pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/2068-2-real-Loi_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 2,327E-09 5,599E-06 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 2,000 2,802E-08 3,371E-05 ! nucleoside diphosphate metabolic process GO:0009132 13 9 2,000 6,716E-08 5,386E-05 ! response to UV GO:0009411 104 53 3,000 1,964E-07 1,182E-04 ! deoxyribonucleotide metabolic process GO:0009262 32 22 2,000 1,221E-06 5,875E-04 ! negative regulation of protein ubiquitination GO:0031397 9 5 1,000 8,937E-06 3,584E-03 ! activation of Ras GTPase activity GO:0032856 10 5 1,000 8,937E-06 3,072E-03 GO:0032862|activation of Rho GTPase activity, ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 1,108E-05 3,334E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 1,185E-05 3,168E-03 ! epidermal cell differentiation GO:0009913 68 46 2,000 1,185E-05 2,851E-03 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 1,000 1,874E-05 4,1E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,498E-05 5,008E-03 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 1,000 2,498E-05 4,623E-03 ! regulation of focal adhesion formation GO:0051893 22 8 1,000 2,498E-05 4,293E-03 ! keratinocyte proliferation GO:0043616 14 9 1,000 3,209E-05 5,148E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 3,209E-05 4,826E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 3,689E-05 5,221E-03 ! negative regulation of kinase activity GO:0033673 131 68 2,000 3,857E-05 5,155E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 4,009E-05 5,077E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 4,009E-05 4,823E-03 ! regulation of phosphatase activity GO:0010921 28 10 1,000 4,009E-05 4,594E-03 ! regulation of stress fiber formation GO:0051492 30 10 1,000 4,009E-05 4,385E-03 ! positive regulation of Rho GTPase activity GO:0032321 24 10 1,000 4,009E-05 4,194E-03 ! negative regulation of transferase activity GO:0051348 140 72 2,000 4,578E-05 4,589E-03 ! UV protection GO:0009650 19 11 1,000 4,897E-05 4,713E-03 ! regulation of actin filament bundle formation GO:0032231 33 11 1,000 4,897E-05 4,532E-03 ! protein oligomerization GO:0051259 139 78 2,000 5,817E-05 5,183E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 5,873E-05 5,047E-03 ! positive regulation of cell growth GO:0030307 22 12 1,000 5,873E-05 4,873E-03 ! positive regulation of Ras GTPase activity GO:0032320 35 13 1,000 6,937E-05 5,564E-03 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 8,089E-05 6,278E-03 ! negative regulation of caspase activity GO:0043154 22 14 1,000 8,089E-05 6,082E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 8,089E-05 5,897E-03 ! positive regulation of cell size GO:0045793 27 15 1,000 9,327E-05 6,601E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 1,047E-04 7,196E-03 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 1,065E-04 7,12E-03 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 1,065E-04 6,928E-03 GO:0031114|regulation of microtubule depolymerization, ! regulation of dephosphorylation GO:0035303 43 16 1,000 1,065E-04 6,745E-03 ! interphase GO:0051325 213 98 2,000 1,148E-04 7,082E-03 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 1,207E-04 7,258E-03 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 1,207E-04 7,081E-03 ! skin development GO:0043588 36 19 1,000 1,515E-04 8,681E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,515E-04 8,479E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,683E-04 9,202E-03 ! negative regulation of translation GO:0017148 29 20 1,000 1,683E-04 8,997E-03 ! regulation of Rho GTPase activity GO:0032319 43 21 1,000 1,859E-04 9,722E-03 ! positive regulation of B cell activation GO:0050871 38 22 1,000 2,043E-04 0,01046083 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 2,043E-04 0,01024289 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 2,237E-04 0,0109829 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 1,000 2,237E-04 0,01076324 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 2,237E-04 0,0105522 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 2,439E-04 0,01128337 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 2,439E-04 0,01107048 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 2,439E-04 0,01086547 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 2,649E-04 0,01158864 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 2,649E-04 0,0113817 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 2,649E-04 0,01118202 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 2,868E-04 0,01189789 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 3,096E-04 0,01262438 ! fat cell differentiation GO:0045444 50 27 1,000 3,096E-04 0,01241398 ! negative regulation of protein modification process GO:0031400 60 28 1,000 3,332E-04 0,01314189 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 3,332E-04 0,01292992 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 3,577E-04 0,01365909 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 3,577E-04 0,01344567 ! regulation of B cell activation GO:0050864 50 30 1,000 3,83E-04 0,01417598 ! spindle organization GO:0007051 46 32 1,000 4,362E-04 0,01589997 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 5,223E-04 0,01875525 ! regulation of microtubule-based process GO:0032886 78 35 1,000 5,223E-04 0,01847944 ! RNA export from nucleus GO:0006405 56 37 1,000 5,839E-04 0,02036045 ! meiosis I GO:0007127 65 37 1,000 5,839E-04 0,02006959 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 6,16E-04 0,02087373 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! keratinocyte differentiation GO:0030216 62 41 1,000 7,172E-04 0,02396663 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 7,526E-04 0,02480543 ! response to insulin stimulus GO:0032868 95 46 1,000 9,026E-04 0,0293453 ! response to calcium ion GO:0051592 81 47 1,000 9,421E-04 0,03022284 ! positive regulation of cell cycle GO:0045787 89 48 1,000 9,825E-04 0,03110336 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 9,825E-04 0,03069942 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 1,024E-03 0,03157661 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 1,109E-03 0,03376119 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 1,109E-03 0,03333918 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of growth GO:0045927 90 52 1,000 1,152E-03 0,03422427 ! regulation of translational initiation GO:0006446 82 53 1,000 1,197E-03 0,03511171 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 1,242E-03 0,03600138 ! RNA elongation GO:0006354 79 55 1,000 1,288E-03 0,03689316 ! nuclear export GO:0051168 97 55 1,000 1,288E-03 0,03645912 ! nucleotide-excision repair GO:0006289 83 56 1,000 1,335E-03 0,03734754 ! DNA catabolic process GO:0006308 86 59 1,000 1,481E-03 0,04094432 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 1,531E-03 0,04184991 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 1,582E-03 0,04275689 ! negative regulation of cell growth GO:0030308 132 67 1,000 1,904E-03 0,05090239 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 1,961E-03 0,05183767 ! cell cycle checkpoint GO:0000075 137 69 1,000 2,018E-03 0,05277333 ! negative regulation of cell size GO:0045792 134 69 1,000 2,018E-03 0,05220588 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 2,018E-03 0,05165049 ! regulation of caspase activity GO:0043281 122 72 1,000 2,195E-03 0,05558214 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 2,195E-03 0,05500316 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 2,195E-03 0,05443612 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 2,195E-03 0,05388065 ! meiosis GO:0007126 121 74 1,000 2,316E-03 0,05629501 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 2,316E-03 0,05573206 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 2,316E-03 0,05518026 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 2,378E-03 0,05610281 ! meiotic cell cycle GO:0051321 122 75 1,000 2,378E-03 0,05555813 ! regulation of actin filament-based process GO:0032970 152 77 1,000 2,505E-03 0,05794893 ! positive regulation of ligase activity GO:0051351 124 77 1,000 2,505E-03 0,05739704 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 2,505E-03 0,05685555 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 2,569E-03 0,05777199 ! negative regulation of organelle organization GO:0010639 161 78 1,000 2,569E-03 0,05723706 ! regulation of peptidase activity GO:0052547 134 79 1,000 2,634E-03 0,05815035 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 2,634E-03 0,05762171 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 2,634E-03 0,05710259 ! response to metal ion GO:0010038 140 80 1,000 2,7E-03 0,05800928 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 2,767E-03 0,05891642 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of growth GO:0045926 155 84 1,000 2,972E-03 0,06272151 ! regulation of ligase activity GO:0051340 142 84 1,000 2,972E-03 0,06217611 ! response to unfolded protein GO:0006986 131 85 1,000 3,042E-03 0,06308784 ! positive regulation of cell activation GO:0050867 145 85 1,000 3,042E-03 0,06254862 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 3,112E-03 0,06345739 ! mitochondrion organization GO:0007005 148 86 1,000 3,112E-03 0,06292414 ! positive regulation of protein modification process GO:0031401 136 88 1,000 3,256E-03 0,06527553 ! regulation of cell adhesion GO:0030155 212 89 1,000 3,328E-03 0,06618484 ! response to protein stimulus GO:0051789 149 91 1,000 3,477E-03 0,06856118 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 3,628E-03 0,07095825 GO:0010498|proteasomal protein catabolic process, ! transcription initiation GO:0006352 153 94 1,000 3,704E-03 0,07187335 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 3,782E-03 0,07278833 ! cell cycle arrest GO:0007050 213 100 1,000 4,18E-03 0,07981654 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 4,806E-03 0,09104175 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 4,806E-03 0,09033049 ! positive regulation of helicase activity GO:0051096 11 5 0,000 4,806E-03 0,08963025 ! neuron fate determination GO:0048664 7 5 0,000 4,806E-03 0,08894079 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 4,806E-03 0,08826185 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 4,806E-03 0,0875932 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 4,806E-03 0,08693461 ! polyol transport GO:0015791 12 5 0,000 4,806E-03 0,08628584 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 4,806E-03 0,08564669 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 4,806E-03 0,08501693 ! response to superoxide GO:0000303 10 5 0,000 4,806E-03 0,08439637 ! negative regulation of bone resorption GO:0045779 10 5 0,000 4,806E-03 0,0837848 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 4,806E-03 0,08318203 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 4,806E-03 0,08258788 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 4,806E-03 0,08200215 ! female meiosis GO:0007143 7 5 0,000 4,806E-03 0,08142467 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 4,806E-03 0,08085526 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 4,806E-03 0,08029377 ! cobalt ion transport GO:0006824 11 5 0,000 4,806E-03 0,07974002 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 4,806E-03 0,07919385 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 4,806E-03 0,07865512 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 4,806E-03 0,07812367 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 4,806E-03 0,07759935 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 4,806E-03 0,07708202 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 4,806E-03 0,07657154 ! embryonic camera-type eye development GO:0031076 10 5 0,000 4,806E-03 0,07606778 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 4,806E-03 0,0755706 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 4,806E-03 0,07507989 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 4,806E-03 0,0745955 ! adaptation of signaling pathway GO:0022401 7 5 0,000 4,806E-03 0,07411732 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 4,806E-03 0,07364524 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 4,806E-03 0,07317913 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 4,806E-03 0,07271888 ! negative chemotaxis GO:0050919 14 5 0,000 4,806E-03 0,07226439 ! positive regulation of histone modification GO:0031058 5 5 0,000 4,806E-03 0,07181554 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 4,806E-03 0,07137224 ! sensory perception of bitter taste GO:0050913 7 5 0,000 4,806E-03 0,07093437 ! behavioral response to pain GO:0048266 9 5 0,000 4,806E-03 0,07050184 ! clathrin coat assembly GO:0048268 14 5 0,000 4,806E-03 0,07007456 ! Notch receptor processing GO:0007220 8 5 0,000 4,806E-03 0,06965242 ! regulation of dopamine uptake GO:0051584 9 5 0,000 4,806E-03 0,06923534 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 4,806E-03 0,06882323 ! micturition GO:0060073 9 5 0,000 4,806E-03 0,06841599 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 4,806E-03 0,06801354 ! copulation GO:0007620 9 5 0,000 4,806E-03 0,0676158 ! glial cell fate commitment GO:0021781 13 5 0,000 4,806E-03 0,06722269 ! protein maturation by protein folding GO:0022417 13 5 0,000 4,806E-03 0,06683412 ! spermidine metabolic process GO:0008216 7 5 0,000 4,806E-03 0,06645001 ! regulation of potassium ion transport GO:0043266 10 5 0,000 4,806E-03 0,0660703 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 4,806E-03 0,0656949 ! apoptotic cell clearance GO:0043277 20 5 0,000 4,806E-03 0,06532374 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 4,806E-03 0,06495676 ! lipoprotein particle clearance GO:0034381 10 5 0,000 4,806E-03 0,06459387 ! grooming behavior GO:0007625 6 5 0,000 4,806E-03 0,06423501 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 4,806E-03 0,06388012 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 4,806E-03 0,06352913 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 4,806E-03 0,06318198 ! response to protozoan GO:0001562 10 5 0,000 4,806E-03 0,0628386 ! positive regulation of glycolysis GO:0045821 14 5 0,000 4,806E-03 0,06249893 ! lymph vessel development GO:0001945 10 5 0,000 4,806E-03 0,06216292 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 4,806E-03 0,06183049 ! endochondral ossification GO:0001958 16 5 0,000 4,806E-03 0,06150161 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 4,806E-03 0,0611762 ! parathyroid gland development GO:0060017 13 5 0,000 4,806E-03 0,06085422 ! anagen GO:0042640 6 5 0,000 4,806E-03 0,06053562 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 4,806E-03 0,06022033 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 4,806E-03 0,0599083 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 4,806E-03 0,0595995 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 4,806E-03 0,05929386 ! dorsal spinal cord development GO:0021516 7 5 0,000 4,806E-03 0,05899134 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 4,806E-03 0,05869189 ! sphingoid catabolic process GO:0046521 6 5 0,000 4,806E-03 0,05839547 ! skeletal myofibril assembly GO:0014866 10 5 0,000 4,806E-03 0,05810202 ! smooth muscle tissue development GO:0048745 28 5 0,000 4,806E-03 0,05781151 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 4,806E-03 0,05752389 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 4,806E-03 0,05723912 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 4,806E-03 0,05695716 ! cardiac muscle fiber development GO:0048739 10 5 0,000 4,806E-03 0,05667795 ! transepithelial chloride transport GO:0030321 9 5 0,000 4,806E-03 0,05640148 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 4,806E-03 0,05612768 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 4,806E-03 0,05585653 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 4,806E-03 0,05558799 ! neutrophil mediated immunity GO:0002446 7 5 0,000 4,806E-03 0,05532202 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 4,806E-03 0,05505858 ! histidine catabolic process GO:0006548 6 5 0,000 4,806E-03 0,05479764 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 4,806E-03 0,05453916 ! microvillus organization GO:0032528 7 5 0,000 4,806E-03 0,05428311 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 4,806E-03 0,05402945 ! L-serine biosynthetic process GO:0006564 6 5 0,000 4,806E-03 0,05377815 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 4,806E-03 0,05352918 ! tryptophan metabolic process GO:0006568 9 5 0,000 4,806E-03 0,0532825 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 4,806E-03 0,05303809 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 4,806E-03 0,0527959 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 4,806E-03 0,05255592 ! polyol catabolic process GO:0046174 7 5 0,000 4,806E-03 0,05231811 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 4,806E-03 0,05208244 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 4,806E-03 0,05184889 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 4,806E-03 0,05161742 ! muscle cell migration GO:0014812 8 5 0,000 4,806E-03 0,05138801 ! mitochondrial fission GO:0000266 8 5 0,000 4,806E-03 0,05116063 ! sister chromatid cohesion GO:0007062 12 5 0,000 4,806E-03 0,05093525 ! mRNA transcription GO:0009299 9 5 0,000 4,806E-03 0,05071185 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 4,806E-03 0,0504904 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 4,806E-03 0,05027088 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 4,806E-03 0,05005326 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 4,806E-03 0,04983751 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 4,806E-03 0,04962362 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 4,806E-03 0,04941155 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 4,806E-03 0,04920129 ! response to food GO:0032094 6 5 0,000 4,806E-03 0,04899281 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 4,806E-03 0,04878609 ! positive regulation of transporter activity GO:0032411 8 5 0,000 4,806E-03 0,0485811 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 4,806E-03 0,04837783 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 4,806E-03 0,04817626 ! paraxial mesoderm development GO:0048339 14 5 0,000 4,806E-03 0,04797636 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 4,806E-03 0,04777811 ! forebrain neuron development GO:0021884 13 5 0,000 4,806E-03 0,04758149 ! lipoprotein catabolic process GO:0042159 11 5 0,000 4,806E-03 0,04738649 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 4,806E-03 0,04719307 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 4,806E-03 0,04700123 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 4,806E-03 0,04681094 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 4,806E-03 0,04662219 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 4,806E-03 0,04643495 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 4,806E-03 0,04624921 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 4,806E-03 0,04606495 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 4,806E-03 0,04588215 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 4,806E-03 0,0457008 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 4,806E-03 0,04552088 ! basic amino acid transport GO:0015802 11 5 0,000 4,806E-03 0,04534236 ! cellular glucose homeostasis GO:0001678 5 5 0,000 4,806E-03 0,04516524 ! early endosome to late endosome transport GO:0045022 12 5 0,000 4,806E-03 0,0449895 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 4,806E-03 0,04481513 ! depyrimidination GO:0045008 10 5 0,000 4,806E-03 0,04464209 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 4,806E-03 0,04447039 ! regulation of centrosome cycle GO:0046605 7 5 0,000 4,806E-03 0,04430001 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 4,806E-03 0,04413093 ! zinc ion homeostasis GO:0055069 8 5 0,000 4,806E-03 0,04396313 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 4,806E-03 0,0437966 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 4,806E-03 0,04363133 ! forebrain morphogenesis GO:0048853 13 5 0,000 4,806E-03 0,0434673 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 4,806E-03 0,0433045 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 4,806E-03 0,04314292 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 4,806E-03 0,04298254 ! peptidyl-arginine modification GO:0018195 9 5 0,000 4,806E-03 0,04282334 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4,806E-03 0,04266532 ! positive regulation of organ growth GO:0046622 6 5 0,000 4,806E-03 0,04250847 ! response to arsenic GO:0046685 10 5 0,000 4,806E-03 0,04235276 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 4,806E-03 0,04219818 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 4,806E-03 0,04204474 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 4,806E-03 0,0418924 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 4,806E-03 0,04174116 ! response to cadmium ion GO:0046686 7 5 0,000 4,806E-03 0,04159102 ! bile acid biosynthetic process GO:0006699 6 5 0,000 4,806E-03 0,04144194 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 4,806E-03 0,04129394 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 4,806E-03 0,04114698 ! decidualization GO:0046697 11 5 0,000 4,806E-03 0,04100107 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 4,806E-03 0,04085619 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 4,806E-03 0,04071233 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 4,806E-03 0,04056948 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 4,806E-03 0,04042763 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 4,806E-03 0,04028677 ! base conversion or substitution editing GO:0016553 5 5 0,000 4,806E-03 0,04014688 ! neural tube patterning GO:0021532 7 5 0,000 4,806E-03 0,04000797 ! embryonic cleavage GO:0040016 6 5 0,000 4,806E-03 0,03987001 ! peroxisome fission GO:0016559 5 5 0,000 4,806E-03 0,039733 ! histone demethylation GO:0016577 10 5 0,000 4,806E-03 0,03959693 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 4,806E-03 0,03946178 ! mitotic recombination GO:0006312 9 5 0,000 4,806E-03 0,03932756 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 4,806E-03 0,03919425 ! metaphase plate congression GO:0051310 7 5 0,000 4,806E-03 0,03906183 ! regulation of sterol transport GO:0032371 7 5 0,000 4,806E-03 0,03893031 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 4,806E-03 0,03879967 ! enteric nervous system development GO:0048484 8 5 0,000 4,806E-03 0,03866991 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 4,806E-03 0,03854101 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 4,806E-03 0,03841297 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 4,806E-03 0,03828577 ! muscle cell proliferation GO:0033002 11 5 0,000 4,806E-03 0,03815941 ! skeletal muscle regeneration GO:0043403 8 5 0,000 4,806E-03 0,03803389 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 4,806E-03 0,03790919 ! plasminogen activation GO:0031639 5 5 0,000 4,806E-03 0,0377853 ! B cell homeostasis GO:0001782 13 5 0,000 4,806E-03 0,03766222 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 4,806E-03 0,03753994 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 4,806E-03 0,03741845 ! metaphase GO:0051323 8 5 0,000 4,806E-03 0,03729775 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 4,806E-03 0,03717782 ! cellular response to nutrient GO:0031670 8 5 0,000 4,806E-03 0,03705866 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 4,806E-03 0,03694026 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 4,806E-03 0,03682262 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 4,806E-03 0,03670572 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 4,806E-03 0,03658957 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 4,806E-03 0,03647414 ! response to redox state GO:0051775 5 5 0,000 4,806E-03 0,03635944 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 4,806E-03 0,03624546 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 4,806E-03 0,0361322 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 4,806E-03 0,03601963 ! regulation of telomerase activity GO:0051972 6 5 0,000 4,806E-03 0,03590777 ! galactolipid metabolic process GO:0019374 7 5 0,000 4,806E-03 0,0357966 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 4,806E-03 0,03568612 ! porphyrin catabolic process GO:0006787 12 5 0,000 4,806E-03 0,03557632 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 4,806E-03 0,03546719 ! striatum development GO:0021756 9 5 0,000 4,806E-03 0,03535872 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 4,806E-03 0,03525092 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 4,806E-03 0,03514378 ! glial cell migration GO:0008347 11 5 0,000 4,806E-03 0,03503728 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 4,806E-03 0,03493143 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 4,806E-03 0,03482621 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 4,806E-03 0,03472163 ! somatic stem cell maintenance GO:0035019 15 5 0,000 4,806E-03 0,03461767 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 4,806E-03 0,03451434 ! negative regulation of lipase activity GO:0060192 8 5 0,000 4,806E-03 0,03441161 ! neuroprotection GO:0043526 6 5 0,000 4,806E-03 0,0343095 ! neural plate development GO:0001840 8 5 0,000 4,806E-03 0,034208 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 4,806E-03 0,03410709 ! regulation of sensory perception GO:0051931 7 5 0,000 4,806E-03 0,03400677 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 4,806E-03 0,03390705 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 4,806E-03 0,0338079 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 4,806E-03 0,03370934 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 4,806E-03 0,03361134 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 4,806E-03 0,03351392 ! sequestering of calcium ion GO:0051208 7 5 0,000 4,806E-03 0,03341706 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 4,806E-03 0,03332076 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 4,806E-03 0,03322501 ! spindle assembly GO:0051225 6 5 0,000 4,806E-03 0,03312981 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 4,806E-03 0,03303515 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 4,806E-03 0,03294103 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 4,806E-03 0,03284745 ! drug metabolic process GO:0017144 6 5 0,000 4,806E-03 0,0327544 ! stem cell division GO:0017145 11 5 0,000 4,806E-03 0,03266187 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 4,806E-03 0,03256987 ! organ regeneration GO:0031100 7 5 0,000 4,806E-03 0,03247838 ! carnitine metabolic process GO:0009437 7 5 0,000 4,806E-03 0,0323874 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 4,806E-03 0,03229693 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 4,806E-03 0,03220697 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 5,764E-03 0,0385231 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 5,764E-03 0,03841639 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 5,764E-03 0,03831027 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 5,764E-03 0,03820473 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 5,764E-03 0,03809977 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 5,764E-03 0,03799539 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 5,764E-03 0,03789158 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 5,764E-03 0,03778833 ! sleep GO:0030431 13 6 0,000 5,764E-03 0,03768564 ! response to oxygen radical GO:0000305 11 6 0,000 5,764E-03 0,03758351 ! positive regulation of axon extension GO:0045773 11 6 0,000 5,764E-03 0,03748194 ! myoblast cell fate commitment GO:0048625 16 6 0,000 5,764E-03 0,03738091 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 5,764E-03 0,03728042 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 5,764E-03 0,03718047 ! regulation of interferon-beta production GO:0032648 8 6 0,000 5,764E-03 0,03708106 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 5,764E-03 0,03698218 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 5,764E-03 0,03688382 ! forebrain regionalization GO:0021871 8 6 0,000 5,764E-03 0,03678599 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 5,764E-03 0,03668867 ! male meiosis GO:0007140 7 6 0,000 5,764E-03 0,03659186 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 5,764E-03 0,03649557 ! response to zinc ion GO:0010043 9 6 0,000 5,764E-03 0,03639978 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 5,764E-03 0,03630449 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 5,764E-03 0,0362097 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 5,764E-03 0,03611541 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 5,764E-03 0,0360216 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 5,764E-03 0,03592828 ! malate metabolic process GO:0006108 11 6 0,000 5,764E-03 0,03583544 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 5,764E-03 0,03574308 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 5,764E-03 0,0356512 ! protein refolding GO:0042026 15 6 0,000 5,764E-03 0,03555979 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 5,764E-03 0,03546884 ! opsonization GO:0008228 8 6 0,000 5,764E-03 0,03537836 ! mating behavior GO:0007617 7 6 0,000 5,764E-03 0,03528834 ! neuron remodeling GO:0016322 15 6 0,000 5,764E-03 0,03519877 ! erythrocyte maturation GO:0043249 7 6 0,000 5,764E-03 0,03510966 ! embryonic hemopoiesis GO:0035162 14 6 0,000 5,764E-03 0,035021 ! equilibrioception GO:0050957 14 6 0,000 5,764E-03 0,03493279 ! protein amino acid dealkylation GO:0008214 12 6 0,000 5,764E-03 0,03484502 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 5,764E-03 0,03475769 ! photoreceptor cell development GO:0042461 10 6 0,000 5,764E-03 0,03467079 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 5,764E-03 0,03458433 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 5,764E-03 0,0344983 ! response to interferon-gamma GO:0034341 15 6 0,000 5,764E-03 0,0344127 ! toxin metabolic process GO:0009404 11 6 0,000 5,764E-03 0,03432752 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 5,764E-03 0,03424276 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 5,764E-03 0,03415842 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 5,764E-03 0,03407449 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 5,764E-03 0,03399097 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 5,764E-03 0,03390786 ! cGMP-mediated signaling GO:0019934 13 6 0,000 5,764E-03 0,03382516 ! activation of MAPKKK activity GO:0000185 12 6 0,000 5,764E-03 0,03374286 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 5,764E-03 0,03366096 ! thymic T cell selection GO:0045061 12 6 0,000 5,764E-03 0,03357946 ! protein lipoylation GO:0009249 10 6 0,000 5,764E-03 0,03349835 ! cysteine metabolic process GO:0006534 10 6 0,000 5,764E-03 0,03341763 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 5,764E-03 0,0333373 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 5,764E-03 0,03325735 ! glutamate catabolic process GO:0006538 10 6 0,000 5,764E-03 0,03317779 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 5,764E-03 0,03309861 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 5,764E-03 0,0330198 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 5,764E-03 0,03294137 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 5,764E-03 0,03286331 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 5,764E-03 0,03278562 ! hyperosmotic response GO:0006972 9 6 0,000 5,764E-03 0,03270829 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 5,764E-03 0,03263133 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 5,764E-03 0,03255473 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 5,764E-03 0,03247849 ! urea metabolic process GO:0019627 7 6 0,000 5,764E-03 0,03240261 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 5,764E-03 0,03232708 ! neutrophil activation GO:0042119 8 6 0,000 5,764E-03 0,0322519 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 5,764E-03 0,03217707 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 5,764E-03 0,03210258 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 5,764E-03 0,03202844 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 5,764E-03 0,03195465 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 5,764E-03 0,03188119 ! neuron apoptosis GO:0051402 9 6 0,000 5,764E-03 0,03180807 ! nucleoside salvage GO:0043174 9 6 0,000 5,764E-03 0,03173528 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 5,764E-03 0,03166282 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 5,764E-03 0,0315907 ! T cell mediated immunity GO:0002456 16 6 0,000 5,764E-03 0,0315189 ! negative regulation of platelet activation GO:0010544 9 6 0,000 5,764E-03 0,03144743 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 5,764E-03 0,03137628 ! carnitine transport GO:0015879 10 6 0,000 5,764E-03 0,03130545 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 5,764E-03 0,03123495 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 5,764E-03 0,03116476 ! positive regulation of exocytosis GO:0045921 8 6 0,000 5,764E-03 0,03109488 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 5,764E-03 0,03102532 ! 5S class rRNA transcription GO:0042791 11 6 0,000 5,764E-03 0,03095606 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 5,764E-03 0,03088712 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 5,764E-03 0,03081848 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 5,764E-03 0,03075015 ! sodium ion homeostasis GO:0055078 11 6 0,000 5,764E-03 0,03068212 ! establishment of spindle localization GO:0051293 12 6 0,000 5,764E-03 0,03061439 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 5,764E-03 0,03054695 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 5,764E-03 0,03047982 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 5,764E-03 0,03041297 ! neural nucleus development GO:0048857 14 6 0,000 5,764E-03 0,03034643 ! response to UV-C GO:0010225 11 6 0,000 5,764E-03 0,03028017 ! astrocyte development GO:0014002 15 6 0,000 5,764E-03 0,0302142 ! protein targeting to lysosome GO:0006622 10 6 0,000 5,764E-03 0,03014851 ! purine base biosynthetic process GO:0009113 17 6 0,000 5,764E-03 0,03008312 ! interaction with symbiont GO:0051702 13 6 0,000 5,764E-03 0,030018 ! regulation of dendrite development GO:0050773 16 6 0,000 5,764E-03 0,02995317 ! skeletal muscle contraction GO:0003009 6 6 0,000 5,764E-03 0,02988861 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 5,764E-03 0,02982434 ! response to copper ion GO:0046688 10 6 0,000 5,764E-03 0,02976034 ! response to exogenous dsRNA GO:0043330 10 6 0,000 5,764E-03 0,02969661 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 5,764E-03 0,02963315 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 5,764E-03 0,02956997 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 5,764E-03 0,02950706 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 5,764E-03 0,02944441 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 5,764E-03 0,02938203 ! regulation of dopamine secretion GO:0014059 14 6 0,000 5,764E-03 0,02931991 ! nucleoside catabolic process GO:0009164 7 6 0,000 5,764E-03 0,02925805 ! hair follicle maturation GO:0048820 7 6 0,000 5,764E-03 0,02919646 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 5,764E-03 0,02913512 ! Schwann cell development GO:0014044 15 6 0,000 5,764E-03 0,02907404 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 5,764E-03 0,02901321 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 5,764E-03 0,02895264 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 5,764E-03 0,02889233 ! subpallium development GO:0021544 10 6 0,000 5,764E-03 0,02883226 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 5,764E-03 0,02877244 ! histone ubiquitination GO:0016574 8 6 0,000 5,764E-03 0,02871287 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 5,764E-03 0,02865355 ! maintenance of organ identity GO:0048496 9 6 0,000 5,764E-03 0,02859447 ! G2 phase GO:0051319 16 6 0,000 5,764E-03 0,02853563 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 5,764E-03 0,02847704 ! establishment of planar polarity GO:0001736 7 6 0,000 5,764E-03 0,02841868 ! regulation of mast cell activation GO:0033003 12 6 0,000 5,764E-03 0,02836057 ! membrane to membrane docking GO:0022614 14 6 0,000 5,764E-03 0,02830269 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 5,764E-03 0,02824504 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 5,764E-03 0,02818764 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 5,764E-03 0,02813046 ! receptor internalization GO:0031623 10 6 0,000 5,764E-03 0,02807352 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 5,764E-03 0,0280168 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 5,764E-03 0,02796032 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 5,764E-03 0,02790406 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 5,764E-03 0,02784803 ! protein deubiquitination GO:0016579 14 6 0,000 5,764E-03 0,02779222 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 5,764E-03 0,02773663 ! protein destabilization GO:0031648 9 6 0,000 5,764E-03 0,02768127 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 5,764E-03 0,02762613 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 5,764E-03 0,02757121 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 5,764E-03 0,0275165 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 5,764E-03 0,02746201 ! progesterone metabolic process GO:0042448 10 6 0,000 5,764E-03 0,02740774 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 5,764E-03 0,02735368 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 5,764E-03 0,02729984 ! negative regulation of axon extension GO:0030517 21 6 0,000 5,764E-03 0,0272462 ! removal of superoxide radicals GO:0019430 11 6 0,000 5,764E-03 0,02719278 ! triglyceride catabolic process GO:0019433 10 6 0,000 5,764E-03 0,02713956 ! determination of adult lifespan GO:0008340 15 6 0,000 5,764E-03 0,02708656 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 5,764E-03 0,02703376 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 5,764E-03 0,02698116 ! cerebellar cortex formation GO:0021697 8 6 0,000 5,764E-03 0,02692877 ! catecholamine transport GO:0051937 9 6 0,000 5,764E-03 0,02687658 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 5,764E-03 0,0268246 ! sensory cilium assembly GO:0035058 10 6 0,000 5,764E-03 0,02677281 ! organ or tissue specific immune response GO:0002251 7 6 0,000 5,764E-03 0,02672123 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 5,764E-03 0,02666984 ! maternal placenta development GO:0001893 12 6 0,000 5,764E-03 0,02661865 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 5,764E-03 0,02656766 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 5,764E-03 0,02651686 ! negative regulation of B cell activation GO:0050869 13 6 0,000 5,764E-03 0,02646625 ! protein amino acid prenylation GO:0018346 16 6 0,000 5,764E-03 0,02641584 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 5,764E-03 0,02636562 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 5,764E-03 0,02631559 ! positive regulation of coagulation GO:0050820 12 6 0,000 5,764E-03 0,02626575 ! tRNA transcription GO:0009304 14 7 0,000 6,722E-03 0,03057124 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 6,722E-03 0,03051356 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 6,722E-03 0,03045609 ! behavioral response to cocaine GO:0048148 14 7 0,000 6,722E-03 0,03039885 ! regulation of helicase activity GO:0051095 15 7 0,000 6,722E-03 0,03034181 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 6,722E-03 0,03028499 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 6,722E-03 0,03022839 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 6,722E-03 0,03017199 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 6,722E-03 0,0301158 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 6,722E-03 0,03005983 ! prostate gland development GO:0030850 13 7 0,000 6,722E-03 0,03000406 ! nucleotide-sugar transport GO:0015780 12 7 0,000 6,722E-03 0,02994849 ! synaptonemal complex assembly GO:0007130 10 7 0,000 6,722E-03 0,02989314 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 6,722E-03 0,02983798 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 6,722E-03 0,02978303 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 6,722E-03 0,02972828 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 6,722E-03 0,02967374 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 6,722E-03 0,02961939 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 6,722E-03 0,02956524 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 6,722E-03 0,02951129 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 6,722E-03 0,02945753 ! SMAD protein complex assembly GO:0007183 12 7 0,000 6,722E-03 0,02940397 ! glycolipid transport GO:0046836 10 7 0,000 6,722E-03 0,02935061 ! protein amino acid sulfation GO:0006477 10 7 0,000 6,722E-03 0,02929744 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 6,722E-03 0,02924446 ! neuron adhesion GO:0007158 12 7 0,000 6,722E-03 0,02919167 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 6,722E-03 0,02913907 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 6,722E-03 0,02908667 ! actin-myosin filament sliding GO:0033275 11 7 0,000 6,722E-03 0,02903445 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 6,722E-03 0,02898241 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 6,722E-03 0,02893057 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 6,722E-03 0,0288789 ! mRNA stabilization GO:0048255 18 7 0,000 6,722E-03 0,02882743 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 6,722E-03 0,02877613 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 6,722E-03 0,02872502 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 6,722E-03 0,02867409 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 6,722E-03 0,02862334 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 6,722E-03 0,02857277 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 6,722E-03 0,02852237 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 6,722E-03 0,02847216 ! lipoprotein transport GO:0042953 14 7 0,000 6,722E-03 0,02842212 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 6,722E-03 0,02837226 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 6,722E-03 0,02832257 ! rhythmic behavior GO:0007622 15 7 0,000 6,722E-03 0,02827305 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 6,722E-03 0,02822371 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 6,722E-03 0,02817454 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 6,722E-03 0,02812554 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 6,722E-03 0,02807671 ! regulation of odontogenesis GO:0042481 13 7 0,000 6,722E-03 0,02802805 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 6,722E-03 0,02797956 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 6,722E-03 0,02793124 ! mechanosensory behavior GO:0007638 14 7 0,000 6,722E-03 0,02788308 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 6,722E-03 0,02783509 ! positive regulation of isotype switching GO:0045830 15 7 0,000 6,722E-03 0,02778726 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 6,722E-03 0,0277396 ! protein-cofactor linkage GO:0018065 13 7 0,000 6,722E-03 0,0276921 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 6,722E-03 0,02764476 ! spinal cord patterning GO:0021511 13 7 0,000 6,722E-03 0,02759759 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 6,722E-03 0,02755057 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 6,722E-03 0,02750372 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 6,722E-03 0,02745702 ! adrenal gland development GO:0030325 17 7 0,000 6,722E-03 0,02741049 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 6,722E-03 0,02736411 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 6,722E-03 0,02731788 ! ovulation GO:0030728 9 7 0,000 6,722E-03 0,02727181 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 6,722E-03 0,0272259 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 6,722E-03 0,02718014 ! microtubule nucleation GO:0007020 20 7 0,000 6,722E-03 0,02713454 ! proline biosynthetic process GO:0006561 10 7 0,000 6,722E-03 0,02708909 ! thyroid hormone generation GO:0006590 13 7 0,000 6,722E-03 0,02704379 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 6,722E-03 0,02699864 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 6,722E-03 0,02695364 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 6,722E-03 0,0269088 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 6,722E-03 0,0268641 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 6,722E-03 0,02681955 ! galactose metabolic process GO:0006012 13 7 0,000 6,722E-03 0,02677514 ! vesicle fusion GO:0006906 17 7 0,000 6,722E-03 0,02673089 ! response to dietary excess GO:0002021 8 7 0,000 6,722E-03 0,02668678 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 6,722E-03 0,02664281 ! intracellular pH reduction GO:0051452 11 7 0,000 6,722E-03 0,02659899 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 6,722E-03 0,02655531 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 6,722E-03 0,02651178 ! organ growth GO:0035265 15 7 0,000 6,722E-03 0,02646839 ! purine salvage GO:0043101 10 7 0,000 6,722E-03 0,02642514 ! nucleoside transport GO:0015858 8 7 0,000 6,722E-03 0,02638203 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 6,722E-03 0,02633907 ! parturition GO:0007567 14 7 0,000 6,722E-03 0,02629624 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 6,722E-03 0,02625355 ! rRNA modification GO:0000154 14 7 0,000 6,722E-03 0,026211 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 6,722E-03 0,02616859 ! spindle checkpoint GO:0031577 15 7 0,000 6,722E-03 0,02612631 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 6,722E-03 0,02608417 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 6,722E-03 0,02604217 ! macrophage differentiation GO:0030225 11 7 0,000 6,722E-03 0,0260003 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 6,722E-03 0,02595857 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 6,722E-03 0,02591697 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 6,722E-03 0,0258755 ! hyaluronan metabolic process GO:0030212 8 7 0,000 6,722E-03 0,02583416 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 6,722E-03 0,02579296 ! anterograde axon cargo transport GO:0008089 18 7 0,000 6,722E-03 0,02575189 ! fibrinolysis GO:0042730 10 7 0,000 6,722E-03 0,02571095 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 6,722E-03 0,02567014 ! eating behavior GO:0042755 7 7 0,000 6,722E-03 0,02562946 ! B cell lineage commitment GO:0002326 21 7 0,000 6,722E-03 0,0255889 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 6,722E-03 0,02554848 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 6,722E-03 0,02550818 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 6,722E-03 0,02546801 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 6,722E-03 0,02542797 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 6,722E-03 0,02538805 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 6,722E-03 0,02534825 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 6,722E-03 0,02530859 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 6,722E-03 0,02526904 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 6,722E-03 0,02522962 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 6,722E-03 0,02519032 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 6,722E-03 0,02515114 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 6,722E-03 0,02511209 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 6,722E-03 0,02507316 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 6,722E-03 0,02503434 ! regulation of meiosis GO:0040020 12 7 0,000 6,722E-03 0,02499565 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 6,722E-03 0,02495708 ! T cell lineage commitment GO:0002360 16 7 0,000 6,722E-03 0,02491862 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 6,722E-03 0,02488029 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 6,722E-03 0,02484207 ! oxygen homeostasis GO:0032364 12 7 0,000 6,722E-03 0,02480397 ! transcription termination GO:0006353 13 7 0,000 6,722E-03 0,02476598 ! response to tumor cell GO:0002347 13 7 0,000 6,722E-03 0,02472811 ! regulation of respiratory burst GO:0060263 11 7 0,000 6,722E-03 0,02469036 ! coenzyme A metabolic process GO:0015936 12 7 0,000 6,722E-03 0,02465272 ! anaphase GO:0051322 17 7 0,000 6,722E-03 0,0246152 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 6,722E-03 0,02457779 ! axonal fasciculation GO:0007413 18 7 0,000 6,722E-03 0,02454049 ! negative regulation of nuclear division GO:0051784 14 7 0,000 6,722E-03 0,02450331 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 6,722E-03 0,02446624 ! peptidyl-threonine modification GO:0018210 25 7 0,000 6,722E-03 0,02442928 ! diuresis GO:0030146 12 7 0,000 6,722E-03 0,02439244 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 6,722E-03 0,0243557 ! thiamin metabolic process GO:0006772 7 7 0,000 6,722E-03 0,02431908 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 6,722E-03 0,02428256 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 6,722E-03 0,02424616 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 6,722E-03 0,02420986 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 6,722E-03 0,02417367 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 6,722E-03 0,02413759 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 6,722E-03 0,02410162 ! melanin biosynthetic process GO:0042438 8 7 0,000 6,722E-03 0,02406575 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 6,722E-03 0,02402999 ! dopamine biosynthetic process GO:0042416 18 7 0,000 6,722E-03 0,02399434 ! glycolipid catabolic process GO:0019377 15 7 0,000 6,722E-03 0,02395879 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 6,722E-03 0,02392335 ! lymph node development GO:0048535 10 7 0,000 6,722E-03 0,02388802 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 6,722E-03 0,02385278 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 6,722E-03 0,02381765 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 6,722E-03 0,02378263 ! endosome to lysosome transport GO:0008333 11 7 0,000 6,722E-03 0,0237477 ! protein modification by small protein removal GO:0070646 16 7 0,000 6,722E-03 0,02371288 ! adult feeding behavior GO:0008343 9 7 0,000 6,722E-03 0,02367816 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 6,722E-03 0,02364355 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 6,722E-03 0,02360903 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 6,722E-03 0,02357462 ! muscle adaptation GO:0043500 14 7 0,000 6,722E-03 0,0235403 ! embryonic heart tube development GO:0035050 10 7 0,000 6,722E-03 0,02350608 ! retina homeostasis GO:0001895 12 7 0,000 6,722E-03 0,02347197 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 6,722E-03 0,02343795 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 6,722E-03 0,02340403 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 6,722E-03 0,02337021 ! protein prenylation GO:0018342 18 7 0,000 6,722E-03 0,02333649 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 6,722E-03 0,02330286 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 6,722E-03 0,02326933 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 6,722E-03 0,0232359 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 7,678E-03 0,0265049 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 7,678E-03 0,02646692 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 7,678E-03 0,02642906 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 7,678E-03 0,0263913 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 7,678E-03 0,02635366 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 7,678E-03 0,02631612 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 7,678E-03 0,02627868 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 7,678E-03 0,02624135 ! neutral lipid catabolic process GO:0046461 13 8 0,000 7,678E-03 0,02620413 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 7,678E-03 0,02616702 ! meiotic prophase I GO:0007128 13 8 0,000 7,678E-03 0,02613 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 7,678E-03 0,0260931 ! oligopeptide transport GO:0006857 15 8 0,000 7,678E-03 0,0260563 ! UTP metabolic process GO:0046051 8 8 0,000 7,678E-03 0,0260196 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 7,678E-03 0,025983 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 7,678E-03 0,02594651 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 7,678E-03 0,02591012 ! macrophage chemotaxis GO:0048246 12 8 0,000 7,678E-03 0,02587383 ! succinate metabolic process GO:0006105 14 8 0,000 7,678E-03 0,02583764 ! membrane hyperpolarization GO:0060081 10 8 0,000 7,678E-03 0,02580156 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 7,678E-03 0,02576557 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 7,678E-03 0,02572968 ! T-helper 1 type immune response GO:0042088 12 8 0,000 7,678E-03 0,0256939 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 7,678E-03 0,02565821 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 7,678E-03 0,02562263 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 7,678E-03 0,02558714 ! ganglioside metabolic process GO:0001573 19 8 0,000 7,678E-03 0,02555175 ! reflex GO:0060004 16 8 0,000 7,678E-03 0,02551645 ! negative regulation of endocytosis GO:0045806 11 8 0,000 7,678E-03 0,02548126 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 7,678E-03 0,02544616 ! endothelial cell differentiation GO:0045446 17 8 0,000 7,678E-03 0,02541116 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 7,678E-03 0,02537625 ! glycerolipid catabolic process GO:0046503 13 8 0,000 7,678E-03 0,02534144 ! hemoglobin metabolic process GO:0020027 13 8 0,000 7,678E-03 0,02530673 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 7,678E-03 0,02527211 ! pigment granule organization GO:0048753 16 8 0,000 7,678E-03 0,02523759 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 7,678E-03 0,02520316 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 7,678E-03 0,02516882 ! astrocyte differentiation GO:0048708 18 8 0,000 7,678E-03 0,02513458 ! histidine metabolic process GO:0006547 16 8 0,000 7,678E-03 0,02510043 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 7,678E-03 0,02506637 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 7,678E-03 0,0250324 ! glycine catabolic process GO:0006546 13 8 0,000 7,678E-03 0,02499853 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 7,678E-03 0,02496475 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 7,678E-03 0,02493106 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 7,678E-03 0,02489746 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 7,678E-03 0,02486395 ! regulation of pigmentation during development GO:0048070 24 8 0,000 7,678E-03 0,02483053 ! melanin metabolic process GO:0006582 15 8 0,000 7,678E-03 0,0247972 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 7,678E-03 0,02476396 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 7,678E-03 0,02473081 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 7,678E-03 0,02469775 ! macrophage activation GO:0042116 12 8 0,000 7,678E-03 0,02466477 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 7,678E-03 0,02463188 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 7,678E-03 0,02459909 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 7,678E-03 0,02456637 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 7,678E-03 0,02453375 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 7,678E-03 0,02450121 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 7,678E-03 0,02446876 ! regulation of vascular permeability GO:0043114 12 8 0,000 7,678E-03 0,02443639 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 7,678E-03 0,02440411 ! osteoblast development GO:0002076 16 8 0,000 7,678E-03 0,02437192 ! positive regulation of vasodilation GO:0045909 13 8 0,000 7,678E-03 0,02433981 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 7,678E-03 0,02430778 ! negative regulation of translational initiation GO:0045947 10 8 0,000 7,678E-03 0,02427584 ! Schwann cell differentiation GO:0014037 19 8 0,000 7,678E-03 0,02424398 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 7,678E-03 0,02421221 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 7,678E-03 0,02418051 ! response to UV-B GO:0010224 16 8 0,000 7,678E-03 0,02414891 ! protein targeting to vacuole GO:0006623 12 8 0,000 7,678E-03 0,02411738 ! protein retention in ER lumen GO:0006621 14 8 0,000 7,678E-03 0,02408594 ! intermediate filament organization GO:0045109 12 8 0,000 7,678E-03 0,02405457 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 7,678E-03 0,02402329 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 7,678E-03 0,0239921 ! cellular extravasation GO:0045123 12 8 0,000 7,678E-03 0,02396098 ! cardiac muscle cell development GO:0055013 13 8 0,000 7,678E-03 0,02392994 ! regulation of circadian rhythm GO:0042752 16 8 0,000 7,678E-03 0,02389898 ! response to antibiotic GO:0046677 11 8 0,000 7,678E-03 0,02386811 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 7,678E-03 0,02383731 ! DNA topological change GO:0006265 12 8 0,000 7,678E-03 0,02380659 ! response to tropane GO:0014073 15 8 0,000 7,678E-03 0,02377595 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 7,678E-03 0,02374539 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 7,678E-03 0,02371491 ! melanosome transport GO:0032402 13 8 0,000 7,678E-03 0,0236845 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 7,678E-03 0,02365418 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 7,678E-03 0,02362393 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 7,678E-03 0,02359376 ! mast cell activation GO:0045576 14 8 0,000 7,678E-03 0,02356367 ! multicellular organismal aging GO:0010259 18 8 0,000 7,678E-03 0,02353365 ! dendrite morphogenesis GO:0048813 13 8 0,000 7,678E-03 0,02350371 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 7,678E-03 0,02347384 ! nucleosome disassembly GO:0006337 14 8 0,000 7,678E-03 0,02344405 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 7,678E-03 0,02341434 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 7,678E-03 0,0233847 ! leukocyte activation during immune response GO:0002366 13 8 0,000 7,678E-03 0,02335514 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 7,678E-03 0,02332565 ! establishment of chromosome localization GO:0051303 12 8 0,000 7,678E-03 0,02329623 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 7,678E-03 0,02326689 ! intracellular lipid transport GO:0032365 13 8 0,000 7,678E-03 0,02323763 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 7,678E-03 0,02320843 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 7,678E-03 0,02317931 ! regulation of macrophage activation GO:0043030 15 8 0,000 7,678E-03 0,02315027 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 7,678E-03 0,02312129 ! positive regulation of epidermis development GO:0045684 13 8 0,000 7,678E-03 0,02309239 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 7,678E-03 0,02306356 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 7,678E-03 0,0230348 ! hormone catabolic process GO:0042447 17 8 0,000 7,678E-03 0,02300612 ! positive regulation of glucose import GO:0046326 8 8 0,000 7,678E-03 0,0229775 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 7,678E-03 0,02294896 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 7,678E-03 0,02292049 ! ATP catabolic process GO:0006200 11 8 0,000 7,678E-03 0,02289209 ! blastocyst growth GO:0001832 19 8 0,000 7,678E-03 0,02286375 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 7,678E-03 0,02283549 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 7,678E-03 0,0228073 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 7,678E-03 0,02277918 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 7,678E-03 0,02275112 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 7,678E-03 0,02272314 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 7,678E-03 0,02269523 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 7,678E-03 0,02266738 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 7,678E-03 0,0226396 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 7,678E-03 0,02261189 ! amino sugar catabolic process GO:0046348 10 8 0,000 7,678E-03 0,02258425 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 7,678E-03 0,02255667 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 7,678E-03 0,02252916 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 7,678E-03 0,02250172 ! behavioral response to nicotine GO:0035095 12 8 0,000 7,678E-03 0,02247435 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 7,678E-03 0,02244704 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 7,678E-03 0,0224198 ! NAD biosynthetic process GO:0009435 13 8 0,000 7,678E-03 0,02239262 ! regulation of developmental growth GO:0048638 15 9 0,000 8,634E-03 0,02514952 ! axon extension GO:0048675 15 9 0,000 8,634E-03 0,02511911 ! autophagic vacuole formation GO:0000045 15 9 0,000 8,634E-03 0,02508877 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 8,634E-03 0,0250585 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 8,634E-03 0,02502831 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 8,634E-03 0,0249982 ! pentose-phosphate shunt GO:0006098 16 9 0,000 8,634E-03 0,02496815 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 8,634E-03 0,02493818 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 8,634E-03 0,02490827 ! cell proliferation in forebrain GO:0021846 15 9 0,000 8,634E-03 0,02487844 ! phosphate transport GO:0006817 19 9 0,000 8,634E-03 0,02484868 ! reproductive behavior GO:0019098 19 9 0,000 8,634E-03 0,024819 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 8,634E-03 0,02478938 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 8,634E-03 0,02475983 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 8,634E-03 0,02473036 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 8,634E-03 0,02470095 ! GTP metabolic process GO:0046039 9 9 0,000 8,634E-03 0,02467162 ! RNA methylation GO:0001510 15 9 0,000 8,634E-03 0,02464235 ! elastic fiber assembly GO:0048251 15 9 0,000 8,634E-03 0,02461315 ! induction of positive chemotaxis GO:0050930 15 9 0,000 8,634E-03 0,02458402 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 8,634E-03 0,02455496 ! artery development GO:0060840 24 9 0,000 8,634E-03 0,02452597 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 8,634E-03 0,02449705 ! regulation of glycolysis GO:0006110 21 9 0,000 8,634E-03 0,0244682 ! cerebral cortex cell migration GO:0021795 15 9 0,000 8,634E-03 0,02443941 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 8,634E-03 0,02441069 ! chemosensory behavior GO:0007635 20 9 0,000 8,634E-03 0,02438204 ! microtubule bundle formation GO:0001578 21 9 0,000 8,634E-03 0,02435346 ! middle ear morphogenesis GO:0042474 14 9 0,000 8,634E-03 0,02432494 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 8,634E-03 0,02429649 ! leukocyte degranulation GO:0043299 16 9 0,000 8,634E-03 0,02426811 ! bile acid and bile salt transport GO:0015721 13 9 0,000 8,634E-03 0,02423979 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 8,634E-03 0,02421154 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 8,634E-03 0,02418335 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 8,634E-03 0,02415523 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 8,634E-03 0,02412718 ! protein targeting to ER GO:0045047 22 9 0,000 8,634E-03 0,02409919 ! ceramide biosynthetic process GO:0046513 19 9 0,000 8,634E-03 0,02407126 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 8,634E-03 0,0240434 ! T cell selection GO:0045058 23 9 0,000 8,634E-03 0,02401561 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 8,634E-03 0,02398788 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 8,634E-03 0,02396021 ! phosphagen metabolic process GO:0006599 12 9 0,000 8,634E-03 0,0239326 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 8,634E-03 0,02390506 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 8,634E-03 0,02387759 ! regulation of type I interferon production GO:0032479 12 9 0,000 8,634E-03 0,02385017 ! mannose metabolic process GO:0006013 13 9 0,000 8,634E-03 0,02382282 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 8,634E-03 0,02379553 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 8,634E-03 0,02376831 ! Rac protein signal transduction GO:0016601 17 9 0,000 8,634E-03 0,02374114 ! receptor clustering GO:0043113 18 9 0,000 8,634E-03 0,02371404 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 8,634E-03 0,023687 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 8,634E-03 0,02366002 ! ruffle organization GO:0031529 15 9 0,000 8,634E-03 0,02363311 ! retinol metabolic process GO:0042572 18 9 0,000 8,634E-03 0,02360625 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 8,634E-03 0,02357946 ! behavioral fear response GO:0001662 22 9 0,000 8,634E-03 0,02355272 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 8,634E-03 0,02352605 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 8,634E-03 0,02349943 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 8,634E-03 0,02347288 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 8,634E-03 0,02344639 ! protein heterooligomerization GO:0051291 16 9 0,000 8,634E-03 0,02341996 ! oligodendrocyte development GO:0014003 10 9 0,000 8,634E-03 0,02339358 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 8,634E-03 0,02336727 ! segment specification GO:0007379 13 9 0,000 8,634E-03 0,02334101 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 8,634E-03 0,02331481 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 8,634E-03 0,02328868 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 8,634E-03 0,0232626 ! response to amine stimulus GO:0014075 13 9 0,000 8,634E-03 0,02323658 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 8,634E-03 0,02321061 ! erythrocyte development GO:0048821 15 9 0,000 8,634E-03 0,02318471 ! gas homeostasis GO:0033483 16 9 0,000 8,634E-03 0,02315886 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 8,634E-03 0,02313307 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 8,634E-03 0,02310734 ! renal water homeostasis GO:0003091 14 9 0,000 8,634E-03 0,02308167 ! postreplication repair GO:0006301 22 9 0,000 8,634E-03 0,02305605 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 8,634E-03 0,02303049 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 8,634E-03 0,02300498 ! icosanoid secretion GO:0032309 15 9 0,000 8,634E-03 0,02297954 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 8,634E-03 0,02295414 ! cerebellum morphogenesis GO:0021587 14 9 0,000 8,634E-03 0,02292881 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 8,634E-03 0,02290353 ! regulation of cell division GO:0051302 15 9 0,000 8,634E-03 0,0228783 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 8,634E-03 0,02285314 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 8,634E-03 0,02282802 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 8,634E-03 0,02280296 ! sterol catabolic process GO:0016127 11 9 0,000 8,634E-03 0,02277796 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 8,634E-03 0,02275301 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 8,634E-03 0,02272812 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 8,634E-03 0,02270328 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 8,634E-03 0,02267849 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 8,634E-03 0,02265376 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 8,634E-03 0,02262909 ! musculoskeletal movement GO:0050881 14 9 0,000 8,634E-03 0,02260446 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 8,634E-03 0,02257989 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 8,634E-03 0,02255537 ! regulation of synaptogenesis GO:0051963 15 9 0,000 8,634E-03 0,02253091 ! purine base metabolic process GO:0006144 21 9 0,000 8,634E-03 0,0225065 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 8,634E-03 0,02248214 ! pigment granule transport GO:0051904 17 9 0,000 8,634E-03 0,02245784 ! regulation of fibrinolysis GO:0051917 16 9 0,000 8,634E-03 0,02243359 ! regulation of telomere maintenance GO:0032204 14 9 0,000 8,634E-03 0,02240939 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 8,634E-03 0,02238524 ! regulation of muscle adaptation GO:0043502 14 9 0,000 8,634E-03 0,02236114 ! regulation of amino acid transport GO:0051955 11 9 0,000 8,634E-03 0,0223371 ! mitochondrion localization GO:0051646 15 9 0,000 8,634E-03 0,0223131 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 9,589E-03 0,02475424 ! negative regulation of blood pressure GO:0045776 26 10 0,000 9,589E-03 0,0247277 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 9,589E-03 0,02470123 ! synapsis GO:0007129 13 10 0,000 9,589E-03 0,02467481 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 9,589E-03 0,02464845 ! N-glycan processing GO:0006491 20 10 0,000 9,589E-03 0,02462214 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 9,589E-03 0,02459589 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 9,589E-03 0,0245697 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 9,589E-03 0,02454356 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 9,589E-03 0,02451748 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 9,589E-03 0,02449145 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 9,589E-03 0,02446548 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 9,589E-03 0,02443956 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 9,589E-03 0,0244137 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 9,589E-03 0,02438789 ! androgen metabolic process GO:0008209 17 10 0,000 9,589E-03 0,02436214 ! phospholipid efflux GO:0033700 16 10 0,000 9,589E-03 0,02433644 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 9,589E-03 0,0243108 ! positive regulation of heart contraction GO:0045823 16 10 0,000 9,589E-03 0,02428521 ! lung alveolus development GO:0048286 26 10 0,000 9,589E-03 0,02425967 ! pathogenesis GO:0009405 13 10 0,000 9,589E-03 0,02423419 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 9,589E-03 0,02420876 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 9,589E-03 0,02418338 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 9,589E-03 0,02415806 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 9,589E-03 0,02413279 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 9,589E-03 0,02410757 ! endoderm development GO:0007492 16 10 0,000 9,589E-03 0,02408241 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 9,589E-03 0,0240573 ! arginine catabolic process GO:0006527 13 10 0,000 9,589E-03 0,02403224 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 9,589E-03 0,02400723 ! proline metabolic process GO:0006560 13 10 0,000 9,589E-03 0,02398227 ! glucan biosynthetic process GO:0009250 14 10 0,000 9,589E-03 0,02395737 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 9,589E-03 0,02393252 ! polyamine biosynthetic process GO:0006596 12 10 0,000 9,589E-03 0,02390772 ! V(D)J recombination GO:0033151 28 10 0,000 9,589E-03 0,02388297 ! reverse cholesterol transport GO:0043691 16 10 0,000 9,589E-03 0,02385827 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 9,589E-03 0,02383362 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 18 10 0,000 9,589E-03 0,02380903 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 9,589E-03 0,02378448 ! regulation of sodium ion transport GO:0002028 21 10 0,000 9,589E-03 0,02375999 ! multicellular organism growth GO:0035264 18 10 0,000 9,589E-03 0,02373554 ! phagocytosis, engulfment GO:0006911 28 10 0,000 9,589E-03 0,02371115 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 9,589E-03 0,02368681 ! epithelial cell development GO:0002064 20 10 0,000 9,589E-03 0,02366251 ! lens development in camera-type eye GO:0002088 16 10 0,000 9,589E-03 0,02363827 ! retinoic acid metabolic process GO:0042573 14 10 0,000 9,589E-03 0,02361407 ! macroautophagy GO:0016236 17 10 0,000 9,589E-03 0,02358993 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 9,589E-03 0,02356583 ! positive regulation of translational initiation GO:0045948 11 10 0,000 9,589E-03 0,02354178 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 9,589E-03 0,02351779 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 9,589E-03 0,02349384 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 9,589E-03 0,02346994 ! copper ion homeostasis GO:0055070 13 10 0,000 9,589E-03 0,02344609 ! regulation of bone resorption GO:0045124 25 10 0,000 9,589E-03 0,02342228 ! regulation of gliogenesis GO:0014013 23 10 0,000 9,589E-03 0,02339853 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 9,589E-03 0,02337482 ! alpha-beta T cell activation GO:0046631 23 10 0,000 9,589E-03 0,02335116 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 9,589E-03 0,02332755 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 9,589E-03 0,02330399 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 9,589E-03 0,02328047 ! blastoderm segmentation GO:0007350 18 10 0,000 9,589E-03 0,023257 ! response to dsRNA GO:0043331 20 10 0,000 9,589E-03 0,02323358 ! DNA ligation GO:0006266 19 10 0,000 9,589E-03 0,02321021 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 9,589E-03 0,02318688 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 9,589E-03 0,0231636 ! melanosome localization GO:0032400 16 10 0,000 9,589E-03 0,02314037 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 9,589E-03 0,02311718 ! regulation of B cell differentiation GO:0045577 19 10 0,000 9,589E-03 0,02309404 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 9,589E-03 0,02307095 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 9,589E-03 0,0230479 ! mRNA cleavage GO:0006379 17 10 0,000 9,589E-03 0,0230249 ! protein sumoylation GO:0016925 15 10 0,000 9,589E-03 0,02300194 ! hindbrain morphogenesis GO:0021575 19 10 0,000 9,589E-03 0,02297903 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 9,589E-03 0,02295617 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 9,589E-03 0,02293335 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 9,589E-03 0,02291057 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 9,589E-03 0,02288785 ! salivary gland development GO:0007431 27 10 0,000 9,589E-03 0,02286516 ! prophase GO:0051324 15 10 0,000 9,589E-03 0,02284252 ! negative regulation of neurological system process GO:0031645 19 10 0,000 9,589E-03 0,02281993 ! apical protein localization GO:0045176 15 10 0,000 9,589E-03 0,02279738 ! ubiquinone metabolic process GO:0006743 15 10 0,000 9,589E-03 0,02277487 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 9,589E-03 0,02275241 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 9,589E-03 0,02273 ! midbrain development GO:0030901 13 10 0,000 9,589E-03 0,02270763 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 9,589E-03 0,0226853 ! methionine biosynthetic process GO:0009086 19 10 0,000 9,589E-03 0,02266301 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 9,589E-03 0,02264077 ! quaternary ammonium group transport GO:0015697 21 10 0,000 9,589E-03 0,02261858 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 9,589E-03 0,02259642 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 9,589E-03 0,02257431 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 9,589E-03 0,02255225 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 9,589E-03 0,02253022 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 9,589E-03 0,02250824 ! oocyte development GO:0048599 17 10 0,000 9,589E-03 0,0224863 ! establishment of pigment granule localization GO:0051905 18 10 0,000 9,589E-03 0,02246441 ! blastocyst formation GO:0001825 17 10 0,000 9,589E-03 0,02244256 ! cerebellar cortex development GO:0021695 15 10 0,000 9,589E-03 0,02242075 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 9,589E-03 0,02239898 ! activation of innate immune response GO:0002218 12 10 0,000 9,589E-03 0,02237725 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 9,589E-03 0,02235557 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 9,589E-03 0,02233393 ! response to nicotine GO:0035094 20 10 0,000 9,589E-03 0,02231233 ! establishment of cell polarity GO:0030010 16 10 0,000 9,589E-03 0,02229077 ! negative regulation of immune effector process GO:0002698 20 10 0,000 9,589E-03 0,02226926 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 9,589E-03 0,02224778 ! localization within membrane GO:0051668 20 10 0,000 9,589E-03 0,02222635 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01054292 0,02441411 ! respiratory burst GO:0045730 17 11 0,000 0,01054292 0,02439063 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01054292 0,0243672 ! neuron fate specification GO:0048665 17 11 0,000 0,01054292 0,02434382 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01054292 0,02432048 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01054292 0,02429718 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01054292 0,02427393 ! thyroid gland development GO:0030878 26 11 0,000 0,01054292 0,02425073 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01054292 0,02422756 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01054292 0,02420445 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01054292 0,02418137 ! response to pain GO:0048265 24 11 0,000 0,01054292 0,02415834 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01054292 0,02413536 ! T cell proliferation GO:0042098 26 11 0,000 0,01054292 0,02411241 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01054292 0,02408952 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01054292 0,02406666 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01054292 0,02404385 ! bone resorption GO:0045453 16 11 0,000 0,01054292 0,02402108 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01054292 0,02399835 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01054292 0,02397567 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01054292 0,02395303 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01054292 0,02393043 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01054292 0,02390788 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01054292 0,02388537 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01054292 0,0238629 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01054292 0,02384047 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01054292 0,02381808 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01054292 0,02379574 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01054292 0,02377344 ! lipid digestion GO:0044241 18 11 0,000 0,01054292 0,02375118 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01054292 0,02372896 ! adult heart development GO:0007512 14 11 0,000 0,01054292 0,02370678 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01054292 0,02368465 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01054292 0,02366256 ! temperature homeostasis GO:0001659 17 11 0,000 0,01054292 0,0236405 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01054292 0,02361849 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01054292 0,02359652 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01054292 0,02357459 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01054292 0,0235527 ! regulation of organ growth GO:0046620 13 11 0,000 0,01054292 0,02353085 ! pigment granule localization GO:0051875 20 11 0,000 0,01054292 0,02350905 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01054292 0,02348728 ! vasoconstriction GO:0042310 18 11 0,000 0,01054292 0,02346555 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01054292 0,02344386 ! embryonic axis specification GO:0000578 18 11 0,000 0,01054292 0,02342222 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01054292 0,02340061 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01054292 0,02337904 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01054292 0,02335751 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01054292 0,02333603 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01054292 0,02331458 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01054292 0,02329317 ! zymogen activation GO:0031638 15 11 0,000 0,01054292 0,0232718 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01054292 0,02325047 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01054292 0,02322918 ! nucleosome positioning GO:0016584 15 11 0,000 0,01054292 0,02320792 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01054292 0,02318671 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01054292 0,02316553 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01054292 0,0231444 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01054292 0,0231233 ! acid secretion GO:0046717 18 11 0,000 0,01054292 0,02310224 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01054292 0,02308122 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01054292 0,02306024 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01054292 0,02303929 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01054292 0,02301838 ! oocyte differentiation GO:0009994 18 11 0,000 0,01054292 0,02299752 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01054292 0,02297668 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01054292 0,02295589 ! cholesterol efflux GO:0033344 19 11 0,000 0,01054292 0,02293514 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01054292 0,02291442 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01054292 0,02289374 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01054292 0,02287309 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01054292 0,02285249 ! embryonic gut development GO:0048566 15 11 0,000 0,01054292 0,02283192 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01054292 0,02281138 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01054292 0,02279089 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01054292 0,02277043 ! defense response to fungus GO:0050832 13 11 0,000 0,01054292 0,02275001 ! developmental induction GO:0031128 19 11 0,000 0,01054292 0,02272962 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01054292 0,02270927 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01054292 0,02268896 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01054292 0,02266869 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01054292 0,02264845 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01054292 0,02262824 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01054292 0,02260807 ! nucleus localization GO:0051647 19 11 0,000 0,01054292 0,02258794 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01054292 0,02256785 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01149603 0,02458617 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01149603 0,02456433 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01149603 0,02454253 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01149603 0,02452078 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01149603 0,02449906 ! virus-host interaction GO:0019048 29 12 0,000 0,01149603 0,02447738 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01149603 0,02445574 ! cartilage condensation GO:0001502 20 12 0,000 0,01149603 0,02443413 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01149603 0,02441257 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01149603 0,02439104 ! protein complex disassembly GO:0043241 27 12 0,000 0,01149603 0,02436955 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01149603 0,0243481 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01149603 0,02432668 ! hippocampus development GO:0021766 26 12 0,000 0,01149603 0,0243053 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,01149603 0,02428397 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01149603 0,02426266 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01149603 0,0242414 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01149603 0,02422017 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01149603 0,02419898 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01149603 0,02417783 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01149603 0,02415671 ! drug transport GO:0015893 16 12 0,000 0,01149603 0,02413563 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01149603 0,02411459 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01149603 0,02409359 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01149603 0,02407262 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01149603 0,02405168 ! focal adhesion formation GO:0048041 35 12 0,000 0,01149603 0,02403079 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01149603 0,02400993 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01149603 0,0239891 ! forebrain cell migration GO:0021885 21 12 0,000 0,01149603 0,02396832 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01149603 0,02394756 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01149603 0,02392685 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01149603 0,02390617 ! entry into host cell GO:0030260 32 12 0,000 0,01149603 0,02388552 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01149603 0,02386491 ! monoamine transport GO:0015844 18 12 0,000 0,01149603 0,02384434 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01149603 0,0238238 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01149603 0,0238033 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01149603 0,02378283 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01149603 0,0237624 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01149603 0,02374201 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01149603 0,02372164 ! protein homotetramerization GO:0051289 21 12 0,000 0,01149603 0,02370132 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01149603 0,02368102 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01149603 0,02366077 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01149603 0,02364054 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01149603 0,02362036 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01149603 0,0236002 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01149603 0,02358008 ! cranial nerve development GO:0021545 20 12 0,000 0,01149603 0,02356 ! fucose catabolic process GO:0019317 22 12 0,000 0,01149603 0,02353995 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01149603 0,02351993 ! histone acetylation GO:0016573 26 12 0,000 0,01149603 0,02349995 ! histone methylation GO:0016571 26 12 0,000 0,01149603 0,02348 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01149603 0,02346008 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01149603 0,0234402 ! gland morphogenesis GO:0022612 29 12 0,000 0,01149603 0,02342035 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01149603 0,02340054 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01149603 0,02338076 ! T cell homeostasis GO:0043029 25 12 0,000 0,01149603 0,02336101 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01149603 0,0233413 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01149603 0,02332162 ! spleen development GO:0048536 22 12 0,000 0,01149603 0,02330197 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01149603 0,02328235 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01149603 0,02326277 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01149603 0,02324322 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01149603 0,02322371 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01149603 0,02320423 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01149603 0,02318477 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01149603 0,02316536 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01149603 0,02314597 ! response to cold GO:0009409 17 12 0,000 0,01149603 0,02312662 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01149603 0,0231073 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01149603 0,02308801 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01244825 0,02497955 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01244825 0,02495873 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01244825 0,02493795 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01244825 0,0249172 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01244825 0,02489649 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01244825 0,02487581 ! lipid localization GO:0010876 28 13 0,000 0,01244825 0,02485517 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01244825 0,02483456 ! organelle fusion GO:0048284 32 13 0,000 0,01244825 0,02481399 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01244825 0,02479344 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01244825 0,02477294 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01244825 0,02475246 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01244825 0,02473202 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01244825 0,02471162 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01244825 0,02469125 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01244825 0,02467091 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01244825 0,0246506 ! methionine metabolic process GO:0006555 27 13 0,000 0,01244825 0,02463033 ! plasma membrane organization GO:0007009 24 13 0,000 0,01244825 0,02461009 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01244825 0,02458989 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01244825 0,02456971 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01244825 0,02454957 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01244825 0,02452947 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01244825 0,02450939 ! response to X-ray GO:0010165 25 13 0,000 0,01244825 0,02448935 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01244825 0,02446935 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01244825 0,02444937 ! exocrine system development GO:0035272 32 13 0,000 0,01244825 0,02442943 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01244825 0,02440952 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01244825 0,02438964 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01244825 0,0243698 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01244825 0,02434998 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01244825 0,0243302 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01244825 0,02431045 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01244825 0,02429074 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01244825 0,02427105 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01244825 0,0242514 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01244825 0,02423178 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01244825 0,02421219 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01244825 0,02419263 ! ribosome assembly GO:0042255 17 13 0,000 0,01244825 0,02417311 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01244825 0,02415361 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01244825 0,02413415 ! chromatin silencing GO:0006342 26 13 0,000 0,01244825 0,02411472 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01244825 0,02409532 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01244825 0,02407595 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01244825 0,02405661 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01244825 0,0240373 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01244825 0,02401803 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01244825 0,02399878 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01244825 0,02397957 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01244825 0,02396038 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01244825 0,02394123 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01244825 0,02392211 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01244825 0,02390302 ! embryonic placenta development GO:0001892 23 13 0,000 0,01244825 0,02388396 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01244825 0,02386492 ! insulin secretion GO:0030073 23 13 0,000 0,01244825 0,02384592 ! actin filament polymerization GO:0030041 24 13 0,000 0,01244825 0,02382695 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01244825 0,02380801 ! acrosome reaction GO:0007340 18 13 0,000 0,01244825 0,0237891 ! rRNA transcription GO:0009303 25 14 0,000 0,01339958 0,02558682 ! lactation GO:0007595 26 14 0,000 0,01339958 0,02556653 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01339958 0,02554627 ! reproductive cellular process GO:0048610 20 14 0,000 0,01339958 0,02552604 ! tRNA modification GO:0006400 20 14 0,000 0,01339958 0,02550585 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01339958 0,02548569 ! regulation of S phase GO:0033261 23 14 0,000 0,01339958 0,02546556 ! water transport GO:0006833 21 14 0,000 0,01339958 0,02544546 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01339958 0,02542539 ! non-recombinational repair GO:0000726 25 14 0,000 0,01339958 0,02540535 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01339958 0,02538535 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01339958 0,02536538 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01339958 0,02534543 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01339958 0,02532552 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01339958 0,02530565 ! palate development GO:0060021 31 14 0,000 0,01339958 0,0252858 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01339958 0,02526598 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01339958 0,0252462 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01339958 0,02522644 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01339958 0,02520672 ! arginine metabolic process GO:0006525 17 14 0,000 0,01339958 0,02518703 ! regulation of heart rate GO:0002027 24 14 0,000 0,01339958 0,02516736 ! organic alcohol transport GO:0015850 29 14 0,000 0,01339958 0,02514773 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01339958 0,02512813 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01339958 0,02510856 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01339958 0,02508902 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01339958 0,02506951 ! L-amino acid transport GO:0015807 30 14 0,000 0,01339958 0,02505003 ! bone mineralization GO:0030282 17 14 0,000 0,01339958 0,02503058 ! stem cell development GO:0048864 43 14 0,000 0,01339958 0,02501117 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01339958 0,02499178 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01339958 0,02497242 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01339958 0,02495309 ! cerebellum development GO:0021549 21 14 0,000 0,01339958 0,02493379 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01339958 0,02491452 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01339958 0,02489528 ! response to gamma radiation GO:0010332 28 14 0,000 0,01339958 0,02487608 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01339958 0,0248569 ! cofactor transport GO:0051181 26 14 0,000 0,01339958 0,02483775 ! NADP metabolic process GO:0006739 24 14 0,000 0,01339958 0,02481862 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01339958 0,02479953 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01339958 0,02478047 ! intestinal absorption GO:0050892 25 14 0,000 0,01339958 0,02476144 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01339958 0,02474244 ! oxygen transport GO:0015671 21 14 0,000 0,01339958 0,02472346 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01339958 0,02470452 ! male genitalia development GO:0030539 24 14 0,000 0,01339958 0,0246856 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01339958 0,02466671 ! regulation of axon extension GO:0030516 37 14 0,000 0,01339958 0,02464785 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01339958 0,02462902 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01435003 0,02635586 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01435003 0,02633576 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,01435003 0,02631568 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01435003 0,02629564 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01435003 0,02627563 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01435003 0,02625565 ! copper ion transport GO:0006825 20 15 0,000 0,01435003 0,0262357 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01435003 0,02621578 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01435003 0,02619589 ! sulfate transport GO:0008272 23 15 0,000 0,01435003 0,02617603 ! response to cAMP GO:0051591 22 15 0,000 0,01435003 0,02615619 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01435003 0,02613639 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01435003 0,02611662 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01435003 0,02609688 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01435003 0,02607717 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01435003 0,02605749 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01435003 0,02603784 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01435003 0,02601822 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01435003 0,02599863 ! pituitary gland development GO:0021983 29 15 0,000 0,01435003 0,02597906 ! vesicle coating GO:0006901 33 15 0,000 0,01435003 0,02595953 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01435003 0,02594003 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01435003 0,02592055 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01435003 0,02590111 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01435003 0,02588169 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01435003 0,02586231 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01435003 0,02584295 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01435003 0,02582362 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01435003 0,02580432 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01435003 0,02578505 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01435003 0,0257658 ! histone deacetylation GO:0016575 20 15 0,000 0,01435003 0,02574659 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01435003 0,0257274 ! tissue regeneration GO:0042246 26 15 0,000 0,01435003 0,02570825 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01435003 0,02568912 ! water homeostasis GO:0030104 27 15 0,000 0,01435003 0,02567002 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01435003 0,02565095 ! muscle maintenance GO:0046716 26 15 0,000 0,01435003 0,02563191 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01435003 0,02561289 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01435003 0,0255939 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01435003 0,02557495 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01435003 0,02555602 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01435003 0,02553711 ! cell killing GO:0001906 29 15 0,000 0,01435003 0,02551824 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,01435003 0,02549939 ! detection of bacterium GO:0016045 18 15 0,000 0,01435003 0,02548057 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01435003 0,02546178 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01435003 0,02544302 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01435003 0,02542428 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01435003 0,02540558 ! peptide hormone processing GO:0016486 23 15 0,000 0,01435003 0,0253869 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,0152996 0,0270469 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,0152996 0,02702704 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,0152996 0,02700722 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,0152996 0,02698742 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,0152996 0,02696764 ! bone remodeling GO:0046849 27 16 0,000 0,0152996 0,0269479 ! filopodium assembly GO:0046847 32 16 0,000 0,0152996 0,02692819 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,0152996 0,0269085 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,0152996 0,02688885 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,0152996 0,02686922 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,0152996 0,02684962 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,0152996 0,02683005 ! startle response GO:0001964 28 16 0,000 0,0152996 0,02681051 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,0152996 0,026791 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,0152996 0,02677152 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,0152996 0,02675206 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,0152996 0,02673263 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,0152996 0,02671323 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,0152996 0,02669386 ! protein polyubiquitination GO:0000209 34 16 0,000 0,0152996 0,02667452 ! glutamate metabolic process GO:0006536 22 16 0,000 0,0152996 0,0266552 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,0152996 0,02663591 ! response to osmotic stress GO:0006970 25 16 0,000 0,0152996 0,02661666 ! lysosomal transport GO:0007041 26 16 0,000 0,0152996 0,02659742 ! fructose metabolic process GO:0006000 25 16 0,000 0,0152996 0,02657822 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,0152996 0,02655904 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,0152996 0,02653989 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,0152996 0,02652077 ! negative regulation of immune response GO:0050777 35 16 0,000 0,0152996 0,02650168 ! axon cargo transport GO:0008088 43 16 0,000 0,0152996 0,02648261 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,0152996 0,02646358 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,0152996 0,02644456 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,0152996 0,02642558 ! DNA replication initiation GO:0006270 27 16 0,000 0,0152996 0,02640662 ! neuron recognition GO:0008038 35 16 0,000 0,0152996 0,02638769 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,0152996 0,02636879 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,0152996 0,02634992 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,0152996 0,02633107 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,0152996 0,02631225 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,0152996 0,02629345 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,0152996 0,02627469 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,0152996 0,02625594 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,0152996 0,02623723 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,0152996 0,02621854 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,0152996 0,02619988 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,0152996 0,02618125 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,0152996 0,02616264 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,0152996 0,02614406 ! defense response to virus GO:0051607 37 16 0,000 0,0152996 0,0261255 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,01624828 0,02772579 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,01624828 0,02770614 ! metencephalon development GO:0022037 30 17 0,000 0,01624828 0,02768652 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,01624828 0,02766693 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,01624828 0,02764736 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,01624828 0,02762782 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,01624828 0,02760831 ! signal complex assembly GO:0007172 41 17 0,000 0,01624828 0,02758883 ! endothelial cell migration GO:0043542 28 17 0,000 0,01624828 0,02756937 ! inositol metabolic process GO:0006020 28 17 0,000 0,01624828 0,02754994 ! gene silencing by RNA GO:0031047 36 17 0,000 0,01624828 0,02753054 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,01624828 0,02751117 ! glial cell development GO:0021782 27 17 0,000 0,01624828 0,02749182 ! limbic system development GO:0021761 36 17 0,000 0,01624828 0,0274725 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,01624828 0,02745321 ! adult walking behavior GO:0007628 33 17 0,000 0,01624828 0,02743394 ! heart looping GO:0001947 30 17 0,000 0,01624828 0,0274147 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,01624828 0,02739549 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,01624828 0,02737631 ! myoblast differentiation GO:0045445 45 17 0,000 0,01624828 0,02735715 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,01624828 0,02733802 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,01624828 0,02731891 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,01624828 0,02729984 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,01624828 0,02728079 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01624828 0,02726176 ! glycine metabolic process GO:0006544 28 17 0,000 0,01624828 0,02724276 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,01624828 0,02722379 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01624828 0,02720485 ! NAD metabolic process GO:0019674 29 17 0,000 0,01624828 0,02718593 ! membrane budding GO:0006900 37 17 0,000 0,01624828 0,02716704 ! DNA integration GO:0015074 29 17 0,000 0,01624828 0,02714817 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,01624828 0,02712933 ! regulation of protein binding GO:0043393 33 17 0,000 0,01624828 0,02711052 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,01624828 0,02709173 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,01624828 0,02707297 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,01624828 0,02705423 ! genitalia development GO:0048806 30 17 0,000 0,01624828 0,02703552 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,01624828 0,02701684 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,01624828 0,02699818 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,01624828 0,02697955 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,01624828 0,02696094 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,01624828 0,02694236 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,01624828 0,02692381 ! steroid catabolic process GO:0006706 31 17 0,000 0,01624828 0,02690528 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,01624828 0,02688677 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,01624828 0,02686829 ! gas transport GO:0015669 25 17 0,000 0,01624828 0,02684984 ! organic cation transport GO:0015695 31 17 0,000 0,01624828 0,02683141 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,01624828 0,02681301 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,01624828 0,02679463 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,01624828 0,02677628 ! microspike assembly GO:0030035 36 17 0,000 0,01624828 0,02675795 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,01624828 0,02673965 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,01719608 0,02828009 ! neuron maturation GO:0042551 42 18 0,000 0,01719608 0,02826077 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,01719608 0,02824148 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,01719608 0,02822222 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,01719608 0,02820298 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,01719608 0,02818377 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,01719608 0,02816458 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,01719608 0,02814542 ! memory GO:0007613 31 18 0,000 0,01719608 0,02812629 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01719608 0,02810718 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,01719608 0,0280881 ! patterning of blood vessels GO:0001569 39 18 0,000 0,01719608 0,02806905 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,01719608 0,02805002 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,01719608 0,02803101 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,01719608 0,02801203 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,01719608 0,02799308 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01719608 0,02797415 ! response to retinoic acid GO:0032526 26 18 0,000 0,01719608 0,02795525 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,01719608 0,02793638 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,01719608 0,02791753 ! response to fungus GO:0009620 21 18 0,000 0,01719608 0,0278987 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,01719608 0,0278799 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,01719608 0,02786113 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,01719608 0,02784238 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,01719608 0,02782365 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,01719608 0,02780496 ! vitamin transport GO:0051180 27 18 0,000 0,01719608 0,02778628 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,01719608 0,02776763 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,01719608 0,02774901 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,01719608 0,02773041 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,01719608 0,02771184 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,01719608 0,02769329 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,01719608 0,02767477 ! nerve development GO:0021675 28 18 0,000 0,01719608 0,02765627 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,01719608 0,02763779 ! protein secretion GO:0009306 39 19 0,000 0,018143 0,02914023 ! positive regulation of translation GO:0045727 30 19 0,000 0,018143 0,02912079 ! negative regulation of defense response GO:0031348 25 19 0,000 0,018143 0,02910137 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,018143 0,02908199 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,018143 0,02906262 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,018143 0,02904329 ! lipid phosphorylation GO:0046834 35 19 0,000 0,018143 0,02902398 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,018143 0,02900469 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,018143 0,02898543 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,018143 0,0289662 ! bile acid metabolic process GO:0008206 29 19 0,000 0,018143 0,02894699 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,018143 0,02892781 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,018143 0,02890865 ! cerebral cortex development GO:0021987 36 19 0,000 0,018143 0,02888952 ! pigmentation during development GO:0048066 41 19 0,000 0,018143 0,02887041 ! response to vitamin A GO:0033189 27 19 0,000 0,018143 0,02885133 ! heme metabolic process GO:0042168 36 19 0,000 0,018143 0,02883227 ! actin filament bundle formation GO:0051017 42 19 0,000 0,018143 0,02881324 ! neuromuscular junction development GO:0007528 34 19 0,000 0,018143 0,02879424 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,018143 0,02877525 ! plasma membrane fusion GO:0045026 28 19 0,000 0,018143 0,0287563 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,018143 0,02873737 ! peptide cross-linking GO:0018149 37 19 0,000 0,018143 0,02871846 ! protein export from nucleus GO:0006611 36 19 0,000 0,018143 0,02869958 ! heart process GO:0003015 30 19 0,000 0,018143 0,02868072 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,018143 0,02866189 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,018143 0,02864308 ! visual learning GO:0008542 36 19 0,000 0,018143 0,0286243 ! cellular pigmentation GO:0033059 36 19 0,000 0,018143 0,02860554 ! G1 phase GO:0051318 40 19 0,000 0,018143 0,02858681 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,018143 0,0285681 ! cell-cell junction organization GO:0045216 35 19 0,000 0,018143 0,02854942 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,018143 0,02853076 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,018143 0,02851212 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,018143 0,02849351 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,018143 0,02847493 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,018143 0,02845636 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,018143 0,02843782 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,018143 0,02841931 ! cilium assembly GO:0042384 37 19 0,000 0,018143 0,02840082 ! peptide hormone secretion GO:0030072 31 19 0,000 0,018143 0,02838235 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,01908904 0,0298429 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,01908904 0,02982353 ! positive regulation of ossification GO:0045778 47 20 0,000 0,01908904 0,02980417 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,01908904 0,02978484 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,01908904 0,02976554 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,01908904 0,02974626 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,01908904 0,02972701 ! cAMP metabolic process GO:0046058 36 20 0,000 0,01908904 0,02970778 ! response to vitamin GO:0033273 31 20 0,000 0,01908904 0,02968858 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,01908904 0,0296694 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,01908904 0,02965024 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,01908904 0,02963112 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,01908904 0,02961201 ! response to alkaloid GO:0043279 38 20 0,000 0,01908904 0,02959293 ! retinoid metabolic process GO:0001523 32 20 0,000 0,01908904 0,02957388 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,01908904 0,02955484 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,01908904 0,02953584 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,01908904 0,02951686 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,01908904 0,0294979 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,01908904 0,02947897 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,01908904 0,02946006 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,01908904 0,02944117 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,01908904 0,02942231 ! body fluid secretion GO:0007589 31 20 0,000 0,01908904 0,02940348 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,01908904 0,02938466 ! peptide secretion GO:0002790 35 20 0,000 0,01908904 0,02936588 ! stem cell differentiation GO:0048863 53 20 0,000 0,01908904 0,02934711 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,01908904 0,02932837 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,01908904 0,02930965 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,01908904 0,02929096 ! sensory perception of pain GO:0019233 30 20 0,000 0,01908904 0,02927229 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,01908904 0,02925365 ! diencephalon development GO:0021536 34 20 0,000 0,01908904 0,02923503 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,01908904 0,02921643 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,01908904 0,02919786 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,01908904 0,02917931 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,01908904 0,02916078 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,01908904 0,02914228 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,01908904 0,0291238 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,01908904 0,02910534 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,01908904 0,02908691 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,01908904 0,0290685 ! regulation of glucose import GO:0046324 29 20 0,000 0,01908904 0,02905011 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,01908904 0,02903175 ! actin filament-based movement GO:0030048 43 20 0,000 0,01908904 0,02901341 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,01908904 0,02899509 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,01908904 0,0289768 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,01908904 0,02895853 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,01908904 0,02894028 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,01908904 0,02892206 ! regulation of cell killing GO:0031341 42 21 0,000 0,0200342 0,03033498 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,0200342 0,0303159 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,0200342 0,03029684 ! hormone secretion GO:0046879 38 21 0,000 0,0200342 0,03027781 ! glycerol metabolic process GO:0006071 34 21 0,000 0,0200342 0,03025881 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,0200342 0,03023982 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,0200342 0,03022086 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,0200342 0,03020193 ! axis specification GO:0009798 38 21 0,000 0,0200342 0,03018302 ! ovarian follicle development GO:0001541 35 21 0,000 0,0200342 0,03016413 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,0200342 0,03014526 ! smooth muscle contraction GO:0006939 46 21 0,000 0,0200342 0,03012642 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,0200342 0,03010761 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,0200342 0,03008881 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,0200342 0,03007004 ! cell aging GO:0007569 44 21 0,000 0,0200342 0,0300513 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,0200342 0,03003257 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,0200342 0,03001387 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,0200342 0,0299952 ! cytolysis GO:0019835 24 21 0,000 0,0200342 0,02997654 ! vasodilation GO:0042311 39 21 0,000 0,0200342 0,02995791 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,0200342 0,0299393 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,0200342 0,02992072 ! oogenesis GO:0048477 36 21 0,000 0,0200342 0,02990216 ! DNA modification GO:0006304 34 21 0,000 0,0200342 0,02988362 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,0200342 0,0298651 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,0200342 0,02984661 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,0200342 0,02982814 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,0200342 0,0298097 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,0200342 0,02979127 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,0200342 0,02977287 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,0200342 0,02975449 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,0200342 0,02973614 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,0200342 0,0297178 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,0200342 0,02969949 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,0200342 0,02968121 ! collagen catabolic process GO:0030574 28 21 0,000 0,0200342 0,02966294 ! sperm-egg recognition GO:0035036 21 21 0,000 0,0200342 0,0296447 ! gut development GO:0048565 39 21 0,000 0,0200342 0,02962648 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,02097848 0,03100382 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,02097848 0,03098478 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,02097848 0,03096577 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,02097848 0,03094679 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,02097848 0,03092783 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,02097848 0,03090889 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,02097848 0,03088997 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,02097848 0,03087108 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,02097848 0,03085221 ! regeneration GO:0031099 41 22 0,000 0,02097848 0,03083336 ! keratinization GO:0031424 28 22 0,000 0,02097848 0,03081454 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,02097848 0,03079574 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,02097848 0,03077696 ! sensory perception of taste GO:0050909 28 22 0,000 0,02097848 0,0307582 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,02097848 0,03073947 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,02097848 0,03072076 ! vacuolar transport GO:0007034 36 22 0,000 0,02097848 0,03070208 ! lysosome organization GO:0007040 41 22 0,000 0,02097848 0,03068341 ! central nervous system neuron development GO:0021954 46 22 0,000 0,02097848 0,03066477 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,02097848 0,03064615 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,02097848 0,03062756 ! fucose metabolic process GO:0006004 39 22 0,000 0,02097848 0,03060898 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,02097848 0,03059043 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,02097848 0,0305719 ! ureteric bud development GO:0001657 43 22 0,000 0,02097848 0,0305534 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,02097848 0,03053491 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,02097848 0,03051645 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,02097848 0,03049801 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,02097848 0,0304796 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,02097848 0,0304612 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,02097848 0,03044283 ! sarcomere organization GO:0045214 30 22 0,000 0,02097848 0,03042448 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,02097848 0,03040615 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,02097848 0,03038785 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,02097848 0,03036956 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,02097848 0,0303513 ! protein stabilization GO:0050821 39 22 0,000 0,02097848 0,03033306 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,02192188 0,0316781 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,02192188 0,03165908 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,02192188 0,03164009 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,02192188 0,03162112 ! gluconeogenesis GO:0006094 33 23 0,000 0,02192188 0,03160218 ! viral genome replication GO:0019079 41 23 0,000 0,02192188 0,03158325 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,02192188 0,03156435 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,02192188 0,03154547 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,02192188 0,03152662 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,02192188 0,03150779 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,02192188 0,03148898 ! visual behavior GO:0007632 42 23 0,000 0,02192188 0,03147019 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,02192188 0,03145142 ! response to ethanol GO:0045471 46 23 0,000 0,02192188 0,03143268 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,02192188 0,03141396 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,02192188 0,03139526 ! peroxisome organization GO:0007031 37 23 0,000 0,02192188 0,03137658 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,02192188 0,03135793 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,02192188 0,03133929 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,02192188 0,03132068 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,02192188 0,0313021 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,02192188 0,03128353 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,02192188 0,03126499 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,02192188 0,03124647 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,02192188 0,03122797 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,02192188 0,03120949 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,02192188 0,03119103 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,02192188 0,0311726 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,02192188 0,03115418 ! fatty acid transport GO:0015908 44 23 0,000 0,02192188 0,03113579 ! platelet activation GO:0030168 37 23 0,000 0,02192188 0,03111742 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,02192188 0,03109908 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,02192188 0,03108075 ! hormone transport GO:0009914 40 23 0,000 0,02192188 0,03106245 ! cell-cell recognition GO:0009988 25 23 0,000 0,02192188 0,03104416 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,02192188 0,0310259 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,02192188 0,03100766 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,02192188 0,03098944 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,02192188 0,03097125 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,02192188 0,03095307 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,0228644 0,03226495 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,0228644 0,03224604 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,0228644 0,03222715 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,0228644 0,03220828 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,0228644 0,03218943 ! vesicle docking GO:0048278 47 24 0,000 0,0228644 0,03217061 ! spinal cord development GO:0021510 47 24 0,000 0,0228644 0,03215181 ! vacuole organization GO:0007033 43 24 0,000 0,0228644 0,03213303 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,0228644 0,03211427 ! digestive system process GO:0022600 39 24 0,000 0,0228644 0,03209553 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,0228644 0,03207682 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,0228644 0,03205812 ! regulation of behavior GO:0050795 43 24 0,000 0,0228644 0,03203945 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,0228644 0,0320208 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,0228644 0,03200218 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,0228644 0,03198357 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,0228644 0,03196499 ! membrane depolarization GO:0051899 39 24 0,000 0,0228644 0,03194642 ! pallium development GO:0021543 49 24 0,000 0,0228644 0,03192788 ! pentose metabolic process GO:0019321 35 24 0,000 0,0228644 0,03190936 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,0228644 0,03189086 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,0228644 0,03187239 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,0228644 0,03185393 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,0228644 0,0318355 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,0228644 0,03181709 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,0228644 0,03179869 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,0228644 0,03178032 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,0228644 0,03176198 ! regulation of amine transport GO:0051952 40 24 0,000 0,0228644 0,03174365 ! protein tetramerization GO:0051262 52 24 0,000 0,0228644 0,03172534 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,02380604 0,03301288 ! myelination GO:0042552 45 25 0,000 0,02380604 0,03299386 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,02380604 0,03297487 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,02380604 0,03295589 ! phototransduction GO:0007602 33 25 0,000 0,02380604 0,03293694 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,02380604 0,03291801 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,02380604 0,0328991 ! sperm motility GO:0030317 31 25 0,000 0,02380604 0,03288022 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,02380604 0,03286135 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,02380604 0,03284251 ! receptor metabolic process GO:0043112 46 25 0,000 0,02380604 0,03282369 ! chromosome condensation GO:0030261 45 25 0,000 0,02380604 0,03280489 ! response to starvation GO:0042594 42 25 0,000 0,02380604 0,03278611 ! osteoblast differentiation GO:0001649 60 25 0,000 0,02380604 0,03276736 ! neural crest cell development GO:0014032 54 25 0,000 0,02380604 0,03274862 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,02380604 0,03272991 ! negative regulation of cell development GO:0010721 73 25 0,000 0,02380604 0,03271122 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,02380604 0,03269255 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,02380604 0,0326739 ! interaction with host GO:0051701 62 25 0,000 0,02380604 0,03265527 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,02380604 0,03263666 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,02380604 0,03261808 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,02380604 0,03259951 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,02380604 0,03258097 ! immunoglobulin production GO:0002377 55 25 0,000 0,02380604 0,03256244 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,02380604 0,03254394 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,02380604 0,03252546 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,02380604 0,032507 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,02380604 0,03248857 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,02380604 0,03247015 ! telomere organization GO:0032200 43 25 0,000 0,02380604 0,03245175 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,02380604 0,03243338 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,02380604 0,03241502 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,02474681 0,03367694 ! embryonic pattern specification GO:0009880 44 26 0,000 0,02474681 0,0336579 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,02474681 0,03363889 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,02474681 0,03361989 ! initiation of viral infection GO:0019059 57 26 0,000 0,02474681 0,03360092 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,02474681 0,03358197 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,02474681 0,03356304 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,02474681 0,03354413 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,02474681 0,03352524 ! molting cycle process GO:0022404 50 26 0,000 0,02474681 0,03350638 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,02474681 0,03348753 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,02474681 0,03346871 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,02474681 0,03344991 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,02474681 0,03343112 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,02474681 0,03341236 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,02474681 0,03339362 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,02474681 0,03337491 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,02474681 0,03335621 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,02474681 0,03333753 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,02474681 0,03331888 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,02474681 0,03330024 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,02474681 0,03328163 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,02474681 0,03326303 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,02474681 0,03324446 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,02474681 0,03322591 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,02474681 0,03320738 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,02474681 0,03318887 ! blastocyst development GO:0001824 49 26 0,000 0,02474681 0,03317038 ! leukocyte proliferation GO:0070661 52 26 0,000 0,02474681 0,03315191 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,02474681 0,03313346 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,02474681 0,03311503 ! neuron fate commitment GO:0048663 48 27 0,000 0,02568671 0,03435365 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,02568671 0,03433456 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,02568671 0,0343155 ! iron ion transport GO:0006826 59 27 0,000 0,02568671 0,03429646 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,02568671 0,03427744 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,02568671 0,03425843 ! protein amino acid acylation GO:0043543 55 27 0,000 0,02568671 0,03423945 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,02568671 0,0342205 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,02568671 0,03420156 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,02568671 0,03418264 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,02568671 0,03416375 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,02568671 0,03414487 ! autophagy GO:0006914 41 27 0,000 0,02568671 0,03412602 ! male gonad development GO:0008584 44 27 0,000 0,02568671 0,03410718 ! response to toxin GO:0009636 47 27 0,000 0,02568671 0,03408837 ! primary neural tube formation GO:0014020 51 27 0,000 0,02568671 0,03406958 ! base-excision repair GO:0006284 41 27 0,000 0,02568671 0,03405081 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,02568671 0,03403206 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,02568671 0,03401333 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,02568671 0,03399462 ! glutathione metabolic process GO:0006749 39 27 0,000 0,02568671 0,03397593 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,02568671 0,03395726 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,02568671 0,03393861 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,02568671 0,03391999 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,02568671 0,03390138 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,02662573 0,03512143 ! circadian rhythm GO:0007623 50 28 0,000 0,02662573 0,03510219 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,02662573 0,03508297 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,02662573 0,03506376 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,02662573 0,03504458 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,02662573 0,03502542 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,02662573 0,03500628 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,02662573 0,03498716 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,02662573 0,03496807 ! synaptogenesis GO:0007416 42 28 0,000 0,02662573 0,03494899 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,02662573 0,03492993 ! lipid oxidation GO:0034440 43 28 0,000 0,02662573 0,0349109 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,02662573 0,03489188 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,02662573 0,03487289 ! translational initiation GO:0006413 65 29 0,000 0,02756387 0,03608198 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,02756387 0,03606236 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,02756387 0,03604276 ! regulation of pH GO:0006885 43 29 0,000 0,02756387 0,03602318 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,02756387 0,03600362 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,02756387 0,03598409 ! catechol metabolic process GO:0009712 54 29 0,000 0,02756387 0,03596457 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,02756387 0,03594508 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,02756387 0,03592561 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,02756387 0,03590616 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,02756387 0,03588673 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,02756387 0,03586732 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,02756387 0,03584793 ! cell fate determination GO:0001709 60 29 0,000 0,02756387 0,03582856 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,02756387 0,03580922 ! detection of light stimulus GO:0009583 38 29 0,000 0,02756387 0,03578989 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,02756387 0,03577059 ! tissue homeostasis GO:0001894 48 29 0,000 0,02756387 0,03575131 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,02756387 0,03573204 ! phenol metabolic process GO:0018958 55 30 0,000 0,02850114 0,03692717 ! zinc ion transport GO:0006829 45 30 0,000 0,02850114 0,03690729 ! membrane docking GO:0022406 61 30 0,000 0,02850114 0,03688744 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,02850114 0,03686761 ! cell junction assembly GO:0034329 78 30 0,000 0,02850114 0,0368478 ! regulation of innate immune response GO:0045088 51 30 0,000 0,02850114 0,03682801 ! acute-phase response GO:0006953 49 30 0,000 0,02850114 0,03680824 ! myofibril assembly GO:0030239 47 30 0,000 0,02850114 0,03678849 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,02850114 0,03676877 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,02850114 0,03674906 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,02850114 0,03672938 ! phospholipid transport GO:0015914 51 30 0,000 0,02850114 0,03670972 ! ensheathment of neurons GO:0007272 57 30 0,000 0,02850114 0,03669008 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,02850114 0,03667045 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,02850114 0,03665086 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,02850114 0,03663128 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,02850114 0,03661172 ! eye morphogenesis GO:0048592 60 30 0,000 0,02850114 0,03659218 ! response to heat GO:0009408 50 30 0,000 0,02850114 0,03657267 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,02943754 0,03775412 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,02943754 0,03773401 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,02943754 0,03771391 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,02943754 0,03769384 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,02943754 0,03767379 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,02943754 0,03765376 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,02943754 0,03763376 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,02943754 0,03761377 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,02943754 0,0375938 ! ovulation cycle process GO:0022602 49 31 0,000 0,02943754 0,03757386 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,02943754 0,03755394 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,02943754 0,03753404 ! peptide transport GO:0015833 55 31 0,000 0,02943754 0,03751416 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,02943754 0,0374943 ! iron ion homeostasis GO:0055072 54 31 0,000 0,02943754 0,03747446 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,02943754 0,03745464 ! mesoderm formation GO:0001707 69 31 0,000 0,02943754 0,03743485 ! natural killer cell activation GO:0030101 45 31 0,000 0,02943754 0,03741507 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,02943754 0,03739532 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,02943754 0,03737558 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,02943754 0,03735587 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,02943754 0,03733618 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,02943754 0,03731651 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,03037307 0,03848215 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,03037307 0,0384619 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,03037307 0,03844167 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,03037307 0,03842146 ! cholesterol transport GO:0030301 56 32 0,000 0,03037307 0,03840127 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,03037307 0,0383811 ! spliceosome assembly GO:0000245 67 32 0,000 0,03037307 0,03836095 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,03037307 0,03834082 ! metanephros development GO:0001656 74 32 0,000 0,03037307 0,03832072 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,03037307 0,03830063 ! response to ionizing radiation GO:0010212 65 32 0,000 0,03037307 0,03828057 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,03037307 0,03826053 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,03037307 0,03824051 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,03037307 0,03822051 ! muscle cell development GO:0055001 49 32 0,000 0,03037307 0,03820053 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,03037307 0,03818057 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,03037307 0,03816063 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,03037307 0,03814072 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,03037307 0,03812082 ! ovulation cycle GO:0042698 51 32 0,000 0,03037307 0,03810094 ! peripheral nervous system development GO:0007422 64 32 0,000 0,03037307 0,03808109 ! BMP signaling pathway GO:0030509 64 32 0,000 0,03037307 0,03806126 ! hindbrain development GO:0030902 61 32 0,000 0,03037307 0,03804144 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,03037307 0,03802165 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,03037307 0,03800188 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,03037307 0,03798213 ! gene silencing GO:0016458 65 32 0,000 0,03037307 0,03796239 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,03130773 0,03911028 ! post-embryonic development GO:0009791 69 33 0,000 0,03130773 0,03908998 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,03130773 0,03906971 ! protein targeting to membrane GO:0006612 68 33 0,000 0,03130773 0,03904945 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,03130773 0,03902922 ! ceramide metabolic process GO:0006672 64 33 0,000 0,03130773 0,03900901 ! formation of primary germ layer GO:0001704 72 33 0,000 0,03130773 0,03898882 ! cell fate specification GO:0001708 52 33 0,000 0,03130773 0,03896865 ! sterol transport GO:0015918 57 33 0,000 0,03130773 0,0389485 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,03130773 0,03892837 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,03130773 0,03890826 ! adult locomotory behavior GO:0008344 59 33 0,000 0,03130773 0,03888818 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,03130773 0,03886811 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,03130773 0,03884806 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,03224152 0,03998613 ! glial cell differentiation GO:0010001 63 34 0,000 0,03224152 0,03996553 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,03224152 0,03994495 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,03224152 0,03992439 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,03224152 0,03990385 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,03224152 0,03988334 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,03224152 0,03986284 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,03224152 0,03984237 ! mismatch repair GO:0006298 46 34 0,000 0,03224152 0,03982192 ! spermatid development GO:0007286 63 34 0,000 0,03224152 0,03980148 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,03224152 0,03978107 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,03224152 0,03976068 ! placenta development GO:0001890 53 34 0,000 0,03224152 0,03974031 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,03224152 0,03971996 ! regulation of muscle development GO:0048634 70 35 0,000 0,03317444 0,04084836 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,03317444 0,04082746 ! negative regulation of secretion GO:0051048 63 35 0,000 0,03317444 0,04080659 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,03317444 0,04078574 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,03317444 0,04076491 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,03317444 0,0407441 ! odontogenesis GO:0042476 66 35 0,000 0,03317444 0,04072331 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,03317444 0,04070255 ! female gonad development GO:0008585 58 35 0,000 0,03317444 0,0406818 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,03317444 0,04066108 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,03317444 0,04064037 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,03317444 0,04061969 ! cytokine production GO:0001816 59 35 0,000 0,03317444 0,04059903 ! neural tube formation GO:0001841 67 35 0,000 0,03317444 0,04057839 ! vesicle localization GO:0051648 64 35 0,000 0,03317444 0,04055777 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,03410649 0,04167608 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,03410649 0,04165493 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,03410649 0,04163379 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,03410649 0,04161268 ! cell junction organization GO:0034330 86 36 0,000 0,03410649 0,04159159 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,03410649 0,04157052 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,03410649 0,04154947 ! positive regulation of cell development GO:0010720 80 36 0,000 0,03410649 0,04152844 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,03410649 0,04150744 ! regulation of proteolysis GO:0030162 72 36 0,000 0,03410649 0,04148645 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,03410649 0,04146549 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,03410649 0,04144455 ! aerobic respiration GO:0009060 55 36 0,000 0,03410649 0,04142363 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,03410649 0,04140273 ! embryonic organ development GO:0048568 57 36 0,000 0,03410649 0,04138185 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,03410649 0,04136099 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,03410649 0,04134015 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,03503767 0,04244745 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,03503767 0,04242609 ! sister chromatid segregation GO:0000819 58 37 0,000 0,03503767 0,04240474 ! actomyosin structure organization GO:0031032 62 37 0,000 0,03503767 0,04238343 ! organic anion transport GO:0015711 68 37 0,000 0,03503767 0,04236213 ! tissue remodeling GO:0048771 76 37 0,000 0,03503767 0,04234085 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,03503767 0,04231959 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,03503767 0,04229836 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,03503767 0,04227715 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,03503767 0,04225596 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,03503767 0,04223479 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,03503767 0,04221364 ! glycogen metabolic process GO:0005977 61 37 0,000 0,03503767 0,04219251 ! pigment metabolic process GO:0042440 80 37 0,000 0,03503767 0,0421714 ! spermatid differentiation GO:0048515 66 37 0,000 0,03503767 0,04215032 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,03503767 0,04212925 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,03596799 0,04322626 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,03596799 0,04320468 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,03596799 0,04318312 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,03596799 0,04316158 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,03596799 0,04314007 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,03596799 0,04311857 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,03596799 0,0430971 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,03596799 0,04307565 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,03596799 0,04305422 ! lipid homeostasis GO:0055088 67 38 0,000 0,03596799 0,04303281 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,03596799 0,04301142 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,03596799 0,04299005 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,03596799 0,04296871 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,03596799 0,04294738 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,03596799 0,04292608 ! glucan metabolic process GO:0044042 62 38 0,000 0,03596799 0,0429048 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,03689744 0,04399169 ! mammary gland development GO:0030879 86 39 0,000 0,03689744 0,0439699 ! learning GO:0007612 77 39 0,000 0,03689744 0,04394813 ! ear morphogenesis GO:0042471 60 39 0,000 0,03689744 0,04392639 ! organic ether metabolic process GO:0018904 55 39 0,000 0,03689744 0,04390466 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,03689744 0,04388296 ! segmentation GO:0035282 67 39 0,000 0,03689744 0,04386128 ! ion transmembrane transport GO:0034220 66 39 0,000 0,03689744 0,04383962 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,03689744 0,04381798 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,03689744 0,04379636 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,03689744 0,04377477 ! RNA modification GO:0009451 57 39 0,000 0,03689744 0,04375319 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,03689744 0,04373164 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,03782602 0,04481015 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,03782602 0,04478809 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,03782602 0,04476606 ! feeding behavior GO:0007631 59 40 0,000 0,03782602 0,04474405 ! negative regulation of binding GO:0051100 72 40 0,000 0,03782602 0,04472207 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,03782602 0,0447001 ! mesenchymal cell development GO:0014031 87 40 0,000 0,03782602 0,04467816 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,03782602 0,04465623 ! maintenance of protein location GO:0045185 91 40 0,000 0,03782602 0,04463433 ! cytokinesis GO:0000910 72 40 0,000 0,03782602 0,04461245 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,03875374 0,04568422 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,03875374 0,04566185 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,03875374 0,0456395 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,03875374 0,04561717 ! gliogenesis GO:0042063 88 41 0,000 0,03875374 0,04559487 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,03875374 0,04557258 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,03875374 0,04555032 ! T cell differentiation GO:0030217 81 41 0,000 0,03875374 0,04552808 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,03875374 0,04550586 ! female gamete generation GO:0007292 61 41 0,000 0,03875374 0,04548366 ! polyol metabolic process GO:0019751 66 41 0,000 0,03875374 0,04546148 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,03875374 0,04543933 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,0396806 0,04650342 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,0396806 0,04648078 ! regulation of tube size GO:0035150 71 42 0,000 0,0396806 0,04645816 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,0396806 0,04643556 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,0396806 0,04641299 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,0396806 0,04639044 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,0396806 0,04636791 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,0396806 0,0463454 ! neuron migration GO:0001764 79 42 0,000 0,0396806 0,04632291 ! regulation of protein secretion GO:0050708 71 42 0,000 0,0396806 0,04630044 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,0396806 0,046278 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,04060659 0,04733501 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,04060659 0,04731209 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,04060659 0,04728919 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,04060659 0,04726631 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,04060659 0,04724345 ! glucose transport GO:0015758 65 43 0,000 0,04060659 0,04722062 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,04060659 0,04719781 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,04060659 0,04717502 ! neural tube development GO:0021915 77 43 0,000 0,04060659 0,04715225 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,04060659 0,0471295 ! striated muscle contraction GO:0006941 77 43 0,000 0,04060659 0,04710678 ! phagocytosis GO:0006909 90 43 0,000 0,04060659 0,04708408 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,04060659 0,0470614 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,04153172 0,04811041 ! hexose transport GO:0008645 67 44 0,000 0,04153172 0,04808726 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,04153172 0,04806413 ! male sex differentiation GO:0046661 76 44 0,000 0,04153172 0,04804102 ! double-strand break repair GO:0006302 81 44 0,000 0,04153172 0,04801794 ! biopolymer methylation GO:0043414 84 44 0,000 0,04153172 0,04799487 ! B cell differentiation GO:0030183 107 44 0,000 0,04153172 0,04797183 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,04153172 0,04794881 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,04153172 0,04792582 ! developmental growth GO:0048589 82 44 0,000 0,04153172 0,04790284 ! maintenance of location in cell GO:0051651 97 44 0,000 0,04153172 0,04787989 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,04245599 0,04892199 ! glycolysis GO:0006096 65 45 0,000 0,04245599 0,04889857 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,04245599 0,04887518 ! leukocyte migration GO:0050900 68 45 0,000 0,04245599 0,0488518 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,04245599 0,04882845 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,04245599 0,04880512 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,04245599 0,04878181 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,04245599 0,04875853 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,04245599 0,04873527 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,04245599 0,04871203 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,04245599 0,04868881 ! cell growth GO:0016049 84 45 0,000 0,04245599 0,04866561 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,0433794 0,0497004 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,0433794 0,04967675 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,0433794 0,04965311 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,0433794 0,0496295 ! pigmentation GO:0043473 100 46 0,000 0,0433794 0,04960591 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,0433794 0,04958235 ! positive regulation of defense response GO:0031349 76 47 0,000 0,04430195 0,05061277 ! endosome transport GO:0016197 108 47 0,000 0,04430195 0,05058875 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,04430195 0,05056475 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,04430195 0,05054078 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,04430195 0,05051682 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,04430195 0,05049289 ! JNK cascade GO:0007254 91 47 0,000 0,04430195 0,05046899 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,04430195 0,0504451 ! methylation GO:0032259 90 47 0,000 0,04430195 0,05042124 ! protein homooligomerization GO:0051260 76 47 0,000 0,04430195 0,0503974 ! mitochondrial transport GO:0006839 82 48 0,000 0,04522364 0,05142159 ! Notch signaling pathway GO:0007219 96 48 0,000 0,04522364 0,0513973 ! cellular component disassembly GO:0022411 86 48 0,000 0,04522364 0,05137303 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,04522364 0,05134879 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,04522364 0,05132457 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,04522364 0,05130037 ! activation of caspase activity GO:0006919 84 48 0,000 0,04522364 0,0512762 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,04522364 0,05125204 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,04522364 0,05122791 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,04522364 0,05120381 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,04614448 0,05222183 ! regulation of action potential GO:0001508 95 49 0,000 0,04614448 0,05219728 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,04614448 0,05217275 ! regulation of ion transport GO:0043269 77 49 0,000 0,04614448 0,05214824 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,04614448 0,05212376 ! peptide metabolic process GO:0006518 76 49 0,000 0,04614448 0,0520993 ! response to temperature stimulus GO:0009266 76 49 0,000 0,04614448 0,05207486 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,04614448 0,05205045 ! endocrine system development GO:0035270 104 49 0,000 0,04614448 0,05202606 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,04614448 0,05200169 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,04614448 0,05197735 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,04614448 0,05195302 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,04614448 0,05192872 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,04706445 0,05293926 ! neuromuscular process GO:0050905 99 50 0,000 0,04706445 0,05291452 ! regulation of ossification GO:0030278 117 50 0,000 0,04706445 0,0528898 ! inner ear development GO:0048839 79 50 0,000 0,04706445 0,05286511 ! histone modification GO:0016570 91 50 0,000 0,04706445 0,05284044 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,04706445 0,0528158 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,04706445 0,05279117 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,04706445 0,05276657 ! positive regulation of binding GO:0051099 78 51 0,000 0,04798357 0,05377199 ! viral infectious cycle GO:0019058 99 51 0,000 0,04798357 0,05374696 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,04798357 0,05372195 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,04798357 0,05369696 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,04798357 0,053672 ! excretion GO:0007588 83 51 0,000 0,04798357 0,05364706 ! chromatin remodeling GO:0006338 109 51 0,000 0,04798357 0,05362214 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,04798357 0,05359725 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,04798357 0,05357238 ! vesicle organization GO:0016050 107 51 0,000 0,04798357 0,05354753 ! regulation of cell shape GO:0008360 125 51 0,000 0,04798357 0,0535227 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,04798357 0,0534979 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,04890183 0,05449644 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,04890183 0,05447121 ! membrane fusion GO:0006944 110 52 0,000 0,04890183 0,054446 ! covalent chromatin modification GO:0016569 101 52 0,000 0,04890183 0,05442082 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,04890183 0,05439566 ! amino acid activation GO:0043038 92 52 0,000 0,04890183 0,05437052 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,04890183 0,05434541 ! synapse organization GO:0050808 85 52 0,000 0,04890183 0,05432032 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,04981924 0,05531384 ! RNA catabolic process GO:0006401 93 53 0,000 0,04981924 0,05528833 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,04981924 0,05526284 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,04981924 0,05523737 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,04981924 0,05521192 ! cell maturation GO:0048469 100 53 0,000 0,04981924 0,05518651 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,04981924 0,05516111 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,04981924 0,05513574 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,05073579 0,05612428 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,05073579 0,05609849 ! cell recognition GO:0008037 85 54 0,000 0,05073579 0,05607272 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,05073579 0,05604698 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,05073579 0,05602126 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,05073579 0,05599556 ! chloride transport GO:0006821 90 55 0,000 0,05165149 0,05698005 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,05165149 0,05695394 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,05165149 0,05692785 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,05165149 0,05690178 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,05165149 0,05687574 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,05165149 0,05684972 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,05165149 0,05682373 ! aging GO:0007568 103 55 0,000 0,05165149 0,05679775 ! gastrulation GO:0007369 112 55 0,000 0,05165149 0,05677181 ! heart morphogenesis GO:0003007 97 55 0,000 0,05165149 0,05674588 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,05165149 0,05671998 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,05165149 0,05669411 ! regulation of actin filament length GO:0030832 105 56 0,000 0,05256634 0,05767196 ! sensory perception of smell GO:0007608 80 56 0,000 0,05256634 0,05764567 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,05256634 0,05761941 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,05256634 0,05759317 ! regulation of DNA replication GO:0006275 101 56 0,000 0,05256634 0,05756696 ! proton transport GO:0015992 94 56 0,000 0,05256634 0,05754077 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,05256634 0,0575146 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,05348033 0,05848803 ! muscle fiber development GO:0048747 112 57 0,000 0,05348033 0,05846146 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,05348033 0,05843491 ! lipid modification GO:0030258 97 57 0,000 0,05348033 0,05840839 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,05348033 0,05838189 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,05348033 0,05835541 ! maintenance of location GO:0051235 118 57 0,000 0,05348033 0,05832896 ! hydrogen transport GO:0006818 97 58 0,000 0,05439347 0,05929801 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,05439347 0,05927115 ! regulation of endocytosis GO:0030100 91 58 0,000 0,05439347 0,05924432 ! adult behavior GO:0030534 99 58 0,000 0,05439347 0,05921751 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,05439347 0,05919073 ! positive regulation of secretion GO:0051047 95 59 0,000 0,05530577 0,06015627 ! regulation of cellular component size GO:0032535 109 59 0,000 0,05530577 0,06012909 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,05530577 0,06010193 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,05530577 0,0600748 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,05530577 0,06004769 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,05530577 0,0600206 ! establishment of organelle localization GO:0051656 109 59 0,000 0,05530577 0,05999354 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,05621721 0,06095476 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,05621721 0,0609273 ! regulation of heart contraction GO:0008016 110 60 0,000 0,05621721 0,06089987 ! camera-type eye development GO:0043010 116 60 0,000 0,05621721 0,06087246 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,05621721 0,06084508 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,05621721 0,06081772 ! kidney development GO:0001822 122 60 0,000 0,05621721 0,06079038 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,0571278 0,0617473 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,0571278 0,06171957 ! mesoderm development GO:0007498 119 61 0,000 0,0571278 0,06169187 ! tRNA processing GO:0008033 89 61 0,000 0,0571278 0,0616642 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,0571278 0,06163654 ! ear development GO:0043583 103 62 0,000 0,05803755 0,06259002 ! viral reproductive process GO:0022415 126 62 0,000 0,05803755 0,06256198 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,05803755 0,06253396 ! gonad development GO:0008406 98 62 0,000 0,05803755 0,06250597 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,05803755 0,062478 ! regulation of mitosis GO:0007088 105 63 0,000 0,05894644 0,06342806 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,05894644 0,06339971 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,05894644 0,06337138 ! detection of external stimulus GO:0009581 91 63 0,000 0,05894644 0,06334307 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,05894644 0,0633148 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,05894644 0,06328654 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,05985449 0,06423279 ! cell redox homeostasis GO:0045454 102 64 0,000 0,05985449 0,06420415 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,05985449 0,06417554 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,05985449 0,06414695 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,05985449 0,06411839 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,05985449 0,06408986 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,0607617 0,06503232 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,0607617 0,0650034 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,0607617 0,06497451 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,0607617 0,06494565 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,0607617 0,06491681 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,06166806 0,0658559 ! actin filament organization GO:0007015 148 66 0,000 0,06166806 0,06582669 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,06166806 0,06579749 ! extracellular matrix organization GO:0030198 133 66 0,000 0,06166806 0,06576833 ! secondary metabolic process GO:0019748 116 66 0,000 0,06166806 0,06573919 ! developmental maturation GO:0021700 116 66 0,000 0,06166806 0,06571007 ! cell projection assembly GO:0030031 120 66 0,000 0,06166806 0,06568099 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,06257357 0,06661594 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,06257357 0,06658647 ! activation of MAPK activity GO:0000187 115 67 0,000 0,06257357 0,06655704 ! lung development GO:0030324 144 67 0,000 0,06257357 0,06652763 ! chromosome segregation GO:0007059 113 67 0,000 0,06257357 0,06649824 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,06257357 0,06646888 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,06257357 0,06643955 ! hexose catabolic process GO:0019320 104 67 0,000 0,06257357 0,06641024 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,06257357 0,06638096 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,06257357 0,0663517 ! adaptive immune response GO:0002250 119 67 0,000 0,06257357 0,06632247 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,06257357 0,06629327 ! amino acid transport GO:0006865 125 68 0,000 0,06347824 0,06722212 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,06347824 0,06719255 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,06347824 0,067163 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,06347824 0,06713348 ! viral reproduction GO:0016032 134 68 0,000 0,06347824 0,06710398 ! regulation of lipase activity GO:0060191 130 68 0,000 0,06347824 0,06707451 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,06347824 0,06704506 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,06438207 0,06796984 ! urogenital system development GO:0001655 137 69 0,000 0,06438207 0,06794003 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,06438207 0,06791024 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,06438207 0,06788048 ! antigen processing and presentation GO:0019882 104 69 0,000 0,06438207 0,06785075 ! appendage morphogenesis GO:0035107 135 70 0,000 0,06528506 0,06877226 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,06528506 0,06874217 ! amine catabolic process GO:0009310 117 71 0,000 0,0661872 0,0696616 ! reproductive structure development GO:0048608 113 71 0,000 0,0661872 0,06963114 ! appendage development GO:0048736 136 71 0,000 0,0661872 0,0696007 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,0661872 0,0695703 ! B cell activation GO:0042113 160 71 0,000 0,0661872 0,06953992 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,0661872 0,06950956 ! regulation of immune effector process GO:0002697 137 71 0,000 0,0661872 0,06947924 ! acute inflammatory response GO:0002526 113 72 0,000 0,06708851 0,07039466 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,06708851 0,07036397 ! carbohydrate transport GO:0008643 110 72 0,000 0,06708851 0,07033331 ! respiratory system development GO:0060541 153 72 0,000 0,06708851 0,07030268 ! learning or memory GO:0007611 147 73 0,000 0,06798897 0,07121526 ! regulation of blood pressure GO:0008217 125 73 0,000 0,06798897 0,07118427 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,06798897 0,07115331 ! axon guidance GO:0007411 139 73 0,000 0,06798897 0,07112237 ! fertilization GO:0009566 90 73 0,000 0,06798897 0,07109147 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,06888859 0,07200085 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,06888859 0,07196959 ! neurotransmitter transport GO:0006836 123 74 0,000 0,06888859 0,07193835 ! exocytosis GO:0006887 133 74 0,000 0,06888859 0,07190714 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,06888859 0,07187596 ! eye development GO:0001654 143 74 0,000 0,06888859 0,0718448 ! organelle localization GO:0051640 136 74 0,000 0,06888859 0,07181367 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,06978738 0,07271912 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,06978738 0,07268764 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,06978738 0,07265618 ! rhythmic process GO:0048511 128 75 0,000 0,06978738 0,07262476 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,06978738 0,07259336 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,07068533 0,07349564 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,07068533 0,07346389 ! defense response to bacterium GO:0042742 89 76 0,000 0,07068533 0,07343217 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,07068533 0,07340048 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,07068533 0,07336881 ! regulation of catabolic process GO:0009894 161 76 0,000 0,07068533 0,07333717 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,07158244 0,07423593 ! blood coagulation GO:0007596 146 78 0,000 0,07247872 0,07513304 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,07247872 0,07510069 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,07337416 0,07599579 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,07337416 0,07596309 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,07337416 0,07593042 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,07337416 0,07589777 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,07426876 0,07679013 ! muscle cell differentiation GO:0042692 159 80 0,000 0,07426876 0,07675715 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,07426876 0,07672419 ! protein import into nucleus GO:0006606 158 80 0,000 0,07426876 0,07669126 ! inorganic anion transport GO:0015698 138 80 0,000 0,07426876 0,07665836 ! T cell activation GO:0042110 168 81 0,000 0,07516253 0,07754762 ! response to hypoxia GO:0001666 171 81 0,000 0,07516253 0,07751438 ! digestion GO:0007586 112 81 0,000 0,07516253 0,07748117 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,07516253 0,07744799 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,07516253 0,07741483 ! nuclear import GO:0051170 161 81 0,000 0,07516253 0,07738171 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,07516253 0,07734861 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,07605547 0,07823406 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,07605547 0,07820062 ! response to drug GO:0042493 143 82 0,000 0,07605547 0,07816722 ! response to nutrient GO:0007584 125 82 0,000 0,07605547 0,07813384 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,07605547 0,0781005 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,07605547 0,07806718 ! response to oxygen levels GO:0070482 176 83 0,000 0,07694758 0,0789492 ! regulation of lyase activity GO:0051339 160 83 0,000 0,07694758 0,07891554 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,07783885 0,0797956 ! hemostasis GO:0007599 158 84 0,000 0,07783885 0,07976162 ! negative regulation of transport GO:0051051 153 84 0,000 0,07783885 0,07972766 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,07783885 0,07969373 ! nucleosome assembly GO:0006334 122 85 0,000 0,07872929 0,08057111 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,07872929 0,08053685 ! amine biosynthetic process GO:0009309 138 86 0,000 0,07961891 0,08141228 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,07961891 0,08137769 ! chromatin assembly GO:0031497 124 86 0,000 0,07961891 0,08134314 ! tube morphogenesis GO:0035239 176 86 0,000 0,07961891 0,08130861 ! alcohol catabolic process GO:0046164 130 86 0,000 0,07961891 0,08127411 ! amine transport GO:0015837 155 86 0,000 0,07961891 0,08123965 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,08050769 0,0821117 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,08050769 0,08207691 ! protein localization in nucleus GO:0034504 176 87 0,000 0,08050769 0,08204214 ! regulation of protein transport GO:0051223 154 87 0,000 0,08050769 0,08200741 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,08139564 0,08287682 ! regulation of DNA binding GO:0051101 155 88 0,000 0,08139564 0,08284176 ! gland development GO:0048732 206 88 0,000 0,08139564 0,08280673 ! regulation of neurological system process GO:0031644 148 88 0,000 0,08139564 0,08277173 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,08139564 0,08273676 ! cellular defense response GO:0006968 114 89 0,000 0,08228277 0,08360319 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,08228277 0,0835679 ! ossification GO:0001503 188 90 0,000 0,08316907 0,0844324 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,08316907 0,08439679 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,08316907 0,08436121 ! sex differentiation GO:0007548 145 90 0,000 0,08316907 0,08432566 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,08316907 0,08429014 ! bone development GO:0060348 189 91 0,000 0,08405454 0,08515168 ! sterol metabolic process GO:0016125 152 91 0,000 0,08405454 0,08511584 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,08405454 0,08508003 ! regulation of defense response GO:0031347 149 92 0,000 0,08493919 0,08593931 ! nucleosome organization GO:0034728 138 92 0,000 0,08493919 0,08590319 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,08493919 0,0858671 ! vitamin metabolic process GO:0006766 139 92 0,000 0,08493919 0,08583103 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,08582301 0,08668773 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,08582301 0,08665135 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,08582301 0,086615 ! regulation of membrane potential GO:0042391 164 93 0,000 0,08582301 0,08657869 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,08582301 0,0865424 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,08670601 0,08739617 ! female pregnancy GO:0007565 164 94 0,000 0,08670601 0,08735957 ! regulation of T cell activation GO:0050863 158 94 0,000 0,08670601 0,08732301 ! forebrain development GO:0030900 188 95 0,000 0,08758818 0,08817455 ! leukocyte differentiation GO:0002521 202 96 0,000 0,08846954 0,08902455 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,08846954 0,08898733 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,08846954 0,08895015 ! positive regulation of immune response GO:0050778 156 96 0,000 0,08846954 0,08891299 ! detection of stimulus GO:0051606 151 96 0,000 0,08846954 0,08887587 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,08935007 0,08972298 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,08935007 0,08968555 ! protein ubiquitination GO:0016567 217 97 0,000 0,08935007 0,08964815 ! hormone metabolic process GO:0042445 157 97 0,000 0,08935007 0,08961078 ! regulation of protein localization GO:0032880 176 97 0,000 0,08935007 0,08957344 ! response to virus GO:0009615 160 98 0,000 0,09022977 0,09041767 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,09022977 0,09038003 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,09022977 0,09034242 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,09110866 0,09118446 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,09110866 0,09114655 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,09110866 0,09110866 GO:0060538|skeletal muscle organ development,