0,06775185 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,05352396 0,06771459 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,05352396 0,06767736 ! cytokine production GO:0001816 44 32 0,000 0,05352396 0,06764017 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,05352396 0,06760303 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,05352396 0,06756593 ! vesicle localization GO:0051648 47 32 0,000 0,05352396 0,06752886 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,05515114 0,06954366 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,05515114 0,06950555 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,05515114 0,06946749 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,05515114 0,06942946 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,05515114 0,06939148 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,05515114 0,06935354 ! sister chromatid segregation GO:0000819 46 33 0,000 0,05515114 0,06931564 ! ear morphogenesis GO:0042471 42 33 0,000 0,05515114 0,06927779 ! actomyosin structure organization GO:0031032 43 33 0,000 0,05515114 0,06923997 ! cell junction organization GO:0034330 63 33 0,000 0,05515114 0,0692022 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,05515114 0,06916447 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,05515114 0,06912677 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,05515114 0,06908912 GO:0042593|glucose homeostasis, ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,05515114 0,06905151 ! female gonad development GO:0008585 49 33 0,000 0,05515114 0,06901394 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,05515114 0,06897642 ! positive regulation of cell development GO:0010720 54 33 0,000 0,05515114 0,06893893 ! lipid homeostasis GO:0055088 55 33 0,000 0,05515114 0,06890148 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,05515114 0,06886408 ! regulation of proteolysis GO:0030162 50 33 0,000 0,05515114 0,06882671 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,05515114 0,06878939 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,05515114 0,0687521 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,05515114 0,06871486 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,05677562 0,07070055 ! mRNA catabolic process GO:0006402 48 34 0,000 0,05677562 0,0706623 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,05677562 0,07062408 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,05677562 0,0705859 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,05677562 0,07054777 ! feeding behavior GO:0007631 45 34 0,000 0,05677562 0,07050968 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,05677562 0,07047163 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,05677562 0,07043361 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,05677562 0,07039565 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,05677562 0,07035772 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,05677562 0,07031983 ! neuron migration GO:0001764 46 34 0,000 0,05677562 0,07028198 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,05677562 0,07024418 ! female gamete generation GO:0007292 43 34 0,000 0,05677562 0,07020641 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,05677562 0,07016868 ! polyol metabolic process GO:0019751 44 34 0,000 0,05677562 0,070131 ! aerobic respiration GO:0009060 47 34 0,000 0,05677562 0,07009336 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,05677562 0,07005575 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,05677562 0,07001819 ! embryonic organ development GO:0048568 45 34 0,000 0,05677562 0,06998067 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,05677562 0,06994318 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,05839739 0,07190257 ! Notch signaling pathway GO:0007219 56 35 0,000 0,05839739 0,0718641 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,05839739 0,07182567 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,05839739 0,07178728 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,05839739 0,07174893 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,05839739 0,07171063 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,05839739 0,07167236 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,05839739 0,07163414 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,05839739 0,07159595 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,05839739 0,07155781 ! glycogen metabolic process GO:0005977 48 35 0,000 0,05839739 0,0715197 ! pigment metabolic process GO:0042440 61 35 0,000 0,05839739 0,07148164 ! protein homooligomerization GO:0051260 52 35 0,000 0,05839739 0,07144362 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,06001647 0,07338537 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,06001647 0,07334638 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,06001647 0,07330743 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,06001647 0,07326852 ! negative regulation of binding GO:0051100 58 36 0,000 0,06001647 0,07322965 ! organic ether metabolic process GO:0018904 46 36 0,000 0,06001647 0,07319082 ! tissue remodeling GO:0048771 62 36 0,000 0,06001647 0,07315203 ! neural tube development GO:0021915 50 36 0,000 0,06001647 0,07311329 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,06001647 0,07307458 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,06001647 0,07303592 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,06001647 0,0729973 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,06001647 0,07295871 ! glucan metabolic process GO:0044042 49 36 0,000 0,06001647 0,07292017 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,06163286 0,07484455 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,06163286 0,07480506 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,06163286 0,0747656 ! learning GO:0007612 67 37 0,000 0,06163286 0,07472619 ! ion transmembrane transport GO:0034220 56 37 0,000 0,06163286 0,07468682 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,06163286 0,07464749 ! regulation of protein secretion GO:0050708 51 37 0,000 0,06163286 0,0746082 ! amino acid activation GO:0043038 52 37 0,000 0,06163286 0,07456895 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,06163286 0,07452975 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,06324656 0,07644093 ! gliogenesis GO:0042063 71 38 0,000 0,06324656 0,07640078 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,06324656 0,07636068 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,06324656 0,07632062 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,06324656 0,07628059 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,06324656 0,07624061 ! phagocytosis GO:0006909 60 38 0,000 0,06324656 0,07620068 ! mesenchymal cell development GO:0014031 64 38 0,000 0,06324656 0,07616078 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,06324656 0,07612093 ! maintenance of location in cell GO:0051651 69 38 0,000 0,06324656 0,07608112 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,06485758 0,07797827 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,06485758 0,07793753 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,06485758 0,07789683 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,06485758 0,07785618 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,06485758 0,07781556 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,06485758 0,07777499 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,06485758 0,07773446 ! male sex differentiation GO:0046661 53 39 0,000 0,06485758 0,07769398 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,06485758 0,07765353 ! chromatin remodeling GO:0006338 68 39 0,000 0,06485758 0,07761313 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,06485758 0,07757277 ! developmental growth GO:0048589 62 39 0,000 0,06485758 0,07753245 ! cell growth GO:0016049 61 39 0,000 0,06485758 0,07749217 ! synapse organization GO:0050808 55 39 0,000 0,06485758 0,07745194 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,06646592 0,0793314 ! regulation of tube size GO:0035150 60 40 0,000 0,06646592 0,07929026 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,06646592 0,07924915 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,06646592 0,07920809 ! peptide metabolic process GO:0006518 56 40 0,000 0,06646592 0,07916707 ! inner ear development GO:0048839 57 40 0,000 0,06646592 0,0791261 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,06646592 0,07908516 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,06646592 0,07904427 ! double-strand break repair GO:0006302 67 40 0,000 0,06646592 0,07900342 ! B cell differentiation GO:0030183 62 40 0,000 0,06646592 0,07896261 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,06646592 0,07892185 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,06646592 0,07888112 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,06646592 0,07884044 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,06807159 0,08070343 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,06807159 0,08066185 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,06807159 0,08062031 ! glucose transport GO:0015758 52 41 0,000 0,06807159 0,08057882 ! endosome transport GO:0016197 71 41 0,000 0,06807159 0,08053737 ! striated muscle contraction GO:0006941 62 41 0,000 0,06807159 0,08049596 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,06807159 0,0804546 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,06807159 0,08041328 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,06807159 0,080372 ! biopolymer methylation GO:0043414 62 41 0,000 0,06807159 0,08033076 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,06807159 0,08028956 ! mitochondrial transport GO:0006839 60 42 0,000 0,06967458 0,08213815 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,06967458 0,08209607 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,06967458 0,08205404 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,06967458 0,08201205 ! cellular component disassembly GO:0022411 64 42 0,000 0,06967458 0,0819701 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,06967458 0,08192819 ! hexose transport GO:0008645 54 42 0,000 0,06967458 0,08188632 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,06967458 0,0818445 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,06967458 0,08180272 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,06967458 0,08176099 ! excretion GO:0007588 63 42 0,000 0,06967458 0,0817193 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,06967458 0,08167764 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,06967458 0,08163604 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,06967458 0,08159447 ! regulation of cell shape GO:0008360 78 42 0,000 0,06967458 0,08155295 ! positive regulation of binding GO:0051099 59 43 0,000 0,07127491 0,08338367 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,07127491 0,08334128 ! leukocyte migration GO:0050900 60 43 0,000 0,07127491 0,08329893 ! neuromuscular process GO:0050905 79 43 0,000 0,07127491 0,08325663 ! activation of caspase activity GO:0006919 65 43 0,000 0,07127491 0,08321436 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,07127491 0,08317215 ! tRNA processing GO:0008033 49 43 0,000 0,07127491 0,08312997 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,07127491 0,08308783 ! vesicle organization GO:0016050 79 43 0,000 0,07127491 0,08304574 ! response to insulin stimulus GO:0032868 63 43 0,000 0,07127491 0,0830037 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,07127491 0,08296169 ! methylation GO:0032259 64 43 0,000 0,07127491 0,08291973 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,07287258 0,08473556 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,07287258 0,08469274 ! glycolysis GO:0006096 53 44 0,000 0,07287258 0,08464997 ! regulation of action potential GO:0001508 71 44 0,000 0,07287258 0,08460724 ! regulation of ion transport GO:0043269 57 44 0,000 0,07287258 0,08456455 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,07287258 0,0845219 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,07287258 0,0844793 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,07287258 0,08443674 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,07287258 0,08439423 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,07287258 0,08435175 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,07287258 0,08430932 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,07287258 0,08426694 ! RNA catabolic process GO:0006401 64 45 0,000 0,07446759 0,08606807 ! positive regulation of defense response GO:0031349 59 45 0,000 0,07446759 0,08602484 ! regulation of translational initiation GO:0006446 64 45 0,000 0,07446759 0,08598166 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,07446759 0,08593852 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,07446759 0,08589542 ! cell recognition GO:0008037 58 45 0,000 0,07446759 0,08585236 ! cell maturation GO:0048469 60 45 0,000 0,07446759 0,08580935 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,07446759 0,08576638 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,07605995 0,0875565 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,07605995 0,0875127 ! cell redox homeostasis GO:0045454 63 46 0,000 0,07605995 0,08746895 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,07605995 0,08742523 ! regulation of ossification GO:0030278 71 46 0,000 0,07605995 0,08738156 ! histone modification GO:0016570 68 46 0,000 0,07605995 0,08733794 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,07605995 0,08729436 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,07764966 0,08907443 ! viral infectious cycle GO:0019058 71 47 0,000 0,07764966 0,08903002 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,07764966 0,08898566 ! endocrine system development GO:0035270 83 47 0,000 0,07764966 0,08894135 ! covalent chromatin modification GO:0016569 75 47 0,000 0,07764966 0,08889708 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,07764966 0,08885285 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,07764966 0,08880867 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,07764966 0,08876453 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,07764966 0,08872043 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,07764966 0,08867638 ! chloride transport GO:0006821 67 48 0,000 0,07923673 0,09044391 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,07923673 0,09039905 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,07923673 0,09035423 ! response to temperature stimulus GO:0009266 62 48 0,000 0,07923673 0,09030946 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,07923673 0,09026473 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,07923673 0,09022004 ! gastrulation GO:0007369 73 48 0,000 0,07923673 0,0901754 ! heart morphogenesis GO:0003007 65 48 0,000 0,07923673 0,0901308 ! regulation of DNA replication GO:0006275 75 48 0,000 0,07923673 0,09008625 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,07923673 0,09004174 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,07923673 0,08999727 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,07923673 0,08995285 ! regulation of endocytosis GO:0030100 63 48 0,000 0,07923673 0,08990848 ! nuclear export GO:0051168 69 48 0,000 0,07923673 0,08986414 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,07923673 0,08981985 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,07923673 0,08977561 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,08082116 0,09152568 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,08082116 0,09148064 ! sensory perception of smell GO:0007608 61 49 0,000 0,08082116 0,09143564 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,08082116 0,09139069 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,08082116 0,09134578 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,08082116 0,09130091 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,08082116 0,09125609 ! germ cell development GO:0007281 68 49 0,000 0,08082116 0,09121132 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,08082116 0,09116658 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,08082116 0,09112189 ! cartilage development GO:0051216 70 49 0,000 0,08082116 0,09107725 ! maintenance of location GO:0051235 84 49 0,000 0,08082116 0,09103265 ! regulation of actin filament length GO:0030832 72 50 0,000 0,08240295 0,09276886 ! ear development GO:0043583 72 50 0,000 0,08240295 0,09272347 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,08240295 0,09267813 ! membrane fusion GO:0006944 80 50 0,000 0,08240295 0,09263284 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,08240295 0,09258758 ! lipid modification GO:0030258 73 50 0,000 0,08240295 0,09254237 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,08240295 0,09249721 ! proton transport GO:0015992 75 50 0,000 0,08240295 0,09245209 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,08240295 0,09240701 ! positive regulation of secretion GO:0051047 71 51 0,000 0,08398211 0,09413199 ! hydrogen transport GO:0006818 77 51 0,000 0,08398211 0,09408614 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,08398211 0,09404034 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,08398211 0,09399457 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,08398211 0,09394886 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,08398211 0,09390318 ! adult behavior GO:0030534 80 51 0,000 0,08398211 0,09385756 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,08398211 0,09381197 ! transition metal ion transport GO:0000041 74 52 0,000 0,08555864 0,09552664 ! regulation of cellular component size GO:0032535 74 52 0,000 0,08555864 0,09548029 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,08555864 0,09543398 ! aging GO:0007568 79 52 0,000 0,08555864 0,09538772 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,08555864 0,09534151 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,08555864 0,09529534 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,08713255 0,09700139 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,08713255 0,09695446 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,08713255 0,09690758 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,08713255 0,09686074 ! kidney development GO:0001822 90 53 0,000 0,08713255 0,09681394 ! single fertilization GO:0007338 59 53 0,000 0,08713255 0,0967672 ! cell projection assembly GO:0030031 76 53 0,000 0,08713255 0,0967205 ! amino acid transport GO:0006865 84 54 0,000 0,08870384 0,09841719 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,08870384 0,09836974 ! glucose catabolic process GO:0006007 66 54 0,000 0,08870384 0,09832233 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,08870384 0,09827497 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,08870384 0,09822765 ! DNA catabolic process GO:0006308 67 54 0,000 0,08870384 0,09818038 ! detection of external stimulus GO:0009581 66 54 0,000 0,08870384 0,09813316 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,08870384 0,09808598 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,08870384 0,09803884 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,08870384 0,09799176 ! exocytosis GO:0006887 74 55 0,000 0,09027252 0,09967681 ! mesoderm development GO:0007498 76 55 0,000 0,09027252 0,09962898 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,09027252 0,09958119 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,09027252 0,09953346 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,09183858 0,10121166 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,09183858 0,10116319 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,09183858 0,10111476 ! carbohydrate transport GO:0008643 74 57 0,000 0,09340204 0,10278694 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,09340204 0,10273778 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,09340204 0,10268867 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,09340204 0,10263961 ! camera-type eye development GO:0043010 88 57 0,000 0,09340204 0,10259059 ! secondary metabolic process GO:0019748 84 57 0,000 0,09340204 0,10254162 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,09340204 0,1024927 ! developmental maturation GO:0021700 75 57 0,000 0,09340204 0,10244382 ! gonad development GO:0008406 79 57 0,000 0,09340204 0,10239499 ! viral reproductive process GO:0022415 87 58 0,000 0,0949629 0,10405654 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,0949629 0,10400698 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,0949629 0,10395748 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,0949629 0,10390802 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,09652116 0,10556285 ! activation of MAPK activity GO:0000187 84 59 0,000 0,09652116 0,10551267 ! lung development GO:0030324 94 59 0,000 0,09652116 0,10546255 ! actin filament organization GO:0007015 95 59 0,000 0,09652116 0,10541247 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,09652116 0,10536244 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,09652116 0,10531246 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,09807682 0,10695908 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,09807682 0,10690839 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,09807682 0,10685774 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,09807682 0,10680715 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,09807682 0,1067566 ! regulation of heart contraction GO:0008016 91 60 0,000 0,09807682 0,1067061 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,09807682 0,10665565 ! fertilization GO:0009566 68 60 0,000 0,09807682 0,10660524 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,09807682 0,10655489 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,0996299 0,10819111 ! meiosis GO:0007126 96 61 0,000 0,0996299 0,10814005 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,0996299 0,10808904 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,0996299 0,10803808 ! urogenital system development GO:0001655 101 61 0,000 0,0996299 0,10798717 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,0996299 0,1079363 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,0996299 0,10788549 ! extracellular matrix organization GO:0030198 103 61 0,000 0,0996299 0,10783472 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,0996299 0,10778399 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,10118039 0,10940992 ! neurotransmitter transport GO:0006836 81 62 0,000 0,10118039 0,10935851 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,10118039 0,10930714 ! respiratory tube development GO:0030323 99 62 0,000 0,10118039 0,10925582 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,10118039 0,10920455 ! meiotic cell cycle GO:0051321 97 62 0,000 0,10118039 0,10915333 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,1027283 0,11077126 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,1027283 0,11071935 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,1027283 0,11066749 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,1027283 0,11061568 ! viral reproduction GO:0016032 92 63 0,000 0,1027283 0,11056392 ! regulation of lipase activity GO:0060191 109 63 0,000 0,1027283 0,1105122 ! appendage morphogenesis GO:0035107 93 64 0,000 0,10427363 0,11212219 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,10427363 0,11206979 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,10427363 0,11201745 ! hexose catabolic process GO:0019320 82 64 0,000 0,10427363 0,11196515 ! respiratory system development GO:0060541 100 64 0,000 0,10427363 0,11191291 ! adaptive immune response GO:0002250 94 64 0,000 0,10427363 0,11186071 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,10581639 0,1134628 ! appendage development GO:0048736 94 65 0,000 0,10581639 0,11340993 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,10581639 0,11335711 ! defense response to bacterium GO:0042742 73 65 0,000 0,10581639 0,11330433 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,10581639 0,11325161 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,10581639 0,11319893 ! activation of immune response GO:0002253 83 65 0,000 0,10581639 0,11314631 ! protein oligomerization GO:0051259 100 65 0,000 0,10581639 0,11309373 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,10735659 0,11468655 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,10735659 0,11463331 ! antigen processing and presentation GO:0019882 96 66 0,000 0,10735659 0,11458011 ! axon guidance GO:0007411 99 66 0,000 0,10735659 0,11452697 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,10735659 0,11447387 ! regulation of immune effector process GO:0002697 101 66 0,000 0,10735659 0,11442083 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,10889421 0,11600588 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,10889421 0,11595217 ! acute inflammatory response GO:0002526 92 68 0,000 0,11042928 0,11753232 ! learning or memory GO:0007611 123 68 0,000 0,11042928 0,11747795 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,11042928 0,11742364 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,11042928 0,11736938 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,11042928 0,11731517 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,11042928 0,11726101 ! rhythmic process GO:0048511 105 68 0,000 0,11042928 0,11720689 ! inorganic anion transport GO:0015698 93 68 0,000 0,11042928 0,11715283 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,11196179 0,11872389 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,11196179 0,11866918 ! response to drug GO:0042493 108 69 0,000 0,11196179 0,11861451 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,11349174 0,12018002 ! humoral immune response GO:0006959 86 70 0,000 0,11349174 0,12012472 ! eye development GO:0001654 111 70 0,000 0,11349174 0,12006946 ! amine transport GO:0015837 101 70 0,000 0,11349174 0,12001426 ! regulation of catabolic process GO:0009894 106 70 0,000 0,11349174 0,1199591 ! muscle cell differentiation GO:0042692 104 71 0,000 0,11501915 0,12151771 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,11501915 0,12146192 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,11501915 0,12140617 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,11501915 0,12135048 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,11501915 0,12129484 ! response to hypoxia GO:0001666 132 72 0,000 0,11654402 0,12284658 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,11654402 0,12279031 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,11654402 0,12273409 ! negative regulation of transport GO:0051051 116 73 0,000 0,11806634 0,12428036 ! regulation of blood pressure GO:0008217 107 73 0,000 0,11806634 0,12422351 ! tube morphogenesis GO:0035239 118 73 0,000 0,11806634 0,12416671 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,11806634 0,12410996 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,11806634 0,12405326 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,11958613 0,12559274 ! response to oxygen levels GO:0070482 137 74 0,000 0,11958613 0,12553542 ! digestion GO:0007586 97 74 0,000 0,11958613 0,12547815 ! protein import into nucleus GO:0006606 118 74 0,000 0,11958613 0,12542093 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,11958613 0,12536377 ! blood coagulation GO:0007596 116 75 0,000 0,12110339 0,12689649 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 0,000 0,12110339 0,12683871 ! nuclear import GO:0051170 121 75 0,000 0,12110339 0,12678097 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,12110339 0,12672329 ! amine biosynthetic process GO:0009309 97 76 0,000 0,12261812 0,12824997 ! tRNA metabolic process GO:0006399 95 76 0,000 0,12261812 0,12819167 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,12261812 0,12813343 ! regulation of protein transport GO:0051223 114 76 0,000 0,12261812 0,12807524 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,12413033 0,12959589 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,12413033 0,12953709 ! regulation of DNA binding GO:0051101 119 77 0,000 0,12413033 0,12947834 ! gland development GO:0048732 148 77 0,000 0,12413033 0,12941965 ! sex differentiation GO:0007548 105 77 0,000 0,12413033 0,12936101 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,12413033 0,12930242 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,12413033 0,12924389 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,12413033 0,12918541 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,12564001 0,13069743 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,12564001 0,13063835 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,12714718 0,13214574 ! cellular respiration GO:0045333 107 79 0,000 0,12714718 0,13208605 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,12714718 0,13202642 ! T cell activation GO:0042110 134 79 0,000 0,12714718 0,13196684 ! regulation of lyase activity GO:0051339 133 79 0,000 0,12714718 0,13190732 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,12714718 0,13184785 ! chromatin assembly GO:0031497 102 80 0,000 0,12865184 0,13334801 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,12865184 0,13328794 ! protein localization in nucleus GO:0034504 133 80 0,000 0,12865184 0,13322793 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,12865184 0,13316797 ! forebrain development GO:0030900 131 80 0,000 0,12865184 0,13310807 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,13015399 0,1346017 ! hemostasis GO:0007599 125 81 0,000 0,13015399 0,13454121 ! mRNA transport GO:0051028 121 81 0,000 0,13015399 0,13448077 ! regulation of neurological system process GO:0031644 122 81 0,000 0,13015399 0,13442038 ! vitamin metabolic process GO:0006766 103 81 0,000 0,13015399 0,13436005 ! ossification GO:0001503 134 82 0,000 0,13165364 0,13584719 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,13165364 0,13578627 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,13315079 0,13726886 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,13315079 0,13720736 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,13315079 0,13714591 ! regulation of defense response GO:0031347 117 84 0,000 0,13464544 0,13862333 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,13464544 0,13856131 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,13464544 0,13849934 ! sterol metabolic process GO:0016125 120 84 0,000 0,13464544 0,13843743 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,13613761 0,13990907 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,13613761 0,13984658 ! rRNA metabolic process GO:0016072 107 85 0,000 0,13613761 0,13978415 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,13613761 0,13972177 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,13613761 0,13965945 ! regulation of protein localization GO:0032880 132 85 0,000 0,13613761 0,13959719 ! regulation of membrane potential GO:0042391 128 85 0,000 0,13613761 0,13953498 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,13613761 0,13947283 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,13762728 0,14093622 ! nucleosome organization GO:0034728 114 87 0,000 0,13911447 0,14239577 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,13911447 0,14233242 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,13911447 0,14226914 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,13911447 0,14220591 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,13911447 0,14214273 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,13911447 0,14207961 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,14059918 0,14353223 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,14059918 0,14346856 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,14059918 0,14340493 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,14059918 0,14334137 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,14059918 0,14327786 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,14208142 0,14472421 ! reproductive developmental process GO:0003006 127 89 0,000 0,14208142 0,14466015 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,14208142 0,14459614 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,14208142 0,14453218 ! regulation of T cell activation GO:0050863 128 89 0,000 0,14208142 0,14446829 ! leukocyte differentiation GO:0002521 143 90 0,000 0,14356119 0,14590841 ! hormone metabolic process GO:0042445 121 90 0,000 0,14356119 0,14584396 ! RNA localization GO:0006403 135 91 0,000 0,14503848 0,1472797 ! ATP metabolic process GO:0046034 137 91 0,000 0,14503848 0,1472147 ! response to virus GO:0009615 122 91 0,000 0,14503848 0,14714976 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,14651332 0,14858053 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,14651332 0,14851504 ! cell fate commitment GO:0045165 141 92 0,000 0,14651332 0,14844962 ! positive regulation of immune response GO:0050778 121 92 0,000 0,14651332 0,14838425 ! DNA recombination GO:0006310 146 92 0,000 0,14651332 0,14831894 ! sulfur metabolic process GO:0006790 118 92 0,000 0,14651332 0,14825369 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,14798569 0,1496777 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,14798569 0,14961191 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,14798569 0,14954618 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,14798569 0,1494805 ! electron transport chain GO:0022900 123 94 0,000 0,14945561 0,150899 ! response to oxidative stress GO:0006979 141 94 0,000 0,14945561 0,15083278 ! regulation of binding GO:0051098 151 95 0,000 0,15092308 0,15224697 ! angiogenesis GO:0001525 149 95 0,000 0,15092308 0,15218022 ! carboxylic acid transport GO:0046942 147 95 0,000 0,15092308 0,15211353 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,1523881 0,15352284 ! in utero embryonic development GO:0001701 147 96 0,000 0,1523881 0,15345562 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,1523881 0,15338846 ! protein maturation GO:0051604 129 96 0,000 0,1523881 0,15332136 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,15385068 0,15472521 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,15385068 0,15465759 ! calcium ion transport GO:0006816 167 99 0,000 0,15676852 0,15752188 ! extracellular structure organization GO:0043062 156 99 0,000 0,15676852 0,15745309 ! protein import GO:0017038 156 99 0,000 0,15676852 0,15738437 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,15676852 0,1573157 ! regulation of translation GO:0006417 151 100 0,000 0,15822379 0,15870681 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,15822379 0,15863762 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,15822379 0,1585685 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,15822379 0,15849944 ! divalent metal ion transport GO:0070838 171 100 0,000 0,15822379 0,15843043 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,15822379 0,15836149 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,15822379 0,15829261 ! protein localization in organelle GO:0033365 161 100 0,000 0,15822379 0,15822379