pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/2671-3-real-Loi_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 2,864E-09 6,892E-06 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 1,298E-07 1,561E-04 ! interphase GO:0051325 213 98 4,000 1,517E-07 1,217E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 3,384E-07 2,035E-04 ! negative regulation of caspase activity GO:0043154 22 14 2,000 6,681E-07 3,215E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 8,11E-07 3,252E-04 ! axon cargo transport GO:0008088 43 16 2,000 1,026E-06 3,527E-04 ! negative regulation of peptidase activity GO:0010466 27 17 2,000 1,245E-06 3,744E-04 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 1,559E-06 4,169E-04 ! negative regulation of kinase activity GO:0033673 131 68 3,000 1,655E-06 3,983E-04 ! negative regulation of transferase activity GO:0051348 140 72 3,000 2,084E-06 4,558E-04 ! microtubule-based transport GO:0010970 54 22 2,000 2,807E-06 5,628E-04 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 4,181E-06 7,738E-04 ! negative regulation of hydrolase activity GO:0051346 62 35 2,000 1,179E-05 2,027E-03 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 1,546E-05 2,481E-03 ! regulation of retroviral genome replication GO:0045091 7 5 1,000 1,546E-05 2,325E-03 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 2,000 2,056E-05 2,91E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 3,082E-05 4,119E-03 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 1,000 3,242E-05 4,106E-03 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 3,242E-05 3,901E-03 ! spindle checkpoint GO:0031577 15 7 1,000 3,242E-05 3,715E-03 ! response to UV GO:0009411 104 53 2,000 4,156E-05 4,545E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 4,32E-05 4,519E-03 ! DNA topological change GO:0006265 12 8 1,000 4,32E-05 4,331E-03 ! establishment of chromosome localization GO:0051303 12 8 1,000 4,32E-05 4,157E-03 GO:0050000|chromosome localization, ! keratinocyte proliferation GO:0043616 14 9 1,000 5,55E-05 5,135E-03 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 1,000 5,55E-05 4,945E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 6,931E-05 5,956E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 6,931E-05 5,751E-03 ! DNA ligation GO:0006266 19 10 1,000 6,931E-05 5,559E-03 ! positive regulation of viral reproduction GO:0048524 18 10 1,000 6,931E-05 5,38E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,015E-04 7,631E-03 ! positive regulation of cell growth GO:0030307 22 12 1,000 1,015E-04 7,4E-03 ! regulation of exit from mitosis GO:0007096 17 12 1,000 1,015E-04 7,183E-03 ! regulation of caspase activity GO:0043281 122 72 2,000 1,041E-04 7,154E-03 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 1,129E-04 7,547E-03 ! regulation of peptidase activity GO:0052547 134 79 2,000 1,372E-04 8,919E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 1,397E-04 8,847E-03 ! positive regulation of cell size GO:0045793 27 15 1,000 1,611E-04 9,938E-03 ! regulation of viral genome replication GO:0045069 28 17 1,000 2,083E-04 0,01253025 ! skin development GO:0043588 36 19 1,000 2,615E-04 0,01534622 ! cellular response to unfolded protein GO:0034620 33 19 1,000 2,615E-04 0,01498084 GO:0030968|endoplasmic reticulum unfolded protein response, ! cell cycle arrest GO:0007050 213 100 2,000 2,754E-04 0,01540823 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 2,903E-04 0,01587612 ! inactivation of MAPK activity GO:0000188 39 21 1,000 3,206E-04 0,0171437 ! apoptotic nuclear changes GO:0030262 32 22 1,000 3,524E-04 0,01843343 ! positive regulation of B cell activation GO:0050871 38 22 1,000 3,524E-04 0,01804123 ! regulation of viral reproduction GO:0050792 38 23 1,000 3,857E-04 0,01933239 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 4,204E-04 0,02064303 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 4,204E-04 0,02023017 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 4,566E-04 0,021541 ! chromosome condensation GO:0030261 45 25 1,000 4,566E-04 0,02112675 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 4,566E-04 0,02072813 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 4,943E-04 0,0220221 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of nuclear division GO:0051785 40 26 1,000 4,943E-04 0,0216217 GO:0045840|positive regulation of mitosis, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 5,334E-04 0,0229162 ! fat cell differentiation GO:0045444 50 27 1,000 5,334E-04 0,02251416 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 5,74E-04 0,02380903 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 6,16E-04 0,02511924 ! regulation of B cell activation GO:0050864 50 30 1,000 6,594E-04 0,02644386 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 7,507E-04 0,02961063 ! nucleus organization GO:0006997 67 38 1,000 1,059E-03 0,04109482 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 1,059E-03 0,04044252 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! cytokinesis GO:0000910 72 40 1,000 1,173E-03 0,0441009 ! keratinocyte differentiation GO:0030216 62 41 1,000 1,232E-03 0,04561294 ! epidermal cell differentiation GO:0009913 68 46 1,000 1,549E-03 0,05647525 ! response to calcium ion GO:0051592 81 47 1,000 1,617E-03 0,05805873 ! JNK cascade GO:0007254 91 47 1,000 1,617E-03 0,05720492 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 1,686E-03 0,05878027 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 1,756E-03 0,06035813 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 1,901E-03 0,0644152 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 1,901E-03 0,06352054 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of growth GO:0045927 90 52 1,000 1,975E-03 0,06510468 ! RNA elongation GO:0006354 79 55 1,000 2,207E-03 0,07175489 ! positive regulation of organelle organization GO:0010638 100 56 1,000 2,287E-03 0,07336204 ! establishment of organelle localization GO:0051656 109 59 1,000 2,535E-03 0,08024425 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 2,62E-03 0,08186821 ! regulation of mitosis GO:0007088 105 63 1,000 2,884E-03 0,08896236 GO:0051783|regulation of nuclear division, ! negative regulation of cell growth GO:0030308 132 67 1,000 3,255E-03 0,09912469 ! chromosome segregation GO:0007059 113 67 1,000 3,255E-03 0,09788563 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 3,351E-03 0,09952779 ! cell cycle checkpoint GO:0000075 137 69 1,000 3,448E-03 0,1011685 ! negative regulation of cell size GO:0045792 134 69 1,000 3,448E-03 0,0999496 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 3,448E-03 0,09875972 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 3,748E-03 0,1060815 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 3,748E-03 0,104848 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 3,748E-03 0,10364285 ! organelle localization GO:0051640 136 74 1,000 3,954E-03 0,10810626 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 4,059E-03 0,10973308 ! positive regulation of ligase activity GO:0051351 124 77 1,000 4,273E-03 0,11423726 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 4,273E-03 0,1129819 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 4,382E-03 0,11460384 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 4,492E-03 0,1162241 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 4,492E-03 0,11498767 ! response to metal ion GO:0010038 140 80 1,000 4,604E-03 0,11660218 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 4,717E-03 0,11821505 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of growth GO:0045926 155 84 1,000 5,063E-03 0,1255805 ! regulation of ligase activity GO:0051340 142 84 1,000 5,063E-03 0,12429907 ! response to unfolded protein GO:0006986 131 85 1,000 5,181E-03 0,12590863 ! positive regulation of cell activation GO:0050867 145 85 1,000 5,181E-03 0,12464954 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 5,3E-03 0,12625379 ! mitochondrion organization GO:0007005 148 86 1,000 5,3E-03 0,12501601 ! positive regulation of protein modification process GO:0031401 136 88 1,000 5,542E-03 0,12945686 ! regulation of cell cycle process GO:0010564 149 90 1,000 5,789E-03 0,13392807 ! response to protein stimulus GO:0051789 149 91 1,000 5,914E-03 0,13552615 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 6,169E-03 0,14002501 GO:0010498|proteasomal protein catabolic process, ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 6,293E-03 0,14150982 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 6,293E-03 0,14019954 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 6,293E-03 0,13891331 ! positive regulation of helicase activity GO:0051096 11 5 0,000 6,293E-03 0,13765046 ! neuron fate determination GO:0048664 7 5 0,000 6,293E-03 0,13641036 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,293E-03 0,13519241 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 6,293E-03 0,13399602 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 6,293E-03 0,13282062 ! polyol transport GO:0015791 12 5 0,000 6,293E-03 0,13166566 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 6,293E-03 0,13053061 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 6,293E-03 0,12941496 ! response to superoxide GO:0000303 10 5 0,000 6,293E-03 0,12831822 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,293E-03 0,12723992 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 6,293E-03 0,12617959 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 6,293E-03 0,12513678 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 6,293E-03 0,12411107 ! female meiosis GO:0007143 7 5 0,000 6,293E-03 0,12310204 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 6,293E-03 0,12210928 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 6,293E-03 0,1211324 ! cobalt ion transport GO:0006824 11 5 0,000 6,293E-03 0,12017103 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 6,293E-03 0,11922481 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 6,293E-03 0,11829336 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 6,293E-03 0,11737636 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 6,293E-03 0,11647346 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 6,293E-03 0,11558435 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 6,293E-03 0,11470872 ! embryonic camera-type eye development GO:0031076 10 5 0,000 6,293E-03 0,11384624 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 6,293E-03 0,11299664 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 6,293E-03 0,11215963 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 6,293E-03 0,11133493 ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,293E-03 0,11052227 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 6,293E-03 0,10972138 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 6,293E-03 0,10893202 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 6,293E-03 0,10815393 ! negative chemotaxis GO:0050919 14 5 0,000 6,293E-03 0,10738688 ! positive regulation of histone modification GO:0031058 5 5 0,000 6,293E-03 0,10663064 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,293E-03 0,10588497 ! sensory perception of bitter taste GO:0050913 7 5 0,000 6,293E-03 0,10514966 ! behavioral response to pain GO:0048266 9 5 0,000 6,293E-03 0,10442449 ! clathrin coat assembly GO:0048268 14 5 0,000 6,293E-03 0,10370925 ! Notch receptor processing GO:0007220 8 5 0,000 6,293E-03 0,10300374 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,293E-03 0,10230777 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 6,293E-03 0,10162114 ! micturition GO:0060073 9 5 0,000 6,293E-03 0,10094367 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 6,293E-03 0,10027517 ! copulation GO:0007620 9 5 0,000 6,293E-03 0,09961546 ! glial cell fate commitment GO:0021781 13 5 0,000 6,293E-03 0,09896438 ! protein maturation by protein folding GO:0022417 13 5 0,000 6,293E-03 0,09832176 ! spermidine metabolic process GO:0008216 7 5 0,000 6,293E-03 0,09768742 ! regulation of potassium ion transport GO:0043266 10 5 0,000 6,293E-03 0,09706122 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 6,293E-03 0,096443 ! apoptotic cell clearance GO:0043277 20 5 0,000 6,293E-03 0,0958326 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 6,293E-03 0,09522988 ! lipoprotein particle clearance GO:0034381 10 5 0,000 6,293E-03 0,09463469 ! grooming behavior GO:0007625 6 5 0,000 6,293E-03 0,0940469 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 6,293E-03 0,09346636 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 6,293E-03 0,09289295 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,293E-03 0,09232653 ! response to protozoan GO:0001562 10 5 0,000 6,293E-03 0,09176697 ! positive regulation of glycolysis GO:0045821 14 5 0,000 6,293E-03 0,09121416 ! lymph vessel development GO:0001945 10 5 0,000 6,293E-03 0,09066797 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 6,293E-03 0,09012828 ! endochondral ossification GO:0001958 16 5 0,000 6,293E-03 0,08959497 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 6,293E-03 0,08906794 ! parathyroid gland development GO:0060017 13 5 0,000 6,293E-03 0,08854708 ! anagen GO:0042640 6 5 0,000 6,293E-03 0,08803227 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 6,293E-03 0,08752341 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 6,293E-03 0,0870204 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 6,293E-03 0,08652315 ! dorsal spinal cord development GO:0021516 7 5 0,000 6,293E-03 0,08603154 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 6,293E-03 0,08554548 ! sphingoid catabolic process GO:0046521 6 5 0,000 6,293E-03 0,08506489 ! skeletal myofibril assembly GO:0014866 10 5 0,000 6,293E-03 0,08458967 ! smooth muscle tissue development GO:0048745 28 5 0,000 6,293E-03 0,08411972 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,293E-03 0,08365497 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 6,293E-03 0,08319533 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 6,293E-03 0,08274071 ! cardiac muscle fiber development GO:0048739 10 5 0,000 6,293E-03 0,08229103 ! transepithelial chloride transport GO:0030321 9 5 0,000 6,293E-03 0,08184622 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,293E-03 0,08140618 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 6,293E-03 0,08097086 ! neutrophil mediated immunity GO:0002446 7 5 0,000 6,293E-03 0,08054016 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 6,293E-03 0,08011402 ! histidine catabolic process GO:0006548 6 5 0,000 6,293E-03 0,07969237 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 6,293E-03 0,07927513 ! microvillus organization GO:0032528 7 5 0,000 6,293E-03 0,07886224 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 6,293E-03 0,07845363 ! L-serine biosynthetic process GO:0006564 6 5 0,000 6,293E-03 0,07804923 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 6,293E-03 0,07764898 ! tryptophan metabolic process GO:0006568 9 5 0,000 6,293E-03 0,07725281 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 6,293E-03 0,07686066 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 6,293E-03 0,07647248 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 6,293E-03 0,07608819 ! polyol catabolic process GO:0046174 7 5 0,000 6,293E-03 0,07570775 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 6,293E-03 0,0753311 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 6,293E-03 0,07495817 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 6,293E-03 0,07458892 ! muscle cell migration GO:0014812 8 5 0,000 6,293E-03 0,07422329 ! mitochondrial fission GO:0000266 8 5 0,000 6,293E-03 0,07386122 ! sister chromatid cohesion GO:0007062 12 5 0,000 6,293E-03 0,07350267 ! mRNA transcription GO:0009299 9 5 0,000 6,293E-03 0,07314759 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 6,293E-03 0,07279592 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 6,293E-03 0,07244761 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 6,293E-03 0,07210262 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 6,293E-03 0,0717609 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 6,293E-03 0,07142241 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 6,293E-03 0,07108709 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 6,293E-03 0,07075491 ! response to food GO:0032094 6 5 0,000 6,293E-03 0,07042582 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 6,293E-03 0,07009977 ! positive regulation of transporter activity GO:0032411 8 5 0,000 6,293E-03 0,06977673 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 6,293E-03 0,06945665 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,293E-03 0,0691395 ! paraxial mesoderm development GO:0048339 14 5 0,000 6,293E-03 0,06882523 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 6,293E-03 0,0685138 ! forebrain neuron development GO:0021884 13 5 0,000 6,293E-03 0,06820518 ! lipoprotein catabolic process GO:0042159 11 5 0,000 6,293E-03 0,06789933 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 6,293E-03 0,06759621 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 6,293E-03 0,06729578 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,293E-03 0,06699801 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 6,293E-03 0,06670287 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 6,293E-03 0,06641031 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,293E-03 0,06612031 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 6,293E-03 0,06583283 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 6,293E-03 0,06554784 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 6,293E-03 0,0652653 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 6,293E-03 0,06498519 ! basic amino acid transport GO:0015802 11 5 0,000 6,293E-03 0,06470748 ! cellular glucose homeostasis GO:0001678 5 5 0,000 6,293E-03 0,06443213 ! early endosome to late endosome transport GO:0045022 12 5 0,000 6,293E-03 0,06415911 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,293E-03 0,0638884 ! depyrimidination GO:0045008 10 5 0,000 6,293E-03 0,06361996 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,293E-03 0,06335377 ! regulation of centrosome cycle GO:0046605 7 5 0,000 6,293E-03 0,06308979 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 6,293E-03 0,06282801 ! zinc ion homeostasis GO:0055069 8 5 0,000 6,293E-03 0,06256839 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 6,293E-03 0,06231091 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 6,293E-03 0,06205553 ! forebrain morphogenesis GO:0048853 13 5 0,000 6,293E-03 0,06180225 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 6,293E-03 0,06155102 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 6,293E-03 0,06130182 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 6,293E-03 0,06105464 ! peptidyl-arginine modification GO:0018195 9 5 0,000 6,293E-03 0,06080944 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,293E-03 0,0605662 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,293E-03 0,0603249 ! response to arsenic GO:0046685 10 5 0,000 6,293E-03 0,06008552 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 6,293E-03 0,05984803 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 6,293E-03 0,0596124 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 6,293E-03 0,05937863 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 6,293E-03 0,05914668 ! response to cadmium ion GO:0046686 7 5 0,000 6,293E-03 0,05891654 ! bile acid biosynthetic process GO:0006699 6 5 0,000 6,293E-03 0,05868818 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 6,293E-03 0,05846158 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 6,293E-03 0,05823673 ! decidualization GO:0046697 11 5 0,000 6,293E-03 0,0580136 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 6,293E-03 0,05779218 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 6,293E-03 0,05757243 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 6,293E-03 0,05735436 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 6,293E-03 0,05713793 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 6,293E-03 0,05692312 ! base conversion or substitution editing GO:0016553 5 5 0,000 6,293E-03 0,05670993 ! neural tube patterning GO:0021532 7 5 0,000 6,293E-03 0,05649832 ! embryonic cleavage GO:0040016 6 5 0,000 6,293E-03 0,05628829 ! peroxisome fission GO:0016559 5 5 0,000 6,293E-03 0,05607982 ! histone demethylation GO:0016577 10 5 0,000 6,293E-03 0,05587288 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 6,293E-03 0,05566746 ! mitotic recombination GO:0006312 9 5 0,000 6,293E-03 0,05546355 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 6,293E-03 0,05526113 ! metaphase plate congression GO:0051310 7 5 0,000 6,293E-03 0,05506018 ! regulation of sterol transport GO:0032371 7 5 0,000 6,293E-03 0,05486069 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 6,293E-03 0,05466264 ! enteric nervous system development GO:0048484 8 5 0,000 6,293E-03 0,05446601 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 6,293E-03 0,05427079 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 6,293E-03 0,05407697 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 6,293E-03 0,05388452 ! muscle cell proliferation GO:0033002 11 5 0,000 6,293E-03 0,05369344 ! skeletal muscle regeneration GO:0043403 8 5 0,000 6,293E-03 0,05350371 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 6,293E-03 0,05331532 ! plasminogen activation GO:0031639 5 5 0,000 6,293E-03 0,05312825 ! B cell homeostasis GO:0001782 13 5 0,000 6,293E-03 0,05294248 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 6,293E-03 0,05275802 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 6,293E-03 0,05257483 ! metaphase GO:0051323 8 5 0,000 6,293E-03 0,05239291 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 6,293E-03 0,05221224 ! cellular response to nutrient GO:0031670 8 5 0,000 6,293E-03 0,05203282 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 6,293E-03 0,05185462 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 6,293E-03 0,05167765 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 6,293E-03 0,05150187 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 6,293E-03 0,05132729 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 6,293E-03 0,05115389 ! response to redox state GO:0051775 5 5 0,000 6,293E-03 0,05098165 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 6,293E-03 0,05081057 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 6,293E-03 0,05064064 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,293E-03 0,05047183 ! regulation of telomerase activity GO:0051972 6 5 0,000 6,293E-03 0,05030415 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,293E-03 0,05013758 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 6,293E-03 0,04997211 ! porphyrin catabolic process GO:0006787 12 5 0,000 6,293E-03 0,04980773 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 6,293E-03 0,04964443 ! striatum development GO:0021756 9 5 0,000 6,293E-03 0,04948219 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 6,293E-03 0,04932101 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 6,293E-03 0,04916088 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 6,293E-03 0,04900178 ! glial cell migration GO:0008347 11 5 0,000 6,293E-03 0,04884371 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,293E-03 0,04868666 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 6,293E-03 0,04853061 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 6,293E-03 0,04837556 ! somatic stem cell maintenance GO:0035019 15 5 0,000 6,293E-03 0,0482215 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 6,293E-03 0,04806841 ! negative regulation of lipase activity GO:0060192 8 5 0,000 6,293E-03 0,0479163 ! neuroprotection GO:0043526 6 5 0,000 6,293E-03 0,04776514 ! neural plate development GO:0001840 8 5 0,000 6,293E-03 0,04761494 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 6,293E-03 0,04746568 ! regulation of sensory perception GO:0051931 7 5 0,000 6,293E-03 0,04731734 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 6,293E-03 0,04716994 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 6,293E-03 0,04702345 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 6,293E-03 0,04687787 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 6,293E-03 0,04673318 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 6,293E-03 0,04658939 ! sequestering of calcium ion GO:0051208 7 5 0,000 6,293E-03 0,04644647 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 6,293E-03 0,04630444 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 6,293E-03 0,04616326 ! spindle assembly GO:0051225 6 5 0,000 6,293E-03 0,04602295 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 6,293E-03 0,04588349 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 6,293E-03 0,04574487 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 6,293E-03 0,04560708 ! drug metabolic process GO:0017144 6 5 0,000 6,293E-03 0,04547012 ! stem cell division GO:0017145 11 5 0,000 6,293E-03 0,04533398 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 6,293E-03 0,04519866 ! organ regeneration GO:0031100 7 5 0,000 6,293E-03 0,04506414 ! carnitine metabolic process GO:0009437 7 5 0,000 6,293E-03 0,04493042 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 6,293E-03 0,04479749 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 6,293E-03 0,04466534 ! transcription initiation GO:0006352 153 94 1,000 6,298E-03 0,04456857 ! protein ubiquitination GO:0016567 217 97 1,000 6,693E-03 0,04722305 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 7,547E-03 0,05309563 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 7,547E-03 0,05294084 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 7,547E-03 0,05278694 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 7,547E-03 0,05263393 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 7,547E-03 0,05248181 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 7,547E-03 0,05233057 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 7,547E-03 0,05218019 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 7,547E-03 0,05203068 ! sleep GO:0030431 13 6 0,000 7,547E-03 0,05188202 ! response to oxygen radical GO:0000305 11 6 0,000 7,547E-03 0,05173421 ! positive regulation of axon extension GO:0045773 11 6 0,000 7,547E-03 0,05158724 ! myoblast cell fate commitment GO:0048625 16 6 0,000 7,547E-03 0,0514411 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 7,547E-03 0,05129578 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 7,547E-03 0,05115129 ! regulation of interferon-beta production GO:0032648 8 6 0,000 7,547E-03 0,0510076 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 7,547E-03 0,05086473 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 7,547E-03 0,05072265 ! forebrain regionalization GO:0021871 8 6 0,000 7,547E-03 0,05058136 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 7,547E-03 0,05044085 ! male meiosis GO:0007140 7 6 0,000 7,547E-03 0,05030113 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 7,547E-03 0,05016217 ! response to zinc ion GO:0010043 9 6 0,000 7,547E-03 0,05002399 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 7,547E-03 0,04988656 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 7,547E-03 0,04974988 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 7,547E-03 0,04961395 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 7,547E-03 0,04947877 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 7,547E-03 0,04934431 ! malate metabolic process GO:0006108 11 6 0,000 7,547E-03 0,04921059 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 7,547E-03 0,04907759 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 7,547E-03 0,0489453 ! protein refolding GO:0042026 15 6 0,000 7,547E-03 0,04881373 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 7,547E-03 0,04868286 ! opsonization GO:0008228 8 6 0,000 7,547E-03 0,04855269 ! mating behavior GO:0007617 7 6 0,000 7,547E-03 0,04842322 ! neuron remodeling GO:0016322 15 6 0,000 7,547E-03 0,04829443 ! erythrocyte maturation GO:0043249 7 6 0,000 7,547E-03 0,04816633 ! embryonic hemopoiesis GO:0035162 14 6 0,000 7,547E-03 0,04803891 ! equilibrioception GO:0050957 14 6 0,000 7,547E-03 0,04791216 ! protein amino acid dealkylation GO:0008214 12 6 0,000 7,547E-03 0,04778607 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 7,547E-03 0,04766065 ! photoreceptor cell development GO:0042461 10 6 0,000 7,547E-03 0,04753588 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 7,547E-03 0,04741177 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 7,547E-03 0,0472883 ! response to interferon-gamma GO:0034341 15 6 0,000 7,547E-03 0,04716547 ! toxin metabolic process GO:0009404 11 6 0,000 7,547E-03 0,04704328 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 7,547E-03 0,04692172 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 7,547E-03 0,04680079 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 7,547E-03 0,04668048 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 7,547E-03 0,04656079 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 7,547E-03 0,04644171 ! cGMP-mediated signaling GO:0019934 13 6 0,000 7,547E-03 0,04632323 ! activation of MAPKKK activity GO:0000185 12 6 0,000 7,547E-03 0,04620536 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 7,547E-03 0,04608809 ! thymic T cell selection GO:0045061 12 6 0,000 7,547E-03 0,04597141 ! protein lipoylation GO:0009249 10 6 0,000 7,547E-03 0,04585532 ! cysteine metabolic process GO:0006534 10 6 0,000 7,547E-03 0,04573982 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 7,547E-03 0,04562489 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 7,547E-03 0,04551054 ! glutamate catabolic process GO:0006538 10 6 0,000 7,547E-03 0,04539677 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 7,547E-03 0,04528356 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 7,547E-03 0,04517091 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 7,547E-03 0,04505883 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 7,547E-03 0,04494729 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 7,547E-03 0,04483631 ! hyperosmotic response GO:0006972 9 6 0,000 7,547E-03 0,04472588 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 7,547E-03 0,04461599 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 7,547E-03 0,04450663 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 7,547E-03 0,04439782 ! urea metabolic process GO:0019627 7 6 0,000 7,547E-03 0,04428953 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 7,547E-03 0,04418177 ! neutrophil activation GO:0042119 8 6 0,000 7,547E-03 0,04407453 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 7,547E-03 0,04396781 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 7,547E-03 0,04386161 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 7,547E-03 0,04375592 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 7,547E-03 0,04365074 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 7,547E-03 0,04354606 ! neuron apoptosis GO:0051402 9 6 0,000 7,547E-03 0,04344188 ! nucleoside salvage GO:0043174 9 6 0,000 7,547E-03 0,0433382 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 7,547E-03 0,04323502 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 7,547E-03 0,04313232 ! T cell mediated immunity GO:0002456 16 6 0,000 7,547E-03 0,04303011 ! negative regulation of platelet activation GO:0010544 9 6 0,000 7,547E-03 0,04292839 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 7,547E-03 0,04282714 ! carnitine transport GO:0015879 10 6 0,000 7,547E-03 0,04272637 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 7,547E-03 0,04262607 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,547E-03 0,04252625 ! positive regulation of exocytosis GO:0045921 8 6 0,000 7,547E-03 0,04242689 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 7,547E-03 0,04232799 ! 5S class rRNA transcription GO:0042791 11 6 0,000 7,547E-03 0,04222955 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 7,547E-03 0,04213157 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 7,547E-03 0,04203404 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 7,547E-03 0,04193697 ! sodium ion homeostasis GO:0055078 11 6 0,000 7,547E-03 0,04184034 ! establishment of spindle localization GO:0051293 12 6 0,000 7,547E-03 0,04174415 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 7,547E-03 0,04164841 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 7,547E-03 0,04155311 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 7,547E-03 0,04145824 ! neural nucleus development GO:0048857 14 6 0,000 7,547E-03 0,0413638 ! response to UV-C GO:0010225 11 6 0,000 7,547E-03 0,04126979 ! astrocyte development GO:0014002 15 6 0,000 7,547E-03 0,04117621 ! protein targeting to lysosome GO:0006622 10 6 0,000 7,547E-03 0,04108305 ! purine base biosynthetic process GO:0009113 17 6 0,000 7,547E-03 0,04099031 ! interaction with symbiont GO:0051702 13 6 0,000 7,547E-03 0,04089799 ! regulation of dendrite development GO:0050773 16 6 0,000 7,547E-03 0,04080608 ! skeletal muscle contraction GO:0003009 6 6 0,000 7,547E-03 0,04071459 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 7,547E-03 0,04062351 ! response to copper ion GO:0046688 10 6 0,000 7,547E-03 0,04053283 ! response to exogenous dsRNA GO:0043330 10 6 0,000 7,547E-03 0,04044255 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 7,547E-03 0,04035268 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,547E-03 0,04026321 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 7,547E-03 0,04017413 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 7,547E-03 0,04008545 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 7,547E-03 0,03999715 ! regulation of dopamine secretion GO:0014059 14 6 0,000 7,547E-03 0,03990925 ! nucleoside catabolic process GO:0009164 7 6 0,000 7,547E-03 0,03982173 ! hair follicle maturation GO:0048820 7 6 0,000 7,547E-03 0,03973459 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 7,547E-03 0,03964783 ! Schwann cell development GO:0014044 15 6 0,000 7,547E-03 0,03956145 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 7,547E-03 0,03947545 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 7,547E-03 0,03938982 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 7,547E-03 0,03930456 ! subpallium development GO:0021544 10 6 0,000 7,547E-03 0,03921967 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 7,547E-03 0,03913514 ! histone ubiquitination GO:0016574 8 6 0,000 7,547E-03 0,03905098 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 7,547E-03 0,03896718 ! maintenance of organ identity GO:0048496 9 6 0,000 7,547E-03 0,03888374 ! G2 phase GO:0051319 16 6 0,000 7,547E-03 0,03880066 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 7,547E-03 0,03871793 ! establishment of planar polarity GO:0001736 7 6 0,000 7,547E-03 0,03863555 ! regulation of mast cell activation GO:0033003 12 6 0,000 7,547E-03 0,03855352 ! membrane to membrane docking GO:0022614 14 6 0,000 7,547E-03 0,03847184 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 7,547E-03 0,0383905 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 7,547E-03 0,03830951 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 7,547E-03 0,03822886 ! receptor internalization GO:0031623 10 6 0,000 7,547E-03 0,03814854 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 7,547E-03 0,03806857 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 7,547E-03 0,03798893 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 7,547E-03 0,03790962 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 7,547E-03 0,03783064 ! protein deubiquitination GO:0016579 14 6 0,000 7,547E-03 0,03775199 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 7,547E-03 0,03767367 ! protein destabilization GO:0031648 9 6 0,000 7,547E-03 0,03759567 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 7,547E-03 0,03751799 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 7,547E-03 0,03744063 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 7,547E-03 0,03736359 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 7,547E-03 0,03728687 ! progesterone metabolic process GO:0042448 10 6 0,000 7,547E-03 0,03721047 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 7,547E-03 0,03713437 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 7,547E-03 0,03705859 ! negative regulation of axon extension GO:0030517 21 6 0,000 7,547E-03 0,03698311 ! removal of superoxide radicals GO:0019430 11 6 0,000 7,547E-03 0,03690794 ! triglyceride catabolic process GO:0019433 10 6 0,000 7,547E-03 0,03683308 ! determination of adult lifespan GO:0008340 15 6 0,000 7,547E-03 0,03675852 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 7,547E-03 0,03668426 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 7,547E-03 0,0366103 ! cerebellar cortex formation GO:0021697 8 6 0,000 7,547E-03 0,03653663 ! catecholamine transport GO:0051937 9 6 0,000 7,547E-03 0,03646327 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 7,547E-03 0,03639019 ! sensory cilium assembly GO:0035058 10 6 0,000 7,547E-03 0,03631741 ! organ or tissue specific immune response GO:0002251 7 6 0,000 7,547E-03 0,03624492 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 7,547E-03 0,03617272 ! maternal placenta development GO:0001893 12 6 0,000 7,547E-03 0,03610081 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 7,547E-03 0,03602918 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 7,547E-03 0,03595784 ! negative regulation of B cell activation GO:0050869 13 6 0,000 7,547E-03 0,03588677 ! protein amino acid prenylation GO:0018346 16 6 0,000 7,547E-03 0,03581599 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 7,547E-03 0,03574549 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 7,547E-03 0,03567526 ! positive regulation of coagulation GO:0050820 12 6 0,000 7,547E-03 0,03560531 ! tRNA transcription GO:0009304 14 7 0,000 8,8E-03 0,04143279 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 8,8E-03 0,04135187 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 8,8E-03 0,04127126 ! behavioral response to cocaine GO:0048148 14 7 0,000 8,8E-03 0,04119097 ! regulation of helicase activity GO:0051095 15 7 0,000 8,8E-03 0,04111098 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 8,8E-03 0,04103131 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 8,8E-03 0,04095195 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 8,8E-03 0,04087289 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 8,8E-03 0,04079414 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 8,8E-03 0,04071569 ! prostate gland development GO:0030850 13 7 0,000 8,8E-03 0,04063754 ! nucleotide-sugar transport GO:0015780 12 7 0,000 8,8E-03 0,04055969 ! synaptonemal complex assembly GO:0007130 10 7 0,000 8,8E-03 0,04048213 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 8,8E-03 0,04040488 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 8,8E-03 0,04032792 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 8,8E-03 0,04025125 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 8,8E-03 0,04017487 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 8,8E-03 0,04009878 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 8,8E-03 0,04002298 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 8,8E-03 0,03994746 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 8,8E-03 0,03987223 ! SMAD protein complex assembly GO:0007183 12 7 0,000 8,8E-03 0,03979729 ! glycolipid transport GO:0046836 10 7 0,000 8,8E-03 0,03972262 ! protein amino acid sulfation GO:0006477 10 7 0,000 8,8E-03 0,03964823 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 8,8E-03 0,03957412 ! neuron adhesion GO:0007158 12 7 0,000 8,8E-03 0,03950029 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 8,8E-03 0,03942673 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 8,8E-03 0,03935345 ! actin-myosin filament sliding GO:0033275 11 7 0,000 8,8E-03 0,03928044 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 8,8E-03 0,0392077 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 8,8E-03 0,03913522 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 8,8E-03 0,03906302 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 8,8E-03 0,03899108 ! mRNA stabilization GO:0048255 18 7 0,000 8,8E-03 0,0389194 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 8,8E-03 0,03884799 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 8,8E-03 0,03877684 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 8,8E-03 0,03870595 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 8,8E-03 0,03863532 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 8,8E-03 0,03856495 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 8,8E-03 0,03849483 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 8,8E-03 0,03842497 ! lipoprotein transport GO:0042953 14 7 0,000 8,8E-03 0,03835536 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 8,8E-03 0,038286 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 8,8E-03 0,03821689 ! rhythmic behavior GO:0007622 15 7 0,000 8,8E-03 0,03814803 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 8,8E-03 0,03807942 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 8,8E-03 0,03801105 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 8,8E-03 0,03794293 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 8,8E-03 0,03787506 ! regulation of odontogenesis GO:0042481 13 7 0,000 8,8E-03 0,03780742 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 8,8E-03 0,03774003 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 8,8E-03 0,03767288 ! mechanosensory behavior GO:0007638 14 7 0,000 8,8E-03 0,03760596 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 8,8E-03 0,03753928 ! positive regulation of isotype switching GO:0045830 15 7 0,000 8,8E-03 0,03747284 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 8,8E-03 0,03740664 ! protein-cofactor linkage GO:0018065 13 7 0,000 8,8E-03 0,03734066 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 8,8E-03 0,03727492 ! spinal cord patterning GO:0021511 13 7 0,000 8,8E-03 0,03720941 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 8,8E-03 0,03714413 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 8,8E-03 0,03707908 ! adrenal gland development GO:0030325 17 7 0,000 8,8E-03 0,03701426 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 8,8E-03 0,03694966 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 8,8E-03 0,03688529 ! ovulation GO:0030728 9 7 0,000 8,8E-03 0,03682114 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 8,8E-03 0,03675722 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 8,8E-03 0,03669351 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 8,8E-03 0,03663003 ! microtubule nucleation GO:0007020 20 7 0,000 8,8E-03 0,03656676 ! proline biosynthetic process GO:0006561 10 7 0,000 8,8E-03 0,03650372 ! thyroid hormone generation GO:0006590 13 7 0,000 8,8E-03 0,03644089 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 8,8E-03 0,03637828 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 8,8E-03 0,03631588 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 8,8E-03 0,03625369 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 8,8E-03 0,03619172 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 8,8E-03 0,03612996 ! galactose metabolic process GO:0006012 13 7 0,000 8,8E-03 0,03606841 ! vesicle fusion GO:0006906 17 7 0,000 8,8E-03 0,03600707 ! response to dietary excess GO:0002021 8 7 0,000 8,8E-03 0,03594594 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 8,8E-03 0,03588501 ! intracellular pH reduction GO:0051452 11 7 0,000 8,8E-03 0,03582429 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 8,8E-03 0,03576378 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 8,8E-03 0,03570347 ! organ growth GO:0035265 15 7 0,000 8,8E-03 0,03564336 ! purine salvage GO:0043101 10 7 0,000 8,8E-03 0,03558346 ! nucleoside transport GO:0015858 8 7 0,000 8,8E-03 0,03552375 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 8,8E-03 0,03546425 ! parturition GO:0007567 14 7 0,000 8,8E-03 0,03540494 ! rRNA modification GO:0000154 14 7 0,000 8,8E-03 0,03534584 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 8,8E-03 0,03528693 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 8,8E-03 0,03522821 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 8,8E-03 0,03516969 ! macrophage differentiation GO:0030225 11 7 0,000 8,8E-03 0,03511137 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 8,8E-03 0,03505324 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 8,8E-03 0,0349953 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 8,8E-03 0,03493755 ! hyaluronan metabolic process GO:0030212 8 7 0,000 8,8E-03 0,03487999 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 8,8E-03 0,03482263 ! anterograde axon cargo transport GO:0008089 18 7 0,000 8,8E-03 0,03476545 ! fibrinolysis GO:0042730 10 7 0,000 8,8E-03 0,03470845 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 8,8E-03 0,03465165 ! eating behavior GO:0042755 7 7 0,000 8,8E-03 0,03459503 ! B cell lineage commitment GO:0002326 21 7 0,000 8,8E-03 0,03453859 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 8,8E-03 0,03448234 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 8,8E-03 0,03442627 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 8,8E-03 0,03437038 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 8,8E-03 0,03431468 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 8,8E-03 0,03425915 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 8,8E-03 0,03420381 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 8,8E-03 0,03414864 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 8,8E-03 0,03409365 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 8,8E-03 0,03403884 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 8,8E-03 0,0339842 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 8,8E-03 0,03392974 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 8,8E-03 0,03387545 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 8,8E-03 0,03382134 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 8,8E-03 0,03376739 ! regulation of meiosis GO:0040020 12 7 0,000 8,8E-03 0,03371362 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 8,8E-03 0,03366003 ! T cell lineage commitment GO:0002360 16 7 0,000 8,8E-03 0,0336066 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 8,8E-03 0,03355334 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 8,8E-03 0,03350025 ! oxygen homeostasis GO:0032364 12 7 0,000 8,8E-03 0,03344732 ! transcription termination GO:0006353 13 7 0,000 8,8E-03 0,03339457 ! response to tumor cell GO:0002347 13 7 0,000 8,8E-03 0,03334198 ! regulation of respiratory burst GO:0060263 11 7 0,000 8,8E-03 0,03328955 ! coenzyme A metabolic process GO:0015936 12 7 0,000 8,8E-03 0,03323729 ! anaphase GO:0051322 17 7 0,000 8,8E-03 0,0331852 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 8,8E-03 0,03313326 ! axonal fasciculation GO:0007413 18 7 0,000 8,8E-03 0,03308149 ! negative regulation of nuclear division GO:0051784 14 7 0,000 8,8E-03 0,03302988 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 8,8E-03 0,03297844 ! peptidyl-threonine modification GO:0018210 25 7 0,000 8,8E-03 0,03292715 ! diuresis GO:0030146 12 7 0,000 8,8E-03 0,03287602 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 8,8E-03 0,03282505 ! thiamin metabolic process GO:0006772 7 7 0,000 8,8E-03 0,03277424 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 8,8E-03 0,03272358 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 8,8E-03 0,03267308 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 8,8E-03 0,03262274 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 8,8E-03 0,03257255 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 8,8E-03 0,03252251 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 8,8E-03 0,03247263 ! melanin biosynthetic process GO:0042438 8 7 0,000 8,8E-03 0,0324229 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 8,8E-03 0,03237333 ! dopamine biosynthetic process GO:0042416 18 7 0,000 8,8E-03 0,0323239 ! glycolipid catabolic process GO:0019377 15 7 0,000 8,8E-03 0,03227463 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 8,8E-03 0,0322255 ! lymph node development GO:0048535 10 7 0,000 8,8E-03 0,03217653 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 8,8E-03 0,0321277 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 8,8E-03 0,03207902 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 8,8E-03 0,03203049 ! endosome to lysosome transport GO:0008333 11 7 0,000 8,8E-03 0,03198211 ! protein modification by small protein removal GO:0070646 16 7 0,000 8,8E-03 0,03193387 ! adult feeding behavior GO:0008343 9 7 0,000 8,8E-03 0,03188578 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 8,8E-03 0,03183783 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 8,8E-03 0,03179002 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 8,8E-03 0,03174236 ! muscle adaptation GO:0043500 14 7 0,000 8,8E-03 0,03169484 ! embryonic heart tube development GO:0035050 10 7 0,000 8,8E-03 0,03164747 ! retina homeostasis GO:0001895 12 7 0,000 8,8E-03 0,03160023 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 8,8E-03 0,03155314 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 8,8E-03 0,03150618 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 8,8E-03 0,03145937 ! protein prenylation GO:0018342 18 7 0,000 8,8E-03 0,03141269 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 8,8E-03 0,03136616 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 8,8E-03 0,03131976 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 8,8E-03 0,0312735 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01005067 0,03566652 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01005067 0,03561399 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01005067 0,03556162 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01005067 0,0355094 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01005067 0,03545733 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01005067 0,03540542 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01005067 0,03535366 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01005067 0,03530205 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01005067 0,03525059 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01005067 0,03519928 ! meiotic prophase I GO:0007128 13 8 0,000 0,01005067 0,03514811 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01005067 0,0350971 ! oligopeptide transport GO:0006857 15 8 0,000 0,01005067 0,03504624 ! UTP metabolic process GO:0046051 8 8 0,000 0,01005067 0,03499552 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01005067 0,03494495 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01005067 0,03489452 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01005067 0,03484424 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01005067 0,0347941 ! succinate metabolic process GO:0006105 14 8 0,000 0,01005067 0,03474411 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01005067 0,03469426 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01005067 0,03464456 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01005067 0,034595 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01005067 0,03454557 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01005067 0,03449629 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01005067 0,03444715 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01005067 0,03439815 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01005067 0,03434929 ! reflex GO:0060004 16 8 0,000 0,01005067 0,03430057 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01005067 0,03425199 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01005067 0,03420354 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01005067 0,03415523 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01005067 0,03410706 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01005067 0,03405902 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01005067 0,03401111 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01005067 0,03396335 ! pigment granule organization GO:0048753 16 8 0,000 0,01005067 0,03391571 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01005067 0,03386821 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01005067 0,03382084 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01005067 0,03377361 ! histidine metabolic process GO:0006547 16 8 0,000 0,01005067 0,0337265 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01005067 0,03367953 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01005067 0,03363269 ! glycine catabolic process GO:0006546 13 8 0,000 0,01005067 0,03358598 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01005067 0,03353939 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01005067 0,03349294 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01005067 0,03344661 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01005067 0,03340042 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01005067 0,03335435 ! melanin metabolic process GO:0006582 15 8 0,000 0,01005067 0,03330841 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01005067 0,03326259 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01005067 0,0332169 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01005067 0,03317133 ! macrophage activation GO:0042116 12 8 0,000 0,01005067 0,03312589 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01005067 0,03308058 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01005067 0,03303539 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01005067 0,03299032 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01005067 0,03294537 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01005067 0,03290055 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01005067 0,03285585 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01005067 0,03281127 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01005067 0,03276681 ! osteoblast development GO:0002076 16 8 0,000 0,01005067 0,03272247 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01005067 0,03267825 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01005067 0,03263415 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01005067 0,03259017 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01005067 0,0325463 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01005067 0,03250256 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01005067 0,03245893 ! response to UV-B GO:0010224 16 8 0,000 0,01005067 0,03241542 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01005067 0,03237202 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01005067 0,03232875 ! intermediate filament organization GO:0045109 12 8 0,000 0,01005067 0,03228558 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01005067 0,03224254 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01005067 0,0321996 ! cellular extravasation GO:0045123 12 8 0,000 0,01005067 0,03215679 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01005067 0,03211408 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01005067 0,03207149 ! response to antibiotic GO:0046677 11 8 0,000 0,01005067 0,03202901 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01005067 0,03198664 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01005067 0,03194439 ! response to tropane GO:0014073 15 8 0,000 0,01005067 0,03190225 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01005067 0,03186021 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01005067 0,03181829 ! melanosome transport GO:0032402 13 8 0,000 0,01005067 0,03177648 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,01005067 0,03173478 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01005067 0,03169319 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01005067 0,0316517 ! mast cell activation GO:0045576 14 8 0,000 0,01005067 0,03161033 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01005067 0,03156906 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01005067 0,0315279 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01005067 0,03148685 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01005067 0,03144591 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01005067 0,03140507 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01005067 0,03136434 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01005067 0,03132371 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01005067 0,03128319 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01005067 0,03124277 ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01005067 0,03120245 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01005067 0,03116225 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01005067 0,03112214 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01005067 0,03108214 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01005067 0,03104224 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01005067 0,03100244 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01005067 0,03096274 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01005067 0,03092315 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01005067 0,03088366 ! hormone catabolic process GO:0042447 17 8 0,000 0,01005067 0,03084426 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01005067 0,03080497 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01005067 0,03076578 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01005067 0,03072669 ! ATP catabolic process GO:0006200 11 8 0,000 0,01005067 0,03068769 ! blastocyst growth GO:0001832 19 8 0,000 0,01005067 0,0306488 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01005067 0,03061 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01005067 0,03057131 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01005067 0,03053271 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01005067 0,0304942 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01005067 0,0304558 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01005067 0,03041749 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01005067 0,03037927 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01005067 0,03034116 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01005067 0,03030314 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01005067 0,03026521 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01005067 0,03022738 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01005067 0,03018964 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01005067 0,030152 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01005067 0,03011445 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01005067 0,03007699 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01005067 0,03003963 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01005067 0,03000236 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01130006 0,03369015 ! axon extension GO:0048675 15 9 0,000 0,01130006 0,03364845 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01130006 0,03360686 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01130006 0,03356537 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01130006 0,03352398 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01130006 0,0334827 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01130006 0,03344151 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01130006 0,03340043 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01130006 0,03335945 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01130006 0,03331857 ! phosphate transport GO:0006817 19 9 0,000 0,01130006 0,03327778 ! reproductive behavior GO:0019098 19 9 0,000 0,01130006 0,0332371 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01130006 0,03319652 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01130006 0,03315604 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01130006 0,03311565 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01130006 0,03307537 ! GTP metabolic process GO:0046039 9 9 0,000 0,01130006 0,03303518 ! RNA methylation GO:0001510 15 9 0,000 0,01130006 0,03299509 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01130006 0,03295509 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01130006 0,03291519 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01130006 0,03287539 ! artery development GO:0060840 24 9 0,000 0,01130006 0,03283569 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01130006 0,03279608 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01130006 0,03275657 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01130006 0,03271715 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01130006 0,03267782 ! chemosensory behavior GO:0007635 20 9 0,000 0,01130006 0,0326386 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01130006 0,03259946 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01130006 0,03256042 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01130006 0,03252147 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01130006 0,03248262 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01130006 0,03244385 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01130006 0,03240518 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01130006 0,03236661 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01130006 0,03232812 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01130006 0,03228973 ! protein targeting to ER GO:0045047 22 9 0,000 0,01130006 0,03225142 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01130006 0,03221321 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01130006 0,03217509 ! T cell selection GO:0045058 23 9 0,000 0,01130006 0,03213706 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,01130006 0,03209911 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01130006 0,03206126 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01130006 0,0320235 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01130006 0,03198582 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01130006 0,03194824 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01130006 0,03191074 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01130006 0,03187333 ! mannose metabolic process GO:0006013 13 9 0,000 0,01130006 0,03183601 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01130006 0,03179877 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01130006 0,03176162 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01130006 0,03172456 ! receptor clustering GO:0043113 18 9 0,000 0,01130006 0,03168759 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01130006 0,0316507 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01130006 0,0316139 ! ruffle organization GO:0031529 15 9 0,000 0,01130006 0,03157718 ! retinol metabolic process GO:0042572 18 9 0,000 0,01130006 0,03154055 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01130006 0,031504 ! behavioral fear response GO:0001662 22 9 0,000 0,01130006 0,03146753 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01130006 0,03143116 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01130006 0,03139486 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01130006 0,03135865 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01130006 0,03132252 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01130006 0,03128648 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01130006 0,03125052 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01130006 0,03121464 ! segment specification GO:0007379 13 9 0,000 0,01130006 0,03117884 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01130006 0,03114313 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01130006 0,03110749 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01130006 0,03107194 ! response to amine stimulus GO:0014075 13 9 0,000 0,01130006 0,03103647 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01130006 0,03100108 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01130006 0,03096577 ! erythrocyte development GO:0048821 15 9 0,000 0,01130006 0,03093055 ! gas homeostasis GO:0033483 16 9 0,000 0,01130006 0,0308954 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01130006 0,03086033 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01130006 0,03082534 ! renal water homeostasis GO:0003091 14 9 0,000 0,01130006 0,03079043 ! postreplication repair GO:0006301 22 9 0,000 0,01130006 0,0307556 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01130006 0,03072085 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01130006 0,03068617 ! icosanoid secretion GO:0032309 15 9 0,000 0,01130006 0,03065158 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01130006 0,03061706 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01130006 0,03058262 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01130006 0,03054826 ! regulation of cell division GO:0051302 15 9 0,000 0,01130006 0,03051397 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01130006 0,03047976 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01130006 0,03044563 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01130006 0,03041158 ! sterol catabolic process GO:0016127 11 9 0,000 0,01130006 0,0303776 GO:0006707|cholesterol catabolic process, ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01130006 0,03034369 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01130006 0,03030987 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01130006 0,03027611 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01130006 0,03024244 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01130006 0,03020883 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01130006 0,03017531 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01130006 0,03014185 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01130006 0,03010847 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01130006 0,03007517 ! purine base metabolic process GO:0006144 21 9 0,000 0,01130006 0,03004193 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01130006 0,03000877 ! pigment granule transport GO:0051904 17 9 0,000 0,01130006 0,02997569 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01130006 0,02994268 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01130006 0,02990974 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01130006 0,02987687 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01130006 0,02984407 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01130006 0,02981135 ! mitochondrion localization GO:0051646 15 9 0,000 0,01130006 0,0297787 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01254792 0,03303097 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01254792 0,03299487 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01254792 0,03295885 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01254792 0,0329229 ! synapsis GO:0007129 13 10 0,000 0,01254792 0,03288704 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01254792 0,03285126 ! N-glycan processing GO:0006491 20 10 0,000 0,01254792 0,03281555 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01254792 0,03277992 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01254792 0,03274436 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01254792 0,03270889 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01254792 0,03267349 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01254792 0,03263817 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,01254792 0,03260292 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01254792 0,03256775 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01254792 0,03253265 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01254792 0,03249764 ! androgen metabolic process GO:0008209 17 10 0,000 0,01254792 0,03246269 ! phospholipid efflux GO:0033700 16 10 0,000 0,01254792 0,03242782 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01254792 0,03239303 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01254792 0,03235831 ! lung alveolus development GO:0048286 26 10 0,000 0,01254792 0,03232367 ! pathogenesis GO:0009405 13 10 0,000 0,01254792 0,03228909 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01254792 0,0322546 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01254792 0,03222017 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01254792 0,03218582 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01254792 0,03215155 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01254792 0,03211734 ! endoderm development GO:0007492 16 10 0,000 0,01254792 0,03208321 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01254792 0,03204915 ! arginine catabolic process GO:0006527 13 10 0,000 0,01254792 0,03201517 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01254792 0,03198125 ! proline metabolic process GO:0006560 13 10 0,000 0,01254792 0,03194741 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01254792 0,03191364 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01254792 0,03187994 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01254792 0,03184631 ! V(D)J recombination GO:0033151 28 10 0,000 0,01254792 0,03181275 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01254792 0,03177927 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01254792 0,03174585 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01254792 0,0317125 ! B cell proliferation GO:0042100 18 10 0,000 0,01254792 0,03167923 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01254792 0,03164602 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01254792 0,03161288 ! multicellular organism growth GO:0035264 18 10 0,000 0,01254792 0,03157982 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01254792 0,03154682 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01254792 0,03151389 ! epithelial cell development GO:0002064 20 10 0,000 0,01254792 0,03148103 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01254792 0,03144823 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01254792 0,03141551 ! macroautophagy GO:0016236 17 10 0,000 0,01254792 0,03138285 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01254792 0,03135026 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01254792 0,03131774 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01254792 0,03128529 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01254792 0,0312529 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01254792 0,03122058 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01254792 0,03118833 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01254792 0,03115614 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01254792 0,03112402 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01254792 0,03109197 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01254792 0,03105998 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01254792 0,03102806 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01254792 0,0309962 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01254792 0,03096441 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01254792 0,03093269 ! response to dsRNA GO:0043331 20 10 0,000 0,01254792 0,03090103 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01254792 0,03086943 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01254792 0,0308379 ! melanosome localization GO:0032400 16 10 0,000 0,01254792 0,03080643 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01254792 0,03077503 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01254792 0,03074369 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01254792 0,03071241 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01254792 0,0306812 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01254792 0,03065005 ! mRNA cleavage GO:0006379 17 10 0,000 0,01254792 0,03061897 ! protein sumoylation GO:0016925 15 10 0,000 0,01254792 0,03058795 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01254792 0,03055699 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01254792 0,03052609 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01254792 0,03049526 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01254792 0,03046448 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01254792 0,03043377 ! salivary gland development GO:0007431 27 10 0,000 0,01254792 0,03040313 ! prophase GO:0051324 15 10 0,000 0,01254792 0,03037254 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01254792 0,03034201 ! apical protein localization GO:0045176 15 10 0,000 0,01254792 0,03031155 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01254792 0,03028115 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01254792 0,03025081 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01254792 0,03022052 ! midbrain development GO:0030901 13 10 0,000 0,01254792 0,0301903 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01254792 0,03016014 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01254792 0,03013004 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01254792 0,0301 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01254792 0,03007002 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01254792 0,0300401 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01254792 0,03001024 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01254792 0,02998044 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01254792 0,0299507 ! oocyte development GO:0048599 17 10 0,000 0,01254792 0,02992101 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01254792 0,02989139 ! blastocyst formation GO:0001825 17 10 0,000 0,01254792 0,02986182 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01254792 0,02983232 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01254792 0,02980287 ! activation of innate immune response GO:0002218 12 10 0,000 0,01254792 0,02977347 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01254792 0,02974414 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01254792 0,02971487 ! response to nicotine GO:0035094 20 10 0,000 0,01254792 0,02968565 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01254792 0,02965649 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01254792 0,02962738 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01254792 0,02959834 ! localization within membrane GO:0051668 20 10 0,000 0,01254792 0,02956935 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01379425 0,03247453 ! respiratory burst GO:0045730 17 11 0,000 0,01379425 0,03244278 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01379425 0,0324111 ! neuron fate specification GO:0048665 17 11 0,000 0,01379425 0,03237948 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01379425 0,03234792 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01379425 0,03231642 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01379425 0,03228499 ! thyroid gland development GO:0030878 26 11 0,000 0,01379425 0,03225361 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01379425 0,0322223 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01379425 0,03219104 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01379425 0,03215985 ! response to pain GO:0048265 24 11 0,000 0,01379425 0,03212872 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01379425 0,03209765 ! T cell proliferation GO:0042098 26 11 0,000 0,01379425 0,03206664 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01379425 0,03203568 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01379425 0,03200479 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01379425 0,03197396 ! bone resorption GO:0045453 16 11 0,000 0,01379425 0,03194318 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01379425 0,03191247 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01379425 0,03188181 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01379425 0,03185122 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01379425 0,03182068 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01379425 0,0317902 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01379425 0,03175978 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01379425 0,03172941 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01379425 0,03169911 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01379425 0,03166886 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01379425 0,03163867 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01379425 0,03160854 ! lipid digestion GO:0044241 18 11 0,000 0,01379425 0,03157847 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01379425 0,03154845 ! UV protection GO:0009650 19 11 0,000 0,01379425 0,03151849 ! adult heart development GO:0007512 14 11 0,000 0,01379425 0,03148858 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01379425 0,03145874 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01379425 0,03142895 ! temperature homeostasis GO:0001659 17 11 0,000 0,01379425 0,03139921 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01379425 0,03136953 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01379425 0,03133991 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01379425 0,03131035 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01379425 0,03128084 ! regulation of organ growth GO:0046620 13 11 0,000 0,01379425 0,03125138 ! pigment granule localization GO:0051875 20 11 0,000 0,01379425 0,03122198 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01379425 0,03119264 ! vasoconstriction GO:0042310 18 11 0,000 0,01379425 0,03116335 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01379425 0,03113412 ! embryonic axis specification GO:0000578 18 11 0,000 0,01379425 0,03110494 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01379425 0,03107581 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01379425 0,03104674 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01379425 0,03101773 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01379425 0,03098876 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01379425 0,03095986 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01379425 0,030931 ! zymogen activation GO:0031638 15 11 0,000 0,01379425 0,0309022 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01379425 0,03087346 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01379425 0,03084477 ! nucleosome positioning GO:0016584 15 11 0,000 0,01379425 0,03081613 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01379425 0,03078754 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01379425 0,03075901 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01379425 0,03073053 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01379425 0,0307021 ! acid secretion GO:0046717 18 11 0,000 0,01379425 0,03067372 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01379425 0,0306454 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01379425 0,03061713 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01379425 0,03058891 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01379425 0,03056074 ! oocyte differentiation GO:0009994 18 11 0,000 0,01379425 0,03053263 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01379425 0,03050457 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01379425 0,03047655 ! cholesterol efflux GO:0033344 19 11 0,000 0,01379425 0,03044859 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01379425 0,03042068 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01379425 0,03039283 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01379425 0,03036502 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01379425 0,03033726 ! embryonic gut development GO:0048566 15 11 0,000 0,01379425 0,03030956 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01379425 0,0302819 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01379425 0,0302543 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01379425 0,03022675 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01379425 0,03019924 ! defense response to fungus GO:0050832 13 11 0,000 0,01379425 0,03017179 ! developmental induction GO:0031128 19 11 0,000 0,01379425 0,03014438 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01379425 0,03011703 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01379425 0,03008973 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01379425 0,03006247 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01379425 0,03003526 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01379425 0,03000811 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01379425 0,029981 ! nucleus localization GO:0051647 19 11 0,000 0,01379425 0,02995394 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01379425 0,02992693 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01503905 0,03259815 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01503905 0,03256881 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01503905 0,03253952 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01503905 0,03251028 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01503905 0,0324811 ! virus-host interaction GO:0019048 29 12 0,000 0,01503905 0,03245197 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01503905 0,03242289 ! cartilage condensation GO:0001502 20 12 0,000 0,01503905 0,03239386 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01503905 0,03236489 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01503905 0,03233597 ! protein complex disassembly GO:0043241 27 12 0,000 0,01503905 0,03230709 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01503905 0,03227827 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01503905 0,03224951 ! hippocampus development GO:0021766 26 12 0,000 0,01503905 0,03222079 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,01503905 0,03219212 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01503905 0,03216351 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01503905 0,03213494 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01503905 0,03210643 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01503905 0,03207797 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01503905 0,03204955 ! drug transport GO:0015893 16 12 0,000 0,01503905 0,03202119 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01503905 0,03199288 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01503905 0,03196462 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01503905 0,0319364 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01503905 0,03190824 ! focal adhesion formation GO:0048041 35 12 0,000 0,01503905 0,03188013 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01503905 0,03185206 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01503905 0,03182405 ! forebrain cell migration GO:0021885 21 12 0,000 0,01503905 0,03179609 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01503905 0,03176817 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01503905 0,0317403 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01503905 0,03171249 ! entry into host cell GO:0030260 32 12 0,000 0,01503905 0,03168472 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01503905 0,031657 ! monoamine transport GO:0015844 18 12 0,000 0,01503905 0,03162932 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01503905 0,0316017 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01503905 0,03157412 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01503905 0,0315466 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01503905 0,03151912 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01503905 0,03149168 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01503905 0,0314643 ! protein homotetramerization GO:0051289 21 12 0,000 0,01503905 0,03143696 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01503905 0,03140968 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01503905 0,03138243 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01503905 0,03135524 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01503905 0,03132809 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01503905 0,03130099 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01503905 0,03127394 ! cranial nerve development GO:0021545 20 12 0,000 0,01503905 0,03124693 ! fucose catabolic process GO:0019317 22 12 0,000 0,01503905 0,03121997 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01503905 0,03119306 ! histone acetylation GO:0016573 26 12 0,000 0,01503905 0,03116619 ! histone methylation GO:0016571 26 12 0,000 0,01503905 0,03113937 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01503905 0,03111259 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01503905 0,03108586 ! gland morphogenesis GO:0022612 29 12 0,000 0,01503905 0,03105918 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01503905 0,03103254 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01503905 0,03100595 ! T cell homeostasis GO:0043029 25 12 0,000 0,01503905 0,03097941 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01503905 0,0309529 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01503905 0,03092645 ! spleen development GO:0048536 22 12 0,000 0,01503905 0,03090004 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01503905 0,03087367 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01503905 0,03084735 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01503905 0,03082108 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01503905 0,03079485 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01503905 0,03076866 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01503905 0,03074252 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01503905 0,03071642 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01503905 0,03069037 ! response to cold GO:0009409 17 12 0,000 0,01503905 0,03066436 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01503905 0,0306384 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01503905 0,03061248 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01628231 0,03311517 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01628231 0,0330872 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01628231 0,03305928 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01628231 0,0330314 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01628231 0,03300357 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01628231 0,03297579 ! lipid localization GO:0010876 28 13 0,000 0,01628231 0,03294806 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01628231 0,03292037 ! organelle fusion GO:0048284 32 13 0,000 0,01628231 0,03289273 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01628231 0,03286514 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01628231 0,03283759 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01628231 0,03281009 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01628231 0,03278263 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01628231 0,03275522 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01628231 0,03272786 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01628231 0,03270054 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01628231 0,03267326 ! methionine metabolic process GO:0006555 27 13 0,000 0,01628231 0,03264604 ! plasma membrane organization GO:0007009 24 13 0,000 0,01628231 0,03261885 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01628231 0,03259172 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01628231 0,03256462 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01628231 0,03253758 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01628231 0,03251058 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01628231 0,03248362 ! response to X-ray GO:0010165 25 13 0,000 0,01628231 0,03245671 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01628231 0,03242984 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01628231 0,03240301 ! exocrine system development GO:0035272 32 13 0,000 0,01628231 0,03237623 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01628231 0,0323495 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01628231 0,03232281 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01628231 0,03229616 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01628231 0,03226956 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01628231 0,032243 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01628231 0,03221648 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01628231 0,03219001 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01628231 0,03216358 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01628231 0,0321372 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01628231 0,03211085 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01628231 0,03208456 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01628231 0,0320583 ! ribosome assembly GO:0042255 17 13 0,000 0,01628231 0,03203209 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01628231 0,03200592 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01628231 0,03197979 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,01628231 0,03195371 ! chromatin silencing GO:0006342 26 13 0,000 0,01628231 0,03192766 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01628231 0,03190166 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01628231 0,03187571 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01628231 0,03184979 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01628231 0,03182392 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01628231 0,03179809 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01628231 0,0317723 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01628231 0,03174655 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01628231 0,03172084 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01628231 0,03169518 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01628231 0,03166956 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01628231 0,03164398 ! embryonic placenta development GO:0001892 23 13 0,000 0,01628231 0,03161844 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01628231 0,03159294 ! insulin secretion GO:0030073 23 13 0,000 0,01628231 0,03156748 ! actin filament polymerization GO:0030041 24 13 0,000 0,01628231 0,03154206 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01628231 0,03151669 ! acrosome reaction GO:0007340 18 13 0,000 0,01628231 0,03149135 ! rRNA transcription GO:0009303 25 14 0,000 0,01752405 0,03386575 ! lactation GO:0007595 26 14 0,000 0,01752405 0,03383857 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01752405 0,03381144 ! reproductive cellular process GO:0048610 20 14 0,000 0,01752405 0,03378435 ! tRNA modification GO:0006400 20 14 0,000 0,01752405 0,0337573 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01752405 0,03373029 ! regulation of S phase GO:0033261 23 14 0,000 0,01752405 0,03370333 ! water transport GO:0006833 21 14 0,000 0,01752405 0,03367641 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01752405 0,03364953 ! non-recombinational repair GO:0000726 25 14 0,000 0,01752405 0,0336227 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,01752405 0,03359591 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01752405 0,03356916 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01752405 0,03354245 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01752405 0,03351579 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01752405 0,03348917 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01752405 0,03346259 ! palate development GO:0060021 31 14 0,000 0,01752405 0,03343605 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01752405 0,03340956 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01752405 0,03338311 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01752405 0,0333567 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01752405 0,03333033 ! arginine metabolic process GO:0006525 17 14 0,000 0,01752405 0,033304 ! regulation of heart rate GO:0002027 24 14 0,000 0,01752405 0,03327771 ! organic alcohol transport GO:0015850 29 14 0,000 0,01752405 0,03325147 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01752405 0,03322527 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01752405 0,03319911 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01752405 0,03317299 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01752405 0,03314691 ! L-amino acid transport GO:0015807 30 14 0,000 0,01752405 0,03312087 ! bone mineralization GO:0030282 17 14 0,000 0,01752405 0,03309487 ! stem cell development GO:0048864 43 14 0,000 0,01752405 0,03306891 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01752405 0,033043 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01752405 0,03301712 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01752405 0,03299129 ! cerebellum development GO:0021549 21 14 0,000 0,01752405 0,03296549 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01752405 0,03293974 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01752405 0,03291402 ! response to gamma radiation GO:0010332 28 14 0,000 0,01752405 0,03288835 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01752405 0,03286272 ! cofactor transport GO:0051181 26 14 0,000 0,01752405 0,03283712 ! NADP metabolic process GO:0006739 24 14 0,000 0,01752405 0,03281157 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01752405 0,03278605 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01752405 0,03276058 ! intestinal absorption GO:0050892 25 14 0,000 0,01752405 0,03273514 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01752405 0,03270975 ! oxygen transport GO:0015671 21 14 0,000 0,01752405 0,03268439 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01752405 0,03265907 ! male genitalia development GO:0030539 24 14 0,000 0,01752405 0,0326338 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01752405 0,03260856 ! regulation of axon extension GO:0030516 37 14 0,000 0,01752405 0,03258336 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01752405 0,0325582 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01876426 0,0348355 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01876426 0,03480865 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,01876426 0,03478183 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01876426 0,03475505 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01876426 0,03472832 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01876426 0,03470162 ! copper ion transport GO:0006825 20 15 0,000 0,01876426 0,03467497 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01876426 0,03464836 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01876426 0,03462179 ! sulfate transport GO:0008272 23 15 0,000 0,01876426 0,03459526 ! response to cAMP GO:0051591 22 15 0,000 0,01876426 0,03456877 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01876426 0,03454232 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01876426 0,03451591 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01876426 0,03448954 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01876426 0,03446322 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01876426 0,03443693 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01876426 0,03441068 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01876426 0,03438447 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01876426 0,03435831 ! pituitary gland development GO:0021983 29 15 0,000 0,01876426 0,03433218 ! vesicle coating GO:0006901 33 15 0,000 0,01876426 0,03430609 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01876426 0,03428004 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01876426 0,03425403 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01876426 0,03422806 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01876426 0,03420213 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01876426 0,03417624 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01876426 0,03415039 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01876426 0,03412458 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01876426 0,0340988 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01876426 0,03407307 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01876426 0,03404737 ! histone deacetylation GO:0016575 20 15 0,000 0,01876426 0,03402171 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01876426 0,03399609 ! tissue regeneration GO:0042246 26 15 0,000 0,01876426 0,03397051 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01876426 0,03394497 ! water homeostasis GO:0030104 27 15 0,000 0,01876426 0,03391947 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01876426 0,033894 ! muscle maintenance GO:0046716 26 15 0,000 0,01876426 0,03386858 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01876426 0,03384319 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01876426 0,03381784 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01876426 0,03379252 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01876426 0,03376725 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01876426 0,03374201 ! cell killing GO:0001906 29 15 0,000 0,01876426 0,03371681 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,01876426 0,03369165 ! detection of bacterium GO:0016045 18 15 0,000 0,01876426 0,03366653 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01876426 0,03364144 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01876426 0,03361639 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01876426 0,03359138 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01876426 0,0335664 ! peptide hormone processing GO:0016486 23 15 0,000 0,01876426 0,03354147 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,02000295 0,0357291 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02000295 0,03570259 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,02000295 0,03567613 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02000295 0,0356497 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,02000295 0,03562331 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02000295 0,03559696 ! bone remodeling GO:0046849 27 16 0,000 0,02000295 0,03557065 ! filopodium assembly GO:0046847 32 16 0,000 0,02000295 0,03554438 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02000295 0,03551815 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02000295 0,03549196 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02000295 0,0354658 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02000295 0,03543969 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,02000295 0,03541361 ! startle response GO:0001964 28 16 0,000 0,02000295 0,03538757 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02000295 0,03536157 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,02000295 0,0353356 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02000295 0,03530968 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,02000295 0,03528379 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02000295 0,03525794 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,02000295 0,03523213 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02000295 0,03520636 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02000295 0,03518062 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,02000295 0,03515493 ! response to osmotic stress GO:0006970 25 16 0,000 0,02000295 0,03512927 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,02000295 0,03510364 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,02000295 0,03507806 ! fructose metabolic process GO:0006000 25 16 0,000 0,02000295 0,03505251 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02000295 0,035027 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02000295 0,03500152 ! intermediate filament-based process GO:0045103 32 16 0,000 0,02000295 0,03497609 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,02000295 0,03495069 ! negative regulation of immune response GO:0050777 35 16 0,000 0,02000295 0,03492532 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02000295 0,0349 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02000295 0,03487471 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,02000295 0,03484945 ! DNA replication initiation GO:0006270 27 16 0,000 0,02000295 0,03482424 ! neuron recognition GO:0008038 35 16 0,000 0,02000295 0,03479906 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02000295 0,03477391 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02000295 0,0347488 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02000295 0,03472373 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,02000295 0,0346987 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,02000295 0,0346737 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02000295 0,03464874 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,02000295 0,03462381 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02000295 0,03459892 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02000295 0,03457406 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02000295 0,03454924 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02000295 0,03452446 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02000295 0,03449971 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02000295 0,034475 ! defense response to virus GO:0051607 37 16 0,000 0,02000295 0,03445032 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,02124011 0,03655487 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,02124011 0,03652874 ! metencephalon development GO:0022037 30 17 0,000 0,02124011 0,03650265 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,02124011 0,0364766 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,02124011 0,03645058 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,02124011 0,0364246 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,02124011 0,03639866 ! signal complex assembly GO:0007172 41 17 0,000 0,02124011 0,03637275 ! endothelial cell migration GO:0043542 28 17 0,000 0,02124011 0,03634688 ! inositol metabolic process GO:0006020 28 17 0,000 0,02124011 0,03632105 ! gene silencing by RNA GO:0031047 36 17 0,000 0,02124011 0,03629525 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,02124011 0,03626949 ! glial cell development GO:0021782 27 17 0,000 0,02124011 0,03624377 ! limbic system development GO:0021761 36 17 0,000 0,02124011 0,03621808 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,02124011 0,03619243 ! adult walking behavior GO:0007628 33 17 0,000 0,02124011 0,03616682 ! heart looping GO:0001947 30 17 0,000 0,02124011 0,03614124 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,02124011 0,0361157 ! myoblast differentiation GO:0045445 45 17 0,000 0,02124011 0,03609019 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,02124011 0,03606472 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,02124011 0,03603929 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,02124011 0,03601389 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,02124011 0,03598853 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02124011 0,0359632 ! glycine metabolic process GO:0006544 28 17 0,000 0,02124011 0,03593791 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,02124011 0,03591266 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02124011 0,03588744 ! NAD metabolic process GO:0019674 29 17 0,000 0,02124011 0,03586225 ! membrane budding GO:0006900 37 17 0,000 0,02124011 0,0358371 ! DNA integration GO:0015074 29 17 0,000 0,02124011 0,03581199 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,02124011 0,03578691 ! regulation of protein binding GO:0043393 33 17 0,000 0,02124011 0,03576187 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,02124011 0,03573686 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,02124011 0,03571189 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,02124011 0,03568695 ! genitalia development GO:0048806 30 17 0,000 0,02124011 0,03566205 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,02124011 0,03563718 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,02124011 0,03561234 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,02124011 0,03558754 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,02124011 0,03556278 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,02124011 0,03553805 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,02124011 0,03551335 ! steroid catabolic process GO:0006706 31 17 0,000 0,02124011 0,03548869 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,02124011 0,03546406 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,02124011 0,03543947 ! gas transport GO:0015669 25 17 0,000 0,02124011 0,03541491 ! organic cation transport GO:0015695 31 17 0,000 0,02124011 0,03539038 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,02124011 0,03536589 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,02124011 0,03534143 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,02124011 0,03531701 ! microspike assembly GO:0030035 36 17 0,000 0,02124011 0,03529262 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,02124011 0,03526826 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,02124011 0,03524394 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,02247576 0,03726855 ! neuron maturation GO:0042551 42 18 0,000 0,02247576 0,03724289 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,02247576 0,03721725 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,02247576 0,03719166 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,02247576 0,0371661 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,02247576 0,03714057 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,02247576 0,03711508 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,02247576 0,03708962 ! memory GO:0007613 31 18 0,000 0,02247576 0,0370642 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02247576 0,03703882 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,02247576 0,03701346 ! patterning of blood vessels GO:0001569 39 18 0,000 0,02247576 0,03698815 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,02247576 0,03696286 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,02247576 0,03693762 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,02247576 0,0369124 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,02247576 0,03688722 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02247576 0,03686208 ! response to retinoic acid GO:0032526 26 18 0,000 0,02247576 0,03683697 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,02247576 0,03681189 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,02247576 0,03678685 ! response to fungus GO:0009620 21 18 0,000 0,02247576 0,03676184 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,02247576 0,03673687 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,02247576 0,03671193 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,02247576 0,03668702 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,02247576 0,03666215 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,02247576 0,03663731 ! vitamin transport GO:0051180 27 18 0,000 0,02247576 0,03661251 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,02247576 0,03658773 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,02247576 0,036563 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,02247576 0,03653829 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,02247576 0,03651362 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,02247576 0,03648898 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,02247576 0,03646438 ! nerve development GO:0021675 28 18 0,000 0,02247576 0,0364398 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,02247576 0,03641527 ! protein secretion GO:0009306 39 19 0,000 0,02370988 0,03838895 ! positive regulation of translation GO:0045727 30 19 0,000 0,02370988 0,03836313 ! negative regulation of defense response GO:0031348 25 19 0,000 0,02370988 0,03833735 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,02370988 0,0383116 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,02370988 0,03828589 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,02370988 0,03826021 ! lipid phosphorylation GO:0046834 35 19 0,000 0,02370988 0,03823457 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02370988 0,03820896 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,02370988 0,03818338 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,02370988 0,03815784 ! bile acid metabolic process GO:0008206 29 19 0,000 0,02370988 0,03813234 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,02370988 0,03810686 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,02370988 0,03808142 ! cerebral cortex development GO:0021987 36 19 0,000 0,02370988 0,03805602 ! pigmentation during development GO:0048066 41 19 0,000 0,02370988 0,03803065 ! response to vitamin A GO:0033189 27 19 0,000 0,02370988 0,03800531 ! heme metabolic process GO:0042168 36 19 0,000 0,02370988 0,03798001 ! actin filament bundle formation GO:0051017 42 19 0,000 0,02370988 0,03795474 ! neuromuscular junction development GO:0007528 34 19 0,000 0,02370988 0,0379295 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,02370988 0,0379043 ! plasma membrane fusion GO:0045026 28 19 0,000 0,02370988 0,03787913 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,02370988 0,037854 ! peptide cross-linking GO:0018149 37 19 0,000 0,02370988 0,0378289 ! protein export from nucleus GO:0006611 36 19 0,000 0,02370988 0,03780383 ! heart process GO:0003015 30 19 0,000 0,02370988 0,03777879 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,02370988 0,03775379 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,02370988 0,03772882 ! visual learning GO:0008542 36 19 0,000 0,02370988 0,03770388 ! cellular pigmentation GO:0033059 36 19 0,000 0,02370988 0,03767898 ! G1 phase GO:0051318 40 19 0,000 0,02370988 0,03765411 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,02370988 0,03762927 ! cell-cell junction organization GO:0045216 35 19 0,000 0,02370988 0,03760447 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,02370988 0,03757969 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,02370988 0,03755495 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,02370988 0,03753025 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,02370988 0,03750557 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,02370988 0,03748093 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,02370988 0,03745632 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,02370988 0,03743174 ! cilium assembly GO:0042384 37 19 0,000 0,02370988 0,0374072 ! peptide hormone secretion GO:0030072 31 19 0,000 0,02370988 0,03738268 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,02494249 0,03930035 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,02494249 0,03927463 ! positive regulation of ossification GO:0045778 47 20 0,000 0,02494249 0,03924894 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,02494249 0,03922329 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,02494249 0,03919767 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,02494249 0,03917208 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,02494249 0,03914653 ! cAMP metabolic process GO:0046058 36 20 0,000 0,02494249 0,03912101 ! response to vitamin GO:0033273 31 20 0,000 0,02494249 0,03909552 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,02494249 0,03907007 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,02494249 0,03904465 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,02494249 0,03901926 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,02494249 0,03899391 ! response to alkaloid GO:0043279 38 20 0,000 0,02494249 0,03896859 ! retinoid metabolic process GO:0001523 32 20 0,000 0,02494249 0,0389433 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,02494249 0,03891805 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,02494249 0,03889282 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,02494249 0,03886764 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,02494249 0,03884248 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,02494249 0,03881735 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,02494249 0,03879226 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,02494249 0,0387672 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,02494249 0,03874217 ! body fluid secretion GO:0007589 31 20 0,000 0,02494249 0,03871718 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,02494249 0,03869222 ! peptide secretion GO:0002790 35 20 0,000 0,02494249 0,03866729 ! stem cell differentiation GO:0048863 53 20 0,000 0,02494249 0,03864239 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,02494249 0,03861752 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,02494249 0,03859269 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,02494249 0,03856788 ! sensory perception of pain GO:0019233 30 20 0,000 0,02494249 0,03854311 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,02494249 0,03851838 ! diencephalon development GO:0021536 34 20 0,000 0,02494249 0,03849367 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,02494249 0,03846899 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,02494249 0,03844435 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,02494249 0,03841974 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,02494249 0,03839516 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,02494249 0,03837061 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,02494249 0,03834609 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,02494249 0,0383216 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,02494249 0,03829715 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,02494249 0,03827272 ! regulation of glucose import GO:0046324 29 20 0,000 0,02494249 0,03824833 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,02494249 0,03822397 ! actin filament-based movement GO:0030048 43 20 0,000 0,02494249 0,03819964 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,02494249 0,03817534 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,02494249 0,03815107 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,02494249 0,03812683 ! negative regulation of translation GO:0017148 29 20 0,000 0,02494249 0,03810262 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,02494249 0,03807844 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,02494249 0,0380543 ! regulation of cell killing GO:0031341 42 21 0,000 0,02617358 0,03990725 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,02617358 0,03988197 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,02617358 0,03985673 ! hormone secretion GO:0046879 38 21 0,000 0,02617358 0,03983152 ! glycerol metabolic process GO:0006071 34 21 0,000 0,02617358 0,03980634 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,02617358 0,0397812 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,02617358 0,03975608 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,02617358 0,039731 ! axis specification GO:0009798 38 21 0,000 0,02617358 0,03970595 ! ovarian follicle development GO:0001541 35 21 0,000 0,02617358 0,03968093 ! smooth muscle contraction GO:0006939 46 21 0,000 0,02617358 0,03965594 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,02617358 0,03963099 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,02617358 0,03960606 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,02617358 0,03958117 ! cell aging GO:0007569 44 21 0,000 0,02617358 0,0395563 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,02617358 0,03953147 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,02617358 0,03950667 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,02617358 0,0394819 ! cytolysis GO:0019835 24 21 0,000 0,02617358 0,03945717 ! vasodilation GO:0042311 39 21 0,000 0,02617358 0,03943246 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,02617358 0,03940778 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,02617358 0,03938314 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,02617358 0,03935852 ! oogenesis GO:0048477 36 21 0,000 0,02617358 0,03933394 ! DNA modification GO:0006304 34 21 0,000 0,02617358 0,03930939 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,02617358 0,03928486 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,02617358 0,03926037 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,02617358 0,03923591 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,02617358 0,03921148 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,02617358 0,03918708 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,02617358 0,03916271 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,02617358 0,03913837 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,02617358 0,03911406 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,02617358 0,03908978 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,02617358 0,03906553 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,02617358 0,03904131 ! collagen catabolic process GO:0030574 28 21 0,000 0,02617358 0,03901712 ! sperm-egg recognition GO:0035036 21 21 0,000 0,02617358 0,03899296 ! gut development GO:0048565 39 21 0,000 0,02617358 0,03896883 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,02740316 0,04077428 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,02740316 0,04074907 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,02740316 0,04072391 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,02740316 0,04069877 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,02740316 0,04067366 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 40 22 0,000 0,02740316 0,04064858 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,02740316 0,04062354 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,02740316 0,04059852 ! regeneration GO:0031099 41 22 0,000 0,02740316 0,04057354 ! keratinization GO:0031424 28 22 0,000 0,02740316 0,04054859 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,02740316 0,04052367 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,02740316 0,04049877 ! sensory perception of taste GO:0050909 28 22 0,000 0,02740316 0,04047391 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,02740316 0,04044908 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,02740316 0,04042428 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,02740316 0,04039951 ! vacuolar transport GO:0007034 36 22 0,000 0,02740316 0,04037477 ! lysosome organization GO:0007040 41 22 0,000 0,02740316 0,04035006 ! central nervous system neuron development GO:0021954 46 22 0,000 0,02740316 0,04032538 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,02740316 0,04030074 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,02740316 0,04027612 ! fucose metabolic process GO:0006004 39 22 0,000 0,02740316 0,04025153 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,02740316 0,04022697 ! ureteric bud development GO:0001657 43 22 0,000 0,02740316 0,04020244 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,02740316 0,04017794 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,02740316 0,04015347 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,02740316 0,04012903 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,02740316 0,04010462 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,02740316 0,04008025 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,02740316 0,0400559 ! sarcomere organization GO:0045214 30 22 0,000 0,02740316 0,04003157 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,02740316 0,04000728 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,02740316 0,03998302 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,02740316 0,03995879 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,02740316 0,03993459 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,02740316 0,03991041 ! protein stabilization GO:0050821 39 22 0,000 0,02740316 0,03988627 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,02863123 0,04164857 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,02863123 0,0416234 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,02863123 0,04159827 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,02863123 0,04157316 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,02863123 0,04154809 ! gluconeogenesis GO:0006094 33 23 0,000 0,02863123 0,04152305 ! viral genome replication GO:0019079 41 23 0,000 0,02863123 0,04149803 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,02863123 0,04147305 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,02863123 0,04144809 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,02863123 0,04142317 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,02863123 0,04139828 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,02863123 0,04137341 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,02863123 0,04134858 ! visual behavior GO:0007632 42 23 0,000 0,02863123 0,04132377 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,02863123 0,041299 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,02863123 0,04127426 ! response to ethanol GO:0045471 46 23 0,000 0,02863123 0,04124954 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,02863123 0,04122486 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,02863123 0,0412002 ! peroxisome organization GO:0007031 37 23 0,000 0,02863123 0,04117557 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,02863123 0,04115098 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,02863123 0,04112641 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,02863123 0,04110187 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,02863123 0,04107736 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,02863123 0,04105288 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,02863123 0,04102843 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,02863123 0,04100401 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,02863123 0,04097961 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,02863123 0,04095525 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,02863123 0,04093092 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,02863123 0,04090661 ! fatty acid transport GO:0015908 44 23 0,000 0,02863123 0,04088233 ! platelet activation GO:0030168 37 23 0,000 0,02863123 0,04085809 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,02863123 0,04083387 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,02863123 0,04080968 ! hormone transport GO:0009914 40 23 0,000 0,02863123 0,04078551 ! cell-cell recognition GO:0009988 25 23 0,000 0,02863123 0,04076138 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,02863123 0,04073728 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,02863123 0,0407132 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,02863123 0,04068915 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,02863123 0,04066513 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,02863123 0,04064114 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,02985778 0,04235721 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,02985778 0,04233225 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,02985778 0,04230732 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,02985778 0,04228242 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,02985778 0,04225755 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,02985778 0,0422327 ! vesicle docking GO:0048278 47 24 0,000 0,02985778 0,04220789 ! spinal cord development GO:0021510 47 24 0,000 0,02985778 0,04218311 ! vacuole organization GO:0007033 43 24 0,000 0,02985778 0,04215835 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,02985778 0,04213362 ! digestive system process GO:0022600 39 24 0,000 0,02985778 0,04210893 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,02985778 0,04208426 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,02985778 0,04205962 ! regulation of behavior GO:0050795 43 24 0,000 0,02985778 0,04203501 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,02985778 0,04201043 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,02985778 0,04198587 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,02985778 0,04196135 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,02985778 0,04193685 ! membrane depolarization GO:0051899 39 24 0,000 0,02985778 0,04191239 ! pallium development GO:0021543 49 24 0,000 0,02985778 0,04188795 ! pentose metabolic process GO:0019321 35 24 0,000 0,02985778 0,04186354 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,02985778 0,04183916 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,02985778 0,0418148 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,02985778 0,04179048 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,02985778 0,04176618 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,02985778 0,04174191 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,02985778 0,04171767 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,02985778 0,04169346 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,02985778 0,04166927 ! regulation of amine transport GO:0051952 40 24 0,000 0,02985778 0,04164512 ! protein tetramerization GO:0051262 52 24 0,000 0,02985778 0,04162099 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,03108283 0,04330359 ! myelination GO:0042552 45 25 0,000 0,03108283 0,04327853 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,03108283 0,0432535 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,03108283 0,0432285 ! phototransduction GO:0007602 33 25 0,000 0,03108283 0,04320352 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,03108283 0,04317858 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,03108283 0,04315366 ! sperm motility GO:0030317 31 25 0,000 0,03108283 0,04312878 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,03108283 0,04310392 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,03108283 0,04307909 ! receptor metabolic process GO:0043112 46 25 0,000 0,03108283 0,04305429 ! response to starvation GO:0042594 42 25 0,000 0,03108283 0,04302952 ! osteoblast differentiation GO:0001649 60 25 0,000 0,03108283 0,04300477 ! neural crest cell development GO:0014032 54 25 0,000 0,03108283 0,04298006 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,03108283 0,04295537 ! negative regulation of cell development GO:0010721 73 25 0,000 0,03108283 0,04293071 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,03108283 0,04290608 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,03108283 0,04288148 ! interaction with host GO:0051701 62 25 0,000 0,03108283 0,0428569 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,03108283 0,04283236 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,03108283 0,04280784 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,03108283 0,04278335 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,03108283 0,04275889 ! immunoglobulin production GO:0002377 55 25 0,000 0,03108283 0,04273446 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,03108283 0,04271005 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,03108283 0,04268567 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,03108283 0,04266132 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,03108283 0,042637 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,03108283 0,04261271 ! telomere organization GO:0032200 43 25 0,000 0,03108283 0,04258844 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,03108283 0,0425642 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,03108283 0,04253999 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,03230638 0,04418939 ! embryonic pattern specification GO:0009880 44 26 0,000 0,03230638 0,04416429 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,03230638 0,04413921 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,03230638 0,04411416 ! initiation of viral infection GO:0019059 57 26 0,000 0,03230638 0,04408913 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,03230638 0,04406414 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,03230638 0,04403917 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,03230638 0,04401424 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,03230638 0,04398933 ! molting cycle process GO:0022404 50 26 0,000 0,03230638 0,04396445 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,03230638 0,04393959 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,03230638 0,04391477 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,03230638 0,04388997 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,03230638 0,0438652 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,03230638 0,04384046 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,03230638 0,04381575 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,03230638 0,04379107 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,03230638 0,04376641 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,03230638 0,04374178 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,03230638 0,04371718 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,03230638 0,0436926 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,03230638 0,04366806 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,03230638 0,04364354 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,03230638 0,04361905 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,03230638 0,04359458 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,03230638 0,04357015 ! blastocyst development GO:0001824 49 26 0,000 0,03230638 0,04354574 ! leukocyte proliferation GO:0070661 52 26 0,000 0,03230638 0,04352136 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,03230638 0,043497 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,03230638 0,04347267 ! neuron fate commitment GO:0048663 48 27 0,000 0,03352841 0,04509188 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,03352841 0,04506669 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,03352841 0,04504152 ! iron ion transport GO:0006826 59 27 0,000 0,03352841 0,04501639 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,03352841 0,04499128 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,03352841 0,0449662 ! protein amino acid acylation GO:0043543 55 27 0,000 0,03352841 0,04494115 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,03352841 0,04491613 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,03352841 0,04489113 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,03352841 0,04486617 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,03352841 0,04484123 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,03352841 0,04481631 ! autophagy GO:0006914 41 27 0,000 0,03352841 0,04479143 ! male gonad development GO:0008584 44 27 0,000 0,03352841 0,04476657 ! response to toxin GO:0009636 47 27 0,000 0,03352841 0,04474175 ! primary neural tube formation GO:0014020 51 27 0,000 0,03352841 0,04471694 ! base-excision repair GO:0006284 41 27 0,000 0,03352841 0,04469217 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,03352841 0,04466742 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,03352841 0,0446427 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,03352841 0,04461801 ! glutathione metabolic process GO:0006749 39 27 0,000 0,03352841 0,04459335 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,03352841 0,04456871 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,03352841 0,0445441 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,03352841 0,04451952 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,03352841 0,04449496 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,03474895 0,04608929 ! circadian rhythm GO:0007623 50 28 0,000 0,03474895 0,0460639 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,03474895 0,04603853 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,03474895 0,04601319 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,03474895 0,04598789 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,03474895 0,0459626 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,03474895 0,04593735 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,03474895 0,04591212 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,03474895 0,04588692 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,03474895 0,04586175 ! synaptogenesis GO:0007416 42 28 0,000 0,03474895 0,04583661 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,03474895 0,04581149 ! lipid oxidation GO:0034440 43 28 0,000 0,03474895 0,0457864 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,03474895 0,04576134 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,03474895 0,04573631 ! translational initiation GO:0006413 65 29 0,000 0,03596799 0,04731491 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,03596799 0,04728906 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,03596799 0,04726323 ! regulation of pH GO:0006885 43 29 0,000 0,03596799 0,04723743 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,03596799 0,04721166 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,03596799 0,04718592 ! catechol metabolic process GO:0009712 54 29 0,000 0,03596799 0,0471602 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,03596799 0,04713452 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,03596799 0,04710886 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,03596799 0,04708323 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,03596799 0,04705763 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,03596799 0,04703205 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,03596799 0,0470065 ! cell fate determination GO:0001709 60 29 0,000 0,03596799 0,04698098 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,03596799 0,04695549 ! detection of light stimulus GO:0009583 38 29 0,000 0,03596799 0,04693003 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,03596799 0,04690459 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,03596799 0,04687918 ! tissue homeostasis GO:0001894 48 29 0,000 0,03596799 0,0468538 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,03596799 0,04682845 ! phenol metabolic process GO:0018958 55 30 0,000 0,03718552 0,04838743 ! zinc ion transport GO:0006829 45 30 0,000 0,03718552 0,04836128 ! membrane docking GO:0022406 61 30 0,000 0,03718552 0,04833515 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,03718552 0,04830905 ! cell junction assembly GO:0034329 78 30 0,000 0,03718552 0,04828298 ! regulation of innate immune response GO:0045088 51 30 0,000 0,03718552 0,04825694 ! acute-phase response GO:0006953 49 30 0,000 0,03718552 0,04823092 ! myofibril assembly GO:0030239 47 30 0,000 0,03718552 0,04820494 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,03718552 0,04817898 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,03718552 0,04815305 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,03718552 0,04812715 ! phospholipid transport GO:0015914 51 30 0,000 0,03718552 0,04810127 ! ensheathment of neurons GO:0007272 57 30 0,000 0,03718552 0,04807542 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,03718552 0,0480496 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,03718552 0,04802381 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,03718552 0,04799805 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,03718552 0,04797231 ! eye morphogenesis GO:0048592 60 30 0,000 0,03718552 0,0479466 ! response to heat GO:0009408 50 30 0,000 0,03718552 0,04792092 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,03840156 0,04946154 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,03840156 0,04943507 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,03840156 0,04940864 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,03840156 0,04938223 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,03840156 0,04935585 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,03840156 0,0493295 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,03840156 0,04930318 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,03840156 0,04927688 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,03840156 0,04925061 ! ovulation cycle process GO:0022602 49 31 0,000 0,03840156 0,04922438 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,03840156 0,04919816 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,03840156 0,04917198 ! peptide transport GO:0015833 55 31 0,000 0,03840156 0,04914583 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,03840156 0,0491197 ! iron ion homeostasis GO:0055072 54 31 0,000 0,03840156 0,0490936 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,03840156 0,04906753 ! mesoderm formation GO:0001707 69 31 0,000 0,03840156 0,04904148 ! natural killer cell activation GO:0030101 45 31 0,000 0,03840156 0,04901547 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,03840156 0,04898948 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,03840156 0,04896352 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,03840156 0,04893758 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,03840156 0,04891167 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,03840156 0,0488858 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,0396161 0,05040526 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,0396161 0,05037862 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,0396161 0,050352 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,0396161 0,05032542 ! cholesterol transport GO:0030301 56 32 0,000 0,0396161 0,05029886 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,0396161 0,05027233 ! spliceosome assembly GO:0000245 67 32 0,000 0,0396161 0,05024583 ! spindle organization GO:0007051 46 32 0,000 0,0396161 0,05021936 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,0396161 0,05019291 ! metanephros development GO:0001656 74 32 0,000 0,0396161 0,0501665 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,0396161 0,05014011 ! response to ionizing radiation GO:0010212 65 32 0,000 0,0396161 0,05011375 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,0396161 0,05008741 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,0396161 0,0500611 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,0396161 0,05003483 ! muscle cell development GO:0055001 49 32 0,000 0,0396161 0,05000857 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,0396161 0,04998235 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,0396161 0,04995615 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,0396161 0,04992999 ! ovulation cycle GO:0042698 51 32 0,000 0,0396161 0,04990384 ! peripheral nervous system development GO:0007422 64 32 0,000 0,0396161 0,04987773 ! BMP signaling pathway GO:0030509 64 32 0,000 0,0396161 0,04985164 ! hindbrain development GO:0030902 61 32 0,000 0,0396161 0,04982558 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,0396161 0,04979955 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,0396161 0,04977355 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,0396161 0,04974757 ! gene silencing GO:0016458 65 32 0,000 0,0396161 0,04972162 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,04082915 0,05121738 ! post-embryonic development GO:0009791 69 33 0,000 0,04082915 0,05119069 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,04082915 0,05116403 ! protein targeting to membrane GO:0006612 68 33 0,000 0,04082915 0,0511374 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,04082915 0,05111079 ! ceramide metabolic process GO:0006672 64 33 0,000 0,04082915 0,05108421 ! formation of primary germ layer GO:0001704 72 33 0,000 0,04082915 0,05105766 ! cell fate specification GO:0001708 52 33 0,000 0,04082915 0,05103114 ! sterol transport GO:0015918 57 33 0,000 0,04082915 0,05100464 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,04082915 0,05097817 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,04082915 0,05095173 ! adult locomotory behavior GO:0008344 59 33 0,000 0,04082915 0,05092532 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,04082915 0,05089893 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,04082915 0,05087257 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,04204071 0,05235505 ! glial cell differentiation GO:0010001 63 34 0,000 0,04204071 0,05232796 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,04204071 0,0523009 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,04204071 0,05227387 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,04204071 0,05224687 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,04204071 0,0522199 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,04204071 0,05219296 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,04204071 0,05216604 ! mismatch repair GO:0006298 46 34 0,000 0,04204071 0,05213915 ! spermatid development GO:0007286 63 34 0,000 0,04204071 0,05211229 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,04204071 0,05208545 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,04204071 0,05205864 ! placenta development GO:0001890 53 34 0,000 0,04204071 0,05203187 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,04204071 0,05200511 ! regulation of muscle development GO:0048634 70 35 0,000 0,04325078 0,0534745 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,04325078 0,05344703 ! negative regulation of secretion GO:0051048 63 35 0,000 0,04325078 0,05341959 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,04325078 0,05339219 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,04325078 0,0533648 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,04325078 0,05333745 ! odontogenesis GO:0042476 66 35 0,000 0,04325078 0,05331013 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,04325078 0,05328283 ! female gonad development GO:0008585 58 35 0,000 0,04325078 0,05325556 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,04325078 0,05322832 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,04325078 0,05320111 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,04325078 0,05317392 ! cytokine production GO:0001816 59 35 0,000 0,04325078 0,05314677 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,04325078 0,05311964 ! neural tube formation GO:0001841 67 35 0,000 0,04325078 0,05309254 ! vesicle localization GO:0051648 64 35 0,000 0,04325078 0,05306546 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,04445936 0,05452049 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,04445936 0,05449272 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,04445936 0,05446497 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,04445936 0,05443726 ! cell junction organization GO:0034330 86 36 0,000 0,04445936 0,05440957 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,04445936 0,05438191 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,04445936 0,05435427 ! positive regulation of cell development GO:0010720 80 36 0,000 0,04445936 0,05432667 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,04445936 0,05429909 ! regulation of proteolysis GO:0030162 72 36 0,000 0,04445936 0,05427154 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,04445936 0,05424402 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,04445936 0,05421653 ! aerobic respiration GO:0009060 55 36 0,000 0,04445936 0,05418906 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,04445936 0,05416163 ! embryonic organ development GO:0048568 57 36 0,000 0,04445936 0,05413422 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,04445936 0,05410683 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,04445936 0,05407948 ! RNA export from nucleus GO:0006405 56 37 0,000 0,04566645 0,05551969 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,04566645 0,05549165 ! meiosis I GO:0007127 65 37 0,000 0,04566645 0,05546364 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,04566645 0,05543566 ! sister chromatid segregation GO:0000819 58 37 0,000 0,04566645 0,0554077 ! actomyosin structure organization GO:0031032 62 37 0,000 0,04566645 0,05537978 ! organic anion transport GO:0015711 68 37 0,000 0,04566645 0,05535188 ! tissue remodeling GO:0048771 76 37 0,000 0,04566645 0,055324 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,04566645 0,05529616 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,04566645 0,05526835 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,04566645 0,05524056 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,04566645 0,0552128 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,04566645 0,05518507 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,04566645 0,05515737 ! glycogen metabolic process GO:0005977 61 37 0,000 0,04566645 0,05512969 ! pigment metabolic process GO:0042440 80 37 0,000 0,04566645 0,05510204 ! spermatid differentiation GO:0048515 66 37 0,000 0,04566645 0,05507442 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,04566645 0,05504683 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,04687206 0,05647179 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,04687206 0,05644353 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,04687206 0,05641529 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,04687206 0,05638708 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,04687206 0,0563589 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,04687206 0,05633075 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,04687206 0,05630263 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,04687206 0,05627453 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,04687206 0,05624647 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,04687206 0,05621843 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,04687206 0,05619042 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,04687206 0,05616243 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,04687206 0,05613448 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,04687206 0,05610655 ! glucan metabolic process GO:0044042 62 38 0,000 0,04687206 0,05607865 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,04807618 0,0574907 ! mammary gland development GO:0030879 86 39 0,000 0,04807618 0,05746214 ! learning GO:0007612 77 39 0,000 0,04807618 0,05743361 ! ear morphogenesis GO:0042471 60 39 0,000 0,04807618 0,05740511 ! organic ether metabolic process GO:0018904 55 39 0,000 0,04807618 0,05737663 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,04807618 0,05734819 ! segmentation GO:0035282 67 39 0,000 0,04807618 0,05731977 ! ion transmembrane transport GO:0034220 66 39 0,000 0,04807618 0,05729138 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,04807618 0,05726301 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,04807618 0,05723468 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,04807618 0,05720637 ! RNA modification GO:0009451 57 39 0,000 0,04807618 0,0571781 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,04807618 0,05714985 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,04927882 0,05855054 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,04927882 0,05852164 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,04927882 0,05849277 ! feeding behavior GO:0007631 59 40 0,000 0,04927882 0,05846393 ! negative regulation of binding GO:0051100 72 40 0,000 0,04927882 0,05843512 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,04927882 0,05840633 ! mesenchymal cell development GO:0014031 87 40 0,000 0,04927882 0,05837757 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,04927882 0,05834884 ! maintenance of protein location GO:0045185 91 40 0,000 0,04927882 0,05832014 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,05047999 0,05971232 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,05047999 0,05968297 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,05047999 0,05965366 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,05047999 0,05962437 ! gliogenesis GO:0042063 88 41 0,000 0,05047999 0,05959512 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,05047999 0,05956589 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,05047999 0,05953669 ! T cell differentiation GO:0030217 81 41 0,000 0,05047999 0,05950752 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,05047999 0,05947838 ! female gamete generation GO:0007292 61 41 0,000 0,05047999 0,05944927 ! polyol metabolic process GO:0019751 66 41 0,000 0,05047999 0,05942018 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,05047999 0,05939112 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,05167967 0,06077287 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,05167967 0,06074318 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,05167967 0,06071352 ! regulation of tube size GO:0035150 71 42 0,000 0,05167967 0,06068389 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,05167967 0,06065429 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,05167967 0,06062472 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,05167967 0,06059517 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,05167967 0,06056566 ! neuron migration GO:0001764 79 42 0,000 0,05167967 0,06053617 ! regulation of protein secretion GO:0050708 71 42 0,000 0,05167967 0,06050671 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,05167967 0,06047728 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,05287788 0,06184939 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,05287788 0,06181933 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,05287788 0,06178931 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,05287788 0,06175931 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,05287788 0,06172935 ! glucose transport GO:0015758 65 43 0,000 0,05287788 0,06169941 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,05287788 0,0616695 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,05287788 0,06163963 ! neural tube development GO:0021915 77 43 0,000 0,05287788 0,06160978 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,05287788 0,06157996 ! striated muscle contraction GO:0006941 77 43 0,000 0,05287788 0,06155016 ! phagocytosis GO:0006909 90 43 0,000 0,05287788 0,0615204 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,05287788 0,06149067 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,05407462 0,06285195 ! hexose transport GO:0008645 67 44 0,000 0,05407462 0,0628216 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,05407462 0,06279128 ! male sex differentiation GO:0046661 76 44 0,000 0,05407462 0,06276099 ! double-strand break repair GO:0006302 81 44 0,000 0,05407462 0,06273073 ! biopolymer methylation GO:0043414 84 44 0,000 0,05407462 0,0627005 ! B cell differentiation GO:0030183 107 44 0,000 0,05407462 0,0626703 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,05407462 0,06264012 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,05407462 0,06260998 ! developmental growth GO:0048589 82 44 0,000 0,05407462 0,06257986 ! maintenance of location in cell GO:0051651 97 44 0,000 0,05407462 0,06254978 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,05526988 0,06390165 ! glycolysis GO:0006096 65 45 0,000 0,05526988 0,06387096 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,05526988 0,0638403 ! leukocyte migration GO:0050900 68 45 0,000 0,05526988 0,06380966 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,05526988 0,06377906 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,05526988 0,06374848 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,05526988 0,06371794 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,05526988 0,06368742 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,05526988 0,06365694 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,05526988 0,06362648 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,05526988 0,06359605 ! cell growth GO:0016049 84 45 0,000 0,05526988 0,06356565 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,05646368 0,0649076 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,05646368 0,0648766 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,05646368 0,06484563 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,05646368 0,0648147 ! pigmentation GO:0043473 100 46 0,000 0,05646368 0,06478379 ! response to insulin stimulus GO:0032868 95 46 0,000 0,05646368 0,06475291 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,05646368 0,06472206 ! positive regulation of defense response GO:0031349 76 47 0,000 0,057656 0,0660573 ! endosome transport GO:0016197 108 47 0,000 0,057656 0,06602586 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,057656 0,06599445 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,057656 0,06596307 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,057656 0,06593172 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,057656 0,0659004 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,057656 0,06586911 ! methylation GO:0032259 90 47 0,000 0,057656 0,06583784 ! protein homooligomerization GO:0051260 76 47 0,000 0,057656 0,06580661 ! mitochondrial transport GO:0006839 82 48 0,000 0,05884686 0,06713397 ! Notch signaling pathway GO:0007219 96 48 0,000 0,05884686 0,06710215 ! cellular component disassembly GO:0022411 86 48 0,000 0,05884686 0,06707036 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,05884686 0,06703861 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,05884686 0,06700688 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,05884686 0,06697518 ! activation of caspase activity GO:0006919 84 48 0,000 0,05884686 0,06694352 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,05884686 0,06691188 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,05884686 0,06688027 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,05884686 0,0668487 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,06003625 0,06816763 ! regulation of action potential GO:0001508 95 49 0,000 0,06003625 0,06813548 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,06003625 0,06810335 ! regulation of ion transport GO:0043269 77 49 0,000 0,06003625 0,06807126 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,06003625 0,0680392 ! peptide metabolic process GO:0006518 76 49 0,000 0,06003625 0,06800716 ! response to temperature stimulus GO:0009266 76 49 0,000 0,06003625 0,06797516 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,06003625 0,06794319 ! endocrine system development GO:0035270 104 49 0,000 0,06003625 0,06791124 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,06003625 0,06787933 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,06003625 0,06784745 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,06003625 0,06781559 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,06003625 0,06778377 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,06122418 0,06909258 ! neuromuscular process GO:0050905 99 50 0,000 0,06122418 0,06906018 ! regulation of ossification GO:0030278 117 50 0,000 0,06122418 0,06902782 ! inner ear development GO:0048839 79 50 0,000 0,06122418 0,06899549 ! histone modification GO:0016570 91 50 0,000 0,06122418 0,06896319 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,06122418 0,06893092 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,06122418 0,06889868 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,06122418 0,06886647 ! positive regulation of binding GO:0051099 78 51 0,000 0,06241064 0,07016823 ! viral infectious cycle GO:0019058 99 51 0,000 0,06241064 0,07013545 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,06241064 0,07010271 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,06241064 0,07007 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,06241064 0,07003732 ! excretion GO:0007588 83 51 0,000 0,06241064 0,07000467 ! chromatin remodeling GO:0006338 109 51 0,000 0,06241064 0,06997205 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,06241064 0,06993945 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,06241064 0,06990689 ! vesicle organization GO:0016050 107 51 0,000 0,06241064 0,06987436 ! regulation of cell shape GO:0008360 125 51 0,000 0,06241064 0,06984186 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,06241064 0,0698094 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,06359565 0,07110183 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,06359565 0,0710688 ! membrane fusion GO:0006944 110 52 0,000 0,06359565 0,07103581 ! covalent chromatin modification GO:0016569 101 52 0,000 0,06359565 0,07100285 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,06359565 0,07096991 ! amino acid activation GO:0043038 92 52 0,000 0,06359565 0,07093701 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,06359565 0,07090414 ! synapse organization GO:0050808 85 52 0,000 0,06359565 0,0708713 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,0647792 0,07215683 ! RNA catabolic process GO:0006401 93 53 0,000 0,0647792 0,07212344 ! regulation of translational initiation GO:0006446 82 53 0,000 0,0647792 0,07209008 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,0647792 0,07205675 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,0647792 0,07202345 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,0647792 0,07199018 ! cell maturation GO:0048469 100 53 0,000 0,0647792 0,07195695 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,0647792 0,07192374 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,0647792 0,07189057 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,06596129 0,07316868 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,06596129 0,07313496 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,06596129 0,07310127 ! cell recognition GO:0008037 85 54 0,000 0,06596129 0,07306762 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,06596129 0,07303399 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,06596129 0,0730004 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,06596129 0,07296683 ! chloride transport GO:0006821 90 55 0,000 0,06714193 0,07423873 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,06714193 0,07420463 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,06714193 0,07417056 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,06714193 0,07413652 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,06714193 0,07410251 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,06714193 0,07406853 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,06714193 0,07403459 ! aging GO:0007568 103 55 0,000 0,06714193 0,07400067 ! gastrulation GO:0007369 112 55 0,000 0,06714193 0,07396679 ! heart morphogenesis GO:0003007 97 55 0,000 0,06714193 0,07393294 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,06714193 0,07389912 ! nuclear export GO:0051168 97 55 0,000 0,06714193 0,07386533 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,06714193 0,07383157 ! regulation of actin filament length GO:0030832 105 56 0,000 0,06832111 0,07509392 ! sensory perception of smell GO:0007608 80 56 0,000 0,06832111 0,07505963 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,06832111 0,07502537 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,06832111 0,07499114 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,06832111 0,07495695 ! regulation of DNA replication GO:0006275 101 56 0,000 0,06832111 0,07492278 ! proton transport GO:0015992 94 56 0,000 0,06832111 0,07488865 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,06949884 0,0761449 ! muscle fiber development GO:0048747 112 57 0,000 0,06949884 0,07611025 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,06949884 0,07607562 ! lipid modification GO:0030258 97 57 0,000 0,06949884 0,07604102 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,06949884 0,07600646 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,06949884 0,07597193 ! maintenance of location GO:0051235 118 57 0,000 0,06949884 0,07593743 ! hydrogen transport GO:0006818 97 58 0,000 0,07067512 0,07718763 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,07067512 0,07715261 ! regulation of endocytosis GO:0030100 91 58 0,000 0,07067512 0,07711762 ! adult behavior GO:0030534 99 58 0,000 0,07067512 0,07708266 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,07067512 0,07704773 ! positive regulation of secretion GO:0051047 95 59 0,000 0,07184996 0,07829302 ! regulation of cellular component size GO:0032535 109 59 0,000 0,07184996 0,07825758 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,07184996 0,07822217 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,07184996 0,07818679 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,07184996 0,07815145 ! DNA catabolic process GO:0006308 86 59 0,000 0,07184996 0,07811613 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,07184996 0,07808085 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,07302335 0,07932017 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,07302335 0,07928437 ! regulation of heart contraction GO:0008016 110 60 0,000 0,07302335 0,07924861 ! camera-type eye development GO:0043010 116 60 0,000 0,07302335 0,07921288 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,07302335 0,07917718 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,07302335 0,07914152 ! kidney development GO:0001822 122 60 0,000 0,07302335 0,07910588 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,07419529 0,08033927 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,07419529 0,08030313 ! mesoderm development GO:0007498 119 61 0,000 0,07419529 0,08026703 ! tRNA processing GO:0008033 89 61 0,000 0,07419529 0,08023095 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,07419529 0,08019491 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,07419529 0,0801589 ! ear development GO:0043583 103 62 0,000 0,07536579 0,08138693 ! viral reproductive process GO:0022415 126 62 0,000 0,07536579 0,08135042 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,07536579 0,08131394 ! gonad development GO:0008406 98 62 0,000 0,07536579 0,08127749 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,07536579 0,08124108 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,07653485 0,08246433 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,07653485 0,08242742 ! detection of external stimulus GO:0009581 91 63 0,000 0,07653485 0,08239054 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,07653485 0,08235369 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,07653485 0,08231687 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,07770247 0,08353536 ! cell redox homeostasis GO:0045454 102 64 0,000 0,07770247 0,08349805 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,07770247 0,08346078 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,07770247 0,08342354 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,07770247 0,08338633 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,07770247 0,08334915 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,07886865 0,08456238 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,07886865 0,08452471 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,07886865 0,08448708 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,07886865 0,08444948 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,07886865 0,08441191 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,0800334 0,08562044 ! actin filament organization GO:0007015 148 66 0,000 0,0800334 0,08558238 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,0800334 0,08554436 ! extracellular matrix organization GO:0030198 133 66 0,000 0,0800334 0,08550638 ! secondary metabolic process GO:0019748 116 66 0,000 0,0800334 0,08546843 ! developmental maturation GO:0021700 116 66 0,000 0,0800334 0,08543051 ! cell projection assembly GO:0030031 120 66 0,000 0,0800334 0,08539262 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,08119671 0,08659543 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,08119671 0,08655707 ! activation of MAPK activity GO:0000187 115 67 0,000 0,08119671 0,08651873 ! lung development GO:0030324 144 67 0,000 0,08119671 0,08648043 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,08119671 0,08644217 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,08119671 0,08640393 ! hexose catabolic process GO:0019320 104 67 0,000 0,08119671 0,08636574 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,08119671 0,08632757 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,08119671 0,08628944 ! adaptive immune response GO:0002250 119 67 0,000 0,08119671 0,08625134 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,08119671 0,08621328 ! amino acid transport GO:0006865 125 68 0,000 0,0823586 0,08740837 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,0823586 0,08736983 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,0823586 0,08733133 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,0823586 0,08729286 ! viral reproduction GO:0016032 134 68 0,000 0,0823586 0,08725442 ! regulation of lipase activity GO:0060191 130 68 0,000 0,0823586 0,08721601 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,0823586 0,08717764 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,08351905 0,08836712 ! urogenital system development GO:0001655 137 69 0,000 0,08351905 0,08832827 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,08351905 0,08828947 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,08351905 0,08825069 ! antigen processing and presentation GO:0019882 104 69 0,000 0,08351905 0,08821195 ! appendage morphogenesis GO:0035107 135 70 0,000 0,08467807 0,08939685 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,08467807 0,08935765 ! amine catabolic process GO:0009310 117 71 0,000 0,08583566 0,0905395 ! reproductive structure development GO:0048608 113 71 0,000 0,08583566 0,09049983 ! appendage development GO:0048736 136 71 0,000 0,08583566 0,09046019 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,08583566 0,09042058 ! B cell activation GO:0042113 160 71 0,000 0,08583566 0,09038101 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,08583566 0,09034147 ! regulation of immune effector process GO:0002697 137 71 0,000 0,08583566 0,09030197 ! acute inflammatory response GO:0002526 113 72 0,000 0,08699183 0,0914783 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,08699183 0,09143833 ! carbohydrate transport GO:0008643 110 72 0,000 0,08699183 0,0913984 ! respiratory system development GO:0060541 153 72 0,000 0,08699183 0,09135851 ! learning or memory GO:0007611 147 73 0,000 0,08814658 0,09253083 ! regulation of blood pressure GO:0008217 125 73 0,000 0,08814658 0,09249048 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,08814658 0,09245016 ! axon guidance GO:0007411 139 73 0,000 0,08814658 0,09240987 ! fertilization GO:0009566 90 73 0,000 0,08814658 0,09236963 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,0892999 0,09353746 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,0892999 0,09349676 ! neurotransmitter transport GO:0006836 123 74 0,000 0,0892999 0,09345609 ! meiosis GO:0007126 121 74 0,000 0,0892999 0,09341546 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,0892999 0,09337486 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,0892999 0,0933343 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,0892999 0,09329377 ! eye development GO:0001654 143 74 0,000 0,0892999 0,09325328 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,0904518 0,0944152 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,0904518 0,09437426 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,0904518 0,09433335 ! meiotic cell cycle GO:0051321 122 75 0,000 0,0904518 0,09429248 ! rhythmic process GO:0048511 128 75 0,000 0,0904518 0,09425164 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,0904518 0,09421084 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,09160228 0,09536785 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,09160228 0,0953266 ! defense response to bacterium GO:0042742 89 76 0,000 0,09160228 0,09528539 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,09160228 0,09524421 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,09160228 0,09520307 ! regulation of catabolic process GO:0009894 161 76 0,000 0,09160228 0,09516196 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,09275135 0,09631409 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,09275135 0,09627254 ! blood coagulation GO:0007596 146 78 0,000 0,093899 0,09742173 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,093899 0,09737974 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,093899 0,09733779 ! protein oligomerization GO:0051259 139 78 0,000 0,093899 0,09729587 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,09504524 0,09844117 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,09504524 0,09839882 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,09504524 0,09835649 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,09504524 0,09831421 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,09619007 0,09945565 ! muscle cell differentiation GO:0042692 159 80 0,000 0,09619007 0,09941293 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,09619007 0,09937024 ! protein import into nucleus GO:0006606 158 80 0,000 0,09619007 0,0993276 ! inorganic anion transport GO:0015698 138 80 0,000 0,09619007 0,09928498 ! T cell activation GO:0042110 168 81 0,000 0,09733348 0,10042211 ! response to hypoxia GO:0001666 171 81 0,000 0,09733348 0,10037906 ! digestion GO:0007586 112 81 0,000 0,09733348 0,10033606 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,09733348 0,10029309 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,09733348 0,10025015 ! nuclear import GO:0051170 161 81 0,000 0,09733348 0,10020726 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,09733348 0,1001644 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,09847549 0,10129629 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,09847549 0,101253 ! response to drug GO:0042493 143 82 0,000 0,09847549 0,10120975 ! response to nutrient GO:0007584 125 82 0,000 0,09847549 0,10116654 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,09847549 0,10112336 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,09847549 0,10108022 ! response to oxygen levels GO:0070482 176 83 0,000 0,09961609 0,10220738 ! regulation of lyase activity GO:0051339 160 83 0,000 0,09961609 0,10216382 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,10075528 0,10328812 ! hemostasis GO:0007599 158 84 0,000 0,10075528 0,10324413 ! negative regulation of transport GO:0051051 153 84 0,000 0,10075528 0,10320018 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,10075528 0,10315626 ! nucleosome assembly GO:0006334 122 85 0,000 0,10189308 0,10427679 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,10189308 0,10423246 ! amine biosynthetic process GO:0009309 138 86 0,000 0,10302947 0,10535015 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,10302947 0,10530539 ! chromatin assembly GO:0031497 124 86 0,000 0,10302947 0,10526068 ! tube morphogenesis GO:0035239 176 86 0,000 0,10302947 0,105216 ! alcohol catabolic process GO:0046164 130 86 0,000 0,10302947 0,10517136 ! amine transport GO:0015837 155 86 0,000 0,10302947 0,10512676 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,10416446 0,1062398 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,10416446 0,10619478 ! protein localization in nucleus GO:0034504 176 87 0,000 0,10416446 0,1061498 ! regulation of protein transport GO:0051223 154 87 0,000 0,10416446 0,10610486 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,10529805 0,10721418 ! regulation of DNA binding GO:0051101 155 88 0,000 0,10529805 0,10716883 ! gland development GO:0048732 206 88 0,000 0,10529805 0,10712351 ! regulation of neurological system process GO:0031644 148 88 0,000 0,10529805 0,10707823 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,10529805 0,107033 ! cellular defense response GO:0006968 114 89 0,000 0,10643024 0,10813816 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,10643024 0,10809251 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,10643024 0,1080469 ! ossification GO:0001503 188 90 0,000 0,10756104 0,10914883 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,10756104 0,10910281 ! sex differentiation GO:0007548 145 90 0,000 0,10756104 0,10905683 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,10756104 0,1090109 ! bone development GO:0060348 189 91 0,000 0,10869045 0,11010914 ! sterol metabolic process GO:0016125 152 91 0,000 0,10869045 0,1100628 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,10869045 0,1100165 ! regulation of defense response GO:0031347 149 92 0,000 0,10981846 0,11111153 ! nucleosome organization GO:0034728 138 92 0,000 0,10981846 0,11106483 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,10981846 0,11101816 ! vitamin metabolic process GO:0006766 139 92 0,000 0,10981846 0,11097153 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,11094509 0,11206292 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,11094509 0,1120159 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,11094509 0,11196891 ! regulation of membrane potential GO:0042391 164 93 0,000 0,11094509 0,11192196 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,11094509 0,11187505 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,11207032 0,11296238 ! female pregnancy GO:0007565 164 94 0,000 0,11207032 0,11291507 ! regulation of T cell activation GO:0050863 158 94 0,000 0,11207032 0,11286781 ! forebrain development GO:0030900 188 95 0,000 0,11319417 0,11395196 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,11319417 0,1139043 ! leukocyte differentiation GO:0002521 202 96 0,000 0,11431664 0,11498571 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,11431664 0,11493766 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,11431664 0,11488965 ! positive regulation of immune response GO:0050778 156 96 0,000 0,11431664 0,11484168 ! detection of stimulus GO:0051606 151 96 0,000 0,11431664 0,11479375 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,11543772 0,11587115 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,11543772 0,11582283 ! hormone metabolic process GO:0042445 157 97 0,000 0,11543772 0,11577455 ! regulation of protein localization GO:0032880 176 97 0,000 0,11543772 0,11572631 ! response to virus GO:0009615 160 98 0,000 0,11655742 0,11680014 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,11655742 0,11675152 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,11655742 0,11670293 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,11767574 0,11777364 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,11767574 0,11772467 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,11767574 0,11767574 GO:0060538|skeletal muscle organ development,