pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/23438-2-real-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 4,000 1,614E-08 3,712E-05 ! substrate-bound cell migration, cell extension GO:0006930 5 5 2,000 3,672E-08 4,222E-05 ! substrate-bound cell migration GO:0006929 10 9 2,000 3,071E-07 2,354E-04 ! glycolysis GO:0006096 53 44 3,000 6,837E-07 3,931E-04 ! glucose catabolic process GO:0006007 66 54 3,000 1,575E-06 7,247E-04 ! hexose catabolic process GO:0019320 82 64 3,000 3,13E-06 1,2E-03 ! monosaccharide catabolic process GO:0046365 91 71 3,000 4,75E-06 1,561E-03 ! alcohol catabolic process GO:0046164 104 80 3,000 7,657E-06 2,201E-03 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 2,000 9,334E-06 2,385E-03 ! carbohydrate catabolic process GO:0016052 121 93 3,000 1,393E-05 3,205E-03 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 2,000 2,13E-05 4,453E-03 ! positive regulation of viral genome replication GO:0045070 8 5 1,000 2,466E-05 4,727E-03 ! regulation of retroviral genome replication GO:0045091 6 5 1,000 2,466E-05 4,364E-03 ! amino acid activation GO:0043038 52 37 2,000 2,757E-05 4,529E-03 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 3,494E-05 5,357E-03 ! JAK-STAT cascade GO:0007259 53 40 2,000 3,494E-05 5,023E-03 ! cysteine metabolic process GO:0006534 7 6 1,000 3,696E-05 5E-03 ! DNA topological change GO:0006265 8 6 1,000 3,696E-05 4,723E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 4,35E-05 5,266E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 5,169E-05 5,945E-03 ! response to UV GO:0009411 75 46 2,000 5,334E-05 5,842E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 6,886E-05 7,199E-03 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 6,886E-05 6,886E-03 ! keratinocyte proliferation GO:0043616 12 8 1,000 6,886E-05 6,599E-03 ! aging GO:0007568 79 52 2,000 7,715E-05 7,098E-03 ! glycerophospholipid biosynthetic process GO:0046474 75 53 2,000 8,17E-05 7,227E-03 ! cell projection assembly GO:0030031 76 53 2,000 8,17E-05 6,959E-03 ! DNA ligation GO:0006266 14 9 1,000 8,844E-05 7,265E-03 ! negative regulation of protein kinase activity GO:0006469 99 57 2,000 1,016E-04 8,058E-03 ! negative regulation of kinase activity GO:0033673 100 58 2,000 1,07E-04 8,206E-03 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,104E-04 8,194E-03 ! positive regulation of viral reproduction GO:0048524 15 10 1,000 1,104E-04 7,938E-03 ! glycerolipid biosynthetic process GO:0045017 85 60 2,000 1,184E-04 8,255E-03 ! negative regulation of transferase activity GO:0051348 105 61 2,000 1,244E-04 8,418E-03 ! axon guidance GO:0007411 99 66 2,000 1,574E-04 0,0103419 ! positive regulation of cell growth GO:0030307 16 12 1,000 1,617E-04 0,01032825 ! phosphoinositide-mediated signaling GO:0048015 109 71 2,000 1,955E-04 0,01215369 ! phospholipid biosynthetic process GO:0008654 102 74 2,000 2,21E-04 0,01337865 ! negative regulation of caspase activity GO:0043154 20 14 1,000 2,225E-04 0,01311901 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 2,225E-04 0,01279103 ! tRNA metabolic process GO:0006399 95 76 2,000 2,392E-04 0,01341841 ! response to unfolded protein GO:0006986 99 76 2,000 2,392E-04 0,01309892 ! positive regulation of cell size GO:0045793 20 15 1,000 2,564E-04 0,01371559 ! skin development GO:0043588 25 15 1,000 2,564E-04 0,01340387 ! response to protein stimulus GO:0051789 111 81 2,000 2,888E-04 0,01475849 ! cellular response to unfolded protein GO:0034620 19 16 1,000 2,928E-04 0,01463817 GO:0030968|endoplasmic reticulum unfolded protein response, ! negative regulation of peptidase activity GO:0010466 23 17 1,000 3,315E-04 0,01622087 ! regulation of viral genome replication GO:0045069 24 17 1,000 3,315E-04 0,01588293 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 3,445E-04 0,01617065 ! interphase GO:0051325 159 88 2,000 3,686E-04 0,01695614 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 3,725E-04 0,01680056 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 4,159E-04 0,01839777 ! apoptotic nuclear changes GO:0030262 24 19 1,000 4,159E-04 0,01805064 ! glycerophospholipid metabolic process GO:0006650 130 92 2,000 4,2E-04 0,01789017 ! chromosome condensation GO:0030261 31 20 1,000 4,617E-04 0,01930781 ! positive regulation of B cell activation GO:0050871 31 20 1,000 4,617E-04 0,01896303 ! response to light stimulus GO:0009416 153 96 2,000 4,759E-04 0,01920103 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 5,098E-04 0,02021637 ! sulfur amino acid metabolic process GO:0000096 24 21 1,000 5,098E-04 0,01987372 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 5,098E-04 0,01954249 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 1,000 5,098E-04 0,01922212 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 5,098E-04 0,01891209 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 5,602E-04 0,02045281 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 6,13E-04 0,02202886 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 6,13E-04 0,02168995 ! regulation of viral reproduction GO:0050792 32 23 1,000 6,13E-04 0,02136132 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 6,13E-04 0,02104249 ! fat cell differentiation GO:0045444 37 24 1,000 6,68E-04 0,02259548 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 7,254E-04 0,0241804 GO:0045936|negative regulation of phosphate metabolic process, ! serine family amino acid metabolic process GO:0009069 37 27 1,000 8,471E-04 0,02783173 ! regulation of B cell activation GO:0050864 42 28 1,000 9,113E-04 0,02952124 ! spindle organization GO:0007051 37 30 1,000 1,047E-03 0,03343475 ! meiosis I GO:0007127 52 32 1,000 1,191E-03 0,03752671 ! nucleus organization GO:0006997 49 33 1,000 1,267E-03 0,03936897 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 1,267E-03 0,03884405 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 1,344E-03 0,04068847 ! keratinocyte differentiation GO:0030216 47 35 1,000 1,425E-03 0,04255186 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 1,425E-03 0,04200632 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! response to calcium ion GO:0051592 58 40 1,000 1,858E-03 0,0541018 ! epidermal cell differentiation GO:0009913 53 40 1,000 1,858E-03 0,05342552 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 2,245E-03 0,06374299 ! positive regulation of cell cycle GO:0045787 77 45 1,000 2,347E-03 0,06582915 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 2,558E-03 0,07087383 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of growth GO:0045927 67 50 1,000 2,89E-03 0,07912385 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 3,611E-03 0,09771876 ! chromosome segregation GO:0007059 83 57 1,000 3,739E-03 0,09999577 ! meiosis GO:0007126 96 61 1,000 4,27E-03 0,11289212 GO:0051327|M phase of meiotic cell cycle, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 4,27E-03 0,11160925 ! negative regulation of cell growth GO:0030308 106 62 1,000 4,408E-03 0,1139212 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 4,408E-03 0,11265541 ! meiotic cell cycle GO:0051321 97 62 1,000 4,408E-03 0,11141744 ! negative regulation of cell size GO:0045792 108 64 1,000 4,69E-03 0,11725957 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 4,69E-03 0,11599872 ! regulation of caspase activity GO:0043281 97 65 1,000 4,835E-03 0,1182912 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 4,835E-03 0,11704603 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 4,835E-03 0,1158268 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 5,129E-03 0,12161209 ! positive regulation of ligase activity GO:0051351 99 69 1,000 5,431E-03 0,12746901 ! response to metal ion GO:0010038 103 70 1,000 5,586E-03 0,12976457 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 5,586E-03 0,12846693 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 5,742E-03 0,13075274 ! regulation of peptidase activity GO:0052547 106 72 1,000 5,9E-03 0,13303871 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 5,9E-03 0,13174708 GO:0045937|positive regulation of phosphate metabolic process, ! mitochondrion organization GO:0007005 104 73 1,000 6,06E-03 0,13402352 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 6,222E-03 0,13630003 ! response to inorganic substance GO:0010035 115 75 1,000 6,387E-03 0,13857647 ! negative regulation of growth GO:0045926 123 75 1,000 6,387E-03 0,13728136 ! regulation of ligase activity GO:0051340 114 75 1,000 6,387E-03 0,13601024 ! cofactor biosynthetic process GO:0051188 92 75 1,000 6,387E-03 0,13476244 ! positive regulation of protein modification process GO:0031401 107 78 1,000 6,891E-03 0,14408221 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 7,237E-03 0,14995314 GO:0010498|proteasomal protein catabolic process, ! positive regulation of cell activation GO:0050867 120 81 1,000 7,413E-03 0,15222654 GO:0002696|positive regulation of leukocyte activation, ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 7,952E-03 0,16185582 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 7,984E-03 0,16107134 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 7,984E-03 0,15967072 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 7,984E-03 0,15829424 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 7,984E-03 0,1569413 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 7,984E-03 0,15561129 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 7,984E-03 0,15430363 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 7,984E-03 0,15301777 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 7,984E-03 0,15175316 ! sleep GO:0030431 11 5 0,000 7,984E-03 0,15050928 ! negative regulation of bone resorption GO:0045779 10 5 0,000 7,984E-03 0,14928563 ! nucleotide-sugar transport GO:0015780 8 5 0,000 7,984E-03 0,14808171 ! regulation of interferon-beta production GO:0032648 5 5 0,000 7,984E-03 0,14689706 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 7,984E-03 0,14573121 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 7,984E-03 0,14458372 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 7,984E-03 0,14345416 ! tongue development GO:0043586 6 5 0,000 7,984E-03 0,14234211 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 7,984E-03 0,14124717 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 7,984E-03 0,14016895 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 7,984E-03 0,13910706 ! cobalt ion transport GO:0006824 9 5 0,000 7,984E-03 0,13806115 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 7,984E-03 0,13703084 ! SMAD protein complex assembly GO:0007183 9 5 0,000 7,984E-03 0,1360158 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 7,984E-03 0,13501568 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 7,984E-03 0,13403016 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 7,984E-03 0,13305893 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 7,984E-03 0,13210167 ! embryonic camera-type eye development GO:0031076 8 5 0,000 7,984E-03 0,13115809 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 7,984E-03 0,13022789 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 7,984E-03 0,12931079 ! adaptation of signaling pathway GO:0022401 7 5 0,000 7,984E-03 0,12840652 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 7,984E-03 0,12751481 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 7,984E-03 0,1266354 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 7,984E-03 0,12576803 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 7,984E-03 0,12491247 ! positive regulation of histone modification GO:0031058 5 5 0,000 7,984E-03 0,12406846 ! malate metabolic process GO:0006108 7 5 0,000 7,984E-03 0,12323579 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 7,984E-03 0,12241422 ! behavioral response to pain GO:0048266 7 5 0,000 7,984E-03 0,12160353 ! clathrin coat assembly GO:0048268 11 5 0,000 7,984E-03 0,1208035 ! phototransduction, visible light GO:0007603 6 5 0,000 7,984E-03 0,12001394 ! regulation of dopamine uptake GO:0051584 9 5 0,000 7,984E-03 0,11923463 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 7,984E-03 0,11846537 ! mating behavior GO:0007617 6 5 0,000 7,984E-03 0,11770598 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 7,984E-03 0,11695626 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 7,984E-03 0,11621603 ! rhythmic behavior GO:0007622 12 5 0,000 7,984E-03 0,11548511 ! copulation GO:0007620 7 5 0,000 7,984E-03 0,11476333 ! glial cell fate commitment GO:0021781 12 5 0,000 7,984E-03 0,11405051 ! protein maturation by protein folding GO:0022417 12 5 0,000 7,984E-03 0,1133465 ! embryonic hemopoiesis GO:0035162 10 5 0,000 7,984E-03 0,11265112 ! regulation of potassium ion transport GO:0043266 9 5 0,000 7,984E-03 0,11196422 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 7,984E-03 0,11128565 ! apoptotic cell clearance GO:0043277 13 5 0,000 7,984E-03 0,11061526 ! lipoprotein particle clearance GO:0034381 9 5 0,000 7,984E-03 0,10995289 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 7,984E-03 0,10929841 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 7,984E-03 0,10865167 ! response to protozoan GO:0001562 9 5 0,000 7,984E-03 0,10801254 ! positive regulation of glycolysis GO:0045821 11 5 0,000 7,984E-03 0,10738089 ! lymph vessel development GO:0001945 7 5 0,000 7,984E-03 0,10675658 ! endochondral ossification GO:0001958 12 5 0,000 7,984E-03 0,10613949 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 7,984E-03 0,1055295 ! parathyroid gland development GO:0060017 8 5 0,000 7,984E-03 0,10492647 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 7,984E-03 0,1043303 ! anagen GO:0042640 6 5 0,000 7,984E-03 0,10374086 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 7,984E-03 0,10315805 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 7,984E-03 0,10258175 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 7,984E-03 0,10201185 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 7,984E-03 0,10144825 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 7,984E-03 0,10089084 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 7,984E-03 0,10033952 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 7,984E-03 0,0997942 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 7,984E-03 0,09925477 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 7,984E-03 0,09872114 ! cardiac muscle fiber development GO:0048739 7 5 0,000 7,984E-03 0,09819322 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 7,984E-03 0,09767092 ! neutrophil mediated immunity GO:0002446 6 5 0,000 7,984E-03 0,09715414 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 7,984E-03 0,0966428 ! ovulation GO:0030728 6 5 0,000 7,984E-03 0,09613682 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 7,984E-03 0,09563611 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 7,984E-03 0,09514058 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 7,984E-03 0,09465017 ! response to pH GO:0009268 9 5 0,000 7,984E-03 0,09416478 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 7,984E-03 0,09368435 ! proline biosynthetic process GO:0006561 6 5 0,000 7,984E-03 0,09320879 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 7,984E-03 0,09273804 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 7,984E-03 0,09227202 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 7,984E-03 0,09181066 ! polyol catabolic process GO:0046174 7 5 0,000 7,984E-03 0,09135389 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 7,984E-03 0,09090165 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 7,984E-03 0,09045385 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 7,984E-03 0,09001045 ! sister chromatid cohesion GO:0007062 9 5 0,000 7,984E-03 0,08957138 ! nerve growth factor processing GO:0032455 7 5 0,000 7,984E-03 0,08913657 ! urea metabolic process GO:0019627 6 5 0,000 7,984E-03 0,08870595 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 7,984E-03 0,08827948 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 7,984E-03 0,08785709 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 7,984E-03 0,08743873 ! neutrophil activation GO:0042119 5 5 0,000 7,984E-03 0,08702432 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 7,984E-03 0,08661383 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 7,984E-03 0,08620719 ! response to food GO:0032094 5 5 0,000 7,984E-03 0,08580436 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 7,984E-03 0,08540527 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 7,984E-03 0,08500987 ! paraxial mesoderm development GO:0048339 9 5 0,000 7,984E-03 0,08461812 ! forebrain neuron development GO:0021884 7 5 0,000 7,984E-03 0,08422997 ! melanosome organization GO:0032438 7 5 0,000 7,984E-03 0,08384535 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 7,984E-03 0,08346424 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 7,984E-03 0,08308657 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 7,984E-03 0,08271231 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 7,984E-03 0,0823414 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 7,984E-03 0,08197381 ! nucleoside transport GO:0015858 6 5 0,000 7,984E-03 0,08160948 ! nucleoside salvage GO:0043174 7 5 0,000 7,984E-03 0,08124837 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 7,984E-03 0,08089045 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 7,984E-03 0,08053567 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 7,984E-03 0,08018398 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 7,984E-03 0,07983536 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 7,984E-03 0,07948975 ! early endosome to late endosome transport GO:0045022 11 5 0,000 7,984E-03 0,07914712 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 7,984E-03 0,07880744 ! depyrimidination GO:0045008 8 5 0,000 7,984E-03 0,07847065 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 7,984E-03 0,07813673 ! 5S class rRNA transcription GO:0042791 8 5 0,000 7,984E-03 0,07780565 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 7,984E-03 0,07747735 ! regulation of centrosome cycle GO:0046605 7 5 0,000 7,984E-03 0,07715182 ! neuronal ion channel clustering GO:0045161 7 5 0,000 7,984E-03 0,07682901 ! sodium ion homeostasis GO:0055078 6 5 0,000 7,984E-03 0,07650888 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 7,984E-03 0,07619142 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 7,984E-03 0,07587658 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 7,984E-03 0,07556433 ! monocyte differentiation GO:0030224 8 5 0,000 7,984E-03 0,07525464 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 7,984E-03 0,07494748 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 7,984E-03 0,07464281 ! centrosome duplication GO:0051298 5 5 0,000 7,984E-03 0,07434062 ! response to UV-C GO:0010225 6 5 0,000 7,984E-03 0,07404086 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 7,984E-03 0,0737435 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 7,984E-03 0,07344853 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 7,984E-03 0,07315591 ! regulation of dendrite development GO:0050773 12 5 0,000 7,984E-03 0,0728656 ! peptidyl-arginine modification GO:0018195 7 5 0,000 7,984E-03 0,0725776 ! positive regulation of organ growth GO:0046622 6 5 0,000 7,984E-03 0,07229186 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 7,984E-03 0,07200836 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 7,984E-03 0,07172708 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 7,984E-03 0,07144799 ! regulation of dopamine secretion GO:0014059 12 5 0,000 7,984E-03 0,07117106 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 7,984E-03 0,07089626 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 7,984E-03 0,07062359 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 7,984E-03 0,070353 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 7,984E-03 0,07008447 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 7,984E-03 0,06981799 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 7,984E-03 0,06955353 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 7,984E-03 0,06929107 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 7,984E-03 0,06903057 ! neural tube patterning GO:0021532 6 5 0,000 7,984E-03 0,06877203 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 7,984E-03 0,06851542 ! histone demethylation GO:0016577 9 5 0,000 7,984E-03 0,06826072 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 7,984E-03 0,0680079 ! regulation of sterol transport GO:0032371 7 5 0,000 7,984E-03 0,06775695 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 7,984E-03 0,06750784 ! enteric nervous system development GO:0048484 8 5 0,000 7,984E-03 0,06726056 ! establishment of planar polarity GO:0001736 6 5 0,000 7,984E-03 0,06701508 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 7,984E-03 0,06677139 ! muscle cell proliferation GO:0033002 8 5 0,000 7,984E-03 0,06652947 ! transcription termination GO:0006353 8 5 0,000 7,984E-03 0,06628929 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 7,984E-03 0,06605084 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 7,984E-03 0,06581409 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 7,984E-03 0,06557904 ! regulation of respiratory burst GO:0060263 8 5 0,000 7,984E-03 0,06534567 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 7,984E-03 0,06511394 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 7,984E-03 0,06488386 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 7,984E-03 0,0646554 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 7,984E-03 0,06442853 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 7,984E-03 0,06420326 ! apical protein localization GO:0045176 6 5 0,000 7,984E-03 0,06397956 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 7,984E-03 0,0637574 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 7,984E-03 0,06353679 ! galactolipid metabolic process GO:0019374 7 5 0,000 7,984E-03 0,0633177 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 7,984E-03 0,06310011 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 7,984E-03 0,06288402 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 7,984E-03 0,06266939 ! triglyceride catabolic process GO:0019433 6 5 0,000 7,984E-03 0,06245623 ! glial cell migration GO:0008347 10 5 0,000 7,984E-03 0,06224452 ! determination of adult lifespan GO:0008340 8 5 0,000 7,984E-03 0,06203423 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 7,984E-03 0,06182536 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 7,984E-03 0,06161789 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 7,984E-03 0,06141181 ! somatic stem cell maintenance GO:0035019 13 5 0,000 7,984E-03 0,06120711 ! cerebellar cortex formation GO:0021697 6 5 0,000 7,984E-03 0,06100376 ! neural plate development GO:0001840 6 5 0,000 7,984E-03 0,06080176 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 7,984E-03 0,0606011 ! regulation of sensory perception GO:0051931 6 5 0,000 7,984E-03 0,06040175 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 7,984E-03 0,06020371 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 7,984E-03 0,06000697 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 7,984E-03 0,05981151 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 7,984E-03 0,05961731 ! sensory cilium assembly GO:0035058 6 5 0,000 7,984E-03 0,05942438 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 7,984E-03 0,05923269 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 7,984E-03 0,05904223 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 7,984E-03 0,05885299 ! spindle assembly GO:0051225 5 5 0,000 7,984E-03 0,05866496 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 7,984E-03 0,05847813 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 7,984E-03 0,05829248 ! protein amino acid prenylation GO:0018346 9 5 0,000 7,984E-03 0,05810801 ! organ regeneration GO:0031100 7 5 0,000 7,984E-03 0,05792471 ! NAD biosynthetic process GO:0009435 7 5 0,000 7,984E-03 0,05774255 ! carnitine metabolic process GO:0009437 5 5 0,000 7,984E-03 0,05756154 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 7,984E-03 0,05738166 ! cellular anion homeostasis GO:0030002 6 5 0,000 7,984E-03 0,0572029 GO:0055081|anion homeostasis, ! cell cycle arrest GO:0007050 150 86 1,000 8,321E-03 0,05943675 ! sulfur metabolic process GO:0006790 118 92 1,000 9,474E-03 0,06746114 ! tRNA transcription GO:0009304 11 6 0,000 9,573E-03 0,06795542 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 9,573E-03 0,06774633 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 9,573E-03 0,06753852 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 9,573E-03 0,06733198 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 9,573E-03 0,0671267 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 9,573E-03 0,06692267 ! regulation of helicase activity GO:0051095 11 6 0,000 9,573E-03 0,06671987 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 9,573E-03 0,0665183 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 9,573E-03 0,06631794 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 9,573E-03 0,06611879 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 9,573E-03 0,06592083 ! positive regulation of axon extension GO:0045773 8 6 0,000 9,573E-03 0,06572405 ! prostate gland development GO:0030850 9 6 0,000 9,573E-03 0,06552844 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 9,573E-03 0,065334 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 9,573E-03 0,0651407 ! forebrain neuron differentiation GO:0021879 9 6 0,000 9,573E-03 0,06494855 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 9,573E-03 0,06475752 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 9,573E-03 0,06456762 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 9,573E-03 0,06437882 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 9,573E-03 0,06419113 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 9,573E-03 0,06400453 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 9,573E-03 0,06381901 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 9,573E-03 0,06363456 ! neuron adhesion GO:0007158 9 6 0,000 9,573E-03 0,06345117 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 9,573E-03 0,06326884 ! establishment of tissue polarity GO:0007164 7 6 0,000 9,573E-03 0,06308756 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 9,573E-03 0,06290731 ! signal peptide processing GO:0006465 8 6 0,000 9,573E-03 0,06272808 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 9,573E-03 0,06254988 ! mRNA stabilization GO:0048255 15 6 0,000 9,573E-03 0,06237268 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 9,573E-03 0,06219649 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 9,573E-03 0,06202129 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 9,573E-03 0,06184707 ! opsonization GO:0008228 8 6 0,000 9,573E-03 0,06167383 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 9,573E-03 0,06150156 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 9,573E-03 0,06133024 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 9,573E-03 0,06115988 ! protein amino acid dealkylation GO:0008214 11 6 0,000 9,573E-03 0,06099046 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 9,573E-03 0,06082198 ! photoreceptor cell development GO:0042461 10 6 0,000 9,573E-03 0,06065443 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 9,573E-03 0,06048779 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 9,573E-03 0,06032207 ! mechanosensory behavior GO:0007638 8 6 0,000 9,573E-03 0,06015726 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 9,573E-03 0,05999334 ! negative regulation of endocytosis GO:0045806 8 6 0,000 9,573E-03 0,05983032 ! response to interferon-gamma GO:0034341 12 6 0,000 9,573E-03 0,05966818 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 9,573E-03 0,05950691 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 9,573E-03 0,05934652 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 9,573E-03 0,05918698 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 9,573E-03 0,0590283 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 9,573E-03 0,05887047 ! cGMP-mediated signaling GO:0019934 10 6 0,000 9,573E-03 0,05871349 ! activation of MAPKKK activity GO:0000185 10 6 0,000 9,573E-03 0,05855733 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 9,573E-03 0,05840201 ! thymic T cell selection GO:0045061 12 6 0,000 9,573E-03 0,05824751 ! protein lipoylation GO:0009249 10 6 0,000 9,573E-03 0,05809382 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 9,573E-03 0,05794094 ! pigment granule organization GO:0048753 11 6 0,000 9,573E-03 0,05778886 ! drug transport GO:0015893 6 6 0,000 9,573E-03 0,05763758 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 9,573E-03 0,05748709 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 9,573E-03 0,05733739 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 9,573E-03 0,05718846 ! histidine metabolic process GO:0006547 6 6 0,000 9,573E-03 0,0570403 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 9,573E-03 0,05689291 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 9,573E-03 0,05674628 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 9,573E-03 0,0566004 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 9,573E-03 0,05645528 ! adenohypophysis development GO:0021984 10 6 0,000 9,573E-03 0,05631089 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 9,573E-03 0,05616724 ! hyperosmotic response GO:0006972 8 6 0,000 9,573E-03 0,05602432 ! microtubule nucleation GO:0007020 10 6 0,000 9,573E-03 0,05588213 ! ER overload response GO:0006983 7 6 0,000 9,573E-03 0,05574065 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 9,573E-03 0,05559989 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 9,573E-03 0,05545984 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 9,573E-03 0,0553205 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 9,573E-03 0,05518185 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 9,573E-03 0,05504389 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 9,573E-03 0,05490663 ! response to dietary excess GO:0002021 7 6 0,000 9,573E-03 0,05477004 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 9,573E-03 0,05463414 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 9,573E-03 0,0544989 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 9,573E-03 0,05436434 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 9,573E-03 0,05423044 ! glycerol ether catabolic process GO:0044269 8 6 0,000 9,573E-03 0,05409719 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 9,573E-03 0,0539646 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 9,573E-03 0,05383266 ! neuron apoptosis GO:0051402 8 6 0,000 9,573E-03 0,05370136 ! organic alcohol transport GO:0015850 9 6 0,000 9,573E-03 0,0535707 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 9,573E-03 0,05344067 ! T cell mediated immunity GO:0002456 12 6 0,000 9,573E-03 0,05331128 ! male sex determination GO:0030238 9 6 0,000 9,573E-03 0,05318251 ! carnitine transport GO:0015879 8 6 0,000 9,573E-03 0,05305435 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 9,573E-03 0,05292682 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 9,573E-03 0,0527999 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 9,573E-03 0,05267358 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 9,573E-03 0,05254787 ! positive regulation of exocytosis GO:0045921 6 6 0,000 9,573E-03 0,05242276 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 9,573E-03 0,05229824 ! parturition GO:0007567 12 6 0,000 9,573E-03 0,05217431 ! negative regulation of translational initiation GO:0045947 7 6 0,000 9,573E-03 0,05205096 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 9,573E-03 0,0519282 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 9,573E-03 0,05180602 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 9,573E-03 0,05168441 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 9,573E-03 0,05156337 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 9,573E-03 0,05144289 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 9,573E-03 0,05132298 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 9,573E-03 0,05120362 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 9,573E-03 0,05108482 ! macrophage differentiation GO:0030225 10 6 0,000 9,573E-03 0,05096657 ! astrocyte development GO:0014002 14 6 0,000 9,573E-03 0,05084886 ! hyaluronan metabolic process GO:0030212 6 6 0,000 9,573E-03 0,0507317 ! purine base biosynthetic process GO:0009113 14 6 0,000 9,573E-03 0,05061507 ! interaction with symbiont GO:0051702 8 6 0,000 9,573E-03 0,05049898 ! anterograde axon cargo transport GO:0008089 8 6 0,000 9,573E-03 0,05038343 ! skeletal muscle contraction GO:0003009 6 6 0,000 9,573E-03 0,0502684 ! eating behavior GO:0042755 6 6 0,000 9,573E-03 0,05015389 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 9,573E-03 0,0500399 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 9,573E-03 0,04992643 ! response to copper ion GO:0046688 9 6 0,000 9,573E-03 0,04981348 ! response to exogenous dsRNA GO:0043330 8 6 0,000 9,573E-03 0,04970103 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 9,573E-03 0,04958909 ! establishment of melanosome localization GO:0032401 9 6 0,000 9,573E-03 0,04947766 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 9,573E-03 0,04936672 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 9,573E-03 0,04925628 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 9,573E-03 0,04914633 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 9,573E-03 0,04903688 ! nucleoside catabolic process GO:0009164 6 6 0,000 9,573E-03 0,04892791 ! gas homeostasis GO:0033483 11 6 0,000 9,573E-03 0,04881942 ! hair follicle maturation GO:0048820 7 6 0,000 9,573E-03 0,04871141 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 9,573E-03 0,04860388 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 9,573E-03 0,04849682 ! Schwann cell development GO:0014044 14 6 0,000 9,573E-03 0,04839024 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 9,573E-03 0,04828412 ! dendrite morphogenesis GO:0048813 9 6 0,000 9,573E-03 0,04817846 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 9,573E-03 0,04807327 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 9,573E-03 0,04796853 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 9,573E-03 0,04786425 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 9,573E-03 0,04776043 ! histone ubiquitination GO:0016574 7 6 0,000 9,573E-03 0,04765705 ! regulation of meiosis GO:0040020 10 6 0,000 9,573E-03 0,04755412 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 9,573E-03 0,04745163 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 9,573E-03 0,04734959 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 9,573E-03 0,04724798 ! regulation of mast cell activation GO:0033003 6 6 0,000 9,573E-03 0,0471468 ! membrane to membrane docking GO:0022614 12 6 0,000 9,573E-03 0,04704606 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 9,573E-03 0,04694575 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 9,573E-03 0,04684587 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 9,573E-03 0,04674641 ! receptor internalization GO:0031623 9 6 0,000 9,573E-03 0,04664737 ! neutrophil homeostasis GO:0001780 6 6 0,000 9,573E-03 0,04654875 ! coenzyme A metabolic process GO:0015936 9 6 0,000 9,573E-03 0,04645054 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 9,573E-03 0,04635275 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 9,573E-03 0,04625537 ! protein deubiquitination GO:0016579 8 6 0,000 9,573E-03 0,0461584 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 9,573E-03 0,04606184 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 9,573E-03 0,04596567 ! peptidyl-histidine modification GO:0018202 9 6 0,000 9,573E-03 0,04586991 ! axonal fasciculation GO:0007413 9 6 0,000 9,573E-03 0,04577455 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 9,573E-03 0,04567958 ! thiamin metabolic process GO:0006772 6 6 0,000 9,573E-03 0,045585 ! midbrain development GO:0030901 6 6 0,000 9,573E-03 0,04549082 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 9,573E-03 0,04539703 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 9,573E-03 0,04530362 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 9,573E-03 0,04521059 ! progesterone metabolic process GO:0042448 8 6 0,000 9,573E-03 0,04511795 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 9,573E-03 0,04502568 ! glycolipid catabolic process GO:0019377 13 6 0,000 9,573E-03 0,04493379 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 9,573E-03 0,04484228 ! positive regulation of glucose import GO:0046326 6 6 0,000 9,573E-03 0,04475113 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 9,573E-03 0,04466036 ! adult feeding behavior GO:0008343 6 6 0,000 9,573E-03 0,04456995 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 9,573E-03 0,04447991 ! blastocyst growth GO:0001832 15 6 0,000 9,573E-03 0,04439024 ! pigment granule transport GO:0051904 12 6 0,000 9,573E-03 0,04430092 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 9,573E-03 0,04421196 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 9,573E-03 0,04412336 ! catecholamine transport GO:0051937 7 6 0,000 9,573E-03 0,04403511 ! organ or tissue specific immune response GO:0002251 7 6 0,000 9,573E-03 0,04394722 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 9,573E-03 0,04385968 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 9,573E-03 0,04377248 ! negative regulation of B cell activation GO:0050869 9 6 0,000 9,573E-03 0,04368563 ! protein prenylation GO:0018342 10 6 0,000 9,573E-03 0,04359912 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 9,573E-03 0,04351296 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 9,573E-03 0,04342713 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 9,573E-03 0,04334165 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 9,573E-03 0,0432565 ! positive regulation of coagulation GO:0050820 11 6 0,000 9,573E-03 0,04317168 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01115971 0,05022962 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01115971 0,05013151 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01115971 0,05003379 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01115971 0,04993645 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01115971 0,04983948 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01115971 0,0497429 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01115971 0,04964668 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01115971 0,04955084 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01115971 0,04945537 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01115971 0,04936026 ! reproductive behavior GO:0019098 12 7 0,000 0,01115971 0,04926552 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01115971 0,04917114 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01115971 0,04907712 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01115971 0,04898346 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01115971 0,04889016 ! oligopeptide transport GO:0006857 11 7 0,000 0,01115971 0,04879721 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01115971 0,04870462 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01115971 0,04861238 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,01115971 0,04852048 ! RNA methylation GO:0001510 11 7 0,000 0,01115971 0,04842893 ! pericardium development GO:0060039 8 7 0,000 0,01115971 0,04833773 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01115971 0,04824687 ! fibril organization GO:0043206 13 7 0,000 0,01115971 0,04815635 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01115971 0,04806617 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01115971 0,04797633 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01115971 0,04788682 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01115971 0,04779764 ! lipoprotein transport GO:0042953 9 7 0,000 0,01115971 0,0477088 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01115971 0,04762029 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01115971 0,0475321 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01115971 0,04744424 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01115971 0,04735671 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01115971 0,04726949 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01115971 0,0471826 ! chemosensory behavior GO:0007635 9 7 0,000 0,01115971 0,04709603 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01115971 0,04700977 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01115971 0,04692383 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01115971 0,0468382 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01115971 0,04675289 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01115971 0,04666788 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01115971 0,04658318 ! reflex GO:0060004 12 7 0,000 0,01115971 0,04649879 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01115971 0,04641471 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01115971 0,04633093 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01115971 0,04624745 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01115971 0,04616427 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01115971 0,04608139 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01115971 0,04599881 ! spinal cord patterning GO:0021511 7 7 0,000 0,01115971 0,04591652 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01115971 0,04583453 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01115971 0,04575282 ! adrenal gland development GO:0030325 17 7 0,000 0,01115971 0,04567141 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01115971 0,04559029 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01115971 0,04550946 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01115971 0,04542891 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01115971 0,04534865 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01115971 0,04526867 ! endosome organization GO:0007032 10 7 0,000 0,01115971 0,04518897 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01115971 0,04510955 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01115971 0,04503041 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01115971 0,04495155 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01115971 0,04487296 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01115971 0,04479465 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01115971 0,04471661 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01115971 0,04463884 ! galactose metabolic process GO:0006012 10 7 0,000 0,01115971 0,04456134 ! vesicle fusion GO:0006906 15 7 0,000 0,01115971 0,04448412 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01115971 0,04440715 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01115971 0,04433046 ! organ growth GO:0035265 11 7 0,000 0,01115971 0,04425403 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01115971 0,04417786 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01115971 0,04410195 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01115971 0,0440263 ! retinol metabolic process GO:0042572 9 7 0,000 0,01115971 0,04395092 ! behavioral fear response GO:0001662 13 7 0,000 0,01115971 0,04387579 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01115971 0,04380091 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01115971 0,04372629 ! rRNA modification GO:0000154 12 7 0,000 0,01115971 0,04365193 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01115971 0,04357782 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01115971 0,04350396 ! response to UV-B GO:0010224 11 7 0,000 0,01115971 0,04343035 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01115971 0,04335698 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01115971 0,04328387 ! intermediate filament organization GO:0045109 11 7 0,000 0,01115971 0,043211 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01115971 0,04313838 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01115971 0,043066 ! fibrinolysis GO:0042730 9 7 0,000 0,01115971 0,04299386 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01115971 0,04292196 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01115971 0,04285031 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01115971 0,04277889 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01115971 0,04270771 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01115971 0,04263677 ! response to tropane GO:0014073 13 7 0,000 0,01115971 0,04256606 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01115971 0,04249559 ! melanosome localization GO:0032400 10 7 0,000 0,01115971 0,04242535 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01115971 0,04235534 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01115971 0,04228556 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01115971 0,04221601 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01115971 0,04214669 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01115971 0,0420776 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01115971 0,04200873 ! mast cell activation GO:0045576 9 7 0,000 0,01115971 0,04194009 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01115971 0,04187167 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,01115971 0,04180348 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01115971 0,0417355 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01115971 0,04166775 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01115971 0,04160022 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01115971 0,0415329 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01115971 0,04146581 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01115971 0,04139893 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01115971 0,04133226 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01115971 0,04126581 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01115971 0,04119957 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01115971 0,04113355 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01115971 0,04106774 ! response to tumor cell GO:0002347 12 7 0,000 0,01115971 0,04100213 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01115971 0,04093674 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01115971 0,04087155 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01115971 0,04080657 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,01115971 0,0407418 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01115971 0,04067723 ! diuresis GO:0030146 12 7 0,000 0,01115971 0,04061287 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01115971 0,04054871 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01115971 0,04048475 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01115971 0,040421 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01115971 0,04035744 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01115971 0,04029409 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01115971 0,04023093 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01115971 0,04016797 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01115971 0,04010521 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01115971 0,04004264 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01115971 0,03998027 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01115971 0,03991809 ! lymph node development GO:0048535 9 7 0,000 0,01115971 0,03985611 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01115971 0,03979432 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01115971 0,03973272 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01115971 0,03967131 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01115971 0,03961008 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01115971 0,03954905 ! ATP catabolic process GO:0006200 10 7 0,000 0,01115971 0,03948821 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01115971 0,03942755 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01115971 0,03936708 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01115971 0,03930679 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01115971 0,03924669 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01115971 0,03918677 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01115971 0,03912703 ! muscle adaptation GO:0043500 12 7 0,000 0,01115971 0,03906748 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01115971 0,03900811 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01115971 0,03894891 ! retina homeostasis GO:0001895 9 7 0,000 0,01115971 0,0388899 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01115971 0,03883107 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01115971 0,03877241 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01115971 0,03871393 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01115971 0,03865562 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01115971 0,0385975 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01115971 0,03853954 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01115971 0,03848176 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01274412 0,04387945 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01274412 0,04381386 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,01274412 0,04374847 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01274412 0,04368327 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01274412 0,04361826 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01274412 0,04355345 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01274412 0,04348883 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01274412 0,0434244 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01274412 0,04336017 ! phosphate transport GO:0006817 10 8 0,000 0,01274412 0,04329612 ! N-glycan processing GO:0006491 12 8 0,000 0,01274412 0,04323226 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01274412 0,04316859 ! UTP metabolic process GO:0046051 8 8 0,000 0,01274412 0,04310511 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01274412 0,04304181 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01274412 0,0429787 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01274412 0,04291577 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01274412 0,04285303 ! succinate metabolic process GO:0006105 14 8 0,000 0,01274412 0,04279047 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01274412 0,04272809 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01274412 0,0426659 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01274412 0,04260388 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01274412 0,04254205 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01274412 0,0424804 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01274412 0,04241892 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01274412 0,04235762 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01274412 0,0422965 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01274412 0,04223555 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01274412 0,04217478 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01274412 0,04211418 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01274412 0,04205376 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01274412 0,04199351 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01274412 0,04193344 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01274412 0,04187353 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01274412 0,0418138 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01274412 0,04175423 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01274412 0,04169484 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01274412 0,04163561 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01274412 0,04157656 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01274412 0,04151767 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01274412 0,04145894 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01274412 0,04140039 ! melanin metabolic process GO:0006582 12 8 0,000 0,01274412 0,04134199 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01274412 0,04128376 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01274412 0,0412257 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01274412 0,0411678 ! macrophage activation GO:0042116 12 8 0,000 0,01274412 0,04111006 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01274412 0,04105248 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01274412 0,04099507 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01274412 0,04093781 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01274412 0,04088072 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01274412 0,04082378 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01274412 0,040767 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01274412 0,04071038 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01274412 0,04065392 ! ruffle organization GO:0031529 11 8 0,000 0,01274412 0,04059761 ! osteoblast development GO:0002076 13 8 0,000 0,01274412 0,04054146 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01274412 0,04048546 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01274412 0,04042962 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01274412 0,04037393 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01274412 0,04031839 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01274412 0,04026301 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01274412 0,04020778 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01274412 0,0401527 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01274412 0,04009777 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01274412 0,040043 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01274412 0,03998837 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01274412 0,03993389 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01274412 0,03987955 ! segment specification GO:0007379 10 8 0,000 0,01274412 0,03982537 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01274412 0,03977133 ! cellular extravasation GO:0045123 11 8 0,000 0,01274412 0,03971744 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01274412 0,0396637 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01274412 0,0396101 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01274412 0,03955664 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01274412 0,03950333 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01274412 0,03945017 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01274412 0,03939714 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01274412 0,03934426 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01274412 0,03929152 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01274412 0,03923892 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01274412 0,03918646 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01274412 0,03913414 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01274412 0,03908196 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01274412 0,03902992 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01274412 0,03897802 ! icosanoid secretion GO:0032309 12 8 0,000 0,01274412 0,03892626 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01274412 0,03887463 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01274412 0,03882314 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01274412 0,03877179 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01274412 0,03872057 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01274412 0,03866949 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01274412 0,03861854 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01274412 0,03856773 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01274412 0,03851705 ! sterol catabolic process GO:0016127 9 8 0,000 0,01274412 0,0384665 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01274412 0,03841608 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01274412 0,0383658 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01274412 0,03831565 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01274412 0,03826563 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01274412 0,03821574 ! prophase GO:0051324 11 8 0,000 0,01274412 0,03816598 ! S phase GO:0051320 8 8 0,000 0,01274412 0,03811635 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01274412 0,03806685 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01274412 0,03801747 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01274412 0,03796823 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01274412 0,03791911 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01274412 0,03787012 ! hormone catabolic process GO:0042447 13 8 0,000 0,01274412 0,03782126 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01274412 0,03777252 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01274412 0,0377239 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01274412 0,03767541 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01274412 0,03762705 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01274412 0,03757881 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01274412 0,03753069 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01274412 0,0374827 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01274412 0,03743483 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01274412 0,03738708 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01274412 0,03733946 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01274412 0,03729195 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01274412 0,03724457 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01274412 0,0371973 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01274412 0,03715016 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01274412 0,03710313 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01274412 0,03705622 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01432608 0,04160351 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01432608 0,04155105 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01432608 0,04149872 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01432608 0,04144652 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01432608 0,04139445 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01432608 0,04134251 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01432608 0,0412907 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01432608 0,04123902 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01432608 0,04118748 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01432608 0,04113606 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01432608 0,04108476 ! GTP metabolic process GO:0046039 9 9 0,000 0,01432608 0,0410336 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01432608 0,04098256 ! social behavior GO:0035176 14 9 0,000 0,01432608 0,04093165 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01432608 0,04088087 ! artery development GO:0060840 19 9 0,000 0,01432608 0,04083021 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01432608 0,04077968 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01432608 0,04072927 ! response to pain GO:0048265 16 9 0,000 0,01432608 0,04067899 ! protein complex disassembly GO:0043241 17 9 0,000 0,01432608 0,04062883 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01432608 0,04057879 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01432608 0,04052888 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01432608 0,04047909 ! lung alveolus development GO:0048286 17 9 0,000 0,01432608 0,04042942 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01432608 0,04037988 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01432608 0,04033045 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01432608 0,04028115 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01432608 0,04023197 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01432608 0,0401829 ! protein targeting to ER GO:0045047 19 9 0,000 0,01432608 0,04013396 ! T cell selection GO:0045058 18 9 0,000 0,01432608 0,04008513 ! endoderm development GO:0007492 12 9 0,000 0,01432608 0,04003643 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01432608 0,03998784 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01432608 0,03993937 ! arginine catabolic process GO:0006527 10 9 0,000 0,01432608 0,03989102 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01432608 0,03984278 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01432608 0,03979466 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01432608 0,03974666 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01432608 0,03969877 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01432608 0,039651 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01432608 0,03960334 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01432608 0,0395558 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01432608 0,03950837 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01432608 0,03946105 ! mannose metabolic process GO:0006013 9 9 0,000 0,01432608 0,03941385 ! receptor clustering GO:0043113 15 9 0,000 0,01432608 0,03936676 ! epithelial cell development GO:0002064 10 9 0,000 0,01432608 0,03931979 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01432608 0,03927292 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01432608 0,03922617 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01432608 0,03917952 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01432608 0,03913299 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01432608 0,03908657 ! motor axon guidance GO:0008045 14 9 0,000 0,01432608 0,03904026 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01432608 0,03899406 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01432608 0,03894797 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01432608 0,03890198 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01432608 0,03885611 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01432608 0,03881034 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01432608 0,03876468 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01432608 0,03871913 ! response to amine stimulus GO:0014075 13 9 0,000 0,01432608 0,03867369 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01432608 0,03862835 ! erythrocyte development GO:0048821 11 9 0,000 0,01432608 0,03858311 ! renal water homeostasis GO:0003091 14 9 0,000 0,01432608 0,03853799 ! postreplication repair GO:0006301 11 9 0,000 0,01432608 0,03849297 ! mRNA cleavage GO:0006379 13 9 0,000 0,01432608 0,03844805 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01432608 0,03840324 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01432608 0,03835853 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01432608 0,03831393 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01432608 0,03826943 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01432608 0,03822504 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01432608 0,03818074 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01432608 0,03813655 ! acid secretion GO:0046717 14 9 0,000 0,01432608 0,03809246 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01432608 0,03804848 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01432608 0,03800459 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01432608 0,03796081 ! purine base metabolic process GO:0006144 18 9 0,000 0,01432608 0,03791712 ! oocyte differentiation GO:0009994 12 9 0,000 0,01432608 0,03787354 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01432608 0,03783006 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01432608 0,03778667 ! spleen development GO:0048536 15 9 0,000 0,01432608 0,03774339 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01432608 0,03770021 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01432608 0,03765712 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01432608 0,03761413 ! detection of calcium ion GO:0005513 13 9 0,000 0,01432608 0,03757124 ! blastocyst formation GO:0001825 12 9 0,000 0,01432608 0,03752845 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01432608 0,03748576 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01432608 0,03744316 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01432608 0,03740066 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01432608 0,03735825 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01432608 0,03731595 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01432608 0,03727373 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01432608 0,03723162 ! prepulse inhibition GO:0060134 14 9 0,000 0,01432608 0,03718959 ! embryonic placenta development GO:0001892 12 9 0,000 0,01432608 0,03714767 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01432608 0,03710583 ! insulin secretion GO:0030073 17 9 0,000 0,01432608 0,03706409 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01432608 0,03702245 ! response to nicotine GO:0035094 16 9 0,000 0,01432608 0,0369809 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01432608 0,03693944 ! nucleus localization GO:0051647 15 9 0,000 0,01432608 0,03689807 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01432608 0,0368568 ! localization within membrane GO:0051668 15 9 0,000 0,01432608 0,03681562 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01590559 0,04082909 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01590559 0,04078357 ! neuron fate specification GO:0048665 11 10 0,000 0,01590559 0,04073816 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01590559 0,04069284 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01590559 0,04064763 ! thyroid gland development GO:0030878 19 10 0,000 0,01590559 0,04060251 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,01590559 0,0405575 ! synapsis GO:0007129 13 10 0,000 0,01590559 0,04051259 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01590559 0,04046777 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01590559 0,04042306 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01590559 0,04037844 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01590559 0,04033392 ! sulfate transport GO:0008272 12 10 0,000 0,01590559 0,0402895 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01590559 0,04024518 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01590559 0,04020095 ! androgen metabolic process GO:0008209 13 10 0,000 0,01590559 0,04015682 ! phospholipid efflux GO:0033700 16 10 0,000 0,01590559 0,04011279 ! hippocampus development GO:0021766 19 10 0,000 0,01590559 0,04006886 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01590559 0,04002502 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01590559 0,03998127 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01590559 0,03993763 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01590559 0,03989407 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01590559 0,03985062 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,01590559 0,03980725 ! pathogenesis GO:0009405 13 10 0,000 0,01590559 0,03976398 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01590559 0,03972081 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01590559 0,03967773 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01590559 0,03963474 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01590559 0,03959185 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01590559 0,03954904 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,01590559 0,03950633 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01590559 0,03946372 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01590559 0,03942119 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01590559 0,03937876 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01590559 0,03933641 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01590559 0,03929416 ! response to X-ray GO:0010165 16 10 0,000 0,01590559 0,039252 ! B cell proliferation GO:0042100 14 10 0,000 0,01590559 0,03920993 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01590559 0,03916795 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01590559 0,03912606 ! forebrain cell migration GO:0021885 17 10 0,000 0,01590559 0,03908426 ! lipid digestion GO:0044241 15 10 0,000 0,01590559 0,03904255 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01590559 0,03900092 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01590559 0,03895939 ! UV protection GO:0009650 14 10 0,000 0,01590559 0,03891794 ! entry into host cell GO:0030260 20 10 0,000 0,01590559 0,03887658 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01590559 0,03883531 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01590559 0,03879413 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01590559 0,03875304 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01590559 0,03871203 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01590559 0,0386711 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01590559 0,03863027 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01590559 0,03858952 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01590559 0,03854886 ! regulation of organ growth GO:0046620 11 10 0,000 0,01590559 0,03850828 ! response to dsRNA GO:0043331 18 10 0,000 0,01590559 0,03846779 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01590559 0,03842738 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01590559 0,03838706 ! embryonic axis specification GO:0000578 12 10 0,000 0,01590559 0,03834682 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01590559 0,03830667 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01590559 0,0382666 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01590559 0,03822661 ! cranial nerve development GO:0021545 12 10 0,000 0,01590559 0,03818671 ! fucose catabolic process GO:0019317 16 10 0,000 0,01590559 0,03814689 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01590559 0,03810715 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01590559 0,0380675 ! protein sumoylation GO:0016925 12 10 0,000 0,01590559 0,03802793 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01590559 0,03798844 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01590559 0,03794903 ! zymogen activation GO:0031638 14 10 0,000 0,01590559 0,0379097 ! salivary gland development GO:0007431 22 10 0,000 0,01590559 0,03787046 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01590559 0,0378313 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01590559 0,03779222 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01590559 0,03775321 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01590559 0,03771429 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,01590559 0,03767545 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01590559 0,03763669 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01590559 0,03759801 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01590559 0,03755941 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01590559 0,03752089 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01590559 0,03748244 ! detection of bacterium GO:0016045 10 10 0,000 0,01590559 0,03744408 ! embryonic gut development GO:0048566 11 10 0,000 0,01590559 0,03740579 ! activation of innate immune response GO:0002218 10 10 0,000 0,01590559 0,03736758 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,01590559 0,03732945 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01590559 0,0372914 ! developmental induction GO:0031128 13 10 0,000 0,01590559 0,03725343 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01590559 0,03721553 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01590559 0,03717771 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01590559 0,03713996 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01590559 0,0371023 ! rRNA transcription GO:0009303 17 11 0,000 0,01748267 0,04073975 ! respiratory burst GO:0045730 14 11 0,000 0,01748267 0,04069852 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01748267 0,04065737 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01748267 0,0406163 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01748267 0,04057531 ! virus-host interaction GO:0019048 17 11 0,000 0,01748267 0,04053441 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,01748267 0,04049359 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,01748267 0,04045285 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,01748267 0,0404122 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,01748267 0,04037162 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01748267 0,04033113 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,01748267 0,04029072 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,01748267 0,04025039 ! mating GO:0007618 14 11 0,000 0,01748267 0,04021014 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01748267 0,04016997 ! T cell proliferation GO:0042098 20 11 0,000 0,01748267 0,04012988 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01748267 0,04008987 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,01748267 0,04004994 ! bone resorption GO:0045453 16 11 0,000 0,01748267 0,04001009 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01748267 0,03997031 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01748267 0,03993062 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01748267 0,03989101 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01748267 0,03985147 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01748267 0,03981202 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01748267 0,03977264 ! syncytium formation GO:0006949 15 11 0,000 0,01748267 0,03973334 ! plasma membrane organization GO:0007009 18 11 0,000 0,01748267 0,03969411 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01748267 0,03965497 ! focal adhesion formation GO:0048041 24 11 0,000 0,01748267 0,0396159 ! mitotic spindle organization GO:0007052 15 11 0,000 0,01748267 0,03957691 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,01748267 0,03953799 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01748267 0,03949915 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01748267 0,03946039 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01748267 0,0394217 ! adult heart development GO:0007512 11 11 0,000 0,01748267 0,03938309 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01748267 0,03934456 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01748267 0,0393061 ! temperature homeostasis GO:0001659 16 11 0,000 0,01748267 0,03926771 ! L-glutamate transport GO:0015813 16 11 0,000 0,01748267 0,0392294 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,01748267 0,03919117 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01748267 0,03915301 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01748267 0,03911492 ! stem cell development GO:0048864 29 11 0,000 0,01748267 0,03907691 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01748267 0,03903897 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01748267 0,0390011 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,01748267 0,03896331 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01748267 0,03892559 ! vasoconstriction GO:0042310 15 11 0,000 0,01748267 0,03888795 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01748267 0,03885037 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01748267 0,03881287 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01748267 0,03877544 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,01748267 0,03873809 ! ribosome assembly GO:0042255 13 11 0,000 0,01748267 0,0387008 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01748267 0,03866359 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,01748267 0,03862645 ! chromatin silencing GO:0006342 19 11 0,000 0,01748267 0,03858938 ! nucleosome positioning GO:0016584 13 11 0,000 0,01748267 0,03855238 ! T cell homeostasis GO:0043029 20 11 0,000 0,01748267 0,03851546 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01748267 0,0384786 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,01748267 0,03844181 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01748267 0,0384051 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01748267 0,03836845 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01748267 0,03833187 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01748267 0,03829537 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01748267 0,03825893 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01748267 0,03822256 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,01748267 0,03818626 ! male genitalia development GO:0030539 13 11 0,000 0,01748267 0,03815003 ! cholesterol efflux GO:0033344 19 11 0,000 0,01748267 0,03811387 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,01748267 0,03807778 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,01748267 0,03804176 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01748267 0,0380058 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01748267 0,03796991 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01748267 0,03793409 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01748267 0,03789834 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01748267 0,03786265 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01748267 0,03782703 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01748267 0,03779148 ! lysogeny GO:0030069 18 11 0,000 0,01748267 0,037756 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,01748267 0,03772058 ! acrosome reaction GO:0007340 13 11 0,000 0,01748267 0,03768523 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01748267 0,03764994 ! lactation GO:0007595 20 12 0,000 0,01905731 0,04100262 ! reproductive cellular process GO:0048610 14 12 0,000 0,01905731 0,0409643 ! tRNA modification GO:0006400 14 12 0,000 0,01905731 0,04092605 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,01905731 0,04088787 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,01905731 0,04084977 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,01905731 0,04081173 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,01905731 0,04077377 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,01905731 0,04073588 ! non-recombinational repair GO:0000726 19 12 0,000 0,01905731 0,04069805 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,01905731 0,0406603 ! peroxisomal transport GO:0043574 21 12 0,000 0,01905731 0,04062262 ! cartilage condensation GO:0001502 18 12 0,000 0,01905731 0,040585 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,01905731 0,04054746 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,01905731 0,04050998 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01905731 0,04047258 ! heart looping GO:0001947 15 12 0,000 0,01905731 0,04043524 ! palate development GO:0060021 15 12 0,000 0,01905731 0,04039797 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,01905731 0,04036078 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,01905731 0,04032364 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01905731 0,04028658 ! arginine metabolic process GO:0006525 13 12 0,000 0,01905731 0,04024959 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,01905731 0,04021266 ! methionine metabolic process GO:0006555 13 12 0,000 0,01905731 0,0401758 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,01905731 0,04013901 ! Golgi organization GO:0007030 18 12 0,000 0,01905731 0,04010229 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,01905731 0,04006563 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,01905731 0,04002904 ! monoamine transport GO:0015844 13 12 0,000 0,01905731 0,03999252 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01905731 0,03995606 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,01905731 0,03991967 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,01905731 0,03988335 ! L-amino acid transport GO:0015807 20 12 0,000 0,01905731 0,03984709 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,01905731 0,0398109 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01905731 0,03977477 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,01905731 0,03973871 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01905731 0,03970272 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,01905731 0,03966679 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,01905731 0,03963092 ! cerebellum development GO:0021549 13 12 0,000 0,01905731 0,03959512 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01905731 0,03955939 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01905731 0,03952372 ! histone acetylation GO:0016573 23 12 0,000 0,01905731 0,03948811 ! histone methylation GO:0016571 15 12 0,000 0,01905731 0,03945257 ! autonomic nervous system development GO:0048483 23 12 0,000 0,01905731 0,03941709 ! gland morphogenesis GO:0022612 23 12 0,000 0,01905731 0,03938167 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,01905731 0,03934632 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,01905731 0,03931103 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,01905731 0,03927581 ! response to gamma radiation GO:0010332 20 12 0,000 0,01905731 0,03924065 ! regulation of epidermis development GO:0045682 17 12 0,000 0,01905731 0,03920555 ! intestinal absorption GO:0050892 19 12 0,000 0,01905731 0,03917051 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,01905731 0,03913554 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01905731 0,03910063 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,01905731 0,03906578 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,01905731 0,03903099 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,01905731 0,03899626 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01905731 0,0389616 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,01905731 0,038927 ! microspike assembly GO:0030035 23 12 0,000 0,01905731 0,03889246 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,01905731 0,03885798 ! response to cold GO:0009409 14 12 0,000 0,01905731 0,03882356 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,02062951 0,04198927 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,02062951 0,04195214 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02062951 0,04191508 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02062951 0,04187808 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,02062951 0,04184115 ! water transport GO:0006833 17 13 0,000 0,02062951 0,04180429 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02062951 0,04176749 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02062951 0,04173076 ! lipid localization GO:0010876 24 13 0,000 0,02062951 0,04169409 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02062951 0,04165748 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02062951 0,04162094 ! organelle fusion GO:0048284 28 13 0,000 0,02062951 0,04158446 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02062951 0,04154805 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02062951 0,0415117 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,02062951 0,04147541 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02062951 0,04143919 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02062951 0,04140303 ! response to hexose stimulus GO:0009746 19 13 0,000 0,02062951 0,04136693 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,02062951 0,0413309 ! glutamate metabolic process GO:0006536 18 13 0,000 0,02062951 0,04129493 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02062951 0,04125902 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02062951 0,04122317 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02062951 0,04118739 ! NAD metabolic process GO:0019674 21 13 0,000 0,02062951 0,04115167 ! exocrine system development GO:0035272 27 13 0,000 0,02062951 0,041116 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02062951 0,04108041 ! bone mineralization GO:0030282 15 13 0,000 0,02062951 0,04104487 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02062951 0,04100939 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02062951 0,04097398 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02062951 0,04093863 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02062951 0,04090334 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,02062951 0,0408681 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02062951 0,04083293 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,02062951 0,04079782 ! genitalia development GO:0048806 15 13 0,000 0,02062951 0,04076277 ! regulation of cellular pH GO:0030641 20 13 0,000 0,02062951 0,04072779 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,02062951 0,04069286 ! cellular pigmentation GO:0033059 24 13 0,000 0,02062951 0,04065799 ! tissue regeneration GO:0042246 21 13 0,000 0,02062951 0,04062318 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02062951 0,04058843 ! cofactor transport GO:0051181 19 13 0,000 0,02062951 0,04055373 ! NADP metabolic process GO:0006739 18 13 0,000 0,02062951 0,0405191 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02062951 0,04048453 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02062951 0,04045002 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02062951 0,04041556 ! gas transport GO:0015669 18 13 0,000 0,02062951 0,04038117 ! regulation of RNA stability GO:0043487 28 13 0,000 0,02062951 0,04034683 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02062951 0,04031255 ! regulation of axon extension GO:0030516 23 13 0,000 0,02062951 0,04027833 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,02062951 0,04024416 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02062951 0,04021006 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02062951 0,04017601 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02062951 0,04014202 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02062951 0,04010809 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02062951 0,04007421 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,02219928 0,04308721 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,02219928 0,04305088 ! superoxide anion generation GO:0042554 18 14 0,000 0,02219928 0,04301462 ! neuron maturation GO:0042551 21 14 0,000 0,02219928 0,04297841 ! regulation of S phase GO:0033261 18 14 0,000 0,02219928 0,04294226 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,02219928 0,04290618 ! myotube differentiation GO:0014902 21 14 0,000 0,02219928 0,04287015 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,02219928 0,04283419 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,02219928 0,04279828 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,02219928 0,04276244 ! inositol metabolic process GO:0006020 20 14 0,000 0,02219928 0,04272665 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,02219928 0,04269093 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,02219928 0,04265526 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,02219928 0,04261966 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,02219928 0,04258411 ! gene silencing by RNA GO:0031047 20 14 0,000 0,02219928 0,04254862 ! response to cAMP GO:0051591 19 14 0,000 0,02219928 0,0425132 ! limbic system development GO:0021761 25 14 0,000 0,02219928 0,04247783 ! startle response GO:0001964 21 14 0,000 0,02219928 0,04244252 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,02219928 0,04240727 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,02219928 0,04237207 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,02219928 0,04233694 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,02219928 0,04230186 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,02219928 0,04226685 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,02219928 0,04223188 ! glycine metabolic process GO:0006544 22 14 0,000 0,02219928 0,04219698 ! pituitary gland development GO:0021983 23 14 0,000 0,02219928 0,04216214 ! cellular response to starvation GO:0009267 21 14 0,000 0,02219928 0,04212735 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,02219928 0,04209262 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,02219928 0,04205795 ! regulation of heart rate GO:0002027 23 14 0,000 0,02219928 0,04202333 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,02219928 0,04198877 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,02219928 0,04195427 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,02219928 0,04191983 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,02219928 0,04188544 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,02219928 0,04185111 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,02219928 0,04181683 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,02219928 0,04178261 ! axon cargo transport GO:0008088 27 14 0,000 0,02219928 0,04174845 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,02219928 0,04171434 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,02219928 0,04168028 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,02219928 0,04164629 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,02219928 0,04161235 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02219928 0,04157846 ! mRNA splice site selection GO:0006376 26 14 0,000 0,02219928 0,04154463 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,02219928 0,04151085 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,02219928 0,04147713 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,02219928 0,04144347 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,02219928 0,04140985 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,02219928 0,0413763 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,02219928 0,04134279 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,02219928 0,04130934 ! muscle maintenance GO:0046716 19 14 0,000 0,02219928 0,04127595 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,02219928 0,04124261 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,02219928 0,04120932 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,02219928 0,04117609 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,02219928 0,04114291 ! cell killing GO:0001906 20 14 0,000 0,02219928 0,04110978 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,02219928 0,04107671 ! cilium assembly GO:0042384 20 14 0,000 0,02219928 0,04104369 ! peptide hormone secretion GO:0030072 23 14 0,000 0,02219928 0,04101072 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,02376663 0,04387099 ! metencephalon development GO:0022037 19 15 0,000 0,02376663 0,0438358 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02376663 0,04380068 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,02376663 0,04376561 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,02376663 0,0437306 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,02376663 0,04369564 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,02376663 0,04366074 ! lipid phosphorylation GO:0046834 23 15 0,000 0,02376663 0,0436259 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,02376663 0,04359111 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,02376663 0,04355637 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,02376663 0,04352169 ! bile acid metabolic process GO:0008206 22 15 0,000 0,02376663 0,04348707 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,02376663 0,0434525 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,02376663 0,04341799 ! adult walking behavior GO:0007628 25 15 0,000 0,02376663 0,04338353 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02376663 0,04334913 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,02376663 0,04331478 ! myoblast differentiation GO:0045445 27 15 0,000 0,02376663 0,04328048 ! centrosome cycle GO:0007098 16 15 0,000 0,02376663 0,04324624 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,02376663 0,04321205 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,02376663 0,04317792 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,02376663 0,04314384 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,02376663 0,04310982 ! cerebral cortex development GO:0021987 29 15 0,000 0,02376663 0,04307585 ! response to osmotic stress GO:0006970 22 15 0,000 0,02376663 0,04304193 ! vesicle coating GO:0006901 25 15 0,000 0,02376663 0,04300806 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,02376663 0,04297425 ! DNA integration GO:0015074 22 15 0,000 0,02376663 0,04294049 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,02376663 0,04290679 ! peptide secretion GO:0002790 27 15 0,000 0,02376663 0,04287314 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,02376663 0,04283954 ! regulation of vasodilation GO:0042312 24 15 0,000 0,02376663 0,04280599 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,02376663 0,04277249 ! neuron recognition GO:0008038 22 15 0,000 0,02376663 0,04273905 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,02376663 0,04270566 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,02376663 0,04267232 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,02376663 0,04263904 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,02376663 0,0426058 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,02376663 0,04257262 ! biomineral formation GO:0031214 18 15 0,000 0,02376663 0,04253949 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,02376663 0,04250641 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,02376663 0,04247339 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,02376663 0,04244041 ! dopamine metabolic process GO:0042417 30 15 0,000 0,02376663 0,04240748 ! organic cation transport GO:0015695 19 15 0,000 0,02376663 0,04237461 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,02376663 0,04234179 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,02376663 0,04230901 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,02376663 0,04227629 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,02376663 0,04224362 ! defense response to virus GO:0051607 27 15 0,000 0,02376663 0,042211 ! peptide hormone processing GO:0016486 19 15 0,000 0,02376663 0,04217843 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,02376663 0,04214591 ! protein secretion GO:0009306 27 16 0,000 0,02533155 0,04488642 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,02533155 0,04485187 ! hormone secretion GO:0046879 25 16 0,000 0,02533155 0,04481736 ! bone remodeling GO:0046849 24 16 0,000 0,02533155 0,04478292 ! endothelial cell migration GO:0043542 22 16 0,000 0,02533155 0,04474852 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,02533155 0,04471418 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,02533155 0,04467989 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02533155 0,04464565 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,02533155 0,04461147 ! glial cell development GO:0021782 24 16 0,000 0,02533155 0,04457733 ! patterning of blood vessels GO:0001569 24 16 0,000 0,02533155 0,04454325 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,02533155 0,04450922 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,02533155 0,04447525 ! protein polyubiquitination GO:0000209 26 16 0,000 0,02533155 0,04444132 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,02533155 0,04440745 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,02533155 0,04437363 ! fructose metabolic process GO:0006000 20 16 0,000 0,02533155 0,04433986 ! regulation of protein binding GO:0043393 27 16 0,000 0,02533155 0,04430614 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,02533155 0,04427247 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,02533155 0,04423886 ! protein export from nucleus GO:0006611 24 16 0,000 0,02533155 0,04420529 ! negative regulation of immune response GO:0050777 28 16 0,000 0,02533155 0,04417178 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,02533155 0,04413831 ! DNA replication initiation GO:0006270 25 16 0,000 0,02533155 0,0441049 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,02533155 0,04407154 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,02533155 0,04403823 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,02533155 0,04400496 ! diencephalon development GO:0021536 25 16 0,000 0,02533155 0,04397175 ! oogenesis GO:0048477 23 16 0,000 0,02533155 0,04393859 ! neural crest cell migration GO:0001755 24 16 0,000 0,02533155 0,04390548 ! G1 phase GO:0051318 27 16 0,000 0,02533155 0,04387242 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,02533155 0,04383941 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02533155 0,04380645 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,02533155 0,04377353 ! steroid catabolic process GO:0006706 22 16 0,000 0,02533155 0,04374067 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02533155 0,04370786 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,02533155 0,04367509 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,02533155 0,04364238 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,02533155 0,04360971 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,02533155 0,04357709 ! sperm-egg recognition GO:0035036 16 16 0,000 0,02533155 0,04354452 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,02533155 0,043512 ! nerve development GO:0021675 18 16 0,000 0,02533155 0,04347953 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,02533155 0,04344711 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,02533155 0,04341473 ! negative regulation of translation GO:0017148 22 16 0,000 0,02533155 0,04338241 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,02689406 0,04602406 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,02689406 0,04598984 ! negative regulation of defense response GO:0031348 19 17 0,000 0,02689406 0,04595567 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,02689406 0,04592156 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,02689406 0,04588749 ! glycerol metabolic process GO:0006071 20 17 0,000 0,02689406 0,04585347 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,02689406 0,04581951 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,02689406 0,04578559 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02689406 0,04575173 ! signal complex assembly GO:0007172 29 17 0,000 0,02689406 0,04571791 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,02689406 0,04568415 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,02689406 0,04565043 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,02689406 0,04561677 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,02689406 0,04558315 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,02689406 0,04554958 ! memory GO:0007613 25 17 0,000 0,02689406 0,04551607 ! keratinization GO:0031424 17 17 0,000 0,02689406 0,0454826 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,02689406 0,04544918 ! retinoid metabolic process GO:0001523 22 17 0,000 0,02689406 0,04541581 GO:0016101|diterpenoid metabolic process, ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,02689406 0,04538249 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,02689406 0,04534922 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,02689406 0,045316 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,02689406 0,04528282 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,02689406 0,0452497 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,02689406 0,04521662 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,02689406 0,04518359 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,02689406 0,04515061 ! membrane budding GO:0006900 29 17 0,000 0,02689406 0,04511768 ! heme metabolic process GO:0042168 27 17 0,000 0,02689406 0,04508479 ! actin filament bundle formation GO:0051017 26 17 0,000 0,02689406 0,04505196 ! neuromuscular junction development GO:0007528 23 17 0,000 0,02689406 0,04501917 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,02689406 0,04498643 ! body fluid secretion GO:0007589 27 17 0,000 0,02689406 0,04495373 ! stem cell differentiation GO:0048863 36 17 0,000 0,02689406 0,04492109 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02689406 0,04488849 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,02689406 0,04485594 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,02689406 0,04482343 ! sensory perception of pain GO:0019233 23 17 0,000 0,02689406 0,04479097 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,02689406 0,04475856 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,02689406 0,0447262 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,02689406 0,04469388 ! synaptogenesis GO:0007416 24 17 0,000 0,02689406 0,04466161 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,02689406 0,04462939 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02689406 0,04459721 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,02689406 0,04456508 ! cell-cell junction organization GO:0045216 25 17 0,000 0,02689406 0,044533 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,02689406 0,04450096 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,02689406 0,04446897 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,02689406 0,04443702 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,02689406 0,04440512 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,02689406 0,04437327 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,02689406 0,04434146 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,02845415 0,04688004 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,02845415 0,04684649 ! positive regulation of translation GO:0045727 28 18 0,000 0,02845415 0,04681298 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,02845415 0,04677952 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,02845415 0,0467461 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02845415 0,04671274 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,02845415 0,04667942 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02845415 0,04664615 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,02845415 0,04661292 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,02845415 0,04657975 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,02845415 0,04654662 ! axis specification GO:0009798 26 18 0,000 0,02845415 0,04651353 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,02845415 0,0464805 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,02845415 0,04644751 ! pancreas development GO:0031016 26 18 0,000 0,02845415 0,04641457 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,02845415 0,04638167 ! glutamine metabolic process GO:0006541 23 18 0,000 0,02845415 0,04634883 ! response to retinoic acid GO:0032526 25 18 0,000 0,02845415 0,04631602 ! pigmentation during development GO:0048066 31 18 0,000 0,02845415 0,04628327 ! central nervous system neuron development GO:0021954 30 18 0,000 0,02845415 0,04625056 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,02845415 0,0462179 ! fucose metabolic process GO:0006004 26 18 0,000 0,02845415 0,04618528 ! response to fungus GO:0009620 19 18 0,000 0,02845415 0,04615271 ! peptide cross-linking GO:0018149 31 18 0,000 0,02845415 0,04612018 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,02845415 0,04608771 ! heart process GO:0003015 27 18 0,000 0,02845415 0,04605527 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,02845415 0,04602288 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,02845415 0,04599054 ! visual learning GO:0008542 35 18 0,000 0,02845415 0,04595825 ! somitogenesis GO:0001756 24 18 0,000 0,02845415 0,04592599 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,02845415 0,04589379 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,02845415 0,04586163 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,02845415 0,04582951 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,02845415 0,04579744 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,02845415 0,04576541 ! vitamin transport GO:0051180 24 18 0,000 0,02845415 0,04573343 ! hormone transport GO:0009914 27 18 0,000 0,02845415 0,0457015 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,02845415 0,0456696 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,02845415 0,04563776 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02845415 0,04560595 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,02845415 0,04557419 ! cell-cell recognition GO:0009988 20 18 0,000 0,02845415 0,04554248 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,02845415 0,04551081 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,02845415 0,04547918 ! regulation of glucose import GO:0046324 21 18 0,000 0,02845415 0,0454476 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,02845415 0,04541606 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,02845415 0,04538456 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,02845415 0,04535311 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,02845415 0,0453217 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,03001183 0,04776969 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,03001183 0,04773665 ! positive regulation of ossification GO:0045778 30 19 0,000 0,03001183 0,04770366 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,03001183 0,04767072 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,03001183 0,04763782 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,03001183 0,04760497 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,03001183 0,04757216 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,03001183 0,04753939 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,03001183 0,04750668 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,03001183 0,047474 ! regeneration GO:0031099 32 19 0,000 0,03001183 0,04744137 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,03001183 0,04740879 ! response to alkaloid GO:0043279 32 19 0,000 0,03001183 0,04737625 ! sensory perception of taste GO:0050909 23 19 0,000 0,03001183 0,04734376 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,03001183 0,04731131 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,03001183 0,0472789 ! smooth muscle contraction GO:0006939 36 19 0,000 0,03001183 0,04724654 ! peroxisome organization GO:0007031 29 19 0,000 0,03001183 0,04721423 ! digestive system process GO:0022600 30 19 0,000 0,03001183 0,04718196 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,03001183 0,04714973 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,03001183 0,04711754 ! response to vitamin A GO:0033189 26 19 0,000 0,03001183 0,0470854 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,03001183 0,04705331 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,03001183 0,04702125 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,03001183 0,04698924 ! response to starvation GO:0042594 30 19 0,000 0,03001183 0,04695728 ! sex determination GO:0007530 29 19 0,000 0,03001183 0,04692536 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,03001183 0,04689348 ! plasma membrane fusion GO:0045026 23 19 0,000 0,03001183 0,04686164 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,03001183 0,04682985 ! cytolysis GO:0019835 20 19 0,000 0,03001183 0,0467981 ! renal system process GO:0003014 35 19 0,000 0,03001183 0,0467664 ! vasodilation GO:0042311 33 19 0,000 0,03001183 0,04673473 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,03001183 0,04670311 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,03001183 0,04667154 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,03001183 0,04664 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,03001183 0,04660851 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,03001183 0,04657706 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,03001183 0,04654565 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,03001183 0,04651429 ! sarcomere organization GO:0045214 23 19 0,000 0,03001183 0,04648296 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,03001183 0,04645168 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,03001183 0,04642044 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,03001183 0,04638925 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,03001183 0,04635809 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,03001183 0,04632698 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,03001183 0,04629591 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,03001183 0,04626488 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,03001183 0,04623389 ! protein stabilization GO:0050821 26 19 0,000 0,03001183 0,04620295 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,0315671 0,04856476 ! iron ion transport GO:0006826 37 20 0,000 0,0315671 0,0485323 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,0315671 0,04849988 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,0315671 0,0484675 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,0315671 0,04843517 ! response to vitamin GO:0033273 29 20 0,000 0,0315671 0,04840288 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,0315671 0,04837063 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,0315671 0,04833843 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,0315671 0,04830627 ! spinal cord development GO:0021510 31 20 0,000 0,0315671 0,04827415 ! response to ethanol GO:0045471 37 20 0,000 0,0315671 0,04824207 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,0315671 0,04821004 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,0315671 0,04817805 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,0315671 0,0481461 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,0315671 0,04811419 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,0315671 0,04808233 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,0315671 0,04805051 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,0315671 0,04801873 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,0315671 0,04798699 ! pallium development GO:0021543 38 20 0,000 0,0315671 0,0479553 ! DNA modification GO:0006304 28 20 0,000 0,0315671 0,04792364 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,0315671 0,04789203 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,0315671 0,04786046 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,0315671 0,04782893 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,0315671 0,04779745 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,0315671 0,047766 ! collagen catabolic process GO:0030574 25 20 0,000 0,0315671 0,0477346 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,0315671 0,04770323 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,0315671 0,04767191 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,0315671 0,04764063 ! alditol metabolic process GO:0019400 24 20 0,000 0,0315671 0,04760939 ! actin filament-based movement GO:0030048 34 20 0,000 0,0315671 0,04757819 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,03311996 0,04988599 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,03311996 0,04985334 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,03311996 0,04982074 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,03311996 0,04978818 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,03311996 0,04975566 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,03311996 0,04972318 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,03311996 0,04969074 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,03311996 0,04965835 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,03311996 0,049626 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,03311996 0,04959369 ! protein amino acid acylation GO:0043543 37 21 0,000 0,03311996 0,04956142 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,03311996 0,0495292 ! vesicle docking GO:0048278 27 21 0,000 0,03311996 0,04949702 ! phototransduction GO:0007602 25 21 0,000 0,03311996 0,04946488 ! dendrite development GO:0016358 35 21 0,000 0,03311996 0,04943278 ! visual behavior GO:0007632 39 21 0,000 0,03311996 0,04940072 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,03311996 0,0493687 ! ovarian follicle development GO:0001541 30 21 0,000 0,03311996 0,04933673 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,03311996 0,0493048 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,03311996 0,0492729 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,03311996 0,04924105 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,03311996 0,04920924 ! cell aging GO:0007569 32 21 0,000 0,03311996 0,04917747 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,03311996 0,04914575 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,03311996 0,04911406 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,03311996 0,04908242 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,03311996 0,04905081 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,03311996 0,04901925 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,03311996 0,04898772 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,03311996 0,04895624 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,03311996 0,0489248 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,03311996 0,04889339 ! fatty acid transport GO:0015908 30 21 0,000 0,03311996 0,04886203 ! immunoglobulin production GO:0002377 33 21 0,000 0,03311996 0,04883071 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,03311996 0,04879943 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,03311996 0,04876819 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,03311996 0,04873699 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,03311996 0,04870582 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,03311996 0,0486747 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,03311996 0,04864362 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,03311996 0,04861258 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,03311996 0,04858157 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,03311996 0,04855061 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,03311996 0,04851969 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,03311996 0,0484888 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,03311996 0,04845796 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,03311996 0,04842715 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,03467042 0,05066199 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,03467042 0,05062983 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,03467042 0,0505977 ! viral genome replication GO:0019079 29 22 0,000 0,03467042 0,05056561 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,03467042 0,05053357 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,03467042 0,05050157 ! leukocyte adhesion GO:0007159 38 22 0,000 0,03467042 0,0504696 ! molting cycle process GO:0022404 40 22 0,000 0,03467042 0,05043768 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,03467042 0,0504058 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,03467042 0,05037396 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,03467042 0,05034216 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,03467042 0,05031039 ! vasculogenesis GO:0001570 33 22 0,000 0,03467042 0,05027867 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,03467042 0,05024699 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,03467042 0,05021535 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,03467042 0,05018375 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,03467042 0,05015219 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,03467042 0,05012066 ! lysosome organization GO:0007040 37 22 0,000 0,03467042 0,05008918 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,03467042 0,05005774 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,03467042 0,05002633 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,03467042 0,04999497 ! regulation of behavior GO:0050795 38 22 0,000 0,03467042 0,04996364 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,03467042 0,04993236 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,03467042 0,04990111 ! membrane depolarization GO:0051899 35 22 0,000 0,03467042 0,0498699 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,03467042 0,04983873 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,03467042 0,0498076 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,03467042 0,04977651 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,03467042 0,04974546 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,03467042 0,04971445 ! blastocyst development GO:0001824 37 22 0,000 0,03467042 0,04968347 ! neural tube closure GO:0001843 33 22 0,000 0,03467042 0,04965254 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,03467042 0,04962164 ! protein tetramerization GO:0051262 39 22 0,000 0,03467042 0,04959078 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,03621849 0,05177286 ! neuron fate commitment GO:0048663 32 23 0,000 0,03621849 0,0517407 ! embryonic pattern specification GO:0009880 31 23 0,000 0,03621849 0,05170858 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,03621849 0,0516765 ! myelination GO:0042552 35 23 0,000 0,03621849 0,05164447 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,03621849 0,05161247 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,03621849 0,05158051 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,03621849 0,05154859 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,03621849 0,05151671 ! vesicle targeting GO:0006903 32 23 0,000 0,03621849 0,05148487 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,03621849 0,05145307 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,03621849 0,05142131 ! osteoblast differentiation GO:0001649 40 23 0,000 0,03621849 0,05138959 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,03621849 0,05135791 ! interaction with host GO:0051701 37 23 0,000 0,03621849 0,05132626 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,03621849 0,05129466 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,03621849 0,05126309 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,03621849 0,05123157 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,03621849 0,05120008 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,03621849 0,05116863 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,03621849 0,05113722 ! cell fate determination GO:0001709 45 23 0,000 0,03621849 0,05110584 ! pentose metabolic process GO:0019321 31 23 0,000 0,03621849 0,05107451 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,03621849 0,05104321 ! spermatid development GO:0007286 33 23 0,000 0,03621849 0,05101196 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,03621849 0,05098074 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,03621849 0,05094956 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,03621849 0,05091841 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,03621849 0,05088731 ! telomere organization GO:0032200 32 23 0,000 0,03621849 0,05085624 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,03621849 0,05082521 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,03621849 0,05079422 ! regulation of amine transport GO:0051952 38 23 0,000 0,03621849 0,05076327 ! liver development GO:0001889 40 23 0,000 0,03621849 0,05073235 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,03776416 0,05286523 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,03776416 0,05283307 ! initiation of viral infection GO:0019059 42 24 0,000 0,03776416 0,05280095 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,03776416 0,05276888 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,03776416 0,05273684 ! superoxide metabolic process GO:0006801 32 24 0,000 0,03776416 0,05270484 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,03776416 0,05267287 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,03776416 0,05264095 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,03776416 0,05260907 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,03776416 0,05257722 ! sperm motility GO:0030317 27 24 0,000 0,03776416 0,05254541 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,03776416 0,05251365 ! vacuole organization GO:0007033 39 24 0,000 0,03776416 0,05248192 ! receptor metabolic process GO:0043112 37 24 0,000 0,03776416 0,05245022 ! neural crest cell development GO:0014032 39 24 0,000 0,03776416 0,05241857 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,03776416 0,05238695 ! primary neural tube formation GO:0014020 35 24 0,000 0,03776416 0,05235538 ! negative regulation of cell development GO:0010721 56 24 0,000 0,03776416 0,05232384 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,03776416 0,05229234 ! base-excision repair GO:0006284 31 24 0,000 0,03776416 0,05226087 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,03776416 0,05222945 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,03776416 0,05219806 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,03776416 0,05216671 ! glutathione metabolic process GO:0006749 29 24 0,000 0,03776416 0,0521354 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,03776416 0,05210412 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,03776416 0,05207288 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,03776416 0,05204168 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,03930744 0,054136 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,03930744 0,0541036 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,03930744 0,05407124 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,03930744 0,05403892 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,03930744 0,05400664 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,03930744 0,0539744 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,03930744 0,05394219 ! peptide transport GO:0015833 43 25 0,000 0,03930744 0,05391003 ! male gonad development GO:0008584 33 25 0,000 0,03930744 0,0538779 ! iron ion homeostasis GO:0055072 39 25 0,000 0,03930744 0,05384581 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,03930744 0,05381376 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,03930744 0,05378175 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,03930744 0,05374977 ! phospholipid transport GO:0015914 35 25 0,000 0,03930744 0,05371784 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,03930744 0,05368594 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,03930744 0,05365408 ! detection of light stimulus GO:0009583 30 25 0,000 0,03930744 0,05362225 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,03930744 0,05359047 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,03930744 0,05355872 ! leukocyte proliferation GO:0070661 39 25 0,000 0,03930744 0,05352701 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,03930744 0,05349534 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,04084834 0,05555954 ! translational initiation GO:0006413 43 26 0,000 0,04084834 0,0555267 ! regulation of pH GO:0006885 36 26 0,000 0,04084834 0,0554939 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,04084834 0,05546114 ! circadian rhythm GO:0007623 42 26 0,000 0,04084834 0,05542842 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,04084834 0,05539574 ! post-embryonic development GO:0009791 42 26 0,000 0,04084834 0,0553631 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,04084834 0,05533049 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,04084834 0,05529792 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,04084834 0,0552654 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,04084834 0,05523291 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,04084834 0,05520045 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,04084834 0,05516804 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,04084834 0,05513567 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,04084834 0,05510333 ! regulation of coagulation GO:0050818 39 26 0,000 0,04084834 0,05507103 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,04238685 0,05711175 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,04238685 0,05707831 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,04238685 0,05704491 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,04238685 0,05701155 ! membrane docking GO:0022406 39 27 0,000 0,04238685 0,05697823 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,04238685 0,05694495 ! catechol metabolic process GO:0009712 43 27 0,000 0,04238685 0,0569117 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,04238685 0,0568785 ! acute-phase response GO:0006953 42 27 0,000 0,04238685 0,05684533 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,04238685 0,05681221 ! myofibril assembly GO:0030239 36 27 0,000 0,04238685 0,05677912 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,04238685 0,05674607 ! response to ionizing radiation GO:0010212 47 27 0,000 0,04238685 0,05671306 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,04238685 0,05668009 ! natural killer cell activation GO:0030101 35 27 0,000 0,04238685 0,05664715 ! lipid oxidation GO:0034440 38 27 0,000 0,04238685 0,05661426 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,04238685 0,0565814 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,04238685 0,05654858 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,04238685 0,0565158 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,04238685 0,05648305 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,04238685 0,05645035 ! gene silencing GO:0016458 41 27 0,000 0,04238685 0,05641768 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,04392298 0,05842849 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,04392298 0,05839471 ! phenol metabolic process GO:0018958 44 28 0,000 0,04392298 0,05836098 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,04392298 0,05832728 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,04392298 0,05829362 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,04392298 0,05826001 ! cell junction assembly GO:0034329 56 28 0,000 0,04392298 0,05822643 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,04392298 0,05819289 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,04392298 0,05815938 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,04392298 0,05812592 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,04392298 0,0580925 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,04392298 0,05805911 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,04392298 0,05802576 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,04392298 0,05799245 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,04392298 0,05795918 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,04392298 0,05792595 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,04392298 0,05789275 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,04392298 0,05785959 ! mesoderm formation GO:0001707 46 28 0,000 0,04392298 0,05782647 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,04392298 0,05779339 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,04392298 0,05776035 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,04392298 0,05772734 ! ensheathment of neurons GO:0007272 43 28 0,000 0,04392298 0,05769438 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,04392298 0,05766144 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,04392298 0,05762855 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,04392298 0,0575957 ! neural tube formation GO:0001841 41 28 0,000 0,04392298 0,05756288 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,04392298 0,0575301 ! placenta development GO:0001890 37 28 0,000 0,04392298 0,05749735 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,04545673 0,05947127 ! regulation of innate immune response GO:0045088 38 29 0,000 0,04545673 0,05943746 ! ovulation cycle process GO:0022602 41 29 0,000 0,04545673 0,05940369 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,04545673 0,05936995 ! protein targeting to membrane GO:0006612 53 29 0,000 0,04545673 0,05933626 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,04545673 0,0593026 ! mismatch repair GO:0006298 34 29 0,000 0,04545673 0,05926898 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,04545673 0,0592354 ! muscle cell development GO:0055001 38 29 0,000 0,04545673 0,05920186 ! formation of primary germ layer GO:0001704 48 29 0,000 0,04545673 0,05916836 ! telencephalon development GO:0021537 52 29 0,000 0,04545673 0,05913489 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,04545673 0,05910146 ! eye morphogenesis GO:0048592 51 29 0,000 0,04545673 0,05906807 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,04545673 0,05903472 ! tissue homeostasis GO:0001894 42 29 0,000 0,04545673 0,0590014 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,04698812 0,06095469 ! collagen metabolic process GO:0032963 40 30 0,000 0,04698812 0,06092033 ! organic anion transport GO:0015711 51 30 0,000 0,04698812 0,06088601 ! cholesterol transport GO:0030301 46 30 0,000 0,04698812 0,06085173 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,04698812 0,06081748 ! spliceosome assembly GO:0000245 49 30 0,000 0,04698812 0,06078328 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,04698812 0,06074911 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,04698812 0,06071498 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,04698812 0,06068089 ! ceramide metabolic process GO:0006672 43 30 0,000 0,04698812 0,06064684 ! ovulation cycle GO:0042698 43 30 0,000 0,04698812 0,06061282 ! hindbrain development GO:0030902 45 30 0,000 0,04698812 0,06057885 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,04698812 0,06054491 ! adult locomotory behavior GO:0008344 47 30 0,000 0,04698812 0,06051101 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,04698812 0,06047715 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,04698812 0,06044333 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,04698812 0,06040954 ! response to heat GO:0009408 41 30 0,000 0,04698812 0,06037579 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,04698812 0,06034208 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,04698812 0,06030841 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,04851713 0,06223614 ! negative regulation of secretion GO:0051048 49 31 0,000 0,04851713 0,06220145 ! mammary gland development GO:0030879 57 31 0,000 0,04851713 0,06216679 ! glial cell differentiation GO:0010001 55 31 0,000 0,04851713 0,06213218 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,04851713 0,0620976 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,04851713 0,06206307 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,04851713 0,06202857 ! odontogenesis GO:0042476 50 31 0,000 0,04851713 0,06199411 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,04851713 0,06195969 ! segmentation GO:0035282 41 31 0,000 0,04851713 0,0619253 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,04851713 0,06189096 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,04851713 0,06185665 ! metanephros development GO:0001656 58 31 0,000 0,04851713 0,06182238 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,04851713 0,06178815 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,04851713 0,06175395 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,04851713 0,0617198 ! cell fate specification GO:0001708 37 31 0,000 0,04851713 0,06168568 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,04851713 0,0616516 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,04851713 0,06161756 ! RNA modification GO:0009451 40 31 0,000 0,04851713 0,06158355 ! regulation of muscle development GO:0048634 48 32 0,000 0,05004378 0,06348631 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,05004378 0,06345131 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,05004378 0,06341635 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,05004378 0,06338143 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,05004378 0,06334655 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,05004378 0,06331171 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,05004378 0,0632769 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,05004378 0,06324213 ! peripheral nervous system development GO:0007422 53 32 0,000 0,05004378 0,0632074 ! regulation of protein stability GO:0031647 48 32 0,000 0,05004378 0,06317271 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,05004378 0,06313806 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,05004378 0,06310345 ! cytokine production GO:0001816 44 32 0,000 0,05004378 0,06306887 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,05004378 0,06303433 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,05004378 0,06299983 ! vesicle localization GO:0051648 47 32 0,000 0,05004378 0,06296536 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,05156806 0,06484775 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,05156806 0,06481232 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,05156806 0,06477692 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,05156806 0,06474156 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,05156806 0,06470624 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,05156806 0,06467096 ! sister chromatid segregation GO:0000819 46 33 0,000 0,05156806 0,06463572 ! ear morphogenesis GO:0042471 42 33 0,000 0,05156806 0,06460051 ! actomyosin structure organization GO:0031032 43 33 0,000 0,05156806 0,06456535 ! cell junction organization GO:0034330 63 33 0,000 0,05156806 0,06453022 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,05156806 0,06449513 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,05156806 0,06446008 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,05156806 0,06442506 GO:0042593|glucose homeostasis, ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,05156806 0,06439009 ! female gonad development GO:0008585 49 33 0,000 0,05156806 0,06435515 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,05156806 0,06432025 ! positive regulation of cell development GO:0010720 54 33 0,000 0,05156806 0,06428539 ! lipid homeostasis GO:0055088 55 33 0,000 0,05156806 0,06425056 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,05156806 0,06421578 ! regulation of proteolysis GO:0030162 50 33 0,000 0,05156806 0,06418103 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,05156806 0,06414632 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,05156806 0,06411164 ! cytokinesis GO:0000910 52 33 0,000 0,05156806 0,06407701 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,05156806 0,06404241 ! mRNA catabolic process GO:0006402 48 34 0,000 0,05308999 0,06589691 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,05308999 0,06586136 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,05308999 0,06582586 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,05308999 0,06579039 ! feeding behavior GO:0007631 45 34 0,000 0,05308999 0,06575497 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,05308999 0,06571957 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,05308999 0,06568422 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,05308999 0,06564891 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,05308999 0,06561363 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,05308999 0,06557839 ! neuron migration GO:0001764 46 34 0,000 0,05308999 0,06554319 ! female gamete generation GO:0007292 43 34 0,000 0,05308999 0,06550803 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,05308999 0,06547291 ! polyol metabolic process GO:0019751 44 34 0,000 0,05308999 0,06543782 ! aerobic respiration GO:0009060 47 34 0,000 0,05308999 0,06540277 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,05308999 0,06536776 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,05308999 0,06533278 ! embryonic organ development GO:0048568 45 34 0,000 0,05308999 0,06529785 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,05308999 0,06526295 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,05460956 0,06709508 ! Notch signaling pathway GO:0007219 56 35 0,000 0,05460956 0,06705925 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,05460956 0,06702347 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,05460956 0,06698773 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,05460956 0,06695202 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,05460956 0,06691635 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,05460956 0,06688072 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,05460956 0,06684512 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,05460956 0,06680957 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,05460956 0,06677405 ! glycogen metabolic process GO:0005977 48 35 0,000 0,05460956 0,06673857 ! pigment metabolic process GO:0042440 61 35 0,000 0,05460956 0,06670313 ! protein homooligomerization GO:0051260 52 35 0,000 0,05460956 0,06666772 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,05612678 0,0684836 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,05612678 0,06844729 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,05612678 0,06841102 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,05612678 0,06837478 ! negative regulation of binding GO:0051100 58 36 0,000 0,05612678 0,06833859 ! organic ether metabolic process GO:0018904 46 36 0,000 0,05612678 0,06830243 ! tissue remodeling GO:0048771 62 36 0,000 0,05612678 0,06826631 ! neural tube development GO:0021915 50 36 0,000 0,05612678 0,06823023 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,05612678 0,06819418 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,05612678 0,06815818 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,05612678 0,06812221 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,05612678 0,06808628 ! glucan metabolic process GO:0044042 49 36 0,000 0,05612678 0,06805039 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,05764165 0,06985026 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,05764165 0,06981348 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,05764165 0,06977673 ! learning GO:0007612 67 37 0,000 0,05764165 0,06974003 ! ion transmembrane transport GO:0034220 56 37 0,000 0,05764165 0,06970336 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,05764165 0,06966673 ! regulation of protein secretion GO:0050708 51 37 0,000 0,05764165 0,06963014 ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,05764165 0,06959359 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,05915418 0,07138227 ! gliogenesis GO:0042063 71 38 0,000 0,05915418 0,07134484 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,05915418 0,07130745 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,05915418 0,07127009 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,05915418 0,07123278 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,05915418 0,0711955 ! phagocytosis GO:0006909 60 38 0,000 0,05915418 0,07115827 ! mesenchymal cell development GO:0014031 64 38 0,000 0,05915418 0,07112107 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,05915418 0,07108391 ! maintenance of location in cell GO:0051651 69 38 0,000 0,05915418 0,07104679 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,06066436 0,07282256 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,06066436 0,07278458 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,06066436 0,07274663 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,06066436 0,07270872 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,06066436 0,07267085 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,06066436 0,07263302 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,06066436 0,07259523 ! male sex differentiation GO:0046661 53 39 0,000 0,06066436 0,07255748 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,06066436 0,07251977 ! chromatin remodeling GO:0006338 68 39 0,000 0,06066436 0,0724821 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,06066436 0,07244446 ! JNK cascade GO:0007254 54 39 0,000 0,06066436 0,07240687 ! developmental growth GO:0048589 62 39 0,000 0,06066436 0,07236931 ! cell growth GO:0016049 61 39 0,000 0,06066436 0,0723318 ! synapse organization GO:0050808 55 39 0,000 0,06066436 0,07229432 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,06217221 0,07405287 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,06217221 0,07401454 ! regulation of tube size GO:0035150 60 40 0,000 0,06217221 0,07397625 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,06217221 0,073938 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,06217221 0,07389979 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,06217221 0,07386161 ! peptide metabolic process GO:0006518 56 40 0,000 0,06217221 0,07382348 ! inner ear development GO:0048839 57 40 0,000 0,06217221 0,07378539 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,06217221 0,07374734 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,06217221 0,07370932 ! double-strand break repair GO:0006302 67 40 0,000 0,06217221 0,07367135 ! B cell differentiation GO:0030183 62 40 0,000 0,06217221 0,07363341 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,06217221 0,07359551 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,06217221 0,07355766 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,06367773 0,07530014 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,06367773 0,07526144 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,06367773 0,07522279 ! glucose transport GO:0015758 52 41 0,000 0,06367773 0,07518417 ! endosome transport GO:0016197 71 41 0,000 0,06367773 0,0751456 ! striated muscle contraction GO:0006941 62 41 0,000 0,06367773 0,07510706 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,06367773 0,07506856 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,06367773 0,07503011 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,06367773 0,07499169 ! biopolymer methylation GO:0043414 62 41 0,000 0,06367773 0,07495331 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,06367773 0,07491497 ! mitochondrial transport GO:0006839 60 42 0,000 0,06518091 0,07664422 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,06518091 0,07660505 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,06518091 0,07656593 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,06518091 0,07652685 ! cellular component disassembly GO:0022411 64 42 0,000 0,06518091 0,0764878 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,06518091 0,0764488 ! hexose transport GO:0008645 54 42 0,000 0,06518091 0,07640983 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,06518091 0,07637091 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,06518091 0,07633202 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,06518091 0,07629318 ! excretion GO:0007588 63 42 0,000 0,06518091 0,07625437 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,06518091 0,0762156 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,06518091 0,07617687 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,06518091 0,07613819 ! regulation of cell shape GO:0008360 78 42 0,000 0,06518091 0,07609954 ! positive regulation of binding GO:0051099 59 43 0,000 0,06668177 0,07781231 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,06668177 0,07777285 ! leukocyte migration GO:0050900 60 43 0,000 0,06668177 0,07773343 ! neuromuscular process GO:0050905 79 43 0,000 0,06668177 0,07769405 ! activation of caspase activity GO:0006919 65 43 0,000 0,06668177 0,07765471 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,06668177 0,07761541 ! tRNA processing GO:0008033 49 43 0,000 0,06668177 0,07757616 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,06668177 0,07753694 ! vesicle organization GO:0016050 79 43 0,000 0,06668177 0,07749776 ! response to insulin stimulus GO:0032868 63 43 0,000 0,06668177 0,07745862 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,06668177 0,07741952 ! methylation GO:0032259 64 43 0,000 0,06668177 0,07738045 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,0681803 0,07907952 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,0681803 0,07903966 ! regulation of action potential GO:0001508 71 44 0,000 0,0681803 0,07899984 ! regulation of ion transport GO:0043269 57 44 0,000 0,0681803 0,07896006 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,0681803 0,07892032 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,0681803 0,07888063 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,0681803 0,07884097 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,0681803 0,07880135 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,0681803 0,07876177 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,0681803 0,07872223 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,0681803 0,07868273 ! RNA catabolic process GO:0006401 64 45 0,000 0,06967651 0,08036909 ! positive regulation of defense response GO:0031349 59 45 0,000 0,06967651 0,08032881 ! regulation of translational initiation GO:0006446 64 45 0,000 0,06967651 0,08028856 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,06967651 0,08024836 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,06967651 0,08020819 ! cell recognition GO:0008037 58 45 0,000 0,06967651 0,08016807 ! cell maturation GO:0048469 60 45 0,000 0,06967651 0,08012799 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,06967651 0,08008794 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,07117041 0,0817642 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,07117041 0,08172338 ! cell redox homeostasis GO:0045454 63 46 0,000 0,07117041 0,0816826 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,07117041 0,08164186 ! regulation of ossification GO:0030278 71 46 0,000 0,07117041 0,08160116 ! histone modification GO:0016570 68 46 0,000 0,07117041 0,0815605 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,07117041 0,08151989 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,07266199 0,08318694 ! viral infectious cycle GO:0019058 71 47 0,000 0,07266199 0,08314556 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,07266199 0,08310421 ! endocrine system development GO:0035270 83 47 0,000 0,07266199 0,08306291 ! covalent chromatin modification GO:0016569 75 47 0,000 0,07266199 0,08302165 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,07266199 0,08298042 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,07266199 0,08293924 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,07266199 0,0828981 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,07266199 0,082857 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,07266199 0,08281594 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,07266199 0,08277492 ! chloride transport GO:0006821 67 48 0,000 0,07415126 0,08442965 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,07415126 0,08438788 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,07415126 0,08434614 ! response to temperature stimulus GO:0009266 62 48 0,000 0,07415126 0,08430445 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,07415126 0,0842628 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,07415126 0,08422118 ! gastrulation GO:0007369 73 48 0,000 0,07415126 0,08417961 ! heart morphogenesis GO:0003007 65 48 0,000 0,07415126 0,08413809 ! regulation of DNA replication GO:0006275 75 48 0,000 0,07415126 0,0840966 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,07415126 0,08405515 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,07415126 0,08401374 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,07415126 0,08397238 ! regulation of endocytosis GO:0030100 63 48 0,000 0,07415126 0,08393105 ! nuclear export GO:0051168 69 48 0,000 0,07415126 0,08388977 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,07415126 0,08384852 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,07415126 0,08380732 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,07563823 0,08544593 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,07563823 0,08540399 ! sensory perception of smell GO:0007608 61 49 0,000 0,07563823 0,08536208 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,07563823 0,08532022 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,07563823 0,08527839 ! RNA elongation GO:0006354 62 49 0,000 0,07563823 0,08523661 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,07563823 0,08519487 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,07563823 0,08515317 ! germ cell development GO:0007281 68 49 0,000 0,07563823 0,08511151 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,07563823 0,08506989 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,07563823 0,08502831 ! cartilage development GO:0051216 70 49 0,000 0,07563823 0,08498677 ! maintenance of location GO:0051235 84 49 0,000 0,07563823 0,08494527 ! regulation of actin filament length GO:0030832 72 50 0,000 0,07712289 0,08657035 ! ear development GO:0043583 72 50 0,000 0,07712289 0,08652812 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,07712289 0,08648593 ! membrane fusion GO:0006944 80 50 0,000 0,07712289 0,08644378 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,07712289 0,08640168 ! lipid modification GO:0030258 73 50 0,000 0,07712289 0,08635961 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,07712289 0,08631759 ! proton transport GO:0015992 75 50 0,000 0,07712289 0,08627561 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,07712289 0,08623366 ! positive regulation of secretion GO:0051047 71 51 0,000 0,07860525 0,08784844 ! hydrogen transport GO:0006818 77 51 0,000 0,07860525 0,08780577 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,07860525 0,08776315 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,07860525 0,08772056 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,07860525 0,08767802 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,07860525 0,08763552 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,07860525 0,08759306 ! adult behavior GO:0030534 80 51 0,000 0,07860525 0,08755064 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,07860525 0,08750827 ! transition metal ion transport GO:0000041 74 52 0,000 0,08008532 0,08911284 ! regulation of cellular component size GO:0032535 74 52 0,000 0,08008532 0,08906975 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,08008532 0,0890267 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,08008532 0,08898369 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,08008532 0,08894072 ! establishment of organelle localization GO:0051656 85 52 0,000 0,08008532 0,0888978 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,08156309 0,09049451 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,08156309 0,09045088 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,08156309 0,09040729 ! kidney development GO:0001822 90 53 0,000 0,08156309 0,09036374 ! single fertilization GO:0007338 59 53 0,000 0,08156309 0,09032023 ! amino acid transport GO:0006865 84 54 0,000 0,08303858 0,09190988 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,08303858 0,09186567 ! regulation of mitosis GO:0007088 84 54 0,000 0,08303858 0,09182151 GO:0051783|regulation of nuclear division, ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,08303858 0,09177738 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,08303858 0,0917333 ! DNA catabolic process GO:0006308 67 54 0,000 0,08303858 0,09168926 ! detection of external stimulus GO:0009581 66 54 0,000 0,08303858 0,09164527 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,08303858 0,09160131 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,08303858 0,0915574 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,08303858 0,09151353 ! exocytosis GO:0006887 74 55 0,000 0,08451178 0,09309248 ! mesoderm development GO:0007498 76 55 0,000 0,08451178 0,09304791 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,08451178 0,09300339 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,08451178 0,09295892 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,0859827 0,09453165 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,0859827 0,09448648 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,0859827 0,09444136 ! carbohydrate transport GO:0008643 74 57 0,000 0,08745133 0,09600862 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,08745133 0,09596282 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,08745133 0,09591706 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,08745133 0,09587134 ! camera-type eye development GO:0043010 88 57 0,000 0,08745133 0,09582566 ! secondary metabolic process GO:0019748 84 57 0,000 0,08745133 0,09578003 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,08745133 0,09573444 ! developmental maturation GO:0021700 75 57 0,000 0,08745133 0,0956889 ! gonad development GO:0008406 79 57 0,000 0,08745133 0,0956434 ! viral reproductive process GO:0022415 87 58 0,000 0,0889177 0,0972009 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,0889177 0,09715473 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,0889177 0,0971086 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,0889177 0,09706251 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,09038179 0,0986139 ! activation of MAPK activity GO:0000187 84 59 0,000 0,09038179 0,09856715 ! lung development GO:0030324 94 59 0,000 0,09038179 0,09852043 ! actin filament organization GO:0007015 95 59 0,000 0,09038179 0,09847376 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,09038179 0,09842713 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,09038179 0,09838055 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,09184361 0,09992445 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,09184361 0,09987721 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,09184361 0,09983001 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,09184361 0,09978285 ! regulation of heart contraction GO:0008016 91 60 0,000 0,09184361 0,09973574 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,09184361 0,09968867 ! fertilization GO:0009566 68 60 0,000 0,09184361 0,09964165 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,09184361 0,09959467 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,09330316 0,10112972 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,09330316 0,10108209 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,09330316 0,1010345 ! urogenital system development GO:0001655 101 61 0,000 0,09330316 0,10098695 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,09330316 0,10093945 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,09330316 0,100892 ! extracellular matrix organization GO:0030198 103 61 0,000 0,09330316 0,10084458 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,09330316 0,10079722 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,09476046 0,1023235 ! neurotransmitter transport GO:0006836 81 62 0,000 0,09476046 0,10227548 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,09476046 0,10222751 ! respiratory tube development GO:0030323 99 62 0,000 0,09476046 0,10217958 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,09476046 0,1021317 ! organelle localization GO:0051640 96 62 0,000 0,09476046 0,10208386 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,09621549 0,10360282 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,09621549 0,10355434 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,09621549 0,10350591 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,09621549 0,10345752 ! viral reproduction GO:0016032 92 63 0,000 0,09621549 0,10340917 ! regulation of lipase activity GO:0060191 109 63 0,000 0,09621549 0,10336087 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,09766827 0,10487256 ! appendage morphogenesis GO:0035107 93 64 0,000 0,09766827 0,10482362 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,09766827 0,10477473 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,09766827 0,10472589 ! respiratory system development GO:0060541 100 64 0,000 0,09766827 0,10467708 ! adaptive immune response GO:0002250 94 64 0,000 0,09766827 0,10462833 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,0991188 0,10613279 ! appendage development GO:0048736 94 65 0,000 0,0991188 0,1060834 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,0991188 0,10603406 ! defense response to bacterium GO:0042742 73 65 0,000 0,0991188 0,10598477 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,0991188 0,10593552 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,0991188 0,10588632 ! activation of immune response GO:0002253 83 65 0,000 0,0991188 0,10583716 ! protein oligomerization GO:0051259 100 65 0,000 0,0991188 0,10578805 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,10056708 0,10728399 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,10056708 0,10723425 ! antigen processing and presentation GO:0019882 96 66 0,000 0,10056708 0,10718456 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,10056708 0,10713491 ! regulation of immune effector process GO:0002697 101 66 0,000 0,10056708 0,10708531 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,10201311 0,10857481 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,10201311 0,10852459 ! acute inflammatory response GO:0002526 92 68 0,000 0,1034569 0,11000965 ! learning or memory GO:0007611 123 68 0,000 0,1034569 0,10995882 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,1034569 0,10990803 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,1034569 0,10985728 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,1034569 0,10980659 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,1034569 0,10975594 ! rhythmic process GO:0048511 105 68 0,000 0,1034569 0,10970534 ! inorganic anion transport GO:0015698 93 68 0,000 0,1034569 0,10965478 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,10489846 0,11113148 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,10489846 0,11108032 ! response to drug GO:0042493 108 69 0,000 0,10489846 0,1110292 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,10633777 0,11250087 ! humoral immune response GO:0006959 86 70 0,000 0,10633777 0,11244914 ! eye development GO:0001654 111 70 0,000 0,10633777 0,11239746 ! amine transport GO:0015837 101 70 0,000 0,10633777 0,11234583 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,10633777 0,11229425 ! regulation of catabolic process GO:0009894 106 70 0,000 0,10633777 0,11224272 ! muscle cell differentiation GO:0042692 104 71 0,000 0,10777486 0,11370742 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,10777486 0,11365529 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,10777486 0,1136032 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,10777486 0,11355116 ! response to hypoxia GO:0001666 132 72 0,000 0,10920972 0,11501023 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,10920972 0,1149576 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,10920972 0,11490501 ! negative regulation of transport GO:0051051 116 73 0,000 0,11064235 0,11635912 ! regulation of blood pressure GO:0008217 107 73 0,000 0,11064235 0,11630594 ! tube morphogenesis GO:0035239 118 73 0,000 0,11064235 0,11625281 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,11064235 0,11619973 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,11064235 0,11614669 ! response to oxygen levels GO:0070482 137 74 0,000 0,11207276 0,11759459 ! digestion GO:0007586 97 74 0,000 0,11207276 0,11754097 ! protein import into nucleus GO:0006606 118 74 0,000 0,11207276 0,1174874 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,11207276 0,11743387 ! blood coagulation GO:0007596 116 75 0,000 0,11350095 0,11887622 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 0,000 0,11350095 0,11882212 ! nuclear import GO:0051170 121 75 0,000 0,11350095 0,11876806 ! amine biosynthetic process GO:0009309 97 76 0,000 0,11492693 0,12020552 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,11492693 0,12015088 ! regulation of protein transport GO:0051223 114 76 0,000 0,11492693 0,12009629 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,11635069 0,12152888 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,11635069 0,12147372 ! regulation of DNA binding GO:0051101 119 77 0,000 0,11635069 0,1214186 ! gland development GO:0048732 148 77 0,000 0,11635069 0,12136353 ! sex differentiation GO:0007548 105 77 0,000 0,11635069 0,12130852 ! protein ubiquitination GO:0016567 125 77 0,000 0,11635069 0,12125355 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,11635069 0,12119864 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,11635069 0,12114377 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,11635069 0,12108896 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,11777225 0,12251297 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,11777225 0,12245758 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,1191916 0,1238774 ! cellular respiration GO:0045333 107 79 0,000 0,1191916 0,12382145 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,1191916 0,12376554 ! T cell activation GO:0042110 134 79 0,000 0,1191916 0,12370969 ! regulation of lyase activity GO:0051339 133 79 0,000 0,1191916 0,12365389 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,1191916 0,12359814 ! chromatin assembly GO:0031497 102 80 0,000 0,12060875 0,12501132 GO:0006334|nucleosome assembly, ! protein localization in nucleus GO:0034504 133 80 0,000 0,12060875 0,12495501 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,12060875 0,12489875 ! forebrain development GO:0030900 131 80 0,000 0,12060875 0,12484254 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,1220237 0,12625034 ! hemostasis GO:0007599 125 81 0,000 0,1220237 0,12619357 ! mRNA transport GO:0051028 121 81 0,000 0,1220237 0,12613686 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,1220237 0,12608019 ! regulation of neurological system process GO:0031644 122 81 0,000 0,1220237 0,12602358 ! vitamin metabolic process GO:0006766 103 81 0,000 0,1220237 0,12596701 ! ossification GO:0001503 134 82 0,000 0,12343645 0,12736825 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,12343645 0,12731114 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,12484701 0,12870826 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,12484701 0,1286506 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,12484701 0,12859298 ! regulation of defense response GO:0031347 117 84 0,000 0,12625539 0,1299854 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,12625539 0,12992724 ! sterol metabolic process GO:0016125 120 84 0,000 0,12625539 0,12986914 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,12766157 0,13125687 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,12766157 0,13119822 ! rRNA metabolic process GO:0016072 107 85 0,000 0,12766157 0,13113963 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,12766157 0,13108108 ! transcription initiation GO:0006352 118 85 0,000 0,12766157 0,13102259 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,12766157 0,13096415 ! regulation of protein localization GO:0032880 132 85 0,000 0,12766157 0,13090576 ! regulation of membrane potential GO:0042391 128 85 0,000 0,12766157 0,13084743 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,12766157 0,13078914 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,12906558 0,13216867 ! nucleosome organization GO:0034728 114 87 0,000 0,13046741 0,13354474 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,13046741 0,13348534 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,13046741 0,13342598 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,13046741 0,13336668 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,13046741 0,13330743 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,13046741 0,13324824 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,13186706 0,13461794 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,13186706 0,13455822 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,13186706 0,13449855 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,13186706 0,13443893 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,13186706 0,13437937 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,13326453 0,13574332 ! reproductive developmental process GO:0003006 127 89 0,000 0,13326453 0,13568323 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,13326453 0,1356232 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,13326453 0,13556321 ! regulation of T cell activation GO:0050863 128 89 0,000 0,13326453 0,13550328 ! leukocyte differentiation GO:0002521 143 90 0,000 0,13465984 0,13686153 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,13465984 0,13680108 ! hormone metabolic process GO:0042445 121 90 0,000 0,13465984 0,13674068 ! RNA localization GO:0006403 135 91 0,000 0,13605298 0,13809438 ! ATP metabolic process GO:0046034 137 91 0,000 0,13605298 0,13803346 ! response to virus GO:0009615 122 91 0,000 0,13605298 0,1379726 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,13744396 0,13932178 ! cell fate commitment GO:0045165 141 92 0,000 0,13744396 0,1392604 ! positive regulation of immune response GO:0050778 121 92 0,000 0,13744396 0,13919908 ! DNA recombination GO:0006310 146 92 0,000 0,13744396 0,13913781 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,13883278 0,14048192 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,13883278 0,14042014 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,13883278 0,14035842 ! electron transport chain GO:0022900 123 94 0,000 0,14021944 0,14169803 ! response to oxidative stress GO:0006979 141 94 0,000 0,14021944 0,1416358 ! regulation of binding GO:0051098 151 95 0,000 0,14160395 0,14297151 ! angiogenesis GO:0001525 149 95 0,000 0,14160395 0,14290877 ! carboxylic acid transport GO:0046942 147 95 0,000 0,14160395 0,14284609 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,14298631 0,14417734 ! in utero embryonic development GO:0001701 147 96 0,000 0,14298631 0,14411416 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,14298631 0,14405104 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,14298631 0,14398797 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,14298631 0,14392496 ! protein maturation GO:0051604 129 96 0,000 0,14298631 0,143862 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,14436653 0,14518715 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,14436653 0,14512369 ! calcium ion transport GO:0006816 167 99 0,000 0,14712053 0,14782753 ! extracellular structure organization GO:0043062 156 99 0,000 0,14712053 0,14776297 ! protein import GO:0017038 156 99 0,000 0,14712053 0,14769848 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,14712053 0,14763404 ! regulation of translation GO:0006417 151 100 0,000 0,14849432 0,14894764 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,14849432 0,14888271 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,14849432 0,14881783 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,14849432 0,14875302 ! divalent metal ion transport GO:0070838 171 100 0,000 0,14849432 0,14868826 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,14849432 0,14862356 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,14849432 0,14855891 ! protein localization in organelle GO:0033365 161 100 0,000 0,14849432 0,14849432