pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/1537-1-real-Parker_GPL1390-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL1390.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! activation of caspase activity by cytochrome c GO:0008635 7 7 2,000 2,981E-08 1,064E-04 ! caspase regulator activity GO:0043028 28 28 2,000 2,754E-06 4,918E-03 ! activation of caspase activity GO:0006919 49 46 2,000 1,262E-05 0,01502496 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 6 6 1,000 1,448E-05 0,01292428 ! positive regulation of caspase activity GO:0043280 55 52 2,000 1,831E-05 0,0130765 GO:0010952|positive regulation of peptidase activity, ! proteasome regulatory particle GO:0005838 8 7 1,000 2,026E-05 0,01205556 ! sodium:phosphate symporter activity GO:0005436 7 7 1,000 2,026E-05 0,01033334 ! phosphate transport GO:0006817 9 8 1,000 2,699E-05 0,01204847 ! G1 DNA damage checkpoint GO:0031571 8 8 1,000 2,699E-05 0,01070975 ! caspase inhibitor activity GO:0043027 8 8 1,000 2,699E-05 9,639E-03 ! mitochondrial respiratory chain GO:0005746 65 63 2,000 3,268E-05 0,01060879 ! respiratory chain GO:0070469 66 64 2,000 3,427E-05 0,01019675 ! regulation of caspase activity GO:0043281 70 67 2,000 3,933E-05 0,01080246 ! regulation of endopeptidase activity GO:0052548 72 69 2,000 4,296E-05 0,0109574 ! proteasome accessory complex GO:0022624 11 10 1,000 4,333E-05 0,01031512 ! regulation of peptidase activity GO:0052547 78 74 2,000 5,299E-05 0,0118261 ! phosphate transmembrane transporter activity GO:0015114 13 12 1,000 6,347E-05 0,01333328 ! G1/S transition checkpoint GO:0031575 13 13 1,000 7,497E-05 0,01487334 ! electron transport chain GO:0022900 102 100 2,000 1,301E-04 0,02444971 ! DNA fragmentation involved in apoptosis GO:0006309 17 17 1,000 1,304E-04 0,02328484 ! protein phosphatase type 2A complex GO:0000159 20 18 1,000 1,466E-04 0,02493338 ! caspase activator activity GO:0008656 19 19 1,000 1,638E-04 0,0265844 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 24 21 1,000 2,009E-04 0,03119134 ! cell structure disassembly during apoptosis GO:0006921 21 21 1,000 2,009E-04 0,0298917 ! apoptotic protease activator activity GO:0016505 21 21 1,000 2,009E-04 0,02869603 ! neural tube closure GO:0001843 24 22 1,000 2,209E-04 0,03033372 GO:0060606|tube closure, ! metallocarboxypeptidase activity GO:0004181 23 22 1,000 2,209E-04 0,02921025 ! apoptotic nuclear changes GO:0030262 23 23 1,000 2,417E-04 0,03083146 ! tube lumen formation GO:0035148 26 23 1,000 2,417E-04 0,02976831 ! primary neural tube formation GO:0014020 26 24 1,000 2,636E-04 0,03137358 ! DNA catabolic process, endonucleolytic GO:0000737 24 24 1,000 2,636E-04 0,03036153 ! peptidase activator activity GO:0016504 25 25 1,000 2,863E-04 0,03195156 ! response to heat GO:0009408 26 26 1,000 3,1E-04 0,03354554 ! mitochondrial intermembrane space GO:0005758 28 27 1,000 3,346E-04 0,03514294 ! neural tube formation GO:0001841 29 27 1,000 3,346E-04 0,03413886 ! anion:cation symporter activity GO:0015296 28 27 1,000 3,346E-04 0,03319056 ! DNA damage checkpoint GO:0000077 31 28 1,000 3,601E-04 0,03475718 ! embryonic epithelial tube formation GO:0001838 32 30 1,000 4,139E-04 0,03889998 ! cysteine-type endopeptidase inhibitor activity GO:0004869 32 30 1,000 4,139E-04 0,03790254 ! DNA integrity checkpoint GO:0031570 34 31 1,000 4,422E-04 0,03948037 ! organelle envelope lumen GO:0031970 34 33 1,000 5,016E-04 0,04368452 ! neural tube development GO:0021915 36 34 1,000 5,326E-04 0,04528305 ! carboxypeptidase activity GO:0004180 35 34 1,000 5,326E-04 0,04422996 ! mitotic cell cycle checkpoint GO:0007093 35 35 1,000 5,645E-04 0,04581746 ! metalloexopeptidase activity GO:0008235 36 35 1,000 5,645E-04 0,04479929 ! protein serine/threonine phosphatase complex GO:0008287 38 35 1,000 5,645E-04 0,0438254 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 40 38 1,000 6,658E-04 0,05058923 ! protein serine/threonine phosphatase activity GO:0004722 42 40 1,000 7,379E-04 0,05489633 ! nucleus organization GO:0006997 40 40 1,000 7,379E-04 0,05377599 ! inorganic anion transmembrane transporter activity GO:0015103 42 40 1,000 7,379E-04 0,05270047 ! regulation of translational initiation GO:0006446 41 41 1,000 7,753E-04 0,0542848 ! morphogenesis of embryonic epithelium GO:0016331 44 42 1,000 8,136E-04 0,05587005 ! cellular component disassembly GO:0022411 45 44 1,000 8,928E-04 0,06015668 ! response to temperature stimulus GO:0009266 45 45 1,000 9,338E-04 0,06175252 ! epithelial tube morphogenesis GO:0060562 47 45 1,000 9,338E-04 0,06062975 ! proteasome complex GO:0000502 48 47 1,000 1,018E-03 0,06494419 ! DNA damage response, signal transduction GO:0042770 58 52 1,000 1,246E-03 0,07803598 ! regulation of protein catabolic process GO:0042176 57 54 1,000 1,343E-03 0,08266608 ! DNA catabolic process GO:0006308 55 54 1,000 1,343E-03 0,08126496 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 62 61 1,000 1,71E-03 0,10177213 ! cell cycle checkpoint GO:0000075 64 61 1,000 1,71E-03 0,10010373 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 63 62 1,000 1,766E-03 0,10171234 ! negative regulation of ligase activity GO:0051352 64 63 1,000 1,823E-03 0,10331902 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 66 64 1,000 1,88E-03 0,10492378 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 67 65 1,000 1,939E-03 0,10652663 ! response to unfolded protein GO:0006986 68 66 1,000 1,998E-03 0,10812755 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 69 67 1,000 2,059E-03 0,10972656 ! positive regulation of ligase activity GO:0051351 71 69 1,000 2,182E-03 0,11457941 ! cell-matrix adhesion GO:0007160 76 71 1,000 2,308E-03 0,11946879 ! regulation of ubiquitin-protein ligase activity GO:0051438 74 72 1,000 2,373E-03 0,12105558 ! response to protein stimulus GO:0051789 74 72 1,000 2,373E-03 0,11935057 ! exopeptidase activity GO:0008238 78 73 1,000 2,438E-03 0,12093715 ! regulation of catabolic process GO:0009894 80 75 1,000 2,572E-03 0,12580465 ! tube morphogenesis GO:0035239 79 75 1,000 2,572E-03 0,12410459 ! regulation of ligase activity GO:0051340 78 76 1,000 2,64E-03 0,12568546 ! inorganic anion transport GO:0015698 78 76 1,000 2,64E-03 0,1240317 ! cell-substrate adhesion GO:0031589 81 76 1,000 2,64E-03 0,1224209 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 85 84 1,000 3,214E-03 0,14712735 GO:0010498|proteasomal protein catabolic process, ! cellular respiration GO:0045333 85 85 1,000 3,289E-03 0,148678 ! spindle GO:0005819 89 87 1,000 3,443E-03 0,15367144 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 89 88 1,000 3,521E-03 0,15521272 ! forebrain development GO:0030900 95 91 1,000 3,76E-03 0,16372512 ! protein tyrosine phosphatase activity GO:0004725 104 92 1,000 3,841E-03 0,16524996 ! solute:cation symporter activity GO:0015294 95 94 1,000 4,006E-03 0,17029885 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 97 96 1,000 4,174E-03 0,17536629 ! Ras protein signal transduction GO:0007265 105 99 1,000 4,433E-03 0,18406366 ! tRNA transcription GO:0009304 5 5 0,000 5,081E-03 0,20853827 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 5 5 0,000 5,081E-03 0,20616852 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 5,081E-03 0,20385202 ! benzene and derivative metabolic process GO:0042537 5 5 0,000 5,081E-03 0,20158699 ! response to oxygen radical GO:0000305 5 5 0,000 5,081E-03 0,19937175 ! positive regulation of axon extension GO:0045773 6 5 0,000 5,081E-03 0,19720467 ! negative regulation of bone resorption GO:0045779 5 5 0,000 5,081E-03 0,19508419 ! positive regulation of lipid biosynthetic process GO:0046889 5 5 0,000 5,081E-03 0,19300882 ! regulation of interferon-beta production GO:0032648 6 5 0,000 5,081E-03 0,19097715 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! sodium-independent organic anion transmembrane transporter activity GO:0015347 6 5 0,000 5,081E-03 0,18898781 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 5,081E-03 0,18703948 ! negative regulation of transmembrane transport GO:0034763 5 5 0,000 5,081E-03 0,18513091 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! hypothalamus development GO:0021854 5 5 0,000 5,081E-03 0,1832609 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 5,081E-03 0,18142829 ! N-terminal protein lipidation GO:0006498 5 5 0,000 5,081E-03 0,17963197 ! glycolipid transport GO:0046836 5 5 0,000 5,081E-03 0,17787088 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 5 5 0,000 5,081E-03 0,17614398 ! phosphoinositide 3-kinase binding GO:0043548 5 5 0,000 5,081E-03 0,17445028 ! protein amino acid sulfation GO:0006477 5 5 0,000 5,081E-03 0,17278885 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 6 5 0,000 5,081E-03 0,17115877 ! embryonic camera-type eye development GO:0031076 7 5 0,000 5,081E-03 0,16955915 GO:0048596|embryonic camera-type eye morphogenesis, ! opioid peptide activity GO:0001515 5 5 0,000 5,081E-03 0,16798916 ! selenocysteine incorporation GO:0001514 5 5 0,000 5,081E-03 0,16644798 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 5 5 0,000 5,081E-03 0,16493481 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 5 5 0,000 5,081E-03 0,16344891 ! elastic fiber assembly GO:0048251 5 5 0,000 5,081E-03 0,16198955 ! regulation of mitochondrial membrane permeability GO:0046902 5 5 0,000 5,081E-03 0,16055601 ! neurofilament cytoskeleton organization GO:0060052 5 5 0,000 5,081E-03 0,15914763 ! ruffle membrane GO:0032587 5 5 0,000 5,081E-03 0,15776373 ! regulation of histone modification GO:0031056 5 5 0,000 5,081E-03 0,1564037 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 5,081E-03 0,15506692 ! behavioral response to pain GO:0048266 5 5 0,000 5,081E-03 0,15375279 ! clathrin coat assembly GO:0048268 6 5 0,000 5,081E-03 0,15246075 ! Notch receptor processing GO:0007220 5 5 0,000 5,081E-03 0,15119025 ! cerebral cortex radially oriented cell migration GO:0021799 5 5 0,000 5,081E-03 0,14994074 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 6 5 0,000 5,081E-03 0,14871172 ! serotonin receptor signaling pathway GO:0007210 5 5 0,000 5,081E-03 0,14750268 ! oxidoreductase activity, oxidizing metal ions GO:0016722 5 5 0,000 5,081E-03 0,14631314 ! response to lipid GO:0033993 5 5 0,000 5,081E-03 0,14514264 ! cytoplasmic dynein complex GO:0005868 6 5 0,000 5,081E-03 0,14399071 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 5,081E-03 0,14285692 ! positive regulation of muscle cell differentiation GO:0051149 5 5 0,000 5,081E-03 0,14174085 ! smooth muscle cell differentiation GO:0051145 5 5 0,000 5,081E-03 0,14064209 ! exo-alpha-sialidase activity GO:0004308 5 5 0,000 5,081E-03 0,13956023 GO:0016997|alpha-sialidase activity, ! regulation of odontogenesis GO:0042481 5 5 0,000 5,081E-03 0,13849488 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 5,081E-03 0,13744568 ! formate-tetrahydrofolate ligase activity GO:0004329 5 5 0,000 5,081E-03 0,13641225 ! negative regulation of heart contraction GO:0045822 5 5 0,000 5,081E-03 0,13539425 ! ovulation from ovarian follicle GO:0001542 5 5 0,000 5,081E-03 0,13439133 ! DNA ligation during DNA repair GO:0051103 5 5 0,000 5,081E-03 0,13340316 ! 1-acylglycerophosphocholine O-acyltransferase activity GO:0047184 5 5 0,000 5,081E-03 0,13242941 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 5,081E-03 0,13146978 ! negative regulation of endocytosis GO:0045806 5 5 0,000 5,081E-03 0,13052395 ! microfibril GO:0001527 5 5 0,000 5,081E-03 0,12959164 GO:0043205|fibril, ! parathyroid gland development GO:0060017 5 5 0,000 5,081E-03 0,12867255 ! toxin metabolic process GO:0009404 5 5 0,000 5,081E-03 0,1277664 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 5,081E-03 0,12687293 ! cytokine secretion GO:0050663 5 5 0,000 5,081E-03 0,12599187 ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 5 5 0,000 5,081E-03 0,12512296 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 5,081E-03 0,12426595 ! skeletal myofibril assembly GO:0014866 5 5 0,000 5,081E-03 0,12342061 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 5 0,000 5,081E-03 0,12258669 ! epithelial cell proliferation GO:0050673 5 5 0,000 5,081E-03 0,12176396 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 5 5 0,000 5,081E-03 0,1209522 ! regulation of retroviral genome replication GO:0045091 5 5 0,000 5,081E-03 0,12015119 ! negative regulation of survival gene product expression GO:0008634 5 5 0,000 5,081E-03 0,11936072 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 5,081E-03 0,11858058 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of defense response to virus by host GO:0050691 5 5 0,000 5,081E-03 0,11781058 ! transmembrane-ephrin receptor activity GO:0005005 5 5 0,000 5,081E-03 0,11705051 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 5,081E-03 0,11630019 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 5,081E-03 0,11555942 ! glutamate catabolic process GO:0006538 6 5 0,000 5,081E-03 0,11482803 ! positive regulation of isotype switching to IgG isotypes GO:0048304 9 5 0,000 5,081E-03 0,11410585 ! microvillus organization GO:0032528 5 5 0,000 5,081E-03 0,11339268 GO:0030033|microvillus assembly, ! tyrosine catabolic process GO:0006572 5 5 0,000 5,081E-03 0,11268838 ! L-serine biosynthetic process GO:0006564 5 5 0,000 5,081E-03 0,11199277 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 5,081E-03 0,1113057 ! pericentriolar material GO:0000242 6 5 0,000 5,081E-03 0,11062701 ! polyol biosynthetic process GO:0046173 5 5 0,000 5,081E-03 0,10995654 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 6 5 0,000 5,081E-03 0,10929415 ! platelet-derived growth factor alpha-receptor activity GO:0005018 5 5 0,000 5,081E-03 0,1086397 ! proton-transporting V-type ATPase, V0 domain GO:0033179 5 5 0,000 5,081E-03 0,10799303 ! fibroblast growth factor receptor activity GO:0005007 5 5 0,000 5,081E-03 0,10735402 ! protein-DNA loading ATPase activity GO:0033170 5 5 0,000 5,081E-03 0,10672253 GO:0003689|DNA clamp loader activity, ! insulin-like growth factor receptor activity GO:0005010 5 5 0,000 5,081E-03 0,10609842 ! response to tumor necrosis factor GO:0034612 6 5 0,000 5,081E-03 0,10548157 ! mRNA transcription GO:0009299 6 5 0,000 5,081E-03 0,10487185 ! response to ATP GO:0033198 5 5 0,000 5,081E-03 0,10426913 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 5 5 0,000 5,081E-03 0,10367331 ! adenosine receptor activity, G-protein coupled GO:0001609 5 5 0,000 5,081E-03 0,10308426 ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 5,081E-03 0,10250186 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 5 5 0,000 5,081E-03 0,10192601 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 5,081E-03 0,10135659 ! multivesicular body GO:0005771 5 5 0,000 5,081E-03 0,1007935 ! positive regulation of transporter activity GO:0032411 5 5 0,000 5,081E-03 0,10023663 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 5 5 0,000 5,081E-03 0,09968588 ! forebrain neuron development GO:0021884 6 5 0,000 5,081E-03 0,09914114 ! insulin-like growth factor I binding GO:0031994 5 5 0,000 5,081E-03 0,09860233 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 5 5 0,000 5,081E-03 0,09806935 ! demethylase activity GO:0032451 5 5 0,000 5,081E-03 0,09754209 ! peptidyl-histidine phosphorylation GO:0018106 5 5 0,000 5,081E-03 0,09702048 ! epithelial cell maturation GO:0002070 5 5 0,000 5,081E-03 0,09650441 ! nitric-oxide synthase regulator activity GO:0030235 5 5 0,000 5,081E-03 0,09599381 ! regulation of immunoglobulin secretion GO:0051023 5 5 0,000 5,081E-03 0,09548858 ! zymogen granule GO:0042588 5 5 0,000 5,081E-03 0,09498864 ! guanylate cyclase regulator activity GO:0030249 5 5 0,000 5,081E-03 0,0944939 GO:0010851|cyclase regulator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 5,081E-03 0,0940043 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,081E-03 0,09351974 ! early endosome to late endosome transport GO:0045022 5 5 0,000 5,081E-03 0,09304015 ! positive regulation of translational initiation GO:0045948 5 5 0,000 5,081E-03 0,09256546 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 5,081E-03 0,09209558 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 5,081E-03 0,09163045 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! semaphorin receptor activity GO:0017154 6 5 0,000 5,081E-03 0,09117 ! proteoglycan binding GO:0043394 9 5 0,000 5,081E-03 0,09071415 ! regulation of collagen metabolic process GO:0010712 6 5 0,000 5,081E-03 0,09026283 ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 6 5 0,000 5,081E-03 0,08981599 ! zinc ion homeostasis GO:0055069 5 5 0,000 5,081E-03 0,08937354 GO:0006882|cellular zinc ion homeostasis, ! deoxyribonucleoside metabolic process GO:0009120 6 5 0,000 5,081E-03 0,08893544 ! nucleoside monophosphate catabolic process GO:0009125 5 5 0,000 5,081E-03 0,08850161 ! activated T cell proliferation GO:0050798 6 5 0,000 5,081E-03 0,08807199 ! advanced glycation end-product receptor activity GO:0050785 5 5 0,000 5,081E-03 0,08764652 ! dynein binding GO:0045502 5 5 0,000 5,081E-03 0,08722514 ! regulation of dendrite development GO:0050773 5 5 0,000 5,081E-03 0,0868078 ! cardiac muscle cell development GO:0055013 5 5 0,000 5,081E-03 0,08639443 ! anterograde axon cargo transport GO:0008089 5 5 0,000 5,081E-03 0,08598497 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,081E-03 0,08557938 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 5,081E-03 0,0851776 GO:0003923|GPI-anchor transamidase activity, ! lymphoid progenitor cell differentiation GO:0002320 5 5 0,000 5,081E-03 0,08477958 ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 5,081E-03 0,08438525 ! MutLalpha complex binding GO:0032405 6 5 0,000 5,081E-03 0,08399458 ! sphingomyelin catabolic process GO:0006685 6 5 0,000 5,081E-03 0,08360751 ! high-density lipoprotein binding GO:0008035 5 5 0,000 5,081E-03 0,08322399 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 5,081E-03 0,08284397 ! positive regulation of B cell differentiation GO:0045579 5 5 0,000 5,081E-03 0,08246741 ! regulation of acetylcholine secretion GO:0014056 5 5 0,000 5,081E-03 0,08209425 ! centromeric DNA binding GO:0019237 5 5 0,000 5,081E-03 0,08172446 ! cyclohydrolase activity GO:0019238 5 5 0,000 5,081E-03 0,08135798 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 5,081E-03 0,08099477 ! positive T cell selection GO:0043368 9 5 0,000 5,081E-03 0,0806348 ! neural tube patterning GO:0021532 5 5 0,000 5,081E-03 0,08027801 ! amylase activity GO:0016160 5 5 0,000 5,081E-03 0,07992436 ! metaphase plate congression GO:0051310 5 5 0,000 5,081E-03 0,07957381 ! regulation of sterol transport GO:0032371 5 5 0,000 5,081E-03 0,07922633 GO:0032374|regulation of cholesterol transport, ! sympathetic nervous system development GO:0048485 5 5 0,000 5,081E-03 0,07888187 ! oxygen homeostasis GO:0032364 5 5 0,000 5,081E-03 0,07854039 ! skeletal muscle regeneration GO:0043403 5 5 0,000 5,081E-03 0,07820185 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 5 5 0,000 5,081E-03 0,07786622 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 5 5 0,000 5,081E-03 0,07753346 ! SAP kinase activity GO:0016909 5 5 0,000 5,081E-03 0,07720353 ! positive regulation of pseudopodium assembly GO:0031274 5 5 0,000 5,081E-03 0,0768764 GO:0031272|regulation of pseudopodium assembly, ! phosphatidylserine binding GO:0001786 5 5 0,000 5,081E-03 0,07655202 ! alpha-mannosidase activity GO:0004559 6 5 0,000 5,081E-03 0,07623038 ! alpha-glucosidase activity GO:0004558 6 5 0,000 5,081E-03 0,07591142 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 5,081E-03 0,07559512 ! myeloid dendritic cell activation GO:0001773 5 5 0,000 5,081E-03 0,07528145 GO:0043011|myeloid dendritic cell differentiation, ! anaphase GO:0051322 5 5 0,000 5,081E-03 0,07497037 GO:0000090|mitotic anaphase, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 5,081E-03 0,07466185 ! ribonuclease H activity GO:0004523 5 5 0,000 5,081E-03 0,07435586 ! CARD domain binding GO:0050700 5 5 0,000 5,081E-03 0,07405237 ! regulation of muscle cell apoptosis GO:0010660 5 5 0,000 5,081E-03 0,07375134 ! AP-2 adaptor complex GO:0030122 5 5 0,000 5,081E-03 0,07345275 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 5 5 0,000 5,081E-03 0,07315657 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 5,081E-03 0,07286277 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 5,081E-03 0,07257132 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 5,081E-03 0,07228219 ! negative regulation of macrophage differentiation GO:0045650 5 5 0,000 5,081E-03 0,07199535 ! negative regulation of osteoclast differentiation GO:0045671 5 5 0,000 5,081E-03 0,07171079 ! ceramidase activity GO:0017040 5 5 0,000 5,081E-03 0,07142846 ! negative regulation of osteoblast differentiation GO:0045668 6 5 0,000 5,081E-03 0,07114835 ! GTP-Rho binding GO:0017049 5 5 0,000 5,081E-03 0,07087043 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 5,081E-03 0,07059467 ! chondroitin sulfotransferase activity GO:0034481 5 5 0,000 5,081E-03 0,07032104 ! positive regulation of T-helper 2 cell differentiation GO:0045630 5 5 0,000 5,081E-03 0,07004953 ! alcohol transmembrane transporter activity GO:0015665 5 5 0,000 5,081E-03 0,06978011 GO:0015166|polyol transmembrane transporter activity, ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 5,081E-03 0,06951276 ! TAP complex GO:0042825 5 5 0,000 5,081E-03 0,06924744 ! bHLH transcription factor binding GO:0043425 5 5 0,000 5,081E-03 0,06898414 ! actinin binding GO:0042805 6 5 0,000 5,081E-03 0,06872284 ! secretory granule organization GO:0033363 5 5 0,000 5,081E-03 0,06846351 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 5 5 0,000 5,081E-03 0,06820613 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 5,081E-03 0,06795067 ! striatum development GO:0021756 5 5 0,000 5,081E-03 0,06769712 ! photoreceptor inner segment GO:0001917 5 5 0,000 5,081E-03 0,06744546 ! regulation of T cell mediated cytotoxicity GO:0001914 9 5 0,000 5,081E-03 0,06719566 ! aldehyde-lyase activity GO:0016832 5 5 0,000 5,081E-03 0,06694771 ! regulation of mitochondrial depolarization GO:0051900 5 5 0,000 5,081E-03 0,06670158 ! T cell activation during immune response GO:0002286 5 5 0,000 5,081E-03 0,06645725 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 5,081E-03 0,06621471 ! 1-aminocyclopropane-1-carboxylate synthase activity GO:0016847 5 5 0,000 5,081E-03 0,06597393 ! dystroglycan complex GO:0016011 6 5 0,000 5,081E-03 0,06573489 ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 5 5 0,000 5,081E-03 0,06549758 ! neural plate development GO:0001840 5 5 0,000 5,081E-03 0,06526198 ! toll-like receptor signaling pathway GO:0002224 5 5 0,000 5,081E-03 0,06502806 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 5,081E-03 0,06479582 ! phosphopantetheine binding GO:0031177 5 5 0,000 5,081E-03 0,06456523 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 5,081E-03 0,06433627 ! negative regulation of actin filament bundle formation GO:0032232 8 5 0,000 5,081E-03 0,06410894 GO:0051497|negative regulation of stress fiber formation, ! organ or tissue specific immune response GO:0002251 5 5 0,000 5,081E-03 0,0638832 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 5,081E-03 0,06365905 ! diacylglycerol metabolic process GO:0046339 5 5 0,000 5,081E-03 0,06343647 ! cytoplasmic microtubule organization GO:0031122 5 5 0,000 5,081E-03 0,06321543 ! retina homeostasis GO:0001895 5 5 0,000 5,081E-03 0,06299594 ! release of sequestered calcium ion into cytosol GO:0051209 10 5 0,000 5,081E-03 0,06277796 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 5 5 0,000 5,081E-03 0,06256148 ! regulation of growth hormone secretion GO:0060123 6 5 0,000 5,081E-03 0,06234649 ! collagen type IV GO:0005587 5 5 0,000 5,081E-03 0,06213298 ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 5,081E-03 0,06192092 ! testosterone 17-beta-dehydrogenase (NADP+) activity GO:0047045 5 5 0,000 5,081E-03 0,0617103 ! retrograde protein transport, ER to cytosol GO:0030970 5 5 0,000 5,081E-03 0,06150112 ! spindle assembly GO:0051225 5 5 0,000 5,081E-03 0,06129334 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 5,081E-03 0,06108697 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 5 5 0,000 5,081E-03 0,06088198 GO:0022011|myelination in the peripheral nervous system, ! drug metabolic process GO:0017144 5 5 0,000 5,081E-03 0,06067836 ! protein amino acid prenylation GO:0018346 5 5 0,000 5,081E-03 0,0604761 ! stem cell division GO:0017145 5 5 0,000 5,081E-03 0,06027518 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 5,081E-03 0,06007559 ! phospholipid scrambling GO:0017121 5 5 0,000 5,081E-03 0,05987732 GO:0017128|phospholipid scramblase activity, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 5 5 0,000 5,081E-03 0,05968036 ! regulation of humoral immune response GO:0002920 9 5 0,000 5,081E-03 0,05948469 ! H3/H4 histone acetyltransferase activity GO:0004406 5 5 0,000 5,081E-03 0,05929029 ! regulation of interferon-alpha biosynthetic process GO:0045354 6 5 0,000 5,081E-03 0,05909716 ! negative regulation of protein ubiquitination GO:0031397 5 5 0,000 5,081E-03 0,05890529 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 5,081E-03 0,05871466 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of cAMP biosynthetic process GO:0030819 5 5 0,000 5,081E-03 0,05852526 GO:0030816|positive regulation of cAMP metabolic process, ! phagocytic vesicle GO:0045335 5 5 0,000 5,081E-03 0,05833707 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 5,081E-03 0,05815009 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 5,081E-03 0,05796431 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 5,081E-03 0,05777971 ! polyol transport GO:0015791 6 5 0,000 5,081E-03 0,05759628 ! cell adhesion mediated by integrin GO:0033627 6 5 0,000 5,081E-03 0,05741402 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 5,081E-03 0,0572329 ! glycerol-3-phosphate metabolic process GO:0006072 5 5 0,000 5,081E-03 0,05705292 ! platelet activating factor metabolic process GO:0046469 5 5 0,000 5,081E-03 0,05687407 ! cobalt ion transport GO:0006824 5 5 0,000 5,081E-03 0,05669634 ! response to zinc ion GO:0010043 5 5 0,000 5,081E-03 0,05651972 ! poly(U) RNA binding GO:0008266 5 5 0,000 5,081E-03 0,05634419 ! negative regulation of cell-cell adhesion GO:0022408 5 5 0,000 5,081E-03 0,05616975 ! adaptation of signaling pathway GO:0022401 5 5 0,000 5,081E-03 0,05599639 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! glucocorticoid receptor signaling pathway GO:0042921 5 5 0,000 5,081E-03 0,05582409 GO:0031958|corticosteroid receptor signaling pathway, ! regulation of gluconeogenesis GO:0006111 5 5 0,000 5,081E-03 0,05565285 ! sensory perception of bitter taste GO:0050913 5 5 0,000 5,081E-03 0,05548266 ! regulation of dopamine uptake GO:0051584 5 5 0,000 5,081E-03 0,0553135 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! opsonization GO:0008228 5 5 0,000 5,081E-03 0,05514538 ! protein maturation by protein folding GO:0022417 5 5 0,000 5,081E-03 0,05497827 ! neuron remodeling GO:0016322 6 5 0,000 5,081E-03 0,05481217 ! neurexin binding GO:0042043 5 5 0,000 5,081E-03 0,05464708 ! sensory perception of temperature stimulus GO:0050951 5 5 0,000 5,081E-03 0,05448297 ! regulation of potassium ion transport GO:0043266 5 5 0,000 5,081E-03 0,05431985 ! low-density lipoprotein particle GO:0034362 5 5 0,000 5,081E-03 0,0541577 ! chemoattractant activity GO:0042056 5 5 0,000 5,081E-03 0,05399652 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 6 5 0,000 5,081E-03 0,05383629 ! lipoic acid binding GO:0031405 5 5 0,000 5,081E-03 0,05367701 ! lithium ion binding GO:0031403 6 5 0,000 5,081E-03 0,05351867 ! lipoprotein particle clearance GO:0034381 5 5 0,000 5,081E-03 0,05336126 ! grooming behavior GO:0007625 5 5 0,000 5,081E-03 0,05320478 ! sequestering of actin monomers GO:0042989 5 5 0,000 5,081E-03 0,05304921 ! cobalamin binding GO:0031419 5 5 0,000 5,081E-03 0,05289455 ! retinoic acid binding GO:0001972 5 5 0,000 5,081E-03 0,05274078 ! response to axon injury GO:0048678 5 5 0,000 5,081E-03 0,05258791 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 5,081E-03 0,05243592 ! regulation of activin receptor signaling pathway GO:0032925 5 5 0,000 5,081E-03 0,05228481 ! positive regulation of neurotransmitter secretion GO:0001956 5 5 0,000 5,081E-03 0,05213457 ! mitochondrial genome maintenance GO:0000002 5 5 0,000 5,081E-03 0,05198518 ! protein-lysine 6-oxidase activity GO:0004720 6 5 0,000 5,081E-03 0,05183666 ! female pronucleus GO:0001939 5 5 0,000 5,081E-03 0,05168897 ! F-actin capping protein complex GO:0008290 5 5 0,000 5,081E-03 0,05154213 ! DNA topoisomerase activity GO:0003916 5 5 0,000 5,081E-03 0,05139612 ! poly(ADP-ribose) glycohydrolase activity GO:0004649 6 5 0,000 5,081E-03 0,05125093 ! spinal cord dorsal/ventral patterning GO:0021513 5 5 0,000 5,081E-03 0,05110656 ! dorsal spinal cord development GO:0021516 5 5 0,000 5,081E-03 0,050963 ! ceramide catabolic process GO:0046514 5 5 0,000 5,081E-03 0,05082025 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 5,081E-03 0,05067829 ! neutrophil mediated immunity GO:0002446 5 5 0,000 5,081E-03 0,05053713 ! regulation of oligodendrocyte differentiation GO:0048713 5 5 0,000 5,081E-03 0,05039675 ! Rap GTPase activator activity GO:0046582 5 5 0,000 5,081E-03 0,05025715 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 6 5 0,000 5,081E-03 0,05011831 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 5 5 0,000 5,081E-03 0,04998025 ! positive regulation of filopodium assembly GO:0051491 5 5 0,000 5,081E-03 0,04984294 GO:0051489|regulation of filopodium assembly, ! heart trabecula formation GO:0060347 5 5 0,000 5,081E-03 0,04970638 GO:0060343|trabecula formation, ! amine oxidase activity GO:0008131 6 5 0,000 5,081E-03 0,04957057 ! neutrophil activation GO:0042119 5 5 0,000 5,081E-03 0,0494355 ! regulation of response to food GO:0032095 5 5 0,000 5,081E-03 0,04930117 ! response to food GO:0032094 5 5 0,000 5,081E-03 0,04916756 ! hedgehog receptor activity GO:0008158 5 5 0,000 5,081E-03 0,04903467 ! protein phosphatase 1 binding GO:0008157 5 5 0,000 5,081E-03 0,04890251 ! lipoprotein catabolic process GO:0042159 5 5 0,000 5,081E-03 0,04877105 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 5,081E-03 0,04864029 ! organ growth GO:0035265 7 5 0,000 5,081E-03 0,04851024 ! positive regulation of multicellular organismal metabolic process GO:0044253 6 5 0,000 5,081E-03 0,04838088 ! small-subunit processome GO:0032040 5 5 0,000 5,081E-03 0,04825221 ! UDP-glucosyltransferase activity GO:0035251 5 5 0,000 5,081E-03 0,04812422 ! myosin heavy chain binding GO:0032036 5 5 0,000 5,081E-03 0,0479969 ! nucleoside salvage GO:0043174 7 5 0,000 5,081E-03 0,04787026 GO:0006166|purine ribonucleoside salvage, ! nucleobase transport GO:0015851 5 5 0,000 5,081E-03 0,04774429 ! GPI anchor binding GO:0034235 6 5 0,000 5,081E-03 0,04761897 ! thrombin receptor activity GO:0015057 5 5 0,000 5,081E-03 0,04749432 ! nucleotide-excision repair complex GO:0000109 6 5 0,000 5,081E-03 0,04737031 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 5 5 0,000 5,081E-03 0,04724695 ! dendritic shaft GO:0043198 5 5 0,000 5,081E-03 0,04712423 ! terminal button GO:0043195 8 5 0,000 5,081E-03 0,04700215 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 5,081E-03 0,0468807 GO:0016274|protein-arginine N-methyltransferase activity, ! ferrous iron binding GO:0008198 6 5 0,000 5,081E-03 0,04675987 ! eukaryotic initiation factor 4E binding GO:0008190 5 5 0,000 5,081E-03 0,04663966 ! G2/M transition checkpoint GO:0031576 5 5 0,000 5,081E-03 0,04652008 GO:0031572|G2/M transition DNA damage checkpoint, ! negative regulation of peptide secretion GO:0002792 6 5 0,000 5,081E-03 0,0464011 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 5 5 0,000 5,081E-03 0,04628273 ! response to UV-C GO:0010225 5 5 0,000 5,081E-03 0,04616496 ! carbonyl reductase (NADPH) activity GO:0004090 5 5 0,000 5,081E-03 0,04604779 ! regulation of alpha-beta T cell proliferation GO:0046640 9 5 0,000 5,081E-03 0,04593121 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! positive regulation of organ growth GO:0046622 5 5 0,000 5,081E-03 0,04581523 ! 1-alkyl-2-acetylglycerophosphocholine esterase activity GO:0003847 5 5 0,000 5,081E-03 0,04569982 ! IgE binding GO:0019863 5 5 0,000 5,081E-03 0,045585 ! 3-beta-hydroxy-delta5-steroid dehydrogenase activity GO:0003854 5 5 0,000 5,081E-03 0,04547075 ! monoamine transmembrane transporter activity GO:0008504 5 5 0,000 5,081E-03 0,04535707 ! response to cadmium ion GO:0046686 5 5 0,000 5,081E-03 0,04524396 ! regulation of interleukin-4 production GO:0032673 5 5 0,000 5,081E-03 0,04513142 ! hair follicle maturation GO:0048820 5 5 0,000 5,081E-03 0,04501943 ! regulation of interleukin-10 production GO:0032653 5 5 0,000 5,081E-03 0,04490799 ! ribosomal large subunit biogenesis GO:0042273 5 5 0,000 5,081E-03 0,04479711 ! base conversion or substitution editing GO:0016553 5 5 0,000 5,081E-03 0,04468677 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 5,081E-03 0,04457698 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 5,081E-03 0,04446772 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 5,081E-03 0,044359 GO:0005218|intracellular ligand-gated calcium channel activity, ! general transcriptional repressor activity GO:0016565 5 5 0,000 5,081E-03 0,0442508 ! peroxisome fission GO:0016559 5 5 0,000 5,081E-03 0,04414314 ! alpha-tubulin binding GO:0043014 5 5 0,000 5,081E-03 0,04403599 ! mitotic recombination GO:0006312 5 5 0,000 5,081E-03 0,04392937 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 5,081E-03 0,04382326 ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 5,081E-03 0,04371766 ! positive regulation of chemokine production GO:0032722 5 5 0,000 5,081E-03 0,04361257 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 5,081E-03 0,04350798 ! muscle cell proliferation GO:0033002 5 5 0,000 5,081E-03 0,0434039 ! membrane to membrane docking GO:0022614 5 5 0,000 5,081E-03 0,04330031 ! translation activator activity GO:0008494 5 5 0,000 5,081E-03 0,04319721 ! N-formyl peptide receptor activity GO:0004982 5 5 0,000 5,081E-03 0,04309461 ! coenzyme A biosynthetic process GO:0015937 6 5 0,000 5,081E-03 0,04299249 ! histamine receptor activity GO:0004969 5 5 0,000 5,081E-03 0,04289085 ! dopamine receptor activity GO:0004952 5 5 0,000 5,081E-03 0,04278969 ! galactosidase activity GO:0015925 5 5 0,000 5,081E-03 0,04268901 ! prostaglandin E receptor activity GO:0004957 6 5 0,000 5,081E-03 0,0425888 ! cellular response to nutrient GO:0031670 5 5 0,000 5,081E-03 0,04248906 ! basic amino acid transmembrane transporter activity GO:0015174 5 5 0,000 5,081E-03 0,04238979 ! ATP-gated cation channel activity GO:0004931 7 5 0,000 5,081E-03 0,04229098 ! cytochrome-b5 reductase activity GO:0004128 5 5 0,000 5,081E-03 0,04219263 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 5,081E-03 0,04209473 ! glycine transmembrane transporter activity GO:0015187 5 5 0,000 5,081E-03 0,04199729 ! tyrosine phosphorylation of STAT protein GO:0007260 6 5 0,000 5,081E-03 0,0419003 ! tricarboxylic acid cycle enzyme complex GO:0045239 5 5 0,000 5,081E-03 0,04180375 ! RNA polymerase I transcription factor activity GO:0003701 5 5 0,000 5,081E-03 0,04170765 ! progesterone metabolic process GO:0042448 5 5 0,000 5,081E-03 0,04161199 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 5 5 0,000 5,081E-03 0,04151677 ! disaccharide metabolic process GO:0005984 5 5 0,000 5,081E-03 0,04142198 ! 5'-3' exonuclease activity GO:0008409 5 5 0,000 5,081E-03 0,04132763 ! type II transforming growth factor beta receptor binding GO:0005114 5 5 0,000 5,081E-03 0,0412337 ! histone acetyltransferase binding GO:0035035 5 5 0,000 5,081E-03 0,0411402 ! endosome to lysosome transport GO:0008333 5 5 0,000 5,081E-03 0,04104713 ! glial cell migration GO:0008347 5 5 0,000 5,081E-03 0,04095447 ! S-acyltransferase activity GO:0016417 5 5 0,000 5,081E-03 0,04086223 ! phosphoinositide 3-kinase regulator activity GO:0035014 5 5 0,000 5,081E-03 0,0407704 ! phosphatidylinositol-4-phosphate 3-kinase activity GO:0035005 5 5 0,000 5,081E-03 0,04067899 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 5,081E-03 0,04058799 ! nucleobase transmembrane transporter activity GO:0015205 5 5 0,000 5,081E-03 0,04049739 ! asparaginase activity GO:0004067 5 5 0,000 5,081E-03 0,04040719 ! insemination GO:0007320 5 5 0,000 5,081E-03 0,0403174 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 5,081E-03 0,040228 ! negative regulation of smooth muscle contraction GO:0045986 6 5 0,000 5,081E-03 0,040139 ! aminoacylase activity GO:0004046 5 5 0,000 5,081E-03 0,0400504 ! receptor biosynthetic process GO:0032800 5 5 0,000 5,081E-03 0,03996218 ! penetration of zona pellucida GO:0007341 5 5 0,000 5,081E-03 0,03987435 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 6 5 0,000 5,081E-03 0,03978691 ! aldehyde reductase activity GO:0004032 5 5 0,000 5,081E-03 0,03969985 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 5 0,000 5,081E-03 0,03961316 ! unconventional myosin complex GO:0016461 5 5 0,000 5,081E-03 0,03952686 ! carnitine metabolic process GO:0009437 5 5 0,000 5,081E-03 0,03944093 GO:0006577|betaine metabolic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 6 6 0,000 6,094E-03 0,04720403 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 0,000 6,094E-03 0,04710185 ! regulation of helicase activity GO:0051095 6 6 0,000 6,094E-03 0,04700012 ! testosterone 17-beta-dehydrogenase activity GO:0050327 6 6 0,000 6,094E-03 0,04689883 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 6 6 0,000 6,094E-03 0,04679797 ! tumor necrosis factor-mediated signaling pathway GO:0033209 6 6 0,000 6,094E-03 0,04669754 ! negative regulation of small GTPase mediated signal transduction GO:0051058 7 6 0,000 6,094E-03 0,04659755 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 7 6 0,000 6,094E-03 0,04649798 ! regulation of hormone biosynthetic process GO:0046885 6 6 0,000 6,094E-03 0,04639884 ! ephrin receptor binding GO:0046875 7 6 0,000 6,094E-03 0,04630012 ! biotin binding GO:0009374 7 6 0,000 6,094E-03 0,04620182 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 6,094E-03 0,04610393 ! insulin receptor substrate binding GO:0043560 7 6 0,000 6,094E-03 0,04600646 ! drug:hydrogen antiporter activity GO:0015307 6 6 0,000 6,094E-03 0,0459094 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 6,094E-03 0,04581275 ! carbohydrate phosphorylation GO:0046835 6 6 0,000 6,094E-03 0,0457165 ! regulation of respiratory gaseous exchange GO:0043576 6 6 0,000 6,094E-03 0,04562066 ! neuron adhesion GO:0007158 6 6 0,000 6,094E-03 0,04552522 ! establishment of tissue polarity GO:0007164 7 6 0,000 6,094E-03 0,04543018 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 6 6 0,000 6,094E-03 0,04533553 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 6,094E-03 0,04524128 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 6 0,000 6,094E-03 0,04514742 ! regulation of cardiac muscle cell proliferation GO:0060043 6 6 0,000 6,094E-03 0,04505395 ! positive regulation of receptor-mediated endocytosis GO:0048260 6 6 0,000 6,094E-03 0,04496086 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 6 6 0,000 6,094E-03 0,04486816 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 6,094E-03 0,04477584 ! eukaryotic translation elongation factor 1 complex GO:0005853 6 6 0,000 6,094E-03 0,04468389 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 6,094E-03 0,04459233 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 6 6 0,000 6,094E-03 0,04450114 ! cytoplasmic microtubule GO:0005881 7 6 0,000 6,094E-03 0,04441032 ! Arp2/3 protein complex GO:0005885 7 6 0,000 6,094E-03 0,04431987 ! neurofilament GO:0005883 6 6 0,000 6,094E-03 0,04422979 ! glial cell fate commitment GO:0021781 6 6 0,000 6,094E-03 0,04414007 ! dynactin complex GO:0005869 6 6 0,000 6,094E-03 0,04405072 ! fibroblast growth factor receptor antagonist activity GO:0030353 6 6 0,000 6,094E-03 0,04396173 GO:0005104|fibroblast growth factor receptor binding, GO:0005152|interleukin-1 receptor antagonist activity, ! translation repressor activity GO:0030371 6 6 0,000 6,094E-03 0,0438731 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 6 6 0,000 6,094E-03 0,04378482 ! lipopolysaccharide binding GO:0001530 6 6 0,000 6,094E-03 0,0436969 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 6,094E-03 0,04360933 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 6,094E-03 0,04352211 ! negative regulation of viral genome replication GO:0045071 6 6 0,000 6,094E-03 0,04343524 ! traversing start control point of mitotic cell cycle GO:0007089 6 6 0,000 6,094E-03 0,04334872 ! protein lipoylation GO:0009249 6 6 0,000 6,094E-03 0,04326254 ! cysteine metabolic process GO:0006534 6 6 0,000 6,094E-03 0,0431767 ! regulation of isotype switching to IgG isotypes GO:0048302 10 6 0,000 6,094E-03 0,0430912 ! histidine catabolic process GO:0006548 6 6 0,000 6,094E-03 0,04300604 GO:0009077|histidine family amino acid catabolic process, ! centromeric heterochromatin GO:0005721 6 6 0,000 6,094E-03 0,04292121 ! mitochondrial respiratory chain complex assembly GO:0033108 6 6 0,000 6,094E-03 0,04283672 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 6 6 0,000 6,094E-03 0,04275257 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 6 6 0,000 6,094E-03 0,04266874 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 6 6 0,000 6,094E-03 0,04258524 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 6 0,000 6,094E-03 0,04250206 ! microtubule nucleation GO:0007020 6 6 0,000 6,094E-03 0,04241921 ! proline biosynthetic process GO:0006561 7 6 0,000 6,094E-03 0,04233668 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 6,094E-03 0,04225448 ! transforming growth factor beta receptor activity, type I GO:0005025 6 6 0,000 6,094E-03 0,04217259 ! phasic smooth muscle contraction GO:0014821 6 6 0,000 6,094E-03 0,04209102 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 6,094E-03 0,04200976 ! peptidoglycan metabolic process GO:0000270 6 6 0,000 6,094E-03 0,04192882 GO:0009253|peptidoglycan catabolic process, ! cerebral cortex neuron differentiation GO:0021895 6 6 0,000 6,094E-03 0,04184818 ! paraxial mesoderm development GO:0048339 6 6 0,000 6,094E-03 0,04176786 ! melanosome organization GO:0032438 6 6 0,000 6,094E-03 0,04168785 ! mitochondrial outer membrane translocase complex GO:0005742 6 6 0,000 6,094E-03 0,04160814 ! flotillin complex GO:0016600 6 6 0,000 6,094E-03 0,04152873 ! positive regulation of neuroblast proliferation GO:0002052 6 6 0,000 6,094E-03 0,04144963 ! positive regulation of vasoconstriction GO:0045907 6 6 0,000 6,094E-03 0,04137083 ! negative regulation of DNA recombination GO:0045910 6 6 0,000 6,094E-03 0,04129233 ! positive regulation of exocytosis GO:0045921 7 6 0,000 6,094E-03 0,04121412 ! protein tyrosine kinase activator activity GO:0030296 6 6 0,000 6,094E-03 0,04113621 ! positive regulation of fatty acid metabolic process GO:0045923 6 6 0,000 6,094E-03 0,0410586 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 6,094E-03 0,04098127 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of mitotic cell cycle GO:0045931 6 6 0,000 6,094E-03 0,04090424 ! nonhomologous end joining complex GO:0070419 6 6 0,000 6,094E-03 0,0408275 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! DNA damage response, signal transduction resulting in transcription GO:0042772 9 6 0,000 6,094E-03 0,04075104 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! vinculin binding GO:0017166 6 6 0,000 6,094E-03 0,04067487 ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 6,094E-03 0,04059898 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 6,094E-03 0,04052338 ! sodium ion homeostasis GO:0055078 6 6 0,000 6,094E-03 0,04044806 ! protein heterooligomerization GO:0051291 6 6 0,000 6,094E-03 0,04037302 ! negative regulation of gliogenesis GO:0014014 6 6 0,000 6,094E-03 0,04029825 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 8 6 0,000 6,094E-03 0,04022376 ! translation termination factor activity GO:0008079 6 6 0,000 6,094E-03 0,04014955 GO:0003747|translation release factor activity, ! centrosome duplication GO:0051298 6 6 0,000 6,094E-03 0,04007561 ! astrocyte development GO:0014002 6 6 0,000 6,094E-03 0,04000194 ! protein targeting to lysosome GO:0006622 6 6 0,000 6,094E-03 0,03992854 ! purine base biosynthetic process GO:0009113 7 6 0,000 6,094E-03 0,03985541 ! fibrinolysis GO:0042730 7 6 0,000 6,094E-03 0,03978255 ! peptidyl-asparagine modification GO:0018196 6 6 0,000 6,094E-03 0,03970996 GO:0018279|protein amino acid N-linked glycosylation via asparagine, GO:0004579|dolichyl-diphosphooligosaccharide-protein glycotransferase activity, ! eating behavior GO:0042755 6 6 0,000 6,094E-03 0,03963762 ! B cell lineage commitment GO:0002326 6 6 0,000 6,094E-03 0,03956556 ! thiamin and derivative metabolic process GO:0042723 6 6 0,000 6,094E-03 0,03949375 ! response to exogenous dsRNA GO:0043330 6 6 0,000 6,094E-03 0,0394222 ! enucleate erythrocyte differentiation GO:0043353 6 6 0,000 6,094E-03 0,03935091 ! melanosome transport GO:0032402 6 6 0,000 6,094E-03 0,03927988 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 6 6 0,000 6,094E-03 0,03920911 GO:0014066|regulation of phosphoinositide 3-kinase cascade, ! mast cell activation GO:0045576 6 6 0,000 6,094E-03 0,03913859 ! regulation of dopamine secretion GO:0014059 6 6 0,000 6,094E-03 0,03906832 ! regulation of protein kinase B signaling cascade GO:0051896 6 6 0,000 6,094E-03 0,03899831 ! negative regulation of focal adhesion formation GO:0051895 8 6 0,000 6,094E-03 0,03892854 ! nucleoside catabolic process GO:0009164 7 6 0,000 6,094E-03 0,03885903 ! transcription initiation factor activity GO:0016986 6 6 0,000 6,094E-03 0,03878976 ! negative regulation of T cell differentiation GO:0045581 6 6 0,000 6,094E-03 0,03872074 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 6,094E-03 0,03865196 ! Schwann cell development GO:0014044 6 6 0,000 6,094E-03 0,03858343 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 6 0,000 6,094E-03 0,03851514 ! G-protein coupled photoreceptor activity GO:0008020 6 6 0,000 6,094E-03 0,0384471 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 6,094E-03 0,03837929 ! regulation of chondrocyte differentiation GO:0032330 6 6 0,000 6,094E-03 0,03831172 ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 6,094E-03 0,03824439 ! superoxide-generating NADPH oxidase activity GO:0016175 6 6 0,000 6,094E-03 0,03817729 ! nuclear envelope lumen GO:0005641 6 6 0,000 6,094E-03 0,03811043 ! RNA polymerase II transcription elongation factor activity GO:0016944 7 6 0,000 6,094E-03 0,0380438 ! regulation of meiosis GO:0040020 6 6 0,000 6,094E-03 0,03797741 GO:0051445|regulation of meiotic cell cycle, ! establishment of nucleus localization GO:0040023 8 6 0,000 6,094E-03 0,03791125 ! lipoxygenase activity GO:0016165 6 6 0,000 6,094E-03 0,03784531 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 6,094E-03 0,03777961 ! alpha DNA polymerase:primase complex GO:0005658 7 6 0,000 6,094E-03 0,03771413 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 6,094E-03 0,03764889 ! DNA replication factor C complex GO:0005663 6 6 0,000 6,094E-03 0,03758386 ! nuclear origin of replication recognition complex GO:0005664 6 6 0,000 6,094E-03 0,03751906 GO:0000808|origin recognition complex, ! DNA replication factor A complex GO:0005662 6 6 0,000 6,094E-03 0,03745449 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 6,094E-03 0,03739013 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 6,094E-03 0,037326 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 6,094E-03 0,03726208 ! chromatin silencing complex GO:0005677 6 6 0,000 6,094E-03 0,03719839 GO:0034979|NAD-dependent protein deacetylase activity, GO:0017136|NAD-dependent histone deacetylase activity, ! U12-type spliceosomal complex GO:0005689 7 6 0,000 6,094E-03 0,03713491 ! B cell homeostasis GO:0001782 7 6 0,000 6,094E-03 0,03707165 ! regulation of respiratory burst GO:0060263 6 6 0,000 6,094E-03 0,0370086 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 10 6 0,000 6,094E-03 0,03694577 GO:0002820|negative regulation of adaptive immune response, ! immunological synapse GO:0001772 6 6 0,000 6,094E-03 0,03688315 ! MutLalpha complex GO:0032389 6 6 0,000 6,094E-03 0,03682074 ! leading edge membrane GO:0031256 6 6 0,000 6,094E-03 0,03675854 ! bis(5'-adenosyl)-triphosphatase activity GO:0047710 6 6 0,000 6,094E-03 0,03669655 ! peptidyl-histidine modification GO:0018202 6 6 0,000 6,094E-03 0,03663477 ! exodeoxyribonuclease activity GO:0004529 6 6 0,000 6,094E-03 0,0365732 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! COPII vesicle coat GO:0030127 6 6 0,000 6,094E-03 0,03651184 GO:0012507|ER to Golgi transport vesicle membrane, ! peptidyl-threonine modification GO:0018210 6 6 0,000 6,094E-03 0,03645068 ! diuresis GO:0030146 6 6 0,000 6,094E-03 0,03638973 GO:0030147|natriuresis, ! definitive hemopoiesis GO:0060216 6 6 0,000 6,094E-03 0,03632897 ! glutathione biosynthetic process GO:0006750 6 6 0,000 6,094E-03 0,03626843 ! HLA-B specific inhibitory MHC class I receptor activity GO:0030109 6 6 0,000 6,094E-03 0,03620808 ! BBSome GO:0034464 6 6 0,000 6,094E-03 0,03614793 ! regulation of keratinocyte differentiation GO:0045616 6 6 0,000 6,094E-03 0,03608799 ! glycerophosphodiester phosphodiesterase activity GO:0008889 6 6 0,000 6,094E-03 0,03602824 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 6,094E-03 0,03596869 ! sodium channel regulator activity GO:0017080 6 6 0,000 6,094E-03 0,03590933 ! glycolipid catabolic process GO:0019377 6 6 0,000 6,094E-03 0,03585017 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 6 6 0,000 6,094E-03 0,03579121 ! nicotinamide nucleotide biosynthetic process GO:0019359 6 6 0,000 6,094E-03 0,03573244 ! porphyrin catabolic process GO:0006787 8 6 0,000 6,094E-03 0,03567386 GO:0033015|tetrapyrrole catabolic process, ! removal of superoxide radicals GO:0019430 6 6 0,000 6,094E-03 0,03561548 ! positive regulation of glucose import GO:0046326 7 6 0,000 6,094E-03 0,03555728 GO:0010828|positive regulation of glucose transport, ! triglyceride catabolic process GO:0019433 6 6 0,000 6,094E-03 0,03549928 ! myeloid cell homeostasis GO:0002262 6 6 0,000 6,094E-03 0,03544146 ! lamin binding GO:0005521 6 6 0,000 6,094E-03 0,03538383 ! ectodermal gut morphogenesis GO:0048567 6 6 0,000 6,094E-03 0,03532639 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 6 6 0,000 6,094E-03 0,03526913 ! pattern recognition receptor signaling pathway GO:0002221 6 6 0,000 6,094E-03 0,03521206 ! negative regulation of calcium ion transport GO:0051926 6 6 0,000 6,094E-03 0,03515518 ! peroxiredoxin activity GO:0051920 6 6 0,000 6,094E-03 0,03509848 ! complement binding GO:0001848 8 6 0,000 6,094E-03 0,03504196 ! catecholamine transport GO:0051937 6 6 0,000 6,094E-03 0,03498562 ! regulation of sensory perception GO:0051931 6 6 0,000 6,094E-03 0,03492946 GO:0051930|regulation of sensory perception of pain, ! muscle adaptation GO:0043500 6 6 0,000 6,094E-03 0,03487349 ! hemopoietic progenitor cell differentiation GO:0002244 6 6 0,000 6,094E-03 0,03481769 ! dipeptidase activity GO:0016805 6 6 0,000 6,094E-03 0,03476207 ! ether hydrolase activity GO:0016803 6 6 0,000 6,094E-03 0,03470663 ! FACIT collagen GO:0005593 6 6 0,000 6,094E-03 0,03465136 ! actin filament polymerization GO:0030041 8 6 0,000 6,094E-03 0,03459627 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 6,094E-03 0,03454136 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 6 6 0,000 6,094E-03 0,03448662 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 6 0,000 6,094E-03 0,03443205 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 6,094E-03 0,03437766 ! negative regulation of synaptic transmission GO:0050805 7 6 0,000 6,094E-03 0,03432343 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 6,094E-03 0,03426938 ! organ regeneration GO:0031100 6 6 0,000 6,094E-03 0,0342155 ! Golgi transport complex GO:0017119 6 6 0,000 6,094E-03 0,03416178 ! sheet-forming collagen GO:0030935 6 6 0,000 6,094E-03 0,03410824 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 6,094E-03 0,03405486 ! positive regulation of coagulation GO:0050820 7 6 0,000 6,094E-03 0,03400165 ! defense response to Gram-negative bacterium GO:0050829 6 6 0,000 6,094E-03 0,03394861 ! positive regulation of MHC class II biosynthetic process GO:0045348 6 6 0,000 6,094E-03 0,03389573 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 6 6 0,000 6,094E-03 0,03384301 ! thioredoxin-disulfide reductase activity GO:0004791 6 6 0,000 6,094E-03 0,03379046 ! sphingomyelin phosphodiesterase activity GO:0004767 7 6 0,000 6,094E-03 0,03373807 ! regulation of cGMP metabolic process GO:0030823 6 6 0,000 6,094E-03 0,03368585 ! myoblast cell fate commitment GO:0048625 6 6 0,000 6,094E-03 0,03363378 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 6,094E-03 0,03358188 ! DNA synthesis during DNA repair GO:0000731 7 6 0,000 6,094E-03 0,03353013 ! neutral lipid biosynthetic process GO:0046460 6 6 0,000 6,094E-03 0,03347855 GO:0046463|acylglycerol biosynthetic process, ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 6 6 0,000 6,094E-03 0,03342712 ! nuclear telomere cap complex GO:0000783 6 6 0,000 6,094E-03 0,03337585 GO:0000782|telomere cap complex, ! Golgi to endosome transport GO:0006895 6 6 0,000 6,094E-03 0,03332474 ! negative regulation of JAK-STAT cascade GO:0046426 7 6 0,000 6,094E-03 0,03327379 ! sterol carrier activity GO:0005498 6 6 0,000 6,094E-03 0,03322299 ! positive regulation of cell-cell adhesion GO:0022409 6 6 0,000 6,094E-03 0,03317234 ! succinate metabolic process GO:0006105 6 6 0,000 6,094E-03 0,03312185 ! myelin sheath GO:0043209 6 6 0,000 6,094E-03 0,03307151 ! perikaryon GO:0043204 7 6 0,000 6,094E-03 0,03302133 ! oxaloacetate metabolic process GO:0006107 7 6 0,000 6,094E-03 0,0329713 ! malate metabolic process GO:0006108 6 6 0,000 6,094E-03 0,03292142 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 6 6 0,000 6,094E-03 0,03287169 ! posttranscriptional gene silencing by RNA GO:0035194 6 6 0,000 6,094E-03 0,03282211 GO:0016441|posttranscriptional gene silencing, ! mating behavior GO:0007617 6 6 0,000 6,094E-03 0,03277267 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 6,094E-03 0,03272339 ! rhythmic behavior GO:0007622 7 6 0,000 6,094E-03 0,03267426 ! copulation GO:0007620 6 6 0,000 6,094E-03 0,03262527 ! erythrocyte maturation GO:0043249 6 6 0,000 6,094E-03 0,03257643 ! equilibrioception GO:0050957 6 6 0,000 6,094E-03 0,03252774 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 6,094E-03 0,03247919 ! G-protein coupled receptor kinase activity GO:0004703 6 6 0,000 6,094E-03 0,03243078 ! chemosensory behavior GO:0007635 6 6 0,000 6,094E-03 0,03238252 ! synaptic transmission, dopaminergic GO:0001963 7 6 0,000 6,094E-03 0,03233441 ! mechanosensory behavior GO:0007638 6 6 0,000 6,094E-03 0,03228643 ! response to interferon-gamma GO:0034341 6 6 0,000 6,094E-03 0,0322386 ! spinal cord patterning GO:0021511 6 6 0,000 6,094E-03 0,03219091 ! cGMP-mediated signaling GO:0019934 6 6 0,000 6,094E-03 0,03214336 ! protein geranylgeranyltransferase activity GO:0004661 6 6 0,000 6,094E-03 0,03209595 ! activation of MAPKKK activity GO:0000185 6 6 0,000 6,094E-03 0,03204868 ! nerve growth factor receptor signaling pathway GO:0048011 8 6 0,000 6,094E-03 0,03200155 ! glucosyltransferase activity GO:0046527 6 6 0,000 6,094E-03 0,03195456 ! sphingoid catabolic process GO:0046521 6 6 0,000 6,094E-03 0,03190771 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 6,094E-03 0,03186099 ! activin receptor activity GO:0017002 6 6 0,000 6,094E-03 0,03181441 ! ovulation GO:0030728 6 6 0,000 6,094E-03 0,03176796 ! dopamine binding GO:0035240 7 6 0,000 6,094E-03 0,03172166 ! hyperosmotic response GO:0006972 6 6 0,000 6,094E-03 0,03167548 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 6 0,000 6,094E-03 0,03162944 ! nuclear localization sequence binding GO:0008139 6 6 0,000 6,094E-03 0,03158354 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 6,094E-03 0,03153776 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 6,094E-03 0,03149212 ! copper ion transmembrane transporter activity GO:0005375 6 6 0,000 6,094E-03 0,03144661 ! poly(A) RNA binding GO:0008143 6 6 0,000 6,094E-03 0,03140124 ! positive transcription elongation factor activity GO:0008159 6 6 0,000 6,094E-03 0,03135599 ! regulation of glycogen metabolic process GO:0070873 7 6 0,000 6,094E-03 0,03131087 GO:0032881|regulation of polysaccharide metabolic process, ! maintenance of protein location in nucleus GO:0051457 6 6 0,000 6,094E-03 0,03126588 ! intracellular pH reduction GO:0051452 6 6 0,000 6,094E-03 0,03122103 GO:0045851|pH reduction, ! purine salvage GO:0043101 8 6 0,000 6,094E-03 0,0311763 ! nucleotide-sugar transmembrane transporter activity GO:0005338 6 6 0,000 6,094E-03 0,0311317 ! neurotrophin binding GO:0043121 6 6 0,000 6,094E-03 0,03108722 ! ciliary rootlet GO:0035253 6 6 0,000 6,094E-03 0,03104288 ! neurotransmitter catabolic process GO:0042135 10 6 0,000 6,094E-03 0,03099866 ! ruffle organization GO:0031529 6 6 0,000 6,094E-03 0,03095456 ! T cell mediated immunity GO:0002456 6 6 0,000 6,094E-03 0,03091059 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 7 6 0,000 6,094E-03 0,03086675 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! carnitine transport GO:0015879 6 6 0,000 6,094E-03 0,03082303 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 6,094E-03 0,03077943 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! palmitoyl-CoA hydrolase activity GO:0016290 6 6 0,000 6,094E-03 0,03073595 ! S-methyltransferase activity GO:0008172 6 6 0,000 6,094E-03 0,0306926 ! phospholipase D activity GO:0004630 6 6 0,000 6,094E-03 0,03064937 ! rRNA modification GO:0000154 6 6 0,000 6,094E-03 0,03060627 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 6,094E-03 0,03056328 ! neuronal ion channel clustering GO:0045161 6 6 0,000 6,094E-03 0,03052041 ! response to UV-B GO:0010224 6 6 0,000 6,094E-03 0,03047767 ! interaction with symbiont GO:0051702 6 6 0,000 6,094E-03 0,03043504 ! negative regulation of insulin receptor signaling pathway GO:0046627 6 6 0,000 6,094E-03 0,03039254 ! IgG binding GO:0019864 6 6 0,000 6,094E-03 0,03035015 ! positive regulation of cytokine production during immune response GO:0002720 6 6 0,000 6,094E-03 0,03030788 ! base-excision repair, AP site formation GO:0006285 6 6 0,000 6,094E-03 0,03026572 ! benzodiazepine receptor activity GO:0008503 6 6 0,000 6,094E-03 0,03022369 ! response to copper ion GO:0046688 6 6 0,000 6,094E-03 0,03018177 ! DNA topological change GO:0006265 6 6 0,000 6,094E-03 0,03013997 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 6,094E-03 0,03009828 ! dendrite morphogenesis GO:0048813 6 6 0,000 6,094E-03 0,03005671 ! regulation of interleukin-1 beta production GO:0032651 6 6 0,000 6,094E-03 0,03001525 ! regulation of myeloid cell apoptosis GO:0033032 6 6 0,000 6,094E-03 0,02997391 ! positive regulation of tumor necrosis factor production GO:0032760 6 6 0,000 6,094E-03 0,02993268 ! nucleosome disassembly GO:0006337 6 6 0,000 6,094E-03 0,02989156 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! inositol trisphosphate 3-kinase activity GO:0008440 6 6 0,000 6,094E-03 0,02985056 ! regulation of mast cell activation GO:0033003 6 6 0,000 6,094E-03 0,02980967 ! guanylyltransferase activity GO:0070568 6 6 0,000 6,094E-03 0,02976889 ! receptor internalization GO:0031623 7 6 0,000 6,094E-03 0,02972822 ! neuropeptide Y receptor activity GO:0004983 6 6 0,000 6,094E-03 0,02968766 ! ATP-dependent peptidase activity GO:0004176 6 6 0,000 6,094E-03 0,02964722 ! serine-type carboxypeptidase activity GO:0004185 6 6 0,000 6,094E-03 0,02960688 GO:0070008|serine-type exopeptidase activity, ! protein deubiquitination GO:0016579 6 6 0,000 6,094E-03 0,02956665 ! negative regulation of neuroblast proliferation GO:0007406 6 6 0,000 6,094E-03 0,02952653 ! NuRD complex GO:0016581 6 6 0,000 6,094E-03 0,02948653 ! nucleosome positioning GO:0016584 6 6 0,000 6,094E-03 0,02944663 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 6,094E-03 0,02940683 ! alpha-adrenergic receptor activity GO:0004936 8 6 0,000 6,094E-03 0,02936715 ! glycine binding GO:0016594 8 6 0,000 6,094E-03 0,02932757 ! costamere GO:0043034 7 6 0,000 6,094E-03 0,0292881 ! A band GO:0031672 6 6 0,000 6,094E-03 0,02924873 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 6,094E-03 0,02920947 ! dopamine biosynthetic process GO:0042416 7 6 0,000 6,094E-03 0,02917032 ! procollagen-proline dioxygenase activity GO:0019798 6 6 0,000 6,094E-03 0,02913127 ! negative regulation of axon extension GO:0030517 6 6 0,000 6,094E-03 0,02909232 ! actin monomer binding GO:0003785 6 6 0,000 6,094E-03 0,02905348 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 6,094E-03 0,02901474 ! lysozyme activity GO:0003796 6 6 0,000 6,094E-03 0,02897611 ! regulation of Rac protein signal transduction GO:0035020 6 6 0,000 6,094E-03 0,02893757 ! ATP catabolic process GO:0006200 6 6 0,000 6,094E-03 0,02889914 ! determination of adult lifespan GO:0008340 6 6 0,000 6,094E-03 0,02886082 ! somatic stem cell maintenance GO:0035019 6 6 0,000 6,094E-03 0,02882259 ! negative regulation of organic acid transport GO:0032891 6 6 0,000 6,094E-03 0,02878447 ! establishment of apical/basal cell polarity GO:0035089 6 6 0,000 6,094E-03 0,02874644 ! calcium-dependent phospholipase A2 activity GO:0047498 6 6 0,000 6,094E-03 0,02870852 ! O-acetyltransferase activity GO:0016413 6 6 0,000 6,094E-03 0,02867069 ! CoA-ligase activity GO:0016405 6 6 0,000 6,094E-03 0,02863297 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 6,094E-03 0,02859534 ! IkappaB kinase complex GO:0008385 6 6 0,000 6,094E-03 0,02855782 ! pyrimidine nucleotide catabolic process GO:0006244 6 6 0,000 6,094E-03 0,02852039 ! store-operated calcium channel activity GO:0015279 6 6 0,000 6,094E-03 0,02848306 ! aminomethyltransferase activity GO:0004047 6 6 0,000 6,094E-03 0,02844582 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 6 6 0,000 6,094E-03 0,02840869 ! alkaline phosphatase activity GO:0004035 6 6 0,000 6,094E-03 0,02837165 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 6 6 0,000 6,094E-03 0,02833471 ! oligosaccharide biosynthetic process GO:0009312 7 7 0,000 7,106E-03 0,0329985 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 7,106E-03 0,03295564 ! sleep GO:0030431 7 7 0,000 7,106E-03 0,0329129 ! synaptonemal complex assembly GO:0007130 7 7 0,000 7,106E-03 0,03287026 GO:0070193|synaptonemal complex organization, ! forebrain regionalization GO:0021871 7 7 0,000 7,106E-03 0,03282774 ! cell proliferation in forebrain GO:0021846 7 7 0,000 7,106E-03 0,03278533 ! meiotic prophase I GO:0007128 7 7 0,000 7,106E-03 0,03274302 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 7 0,000 7,106E-03 0,03270083 ! SMAD protein nuclear translocation GO:0007184 8 7 0,000 7,106E-03 0,03265874 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 7 7 0,000 7,106E-03 0,03261676 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 7,106E-03 0,03257489 ! diphosphotransferase activity GO:0016778 8 7 0,000 7,106E-03 0,03253313 ! actin-myosin filament sliding GO:0033275 7 7 0,000 7,106E-03 0,03249148 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! signal peptide processing GO:0006465 7 7 0,000 7,106E-03 0,03244993 ! glycine hydroxymethyltransferase activity GO:0004372 8 7 0,000 7,106E-03 0,03240848 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 7,106E-03 0,03236715 ! macrophage chemotaxis GO:0048246 7 7 0,000 7,106E-03 0,03232591 ! cerebral cortex cell migration GO:0021795 7 7 0,000 7,106E-03 0,03228479 ! tachykinin receptor signaling pathway GO:0007217 7 7 0,000 7,106E-03 0,03224376 ! membrane hyperpolarization GO:0060081 7 7 0,000 7,106E-03 0,03220285 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 7,106E-03 0,03216203 ! enoyl-CoA hydratase activity GO:0004300 7 7 0,000 7,106E-03 0,03212132 ! DNA replication origin binding GO:0003688 7 7 0,000 7,106E-03 0,03208071 ! ATPase binding GO:0051117 7 7 0,000 7,106E-03 0,03204021 ! positive regulation of glycolysis GO:0045821 7 7 0,000 7,106E-03 0,0319998 ! positive regulation of isotype switching GO:0045830 11 7 0,000 7,106E-03 0,0319595 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 8 7 0,000 7,106E-03 0,0319193 ! ribonucleoside triphosphate catabolic process GO:0009203 7 7 0,000 7,106E-03 0,0318792 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! protein-cofactor linkage GO:0018065 7 7 0,000 7,106E-03 0,0318392 ! positive regulation of chemokine biosynthetic process GO:0045080 7 7 0,000 7,106E-03 0,0317993 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 7 7 0,000 7,106E-03 0,0317595 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! thymic T cell selection GO:0045061 11 7 0,000 7,106E-03 0,0317198 ! structural constituent of tooth enamel GO:0030345 7 7 0,000 7,106E-03 0,0316802 ! transepithelial chloride transport GO:0030321 7 7 0,000 7,106E-03 0,0316407 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 7,106E-03 0,0316013 ! glycine catabolic process GO:0006546 7 7 0,000 7,106E-03 0,03156199 GO:0009071|serine family amino acid catabolic process, ! deoxyribonucleotide biosynthetic process GO:0009263 8 7 0,000 7,106E-03 0,03152279 ! cytoskeletal anchoring at plasma membrane GO:0007016 8 7 0,000 7,106E-03 0,03148368 ! response to pH GO:0009268 7 7 0,000 7,106E-03 0,03144466 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 7,106E-03 0,03140575 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! polyamine biosynthetic process GO:0006596 7 7 0,000 7,106E-03 0,03136693 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 7 7 0,000 7,106E-03 0,0313282 ! endosome organization GO:0007032 7 7 0,000 7,106E-03 0,03128957 ! thyroid hormone generation GO:0006590 7 7 0,000 7,106E-03 0,03125104 ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 7,106E-03 0,0312126 GO:0021940|positive regulation of granule cell precursor proliferation, ! reverse cholesterol transport GO:0043691 7 7 0,000 7,106E-03 0,03117425 ! tumor necrosis factor receptor activity GO:0005031 7 7 0,000 7,106E-03 0,031136 ! indolalkylamine metabolic process GO:0006586 7 7 0,000 7,106E-03 0,03109785 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! proton-transporting V-type ATPase, V1 domain GO:0033180 7 7 0,000 7,106E-03 0,03105978 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 7,106E-03 0,03102181 ! retinoid X receptor binding GO:0046965 7 7 0,000 7,106E-03 0,03098394 ! central nervous system neuron axonogenesis GO:0021955 7 7 0,000 7,106E-03 0,03094615 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 7,106E-03 0,03090846 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! regulation of phosphoprotein phosphatase activity GO:0043666 7 7 0,000 7,106E-03 0,03087086 GO:0010921|regulation of phosphatase activity, ! platelet-derived growth factor receptor activity GO:0005017 7 7 0,000 7,106E-03 0,03083335 ! urea metabolic process GO:0019627 7 7 0,000 7,106E-03 0,03079593 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! retinoic acid receptor signaling pathway GO:0048384 7 7 0,000 7,106E-03 0,0307586 ! regulation of type I interferon production GO:0032479 8 7 0,000 7,106E-03 0,03072136 ! peroxisomal matrix GO:0005782 7 7 0,000 7,106E-03 0,03068421 GO:0031907|microbody lumen, ! methyltransferase complex GO:0034708 7 7 0,000 7,106E-03 0,03064715 GO:0035097|histone methyltransferase complex, ! response to dietary excess GO:0002021 7 7 0,000 7,106E-03 0,03061018 ! p53 binding GO:0002039 7 7 0,000 7,106E-03 0,0305733 ! osteoblast development GO:0002076 8 7 0,000 7,106E-03 0,03053651 ! positive regulation of nitric-oxide synthase activity GO:0051000 7 7 0,000 7,106E-03 0,03049981 ! lipid phosphatase activity GO:0042577 7 7 0,000 7,106E-03 0,0304632 ! male sex determination GO:0030238 7 7 0,000 7,106E-03 0,03042667 ! clathrin binding GO:0030276 8 7 0,000 7,106E-03 0,03039023 ! negative regulation of translational initiation GO:0045947 7 7 0,000 7,106E-03 0,03035388 ! determination of anterior/posterior axis, embryo GO:0008595 7 7 0,000 7,106E-03 0,03031761 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 7 7 0,000 7,106E-03 0,03028144 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 7,106E-03 0,03024534 GO:0030204|chondroitin sulfate metabolic process, ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 7,106E-03 0,03020934 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 7,106E-03 0,03017342 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 7,106E-03 0,03013758 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 7,106E-03 0,03010183 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 8 7 0,000 7,106E-03 0,03006616 ! hyaluronan metabolic process GO:0030212 8 7 0,000 7,106E-03 0,03003058 ! protein retention in ER lumen GO:0006621 7 7 0,000 7,106E-03 0,02999509 ! cardiac muscle cell differentiation GO:0055007 7 7 0,000 7,106E-03 0,02995967 ! peptidyl-arginine modification GO:0018195 7 7 0,000 7,106E-03 0,02992434 ! regulation of circadian rhythm GO:0042752 7 7 0,000 7,106E-03 0,0298891 ! Hsp90 protein binding GO:0051879 7 7 0,000 7,106E-03 0,02985393 ! MutSalpha complex binding GO:0032407 8 7 0,000 7,106E-03 0,02981885 ! regulation of fat cell differentiation GO:0045598 7 7 0,000 7,106E-03 0,02978385 ! establishment of melanosome localization GO:0032401 7 7 0,000 7,106E-03 0,02974894 ! regulation of focal adhesion formation GO:0051893 9 7 0,000 7,106E-03 0,0297141 ! gas homeostasis GO:0033483 7 7 0,000 7,106E-03 0,02967935 ! cranial nerve morphogenesis GO:0021602 7 7 0,000 7,106E-03 0,02964468 ! subpallium development GO:0021544 7 7 0,000 7,106E-03 0,02961009 ! laminin-1 complex GO:0005606 7 7 0,000 7,106E-03 0,02957557 GO:0043256|laminin complex, ! molybdopterin cofactor biosynthetic process GO:0032324 7 7 0,000 7,106E-03 0,02954114 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 8 7 0,000 7,106E-03 0,02950679 ! eye photoreceptor cell differentiation GO:0001754 10 7 0,000 7,106E-03 0,02947252 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 7 7 0,000 7,106E-03 0,02943833 ! positive regulation of immunoglobulin mediated immune response GO:0002891 11 7 0,000 7,106E-03 0,02940422 GO:0002714|positive regulation of B cell mediated immunity, ! protein sumoylation GO:0016925 7 7 0,000 7,106E-03 0,02937019 ! establishment of chromosome localization GO:0051303 7 7 0,000 7,106E-03 0,02933623 GO:0050000|chromosome localization, ! regulation of lipid transport GO:0032368 7 7 0,000 7,106E-03 0,02930236 ! regulation of cell division GO:0051302 7 7 0,000 7,106E-03 0,02926856 ! chromatin assembly complex GO:0005678 7 7 0,000 7,106E-03 0,02923484 ! sex chromatin GO:0001739 7 7 0,000 7,106E-03 0,0292012 GO:0000803|sex chromosome, ! oligosaccharyl transferase activity GO:0004576 7 7 0,000 7,106E-03 0,02916764 ! chitinase activity GO:0004568 7 7 0,000 7,106E-03 0,02913415 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 7 7 0,000 7,106E-03 0,02910074 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 7 7 0,000 7,106E-03 0,0290674 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 10 7 0,000 7,106E-03 0,02903415 ! inhibitory MHC class I receptor activity GO:0032396 7 7 0,000 7,106E-03 0,02900096 GO:0030110|HLA-C specific inhibitory MHC class I receptor activity, ! ER to Golgi transport vesicle GO:0030134 7 7 0,000 7,106E-03 0,02896786 ! molybdenum ion binding GO:0030151 7 7 0,000 7,106E-03 0,02893483 ! centriolar satellite GO:0034451 8 7 0,000 7,106E-03 0,02890187 ! positive regulation of epidermis development GO:0045684 7 7 0,000 7,106E-03 0,02886899 ! proteasome regulator activity GO:0010860 7 7 0,000 7,106E-03 0,02883619 ! antibiotic transport GO:0042891 7 7 0,000 7,106E-03 0,02880345 ! negative regulation of transmission of nerve impulse GO:0051970 8 7 0,000 7,106E-03 0,0287708 ! regulation of synaptic transmission, glutamatergic GO:0051966 7 7 0,000 7,106E-03 0,02873821 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 7,106E-03 0,0287057 ! aspartate family amino acid catabolic process GO:0009068 7 7 0,000 7,106E-03 0,02867327 ! Wnt receptor activity GO:0042813 7 7 0,000 7,106E-03 0,02864091 ! regulation of protein homodimerization activity GO:0043496 7 7 0,000 7,106E-03 0,02860862 ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 7 7 0,000 7,106E-03 0,0285764 ! positive regulation of viral reproduction GO:0048524 7 7 0,000 7,106E-03 0,02854426 ! negative regulation of viral reproduction GO:0048525 7 7 0,000 7,106E-03 0,02851218 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 9 7 0,000 7,106E-03 0,02848018 ! blastocyst growth GO:0001832 7 7 0,000 7,106E-03 0,02844825 ! pigment granule transport GO:0051904 7 7 0,000 7,106E-03 0,0284164 ! lymphocyte activation during immune response GO:0002285 7 7 0,000 7,106E-03 0,02838461 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 7,106E-03 0,0283529 ! negative regulation of fibrinolysis GO:0051918 7 7 0,000 7,106E-03 0,02832125 ! negative regulation of telomere maintenance GO:0032205 7 7 0,000 7,106E-03 0,02828968 ! cerebellar cortex formation GO:0021697 8 7 0,000 7,106E-03 0,02825818 ! activation of innate immune response GO:0002218 7 7 0,000 7,106E-03 0,02822674 GO:0002758|innate immune response-activating signal transduction, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 7 7 0,000 7,106E-03 0,02819538 ! natural killer cell mediated immunity GO:0002228 7 7 0,000 7,106E-03 0,02816409 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of synaptic transmission, dopaminergic GO:0032225 7 7 0,000 7,106E-03 0,02813286 ! regulation of synaptic transmission, GABAergic GO:0032228 7 7 0,000 7,106E-03 0,02810171 ! flavin-containing monooxygenase activity GO:0004499 7 7 0,000 7,106E-03 0,02807062 ! regulation of muscle adaptation GO:0043502 7 7 0,000 7,106E-03 0,02803961 ! sequestering of metal ion GO:0051238 7 7 0,000 7,106E-03 0,02800866 ! regulation of T cell receptor signaling pathway GO:0050856 8 7 0,000 7,106E-03 0,02797778 ! membrane attack complex GO:0005579 7 7 0,000 7,106E-03 0,02794696 ! fibrinogen complex GO:0005577 7 7 0,000 7,106E-03 0,02791622 ! septin complex GO:0031105 9 7 0,000 7,106E-03 0,02788554 GO:0032156|septin cytoskeleton, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 7 7 0,000 7,106E-03 0,02785493 ! positive regulation of microtubule polymerization GO:0031116 7 7 0,000 7,106E-03 0,02782439 ! cellular anion homeostasis GO:0030002 7 7 0,000 7,106E-03 0,02779391 GO:0055081|anion homeostasis, ! positive regulation of cyclic nucleotide metabolic process GO:0030801 7 7 0,000 7,106E-03 0,0277635 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! behavioral response to cocaine GO:0048148 9 7 0,000 7,106E-03 0,02773316 ! autophagic vacuole formation GO:0000045 8 7 0,000 7,106E-03 0,02770289 ! negative regulation of smooth muscle cell proliferation GO:0048662 7 7 0,000 7,106E-03 0,02767267 ! translation initiation factor binding GO:0031369 7 7 0,000 7,106E-03 0,02764253 ! regulation of lipid catabolic process GO:0050994 7 7 0,000 7,106E-03 0,02761245 ! activin binding GO:0048185 7 7 0,000 7,106E-03 0,02758244 ! syncytium formation by plasma membrane fusion GO:0000768 7 7 0,000 7,106E-03 0,02755249 GO:0007520|myoblast fusion, ! nucleotide-excision repair, DNA incision GO:0033683 7 7 0,000 7,106E-03 0,02752261 ! oligosaccharyltransferase complex GO:0008250 7 7 0,000 7,106E-03 0,02749279 ! phototransduction, visible light GO:0007603 7 7 0,000 7,106E-03 0,02746303 ! positive regulation of neurotransmitter transport GO:0051590 7 7 0,000 7,106E-03 0,02743334 ! lipoprotein transport GO:0042953 7 7 0,000 7,106E-03 0,02740372 ! cell division site part GO:0032155 7 7 0,000 7,106E-03 0,02737416 GO:0032153|cell division site, ! laminin binding GO:0043236 9 7 0,000 7,106E-03 0,02734466 ! detection of mechanical stimulus involved in sensory perception GO:0050974 7 7 0,000 7,106E-03 0,02731522 ! phospholipid efflux GO:0033700 7 7 0,000 7,106E-03 0,02728585 ! DNA insertion or deletion binding GO:0032135 7 7 0,000 7,106E-03 0,02725654 GO:0032138|single base insertion or deletion binding, ! glucocorticoid metabolic process GO:0008211 7 7 0,000 7,106E-03 0,0272273 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 7 7 0,000 7,106E-03 0,02719812 ! poly-purine tract binding GO:0070717 7 7 0,000 7,106E-03 0,027169 ! T-helper 1 type immune response GO:0042088 7 7 0,000 7,106E-03 0,02713994 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 7,106E-03 0,02711094 GO:0032107|regulation of response to nutrient levels, ! amyloid precursor protein catabolic process GO:0042987 7 7 0,000 7,106E-03 0,02708201 ! leukocyte degranulation GO:0043299 7 7 0,000 7,106E-03 0,02705314 ! bile acid and bile salt transport GO:0015721 7 7 0,000 7,106E-03 0,02702433 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 7,106E-03 0,02699558 ! glycerol ether biosynthetic process GO:0046504 7 7 0,000 7,106E-03 0,02696689 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 7,106E-03 0,02693826 GO:0046513|ceramide biosynthetic process, ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 7,106E-03 0,0269097 ! pigment granule organization GO:0048753 7 7 0,000 7,106E-03 0,02688119 ! eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 7 7 0,000 7,106E-03 0,02685274 ! regulation of interleukin-8 biosynthetic process GO:0045414 8 7 0,000 7,106E-03 0,02682436 ! regulation of pigmentation during development GO:0048070 10 7 0,000 7,106E-03 0,02679603 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 7 7 0,000 7,106E-03 0,02676777 ! macrophage activation GO:0042116 7 7 0,000 7,106E-03 0,02673956 ! positive regulation of activated T cell proliferation GO:0042104 7 7 0,000 7,106E-03 0,02671141 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 7 7 0,000 7,106E-03 0,02668333 ! galactose metabolic process GO:0006012 7 7 0,000 7,106E-03 0,0266553 ! vesicle fusion GO:0006906 7 7 0,000 7,106E-03 0,02662733 ! positive regulation of insulin secretion GO:0032024 7 7 0,000 7,106E-03 0,02659942 ! glycerol ether catabolic process GO:0044269 7 7 0,000 7,106E-03 0,02657156 GO:0046464|acylglycerol catabolic process, ! virus-infected cell apoptosis GO:0006926 7 7 0,000 7,106E-03 0,02654377 ! NuA4 histone acetyltransferase complex GO:0035267 8 7 0,000 7,106E-03 0,02651603 ! nucleoside transmembrane transporter activity GO:0005337 7 7 0,000 7,106E-03 0,02648835 GO:0015858|nucleoside transport, ! regulation of vascular permeability GO:0043114 7 7 0,000 7,106E-03 0,02646073 ! regulation of multicellular organismal metabolic process GO:0044246 8 7 0,000 7,106E-03 0,02643317 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 7,106E-03 0,02640566 ! peptidyl-proline dioxygenase activity GO:0031543 7 7 0,000 7,106E-03 0,02637822 ! inclusion body GO:0016234 7 7 0,000 7,106E-03 0,02635082 ! parturition GO:0007567 7 7 0,000 7,106E-03 0,02632349 ! tRNA methyltransferase activity GO:0008175 7 7 0,000 7,106E-03 0,02629621 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 7 7 0,000 7,106E-03 0,02626899 ! intercalated disc GO:0014704 8 7 0,000 7,106E-03 0,02624182 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 7,106E-03 0,02621471 ! neural nucleus development GO:0048857 7 7 0,000 7,106E-03 0,02618766 ! intermediate filament organization GO:0045109 8 7 0,000 7,106E-03 0,02616066 ! skeletal muscle contraction GO:0003009 7 7 0,000 7,106E-03 0,02613372 ! response to antibiotic GO:0046677 7 7 0,000 7,106E-03 0,02610683 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 7 7 0,000 7,106E-03 0,02608 ! preribosome GO:0030684 7 7 0,000 7,106E-03 0,02605323 ! positive regulation of production of molecular mediator of immune response GO:0002702 7 7 0,000 7,106E-03 0,02602651 ! hydrogen-exporting ATPase activity, phosphorylative mechanism GO:0008553 7 7 0,000 7,106E-03 0,02599984 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 7 7 0,000 7,106E-03 0,02597323 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 7,106E-03 0,02594667 ! regulation of interleukin-1 production GO:0032652 7 7 0,000 7,106E-03 0,02592017 ! phosphofructokinase activity GO:0008443 7 7 0,000 7,106E-03 0,02589372 ! postreplication repair GO:0006301 7 7 0,000 7,106E-03 0,02586732 ! gap junction channel activity GO:0005243 7 7 0,000 7,106E-03 0,02584098 ! transcription from RNA polymerase I promoter GO:0006360 7 7 0,000 7,106E-03 0,02581469 ! mitochondrion morphogenesis GO:0070584 8 7 0,000 7,106E-03 0,02578846 ! transcription termination GO:0006353 8 7 0,000 7,106E-03 0,02576228 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 7 7 0,000 7,106E-03 0,02573615 ! tetracycline transporter activity GO:0008493 7 7 0,000 7,106E-03 0,02571007 GO:0042895|antibiotic transporter activity, ! cytidylyltransferase activity GO:0070567 7 7 0,000 7,106E-03 0,02568405 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 7,106E-03 0,02565808 ! melanocortin receptor activity GO:0004977 7 7 0,000 7,106E-03 0,02563216 ! coenzyme A metabolic process GO:0015936 8 7 0,000 7,106E-03 0,0256063 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 7 0,000 7,106E-03 0,02558049 ! regulation of macrophage activation GO:0043030 7 7 0,000 7,106E-03 0,02555473 ! cytidine deaminase activity GO:0004126 7 7 0,000 7,106E-03 0,02552902 ! inositol trisphosphate kinase activity GO:0051766 7 7 0,000 7,106E-03 0,02550336 ! apical protein localization GO:0045176 7 7 0,000 7,106E-03 0,02547775 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 7,106E-03 0,0254522 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 7,106E-03 0,0254267 ! virion binding GO:0046790 10 7 0,000 7,106E-03 0,02540124 ! nonprotein amino acid metabolic process GO:0019794 7 7 0,000 7,106E-03 0,02537584 ! protein prenyltransferase activity GO:0008318 7 7 0,000 7,106E-03 0,02535049 ! protein modification by small protein removal GO:0070646 7 7 0,000 7,106E-03 0,02532519 ! adult feeding behavior GO:0008343 7 7 0,000 7,106E-03 0,02529994 ! CoA carboxylase activity GO:0016421 7 7 0,000 7,106E-03 0,02527474 ! microtubule basal body GO:0005932 7 7 0,000 7,106E-03 0,02524959 ! positive regulation of NF-kappaB import into nucleus GO:0042346 7 7 0,000 7,106E-03 0,0252245 ! embryonic heart tube development GO:0035050 7 7 0,000 7,106E-03 0,02519945 ! kainate selective glutamate receptor activity GO:0015277 7 7 0,000 7,106E-03 0,02517445 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 7,106E-03 0,0251495 ! positive regulation of smooth muscle contraction GO:0045987 7 7 0,000 7,106E-03 0,0251246 ! rRNA transcription GO:0009303 8 8 0,000 8,117E-03 0,0286718 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 8 8 0,000 8,117E-03 0,02864347 ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 0,000 8,117E-03 0,0286152 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 8,117E-03 0,02858698 ! sodium:hydrogen antiporter activity GO:0015385 8 8 0,000 8,117E-03 0,02855881 GO:0005451|monovalent cation:hydrogen antiporter activity, ! negative regulation of lipid biosynthetic process GO:0051055 9 8 0,000 8,117E-03 0,0285307 ! cation:chloride symporter activity GO:0015377 9 8 0,000 8,117E-03 0,02850265 ! positive regulation of small GTPase mediated signal transduction GO:0051057 8 8 0,000 8,117E-03 0,02847465 GO:0046579|positive regulation of Ras protein signal transduction, ! forebrain neuron differentiation GO:0021879 9 8 0,000 8,117E-03 0,02844671 ! male meiosis GO:0007140 8 8 0,000 8,117E-03 0,02841882 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 8 8 0,000 8,117E-03 0,02839098 ! N-glycan processing GO:0006491 8 8 0,000 8,117E-03 0,0283632 ! regulation of smooth muscle cell migration GO:0014910 9 8 0,000 8,117E-03 0,02833548 ! protein self-association GO:0043621 8 8 0,000 8,117E-03 0,02830781 ! RNA methylation GO:0001510 8 8 0,000 8,117E-03 0,02828019 ! prostaglandin biosynthetic process GO:0001516 9 8 0,000 8,117E-03 0,02825263 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 8 8 0,000 8,117E-03 0,02822512 ! regulation of activated T cell proliferation GO:0046006 8 8 0,000 8,117E-03 0,02819766 ! hexokinase activity GO:0004396 8 8 0,000 8,117E-03 0,02817026 ! neurofilament cytoskeleton GO:0060053 8 8 0,000 8,117E-03 0,02814291 ! guanylate cyclase activity GO:0004383 8 8 0,000 8,117E-03 0,02811561 ! integral to mitochondrial membrane GO:0032592 8 8 0,000 8,117E-03 0,02808837 ! troponin complex GO:0005861 9 8 0,000 8,117E-03 0,02806117 ! smoothened signaling pathway GO:0007224 8 8 0,000 8,117E-03 0,02803404 ! keratinocyte proliferation GO:0043616 8 8 0,000 8,117E-03 0,02800695 ! negative regulation of muscle cell differentiation GO:0051148 8 8 0,000 8,117E-03 0,02797992 ! ganglioside metabolic process GO:0001573 8 8 0,000 8,117E-03 0,02795294 ! reflex GO:0060004 11 8 0,000 8,117E-03 0,02792601 ! small protein activating enzyme activity GO:0008641 10 8 0,000 8,117E-03 0,02789913 ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 8,117E-03 0,0278723 ! hemoglobin metabolic process GO:0020027 8 8 0,000 8,117E-03 0,02784553 ! protein targeting to ER GO:0045047 9 8 0,000 8,117E-03 0,0278188 ! positive regulation of survival gene product expression GO:0045885 8 8 0,000 8,117E-03 0,02779213 ! arginine catabolic process GO:0006527 8 8 0,000 8,117E-03 0,02776551 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 8,117E-03 0,02773894 ! malate dehydrogenase activity GO:0016615 8 8 0,000 8,117E-03 0,02771242 ! inner mitochondrial membrane organization GO:0007007 9 8 0,000 8,117E-03 0,02768595 ! telomere maintenance via telomerase GO:0007004 8 8 0,000 8,117E-03 0,02765954 GO:0010833|telomere maintenance via telomere lengthening, ! DNA secondary structure binding GO:0000217 8 8 0,000 8,117E-03 0,02763317 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 9 8 0,000 8,117E-03 0,02760685 ! proline metabolic process GO:0006560 9 8 0,000 8,117E-03 0,02758058 ! melanosome membrane GO:0033162 10 8 0,000 8,117E-03 0,02755437 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 8,117E-03 0,0275282 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 8,117E-03 0,02750208 ! melanin metabolic process GO:0006582 9 8 0,000 8,117E-03 0,02747601 ! death receptor activity GO:0005035 8 8 0,000 8,117E-03 0,02744999 ! Golgi lumen GO:0005796 8 8 0,000 8,117E-03 0,02742402 ! smooth endoplasmic reticulum GO:0005790 9 8 0,000 8,117E-03 0,0273981 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 8,117E-03 0,02737223 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 9 8 0,000 8,117E-03 0,02734641 GO:0048500|signal recognition particle, ! Golgi cisterna GO:0031985 9 8 0,000 8,117E-03 0,02732063 ! positive regulation of mesenchymal cell proliferation GO:0002053 8 8 0,000 8,117E-03 0,02729491 ! Rac protein signal transduction GO:0016601 8 8 0,000 8,117E-03 0,02726923 ! positive regulation of calcium ion transport into cytosol GO:0010524 11 8 0,000 8,117E-03 0,0272436 ! lens development in camera-type eye GO:0002088 8 8 0,000 8,117E-03 0,02721802 ! positive regulation of vasodilation GO:0045909 8 8 0,000 8,117E-03 0,02719249 ! intestinal cholesterol absorption GO:0030299 8 8 0,000 8,117E-03 0,027167 ! negative regulation of muscle contraction GO:0045932 9 8 0,000 8,117E-03 0,02714157 ! positive regulation vascular endothelial growth factor production GO:0010575 8 8 0,000 8,117E-03 0,02711618 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 8 8 0,000 8,117E-03 0,02709084 ! Schwann cell differentiation GO:0014037 8 8 0,000 8,117E-03 0,02706554 ! sodium:dicarboxylate symporter activity GO:0017153 8 8 0,000 8,117E-03 0,02704029 ! axon guidance receptor activity GO:0008046 8 8 0,000 8,117E-03 0,02701509 ! protein targeting to vacuole GO:0006623 8 8 0,000 8,117E-03 0,02698994 ! response to tropane GO:0014073 10 8 0,000 8,117E-03 0,02696483 GO:0042220|response to cocaine, ! purine nucleoside triphosphate catabolic process GO:0009146 8 8 0,000 8,117E-03 0,02693977 ! melanosome localization GO:0032400 8 8 0,000 8,117E-03 0,02691476 ! response to amine stimulus GO:0014075 10 8 0,000 8,117E-03 0,02688979 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 8 8 0,000 8,117E-03 0,02686487 ! sphingomyelin metabolic process GO:0006684 9 8 0,000 8,117E-03 0,02683999 ! regulation of mitochondrial membrane potential GO:0051881 8 8 0,000 8,117E-03 0,02681517 ! synaptic vesicle endocytosis GO:0048488 8 8 0,000 8,117E-03 0,02679038 ! holo TFIIH complex GO:0005675 8 8 0,000 8,117E-03 0,02676565 ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 8,117E-03 0,02674095 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 8 0,000 8,117E-03 0,02671631 ! negative regulation of cytokine secretion GO:0050710 8 8 0,000 8,117E-03 0,02669171 ! regulation of myoblast differentiation GO:0045661 8 8 0,000 8,117E-03 0,02666715 ! vitamin transporter activity GO:0051183 8 8 0,000 8,117E-03 0,02664264 ! positive regulation of erythrocyte differentiation GO:0045648 8 8 0,000 8,117E-03 0,02661818 ! neuromuscular process controlling posture GO:0050884 8 8 0,000 8,117E-03 0,02659376 ! heparan sulfate sulfotransferase activity GO:0034483 8 8 0,000 8,117E-03 0,02656938 ! regulation of epidermal cell differentiation GO:0045604 8 8 0,000 8,117E-03 0,02654505 ! regulation of T-helper 2 cell differentiation GO:0045628 8 8 0,000 8,117E-03 0,02652076 ! positive regulation of T-helper cell differentiation GO:0045624 8 8 0,000 8,117E-03 0,02649652 ! branched chain family amino acid catabolic process GO:0009083 8 8 0,000 8,117E-03 0,02647232 ! regulation of synaptogenesis GO:0051963 8 8 0,000 8,117E-03 0,02644817 ! oocyte differentiation GO:0009994 8 8 0,000 8,117E-03 0,02642406 GO:0048599|oocyte development, ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 8 8 0,000 8,117E-03 0,02639999 GO:0003756|protein disulfide isomerase activity, ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 8,117E-03 0,02637597 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 8 0,000 8,117E-03 0,02635199 ! beta-1,3-galactosyltransferase activity GO:0048531 8 8 0,000 8,117E-03 0,02632806 ! establishment of pigment granule localization GO:0051905 8 8 0,000 8,117E-03 0,02630417 ! regulation of telomere maintenance GO:0032204 8 8 0,000 8,117E-03 0,02628032 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 8,117E-03 0,02625652 ! amino sugar catabolic process GO:0046348 8 8 0,000 8,117E-03 0,02623275 GO:0006043|glucosamine catabolic process, ! regulation of amino acid transport GO:0051955 8 8 0,000 8,117E-03 0,02620904 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 8,117E-03 0,02618536 ! T cell receptor signaling pathway GO:0050852 13 8 0,000 8,117E-03 0,02616173 ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 8 0,000 8,117E-03 0,02613814 ! cholesterol transporter activity GO:0017127 8 8 0,000 8,117E-03 0,02611459 ! GABA receptor binding GO:0050811 8 8 0,000 8,117E-03 0,02609108 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 8 8 0,000 8,117E-03 0,02606762 ! regulation of microtubule polymerization GO:0031113 8 8 0,000 8,117E-03 0,0260442 ! regulation of developmental growth GO:0048638 8 8 0,000 8,117E-03 0,02602082 ! GMP binding GO:0019002 10 8 0,000 8,117E-03 0,02599748 GO:0030553|cGMP binding, ! regulation of epithelial cell differentiation GO:0030856 8 8 0,000 8,117E-03 0,02597419 ! negative regulation of cellular catabolic process GO:0031330 9 8 0,000 8,117E-03 0,02595093 ! prostate gland development GO:0030850 8 8 0,000 8,117E-03 0,02592772 ! 7S RNA binding GO:0008312 9 8 0,000 8,117E-03 0,02590455 ! neutral lipid catabolic process GO:0046461 8 8 0,000 8,117E-03 0,02588142 ! protein phosphorylated amino acid binding GO:0045309 10 8 0,000 8,117E-03 0,02585834 ! reproductive behavior GO:0019098 8 8 0,000 8,117E-03 0,02583529 ! cell volume homeostasis GO:0006884 9 8 0,000 8,117E-03 0,02581228 ! regulation of long-term neuronal synaptic plasticity GO:0048169 8 8 0,000 8,117E-03 0,02578932 ! oligopeptide transport GO:0006857 8 8 0,000 8,117E-03 0,02576639 GO:0015198|oligopeptide transporter activity, ! induction of positive chemotaxis GO:0050930 8 8 0,000 8,117E-03 0,02574351 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 8,117E-03 0,02572067 ! regulation of dopamine metabolic process GO:0042053 8 8 0,000 8,117E-03 0,02569787 GO:0042069|regulation of catecholamine metabolic process, ! regulation of carbohydrate biosynthetic process GO:0043255 8 8 0,000 8,117E-03 0,02567511 ! titin binding GO:0031432 8 8 0,000 8,117E-03 0,02565238 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 8,117E-03 0,0256297 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 8 0,000 8,117E-03 0,02560706 ! bone resorption GO:0045453 8 8 0,000 8,117E-03 0,02558446 ! glycerolipid catabolic process GO:0046503 8 8 0,000 8,117E-03 0,0255619 ! endoderm development GO:0007492 8 8 0,000 8,117E-03 0,02553938 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 8,117E-03 0,0255169 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 8,117E-03 0,02549445 ! astrocyte differentiation GO:0048708 8 8 0,000 8,117E-03 0,02547205 ! embryonic cranial skeleton morphogenesis GO:0048701 8 8 0,000 8,117E-03 0,02544969 ! syncytium formation GO:0006949 8 8 0,000 8,117E-03 0,02542736 ! embryonic eye morphogenesis GO:0048048 10 8 0,000 8,117E-03 0,02540508 ! B cell proliferation GO:0042100 8 8 0,000 8,117E-03 0,02538283 ! mannose metabolic process GO:0006013 10 8 0,000 8,117E-03 0,02536062 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 8 8 0,000 8,117E-03 0,02533846 ! asymmetric protein localization GO:0008105 8 8 0,000 8,117E-03 0,02531633 ! tumor necrosis factor binding GO:0043120 8 8 0,000 8,117E-03 0,02529424 ! synaptic transmission, glutamatergic GO:0035249 9 8 0,000 8,117E-03 0,02527218 ! neuron apoptosis GO:0051402 8 8 0,000 8,117E-03 0,02525017 ! macroautophagy GO:0016236 9 8 0,000 8,117E-03 0,02522819 ! Cajal body GO:0015030 8 8 0,000 8,117E-03 0,02520626 ! O-methyltransferase activity GO:0008171 9 8 0,000 8,117E-03 0,02518436 ! H4/H2A histone acetyltransferase complex GO:0043189 9 8 0,000 8,117E-03 0,02516249 ! PcG protein complex GO:0031519 8 8 0,000 8,117E-03 0,02514067 ! ferric iron binding GO:0008199 9 8 0,000 8,117E-03 0,02511889 ! spindle checkpoint GO:0031577 8 8 0,000 8,117E-03 0,02509714 ! segment specification GO:0007379 8 8 0,000 8,117E-03 0,02507543 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 8,117E-03 0,02505375 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 8,117E-03 0,02503212 ! cellular extravasation GO:0045123 9 8 0,000 8,117E-03 0,02501052 ! pronucleus GO:0045120 8 8 0,000 8,117E-03 0,02498896 ! regulation of insulin receptor signaling pathway GO:0046626 8 8 0,000 8,117E-03 0,02496744 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 8 8 0,000 8,117E-03 0,02494595 ! Rac GTPase activator activity GO:0030675 9 8 0,000 8,117E-03 0,0249245 ! regulation of DNA repair GO:0006282 8 8 0,000 8,117E-03 0,02490309 ! transcription-coupled nucleotide-excision repair GO:0006283 9 8 0,000 8,117E-03 0,02488171 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 8,117E-03 0,02486037 ! antigen processing and presentation of exogenous antigen GO:0019884 9 8 0,000 8,117E-03 0,02483907 ! DNA ligation GO:0006266 8 8 0,000 8,117E-03 0,0248178 ! regulation of T cell differentiation in the thymus GO:0033081 8 8 0,000 8,117E-03 0,02479657 ! negative regulation of systemic arterial blood pressure GO:0003085 8 8 0,000 8,117E-03 0,02477538 ! multicellular organismal aging GO:0010259 8 8 0,000 8,117E-03 0,02475422 ! erythrocyte development GO:0048821 8 8 0,000 8,117E-03 0,0247331 ! interleukin-1 receptor activity GO:0004908 8 8 0,000 8,117E-03 0,02471202 ! positive regulation of monooxygenase activity GO:0032770 8 8 0,000 8,117E-03 0,02469097 ! protein import into peroxisome matrix GO:0016558 8 8 0,000 8,117E-03 0,02466995 ! gamma-tubulin binding GO:0043015 8 8 0,000 8,117E-03 0,02464897 ! ribosome binding GO:0043022 9 8 0,000 8,117E-03 0,02462803 ! NADPH oxidase complex GO:0043020 8 8 0,000 8,117E-03 0,02460713 ! mRNA polyadenylation GO:0006378 8 8 0,000 8,117E-03 0,02458625 ! sodium:amino acid symporter activity GO:0005283 8 8 0,000 8,117E-03 0,02456542 ! adenylyltransferase activity GO:0070566 8 8 0,000 8,117E-03 0,02454462 ! zymogen activation GO:0031638 8 8 0,000 8,117E-03 0,02452385 ! axonal fasciculation GO:0007413 8 8 0,000 8,117E-03 0,02450312 ! T cell homeostasis GO:0043029 9 8 0,000 8,117E-03 0,02448243 ! negative regulation of nuclear division GO:0051784 8 8 0,000 8,117E-03 0,02446177 GO:0045839|negative regulation of mitosis, ! energy coupled proton transport, against electrochemical gradient GO:0015988 8 8 0,000 8,117E-03 0,02444114 GO:0015991|ATP hydrolysis coupled proton transport, ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 8 8 0,000 8,117E-03 0,02442055 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 8,117E-03 0,02439999 ! thyroid hormone receptor activity GO:0004887 8 8 0,000 8,117E-03 0,02437947 ! wide pore channel activity GO:0022829 8 8 0,000 8,117E-03 0,02435899 ! ligand-regulated transcription factor activity GO:0003706 8 8 0,000 8,117E-03 0,02433853 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 8,117E-03 0,02431812 ! hormone catabolic process GO:0042447 8 8 0,000 8,117E-03 0,02429773 ! positive regulation of ATPase activity GO:0032781 8 8 0,000 8,117E-03 0,02427738 ! biogenic amine catabolic process GO:0042402 11 8 0,000 8,117E-03 0,02425707 ! Notch binding GO:0005112 8 8 0,000 8,117E-03 0,02423678 ! death receptor binding GO:0005123 8 8 0,000 8,117E-03 0,02421654 ! ATPase regulator activity GO:0060590 8 8 0,000 8,117E-03 0,02419632 ! pyrimidine base metabolic process GO:0006206 10 8 0,000 8,117E-03 0,02417614 ! epidermal growth factor receptor binding GO:0005154 9 8 0,000 8,117E-03 0,02415599 ! dihydropyridine-sensitive calcium channel activity GO:0015270 8 8 0,000 8,117E-03 0,02413588 ! calcium-release channel activity GO:0015278 8 8 0,000 8,117E-03 0,0241158 ! tubulin-tyrosine ligase activity GO:0004835 8 8 0,000 8,117E-03 0,02409576 ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 8,117E-03 0,02407574 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 8 8 0,000 8,117E-03 0,02405576 ! nucleus localization GO:0051647 10 8 0,000 8,117E-03 0,02403582 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 8,117E-03 0,0240159 ! negative regulation of immune effector process GO:0002698 12 8 0,000 8,117E-03 0,02399602 ! C-X-C chemokine receptor activity GO:0016494 8 8 0,000 8,117E-03 0,02397617 ! adenosine deaminase activity GO:0004000 8 8 0,000 8,117E-03 0,02395636 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 9 9 0,000 9,128E-03 0,02691586 ! respiratory burst GO:0045730 9 9 0,000 9,128E-03 0,02689366 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 9 9 0,000 9,128E-03 0,02687148 ! telencephalon cell migration GO:0022029 9 9 0,000 9,128E-03 0,02684935 ! 'de novo' posttranslational protein folding GO:0051084 9 9 0,000 9,128E-03 0,02682725 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 9,128E-03 0,02680519 ! cGMP metabolic process GO:0046068 9 9 0,000 9,128E-03 0,02678316 GO:0006182|cGMP biosynthetic process, ! regulation of epidermal growth factor receptor activity GO:0007176 9 9 0,000 9,128E-03 0,02676117 GO:0010469|regulation of receptor activity, ! inositol trisphosphate phosphatase activity GO:0046030 11 9 0,000 9,128E-03 0,02673922 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! axon part GO:0033267 12 9 0,000 9,128E-03 0,0267173 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 9 9 0,000 9,128E-03 0,02669542 ! RNA polyadenylation GO:0043631 9 9 0,000 9,128E-03 0,02667358 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 9 0,000 9,128E-03 0,02665177 ! regulation of receptor-mediated endocytosis GO:0048259 9 9 0,000 9,128E-03 0,02662999 ! artery development GO:0060840 9 9 0,000 9,128E-03 0,02660825 GO:0048844|artery morphogenesis, ! photoreceptor cell development GO:0042461 12 9 0,000 9,128E-03 0,02658655 GO:0046530|photoreceptor cell differentiation, ! microtubule bundle formation GO:0001578 9 9 0,000 9,128E-03 0,02656488 ! middle ear morphogenesis GO:0042474 9 9 0,000 9,128E-03 0,02654325 ! regulation of mesenchymal cell proliferation GO:0010464 9 9 0,000 9,128E-03 0,02652165 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 12 9 0,000 9,128E-03 0,02650009 GO:0046330|positive regulation of JNK cascade, ! positive regulation of heart contraction GO:0045823 10 9 0,000 9,128E-03 0,02647856 ! lung alveolus development GO:0048286 9 9 0,000 9,128E-03 0,02645707 ! ciliary or flagellar motility GO:0001539 9 9 0,000 9,128E-03 0,02643561 ! beta-amyloid binding GO:0001540 10 9 0,000 9,128E-03 0,02641419 ! pathogenesis GO:0009405 9 9 0,000 9,128E-03 0,0263928 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 10 9 0,000 9,128E-03 0,02637145 ! regulated secretory pathway GO:0045055 9 9 0,000 9,128E-03 0,02635013 ! regulation of S phase of mitotic cell cycle GO:0007090 9 9 0,000 9,128E-03 0,02632885 ! estrogen receptor binding GO:0030331 9 9 0,000 9,128E-03 0,0263076 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 10 9 0,000 9,128E-03 0,02628638 ! regulation of defense response to virus by virus GO:0050690 9 9 0,000 9,128E-03 0,0262652 ! histidine metabolic process GO:0006547 9 9 0,000 9,128E-03 0,02624405 GO:0009075|histidine family amino acid metabolic process, ! L-phenylalanine metabolic process GO:0006558 10 9 0,000 9,128E-03 0,02622294 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 9 9 0,000 9,128E-03 0,02620186 GO:0005978|glycogen biosynthetic process, ! V(D)J recombination GO:0033151 9 9 0,000 9,128E-03 0,02618081 ! nucleobase biosynthetic process GO:0046112 11 9 0,000 9,128E-03 0,0261598 ! regulation of Cdc42 protein signal transduction GO:0032489 9 9 0,000 9,128E-03 0,02613882 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of calcium ion transport into cytosol GO:0010522 12 9 0,000 9,128E-03 0,02611788 ! entry into host cell GO:0030260 9 9 0,000 9,128E-03 0,02609697 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 9 9 0,000 9,128E-03 0,02607609 ! regulation of lipoprotein lipase activity GO:0051004 9 9 0,000 9,128E-03 0,02605524 ! retinoic acid metabolic process GO:0042573 9 9 0,000 9,128E-03 0,02603443 ! retinol metabolic process GO:0042572 9 9 0,000 9,128E-03 0,02601366 ! behavioral fear response GO:0001662 9 9 0,000 9,128E-03 0,02599291 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 10 9 0,000 9,128E-03 0,0259722 ! regulation of vascular endothelial growth factor production GO:0010574 9 9 0,000 9,128E-03 0,02595152 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 9 9 0,000 9,128E-03 0,02593088 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! motor axon guidance GO:0008045 9 9 0,000 9,128E-03 0,02591026 ! regulation of gliogenesis GO:0014013 9 9 0,000 9,128E-03 0,02588968 GO:0045685|regulation of glial cell differentiation, ! recycling endosome membrane GO:0055038 10 9 0,000 9,128E-03 0,02586914 ! pigment granule localization GO:0051875 9 9 0,000 9,128E-03 0,02584862 ! platelet-derived growth factor binding GO:0048407 10 9 0,000 9,128E-03 0,02582814 ! glycosphingolipid biosynthetic process GO:0006688 9 9 0,000 9,128E-03 0,02580769 ! nucleoside diphosphate metabolic process GO:0009132 10 9 0,000 9,128E-03 0,02578727 ! phosphoinositide 3-kinase cascade GO:0014065 9 9 0,000 9,128E-03 0,02576689 ! cell wall macromolecule catabolic process GO:0016998 10 9 0,000 9,128E-03 0,02574653 ! purine ribonucleotide catabolic process GO:0009154 9 9 0,000 9,128E-03 0,02572621 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 9 9 0,000 9,128E-03 0,02570592 ! positive regulation of Rho GTPase activity GO:0032321 9 9 0,000 9,128E-03 0,02568567 ! nitric oxide metabolic process GO:0046209 9 9 0,000 9,128E-03 0,02566544 GO:0006809|nitric oxide biosynthetic process, ! mismatch repair complex GO:0032300 9 9 0,000 9,128E-03 0,02564525 ! icosanoid secretion GO:0032309 9 9 0,000 9,128E-03 0,02562509 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 10 9 0,000 9,128E-03 0,02560496 GO:0010092|specification of organ identity, ! retinal ganglion cell axon guidance GO:0031290 9 9 0,000 9,128E-03 0,02558486 ! morphogenesis of a polarized epithelium GO:0001738 9 9 0,000 9,128E-03 0,02556479 ! sterol catabolic process GO:0016127 9 9 0,000 9,128E-03 0,02554476 GO:0006707|cholesterol catabolic process, ! prophase GO:0051324 9 9 0,000 9,128E-03 0,02552475 ! peptidyl-lysine modification GO:0018205 9 9 0,000 9,128E-03 0,02550478 ! pancreatic ribonuclease activity GO:0004522 9 9 0,000 9,128E-03 0,02548484 ! clathrin coat of coated pit GO:0030132 12 9 0,000 9,128E-03 0,02546493 ! SNARE complex GO:0031201 10 9 0,000 9,128E-03 0,02544505 ! ubiquinone metabolic process GO:0006743 10 9 0,000 9,128E-03 0,0254252 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! snRNA binding GO:0017069 9 9 0,000 9,128E-03 0,02540539 ! regulation of macrophage differentiation GO:0045649 9 9 0,000 9,128E-03 0,0253856 ! regulation of osteoclast differentiation GO:0045670 10 9 0,000 9,128E-03 0,02536585 ! positive regulation of neuron differentiation GO:0045666 9 9 0,000 9,128E-03 0,02534612 ! negative regulation of lymphocyte differentiation GO:0045620 9 9 0,000 9,128E-03 0,02532643 ! methionine biosynthetic process GO:0009086 10 9 0,000 9,128E-03 0,02530676 ! peptidoglycan binding GO:0042834 9 9 0,000 9,128E-03 0,02528713 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 9,128E-03 0,02526753 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! pyridine nucleotide biosynthetic process GO:0019363 9 9 0,000 9,128E-03 0,02524796 ! intramolecular transferase activity, phosphotransferases GO:0016868 9 9 0,000 9,128E-03 0,02522841 ! cholesterol efflux GO:0033344 9 9 0,000 9,128E-03 0,0252089 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 9 9 0,000 9,128E-03 0,02518942 ! metalloenzyme inhibitor activity GO:0048551 10 9 0,000 9,128E-03 0,02516997 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! leukocyte mediated cytotoxicity GO:0001909 9 9 0,000 9,128E-03 0,02515055 ! anterior/posterior axis specification GO:0009948 9 9 0,000 9,128E-03 0,02513116 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 9,128E-03 0,0251118 ! detection of calcium ion GO:0005513 10 9 0,000 9,128E-03 0,02509246 ! negative regulation of glucose import GO:0046325 9 9 0,000 9,128E-03 0,02507316 GO:0010829|negative regulation of glucose transport, ! regulation of fibrinolysis GO:0051917 9 9 0,000 9,128E-03 0,02505389 ! trophectodermal cell differentiation GO:0001829 9 9 0,000 9,128E-03 0,02503465 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 9 0,000 9,128E-03 0,02501543 ! hydrolase activity, acting on ether bonds GO:0016801 9 9 0,000 9,128E-03 0,02499625 ! desmosome GO:0030057 9 9 0,000 9,128E-03 0,0249771 ! prepulse inhibition GO:0060134 9 9 0,000 9,128E-03 0,02495797 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 9 0,000 9,128E-03 0,02493888 ! negative regulation of B cell activation GO:0050869 9 9 0,000 9,128E-03 0,02491981 ! anchoring collagen GO:0030934 9 9 0,000 9,128E-03 0,02490077 ! axon extension GO:0048675 10 9 0,000 9,128E-03 0,02488176 ! neuron fate specification GO:0048665 9 9 0,000 9,128E-03 0,02486279 ! positive regulation of glucose metabolic process GO:0010907 9 9 0,000 9,128E-03 0,02484383 ! cortical actin cytoskeleton organization GO:0030866 9 9 0,000 9,128E-03 0,02482491 ! virus-host interaction GO:0019048 13 9 0,000 9,128E-03 0,02480602 ! rough endoplasmic reticulum membrane GO:0030867 9 9 0,000 9,128E-03 0,02478716 ! pentose-phosphate shunt GO:0006098 9 9 0,000 9,128E-03 0,02476832 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 9,128E-03 0,02474951 ! DNA bending activity GO:0008301 9 9 0,000 9,128E-03 0,02473074 ! social behavior GO:0035176 9 9 0,000 9,128E-03 0,02471199 ! secondary active sulfate transmembrane transporter activity GO:0008271 9 9 0,000 9,128E-03 0,02469327 ! dipeptidyl-peptidase activity GO:0008239 11 9 0,000 9,128E-03 0,02467457 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 9,128E-03 0,02465591 ! very-low-density lipoprotein particle GO:0034361 9 9 0,000 9,128E-03 0,02463727 GO:0034385|triglyceride-rich lipoprotein particle, ! high-density lipoprotein particle GO:0034364 9 9 0,000 9,128E-03 0,02461866 ! amyloid precursor protein metabolic process GO:0042982 10 9 0,000 9,128E-03 0,02460008 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 11 9 0,000 9,128E-03 0,02458153 ! blood vessel remodeling GO:0001974 10 9 0,000 9,128E-03 0,02456301 ! C-X-C chemokine binding GO:0019958 9 9 0,000 9,128E-03 0,02454451 ! 3'-5'-exoribonuclease activity GO:0000175 9 9 0,000 9,128E-03 0,02452604 ! exosome (RNase complex) GO:0000178 9 9 0,000 9,128E-03 0,0245076 ! inositol phosphate-mediated signaling GO:0048016 9 9 0,000 9,128E-03 0,02448919 ! DNA N-glycosylase activity GO:0019104 9 9 0,000 9,128E-03 0,0244708 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 9 9 0,000 9,128E-03 0,02445245 GO:0033549|MAP kinase phosphatase activity, ! ER overload response GO:0006983 11 9 0,000 9,128E-03 0,02443412 ! zinc ion transmembrane transporter activity GO:0005385 9 9 0,000 9,128E-03 0,02441581 ! glucose transmembrane transporter activity GO:0005355 9 9 0,000 9,128E-03 0,02439754 ! retrograde transport, endosome to Golgi GO:0042147 10 9 0,000 9,128E-03 0,02437929 ! phagocytosis, engulfment GO:0006911 10 9 0,000 9,128E-03 0,02436107 ! neurotransmitter biosynthetic process GO:0042136 10 9 0,000 9,128E-03 0,02434288 ! carbohydrate phosphatase activity GO:0019203 9 9 0,000 9,128E-03 0,02432471 ! glutathione peroxidase activity GO:0004602 9 9 0,000 9,128E-03 0,02430657 ! acyl-CoA thioesterase activity GO:0016291 9 9 0,000 9,128E-03 0,02428846 ! lysophospholipase activity GO:0004622 9 9 0,000 9,128E-03 0,02427037 ! brain morphogenesis GO:0048854 9 9 0,000 9,128E-03 0,02425231 ! apolipoprotein binding GO:0034185 9 9 0,000 9,128E-03 0,02423428 ! synaptic vesicle membrane GO:0030672 9 9 0,000 9,128E-03 0,02421628 ! RNA-dependent DNA replication GO:0006278 9 9 0,000 9,128E-03 0,0241983 ! positive regulation of systemic arterial blood pressure GO:0003084 10 9 0,000 9,128E-03 0,02418035 ! kinesin binding GO:0019894 9 9 0,000 9,128E-03 0,02416242 ! nucleoside bisphosphate metabolic process GO:0033865 10 9 0,000 9,128E-03 0,02414453 ! renal water homeostasis GO:0003091 9 9 0,000 9,128E-03 0,02412666 ! positive regulation of interleukin-6 production GO:0032755 9 9 0,000 9,128E-03 0,02410881 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 9,128E-03 0,02409099 ! histone methylation GO:0016571 10 9 0,000 9,128E-03 0,0240732 ! mRNA cleavage GO:0006379 9 9 0,000 9,128E-03 0,02405543 ! negative regulation of tumor necrosis factor production GO:0032720 9 9 0,000 9,128E-03 0,02403769 ! regulation of transcription from RNA polymerase III promoter GO:0006359 9 9 0,000 9,128E-03 0,02401998 ! sarcoplasmic reticulum membrane GO:0033017 10 9 0,000 9,128E-03 0,02400229 ! opioid receptor activity GO:0004985 9 9 0,000 9,128E-03 0,02398463 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 9,128E-03 0,02396699 ! salivary gland development GO:0007431 10 9 0,000 9,128E-03 0,02394938 ! glucosidase activity GO:0015926 10 9 0,000 9,128E-03 0,0239318 ! adrenoceptor activity GO:0004935 11 9 0,000 9,128E-03 0,02391424 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 9 9 0,000 9,128E-03 0,02389671 ! positive regulation of leukocyte migration GO:0002687 9 9 0,000 9,128E-03 0,0238792 ! purine base metabolic process GO:0006144 11 9 0,000 9,128E-03 0,02386172 ! mRNA 3'-UTR binding GO:0003730 9 9 0,000 9,128E-03 0,02384427 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 9 9 0,000 9,128E-03 0,02382684 ! receptor inhibitor activity GO:0030547 9 9 0,000 9,128E-03 0,02380943 GO:0048019|receptor antagonist activity, ! negative regulation of BMP signaling pathway GO:0030514 9 9 0,000 9,128E-03 0,02379205 ! ionotropic glutamate receptor complex GO:0008328 11 9 0,000 9,128E-03 0,0237747 ! transforming growth factor beta receptor binding GO:0005160 9 9 0,000 9,128E-03 0,02375737 ! palmitoyltransferase activity GO:0016409 9 9 0,000 9,128E-03 0,02374007 ! arylsulfatase activity GO:0004065 9 9 0,000 9,128E-03 0,02372279 ! phospholipase inhibitor activity GO:0004859 9 9 0,000 9,128E-03 0,02370554 ! behavioral response to nicotine GO:0035095 9 9 0,000 9,128E-03 0,02368831 ! adenylate kinase activity GO:0004017 10 9 0,000 9,128E-03 0,0236711 ! alcohol dehydrogenase (NAD) activity GO:0004022 9 9 0,000 9,128E-03 0,02365393 ! mitochondrion localization GO:0051646 9 9 0,000 9,128E-03 0,02363677 ! localization within membrane GO:0051668 9 9 0,000 9,128E-03 0,02361965 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 10 0,000 0,0101371 0,0262126 ! lipid particle GO:0005811 10 10 0,000 0,0101371 0,02619363 ! myotube differentiation GO:0014902 10 10 0,000 0,0101371 0,02617469 ! generation of neurons in the forebrain GO:0021872 11 10 0,000 0,0101371 0,02615578 ! regulation of cellular amine metabolic process GO:0033238 10 10 0,000 0,0101371 0,02613689 ! synapsis GO:0007129 10 10 0,000 0,0101371 0,02611804 GO:0070192|chromosome organization involved in meiosis, ! filopodium assembly GO:0046847 12 10 0,000 0,0101371 0,02609921 ! UTP metabolic process GO:0046051 10 10 0,000 0,0101371 0,0260804 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 10 10 0,000 0,0101371 0,02606163 ! COPI coating of Golgi vesicle GO:0048205 10 10 0,000 0,0101371 0,02604288 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 10 10 0,000 0,0101371 0,02602415 ! platelet alpha granule membrane GO:0031092 11 10 0,000 0,0101371 0,02600546 ! macromolecule transmembrane transporter activity GO:0022884 10 10 0,000 0,0101371 0,02598679 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! lipoprotein receptor binding GO:0070325 10 10 0,000 0,0101371 0,02596815 GO:0050750|low-density lipoprotein receptor binding, ! thyroid hormone receptor coactivator activity GO:0030375 10 10 0,000 0,0101371 0,02594953 GO:0010861|thyroid hormone receptor activator activity, ! auditory receptor cell differentiation GO:0042491 11 10 0,000 0,0101371 0,02593094 ! regulation of chemokine biosynthetic process GO:0045073 10 10 0,000 0,0101371 0,02591238 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 10 10 0,000 0,0101371 0,02589385 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 0,0101371 0,02587534 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 10 10 0,000 0,0101371 0,02585686 ! nucleotide-sugar metabolic process GO:0009225 11 10 0,000 0,0101371 0,0258384 ! regulation of catecholamine secretion GO:0050433 10 10 0,000 0,0101371 0,02581997 ! melanocyte differentiation GO:0030318 10 10 0,000 0,0101371 0,02580157 GO:0050931|pigment cell differentiation, ! ER-Golgi intermediate compartment membrane GO:0033116 10 10 0,000 0,0101371 0,02578319 ! deoxyribonucleotide catabolic process GO:0009264 10 10 0,000 0,0101371 0,02576484 ! L-serine metabolic process GO:0006563 11 10 0,000 0,0101371 0,02574651 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 10 10 0,000 0,0101371 0,02572821 ! lipase inhibitor activity GO:0055102 10 10 0,000 0,0101371 0,02570994 ! autophagic vacuole GO:0005776 11 10 0,000 0,0101371 0,0256917 ! NAD metabolic process GO:0019674 10 10 0,000 0,0101371 0,02567347 ! stereocilium GO:0032420 10 10 0,000 0,0101371 0,02565528 GO:0032421|stereocilium bundle, ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 0,0101371 0,02563711 ! regulation of sodium ion transport GO:0002028 10 10 0,000 0,0101371 0,02561897 ! forebrain cell migration GO:0021885 10 10 0,000 0,0101371 0,02560085 ! organelle subcompartment GO:0031984 11 10 0,000 0,0101371 0,02558275 ! chondrocyte differentiation GO:0002062 10 10 0,000 0,0101371 0,02556469 ! negative regulation of ossification GO:0030279 10 10 0,000 0,0101371 0,02554665 ! regulation of smoothened signaling pathway GO:0008589 10 10 0,000 0,0101371 0,02552863 ! heparan sulfate proteoglycan metabolic process GO:0030201 10 10 0,000 0,0101371 0,02551064 ! phosphatidylcholine biosynthetic process GO:0006656 12 10 0,000 0,0101371 0,02549267 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 10 10 0,000 0,0101371 0,02547473 ! protein homotetramerization GO:0051289 11 10 0,000 0,0101371 0,02545682 ! regulation of dephosphorylation GO:0035303 12 10 0,000 0,0101371 0,02543893 ! oligodendrocyte development GO:0014003 10 10 0,000 0,0101371 0,02542107 ! positive regulation of phagocytosis GO:0050766 10 10 0,000 0,0101371 0,02540323 ! response to dsRNA GO:0043331 10 10 0,000 0,0101371 0,02538541 ! mismatch repair complex binding GO:0032404 11 10 0,000 0,0101371 0,02536762 ! snRNA metabolic process GO:0016073 10 10 0,000 0,0101371 0,02534986 GO:0016180|snRNA processing, ! cranial nerve development GO:0021545 10 10 0,000 0,0101371 0,02533212 ! fucose catabolic process GO:0019317 11 10 0,000 0,0101371 0,0253144 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 10 10 0,000 0,0101371 0,02529671 ! retinal binding GO:0016918 10 10 0,000 0,0101371 0,02527905 ! leukocyte activation during immune response GO:0002366 10 10 0,000 0,0101371 0,02526141 GO:0002263|cell activation during immune response, ! cerebellum morphogenesis GO:0021587 11 10 0,000 0,0101371 0,02524379 GO:0021696|cerebellar cortex morphogenesis, ! photoreceptor outer segment GO:0001750 10 10 0,000 0,0101371 0,0252262 ! negative regulation of MAPKKK cascade GO:0043409 10 10 0,000 0,0101371 0,02520863 ! regulation of T-helper 2 type immune response GO:0002828 10 10 0,000 0,0101371 0,02519109 ! ribonuclease P activity GO:0004526 10 10 0,000 0,0101371 0,02517357 ! midbrain development GO:0030901 10 10 0,000 0,0101371 0,02515608 ! musculoskeletal movement GO:0050881 10 10 0,000 0,0101371 0,02513861 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 10 10 0,000 0,0101371 0,02512116 ! regulation of T-helper cell differentiation GO:0045622 10 10 0,000 0,0101371 0,02510374 ! fatty-acid ligase activity GO:0015645 10 10 0,000 0,0101371 0,02508635 GO:0004467|long-chain-fatty-acid-CoA ligase activity, ! regulation of mRNA stability GO:0043488 10 10 0,000 0,0101371 0,02506897 ! quaternary ammonium group transport GO:0015697 10 10 0,000 0,0101371 0,02505163 ! regulation of RNA splicing GO:0043484 10 10 0,000 0,0101371 0,0250343 ! embryonic gut development GO:0048566 10 10 0,000 0,0101371 0,025017 ! positive regulation of amine transport GO:0051954 10 10 0,000 0,0101371 0,02499972 ! defense response to Gram-positive bacterium GO:0050830 10 10 0,000 0,0101371 0,02498247 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,0101371 0,02496524 ! lysogeny GO:0030069 10 10 0,000 0,0101371 0,02494803 GO:0019047|provirus integration, ! lamellipodium assembly GO:0030032 11 10 0,000 0,0101371 0,02493085 ! establishment of cell polarity GO:0030010 10 10 0,000 0,0101371 0,02491369 ! regulation of synapse organization GO:0050807 10 10 0,000 0,0101371 0,02489656 ! cell wall macromolecule metabolic process GO:0044036 11 10 0,000 0,0101371 0,02487945 ! acyl-CoA binding GO:0000062 10 10 0,000 0,0101371 0,02486236 ! negative regulation of muscle development GO:0048635 11 10 0,000 0,0101371 0,0248453 GO:0045843|negative regulation of striated muscle development, ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 0,0101371 0,02482826 ! GDP binding GO:0019003 10 10 0,000 0,0101371 0,02481124 ! photoreceptor activity GO:0009881 10 10 0,000 0,0101371 0,02479425 ! somatic diversification of immune receptors via somatic mutation GO:0002566 10 10 0,000 0,0101371 0,02477727 GO:0016446|somatic hypermutation of immunoglobulin genes, ! cortical cytoskeleton organization GO:0030865 10 10 0,000 0,0101371 0,02476033 ! nitric-oxide synthase binding GO:0050998 11 10 0,000 0,0101371 0,0247434 ! nuclear chromosome, telomeric region GO:0000784 10 10 0,000 0,0101371 0,0247265 ! nucleotidase activity GO:0008252 10 10 0,000 0,0101371 0,02470962 ! detection of mechanical stimulus GO:0050982 10 10 0,000 0,0101371 0,02469277 ! protein complex disassembly GO:0043241 11 10 0,000 0,0101371 0,02467594 GO:0043624|cellular protein complex disassembly, ! androgen metabolic process GO:0008209 10 10 0,000 0,0101371 0,02465913 ! lateral plasma membrane GO:0016328 10 10 0,000 0,0101371 0,02464234 ! estrogen metabolic process GO:0008210 10 10 0,000 0,0101371 0,02462558 ! nucleocytoplasmic transporter activity GO:0005487 10 10 0,000 0,0101371 0,02460884 ! retinol dehydrogenase activity GO:0004745 10 10 0,000 0,0101371 0,02459212 ! negative regulation of cell-matrix adhesion GO:0001953 12 10 0,000 0,0101371 0,02457542 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 11 10 0,000 0,0101371 0,02455875 ! interleukin-1 binding GO:0019966 10 10 0,000 0,0101371 0,0245421 ! endothelial cell differentiation GO:0045446 10 10 0,000 0,0101371 0,02452547 ! cullin-RING ubiquitin ligase complex GO:0031461 10 10 0,000 0,0101371 0,02450887 ! acid phosphatase activity GO:0003993 10 10 0,000 0,0101371 0,02449229 ! regulation of stress fiber formation GO:0051492 13 10 0,000 0,0101371 0,02447573 ! sodium:potassium-exchanging ATPase activity GO:0005391 11 10 0,000 0,0101371 0,02445919 ! calcium-transporting ATPase activity GO:0005388 12 10 0,000 0,0101371 0,02444267 ! telomeric DNA binding GO:0042162 11 10 0,000 0,0101371 0,02442618 ! regulation of intracellular pH GO:0051453 10 10 0,000 0,0101371 0,02440971 ! lipid digestion GO:0044241 10 10 0,000 0,0101371 0,02439326 ! multicellular organism growth GO:0035264 10 10 0,000 0,0101371 0,02437683 ! receptor clustering GO:0043113 10 10 0,000 0,0101371 0,02436043 ! L-glutamate transmembrane transporter activity GO:0005313 10 10 0,000 0,0101371 0,02434405 GO:0015172|acidic amino acid transmembrane transporter activity, ! brush border membrane GO:0031526 11 10 0,000 0,0101371 0,02432769 ! adult heart development GO:0007512 12 10 0,000 0,0101371 0,02431135 ! actin cytoskeleton reorganization GO:0031532 12 10 0,000 0,0101371 0,02429503 ! signalosome GO:0008180 10 10 0,000 0,0101371 0,02427874 ! prefoldin complex GO:0016272 10 10 0,000 0,0101371 0,02426247 ! neuromuscular junction GO:0031594 10 10 0,000 0,0101371 0,02424621 ! regulation of bone resorption GO:0045124 11 10 0,000 0,0101371 0,02422999 ! positive regulation of peptide secretion GO:0002793 10 10 0,000 0,0101371 0,02421378 ! alpha-beta T cell differentiation GO:0046632 11 10 0,000 0,0101371 0,02419759 ! negative regulation of myeloid leukocyte differentiation GO:0002762 10 10 0,000 0,0101371 0,02418143 ! positive regulation of T cell mediated immunity GO:0002711 14 10 0,000 0,0101371 0,02416529 ! taste receptor activity GO:0008527 10 10 0,000 0,0101371 0,02414916 ! Ran GTPase binding GO:0008536 10 10 0,000 0,0101371 0,02413307 ! endocytic vesicle membrane GO:0030666 10 10 0,000 0,0101371 0,02411699 ! regulation of interleukin-12 production GO:0032655 10 10 0,000 0,0101371 0,02410093 ! ribosome assembly GO:0042255 10 10 0,000 0,0101371 0,0240849 ! DNA methylation GO:0006306 12 10 0,000 0,0101371 0,02406888 GO:0006305|DNA alkylation, ! protein-hormone receptor activity GO:0016500 10 10 0,000 0,0101371 0,02405289 ! bile acid transmembrane transporter activity GO:0015125 10 10 0,000 0,0101371 0,02403692 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 13 10 0,000 0,0101371 0,02402097 ! prostaglandin receptor activity GO:0004955 11 10 0,000 0,0101371 0,02400504 ! regulation of isotype switching GO:0045191 14 10 0,000 0,0101371 0,02398913 ! peptide transporter activity GO:0015197 10 10 0,000 0,0101371 0,02397324 ! regulation of leukocyte migration GO:0002685 10 10 0,000 0,0101371 0,02395738 ! retinoid-X receptor activity GO:0004886 10 10 0,000 0,0101371 0,02394153 ! GTPase inhibitor activity GO:0005095 10 10 0,000 0,0101371 0,02392571 ! pattern recognition receptor activity GO:0008329 10 10 0,000 0,0101371 0,02390991 ! gamma-tubulin complex GO:0000930 12 10 0,000 0,0101371 0,02389412 ! germ cell migration GO:0008354 10 10 0,000 0,0101371 0,02387836 ! regulation of organic acid transport GO:0032890 10 10 0,000 0,0101371 0,02386262 ! negative regulation of mast cell proliferation GO:0070667 10 10 0,000 0,0101371 0,0238469 GO:0042130|negative regulation of T cell proliferation, ! cardiac cell differentiation GO:0035051 11 10 0,000 0,0101371 0,0238312 ! amiloride-sensitive sodium channel activity GO:0015280 10 10 0,000 0,0101371 0,02381553 ! sterol transporter activity GO:0015248 10 10 0,000 0,0101371 0,02379987 ! regulation of embryonic development GO:0045995 11 10 0,000 0,0101371 0,02378423 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 11 11 0,000 0,01114552 0,02613307 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 11 0,000 0,01114552 0,02611592 ! negative regulation of blood pressure GO:0045776 11 11 0,000 0,01114552 0,02609879 ! RNA cap binding GO:0000339 12 11 0,000 0,01114552 0,02608169 ! CTP metabolic process GO:0046036 12 11 0,000 0,01114552 0,02606461 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 11 0,000 0,01114552 0,02604755 ! response to pain GO:0048265 11 11 0,000 0,01114552 0,02603052 ! axonemal dynein complex GO:0005858 11 11 0,000 0,01114552 0,0260135 ! eukaryotic translation initiation factor 3 complex GO:0005852 11 11 0,000 0,01114552 0,02599651 ! dopamine receptor signaling pathway GO:0007212 13 11 0,000 0,01114552 0,02597954 ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 11 0,000 0,01114552 0,0259626 ! endocrine pancreas development GO:0031018 11 11 0,000 0,01114552 0,02594567 ! regulation of interferon-gamma biosynthetic process GO:0045072 12 11 0,000 0,01114552 0,02592877 ! regulation of exit from mitosis GO:0007096 11 11 0,000 0,01114552 0,02591189 ! chylomicron GO:0042627 11 11 0,000 0,01114552 0,02589503 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 11 11 0,000 0,01114552 0,02587819 ! glycolipid biosynthetic process GO:0009247 11 11 0,000 0,01114552 0,02586138 ! transforming growth factor beta binding GO:0050431 11 11 0,000 0,01114552 0,02584458 ! glutamate metabolic process GO:0006536 12 11 0,000 0,01114552 0,02582781 ! ribonucleotide catabolic process GO:0009261 11 11 0,000 0,01114552 0,02581106 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 0,01114552 0,02579433 ! vascular endothelial growth factor receptor activity GO:0005021 11 11 0,000 0,01114552 0,02577763 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 11 11 0,000 0,01114552 0,02576094 GO:0045125|bioactive lipid receptor activity, ! Rac GTPase binding GO:0048365 11 11 0,000 0,01114552 0,02574428 ! epithelial cell development GO:0002064 11 11 0,000 0,01114552 0,02572764 ! filamentous actin GO:0031941 11 11 0,000 0,01114552 0,02571102 ! temperature homeostasis GO:0001659 11 11 0,000 0,01114552 0,02569442 ! structural constituent of epidermis GO:0030280 13 11 0,000 0,01114552 0,02567784 ! protein targeting to peroxisome GO:0006625 11 11 0,000 0,01114552 0,02566129 ! spectrin GO:0008091 11 11 0,000 0,01114552 0,02564475 ! cytoskeletal adaptor activity GO:0008093 14 11 0,000 0,01114552 0,02562824 ! negative regulation of axonogenesis GO:0050771 13 11 0,000 0,01114552 0,02561175 ! regulation of phagocytosis GO:0050764 11 11 0,000 0,01114552 0,02559528 ! nucleoside triphosphate catabolic process GO:0009143 11 11 0,000 0,01114552 0,02557883 ! synaptic vesicle exocytosis GO:0016079 12 11 0,000 0,01114552 0,0255624 ! regulation of B cell differentiation GO:0045577 15 11 0,000 0,01114552 0,02554599 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 11 11 0,000 0,01114552 0,02552961 ! basal lamina GO:0005605 12 11 0,000 0,01114552 0,02551324 ! gastrulation with mouth forming second GO:0001702 12 11 0,000 0,01114552 0,0254969 ! spinal cord motor neuron differentiation GO:0021522 11 11 0,000 0,01114552 0,02548058 ! hindbrain morphogenesis GO:0021575 13 11 0,000 0,01114552 0,02546427 ! regulation of hormone metabolic process GO:0032350 12 11 0,000 0,01114552 0,02544799 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 11 0,000 0,01114552 0,02543173 GO:0050706|regulation of interleukin-1 beta secretion, ! COPI vesicle coat GO:0030126 11 11 0,000 0,01114552 0,02541549 GO:0030663|COPI coated vesicle membrane, ! clathrin coat of trans-Golgi network vesicle GO:0030130 14 11 0,000 0,01114552 0,02539927 ! tRNA-specific ribonuclease activity GO:0004549 11 11 0,000 0,01114552 0,02538307 ! cofactor transporter activity GO:0051184 11 11 0,000 0,01114552 0,02536689 ! cobalt ion binding GO:0050897 11 11 0,000 0,01114552 0,02535074 ! pseudouridine synthase activity GO:0009982 12 11 0,000 0,01114552 0,0253346 ! aromatic amino acid family catabolic process GO:0009074 12 11 0,000 0,01114552 0,02531848 ! serine family amino acid biosynthetic process GO:0009070 11 11 0,000 0,01114552 0,02530239 ! histone deacetylase binding GO:0042826 11 11 0,000 0,01114552 0,02528631 ! thymus development GO:0048538 12 11 0,000 0,01114552 0,02527026 ! spleen development GO:0048536 12 11 0,000 0,01114552 0,02525422 ! regulation of RNA stability GO:0043487 11 11 0,000 0,01114552 0,02523821 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 12 11 0,000 0,01114552 0,02522222 ! acid-thiol ligase activity GO:0016878 11 11 0,000 0,01114552 0,02520624 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 11 11 0,000 0,01114552 0,02519029 ! blastocyst formation GO:0001825 11 11 0,000 0,01114552 0,02517436 ! cerebellar cortex development GO:0021695 12 11 0,000 0,01114552 0,02515844 ! regulation of actin filament bundle formation GO:0032231 14 11 0,000 0,01114552 0,02514255 ! ADP binding GO:0043531 11 11 0,000 0,01114552 0,02512668 ! folic acid binding GO:0005542 11 11 0,000 0,01114552 0,02511083 ! FK506 binding GO:0005528 11 11 0,000 0,01114552 0,02509499 GO:0005527|macrolide binding, ! defense response to fungus GO:0050832 11 11 0,000 0,01114552 0,02507918 ! extracellular matrix binding GO:0050840 13 11 0,000 0,01114552 0,02506339 ! microspike assembly GO:0030035 13 11 0,000 0,01114552 0,02504761 ! cytoplasmic sequestering of protein GO:0051220 11 11 0,000 0,01114552 0,02503186 ! regulation of synapse structure and activity GO:0050803 11 11 0,000 0,01114552 0,02501613 ! organ formation GO:0048645 12 11 0,000 0,01114552 0,02500041 ! positive regulation of B cell proliferation GO:0030890 15 11 0,000 0,01114552 0,02498472 ! embryonic hindlimb morphogenesis GO:0035116 11 11 0,000 0,01114552 0,02496905 ! embryonic forelimb morphogenesis GO:0035115 11 11 0,000 0,01114552 0,02495339 ! cellular copper ion homeostasis GO:0006878 12 11 0,000 0,01114552 0,02493776 ! glycosaminoglycan catabolic process GO:0006027 11 11 0,000 0,01114552 0,02492214 ! Golgi vesicle budding GO:0048194 11 11 0,000 0,01114552 0,02490654 ! regulation of positive chemotaxis GO:0050926 11 11 0,000 0,01114552 0,02489097 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 11 11 0,000 0,01114552 0,02487541 ! ion channel inhibitor activity GO:0008200 13 11 0,000 0,01114552 0,02485987 GO:0016248|channel inhibitor activity, ! positive regulation of transcription factor import into nucleus GO:0042993 12 11 0,000 0,01114552 0,02484436 ! MAP kinase kinase activity GO:0004708 11 11 0,000 0,01114552 0,02482886 GO:0004712|protein serine/threonine/tyrosine kinase activity, ! cation:amino acid symporter activity GO:0005416 11 11 0,000 0,01114552 0,02481338 ! mannosyltransferase activity GO:0000030 11 11 0,000 0,01114552 0,02479792 ! cAMP-dependent protein kinase activity GO:0004691 11 11 0,000 0,01114552 0,02478248 ! FMN binding GO:0010181 11 11 0,000 0,01114552 0,02476706 ! response to X-ray GO:0010165 12 11 0,000 0,01114552 0,02475165 ! focal adhesion formation GO:0048041 13 11 0,000 0,01114552 0,02473627 ! actin polymerization or depolymerization GO:0008154 13 11 0,000 0,01114552 0,02472091 ! substrate-bound cell migration GO:0006929 11 11 0,000 0,01114552 0,02470556 ! integrator complex GO:0032039 11 11 0,000 0,01114552 0,02469023 ! UV protection GO:0009650 11 11 0,000 0,01114552 0,02467493 ! L-glutamate transport GO:0015813 11 11 0,000 0,01114552 0,02465964 GO:0015800|acidic amino acid transport, ! retinol binding GO:0019841 11 11 0,000 0,01114552 0,02464437 ! regulation of organ growth GO:0046620 12 11 0,000 0,01114552 0,02462912 ! regulation of cytokine production during immune response GO:0002718 11 11 0,000 0,01114552 0,02461389 ! regulation of T cell mediated immunity GO:0002709 15 11 0,000 0,01114552 0,02459868 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 11 11 0,000 0,01114552 0,02458348 ! regulation of interleukin-8 production GO:0032677 12 11 0,000 0,01114552 0,02456831 ! cyclin-dependent protein kinase regulator activity GO:0016538 11 11 0,000 0,01114552 0,02455315 ! histone acetylation GO:0016573 11 11 0,000 0,01114552 0,02453801 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 12 11 0,000 0,01114552 0,02452289 ! delayed rectifier potassium channel activity GO:0005251 11 11 0,000 0,01114552 0,02450779 ! organic cation transmembrane transporter activity GO:0015101 11 11 0,000 0,01114552 0,02449271 ! chromatin silencing GO:0006342 11 11 0,000 0,01114552 0,02447765 ! gland morphogenesis GO:0022612 12 11 0,000 0,01114552 0,0244626 ! sulfate transmembrane transporter activity GO:0015116 11 11 0,000 0,01114552 0,02444758 ! hexose transmembrane transporter activity GO:0015149 11 11 0,000 0,01114552 0,02443257 ! icosanoid receptor activity GO:0004953 12 11 0,000 0,01114552 0,02441758 GO:0004954|prostanoid receptor activity, ! non-G-protein coupled 7TM receptor activity GO:0004926 12 11 0,000 0,01114552 0,02440261 ! negative regulation of neurological system process GO:0031645 12 11 0,000 0,01114552 0,02438766 ! acid secretion GO:0046717 11 11 0,000 0,01114552 0,02437272 ! nitric oxide mediated signal transduction GO:0007263 11 11 0,000 0,01114552 0,02435781 ! thyroid hormone metabolic process GO:0042403 11 11 0,000 0,01114552 0,02434291 ! quinone cofactor metabolic process GO:0042375 12 11 0,000 0,01114552 0,02432803 ! insulin-like growth factor receptor binding GO:0005159 12 11 0,000 0,01114552 0,02431317 ! midbody GO:0030496 11 11 0,000 0,01114552 0,02429833 ! interferon-alpha/beta receptor binding GO:0005132 11 11 0,000 0,01114552 0,0242835 ! cAMP-dependent protein kinase complex GO:0005952 11 11 0,000 0,01114552 0,02426869 ! water channel activity GO:0015250 11 11 0,000 0,01114552 0,02425391 ! response to nicotine GO:0035094 11 11 0,000 0,01114552 0,02423913 ! response to cold GO:0009409 11 11 0,000 0,01114552 0,02422438 ! adenylate cyclase activity GO:0004016 11 11 0,000 0,01114552 0,02420965 ! 'de novo' protein folding GO:0006458 12 12 0,000 0,01215298 0,02638194 ! centriole GO:0005814 12 12 0,000 0,01215298 0,02636591 ! organellar large ribosomal subunit GO:0000315 13 12 0,000 0,01215298 0,02634991 GO:0005762|mitochondrial large ribosomal subunit, ! cadmium ion binding GO:0046870 13 12 0,000 0,01215298 0,02633392 ! folic acid and derivative biosynthetic process GO:0009396 12 12 0,000 0,01215298 0,02631795 ! bone remodeling GO:0046849 12 12 0,000 0,01215298 0,026302 ! peroxisomal transport GO:0043574 12 12 0,000 0,01215298 0,02628607 ! retina development in camera-type eye GO:0060041 13 12 0,000 0,01215298 0,02627015 ! hair follicle morphogenesis GO:0031069 12 12 0,000 0,01215298 0,02625426 ! voltage-gated sodium channel complex GO:0001518 13 12 0,000 0,01215298 0,02623839 GO:0034706|sodium channel complex, ! regulation of excitatory postsynaptic membrane potential GO:0060079 14 12 0,000 0,01215298 0,02622253 ! hippocampus development GO:0021766 12 12 0,000 0,01215298 0,0262067 ! negative regulation of lipid metabolic process GO:0045833 13 12 0,000 0,01215298 0,02619088 ! T cell selection GO:0045058 16 12 0,000 0,01215298 0,02617509 ! cation:cation antiporter activity GO:0015491 12 12 0,000 0,01215298 0,02615931 ! induction of apoptosis via death domain receptors GO:0008625 12 12 0,000 0,01215298 0,02614355 ! T-tubule GO:0030315 13 12 0,000 0,01215298 0,02612781 ! methionine metabolic process GO:0006555 13 12 0,000 0,01215298 0,02611209 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 14 12 0,000 0,01215298 0,02609639 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! peptide antigen binding GO:0042605 12 12 0,000 0,01215298 0,02608071 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 0,01215298 0,02606504 ! cell-cell junction assembly GO:0007043 12 12 0,000 0,01215298 0,0260494 ! mitotic spindle organization GO:0007052 12 12 0,000 0,01215298 0,02603377 ! fear response GO:0042596 12 12 0,000 0,01215298 0,02601816 ! negative regulation of mitotic cell cycle GO:0045930 13 12 0,000 0,01215298 0,02600257 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 0,01215298 0,025987 ! copper ion homeostasis GO:0055070 13 12 0,000 0,01215298 0,02597145 ! lipoprotein receptor activity GO:0030228 12 12 0,000 0,01215298 0,02595592 ! axon cargo transport GO:0008088 12 12 0,000 0,01215298 0,0259404 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 13 12 0,000 0,01215298 0,02592491 ! transcription elongation factor complex GO:0008023 13 12 0,000 0,01215298 0,02590943 ! positive regulation of Ras GTPase activity GO:0032320 12 12 0,000 0,01215298 0,02589397 ! nuclear outer membrane GO:0005640 12 12 0,000 0,01215298 0,02587853 ! beta-tubulin binding GO:0048487 12 12 0,000 0,01215298 0,02586311 ! autonomic nervous system development GO:0048483 12 12 0,000 0,01215298 0,0258477 ! positive regulation of interleukin-1 secretion GO:0050716 12 12 0,000 0,01215298 0,02583232 GO:0050704|regulation of interleukin-1 secretion, ! exoribonuclease activity GO:0004532 12 12 0,000 0,01215298 0,02581695 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! cofactor transport GO:0051181 12 12 0,000 0,01215298 0,0258016 ! regulation of epidermis development GO:0045682 12 12 0,000 0,01215298 0,02578627 ! protein-chromophore linkage GO:0018298 12 12 0,000 0,01215298 0,02577096 ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 12 12 0,000 0,01215298 0,02575566 ! cell killing GO:0001906 12 12 0,000 0,01215298 0,02574039 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 12 0,000 0,01215298 0,02572513 ! lymphocyte homeostasis GO:0002260 14 12 0,000 0,01215298 0,02570989 ! regulation of fatty acid oxidation GO:0046320 13 12 0,000 0,01215298 0,02569467 ! detection of bacterium GO:0016045 13 12 0,000 0,01215298 0,02567946 ! positive regulation of neuron apoptosis GO:0043525 12 12 0,000 0,01215298 0,02566428 ! dystrophin-associated glycoprotein complex GO:0016010 14 12 0,000 0,01215298 0,02564911 ! internal side of plasma membrane GO:0009898 14 12 0,000 0,01215298 0,02563396 ! RNA 3'-end processing GO:0031123 12 12 0,000 0,01215298 0,02561883 ! developmental induction GO:0031128 13 12 0,000 0,01215298 0,02560371 GO:0045168|cell-cell signaling involved in cell fate specification, ! fibrillar collagen GO:0005583 13 12 0,000 0,01215298 0,02558862 ! positive regulation of calcium-mediated signaling GO:0050850 14 12 0,000 0,01215298 0,02557354 ! inner ear receptor cell differentiation GO:0060113 13 12 0,000 0,01215298 0,02555848 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 0,01215298 0,02554343 ! very-long-chain fatty acid metabolic process GO:0000038 12 12 0,000 0,01215298 0,02552841 ! negative regulation of cell projection organization GO:0031345 14 12 0,000 0,01215298 0,0255134 ! thyroid gland development GO:0030878 12 12 0,000 0,01215298 0,02549841 ! non-recombinational repair GO:0000726 12 12 0,000 0,01215298 0,02548344 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 12 12 0,000 0,01215298 0,02546848 ! lipid localization GO:0010876 12 12 0,000 0,01215298 0,02545354 GO:0019915|lipid storage, ! regulation of glycolysis GO:0006110 12 12 0,000 0,01215298 0,02543862 ! response to cAMP GO:0051591 12 12 0,000 0,01215298 0,02542372 ! negative regulation of transcription factor import into nucleus GO:0042992 12 12 0,000 0,01215298 0,02540884 ! T cell proliferation GO:0042098 17 12 0,000 0,01215298 0,02539397 ! negative regulation of protein amino acid phosphorylation GO:0001933 16 12 0,000 0,01215298 0,02537912 ! receptor signaling protein tyrosine kinase activity GO:0004716 13 12 0,000 0,01215298 0,02536429 ! two-component signal transduction system (phosphorelay) GO:0000160 13 12 0,000 0,01215298 0,02534947 ! peptide or protein amino-terminal blocking GO:0018409 13 12 0,000 0,01215298 0,02533467 ! drug transport GO:0015893 12 12 0,000 0,01215298 0,02531989 ! GTP-dependent protein binding GO:0030742 12 12 0,000 0,01215298 0,02530513 ! regulation of interleukin-6 biosynthetic process GO:0045408 12 12 0,000 0,01215298 0,02529038 ! T cell receptor complex GO:0042101 12 12 0,000 0,01215298 0,02527565 ! membrane protein proteolysis GO:0033619 13 12 0,000 0,01215298 0,02526094 GO:0006509|membrane protein ectodomain proteolysis, ! negative regulation of caspase activity GO:0043154 12 12 0,000 0,01215298 0,02524624 ! protein disulfide oxidoreductase activity GO:0015035 12 12 0,000 0,01215298 0,02523157 ! histone acetyltransferase complex GO:0000123 13 12 0,000 0,01215298 0,02521691 ! dendritic spine GO:0043197 12 12 0,000 0,01215298 0,02520226 ! ATP-binding cassette (ABC) transporter complex GO:0043190 12 12 0,000 0,01215298 0,02518763 ! alpha-beta T cell activation GO:0046631 13 12 0,000 0,01215298 0,02517302 ! organic anion transmembrane transporter activity GO:0008514 13 12 0,000 0,01215298 0,02515843 ! vasoconstriction GO:0042310 13 12 0,000 0,01215298 0,02514386 ! DNA unwinding during replication GO:0006268 12 12 0,000 0,01215298 0,0251293 ! cellular amino acid derivative catabolic process GO:0042219 16 12 0,000 0,01215298 0,02511475 ! mRNA splice site selection GO:0006376 13 12 0,000 0,01215298 0,02510023 ! trans-Golgi network transport vesicle membrane GO:0012510 15 12 0,000 0,01215298 0,02508572 ! ubiquitin protein ligase binding GO:0031625 12 12 0,000 0,01215298 0,02507123 ! monosaccharide transmembrane transporter activity GO:0015145 12 12 0,000 0,01215298 0,02505675 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 12 12 0,000 0,01215298 0,02504229 ! hexosaminidase activity GO:0015929 12 12 0,000 0,01215298 0,02502785 ! diacylglycerol kinase activity GO:0004143 13 12 0,000 0,01215298 0,02501343 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 0,01215298 0,02499902 ! activation of NF-kappaB-inducing kinase activity GO:0007250 12 12 0,000 0,01215298 0,02498463 ! protein kinase C binding GO:0005080 13 12 0,000 0,01215298 0,02497025 ! catecholamine biosynthetic process GO:0042423 13 12 0,000 0,01215298 0,02495589 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 15 12 0,000 0,01215298 0,02494155 ! establishment or maintenance of apical/basal cell polarity GO:0035088 12 12 0,000 0,01215298 0,02492722 ! L-fucose metabolic process GO:0042354 14 12 0,000 0,01215298 0,02491291 ! acylglycerol O-acyltransferase activity GO:0016411 12 12 0,000 0,01215298 0,02489862 ! C-acyltransferase activity GO:0016408 12 12 0,000 0,01215298 0,02488434 ! steroid hydroxylase activity GO:0008395 12 12 0,000 0,01215298 0,02487008 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01215298 0,02485584 ! calcium-activated potassium channel activity GO:0015269 14 12 0,000 0,01215298 0,02484161 ! SWI/SNF-type complex GO:0070603 13 12 0,000 0,01215298 0,0248274 GO:0016514|SWI/SNF complex, ! cilium part GO:0044441 12 12 0,000 0,01215298 0,0248132 ! positive regulation of translation GO:0045727 13 13 0,000 0,01315948 0,02685286 ! ER-associated protein catabolic process GO:0030433 13 13 0,000 0,01315948 0,02683753 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01315948 0,02682221 ! superoxide anion generation GO:0042554 13 13 0,000 0,01315948 0,02680691 ! pteridine and derivative biosynthetic process GO:0042559 14 13 0,000 0,01315948 0,02679162 ! cis-Golgi network GO:0005801 14 13 0,000 0,01315948 0,02677636 ! regulation of S phase GO:0033261 17 13 0,000 0,01315948 0,02676111 ! regulation of chemokine production GO:0032642 13 13 0,000 0,01315948 0,02674588 ! phospholipid catabolic process GO:0009395 14 13 0,000 0,01315948 0,02673066 ! positive regulation of GTPase activity GO:0043547 14 13 0,000 0,01315948 0,02671547 ! endothelial cell migration GO:0043542 13 13 0,000 0,01315948 0,02670029 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 13 13 0,000 0,01315948 0,02668513 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01315948 0,02666998 ! cartilage condensation GO:0001502 14 13 0,000 0,01315948 0,02665485 ! organelle fusion GO:0048284 14 13 0,000 0,01315948 0,02663974 ! positive regulation of lipid metabolic process GO:0045834 13 13 0,000 0,01315948 0,02662465 ! pseudouridine synthesis GO:0001522 14 13 0,000 0,01315948 0,02660957 ! negative regulation of gene expression, epigenetic GO:0045814 13 13 0,000 0,01315948 0,02659452 ! positive regulation of cell growth GO:0030307 13 13 0,000 0,01315948 0,02657947 ! regulation of interleukin-2 biosynthetic process GO:0045076 13 13 0,000 0,01315948 0,02656445 ! negative regulation of proteolysis GO:0045861 13 13 0,000 0,01315948 0,02654944 ! regulation of mRNA processing GO:0050684 13 13 0,000 0,01315948 0,02653445 ! arginine metabolic process GO:0006525 13 13 0,000 0,01315948 0,02651947 ! WW domain binding GO:0050699 14 13 0,000 0,01315948 0,02650452 ! cholesterol binding GO:0015485 13 13 0,000 0,01315948 0,02648958 ! negative regulation of microtubule depolymerization GO:0007026 15 13 0,000 0,01315948 0,02647465 GO:0031114|regulation of microtubule depolymerization, ! Golgi organization GO:0007030 16 13 0,000 0,01315948 0,02645975 ! negative regulation of endothelial cell migration GO:0010596 13 13 0,000 0,01315948 0,02644486 ! integral to peroxisomal membrane GO:0005779 13 13 0,000 0,01315948 0,02642998 GO:0031231|intrinsic to peroxisomal membrane, ! integral to membrane of membrane fraction GO:0000299 14 13 0,000 0,01315948 0,02641513 ! regulation of heart rate GO:0002027 14 13 0,000 0,01315948 0,02640029 ! positive regulation of carbohydrate metabolic process GO:0045913 14 13 0,000 0,01315948 0,02638546 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 14 13 0,000 0,01315948 0,02637066 ! negative regulation of immune response GO:0050777 17 13 0,000 0,01315948 0,02635587 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 13 0,000 0,01315948 0,02634109 ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01315948 0,02632634 ! response to estradiol stimulus GO:0032355 14 13 0,000 0,01315948 0,02631159 ! anaphase-promoting complex GO:0005680 13 13 0,000 0,01315948 0,02629687 ! nucleotide diphosphatase activity GO:0004551 13 13 0,000 0,01315948 0,02628216 ! NADP metabolic process GO:0006739 13 13 0,000 0,01315948 0,02626747 ! regulation of erythrocyte differentiation GO:0045646 13 13 0,000 0,01315948 0,0262528 ! intestinal absorption GO:0050892 13 13 0,000 0,01315948 0,02623814 ! eukaryotic cell surface binding GO:0043499 14 13 0,000 0,01315948 0,0262235 ! digestive tract morphogenesis GO:0048546 13 13 0,000 0,01315948 0,02620887 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 14 13 0,000 0,01315948 0,02619426 ! regulation of cellular carbohydrate catabolic process GO:0043471 14 13 0,000 0,01315948 0,02617967 GO:0043470|regulation of carbohydrate catabolic process, ! tropomyosin binding GO:0005523 13 13 0,000 0,01315948 0,02616509 ! carbon-sulfur lyase activity GO:0016846 13 13 0,000 0,01315948 0,02615053 ! embryonic placenta development GO:0001892 13 13 0,000 0,01315948 0,02613599 ! positive regulation of protein polymerization GO:0032273 13 13 0,000 0,01315948 0,02612146 ! insulin secretion GO:0030073 13 13 0,000 0,01315948 0,02610695 ! regulation of protein ubiquitination GO:0031396 13 13 0,000 0,01315948 0,02609245 ! positive regulation of cellular catabolic process GO:0031331 14 13 0,000 0,01315948 0,02607797 ! G1 phase of mitotic cell cycle GO:0000080 13 13 0,000 0,01315948 0,02606351 ! replisome GO:0030894 14 13 0,000 0,01315948 0,02604906 GO:0043601|nuclear replisome, ! regulation of nitric-oxide synthase activity GO:0050999 13 13 0,000 0,01315948 0,02603463 ! double-strand break repair via homologous recombination GO:0000724 13 13 0,000 0,01315948 0,02602022 GO:0000725|recombinational repair, ! copper ion transport GO:0006825 13 13 0,000 0,01315948 0,02600582 ! regulation of cell-cell adhesion GO:0022407 13 13 0,000 0,01315948 0,02599143 ! forelimb morphogenesis GO:0035136 13 13 0,000 0,01315948 0,02597706 ! mating GO:0007618 13 13 0,000 0,01315948 0,02596271 ! phosphatidylinositol phosphate kinase activity GO:0016307 14 13 0,000 0,01315948 0,02594838 ! MAP kinase activity GO:0004707 14 13 0,000 0,01315948 0,02593406 ! cytokine biosynthetic process GO:0042089 13 13 0,000 0,01315948 0,02591975 ! ventral spinal cord development GO:0021517 13 13 0,000 0,01315948 0,02590546 ! prenyltransferase activity GO:0004659 14 13 0,000 0,01315948 0,02589119 ! platelet-derived growth factor receptor signaling pathway GO:0048008 15 13 0,000 0,01315948 0,02587693 ! regulation of skeletal muscle fiber development GO:0048742 13 13 0,000 0,01315948 0,02586269 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 15 13 0,000 0,01315948 0,02584846 ! protein kinase C activity GO:0004697 15 13 0,000 0,01315948 0,02583425 ! oligodendrocyte differentiation GO:0048709 13 13 0,000 0,01315948 0,02582006 ! water transporter activity GO:0005372 13 13 0,000 0,01315948 0,02580588 ! exocrine system development GO:0035272 14 13 0,000 0,01315948 0,02579172 ! dicarboxylic acid transmembrane transporter activity GO:0005310 13 13 0,000 0,01315948 0,02577757 ! monoamine transport GO:0015844 13 13 0,000 0,01315948 0,02576344 ! CoA hydrolase activity GO:0016289 13 13 0,000 0,01315948 0,02574932 ! embryo implantation GO:0007566 13 13 0,000 0,01315948 0,02573522 ! positive regulation of alpha-beta T cell differentiation GO:0046638 13 13 0,000 0,01315948 0,02572113 ! immunoglobulin binding GO:0019865 13 13 0,000 0,01315948 0,02570706 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,01315948 0,02569301 ! anchored to plasma membrane GO:0046658 14 13 0,000 0,01315948 0,02567897 ! MHC class I protein binding GO:0042288 13 13 0,000 0,01315948 0,02566494 ! histone deacetylation GO:0016575 13 13 0,000 0,01315948 0,02565093 ! calcium channel regulator activity GO:0005246 14 13 0,000 0,01315948 0,02563694 ! neuroblast proliferation GO:0007405 13 13 0,000 0,01315948 0,02562296 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01315948 0,025609 ! response to gamma radiation GO:0010332 13 13 0,000 0,01315948 0,02559505 ! sarcomere organization GO:0045214 13 13 0,000 0,01315948 0,02558112 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 15 13 0,000 0,01315948 0,0255672 ! cAMP binding GO:0030552 13 13 0,000 0,01315948 0,02555329 ! fucosyltransferase activity GO:0008417 14 13 0,000 0,01315948 0,02553941 ! cilium assembly GO:0042384 13 13 0,000 0,01315948 0,02552553 ! negative regulation of leukocyte proliferation GO:0070664 13 13 0,000 0,01315948 0,02551168 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! bacterial binding GO:0008367 13 13 0,000 0,01315948 0,02549783 ! regulation of NF-kappaB import into nucleus GO:0042345 13 13 0,000 0,01315948 0,02548401 ! acrosome reaction GO:0007340 13 13 0,000 0,01315948 0,02547019 ! microtubule-based flagellum GO:0009434 13 13 0,000 0,01315948 0,0254564 ! nucleolar part GO:0044452 13 13 0,000 0,01315948 0,02544261 ! axoneme part GO:0044447 13 13 0,000 0,01315948 0,02542885 ! tRNA modification GO:0006400 14 14 0,000 0,01416503 0,02735711 ! positive regulation of blood pressure GO:0045777 15 14 0,000 0,01416503 0,02734233 ! transferase activity, transferring amino-acyl groups GO:0016755 14 14 0,000 0,01416503 0,02732756 ! negative regulation of bone remodeling GO:0046851 14 14 0,000 0,01416503 0,0273128 ! 2'-deoxyribonucleotide metabolic process GO:0009394 15 14 0,000 0,01416503 0,02729806 GO:0019692|deoxyribose phosphate metabolic process, ! transcription from RNA polymerase III promoter GO:0006383 14 14 0,000 0,01416503 0,02728334 ! guanylate kinase activity GO:0004385 16 14 0,000 0,01416503 0,02726863 ! striated muscle thin filament GO:0005865 15 14 0,000 0,01416503 0,02725394 ! patterning of blood vessels GO:0001569 14 14 0,000 0,01416503 0,02723926 ! mechanoreceptor differentiation GO:0042490 15 14 0,000 0,01416503 0,0272246 ! palate development GO:0060021 15 14 0,000 0,01416503 0,02720995 ! centrosome cycle GO:0007098 14 14 0,000 0,01416503 0,02719533 ! regulation of defense response to virus GO:0050688 14 14 0,000 0,01416503 0,02718071 ! cAMP-dependent protein kinase regulator activity GO:0008603 14 14 0,000 0,01416503 0,02716611 ! ephrin receptor activity GO:0005003 16 14 0,000 0,01416503 0,02715153 ! protein polyubiquitination GO:0000209 15 14 0,000 0,01416503 0,02713697 ! glycine metabolic process GO:0006544 15 14 0,000 0,01416503 0,02712242 ! plasma membrane organization GO:0007009 14 14 0,000 0,01416503 0,02710788 ! tyrosine metabolic process GO:0006570 16 14 0,000 0,01416503 0,02709336 ! response to retinoic acid GO:0032526 14 14 0,000 0,01416503 0,02707886 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 16 14 0,000 0,01416503 0,02706437 ! lysosomal transport GO:0007041 14 14 0,000 0,01416503 0,0270499 ! rough endoplasmic reticulum GO:0005791 14 14 0,000 0,01416503 0,02703544 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 14 14 0,000 0,01416503 0,027021 ! regulation of the force of heart contraction GO:0002026 15 14 0,000 0,01416503 0,02700657 ! bone mineralization GO:0030282 14 14 0,000 0,01416503 0,02699216 ! protein kinase activator activity GO:0030295 14 14 0,000 0,01416503 0,02697776 ! protein serine/threonine kinase inhibitor activity GO:0030291 14 14 0,000 0,01416503 0,02696338 ! NLS-bearing substrate import into nucleus GO:0006607 15 14 0,000 0,01416503 0,02694902 ! cerebellum development GO:0021549 15 14 0,000 0,01416503 0,02693467 ! G1 phase GO:0051318 14 14 0,000 0,01416503 0,02692033 ! negative regulation of blood coagulation GO:0030195 16 14 0,000 0,01416503 0,02690601 ! negative regulation of protein secretion GO:0050709 14 14 0,000 0,01416503 0,02689171 ! water homeostasis GO:0030104 14 14 0,000 0,01416503 0,02687742 ! peptide hormone binding GO:0017046 14 14 0,000 0,01416503 0,02686315 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,01416503 0,02684889 ! glutamine family amino acid biosynthetic process GO:0009084 15 14 0,000 0,01416503 0,02683464 ! regulation of ATPase activity GO:0043462 15 14 0,000 0,01416503 0,02682042 ! racemase and epimerase activity GO:0016854 14 14 0,000 0,01416503 0,0268062 ! regulation of leukocyte mediated cytotoxicity GO:0001910 18 14 0,000 0,01416503 0,026792 ! release of cytochrome c from mitochondria GO:0001836 14 14 0,000 0,01416503 0,02677782 ! positive regulation of calcium ion transport GO:0051928 17 14 0,000 0,01416503 0,02676365 ! regulation of blood vessel endothelial cell migration GO:0043535 14 14 0,000 0,01416503 0,0267495 ! regulation of calcium-mediated signaling GO:0050848 16 14 0,000 0,01416503 0,02673536 ! positive regulation of synaptic transmission GO:0050806 14 14 0,000 0,01416503 0,02672124 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 16 14 0,000 0,01416503 0,02670713 ! lactation GO:0007595 15 14 0,000 0,01416503 0,02669304 ! reproductive cellular process GO:0048610 14 14 0,000 0,01416503 0,02667896 ! positive regulation of cell killing GO:0031343 18 14 0,000 0,01416503 0,02666489 ! sulfur amino acid biosynthetic process GO:0000097 15 14 0,000 0,01416503 0,02665085 ! dicarboxylic acid transport GO:0006835 14 14 0,000 0,01416503 0,02663681 ! regulation of B cell proliferation GO:0030888 18 14 0,000 0,01416503 0,02662279 ! inorganic anion exchanger activity GO:0005452 15 14 0,000 0,01416503 0,02660879 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 15 14 0,000 0,01416503 0,0265948 ! negative regulation of cytokine biosynthetic process GO:0042036 14 14 0,000 0,01416503 0,02658082 ! negative regulation of ion transport GO:0043271 14 14 0,000 0,01416503 0,02656686 ! retinoic acid receptor binding GO:0042974 14 14 0,000 0,01416503 0,02655292 ! startle response GO:0001964 14 14 0,000 0,01416503 0,02653898 ! 2 iron, 2 sulfur cluster binding GO:0051537 14 14 0,000 0,01416503 0,02652507 ! activation of MAPKK activity GO:0000186 15 14 0,000 0,01416503 0,02651117 ! response to hexose stimulus GO:0009746 14 14 0,000 0,01416503 0,02649728 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! cytokine metabolic process GO:0042107 14 14 0,000 0,01416503 0,02648341 ! organic alcohol transport GO:0015850 15 14 0,000 0,01416503 0,02646955 ! preassembly of GPI anchor in ER membrane GO:0016254 15 14 0,000 0,01416503 0,0264557 ! calcium ion transmembrane transporter activity GO:0015085 16 14 0,000 0,01416503 0,02644187 ! eukaryotic translation initiation factor 4F complex GO:0016281 14 14 0,000 0,01416503 0,02642806 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,01416503 0,02641426 ! L-amino acid transport GO:0015807 14 14 0,000 0,01416503 0,02640047 ! microfilament motor activity GO:0000146 14 14 0,000 0,01416503 0,0263867 ! stem cell development GO:0048864 14 14 0,000 0,01416503 0,02637294 GO:0019827|stem cell maintenance, ! positive regulation of protein import into nucleus GO:0042307 15 14 0,000 0,01416503 0,0263592 ! DNA replication initiation GO:0006270 14 14 0,000 0,01416503 0,02634547 ! T cell differentiation in the thymus GO:0033077 18 14 0,000 0,01416503 0,02633176 ! regulation of cellular pH GO:0030641 14 14 0,000 0,01416503 0,02631806 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,01416503 0,02630437 ! calcium activated cation channel activity GO:0005227 16 14 0,000 0,01416503 0,0262907 ! sulfuric ester hydrolase activity GO:0008484 15 14 0,000 0,01416503 0,02627704 ! serotonin receptor activity GO:0004993 14 14 0,000 0,01416503 0,0262634 ! positive regulation of bone mineralization GO:0030501 15 14 0,000 0,01416503 0,02624977 ! synaptic transmission, cholinergic GO:0007271 15 14 0,000 0,01416503 0,02623615 ! dopamine metabolic process GO:0042417 17 14 0,000 0,01416503 0,02622255 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,01416503 0,02620897 ! ion gated channel activity GO:0022839 16 14 0,000 0,01416503 0,02619539 ! male genitalia development GO:0030539 14 14 0,000 0,01416503 0,02618183 ! regulation of axon extension GO:0030516 15 14 0,000 0,01416503 0,02616829 ! regulation of BMP signaling pathway GO:0030510 14 14 0,000 0,01416503 0,02615476 ! estrogen receptor signaling pathway GO:0030520 14 14 0,000 0,01416503 0,02614124 ! interleukin-1 receptor binding GO:0005149 14 14 0,000 0,01416503 0,02612774 ! defense response to virus GO:0051607 19 14 0,000 0,01416503 0,02611425 ! cadherin binding GO:0045296 16 14 0,000 0,01416503 0,02610078 ! negative regulation of hormone secretion GO:0046888 16 15 0,000 0,01516961 0,02793743 ! nuclear replication fork GO:0043596 16 15 0,000 0,01516961 0,02792303 ! skin development GO:0043588 16 15 0,000 0,01516961 0,02790865 ! phosphoinositide phosphorylation GO:0046854 16 15 0,000 0,01516961 0,02789428 GO:0046834|lipid phosphorylation, ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,01516961 0,02787992 ! cardiac muscle contraction GO:0060048 16 15 0,000 0,01516961 0,02786558 ! polysome GO:0005844 16 15 0,000 0,01516961 0,02785125 ! negative regulation of peptidase activity GO:0010466 16 15 0,000 0,01516961 0,02783694 ! mitotic chromosome condensation GO:0007076 15 15 0,000 0,01516961 0,02782264 ! regulation of viral genome replication GO:0045069 15 15 0,000 0,01516961 0,02780836 ! regulation of survival gene product expression GO:0045884 15 15 0,000 0,01516961 0,02779409 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 15 0,000 0,01516961 0,02777984 ! glycoprotein catabolic process GO:0006516 15 15 0,000 0,01516961 0,0277656 ! DNA duplex unwinding GO:0032508 15 15 0,000 0,01516961 0,02775138 GO:0032392|DNA geometric change, ! glutamine metabolic process GO:0006541 16 15 0,000 0,01516961 0,02773717 ! proton-transporting V-type ATPase complex GO:0033176 15 15 0,000 0,01516961 0,02772297 ! response to vitamin A GO:0033189 15 15 0,000 0,01516961 0,02770879 ! protease binding GO:0002020 16 15 0,000 0,01516961 0,02769462 ! regulation of ion transmembrane transporter activity GO:0032412 15 15 0,000 0,01516961 0,02768047 ! actin filament bundle formation GO:0051017 15 15 0,000 0,01516961 0,02766634 ! calcium ion-dependent exocytosis GO:0017156 15 15 0,000 0,01516961 0,02765221 ! purine nucleoside monophosphate metabolic process GO:0009126 16 15 0,000 0,01516961 0,02763811 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! protein export from nucleus GO:0006611 15 15 0,000 0,01516961 0,02762401 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,01516961 0,02760993 ! positive regulation of biomineral formation GO:0070169 16 15 0,000 0,01516961 0,02759587 ! positive regulation of oxidoreductase activity GO:0051353 15 15 0,000 0,01516961 0,02758182 ! filopodium GO:0030175 15 15 0,000 0,01516961 0,02756778 ! negative regulation of inflammatory response GO:0050728 15 15 0,000 0,01516961 0,02755376 ! positive regulation of transmission of nerve impulse GO:0051971 15 15 0,000 0,01516961 0,02753975 ! branched chain family amino acid metabolic process GO:0009081 15 15 0,000 0,01516961 0,02752575 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01516961 0,02751178 ! heme biosynthetic process GO:0006783 15 15 0,000 0,01516961 0,02749781 ! SMAD binding GO:0046332 16 15 0,000 0,01516961 0,02748386 ! nerve development GO:0021675 16 15 0,000 0,01516961 0,02746992 ! epithelial to mesenchymal transition GO:0001837 16 15 0,000 0,01516961 0,027456 ! mannose binding GO:0005537 15 15 0,000 0,01516961 0,02744209 ! phosphoprotein binding GO:0051219 17 15 0,000 0,01516961 0,0274282 ! mismatched DNA binding GO:0030983 15 15 0,000 0,01516961 0,02741431 ! antigen receptor-mediated signaling pathway GO:0050851 21 15 0,000 0,01516961 0,02740045 ! regulation of skeletal muscle tissue development GO:0048641 15 15 0,000 0,01516961 0,0273866 ! synaptonemal complex GO:0000795 15 15 0,000 0,01516961 0,02737276 ! N-terminal protein amino acid modification GO:0031365 16 15 0,000 0,01516961 0,02735893 ! positive regulation of protein complex assembly GO:0031334 15 15 0,000 0,01516961 0,02734512 ! water transport GO:0006833 15 15 0,000 0,01516961 0,02733132 GO:0042044|fluid transport, ! phosphatidylinositol metabolic process GO:0046488 16 15 0,000 0,01516961 0,02731754 ! viral genome replication GO:0019079 15 15 0,000 0,01516961 0,02730377 ! phosphatidylcholine metabolic process GO:0046470 17 15 0,000 0,01516961 0,02729002 ! inositol metabolic process GO:0006020 15 15 0,000 0,01516961 0,02727628 ! sulfate transport GO:0008272 15 15 0,000 0,01516961 0,02726255 ! protein-lipid complex GO:0032994 15 15 0,000 0,01516961 0,02724884 GO:0034358|plasma lipoprotein particle, ! positive regulation of ion transport GO:0043270 18 15 0,000 0,01516961 0,02723514 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 15 15 0,000 0,01516961 0,02722145 ! heart looping GO:0001947 15 15 0,000 0,01516961 0,02720778 ! isoprenoid biosynthetic process GO:0008299 16 15 0,000 0,01516961 0,02719412 ! protein histidine kinase activity GO:0004673 16 15 0,000 0,01516961 0,02718047 GO:0000155|two-component sensor activity, ! cardiac muscle tissue development GO:0048738 15 15 0,000 0,01516961 0,02716684 ! regulation of striated muscle contraction GO:0006942 16 15 0,000 0,01516961 0,02715323 ! response to osmotic stress GO:0006970 16 15 0,000 0,01516961 0,02713962 ! fructose metabolic process GO:0006000 15 15 0,000 0,01516961 0,02712603 ! ubiquitin binding GO:0043130 15 15 0,000 0,01516961 0,02711246 ! vesicle coating GO:0006901 16 15 0,000 0,01516961 0,02709889 ! DNA integration GO:0015074 16 15 0,000 0,01516961 0,02708534 ! alcohol binding GO:0043178 16 15 0,000 0,01516961 0,02707181 ! disulfide oxidoreductase activity GO:0015036 15 15 0,000 0,01516961 0,02705828 ! intermediate filament cytoskeleton organization GO:0045104 16 15 0,000 0,01516961 0,02704478 ! regulation of vasodilation GO:0042312 15 15 0,000 0,01516961 0,02703128 ! genitalia development GO:0048806 15 15 0,000 0,01516961 0,0270178 ! structural constituent of eye lens GO:0005212 15 15 0,000 0,01516961 0,02700433 ! regulation of monooxygenase activity GO:0032768 15 15 0,000 0,01516961 0,02699087 ! voltage-gated sodium channel activity GO:0005248 17 15 0,000 0,01516961 0,02697743 ! ribonucleoprotein binding GO:0043021 16 15 0,000 0,01516961 0,026964 ! proton-transporting ATP synthase complex GO:0045259 15 15 0,000 0,01516961 0,02695059 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 15 15 0,000 0,01516961 0,02693719 ! regulation of immunoglobulin production GO:0002637 19 15 0,000 0,01516961 0,0269238 ! retinoic acid receptor activity GO:0003708 15 15 0,000 0,01516961 0,02691043 ! receptor activator activity GO:0030546 15 15 0,000 0,01516961 0,02689706 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 15 15 0,000 0,01516961 0,02688372 ! protein transmembrane transporter activity GO:0008320 15 15 0,000 0,01516961 0,02687038 ! histone binding GO:0042393 15 15 0,000 0,01516961 0,02685706 ! phosphoinositide 3-kinase activity GO:0035004 16 15 0,000 0,01516961 0,02684375 ! sialyltransferase activity GO:0008373 15 15 0,000 0,01516961 0,02683045 ! platelet-derived growth factor receptor binding GO:0005161 16 15 0,000 0,01516961 0,02681717 ! drug transporter activity GO:0015238 15 15 0,000 0,01516961 0,0268039 ! negative regulation of homeostatic process GO:0032845 15 15 0,000 0,01516961 0,02679065 ! phosphoinositide 3-kinase complex GO:0005942 16 15 0,000 0,01516961 0,0267774 ! binding of sperm to zona pellucida GO:0007339 16 15 0,000 0,01516961 0,02676417 ! peptide hormone processing GO:0016486 17 15 0,000 0,01516961 0,02675096 ! aldo-keto reductase activity GO:0004033 15 15 0,000 0,01516961 0,02673775 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,01516961 0,02672456 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 16 16 0,000 0,01617324 0,02847863 ! positive regulation of cell size GO:0045793 16 16 0,000 0,01617324 0,02846459 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,01617324 0,02845057 ! positive regulation of hormone secretion GO:0046887 17 16 0,000 0,01617324 0,02843656 ! protein amino acid ADP-ribosylation GO:0006471 18 16 0,000 0,01617324 0,02842257 ! response to vitamin GO:0033273 16 16 0,000 0,01617324 0,02840859 ! gene silencing by RNA GO:0031047 16 16 0,000 0,01617324 0,02839462 ! regulation of postsynaptic membrane potential GO:0060078 18 16 0,000 0,01617324 0,02838067 ! kinesin complex GO:0005871 16 16 0,000 0,01617324 0,02836673 ! cornified envelope GO:0001533 18 16 0,000 0,01617324 0,0283528 ! regulation of transmembrane transporter activity GO:0022898 16 16 0,000 0,01617324 0,02833889 GO:0032409|regulation of transporter activity, ! negative regulation of epithelial cell proliferation GO:0050680 17 16 0,000 0,01617324 0,02832499 ! pyrimidine ribonucleotide metabolic process GO:0009218 18 16 0,000 0,01617324 0,02831111 ! pituitary gland development GO:0021983 16 16 0,000 0,01617324 0,02829723 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 18 16 0,000 0,01617324 0,02828338 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 19 16 0,000 0,01617324 0,02826953 ! cell-substrate junction assembly GO:0007044 18 16 0,000 0,01617324 0,0282557 ! peptidyl-serine phosphorylation GO:0018105 16 16 0,000 0,01617324 0,02824188 ! branching involved in ureteric bud morphogenesis GO:0001658 16 16 0,000 0,01617324 0,02822808 GO:0060675|ureteric bud morphogenesis, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 16 16 0,000 0,01617324 0,02821429 ! nucleobase metabolic process GO:0009112 19 16 0,000 0,01617324 0,02820052 ! beta-catenin binding GO:0008013 17 16 0,000 0,01617324 0,02818675 ! regulation of steroid metabolic process GO:0019218 17 16 0,000 0,01617324 0,028173 ! neuron recognition GO:0008038 17 16 0,000 0,01617324 0,02815927 ! oogenesis GO:0048477 19 16 0,000 0,01617324 0,02814554 ! low-density lipoprotein binding GO:0030169 17 16 0,000 0,01617324 0,02813183 ! clathrin vesicle coat GO:0030125 19 16 0,000 0,01617324 0,02811814 ! COPI-coated vesicle GO:0030137 16 16 0,000 0,01617324 0,02810445 ! sphingolipid biosynthetic process GO:0030148 16 16 0,000 0,01617324 0,02809079 ! biomineral formation GO:0031214 16 16 0,000 0,01617324 0,02807713 ! vitamin transport GO:0051180 16 16 0,000 0,01617324 0,02806349 ! folic acid and derivative metabolic process GO:0006760 16 16 0,000 0,01617324 0,02804986 ! organic cation transport GO:0015695 16 16 0,000 0,01617324 0,02803624 ! proximal/distal pattern formation GO:0009954 16 16 0,000 0,01617324 0,02802264 ! regulation of glucose import GO:0046324 17 16 0,000 0,01617324 0,02800905 GO:0010827|regulation of glucose transport, ! aromatic compound biosynthetic process GO:0019438 17 16 0,000 0,01617324 0,02799547 ! aromatic compound catabolic process GO:0019439 18 16 0,000 0,01617324 0,02798191 ! negative regulation of coagulation GO:0050819 18 16 0,000 0,01617324 0,02796836 ! tRNA binding GO:0000049 16 16 0,000 0,01617324 0,02795482 ! regulation of cell killing GO:0031341 20 16 0,000 0,01617324 0,02794129 ! negative regulation of defense response GO:0031348 16 16 0,000 0,01617324 0,02792778 ! regulation of neuronal synaptic plasticity GO:0048168 16 16 0,000 0,01617324 0,02791428 ! hindlimb morphogenesis GO:0035137 16 16 0,000 0,01617324 0,0279008 ! bile acid metabolic process GO:0008206 16 16 0,000 0,01617324 0,02788733 ! axis specification GO:0009798 16 16 0,000 0,01617324 0,02787387 ! adult walking behavior GO:0007628 17 16 0,000 0,01617324 0,02786042 ! C-C chemokine binding GO:0019957 16 16 0,000 0,01617324 0,02784699 GO:0016493|C-C chemokine receptor activity, ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 18 16 0,000 0,01617324 0,02783357 ! protein phosphatase binding GO:0019903 17 16 0,000 0,01617324 0,02782016 ! epidermis morphogenesis GO:0048730 16 16 0,000 0,01617324 0,02780677 ! acyl-CoA dehydrogenase activity GO:0003995 16 16 0,000 0,01617324 0,02779339 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01617324 0,02778002 ! SH2 domain binding GO:0042169 19 16 0,000 0,01617324 0,02776666 ! UDP-galactosyltransferase activity GO:0035250 17 16 0,000 0,01617324 0,02775332 ! RNA methyltransferase activity GO:0008173 16 16 0,000 0,01617324 0,02773999 ! neutral amino acid transport GO:0015804 16 16 0,000 0,01617324 0,02772667 ! glucuronosyltransferase activity GO:0015020 17 16 0,000 0,01617324 0,02771337 ! regulation of alpha-beta T cell differentiation GO:0046637 16 16 0,000 0,01617324 0,02770007 ! cellular pigmentation GO:0033059 16 16 0,000 0,01617324 0,0276868 ! mannosidase activity GO:0015923 19 16 0,000 0,01617324 0,02767353 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 16 16 0,000 0,01617324 0,02766028 ! negative regulation of tissue remodeling GO:0034104 16 16 0,000 0,01617324 0,02764703 ! positive regulation of neurological system process GO:0031646 16 16 0,000 0,01617324 0,02763381 ! neuromuscular synaptic transmission GO:0007274 16 16 0,000 0,01617324 0,02762059 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,01617324 0,02760739 ! sperm-egg recognition GO:0035036 17 16 0,000 0,01617324 0,0275942 ! axoneme GO:0005930 16 16 0,000 0,01617324 0,02758102 ! anion exchanger activity GO:0015380 18 17 0,000 0,01717592 0,02927695 ! neuron maturation GO:0042551 18 17 0,000 0,01717592 0,02926298 ! metencephalon development GO:0022037 18 17 0,000 0,01717592 0,02924903 ! regulation of lipid biosynthetic process GO:0046890 18 17 0,000 0,01717592 0,02923509 ! reciprocal meiotic recombination GO:0007131 17 17 0,000 0,01717592 0,02922116 ! hemoglobin complex GO:0005833 18 17 0,000 0,01717592 0,02920725 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 17 17 0,000 0,01717592 0,02919334 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 17 17 0,000 0,01717592 0,02917946 ! protein amino acid deacetylation GO:0006476 17 17 0,000 0,01717592 0,02916558 ! protein amino acid acetylation GO:0006473 19 17 0,000 0,01717592 0,02915172 ! positive regulation of nucleocytoplasmic transport GO:0046824 18 17 0,000 0,01717592 0,02913787 ! regulation of neurotransmitter secretion GO:0046928 18 17 0,000 0,01717592 0,02912403 ! striated muscle thick filament GO:0005863 19 17 0,000 0,01717592 0,02911021 GO:0032982|myosin filament, ! gamma-aminobutyric acid signaling pathway GO:0007214 17 17 0,000 0,01717592 0,0290964 ! glial cell development GO:0021782 17 17 0,000 0,01717592 0,02908261 ! regulation of muscle cell differentiation GO:0051147 17 17 0,000 0,01717592 0,02906882 ! pancreas development GO:0031016 17 17 0,000 0,01717592 0,02905505 ! acetylcholine receptor activity GO:0015464 17 17 0,000 0,01717592 0,02904129 ! nuclear heterochromatin GO:0005720 18 17 0,000 0,01717592 0,02902755 ! calcium-dependent protein binding GO:0048306 19 17 0,000 0,01717592 0,02901382 ! cerebral cortex development GO:0021987 17 17 0,000 0,01717592 0,0290001 ! cellular response to starvation GO:0009267 18 17 0,000 0,01717592 0,0289864 ! signal sequence binding GO:0005048 17 17 0,000 0,01717592 0,0289727 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 17 17 0,000 0,01717592 0,02895902 ! cellular macromolecular complex disassembly GO:0034623 18 17 0,000 0,01717592 0,02894536 ! transforming growth factor beta receptor activity GO:0005024 17 17 0,000 0,01717592 0,02893171 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,01717592 0,02891806 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 17 17 0,000 0,01717592 0,02890444 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 17 0,000 0,01717592 0,02889082 ! actin filament bundle GO:0032432 17 17 0,000 0,01717592 0,02887722 GO:0001725|stress fiber, ! small nucleolar ribonucleoprotein complex GO:0005732 17 17 0,000 0,01717592 0,02886363 ! response to lipopolysaccharide GO:0032496 17 17 0,000 0,01717592 0,02885005 ! plasma membrane fusion GO:0045026 18 17 0,000 0,01717592 0,02883649 ! regulation of protein binding GO:0043393 18 17 0,000 0,01717592 0,02882294 ! recycling endosome GO:0055037 18 17 0,000 0,01717592 0,0288094 ! prostaglandin metabolic process GO:0006693 18 17 0,000 0,01717592 0,02879588 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 19 17 0,000 0,01717592 0,02878236 ! regulation of Rho GTPase activity GO:0032319 17 17 0,000 0,01717592 0,02876886 ! regulation of immunoglobulin mediated immune response GO:0002889 21 17 0,000 0,01717592 0,02875537 GO:0002712|regulation of B cell mediated immunity, ! receptor signaling complex scaffold activity GO:0030159 17 17 0,000 0,01717592 0,0287419 ! positive regulation of cytokine secretion GO:0050715 17 17 0,000 0,01717592 0,02872844 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 17 0,000 0,01717592 0,02871499 ! endodeoxyribonuclease activity GO:0004520 17 17 0,000 0,01717592 0,02870155 ! sphingolipid catabolic process GO:0030149 18 17 0,000 0,01717592 0,02868813 ! steroid catabolic process GO:0006706 17 17 0,000 0,01717592 0,02867471 ! oxygen transport GO:0015671 18 17 0,000 0,01717592 0,02866132 GO:0005344|oxygen transporter activity, ! phosphatidylinositol binding GO:0005545 19 17 0,000 0,01717592 0,02864793 ! hyaluronic acid binding GO:0005540 17 17 0,000 0,01717592 0,02863455 ! negative regulation of T cell activation GO:0050868 17 17 0,000 0,01717592 0,02862119 ! regulation of glucose metabolic process GO:0010906 17 17 0,000 0,01717592 0,02860784 ! G2/M transition of mitotic cell cycle GO:0000086 17 17 0,000 0,01717592 0,02859451 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 17 17 0,000 0,01717592 0,02858118 ! glycosaminoglycan biosynthetic process GO:0006024 17 17 0,000 0,01717592 0,02856787 ! MAP kinase kinase kinase activity GO:0004709 18 17 0,000 0,01717592 0,02855457 ! L-ascorbic acid binding GO:0031418 17 17 0,000 0,01717592 0,02854128 ! negative regulation of endothelial cell proliferation GO:0001937 17 17 0,000 0,01717592 0,02852801 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 18 17 0,000 0,01717592 0,02851474 ! photoreceptor cell maintenance GO:0045494 17 17 0,000 0,01717592 0,02850149 ! response to carbohydrate stimulus GO:0009743 17 17 0,000 0,01717592 0,02848826 ! calmodulin-dependent protein kinase activity GO:0004683 19 17 0,000 0,01717592 0,02847503 ! fucose metabolic process GO:0006004 19 17 0,000 0,01717592 0,02846182 ! D-ribose metabolic process GO:0006014 18 17 0,000 0,01717592 0,02844862 ! membrane budding GO:0006900 18 17 0,000 0,01717592 0,02843543 ! AMP binding GO:0016208 17 17 0,000 0,01717592 0,02842225 ! nuclear ubiquitin ligase complex GO:0000152 17 17 0,000 0,01717592 0,02840909 ! body fluid secretion GO:0007589 18 17 0,000 0,01717592 0,02839593 ! response to fungus GO:0009620 17 17 0,000 0,01717592 0,02838279 ! positive regulation of alpha-beta T cell activation GO:0046635 21 17 0,000 0,01717592 0,02836966 ! intermediate filament-based process GO:0045103 18 17 0,000 0,01717592 0,02835655 ! rRNA binding GO:0019843 17 17 0,000 0,01717592 0,02834344 ! nucleotide-excision repair, DNA gap filling GO:0006297 18 17 0,000 0,01717592 0,02833035 ! regulation of interleukin-2 production GO:0032663 17 17 0,000 0,01717592 0,02831727 ! voltage-gated chloride channel activity GO:0005247 17 17 0,000 0,01717592 0,02830421 ! neutrophil chemotaxis GO:0030593 18 17 0,000 0,01717592 0,02829115 ! long-chain fatty acid transport GO:0015909 17 17 0,000 0,01717592 0,02827811 ! tissue regeneration GO:0042246 17 17 0,000 0,01717592 0,02826508 ! detection of biotic stimulus GO:0009595 18 17 0,000 0,01717592 0,02825206 ! muscle maintenance GO:0046716 18 17 0,000 0,01717592 0,02823905 ! cell-cell junction organization GO:0045216 17 17 0,000 0,01717592 0,02822605 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 17 17 0,000 0,01717592 0,02821307 ! somatic recombination of immunoglobulin gene segments GO:0016447 17 17 0,000 0,01717592 0,0282001 ! cell-cell adherens junction GO:0005913 17 17 0,000 0,01717592 0,02818714 ! triacylglycerol lipase activity GO:0004806 17 17 0,000 0,01717592 0,02817419 ! ATP-dependent DNA helicase activity GO:0004003 17 17 0,000 0,01717592 0,02816126 ! chaperone binding GO:0051087 18 18 0,000 0,01817764 0,02978998 ! positive regulation of ossification GO:0045778 19 18 0,000 0,01817764 0,02977632 ! pteridine and derivative metabolic process GO:0042558 19 18 0,000 0,01817764 0,02976266 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,01817764 0,02974902 GO:0005763|mitochondrial small ribosomal subunit, ! signal complex assembly GO:0007172 18 18 0,000 0,01817764 0,0297354 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 19 18 0,000 0,01817764 0,02972178 ! limbic system development GO:0021761 18 18 0,000 0,01817764 0,02970818 ! cellular response to hydrogen peroxide GO:0070301 18 18 0,000 0,01817764 0,02969459 GO:0042744|hydrogen peroxide catabolic process, ! MHC class II protein complex GO:0042613 18 18 0,000 0,01817764 0,02968101 ! positive regulation of proteolysis GO:0045862 19 18 0,000 0,01817764 0,02966744 ! deoxyribonucleotide metabolic process GO:0009262 19 18 0,000 0,01817764 0,02965389 ! lysosome organization GO:0007040 18 18 0,000 0,01817764 0,02964035 ! central nervous system neuron development GO:0021954 19 18 0,000 0,01817764 0,02962682 ! fatty acid beta-oxidation GO:0006635 18 18 0,000 0,01817764 0,02961331 ! regulation of viral reproduction GO:0050792 18 18 0,000 0,01817764 0,0295998 ! peptide cross-linking GO:0018149 20 18 0,000 0,01817764 0,02958631 ! ventricular cardiac muscle morphogenesis GO:0055010 19 18 0,000 0,01817764 0,02957283 ! presynaptic membrane GO:0042734 19 18 0,000 0,01817764 0,02955937 ! embryonic digit morphogenesis GO:0042733 20 18 0,000 0,01817764 0,02954591 ! neural crest cell migration GO:0001755 18 18 0,000 0,01817764 0,02953247 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,01817764 0,02951904 ! positive regulation of adaptive immune response GO:0002821 22 18 0,000 0,01817764 0,02950562 ! positive regulation of intracellular transport GO:0032388 19 18 0,000 0,01817764 0,02949222 ! negative regulation of intracellular transport GO:0032387 18 18 0,000 0,01817764 0,02947882 ! peptidyl-serine modification GO:0018209 18 18 0,000 0,01817764 0,02946544 ! cell-cell recognition GO:0009988 19 18 0,000 0,01817764 0,02945207 ! vitamin D receptor binding GO:0042809 19 18 0,000 0,01817764 0,02943872 ! porphyrin biosynthetic process GO:0006779 18 18 0,000 0,01817764 0,02942537 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 18 0,000 0,01817764 0,02941204 ! actin filament-based movement GO:0030048 18 18 0,000 0,01817764 0,02939872 ! negative regulation of translation GO:0017148 20 18 0,000 0,01817764 0,02938541 ! Rab GTPase binding GO:0017137 18 18 0,000 0,01817764 0,02937211 ! histone deacetylase activity GO:0004407 19 18 0,000 0,01817764 0,02935883 GO:0033558|protein deacetylase activity, ! protein import into nucleus, docking GO:0000059 18 18 0,000 0,01817764 0,02934556 ! negative regulation of cell cycle process GO:0010948 18 18 0,000 0,01817764 0,02933229 ! glycerol metabolic process GO:0006071 19 18 0,000 0,01817764 0,02931905 ! post-Golgi vesicle-mediated transport GO:0006892 18 18 0,000 0,01817764 0,02930581 ! intra-Golgi vesicle-mediated transport GO:0006891 18 18 0,000 0,01817764 0,02929259 ! aminoglycan catabolic process GO:0006026 18 18 0,000 0,01817764 0,02927937 ! aminoglycan biosynthetic process GO:0006023 18 18 0,000 0,01817764 0,02926617 ! small conjugating protein binding GO:0032182 18 18 0,000 0,01817764 0,02925298 ! memory GO:0007613 19 18 0,000 0,01817764 0,02923981 ! C21-steroid hormone metabolic process GO:0008207 18 18 0,000 0,01817764 0,02922664 ! regulation of DNA recombination GO:0000018 22 18 0,000 0,01817764 0,02921349 ! inactivation of MAPK activity GO:0000188 19 18 0,000 0,01817764 0,02920035 ! pigmentation during development GO:0048066 21 18 0,000 0,01817764 0,02918722 ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 18 0,000 0,01817764 0,0291741 ! acetylcholine binding GO:0042166 19 18 0,000 0,01817764 0,02916099 ! neurotransmitter:sodium symporter activity GO:0005328 18 18 0,000 0,01817764 0,0291479 ! neurotransmitter metabolic process GO:0042133 23 18 0,000 0,01817764 0,02913482 ! neuromuscular junction development GO:0007528 21 18 0,000 0,01817764 0,02912174 ! nonmotile primary cilium GO:0031513 19 18 0,000 0,01817764 0,02910869 ! coreceptor activity GO:0015026 18 18 0,000 0,01817764 0,02909564 ! behavioral interaction between organisms GO:0051705 18 18 0,000 0,01817764 0,0290826 ! carbonate dehydratase activity GO:0004089 19 18 0,000 0,01817764 0,02906958 ! cytolysis GO:0019835 18 18 0,000 0,01817764 0,02905657 ! phosphate binding GO:0042301 19 18 0,000 0,01817764 0,02904357 ! transport vesicle membrane GO:0030658 21 18 0,000 0,01817764 0,02903058 ! specific transcriptional repressor activity GO:0016566 18 18 0,000 0,01817764 0,0290176 ! DNA modification GO:0006304 20 18 0,000 0,01817764 0,02900463 ! bicarbonate transmembrane transporter activity GO:0015106 19 18 0,000 0,01817764 0,02899168 ! detection of chemical stimulus GO:0009593 19 18 0,000 0,01817764 0,02897874 ! ionotropic glutamate receptor activity GO:0004970 20 18 0,000 0,01817764 0,0289658 ! aspartic-type endopeptidase activity GO:0004190 19 18 0,000 0,01817764 0,02895289 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 18 18 0,000 0,01817764 0,02893998 ! 3'-5' exonuclease activity GO:0008408 18 18 0,000 0,01817764 0,02892708 ! RNA polymerase II transcription mediator activity GO:0016455 19 18 0,000 0,01817764 0,0289142 ! water-soluble vitamin biosynthetic process GO:0042364 19 18 0,000 0,01817764 0,02890132 ! connexon complex GO:0005922 18 18 0,000 0,01817764 0,02888846 ! solute:hydrogen antiporter activity GO:0015299 18 18 0,000 0,01817764 0,02887561 ! mRNA export from nucleus GO:0006406 21 19 0,000 0,01917841 0,03045181 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 20 19 0,000 0,01917841 0,03043828 ! regulation of interferon-gamma production GO:0032649 20 19 0,000 0,01917841 0,03042475 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 20 19 0,000 0,01917841 0,03041124 ! anion:anion antiporter activity GO:0015301 20 19 0,000 0,01917841 0,03039774 ! cAMP metabolic process GO:0046058 19 19 0,000 0,01917841 0,03038426 ! spindle microtubule GO:0005876 20 19 0,000 0,01917841 0,03037078 ! ovarian follicle development GO:0001541 19 19 0,000 0,01917841 0,03035732 ! retinoid metabolic process GO:0001523 19 19 0,000 0,01917841 0,03034387 GO:0016101|diterpenoid metabolic process, ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 21 19 0,000 0,01917841 0,03033043 ! vacuolar transport GO:0007034 19 19 0,000 0,01917841 0,03031701 ! cellular response to unfolded protein GO:0034620 21 19 0,000 0,01917841 0,03030359 GO:0030968|endoplasmic reticulum unfolded protein response, ! threonine-type endopeptidase activity GO:0004298 19 19 0,000 0,01917841 0,03029019 GO:0070003|threonine-type peptidase activity, ! myofibril assembly GO:0030239 19 19 0,000 0,01917841 0,0302768 GO:0055002|striated muscle cell development, ! monocarboxylic acid transmembrane transporter activity GO:0008028 20 19 0,000 0,01917841 0,03026342 ! positive regulation of multicellular organism growth GO:0040018 19 19 0,000 0,01917841 0,03025005 ! cell projection membrane GO:0031253 20 19 0,000 0,01917841 0,0302367 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,01917841 0,03022335 ! transcriptional repressor complex GO:0017053 19 19 0,000 0,01917841 0,03021002 ! vitamin A metabolic process GO:0006776 19 19 0,000 0,01917841 0,0301967 ! positive regulation of myeloid cell differentiation GO:0045639 20 19 0,000 0,01917841 0,03018339 ! negative regulation of myeloid cell differentiation GO:0045638 19 19 0,000 0,01917841 0,0301701 ! glutamine family amino acid catabolic process GO:0009065 21 19 0,000 0,01917841 0,03015681 ! leukotriene biosynthetic process GO:0019370 19 19 0,000 0,01917841 0,03014354 GO:0043450|alkene biosynthetic process, ! gas transport GO:0015669 20 19 0,000 0,01917841 0,03013028 ! retinoid binding GO:0005501 19 19 0,000 0,01917841 0,03011703 GO:0019840|isoprenoid binding, ! peptide hormone secretion GO:0030072 20 19 0,000 0,01917841 0,03010379 ! protein stabilization GO:0050821 20 19 0,000 0,01917841 0,03009056 ! cellular monovalent inorganic cation homeostasis GO:0030004 20 19 0,000 0,01917841 0,03007735 ! myeloid leukocyte differentiation GO:0002573 21 19 0,000 0,01917841 0,03006414 ! microtubule-based transport GO:0010970 19 19 0,000 0,01917841 0,03005095 ! protein complex scaffold GO:0032947 19 19 0,000 0,01917841 0,03003777 ! SNAP receptor activity GO:0005484 21 19 0,000 0,01917841 0,0300246 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,01917841 0,03001145 GO:0006479|protein amino acid methylation, ! regulation of systemic arterial blood pressure by hormone GO:0001990 19 19 0,000 0,01917841 0,0299983 GO:0050886|endocrine process, ! visual behavior GO:0007632 22 19 0,000 0,01917841 0,02998517 GO:0008542|visual learning, ! 4 iron, 4 sulfur cluster binding GO:0051539 21 19 0,000 0,01917841 0,02997204 ! glycoprotein binding GO:0001948 23 19 0,000 0,01917841 0,02995893 ! sensory perception of taste GO:0050909 19 19 0,000 0,01917841 0,02994583 ! myoblast differentiation GO:0045445 19 19 0,000 0,01917841 0,02993274 ! cell differentiation in spinal cord GO:0021515 19 19 0,000 0,01917841 0,02991967 ! immune response-activating cell surface receptor signaling pathway GO:0002429 25 19 0,000 0,01917841 0,0299066 ! myosin binding GO:0017022 19 19 0,000 0,01917841 0,02989355 ! organic acid:sodium symporter activity GO:0005343 19 19 0,000 0,01917841 0,02988051 ! cell aging GO:0007569 19 19 0,000 0,01917841 0,02986747 ! stem cell differentiation GO:0048863 19 19 0,000 0,01917841 0,02985445 ! regulation of myeloid leukocyte differentiation GO:0002761 21 19 0,000 0,01917841 0,02984145 ! heart process GO:0003015 20 19 0,000 0,01917841 0,02982845 GO:0060047|heart contraction, ! mismatch repair GO:0006298 19 19 0,000 0,01917841 0,02981546 ! secretory granule membrane GO:0030667 20 19 0,000 0,01917841 0,02980249 ! MHC protein binding GO:0042287 19 19 0,000 0,01917841 0,02978953 ! extracellular-glutamate-gated ion channel activity GO:0005234 21 19 0,000 0,01917841 0,02977657 ! chloride transmembrane transporter activity GO:0015108 20 19 0,000 0,01917841 0,02976363 ! GABA-A receptor activity GO:0004890 20 19 0,000 0,01917841 0,0297507 ! response to cytokine stimulus GO:0034097 20 19 0,000 0,01917841 0,02973779 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,01917841 0,02972488 ! translation elongation factor activity GO:0003746 22 19 0,000 0,01917841 0,02971198 ! insulin receptor binding GO:0005158 20 19 0,000 0,01917841 0,0296991 ! phosphoprotein phosphatase inhibitor activity GO:0004864 21 19 0,000 0,01917841 0,02968622 ! protein secretion GO:0009306 20 20 0,000 0,02017823 0,03122031 ! positive regulation of angiogenesis GO:0045766 22 20 0,000 0,02017823 0,03120679 ! proteasome core complex GO:0005839 20 20 0,000 0,02017823 0,03119328 ! positive regulation of bone remodeling GO:0046852 21 20 0,000 0,02017823 0,03117978 ! heterophilic cell adhesion GO:0007157 21 20 0,000 0,02017823 0,03116629 ! glutathione transferase activity GO:0004364 20 20 0,000 0,02017823 0,03115282 ! microtubule organizing center organization GO:0031023 20 20 0,000 0,02017823 0,03113936 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 20 20 0,000 0,02017823 0,0311259 ! actomyosin GO:0042641 20 20 0,000 0,02017823 0,03111247 ! positive regulation of innate immune response GO:0045089 20 20 0,000 0,02017823 0,03109904 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 20 0,000 0,02017823 0,03108562 ! vacuole organization GO:0007033 20 20 0,000 0,02017823 0,03107222 ! oxidoreductase activity, acting on heme group of donors GO:0016675 21 20 0,000 0,02017823 0,03105882 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! purine ribonucleoside metabolic process GO:0046128 23 20 0,000 0,02017823 0,03104544 GO:0042278|purine nucleoside metabolic process, ! chromosome condensation GO:0030261 20 20 0,000 0,02017823 0,03103207 ! regulation of exocytosis GO:0017157 21 20 0,000 0,02017823 0,03101871 ! vitamin biosynthetic process GO:0009110 21 20 0,000 0,02017823 0,03100537 ! glycosphingolipid metabolic process GO:0006687 20 20 0,000 0,02017823 0,03099203 ! kinase activator activity GO:0019209 20 20 0,000 0,02017823 0,03097871 ! diencephalon development GO:0021536 20 20 0,000 0,02017823 0,03096539 ! nuclear inner membrane GO:0005637 20 20 0,000 0,02017823 0,03095209 ! positive regulation of locomotion GO:0040017 20 20 0,000 0,02017823 0,0309388 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! synaptic vesicle transport GO:0048489 21 20 0,000 0,02017823 0,03092552 ! proteoglycan biosynthetic process GO:0030166 20 20 0,000 0,02017823 0,03091226 ! negative regulation of Wnt receptor signaling pathway GO:0030178 21 20 0,000 0,02017823 0,030899 ! leukocyte homeostasis GO:0001776 22 20 0,000 0,02017823 0,03088576 ! regulation of blood coagulation GO:0030193 22 20 0,000 0,02017823 0,03087252 ! positive regulation of osteoblast differentiation GO:0045669 22 20 0,000 0,02017823 0,0308593 ! regulation of generation of precursor metabolites and energy GO:0043467 21 20 0,000 0,02017823 0,03084609 ! ligase activity, forming carbon-sulfur bonds GO:0016877 20 20 0,000 0,02017823 0,03083289 ! phosphorus-oxygen lyase activity GO:0016849 20 20 0,000 0,02017823 0,0308197 ! embryonic organ morphogenesis GO:0048562 22 20 0,000 0,02017823 0,03080653 ! alditol metabolic process GO:0019400 21 20 0,000 0,02017823 0,03079336 ! liver development GO:0001889 20 20 0,000 0,02017823 0,03078021 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 20 0,000 0,02017823 0,03076707 ! chromosome, telomeric region GO:0000781 21 20 0,000 0,02017823 0,03075393 ! calcium-independent cell-cell adhesion GO:0016338 20 20 0,000 0,02017823 0,03074081 ! response to alkaloid GO:0043279 22 20 0,000 0,02017823 0,03072771 ! regulation of cell-matrix adhesion GO:0001952 22 20 0,000 0,02017823 0,03071461 GO:0010810|regulation of cell-substrate adhesion, ! transmembrane receptor protein phosphatase activity GO:0019198 27 20 0,000 0,02017823 0,03070152 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! smooth muscle contraction GO:0006939 21 20 0,000 0,02017823 0,03068845 ! heme metabolic process GO:0042168 22 20 0,000 0,02017823 0,03067538 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 20 20 0,000 0,02017823 0,03066233 ! sex determination GO:0007530 20 20 0,000 0,02017823 0,03064929 ! negative regulation of protein catabolic process GO:0042177 21 20 0,000 0,02017823 0,03063625 ! peptide secretion GO:0002790 21 20 0,000 0,02017823 0,03062323 ! regulation of alpha-beta T cell activation GO:0046634 24 20 0,000 0,02017823 0,03061022 ! interaction with host GO:0051701 24 20 0,000 0,02017823 0,03059723 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 26 20 0,000 0,02017823 0,03058424 ! vasodilation GO:0042311 21 20 0,000 0,02017823 0,03057126 ! regulation of tumor necrosis factor production GO:0032680 20 20 0,000 0,02017823 0,0305583 ! regulation of chromosome organization GO:0033044 20 20 0,000 0,02017823 0,03054535 ! inward rectifier potassium channel activity GO:0005242 20 20 0,000 0,02017823 0,0305324 ! activation of JUN kinase activity GO:0007257 20 20 0,000 0,02017823 0,03051947 ! cyclic nucleotide binding GO:0030551 22 20 0,000 0,02017823 0,03050655 ! somatic diversification of immunoglobulins GO:0016445 20 20 0,000 0,02017823 0,03049364 ! microvillus GO:0005902 20 20 0,000 0,02017823 0,03048074 ! tumor necrosis factor receptor binding GO:0005164 20 20 0,000 0,02017823 0,03046785 ! ATP-dependent RNA helicase activity GO:0004004 20 20 0,000 0,02017823 0,03045497 ! positive regulation of protein catabolic process GO:0045732 22 21 0,000 0,0211771 0,03194906 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 22 21 0,000 0,0211771 0,03193557 ! growth cone GO:0030426 22 21 0,000 0,0211771 0,03192209 ! oligosaccharide metabolic process GO:0009311 23 21 0,000 0,0211771 0,03190862 ! regulation of anti-apoptosis GO:0045767 21 21 0,000 0,0211771 0,03189516 ! hormone secretion GO:0046879 22 21 0,000 0,0211771 0,03188171 ! protein amino acid O-linked glycosylation GO:0006493 22 21 0,000 0,0211771 0,03186828 ! transition metal ion transmembrane transporter activity GO:0046915 21 21 0,000 0,0211771 0,03185485 ! voltage-gated calcium channel complex GO:0005891 24 21 0,000 0,0211771 0,03184144 GO:0034704|calcium channel complex, ! dicarboxylic acid metabolic process GO:0043648 22 21 0,000 0,0211771 0,03182804 ! apoptotic mitochondrial changes GO:0008637 21 21 0,000 0,0211771 0,03181465 ! protein phosphatase type 2A regulator activity GO:0008601 23 21 0,000 0,0211771 0,03180127 ! histone-lysine N-methyltransferase activity GO:0018024 23 21 0,000 0,0211771 0,0317879 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! activation of pro-apoptotic gene products GO:0008633 22 21 0,000 0,0211771 0,03177455 ! mitochondrial membrane organization GO:0007006 22 21 0,000 0,0211771 0,0317612 ! central nervous system neuron differentiation GO:0021953 22 21 0,000 0,0211771 0,03174787 ! Golgi stack GO:0005795 25 21 0,000 0,0211771 0,03173455 ! regulation of endothelial cell migration GO:0010594 21 21 0,000 0,0211771 0,03172123 ! muscle cell development GO:0055001 21 21 0,000 0,0211771 0,03170793 ! cholesterol biosynthetic process GO:0006695 22 21 0,000 0,0211771 0,03169465 ! regulation of vasoconstriction GO:0019229 22 21 0,000 0,0211771 0,03168137 ! deacetylase activity GO:0019213 22 21 0,000 0,0211771 0,0316681 ! phosphatase inhibitor activity GO:0019212 23 21 0,000 0,0211771 0,03165484 ! regulation of fatty acid metabolic process GO:0019217 22 21 0,000 0,0211771 0,0316416 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,0211771 0,03162837 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! sensory perception of pain GO:0019233 21 21 0,000 0,0211771 0,03161514 ! pentose metabolic process GO:0019321 22 21 0,000 0,0211771 0,03160193 ! collagen fibril organization GO:0030199 22 21 0,000 0,0211771 0,03158873 ! platelet activation GO:0030168 23 21 0,000 0,0211771 0,03157554 ! response to glucocorticoid stimulus GO:0051384 22 21 0,000 0,0211771 0,03156236 ! trans-Golgi network transport vesicle GO:0030140 24 21 0,000 0,0211771 0,0315492 ! glutathione metabolic process GO:0006749 21 21 0,000 0,0211771 0,03153604 ! DNA-directed RNA polymerase complex GO:0000428 22 21 0,000 0,0211771 0,03152289 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! terpenoid metabolic process GO:0006721 21 21 0,000 0,0211771 0,03150976 ! cyclase activity GO:0009975 21 21 0,000 0,0211771 0,03149664 ! intramolecular transferase activity GO:0016866 22 21 0,000 0,0211771 0,03148352 ! negative regulation of cytokine production GO:0001818 21 21 0,000 0,0211771 0,03147042 ! fatty acid binding GO:0005504 21 21 0,000 0,0211771 0,03145733 ! gut development GO:0048565 21 21 0,000 0,0211771 0,03144425 ! acetyl-CoA catabolic process GO:0046356 21 21 0,000 0,0211771 0,03143118 GO:0006099|tricarboxylic acid cycle, ! phosphoinositide phospholipase C activity GO:0004435 21 21 0,000 0,0211771 0,03141812 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! protein tetramerization GO:0051262 22 21 0,000 0,0211771 0,03140508 ! regulation of microtubule polymerization or depolymerization GO:0031110 23 21 0,000 0,0211771 0,03139204 ! positive regulation of fibroblast proliferation GO:0048146 22 21 0,000 0,0211771 0,03137901 ! sulfur amino acid metabolic process GO:0000096 22 21 0,000 0,0211771 0,031366 ! voltage-gated anion channel activity GO:0008308 21 21 0,000 0,0211771 0,03135299 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,0211771 0,03134 ! cellular polysaccharide biosynthetic process GO:0033692 21 21 0,000 0,0211771 0,03132702 ! positive regulation of JAK-STAT cascade GO:0046427 22 21 0,000 0,0211771 0,03131405 ! sterol binding GO:0032934 21 21 0,000 0,0211771 0,03130109 ! regulation of chemotaxis GO:0050920 21 21 0,000 0,0211771 0,03128814 ! regulation of carbohydrate metabolic process GO:0006109 22 21 0,000 0,0211771 0,0312752 GO:0010675|regulation of cellular carbohydrate metabolic process, ! superoxide metabolic process GO:0006801 21 21 0,000 0,0211771 0,03126227 ! calcium-dependent cell-cell adhesion GO:0016339 21 21 0,000 0,0211771 0,03124935 ! phosphatase binding GO:0019902 22 21 0,000 0,0211771 0,03123644 ! NAD+ ADP-ribosyltransferase activity GO:0003950 21 21 0,000 0,0211771 0,03122354 ! positive regulation of cytoskeleton organization GO:0051495 21 21 0,000 0,0211771 0,03121066 ! negative regulation of DNA replication GO:0008156 25 21 0,000 0,0211771 0,03119778 ! vesicle targeting GO:0006903 22 21 0,000 0,0211771 0,03118492 ! vesicle docking during exocytosis GO:0006904 21 21 0,000 0,0211771 0,03117206 ! RNA-dependent ATPase activity GO:0008186 21 21 0,000 0,0211771 0,03115922 ! renal system process GO:0003014 22 21 0,000 0,0211771 0,03114639 ! base-excision repair GO:0006284 21 21 0,000 0,0211771 0,03113356 ! positive regulation of leukocyte mediated immunity GO:0002705 25 21 0,000 0,0211771 0,03112075 GO:0002708|positive regulation of lymphocyte mediated immunity, ! nuclear-transcribed mRNA catabolic process GO:0000956 22 21 0,000 0,0211771 0,03110795 ! fatty acid transport GO:0015908 21 21 0,000 0,0211771 0,03109516 ! sarcoplasmic reticulum GO:0016529 22 21 0,000 0,0211771 0,03108238 ! positive regulation of tissue remodeling GO:0034105 22 21 0,000 0,0211771 0,03106961 ! collagen catabolic process GO:0030574 21 21 0,000 0,0211771 0,03105685 ! pyrimidine nucleotide biosynthetic process GO:0006221 25 21 0,000 0,0211771 0,0310441 ! regulation of multi-organism process GO:0043900 21 21 0,000 0,0211771 0,03103136 ! ubiquitin-specific protease activity GO:0004843 22 21 0,000 0,0211771 0,03101863 ! positive regulation of DNA replication GO:0045740 23 22 0,000 0,02217502 0,03246699 ! site of polarized growth GO:0030427 23 22 0,000 0,02217502 0,03245368 ! positive regulation of cell adhesion GO:0045785 23 22 0,000 0,02217502 0,03244039 ! leukocyte adhesion GO:0007159 27 22 0,000 0,02217502 0,0324271 ! glutamate signaling pathway GO:0007215 25 22 0,000 0,02217502 0,03241383 ! potassium channel regulator activity GO:0015459 24 22 0,000 0,02217502 0,03240057 ! peroxisome organization GO:0007031 22 22 0,000 0,02217502 0,03238731 ! cellular response to reactive oxygen species GO:0034614 22 22 0,000 0,02217502 0,03237407 ! polysaccharide catabolic process GO:0000272 22 22 0,000 0,02217502 0,03236084 ! response to starvation GO:0042594 23 22 0,000 0,02217502 0,03234762 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 22 22 0,000 0,02217502 0,03233442 ! coenzyme catabolic process GO:0009109 22 22 0,000 0,02217502 0,03232122 ! regulation of insulin secretion GO:0050796 23 22 0,000 0,02217502 0,03230803 ! membrane depolarization GO:0051899 24 22 0,000 0,02217502 0,03229485 ! somitogenesis GO:0001756 23 22 0,000 0,02217502 0,03228169 ! regulation of cytokine secretion GO:0050707 22 22 0,000 0,02217502 0,03226853 ! natural killer cell activation GO:0030101 22 22 0,000 0,02217502 0,03225539 ! positive regulation of B cell activation GO:0050871 26 22 0,000 0,02217502 0,03224226 ! aromatic amino acid family metabolic process GO:0009072 25 22 0,000 0,02217502 0,03222913 ! basal plasma membrane GO:0009925 22 22 0,000 0,02217502 0,03221602 GO:0045178|basal part of cell, ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 22 22 0,000 0,02217502 0,03220292 ! camera-type eye morphogenesis GO:0048593 25 22 0,000 0,02217502 0,03218983 ! telomere organization GO:0032200 23 22 0,000 0,02217502 0,03217675 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 22 22 0,000 0,02217502 0,03216368 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 22 0,000 0,02217502 0,03215062 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 22 22 0,000 0,02217502 0,03213757 GO:0016444|somatic cell DNA recombination, ! cortical actin cytoskeleton GO:0030864 22 22 0,000 0,02217502 0,03212454 ! initiation of viral infection GO:0019059 22 22 0,000 0,02217502 0,03211151 ! RNA polymerase complex GO:0030880 23 22 0,000 0,02217502 0,03209849 ! regulation of neurotransmitter transport GO:0051588 23 22 0,000 0,02217502 0,03208549 ! macromolecular complex disassembly GO:0032984 23 22 0,000 0,02217502 0,03207249 ! response to ethanol GO:0045471 25 22 0,000 0,02217502 0,03205951 ! syntaxin binding GO:0019905 23 22 0,000 0,02217502 0,03204653 ! regulation of nitric oxide biosynthetic process GO:0045428 22 22 0,000 0,02217502 0,03203357 ! digestive system process GO:0022600 24 22 0,000 0,02217502 0,03202062 ! neurotransmitter transporter activity GO:0005326 22 22 0,000 0,02217502 0,03200767 ! autophagy GO:0006914 24 22 0,000 0,02217502 0,03199474 ! carbohydrate kinase activity GO:0019200 22 22 0,000 0,02217502 0,03198182 ! neuropeptide hormone activity GO:0005184 23 22 0,000 0,02217502 0,03196891 ! negative regulation of phosphorylation GO:0042326 26 22 0,000 0,02217502 0,03195601 ! transaminase activity GO:0008483 23 22 0,000 0,02217502 0,03194312 ! sarcoplasm GO:0016528 23 22 0,000 0,02217502 0,03193023 ! cellular response to nutrient levels GO:0031669 23 22 0,000 0,02217502 0,03191736 ! positive regulation of nuclear division GO:0051785 22 22 0,000 0,02217502 0,03190451 GO:0045840|positive regulation of mitosis, ! nerve-nerve synaptic transmission GO:0007270 25 22 0,000 0,02217502 0,03189166 ! small conjugating protein-specific protease activity GO:0019783 24 22 0,000 0,02217502 0,03187882 ! pyrimidine nucleoside metabolic process GO:0006213 25 22 0,000 0,02217502 0,03186599 ! solute:cation antiporter activity GO:0015298 22 22 0,000 0,02217502 0,03185317 ! translational initiation GO:0006413 23 23 0,000 0,02317198 0,03327187 ! NF-kappaB binding GO:0051059 23 23 0,000 0,02317198 0,0332585 ! vesicle docking GO:0048278 23 23 0,000 0,02317198 0,03324514 ! muscle myosin complex GO:0005859 25 23 0,000 0,02317198 0,03323179 ! vasculogenesis GO:0001570 25 23 0,000 0,02317198 0,03321845 ! regulation of innate immune response GO:0045088 23 23 0,000 0,02317198 0,03320512 ! androgen receptor binding GO:0050681 23 23 0,000 0,02317198 0,0331918 ! positive regulation of epithelial cell proliferation GO:0050679 24 23 0,000 0,02317198 0,03317849 ! sperm motility GO:0030317 23 23 0,000 0,02317198 0,03316519 ! response to corticosteroid stimulus GO:0031960 24 23 0,000 0,02317198 0,0331519 ! barbed-end actin filament capping GO:0051016 23 23 0,000 0,02317198 0,03313863 GO:0051693|actin filament capping, ! negative regulation of phosphorus metabolic process GO:0010563 27 23 0,000 0,02317198 0,03312536 GO:0045936|negative regulation of phosphate metabolic process, ! osteoblast differentiation GO:0001649 24 23 0,000 0,02317198 0,03311211 ! regulation of behavior GO:0050795 23 23 0,000 0,02317198 0,03309886 ! cardiac muscle tissue morphogenesis GO:0055008 24 23 0,000 0,02317198 0,03308563 GO:0060415|muscle tissue morphogenesis, ! cyclic nucleotide biosynthetic process GO:0009190 23 23 0,000 0,02317198 0,0330724 ! leukotriene metabolic process GO:0006691 23 23 0,000 0,02317198 0,03305919 ! positive regulation of T cell differentiation GO:0045582 27 23 0,000 0,02317198 0,03304599 ! glycolipid metabolic process GO:0006664 23 23 0,000 0,02317198 0,03303279 ! regulation of ARF GTPase activity GO:0032312 26 23 0,000 0,02317198 0,03301961 ! pallium development GO:0021543 23 23 0,000 0,02317198 0,03300644 ! GABA receptor activity GO:0016917 24 23 0,000 0,02317198 0,03299328 ! positive regulation of MAPKKK cascade GO:0043410 30 23 0,000 0,02317198 0,03298013 ! regulation of response to biotic stimulus GO:0002831 23 23 0,000 0,02317198 0,03296699 ! MHC class II receptor activity GO:0032395 23 23 0,000 0,02317198 0,03295386 ! nicotinamide metabolic process GO:0006769 23 23 0,000 0,02317198 0,03294074 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of neuron differentiation GO:0045665 23 23 0,000 0,02317198 0,03292764 ! aspartate family amino acid metabolic process GO:0009066 24 23 0,000 0,02317198 0,03291454 ! cell surface binding GO:0043498 25 23 0,000 0,02317198 0,03290145 ! collagen binding GO:0005518 27 23 0,000 0,02317198 0,03288837 ! insulin-like growth factor binding GO:0005520 23 23 0,000 0,02317198 0,03287531 ! regulation of amine transport GO:0051952 23 23 0,000 0,02317198 0,03286225 ! tissue homeostasis GO:0001894 24 23 0,000 0,02317198 0,03284921 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 25 23 0,000 0,02317198 0,03283617 ! protein import into nucleus, translocation GO:0000060 25 23 0,000 0,02317198 0,03282315 ! gluconeogenesis GO:0006094 24 23 0,000 0,02317198 0,03281013 ! iron ion transport GO:0006826 24 23 0,000 0,02317198 0,03279713 ! nucleotide-excision repair, DNA damage removal GO:0000718 24 23 0,000 0,02317198 0,03278413 ! N-acetylglucosamine metabolic process GO:0006044 23 23 0,000 0,02317198 0,03277115 ! molting cycle process GO:0022404 23 23 0,000 0,02317198 0,03275818 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! circadian rhythm GO:0007623 24 23 0,000 0,02317198 0,03274521 ! insulin receptor signaling pathway GO:0008286 28 23 0,000 0,02317198 0,03273226 ! multicellular organismal response to stress GO:0033555 23 23 0,000 0,02317198 0,03271932 ! immune response-activating signal transduction GO:0002757 29 23 0,000 0,02317198 0,03270638 ! lymphocyte proliferation GO:0046651 29 23 0,000 0,02317198 0,03269346 ! fibroblast growth factor receptor signaling pathway GO:0008543 24 23 0,000 0,02317198 0,03268055 ! regulation of bone mineralization GO:0030500 25 23 0,000 0,02317198 0,03266765 ! single-stranded RNA binding GO:0003727 24 23 0,000 0,02317198 0,03265476 ! brush border GO:0005903 25 23 0,000 0,02317198 0,03264187 ! caveola GO:0005901 24 23 0,000 0,02317198 0,032629 ! gap junction GO:0005921 23 23 0,000 0,02317198 0,03261614 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 25 24 0,000 0,024168 0,0340047 ! regulation of transmembrane transport GO:0034762 24 24 0,000 0,024168 0,03399131 ! heterotrimeric G-protein complex GO:0005834 24 24 0,000 0,024168 0,03397793 ! protein amino acid acylation GO:0043543 26 24 0,000 0,024168 0,03396455 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 24 0,000 0,024168 0,03395119 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 25 24 0,000 0,024168 0,03393784 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,024168 0,0339245 ! MHC class I protein complex GO:0042612 24 24 0,000 0,024168 0,03391117 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 24 24 0,000 0,024168 0,03389785 ! G-protein chemoattractant receptor activity GO:0001637 24 24 0,000 0,024168 0,03388454 GO:0004950|chemokine receptor activity, ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 24 24 0,000 0,024168 0,03387124 ! early endosome membrane GO:0031901 26 24 0,000 0,024168 0,03385796 ! ARF GTPase activator activity GO:0008060 27 24 0,000 0,024168 0,03384468 ! hydrogen peroxide metabolic process GO:0042743 24 24 0,000 0,024168 0,03383141 ! immunoglobulin production GO:0002377 28 24 0,000 0,024168 0,03381815 GO:0002440|production of molecular mediator of immune response, ! lipid kinase activity GO:0001727 26 24 0,000 0,024168 0,03380491 ! positive regulation of protein secretion GO:0050714 26 24 0,000 0,024168 0,03379167 ! MHC class I receptor activity GO:0032393 24 24 0,000 0,024168 0,03377845 ! RNA splicing factor activity, transesterification mechanism GO:0031202 24 24 0,000 0,024168 0,03376523 ! fat-soluble vitamin metabolic process GO:0006775 24 24 0,000 0,024168 0,03375203 ! regulation of osteoblast differentiation GO:0045667 27 24 0,000 0,024168 0,03373883 ! cellular alkene metabolic process GO:0043449 24 24 0,000 0,024168 0,03372565 ! somatic diversification of immune receptors GO:0002200 24 24 0,000 0,024168 0,03371247 ! calcium-dependent phospholipid binding GO:0005544 24 24 0,000 0,024168 0,03369931 ! positive regulation of JUN kinase activity GO:0043507 24 24 0,000 0,024168 0,03368616 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 26 24 0,000 0,024168 0,03367301 ! Z disc GO:0030018 27 24 0,000 0,024168 0,03365988 ! negative regulation of lymphocyte activation GO:0051250 24 24 0,000 0,024168 0,03364676 ! regulation of fibroblast proliferation GO:0048145 25 24 0,000 0,024168 0,03363364 ! alkaloid metabolic process GO:0009820 24 24 0,000 0,024168 0,03362054 ! neuron fate commitment GO:0048663 24 24 0,000 0,024168 0,03360745 ! glucosamine metabolic process GO:0006041 24 24 0,000 0,024168 0,03359437 ! regulation of transcription factor import into nucleus GO:0042990 25 24 0,000 0,024168 0,0335813 ! glucose transport GO:0015758 24 24 0,000 0,024168 0,03356823 ! dendrite development GO:0016358 26 24 0,000 0,024168 0,03355518 ! negative regulation of protein modification process GO:0031400 28 24 0,000 0,024168 0,03354214 ! catechol metabolic process GO:0009712 27 24 0,000 0,024168 0,03352911 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! phospholipase A2 activity GO:0004623 26 24 0,000 0,024168 0,03351609 ! immune response-regulating signal transduction GO:0002764 30 24 0,000 0,024168 0,03350308 ! regulation of production of molecular mediator of immune response GO:0002700 28 24 0,000 0,024168 0,03349008 ! DNA-directed DNA polymerase activity GO:0003887 25 24 0,000 0,024168 0,03347709 ! synaptogenesis GO:0007416 25 24 0,000 0,024168 0,03346411 ! selenium binding GO:0008430 24 24 0,000 0,024168 0,03345114 ! leukocyte proliferation GO:0070661 30 24 0,000 0,024168 0,03343818 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 26 24 0,000 0,024168 0,03342522 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 25 25 0,000 0,02516307 0,03478797 ! RNA export from nucleus GO:0006405 27 25 0,000 0,02516307 0,03477451 ! phenol metabolic process GO:0018958 28 25 0,000 0,02516307 0,03476105 ! myelination GO:0042552 26 25 0,000 0,02516307 0,03474761 ! epidermal growth factor receptor signaling pathway GO:0007173 28 25 0,000 0,02516307 0,03473418 ! actin filament GO:0005884 28 25 0,000 0,02516307 0,03472076 ! hexose transport GO:0008645 25 25 0,000 0,02516307 0,03470735 GO:0015749|monosaccharide transport, ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 27 25 0,000 0,02516307 0,03469395 ! PML body GO:0016605 28 25 0,000 0,02516307 0,03468056 ! regulation of cellular ketone metabolic process GO:0010565 26 25 0,000 0,02516307 0,03466718 ! negative regulation of cell development GO:0010721 28 25 0,000 0,02516307 0,03465381 GO:0050768|negative regulation of neurogenesis, ! regulation of biomineral formation GO:0070167 27 25 0,000 0,02516307 0,03464045 ! cell fate determination GO:0001709 25 25 0,000 0,02516307 0,0346271 ! regulation of oxidoreductase activity GO:0051341 25 25 0,000 0,02516307 0,03461376 ! group transfer coenzyme metabolic process GO:0006752 26 25 0,000 0,02516307 0,03460043 ! hormone transport GO:0009914 26 25 0,000 0,02516307 0,03458712 ! neuromuscular process controlling balance GO:0050885 26 25 0,000 0,02516307 0,03457381 ! porphyrin metabolic process GO:0006778 27 25 0,000 0,02516307 0,03456051 GO:0033013|tetrapyrrole metabolic process, ! blastocyst development GO:0001824 25 25 0,000 0,02516307 0,03454722 ! regulation of JUN kinase activity GO:0043506 25 25 0,000 0,02516307 0,03453395 ! cell adhesion molecule binding GO:0050839 27 25 0,000 0,02516307 0,03452068 ! negative regulation of actin filament depolymerization GO:0030835 25 25 0,000 0,02516307 0,03450742 ! acetyl-CoA metabolic process GO:0006084 25 25 0,000 0,02516307 0,03449417 ! membrane lipid catabolic process GO:0046466 26 25 0,000 0,02516307 0,03448094 ! zinc ion transport GO:0006829 26 25 0,000 0,02516307 0,03446771 ! heterochromatin GO:0000792 26 25 0,000 0,02516307 0,0344545 ! cellular iron ion homeostasis GO:0006879 25 25 0,000 0,02516307 0,03444129 ! phototransduction GO:0007602 25 25 0,000 0,02516307 0,03442809 ! keratinization GO:0031424 26 25 0,000 0,02516307 0,03441491 ! spinal cord development GO:0021510 25 25 0,000 0,02516307 0,03440173 ! cyclin-dependent protein kinase activity GO:0004693 26 25 0,000 0,02516307 0,03438857 ! regulation of smooth muscle contraction GO:0006940 28 25 0,000 0,02516307 0,03437541 ! response to toxin GO:0009636 25 25 0,000 0,02516307 0,03436227 ! regulation of peptide secretion GO:0002791 26 25 0,000 0,02516307 0,03434913 ! determination of left/right symmetry GO:0007368 25 25 0,000 0,02516307 0,03433601 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 25 0,000 0,02516307 0,03432289 ! regulation of interleukin-6 production GO:0032675 25 25 0,000 0,02516307 0,03430978 ! voltage-gated calcium channel activity GO:0005245 28 25 0,000 0,02516307 0,03429669 ! phospholipid transport GO:0015914 26 25 0,000 0,02516307 0,0342836 ! protein localization in mitochondrion GO:0070585 26 25 0,000 0,02516307 0,03427053 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 25 25 0,000 0,02516307 0,03425746 ! regulation of microtubule cytoskeleton organization GO:0070507 27 25 0,000 0,02516307 0,03424441 ! ethanolamine and derivative metabolic process GO:0042439 28 25 0,000 0,02516307 0,03423136 ! small nuclear ribonucleoprotein complex GO:0030532 25 25 0,000 0,02516307 0,03421833 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 25 25 0,000 0,02516307 0,0342053 ! negative regulation of transcription regulator activity GO:0090048 26 25 0,000 0,02516307 0,03419229 GO:0043433|negative regulation of transcription factor activity, ! acetylgalactosaminyltransferase activity GO:0008376 27 25 0,000 0,02516307 0,03417928 ! solute:solute antiporter activity GO:0015300 26 26 0,000 0,02615719 0,0355161 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 27 26 0,000 0,02615719 0,0355026 ! regeneration GO:0031099 26 26 0,000 0,02615719 0,03548911 ! cholesterol homeostasis GO:0042632 26 26 0,000 0,02615719 0,03547563 GO:0055092|sterol homeostasis, ! peptidyl-tyrosine phosphorylation GO:0018108 27 26 0,000 0,02615719 0,03546216 ! ureteric bud development GO:0001657 26 26 0,000 0,02615719 0,03544871 ! neural crest cell development GO:0014032 26 26 0,000 0,02615719 0,03543526 GO:0014033|neural crest cell differentiation, ! negative regulation of protein kinase cascade GO:0010741 27 26 0,000 0,02615719 0,03542182 ! cellular response to oxidative stress GO:0034599 26 26 0,000 0,02615719 0,03540839 ! lipid oxidation GO:0034440 26 26 0,000 0,02615719 0,03539497 GO:0019395|fatty acid oxidation, ! positive regulation of lymphocyte differentiation GO:0045621 30 26 0,000 0,02615719 0,03538157 ! pyridine nucleotide metabolic process GO:0019362 26 26 0,000 0,02615719 0,03536817 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 26 26 0,000 0,02615719 0,03535478 ! carboxy-lyase activity GO:0016831 26 26 0,000 0,02615719 0,03534141 ! myeloid leukocyte activation GO:0002274 27 26 0,000 0,02615719 0,03532804 ! negative regulation of neuron apoptosis GO:0043524 26 26 0,000 0,02615719 0,03531468 ! negative regulation of catabolic process GO:0009895 28 26 0,000 0,02615719 0,03530134 ! lysine N-acetyltransferase activity GO:0004468 26 26 0,000 0,02615719 0,035288 GO:0004402|histone acetyltransferase activity, ! regulation of actin filament depolymerization GO:0030834 26 26 0,000 0,02615719 0,03527467 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,02615719 0,03526136 ! determination of bilateral symmetry GO:0009855 26 26 0,000 0,02615719 0,03524805 GO:0009799|determination of symmetry, ! regulation of cellular catabolic process GO:0031329 28 26 0,000 0,02615719 0,03523476 ! pyruvate metabolic process GO:0006090 27 26 0,000 0,02615719 0,03522147 ! cellular component assembly involved in morphogenesis GO:0010927 26 26 0,000 0,02615719 0,03520819 ! histone methyltransferase activity GO:0042054 29 26 0,000 0,02615719 0,03519493 ! regulation of endothelial cell proliferation GO:0001936 27 26 0,000 0,02615719 0,03518167 ! chemokine binding GO:0019956 26 26 0,000 0,02615719 0,03516843 ! fat cell differentiation GO:0045444 26 26 0,000 0,02615719 0,03515519 ! receptor metabolic process GO:0043112 28 26 0,000 0,02615719 0,03514196 ! nucleotide kinase activity GO:0019201 30 26 0,000 0,02615719 0,03512875 ! histone deacetylase complex GO:0000118 27 26 0,000 0,02615719 0,03511554 ! phospholipase C activity GO:0004629 27 26 0,000 0,02615719 0,03510234 ! response to endoplasmic reticulum stress GO:0034976 29 26 0,000 0,02615719 0,03508916 ! cellular response to extracellular stimulus GO:0031668 27 26 0,000 0,02615719 0,03507598 ! negative regulation of leukocyte activation GO:0002695 26 26 0,000 0,02615719 0,03506281 ! receptor regulator activity GO:0030545 26 26 0,000 0,02615719 0,03504966 ! galactosyltransferase activity GO:0008378 27 26 0,000 0,02615719 0,03503651 ! positive regulation of immune effector process GO:0002699 30 26 0,000 0,02615719 0,03502337 ! mRNA catabolic process GO:0006402 28 27 0,000 0,02715037 0,03633957 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 28 27 0,000 0,02715037 0,03632595 ! actomyosin structure organization GO:0031032 28 27 0,000 0,02715037 0,03631235 ! nucleotide receptor activity, G-protein coupled GO:0001608 27 27 0,000 0,02715037 0,03629875 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! iron ion homeostasis GO:0055072 27 27 0,000 0,02715037 0,03628517 ! lipoprotein binding GO:0008034 29 27 0,000 0,02715037 0,03627159 ! deaminase activity GO:0019239 27 27 0,000 0,02715037 0,03625803 ! mesoderm formation GO:0001707 28 27 0,000 0,02715037 0,03624448 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 27 27 0,000 0,02715037 0,03623093 ! phospholipid transporter activity GO:0005548 29 27 0,000 0,02715037 0,0362174 ! mitotic sister chromatid segregation GO:0000070 27 27 0,000 0,02715037 0,03620387 ! regulation of smooth muscle cell proliferation GO:0048660 27 27 0,000 0,02715037 0,03619036 ! integrin complex GO:0008305 28 27 0,000 0,02715037 0,03617686 ! nuclear chromatin GO:0000790 28 27 0,000 0,02715037 0,03616336 ! collagen metabolic process GO:0032963 27 27 0,000 0,02715037 0,03614988 ! post-embryonic development GO:0009791 29 27 0,000 0,02715037 0,0361364 ! antigen processing and presentation of peptide antigen GO:0048002 28 27 0,000 0,02715037 0,03612294 ! ovulation cycle process GO:0022602 27 27 0,000 0,02715037 0,03610949 ! SNARE binding GO:0000149 28 27 0,000 0,02715037 0,03609604 ! biogenic amine biosynthetic process GO:0042401 28 27 0,000 0,02715037 0,03608261 ! spindle pole GO:0000922 28 27 0,000 0,02715037 0,03606919 ! trans-Golgi network GO:0005802 29 28 0,000 0,0281426 0,03737346 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 28 0,000 0,0281426 0,03735957 ! cholesterol transport GO:0030301 28 28 0,000 0,0281426 0,03734568 GO:0015918|sterol transport, ! thyroid hormone receptor binding GO:0046966 29 28 0,000 0,0281426 0,03733181 ! dynein complex GO:0030286 29 28 0,000 0,0281426 0,03731795 ! formation of primary germ layer GO:0001704 29 28 0,000 0,0281426 0,03730409 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 30 28 0,000 0,0281426 0,03729025 ! ovulation cycle GO:0042698 28 28 0,000 0,0281426 0,03727642 ! peptidyl-tyrosine modification GO:0018212 29 28 0,000 0,0281426 0,0372626 ! deoxyribonuclease activity GO:0004536 28 28 0,000 0,0281426 0,03724879 ! cofactor catabolic process GO:0051187 30 28 0,000 0,0281426 0,03723499 ! negative regulation of actin filament polymerization GO:0030837 28 28 0,000 0,0281426 0,0372212 ! cortical cytoskeleton GO:0030863 29 28 0,000 0,0281426 0,03720742 ! icosanoid biosynthetic process GO:0046456 29 28 0,000 0,0281426 0,03719365 ! amino sugar metabolic process GO:0006040 28 28 0,000 0,0281426 0,03717989 ! membrane docking GO:0022406 28 28 0,000 0,0281426 0,03716614 ! sister chromatid segregation GO:0000819 28 28 0,000 0,0281426 0,0371524 ! detection of light stimulus involved in sensory perception GO:0050962 28 28 0,000 0,0281426 0,03713867 GO:0050908|detection of light stimulus involved in visual perception, ! cell junction assembly GO:0034329 30 28 0,000 0,0281426 0,03712495 ! complement activation, classical pathway GO:0006958 31 28 0,000 0,0281426 0,03711124 ! ER-nuclear signaling pathway GO:0006984 31 28 0,000 0,0281426 0,03709754 ! multicellular organismal catabolic process GO:0044243 28 28 0,000 0,0281426 0,03708385 ! response to mechanical stimulus GO:0009612 28 28 0,000 0,0281426 0,03707017 ! ensheathment of neurons GO:0007272 29 28 0,000 0,0281426 0,0370565 GO:0008366|axon ensheathment, ! DNA polymerase activity GO:0034061 29 28 0,000 0,0281426 0,03704284 ! calcium-mediated signaling GO:0019722 28 28 0,000 0,0281426 0,03702919 ! neurotransmitter secretion GO:0007269 29 28 0,000 0,0281426 0,03701555 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 28 28 0,000 0,0281426 0,03700193 ! glycogen metabolic process GO:0005977 29 28 0,000 0,0281426 0,03698831 ! RNA helicase activity GO:0003724 28 28 0,000 0,0281426 0,0369747 ! Rho GTPase activator activity GO:0005100 32 28 0,000 0,0281426 0,0369611 ! protein kinase inhibitor activity GO:0004860 28 28 0,000 0,0281426 0,03694751 ! symbiosis, encompassing mutualism through parasitism GO:0044403 32 28 0,000 0,0281426 0,03693393 ! transferase activity, transferring nitrogenous groups GO:0016769 30 29 0,000 0,02913389 0,03822084 ! spliceosomal snRNP biogenesis GO:0000387 30 29 0,000 0,02913389 0,0382068 ! odontogenesis of dentine-containing tooth GO:0042475 30 29 0,000 0,02913389 0,03819277 ! scavenger receptor activity GO:0005044 30 29 0,000 0,02913389 0,03817876 ! spindle organization GO:0007051 30 29 0,000 0,02913389 0,03816475 ! mesoderm morphogenesis GO:0048332 30 29 0,000 0,02913389 0,03815076 ! male gonad development GO:0008584 29 29 0,000 0,02913389 0,03813677 ! response to organic cyclic substance GO:0014070 31 29 0,000 0,02913389 0,0381228 ! negative regulation of MAP kinase activity GO:0043407 30 29 0,000 0,02913389 0,03810883 ! sterol biosynthetic process GO:0016126 30 29 0,000 0,02913389 0,03809488 ! endocytic vesicle GO:0030139 29 29 0,000 0,02913389 0,03808094 ! Rho GTPase binding GO:0017048 32 29 0,000 0,02913389 0,038067 ! serine family amino acid metabolic process GO:0009069 30 29 0,000 0,02913389 0,03805308 ! fatty acid catabolic process GO:0009062 30 29 0,000 0,02913389 0,03803916 ! regulation of calcium ion transport GO:0051924 32 29 0,000 0,02913389 0,03802526 ! negative regulation of protein polymerization GO:0032272 29 29 0,000 0,02913389 0,03801137 ! glucan metabolic process GO:0044042 30 29 0,000 0,02913389 0,03799749 GO:0006073|cellular glucan metabolic process, ! regulation of synaptic plasticity GO:0048167 29 29 0,000 0,02913389 0,03798361 ! proteoglycan metabolic process GO:0006029 30 29 0,000 0,02913389 0,03796975 ! xenobiotic metabolic process GO:0006805 29 29 0,000 0,02913389 0,0379559 ! negative regulation of response to external stimulus GO:0032102 29 29 0,000 0,02913389 0,03794205 ! positive regulation of T cell proliferation GO:0042102 33 29 0,000 0,02913389 0,03792822 ! steroid dehydrogenase activity GO:0016229 29 29 0,000 0,02913389 0,0379144 ! regulation of protein import into nucleus GO:0042306 30 29 0,000 0,02913389 0,03790059 ! clathrin coated vesicle membrane GO:0030665 32 29 0,000 0,02913389 0,03788679 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 30 29 0,000 0,02913389 0,03787299 ! cytosolic small ribosomal subunit GO:0022627 29 29 0,000 0,02913389 0,03785921 ! detection of visible light GO:0009584 29 29 0,000 0,02913389 0,03784544 ! tumor necrosis factor receptor superfamily binding GO:0032813 29 29 0,000 0,02913389 0,03783168 ! acetylglucosaminyltransferase activity GO:0008375 30 29 0,000 0,02913389 0,03781793 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,02913389 0,03780418 ! gene silencing GO:0016458 29 29 0,000 0,02913389 0,03779045 ! hormone binding GO:0042562 30 30 0,000 0,03012423 0,03906087 ! negative regulation of DNA metabolic process GO:0051053 34 30 0,000 0,03012423 0,03904669 ! inner ear morphogenesis GO:0042472 31 30 0,000 0,03012423 0,03903252 ! GPI anchor biosynthetic process GO:0006506 32 30 0,000 0,03012423 0,03901836 ! acrosomal vesicle GO:0001669 32 30 0,000 0,03012423 0,03900422 ! negative regulation of DNA binding GO:0043392 31 30 0,000 0,03012423 0,03899008 ! triglyceride metabolic process GO:0006641 31 30 0,000 0,03012423 0,03897595 ! erythrocyte differentiation GO:0030218 32 30 0,000 0,03012423 0,03896184 ! glutamate receptor activity GO:0008066 33 30 0,000 0,03012423 0,03894773 ! kinase inhibitor activity GO:0019210 30 30 0,000 0,03012423 0,03893363 ! ceramide metabolic process GO:0006672 30 30 0,000 0,03012423 0,03891955 ! cell fate specification GO:0001708 31 30 0,000 0,03012423 0,03890547 ! hexose biosynthetic process GO:0019319 32 30 0,000 0,03012423 0,03889141 ! negative regulation of hydrolase activity GO:0051346 32 30 0,000 0,03012423 0,03887735 ! PDZ domain binding GO:0030165 32 30 0,000 0,03012423 0,03886331 ! AP-type membrane coat adaptor complex GO:0030119 31 30 0,000 0,03012423 0,03884927 GO:0030131|clathrin adaptor complex, ! negative regulation of cell activation GO:0050866 31 30 0,000 0,03012423 0,03883525 ! negative regulation of protein transport GO:0051224 30 30 0,000 0,03012423 0,03882123 ! negative regulation of protein complex assembly GO:0031333 30 30 0,000 0,03012423 0,03880723 ! regulation of JAK-STAT cascade GO:0046425 32 30 0,000 0,03012423 0,03879323 ! drug binding GO:0008144 30 30 0,000 0,03012423 0,03877925 ! multicellular organismal macromolecule metabolic process GO:0044259 30 30 0,000 0,03012423 0,03876527 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 33 30 0,000 0,03012423 0,03875131 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,03012423 0,03873735 ! regulation of systemic arterial blood pressure GO:0003073 32 30 0,000 0,03012423 0,03872341 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 31 30 0,000 0,03012423 0,03870947 ! aminopeptidase activity GO:0004177 32 30 0,000 0,03012423 0,03869555 ! detection of light stimulus GO:0009583 30 30 0,000 0,03012423 0,03868164 ! L-amino acid transmembrane transporter activity GO:0015179 30 30 0,000 0,03012423 0,03866773 ! regulation of microtubule-based process GO:0032886 32 30 0,000 0,03012423 0,03865384 ! meiosis I GO:0007127 31 31 0,000 0,03111363 0,03990904 ! negative regulation of cell adhesion GO:0007162 33 31 0,000 0,03111363 0,03989471 ! striated muscle cell differentiation GO:0051146 31 31 0,000 0,03111363 0,03988039 ! GPI anchor metabolic process GO:0006505 33 31 0,000 0,03111363 0,03986608 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,03111363 0,03985178 ! spliceosome assembly GO:0000245 32 31 0,000 0,03111363 0,0398375 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 32 31 0,000 0,03111363 0,03982322 GO:0004601|peroxidase activity, ! unsaturated fatty acid biosynthetic process GO:0006636 32 31 0,000 0,03111363 0,03980895 ! NAD or NADH binding GO:0051287 31 31 0,000 0,03111363 0,03979469 ! positive regulation of neurogenesis GO:0050769 32 31 0,000 0,03111363 0,03978044 ! cyclic nucleotide metabolic process GO:0009187 31 31 0,000 0,03111363 0,0397662 ! nucleotide catabolic process GO:0009166 32 31 0,000 0,03111363 0,03975198 ! replication fork GO:0005657 32 31 0,000 0,03111363 0,03973776 ! placenta development GO:0001890 31 31 0,000 0,03111363 0,03972355 ! condensed nuclear chromosome GO:0000794 32 31 0,000 0,03111363 0,03970936 ! regulation of pH GO:0006885 31 31 0,000 0,03111363 0,03969517 ! protein methyltransferase activity GO:0008276 36 31 0,000 0,03111363 0,03968099 ! acute-phase response GO:0006953 32 31 0,000 0,03111363 0,03966682 ! peptide transport GO:0015833 32 31 0,000 0,03111363 0,03965267 ! respiratory gaseous exchange GO:0007585 32 31 0,000 0,03111363 0,03963852 ! Golgi-associated vesicle membrane GO:0030660 34 31 0,000 0,03111363 0,03962439 ! regulation of protein stability GO:0031647 32 31 0,000 0,03111363 0,03961026 ! sarcolemma GO:0042383 33 31 0,000 0,03111363 0,03959614 ! vesicle localization GO:0051648 32 31 0,000 0,03111363 0,03958204 ! microtubule organizing center part GO:0044450 34 31 0,000 0,03111363 0,03956794 ! response to hydrogen peroxide GO:0042542 34 32 0,000 0,03210209 0,04081045 ! DNA helicase activity GO:0003678 34 32 0,000 0,03210209 0,04079593 ! NADP or NADPH binding GO:0050661 33 32 0,000 0,03210209 0,04078142 ! pigment biosynthetic process GO:0046148 34 32 0,000 0,03210209 0,04076691 ! purinergic nucleotide receptor activity GO:0001614 34 32 0,000 0,03210209 0,04075242 GO:0016502|nucleotide receptor activity, ! female gonad development GO:0008585 32 32 0,000 0,03210209 0,04073794 ! late endosome membrane GO:0031902 32 32 0,000 0,03210209 0,04072347 ! positive regulation of cell development GO:0010720 33 32 0,000 0,03210209 0,04070901 ! regulation of Wnt receptor signaling pathway GO:0030111 35 32 0,000 0,03210209 0,04069455 ! hindbrain development GO:0030902 35 32 0,000 0,03210209 0,04068011 ! aerobic respiration GO:0009060 32 32 0,000 0,03210209 0,04066568 ! positive regulation of catabolic process GO:0009896 34 32 0,000 0,03210209 0,04065126 ! regulation of B cell activation GO:0050864 36 32 0,000 0,03210209 0,04063685 ! regulation of muscle development GO:0048634 33 32 0,000 0,03210209 0,04062245 GO:0016202|regulation of striated muscle tissue development, ! cation:sugar symporter activity GO:0005402 32 32 0,000 0,03210209 0,04060806 GO:0005351|sugar:hydrogen symporter activity, ! sphingoid metabolic process GO:0046519 32 32 0,000 0,03210209 0,04059368 ! response to ionizing radiation GO:0010212 33 32 0,000 0,03210209 0,04057931 ! flagellum GO:0019861 32 32 0,000 0,03210209 0,04056495 ! regulation of lymphocyte mediated immunity GO:0002706 36 32 0,000 0,03210209 0,0405506 ! I band GO:0031674 35 32 0,000 0,03210209 0,04053627 ! JAK-STAT cascade GO:0007259 34 32 0,000 0,03210209 0,04052194 ! double-stranded RNA binding GO:0003725 33 32 0,000 0,03210209 0,04050762 ! cellular response to insulin stimulus GO:0032869 37 32 0,000 0,03210209 0,04049331 ! adult locomotory behavior GO:0008344 33 32 0,000 0,03210209 0,04047901 ! pyrimidine nucleotide metabolic process GO:0006220 37 32 0,000 0,03210209 0,04046472 ! positive regulation of transcription factor activity GO:0051091 34 33 0,000 0,03308961 0,04169477 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of secretion GO:0051048 34 33 0,000 0,03308961 0,04168006 ! establishment or maintenance of cell polarity GO:0007163 33 33 0,000 0,03308961 0,04166537 ! platelet alpha granule lumen GO:0031093 34 33 0,000 0,03308961 0,04165068 ! negative regulation of binding GO:0051100 34 33 0,000 0,03308961 0,041636 ! protein targeting to membrane GO:0006612 35 33 0,000 0,03308961 0,04162134 ! vesicle coat GO:0030120 36 33 0,000 0,03308961 0,04160668 ! endoribonuclease activity GO:0004521 34 33 0,000 0,03308961 0,04159204 ! eye morphogenesis GO:0048592 38 33 0,000 0,03308961 0,0415774 ! embryonic organ development GO:0048568 36 33 0,000 0,03308961 0,04156278 ! monosaccharide biosynthetic process GO:0046364 35 33 0,000 0,03308961 0,04154816 ! glial cell differentiation GO:0010001 33 33 0,000 0,03308961 0,04153356 ! cell junction organization GO:0034330 35 33 0,000 0,03308961 0,04151897 ! tissue remodeling GO:0048771 35 33 0,000 0,03308961 0,04150438 ! segmentation GO:0035282 34 33 0,000 0,03308961 0,04148981 ! steroid hormone receptor binding GO:0035258 33 33 0,000 0,03308961 0,04147525 ! positive regulation of gene-specific transcription GO:0043193 34 33 0,000 0,03308961 0,0414607 ! energy coupled proton transport, down electrochemical gradient GO:0015985 33 33 0,000 0,03308961 0,04144615 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 35 33 0,000 0,03308961 0,04143162 ! hormone biosynthetic process GO:0042446 33 33 0,000 0,03308961 0,0414171 ! androgen receptor signaling pathway GO:0030521 34 33 0,000 0,03308961 0,04140259 ! O-acyltransferase activity GO:0008374 33 33 0,000 0,03308961 0,04138808 ! response to xenobiotic stimulus GO:0009410 33 33 0,000 0,03308961 0,04137359 ! cellular amide metabolic process GO:0043603 34 34 0,000 0,03407618 0,04259225 ! sugar transmembrane transporter activity GO:0051119 34 34 0,000 0,03407618 0,04257734 GO:0015144|carbohydrate transmembrane transporter activity, ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 34 0,000 0,03407618 0,04256245 ! neutral lipid metabolic process GO:0006638 35 34 0,000 0,03407618 0,04254757 GO:0006639|acylglycerol metabolic process, ! lipid homeostasis GO:0055088 34 34 0,000 0,03407618 0,0425327 ! telencephalon development GO:0021537 34 34 0,000 0,03407618 0,04251784 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 35 34 0,000 0,03407618 0,04250298 ! integral to Golgi membrane GO:0030173 34 34 0,000 0,03407618 0,04248814 ! intramolecular oxidoreductase activity GO:0016860 35 34 0,000 0,03407618 0,04247331 ! collagen GO:0005581 35 34 0,000 0,03407618 0,04245849 ! development of primary female sexual characteristics GO:0046545 34 34 0,000 0,03407618 0,04244368 GO:0046660|female sex differentiation, ! DNA-directed RNA polymerase activity GO:0003899 35 34 0,000 0,03407618 0,04242889 GO:0034062|RNA polymerase activity, ! leukocyte chemotaxis GO:0030595 35 34 0,000 0,03407618 0,0424141 GO:0060326|cell chemotaxis, ! sodium channel activity GO:0005272 36 34 0,000 0,03407618 0,04239932 ! spermatid development GO:0007286 34 34 0,000 0,03407618 0,04238455 ! BMP signaling pathway GO:0030509 35 34 0,000 0,03407618 0,04236979 ! specific RNA polymerase II transcription factor activity GO:0003704 35 34 0,000 0,03407618 0,04235504 ! positive regulation of DNA metabolic process GO:0051054 40 35 0,000 0,03506182 0,04356498 ! regulation of intracellular protein transport GO:0033157 37 35 0,000 0,03506182 0,04354983 ! vesicle lumen GO:0031983 37 35 0,000 0,03506182 0,04353468 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! metanephros development GO:0001656 35 35 0,000 0,03506182 0,04351955 ! regulation of action potential in neuron GO:0019228 38 35 0,000 0,03506182 0,04350443 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 39 35 0,000 0,03506182 0,04348932 ! cytokine production GO:0001816 35 35 0,000 0,03506182 0,04347422 ! carbon-carbon lyase activity GO:0016830 35 35 0,000 0,03506182 0,04345913 ! embryonic pattern specification GO:0009880 36 35 0,000 0,03506182 0,04344405 ! regulation of metal ion transport GO:0010959 38 35 0,000 0,03506182 0,04342898 ! energy reserve metabolic process GO:0006112 36 35 0,000 0,03506182 0,04341392 ! response to calcium ion GO:0051592 39 35 0,000 0,03506182 0,04339887 ! phagocytosis GO:0006909 37 35 0,000 0,03506182 0,04338384 ! regulation of ARF protein signal transduction GO:0032012 40 35 0,000 0,03506182 0,04336881 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 37 35 0,000 0,03506182 0,04335379 ! ion transmembrane transport GO:0034220 35 35 0,000 0,03506182 0,04333879 ! neuropeptide receptor activity GO:0008188 35 35 0,000 0,03506182 0,04332379 ! oxygen binding GO:0019825 36 35 0,000 0,03506182 0,0433088 ! regulation of leukocyte mediated immunity GO:0002703 39 35 0,000 0,03506182 0,04329383 ! erythrocyte homeostasis GO:0034101 37 35 0,000 0,03506182 0,04327886 ! peripheral nervous system development GO:0007422 37 35 0,000 0,03506182 0,04326391 ! female gamete generation GO:0007292 38 35 0,000 0,03506182 0,04324896 ! polyol metabolic process GO:0019751 36 35 0,000 0,03506182 0,04323403 ! negative regulation of adenylate cyclase activity GO:0007194 38 36 0,000 0,03604652 0,0444329 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of hormone secretion GO:0046883 38 36 0,000 0,03604652 0,04441757 ! monocarboxylic acid binding GO:0033293 37 36 0,000 0,03604652 0,04440224 ! polysaccharide biosynthetic process GO:0000271 36 36 0,000 0,03604652 0,04438693 ! regulation of axonogenesis GO:0050770 39 36 0,000 0,03604652 0,04437163 ! glycerol ether metabolic process GO:0006662 37 36 0,000 0,03604652 0,04435634 ! regulation of proteolysis GO:0030162 37 36 0,000 0,03604652 0,04434106 ! integral to endoplasmic reticulum membrane GO:0030176 36 36 0,000 0,03604652 0,04432579 ! regulation of adaptive immune response GO:0002819 40 36 0,000 0,03604652 0,04431054 ! oxidoreduction coenzyme metabolic process GO:0006733 37 36 0,000 0,03604652 0,04429529 ! isoprenoid metabolic process GO:0006720 37 36 0,000 0,03604652 0,04428005 ! spermatid differentiation GO:0048515 36 36 0,000 0,03604652 0,04426482 ! phosphoinositide biosynthetic process GO:0046489 38 36 0,000 0,03604652 0,04424961 ! ER to Golgi vesicle-mediated transport GO:0006888 36 36 0,000 0,03604652 0,0442344 ! condensed chromosome kinetochore GO:0000777 37 36 0,000 0,03604652 0,04421921 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 38 36 0,000 0,03604652 0,04420402 ! neuropeptide binding GO:0042923 36 36 0,000 0,03604652 0,04418885 ! organic anion transport GO:0015711 37 36 0,000 0,03604652 0,04417368 ! carbohydrate homeostasis GO:0033500 38 36 0,000 0,03604652 0,04415853 GO:0042593|glucose homeostasis, ! complement activation GO:0006956 39 36 0,000 0,03604652 0,04414338 ! antigen binding GO:0003823 36 36 0,000 0,03604652 0,04412825 ! extrinsic to plasma membrane GO:0019897 36 36 0,000 0,03604652 0,04411313 ! cytokinesis GO:0000910 40 36 0,000 0,03604652 0,04409802 ! coated pit GO:0005905 42 36 0,000 0,03604652 0,04408291 ! positive regulation of leukocyte proliferation GO:0070665 40 36 0,000 0,03604652 0,04406782 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein amino acid N-linked glycosylation GO:0006487 40 37 0,000 0,03703028 0,045255 ! ribonucleoside metabolic process GO:0009119 43 37 0,000 0,03703028 0,04523952 ! DNA-dependent ATPase activity GO:0008094 39 37 0,000 0,03703028 0,04522405 ! regulation of T cell differentiation GO:0045580 41 37 0,000 0,03703028 0,04520859 ! biopolymer methylation GO:0043414 42 37 0,000 0,03703028 0,04519314 ! intrinsic to Golgi membrane GO:0031228 37 37 0,000 0,03703028 0,0451777 ! protein homooligomerization GO:0051260 38 37 0,000 0,03703028 0,04516227 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 38 37 0,000 0,03703028 0,04514685 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 41 37 0,000 0,03703028 0,04513144 ! regulation of T cell proliferation GO:0042129 41 37 0,000 0,03703028 0,04511604 ! multicellular organismal metabolic process GO:0044236 38 37 0,000 0,03703028 0,04510065 ! amino acid binding GO:0016597 40 37 0,000 0,03703028 0,04508528 ! maintenance of protein location GO:0045185 38 37 0,000 0,03703028 0,04506991 ! maintenance of location in cell GO:0051651 38 37 0,000 0,03703028 0,04505455 ! solute:hydrogen symporter activity GO:0015295 37 37 0,000 0,03703028 0,04503921 ! proton-transporting two-sector ATPase complex GO:0016469 37 37 0,000 0,03703028 0,04502387 ! ear morphogenesis GO:0042471 39 38 0,000 0,0380131 0,04620312 ! odontogenesis GO:0042476 40 38 0,000 0,0380131 0,0461874 ! organic ether metabolic process GO:0018904 39 38 0,000 0,0380131 0,04617169 ! alcohol biosynthetic process GO:0046165 40 38 0,000 0,0380131 0,04615599 ! monovalent inorganic cation homeostasis GO:0055067 39 38 0,000 0,0380131 0,0461403 ! positive regulation of DNA binding GO:0043388 39 38 0,000 0,0380131 0,04612463 ! B cell differentiation GO:0030183 40 38 0,000 0,0380131 0,04610896 ! clathrin coat GO:0030118 43 38 0,000 0,0380131 0,0460933 ! regulation of endocytosis GO:0030100 39 38 0,000 0,0380131 0,04607766 ! dorsal/ventral pattern formation GO:0009953 38 38 0,000 0,0380131 0,04606202 ! cell growth GO:0016049 40 38 0,000 0,0380131 0,0460464 ! positive regulation of defense response GO:0031349 38 38 0,000 0,0380131 0,04603078 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 38 0,000 0,0380131 0,04601518 ! condensed chromosome, centromeric region GO:0000779 39 38 0,000 0,0380131 0,04599958 ! learning GO:0007612 42 38 0,000 0,0380131 0,045984 ! negative regulation of protein complex disassembly GO:0043242 40 38 0,000 0,0380131 0,04596843 ! monocarboxylic acid transport GO:0015718 39 38 0,000 0,0380131 0,04595287 ! endosome transport GO:0016197 40 38 0,000 0,0380131 0,04593732 ! hormone-mediated signaling GO:0009755 39 38 0,000 0,0380131 0,04592178 ! N-methyltransferase activity GO:0008170 42 38 0,000 0,0380131 0,04590625 ! cytosolic large ribosomal subunit GO:0022625 38 38 0,000 0,0380131 0,04589073 ! pigment metabolic process GO:0042440 42 38 0,000 0,0380131 0,04587522 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 38 38 0,000 0,0380131 0,04585972 ! RNA modification GO:0009451 39 38 0,000 0,0380131 0,04584423 ! positive regulation of cell cycle GO:0045787 39 39 0,000 0,03899498 0,04701252 ! regulation of nucleocytoplasmic transport GO:0046822 41 39 0,000 0,03899498 0,04699666 ! Notch signaling pathway GO:0007219 41 39 0,000 0,03899498 0,0469808 ! induction of apoptosis by extracellular signals GO:0008624 39 39 0,000 0,03899498 0,04696495 ! keratin filament GO:0045095 41 39 0,000 0,03899498 0,04694912 ! ER-Golgi intermediate compartment GO:0005793 42 39 0,000 0,03899498 0,0469333 ! peroxisomal membrane GO:0005778 40 39 0,000 0,03899498 0,04691748 GO:0031903|microbody membrane, ! mitochondrial respiratory chain complex I GO:0005747 39 39 0,000 0,03899498 0,04690168 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! actin filament binding GO:0051015 39 39 0,000 0,03899498 0,04688589 ! regulation of protein secretion GO:0050708 41 39 0,000 0,03899498 0,04687011 ! cis-trans isomerase activity GO:0016859 39 39 0,000 0,03899498 0,04685434 ! regulation of cell morphogenesis involved in differentiation GO:0010769 42 39 0,000 0,03899498 0,04683858 ! viral infectious cycle GO:0019058 39 39 0,000 0,03899498 0,04682283 ! mammary gland development GO:0030879 41 39 0,000 0,03899498 0,04680709 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 39 0,000 0,03899498 0,04679136 ! amine receptor activity GO:0008227 41 39 0,000 0,03899498 0,04677564 ! positive regulation of response to external stimulus GO:0032103 39 39 0,000 0,03899498 0,04675994 ! monosaccharide binding GO:0048029 39 39 0,000 0,03899498 0,04674424 ! NADH dehydrogenase (ubiquinone) activity GO:0008137 39 39 0,000 0,03899498 0,04672855 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! phosphotransferase activity, phosphate group as acceptor GO:0016776 44 40 0,000 0,03997594 0,04788798 ! response to estrogen stimulus GO:0043627 41 40 0,000 0,03997594 0,04787192 ! peptide metabolic process GO:0006518 41 40 0,000 0,03997594 0,04785587 ! regulation of Rab protein signal transduction GO:0032483 41 40 0,000 0,03997594 0,04783983 GO:0032313|regulation of Rab GTPase activity, ! T cell differentiation GO:0030217 45 40 0,000 0,03997594 0,04782381 ! regulation of multicellular organism growth GO:0040014 42 40 0,000 0,03997594 0,04780779 ! regulation of gene expression, epigenetic GO:0040029 43 40 0,000 0,03997594 0,04779179 ! neuron migration GO:0001764 42 40 0,000 0,03997594 0,04777579 ! nuclear export GO:0051168 42 40 0,000 0,03997594 0,04775981 ! inositol or phosphatidylinositol kinase activity GO:0004428 42 40 0,000 0,03997594 0,04774384 ! structural constituent of muscle GO:0008307 43 40 0,000 0,03997594 0,04772787 ! gliogenesis GO:0042063 40 40 0,000 0,03997594 0,04771192 ! feeding behavior GO:0007631 40 40 0,000 0,03997594 0,04769598 ! positive regulation of cytokine biosynthetic process GO:0042108 41 40 0,000 0,03997594 0,04768005 ! sulfur compound biosynthetic process GO:0044272 41 40 0,000 0,03997594 0,04766413 ! chromatin remodeling GO:0006338 43 40 0,000 0,03997594 0,04764822 ! response to insulin stimulus GO:0032868 45 40 0,000 0,03997594 0,04763232 ! activation of adenylate cyclase activity GO:0007190 42 41 0,000 0,04095595 0,04878376 ! positive regulation of binding GO:0051099 42 41 0,000 0,04095595 0,04876749 ! response to reactive oxygen species GO:0000302 43 41 0,000 0,04095595 0,04875124 ! solute:sodium symporter activity GO:0015370 41 41 0,000 0,04095595 0,04873499 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 44 41 0,000 0,04095595 0,04871876 GO:0046328|regulation of JNK cascade, ! mesenchymal cell development GO:0014031 43 41 0,000 0,04095595 0,04870253 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! heterocycle biosynthetic process GO:0018130 43 41 0,000 0,04095595 0,04868632 ! exonuclease activity GO:0004527 42 41 0,000 0,04095595 0,04867012 ! regulation of myeloid cell differentiation GO:0045637 43 41 0,000 0,04095595 0,04865393 ! positive regulation of cytokine production GO:0001819 42 41 0,000 0,04095595 0,04863775 ! hydro-lyase activity GO:0016836 44 41 0,000 0,04095595 0,04862158 ! positive regulation of protein transport GO:0051222 44 41 0,000 0,04095595 0,04860542 ! receptor-mediated endocytosis GO:0006898 43 41 0,000 0,04095595 0,04858927 ! regulation of neuron projection development GO:0010975 44 41 0,000 0,04095595 0,04857313 ! metal cluster binding GO:0051540 43 41 0,000 0,04095595 0,04855701 GO:0051536|iron-sulfur cluster binding, ! embryonic skeletal system morphogenesis GO:0048704 42 41 0,000 0,04095595 0,04854089 ! development of primary male sexual characteristics GO:0046546 41 41 0,000 0,04095595 0,04852479 ! double-strand break repair GO:0006302 41 41 0,000 0,04095595 0,04850869 ! Rab GTPase activator activity GO:0005097 42 41 0,000 0,04095595 0,04849261 ! RNA catabolic process GO:0006401 44 42 0,000 0,04193503 0,0496354 ! organellar ribosome GO:0000313 43 42 0,000 0,04193503 0,04961896 GO:0005761|mitochondrial ribosome, ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 44 42 0,000 0,04193503 0,04960252 ! damaged DNA binding GO:0003684 42 42 0,000 0,04193503 0,0495861 ! MHC protein complex GO:0042611 42 42 0,000 0,04193503 0,04956968 ! regulation of epithelial cell proliferation GO:0050678 44 42 0,000 0,04193503 0,04955328 ! negative regulation of cell migration GO:0030336 44 42 0,000 0,04193503 0,04953689 ! positive regulation of growth GO:0045927 42 42 0,000 0,04193503 0,04952051 ! icosanoid metabolic process GO:0006690 43 42 0,000 0,04193503 0,04950414 ! chemokine activity GO:0008009 42 42 0,000 0,04193503 0,04948778 ! ruffle GO:0001726 44 42 0,000 0,04193503 0,04947143 ! pigmentation GO:0043473 46 42 0,000 0,04193503 0,04945509 ! developmental growth GO:0048589 42 42 0,000 0,04193503 0,04943876 ! methylation GO:0032259 47 42 0,000 0,04193503 0,04942245 ! glycolysis GO:0006096 42 42 0,000 0,04193503 0,04940614 ! regulation of tube size GO:0035150 44 42 0,000 0,04193503 0,04938984 GO:0050880|regulation of blood vessel size, ! branching morphogenesis of a tube GO:0048754 43 42 0,000 0,04193503 0,04937356 ! general RNA polymerase II transcription factor activity GO:0016251 44 42 0,000 0,04193503 0,04935729 ! cellular amino acid derivative biosynthetic process GO:0042398 43 42 0,000 0,04193503 0,04934102 ! positive regulation of adenylate cyclase activity GO:0045762 44 43 0,000 0,04291318 0,05047529 ! transferase activity, transferring pentosyl groups GO:0016763 45 43 0,000 0,04291318 0,05045867 ! induction of apoptosis by intracellular signals GO:0008629 46 43 0,000 0,04291318 0,05044206 ! keratinocyte differentiation GO:0030216 46 43 0,000 0,04291318 0,05042546 ! epithelial cell differentiation GO:0030855 45 43 0,000 0,04291318 0,05040888 ! detection of stimulus involved in sensory perception GO:0050906 43 43 0,000 0,04291318 0,0503923 ! sulfotransferase activity GO:0008146 44 43 0,000 0,04291318 0,05037573 ! cellular polysaccharide metabolic process GO:0044264 44 43 0,000 0,04291318 0,05035918 ! channel regulator activity GO:0016247 46 43 0,000 0,04291318 0,05034264 ! histone modification GO:0016570 44 43 0,000 0,04291318 0,0503261 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 45 43 0,000 0,04291318 0,05030958 ! synaptosome GO:0019717 47 43 0,000 0,04291318 0,05029307 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 45 44 0,000 0,0438904 0,05142147 ! platelet alpha granule GO:0031091 46 44 0,000 0,0438904 0,0514046 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 44 44 0,000 0,0438904 0,05138775 ! regulation of ossification GO:0030278 48 44 0,000 0,0438904 0,0513709 ! cell recognition GO:0008037 46 44 0,000 0,0438904 0,05135407 ! positive regulation of cyclase activity GO:0031281 45 44 0,000 0,0438904 0,05133725 ! regulation of lymphocyte differentiation GO:0045619 48 44 0,000 0,0438904 0,05132044 ! regulation of actin filament polymerization GO:0030833 45 44 0,000 0,0438904 0,05130364 ! regulation of protein complex disassembly GO:0043244 46 44 0,000 0,0438904 0,05128685 ! regulation of ion transport GO:0043269 47 44 0,000 0,0438904 0,05127008 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 50 44 0,000 0,0438904 0,05125331 ! inner ear development GO:0048839 46 44 0,000 0,0438904 0,05123656 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 48 44 0,000 0,0438904 0,05121981 ! amino acid transmembrane transporter activity GO:0015171 44 44 0,000 0,0438904 0,05120308 ! negative regulation of immune system process GO:0002683 49 44 0,000 0,0438904 0,05118636 ! chemokine receptor binding GO:0042379 44 44 0,000 0,0438904 0,05116965 ! regulation of mast cell proliferation GO:0070666 48 44 0,000 0,0438904 0,05115295 ! regulation of action potential GO:0001508 50 45 0,000 0,04486669 0,05227372 ! regulation of gene-specific transcription GO:0032583 47 45 0,000 0,04486669 0,05225667 ! cellular amino acid biosynthetic process GO:0008652 47 45 0,000 0,04486669 0,05223963 ! nucleoside monophosphate biosynthetic process GO:0009124 50 45 0,000 0,04486669 0,0522226 ! positive regulation of lyase activity GO:0051349 46 45 0,000 0,04486669 0,05220559 ! regulation of neuron apoptosis GO:0043523 45 45 0,000 0,04486669 0,05218858 ! excretion GO:0007588 46 45 0,000 0,04486669 0,05217159 ! protein phosphatase regulator activity GO:0019888 49 45 0,000 0,04486669 0,0521546 ! JNK cascade GO:0007254 45 45 0,000 0,04486669 0,05213763 ! SH3/SH2 adaptor activity GO:0005070 48 45 0,000 0,04486669 0,05212067 ! regulation of cell shape GO:0008360 46 45 0,000 0,04486669 0,05210372 ! microbody part GO:0044438 46 45 0,000 0,04486669 0,05208678 GO:0044439|peroxisomal part, ! auxiliary transport protein activity GO:0015457 50 46 0,000 0,04584204 0,0532018 ! ATP synthesis coupled electron transport GO:0042773 46 46 0,000 0,04584204 0,05318452 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! microtubule binding GO:0008017 49 46 0,000 0,04584204 0,05316724 ! regulation of inflammatory response GO:0050727 46 46 0,000 0,04584204 0,05314998 ! transport vesicle GO:0030133 49 46 0,000 0,04584204 0,05313273 ! glutamine family amino acid metabolic process GO:0009064 49 46 0,000 0,04584204 0,05311549 ! synapse organization GO:0050808 51 46 0,000 0,04584204 0,05309826 ! G1/S transition of mitotic cell cycle GO:0000082 47 46 0,000 0,04584204 0,05308104 ! nuclear matrix GO:0016363 49 46 0,000 0,04584204 0,05306384 ! striated muscle contraction GO:0006941 49 46 0,000 0,04584204 0,05304664 ! unsaturated fatty acid metabolic process GO:0033559 47 46 0,000 0,04584204 0,05302946 ! antioxidant activity GO:0016209 47 46 0,000 0,04584204 0,05301229 ! aging GO:0007568 48 46 0,000 0,04584204 0,05299512 ! male sex differentiation GO:0046661 46 46 0,000 0,04584204 0,05297797 ! coated vesicle membrane GO:0030662 49 46 0,000 0,04584204 0,05296083 ! covalent chromatin modification GO:0016569 47 46 0,000 0,04584204 0,05294371 ! RNA elongation from RNA polymerase II promoter GO:0006368 48 46 0,000 0,04584204 0,05292659 ! regulation of leukocyte proliferation GO:0070663 50 46 0,000 0,04584204 0,05290948 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! protein amino acid lipidation GO:0006497 50 47 0,000 0,04681647 0,05401668 ! stress-activated protein kinase signaling pathway GO:0031098 47 47 0,000 0,04681647 0,05399923 ! carbohydrate transport GO:0008643 47 47 0,000 0,04681647 0,05398179 ! immunoglobulin mediated immune response GO:0016064 50 47 0,000 0,04681647 0,05396437 ! phosphatase regulator activity GO:0019208 51 47 0,000 0,04681647 0,05394696 ! vesicle organization GO:0016050 50 47 0,000 0,04681647 0,05392955 ! vascular process in circulatory system GO:0003018 49 47 0,000 0,04681647 0,05391216 ! cell cortex part GO:0044448 51 47 0,000 0,04681647 0,05389478 ! lipid modification GO:0030258 49 48 0,000 0,04778997 0,05499774 ! cytokine-mediated signaling pathway GO:0019221 49 48 0,000 0,04778997 0,05498002 ! morphogenesis of a branching structure GO:0001763 49 48 0,000 0,04778997 0,05496231 ! epidermal cell differentiation GO:0009913 51 48 0,000 0,04778997 0,05494461 ! mitochondrial transport GO:0006839 49 48 0,000 0,04778997 0,05492693 ! viral reproductive process GO:0022415 52 48 0,000 0,04778997 0,05490926 ! leukocyte migration GO:0050900 49 48 0,000 0,04778997 0,0548916 ! neuromuscular process GO:0050905 49 48 0,000 0,04778997 0,05487395 ! gastrulation GO:0007369 50 48 0,000 0,04778997 0,05485631 ! detection of abiotic stimulus GO:0009582 48 48 0,000 0,04778997 0,05483868 ! heterocycle catabolic process GO:0046700 53 48 0,000 0,04778997 0,05482106 ! B cell mediated immunity GO:0019724 51 48 0,000 0,04778997 0,05480346 ! protein N-terminus binding GO:0047485 51 48 0,000 0,04778997 0,05478587 ! transferase activity, transferring sulfur-containing groups GO:0016782 50 49 0,000 0,04876254 0,05588287 ! single-stranded DNA binding GO:0003697 49 49 0,000 0,04876254 0,05586494 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 54 49 0,000 0,04876254 0,05584702 ! intrinsic to endoplasmic reticulum membrane GO:0031227 50 49 0,000 0,04876254 0,05582912 ! ribonuclease activity GO:0004540 50 49 0,000 0,04876254 0,05581122 ! positive regulation of organelle organization GO:0010638 49 49 0,000 0,04876254 0,05579334 ! water-soluble vitamin metabolic process GO:0006767 50 49 0,000 0,04876254 0,05577547 ! lamellipodium GO:0030027 53 49 0,000 0,04876254 0,05575761 ! negative regulation of cell motion GO:0051271 51 49 0,000 0,04876254 0,05573976 ! nucleosome GO:0000786 49 49 0,000 0,04876254 0,05572193 ! kinetochore GO:0000776 50 49 0,000 0,04876254 0,0557041 ! membrane fusion GO:0006944 51 49 0,000 0,04876254 0,05568629 ! endocrine system development GO:0035270 49 49 0,000 0,04876254 0,05566848 ! RNA elongation GO:0006354 51 49 0,000 0,04876254 0,05565069 ! response to UV GO:0009411 50 49 0,000 0,04876254 0,05563291 ! glycosaminoglycan metabolic process GO:0030203 53 50 0,000 0,04973418 0,05672333 ! regulation of actin polymerization or depolymerization GO:0008064 51 50 0,000 0,04973418 0,05670522 ! basement membrane GO:0005604 51 50 0,000 0,04973418 0,05668712 ! regulation of intracellular transport GO:0032386 52 50 0,000 0,04973418 0,05666903 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,04973418 0,05665096 ! maintenance of location GO:0051235 51 50 0,000 0,04973418 0,05663289 ! nuclear periphery GO:0034399 53 50 0,000 0,04973418 0,05661484 ! regulation of cyclin-dependent protein kinase activity GO:0000079 51 50 0,000 0,04973418 0,0565968 ! cell redox homeostasis GO:0045454 51 50 0,000 0,04973418 0,05657877 ! integrin binding GO:0005178 53 50 0,000 0,04973418 0,05656075 ! regulation of DNA replication GO:0006275 56 50 0,000 0,04973418 0,05654274 ! amino acid activation GO:0043038 50 50 0,000 0,04973418 0,05652475 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! establishment of organelle localization GO:0051656 53 50 0,000 0,04973418 0,05650676 ! regulation of bone remodeling GO:0046850 55 51 0,000 0,05070489 0,05759134 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 52 51 0,000 0,05070489 0,05757303 ! late endosome GO:0005770 51 51 0,000 0,05070489 0,05755473 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 56 51 0,000 0,05070489 0,05753644 ! ligase activity, forming carbon-oxygen bonds GO:0016875 51 51 0,000 0,05070489 0,05751816 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! negative regulation of response to stimulus GO:0048585 55 51 0,000 0,05070489 0,0574999 ! carbon-oxygen lyase activity GO:0016835 54 51 0,000 0,05070489 0,05748164 ! skeletal muscle fiber development GO:0048741 54 51 0,000 0,05070489 0,0574634 ! lipoprotein biosynthetic process GO:0042158 54 51 0,000 0,05070489 0,05744517 ! heart morphogenesis GO:0003007 54 51 0,000 0,05070489 0,05742695 ! steroid hormone receptor activity GO:0003707 53 51 0,000 0,05070489 0,05740874 ! antiporter activity GO:0015297 52 51 0,000 0,05070489 0,05739055 ! respiratory electron transport chain GO:0022904 52 52 0,000 0,05167468 0,05846968 ! positive regulation of cell migration GO:0030335 55 52 0,000 0,05167468 0,05845115 ! Golgi-associated vesicle GO:0005798 55 52 0,000 0,05167468 0,05843265 ! sphingolipid metabolic process GO:0006665 53 52 0,000 0,05167468 0,05841415 ! cell maturation GO:0048469 55 52 0,000 0,05167468 0,05839566 ! regulation of protein polymerization GO:0032271 53 52 0,000 0,05167468 0,05837719 ! regulation of actin filament length GO:0030832 53 52 0,000 0,05167468 0,05835873 ! regulation of cell projection organization GO:0031344 55 52 0,000 0,05167468 0,05834028 ! chloride transport GO:0006821 53 52 0,000 0,05167468 0,05832184 ! positive regulation of protein amino acid phosphorylation GO:0001934 54 52 0,000 0,05167468 0,05830341 ! muscle fiber development GO:0048747 55 52 0,000 0,05167468 0,058285 ! regulation of muscle contraction GO:0006937 56 52 0,000 0,05167468 0,05826659 ! negative regulation of cytoskeleton organization GO:0051494 57 52 0,000 0,05167468 0,0582482 ! glucose catabolic process GO:0006007 52 52 0,000 0,05167468 0,05822982 ! generation of a signal involved in cell-cell signaling GO:0003001 54 52 0,000 0,05167468 0,05821145 ! small ribosomal subunit GO:0015935 52 52 0,000 0,05167468 0,05819309 ! cytokine receptor activity GO:0004896 53 52 0,000 0,05167468 0,05817475 ! activation of phospholipase C activity GO:0007202 55 53 0,000 0,05264355 0,05924681 GO:0010863|positive regulation of phospholipase C activity, ! nucleoside monophosphate metabolic process GO:0009123 58 53 0,000 0,05264355 0,05922814 ! nucleoside metabolic process GO:0009116 61 53 0,000 0,05264355 0,05920948 ! N-acetyltransferase activity GO:0008080 54 53 0,000 0,05264355 0,05919084 ! synaptic vesicle GO:0008021 57 53 0,000 0,05264355 0,05917221 ! pyridoxal phosphate binding GO:0030170 56 53 0,000 0,05264355 0,05915359 GO:0070279|vitamin B6 binding, ! viral reproduction GO:0016032 57 53 0,000 0,05264355 0,05913498 ! cell projection assembly GO:0030031 56 53 0,000 0,05264355 0,05911639 ! embryonic skeletal system development GO:0048706 54 53 0,000 0,05264355 0,0590978 ! proton transport GO:0015992 53 53 0,000 0,05264355 0,05907923 ! mRNA binding GO:0003729 55 53 0,000 0,05264355 0,05906067 ! single fertilization GO:0007338 55 53 0,000 0,05264355 0,05904212 ! axon GO:0030424 58 54 0,000 0,05361149 0,06010883 ! heat shock protein binding GO:0031072 54 54 0,000 0,05361149 0,06008997 ! regulation of neurotransmitter levels GO:0001505 60 54 0,000 0,05361149 0,06007111 ! double-stranded DNA binding GO:0003690 55 54 0,000 0,05361149 0,06005227 ! positive regulation of phospholipase activity GO:0010518 56 54 0,000 0,05361149 0,06003344 ! tRNA processing GO:0008033 55 54 0,000 0,05361149 0,06001462 ! regulation of cellular response to stress GO:0080135 57 54 0,000 0,05361149 0,05999581 ! growth factor receptor binding GO:0070851 56 54 0,000 0,05361149 0,05997702 ! regulation of tissue remodeling GO:0034103 58 54 0,000 0,05361149 0,05995823 ! regulation of cellular component size GO:0032535 56 55 0,000 0,05457851 0,06102062 ! response to peptide hormone stimulus GO:0043434 60 55 0,000 0,05457851 0,06100152 ! hydrogen transport GO:0006818 55 55 0,000 0,05457851 0,06098243 ! glycerophospholipid biosynthetic process GO:0046474 59 55 0,000 0,05457851 0,06096336 ! nucleotide-excision repair GO:0006289 58 55 0,000 0,05457851 0,06094429 ! large ribosomal subunit GO:0015934 56 55 0,000 0,05457851 0,06092524 ! protein amino acid autophosphorylation GO:0046777 57 55 0,000 0,05457851 0,0609062 ! positive regulation of secretion GO:0051047 60 56 0,000 0,0555446 0,06196494 ! regulation of mitosis GO:0007088 56 56 0,000 0,0555446 0,06194559 GO:0051783|regulation of nuclear division, ! actin filament organization GO:0007015 59 56 0,000 0,0555446 0,06192625 ! regulation of phospholipase activity GO:0010517 58 56 0,000 0,0555446 0,06190692 ! coenzyme biosynthetic process GO:0009108 59 56 0,000 0,0555446 0,06188761 ! cellular amino acid catabolic process GO:0009063 59 56 0,000 0,0555446 0,0618683 ! cartilage development GO:0051216 59 56 0,000 0,0555446 0,06184901 ! regulation of protein complex assembly GO:0043254 57 56 0,000 0,0555446 0,06182973 ! receptor signaling protein serine/threonine kinase activity GO:0004702 58 56 0,000 0,0555446 0,06181047 ! mesoderm development GO:0007498 57 56 0,000 0,0555446 0,06179121 ! camera-type eye development GO:0043010 59 56 0,000 0,0555446 0,06177197 ! regulation of transcription factor activity GO:0051090 59 57 0,000 0,05650978 0,06282578 GO:0090046|regulation of transcription regulator activity, ! ear development GO:0043583 60 57 0,000 0,05650978 0,06280623 ! chromosome segregation GO:0007059 59 57 0,000 0,05650978 0,06278669 ! positive regulation of T cell activation GO:0050870 62 57 0,000 0,05650978 0,06276716 ! kidney development GO:0001822 60 57 0,000 0,05650978 0,06274764 ! positive regulation of lipase activity GO:0060193 59 57 0,000 0,05650978 0,06272814 ! positive regulation of phosphorylation GO:0042327 59 57 0,000 0,05650978 0,06270865 ! integrin-mediated signaling pathway GO:0007229 61 57 0,000 0,05650978 0,06268916 ! adult behavior GO:0030534 60 57 0,000 0,05650978 0,0626697 ! steroid hormone receptor signaling pathway GO:0030518 58 57 0,000 0,05650978 0,06265024 ! myosin complex GO:0016459 59 57 0,000 0,05650978 0,06263079 ! regulation of angiogenesis GO:0045765 60 58 0,000 0,05747403 0,06367973 ! lysosomal membrane GO:0005765 59 58 0,000 0,05747403 0,06365998 ! positive regulation of phosphorus metabolic process GO:0010562 61 58 0,000 0,05747403 0,06364024 GO:0045937|positive regulation of phosphate metabolic process, ! extracellular matrix organization GO:0030198 59 58 0,000 0,05747403 0,06362051 ! positive regulation of cell motion GO:0051272 61 58 0,000 0,05747403 0,0636008 ! homeostasis of number of cells GO:0048872 62 58 0,000 0,05747403 0,06358109 ! regulation of vesicle-mediated transport GO:0060627 60 58 0,000 0,05747403 0,0635614 ! detection of external stimulus GO:0009581 59 58 0,000 0,05747403 0,06354172 ! secondary metabolic process GO:0019748 59 58 0,000 0,05747403 0,06352206 ! translation initiation factor activity GO:0003743 58 58 0,000 0,05747403 0,0635024 ! dendrite GO:0030425 61 59 0,000 0,05843737 0,06454681 ! molecular adaptor activity GO:0060090 65 59 0,000 0,05843737 0,06452685 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 60 59 0,000 0,05843737 0,0645069 GO:0051213|dioxygenase activity, ! embryonic limb morphogenesis GO:0030326 63 59 0,000 0,05843737 0,06448697 GO:0035113|embryonic appendage morphogenesis, ! ubiquitin thiolesterase activity GO:0004221 62 59 0,000 0,05843737 0,06446705 ! regulation of heart contraction GO:0008016 62 59 0,000 0,05843737 0,06444714 ! copper ion binding GO:0005507 61 59 0,000 0,05843737 0,06442724 ! activation of immune response GO:0002253 68 59 0,000 0,05843737 0,06440736 ! aminoglycan metabolic process GO:0006022 62 59 0,000 0,05843737 0,06438748 ! amine transmembrane transporter activity GO:0005275 59 59 0,000 0,05843737 0,06436762 ! chromatin remodeling complex GO:0016585 61 59 0,000 0,05843737 0,06434778 ! cell soma GO:0043025 63 59 0,000 0,05843737 0,06432794 ! regulation of homeostatic process GO:0032844 68 59 0,000 0,05843737 0,06430812 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 61 60 0,000 0,05939978 0,06534708 ! multicellular organism reproduction GO:0032504 62 60 0,000 0,05939978 0,06532695 GO:0048609|reproductive process in a multicellular organism, ! occluding junction GO:0070160 60 60 0,000 0,05939978 0,06530684 GO:0005923|tight junction, ! regulation of lipid metabolic process GO:0019216 63 60 0,000 0,05939978 0,06528674 ! myeloid cell differentiation GO:0030099 64 60 0,000 0,05939978 0,06526665 ! oxygen and reactive oxygen species metabolic process GO:0006800 60 60 0,000 0,05939978 0,06524658 ! regulation of cytokine biosynthetic process GO:0042035 63 60 0,000 0,05939978 0,06522651 ! lymphocyte mediated immunity GO:0002449 63 60 0,000 0,05939978 0,06520646 ! chloride channel activity GO:0005254 61 60 0,000 0,05939978 0,06518642 ! negative regulation of protein kinase activity GO:0006469 67 61 0,000 0,06036128 0,06622124 ! fertilization GO:0009566 64 61 0,000 0,06036128 0,0662009 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 65 61 0,000 0,06036128 0,06618057 ! gonad development GO:0008406 61 61 0,000 0,06036128 0,06616026 ! protein maturation by peptide bond cleavage GO:0051605 64 61 0,000 0,06036128 0,06613996 ! regulation of immune effector process GO:0002697 65 61 0,000 0,06036128 0,06611967 ! amine catabolic process GO:0009310 68 62 0,000 0,06132186 0,06715129 ! phosphoinositide metabolic process GO:0030384 66 62 0,000 0,06132186 0,0671307 ! glycerolipid biosynthetic process GO:0045017 66 62 0,000 0,06132186 0,06711013 ! coated membrane GO:0048475 67 62 0,000 0,06132186 0,06708957 GO:0030117|membrane coat, ! hexose catabolic process GO:0019320 63 62 0,000 0,06132186 0,06706902 ! negative regulation of kinase activity GO:0033673 68 62 0,000 0,06132186 0,06704849 ! extracellular ligand-gated ion channel activity GO:0005230 67 62 0,000 0,06132186 0,06702796 ! germ cell development GO:0007281 62 62 0,000 0,06132186 0,06700745 ! ligand-dependent nuclear receptor activity GO:0004879 65 62 0,000 0,06132186 0,06698695 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 70 63 0,000 0,06228152 0,06801447 ! protein oligomerization GO:0051259 64 63 0,000 0,06228152 0,06799367 ! transition metal ion transport GO:0000041 65 63 0,000 0,06228152 0,06797289 ! appendage morphogenesis GO:0035107 67 63 0,000 0,06228152 0,06795213 GO:0035108|limb morphogenesis, ! activation of MAPK activity GO:0000187 69 63 0,000 0,06228152 0,06793137 ! cellular defense response GO:0006968 64 63 0,000 0,06228152 0,06791063 ! B cell activation GO:0042113 66 63 0,000 0,06228152 0,0678899 ! antigen processing and presentation GO:0019882 64 63 0,000 0,06228152 0,06786918 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 65 63 0,000 0,06228152 0,06784848 ! microtubule motor activity GO:0003777 67 63 0,000 0,06228152 0,06782779 ! intracellular receptor-mediated signaling pathway GO:0030522 64 63 0,000 0,06228152 0,06780711 ! organelle localization GO:0051640 66 63 0,000 0,06228152 0,06778644 ! transforming growth factor beta receptor signaling pathway GO:0007179 67 64 0,000 0,06324027 0,06880896 ! lung development GO:0030324 65 64 0,000 0,06324027 0,068788 ! developmental maturation GO:0021700 67 64 0,000 0,06324027 0,06876705 ! amino acid transport GO:0006865 64 64 0,000 0,06324027 0,06874612 ! protein kinase regulator activity GO:0019887 64 64 0,000 0,06324027 0,0687252 ! anion channel activity GO:0005253 65 64 0,000 0,06324027 0,06870429 ! cellular hormone metabolic process GO:0034754 65 65 0,000 0,0641981 0,06972367 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 65 0,000 0,0641981 0,06970247 ! negative regulation of cell growth GO:0030308 68 65 0,000 0,0641981 0,06968128 ! nuclear pore GO:0005643 69 65 0,000 0,0641981 0,06966011 ! regulation of MAPKKK cascade GO:0043408 72 65 0,000 0,0641981 0,06963895 ! negative regulation of transferase activity GO:0051348 71 65 0,000 0,0641981 0,0696178 ! rhythmic process GO:0048511 66 65 0,000 0,0641981 0,06959666 ! regulation of lipase activity GO:0060191 67 65 0,000 0,0641981 0,06957554 ! adaptive immune response GO:0002250 68 65 0,000 0,0641981 0,06955443 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! response to metal ion GO:0010038 69 65 0,000 0,0641981 0,06953334 ! positive regulation of protein modification process GO:0031401 69 65 0,000 0,0641981 0,06951225 ! appendage development GO:0048736 69 65 0,000 0,0641981 0,06949118 GO:0060173|limb development, ! skeletal system morphogenesis GO:0048705 66 65 0,000 0,0641981 0,06947013 ! lipoprotein metabolic process GO:0042157 68 65 0,000 0,0641981 0,06944908 ! DNA-dependent DNA replication GO:0006261 66 65 0,000 0,0641981 0,06942805 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 71 66 0,000 0,06515502 0,07044159 ! endoplasmic reticulum lumen GO:0005788 66 66 0,000 0,06515502 0,07042027 ! urogenital system development GO:0001655 69 66 0,000 0,06515502 0,07039896 ! response to steroid hormone stimulus GO:0048545 69 66 0,000 0,06515502 0,07037767 ! diacylglycerol binding GO:0019992 71 66 0,000 0,06515502 0,07035639 ! amine binding GO:0043176 70 66 0,000 0,06515502 0,07033512 ! response to nutrient GO:0007584 67 66 0,000 0,06515502 0,07031386 ! acetyltransferase activity GO:0016407 68 66 0,000 0,06515502 0,07029262 ! negative regulation of cell size GO:0045792 70 67 0,000 0,06611102 0,07130246 ! respiratory tube development GO:0030323 68 67 0,000 0,06611102 0,07128094 ! mRNA transport GO:0051028 70 67 0,000 0,06611102 0,07125942 ! intracellular protein transmembrane transport GO:0065002 70 67 0,000 0,06611102 0,07123792 ! tubulin binding GO:0015631 70 67 0,000 0,06611102 0,07121643 ! positive regulation of lymphocyte activation GO:0051251 72 67 0,000 0,06611102 0,07119495 ! activation of protein kinase activity GO:0032147 70 67 0,000 0,06611102 0,07117349 ! Ras GTPase binding GO:0017016 70 67 0,000 0,06611102 0,07115204 ! humoral immune response GO:0006959 70 67 0,000 0,06611102 0,0711306 ! nuclear hormone receptor binding GO:0035257 68 67 0,000 0,06611102 0,07110917 ! ubiquitin ligase complex GO:0000151 71 67 0,000 0,06611102 0,07108776 ! nucleosome assembly GO:0006334 69 67 0,000 0,06611102 0,07106636 ! transcription initiation from RNA polymerase II promoter GO:0006367 71 67 0,000 0,06611102 0,07104498 ! muscle cell differentiation GO:0042692 68 68 0,000 0,06706611 0,07204967 ! fatty acid biosynthetic process GO:0006633 70 68 0,000 0,06706611 0,072028 ! protein import into nucleus GO:0006606 72 68 0,000 0,06706611 0,07200634 ! lymphocyte differentiation GO:0030098 75 68 0,000 0,06706611 0,0719847 ! regulation of actin cytoskeleton organization GO:0032956 74 68 0,000 0,06706611 0,07196307 ! protein-DNA complex GO:0032993 69 68 0,000 0,06706611 0,07194145 ! learning or memory GO:0007611 72 68 0,000 0,06706611 0,07191985 ! chloride ion binding GO:0031404 70 68 0,000 0,06706611 0,07189826 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 71 68 0,000 0,06706611 0,07187668 ! chromatin assembly GO:0031497 70 68 0,000 0,06706611 0,07185511 ! leukocyte mediated immunity GO:0002443 71 68 0,000 0,06706611 0,07183356 ! extrinsic to membrane GO:0019898 68 68 0,000 0,06706611 0,07181202 ! calcium channel activity GO:0005262 73 68 0,000 0,06706611 0,0717905 ! ribonucleoprotein complex assembly GO:0022618 69 68 0,000 0,06706611 0,07176898 ! respiratory system development GO:0060541 69 68 0,000 0,06706611 0,07174748 ! N-acyltransferase activity GO:0016410 69 68 0,000 0,06706611 0,07172599 ! eye development GO:0001654 74 69 0,000 0,06802029 0,07272469 ! sarcomere GO:0030017 75 69 0,000 0,06802029 0,07270292 ! cAMP-mediated signaling GO:0019933 72 69 0,000 0,06802029 0,07268117 ! axon guidance GO:0007411 74 69 0,000 0,06802029 0,07265943 ! focal adhesion GO:0005925 75 69 0,000 0,06802029 0,0726377 ! regulation of DNA binding GO:0051101 72 70 0,000 0,06897356 0,07363366 ! carboxylic acid transmembrane transporter activity GO:0046943 71 70 0,000 0,06897356 0,07361165 ! early endosome GO:0005769 79 70 0,000 0,06897356 0,07358966 ! response to hypoxia GO:0001666 76 70 0,000 0,06897356 0,07356768 ! nuclear import GO:0051170 74 70 0,000 0,06897356 0,07354571 ! response to inorganic substance GO:0010035 74 70 0,000 0,06897356 0,07352376 ! female pregnancy GO:0007565 71 70 0,000 0,06897356 0,07350182 ! rRNA processing GO:0006364 70 70 0,000 0,06897356 0,07347989 ! cytosolic ribosome GO:0022626 70 70 0,000 0,06897356 0,07345798 ! cell cortex GO:0005938 74 70 0,000 0,06897356 0,07343608 ! FAD binding GO:0050660 72 71 0,000 0,06992592 0,07442786 ! response to oxygen levels GO:0070482 77 71 0,000 0,06992592 0,07440568 ! mitochondrial outer membrane GO:0005741 75 71 0,000 0,06992592 0,07438352 ! defense response to bacterium GO:0042742 71 71 0,000 0,06992592 0,07436137 ! steroid biosynthetic process GO:0006694 72 71 0,000 0,06992592 0,07433923 ! monosaccharide catabolic process GO:0046365 72 71 0,000 0,06992592 0,0743171 ! regulation of synaptic transmission GO:0050804 73 71 0,000 0,06992592 0,07429499 ! reproductive structure development GO:0048608 71 71 0,000 0,06992592 0,07427289 ! neurotransmitter transport GO:0006836 73 71 0,000 0,06992592 0,07425081 ! regulation of actin filament-based process GO:0032970 77 71 0,000 0,06992592 0,07422874 ! organic acid transmembrane transporter activity GO:0005342 72 71 0,000 0,06992592 0,07420668 ! phospholipase activity GO:0004620 75 71 0,000 0,06992592 0,07418463 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 75 71 0,000 0,06992592 0,0741626 ! cell projection part GO:0044463 75 71 0,000 0,06992592 0,07414058 ! amine biosynthetic process GO:0009309 75 72 0,000 0,07087737 0,07512707 ! meiosis GO:0007126 73 72 0,000 0,07087737 0,07510478 GO:0051327|M phase of meiotic cell cycle, ! elevation of cytosolic calcium ion concentration GO:0007204 77 72 0,000 0,07087737 0,0750825 ! acute inflammatory response GO:0002526 76 72 0,000 0,07087737 0,07506023 ! cholesterol metabolic process GO:0008203 74 72 0,000 0,07087737 0,07503798 ! lipid transporter activity GO:0005319 77 72 0,000 0,07087737 0,07501574 ! cell-substrate adherens junction GO:0005924 78 72 0,000 0,07087737 0,07499351 ! negative regulation of transport GO:0051051 74 73 0,000 0,07182791 0,07597674 ! vacuolar membrane GO:0005774 74 73 0,000 0,07182791 0,07595424 ! rRNA metabolic process GO:0016072 73 73 0,000 0,07182791 0,07593176 ! meiotic cell cycle GO:0051321 75 73 0,000 0,07182791 0,07590929 ! negative regulation of organelle organization GO:0010639 78 73 0,000 0,07182791 0,07588683 ! regulation of protein transport GO:0051223 77 73 0,000 0,07182791 0,07586438 GO:0070201|regulation of establishment of protein localization, ! cytosolic calcium ion homeostasis GO:0051480 78 73 0,000 0,07182791 0,07584195 ! hormone receptor binding GO:0051427 75 73 0,000 0,07182791 0,07581953 ! nucleosome organization GO:0034728 76 74 0,000 0,07277755 0,07679924 ! neuropeptide signaling pathway GO:0007218 79 74 0,000 0,07277755 0,07677655 ! pore complex GO:0046930 78 74 0,000 0,07277755 0,07675388 ! protein localization in nucleus GO:0034504 78 74 0,000 0,07277755 0,07673122 ! myofibril GO:0030016 80 74 0,000 0,07277755 0,07670857 ! regulation of blood pressure GO:0008217 76 74 0,000 0,07277755 0,07668593 ! apical junction complex GO:0043296 74 74 0,000 0,07277755 0,07666331 ! cellular carbohydrate catabolic process GO:0044275 75 74 0,000 0,07277755 0,0766407 ! development of primary sexual characteristics GO:0045137 74 74 0,000 0,07277755 0,07661811 ! membrane raft GO:0045121 78 74 0,000 0,07277755 0,07659553 ! regulation of Rho protein signal transduction GO:0035023 79 74 0,000 0,07277755 0,07657296 ! cellular response to hormone stimulus GO:0032870 81 74 0,000 0,07277755 0,07655041 ! serine-type endopeptidase inhibitor activity GO:0004867 75 74 0,000 0,07277755 0,07652786 ! nuclear chromosome part GO:0044454 76 74 0,000 0,07277755 0,07650534 ! response to drug GO:0042493 77 75 0,000 0,07372628 0,07747985 ! small GTPase binding GO:0031267 78 75 0,000 0,07372628 0,07745705 ! cell-substrate junction GO:0030055 82 75 0,000 0,07372628 0,07743427 ! establishment of RNA localization GO:0051236 78 75 0,000 0,07372628 0,07741151 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! positive regulation of cell activation GO:0050867 80 75 0,000 0,07372628 0,07738875 GO:0002696|positive regulation of leukocyte activation, ! membrane lipid biosynthetic process GO:0046467 77 75 0,000 0,07372628 0,07736601 ! phosphoinositide-mediated signaling GO:0048015 79 75 0,000 0,07372628 0,07734328 ! cellular lipid catabolic process GO:0044242 77 75 0,000 0,07372628 0,07732057 ! cysteine-type endopeptidase activity GO:0004197 75 75 0,000 0,07372628 0,07729787 ! structural constituent of cytoskeleton GO:0005200 81 75 0,000 0,07372628 0,07727518 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 80 76 0,000 0,0746741 0,07824566 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 76 76 0,000 0,0746741 0,0782227 ! vitamin metabolic process GO:0006766 77 76 0,000 0,0746741 0,07819976 ! chromosome, centromeric region GO:0000775 78 76 0,000 0,0746741 0,07817684 ! apicolateral plasma membrane GO:0016327 76 76 0,000 0,0746741 0,07815393 ! T cell activation GO:0042110 82 76 0,000 0,0746741 0,07813103 ! digestion GO:0007586 80 76 0,000 0,0746741 0,07810814 ! cilium GO:0005929 77 76 0,000 0,0746741 0,07808527 ! contractile fiber part GO:0044449 82 76 0,000 0,0746741 0,07806241 ! regulation of adenylate cyclase activity GO:0045761 80 77 0,000 0,07562101 0,07902916 ! RNA localization GO:0006403 80 77 0,000 0,07562101 0,07900604 ! nuclear speck GO:0016607 80 77 0,000 0,07562101 0,07898293 ! G-protein-coupled receptor binding GO:0001664 78 77 0,000 0,07562101 0,07895983 ! endonuclease activity GO:0004519 80 77 0,000 0,07562101 0,07893675 ! regulation of transmission of nerve impulse GO:0051969 79 77 0,000 0,07562101 0,07891369 ! hydrogen ion transmembrane transporter activity GO:0015078 78 77 0,000 0,07562101 0,07889063 ! kinase regulator activity GO:0019207 77 77 0,000 0,07562101 0,07886759 ! extracellular matrix structural constituent GO:0005201 80 77 0,000 0,07562101 0,07884456 ! vacuolar part GO:0044437 78 77 0,000 0,07562101 0,07882155 ! thiolester hydrolase activity GO:0016790 81 78 0,000 0,07656702 0,07978431 ! potassium channel complex GO:0034705 81 78 0,000 0,07656702 0,07976104 GO:0008076|voltage-gated potassium channel complex, ! regulation of cell adhesion GO:0030155 82 78 0,000 0,07656702 0,07973778 ! cofactor biosynthetic process GO:0051188 81 78 0,000 0,07656702 0,07971453 ! blood coagulation GO:0007596 81 78 0,000 0,07656702 0,0796913 GO:0050817|coagulation, ! phospholipid biosynthetic process GO:0008654 83 79 0,000 0,07751213 0,08065146 ! biogenic amine metabolic process GO:0006576 85 79 0,000 0,07751213 0,08062797 ! phosphoric diester hydrolase activity GO:0008081 82 79 0,000 0,07751213 0,08060449 ! positive regulation of MAP kinase activity GO:0043406 85 79 0,000 0,07751213 0,08058102 ! regulation of cyclase activity GO:0031279 82 79 0,000 0,07751213 0,08055757 ! regulation of neuron differentiation GO:0045664 82 79 0,000 0,07751213 0,08053413 ! regulation of T cell activation GO:0050863 84 79 0,000 0,07751213 0,08051071 ! regulation of cAMP biosynthetic process GO:0030817 82 79 0,000 0,07751213 0,0804873 ! exocytosis GO:0006887 81 79 0,000 0,07751213 0,0804639 ! nitrogen compound catabolic process GO:0044270 89 79 0,000 0,07751213 0,08044052 ! regulation of protein localization GO:0032880 83 79 0,000 0,07751213 0,08041715 ! regulation of DNA metabolic process GO:0051052 90 80 0,000 0,07845633 0,0813731 ! alcohol catabolic process GO:0046164 83 80 0,000 0,07845633 0,08134947 ! GTPase binding GO:0051020 83 80 0,000 0,07845633 0,08132586 ! regulation of cell cycle process GO:0010564 84 80 0,000 0,07845633 0,08130226 ! negative regulation of growth GO:0045926 84 80 0,000 0,07845633 0,08127867 ! regulation of Ras GTPase activity GO:0032318 84 80 0,000 0,07845633 0,0812551 ! regulation of lyase activity GO:0051339 83 80 0,000 0,07845633 0,08123154 ! ATP biosynthetic process GO:0006754 85 80 0,000 0,07845633 0,08120799 ! one-carbon metabolic process GO:0006730 87 80 0,000 0,07845633 0,08118446 ! monooxygenase activity GO:0004497 82 80 0,000 0,07845633 0,08116094 ! condensed chromosome GO:0000793 82 80 0,000 0,07845633 0,08113744 ! contractile fiber GO:0043292 86 80 0,000 0,07845633 0,08111395 ! protein kinase binding GO:0019901 89 80 0,000 0,07845633 0,08109047 ! protein ubiquitination GO:0016567 86 80 0,000 0,07845633 0,08106701 ! ossification GO:0001503 85 81 0,000 0,07939964 0,08201797 ! cellular carbohydrate biosynthetic process GO:0034637 83 81 0,000 0,07939964 0,08199425 ! sterol metabolic process GO:0016125 83 81 0,000 0,07939964 0,08197054 ! regulation of cAMP metabolic process GO:0030814 84 81 0,000 0,07939964 0,08194685 ! protein binding, bridging GO:0030674 86 81 0,000 0,07939964 0,08192317 ! regulation of neurological system process GO:0031644 83 81 0,000 0,07939964 0,08189951 ! protein transporter activity GO:0008565 85 82 0,000 0,08034204 0,08284765 ! positive regulation of immune response GO:0050778 91 82 0,000 0,08034204 0,08282374 ! interphase of mitotic cell cycle GO:0051329 84 82 0,000 0,08034204 0,08279983 GO:0051325|interphase, ! regulation of defense response GO:0031347 82 82 0,000 0,08034204 0,08277594 ! bone development GO:0060348 86 82 0,000 0,08034204 0,08275207 ! carboxylesterase activity GO:0004091 86 82 0,000 0,08034204 0,08272821 ! transcription initiation GO:0006352 86 82 0,000 0,08034204 0,08270436 ! mitochondrion organization GO:0007005 86 83 0,000 0,08128354 0,08364943 ! organelle outer membrane GO:0031968 87 83 0,000 0,08128354 0,08362533 ! cell leading edge GO:0031252 90 83 0,000 0,08128354 0,08360124 ! SH3 domain binding GO:0017124 97 83 0,000 0,08128354 0,08357717 ! hemostasis GO:0007599 86 83 0,000 0,08128354 0,08355311 ! oxidative phosphorylation GO:0006119 83 83 0,000 0,08128354 0,08352907 ! heparin binding GO:0008201 90 83 0,000 0,08128354 0,08350504 ! amine transport GO:0015837 83 83 0,000 0,08128354 0,08348102 ! extracellular matrix part GO:0044420 85 83 0,000 0,08128354 0,08345702 ! phosphoinositide binding GO:0035091 90 83 0,000 0,08128354 0,08343303 ! regulation of nucleotide biosynthetic process GO:0030808 87 84 0,000 0,08222414 0,08437425 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! Ras GTPase activator activity GO:0005099 89 84 0,000 0,08222414 0,08435002 ! regulation of membrane potential GO:0042391 92 84 0,000 0,08222414 0,08432579 ! perinuclear region of cytoplasm GO:0048471 91 85 0,000 0,08316384 0,08526503 ! transmembrane receptor protein kinase activity GO:0019199 88 85 0,000 0,08316384 0,08524055 ! outer membrane GO:0019867 89 85 0,000 0,08316384 0,08521609 ! DNA recombination GO:0006310 86 85 0,000 0,08316384 0,08519165 ! neurotransmitter receptor activity GO:0030594 86 85 0,000 0,08316384 0,08516722 ! leukocyte differentiation GO:0002521 95 86 0,000 0,08410265 0,08610394 ! Golgi vesicle transport GO:0048193 86 86 0,000 0,08410265 0,08607926 ! pigment granule GO:0048770 90 86 0,000 0,08410265 0,0860546 GO:0042470|melanosome, ! neurotransmitter binding GO:0042165 88 86 0,000 0,08410265 0,08602995 ! anion binding GO:0043168 89 86 0,000 0,08410265 0,08600531 ! sex differentiation GO:0007548 86 86 0,000 0,08410265 0,08598069 ! UDP-glycosyltransferase activity GO:0008194 91 86 0,000 0,08410265 0,08595608 ! microtubule cytoskeleton organization GO:0000226 92 87 0,000 0,08504055 0,08688979 ! cell cycle arrest GO:0007050 92 87 0,000 0,08504055 0,08686494 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 93 87 0,000 0,08504055 0,0868401 ! regulation of cyclic nucleotide metabolic process GO:0030799 90 87 0,000 0,08504055 0,08681527 ! protein processing GO:0016485 92 87 0,000 0,08504055 0,08679046 ! ATP-dependent helicase activity GO:0008026 92 88 0,000 0,08597756 0,08772168 GO:0070035|purine NTP-dependent helicase activity, ! monovalent inorganic cation transmembrane transporter activity GO:0015077 89 88 0,000 0,08597756 0,08769662 ! skeletal muscle tissue development GO:0007519 92 88 0,000 0,08597756 0,08767158 GO:0060538|skeletal muscle organ development, ! lipase activity GO:0016298 92 88 0,000 0,08597756 0,08764655 ! detection of stimulus GO:0051606 90 88 0,000 0,08597756 0,08762154 ! carboxylic acid catabolic process GO:0046395 93 89 0,000 0,08691368 0,08855028 GO:0016054|organic acid catabolic process, ! sulfur metabolic process GO:0006790 90 89 0,000 0,08691368 0,08852503 ! negative regulation of multicellular organismal process GO:0051241 93 89 0,000 0,08691368 0,08849979 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 92 89 0,000 0,08691368 0,08847456 ! regulation of binding GO:0051098 93 90 0,000 0,0878489 0,08940109 ! intermediate filament GO:0005882 92 90 0,000 0,0878489 0,08937562 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 95 90 0,000 0,0878489 0,08935016 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! nuclear membrane GO:0031965 92 90 0,000 0,0878489 0,08932472 ! external side of plasma membrane GO:0009897 99 90 0,000 0,0878489 0,08929929 ! growth factor binding GO:0019838 92 90 0,000 0,0878489 0,08927388 ! regulation of nucleotide metabolic process GO:0006140 93 90 0,000 0,0878489 0,08924848 ! adherens junction GO:0005912 96 90 0,000 0,0878489 0,0892231 ! ATP metabolic process GO:0046034 96 91 0,000 0,08878322 0,0901464 ! homophilic cell adhesion GO:0007156 93 91 0,000 0,08878322 0,09012078 ! ribonucleoside triphosphate biosynthetic process GO:0009201 97 91 0,000 0,08878322 0,09009517 ! protein modification by small protein conjugation GO:0032446 98 91 0,000 0,08878322 0,09006957 ! carbohydrate biosynthetic process GO:0016051 93 91 0,000 0,08878322 0,09004399 ! apical plasma membrane GO:0016324 96 91 0,000 0,08878322 0,09001843 ! intermediate filament cytoskeleton GO:0045111 93 91 0,000 0,08878322 0,08999287 ! structure-specific DNA binding GO:0043566 93 92 0,000 0,08971666 0,09091322 ! angiogenesis GO:0001525 95 92 0,000 0,08971666 0,09088743 ! glycerophospholipid metabolic process GO:0006650 98 92 0,000 0,08971666 0,09086165 ! nucleoside triphosphate biosynthetic process GO:0009142 98 92 0,000 0,08971666 0,09083589 ! clathrin-coated vesicle GO:0030136 100 92 0,000 0,08971666 0,09081014 ! gland development GO:0048732 95 92 0,000 0,08971666 0,09078441 ! DNA packaging GO:0006323 94 92 0,000 0,08971666 0,09075869 ! anatomical structure homeostasis GO:0060249 96 93 0,000 0,0906492 0,09167609 ! receptor complex GO:0043235 97 93 0,000 0,0906492 0,09165014 ! voltage-gated potassium channel activity GO:0005249 99 93 0,000 0,0906492 0,0916242 ! hormone metabolic process GO:0042445 96 93 0,000 0,0906492 0,09159827 ! translational elongation GO:0006414 97 94 0,000 0,09158085 0,09251349 ! nucleotidyltransferase activity GO:0016779 96 94 0,000 0,09158085 0,09248733 ! metalloendopeptidase activity GO:0004222 105 94 0,000 0,09158085 0,09246118 ! carbohydrate catabolic process GO:0016052 95 94 0,000 0,09158085 0,09243505 ! protein maturation GO:0051604 99 94 0,000 0,09158085 0,09240893 ! in utero embryonic development GO:0001701 97 95 0,000 0,0925116 0,09332173 ! regulation of lymphocyte activation GO:0051249 100 95 0,000 0,0925116 0,09329538 ! carboxylic acid binding GO:0031406 99 95 0,000 0,0925116 0,09326904 ! regulation of response to external stimulus GO:0032101 97 95 0,000 0,0925116 0,09324271 ! response to virus GO:0009615 102 95 0,000 0,0925116 0,0932164 ! peroxisome GO:0005777 97 96 0,000 0,09344147 0,0941268 GO:0042579|microbody, ! integral to organelle membrane GO:0031301 96 96 0,000 0,09344147 0,09410025 ! Wnt receptor signaling pathway GO:0016055 104 96 0,000 0,09344147 0,09407372 ! translation factor activity, nucleic acid binding GO:0008135 99 96 0,000 0,09344147 0,09404721 ! cell fate commitment GO:0045165 98 96 0,000 0,09344147 0,09402071 ! response to nutrient levels GO:0031667 98 96 0,000 0,09344147 0,09399422 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 101 97 0,000 0,09437045 0,09490196 ! microtubule associated complex GO:0005875 104 97 0,000 0,09437045 0,09487524 ! peptidyl-amino acid modification GO:0018193 99 97 0,000 0,09437045 0,09484854 ! anchoring junction GO:0070161 103 97 0,000 0,09437045 0,09482185 ! reproductive developmental process GO:0003006 97 97 0,000 0,09437045 0,09479518 ! regulation of GTPase activity GO:0043087 104 97 0,000 0,09437045 0,09476852 ! unfolded protein binding GO:0051082 100 98 0,000 0,09529854 0,09567362 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 99 98 0,000 0,09529854 0,09564673 ! polysaccharide metabolic process GO:0005976 102 98 0,000 0,09529854 0,09561986 ! protein modification by small protein conjugation or removal GO:0070647 105 98 0,000 0,09529854 0,095593 ! chromatin binding GO:0003682 102 99 0,000 0,09622574 0,09649596 ! nuclear chromosome GO:0000228 102 99 0,000 0,09622574 0,09646887 ! protein C-terminus binding GO:0008022 106 99 0,000 0,09622574 0,09644179 ! regulation of cellular component biogenesis GO:0044087 106 99 0,000 0,09622574 0,09641473 ! anterior/posterior pattern formation GO:0009952 102 99 0,000 0,09622574 0,09638769 ! kinase binding GO:0019900 108 99 0,000 0,09622574 0,09636066 ! tRNA metabolic process GO:0006399 101 100 0,000 0,09715205 0,097261 ! protein polymerization GO:0051258 114 100 0,000 0,09715205 0,09723374 ! cytokine binding GO:0019955 101 100 0,000 0,09715205 0,0972065 ! regulation of cell morphogenesis GO:0022604 104 100 0,000 0,09715205 0,09717927 ! chromatin assembly or disassembly GO:0006333 104 100 0,000 0,09715205 0,09715205