pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/23438-2-real-Zhou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL4685_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 86 53 4,000 2,112E-08 5,012E-05 ! substrate-bound cell migration, cell extension GO:0006930 5 5 2,000 3,776E-08 4,48E-05 ! substrate-bound cell migration GO:0006929 11 10 2,000 4,506E-07 3,564E-04 ! glycolysis GO:0006096 63 49 3,000 1,111E-06 6,593E-04 ! glucose catabolic process GO:0006007 78 60 3,000 2,526E-06 1,199E-03 ! hexose catabolic process GO:0019320 95 70 3,000 4,697E-06 1,858E-03 ! monosaccharide catabolic process GO:0046365 104 77 3,000 6,878E-06 2,332E-03 ! alcohol catabolic process GO:0046164 119 86 3,000 1,068E-05 3,169E-03 ! positive regulation of smooth muscle cell proliferation GO:0048661 45 28 2,000 1,206E-05 3,18E-03 ! carbohydrate catabolic process GO:0016052 137 100 3,000 1,942E-05 4,608E-03 ! positive regulation of viral genome replication GO:0045070 8 5 1,000 2,501E-05 5,394E-03 ! regulation of retroviral genome replication GO:0045091 8 5 1,000 2,501E-05 4,945E-03 ! regulation of smooth muscle cell proliferation GO:0048660 60 37 2,000 2,833E-05 5,171E-03 ! cysteine metabolic process GO:0006534 8 6 1,000 3,747E-05 6,351E-03 ! induction of apoptosis by intracellular signals GO:0008629 78 42 2,000 4,162E-05 6,585E-03 ! amino acid activation GO:0043038 61 43 2,000 4,47E-05 6,629E-03 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! G1/S transition of mitotic cell cycle GO:0000082 93 44 2,000 4,791E-05 6,688E-03 ! JAK-STAT cascade GO:0007259 62 44 2,000 4,791E-05 6,317E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 5,241E-05 6,545E-03 ! DNA topological change GO:0006265 10 7 1,000 5,241E-05 6,218E-03 ! response to UV GO:0009411 79 47 2,000 5,847E-05 6,607E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 6,981E-05 7,529E-03 ! keratinocyte proliferation GO:0043616 15 8 1,000 6,981E-05 7,202E-03 ! glycerophospholipid biosynthetic process GO:0046474 82 55 2,000 9,378E-05 9,273E-03 ! aging GO:0007568 91 57 2,000 1,044E-04 9,906E-03 ! positive regulation of B cell proliferation GO:0030890 14 10 1,000 1,12E-04 0,01021864 ! DNA ligation GO:0006266 16 10 1,000 1,12E-04 9,84E-03 ! positive regulation of viral reproduction GO:0048524 14 10 1,000 1,12E-04 9,489E-03 ! cell projection assembly GO:0030031 90 59 2,000 1,157E-04 9,468E-03 ! negative regulation of protein kinase activity GO:0006469 110 62 2,000 1,342E-04 0,01061227 ! glycerolipid biosynthetic process GO:0045017 92 62 2,000 1,342E-04 0,01026994 ! negative regulation of kinase activity GO:0033673 112 63 2,000 1,407E-04 0,01043505 ! negative regulation of transferase activity GO:0051348 117 66 2,000 1,616E-04 0,01162205 ! regulation of B cell proliferation GO:0030888 24 13 1,000 1,935E-04 0,01350392 ! axon guidance GO:0007411 116 71 2,000 2,008E-04 0,01361212 ! negative regulation of caspase activity GO:0043154 22 14 1,000 2,255E-04 0,01486437 ! phospholipid biosynthetic process GO:0008654 109 76 2,000 2,456E-04 0,01575152 ! phosphoinositide-mediated signaling GO:0048015 122 76 2,000 2,456E-04 0,015337 ! skin development GO:0043588 28 15 1,000 2,599E-04 0,01581596 ! glycoprotein catabolic process GO:0006516 26 15 1,000 2,599E-04 0,01542057 ! release of cytochrome c from mitochondria GO:0001836 29 15 1,000 2,599E-04 0,01504445 ! response to unfolded protein GO:0006986 113 80 2,000 2,858E-04 0,01614669 ! positive regulation of cell growth GO:0030307 22 16 1,000 2,968E-04 0,01637749 ! negative regulation of peptidase activity GO:0010466 25 17 1,000 3,36E-04 0,01812109 ! regulation of viral genome replication GO:0045069 26 17 1,000 3,36E-04 0,0177184 ! response to protein stimulus GO:0051789 127 85 2,000 3,417E-04 0,01762664 ! tRNA metabolic process GO:0006399 110 87 2,000 3,659E-04 0,01847319 ! interphase of mitotic cell cycle GO:0051329 166 87 2,000 3,659E-04 0,01808833 ! cellular response to unfolded protein GO:0034620 24 18 1,000 3,776E-04 0,01828761 GO:0030968|endoplasmic reticulum unfolded protein response, ! interphase GO:0051325 169 89 2,000 3,912E-04 0,01856424 ! positive regulation of cell size GO:0045793 26 19 1,000 4,216E-04 0,01961784 ! chromosome condensation GO:0030261 32 20 1,000 4,68E-04 0,02135694 ! positive regulation of fibroblast proliferation GO:0048146 30 21 1,000 5,167E-04 0,02313641 ! G2/M transition of mitotic cell cycle GO:0000086 34 21 1,000 5,167E-04 0,02270796 ! apoptotic mitochondrial changes GO:0008637 42 21 1,000 5,167E-04 0,02229509 ! apoptotic nuclear changes GO:0030262 31 21 1,000 5,167E-04 0,02189696 ! negative regulation of Wnt receptor signaling pathway GO:0030178 32 21 1,000 5,167E-04 0,0215128 ! glycerophospholipid metabolic process GO:0006650 143 99 2,000 5,344E-04 0,02186362 ! sulfur amino acid metabolic process GO:0000096 31 23 1,000 6,213E-04 0,02498898 ! regulation of viral reproduction GO:0050792 33 23 1,000 6,213E-04 0,0245725 ! cellular response to extracellular stimulus GO:0031668 37 23 1,000 6,213E-04 0,02416967 ! positive regulation of B cell activation GO:0050871 36 23 1,000 6,213E-04 0,02377984 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 46 24 1,000 6,771E-04 0,02550424 ! response to endoplasmic reticulum stress GO:0034976 32 24 1,000 6,771E-04 0,02510574 ! regulation of fibroblast proliferation GO:0048145 39 25 1,000 7,352E-04 0,02684205 ! negative regulation of phosphorylation GO:0042326 46 25 1,000 7,352E-04 0,02643535 ! ER-nuclear signaling pathway GO:0006984 33 26 1,000 7,957E-04 0,02818254 ! fat cell differentiation GO:0045444 41 27 1,000 8,585E-04 0,02995944 ! negative regulation of phosphorus metabolic process GO:0010563 51 27 1,000 8,585E-04 0,02952525 GO:0045936|negative regulation of phosphate metabolic process, ! serine family amino acid metabolic process GO:0009069 41 29 1,000 9,91E-04 0,0335963 ! spindle organization GO:0007051 39 33 1,000 1,284E-03 0,04290377 ! regulation of B cell activation GO:0050864 55 33 1,000 1,284E-03 0,04230789 ! regulation of Wnt receptor signaling pathway GO:0030111 57 34 1,000 1,363E-03 0,04429188 ! negative regulation of hydrolase activity GO:0051346 56 35 1,000 1,444E-03 0,04629495 ! meiosis I GO:0007127 61 36 1,000 1,527E-03 0,0483161 ! nucleus organization GO:0006997 58 37 1,000 1,613E-03 0,05035442 ! keratinocyte differentiation GO:0030216 55 37 1,000 1,613E-03 0,04970046 ! positive regulation of leukocyte proliferation GO:0070665 64 39 1,000 1,791E-03 0,05447902 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! epidermal cell differentiation GO:0009913 61 42 1,000 2,074E-03 0,0623125 ! response to calcium ion GO:0051592 65 43 1,000 2,173E-03 0,06447056 ! positive regulation of cell cycle GO:0045787 83 45 1,000 2,378E-03 0,06966956 ! regulation of mast cell proliferation GO:0070666 80 50 1,000 2,928E-03 0,08473033 ! regulation of leukocyte proliferation GO:0070663 88 53 1,000 3,284E-03 0,09388204 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of growth GO:0045927 78 58 1,000 3,919E-03 0,11072107 ! DNA damage response, signal transduction GO:0042770 105 58 1,000 3,919E-03 0,10941847 ! chromosome segregation GO:0007059 93 59 1,000 4,053E-03 0,11182874 ! negative regulation of cell growth GO:0030308 123 65 1,000 4,897E-03 0,13357891 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 96 66 1,000 5,045E-03 0,13605168 ! negative regulation of cell size GO:0045792 125 67 1,000 5,195E-03 0,13852352 ! meiosis GO:0007126 110 68 1,000 5,347E-03 0,1409943 GO:0051327|M phase of meiotic cell cycle, ! regulation of caspase activity GO:0043281 104 68 1,000 5,347E-03 0,13944491 ! positive regulation of protein amino acid phosphorylation GO:0001934 103 68 1,000 5,347E-03 0,1379292 ! meiotic cell cycle GO:0051321 111 69 1,000 5,502E-03 0,14037862 ! regulation of endopeptidase activity GO:0052548 106 70 1,000 5,658E-03 0,14282717 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 104 70 1,000 5,658E-03 0,14132372 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 108 73 1,000 6,138E-03 0,15173046 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 110 73 1,000 6,138E-03 0,15016623 ! regulation of peptidase activity GO:0052547 113 75 1,000 6,469E-03 0,1566344 ! positive regulation of phosphorylation GO:0042327 119 75 1,000 6,469E-03 0,15505224 ! response to metal ion GO:0010038 114 76 1,000 6,637E-03 0,15749289 ! positive regulation of ligase activity GO:0051351 114 76 1,000 6,637E-03 0,15593356 ! positive regulation of phosphorus metabolic process GO:0010562 125 77 1,000 6,807E-03 0,15836389 GO:0045937|positive regulation of phosphate metabolic process, ! mitochondrion organization GO:0007005 127 78 1,000 6,979E-03 0,1607926 ! negative regulation of growth GO:0045926 140 78 1,000 6,979E-03 0,15924652 ! regulation of ubiquitin-protein ligase activity GO:0051438 123 79 1,000 7,153E-03 0,16166512 ! response to inorganic substance GO:0010035 127 81 1,000 7,507E-03 0,16806805 ! regulation of ligase activity GO:0051340 129 82 1,000 7,687E-03 0,17048933 ! positive regulation of protein modification process GO:0031401 126 83 1,000 7,869E-03 0,17290854 ! cofactor biosynthetic process GO:0051188 108 83 1,000 7,869E-03 0,17132222 ! positive regulation of lymphocyte activation GO:0051251 134 83 1,000 7,869E-03 0,16976475 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 8,02E-03 0,17145478 ! positive regulation of protein ubiquitination GO:0031398 8 5 0,000 8,02E-03 0,16992393 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 8,02E-03 0,16842018 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 5 0,000 8,02E-03 0,16694281 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 8,02E-03 0,16549114 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! negative regulation of tyrosine phosphorylation of Stat3 protein GO:0042518 13 5 0,000 8,02E-03 0,16406449 GO:0042532|negative regulation of tyrosine phosphorylation of STAT protein, ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 8,02E-03 0,16266223 ! regulation of cGMP biosynthetic process GO:0030826 7 5 0,000 8,02E-03 0,16128373 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 8,02E-03 0,15992841 ! positive regulation of actin filament polymerization GO:0030838 8 5 0,000 8,02E-03 0,15859567 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 7 5 0,000 8,02E-03 0,15728496 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 8,02E-03 0,15599574 ! response to oxygen radical GO:0000305 11 5 0,000 8,02E-03 0,15472749 ! negative regulation of bone resorption GO:0045779 11 5 0,000 8,02E-03 0,15347968 ! myoblast cell fate commitment GO:0048625 8 5 0,000 8,02E-03 0,15225185 ! nucleotide-sugar transport GO:0015780 8 5 0,000 8,02E-03 0,1510435 ! positive regulation of lipid biosynthetic process GO:0046889 7 5 0,000 8,02E-03 0,14985418 ! regulation of interferon-beta production GO:0032648 5 5 0,000 8,02E-03 0,14868344 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 6 5 0,000 8,02E-03 0,14753086 GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 6 5 0,000 8,02E-03 0,14639601 ! female meiosis GO:0007143 8 5 0,000 8,02E-03 0,14527848 ! nose development GO:0043584 10 5 0,000 8,02E-03 0,14417788 ! DNA catabolic process, exonucleolytic GO:0000738 7 5 0,000 8,02E-03 0,14309384 ! regulation of cell adhesion mediated by integrin GO:0033628 15 5 0,000 8,02E-03 0,14202598 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 8,02E-03 0,14097393 ! short-chain fatty acid metabolic process GO:0046459 8 5 0,000 8,02E-03 0,13993736 ! tryptophanyl-tRNA aminoacylation GO:0006436 6 5 0,000 8,02E-03 0,13891592 ! cobalt ion transport GO:0006824 9 5 0,000 8,02E-03 0,13790928 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 8,02E-03 0,13691713 ! SMAD protein complex assembly GO:0007183 10 5 0,000 8,02E-03 0,13593915 ! phospholipid dephosphorylation GO:0046839 7 5 0,000 8,02E-03 0,13497504 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 8,02E-03 0,13402451 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 8,02E-03 0,13308728 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 8,02E-03 0,13216306 ! adaptation of signaling pathway GO:0022401 9 5 0,000 8,02E-03 0,13125159 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! cardiac muscle cell proliferation GO:0060038 7 5 0,000 8,02E-03 0,13035261 GO:0014855|striated muscle cell proliferation, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 8,02E-03 0,12946586 ! negative regulation of gene-specific transcription GO:0032582 10 5 0,000 8,02E-03 0,12859109 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 8,02E-03 0,12772806 ! negative regulation of histone modification GO:0031057 7 5 0,000 8,02E-03 0,12687654 ! malate metabolic process GO:0006108 8 5 0,000 8,02E-03 0,1260363 ! positive regulation of histone modification GO:0031058 6 5 0,000 8,02E-03 0,12520711 ! transcription from mitochondrial promoter GO:0006390 8 5 0,000 8,02E-03 0,12438876 ! clathrin coat assembly GO:0048268 11 5 0,000 8,02E-03 0,12358104 ! Notch receptor processing GO:0007220 8 5 0,000 8,02E-03 0,12278375 ! phototransduction, visible light GO:0007603 7 5 0,000 8,02E-03 0,12199667 ! regulation of dopamine uptake GO:0051584 9 5 0,000 8,02E-03 0,12121962 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 8,02E-03 0,12045241 ! mating behavior GO:0007617 6 5 0,000 8,02E-03 0,11969485 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 8,02E-03 0,11894675 ! copulation GO:0007620 8 5 0,000 8,02E-03 0,11820795 ! protein maturation by protein folding GO:0022417 13 5 0,000 8,02E-03 0,11747828 ! embryonic hemopoiesis GO:0035162 13 5 0,000 8,02E-03 0,11675755 ! regulation of potassium ion transport GO:0043266 9 5 0,000 8,02E-03 0,11604561 ! apoptotic cell clearance GO:0043277 14 5 0,000 8,02E-03 0,11534231 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 9 5 0,000 8,02E-03 0,11464747 ! lipoprotein particle clearance GO:0034381 9 5 0,000 8,02E-03 0,11396096 ! fructose 1,6-bisphosphate metabolic process GO:0030388 8 5 0,000 8,02E-03 0,11328262 ! regulation of smooth muscle cell apoptosis GO:0034391 8 5 0,000 8,02E-03 0,11261231 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 8,02E-03 0,11194989 GO:0046329|negative regulation of JNK cascade, ! oocyte maturation GO:0001556 6 5 0,000 8,02E-03 0,11129521 ! response to axon injury GO:0048678 8 5 0,000 8,02E-03 0,11064814 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 8,02E-03 0,11000856 ! response to protozoan GO:0001562 10 5 0,000 8,02E-03 0,10937633 ! negative regulation of heart contraction GO:0045822 12 5 0,000 8,02E-03 0,10875132 ! lymph vessel development GO:0001945 8 5 0,000 8,02E-03 0,10813341 ! regulation of activin receptor signaling pathway GO:0032925 11 5 0,000 8,02E-03 0,10752249 ! endochondral ossification GO:0001958 13 5 0,000 8,02E-03 0,10691843 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 8,02E-03 0,10632112 ! single strand break repair GO:0000012 5 5 0,000 8,02E-03 0,10573045 ! parathyroid gland development GO:0060017 8 5 0,000 8,02E-03 0,1051463 ! anagen GO:0042640 7 5 0,000 8,02E-03 0,10456858 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 8,02E-03 0,10399716 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 8,02E-03 0,10343196 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 8 5 0,000 8,02E-03 0,10287287 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 8 5 0,000 8,02E-03 0,10231979 ! smooth muscle tissue development GO:0048745 14 5 0,000 8,02E-03 0,10177262 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 8,02E-03 0,10123128 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 8,02E-03 0,10069567 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 8,02E-03 0,10016569 ! cardiac muscle fiber development GO:0048739 8 5 0,000 8,02E-03 0,09964126 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 8,02E-03 0,0991223 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 6 5 0,000 8,02E-03 0,09860871 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 8,02E-03 0,09810042 ! regulation of oligodendrocyte differentiation GO:0048713 15 5 0,000 8,02E-03 0,09759734 GO:0048715|negative regulation of oligodendrocyte differentiation, ! mitochondrion localization, microtubule-mediated GO:0034643 9 5 0,000 8,02E-03 0,09709939 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! negative regulation of RNA splicing GO:0033119 6 5 0,000 8,02E-03 0,0966065 ! ionotropic glutamate receptor signaling pathway GO:0035235 10 5 0,000 8,02E-03 0,09611859 ! positive regulation of isotype switching to IgG isotypes GO:0048304 8 5 0,000 8,02E-03 0,09563558 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 8,02E-03 0,0951574 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 9 5 0,000 8,02E-03 0,09468398 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 8,02E-03 0,09421525 ! tyrosine catabolic process GO:0006572 7 5 0,000 8,02E-03 0,09375114 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 8,02E-03 0,09329157 ! proline biosynthetic process GO:0006561 6 5 0,000 8,02E-03 0,09283649 ! L-serine biosynthetic process GO:0006564 6 5 0,000 8,02E-03 0,09238583 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 8,02E-03 0,09193952 ! polyol catabolic process GO:0046174 7 5 0,000 8,02E-03 0,0914975 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 8,02E-03 0,09105972 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 8,02E-03 0,0906261 ! sister chromatid cohesion GO:0007062 10 5 0,000 8,02E-03 0,09019659 ! response to ATP GO:0033198 6 5 0,000 8,02E-03 0,08977114 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 9 5 0,000 8,02E-03 0,08934967 ! positive regulation of stress fiber formation GO:0051496 15 5 0,000 8,02E-03 0,08893215 ! neutrophil activation GO:0042119 6 5 0,000 8,02E-03 0,08851851 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 8,02E-03 0,08810871 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 8,02E-03 0,08770268 ! response to food GO:0032094 5 5 0,000 8,02E-03 0,08730037 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 8,02E-03 0,08690174 GO:0043088|regulation of Cdc42 GTPase activity, ! positive regulation of transporter activity GO:0032411 5 5 0,000 8,02E-03 0,08650673 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 8 5 0,000 8,02E-03 0,0861153 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 8,02E-03 0,08572739 ! paraxial mesoderm development GO:0048339 9 5 0,000 8,02E-03 0,08534296 ! forebrain neuron development GO:0021884 7 5 0,000 8,02E-03 0,08496197 ! melanosome organization GO:0032438 7 5 0,000 8,02E-03 0,08458436 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 8,02E-03 0,08421009 ! virus-infected cell apoptosis GO:0006926 8 5 0,000 8,02E-03 0,08383912 ! positive regulation of neuroblast proliferation GO:0002052 9 5 0,000 8,02E-03 0,08347141 ! mesodermal cell fate determination GO:0007500 7 5 0,000 8,02E-03 0,0831069 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 8,02E-03 0,08274557 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 8 5 0,000 8,02E-03 0,08238736 ! nucleoside salvage GO:0043174 7 5 0,000 8,02E-03 0,08203224 GO:0006166|purine ribonucleoside salvage, ! lipid glycosylation GO:0030259 6 5 0,000 8,02E-03 0,08168017 ! attachment of GPI anchor to protein GO:0016255 10 5 0,000 8,02E-03 0,08133111 ! negative regulation of platelet activation GO:0010544 8 5 0,000 8,02E-03 0,08098502 GO:0010543|regulation of platelet activation, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 8,02E-03 0,08064187 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 8,02E-03 0,08030161 ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 8,02E-03 0,0799642 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of fatty acid metabolic process GO:0045923 6 5 0,000 8,02E-03 0,07962963 ! early endosome to late endosome transport GO:0045022 11 5 0,000 8,02E-03 0,07929784 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 6 5 0,000 8,02E-03 0,0789688 ! depyrimidination GO:0045008 8 5 0,000 8,02E-03 0,07864248 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 8,02E-03 0,07831885 ! 5S class rRNA transcription GO:0042791 8 5 0,000 8,02E-03 0,07799787 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 5 0,000 8,02E-03 0,07767951 ! neuronal ion channel clustering GO:0045161 8 5 0,000 8,02E-03 0,07736374 ! sodium ion homeostasis GO:0055078 6 5 0,000 8,02E-03 0,07705053 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 8,02E-03 0,07673984 ! monocyte differentiation GO:0030224 7 5 0,000 8,02E-03 0,07643165 ! negative regulation of peptide secretion GO:0002792 8 5 0,000 8,02E-03 0,07612592 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 6 5 0,000 8,02E-03 0,07582263 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 8,02E-03 0,07552175 ! response to UV-C GO:0010225 7 5 0,000 8,02E-03 0,07522324 ! protein targeting to vacuole GO:0006623 6 5 0,000 8,02E-03 0,07492709 ! activated T cell proliferation GO:0050798 7 5 0,000 8,02E-03 0,07463326 ! negative regulation of alpha-beta T cell activation GO:0046636 7 5 0,000 8,02E-03 0,07434172 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! regulation of alpha-beta T cell proliferation GO:0046640 13 5 0,000 8,02E-03 0,07405245 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 8,02E-03 0,07376543 ! regulation of integrin biosynthetic process GO:0045113 9 5 0,000 8,02E-03 0,07348062 ! regulation of killing of cells of another organism GO:0051709 6 5 0,000 8,02E-03 0,073198 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 8,02E-03 0,07291755 ! lymphoid progenitor cell differentiation GO:0002320 12 5 0,000 8,02E-03 0,07263924 ! positive regulation of T cell cytokine production GO:0002726 9 5 0,000 8,02E-03 0,07236304 GO:0032743|positive regulation of interleukin-2 production, ! L-ascorbic acid metabolic process GO:0019852 7 5 0,000 8,02E-03 0,07208894 ! base-excision repair, DNA ligation GO:0006288 5 5 0,000 8,02E-03 0,07181691 ! response to cadmium ion GO:0046686 8 5 0,000 8,02E-03 0,07154692 ! melanosome transport GO:0032402 8 5 0,000 8,02E-03 0,07127895 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 8,02E-03 0,07101299 ! regulation of acetylcholine secretion GO:0014056 10 5 0,000 8,02E-03 0,070749 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 8,02E-03 0,07048697 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 8,02E-03 0,07022687 ! positive T cell selection GO:0043368 10 5 0,000 8,02E-03 0,06996868 ! purine deoxyribonucleotide catabolic process GO:0009155 6 5 0,000 8,02E-03 0,06971238 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 8,02E-03 0,06945796 ! regulation of interleukin-1 production GO:0032652 8 5 0,000 8,02E-03 0,06920538 ! ribosomal subunit assembly GO:0042257 5 5 0,000 8,02E-03 0,06895464 ! base conversion or substitution editing GO:0016553 6 5 0,000 8,02E-03 0,06870571 ! regulation of chondrocyte differentiation GO:0032330 9 5 0,000 8,02E-03 0,06845856 ! negative regulation of monooxygenase activity GO:0032769 10 5 0,000 8,02E-03 0,06821319 ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 8,02E-03 0,06796957 ! positive regulation of interleukin-12 production GO:0032735 5 5 0,000 8,02E-03 0,06772769 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 8,02E-03 0,06748752 ! histone demethylation GO:0016577 10 5 0,000 8,02E-03 0,06724905 ! mitotic recombination GO:0006312 10 5 0,000 8,02E-03 0,06701226 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 5 0,000 8,02E-03 0,06677713 ! regulation of sterol transport GO:0032371 7 5 0,000 8,02E-03 0,06654364 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 8,02E-03 0,06631178 ! sympathetic nervous system development GO:0048485 13 5 0,000 8,02E-03 0,06608153 ! enteric nervous system development GO:0048484 9 5 0,000 8,02E-03 0,06585287 ! oxygen homeostasis GO:0032364 8 5 0,000 8,02E-03 0,0656258 ! establishment of planar polarity GO:0001736 7 5 0,000 8,02E-03 0,06540028 ! lymphocyte costimulation GO:0031294 12 5 0,000 8,02E-03 0,0651763 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 6 5 0,000 8,02E-03 0,06495386 ! transcription termination GO:0006353 8 5 0,000 8,02E-03 0,06473293 ! plasminogen activation GO:0031639 5 5 0,000 8,02E-03 0,06451349 ! B cell homeostasis GO:0001782 12 5 0,000 8,02E-03 0,06429554 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 8,02E-03 0,06407906 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 8,02E-03 0,06386403 ! regulation of hair follicle development GO:0051797 9 5 0,000 8,02E-03 0,06365044 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 8,02E-03 0,06343827 ! apical protein localization GO:0045176 8 5 0,000 8,02E-03 0,06322751 ! definitive hemopoiesis GO:0060216 5 5 0,000 8,02E-03 0,06301815 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 8,02E-03 0,06281017 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 8,02E-03 0,06260355 ! glucocorticoid biosynthetic process GO:0006704 6 5 0,000 8,02E-03 0,0623983 ! regulation of keratinocyte differentiation GO:0045616 7 5 0,000 8,02E-03 0,06219438 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 8,02E-03 0,06199179 ! regulation of centrosome duplication GO:0010824 6 5 0,000 8,02E-03 0,06179052 ! disaccharide metabolic process GO:0005984 9 5 0,000 8,02E-03 0,06159055 ! galactolipid metabolic process GO:0019374 8 5 0,000 8,02E-03 0,06139187 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 8,02E-03 0,06119447 GO:0033015|tetrapyrrole catabolic process, ! positive regulation of T cell mediated cytotoxicity GO:0001916 11 5 0,000 8,02E-03 0,06099834 ! determination of adult lifespan GO:0008340 8 5 0,000 8,02E-03 0,06080345 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 8,02E-03 0,06060981 ! ectodermal gut morphogenesis GO:0048567 6 5 0,000 8,02E-03 0,0604174 GO:0007439|ectodermal gut development, ! somatic stem cell maintenance GO:0035019 14 5 0,000 8,02E-03 0,0602262 ! T cell activation during immune response GO:0002286 9 5 0,000 8,02E-03 0,06003622 ! negative regulation of fibrinolysis GO:0051918 9 5 0,000 8,02E-03 0,05984742 ! negative regulation of lipase activity GO:0060192 7 5 0,000 8,02E-03 0,05965981 ! establishment of apical/basal cell polarity GO:0035089 7 5 0,000 8,02E-03 0,05947338 ! neural plate development GO:0001840 7 5 0,000 8,02E-03 0,0592881 ! regulation of sensory perception GO:0051931 6 5 0,000 8,02E-03 0,05910398 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 10 5 0,000 8,02E-03 0,05892099 ! regulation of histone acetylation GO:0035065 7 5 0,000 8,02E-03 0,05873914 ! sensory cilium assembly GO:0035058 6 5 0,000 8,02E-03 0,0585584 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 14 5 0,000 8,02E-03 0,05837878 ! diacylglycerol metabolic process GO:0046339 8 5 0,000 8,02E-03 0,05820025 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 8,02E-03 0,05802281 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 11 5 0,000 8,02E-03 0,05784645 ! negative regulation of smooth muscle contraction GO:0045986 10 5 0,000 8,02E-03 0,05767115 ! receptor biosynthetic process GO:0032800 6 5 0,000 8,02E-03 0,05749692 ! penetration of zona pellucida GO:0007341 9 5 0,000 8,02E-03 0,05732374 ! drug metabolic process GO:0017144 5 5 0,000 8,02E-03 0,05715159 ! protein amino acid prenylation GO:0018346 9 5 0,000 8,02E-03 0,05698048 ! organ regeneration GO:0031100 7 5 0,000 8,02E-03 0,05681039 ! carnitine metabolic process GO:0009437 5 5 0,000 8,02E-03 0,05664131 GO:0006577|betaine metabolic process, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 130 85 1,000 8,239E-03 0,05801616 GO:0010498|proteasomal protein catabolic process, ! microtubule cytoskeleton organization GO:0000226 133 90 1,000 9,197E-03 0,06456961 ! positive regulation of cell activation GO:0050867 146 90 1,000 9,197E-03 0,06437914 GO:0002696|positive regulation of leukocyte activation, ! tRNA transcription GO:0009304 11 6 0,000 9,617E-03 0,06711763 ! negative regulation of S phase of mitotic cell cycle GO:0045749 13 6 0,000 9,617E-03 0,0669208 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 9,617E-03 0,06672513 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 8 6 0,000 9,617E-03 0,06653059 ! regulation of helicase activity GO:0051095 11 6 0,000 9,617E-03 0,06633719 ! regulation of cGMP metabolic process GO:0030823 8 6 0,000 9,617E-03 0,06614491 ! sleep GO:0030431 13 6 0,000 9,617E-03 0,06595374 ! positive regulation of axon extension GO:0045773 10 6 0,000 9,617E-03 0,06576367 ! negative regulation of small GTPase mediated signal transduction GO:0051058 11 6 0,000 9,617E-03 0,06557469 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 9,617E-03 0,0653868 ! forebrain regionalization GO:0021871 7 6 0,000 9,617E-03 0,06519998 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 9,617E-03 0,06501423 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 9,617E-03 0,06482953 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 9,617E-03 0,06464587 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 9,617E-03 0,06446326 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 18 6 0,000 9,617E-03 0,06428167 ! regulation of protein export from nucleus GO:0046825 8 6 0,000 9,617E-03 0,0641011 ! neuron adhesion GO:0007158 9 6 0,000 9,617E-03 0,06392155 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 9,617E-03 0,063743 ! signal peptide processing GO:0006465 8 6 0,000 9,617E-03 0,06356544 ! embryonic camera-type eye development GO:0031076 11 6 0,000 9,617E-03 0,06338887 GO:0048596|embryonic camera-type eye morphogenesis, ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 9,617E-03 0,06321328 ! glucocorticoid receptor signaling pathway GO:0042921 11 6 0,000 9,617E-03 0,06303866 GO:0031958|corticosteroid receptor signaling pathway, ! citrate metabolic process GO:0006101 10 6 0,000 9,617E-03 0,06286499 ! fibril organization GO:0043206 13 6 0,000 9,617E-03 0,06269229 ! regulation of mitochondrial membrane permeability GO:0046902 12 6 0,000 9,617E-03 0,06252053 ! neurofilament cytoskeleton organization GO:0060052 10 6 0,000 9,617E-03 0,06234971 ! posttranscriptional gene silencing by RNA GO:0035194 14 6 0,000 9,617E-03 0,06217982 GO:0016441|posttranscriptional gene silencing, ! behavioral response to pain GO:0048266 10 6 0,000 9,617E-03 0,06201085 ! protein refolding GO:0042026 13 6 0,000 9,617E-03 0,0618428 ! metabotropic glutamate receptor signaling pathway GO:0007216 8 6 0,000 9,617E-03 0,06167566 ! rhythmic behavior GO:0007622 14 6 0,000 9,617E-03 0,06150942 ! glial cell fate commitment GO:0021781 17 6 0,000 9,617E-03 0,06134407 ! erythrocyte maturation GO:0043249 7 6 0,000 9,617E-03 0,06117961 ! sensory perception of temperature stimulus GO:0050951 12 6 0,000 9,617E-03 0,06101602 ! protein amino acid dealkylation GO:0008214 12 6 0,000 9,617E-03 0,06085332 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 9,617E-03 0,06069147 ! regulation of odontogenesis GO:0042481 8 6 0,000 9,617E-03 0,06053049 ! mechanosensory behavior GO:0007638 8 6 0,000 9,617E-03 0,06037035 ! ovulation from ovarian follicle GO:0001542 7 6 0,000 9,617E-03 0,06021106 ! negative regulation of endocytosis GO:0045806 8 6 0,000 9,617E-03 0,06005261 ! response to interferon-gamma GO:0034341 12 6 0,000 9,617E-03 0,059895 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 9,617E-03 0,0597382 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 9 6 0,000 9,617E-03 0,05958223 ! negative regulation of viral genome replication GO:0045071 8 6 0,000 9,617E-03 0,05942707 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 6 6 0,000 9,617E-03 0,05927271 ! spinal cord dorsal/ventral patterning GO:0021513 8 6 0,000 9,617E-03 0,05911915 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 17 6 0,000 9,617E-03 0,05896639 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 11 6 0,000 9,617E-03 0,05881442 ! cGMP-mediated signaling GO:0019934 11 6 0,000 9,617E-03 0,05866322 ! activation of MAPKKK activity GO:0000185 11 6 0,000 9,617E-03 0,0585128 ! inositol phosphate-mediated signaling GO:0048016 10 6 0,000 9,617E-03 0,05836315 ! protein lipoylation GO:0009249 10 6 0,000 9,617E-03 0,05821427 ! pigment granule organization GO:0048753 11 6 0,000 9,617E-03 0,05806614 ! drug transport GO:0015893 6 6 0,000 9,617E-03 0,05791876 ! transepithelial chloride transport GO:0030321 10 6 0,000 9,617E-03 0,05777213 GO:0070633|transepithelial transport, ! negative regulation of survival gene product expression GO:0008634 9 6 0,000 9,617E-03 0,05762625 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 9,617E-03 0,05748109 ! regulation of defense response to virus by host GO:0050691 7 6 0,000 9,617E-03 0,05733667 ! glutamate catabolic process GO:0006538 11 6 0,000 9,617E-03 0,05719297 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 9,617E-03 0,05704998 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 9,617E-03 0,05690771 ! adenohypophysis development GO:0021984 10 6 0,000 9,617E-03 0,05676615 ! response to pH GO:0009268 10 6 0,000 9,617E-03 0,05662529 ! hyperosmotic response GO:0006972 9 6 0,000 9,617E-03 0,05648513 ! microtubule nucleation GO:0007020 10 6 0,000 9,617E-03 0,05634566 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 6 0,000 9,617E-03 0,05620688 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 6 0,000 9,617E-03 0,05606878 ! melanin biosynthetic process from tyrosine GO:0006583 9 6 0,000 9,617E-03 0,05593136 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 9,617E-03 0,0557946 ! vascular smooth muscle contraction GO:0014829 11 6 0,000 9,617E-03 0,05565852 ! regulation of retinoic acid receptor signaling pathway GO:0048385 13 6 0,000 9,617E-03 0,0555231 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 9,617E-03 0,05538833 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 9,617E-03 0,05525422 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 9,617E-03 0,05512076 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 9,617E-03 0,05498794 ! purine salvage GO:0043101 9 6 0,000 9,617E-03 0,05485575 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 9,617E-03 0,0547242 ! peptidyl-threonine phosphorylation GO:0018107 16 6 0,000 9,617E-03 0,05459329 ! nucleoside transport GO:0015858 7 6 0,000 9,617E-03 0,05446299 ! organic alcohol transport GO:0015850 9 6 0,000 9,617E-03 0,05433332 ! T cell mediated immunity GO:0002456 12 6 0,000 9,617E-03 0,05420426 ! folic acid transport GO:0015884 11 6 0,000 9,617E-03 0,05407581 ! male sex determination GO:0030238 11 6 0,000 9,617E-03 0,05394797 ! carnitine transport GO:0015879 8 6 0,000 9,617E-03 0,05382074 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 9,617E-03 0,0536941 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 9,617E-03 0,05356806 ! negative regulation of DNA recombination GO:0045910 10 6 0,000 9,617E-03 0,05344261 ! positive regulation of exocytosis GO:0045921 9 6 0,000 9,617E-03 0,05331774 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 9,617E-03 0,05319346 ! parturition GO:0007567 13 6 0,000 9,617E-03 0,05306975 ! determination of anterior/posterior axis, embryo GO:0008595 10 6 0,000 9,617E-03 0,05294662 GO:0007351|tripartite regional subdivision, ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 9,617E-03 0,05282406 ! lipopolysaccharide biosynthetic process GO:0009103 6 6 0,000 9,617E-03 0,05270206 ! regulation of centrosome cycle GO:0046605 8 6 0,000 9,617E-03 0,05258063 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 9,617E-03 0,05245975 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 9,617E-03 0,05233943 ! regulation of cholesterol biosynthetic process GO:0045540 8 6 0,000 9,617E-03 0,05221966 ! homeostasis of number of cells within a tissue GO:0048873 10 6 0,000 9,617E-03 0,05210044 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 9,617E-03 0,05198176 ! negative regulation of gliogenesis GO:0014014 17 6 0,000 9,617E-03 0,05186362 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 10 6 0,000 9,617E-03 0,05174602 ! neural nucleus development GO:0048857 12 6 0,000 9,617E-03 0,05162894 ! forebrain morphogenesis GO:0048853 14 6 0,000 9,617E-03 0,0515124 ! hyaluronan metabolic process GO:0030212 7 6 0,000 9,617E-03 0,05139638 ! purine base biosynthetic process GO:0009113 14 6 0,000 9,617E-03 0,05128088 ! interaction with symbiont GO:0051702 9 6 0,000 9,617E-03 0,0511659 ! regulation of dendrite development GO:0050773 13 6 0,000 9,617E-03 0,05105144 ! anterograde axon cargo transport GO:0008089 9 6 0,000 9,617E-03 0,05093748 ! positive regulation of organ growth GO:0046622 7 6 0,000 9,617E-03 0,05082404 ! eating behavior GO:0042755 6 6 0,000 9,617E-03 0,0507111 ! regulation of T cell cytokine production GO:0002724 11 6 0,000 9,617E-03 0,05059865 ! transcription-coupled nucleotide-excision repair GO:0006283 7 6 0,000 9,617E-03 0,05048671 ! response to copper ion GO:0046688 9 6 0,000 9,617E-03 0,05037526 ! negative regulation of lymphocyte mediated immunity GO:0002707 13 6 0,000 9,617E-03 0,0502643 GO:0002704|negative regulation of leukocyte mediated immunity, ! response to exogenous dsRNA GO:0043330 8 6 0,000 9,617E-03 0,05015383 ! establishment of melanosome localization GO:0032401 9 6 0,000 9,617E-03 0,05004384 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 9,617E-03 0,04993434 ! negative regulation of protein kinase B signaling cascade GO:0051898 12 6 0,000 9,617E-03 0,04982531 ! positive regulation of B cell differentiation GO:0045579 10 6 0,000 9,617E-03 0,04971676 ! regulation of dopamine secretion GO:0014059 14 6 0,000 9,617E-03 0,04960868 ! nucleoside catabolic process GO:0009164 7 6 0,000 9,617E-03 0,04950107 ! hair follicle maturation GO:0048820 8 6 0,000 9,617E-03 0,04939392 ! cranial nerve morphogenesis GO:0021602 7 6 0,000 9,617E-03 0,04928724 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 9,617E-03 0,04918102 ! positive regulation of interleukin-5 production GO:0032754 9 6 0,000 9,617E-03 0,04907525 GO:0032736|positive regulation of interleukin-13 production, ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 9,617E-03 0,04896994 ! rhombomere development GO:0021546 6 6 0,000 9,617E-03 0,04886508 ! positive regulation of Rho GTPase activity GO:0032321 12 6 0,000 9,617E-03 0,04876067 ! G2 phase GO:0051319 15 6 0,000 9,617E-03 0,0486567 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 10 6 0,000 9,617E-03 0,04855318 GO:0050000|chromosome localization, ! regulation of mast cell activation GO:0033003 7 6 0,000 9,617E-03 0,04845009 ! muscle cell proliferation GO:0033002 9 6 0,000 9,617E-03 0,04834744 ! membrane to membrane docking GO:0022614 12 6 0,000 9,617E-03 0,04824523 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 10 6 0,000 9,617E-03 0,04814345 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 12 6 0,000 9,617E-03 0,04804209 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 6 0,000 9,617E-03 0,04794116 ! receptor internalization GO:0031623 9 6 0,000 9,617E-03 0,04784066 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 9,617E-03 0,04774057 GO:0031272|regulation of pseudopodium assembly, ! regulation of respiratory burst GO:0060263 9 6 0,000 9,617E-03 0,0476409 ! coenzyme A metabolic process GO:0015936 9 6 0,000 9,617E-03 0,04754165 ! myeloid dendritic cell activation GO:0001773 11 6 0,000 9,617E-03 0,04744281 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 12 6 0,000 9,617E-03 0,04734438 ! peptidyl-histidine modification GO:0018202 10 6 0,000 9,617E-03 0,04724636 ! axonal fasciculation GO:0007413 10 6 0,000 9,617E-03 0,04714875 ! regulation of muscle cell apoptosis GO:0010660 9 6 0,000 9,617E-03 0,04705153 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 9,617E-03 0,04695472 GO:0015991|ATP hydrolysis coupled proton transport, ! midbrain development GO:0030901 7 6 0,000 9,617E-03 0,0468583 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 9,617E-03 0,04676228 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 9,617E-03 0,04666665 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 7 6 0,000 9,617E-03 0,04657141 ! progesterone metabolic process GO:0042448 8 6 0,000 9,617E-03 0,04647656 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 9,617E-03 0,0463821 ! glycolipid catabolic process GO:0019377 14 6 0,000 9,617E-03 0,04628802 GO:0046479|glycosphingolipid catabolic process, ! nonprotein amino acid metabolic process GO:0019794 10 6 0,000 9,617E-03 0,04619432 ! negative regulation of axon extension GO:0030517 13 6 0,000 9,617E-03 0,046101 ! removal of superoxide radicals GO:0019430 10 6 0,000 9,617E-03 0,04600805 ! triglyceride catabolic process GO:0019433 8 6 0,000 9,617E-03 0,04591548 ! protein modification by small protein removal GO:0070646 10 6 0,000 9,617E-03 0,04582328 GO:0016579|protein deubiquitination, ! adult feeding behavior GO:0008343 6 6 0,000 9,617E-03 0,04573145 ! regulation of Rac protein signal transduction GO:0035020 9 6 0,000 9,617E-03 0,04563999 ! glial cell migration GO:0008347 11 6 0,000 9,617E-03 0,04554889 ! blastocyst growth GO:0001832 17 6 0,000 9,617E-03 0,04545815 ! pigment granule transport GO:0051904 12 6 0,000 9,617E-03 0,04536778 ! lymphocyte activation during immune response GO:0002285 10 6 0,000 9,617E-03 0,04527776 ! cerebellar cortex formation GO:0021697 9 6 0,000 9,617E-03 0,04518811 ! catecholamine transport GO:0051937 7 6 0,000 9,617E-03 0,0450988 ! hemopoietic progenitor cell differentiation GO:0002244 14 6 0,000 9,617E-03 0,04500985 ! positive regulation of actin filament bundle formation GO:0032233 16 6 0,000 9,617E-03 0,04492125 ! organ or tissue specific immune response GO:0002251 7 6 0,000 9,617E-03 0,04483299 ! positive regulation of smooth muscle contraction GO:0045987 10 6 0,000 9,617E-03 0,04474508 ! spindle assembly GO:0051225 6 6 0,000 9,617E-03 0,04465752 ! ensheathment of axons in the peripheral nervous system GO:0032292 15 6 0,000 9,617E-03 0,0445703 GO:0022011|myelination in the peripheral nervous system, ! protein prenylation GO:0018342 10 6 0,000 9,617E-03 0,04448342 ! negative regulation of synaptic transmission GO:0050805 12 6 0,000 9,617E-03 0,04439687 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 9,617E-03 0,04431067 ! NAD biosynthetic process GO:0009435 9 6 0,000 9,617E-03 0,04422479 ! positive regulation of coagulation GO:0050820 11 6 0,000 9,617E-03 0,04413925 ! cellular anion homeostasis GO:0030002 9 6 0,000 9,617E-03 0,04405404 GO:0055081|anion homeostasis, ! cell cycle arrest GO:0007050 171 93 1,000 9,795E-03 0,04478322 ! sulfur metabolic process GO:0006790 136 99 1,000 0,01104016 0,05038136 ! behavioral response to cocaine GO:0048148 13 7 0,000 0,01121053 0,05106065 ! autophagic vacuole formation GO:0000045 12 7 0,000 0,01121053 0,05096283 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01121053 0,05086539 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 10 7 0,000 0,01121053 0,05076832 ! chaperone mediated protein folding requiring cofactor GO:0051085 9 7 0,000 0,01121053 0,05067162 ! prostate gland development GO:0030850 11 7 0,000 0,01121053 0,05057528 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01121053 0,05047931 ! regulation of hormone biosynthetic process GO:0046885 12 7 0,000 0,01121053 0,05038371 ! synaptonemal complex assembly GO:0007130 11 7 0,000 0,01121053 0,05028847 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 10 7 0,000 0,01121053 0,05019358 ! male meiosis GO:0007140 10 7 0,000 0,01121053 0,05009906 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01121053 0,05000488 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! reproductive behavior GO:0019098 12 7 0,000 0,01121053 0,04991107 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01121053 0,0498176 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01121053 0,04972448 ! oligopeptide transport GO:0006857 11 7 0,000 0,01121053 0,04963171 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01121053 0,04953929 GO:0051923|sulfation, ! N-terminal protein amino acid acetylation GO:0006474 9 7 0,000 0,01121053 0,04944721 ! establishment of tissue polarity GO:0007164 10 7 0,000 0,01121053 0,04935547 ! receptor guanylyl cyclase signaling pathway GO:0007168 7 7 0,000 0,01121053 0,04926407 ! RNA methylation GO:0001510 11 7 0,000 0,01121053 0,04917301 ! negative regulation of cell-cell adhesion GO:0022408 20 7 0,000 0,01121053 0,04908229 ! positive regulation of cell-cell adhesion GO:0022409 17 7 0,000 0,01121053 0,04899189 ! pericardium development GO:0060039 9 7 0,000 0,01121053 0,04890184 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01121053 0,04881211 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01121053 0,04872271 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01121053 0,04863364 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01121053 0,04854489 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01121053 0,04845646 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01121053 0,04836836 ! opsonization GO:0008228 9 7 0,000 0,01121053 0,04828058 ! tachykinin receptor signaling pathway GO:0007217 12 7 0,000 0,01121053 0,04819311 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01121053 0,04810596 ! regulation of dopamine metabolic process GO:0042053 10 7 0,000 0,01121053 0,04801913 GO:0042069|regulation of catecholamine metabolic process, ! glucocorticoid metabolic process GO:0008211 8 7 0,000 0,01121053 0,04793261 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01121053 0,0478464 ! chemosensory behavior GO:0007635 9 7 0,000 0,01121053 0,0477605 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01121053 0,04767491 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01121053 0,04758962 ! leukocyte degranulation GO:0043299 11 7 0,000 0,01121053 0,04750464 ! positive regulation of glycolysis GO:0045821 13 7 0,000 0,01121053 0,04741996 ! DNA ligation during DNA repair GO:0051103 10 7 0,000 0,01121053 0,04733558 ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01121053 0,04725151 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01121053 0,04716773 ! lipopolysaccharide metabolic process GO:0008653 7 7 0,000 0,01121053 0,04708425 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01121053 0,04700106 ! spinal cord patterning GO:0021511 9 7 0,000 0,01121053 0,04691816 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01121053 0,04683556 ! thymic T cell selection GO:0045061 15 7 0,000 0,01121053 0,04675325 ! regulation of transcriptional preinitiation complex assembly GO:0045898 11 7 0,000 0,01121053 0,04667123 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01121053 0,04658949 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01121053 0,04650804 ! ovulation GO:0030728 8 7 0,000 0,01121053 0,04642687 ! regulation of isotype switching to IgG isotypes GO:0048302 11 7 0,000 0,01121053 0,04634599 ! histidine metabolic process GO:0006547 7 7 0,000 0,01121053 0,04626539 GO:0009075|histidine family amino acid metabolic process, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 7 0,000 0,01121053 0,04618507 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01121053 0,04610502 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! deoxyribonucleotide biosynthetic process GO:0009263 9 7 0,000 0,01121053 0,04602526 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 0,01121053 0,04594577 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! ER overload response GO:0006983 8 7 0,000 0,01121053 0,04586655 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01121053 0,04578761 ! endosome organization GO:0007032 10 7 0,000 0,01121053 0,04570893 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01121053 0,04563053 GO:0021940|positive regulation of granule cell precursor proliferation, ! positive regulation of interleukin-8 biosynthetic process GO:0045416 8 7 0,000 0,01121053 0,04555239 ! phasic smooth muscle contraction GO:0014821 13 7 0,000 0,01121053 0,04547453 ! urea metabolic process GO:0019627 9 7 0,000 0,01121053 0,04539693 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 14 7 0,000 0,01121053 0,04531959 ! vesicle fusion GO:0006906 15 7 0,000 0,01121053 0,04524251 ! positive regulation of insulin secretion GO:0032024 9 7 0,000 0,01121053 0,0451657 ! maintenance of protein location in nucleus GO:0051457 17 7 0,000 0,01121053 0,04508915 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01121053 0,04501286 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 10 7 0,000 0,01121053 0,04493682 GO:0046464|acylglycerol catabolic process, ! asymmetric protein localization GO:0008105 10 7 0,000 0,01121053 0,04486104 ! organ growth GO:0035265 13 7 0,000 0,01121053 0,04478552 ! positive regulation of mesenchymal cell proliferation GO:0002053 10 7 0,000 0,01121053 0,04471025 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01121053 0,04463523 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 7 0,000 0,01121053 0,04456047 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 8 7 0,000 0,01121053 0,04448595 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! retinol metabolic process GO:0042572 9 7 0,000 0,01121053 0,04441168 ! positive regulation of mitotic cell cycle GO:0045931 13 7 0,000 0,01121053 0,04433766 ! rRNA modification GO:0000154 12 7 0,000 0,01121053 0,04426389 ! negative regulation of translational initiation GO:0045947 9 7 0,000 0,01121053 0,04419036 ! DNA damage response, signal transduction resulting in transcription GO:0042772 14 7 0,000 0,01121053 0,04411708 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 20 7 0,000 0,01121053 0,04404404 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01121053 0,04397124 ! response to UV-B GO:0010224 11 7 0,000 0,01121053 0,04389868 ! astrocyte development GO:0014002 15 7 0,000 0,01121053 0,04382636 ! intermediate filament organization GO:0045109 12 7 0,000 0,01121053 0,04375427 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01121053 0,04368243 ! fibrinolysis GO:0042730 9 7 0,000 0,01121053 0,04361082 ! peptidyl-arginine modification GO:0018195 9 7 0,000 0,01121053 0,04353944 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 7 0,000 0,01121053 0,0434683 ! blastoderm segmentation GO:0007350 11 7 0,000 0,01121053 0,04339739 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01121053 0,04332671 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01121053 0,04325626 ! regulation of fat cell differentiation GO:0045598 10 7 0,000 0,01121053 0,04318604 ! melanosome localization GO:0032400 10 7 0,000 0,01121053 0,04311604 ! enucleate erythrocyte differentiation GO:0043353 10 7 0,000 0,01121053 0,04304628 ! regulation of interleukin-5 production GO:0032674 10 7 0,000 0,01121053 0,04297673 ! glycosylceramide metabolic process GO:0006677 10 7 0,000 0,01121053 0,04290742 ! mast cell activation GO:0045576 10 7 0,000 0,01121053 0,04283832 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01121053 0,04276945 ! negative regulation of focal adhesion formation GO:0051895 16 7 0,000 0,01121053 0,0427008 ! gas homeostasis GO:0033483 12 7 0,000 0,01121053 0,04263237 ! negative regulation of T cell differentiation GO:0045581 9 7 0,000 0,01121053 0,04256416 ! phosphatidylinositol biosynthetic process GO:0006661 11 7 0,000 0,01121053 0,04249616 ! Schwann cell development GO:0014044 16 7 0,000 0,01121053 0,04242839 ! dendrite morphogenesis GO:0048813 12 7 0,000 0,01121053 0,04236083 ! regulation of interleukin-13 production GO:0032656 12 7 0,000 0,01121053 0,04229348 ! positive regulation of interleukin-4 production GO:0032753 10 7 0,000 0,01121053 0,04222635 ! molybdopterin cofactor biosynthetic process GO:0032324 10 7 0,000 0,01121053 0,04215943 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 11 7 0,000 0,01121053 0,04209272 ! neural tube patterning GO:0021532 8 7 0,000 0,01121053 0,04202622 ! histone ubiquitination GO:0016574 10 7 0,000 0,01121053 0,04195993 ! regulation of meiosis GO:0040020 12 7 0,000 0,01121053 0,04189386 GO:0051445|regulation of meiotic cell cycle, ! eye photoreceptor cell differentiation GO:0001754 14 7 0,000 0,01121053 0,04182799 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 12 7 0,000 0,01121053 0,04176232 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01121053 0,04169686 GO:0002714|positive regulation of B cell mediated immunity, ! mitochondrion morphogenesis GO:0070584 12 7 0,000 0,01121053 0,04163161 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01121053 0,04156656 ! regulation of cell division GO:0051302 9 7 0,000 0,01121053 0,04150171 ! regulation of inflammatory response to antigenic stimulus GO:0002861 14 7 0,000 0,01121053 0,04143707 ! neutrophil homeostasis GO:0001780 8 7 0,000 0,01121053 0,04137263 ! regulation of macrophage activation GO:0043030 12 7 0,000 0,01121053 0,04130838 ! negative regulation of nuclear division GO:0051784 18 7 0,000 0,01121053 0,04124434 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01121053 0,04118049 ! diuresis GO:0030146 11 7 0,000 0,01121053 0,04111684 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 9 7 0,000 0,01121053 0,04105339 ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01121053 0,04099014 ! thiamin metabolic process GO:0006772 8 7 0,000 0,01121053 0,04092707 ! positive regulation of leukocyte chemotaxis GO:0002690 15 7 0,000 0,01121053 0,04086421 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of epidermal cell differentiation GO:0045604 10 7 0,000 0,01121053 0,04080153 ! negative regulation of transmission of nerve impulse GO:0051970 13 7 0,000 0,01121053 0,04073905 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01121053 0,04067676 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01121053 0,04061465 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01121053 0,04055274 ! lymph node development GO:0048535 9 7 0,000 0,01121053 0,04049102 ! anterior/posterior axis specification GO:0009948 11 7 0,000 0,01121053 0,04042948 ! negative regulation of viral reproduction GO:0048525 9 7 0,000 0,01121053 0,04036813 ! regulation of T cell mediated cytotoxicity GO:0001914 15 7 0,000 0,01121053 0,04030697 ! positive regulation of glucose import GO:0046326 7 7 0,000 0,01121053 0,04024599 GO:0010828|positive regulation of glucose transport, ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01121053 0,04018519 ! ATP catabolic process GO:0006200 10 7 0,000 0,01121053 0,04012458 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01121053 0,04006415 ! positive regulation of fibrinolysis GO:0051919 8 7 0,000 0,01121053 0,04000391 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01121053 0,03994384 ! negative regulation of calcium ion transport GO:0051926 8 7 0,000 0,01121053 0,03988396 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01121053 0,03982425 ! positive regulation of blood vessel endothelial cell migration GO:0043536 17 7 0,000 0,01121053 0,03976472 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01121053 0,03970537 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01121053 0,0396462 ! muscle adaptation GO:0043500 12 7 0,000 0,01121053 0,0395872 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01121053 0,03952838 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 8 7 0,000 0,01121053 0,03946973 ! retina homeostasis GO:0001895 9 7 0,000 0,01121053 0,03941126 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01121053 0,03935296 ! regulation of growth hormone secretion GO:0060123 14 7 0,000 0,01121053 0,03929483 ! regulation of T cell receptor signaling pathway GO:0050856 12 7 0,000 0,01121053 0,03923687 ! positive regulation of microtubule polymerization GO:0031116 12 7 0,000 0,01121053 0,03917908 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01121053 0,03912147 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 8 0,000 0,01280207 0,04460985 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 16 8 0,000 0,01280207 0,04454444 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01280207 0,04447922 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! oligosaccharide biosynthetic process GO:0009312 14 8 0,000 0,01280207 0,04441419 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 8 0,000 0,01280207 0,04434935 ! negative regulation of cellular catabolic process GO:0031330 10 8 0,000 0,01280207 0,0442847 ! positive regulation of small GTPase mediated signal transduction GO:0051057 16 8 0,000 0,01280207 0,04422024 GO:0046579|positive regulation of Ras protein signal transduction, ! generation of neurons in the forebrain GO:0021872 11 8 0,000 0,01280207 0,04415597 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01280207 0,04409188 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01280207 0,04402798 ! neutral lipid catabolic process GO:0046461 11 8 0,000 0,01280207 0,04396426 ! N-glycan processing GO:0006491 12 8 0,000 0,01280207 0,04390073 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01280207 0,04383738 ! glycosaminoglycan catabolic process GO:0006027 11 8 0,000 0,01280207 0,04377422 ! negative regulation of JAK-STAT cascade GO:0046426 18 8 0,000 0,01280207 0,04371123 ! mRNA stabilization GO:0048255 16 8 0,000 0,01280207 0,04364843 GO:0043489|RNA stabilization, ! induction of positive chemotaxis GO:0050930 16 8 0,000 0,01280207 0,0435858 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01280207 0,04352336 ! lipoprotein transport GO:0042953 14 8 0,000 0,01280207 0,0434611 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01280207 0,04339901 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01280207 0,0433371 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01280207 0,04327536 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01280207 0,04321381 ! amyloid precursor protein catabolic process GO:0042987 13 8 0,000 0,01280207 0,04315242 ! bile acid and bile salt transport GO:0015721 12 8 0,000 0,01280207 0,04309121 ! ganglioside metabolic process GO:0001573 16 8 0,000 0,01280207 0,04303018 ! regulation of mesenchymal cell proliferation GO:0010464 12 8 0,000 0,01280207 0,04296932 ! reflex GO:0060004 16 8 0,000 0,01280207 0,04290862 ! positive regulation of isotype switching GO:0045830 16 8 0,000 0,01280207 0,0428481 GO:0045911|positive regulation of DNA recombination, ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01280207 0,04278775 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of interleukin-12 biosynthetic process GO:0045075 10 8 0,000 0,01280207 0,04272757 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01280207 0,04266756 ! glycerolipid catabolic process GO:0046503 11 8 0,000 0,01280207 0,04260772 ! positive regulation of chemokine biosynthetic process GO:0045080 9 8 0,000 0,01280207 0,04254805 ! hemoglobin metabolic process GO:0020027 12 8 0,000 0,01280207 0,04248854 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01280207 0,0424292 ! nerve growth factor receptor signaling pathway GO:0048011 12 8 0,000 0,01280207 0,04237002 ! insulin-like growth factor receptor signaling pathway GO:0048009 16 8 0,000 0,01280207 0,04231101 ! adrenal gland development GO:0030325 18 8 0,000 0,01280207 0,04225216 ! embryonic cranial skeleton morphogenesis GO:0048701 12 8 0,000 0,01280207 0,04219348 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01280207 0,04213496 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01280207 0,0420766 ! proline metabolic process GO:0006560 9 8 0,000 0,01280207 0,0420184 ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01280207 0,04196037 ! regulation of interleukin-8 biosynthetic process GO:0045414 10 8 0,000 0,01280207 0,04190249 ! regulation of pigmentation during development GO:0048070 18 8 0,000 0,01280207 0,04184477 ! central nervous system neuron axonogenesis GO:0021955 16 8 0,000 0,01280207 0,04178722 GO:0021952|central nervous system projection neuron axonogenesis, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 15 8 0,000 0,01280207 0,04172982 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01280207 0,04167257 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01280207 0,04161549 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of activated T cell proliferation GO:0042104 19 8 0,000 0,01280207 0,04155856 ! galactose metabolic process GO:0006012 14 8 0,000 0,01280207 0,04150178 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01280207 0,04144516 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01280207 0,0413887 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01280207 0,04133239 ! neurotransmitter catabolic process GO:0042135 16 8 0,000 0,01280207 0,04127623 ! ruffle organization GO:0031529 12 8 0,000 0,01280207 0,04122022 ! osteoblast development GO:0002076 14 8 0,000 0,01280207 0,04116437 ! macroautophagy GO:0016236 14 8 0,000 0,01280207 0,04110867 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01280207 0,04105312 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01280207 0,04099771 ! regulation of Notch signaling pathway GO:0008593 22 8 0,000 0,01280207 0,04094246 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01280207 0,04088736 GO:0030204|chondroitin sulfate metabolic process, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 14 8 0,000 0,01280207 0,0408324 ! G1 DNA damage checkpoint GO:0031571 19 8 0,000 0,01280207 0,04077759 ! protein retention in ER lumen GO:0006621 16 8 0,000 0,01280207 0,04072293 ! cardiac muscle cell differentiation GO:0055007 12 8 0,000 0,01280207 0,04066841 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 8 0,000 0,01280207 0,04061405 ! regulation of circadian rhythm GO:0042752 13 8 0,000 0,01280207 0,04055982 ! pigment granule localization GO:0051875 14 8 0,000 0,01280207 0,04050574 ! positive regulation of cytokine production during immune response GO:0002720 12 8 0,000 0,01280207 0,04045181 ! antigen processing and presentation of endogenous antigen GO:0019883 14 8 0,000 0,01280207 0,04039801 ! response to tropane GO:0014073 14 8 0,000 0,01280207 0,04034436 GO:0042220|response to cocaine, ! positive regulation of systemic arterial blood pressure GO:0003084 12 8 0,000 0,01280207 0,04029086 ! embryonic axis specification GO:0000578 12 8 0,000 0,01280207 0,04023749 ! negative regulation of interferon-gamma production GO:0032689 12 8 0,000 0,01280207 0,04018427 ! negative regulation of systemic arterial blood pressure GO:0003085 18 8 0,000 0,01280207 0,04013118 ! sphingomyelin metabolic process GO:0006684 11 8 0,000 0,01280207 0,04007824 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01280207 0,04002544 GO:0016180|snRNA processing, ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 0,01280207 0,03997277 ! regulation of focal adhesion formation GO:0051893 17 8 0,000 0,01280207 0,03992024 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01280207 0,03986786 ! regulation of mitochondrial membrane potential GO:0051881 14 8 0,000 0,01280207 0,0398156 ! regulation of interleukin-10 production GO:0032653 12 8 0,000 0,01280207 0,03976349 ! positive regulation of monooxygenase activity GO:0032770 12 8 0,000 0,01280207 0,03971151 ! protein import into peroxisome matrix GO:0016558 15 8 0,000 0,01280207 0,03965967 ! establishment of nucleus localization GO:0040023 14 8 0,000 0,01280207 0,03960796 ! icosanoid secretion GO:0032309 12 8 0,000 0,01280207 0,03955639 GO:0050482|arachidonic acid secretion, ! intracellular lipid transport GO:0032365 14 8 0,000 0,01280207 0,03950495 ! regulation of transcription from RNA polymerase III promoter GO:0006359 11 8 0,000 0,01280207 0,03945364 ! negative regulation of oxidoreductase activity GO:0051354 13 8 0,000 0,01280207 0,03940247 ! positive regulation of interleukin-1 beta secretion GO:0050718 10 8 0,000 0,01280207 0,03935143 ! regulation of T-helper 1 type immune response GO:0002825 10 8 0,000 0,01280207 0,03930052 ! S phase GO:0051320 8 8 0,000 0,01280207 0,03924975 GO:0000084|S phase of mitotic cell cycle, ! negative regulation of neuroblast proliferation GO:0007406 25 8 0,000 0,01280207 0,0391991 ! regulation of macrophage differentiation GO:0045649 15 8 0,000 0,01280207 0,03914859 ! negative regulation of osteoclast differentiation GO:0045671 12 8 0,000 0,01280207 0,03909821 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01280207 0,03904795 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 8 0,000 0,01280207 0,03899783 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01280207 0,03894783 ! melanin biosynthetic process GO:0042438 11 8 0,000 0,01280207 0,03889796 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01280207 0,03884822 ! regulation of synaptogenesis GO:0051963 12 8 0,000 0,01280207 0,0387986 ! hormone catabolic process GO:0042447 13 8 0,000 0,01280207 0,03874911 ! nicotinamide nucleotide biosynthetic process GO:0019359 12 8 0,000 0,01280207 0,03869975 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01280207 0,03865052 ! positive regulation of ATPase activity GO:0032781 16 8 0,000 0,01280207 0,03860141 ! trophectodermal cell differentiation GO:0001829 10 8 0,000 0,01280207 0,03855242 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01280207 0,03850356 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01280207 0,03845482 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01280207 0,0384062 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 0,01280207 0,03835771 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01280207 0,03830934 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01280207 0,03826109 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 0,01280207 0,03821296 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 8 0,000 0,01280207 0,03816496 ! negative regulation of B cell activation GO:0050869 17 8 0,000 0,01280207 0,03811707 ! behavioral response to nicotine GO:0035095 13 8 0,000 0,01280207 0,03806931 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01280207 0,03802166 GO:0000076|DNA replication checkpoint, ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 0,01280207 0,03797413 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 16 8 0,000 0,01280207 0,03792672 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 14 8 0,000 0,01280207 0,03787943 ! regulation of microtubule polymerization GO:0031113 14 8 0,000 0,01280207 0,03783226 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01439112 0,04247528 ! regulation of developmental growth GO:0048638 14 9 0,000 0,01439112 0,04242251 ! negative regulation of smooth muscle cell proliferation GO:0048662 15 9 0,000 0,01439112 0,04236988 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01439112 0,04231738 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 9 0,000 0,01439112 0,042265 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 11 9 0,000 0,01439112 0,04221276 ! negative regulation of lipid biosynthetic process GO:0051055 13 9 0,000 0,01439112 0,04216065 ! glycerol-3-phosphate metabolic process GO:0006072 11 9 0,000 0,01439112 0,04210866 ! regulation of cellular amine metabolic process GO:0033238 12 9 0,000 0,01439112 0,0420568 ! cell volume homeostasis GO:0006884 14 9 0,000 0,01439112 0,04200507 ! regulation of epidermal growth factor receptor activity GO:0007176 14 9 0,000 0,01439112 0,04195347 GO:0010469|regulation of receptor activity, ! regulation of smooth muscle cell migration GO:0014910 22 9 0,000 0,01439112 0,04190199 ! UTP metabolic process GO:0046051 10 9 0,000 0,01439112 0,04185064 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! prostaglandin biosynthetic process GO:0001516 15 9 0,000 0,01439112 0,04179942 GO:0046457|prostanoid biosynthetic process, ! succinate metabolic process GO:0006105 16 9 0,000 0,01439112 0,04174832 ! smoothened signaling pathway GO:0007224 10 9 0,000 0,01439112 0,04169734 ! protein complex disassembly GO:0043241 17 9 0,000 0,01439112 0,04164649 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01439112 0,04159577 ! estrogen metabolic process GO:0008210 16 9 0,000 0,01439112 0,04154516 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01439112 0,04149468 ! photoreceptor cell development GO:0042461 17 9 0,000 0,01439112 0,04144432 GO:0046530|photoreceptor cell differentiation, ! cytoplasmic sequestering of transcription factor GO:0042994 12 9 0,000 0,01439112 0,04139409 ! negative regulation of muscle cell differentiation GO:0051148 10 9 0,000 0,01439112 0,04134398 ! microtubule bundle formation GO:0001578 14 9 0,000 0,01439112 0,04129398 ! T-helper 1 type immune response GO:0042088 13 9 0,000 0,01439112 0,04124411 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 22 9 0,000 0,01439112 0,04119436 ! lung alveolus development GO:0048286 18 9 0,000 0,01439112 0,04114473 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01439112 0,04109522 ! pseudouridine synthesis GO:0001522 10 9 0,000 0,01439112 0,04104582 ! endothelial cell differentiation GO:0045446 17 9 0,000 0,01439112 0,04099655 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01439112 0,04094739 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01439112 0,04089835 ! endoderm development GO:0007492 12 9 0,000 0,01439112 0,04084943 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01439112 0,04080063 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01439112 0,04075194 ! myeloid leukocyte mediated immunity GO:0002444 12 9 0,000 0,01439112 0,04070337 ! astrocyte differentiation GO:0048708 17 9 0,000 0,01439112 0,04065491 ! L-phenylalanine metabolic process GO:0006558 11 9 0,000 0,01439112 0,04060657 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 10 9 0,000 0,01439112 0,04055834 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01439112 0,04051023 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 13 9 0,000 0,01439112 0,04046223 ! reverse cholesterol transport GO:0043691 17 9 0,000 0,01439112 0,04041435 ! indolalkylamine metabolic process GO:0006586 15 9 0,000 0,01439112 0,04036658 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! melanin metabolic process GO:0006582 15 9 0,000 0,01439112 0,04031892 ! embryonic eye morphogenesis GO:0048048 15 9 0,000 0,01439112 0,04027137 ! macrophage activation GO:0042116 14 9 0,000 0,01439112 0,04022394 ! multicellular organism growth GO:0035264 16 9 0,000 0,01439112 0,04017662 ! retrograde transport, endosome to Golgi GO:0042147 14 9 0,000 0,01439112 0,04012941 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 0,01439112 0,0400823 ! neuron apoptosis GO:0051402 12 9 0,000 0,01439112 0,04003532 ! lens development in camera-type eye GO:0002088 11 9 0,000 0,01439112 0,03998844 ! positive regulation of vasodilation GO:0045909 14 9 0,000 0,01439112 0,03994167 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01439112 0,039895 ! positive regulation of muscle contraction GO:0045933 13 9 0,000 0,01439112 0,03984845 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01439112 0,03980201 ! regulation of smoothened signaling pathway GO:0008589 15 9 0,000 0,01439112 0,03975567 ! Schwann cell differentiation GO:0014037 20 9 0,000 0,01439112 0,03970945 ! acyl-CoA metabolic process GO:0006637 14 9 0,000 0,01439112 0,03966333 ! regulation of gliogenesis GO:0014013 21 9 0,000 0,01439112 0,03961731 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 21 9 0,000 0,01439112 0,03957141 ! oligodendrocyte development GO:0014003 13 9 0,000 0,01439112 0,03952561 ! alpha-beta T cell differentiation GO:0046632 15 9 0,000 0,01439112 0,03947991 ! segment specification GO:0007379 11 9 0,000 0,01439112 0,03943432 ! cellular extravasation GO:0045123 12 9 0,000 0,01439112 0,03938884 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01439112 0,03934346 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 13 9 0,000 0,01439112 0,03929819 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01439112 0,03925302 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01439112 0,03920795 ! antigen processing and presentation of exogenous antigen GO:0019884 11 9 0,000 0,01439112 0,03916299 ! positive regulation of production of molecular mediator of immune response GO:0002702 13 9 0,000 0,01439112 0,03911813 ! purine nucleoside triphosphate catabolic process GO:0009146 13 9 0,000 0,01439112 0,03907337 ! regulation of T cell differentiation in the thymus GO:0033081 14 9 0,000 0,01439112 0,03902871 ! response to amine stimulus GO:0014075 13 9 0,000 0,01439112 0,03898416 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of protein kinase B signaling cascade GO:0051896 16 9 0,000 0,01439112 0,03893971 ! erythrocyte development GO:0048821 13 9 0,000 0,01439112 0,03889536 ! renal water homeostasis GO:0003091 13 9 0,000 0,01439112 0,03885111 ! positive regulation of tumor necrosis factor production GO:0032760 10 9 0,000 0,01439112 0,03880696 ! nucleosome disassembly GO:0006337 13 9 0,000 0,01439112 0,03876291 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! spinal cord motor neuron differentiation GO:0021522 12 9 0,000 0,01439112 0,03871896 ! transcription from RNA polymerase I promoter GO:0006360 14 9 0,000 0,01439112 0,03867511 ! induction of an organ GO:0001759 13 9 0,000 0,01439112 0,03863136 ! leukocyte activation during immune response GO:0002366 15 9 0,000 0,01439112 0,03858771 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 11 9 0,000 0,01439112 0,03854416 ! cerebellum morphogenesis GO:0021587 13 9 0,000 0,01439112 0,0385007 GO:0021696|cerebellar cortex morphogenesis, ! retinal ganglion cell axon guidance GO:0031290 11 9 0,000 0,01439112 0,03845735 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01439112 0,03841409 ! sterol catabolic process GO:0016127 11 9 0,000 0,01439112 0,03837093 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 18 9 0,000 0,01439112 0,03832786 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01439112 0,03828489 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 14 9 0,000 0,01439112 0,03824202 ! positive regulation of interleukin-1 secretion GO:0050716 11 9 0,000 0,01439112 0,03819924 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 0,01439112 0,03815656 ! negative regulation of cytokine secretion GO:0050710 13 9 0,000 0,01439112 0,03811398 ! prophase GO:0051324 12 9 0,000 0,01439112 0,03807149 ! neuroblast proliferation GO:0007405 19 9 0,000 0,01439112 0,03802909 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 16 9 0,000 0,01439112 0,03798679 ! peptidyl-threonine modification GO:0018210 22 9 0,000 0,01439112 0,03794458 ! regulation of interleukin-1 beta secretion GO:0050706 12 9 0,000 0,01439112 0,03790247 ! ubiquinone metabolic process GO:0006743 11 9 0,000 0,01439112 0,03786045 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of erythrocyte differentiation GO:0045648 20 9 0,000 0,01439112 0,03781852 ! acid secretion GO:0046717 14 9 0,000 0,01439112 0,03777669 ! purine base metabolic process GO:0006144 18 9 0,000 0,01439112 0,03773494 ! detection of calcium ion GO:0005513 13 9 0,000 0,01439112 0,03769329 ! myeloid cell homeostasis GO:0002262 10 9 0,000 0,01439112 0,03765174 ! regulation of fibrinolysis GO:0051917 14 9 0,000 0,01439112 0,03761027 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01439112 0,03756889 ! natural killer cell mediated immunity GO:0002228 14 9 0,000 0,01439112 0,03752761 GO:0042267|natural killer cell mediated cytotoxicity, ! negative regulation of blood vessel endothelial cell migration GO:0043537 18 9 0,000 0,01439112 0,03748641 ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01439112 0,03744531 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01439112 0,0374043 ! defense response to Gram-positive bacterium GO:0050830 11 9 0,000 0,01439112 0,03736337 ! prepulse inhibition GO:0060134 14 9 0,000 0,01439112 0,03732254 ! sequestering of metal ion GO:0051238 12 9 0,000 0,01439112 0,03728179 ! lamellipodium assembly GO:0030032 12 9 0,000 0,01439112 0,03724114 ! regulation of embryonic development GO:0045995 17 9 0,000 0,01439112 0,03720057 ! mitochondrion localization GO:0051646 15 9 0,000 0,01439112 0,03716009 ! localization within membrane GO:0051668 15 9 0,000 0,01439112 0,0371197 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01597769 0,04116728 ! axon extension GO:0048675 13 10 0,000 0,01597769 0,04112263 ! neuron fate specification GO:0048665 12 10 0,000 0,01597769 0,04107807 ! regulation of epithelial cell differentiation GO:0030856 20 10 0,000 0,01597769 0,04103362 ! cortical actin cytoskeleton organization GO:0030866 24 10 0,000 0,01597769 0,04098926 ! associative learning GO:0008306 19 10 0,000 0,01597769 0,04094499 ! cellular copper ion homeostasis GO:0006878 14 10 0,000 0,01597769 0,04090082 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01597769 0,04085675 ! CTP metabolic process GO:0046036 11 10 0,000 0,01597769 0,04081277 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 17 10 0,000 0,01597769 0,04076888 ! GTP metabolic process GO:0046039 11 10 0,000 0,01597769 0,04072509 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01597769 0,0406814 GO:0007520|myoblast fusion, ! actin-myosin filament sliding GO:0033275 14 10 0,000 0,01597769 0,04063779 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01597769 0,04059428 ! social behavior GO:0035176 15 10 0,000 0,01597769 0,04055087 ! sulfate transport GO:0008272 12 10 0,000 0,01597769 0,04050754 ! regulation of activated T cell proliferation GO:0046006 22 10 0,000 0,01597769 0,04046431 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 19 10 0,000 0,01597769 0,04042117 ! artery development GO:0060840 20 10 0,000 0,01597769 0,04037813 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 13 10 0,000 0,01597769 0,04033517 ! response to pain GO:0048265 20 10 0,000 0,01597769 0,04029231 ! COPI coating of Golgi vesicle GO:0048205 15 10 0,000 0,01597769 0,04024953 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,01597769 0,04020685 ! phospholipid efflux GO:0033700 17 10 0,000 0,01597769 0,04016426 ! hippocampus development GO:0021766 19 10 0,000 0,01597769 0,04012176 ! positive regulation of transcription factor import into nucleus GO:0042993 21 10 0,000 0,01597769 0,04007935 ! amyloid precursor protein metabolic process GO:0042982 16 10 0,000 0,01597769 0,04003702 ! blood vessel remodeling GO:0001974 23 10 0,000 0,01597769 0,03999479 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01597769 0,03995265 ! pathogenesis GO:0009405 13 10 0,000 0,01597769 0,03991059 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01597769 0,03986862 ! two-component signal transduction system (phosphorelay) GO:0000160 15 10 0,000 0,01597769 0,03982675 ! negative regulation of striated muscle development GO:0045843 13 10 0,000 0,01597769 0,03978495 ! protein targeting to ER GO:0045047 21 10 0,000 0,01597769 0,03974325 ! regulation of S phase of mitotic cell cycle GO:0007090 19 10 0,000 0,01597769 0,03970164 ! arginine catabolic process GO:0006527 12 10 0,000 0,01597769 0,03966011 ! melanocyte differentiation GO:0030318 16 10 0,000 0,01597769 0,03961866 GO:0050931|pigment cell differentiation, ! telomere maintenance via telomerase GO:0007004 14 10 0,000 0,01597769 0,03957731 GO:0010833|telomere maintenance via telomere lengthening, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01597769 0,03953604 ! regulation of phosphoprotein phosphatase activity GO:0043666 20 10 0,000 0,01597769 0,03949486 ! regulation of stress fiber formation GO:0051492 24 10 0,000 0,01597769 0,03945376 ! positive regulation of endothelial cell migration GO:0010595 20 10 0,000 0,01597769 0,03941275 ! B cell proliferation GO:0042100 16 10 0,000 0,01597769 0,03937182 ! nucleobase biosynthetic process GO:0046112 20 10 0,000 0,01597769 0,03933098 ! mannose metabolic process GO:0006013 11 10 0,000 0,01597769 0,03929022 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01597769 0,03924955 ! forebrain cell migration GO:0021885 17 10 0,000 0,01597769 0,03920896 ! lipid digestion GO:0044241 15 10 0,000 0,01597769 0,03916845 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01597769 0,03912803 ! receptor clustering GO:0043113 18 10 0,000 0,01597769 0,03908769 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01597769 0,03904744 ! UV protection GO:0009650 14 10 0,000 0,01597769 0,03900726 ! entry into host cell GO:0030260 21 10 0,000 0,01597769 0,03896718 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of lipoprotein lipase activity GO:0051004 20 10 0,000 0,01597769 0,03892717 ! behavioral fear response GO:0001662 19 10 0,000 0,01597769 0,03888724 GO:0002209|behavioral defense response, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01597769 0,0388474 ! negative regulation of ossification GO:0030279 21 10 0,000 0,01597769 0,03880764 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 23 10 0,000 0,01597769 0,03876796 ! protein homotetramerization GO:0051289 20 10 0,000 0,01597769 0,03872836 ! positive regulation of peptide secretion GO:0002793 16 10 0,000 0,01597769 0,03868884 ! response to dsRNA GO:0043331 19 10 0,000 0,01597769 0,0386494 ! phosphoinositide 3-kinase cascade GO:0014065 26 10 0,000 0,01597769 0,03861004 ! regulation of interleukin-4 production GO:0032673 18 10 0,000 0,01597769 0,03857076 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01597769 0,03853157 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01597769 0,03849245 ! positive regulation of Ras GTPase activity GO:0032320 24 10 0,000 0,01597769 0,03845341 ! postreplication repair GO:0006301 16 10 0,000 0,01597769 0,03841445 ! fucose catabolic process GO:0019317 17 10 0,000 0,01597769 0,03837557 GO:0042355|L-fucose catabolic process, ! mRNA cleavage GO:0006379 14 10 0,000 0,01597769 0,03833677 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01597769 0,03829804 ! hindbrain morphogenesis GO:0021575 16 10 0,000 0,01597769 0,0382594 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 10 0,000 0,01597769 0,03822083 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 13 10 0,000 0,01597769 0,03818234 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01597769 0,03814393 ! positive regulation of neuron differentiation GO:0045666 13 10 0,000 0,01597769 0,03810559 ! positive regulation of leukocyte migration GO:0002687 24 10 0,000 0,01597769 0,03806733 ! multicellular organismal water homeostasis GO:0050891 14 10 0,000 0,01597769 0,03802915 ! negative regulation of lymphocyte differentiation GO:0045620 13 10 0,000 0,01597769 0,03799104 ! methionine biosynthetic process GO:0009086 13 10 0,000 0,01597769 0,03795301 ! oocyte differentiation GO:0009994 14 10 0,000 0,01597769 0,03791506 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 14 10 0,000 0,01597769 0,03787718 ! spleen development GO:0048536 17 10 0,000 0,01597769 0,03783938 ! negative regulation of BMP signaling pathway GO:0030514 15 10 0,000 0,01597769 0,03780166 ! regulation of RNA splicing GO:0043484 15 10 0,000 0,01597769 0,03776401 ! blastocyst formation GO:0001825 14 10 0,000 0,01597769 0,03772643 ! embryonic gut development GO:0048566 13 10 0,000 0,01597769 0,03768893 ! quinone cofactor metabolic process GO:0042375 12 10 0,000 0,01597769 0,0376515 ! cerebellar cortex development GO:0021695 14 10 0,000 0,01597769 0,03761415 ! activation of innate immune response GO:0002218 10 10 0,000 0,01597769 0,03757687 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01597769 0,03753966 ! insulin secretion GO:0030073 18 10 0,000 0,01597769 0,03750253 ! cytoplasmic sequestering of protein GO:0051220 15 10 0,000 0,01597769 0,03746548 ! response to nicotine GO:0035094 18 10 0,000 0,01597769 0,03742849 ! establishment of cell polarity GO:0030010 12 10 0,000 0,01597769 0,03739158 ! nucleus localization GO:0051647 16 10 0,000 0,01597769 0,03735474 ! regulation of synapse organization GO:0050807 14 10 0,000 0,01597769 0,03731797 ! negative regulation of muscle development GO:0048635 14 11 0,000 0,01756179 0,04097751 ! positive regulation of glucose metabolic process GO:0010907 17 11 0,000 0,01756179 0,04093726 ! ER-associated protein catabolic process GO:0030433 17 11 0,000 0,01756179 0,04089708 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of blood pressure GO:0045776 25 11 0,000 0,01756179 0,04085699 ! cortical cytoskeleton organization GO:0030865 25 11 0,000 0,01756179 0,04081697 ! virus-host interaction GO:0019048 20 11 0,000 0,01756179 0,04077703 ! thyroid gland development GO:0030878 20 11 0,000 0,01756179 0,04073717 ! pentose-phosphate shunt GO:0006098 14 11 0,000 0,01756179 0,04069739 GO:0006740|NADPH regeneration, ! regulation of phosphatase activity GO:0010921 23 11 0,000 0,01756179 0,04065769 ! non-recombinational repair GO:0000726 19 11 0,000 0,01756179 0,04061806 GO:0006303|double-strand break repair via nonhomologous end joining, ! synapsis GO:0007129 15 11 0,000 0,01756179 0,04057851 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 11 11 0,000 0,01756179 0,04053903 ! Golgi vesicle budding GO:0048194 18 11 0,000 0,01756179 0,04049964 ! elastic fiber assembly GO:0048251 17 11 0,000 0,01756179 0,04046032 ! regulation of positive chemotaxis GO:0050926 19 11 0,000 0,01756179 0,04042107 GO:0050927|positive regulation of positive chemotaxis, ! regulation of glycolysis GO:0006110 18 11 0,000 0,01756179 0,04038191 ! dopamine receptor signaling pathway GO:0007212 25 11 0,000 0,01756179 0,04034281 ! regulation of cell projection assembly GO:0060491 22 11 0,000 0,01756179 0,0403038 ! positive regulation of lipid metabolic process GO:0045834 15 11 0,000 0,01756179 0,04026486 ! bone resorption GO:0045453 16 11 0,000 0,01756179 0,04022599 ! regulation of chemokine biosynthetic process GO:0045073 13 11 0,000 0,01756179 0,0401872 ! peptide or protein amino-terminal blocking GO:0018409 16 11 0,000 0,01756179 0,04014849 ! ventral spinal cord development GO:0021517 15 11 0,000 0,01756179 0,04010984 ! regulated secretory pathway GO:0045055 15 11 0,000 0,01756179 0,04007128 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 19 11 0,000 0,01756179 0,04003278 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! regulation of catecholamine secretion GO:0050433 21 11 0,000 0,01756179 0,03999436 ! syncytium formation GO:0006949 15 11 0,000 0,01756179 0,03995602 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01756179 0,03991775 ! glucan biosynthetic process GO:0009250 14 11 0,000 0,01756179 0,03987955 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 16 11 0,000 0,01756179 0,03984142 ! Golgi organization GO:0007030 19 11 0,000 0,01756179 0,03980337 ! response to X-ray GO:0010165 19 11 0,000 0,01756179 0,03976539 ! retinoic acid receptor signaling pathway GO:0048384 16 11 0,000 0,01756179 0,03972748 ! adult heart development GO:0007512 12 11 0,000 0,01756179 0,03968965 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01756179 0,03965188 ! epithelial cell development GO:0002064 16 11 0,000 0,01756179 0,03961419 ! actin cytoskeleton reorganization GO:0031532 20 11 0,000 0,01756179 0,03957657 ! temperature homeostasis GO:0001659 16 11 0,000 0,01756179 0,03953902 ! L-glutamate transport GO:0015813 15 11 0,000 0,01756179 0,03950154 GO:0015800|acidic amino acid transport, ! positive regulation vascular endothelial growth factor production GO:0010575 19 11 0,000 0,01756179 0,03946414 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01756179 0,0394268 ! motor axon guidance GO:0008045 17 11 0,000 0,01756179 0,03938953 ! copper ion homeostasis GO:0055070 15 11 0,000 0,01756179 0,03935234 ! protein targeting to peroxisome GO:0006625 21 11 0,000 0,01756179 0,03931521 ! regulation of bone resorption GO:0045124 27 11 0,000 0,01756179 0,03927816 ! stem cell development GO:0048864 30 11 0,000 0,01756179 0,03924117 GO:0019827|stem cell maintenance, ! alpha-beta T cell activation GO:0046631 18 11 0,000 0,01756179 0,03920426 ! negative regulation of axonogenesis GO:0050771 26 11 0,000 0,01756179 0,03916741 ! regulation of phagocytosis GO:0050764 16 11 0,000 0,01756179 0,03913064 ! regulation of insulin receptor signaling pathway GO:0046626 17 11 0,000 0,01756179 0,03909393 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01756179 0,03905729 ! nucleoside triphosphate catabolic process GO:0009143 16 11 0,000 0,01756179 0,03902072 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01756179 0,03898422 ! synaptic vesicle exocytosis GO:0016079 16 11 0,000 0,01756179 0,03894778 ! regulation of B cell differentiation GO:0045577 23 11 0,000 0,01756179 0,03891142 ! cranial nerve development GO:0021545 14 11 0,000 0,01756179 0,03887512 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01756179 0,03883889 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01756179 0,03880273 ! salivary gland development GO:0007431 24 11 0,000 0,01756179 0,03876663 ! negative regulation of neurological system process GO:0031645 20 11 0,000 0,01756179 0,0387306 ! regulation of leukocyte migration GO:0002685 25 11 0,000 0,01756179 0,03869464 ! musculoskeletal movement GO:0050881 16 11 0,000 0,01756179 0,03865875 GO:0050879|multicellular organismal movement, ! nitric oxide mediated signal transduction GO:0007263 20 11 0,000 0,01756179 0,03862292 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01756179 0,03858716 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01756179 0,03855146 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 19 11 0,000 0,01756179 0,03851583 ! cholesterol efflux GO:0033344 20 11 0,000 0,01756179 0,03848027 ! digestive tract morphogenesis GO:0048546 16 11 0,000 0,01756179 0,03844477 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 11 0,000 0,01756179 0,03840933 ! thyroid hormone metabolic process GO:0042403 17 11 0,000 0,01756179 0,03837397 ! leukocyte mediated cytotoxicity GO:0001909 18 11 0,000 0,01756179 0,03833866 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01756179 0,03830343 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 21 11 0,000 0,01756179 0,03826825 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01756179 0,03823314 ! regulation of actin filament bundle formation GO:0032231 25 11 0,000 0,01756179 0,0381981 ! cardiac cell differentiation GO:0035051 18 11 0,000 0,01756179 0,03816312 ! defense response to fungus GO:0050832 13 11 0,000 0,01756179 0,0381282 ! lysogeny GO:0030069 20 11 0,000 0,01756179 0,03809335 GO:0019047|provirus integration, ! T cell receptor signaling pathway GO:0050852 22 11 0,000 0,01756179 0,03805856 ! acrosome reaction GO:0007340 14 11 0,000 0,01756179 0,03802384 ! regulation of synapse structure and activity GO:0050803 15 11 0,000 0,01756179 0,03798918 ! regulation of steroid biosynthetic process GO:0050810 13 11 0,000 0,01756179 0,03795458 ! rRNA transcription GO:0009303 19 12 0,000 0,01914342 0,04133515 ! reproductive cellular process GO:0048610 15 12 0,000 0,01914342 0,04129757 ! regulation of membrane protein ectodomain proteolysis GO:0051043 17 12 0,000 0,01914342 0,04126006 ! pteridine and derivative biosynthetic process GO:0042559 15 12 0,000 0,01914342 0,04122262 ! dicarboxylic acid transport GO:0006835 21 12 0,000 0,01914342 0,04118525 ! phosphate transport GO:0006817 15 12 0,000 0,01914342 0,04114794 ! positive regulation of GTPase activity GO:0043547 29 12 0,000 0,01914342 0,04111071 ! peroxisomal transport GO:0043574 22 12 0,000 0,01914342 0,04107354 ! mating GO:0007618 16 12 0,000 0,01914342 0,04103643 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01914342 0,0409994 ! heart looping GO:0001947 15 12 0,000 0,01914342 0,04096243 ! negative regulation of cell-matrix adhesion GO:0001953 31 12 0,000 0,01914342 0,04092552 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 20 12 0,000 0,01914342 0,04088869 ! negative regulation of proteolysis GO:0045861 17 12 0,000 0,01914342 0,04085192 ! T cell selection GO:0045058 25 12 0,000 0,01914342 0,04081521 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01914342 0,04077857 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 17 12 0,000 0,01914342 0,040742 ! oligodendrocyte differentiation GO:0048709 19 12 0,000 0,01914342 0,04070549 ! plasma membrane organization GO:0007009 19 12 0,000 0,01914342 0,04066905 ! focal adhesion formation GO:0048041 28 12 0,000 0,01914342 0,04063268 ! mitotic spindle organization GO:0007052 16 12 0,000 0,01914342 0,04059636 ! cellular carbohydrate catabolic process GO:0044275 14 12 0,000 0,01914342 0,04056012 ! regulation of intracellular pH GO:0051453 19 12 0,000 0,01914342 0,04052394 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01914342 0,04048782 ! monoamine transport GO:0015844 14 12 0,000 0,01914342 0,04045176 ! regulation of vascular endothelial growth factor production GO:0010574 20 12 0,000 0,01914342 0,04041578 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 18 12 0,000 0,01914342 0,04037985 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01914342 0,04034399 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01914342 0,04030819 ! regulation of organ growth GO:0046620 14 12 0,000 0,01914342 0,04027246 ! vasoconstriction GO:0042310 18 12 0,000 0,01914342 0,04023679 ! RNA-dependent DNA replication GO:0006278 16 12 0,000 0,01914342 0,04020118 ! regulation of interleukin-8 production GO:0032677 19 12 0,000 0,01914342 0,04016563 ! regulation of Rho GTPase activity GO:0032319 22 12 0,000 0,01914342 0,04013015 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01914342 0,04009473 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01914342 0,04005938 ! histone deacetylation GO:0016575 14 12 0,000 0,01914342 0,04002408 ! histone acetylation GO:0016573 27 12 0,000 0,01914342 0,03998885 ! DNA methylation GO:0006306 19 12 0,000 0,01914342 0,03995368 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 19 12 0,000 0,01914342 0,03991857 ! protein sumoylation GO:0016925 14 12 0,000 0,01914342 0,03988352 ! chromatin silencing GO:0006342 23 12 0,000 0,01914342 0,03984854 ! negative regulation of MAPKKK cascade GO:0043409 23 12 0,000 0,01914342 0,03981361 ! gland morphogenesis GO:0022612 24 12 0,000 0,01914342 0,03977875 ! regulation of hormone metabolic process GO:0032350 21 12 0,000 0,01914342 0,03974395 ! zymogen activation GO:0031638 16 12 0,000 0,01914342 0,03970921 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01914342 0,03967453 ! nucleosome positioning GO:0016584 13 12 0,000 0,01914342 0,03963991 ! T cell homeostasis GO:0043029 22 12 0,000 0,01914342 0,03960535 ! regulation of isotype switching GO:0045191 22 12 0,000 0,01914342 0,03957085 ! glutathione biosynthetic process GO:0006750 14 12 0,000 0,01914342 0,03953641 ! response to gamma radiation GO:0010332 21 12 0,000 0,01914342 0,03950203 ! regulation of osteoclast differentiation GO:0045670 18 12 0,000 0,01914342 0,03946771 ! regulation of T-helper 2 cell differentiation GO:0045628 19 12 0,000 0,01914342 0,03943345 ! aromatic amino acid family catabolic process GO:0009074 16 12 0,000 0,01914342 0,03939925 ! serine family amino acid biosynthetic process GO:0009070 16 12 0,000 0,01914342 0,03936511 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01914342 0,03933102 ! male genitalia development GO:0030539 15 12 0,000 0,01914342 0,039297 ! regulation of cellular carbohydrate catabolic process GO:0043471 19 12 0,000 0,01914342 0,03926303 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of fatty acid oxidation GO:0046320 20 12 0,000 0,01914342 0,03922913 ! establishment or maintenance of apical/basal cell polarity GO:0035088 23 12 0,000 0,01914342 0,03919528 ! developmental induction GO:0031128 16 12 0,000 0,01914342 0,03916149 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 15 12 0,000 0,01914342 0,03912776 ! response to cold GO:0009409 15 12 0,000 0,01914342 0,03909409 ! negative regulation of immune effector process GO:0002698 20 12 0,000 0,01914342 0,03906047 ! respiratory burst GO:0045730 22 13 0,000 0,02072258 0,04224629 ! lactation GO:0007595 22 13 0,000 0,02072258 0,04221003 ! tRNA modification GO:0006400 15 13 0,000 0,02072258 0,04217383 ! negative regulation of cell projection organization GO:0031345 29 13 0,000 0,02072258 0,04213769 ! positive regulation of blood pressure GO:0045777 19 13 0,000 0,02072258 0,04210161 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02072258 0,0420656 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 20 13 0,000 0,02072258 0,04202964 ! water transport GO:0006833 21 13 0,000 0,02072258 0,04199375 GO:0042044|fluid transport, ! regulation of nitric-oxide synthase activity GO:0050999 23 13 0,000 0,02072258 0,04195792 ! copper ion transport GO:0006825 15 13 0,000 0,02072258 0,04192215 ! filopodium assembly GO:0046847 21 13 0,000 0,02072258 0,04188644 ! lipid localization GO:0010876 25 13 0,000 0,02072258 0,04185079 GO:0019915|lipid storage, ! detection of mechanical stimulus GO:0050982 17 13 0,000 0,02072258 0,04181521 ! negative regulation of transcription factor import into nucleus GO:0042992 26 13 0,000 0,02072258 0,04177968 ! cytokine biosynthetic process GO:0042089 17 13 0,000 0,02072258 0,04174421 ! T cell proliferation GO:0042098 24 13 0,000 0,02072258 0,04170881 ! organelle fusion GO:0048284 29 13 0,000 0,02072258 0,04167346 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02072258 0,04163817 ! endocrine pancreas development GO:0031018 19 13 0,000 0,02072258 0,04160295 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 24 13 0,000 0,02072258 0,04156778 ! platelet-derived growth factor receptor signaling pathway GO:0048008 20 13 0,000 0,02072258 0,04153267 ! photoreceptor cell maintenance GO:0045494 20 13 0,000 0,02072258 0,04149762 ! regulation of mRNA processing GO:0050684 21 13 0,000 0,02072258 0,04146263 ! regulation of skeletal muscle fiber development GO:0048742 22 13 0,000 0,02072258 0,0414277 ! methionine metabolic process GO:0006555 16 13 0,000 0,02072258 0,04139283 ! deoxyribonucleotide catabolic process GO:0009264 17 13 0,000 0,02072258 0,04135802 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02072258 0,04132326 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 21 13 0,000 0,02072258 0,04128857 ! negative regulation of endothelial cell migration GO:0010596 22 13 0,000 0,02072258 0,04125393 ! membrane protein proteolysis GO:0033619 21 13 0,000 0,02072258 0,04121935 GO:0006509|membrane protein ectodomain proteolysis, ! fear response GO:0042596 22 13 0,000 0,02072258 0,04118483 ! neutral amino acid transport GO:0015804 20 13 0,000 0,02072258 0,04115036 ! negative regulation of mitotic cell cycle GO:0045930 32 13 0,000 0,02072258 0,04111595 ! regulation of natural killer cell mediated immunity GO:0002715 21 13 0,000 0,02072258 0,0410816 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 16 13 0,000 0,02072258 0,04104731 ! positive regulation of protein import into nucleus GO:0042307 24 13 0,000 0,02072258 0,04101308 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02072258 0,0409789 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02072258 0,04094478 ! cellular pigmentation GO:0033059 24 13 0,000 0,02072258 0,04091072 ! histone methylation GO:0016571 16 13 0,000 0,02072258 0,04087671 ! regulation of epidermis development GO:0045682 21 13 0,000 0,02072258 0,04084276 ! oxygen transport GO:0015671 20 13 0,000 0,02072258 0,04080886 ! regulation of axon extension GO:0030516 26 13 0,000 0,02072258 0,04077503 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 24 13 0,000 0,02072258 0,04074124 ! detection of bacterium GO:0016045 13 13 0,000 0,02072258 0,04070752 ! L-fucose metabolic process GO:0042354 21 13 0,000 0,02072258 0,04067385 ! regulation of NF-kappaB import into nucleus GO:0042345 24 13 0,000 0,02072258 0,04064023 ! positive regulation of homeostatic process GO:0032846 19 13 0,000 0,02072258 0,04060667 ! positive regulation of protein polymerization GO:0032273 21 13 0,000 0,02072258 0,04057317 ! actin filament polymerization GO:0030041 18 13 0,000 0,02072258 0,04053972 ! regulation of protein ubiquitination GO:0031396 20 14 0,000 0,02229928 0,04358829 ! N-terminal protein amino acid modification GO:0031365 20 14 0,000 0,02229928 0,04355242 ! positive regulation of cellular catabolic process GO:0031331 24 14 0,000 0,02229928 0,0435166 ! G1 phase of mitotic cell cycle GO:0000080 24 14 0,000 0,02229928 0,04348084 ! neuron maturation GO:0042551 24 14 0,000 0,02229928 0,04344514 ! regulation of S phase GO:0033261 25 14 0,000 0,02229928 0,0434095 ! regulation of chemokine production GO:0032642 18 14 0,000 0,02229928 0,04337392 ! myotube differentiation GO:0014902 21 14 0,000 0,02229928 0,0433384 ! double-strand break repair via homologous recombination GO:0000724 24 14 0,000 0,02229928 0,04330293 GO:0000725|recombinational repair, ! negative regulation of bone remodeling GO:0046851 28 14 0,000 0,02229928 0,04326753 ! phospholipid catabolic process GO:0009395 19 14 0,000 0,02229928 0,04323218 ! aminoglycan catabolic process GO:0006026 19 14 0,000 0,02229928 0,04319689 ! vesicle targeting, to, from or within Golgi GO:0048199 19 14 0,000 0,02229928 0,04316165 ! cardiac muscle contraction GO:0060048 28 14 0,000 0,02229928 0,04312648 ! RNA polyadenylation GO:0043631 21 14 0,000 0,02229928 0,04309136 ! cartilage condensation GO:0001502 22 14 0,000 0,02229928 0,04305629 ! gene silencing by RNA GO:0031047 22 14 0,000 0,02229928 0,04302129 ! response to cAMP GO:0051591 20 14 0,000 0,02229928 0,04298634 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 17 14 0,000 0,02229928 0,04295145 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 14 0,000 0,02229928 0,04291661 ! negative regulation of cytokine biosynthetic process GO:0042036 19 14 0,000 0,02229928 0,04288184 ! limbic system development GO:0021761 25 14 0,000 0,02229928 0,04284711 ! positive regulation of ion transport GO:0043270 18 14 0,000 0,02229928 0,04281245 GO:0051928|positive regulation of calcium ion transport, ! startle response GO:0001964 21 14 0,000 0,02229928 0,04277784 ! palate development GO:0060021 19 14 0,000 0,02229928 0,04274328 ! negative regulation of gene expression, epigenetic GO:0045814 30 14 0,000 0,02229928 0,04270879 ! negative regulation of protein amino acid phosphorylation GO:0001933 31 14 0,000 0,02229928 0,04267434 ! regulation of defense response to virus GO:0050688 26 14 0,000 0,02229928 0,04263996 ! response to hexose stimulus GO:0009746 22 14 0,000 0,02229928 0,04260562 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! epidermis morphogenesis GO:0048730 31 14 0,000 0,02229928 0,04257135 ! arginine metabolic process GO:0006525 17 14 0,000 0,02229928 0,04253713 ! glutamate metabolic process GO:0006536 21 14 0,000 0,02229928 0,04250296 ! glycine metabolic process GO:0006544 22 14 0,000 0,02229928 0,04246885 ! pituitary gland development GO:0021983 24 14 0,000 0,02229928 0,04243479 ! tyrosine metabolic process GO:0006570 20 14 0,000 0,02229928 0,04240079 ! negative regulation of microtubule depolymerization GO:0007026 34 14 0,000 0,02229928 0,04236684 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 21 14 0,000 0,02229928 0,04233295 ! cytokine metabolic process GO:0042107 18 14 0,000 0,02229928 0,04229911 ! NAD metabolic process GO:0019674 25 14 0,000 0,02229928 0,04226532 ! regulation of ion transmembrane transporter activity GO:0032412 19 14 0,000 0,02229928 0,04223159 ! regulation of heart rate GO:0002027 26 14 0,000 0,02229928 0,04219792 ! exocrine system development GO:0035272 29 14 0,000 0,02229928 0,04216429 ! positive regulation of carbohydrate metabolic process GO:0045913 22 14 0,000 0,02229928 0,04213072 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! purine nucleoside monophosphate metabolic process GO:0009126 22 14 0,000 0,02229928 0,0420972 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 25 14 0,000 0,02229928 0,04206374 ! axon cargo transport GO:0008088 29 14 0,000 0,02229928 0,04203033 ! positive regulation of T cell mediated immunity GO:0002711 30 14 0,000 0,02229928 0,04199697 ! negative regulation of protein import into nucleus GO:0042308 27 14 0,000 0,02229928 0,04196367 ! genitalia development GO:0048806 18 14 0,000 0,02229928 0,04193042 ! regulation of interleukin-12 production GO:0032655 20 14 0,000 0,02229928 0,04189722 ! autonomic nervous system development GO:0048483 26 14 0,000 0,02229928 0,04186407 ! tissue regeneration GO:0042246 24 14 0,000 0,02229928 0,04183098 ! negative regulation of protein secretion GO:0050709 22 14 0,000 0,02229928 0,04179794 ! water homeostasis GO:0030104 23 14 0,000 0,02229928 0,04176495 ! cofactor transport GO:0051181 22 14 0,000 0,02229928 0,04173201 ! regulation of acute inflammatory response GO:0002673 21 14 0,000 0,02229928 0,04169912 ! positive regulation of T-helper cell differentiation GO:0045624 20 14 0,000 0,02229928 0,04166629 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,02229928 0,04163351 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,02229928 0,04160078 ! regulation of mRNA stability GO:0043488 30 14 0,000 0,02229928 0,0415681 ! cell killing GO:0001906 22 14 0,000 0,02229928 0,04153547 ! positive regulation of JNK cascade GO:0046330 22 14 0,000 0,02229928 0,04150289 ! epithelial to mesenchymal transition GO:0001837 24 14 0,000 0,02229928 0,04147037 ! negative regulation of mast cell proliferation GO:0070667 26 14 0,000 0,02229928 0,04143789 GO:0042130|negative regulation of T cell proliferation, ! mRNA 3'-end processing GO:0031124 21 14 0,000 0,02229928 0,04140547 ! microspike assembly GO:0030035 25 14 0,000 0,02229928 0,04137309 ! positive regulation of calcium-mediated signaling GO:0050850 27 14 0,000 0,02229928 0,04134077 ! regulation of skeletal muscle tissue development GO:0048641 24 15 0,000 0,02387352 0,04422471 ! superoxide anion generation GO:0042554 19 15 0,000 0,02387352 0,04419021 ! negative regulation of hormone secretion GO:0046888 22 15 0,000 0,02387352 0,04415577 ! embryonic hindlimb morphogenesis GO:0035116 28 15 0,000 0,02387352 0,04412138 ! embryonic forelimb morphogenesis GO:0035115 18 15 0,000 0,02387352 0,04408705 ! inositol metabolic process GO:0006020 21 15 0,000 0,02387352 0,04405276 ! retina development in camera-type eye GO:0060041 22 15 0,000 0,02387352 0,04401854 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 22 15 0,000 0,02387352 0,04398436 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 25 15 0,000 0,02387352 0,04395024 ! regulation of transmembrane transporter activity GO:0022898 20 15 0,000 0,02387352 0,04391617 GO:0032409|regulation of transporter activity, ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02387352 0,04388215 ! activation of MAPKK activity GO:0000186 22 15 0,000 0,02387352 0,04384818 ! induction of apoptosis via death domain receptors GO:0008625 19 15 0,000 0,02387352 0,04381427 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 18 15 0,000 0,02387352 0,04378041 ! response to osmotic stress GO:0006970 23 15 0,000 0,02387352 0,04374661 ! vesicle coating GO:0006901 26 15 0,000 0,02387352 0,04371285 ! regulation of the force of heart contraction GO:0002026 24 15 0,000 0,02387352 0,04367915 ! preassembly of GPI anchor in ER membrane GO:0016254 22 15 0,000 0,02387352 0,0436455 ! positive regulation of activation of JAK2 kinase activity GO:0010535 15 15 0,000 0,02387352 0,0436119 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 23 15 0,000 0,02387352 0,04357835 ! bone mineralization GO:0030282 17 15 0,000 0,02387352 0,04354485 ! G1/S transition checkpoint GO:0031575 36 15 0,000 0,02387352 0,04351141 ! intermediate filament cytoskeleton organization GO:0045104 27 15 0,000 0,02387352 0,04347802 ! positive regulation of axonogenesis GO:0050772 21 15 0,000 0,02387352 0,04344467 ! regulation of cytokine production during immune response GO:0002718 23 15 0,000 0,02387352 0,04341138 ! T cell differentiation in the thymus GO:0033077 30 15 0,000 0,02387352 0,04337814 ! regulation of cellular pH GO:0030641 23 15 0,000 0,02387352 0,04334495 ! ribosome assembly GO:0042255 17 15 0,000 0,02387352 0,04331182 ! cerebellum development GO:0021549 19 15 0,000 0,02387352 0,04327873 ! regulation of monooxygenase activity GO:0032768 29 15 0,000 0,02387352 0,04324569 ! mRNA splice site selection GO:0006376 33 15 0,000 0,02387352 0,0432127 ! positive regulation of cytokine secretion GO:0050715 19 15 0,000 0,02387352 0,04317977 ! regulation of T-helper 2 type immune response GO:0002828 24 15 0,000 0,02387352 0,04314688 ! negative regulation of inflammatory response GO:0050728 18 15 0,000 0,02387352 0,04311404 ! sphingolipid catabolic process GO:0030149 27 15 0,000 0,02387352 0,04308126 GO:0046466|membrane lipid catabolic process, ! positive regulation of bone mineralization GO:0030501 22 15 0,000 0,02387352 0,04304852 ! regulation of erythrocyte differentiation GO:0045646 29 15 0,000 0,02387352 0,04301584 ! muscle maintenance GO:0046716 21 15 0,000 0,02387352 0,0429832 ! C21-steroid hormone biosynthetic process GO:0006700 17 15 0,000 0,02387352 0,04295061 ! activation of NF-kappaB-inducing kinase activity GO:0007250 23 15 0,000 0,02387352 0,04291807 ! intestinal absorption GO:0050892 22 15 0,000 0,02387352 0,04288558 ! regulation of ATPase activity GO:0043462 24 15 0,000 0,02387352 0,04285314 ! dopamine metabolic process GO:0042417 32 15 0,000 0,02387352 0,04282075 ! gas transport GO:0015669 23 15 0,000 0,02387352 0,04278841 ! regulation of RNA stability GO:0043487 31 15 0,000 0,02387352 0,04275612 ! organic cation transport GO:0015695 19 15 0,000 0,02387352 0,04272387 ! heme biosynthetic process GO:0006783 22 15 0,000 0,02387352 0,04269168 ! regulation of BMP signaling pathway GO:0030510 24 15 0,000 0,02387352 0,04265953 ! lymphocyte homeostasis GO:0002260 29 15 0,000 0,02387352 0,04262743 ! aromatic compound biosynthetic process GO:0019438 18 15 0,000 0,02387352 0,04259538 ! cilium assembly GO:0042384 22 15 0,000 0,02387352 0,04256338 ! regulation of calcium-mediated signaling GO:0050848 28 15 0,000 0,02387352 0,04253142 ! inner ear receptor cell differentiation GO:0060113 30 15 0,000 0,02387352 0,04249952 ! peptide hormone processing GO:0016486 23 15 0,000 0,02387352 0,04246766 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 36 15 0,000 0,02387352 0,04243585 ! sulfur amino acid biosynthetic process GO:0000097 21 16 0,000 0,0254453 0,04519588 ! bone remodeling GO:0046849 24 16 0,000 0,0254453 0,04516208 ! negative regulation of nucleocytoplasmic transport GO:0046823 29 16 0,000 0,0254453 0,04512832 ! positive regulation of nucleocytoplasmic transport GO:0046824 28 16 0,000 0,0254453 0,04509462 ! regulation of cell-cell adhesion GO:0022407 38 16 0,000 0,0254453 0,04506097 ! bile acid metabolic process GO:0008206 23 16 0,000 0,0254453 0,04502736 ! axis specification GO:0009798 26 16 0,000 0,0254453 0,04499381 ! negative regulation of endothelial cell proliferation GO:0001937 33 16 0,000 0,0254453 0,04496031 ! mitotic chromosome condensation GO:0007076 26 16 0,000 0,0254453 0,04492686 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,0254453 0,04489345 ! centrosome cycle GO:0007098 18 16 0,000 0,0254453 0,0448601 ! cell differentiation in spinal cord GO:0021515 24 16 0,000 0,0254453 0,0448268 ! regulation of survival gene product expression GO:0045884 23 16 0,000 0,0254453 0,04479354 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 16 0,000 0,0254453 0,04476034 ! cellular response to starvation GO:0009267 26 16 0,000 0,0254453 0,04472718 ! DNA integration GO:0015074 25 16 0,000 0,0254453 0,04469408 ! branching involved in ureteric bud morphogenesis GO:0001658 24 16 0,000 0,0254453 0,04466102 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 35 16 0,000 0,0254453 0,04462801 ! regulation of exocytosis GO:0017157 28 16 0,000 0,0254453 0,04459505 ! embryonic digit morphogenesis GO:0042733 20 16 0,000 0,0254453 0,04456214 ! positive regulation of biomineral formation GO:0070169 23 16 0,000 0,0254453 0,04452927 ! regulation of vasodilation GO:0042312 26 16 0,000 0,0254453 0,04449646 ! DNA replication initiation GO:0006270 26 16 0,000 0,0254453 0,04446369 ! DNA unwinding during replication GO:0006268 24 16 0,000 0,0254453 0,04443098 ! regulation of steroid metabolic process GO:0019218 23 16 0,000 0,0254453 0,04439831 ! neuron recognition GO:0008038 27 16 0,000 0,0254453 0,04436568 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 22 16 0,000 0,0254453 0,04433311 ! DNA fragmentation involved in apoptosis GO:0006309 20 16 0,000 0,0254453 0,04430058 ! G1 phase GO:0051318 28 16 0,000 0,0254453 0,04426811 ! cellular amino acid derivative catabolic process GO:0042219 31 16 0,000 0,0254453 0,04423567 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,0254453 0,04420329 GO:0006626|protein targeting to mitochondrion, ! positive regulation of oxidoreductase activity GO:0051353 22 16 0,000 0,0254453 0,04417096 ! negative regulation of blood coagulation GO:0030195 21 16 0,000 0,0254453 0,04413867 ! negative regulation of tissue remodeling GO:0034104 35 16 0,000 0,0254453 0,04410643 ! NADP metabolic process GO:0006739 22 16 0,000 0,0254453 0,04407423 ! neuromuscular synaptic transmission GO:0007274 31 16 0,000 0,0254453 0,04404208 ! synaptic transmission, cholinergic GO:0007271 24 16 0,000 0,0254453 0,04400998 ! folic acid and derivative metabolic process GO:0006760 18 16 0,000 0,0254453 0,04397793 ! regulation of T-helper cell differentiation GO:0045622 25 16 0,000 0,0254453 0,04394592 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,0254453 0,04391396 ! aspartate family amino acid biosynthetic process GO:0009067 19 16 0,000 0,0254453 0,04388205 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 24 16 0,000 0,0254453 0,04385018 ! positive regulation of neuron apoptosis GO:0043525 30 16 0,000 0,0254453 0,04381836 ! regulation of blood vessel endothelial cell migration GO:0043535 37 16 0,000 0,0254453 0,04378658 ! RNA 3'-end processing GO:0031123 23 16 0,000 0,0254453 0,04375485 ! defense response to virus GO:0051607 28 16 0,000 0,0254453 0,04372317 ! peptide hormone secretion GO:0030072 26 16 0,000 0,0254453 0,04369153 ! positive regulation of protein complex assembly GO:0031334 26 17 0,000 0,02701463 0,04635265 ! regulation of lipid biosynthetic process GO:0046890 22 17 0,000 0,02701463 0,04631916 ! negative regulation of cell cycle process GO:0010948 37 17 0,000 0,02701463 0,04628572 ! zinc ion transport GO:0006829 22 17 0,000 0,02701463 0,04625232 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02701463 0,04621898 ! protein amino acid deacetylation GO:0006476 23 17 0,000 0,02701463 0,04618568 ! heterophilic cell adhesion GO:0007157 38 17 0,000 0,02701463 0,04615243 ! protein amino acid acetylation GO:0006473 33 17 0,000 0,02701463 0,04611922 ! regulation of neurotransmitter secretion GO:0046928 32 17 0,000 0,02701463 0,04608607 ! forelimb morphogenesis GO:0035136 20 17 0,000 0,02701463 0,04605296 ! negative regulation of ion transport GO:0043271 19 17 0,000 0,02701463 0,0460199 ! regulation of muscle cell differentiation GO:0051147 26 17 0,000 0,02701463 0,04598689 ! adult walking behavior GO:0007628 30 17 0,000 0,02701463 0,04595392 ! patterning of blood vessels GO:0001569 27 17 0,000 0,02701463 0,045921 ! mechanoreceptor differentiation GO:0042490 32 17 0,000 0,02701463 0,04588813 ! cellular response to hydrogen peroxide GO:0070301 25 17 0,000 0,02701463 0,04585531 GO:0042744|hydrogen peroxide catabolic process, ! retinoid metabolic process GO:0001523 22 17 0,000 0,02701463 0,04582253 GO:0016101|diterpenoid metabolic process, ! positive regulation of proteolysis GO:0045862 21 17 0,000 0,02701463 0,0457898 ! cardiac muscle tissue development GO:0048738 27 17 0,000 0,02701463 0,04575712 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02701463 0,04572448 ! protein polyubiquitination GO:0000209 31 17 0,000 0,02701463 0,04569189 ! cerebral cortex development GO:0021987 34 17 0,000 0,02701463 0,04565934 ! complement activation, alternative pathway GO:0006957 17 17 0,000 0,02701463 0,04562685 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02701463 0,0455944 ! fructose metabolic process GO:0006000 24 17 0,000 0,02701463 0,04556199 ! membrane budding GO:0006900 30 17 0,000 0,02701463 0,04552963 ! neuromuscular junction development GO:0007528 25 17 0,000 0,02701463 0,04549732 ! L-amino acid transport GO:0015807 27 17 0,000 0,02701463 0,04546505 ! regulation of protein binding GO:0043393 29 17 0,000 0,02701463 0,04543283 ! peptide secretion GO:0002790 30 17 0,000 0,02701463 0,04540065 ! stem cell differentiation GO:0048863 40 17 0,000 0,02701463 0,04536852 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02701463 0,04533644 ! intermediate filament-based process GO:0045103 29 17 0,000 0,02701463 0,0453044 ! protein export from nucleus GO:0006611 26 17 0,000 0,02701463 0,0452724 ! nucleotide-excision repair, DNA gap filling GO:0006297 23 17 0,000 0,02701463 0,04524045 ! diencephalon development GO:0021536 27 17 0,000 0,02701463 0,04520855 ! oogenesis GO:0048477 25 17 0,000 0,02701463 0,04517669 ! long-chain fatty acid transport GO:0015909 25 17 0,000 0,02701463 0,04514487 ! peptide biosynthetic process GO:0043043 22 17 0,000 0,02701463 0,0451131 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02701463 0,04508138 GO:0046467|membrane lipid biosynthetic process, ! biomineral formation GO:0031214 21 17 0,000 0,02701463 0,0450497 ! vitamin A metabolic process GO:0006776 23 17 0,000 0,02701463 0,04501806 ! steroid catabolic process GO:0006706 24 17 0,000 0,02701463 0,04498647 ! porphyrin biosynthetic process GO:0006779 24 17 0,000 0,02701463 0,04495492 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 23 17 0,000 0,02701463 0,04492342 ! nerve development GO:0021675 20 17 0,000 0,02701463 0,04489196 ! negative regulation of homeostatic process GO:0032845 29 17 0,000 0,02701463 0,04486055 ! regulation of mitotic metaphase/anaphase transition GO:0030071 33 17 0,000 0,02701463 0,04482917 ! protein secretion GO:0009306 32 18 0,000 0,02858151 0,04739618 ! regulation of glucose metabolic process GO:0010906 25 18 0,000 0,02858151 0,04736308 ! positive regulation of cell killing GO:0031343 27 18 0,000 0,02858151 0,04733003 ! negative regulation of defense response GO:0031348 21 18 0,000 0,02858151 0,04729702 ! pteridine and derivative metabolic process GO:0042558 23 18 0,000 0,02858151 0,04726406 ! positive regulation of anti-apoptosis GO:0045768 33 18 0,000 0,02858151 0,04723115 ! metencephalon development GO:0022037 25 18 0,000 0,02858151 0,04719828 ! positive regulation of hormone secretion GO:0046887 28 18 0,000 0,02858151 0,04716546 ! hormone secretion GO:0046879 28 18 0,000 0,02858151 0,04713268 ! 2'-deoxyribonucleotide metabolic process GO:0009394 24 18 0,000 0,02858151 0,04709995 GO:0019692|deoxyribose phosphate metabolic process, ! signal complex assembly GO:0007172 32 18 0,000 0,02858151 0,04706727 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 27 18 0,000 0,02858151 0,04703463 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02858151 0,04700203 ! intra-Golgi vesicle-mediated transport GO:0006891 28 18 0,000 0,02858151 0,04696948 ! protein amino acid ADP-ribosylation GO:0006471 30 18 0,000 0,02858151 0,04693698 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02858151 0,04690452 ! transcription from RNA polymerase III promoter GO:0006383 36 18 0,000 0,02858151 0,0468721 ! regulation of postsynaptic membrane potential GO:0060078 31 18 0,000 0,02858151 0,04683973 ! glial cell development GO:0021782 31 18 0,000 0,02858151 0,04680741 ! keratinization GO:0031424 19 18 0,000 0,02858151 0,04677513 ! regulation of systemic arterial blood pressure by hormone GO:0001990 27 18 0,000 0,02858151 0,04674289 GO:0050886|endocrine process, ! myoblast differentiation GO:0045445 31 18 0,000 0,02858151 0,0467107 ! inactivation of MAPK activity GO:0000188 28 18 0,000 0,02858151 0,04667855 ! negative regulation of epithelial cell proliferation GO:0050680 36 18 0,000 0,02858151 0,04664645 ! vacuolar transport GO:0007034 26 18 0,000 0,02858151 0,04661439 ! pigmentation during development GO:0048066 35 18 0,000 0,02858151 0,04658237 ! cell-substrate junction assembly GO:0007044 45 18 0,000 0,02858151 0,0465504 ! cellular macromolecular complex disassembly GO:0034623 30 18 0,000 0,02858151 0,04651847 ! fucose metabolic process GO:0006004 27 18 0,000 0,02858151 0,04648659 ! actin filament bundle formation GO:0051017 30 18 0,000 0,02858151 0,04645475 ! body fluid secretion GO:0007589 27 18 0,000 0,02858151 0,04642295 ! regulation of dephosphorylation GO:0035303 38 18 0,000 0,02858151 0,0463912 ! NLS-bearing substrate import into nucleus GO:0006607 40 18 0,000 0,02858151 0,04635949 ! behavioral interaction between organisms GO:0051705 26 18 0,000 0,02858151 0,04632782 ! negative regulation of immune response GO:0050777 33 18 0,000 0,02858151 0,0462962 ! heart process GO:0003015 32 18 0,000 0,02858151 0,04626462 GO:0060047|heart contraction, ! regulation of T cell mediated immunity GO:0002709 39 18 0,000 0,02858151 0,04623308 ! sensory perception of pain GO:0019233 26 18 0,000 0,02858151 0,04620159 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 18 0,000 0,02858151 0,04617014 ! ribosomal small subunit biogenesis GO:0042274 22 18 0,000 0,02858151 0,04613873 ! somitogenesis GO:0001756 25 18 0,000 0,02858151 0,04610736 ! neural crest cell migration GO:0001755 28 18 0,000 0,02858151 0,04607604 ! neutrophil chemotaxis GO:0030593 26 18 0,000 0,02858151 0,04604476 ! positive regulation of intracellular transport GO:0032388 30 18 0,000 0,02858151 0,04601352 ! negative regulation of intracellular transport GO:0032387 31 18 0,000 0,02858151 0,04598233 ! synaptogenesis GO:0007416 28 18 0,000 0,02858151 0,04595117 ! cell-cell junction organization GO:0045216 28 18 0,000 0,02858151 0,04592006 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02858151 0,04588899 ! purine nucleotide catabolic process GO:0006195 27 18 0,000 0,02858151 0,04585797 ! proximal/distal pattern formation GO:0009954 28 18 0,000 0,02858151 0,04582698 ! regulation of generation of precursor metabolites and energy GO:0043467 29 18 0,000 0,02858151 0,04579604 ! aromatic compound catabolic process GO:0019439 26 18 0,000 0,02858151 0,04576514 ! somatic recombination of immunoglobulin gene segments GO:0016447 28 18 0,000 0,02858151 0,04573428 ! gut development GO:0048565 29 18 0,000 0,02858151 0,04570346 ! negative regulation of leukocyte proliferation GO:0070664 35 18 0,000 0,02858151 0,04567268 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! antigen receptor-mediated signaling pathway GO:0050851 33 18 0,000 0,02858151 0,04564195 ! positive regulation of synaptic transmission GO:0050806 26 18 0,000 0,02858151 0,04561125 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 28 19 0,000 0,03014595 0,0480755 ! positive regulation of translation GO:0045727 29 19 0,000 0,03014595 0,04804321 ! phosphatidylinositol metabolic process GO:0046488 24 19 0,000 0,03014595 0,04801097 ! glycerol metabolic process GO:0006071 22 19 0,000 0,03014595 0,04797877 ! phosphoinositide phosphorylation GO:0046854 26 19 0,000 0,03014595 0,04794661 ! regulation of neuronal synaptic plasticity GO:0048168 37 19 0,000 0,03014595 0,0479145 ! endothelial cell migration GO:0043542 24 19 0,000 0,03014595 0,04788243 ! glycosaminoglycan biosynthetic process GO:0006024 27 19 0,000 0,03014595 0,0478504 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 23 19 0,000 0,03014595 0,04781841 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 19 0,000 0,03014595 0,04778647 ! memory GO:0007613 28 19 0,000 0,03014595 0,04775457 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 19 0,000 0,03014595 0,04772271 ! pancreas development GO:0031016 27 19 0,000 0,03014595 0,0476909 ! response to carbohydrate stimulus GO:0009743 28 19 0,000 0,03014595 0,04765912 ! DNA duplex unwinding GO:0032508 28 19 0,000 0,03014595 0,04762739 GO:0032392|DNA geometric change, ! peroxisome organization GO:0007031 30 19 0,000 0,03014595 0,04759571 ! central nervous system neuron development GO:0021954 33 19 0,000 0,03014595 0,04756406 ! polysaccharide catabolic process GO:0000272 24 19 0,000 0,03014595 0,04753246 ! actin polymerization or depolymerization GO:0008154 32 19 0,000 0,03014595 0,04750089 ! vesicle docking during exocytosis GO:0006904 25 19 0,000 0,03014595 0,04746937 ! heme metabolic process GO:0042168 29 19 0,000 0,03014595 0,04743789 ! negative regulation of protein catabolic process GO:0042177 29 19 0,000 0,03014595 0,04740646 ! response to lipopolysaccharide GO:0032496 28 19 0,000 0,03014595 0,04737506 ! response to fungus GO:0009620 21 19 0,000 0,03014595 0,04734371 ! peptide cross-linking GO:0018149 35 19 0,000 0,03014595 0,0473124 ! ventricular cardiac muscle morphogenesis GO:0055010 25 19 0,000 0,03014595 0,04728113 ! determination of left/right symmetry GO:0007368 24 19 0,000 0,03014595 0,0472499 ! prostaglandin metabolic process GO:0006693 34 19 0,000 0,03014595 0,04721871 GO:0006692|prostanoid metabolic process, ! regulation of immunoglobulin mediated immune response GO:0002889 29 19 0,000 0,03014595 0,04718756 GO:0002712|regulation of B cell mediated immunity, ! detection of chemical stimulus GO:0009593 28 19 0,000 0,03014595 0,04715646 ! vitamin transport GO:0051180 26 19 0,000 0,03014595 0,04712539 ! sarcomere organization GO:0045214 26 19 0,000 0,03014595 0,04709437 ! positive regulation of myeloid cell differentiation GO:0045639 50 19 0,000 0,03014595 0,04706338 ! regulation of immunoglobulin production GO:0002637 29 19 0,000 0,03014595 0,04703244 ! positive regulation of transmission of nerve impulse GO:0051971 27 19 0,000 0,03014595 0,04700154 ! leukotriene biosynthetic process GO:0019370 27 19 0,000 0,03014595 0,04697068 GO:0043450|alkene biosynthetic process, ! regulation of glucose import GO:0046324 23 19 0,000 0,03014595 0,04693986 GO:0010827|regulation of glucose transport, ! negative regulation of coagulation GO:0050819 25 19 0,000 0,03014595 0,04690908 ! oligosaccharide metabolic process GO:0009311 35 20 0,000 0,03170795 0,04930732 ! positive regulation of angiogenesis GO:0045766 42 20 0,000 0,03170795 0,04927503 ! determination of bilateral symmetry GO:0009855 26 20 0,000 0,03170795 0,04924278 GO:0009799|determination of symmetry, ! N-acetylglucosamine metabolic process GO:0006044 25 20 0,000 0,03170795 0,04921057 ! lipid phosphorylation GO:0046834 28 20 0,000 0,03170795 0,04917841 ! aminoglycan biosynthetic process GO:0006023 28 20 0,000 0,03170795 0,04914629 ! hindlimb morphogenesis GO:0035137 35 20 0,000 0,03170795 0,04911421 ! C21-steroid hormone metabolic process GO:0008207 25 20 0,000 0,03170795 0,04908217 ! calcium-independent cell-cell adhesion GO:0016338 23 20 0,000 0,03170795 0,04905017 ! response to alkaloid GO:0043279 34 20 0,000 0,03170795 0,04901822 ! sensory perception of taste GO:0050909 26 20 0,000 0,03170795 0,04898631 ! response to retinoic acid GO:0032526 27 20 0,000 0,03170795 0,04895443 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 20 0,000 0,03170795 0,0489226 ! cellular response to reactive oxygen species GO:0034614 32 20 0,000 0,03170795 0,04889082 ! D-ribose metabolic process GO:0006014 27 20 0,000 0,03170795 0,04885907 ! cell structure disassembly during apoptosis GO:0006921 25 20 0,000 0,03170795 0,04882736 ! peptidyl-serine phosphorylation GO:0018105 31 20 0,000 0,03170795 0,0487957 ! sex determination GO:0007530 32 20 0,000 0,03170795 0,04876407 ! plasma membrane fusion GO:0045026 24 20 0,000 0,03170795 0,04873249 ! fatty acid beta-oxidation GO:0006635 32 20 0,000 0,03170795 0,04870095 ! positive regulation of alpha-beta T cell differentiation GO:0046638 29 20 0,000 0,03170795 0,04866945 ! cytolysis GO:0019835 21 20 0,000 0,03170795 0,04863799 ! renal system process GO:0003014 35 20 0,000 0,03170795 0,04860657 ! vasodilation GO:0042311 36 20 0,000 0,03170795 0,04857519 ! negative regulation of angiogenesis GO:0016525 38 20 0,000 0,03170795 0,04854385 ! detection of biotic stimulus GO:0009595 23 20 0,000 0,03170795 0,04851255 ! cellular response to nutrient levels GO:0031669 32 20 0,000 0,03170795 0,04848129 ! positive regulation of neurological system process GO:0031646 31 20 0,000 0,03170795 0,04845007 ! hormone transport GO:0009914 30 20 0,000 0,03170795 0,0484189 ! negative regulation of neuron differentiation GO:0045665 33 20 0,000 0,03170795 0,04838776 ! activation of JUN kinase activity GO:0007257 28 20 0,000 0,03170795 0,04835666 ! regulation of leukocyte mediated cytotoxicity GO:0001910 34 20 0,000 0,03170795 0,0483256 ! estrogen receptor signaling pathway GO:0030520 36 20 0,000 0,03170795 0,04829459 ! sperm-egg recognition GO:0035036 24 20 0,000 0,03170795 0,04826361 GO:0007339|binding of sperm to zona pellucida, ! embryonic organ morphogenesis GO:0048562 26 20 0,000 0,03170795 0,04823267 ! negative regulation of translation GO:0017148 28 20 0,000 0,03170795 0,04820177 ! cellular monovalent inorganic cation homeostasis GO:0030004 31 20 0,000 0,03170795 0,04817091 ! positive regulation of DNA replication GO:0045740 37 21 0,000 0,03326751 0,05050787 ! positive regulation of protein catabolic process GO:0045732 25 21 0,000 0,03326751 0,05047558 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,03326751 0,05044332 ! positive regulation of ossification GO:0045778 34 21 0,000 0,03326751 0,05041111 ! iron ion transport GO:0006826 49 21 0,000 0,03326751 0,05037894 ! glucosamine metabolic process GO:0006041 26 21 0,000 0,03326751 0,05034681 ! microtubule-based transport GO:0010970 41 21 0,000 0,03326751 0,05031472 ! vesicle docking GO:0048278 28 21 0,000 0,03326751 0,05028268 ! regulation of carbohydrate metabolic process GO:0006109 31 21 0,000 0,03326751 0,05025067 GO:0010675|regulation of cellular carbohydrate metabolic process, ! ovarian follicle development GO:0001541 33 21 0,000 0,03326751 0,0502187 ! response to ethanol GO:0045471 38 21 0,000 0,03326751 0,05018678 ! positive regulation of epithelial cell proliferation GO:0050679 43 21 0,000 0,03326751 0,05015489 ! smooth muscle contraction GO:0006939 39 21 0,000 0,03326751 0,05012305 ! glutamine metabolic process GO:0006541 29 21 0,000 0,03326751 0,05009124 ! response to vitamin A GO:0033189 28 21 0,000 0,03326751 0,05005948 ! purine ribonucleoside metabolic process GO:0046128 30 21 0,000 0,03326751 0,05002776 GO:0042278|purine nucleoside metabolic process, ! neurotransmitter metabolic process GO:0042133 36 21 0,000 0,03326751 0,04999607 ! response to starvation GO:0042594 35 21 0,000 0,03326751 0,04996443 ! regulation of myeloid leukocyte differentiation GO:0002761 41 21 0,000 0,03326751 0,04993283 ! leukotriene metabolic process GO:0006691 29 21 0,000 0,03326751 0,04990127 ! regulation of vasoconstriction GO:0019229 33 21 0,000 0,03326751 0,04986974 ! glycosphingolipid metabolic process GO:0006687 35 21 0,000 0,03326751 0,04983826 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 28 21 0,000 0,03326751 0,04980682 ! regulation of fatty acid metabolic process GO:0019217 32 21 0,000 0,03326751 0,04977541 ! visual learning GO:0008542 38 21 0,000 0,03326751 0,04974405 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 38 21 0,000 0,03326751 0,04971272 ! positive regulation of inflammatory response GO:0050729 38 21 0,000 0,03326751 0,04968144 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,03326751 0,04965019 ! neuromuscular process controlling balance GO:0050885 54 21 0,000 0,03326751 0,04961898 ! negative regulation of myeloid cell differentiation GO:0045638 29 21 0,000 0,03326751 0,04958782 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,03326751 0,04955669 ! aromatic amino acid family metabolic process GO:0009072 30 21 0,000 0,03326751 0,0495256 ! somatic diversification of immunoglobulins GO:0016445 31 21 0,000 0,03326751 0,04949455 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,03326751 0,04946354 ! negative regulation of T cell activation GO:0050868 35 21 0,000 0,03326751 0,04943256 ! regulation of microtubule polymerization or depolymerization GO:0031110 51 21 0,000 0,03326751 0,04940163 ! embryonic pattern specification GO:0009880 34 22 0,000 0,03482464 0,05168159 ! regulation of cell killing GO:0031341 37 22 0,000 0,03482464 0,05164929 ! regulation of anti-apoptosis GO:0045767 40 22 0,000 0,03482464 0,05161703 ! gluconeogenesis GO:0006094 26 22 0,000 0,03482464 0,05158481 ! DNA catabolic process, endonucleolytic GO:0000737 27 22 0,000 0,03482464 0,05155263 ! viral genome replication GO:0019079 31 22 0,000 0,03482464 0,05152049 ! nucleotide-excision repair, DNA damage removal GO:0000718 27 22 0,000 0,03482464 0,05148839 ! protein amino acid O-linked glycosylation GO:0006493 36 22 0,000 0,03482464 0,05145633 ! protein amino acid acylation GO:0043543 42 22 0,000 0,03482464 0,05142431 ! response to vitamin GO:0033273 31 22 0,000 0,03482464 0,05139233 ! molting cycle process GO:0022404 43 22 0,000 0,03482464 0,05136039 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of neurotransmitter transport GO:0051588 41 22 0,000 0,03482464 0,05132849 ! regeneration GO:0031099 37 22 0,000 0,03482464 0,05129663 ! phototransduction GO:0007602 29 22 0,000 0,03482464 0,0512648 ! regulation of DNA recombination GO:0000018 43 22 0,000 0,03482464 0,05123302 ! regulation of smooth muscle contraction GO:0006940 38 22 0,000 0,03482464 0,05120128 ! deoxyribonucleotide metabolic process GO:0009262 29 22 0,000 0,03482464 0,05116958 ! central nervous system neuron differentiation GO:0021953 39 22 0,000 0,03482464 0,05113791 ! cholesterol biosynthetic process GO:0006695 32 22 0,000 0,03482464 0,05110629 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 22 0,000 0,03482464 0,0510747 ! regulation of interleukin-6 production GO:0032675 25 22 0,000 0,03482464 0,05104315 ! regulation of interleukin-2 production GO:0032663 38 22 0,000 0,03482464 0,05101164 ! pallium development GO:0021543 43 22 0,000 0,03482464 0,05098018 ! positive regulation of locomotion GO:0040017 40 22 0,000 0,03482464 0,05094874 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! fatty acid transport GO:0015908 33 22 0,000 0,03482464 0,05091735 ! platelet activation GO:0030168 33 22 0,000 0,03482464 0,050886 ! proteoglycan biosynthetic process GO:0030166 33 22 0,000 0,03482464 0,05085469 ! regulation of cytokine secretion GO:0050707 30 22 0,000 0,03482464 0,05082341 ! positive regulation of osteoblast differentiation GO:0045669 37 22 0,000 0,03482464 0,05079217 ! cellular alkene metabolic process GO:0043449 30 22 0,000 0,03482464 0,05076097 ! cell-cell recognition GO:0009988 28 22 0,000 0,03482464 0,05072981 ! pyrimidine nucleoside metabolic process GO:0006213 28 22 0,000 0,03482464 0,05069869 ! water-soluble vitamin biosynthetic process GO:0042364 28 22 0,000 0,03482464 0,05066761 ! neural tube closure GO:0001843 35 22 0,000 0,03482464 0,05063656 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 26 22 0,000 0,03482464 0,05060555 ! regulation of multi-organism process GO:0043900 35 22 0,000 0,03482464 0,05057458 ! protein tetramerization GO:0051262 43 22 0,000 0,03482464 0,05054365 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 36 23 0,000 0,03637933 0,05276782 GO:0016444|somatic cell DNA recombination, ! reciprocal meiotic recombination GO:0007131 41 23 0,000 0,03637933 0,05273559 ! cellular aldehyde metabolic process GO:0006081 32 23 0,000 0,03637933 0,05270339 ! positive regulation of bone remodeling GO:0046852 37 23 0,000 0,03637933 0,05267124 ! cellular polysaccharide biosynthetic process GO:0033692 29 23 0,000 0,03637933 0,05263912 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 31 23 0,000 0,03637933 0,05260704 ! dicarboxylic acid metabolic process GO:0043648 36 23 0,000 0,03637933 0,05257501 ! regulation of chemotaxis GO:0050920 41 23 0,000 0,03637933 0,05254301 ! regulation of receptor-mediated endocytosis GO:0048259 26 23 0,000 0,03637933 0,05251105 ! tube lumen formation GO:0035148 37 23 0,000 0,03637933 0,05247912 ! macromolecular complex disassembly GO:0032984 39 23 0,000 0,03637933 0,05244724 ! dendrite development GO:0016358 41 23 0,000 0,03637933 0,0524154 ! vasculogenesis GO:0001570 38 23 0,000 0,03637933 0,05238359 ! microtubule organizing center organization GO:0031023 30 23 0,000 0,03637933 0,05235183 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 50 23 0,000 0,03637933 0,0523201 ! lysosome organization GO:0007040 41 23 0,000 0,03637933 0,05228841 ! digestive system process GO:0022600 35 23 0,000 0,03637933 0,05225676 ! positive regulation of cytoskeleton organization GO:0051495 43 23 0,000 0,03637933 0,05222514 ! vesicle targeting GO:0006903 35 23 0,000 0,03637933 0,05219357 ! response to corticosteroid stimulus GO:0031960 37 23 0,000 0,03637933 0,05216203 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 36 23 0,000 0,03637933 0,05213053 ! regulation of endothelial cell migration GO:0010594 44 23 0,000 0,03637933 0,05209907 ! regulation of insulin secretion GO:0050796 30 23 0,000 0,03637933 0,05206765 ! regulation of alpha-beta T cell differentiation GO:0046637 35 23 0,000 0,03637933 0,05203626 ! cardiac muscle tissue morphogenesis GO:0055008 29 23 0,000 0,03637933 0,05200492 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 42 23 0,000 0,03637933 0,05197361 ! membrane depolarization GO:0051899 40 23 0,000 0,03637933 0,05194233 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,03637933 0,0519111 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 39 23 0,000 0,03637933 0,0518799 ! regulation of ARF GTPase activity GO:0032312 35 23 0,000 0,03637933 0,05184874 ! DNA modification GO:0006304 33 23 0,000 0,03637933 0,05181762 ! collagen fibril organization GO:0030199 50 23 0,000 0,03637933 0,05178654 ! synaptic vesicle transport GO:0048489 45 23 0,000 0,03637933 0,05175549 ! peptidyl-serine modification GO:0018209 37 23 0,000 0,03637933 0,05172448 ! nerve-nerve synaptic transmission GO:0007270 42 23 0,000 0,03637933 0,05169351 ! fat-soluble vitamin metabolic process GO:0006775 29 23 0,000 0,03637933 0,05166257 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,03637933 0,05163167 ! collagen catabolic process GO:0030574 29 23 0,000 0,03637933 0,05160081 ! glutamine family amino acid catabolic process GO:0009065 34 23 0,000 0,03637933 0,05156999 ! aspartate family amino acid metabolic process GO:0009066 27 23 0,000 0,03637933 0,0515392 ! porphyrin metabolic process GO:0006778 37 23 0,000 0,03637933 0,05150845 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 39 23 0,000 0,03637933 0,05147773 ! blastocyst development GO:0001824 41 23 0,000 0,03637933 0,05144706 ! actin filament-based movement GO:0030048 37 23 0,000 0,03637933 0,05141641 ! protein stabilization GO:0050821 34 23 0,000 0,03637933 0,05138581 ! protein import into nucleus, docking GO:0000059 45 24 0,000 0,03793161 0,05354652 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 30 24 0,000 0,03793161 0,05351468 ! myelination GO:0042552 39 24 0,000 0,03793161 0,05348289 ! initiation of viral infection GO:0019059 47 24 0,000 0,03793161 0,05345113 ! regulation of transmembrane transport GO:0034762 31 24 0,000 0,03793161 0,05341941 ! leukocyte adhesion GO:0007159 49 24 0,000 0,03793161 0,05338772 ! glutamate signaling pathway GO:0007215 37 24 0,000 0,03793161 0,05335608 ! regulation of transcription factor import into nucleus GO:0042990 49 24 0,000 0,03793161 0,05332447 ! visual behavior GO:0007632 42 24 0,000 0,03793161 0,05329289 ! spinal cord development GO:0021510 41 24 0,000 0,03793161 0,05326136 ! immune response-activating cell surface receptor signaling pathway GO:0002429 39 24 0,000 0,03793161 0,05322986 ! multicellular organismal response to stress GO:0033555 42 24 0,000 0,03793161 0,0531984 ! regulation of nitric oxide biosynthetic process GO:0045428 42 24 0,000 0,03793161 0,05316698 ! negative regulation of DNA replication GO:0008156 39 24 0,000 0,03793161 0,0531356 ! cell aging GO:0007569 38 24 0,000 0,03793161 0,05310425 ! osteoblast differentiation GO:0001649 43 24 0,000 0,03793161 0,05307294 ! response to toxin GO:0009636 38 24 0,000 0,03793161 0,05304166 ! primary neural tube formation GO:0014020 37 24 0,000 0,03793161 0,05301042 ! vitamin biosynthetic process GO:0009110 30 24 0,000 0,03793161 0,05297922 ! positive regulation of alpha-beta T cell activation GO:0046635 40 24 0,000 0,03793161 0,05294806 ! cellular response to oxidative stress GO:0034599 38 24 0,000 0,03793161 0,05291693 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 24 0,000 0,03793161 0,05288584 ! fibroblast growth factor receptor signaling pathway GO:0008543 45 24 0,000 0,03793161 0,05285479 ! pentose metabolic process GO:0019321 33 24 0,000 0,03793161 0,05282377 ! immunoglobulin production GO:0002377 37 24 0,000 0,03793161 0,05279279 GO:0002440|production of molecular mediator of immune response, ! regulation of response to biotic stimulus GO:0002831 45 24 0,000 0,03793161 0,05276184 ! positive regulation of protein secretion GO:0050714 29 24 0,000 0,03793161 0,05273093 ! positive regulation of adaptive immune response GO:0002821 44 24 0,000 0,03793161 0,05270006 ! regulation of blood coagulation GO:0030193 37 24 0,000 0,03793161 0,05266922 ! positive regulation of tissue remodeling GO:0034105 41 24 0,000 0,03793161 0,05263842 ! group transfer coenzyme metabolic process GO:0006752 29 24 0,000 0,03793161 0,05260766 ! response to molecule of bacterial origin GO:0002237 38 24 0,000 0,03793161 0,05257693 ! positive regulation of JUN kinase activity GO:0043507 33 24 0,000 0,03793161 0,05254623 ! neuron fate commitment GO:0048663 38 25 0,000 0,03948145 0,05466131 ! pyruvate metabolic process GO:0006090 32 25 0,000 0,03948145 0,05462944 ! superoxide metabolic process GO:0006801 33 25 0,000 0,03948145 0,0545976 ! detection of light stimulus involved in sensory perception GO:0050962 32 25 0,000 0,03948145 0,05456581 GO:0050908|detection of light stimulus involved in visual perception, ! regulation of cell-matrix adhesion GO:0001952 57 25 0,000 0,03948145 0,05453405 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 44 25 0,000 0,03948145 0,05450232 ! mitochondrial membrane organization GO:0007006 42 25 0,000 0,03948145 0,05447063 ! vacuole organization GO:0007033 43 25 0,000 0,03948145 0,05443898 ! receptor metabolic process GO:0043112 40 25 0,000 0,03948145 0,05440737 ! barbed-end actin filament capping GO:0051016 41 25 0,000 0,03948145 0,05437579 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 35 25 0,000 0,03948145 0,05434425 ! regulation of behavior GO:0050795 45 25 0,000 0,03948145 0,05431275 ! hydrogen peroxide metabolic process GO:0042743 35 25 0,000 0,03948145 0,05428128 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 45 25 0,000 0,03948145 0,05424985 ! lymphocyte proliferation GO:0046651 42 25 0,000 0,03948145 0,05421845 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,03948145 0,0541871 ! regulation of tumor necrosis factor production GO:0032680 32 25 0,000 0,03948145 0,05415577 ! leukocyte homeostasis GO:0001776 40 25 0,000 0,03948145 0,05412449 ! positive regulation of nuclear division GO:0051785 41 25 0,000 0,03948145 0,05409324 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 38 25 0,000 0,03948145 0,05406203 ! camera-type eye morphogenesis GO:0048593 43 25 0,000 0,03948145 0,05403085 ! negative regulation of catabolic process GO:0009895 37 25 0,000 0,03948145 0,05399971 ! regulation of amine transport GO:0051952 44 25 0,000 0,03948145 0,0539686 ! liver development GO:0001889 44 25 0,000 0,03948145 0,05393753 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 38 26 0,000 0,04102888 0,0560193 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 31 26 0,000 0,04102888 0,05598708 ! positive regulation of cell projection organization GO:0031346 43 26 0,000 0,04102888 0,05595491 ! regulation of cellular catabolic process GO:0031329 39 26 0,000 0,04102888 0,05592277 ! regulation of interferon-gamma production GO:0032649 33 26 0,000 0,04102888 0,05589067 ! cellular iron ion homeostasis GO:0006879 47 26 0,000 0,04102888 0,0558586 ! epidermal growth factor receptor signaling pathway GO:0007173 42 26 0,000 0,04102888 0,05582657 ! amino sugar metabolic process GO:0006040 32 26 0,000 0,04102888 0,05579458 ! protein amino acid alkylation GO:0008213 40 26 0,000 0,04102888 0,05576262 GO:0006479|protein amino acid methylation, ! odontogenesis of dentine-containing tooth GO:0042475 43 26 0,000 0,04102888 0,0557307 ! insulin receptor signaling pathway GO:0008286 48 26 0,000 0,04102888 0,05569882 ! sperm motility GO:0030317 31 26 0,000 0,04102888 0,05566698 ! peptidyl-tyrosine phosphorylation GO:0018108 42 26 0,000 0,04102888 0,05563517 ! male gonad development GO:0008584 39 26 0,000 0,04102888 0,05560339 ! neural crest cell development GO:0014032 44 26 0,000 0,04102888 0,05557166 GO:0014033|neural crest cell differentiation, ! base-excision repair GO:0006284 35 26 0,000 0,04102888 0,05553995 ! cell fate determination GO:0001709 54 26 0,000 0,04102888 0,05550829 ! regulation of chromosome organization GO:0033044 37 26 0,000 0,04102888 0,05547666 ! regulation of oxidoreductase activity GO:0051341 42 26 0,000 0,04102888 0,05544507 ! detection of visible light GO:0009584 33 26 0,000 0,04102888 0,05541351 ! spermatid development GO:0007286 40 26 0,000 0,04102888 0,05538199 ! regulation of bone mineralization GO:0030500 38 26 0,000 0,04102888 0,05535051 ! regulation of osteoblast differentiation GO:0045667 41 26 0,000 0,04102888 0,05531906 ! acetyl-CoA catabolic process GO:0046356 38 26 0,000 0,04102888 0,05528764 GO:0006099|tricarboxylic acid cycle, ! regulation of JUN kinase activity GO:0043506 39 26 0,000 0,04102888 0,05525627 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,0425739 0,05730451 ! spliceosomal snRNP biogenesis GO:0000387 38 27 0,000 0,0425739 0,05727203 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 47 27 0,000 0,0425739 0,05723958 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 42 27 0,000 0,0425739 0,05720717 ! membrane docking GO:0022406 40 27 0,000 0,0425739 0,05717479 ! circadian rhythm GO:0007623 44 27 0,000 0,0425739 0,05714245 ! regulation of endothelial cell proliferation GO:0001936 52 27 0,000 0,0425739 0,05711015 ! positive regulation of innate immune response GO:0045089 34 27 0,000 0,0425739 0,05707789 ! autophagy GO:0006914 36 27 0,000 0,0425739 0,05704566 ! myofibril assembly GO:0030239 40 27 0,000 0,0425739 0,05701346 GO:0055002|striated muscle cell development, ! regulation of cellular ketone metabolic process GO:0010565 38 27 0,000 0,0425739 0,05698131 ! peptide transport GO:0015833 46 27 0,000 0,0425739 0,05694919 ! coenzyme catabolic process GO:0009109 40 27 0,000 0,0425739 0,0569171 ! regulation of peptide secretion GO:0002791 39 27 0,000 0,0425739 0,05688506 ! negative regulation of cell development GO:0010721 67 27 0,000 0,0425739 0,05685304 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 46 27 0,000 0,0425739 0,05682107 ! positive regulation of leukocyte mediated immunity GO:0002705 45 27 0,000 0,0425739 0,05678913 GO:0002708|positive regulation of lymphocyte mediated immunity, ! phospholipid transport GO:0015914 40 27 0,000 0,0425739 0,05675722 ! detection of light stimulus GO:0009583 35 27 0,000 0,0425739 0,05672536 ! glutathione metabolic process GO:0006749 35 27 0,000 0,0425739 0,05669352 ! lipid oxidation GO:0034440 39 27 0,000 0,0425739 0,05666173 GO:0019395|fatty acid oxidation, ! leukocyte proliferation GO:0070661 45 27 0,000 0,0425739 0,05662997 GO:0032943|mononuclear cell proliferation, ! telomere organization GO:0032200 39 27 0,000 0,0425739 0,05659824 GO:0000723|telomere maintenance, ! negative regulation of neuron apoptosis GO:0043524 48 27 0,000 0,0425739 0,05656655 ! protein import into nucleus, translocation GO:0000060 47 28 0,000 0,0441165 0,05858336 ! translational initiation GO:0006413 48 28 0,000 0,0441165 0,05855059 ! negative regulation of actin filament depolymerization GO:0030835 44 28 0,000 0,0441165 0,05851786 ! acetyl-CoA metabolic process GO:0006084 42 28 0,000 0,0441165 0,05848517 ! regulation of pH GO:0006885 40 28 0,000 0,0441165 0,05845252 ! negative regulation of protein modification process GO:0031400 56 28 0,000 0,0441165 0,0584199 ! catechol metabolic process GO:0009712 46 28 0,000 0,0441165 0,05838731 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 43 28 0,000 0,0441165 0,05835477 ! cellular carbohydrate biosynthetic process GO:0034637 37 28 0,000 0,0441165 0,05832226 ! iron ion homeostasis GO:0055072 49 28 0,000 0,0441165 0,05828979 ! regulation of biomineral formation GO:0070167 40 28 0,000 0,0441165 0,05825735 ! peptidyl-tyrosine modification GO:0018212 44 28 0,000 0,0441165 0,05822495 ! neurotransmitter secretion GO:0007269 41 28 0,000 0,0441165 0,05819258 ! negative regulation of transcription regulator activity GO:0090048 48 28 0,000 0,0441165 0,05816025 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of lymphocyte activation GO:0051250 48 28 0,000 0,0441165 0,05812796 ! gene silencing GO:0016458 47 28 0,000 0,0441165 0,0580957 ! regulation of coagulation GO:0050818 42 28 0,000 0,0441165 0,05806348 ! negative regulation of actin filament polymerization GO:0030837 45 29 0,000 0,0456567 0,06005728 ! phenol metabolic process GO:0018958 47 29 0,000 0,0456567 0,06002401 ! positive regulation of cell adhesion GO:0045785 54 29 0,000 0,0456567 0,05999077 ! icosanoid biosynthetic process GO:0046456 45 29 0,000 0,0456567 0,05995758 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 39 29 0,000 0,0456567 0,05992441 ! calcium-dependent cell-cell adhesion GO:0016339 36 29 0,000 0,0456567 0,05989129 ! negative regulation of response to external stimulus GO:0032102 39 29 0,000 0,0456567 0,0598582 ! cholesterol transport GO:0030301 48 29 0,000 0,0456567 0,05982515 GO:0015918|sterol transport, ! cholesterol homeostasis GO:0042632 53 29 0,000 0,0456567 0,05979213 GO:0055092|sterol homeostasis, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 39 29 0,000 0,0456567 0,05975915 ! GPI anchor metabolic process GO:0006505 47 29 0,000 0,0456567 0,05972621 ! complement activation, classical pathway GO:0006958 39 29 0,000 0,0456567 0,0596933 ! multicellular organismal catabolic process GO:0044243 36 29 0,000 0,0456567 0,05966043 ! respiratory gaseous exchange GO:0007585 51 29 0,000 0,0456567 0,05962759 ! triglyceride metabolic process GO:0006641 38 29 0,000 0,0456567 0,0595948 ! response to ionizing radiation GO:0010212 55 29 0,000 0,0456567 0,05956203 ! muscle cell development GO:0055001 42 29 0,000 0,0456567 0,05952931 ! response to organic cyclic substance GO:0014070 53 29 0,000 0,0456567 0,05949662 ! regulation of systemic arterial blood pressure GO:0003073 52 29 0,000 0,0456567 0,05946396 ! mesoderm formation GO:0001707 52 29 0,000 0,0456567 0,05943134 ! response to estradiol stimulus GO:0032355 38 29 0,000 0,0456567 0,05939876 ! positive regulation of MAPKKK cascade GO:0043410 45 29 0,000 0,0456567 0,05936621 ! regulation of microtubule cytoskeleton organization GO:0070507 61 29 0,000 0,0456567 0,0593337 ! ensheathment of neurons GO:0007272 48 29 0,000 0,0456567 0,05930123 GO:0008366|axon ensheathment, ! spermatid differentiation GO:0048515 45 29 0,000 0,0456567 0,05926878 ! myeloid leukocyte activation GO:0002274 44 29 0,000 0,0456567 0,05923638 ! neural tube formation GO:0001841 46 29 0,000 0,0456567 0,05920401 ! regulation of actin filament depolymerization GO:0030834 47 30 0,000 0,04719449 0,06116467 ! organic anion transport GO:0015711 50 30 0,000 0,04719449 0,06113129 ! cell junction assembly GO:0034329 65 30 0,000 0,04719449 0,06109794 ! acute-phase response GO:0006953 49 30 0,000 0,04719449 0,06106462 ! segmentation GO:0035282 43 30 0,000 0,04719449 0,06103134 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 56 30 0,000 0,04719449 0,0609981 ! negative regulation of protein kinase cascade GO:0010741 58 30 0,000 0,04719449 0,0609649 ! immune response-activating signal transduction GO:0002757 45 30 0,000 0,04719449 0,06093173 ! regulation of protein import into nucleus GO:0042306 56 30 0,000 0,04719449 0,06089859 ! regulation of production of molecular mediator of immune response GO:0002700 47 30 0,000 0,04719449 0,0608655 ! ceramide metabolic process GO:0006672 47 30 0,000 0,04719449 0,06083244 ! formation of primary germ layer GO:0001704 54 30 0,000 0,04719449 0,06079941 ! nicotinamide metabolic process GO:0006769 47 30 0,000 0,04719449 0,06076642 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 50 30 0,000 0,04719449 0,06073347 ! fatty acid catabolic process GO:0009062 45 30 0,000 0,04719449 0,06070055 ! regulation of calcium ion transport GO:0051924 40 30 0,000 0,04719449 0,06066767 ! negative regulation of protein polymerization GO:0032272 47 30 0,000 0,04719449 0,06063482 ! negative regulation of protein transport GO:0051224 53 30 0,000 0,04719449 0,06060201 ! response to heat GO:0009408 43 30 0,000 0,04719449 0,06056923 ! establishment of vesicle localization GO:0051650 48 30 0,000 0,04719449 0,06053649 ! alkaloid metabolic process GO:0009820 48 31 0,000 0,04872988 0,06247218 ! response to hydrogen peroxide GO:0042542 48 31 0,000 0,04872988 0,06243844 ! post-embryonic development GO:0009791 50 31 0,000 0,04872988 0,06240475 ! inner ear morphogenesis GO:0042472 43 31 0,000 0,04872988 0,06237109 ! regulation of innate immune response GO:0045088 42 31 0,000 0,04872988 0,06233746 ! ovulation cycle process GO:0022602 46 31 0,000 0,04872988 0,06230388 ! mesoderm morphogenesis GO:0048332 54 31 0,000 0,04872988 0,06227033 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 42 31 0,000 0,04872988 0,06223681 ! immune response-regulating signal transduction GO:0002764 51 31 0,000 0,04872988 0,06220333 ! positive regulation of neurogenesis GO:0050769 49 31 0,000 0,04872988 0,06216989 ! positive regulation of T cell differentiation GO:0045582 45 31 0,000 0,04872988 0,06213648 ! positive regulation of multicellular organism growth GO:0040018 42 31 0,000 0,04872988 0,06210311 ! hexose biosynthetic process GO:0019319 37 31 0,000 0,04872988 0,06206978 ! negative regulation of MAP kinase activity GO:0043407 57 31 0,000 0,04872988 0,06203648 ! sterol biosynthetic process GO:0016126 48 31 0,000 0,04872988 0,06200322 ! biogenic amine biosynthetic process GO:0042401 45 31 0,000 0,04872988 0,06196999 ! embryonic epithelial tube formation GO:0001838 50 31 0,000 0,04872988 0,06193679 ! tissue homeostasis GO:0001894 45 31 0,000 0,04872988 0,06190364 GO:0048871|multicellular organismal homeostasis, ! mitotic sister chromatid segregation GO:0000070 47 32 0,000 0,05026287 0,0638169 ! DNA damage checkpoint GO:0000077 57 32 0,000 0,05026287 0,06378277 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 49 32 0,000 0,05026287 0,06374868 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 45 32 0,000 0,05026287 0,06371463 ! negative regulation of protein complex assembly GO:0031333 51 32 0,000 0,05026287 0,06368061 ! regulation of synaptic plasticity GO:0048167 54 32 0,000 0,05026287 0,06364663 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 32 0,000 0,05026287 0,06361269 ! positive regulation of endocytosis GO:0045807 39 32 0,000 0,05026287 0,06357878 ! positive regulation of T cell proliferation GO:0042102 56 32 0,000 0,05026287 0,06354491 ! regulation of striated muscle tissue development GO:0016202 51 32 0,000 0,05026287 0,06351107 ! unsaturated fatty acid biosynthetic process GO:0006636 50 32 0,000 0,05026287 0,06347727 ! regulation of axonogenesis GO:0050770 60 32 0,000 0,05026287 0,0634435 ! telencephalon development GO:0021537 59 32 0,000 0,05026287 0,06340978 ! ovulation cycle GO:0042698 48 32 0,000 0,05026287 0,06337608 ! cofactor catabolic process GO:0051187 52 32 0,000 0,05026287 0,06334243 ! pyridine nucleotide metabolic process GO:0019362 49 32 0,000 0,05026287 0,06330881 ! positive regulation of catabolic process GO:0009896 44 32 0,000 0,05026287 0,06327522 ! placenta development GO:0001890 45 32 0,000 0,05026287 0,06324167 ! symbiosis, encompassing mutualism through parasitism GO:0044403 52 32 0,000 0,05026287 0,06320816 ! vesicle localization GO:0051648 50 32 0,000 0,05026287 0,06317468 ! regulation of muscle development GO:0048634 52 33 0,000 0,05179347 0,065064 ! mRNA export from nucleus GO:0006406 47 33 0,000 0,05179347 0,06502958 ! negative regulation of secretion GO:0051048 53 33 0,000 0,05179347 0,06499519 ! negative regulation of DNA metabolic process GO:0051053 53 33 0,000 0,05179347 0,06496084 ! glial cell differentiation GO:0010001 65 33 0,000 0,05179347 0,06492652 ! cellular component assembly involved in morphogenesis GO:0010927 52 33 0,000 0,05179347 0,06489224 ! sister chromatid segregation GO:0000819 48 33 0,000 0,05179347 0,064858 ! sphingoid metabolic process GO:0046519 51 33 0,000 0,05179347 0,06482379 ! maintenance of protein location in cell GO:0032507 66 33 0,000 0,05179347 0,06478962 ! pigment biosynthetic process GO:0046148 55 33 0,000 0,05179347 0,06475548 ! neutral lipid metabolic process GO:0006638 45 33 0,000 0,05179347 0,06472138 GO:0006639|acylglycerol metabolic process, ! erythrocyte differentiation GO:0030218 50 33 0,000 0,05179347 0,06468732 ! protein targeting to membrane GO:0006612 63 33 0,000 0,05179347 0,06465329 ! nucleotide catabolic process GO:0009166 47 33 0,000 0,05179347 0,0646193 ! nuclear-transcribed mRNA catabolic process GO:0000956 47 33 0,000 0,05179347 0,06458534 ! leukocyte chemotaxis GO:0030595 48 33 0,000 0,05179347 0,06455142 GO:0060326|cell chemotaxis, ! BMP signaling pathway GO:0030509 49 33 0,000 0,05179347 0,06451753 ! calcium-mediated signaling GO:0019722 54 33 0,000 0,05179347 0,06448368 ! cytokine production GO:0001816 49 33 0,000 0,05179347 0,06444987 ! regulation of microtubule-based process GO:0032886 66 33 0,000 0,05179347 0,06441609 ! RNA modification GO:0009451 43 33 0,000 0,05179347 0,06438235 ! positive regulation of immune effector process GO:0002699 53 33 0,000 0,05179347 0,06434864 ! negative regulation of adenylate cyclase activity GO:0007194 56 34 0,000 0,05332168 0,06621263 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! ER to Golgi vesicle-mediated transport GO:0006888 57 34 0,000 0,05332168 0,066178 ! xenobiotic metabolic process GO:0006805 49 34 0,000 0,05332168 0,06614341 ! actomyosin structure organization GO:0031032 48 34 0,000 0,05332168 0,06610885 ! embryonic skeletal system morphogenesis GO:0048704 49 34 0,000 0,05332168 0,06607433 ! monovalent inorganic cation homeostasis GO:0055067 49 34 0,000 0,05332168 0,06603985 ! negative regulation of DNA binding GO:0043392 54 34 0,000 0,05332168 0,0660054 ! positive regulation of cell development GO:0010720 58 34 0,000 0,05332168 0,06597098 ! response to mechanical stimulus GO:0009612 46 34 0,000 0,05332168 0,0659366 ! cell fate specification GO:0001708 49 34 0,000 0,05332168 0,06590226 ! peripheral nervous system development GO:0007422 58 34 0,000 0,05332168 0,06586796 ! isoprenoid metabolic process GO:0006720 47 34 0,000 0,05332168 0,06583369 ! adult locomotory behavior GO:0008344 54 34 0,000 0,05332168 0,06579945 ! monosaccharide biosynthetic process GO:0046364 40 34 0,000 0,05332168 0,06576525 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 47 35 0,000 0,0548475 0,06761201 ! phosphoinositide biosynthetic process GO:0046489 54 35 0,000 0,0548475 0,06757691 ! collagen metabolic process GO:0032963 47 35 0,000 0,0548475 0,06754184 ! cell junction organization GO:0034330 72 35 0,000 0,0548475 0,06750681 ! regulation of ARF protein signal transduction GO:0032012 56 35 0,000 0,0548475 0,06747181 ! metanephros development GO:0001656 61 35 0,000 0,0548475 0,06743685 ! positive regulation of gene-specific transcription GO:0043193 53 35 0,000 0,0548475 0,06740193 ! female gonad development GO:0008585 55 35 0,000 0,0548475 0,06736704 ! lipid homeostasis GO:0055088 63 35 0,000 0,0548475 0,06733219 ! DNA integrity checkpoint GO:0031570 61 35 0,000 0,0548475 0,06729738 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,0548475 0,0672626 ! hindbrain development GO:0030902 56 35 0,000 0,0548475 0,06722785 ! Rho protein signal transduction GO:0007266 53 35 0,000 0,0548475 0,06719315 ! positive regulation of lymphocyte differentiation GO:0045621 51 35 0,000 0,0548475 0,06715847 ! hormone biosynthetic process GO:0042446 49 35 0,000 0,0548475 0,06712384 ! cytokinesis GO:0000910 57 35 0,000 0,0548475 0,06708924 ! embryonic organ development GO:0048568 53 35 0,000 0,0548475 0,06705467 ! pyrimidine nucleotide metabolic process GO:0006220 48 35 0,000 0,0548475 0,06702015 ! negative regulation of cell activation GO:0050866 58 35 0,000 0,0548475 0,06698565 ! protein homooligomerization GO:0051260 59 35 0,000 0,0548475 0,0669512 ! negative regulation of cell adhesion GO:0007162 78 36 0,000 0,05637094 0,06877545 ! regulation of metal ion transport GO:0010959 50 36 0,000 0,05637094 0,06874011 ! regulation of intracellular protein transport GO:0033157 64 36 0,000 0,05637094 0,0687048 ! development of primary male sexual characteristics GO:0046546 52 36 0,000 0,05637094 0,06866953 ! spliceosome assembly GO:0000245 65 36 0,000 0,05637094 0,0686343 ! mismatch repair GO:0006298 42 36 0,000 0,05637094 0,0685991 ! regulation of action potential in neuron GO:0019228 60 36 0,000 0,05637094 0,06856394 ! glycerol ether metabolic process GO:0006662 49 36 0,000 0,05637094 0,06852882 ! regulation of proteolysis GO:0030162 53 36 0,000 0,05637094 0,06849373 ! energy coupled proton transport, down electrochemical gradient GO:0015985 55 36 0,000 0,05637094 0,06845867 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 53 36 0,000 0,05637094 0,06842366 ! dorsal/ventral pattern formation GO:0009953 50 36 0,000 0,05637094 0,06838868 ! eye morphogenesis GO:0048592 64 36 0,000 0,05637094 0,06835373 ! cellular response to insulin stimulus GO:0032869 60 36 0,000 0,05637094 0,06831882 ! positive regulation of DNA metabolic process GO:0051054 64 37 0,000 0,05789201 0,07012646 ! mammary gland development GO:0030879 73 37 0,000 0,05789201 0,07009068 ! positive regulation of JAK-STAT cascade GO:0046427 49 37 0,000 0,05789201 0,07005494 ! ear morphogenesis GO:0042471 50 37 0,000 0,05789201 0,07001923 ! odontogenesis GO:0042476 60 37 0,000 0,05789201 0,06998356 ! negative regulation of binding GO:0051100 59 37 0,000 0,05789201 0,06994793 ! mitotic cell cycle checkpoint GO:0007093 74 37 0,000 0,05789201 0,06991233 ! tissue remodeling GO:0048771 65 37 0,000 0,05789201 0,06987677 ! carbohydrate homeostasis GO:0033500 45 37 0,000 0,05789201 0,06984125 GO:0042593|glucose homeostasis, ! natural killer cell activation GO:0030101 45 37 0,000 0,05789201 0,06980576 ! polyol metabolic process GO:0019751 47 37 0,000 0,05789201 0,06977031 ! androgen receptor signaling pathway GO:0030521 66 37 0,000 0,05789201 0,06973489 ! glucan metabolic process GO:0044042 54 37 0,000 0,05789201 0,06969951 GO:0006073|cellular glucan metabolic process, ! positive regulation of transcription factor activity GO:0051091 57 38 0,000 0,05941069 0,07149167 GO:0090047|positive regulation of transcription regulator activity, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 48 38 0,000 0,05941069 0,07145544 GO:0006956|complement activation, ! regulation of hormone secretion GO:0046883 54 38 0,000 0,05941069 0,07141924 ! regulation of neuron projection development GO:0010975 73 38 0,000 0,05941069 0,07138308 ! feeding behavior GO:0007631 50 38 0,000 0,05941069 0,07134695 ! organic ether metabolic process GO:0018904 51 38 0,000 0,05941069 0,07131086 ! antigen processing and presentation of peptide antigen GO:0048002 67 38 0,000 0,05941069 0,07127481 ! development of primary female sexual characteristics GO:0046545 59 38 0,000 0,05941069 0,0712388 GO:0046660|female sex differentiation, ! regulation of Rab protein signal transduction GO:0032483 58 38 0,000 0,05941069 0,07120282 GO:0032313|regulation of Rab GTPase activity, ! multicellular organismal macromolecule metabolic process GO:0044259 51 38 0,000 0,05941069 0,07116687 ! ion transmembrane transport GO:0034220 58 38 0,000 0,05941069 0,07113097 ! heterocycle biosynthetic process GO:0018130 49 38 0,000 0,05941069 0,0710951 ! ribonucleoside metabolic process GO:0009119 51 38 0,000 0,05941069 0,07105926 ! neuron migration GO:0001764 59 38 0,000 0,05941069 0,07102346 ! maintenance of protein location GO:0045185 72 38 0,000 0,05941069 0,0709877 ! pigment metabolic process GO:0042440 66 38 0,000 0,05941069 0,07095198 ! regulation of cell morphogenesis involved in differentiation GO:0010769 72 38 0,000 0,05941069 0,07091629 ! mRNA catabolic process GO:0006402 58 39 0,000 0,06092701 0,07268969 ! response to reactive oxygen species GO:0000302 64 39 0,000 0,06092701 0,07265316 ! establishment or maintenance of cell polarity GO:0007163 74 39 0,000 0,06092701 0,07261667 ! striated muscle cell differentiation GO:0051146 58 39 0,000 0,06092701 0,07258022 ! neural tube development GO:0021915 58 39 0,000 0,06092701 0,0725438 ! polysaccharide biosynthetic process GO:0000271 51 39 0,000 0,06092701 0,07250742 ! regulation of protein stability GO:0031647 58 39 0,000 0,06092701 0,07247107 ! female gamete generation GO:0007292 50 39 0,000 0,06092701 0,07243477 ! aerobic respiration GO:0009060 56 39 0,000 0,06092701 0,07239849 ! response to xenobiotic stimulus GO:0009410 55 39 0,000 0,06092701 0,07236226 ! protein amino acid N-linked glycosylation GO:0006487 57 40 0,000 0,06244096 0,07412326 ! Notch signaling pathway GO:0007219 64 40 0,000 0,06244096 0,07408619 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 68 40 0,000 0,06244096 0,07404917 ! monocarboxylic acid transport GO:0015718 68 40 0,000 0,06244096 0,07401218 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 71 40 0,000 0,06244096 0,07397523 ! hormone-mediated signaling GO:0009755 57 40 0,000 0,06244096 0,07393832 ! alcohol biosynthetic process GO:0046165 48 40 0,000 0,06244096 0,07390144 ! phagocytosis GO:0006909 65 40 0,000 0,06244096 0,0738646 ! mesenchymal cell development GO:0014031 70 40 0,000 0,06244096 0,0738278 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! erythrocyte homeostasis GO:0034101 60 40 0,000 0,06244096 0,07379103 ! B cell differentiation GO:0030183 70 40 0,000 0,06244096 0,0737543 ! pigmentation GO:0043473 81 40 0,000 0,06244096 0,07371761 ! developmental growth GO:0048589 70 40 0,000 0,06244096 0,07368095 ! synapse organization GO:0050808 61 40 0,000 0,06244096 0,07364433 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 61 41 0,000 0,06395254 0,07538965 ! RNA export from nucleus GO:0006405 57 41 0,000 0,06395254 0,07535222 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 72 41 0,000 0,06395254 0,07531483 ! detection of stimulus involved in sensory perception GO:0050906 55 41 0,000 0,06395254 0,07527747 ! regulation of epithelial cell proliferation GO:0050678 80 41 0,000 0,06395254 0,07524015 ! ATP synthesis coupled electron transport GO:0042773 50 41 0,000 0,06395254 0,07520286 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of protein secretion GO:0050708 55 41 0,000 0,06395254 0,07516561 ! cell growth GO:0016049 71 41 0,000 0,06395254 0,0751284 ! maintenance of location in cell GO:0051651 77 41 0,000 0,06395254 0,07509123 ! transforming growth factor beta receptor signaling pathway GO:0007179 59 42 0,000 0,06546176 0,0768253 ! regulation of nucleocytoplasmic transport GO:0046822 75 42 0,000 0,06546176 0,07678732 ! learning GO:0007612 75 42 0,000 0,06546176 0,07674939 ! negative regulation of protein complex disassembly GO:0043242 78 42 0,000 0,06546176 0,07671148 ! cellular amide metabolic process GO:0043603 63 42 0,000 0,06546176 0,07667362 ! morphogenesis of embryonic epithelium GO:0016331 69 42 0,000 0,06546176 0,07663579 ! gliogenesis GO:0042063 85 42 0,000 0,06546176 0,07659801 ! endosome transport GO:0016197 74 42 0,000 0,06546176 0,07656025 ! male sex differentiation GO:0046661 62 42 0,000 0,06546176 0,07652254 ! double-strand break repair GO:0006302 75 42 0,000 0,06546176 0,07648486 ! regulation of myeloid cell differentiation GO:0045637 78 42 0,000 0,06546176 0,07644722 ! oxidoreduction coenzyme metabolic process GO:0006733 62 42 0,000 0,06546176 0,07640962 ! mitochondrial transport GO:0006839 66 43 0,000 0,06696862 0,07813006 ! protein amino acid lipidation GO:0006497 69 43 0,000 0,06696862 0,07809167 ! energy reserve metabolic process GO:0006112 67 43 0,000 0,06696862 0,07805331 ! regulation of tube size GO:0035150 69 43 0,000 0,06696862 0,07801499 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 78 43 0,000 0,06696862 0,07797671 ! regulation of T cell proliferation GO:0042129 72 43 0,000 0,06696862 0,07793847 ! positive regulation of DNA binding GO:0043388 65 43 0,000 0,06696862 0,07790027 ! T cell differentiation GO:0030217 78 43 0,000 0,06696862 0,0778621 ! icosanoid metabolic process GO:0006690 65 43 0,000 0,06696862 0,07782397 ! positive regulation of protein transport GO:0051222 59 43 0,000 0,06696862 0,07778588 ! epithelial cell differentiation GO:0030855 64 44 0,000 0,06847313 0,07949449 ! receptor-mediated endocytosis GO:0006898 85 44 0,000 0,06847313 0,07945562 ! cellular component disassembly GO:0022411 66 44 0,000 0,06847313 0,07941679 ! cytoskeleton-dependent intracellular transport GO:0030705 78 44 0,000 0,06847313 0,07937799 ! peptide metabolic process GO:0006518 64 44 0,000 0,06847313 0,07933923 ! multicellular organismal metabolic process GO:0044236 57 44 0,000 0,06847313 0,07930051 ! inner ear development GO:0048839 66 44 0,000 0,06847313 0,07926183 ! regulation of lymphocyte mediated immunity GO:0002706 77 44 0,000 0,06847313 0,07922318 ! regulation of gene expression, epigenetic GO:0040029 86 44 0,000 0,06847313 0,07918457 ! chromatin remodeling GO:0006338 73 44 0,000 0,06847313 0,079146 ! biopolymer methylation GO:0043414 67 44 0,000 0,06847313 0,07910747 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 58 44 0,000 0,06847313 0,07906898 ! JNK cascade GO:0007254 66 44 0,000 0,06847313 0,07903052 ! regulation of cell shape GO:0008360 83 44 0,000 0,06847313 0,0789921 ! activation of adenylate cyclase activity GO:0007190 79 45 0,000 0,06997529 0,0806858 ! positive regulation of binding GO:0051099 67 45 0,000 0,06997529 0,08064661 ! stress-activated protein kinase signaling pathway GO:0031098 69 45 0,000 0,06997529 0,08060746 ! regulation of ion transport GO:0043269 60 45 0,000 0,06997529 0,08056835 ! glucose transport GO:0015758 60 45 0,000 0,06997529 0,08052928 ! neuromuscular process GO:0050905 89 45 0,000 0,06997529 0,08049024 ! positive regulation of cytokine biosynthetic process GO:0042108 61 45 0,000 0,06997529 0,08045125 ! glycosaminoglycan metabolic process GO:0030203 68 45 0,000 0,06997529 0,08041229 ! regulation of T cell differentiation GO:0045580 68 45 0,000 0,06997529 0,08037337 ! response to insulin stimulus GO:0032868 71 45 0,000 0,06997529 0,08033448 ! regulation of actin filament polymerization GO:0030833 71 46 0,000 0,07147511 0,08201665 ! regulation of translational initiation GO:0006446 70 46 0,000 0,07147511 0,08197701 ! regulation of JAK-STAT cascade GO:0046425 68 46 0,000 0,07147511 0,08193741 ! regulation of action potential GO:0001508 80 46 0,000 0,07147511 0,08189784 ! hexose transport GO:0008645 62 46 0,000 0,07147511 0,08185831 GO:0015749|monosaccharide transport, ! activation of caspase activity GO:0006919 70 46 0,000 0,07147511 0,08181883 ! excretion GO:0007588 72 46 0,000 0,07147511 0,08177938 ! regulation of leukocyte mediated immunity GO:0002703 80 46 0,000 0,07147511 0,08173997 ! regulation of inflammatory response GO:0050727 74 46 0,000 0,07147511 0,08170059 ! epithelial tube morphogenesis GO:0060562 73 46 0,000 0,07147511 0,08166126 ! positive regulation of defense response GO:0031349 70 47 0,000 0,07297258 0,08333201 ! branching morphogenesis of a tube GO:0048754 85 47 0,000 0,07297258 0,08329193 ! embryonic skeletal system development GO:0048706 65 47 0,000 0,07297258 0,08325189 ! unsaturated fatty acid metabolic process GO:0033559 71 47 0,000 0,07297258 0,08321188 ! lipoprotein biosynthetic process GO:0042158 74 47 0,000 0,07297258 0,08317191 ! regulation of JNK cascade GO:0046328 72 47 0,000 0,07297258 0,08313198 ! positive regulation of adenylate cyclase activity GO:0045762 90 48 0,000 0,07446771 0,08479456 ! viral infectious cycle GO:0019058 80 48 0,000 0,07446771 0,08475389 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 75 48 0,000 0,07446771 0,08471326 ! leukocyte migration GO:0050900 76 48 0,000 0,07446771 0,08467267 ! cellular amino acid biosynthetic process GO:0008652 60 48 0,000 0,07446771 0,08463212 ! striated muscle contraction GO:0006941 78 48 0,000 0,07446771 0,08459161 ! vascular process in circulatory system GO:0003018 78 48 0,000 0,07446771 0,08455113 ! DNA-dependent DNA replication GO:0006261 73 48 0,000 0,07446771 0,0845107 ! tRNA processing GO:0008033 56 48 0,000 0,07446771 0,0844703 ! cell maturation GO:0048469 69 48 0,000 0,07446771 0,08442994 ! detection of abiotic stimulus GO:0009582 66 48 0,000 0,07446771 0,08438962 ! vesicle organization GO:0016050 87 48 0,000 0,07446771 0,08434934 ! regulation of neuron apoptosis GO:0043523 84 48 0,000 0,07446771 0,0843091 ! respiratory electron transport chain GO:0022904 63 49 0,000 0,0759605 0,08595816 ! regulation of cell projection organization GO:0031344 95 49 0,000 0,0759605 0,08591719 ! regulation of gene-specific transcription GO:0032583 78 49 0,000 0,0759605 0,08587626 ! regulation of protein complex disassembly GO:0043244 88 49 0,000 0,0759605 0,08583537 ! induction of apoptosis by extracellular signals GO:0008624 96 49 0,000 0,0759605 0,08579451 ! response to temperature stimulus GO:0009266 66 49 0,000 0,0759605 0,0857537 ! endocrine system development GO:0035270 86 49 0,000 0,0759605 0,08571292 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,0759605 0,08567218 ! generation of a signal involved in cell-cell signaling GO:0003001 74 49 0,000 0,0759605 0,08563148 ! gastrulation GO:0007369 80 49 0,000 0,0759605 0,08559082 ! RNA elongation from RNA polymerase II promoter GO:0006368 65 49 0,000 0,0759605 0,0855502 ! positive regulation of cyclase activity GO:0031281 91 49 0,000 0,0759605 0,08550962 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 84 49 0,000 0,0759605 0,08546907 ! regulation of intracellular transport GO:0032386 83 49 0,000 0,0759605 0,08542856 ! methylation GO:0032259 74 49 0,000 0,0759605 0,0853881 ! cell redox homeostasis GO:0045454 72 50 0,000 0,07745096 0,08702232 ! negative regulation of cell migration GO:0030336 105 50 0,000 0,07745096 0,08698113 ! regulation of muscle contraction GO:0006937 75 50 0,000 0,07745096 0,08693999 ! cellular polysaccharide metabolic process GO:0044264 70 50 0,000 0,07745096 0,08689888 ! histone modification GO:0016570 81 50 0,000 0,07745096 0,08685781 ! positive regulation of lyase activity GO:0051349 92 50 0,000 0,07745096 0,08681678 ! heterocycle catabolic process GO:0046700 74 50 0,000 0,07745096 0,08677579 ! RNA catabolic process GO:0006401 77 51 0,000 0,07893909 0,08840136 ! chloride transport GO:0006821 78 51 0,000 0,07893909 0,08835966 ! positive regulation of caspase activity GO:0043280 77 51 0,000 0,07893909 0,088318 GO:0010952|positive regulation of peptidase activity, ! membrane fusion GO:0006944 82 51 0,000 0,07893909 0,08827638 ! regulation of ossification GO:0030278 82 51 0,000 0,07893909 0,0882348 ! heart morphogenesis GO:0003007 71 51 0,000 0,07893909 0,08819325 ! RNA elongation GO:0006354 67 51 0,000 0,07893909 0,08815175 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 74 51 0,000 0,07893909 0,08811029 ! aminoglycan metabolic process GO:0006022 77 52 0,000 0,0804249 0,08972651 ! activation of phospholipase C activity GO:0007202 93 52 0,000 0,0804249 0,08968435 GO:0010863|positive regulation of phospholipase C activity, ! skeletal muscle fiber development GO:0048741 79 52 0,000 0,0804249 0,08964222 ! regulation of DNA replication GO:0006275 88 52 0,000 0,0804249 0,08960014 ! immunoglobulin mediated immune response GO:0016064 72 52 0,000 0,0804249 0,08955809 GO:0019724|B cell mediated immunity, ! cell recognition GO:0008037 78 52 0,000 0,0804249 0,08951608 ! covalent chromatin modification GO:0016569 90 52 0,000 0,0804249 0,08947412 ! regulation of adaptive immune response GO:0002819 90 52 0,000 0,0804249 0,08943219 ! proton transport GO:0015992 78 52 0,000 0,0804249 0,0893903 ! negative regulation of immune system process GO:0002683 90 52 0,000 0,0804249 0,08934845 ! protein amino acid autophosphorylation GO:0046777 97 52 0,000 0,0804249 0,08930664 ! transition metal ion transport GO:0000041 88 53 0,000 0,08190839 0,09091141 ! regulation of angiogenesis GO:0045765 105 53 0,000 0,08190839 0,09086891 ! muscle fiber development GO:0048747 80 53 0,000 0,08190839 0,09082645 ! sulfur compound biosynthetic process GO:0044272 71 53 0,000 0,08190839 0,09078403 ! positive regulation of phospholipase activity GO:0010518 94 53 0,000 0,08190839 0,09074164 ! cytokine-mediated signaling pathway GO:0019221 77 53 0,000 0,08190839 0,0906993 ! regulation of multicellular organism growth GO:0040014 72 53 0,000 0,08190839 0,090657 ! regulation of endocytosis GO:0030100 71 53 0,000 0,08190839 0,09061473 ! regulation of lymphocyte differentiation GO:0045619 84 53 0,000 0,08190839 0,09057251 ! glutamine family amino acid metabolic process GO:0009064 71 53 0,000 0,08190839 0,09053032 ! cellular amino acid derivative biosynthetic process GO:0042398 73 53 0,000 0,08190839 0,09048818 ! maintenance of location GO:0051235 94 53 0,000 0,08190839 0,09044607 ! hydrogen transport GO:0006818 81 54 0,000 0,08338955 0,09203879 ! response to estrogen stimulus GO:0043627 88 54 0,000 0,08338955 0,09199601 ! regulation of mitosis GO:0007088 91 54 0,000 0,08338955 0,09195326 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 100 54 0,000 0,08338955 0,09191055 ! negative regulation of cytoskeleton organization GO:0051494 96 54 0,000 0,08338955 0,09186788 ! regulation of actin polymerization or depolymerization GO:0008064 81 54 0,000 0,08338955 0,09182525 ! nucleotide-excision repair GO:0006289 70 54 0,000 0,08338955 0,09178266 ! sphingolipid metabolic process GO:0006665 80 54 0,000 0,08338955 0,09174011 ! ribonucleoprotein complex assembly GO:0022618 90 54 0,000 0,08338955 0,09169759 ! morphogenesis of a branching structure GO:0001763 99 54 0,000 0,08338955 0,09165512 ! germ cell development GO:0007281 82 54 0,000 0,08338955 0,09161269 ! positive regulation of cytokine production GO:0001819 83 54 0,000 0,08338955 0,0915703 ! regulation of protein polymerization GO:0032271 84 54 0,000 0,08338955 0,09152794 ! establishment of organelle localization GO:0051656 91 54 0,000 0,08338955 0,09148563 ! ear development GO:0043583 83 55 0,000 0,0848684 0,09306503 ! regulation of phospholipase activity GO:0010517 96 55 0,000 0,0848684 0,09302204 ! regulation of protein catabolic process GO:0042176 83 55 0,000 0,0848684 0,0929791 ! integrin-mediated signaling pathway GO:0007229 93 55 0,000 0,0848684 0,09293619 ! positive regulation of lipase activity GO:0060193 96 55 0,000 0,0848684 0,09289332 ! regulation of actin filament length GO:0030832 88 56 0,000 0,08634494 0,09446591 ! positive regulation of secretion GO:0051047 83 56 0,000 0,08634494 0,09442237 ! nucleoside metabolic process GO:0009116 74 56 0,000 0,08634494 0,09437888 ! DNA catabolic process GO:0006308 71 56 0,000 0,08634494 0,09433543 ! positive regulation of organelle organization GO:0010638 95 56 0,000 0,08634494 0,09429202 ! adult behavior GO:0030534 90 56 0,000 0,08634494 0,09424864 ! cartilage development GO:0051216 84 56 0,000 0,08634494 0,09420531 ! regulation of neurotransmitter levels GO:0001505 85 57 0,000 0,08781917 0,09576972 ! mesoderm development GO:0007498 84 57 0,000 0,08781917 0,09572572 ! nuclear export GO:0051168 85 57 0,000 0,08781917 0,09568177 ! cellular amino acid catabolic process GO:0009063 82 57 0,000 0,08781917 0,09563786 ! single fertilization GO:0007338 67 57 0,000 0,08781917 0,09559399 ! regulation of cellular component size GO:0032535 90 58 0,000 0,0892911 0,09715167 ! lipid modification GO:0030258 82 58 0,000 0,0892911 0,09710714 ! membrane lipid metabolic process GO:0006643 88 58 0,000 0,0892911 0,09706266 ! negative regulation of cell motion GO:0051271 118 58 0,000 0,0892911 0,09701822 ! regulation of bone remodeling GO:0046850 102 59 0,000 0,09076073 0,09856989 ! viral reproductive process GO:0022415 99 59 0,000 0,09076073 0,0985248 ! skeletal system morphogenesis GO:0048705 90 59 0,000 0,09076073 0,09847975 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,09076073 0,09843474 ! negative regulation of response to stimulus GO:0048585 88 59 0,000 0,09076073 0,09838977 ! regulation of lipid metabolic process GO:0019216 93 60 0,000 0,09222806 0,09993478 ! water-soluble vitamin metabolic process GO:0006767 84 60 0,000 0,09222806 0,09988917 ! response to peptide hormone stimulus GO:0043434 97 60 0,000 0,09222806 0,0998436 ! kidney development GO:0001822 101 60 0,000 0,09222806 0,09979807 ! positive regulation of cell motion GO:0051272 110 60 0,000 0,09222806 0,09975259 ! regulation of protein complex assembly GO:0043254 95 61 0,000 0,09369309 0,10129098 ! carbohydrate transport GO:0008643 83 61 0,000 0,09369309 0,10124486 ! protein maturation by peptide bond cleavage GO:0051605 86 61 0,000 0,09369309 0,10119877 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 98 62 0,000 0,09515583 0,10273194 ! amino acid transport GO:0006865 97 62 0,000 0,09515583 0,10268522 ! activation of MAPK activity GO:0000187 95 62 0,000 0,09515583 0,10263854 ! multicellular organism reproduction GO:0032504 98 62 0,000 0,09515583 0,10259191 GO:0048609|reproductive process in a multicellular organism, ! lipoprotein metabolic process GO:0042157 96 62 0,000 0,09515583 0,10254532 ! detection of external stimulus GO:0009581 78 62 0,000 0,09515583 0,10249877 ! regulation of tissue remodeling GO:0034103 113 62 0,000 0,09515583 0,10245227 ! secondary metabolic process GO:0019748 95 62 0,000 0,09515583 0,1024058 ! gonad development GO:0008406 91 62 0,000 0,09515583 0,10235938 ! exocytosis GO:0006887 91 63 0,000 0,09661629 0,10388331 ! oxygen and reactive oxygen species metabolic process GO:0006800 89 63 0,000 0,09661629 0,10383626 ! embryonic limb morphogenesis GO:0030326 96 63 0,000 0,09661629 0,10378925 GO:0035113|embryonic appendage morphogenesis, ! coenzyme biosynthetic process GO:0009108 81 63 0,000 0,09661629 0,10374229 ! regulation of heart contraction GO:0008016 104 63 0,000 0,09661629 0,10369537 ! developmental maturation GO:0021700 90 63 0,000 0,09661629 0,10364849 ! actin filament organization GO:0007015 107 64 0,000 0,09807446 0,10516525 ! fertilization GO:0009566 79 64 0,000 0,09807446 0,10511775 ! viral reproduction GO:0016032 104 64 0,000 0,09807446 0,1050703 ! myeloid cell differentiation GO:0030099 101 64 0,000 0,09807446 0,10502288 ! amine catabolic process GO:0009310 100 65 0,000 0,09953036 0,10653385 ! camera-type eye development GO:0043010 103 65 0,000 0,09953036 0,10648581 ! steroid hormone receptor signaling pathway GO:0030518 116 65 0,000 0,09953036 0,10643783 ! regulation of lipase activity GO:0060191 117 65 0,000 0,09953036 0,10638988 ! regulation of homeostatic process GO:0032844 122 65 0,000 0,09953036 0,10634198 ! organelle localization GO:0051640 105 65 0,000 0,09953036 0,10629412 ! regulation of transcription factor activity GO:0051090 109 66 0,000 0,10098397 0,10779801 GO:0090046|regulation of transcription regulator activity, ! cellular hormone metabolic process GO:0034754 95 66 0,000 0,10098397 0,10774954 ! sensory perception of smell GO:0007608 81 66 0,000 0,10098397 0,10770111 ! regulation of cytokine biosynthetic process GO:0042035 91 66 0,000 0,10098397 0,10765273 ! cAMP-mediated signaling GO:0019933 109 66 0,000 0,10098397 0,10760439 ! lung development GO:0030324 112 66 0,000 0,10098397 0,10755609 ! lymphocyte mediated immunity GO:0002449 95 66 0,000 0,10098397 0,10750784 ! B cell activation GO:0042113 119 66 0,000 0,10098397 0,10745963 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 97 66 0,000 0,10098397 0,10741146 ! protein oligomerization GO:0051259 109 66 0,000 0,10098397 0,10736334 ! cell cycle checkpoint GO:0000075 123 67 0,000 0,10243532 0,10885759 ! neurotransmitter transport GO:0006836 92 67 0,000 0,10243532 0,10880886 ! regulation of cellular response to stress GO:0080135 100 67 0,000 0,10243532 0,10876018 ! appendage morphogenesis GO:0035107 103 67 0,000 0,10243532 0,10871154 GO:0035108|limb morphogenesis, ! fatty acid biosynthetic process GO:0006633 107 67 0,000 0,10243532 0,10866294 ! extracellular matrix organization GO:0030198 117 67 0,000 0,10243532 0,10861439 ! negative regulation of ligase activity GO:0051352 100 67 0,000 0,10243532 0,10856588 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! phosphoinositide metabolic process GO:0030384 100 68 0,000 0,10388439 0,11005252 ! defense response to bacterium GO:0042742 79 68 0,000 0,10388439 0,11000342 ! regulation of vesicle-mediated transport GO:0060627 98 68 0,000 0,10388439 0,10995435 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 109 68 0,000 0,10388439 0,10990533 ! activation of immune response GO:0002253 93 68 0,000 0,10388439 0,10985635 ! appendage development GO:0048736 108 69 0,000 0,10533119 0,11133671 GO:0060173|limb development, ! respiratory tube development GO:0030323 117 69 0,000 0,10533119 0,11128714 ! urogenital system development GO:0001655 114 69 0,000 0,10533119 0,11123762 ! adaptive immune response GO:0002250 102 70 0,000 0,10677574 0,112713 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 104 71 0,000 0,10821802 0,11418469 ! cell-matrix adhesion GO:0007160 133 71 0,000 0,10821802 0,11413394 ! elevation of cytosolic calcium ion concentration GO:0007204 126 71 0,000 0,10821802 0,11408324 ! intracellular receptor-mediated signaling pathway GO:0030522 124 71 0,000 0,10821802 0,11403258 ! regulation of actin cytoskeleton organization GO:0032956 120 72 0,000 0,10965805 0,11549869 ! response to drug GO:0042493 115 72 0,000 0,10965805 0,11544745 ! cytosolic calcium ion homeostasis GO:0051480 128 72 0,000 0,10965805 0,11539625 ! homeostasis of number of cells GO:0048872 109 72 0,000 0,10965805 0,1153451 ! positive regulation of T cell activation GO:0050870 117 72 0,000 0,10965805 0,115294 ! respiratory system development GO:0060541 123 72 0,000 0,10965805 0,11524294 ! rhythmic process GO:0048511 113 72 0,000 0,10965805 0,11519192 ! regulation of immune effector process GO:0002697 121 72 0,000 0,10965805 0,11514095 ! learning or memory GO:0007611 132 73 0,000 0,11109582 0,11659902 ! humoral immune response GO:0006959 93 73 0,000 0,11109582 0,11654748 ! regulation of MAPKKK cascade GO:0043408 123 73 0,000 0,11109582 0,11649597 ! acute inflammatory response GO:0002526 107 74 0,000 0,11253135 0,11794916 ! activation of protein kinase activity GO:0032147 115 74 0,000 0,11253135 0,11789708 ! regulation of actin filament-based process GO:0032970 122 74 0,000 0,11253135 0,11784505 ! development of primary sexual characteristics GO:0045137 107 74 0,000 0,11253135 0,11779307 ! transcription initiation from RNA polymerase II promoter GO:0006367 100 74 0,000 0,11253135 0,11774113 ! regulation of neuron differentiation GO:0045664 130 74 0,000 0,11253135 0,11768924 ! regulation of Rho protein signal transduction GO:0035023 126 74 0,000 0,11253135 0,1176374 ! regulation of synaptic transmission GO:0050804 117 74 0,000 0,11253135 0,1175856 ! leukocyte mediated immunity GO:0002443 107 75 0,000 0,11396463 0,11903084 ! inorganic anion transport GO:0015698 109 75 0,000 0,11396463 0,11897847 ! lymphocyte differentiation GO:0030098 135 75 0,000 0,11396463 0,11892615 ! regulation of catabolic process GO:0009894 114 75 0,000 0,11396463 0,11887387 ! cell-substrate adhesion GO:0031589 141 76 0,000 0,11539566 0,12031367 ! regulation of Ras GTPase activity GO:0032318 125 76 0,000 0,11539566 0,12026083 ! negative regulation of transport GO:0051051 122 77 0,000 0,11682446 0,12169642 ! cellular lipid catabolic process GO:0044242 117 77 0,000 0,11682446 0,12164302 ! response to nutrient GO:0007584 114 77 0,000 0,11682446 0,12158967 ! regulation of blood pressure GO:0008217 119 78 0,000 0,11825102 0,12302046 ! muscle cell differentiation GO:0042692 117 78 0,000 0,11825102 0,12296656 ! amine transport GO:0015837 115 78 0,000 0,11825102 0,12291269 ! antigen processing and presentation GO:0019882 114 78 0,000 0,11825102 0,12285888 ! steroid biosynthetic process GO:0006694 111 79 0,000 0,11967535 0,1242843 ! regulation of adenylate cyclase activity GO:0045761 143 80 0,000 0,12109745 0,12570615 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 123 80 0,000 0,12109745 0,12565118 ! regulation of DNA binding GO:0051101 130 80 0,000 0,12109745 0,12559627 ! tube morphogenesis GO:0035239 140 80 0,000 0,12109745 0,1255414 ! eye development GO:0001654 130 80 0,000 0,12109745 0,12548658 ! intracellular protein transmembrane transport GO:0065002 115 80 0,000 0,12109745 0,1254318 ! protein ubiquitination GO:0016567 135 80 0,000 0,12109745 0,12537708 ! negative regulation of organelle organization GO:0010639 136 80 0,000 0,12109745 0,1253224 ! regulation of transmission of nerve impulse GO:0051969 126 80 0,000 0,12109745 0,12526777 ! response to steroid hormone stimulus GO:0048545 129 80 0,000 0,12109745 0,12521318 ! cellular response to hormone stimulus GO:0032870 125 80 0,000 0,12109745 0,12515865 ! blood coagulation GO:0007596 129 81 0,000 0,12251733 0,12657102 GO:0050817|coagulation, ! amine biosynthetic process GO:0009309 108 81 0,000 0,12251733 0,12651594 ! oxidative phosphorylation GO:0006119 110 81 0,000 0,12251733 0,12646091 ! nitrogen compound catabolic process GO:0044270 125 81 0,000 0,12251733 0,12640592 ! response to hypoxia GO:0001666 155 81 0,000 0,12251733 0,12635099 ! regulation of protein transport GO:0051223 123 81 0,000 0,12251733 0,1262961 GO:0070201|regulation of establishment of protein localization, ! regulation of cAMP biosynthetic process GO:0030817 148 82 0,000 0,12393498 0,127702 ! neuropeptide signaling pathway GO:0007218 101 82 0,000 0,12393498 0,12764658 ! regulation of cell morphogenesis GO:0022604 155 82 0,000 0,12393498 0,1275912 ! regulation of cyclase activity GO:0031279 146 82 0,000 0,12393498 0,12753587 ! cholesterol metabolic process GO:0008203 120 83 0,000 0,12535042 0,12893651 ! response to oxygen levels GO:0070482 160 83 0,000 0,12535042 0,12888065 ! regulation of cell cycle process GO:0010564 139 83 0,000 0,12535042 0,12882483 ! regulation of lyase activity GO:0051339 147 83 0,000 0,12535042 0,12876906 ! regulation of cAMP metabolic process GO:0030814 153 84 0,000 0,12676363 0,13016448 ! digestion GO:0007586 111 84 0,000 0,12676363 0,13010818 ! regulation of neurological system process GO:0031644 133 84 0,000 0,12676363 0,13005193 ! ATP biosynthetic process GO:0006754 131 84 0,000 0,12676363 0,12999572 ! cellular respiration GO:0045333 119 85 0,000 0,12817464 0,13138593 ! biogenic amine metabolic process GO:0006576 128 85 0,000 0,12817464 0,1313292 ! T cell activation GO:0042110 154 85 0,000 0,12817464 0,13127252 ! sex differentiation GO:0007548 126 85 0,000 0,12817464 0,13121588 ! protein import into nucleus GO:0006606 145 85 0,000 0,12817464 0,1311593 ! one-carbon metabolic process GO:0006730 126 85 0,000 0,12817464 0,13110277 ! carbohydrate biosynthetic process GO:0016051 111 86 0,000 0,12958344 0,13248664 ! regulation of nucleotide biosynthetic process GO:0030808 155 87 0,000 0,13099003 0,13386707 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! hemostasis GO:0007599 138 87 0,000 0,13099003 0,13380944 ! regulation of defense response GO:0031347 135 87 0,000 0,13099003 0,13375187 ! Golgi vesicle transport GO:0048193 145 87 0,000 0,13099003 0,13369434 ! sensory perception of chemical stimulus GO:0007606 108 87 0,000 0,13099003 0,13363686 ! gland development GO:0048732 170 87 0,000 0,13099003 0,13357943 ! vitamin metabolic process GO:0006766 117 87 0,000 0,13099003 0,13352205 ! forebrain development GO:0030900 151 87 0,000 0,13099003 0,13346472 ! regulation of membrane potential GO:0042391 144 88 0,000 0,13239442 0,13483775 ! ossification GO:0001503 150 89 0,000 0,13379661 0,13620736 GO:0060348|bone development, ! nucleosome assembly GO:0006334 113 89 0,000 0,13379661 0,13614895 GO:0031497|chromatin assembly, ! regulation of DNA metabolic process GO:0051052 152 90 0,000 0,1351966 0,13751459 ! regulation of cyclic nucleotide metabolic process GO:0030799 161 90 0,000 0,1351966 0,13745567 ! skeletal muscle tissue development GO:0007519 135 90 0,000 0,1351966 0,13739681 GO:0060538|skeletal muscle organ development, ! transcription initiation GO:0006352 128 90 0,000 0,1351966 0,13733799 ! regulation of GTPase activity GO:0043087 149 90 0,000 0,1351966 0,13727922 ! nuclear import GO:0051170 153 90 0,000 0,1351966 0,13722051 ! regulation of protein localization GO:0032880 141 90 0,000 0,1351966 0,13716184 ! carboxylic acid catabolic process GO:0046395 132 91 0,000 0,13659441 0,13852074 GO:0016054|organic acid catabolic process, ! detection of stimulus GO:0051606 123 91 0,000 0,13659441 0,13846157 ! protein localization in nucleus GO:0034504 161 92 0,000 0,13799002 0,13981653 ! sterol metabolic process GO:0016125 136 92 0,000 0,13799002 0,13975686 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 141 93 0,000 0,13938345 0,14110791 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! protein-DNA complex assembly GO:0065004 119 93 0,000 0,13938345 0,14104773 ! rRNA processing GO:0006364 124 93 0,000 0,13938345 0,14098761 ! positive regulation of MAP kinase activity GO:0043406 143 93 0,000 0,13938345 0,14092754 ! regulation of nucleotide metabolic process GO:0006140 164 93 0,000 0,13938345 0,14086752 ! anterior/posterior pattern formation GO:0009952 141 93 0,000 0,13938345 0,14080755 ! negative regulation of multicellular organismal process GO:0051241 150 93 0,000 0,13938345 0,14074763 ! leukocyte differentiation GO:0002521 165 94 0,000 0,1407747 0,14209203 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 140 94 0,000 0,1407747 0,14203161 ! ribonucleoside triphosphate biosynthetic process GO:0009201 142 94 0,000 0,1407747 0,14197125 ! rRNA metabolic process GO:0016072 125 94 0,000 0,1407747 0,14191094 ! regulation of cell adhesion GO:0030155 187 94 0,000 0,1407747 0,14185068 ! hormone metabolic process GO:0042445 135 94 0,000 0,1407747 0,14179047 ! protein processing GO:0016485 127 94 0,000 0,1407747 0,14173032 ! nucleoside triphosphate biosynthetic process GO:0009142 143 95 0,000 0,14216377 0,14306812 ! anatomical structure homeostasis GO:0060249 152 95 0,000 0,14216377 0,14300747 ! ATP metabolic process GO:0046034 150 96 0,000 0,14355066 0,1443414 ! nucleosome organization GO:0034728 126 96 0,000 0,14355066 0,14428027 ! protein modification by small protein conjugation GO:0032446 153 96 0,000 0,14355066 0,14421918 ! female pregnancy GO:0007565 148 96 0,000 0,14355066 0,14415815 ! regulation of neurogenesis GO:0050767 179 97 0,000 0,14493538 0,14548716 ! reproductive developmental process GO:0003006 149 97 0,000 0,14493538 0,14542565 ! response to virus GO:0009615 141 98 0,000 0,14631793 0,14675082 ! polysaccharide metabolic process GO:0005976 141 98 0,000 0,14631793 0,14668882 ! Wnt receptor signaling pathway GO:0016055 161 98 0,000 0,14631793 0,14662688 ! regulation of T cell activation GO:0050863 155 98 0,000 0,14631793 0,14656498 ! regulation of binding GO:0051098 164 99 0,000 0,14769831 0,14788527 ! electron transport chain GO:0022900 135 99 0,000 0,14769831 0,1478229 ! cell fate commitment GO:0045165 165 99 0,000 0,14769831 0,14776058 ! positive regulation of immune response GO:0050778 143 99 0,000 0,14769831 0,14769831