pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/1452-1-real-Parker_GPL887-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL887.an.zip classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle organization GO:0007051 38 27 3,000 4,633E-09 1,69E-05 ! microtubule cytoskeleton organization GO:0000226 113 87 4,000 5,587E-09 1,019E-05 ! Ran GTPase binding GO:0008536 11 9 2,000 3,486E-08 4,239E-05 ! mitotic spindle organization GO:0007052 13 12 2,000 9,117E-08 8,315E-05 ! protein serine/threonine kinase inhibitor activity GO:0030291 17 16 2,000 2,316E-07 1,69E-04 ! RNA export from nucleus GO:0006405 31 27 2,000 1,203E-06 7,317E-04 ! protein kinase inhibitor activity GO:0004860 37 34 2,000 2,454E-06 1,279E-03 ! kinase inhibitor activity GO:0019210 47 35 2,000 2,682E-06 1,223E-03 ! induction of apoptosis by intracellular signals GO:0008629 56 41 2,000 4,356E-06 1,766E-03 ! nuclear export GO:0051168 46 42 2,000 4,689E-06 1,711E-03 ! G1/S transition of mitotic cell cycle GO:0000082 54 43 2,000 5,039E-06 1,671E-03 ! positive regulation of cell-matrix adhesion GO:0001954 8 5 1,000 5,984E-06 1,819E-03 GO:0010811|positive regulation of cell-substrate adhesion, ! small-subunit processome GO:0032040 5 5 1,000 5,984E-06 1,679E-03 ! RNA polymerase II carboxy-terminal domain kinase activity GO:0008353 5 5 1,000 5,984E-06 1,559E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 55 51 2,000 8,47E-06 2,06E-03 ! microtubule nucleation GO:0007020 7 6 1,000 8,973E-06 2,046E-03 ! regulation of focal adhesion formation GO:0051893 6 6 1,000 8,973E-06 1,925E-03 ! negative regulation of protein ubiquitination GO:0031397 7 6 1,000 8,973E-06 1,818E-03 ! GDP-dissociation inhibitor activity GO:0005092 6 6 1,000 8,973E-06 1,723E-03 ! cGMP-mediated signaling GO:0019934 8 7 1,000 1,256E-05 2,29E-03 ! preribosome GO:0030684 7 7 1,000 1,256E-05 2,181E-03 ! Ras GTPase binding GO:0017016 78 61 2,000 1,457E-05 2,416E-03 ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 1,000 1,673E-05 2,654E-03 ! keratinocyte proliferation GO:0043616 9 8 1,000 1,673E-05 2,543E-03 ! regulation of S phase of mitotic cell cycle GO:0007090 8 8 1,000 1,673E-05 2,442E-03 ! positive regulation of Rho GTPase activity GO:0032321 11 8 1,000 1,673E-05 2,348E-03 ! regulation of actin filament bundle formation GO:0032231 13 8 1,000 1,673E-05 2,261E-03 GO:0051492|regulation of stress fiber formation, ! negative regulation of protein kinase activity GO:0006469 78 64 2,000 1,684E-05 2,194E-03 ! negative regulation of kinase activity GO:0033673 79 65 2,000 1,765E-05 2,22E-03 ! protein kinase regulator activity GO:0019887 74 66 2,000 1,848E-05 2,247E-03 ! small GTPase binding GO:0031267 86 69 2,000 2,113E-05 2,486E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 9 9 1,000 2,15E-05 2,451E-03 ! negative regulation of transferase activity GO:0051348 85 70 2,000 2,206E-05 2,439E-03 ! GTPase binding GO:0051020 91 74 2,000 2,607E-05 2,798E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 12 10 1,000 2,687E-05 2,8E-03 ! positive regulation of Ras GTPase activity GO:0032320 14 10 1,000 2,687E-05 2,723E-03 ! regulation of phosphatase activity GO:0010921 10 10 1,000 2,687E-05 2,649E-03 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 10 10 1,000 2,687E-05 2,579E-03 ! regulation of cell cycle process GO:0010564 113 75 2,000 2,715E-05 2,539E-03 ! kinase regulator activity GO:0019207 93 76 2,000 2,825E-05 2,576E-03 ! regulation of Ras GTPase activity GO:0032318 88 77 2,000 2,938E-05 2,614E-03 ! establishment of RNA localization GO:0051236 97 77 2,000 2,938E-05 2,552E-03 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! RNA localization GO:0006403 99 79 2,000 3,173E-05 2,692E-03 ! positive regulation of B cell proliferation GO:0030890 15 11 1,000 3,282E-05 2,721E-03 ! negative regulation of caspase activity GO:0043154 12 11 1,000 3,282E-05 2,661E-03 ! interphase of mitotic cell cycle GO:0051329 100 81 2,000 3,42E-05 2,712E-03 ! interphase GO:0051325 103 83 2,000 3,68E-05 2,856E-03 ! regulation of S phase GO:0033261 16 12 1,000 3,937E-05 2,992E-03 ! positive regulation of GTPase activity GO:0043547 17 12 1,000 3,937E-05 2,931E-03 ! midbody GO:0030496 14 12 1,000 3,937E-05 2,872E-03 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 112 91 2,000 4,847E-05 3,467E-03 ! regulation of GTPase activity GO:0043087 105 92 2,000 5,008E-05 3,513E-03 ! regulation of cytoskeleton organization GO:0051493 133 93 2,000 5,172E-05 3,56E-03 ! negative regulation of peptidase activity GO:0010466 16 14 1,000 5,423E-05 3,664E-03 ! positive regulation of cell growth GO:0030307 15 14 1,000 5,423E-05 3,597E-03 ! protein export from nucleus GO:0006611 14 14 1,000 5,423E-05 3,533E-03 ! release of cytochrome c from mitochondria GO:0001836 26 14 1,000 5,423E-05 3,471E-03 ! regulation of B cell proliferation GO:0030888 18 14 1,000 5,423E-05 3,411E-03 ! cyclin-dependent protein kinase regulator activity GO:0016538 14 14 1,000 5,423E-05 3,353E-03 ! regulation of Rho GTPase activity GO:0032319 18 15 1,000 6,255E-05 3,803E-03 ! regulation of protein ubiquitination GO:0031396 27 16 1,000 7,145E-05 4,273E-03 ! G2/M transition of mitotic cell cycle GO:0000086 22 16 1,000 7,145E-05 4,204E-03 ! skin development GO:0043588 20 17 1,000 8,094E-05 4,687E-03 ! protein phosphatase type 2A regulator activity GO:0008601 19 17 1,000 8,094E-05 4,613E-03 ! regulation of dephosphorylation GO:0035303 20 17 1,000 8,094E-05 4,542E-03 ! protein phosphatase type 2A complex GO:0000159 21 17 1,000 8,094E-05 4,474E-03 ! histone binding GO:0042393 26 17 1,000 8,094E-05 4,407E-03 ! positive regulation of cell size GO:0045793 19 18 1,000 9,101E-05 4,883E-03 ! spindle microtubule GO:0005876 27 18 1,000 9,101E-05 4,812E-03 ! negative regulation of translation GO:0017148 31 18 1,000 9,101E-05 4,743E-03 ! positive regulation of fibroblast proliferation GO:0048146 25 19 1,000 1,017E-04 5,224E-03 ! chaperone binding GO:0051087 21 20 1,000 1,129E-04 5,721E-03 ! regulation of cell-matrix adhesion GO:0001952 26 20 1,000 1,129E-04 5,643E-03 GO:0010810|regulation of cell-substrate adhesion, ! apoptotic mitochondrial changes GO:0008637 33 21 1,000 1,247E-04 6,15E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 33 22 1,000 1,372E-04 6,671E-03 ! positive regulation of B cell activation GO:0050871 26 22 1,000 1,372E-04 6,584E-03 ! nuclear chromatin GO:0000790 23 22 1,000 1,372E-04 6,498E-03 ! actin filament GO:0005884 26 24 1,000 1,637E-04 7,657E-03 ! androgen receptor binding GO:0050681 34 24 1,000 1,637E-04 7,56E-03 ! regulation of ARF GTPase activity GO:0032312 28 24 1,000 1,637E-04 7,466E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 35 24 1,000 1,637E-04 7,374E-03 ! ARF GTPase activator activity GO:0008060 29 25 1,000 1,779E-04 7,913E-03 ! positive regulation of cell adhesion GO:0045785 34 26 1,000 1,926E-04 8,466E-03 ! regulation of fibroblast proliferation GO:0048145 32 26 1,000 1,926E-04 8,365E-03 ! cyclin-dependent protein kinase activity GO:0004693 28 27 1,000 2,079E-04 8,924E-03 ! negative regulation of phosphorylation GO:0042326 30 28 1,000 2,238E-04 9,494E-03 ! condensed nuclear chromosome GO:0000794 31 30 1,000 2,573E-04 0,0107901 ! negative regulation of protein modification process GO:0031400 34 30 1,000 2,573E-04 0,01066748 ! regulation of microtubule-based process GO:0032886 41 30 1,000 2,573E-04 0,01054762 ! negative regulation of phosphorus metabolic process GO:0010563 34 31 1,000 2,749E-04 0,01114461 GO:0045936|negative regulation of phosphate metabolic process, ! protein serine/threonine phosphatase complex GO:0008287 37 33 1,000 3,119E-04 0,01250388 ! negative regulation of hydrolase activity GO:0051346 36 34 1,000 3,313E-04 0,01313489 ! regulation of B cell activation GO:0050864 40 34 1,000 3,313E-04 0,01299365 ! steroid hormone receptor binding GO:0035258 44 34 1,000 3,313E-04 0,01285542 ! androgen receptor signaling pathway GO:0030521 47 35 1,000 3,512E-04 0,01348477 ! cellular response to extracellular stimulus GO:0031668 37 36 1,000 3,717E-04 0,01412273 ! positive regulation of mast cell proliferation GO:0070668 43 36 1,000 3,717E-04 0,01397713 GO:0050671|positive regulation of lymphocyte proliferation, ! positive regulation of leukocyte proliferation GO:0070665 47 37 1,000 3,927E-04 0,01461828 GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of ARF protein signal transduction GO:0032012 44 38 1,000 4,143E-04 0,01526748 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 50 40 1,000 4,593E-04 0,01675482 ! lamellipodium GO:0030027 56 41 1,000 4,826E-04 0,01743158 ! positive regulation of growth GO:0045927 47 43 1,000 5,31E-04 0,01899021 ! protein phosphatase regulator activity GO:0019888 50 44 1,000 5,56E-04 0,01969224 ! response to UV GO:0009411 59 45 1,000 5,816E-04 0,02040056 ! phosphatase regulator activity GO:0019208 53 46 1,000 6,077E-04 0,02111497 ! response to insulin stimulus GO:0032868 57 47 1,000 6,345E-04 0,02183525 ! protein N-terminus binding GO:0047485 57 48 1,000 6,617E-04 0,02256123 ! regulation of mast cell proliferation GO:0070666 57 49 1,000 6,896E-04 0,02329271 ! DNA damage response, signal transduction GO:0042770 84 50 1,000 7,18E-04 0,02402952 ! positive regulation of organelle organization GO:0010638 69 51 1,000 7,469E-04 0,02477148 ! regulation of lymphocyte proliferation GO:0050670 61 52 1,000 7,765E-04 0,02551844 ! keratinocyte differentiation GO:0030216 60 53 1,000 8,065E-04 0,02627023 ! regulation of leukocyte proliferation GO:0070663 65 53 1,000 8,065E-04 0,02603775 GO:0032944|regulation of mononuclear cell proliferation, ! regulation of mitosis GO:0007088 79 55 1,000 8,684E-04 0,02778768 GO:0051783|regulation of nuclear division, ! steroid hormone receptor signaling pathway GO:0030518 70 55 1,000 8,684E-04 0,02754605 ! epidermal cell differentiation GO:0009913 66 58 1,000 9,653E-04 0,03035588 ! regulation of caspase activity GO:0043281 78 60 1,000 1,033E-03 0,03219686 ! nuclear pore GO:0005643 79 62 1,000 1,102E-03 0,03407484 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 77 62 1,000 1,102E-03 0,03378849 ! intracellular receptor-mediated signaling pathway GO:0030522 80 62 1,000 1,102E-03 0,03350692 ! focal adhesion GO:0005925 72 62 1,000 1,102E-03 0,03323001 ! negative regulation of cell growth GO:0030308 69 63 1,000 1,138E-03 0,03402246 ! regulation of endopeptidase activity GO:0052548 81 63 1,000 1,138E-03 0,03374586 ! regulation of actin cytoskeleton organization GO:0032956 93 64 1,000 1,174E-03 0,03453753 ! nuclear hormone receptor binding GO:0035257 79 64 1,000 1,174E-03 0,03426123 ! negative regulation of cell size GO:0045792 71 65 1,000 1,211E-03 0,03505212 ! positive regulation of lymphocyte activation GO:0051251 83 65 1,000 1,211E-03 0,03477612 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 80 65 1,000 1,211E-03 0,03450443 ! cell-substrate adherens junction GO:0005924 76 66 1,000 1,248E-03 0,03529053 ! regulation of peptidase activity GO:0052547 86 67 1,000 1,286E-03 0,03607988 ! response to peptide hormone stimulus GO:0043434 79 67 1,000 1,286E-03 0,03580447 ! regulation of actin filament-based process GO:0032970 96 67 1,000 1,286E-03 0,03553322 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 83 67 1,000 1,286E-03 0,03526605 ! cell-substrate junction GO:0030055 78 68 1,000 1,324E-03 0,03604689 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 84 68 1,000 1,324E-03 0,03577987 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 79 69 1,000 1,363E-03 0,03656007 ! positive regulation of ligase activity GO:0051351 86 70 1,000 1,402E-03 0,03734338 ! hormone receptor binding GO:0051427 85 70 1,000 1,402E-03 0,03707278 ! cell cortex GO:0005938 77 70 1,000 1,402E-03 0,03680607 ! nuclear chromosome part GO:0044454 94 70 1,000 1,402E-03 0,03654317 ! pore complex GO:0046930 89 72 1,000 1,483E-03 0,03836693 ! positive regulation of leukocyte activation GO:0002696 92 73 1,000 1,524E-03 0,03915178 ! regulation of Rho protein signal transduction GO:0035023 88 73 1,000 1,524E-03 0,03887799 ! cell-matrix adhesion GO:0007160 102 74 1,000 1,566E-03 0,0396621 ! positive regulation of cell activation GO:0050867 94 75 1,000 1,608E-03 0,04044899 ! regulation of ubiquitin-protein ligase activity GO:0051438 92 75 1,000 1,608E-03 0,04017194 ! negative regulation of growth GO:0045926 85 76 1,000 1,65E-03 0,04095806 ! cell leading edge GO:0031252 97 76 1,000 1,65E-03 0,04068132 ! condensed chromosome GO:0000793 106 76 1,000 1,65E-03 0,04040829 ! regulation of ligase activity GO:0051340 95 78 1,000 1,737E-03 0,04225462 ! cell-substrate adhesion GO:0031589 109 80 1,000 1,827E-03 0,04412844 ! rRNA processing GO:0006364 84 80 1,000 1,827E-03 0,04383812 ! mitochondrion organization GO:0007005 104 82 1,000 1,918E-03 0,04572821 ! rRNA metabolic process GO:0016072 88 83 1,000 1,964E-03 0,04653151 ! regulation of cell adhesion GO:0030155 98 83 1,000 1,964E-03 0,04623131 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 101 83 1,000 1,964E-03 0,04593495 GO:0010498|proteasomal protein catabolic process, ! adherens junction GO:0005912 100 86 1,000 2,107E-03 0,04895434 ! pigment granule GO:0048770 101 87 1,000 2,155E-03 0,04976606 GO:0042470|melanosome, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 108 91 1,000 2,355E-03 0,05403264 ! spindle GO:0005819 126 92 1,000 2,406E-03 0,05486278 ! regulation of cellular component biogenesis GO:0044087 115 92 1,000 2,406E-03 0,05452202 ! cell cycle arrest GO:0007050 103 93 1,000 2,458E-03 0,05535076 ! anchoring junction GO:0070161 108 94 1,000 2,51E-03 0,0561811 ! Wnt receptor signaling pathway GO:0016055 121 95 1,000 2,563E-03 0,05701299 ! microtubule associated complex GO:0005875 135 97 1,000 2,67E-03 0,05903692 ! nuclear chromosome GO:0000228 127 100 1,000 2,835E-03 0,0623002 ! regulation of lymphocyte activation GO:0051249 123 100 1,000 2,835E-03 0,06192714 ! response to light stimulus GO:0009416 131 100 1,000 2,835E-03 0,06155853 ! positive regulation of epidermal growth factor receptor activity GO:0045741 6 5 0,000 4E-03 0,0863523 ! negative regulation of S phase of mitotic cell cycle GO:0045749 5 5 0,000 4E-03 0,08584434 ! positive regulation of fatty acid biosynthetic process GO:0045723 5 5 0,000 4E-03 0,08534233 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 6 5 0,000 4E-03 0,08484615 ! response to superoxide GO:0000303 5 5 0,000 4E-03 0,08435571 ! negative regulation of small GTPase mediated signal transduction GO:0051058 6 5 0,000 4E-03 0,08387091 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 6 5 0,000 4E-03 0,08339165 GO:0032479|regulation of type I interferon production, ! regulation of hormone biosynthetic process GO:0046885 5 5 0,000 4E-03 0,08291783 ! calcium:cation antiporter activity GO:0015368 5 5 0,000 4E-03 0,08244937 ! quinolinate metabolic process GO:0046874 5 5 0,000 4E-03 0,08198617 ! biotin binding GO:0009374 7 5 0,000 4E-03 0,08152815 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 4E-03 0,08107521 ! tongue development GO:0043586 6 5 0,000 4E-03 0,08062728 ! nose development GO:0043584 5 5 0,000 4E-03 0,08018427 ! cell proliferation in forebrain GO:0021846 5 5 0,000 4E-03 0,07974611 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 5 5 0,000 4E-03 0,07931271 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 4E-03 0,07888399 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 5 0,000 4E-03 0,07845988 ! drug:hydrogen antiporter activity GO:0015307 6 5 0,000 4E-03 0,07804031 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! nuclear mRNA 3'-splice site recognition GO:0000389 6 5 0,000 4E-03 0,0776252 ! glycolipid transport GO:0046836 6 5 0,000 4E-03 0,07721449 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 6 5 0,000 4E-03 0,07680809 ! regulation of respiratory gaseous exchange GO:0043576 6 5 0,000 4E-03 0,07640596 ! regulation of protein export from nucleus GO:0046825 5 5 0,000 4E-03 0,07600801 ! neuron adhesion GO:0007158 5 5 0,000 4E-03 0,07561419 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 5 5 0,000 4E-03 0,07522442 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 5 0,000 4E-03 0,07483866 ! opioid peptide activity GO:0001515 6 5 0,000 4E-03 0,07445683 ! selenocysteine incorporation GO:0001514 5 5 0,000 4E-03 0,07407887 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 6 5 0,000 4E-03 0,07370474 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 8 5 0,000 4E-03 0,07333436 ! cardiac muscle cell proliferation GO:0060038 6 5 0,000 4E-03 0,07296769 GO:0014855|striated muscle cell proliferation, ! dsRNA fragmentation GO:0031050 6 5 0,000 4E-03 0,07260467 GO:0035196|gene silencing by miRNA, production of miRNAs, GO:0035195|gene silencing by miRNA, ! ruffle membrane GO:0032587 6 5 0,000 4E-03 0,07224524 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 4E-03 0,07188935 ! negative regulation of receptor-mediated endocytosis GO:0048261 7 5 0,000 4E-03 0,07153695 ! clathrin coat assembly GO:0048268 6 5 0,000 4E-03 0,07118799 ! cerebral cortex cell migration GO:0021795 5 5 0,000 4E-03 0,07084242 ! eukaryotic translation elongation factor 1 complex GO:0005853 5 5 0,000 4E-03 0,07050018 ! membrane hyperpolarization GO:0060081 5 5 0,000 4E-03 0,07016124 ! regulation of striated muscle cell differentiation GO:0051153 6 5 0,000 4E-03 0,06982554 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 4E-03 0,06949304 ! translation repressor activity GO:0030371 8 5 0,000 4E-03 0,06916369 ! positive regulation of muscle cell differentiation GO:0051149 6 5 0,000 4E-03 0,06883744 ! smooth muscle cell differentiation GO:0051145 6 5 0,000 4E-03 0,06851426 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 4E-03 0,0681941 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 5 5 0,000 4E-03 0,06787692 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 4E-03 0,06756268 GO:0046329|negative regulation of JNK cascade, ! double-stranded telomeric DNA binding GO:0003691 6 5 0,000 4E-03 0,06725133 ! negative regulation of heart contraction GO:0045822 5 5 0,000 4E-03 0,06694283 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 4E-03 0,06663716 ! microfibril GO:0001527 5 5 0,000 4E-03 0,06633426 ! troponin I binding GO:0031013 5 5 0,000 4E-03 0,06603411 ! negative regulation of viral genome replication GO:0045071 6 5 0,000 4E-03 0,06573666 ! traversing start control point of mitotic cell cycle GO:0007089 6 5 0,000 4E-03 0,06544187 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 4E-03 0,06514972 ! dorsal/ventral neural tube patterning GO:0021904 5 5 0,000 4E-03 0,06486017 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 4E-03 0,06457318 ! protein lipoylation GO:0009249 14 5 0,000 4E-03 0,06428871 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 4E-03 0,06400675 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 4E-03 0,06372724 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of isotype switching to IgG isotypes GO:0048302 5 5 0,000 4E-03 0,06345017 ! transmembrane-ephrin receptor activity GO:0005005 6 5 0,000 4E-03 0,06317549 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 4E-03 0,06290318 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 4E-03 0,06263321 ! glutamate catabolic process GO:0006538 6 5 0,000 4E-03 0,06236555 ! microvillus organization GO:0032528 5 5 0,000 4E-03 0,06210016 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 6 5 0,000 4E-03 0,06183703 ! tyrosine catabolic process GO:0006572 5 5 0,000 4E-03 0,06157611 ! response to pH GO:0009268 5 5 0,000 4E-03 0,06131739 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 5 0,000 4E-03 0,06106083 ! regulation of protein import into nucleus, translocation GO:0033158 5 5 0,000 4E-03 0,06080641 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 4E-03 0,0605541 ! polyol biosynthetic process GO:0046173 5 5 0,000 4E-03 0,06030388 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 7 5 0,000 4E-03 0,06005571 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 4E-03 0,05980958 ! fibroblast growth factor receptor activity GO:0005007 6 5 0,000 4E-03 0,05956546 ! protein-DNA loading ATPase activity GO:0033170 6 5 0,000 4E-03 0,05932333 GO:0003689|DNA clamp loader activity, ! mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276 5 5 0,000 4E-03 0,05908315 ! anaerobic glycolysis GO:0019642 5 5 0,000 4E-03 0,05884491 GO:0004459|L-lactate dehydrogenase activity, ! adenosine receptor activity, G-protein coupled GO:0001609 6 5 0,000 4E-03 0,05860859 ! regulation of retinoic acid receptor signaling pathway GO:0048385 6 5 0,000 4E-03 0,05837415 ! peroxisomal matrix GO:0005782 5 5 0,000 4E-03 0,05814159 GO:0031907|microbody lumen, ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 4E-03 0,05791087 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 6 5 0,000 4E-03 0,05768197 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 4E-03 0,05745487 ! multivesicular body GO:0005771 5 5 0,000 4E-03 0,05722956 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 4E-03 0,05700601 GO:0032430|positive regulation of phospholipase A2 activity, ! paraxial mesoderm formation GO:0048341 6 5 0,000 4E-03 0,05678419 ! insulin-like growth factor I binding GO:0031994 6 5 0,000 4E-03 0,0565641 ! mitochondrial outer membrane translocase complex GO:0005742 5 5 0,000 4E-03 0,05634571 ! peptidyl-histidine phosphorylation GO:0018106 6 5 0,000 4E-03 0,05612899 ! negative regulation of lipoprotein lipase activity GO:0051005 5 5 0,000 4E-03 0,05591394 ! epithelial cell maturation GO:0002070 14 5 0,000 4E-03 0,05570053 ! positive regulation of lipoprotein lipase activity GO:0051006 6 5 0,000 4E-03 0,05548874 ! muscle thin filament assembly GO:0030240 5 5 0,000 4E-03 0,05527855 ! regulation of protein amino acid autophosphorylation GO:0031952 5 5 0,000 4E-03 0,05506995 ! nitric-oxide synthase regulator activity GO:0030235 6 5 0,000 4E-03 0,05486292 ! negative regulation of fatty acid metabolic process GO:0045922 14 5 0,000 4E-03 0,05465745 ! regulation of glycoprotein biosynthetic process GO:0010559 6 5 0,000 4E-03 0,0544535 ! cellular glucose homeostasis GO:0001678 5 5 0,000 4E-03 0,05425107 ! positive regulation of translational initiation GO:0045948 6 5 0,000 4E-03 0,05405014 ! nonhomologous end joining complex GO:0070419 6 5 0,000 4E-03 0,05385069 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! depyrimidination GO:0045008 5 5 0,000 4E-03 0,05365271 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 4E-03 0,05345618 ! ATPase activator activity GO:0001671 5 5 0,000 4E-03 0,05326109 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 4E-03 0,05306741 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! DNA damage response, signal transduction resulting in transcription GO:0042772 17 5 0,000 4E-03 0,05287514 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! calcium sensitive guanylate cyclase activator activity GO:0008048 5 5 0,000 4E-03 0,05268425 ! regulation of cholesterol biosynthetic process GO:0045540 5 5 0,000 4E-03 0,05249474 ! positive regulation of collagen metabolic process GO:0010714 6 5 0,000 4E-03 0,05230659 GO:0032967|positive regulation of collagen biosynthetic process, ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 7 5 0,000 4E-03 0,05211978 ! regulation of protein amino acid dephosphorylation GO:0035304 7 5 0,000 4E-03 0,0519343 ! cardiac myofibril assembly GO:0055003 5 5 0,000 4E-03 0,05175013 ! anterograde axon cargo transport GO:0008089 6 5 0,000 4E-03 0,05156727 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4E-03 0,0513857 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 4E-03 0,0512054 GO:0003923|GPI-anchor transamidase activity, ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 4E-03 0,05102636 ! thiamin and derivative metabolic process GO:0042723 5 5 0,000 4E-03 0,05084856 ! protein localization to telomere GO:0070198 7 5 0,000 4E-03 0,05067201 ! response to exogenous dsRNA GO:0043330 5 5 0,000 4E-03 0,05049667 ! MutSalpha complex binding GO:0032407 7 5 0,000 4E-03 0,05032254 ! bile acid biosynthetic process GO:0006699 5 5 0,000 4E-03 0,05014962 ! negative regulation of fat cell differentiation GO:0045599 6 5 0,000 4E-03 0,04997787 ! enucleate erythrocyte differentiation GO:0043353 7 5 0,000 4E-03 0,0498073 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 4E-03 0,04963788 ! nerve growth factor binding GO:0048406 7 5 0,000 4E-03 0,04946962 ! platelet-derived growth factor binding GO:0048407 8 5 0,000 4E-03 0,04930249 ! high-density lipoprotein binding GO:0008035 6 5 0,000 4E-03 0,04913649 ! negative regulation of focal adhesion formation GO:0051895 5 5 0,000 4E-03 0,0489716 ! transcription initiation factor activity GO:0016986 5 5 0,000 4E-03 0,04880782 ! gas homeostasis GO:0033483 5 5 0,000 4E-03 0,04864513 ! Schwann cell development GO:0014044 5 5 0,000 4E-03 0,04848351 ! CD4-positive, alpha beta T cell differentiation GO:0043367 5 5 0,000 4E-03 0,04832297 ! cyclohydrolase activity GO:0019238 5 5 0,000 4E-03 0,04816349 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 4E-03 0,04800506 ! response to pheromone GO:0019236 5 5 0,000 4E-03 0,04784767 GO:0016503|pheromone receptor activity, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 5 5 0,000 4E-03 0,0476913 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 4E-03 0,04753595 ! rhombomere development GO:0021546 6 5 0,000 4E-03 0,04738162 ! alanine transport GO:0032328 6 5 0,000 4E-03 0,04722828 ! superoxide-generating NADPH oxidase activity GO:0016175 5 5 0,000 4E-03 0,04707593 ! NAD(P)H oxidase activity GO:0016174 5 5 0,000 4E-03 0,04692456 ! ventral spinal cord interneuron specification GO:0021521 7 5 0,000 4E-03 0,04677416 GO:0021514|ventral spinal cord interneuron differentiation, GO:0060579|ventral spinal cord interneuron fate commitment, ! spinal cord motor neuron cell fate specification GO:0021520 6 5 0,000 4E-03 0,04662472 ! regulation of meiosis GO:0040020 6 5 0,000 4E-03 0,04647624 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 6 5 0,000 4E-03 0,04632869 GO:0000085|G2 phase of mitotic cell cycle, ! parasympathetic nervous system development GO:0048486 5 5 0,000 4E-03 0,04618208 ! lymphocyte costimulation GO:0031294 5 5 0,000 4E-03 0,0460364 GO:0031295|T cell costimulation, ! response to tumor cell GO:0002347 7 5 0,000 4E-03 0,04589163 ! RS domain binding GO:0050733 6 5 0,000 4E-03 0,04574777 ! telomerase holoenzyme complex GO:0005697 6 5 0,000 4E-03 0,04560481 ! negative regulation of lipoprotein metabolic process GO:0050748 6 5 0,000 4E-03 0,04546274 ! B cell homeostasis GO:0001782 6 5 0,000 4E-03 0,04532155 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 4E-03 0,04518123 ! anaphase GO:0051322 7 5 0,000 4E-03 0,04504178 GO:0000090|mitotic anaphase, ! S phase GO:0051320 5 5 0,000 4E-03 0,04490319 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 4E-03 0,04476545 GO:0050820|positive regulation of coagulation, ! ribonuclease H activity GO:0004523 14 5 0,000 4E-03 0,04462856 ! AP-2 adaptor complex GO:0030122 5 5 0,000 4E-03 0,04449249 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 6 5 0,000 4E-03 0,04435726 ! diuresis GO:0030146 5 5 0,000 4E-03 0,04422284 GO:0030147|natriuresis, ! phosphatidylcholine binding GO:0031210 5 5 0,000 4E-03 0,04408924 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 4E-03 0,04395644 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 4E-03 0,04382444 ! very-low-density lipoprotein particle clearance GO:0034447 6 5 0,000 4E-03 0,04369323 ! GTP-Rho binding GO:0017049 5 5 0,000 4E-03 0,0435628 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 4E-03 0,04343315 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 4E-03 0,04330427 ! chondroitin sulfotransferase activity GO:0034481 6 5 0,000 4E-03 0,04317615 ! brown fat cell differentiation GO:0050873 5 5 0,000 4E-03 0,04304878 ! regulation of telomerase activity GO:0051972 6 5 0,000 4E-03 0,04292217 ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 4E-03 0,0427963 ! TAP complex GO:0042825 5 5 0,000 4E-03 0,04267116 ! platelet dense granule GO:0042827 6 5 0,000 4E-03 0,04254676 ! bHLH transcription factor binding GO:0043425 5 5 0,000 4E-03 0,04242308 ! secretory granule organization GO:0033363 5 5 0,000 4E-03 0,04230011 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 14 5 0,000 4E-03 0,04217786 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 4E-03 0,04205631 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 4E-03 0,04193545 ! lamin binding GO:0005521 8 5 0,000 4E-03 0,0418153 ! aldehyde-lyase activity GO:0016832 6 5 0,000 4E-03 0,04169582 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 4E-03 0,04157703 ! neural plate morphogenesis GO:0001839 6 5 0,000 4E-03 0,04145891 ! cyclosporin A binding GO:0016018 6 5 0,000 4E-03 0,04134147 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 4E-03 0,04122468 ! negative regulation of fibrinolysis GO:0051918 5 5 0,000 4E-03 0,04110856 ! positive regulation of telomere maintenance GO:0032206 7 5 0,000 4E-03 0,04099308 ! pattern recognition receptor signaling pathway GO:0002221 5 5 0,000 4E-03 0,04087826 GO:0002224|toll-like receptor signaling pathway, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 5 5 0,000 4E-03 0,04076407 ! positive regulation of blood vessel endothelial cell migration GO:0043536 6 5 0,000 4E-03 0,04065052 ! flavin-containing monooxygenase activity GO:0004499 6 5 0,000 4E-03 0,04053761 ! regulation of calcium ion transport via store-operated calcium channel activity GO:0032234 5 5 0,000 4E-03 0,04042531 ! hemopoietic progenitor cell differentiation GO:0002244 6 5 0,000 4E-03 0,04031364 ! organ or tissue specific immune response GO:0002251 6 5 0,000 4E-03 0,04020258 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 4E-03 0,04009214 ! retina homeostasis GO:0001895 5 5 0,000 4E-03 0,0399823 ! prepulse inhibition GO:0060134 8 5 0,000 4E-03 0,03987305 ! maternal placenta development GO:0001893 5 5 0,000 4E-03 0,03976441 GO:0046697|decidualization, ! endothelial cell development GO:0001885 6 5 0,000 4E-03 0,03965635 ! regulation of growth hormone secretion GO:0060123 5 5 0,000 4E-03 0,03954888 GO:0060124|positive regulation of growth hormone secretion, ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 4E-03 0,03944199 ! thiamin pyrophosphate binding GO:0030976 5 5 0,000 4E-03 0,03933568 ! protein palmitoylation GO:0018345 5 5 0,000 4E-03 0,03922994 ! protein amino acid prenylation GO:0018346 6 5 0,000 4E-03 0,03912477 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 5 0,000 4E-03 0,03902016 ! stem cell division GO:0017145 6 5 0,000 4E-03 0,0389161 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 4E-03 0,0388126 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 6 5 0,000 4E-03 0,03870965 ! organ regeneration GO:0031100 6 5 0,000 4E-03 0,03860724 ! lymphocyte apoptosis GO:0070227 6 5 0,000 4E-03 0,03850538 ! positive regulation of microtubule polymerization GO:0031116 5 5 0,000 4E-03 0,03840405 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 4E-03 0,03830325 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of developmental growth GO:0048639 6 5 0,000 4E-03 0,03820298 ! acyl carrier activity GO:0000036 5 5 0,000 4E-03 0,03810323 ! positive regulation of cAMP biosynthetic process GO:0030819 6 5 0,000 4E-03 0,03800401 GO:0030816|positive regulation of cAMP metabolic process, ! condensin complex GO:0000796 6 5 0,000 4E-03 0,03790529 ! phagocytic vesicle GO:0045335 5 5 0,000 4E-03 0,03780709 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 4E-03 0,0377094 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 4E-03 0,03761221 GO:0030823|regulation of cGMP metabolic process, ! citrulline metabolic process GO:0000052 14 5 0,000 4E-03 0,03751552 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 4E-03 0,03741933 ! polyol transport GO:0015791 8 5 0,000 4E-03 0,03732363 ! post-embryonic morphogenesis GO:0009886 7 5 0,000 4E-03 0,03722841 ! pyrimidine nucleotide-sugar transport GO:0015781 5 5 0,000 4E-03 0,03713368 ! regulation of cell adhesion mediated by integrin GO:0033628 5 5 0,000 4E-03 0,03703944 ! cell adhesion mediated by integrin GO:0033627 5 5 0,000 4E-03 0,03694567 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 4E-03 0,03685237 ! glycerol-3-phosphate metabolic process GO:0006072 6 5 0,000 4E-03 0,03675954 ! ethanol metabolic process GO:0006067 6 5 0,000 4E-03 0,03666718 GO:0006069|ethanol oxidation, GO:0034308|monohydric alcohol metabolic process, ! phosphatidic acid metabolic process GO:0046473 5 5 0,000 4E-03 0,03657528 ! cobalt ion transport GO:0006824 5 5 0,000 4E-03 0,03648385 ! cellular zinc ion homeostasis GO:0006882 6 5 0,000 4E-03 0,03639286 ! Golgi to plasma membrane transport GO:0006893 7 5 0,000 4E-03 0,03630233 ! syncytium formation by plasma membrane fusion GO:0000768 5 5 0,000 4E-03 0,03621225 GO:0007520|myoblast fusion, ! poly(U) RNA binding GO:0008266 5 5 0,000 4E-03 0,03612262 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 5 5 0,000 4E-03 0,03603343 ! sterol carrier activity GO:0005498 6 5 0,000 4E-03 0,03594467 ! adaptation of signaling pathway GO:0022401 6 5 0,000 4E-03 0,03585636 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 6 5 0,000 4E-03 0,03576848 ! response to acid GO:0001101 7 5 0,000 4E-03 0,03568102 ! fibril organization GO:0043206 5 5 0,000 4E-03 0,035594 ! malate metabolic process GO:0006108 6 5 0,000 4E-03 0,03550739 ! regulation of dopamine uptake GO:0051584 7 5 0,000 4E-03 0,03542121 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! copulation GO:0007620 5 5 0,000 4E-03 0,03533544 ! circadian sleep/wake cycle process GO:0022410 5 5 0,000 4E-03 0,03525009 GO:0042749|regulation of circadian sleep/wake cycle, GO:0045187|regulation of circadian sleep/wake cycle, sleep, ! cleavage furrow GO:0032154 6 5 0,000 4E-03 0,03516515 ! protein maturation by protein folding GO:0022417 5 5 0,000 4E-03 0,03508062 ! activation of protein kinase B activity GO:0032148 15 5 0,000 4E-03 0,03499649 ! origin recognition complex GO:0000808 5 5 0,000 4E-03 0,03491277 ! neurexin binding GO:0042043 6 5 0,000 4E-03 0,03482945 ! sensory perception of temperature stimulus GO:0050951 8 5 0,000 4E-03 0,03474652 ! protein amino acid dealkylation GO:0008214 5 5 0,000 4E-03 0,03466399 GO:0006482|protein amino acid demethylation, ! NF-kappaB-inducing kinase activity GO:0004704 5 5 0,000 4E-03 0,03458184 ! lipoic acid binding GO:0031405 5 5 0,000 4E-03 0,03450009 ! very-low-density lipoprotein particle assembly GO:0034379 5 5 0,000 4E-03 0,03441872 ! lithium ion binding GO:0031403 6 5 0,000 4E-03 0,03433774 ! grooming behavior GO:0007625 7 5 0,000 4E-03 0,03425713 ! regulation of smooth muscle cell apoptosis GO:0034391 5 5 0,000 4E-03 0,0341769 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 4E-03 0,03409705 ! lymph vessel development GO:0001945 6 5 0,000 4E-03 0,03401757 ! bicarbonate transport GO:0015701 5 5 0,000 4E-03 0,03393846 ! response to interferon-gamma GO:0034341 6 5 0,000 4E-03 0,03385972 ! protein-lysine 6-oxidase activity GO:0004720 23 5 0,000 4E-03 0,03378134 ! endothelial cell proliferation GO:0001935 8 5 0,000 4E-03 0,03370332 ! polynucleotide adenylyltransferase activity GO:0004652 5 5 0,000 4E-03 0,03362566 ! dorsal spinal cord development GO:0021516 6 5 0,000 4E-03 0,03354836 ! activation of MAPKKK activity GO:0000185 5 5 0,000 4E-03 0,03347142 ! synaptic vesicle maturation GO:0016188 6 5 0,000 4E-03 0,03339482 ! sphingoid catabolic process GO:0046521 5 5 0,000 4E-03 0,03331858 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 4E-03 0,03324268 ! neutrophil mediated immunity GO:0002446 5 5 0,000 4E-03 0,03316713 ! intercellular canaliculus GO:0046581 5 5 0,000 4E-03 0,03309192 ! dopamine binding GO:0035240 7 5 0,000 4E-03 0,03301705 GO:0004952|dopamine receptor activity, ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 5 5 0,000 4E-03 0,03294252 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 5 5 0,000 4E-03 0,03286833 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 6 5 0,000 4E-03 0,03279447 ! amine oxidase activity GO:0008131 7 5 0,000 4E-03 0,03272094 ! monocyte activation GO:0042117 9 5 0,000 4E-03 0,03264774 ! negative regulation of protein binding GO:0032091 5 5 0,000 4E-03 0,03257486 ! regulation of response to food GO:0032095 5 5 0,000 4E-03 0,03250231 ! response to food GO:0032094 6 5 0,000 4E-03 0,03243008 ! positive regulation of protein binding GO:0032092 5 5 0,000 4E-03 0,03235818 ! copper ion transmembrane transporter activity GO:0005375 5 5 0,000 4E-03 0,03228659 ! regulation of ryanodine-sensitive calcium-release channel activity GO:0060314 6 5 0,000 4E-03 0,03221532 ! hedgehog receptor activity GO:0008158 5 5 0,000 4E-03 0,03214436 ! lipoprotein catabolic process GO:0042159 5 5 0,000 4E-03 0,03207371 ! substrate-bound cell migration, cell extension GO:0006930 7 5 0,000 4E-03 0,03200337 ! purine salvage GO:0043101 7 5 0,000 4E-03 0,03193334 ! positive regulation of catecholamine secretion GO:0033605 5 5 0,000 4E-03 0,03186362 ! ciliary rootlet GO:0035253 5 5 0,000 4E-03 0,0317942 ! myosin heavy chain binding GO:0032036 5 5 0,000 4E-03 0,03172508 ! nucleobase transport GO:0015851 5 5 0,000 4E-03 0,03165626 ! sodium ion transmembrane transporter activity GO:0015081 6 5 0,000 4E-03 0,03158774 ! GPI anchor binding GO:0034235 6 5 0,000 4E-03 0,03151952 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 4E-03 0,03145159 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! thrombin receptor activity GO:0015057 5 5 0,000 4E-03 0,03138395 ! palmitoyl-CoA hydrolase activity GO:0016290 5 5 0,000 4E-03 0,03131661 ! basic amino acid transport GO:0015802 5 5 0,000 4E-03 0,03124955 ! dendritic shaft GO:0043198 5 5 0,000 4E-03 0,03118277 ! terminal button GO:0043195 7 5 0,000 4E-03 0,03111629 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 4E-03 0,03105008 GO:0016274|protein-arginine N-methyltransferase activity, ! neuronal ion channel clustering GO:0045161 5 5 0,000 4E-03 0,03098416 ! transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity GO:0030618 6 5 0,000 4E-03 0,03091851 ! homeostasis of number of cells within a tissue GO:0048873 7 5 0,000 4E-03 0,03085315 ! negative regulation of peptide secretion GO:0002792 5 5 0,000 4E-03 0,03078805 GO:0046676|negative regulation of insulin secretion, ! neural nucleus development GO:0048857 6 5 0,000 4E-03 0,03072324 ! response to UV-C GO:0010225 15 5 0,000 4E-03 0,03065869 ! positive regulation of organ growth GO:0046622 5 5 0,000 4E-03 0,03059442 ! response to arsenic GO:0046685 6 5 0,000 4E-03 0,03053041 ! IgE binding GO:0019863 5 5 0,000 4E-03 0,03046668 ! positive regulation of T cell cytokine production GO:0002726 5 5 0,000 4E-03 0,0304032 GO:0032743|positive regulation of interleukin-2 production, ! transcription-coupled nucleotide-excision repair GO:0006283 5 5 0,000 4E-03 0,03034 ! monoamine transmembrane transporter activity GO:0008504 6 5 0,000 4E-03 0,03027705 ! response to copper ion GO:0046688 5 5 0,000 4E-03 0,03021436 ! response to cadmium ion GO:0046686 5 5 0,000 4E-03 0,03015194 ! tetrahydrofolate metabolic process GO:0046653 5 5 0,000 4E-03 0,03008977 ! regulation of interleukin-1 beta production GO:0032651 5 5 0,000 4E-03 0,03002786 ! protein autoprocessing GO:0016540 6 5 0,000 4E-03 0,0299662 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 4E-03 0,02990479 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 4E-03 0,02984364 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 4E-03 0,02978273 GO:0005218|intracellular ligand-gated calcium channel activity, ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 4E-03 0,02972207 ! mitotic recombination GO:0006312 15 5 0,000 4E-03 0,02966166 ! negative regulation of interleukin-6 production GO:0032715 6 5 0,000 4E-03 0,0296015 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 4E-03 0,02954157 ! membrane to membrane docking GO:0022614 5 5 0,000 4E-03 0,02948189 ! regulation of transcription from RNA polymerase I promoter GO:0006356 14 5 0,000 4E-03 0,02942246 ! translation activator activity GO:0008494 5 5 0,000 4E-03 0,02936326 ! somatostatin receptor activity GO:0004994 5 5 0,000 4E-03 0,02930429 ! melanocortin receptor activity GO:0004977 6 5 0,000 4E-03 0,02924557 ! serine-type carboxypeptidase activity GO:0004185 5 5 0,000 4E-03 0,02918708 GO:0070008|serine-type exopeptidase activity, ! protein phosphatase 2A binding GO:0051721 6 5 0,000 4E-03 0,02912882 ! salivary gland morphogenesis GO:0007435 5 5 0,000 4E-03 0,02907079 ! galactosidase activity GO:0015925 5 5 0,000 4E-03 0,029013 ! prostaglandin E receptor activity GO:0004957 7 5 0,000 4E-03 0,02895543 ! cellular response to nutrient GO:0031670 5 5 0,000 4E-03 0,0288981 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 4E-03 0,02884098 ! L-cystine transmembrane transporter activity GO:0015184 5 5 0,000 4E-03 0,0287841 ! glycine transmembrane transporter activity GO:0015187 7 5 0,000 4E-03 0,02872744 ! L-gamma-aminobutyric acid transmembrane transporter activity GO:0015185 6 5 0,000 4E-03 0,028671 ! A band GO:0031672 5 5 0,000 4E-03 0,02861478 ! heat generation GO:0031649 5 5 0,000 4E-03 0,02855878 ! flagellum organization GO:0043064 5 5 0,000 4E-03 0,028503 GO:0009296|flagellum assembly, ! tricarboxylic acid cycle enzyme complex GO:0045239 6 5 0,000 4E-03 0,02844744 ! disaccharide metabolic process GO:0005984 6 5 0,000 4E-03 0,0283921 ! glycogen catabolic process GO:0005980 16 5 0,000 4E-03 0,02833697 ! dopamine biosynthetic process GO:0042416 6 5 0,000 4E-03 0,02828205 ! 5'-3' exonuclease activity GO:0008409 14 5 0,000 4E-03 0,02822735 ! chromocenter GO:0010369 5 5 0,000 4E-03 0,02817285 ! glial cell migration GO:0008347 5 5 0,000 4E-03 0,02811857 ! epidermal growth factor receptor binding GO:0005154 7 5 0,000 4E-03 0,0280645 ! calcium-dependent phospholipase A2 activity GO:0047498 5 5 0,000 4E-03 0,02801063 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 4E-03 0,02795697 ! growth hormone receptor binding GO:0005131 5 5 0,000 4E-03 0,02790351 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 4E-03 0,02785026 ! negative regulation of smooth muscle contraction GO:0045986 7 5 0,000 4E-03 0,02779722 ! aminomethyltransferase activity GO:0004047 5 5 0,000 4E-03 0,02774437 ! aminoacylase activity GO:0004046 5 5 0,000 4E-03 0,02769172 ! penetration of zona pellucida GO:0007341 6 5 0,000 4E-03 0,02763928 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 5 5 0,000 4E-03 0,02758703 ! nucleus localization GO:0051647 5 5 0,000 4E-03 0,02753498 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 5 5 0,000 4E-03 0,02748312 ! carnitine metabolic process GO:0009437 5 5 0,000 4E-03 0,02743146 GO:0006577|betaine metabolic process, ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 4,799E-03 0,03284371 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 0,000 4,799E-03 0,03278221 ! regulation of helicase activity GO:0051095 6 6 0,000 4,799E-03 0,03272093 ! response to oxygen radical GO:0000305 6 6 0,000 4,799E-03 0,03265989 ! positive regulation of axon extension GO:0045773 7 6 0,000 4,799E-03 0,03259907 ! forebrain neuron differentiation GO:0021879 6 6 0,000 4,799E-03 0,03253847 ! forebrain regionalization GO:0021871 7 6 0,000 4,799E-03 0,03247811 ! meiotic prophase I GO:0007128 7 6 0,000 4,799E-03 0,03241796 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 4,799E-03 0,03235804 ! inositol trisphosphate phosphatase activity GO:0046030 8 6 0,000 4,799E-03 0,03229834 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 4,799E-03 0,03223886 ! SMAD protein nuclear translocation GO:0007184 7 6 0,000 4,799E-03 0,03217959 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 9 6 0,000 4,799E-03 0,03212055 ! carbohydrate phosphorylation GO:0046835 7 6 0,000 4,799E-03 0,03206172 ! phosphoinositide 3-kinase binding GO:0043548 6 6 0,000 4,799E-03 0,03200311 ! protein amino acid sulfation GO:0006477 9 6 0,000 4,799E-03 0,03194471 GO:0051923|sulfation, ! diphosphotransferase activity GO:0016778 7 6 0,000 4,799E-03 0,03188652 ! establishment of tissue polarity GO:0007164 8 6 0,000 4,799E-03 0,03182854 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 4,799E-03 0,03177078 ! receptor guanylyl cyclase signaling pathway GO:0007168 6 6 0,000 4,799E-03 0,03171322 ! embryonic camera-type eye development GO:0031076 9 6 0,000 4,799E-03 0,03165588 GO:0048596|embryonic camera-type eye morphogenesis, ! hexokinase activity GO:0004396 7 6 0,000 4,799E-03 0,03159874 ! regulation of mitochondrial membrane permeability GO:0046902 7 6 0,000 4,799E-03 0,0315418 ! neurofilament cytoskeleton organization GO:0060052 6 6 0,000 4,799E-03 0,03148507 ! Notch receptor processing GO:0007220 7 6 0,000 4,799E-03 0,03142854 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 8 6 0,000 4,799E-03 0,03137222 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 7 6 0,000 4,799E-03 0,0313161 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 4,799E-03 0,03126018 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 4,799E-03 0,03120445 ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 6 0,000 4,799E-03 0,03114893 ! neurofilament GO:0005883 7 6 0,000 4,799E-03 0,0310936 ! glial cell fate commitment GO:0021781 7 6 0,000 4,799E-03 0,03103847 ! cytoplasmic dynein complex GO:0005868 7 6 0,000 4,799E-03 0,03098354 ! dynactin complex GO:0005869 7 6 0,000 4,799E-03 0,0309288 ! fibroblast growth factor receptor antagonist activity GO:0030353 7 6 0,000 4,799E-03 0,03087425 GO:0005152|interleukin-1 receptor antagonist activity, ! enoyl-CoA hydratase activity GO:0004300 6 6 0,000 4,799E-03 0,03081989 ! oocyte maturation GO:0001556 6 6 0,000 4,799E-03 0,03076573 ! DNA replication origin binding GO:0003688 6 6 0,000 4,799E-03 0,03071175 ! reflex GO:0060004 10 6 0,000 4,799E-03 0,03065797 ! positive regulation of glycolysis GO:0045821 6 6 0,000 4,799E-03 0,03060437 ! parathyroid gland development GO:0060017 6 6 0,000 4,799E-03 0,03055096 ! anagen GO:0042640 7 6 0,000 4,799E-03 0,03049773 ! protein-cofactor linkage GO:0018065 15 6 0,000 4,799E-03 0,03044469 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 6 6 0,000 4,799E-03 0,03039184 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! protein targeting to ER GO:0045047 7 6 0,000 4,799E-03 0,03033917 GO:0006614|SRP-dependent cotranslational protein targeting to membrane, ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 6 6 0,000 4,799E-03 0,03028668 ! skeletal myofibril assembly GO:0014866 6 6 0,000 4,799E-03 0,03023437 ! structural constituent of tooth enamel GO:0030345 7 6 0,000 4,799E-03 0,03018224 ! cysteine metabolic process GO:0006534 7 6 0,000 4,799E-03 0,03013029 ! glycine catabolic process GO:0006546 6 6 0,000 4,799E-03 0,03007852 ! adenohypophysis development GO:0021984 6 6 0,000 4,799E-03 0,03002693 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 6 6 0,000 4,799E-03 0,02997551 ! deoxyribonucleotide biosynthetic process GO:0009263 7 6 0,000 4,799E-03 0,02992427 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 6 0,000 4,799E-03 0,02987321 ! proline biosynthetic process GO:0006561 8 6 0,000 4,799E-03 0,02982232 ! tryptophan metabolic process GO:0006568 6 6 0,000 4,799E-03 0,0297716 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 6 6 0,000 4,799E-03 0,02972105 ! thyroid hormone generation GO:0006590 6 6 0,000 4,799E-03 0,02967068 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 4,799E-03 0,02962047 ! retinoid X receptor binding GO:0046965 7 6 0,000 4,799E-03 0,02957044 ! proton-transporting V-type ATPase, V0 domain GO:0033179 6 6 0,000 4,799E-03 0,02952057 ! transforming growth factor beta receptor activity, type I GO:0005025 7 6 0,000 4,799E-03 0,02947087 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 4,799E-03 0,02942134 ! sister chromatid cohesion GO:0007062 6 6 0,000 4,799E-03 0,02937198 ! retinoic acid receptor signaling pathway GO:0048384 9 6 0,000 4,799E-03 0,02932278 ! positive regulation of transporter activity GO:0032411 8 6 0,000 4,799E-03 0,02927374 GO:0032414|positive regulation of ion transmembrane transporter activity, ! cerebral cortex neuron differentiation GO:0021895 7 6 0,000 4,799E-03 0,02922487 ! regulation of fatty acid beta-oxidation GO:0031998 6 6 0,000 4,799E-03 0,02917617 ! p53 binding GO:0002039 6 6 0,000 4,799E-03 0,02912762 ! demethylase activity GO:0032451 6 6 0,000 4,799E-03 0,02907923 ! positive regulation of nitric-oxide synthase activity GO:0051000 6 6 0,000 4,799E-03 0,02903101 ! regulation of platelet activation GO:0010543 7 6 0,000 4,799E-03 0,02898295 ! lipid phosphatase activity GO:0042577 7 6 0,000 4,799E-03 0,02893504 ! lens morphogenesis in camera-type eye GO:0002089 6 6 0,000 4,799E-03 0,02888729 ! guanylate cyclase activator activity GO:0030250 6 6 0,000 4,799E-03 0,0288397 GO:0010853|cyclase activator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 8 6 0,000 4,799E-03 0,02879227 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of exocytosis GO:0045921 6 6 0,000 4,799E-03 0,02874499 ! protein tyrosine kinase activator activity GO:0030296 8 6 0,000 4,799E-03 0,02869787 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 4,799E-03 0,0286509 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of steroid metabolic process GO:0045940 6 6 0,000 4,799E-03 0,02860408 ! LIM domain binding GO:0030274 7 6 0,000 4,799E-03 0,02855742 ! negative regulation of translational initiation GO:0045947 6 6 0,000 4,799E-03 0,02851091 ! positive regulation vascular endothelial growth factor production GO:0010575 6 6 0,000 4,799E-03 0,02846455 ! 5S class rRNA transcription GO:0042791 6 6 0,000 4,799E-03 0,02841834 GO:0042797|tRNA transcription from RNA polymerase III promoter, GO:0000127|transcription factor TFIIIC complex, ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 4,799E-03 0,02837228 ! axon guidance receptor activity GO:0008046 6 6 0,000 4,799E-03 0,02832637 ! zinc ion homeostasis GO:0055069 7 6 0,000 4,799E-03 0,02828061 ! positive regulation of gliogenesis GO:0014015 7 6 0,000 4,799E-03 0,028235 GO:0045687|positive regulation of glial cell differentiation, ! centrosome duplication GO:0051298 7 6 0,000 4,799E-03 0,02818953 ! protein targeting to lysosome GO:0006622 6 6 0,000 4,799E-03 0,02814421 ! hyaluronan metabolic process GO:0030212 8 6 0,000 4,799E-03 0,02809904 ! protein retention in ER lumen GO:0006621 6 6 0,000 4,799E-03 0,02805401 ! ventricular cardiac muscle cell differentiation GO:0055012 8 6 0,000 4,799E-03 0,02800912 ! circadian sleep/wake cycle GO:0042745 7 6 0,000 4,799E-03 0,02796438 ! dynein binding GO:0045502 6 6 0,000 4,799E-03 0,02791978 ! regulation of dendrite development GO:0050773 6 6 0,000 4,799E-03 0,02787532 ! peptidyl-arginine modification GO:0018195 6 6 0,000 4,799E-03 0,027831 ! eating behavior GO:0042755 7 6 0,000 4,799E-03 0,02778682 ! protein localization to chromosome GO:0034502 8 6 0,000 4,799E-03 0,02774279 ! Hsp90 protein binding GO:0051879 7 6 0,000 4,799E-03 0,02769889 ! glycolipid binding GO:0051861 7 6 0,000 4,799E-03 0,02765513 ! MutLalpha complex binding GO:0032405 8 6 0,000 4,799E-03 0,02761151 ! mast cell activation GO:0045576 6 6 0,000 4,799E-03 0,02756803 ! nucleoside catabolic process GO:0009164 7 6 0,000 4,799E-03 0,02752468 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 4,799E-03 0,02748147 ! molybdopterin cofactor biosynthetic process GO:0032324 15 6 0,000 4,799E-03 0,0274384 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 4,799E-03 0,02739546 ! RNA polymerase II transcription elongation factor activity GO:0016944 6 6 0,000 4,799E-03 0,02735266 ! lipoxygenase activity GO:0016165 6 6 0,000 4,799E-03 0,02730998 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 4,799E-03 0,02726744 ! alpha DNA polymerase:primase complex GO:0005658 16 6 0,000 4,799E-03 0,02722504 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 4,799E-03 0,02718276 ! DNA replication factor C complex GO:0005663 7 6 0,000 4,799E-03 0,02714062 ! DNA replication factor A complex GO:0005662 7 6 0,000 4,799E-03 0,02709861 ! establishment of chromosome localization GO:0051303 15 6 0,000 4,799E-03 0,02705672 GO:0050000|chromosome localization, ! cilium morphogenesis GO:0060271 6 6 0,000 4,799E-03 0,02701497 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 4,799E-03 0,02697334 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 4,799E-03 0,02693184 ! chromatin assembly complex GO:0005678 16 6 0,000 4,799E-03 0,02689047 ! sex chromatin GO:0001739 6 6 0,000 4,799E-03 0,02684923 GO:0000803|sex chromosome, ! morphogenesis of a polarized epithelium GO:0001738 7 6 0,000 4,799E-03 0,02680812 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 7 6 0,000 4,799E-03 0,02676712 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! SAP kinase activity GO:0016909 7 6 0,000 4,799E-03 0,02672626 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 4,799E-03 0,02668552 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 7 6 0,000 4,799E-03 0,0266449 ! positive regulation of pseudopodium assembly GO:0031274 6 6 0,000 4,799E-03 0,02660441 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipoprotein metabolic process GO:0050746 7 6 0,000 4,799E-03 0,02656404 ! phosphatidylserine binding GO:0001786 6 6 0,000 4,799E-03 0,02652379 ! alpha-mannosidase activity GO:0004559 8 6 0,000 4,799E-03 0,02648366 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 6 0,000 4,799E-03 0,02644365 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 4,799E-03 0,02640377 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 11 6 0,000 4,799E-03 0,026364 GO:0002820|negative regulation of adaptive immune response, ! myeloid dendritic cell activation GO:0001773 8 6 0,000 4,799E-03 0,02632436 GO:0043011|myeloid dendritic cell differentiation, ! immunological synapse GO:0001772 6 6 0,000 4,799E-03 0,02628483 ! leading edge membrane GO:0031256 8 6 0,000 4,799E-03 0,02624543 ! photoreceptor connecting cilium GO:0032391 7 6 0,000 4,799E-03 0,02620614 ! CARD domain binding GO:0050700 6 6 0,000 4,799E-03 0,02616696 ! regulation of muscle cell apoptosis GO:0010660 7 6 0,000 4,799E-03 0,02612791 ! COPII vesicle coat GO:0030127 7 6 0,000 4,799E-03 0,02608897 GO:0012507|ER to Golgi transport vesicle membrane, ! molybdenum ion binding GO:0030151 15 6 0,000 4,799E-03 0,02605015 ! glutathione biosynthetic process GO:0006750 7 6 0,000 4,799E-03 0,02601144 ! positive regulation of erythrocyte differentiation GO:0045648 8 6 0,000 4,799E-03 0,02597285 ! positive regulation of epidermis development GO:0045684 8 6 0,000 4,799E-03 0,02593437 ! proteasome regulator activity GO:0010860 6 6 0,000 4,799E-03 0,025896 ! ceramidase activity GO:0017040 6 6 0,000 4,799E-03 0,02585775 ! antibiotic transport GO:0042891 7 6 0,000 4,799E-03 0,02581962 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 4,799E-03 0,02578159 ! regulation of T-helper cell differentiation GO:0045622 6 6 0,000 4,799E-03 0,02574368 ! sodium channel regulator activity GO:0017080 6 6 0,000 4,799E-03 0,02570587 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 4,799E-03 0,02566818 ! regulation of protein homodimerization activity GO:0043496 9 6 0,000 4,799E-03 0,0256306 ! response to fluid shear stress GO:0034405 6 6 0,000 4,799E-03 0,02559313 ! lymph node development GO:0048535 6 6 0,000 4,799E-03 0,02555577 ! negative regulation of viral reproduction GO:0048525 7 6 0,000 4,799E-03 0,02551851 ! triglyceride catabolic process GO:0019433 15 6 0,000 4,799E-03 0,02548137 ! positive regulation of fatty acid oxidation GO:0046321 6 6 0,000 4,799E-03 0,02544433 ! ectodermal gut morphogenesis GO:0048567 7 6 0,000 4,799E-03 0,0254074 GO:0007439|ectodermal gut development, ! T cell activation during immune response GO:0002286 6 6 0,000 4,799E-03 0,02537058 ! negative regulation of lipase activity GO:0060192 6 6 0,000 4,799E-03 0,02533386 ! activation of innate immune response GO:0002218 6 6 0,000 4,799E-03 0,02529725 GO:0002758|innate immune response-activating signal transduction, ! regulation of telomere maintenance via telomerase GO:0032210 7 6 0,000 4,799E-03 0,02526075 ! sarcoglycan complex GO:0016012 8 6 0,000 4,799E-03 0,02522435 ! natural killer cell mediated immunity GO:0002228 7 6 0,000 4,799E-03 0,02518806 GO:0042267|natural killer cell mediated cytotoxicity, ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 6 6 0,000 4,799E-03 0,02515187 ! neural plate development GO:0001840 7 6 0,000 4,799E-03 0,02511578 ! regulation of synaptic transmission, GABAergic GO:0032228 15 6 0,000 4,799E-03 0,0250798 ! catecholamine transport GO:0051937 6 6 0,000 4,799E-03 0,02504392 ! ether hydrolase activity GO:0016803 7 6 0,000 4,799E-03 0,02500814 ! FACIT collagen GO:0005593 6 6 0,000 4,799E-03 0,02497247 ! lactate dehydrogenase activity GO:0004457 6 6 0,000 4,799E-03 0,02493689 ! regulation of T cell receptor signaling pathway GO:0050856 7 6 0,000 4,799E-03 0,02490142 ! collagen type IV GO:0005587 6 6 0,000 4,799E-03 0,02486605 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 4,799E-03 0,02483078 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 7 6 0,000 4,799E-03 0,02479561 ! drug metabolic process GO:0017144 6 6 0,000 4,799E-03 0,02476054 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 4,799E-03 0,02472556 ! negative regulation of synaptic transmission GO:0050805 6 6 0,000 4,799E-03 0,02469069 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 4,799E-03 0,02465591 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 4,799E-03 0,02462124 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 6 6 0,000 4,799E-03 0,02458666 ! regulation of microtubule polymerization GO:0031113 6 6 0,000 4,799E-03 0,02455217 ! cellular anion homeostasis GO:0030002 6 6 0,000 4,799E-03 0,02451779 GO:0055081|anion homeostasis, ! regulation of MHC class II biosynthetic process GO:0045346 6 6 0,000 4,799E-03 0,0244835 ! negative regulation of fibroblast proliferation GO:0048147 6 6 0,000 4,799E-03 0,0244493 ! behavioral response to cocaine GO:0048148 9 6 0,000 4,799E-03 0,0244152 ! translation initiation factor binding GO:0031369 6 6 0,000 4,799E-03 0,0243812 ! nucleotide-sugar transport GO:0015780 6 6 0,000 4,799E-03 0,02434729 ! sulfur amino acid transmembrane transporter activity GO:0000099 6 6 0,000 4,799E-03 0,02431347 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 4,799E-03 0,02427975 ! quaternary ammonium group binding GO:0050997 7 6 0,000 4,799E-03 0,02424612 ! actin-dependent ATPase activity GO:0030898 7 6 0,000 4,799E-03 0,02421259 ! reproductive behavior GO:0019098 8 6 0,000 4,799E-03 0,02417914 ! response to growth hormone stimulus GO:0060416 7 6 0,000 4,799E-03 0,02414579 GO:0060396|growth hormone receptor signaling pathway, ! negative regulation of JAK-STAT cascade GO:0046426 8 6 0,000 4,799E-03 0,02411253 ! nucleotide-excision repair, DNA incision GO:0033683 6 6 0,000 4,799E-03 0,02407937 ! negative regulation of cell-cell adhesion GO:0022408 8 6 0,000 4,799E-03 0,02404629 ! positive regulation of cell-cell adhesion GO:0022409 7 6 0,000 4,799E-03 0,0240133 ! induction of positive chemotaxis GO:0050930 7 6 0,000 4,799E-03 0,02398041 ! cohesin complex GO:0008278 6 6 0,000 4,799E-03 0,0239476 ! regulation of collagen biosynthetic process GO:0032965 7 6 0,000 4,799E-03 0,02391489 ! citrate metabolic process GO:0006101 7 6 0,000 4,799E-03 0,02388226 ! myelin sheath GO:0043209 8 6 0,000 4,799E-03 0,02384973 ! phototransduction, visible light GO:0007603 6 6 0,000 4,799E-03 0,02381728 ! opsonization GO:0008228 7 6 0,000 4,799E-03 0,02378492 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 4,799E-03 0,02375264 ! regulation of dopamine metabolic process GO:0042053 8 6 0,000 4,799E-03 0,02372046 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 7 6 0,000 4,799E-03 0,02368836 ! regulation of potassium ion transport GO:0043266 8 6 0,000 4,799E-03 0,02365635 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 4,799E-03 0,02362443 ! chemoattractant activity GO:0042056 6 6 0,000 4,799E-03 0,02359259 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 8 6 0,000 4,799E-03 0,02356083 ! low-density lipoprotein particle remodeling GO:0034374 6 6 0,000 4,799E-03 0,02352917 ! ornithine decarboxylase regulator activity GO:0042979 6 6 0,000 4,799E-03 0,02349758 ! leukocyte degranulation GO:0043299 6 6 0,000 4,799E-03 0,02346608 ! bile acid and bile salt transport GO:0015721 7 6 0,000 4,799E-03 0,02343467 ! regulation of cytokine-mediated signaling pathway GO:0001959 11 6 0,000 4,799E-03 0,02340334 ! mitochondrial genome maintenance GO:0000002 6 6 0,000 4,799E-03 0,0233721 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 6 0,000 4,799E-03 0,02334093 ! DNA topoisomerase activity GO:0003916 6 6 0,000 4,799E-03 0,02330985 ! protein geranylgeranyltransferase activity GO:0004661 7 6 0,000 4,799E-03 0,02327886 ! ceramide biosynthetic process GO:0046513 6 6 0,000 4,799E-03 0,02324794 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 4,799E-03 0,02321711 ! activin receptor activity GO:0017002 7 6 0,000 4,799E-03 0,02318636 ! astrocyte differentiation GO:0048708 6 6 0,000 4,799E-03 0,02315569 ! syncytium formation GO:0006949 6 6 0,000 4,799E-03 0,0231251 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 4,799E-03 0,02309459 ! neutrophil activation GO:0042119 6 6 0,000 4,799E-03 0,02306416 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 4,799E-03 0,02303381 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 4,799E-03 0,02300355 ! positive regulation of activated T cell proliferation GO:0042104 7 6 0,000 4,799E-03 0,02297336 ! positive transcription elongation factor activity GO:0008159 7 6 0,000 4,799E-03 0,02294325 ! NuA4 histone acetyltransferase complex GO:0035267 8 6 0,000 4,799E-03 0,02291322 ! cellular polysaccharide catabolic process GO:0044247 17 6 0,000 4,799E-03 0,02288327 GO:0009251|glucan catabolic process, ! response to salt stress GO:0009651 7 6 0,000 4,799E-03 0,02285339 ! neuron apoptosis GO:0051402 7 6 0,000 4,799E-03 0,0228236 ! folic acid transport GO:0015884 8 6 0,000 4,799E-03 0,02279388 ! carnitine transport GO:0015879 6 6 0,000 4,799E-03 0,02276424 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 4,799E-03 0,02273467 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! parturition GO:0007567 7 6 0,000 4,799E-03 0,02270519 ! S-methyltransferase activity GO:0008172 6 6 0,000 4,799E-03 0,02267578 ! phospholipase D activity GO:0004630 6 6 0,000 4,799E-03 0,02264644 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 4,799E-03 0,02261718 ! intercalated disc GO:0014704 8 6 0,000 4,799E-03 0,022588 ! G2/M transition checkpoint GO:0031576 24 6 0,000 4,799E-03 0,02255889 GO:0031572|G2/M transition DNA damage checkpoint, ! interaction with symbiont GO:0051702 6 6 0,000 4,799E-03 0,02252986 ! IgG binding GO:0019864 6 6 0,000 4,799E-03 0,0225009 ! regulation of T cell cytokine production GO:0002724 6 6 0,000 4,799E-03 0,02247201 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 6 6 0,000 4,799E-03 0,0224432 ! benzodiazepine receptor activity GO:0008503 7 6 0,000 4,799E-03 0,02241447 ! antigen processing and presentation of exogenous antigen GO:0019884 7 6 0,000 4,799E-03 0,0223858 ! regulation of T cell differentiation in the thymus GO:0033081 7 6 0,000 4,799E-03 0,02235721 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 6 6 0,000 4,799E-03 0,0223287 ! regulation of interleukin-4 production GO:0032673 6 6 0,000 4,799E-03 0,02230025 ! dendrite morphogenesis GO:0048813 7 6 0,000 4,799E-03 0,02227188 ! regulation of interleukin-1 production GO:0032652 7 6 0,000 4,799E-03 0,02224358 ! ribosomal large subunit biogenesis GO:0042273 7 6 0,000 4,799E-03 0,02221535 ! regulation of myeloid cell apoptosis GO:0033032 8 6 0,000 4,799E-03 0,0221872 ! nucleosome disassembly GO:0006337 7 6 0,000 4,799E-03 0,02215911 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! general transcriptional repressor activity GO:0016565 7 6 0,000 4,799E-03 0,0221311 ! regulation of mast cell activation GO:0033003 6 6 0,000 4,799E-03 0,02210316 ! tetracycline transporter activity GO:0008493 7 6 0,000 4,799E-03 0,02207528 GO:0042895|antibiotic transporter activity, ! guanylyltransferase activity GO:0070568 7 6 0,000 4,799E-03 0,02204748 ! receptor internalization GO:0031623 8 6 0,000 4,799E-03 0,02201975 ! N-formyl peptide receptor activity GO:0004982 6 6 0,000 4,799E-03 0,02199208 ! coenzyme A biosynthetic process GO:0015937 6 6 0,000 4,799E-03 0,02196449 ! histamine receptor activity GO:0004969 7 6 0,000 4,799E-03 0,02193697 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 6 0,000 4,799E-03 0,02190951 ! pyrimidine nucleotide sugar transmembrane transporter activity GO:0015165 6 6 0,000 4,799E-03 0,02188212 ! protein deubiquitination GO:0016579 6 6 0,000 4,799E-03 0,02185481 ! axonal fasciculation GO:0007413 7 6 0,000 4,799E-03 0,02182756 ! basic amino acid transmembrane transporter activity GO:0015174 6 6 0,000 4,799E-03 0,02180037 ! cytidine deaminase activity GO:0004126 6 6 0,000 4,799E-03 0,02177326 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 4,799E-03 0,02174621 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 4,799E-03 0,02171923 GO:0015991|ATP hydrolysis coupled proton transport, ! alpha-adrenergic receptor activity GO:0004936 9 6 0,000 4,799E-03 0,02169232 ! cytochrome-b5 reductase activity GO:0004128 7 6 0,000 4,799E-03 0,02166547 ! glycine binding GO:0016594 9 6 0,000 4,799E-03 0,02163869 ! apical protein localization GO:0045176 7 6 0,000 4,799E-03 0,02161197 ! ankyrin binding GO:0030506 6 6 0,000 4,799E-03 0,02158533 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 4,799E-03 0,02155874 ! thyroid hormone receptor activity GO:0004887 7 6 0,000 4,799E-03 0,02153223 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 4,799E-03 0,02150577 ! progesterone metabolic process GO:0042448 6 6 0,000 4,799E-03 0,02147939 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 7 6 0,000 4,799E-03 0,02145306 ! type II transforming growth factor beta receptor binding GO:0005114 6 6 0,000 4,799E-03 0,0214268 ! ATP catabolic process GO:0006200 6 6 0,000 4,799E-03 0,02140061 ! CoA carboxylase activity GO:0016421 6 6 0,000 4,799E-03 0,02137448 ! determination of adult lifespan GO:0008340 6 6 0,000 4,799E-03 0,02134841 ! S-acyltransferase activity GO:0016417 6 6 0,000 4,799E-03 0,02132241 ! somatic stem cell maintenance GO:0035019 6 6 0,000 4,799E-03 0,02129647 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 4,799E-03 0,02127059 ! IkappaB kinase complex GO:0008385 7 6 0,000 4,799E-03 0,02124478 ! nucleobase transmembrane transporter activity GO:0015205 7 6 0,000 4,799E-03 0,02121903 ! store-operated calcium channel activity GO:0015279 6 6 0,000 4,799E-03 0,02119334 ! alkaline phosphatase activity GO:0004035 7 6 0,000 4,799E-03 0,02116771 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 6 0,000 4,799E-03 0,02114215 ! unconventional myosin complex GO:0016461 8 6 0,000 4,799E-03 0,02111665 ! tRNA transcription GO:0009304 7 7 0,000 5,596E-03 0,02459721 ! respiratory burst GO:0045730 7 7 0,000 5,596E-03 0,02456761 ! telencephalon cell migration GO:0022029 8 7 0,000 5,596E-03 0,02453808 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 5,596E-03 0,02450862 ! cation:chloride symporter activity GO:0015377 8 7 0,000 5,596E-03 0,02447923 ! RNA cap binding GO:0000339 8 7 0,000 5,596E-03 0,02444992 ! generation of neurons in the forebrain GO:0021872 8 7 0,000 5,596E-03 0,02442067 ! ephrin receptor binding GO:0046875 9 7 0,000 5,596E-03 0,0243915 ! male meiosis I GO:0007141 7 7 0,000 5,596E-03 0,02436239 ! synapsis GO:0007129 7 7 0,000 5,596E-03 0,02433335 GO:0070192|chromosome organization involved in meiosis, ! insulin receptor substrate binding GO:0043560 10 7 0,000 5,596E-03 0,02430438 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 5,596E-03 0,02427548 ! type I transforming growth factor beta receptor binding GO:0034713 8 7 0,000 5,596E-03 0,02424665 ! signal peptide processing GO:0006465 7 7 0,000 5,596E-03 0,02421789 ! regulation of cardiac muscle cell proliferation GO:0060043 8 7 0,000 5,596E-03 0,0241892 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 5,596E-03 0,02416057 ! macrophage chemotaxis GO:0048246 7 7 0,000 5,596E-03 0,02413201 ! Golgi cisterna membrane GO:0032580 7 7 0,000 5,596E-03 0,02410352 ! neurofilament cytoskeleton GO:0060053 8 7 0,000 5,596E-03 0,0240751 ! positive regulation of receptor-mediated endocytosis GO:0048260 7 7 0,000 5,596E-03 0,02404674 ! smoothened signaling pathway GO:0007224 8 7 0,000 5,596E-03 0,02401845 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 5,596E-03 0,02399023 ! oxidoreductase activity, oxidizing metal ions GO:0016722 7 7 0,000 5,596E-03 0,02396207 ! cytoplasmic microtubule GO:0005881 7 7 0,000 5,596E-03 0,02393398 ! Arp2/3 protein complex GO:0005885 8 7 0,000 5,596E-03 0,02390595 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 7 7 0,000 5,596E-03 0,02387799 ! ATPase binding GO:0051117 8 7 0,000 5,596E-03 0,0238501 ! positive regulation of isotype switching GO:0045830 7 7 0,000 5,596E-03 0,02382227 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 5,596E-03 0,0237945 ! positive regulation of gene expression, epigenetic GO:0045815 7 7 0,000 5,596E-03 0,0237668 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 7 0,000 5,596E-03 0,02373916 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 5,596E-03 0,02371159 ! thymic T cell selection GO:0045061 16 7 0,000 5,596E-03 0,02368409 ! transepithelial chloride transport GO:0030321 7 7 0,000 5,596E-03 0,02365664 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 5,596E-03 0,02362926 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 7 7 0,000 5,596E-03 0,02360194 ! negative regulation of survival gene product expression GO:0008634 9 7 0,000 5,596E-03 0,02357469 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 5,596E-03 0,0235475 ! melanocyte differentiation GO:0030318 8 7 0,000 5,596E-03 0,02352037 ! malate dehydrogenase activity GO:0016615 8 7 0,000 5,596E-03 0,0234933 ! mitochondrial respiratory chain complex assembly GO:0033108 7 7 0,000 5,596E-03 0,0234663 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! DNA secondary structure binding GO:0000217 16 7 0,000 5,596E-03 0,02343936 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 8 7 0,000 5,596E-03 0,02341248 ! regulation of peptidyl-serine phosphorylation GO:0033135 7 7 0,000 5,596E-03 0,02338566 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 5,596E-03 0,0233589 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 5,596E-03 0,02333221 GO:0021940|positive regulation of granule cell precursor proliferation, ! V(D)J recombination GO:0033151 8 7 0,000 5,596E-03 0,02330557 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 5,596E-03 0,023279 ! vascular endothelial growth factor receptor activity GO:0005021 12 7 0,000 5,596E-03 0,02325248 ! central nervous system neuron axonogenesis GO:0021955 8 7 0,000 5,596E-03 0,02322603 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 5,596E-03 0,02319964 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! response to tumor necrosis factor GO:0034612 8 7 0,000 5,596E-03 0,02317331 ! peptidoglycan metabolic process GO:0000270 9 7 0,000 5,596E-03 0,02314703 GO:0009253|peptidoglycan catabolic process, ! response to ATP GO:0033198 7 7 0,000 5,596E-03 0,02312082 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 8 7 0,000 5,596E-03 0,02309466 GO:0048500|signal recognition particle, ! stereocilium GO:0032420 10 7 0,000 5,596E-03 0,02306857 ! paraxial mesoderm morphogenesis GO:0048340 9 7 0,000 5,596E-03 0,02304253 ! melanosome organization GO:0032438 7 7 0,000 5,596E-03 0,02301655 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 8 7 0,000 5,596E-03 0,02299063 ! mesodermal cell differentiation GO:0048333 9 7 0,000 5,596E-03 0,02296477 GO:0001710|mesodermal cell fate commitment, ! positive regulation of neuroblast proliferation GO:0002052 7 7 0,000 5,596E-03 0,02293897 ! Rac protein signal transduction GO:0016601 7 7 0,000 5,596E-03 0,02291322 ! chondrocyte differentiation GO:0002062 7 7 0,000 5,596E-03 0,02288754 ! guanylate cyclase regulator activity GO:0030249 7 7 0,000 5,596E-03 0,02286191 GO:0010851|cyclase regulator activity, ! intestinal cholesterol absorption GO:0030299 9 7 0,000 5,596E-03 0,02283633 ! negative regulation of specific transcription from RNA polymerase II promoter GO:0010553 8 7 0,000 5,596E-03 0,02281082 ! positive regulation of mitotic cell cycle GO:0045931 7 7 0,000 5,596E-03 0,02278536 ! determination of anterior/posterior axis, embryo GO:0008595 10 7 0,000 5,596E-03 0,02275996 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 8 7 0,000 5,596E-03 0,02273461 ! regulation of vascular endothelial growth factor production GO:0010574 7 7 0,000 5,596E-03 0,02270932 ! Schwann cell differentiation GO:0014037 8 7 0,000 5,596E-03 0,02268409 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 9 7 0,000 5,596E-03 0,02265891 ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 5,596E-03 0,02263379 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 5,596E-03 0,02260873 ! vinculin binding GO:0017166 9 7 0,000 5,596E-03 0,02258372 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 5,596E-03 0,02255876 ! regulation of collagen metabolic process GO:0010712 8 7 0,000 5,596E-03 0,02253387 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 5,596E-03 0,02250902 ! negative regulation of gliogenesis GO:0014014 8 7 0,000 5,596E-03 0,02248423 GO:0045686|negative regulation of glial cell differentiation, ! translation termination factor activity GO:0008079 7 7 0,000 5,596E-03 0,0224595 GO:0003747|translation release factor activity, ! purine base biosynthetic process GO:0009113 8 7 0,000 5,596E-03 0,02243482 ! cardiac muscle cell development GO:0055013 8 7 0,000 5,596E-03 0,02241019 ! fibrinolysis GO:0042730 9 7 0,000 5,596E-03 0,02238562 ! response to tropane GO:0014073 10 7 0,000 5,596E-03 0,0223611 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 7 7 0,000 5,596E-03 0,02233663 GO:0051904|pigment granule transport, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 8 7 0,000 5,596E-03 0,02231222 ! glycosylceramide metabolic process GO:0006677 7 7 0,000 5,596E-03 0,02228786 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 7 7 0,000 5,596E-03 0,02226356 ! laminin-1 complex GO:0005606 7 7 0,000 5,596E-03 0,0222393 GO:0043256|laminin complex, ! regulation of chondrocyte differentiation GO:0032330 8 7 0,000 5,596E-03 0,02221511 ! positive regulation of immunoglobulin mediated immune response GO:0002891 7 7 0,000 5,596E-03 0,02219096 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of lipid transport GO:0032370 8 7 0,000 5,596E-03 0,02216686 ! regulation of cell division GO:0051302 7 7 0,000 5,596E-03 0,02214282 ! holo TFIIH complex GO:0005675 7 7 0,000 5,596E-03 0,02211883 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 7 0,000 5,596E-03 0,02209489 ! chitinase activity GO:0004568 7 7 0,000 5,596E-03 0,02207101 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 8 7 0,000 5,596E-03 0,02204717 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! U12-type spliceosomal complex GO:0005689 8 7 0,000 5,596E-03 0,02202339 ! regulation of respiratory burst GO:0060263 8 7 0,000 5,596E-03 0,02199966 ! prophase GO:0051324 8 7 0,000 5,596E-03 0,02197598 ! peptidyl-histidine modification GO:0018202 8 7 0,000 5,596E-03 0,02195235 ! centriolar satellite GO:0034451 10 7 0,000 5,596E-03 0,02192877 ! BBSome GO:0034464 7 7 0,000 5,596E-03 0,02190524 ! glycerophosphodiester phosphodiesterase activity GO:0008889 7 7 0,000 5,596E-03 0,02188176 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 5,596E-03 0,02185833 ! negative regulation of lymphocyte differentiation GO:0045620 8 7 0,000 5,596E-03 0,02183495 ! negative regulation of transmission of nerve impulse GO:0051970 7 7 0,000 5,596E-03 0,02181163 ! regulation of synaptic transmission, glutamatergic GO:0051966 8 7 0,000 5,596E-03 0,02178835 ! regulation of synaptogenesis GO:0051963 7 7 0,000 5,596E-03 0,02176512 ! serine family amino acid catabolic process GO:0009071 7 7 0,000 5,596E-03 0,02174194 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 5,596E-03 0,02171881 ! glycolipid catabolic process GO:0019377 7 7 0,000 5,596E-03 0,02169573 GO:0046479|glycosphingolipid catabolic process, ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 8 7 0,000 5,596E-03 0,0216727 ! circadian behavior GO:0048512 9 7 0,000 5,596E-03 0,02164972 ! dorsal/ventral axis specification GO:0009950 7 7 0,000 5,596E-03 0,02162678 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 7 0,000 5,596E-03 0,0216039 ! striatum development GO:0021756 7 7 0,000 5,596E-03 0,02158106 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 8 7 0,000 5,596E-03 0,02155827 ! triglyceride biosynthetic process GO:0019432 7 7 0,000 5,596E-03 0,02153553 ! cerebellar Purkinje cell layer development GO:0021680 7 7 0,000 5,596E-03 0,02151284 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 5,596E-03 0,02149019 ! dystroglycan complex GO:0016011 9 7 0,000 5,596E-03 0,02146759 ! negative regulation of calcium ion transport GO:0051926 7 7 0,000 5,596E-03 0,02144504 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 7 0,000 5,596E-03 0,02142254 ! peroxiredoxin activity GO:0051920 7 7 0,000 5,596E-03 0,02140009 ! muscle adaptation GO:0043500 7 7 0,000 5,596E-03 0,02137768 ! regulation of muscle adaptation GO:0043502 7 7 0,000 5,596E-03 0,02135532 ! diacylglycerol metabolic process GO:0046339 7 7 0,000 5,596E-03 0,021333 ! lysogeny GO:0030069 7 7 0,000 5,596E-03 0,02131073 GO:0019047|provirus integration, ! protein insertion into membrane GO:0051205 7 7 0,000 5,596E-03 0,02128851 ! sequestering of metal ion GO:0051238 9 7 0,000 5,596E-03 0,02126634 ! membrane attack complex GO:0005579 7 7 0,000 5,596E-03 0,02124421 ! fibrinogen complex GO:0005577 7 7 0,000 5,596E-03 0,02122212 ! metallo-sulfur cluster assembly GO:0031163 9 7 0,000 5,596E-03 0,02120008 GO:0016226|iron-sulfur cluster assembly, ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 7 0,000 5,596E-03 0,02117809 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 7 0,000 5,596E-03 0,02115615 ! GABA receptor binding GO:0050811 8 7 0,000 5,596E-03 0,02113425 ! sheet-forming collagen GO:0030935 7 7 0,000 5,596E-03 0,02111239 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 8 7 0,000 5,596E-03 0,02109058 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 8 7 0,000 5,596E-03 0,02106882 ! sphingomyelin phosphodiesterase activity GO:0004767 9 7 0,000 5,596E-03 0,02104709 ! regulation of epithelial cell differentiation GO:0030856 7 7 0,000 5,596E-03 0,02102542 ! 7S RNA binding GO:0008312 8 7 0,000 5,596E-03 0,02100379 ! positive regulation of lipid catabolic process GO:0050996 7 7 0,000 5,596E-03 0,0209822 ! protein phosphorylated amino acid binding GO:0045309 9 7 0,000 5,596E-03 0,02096066 ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 8 7 0,000 5,596E-03 0,02093916 ! regulation of long-term neuronal synaptic plasticity GO:0048169 17 7 0,000 5,596E-03 0,02091771 ! Golgi to endosome transport GO:0006895 8 7 0,000 5,596E-03 0,0208963 ! glucocorticoid receptor signaling pathway GO:0042921 7 7 0,000 5,596E-03 0,02087493 GO:0031958|corticosteroid receptor signaling pathway, ! succinate metabolic process GO:0006105 7 7 0,000 5,596E-03 0,02085361 ! fibril GO:0043205 7 7 0,000 5,596E-03 0,02083233 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 5,596E-03 0,02081109 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 5,596E-03 0,0207899 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 7 0,000 5,596E-03 0,02076875 ! sensory perception of bitter taste GO:0050913 7 7 0,000 5,596E-03 0,02074764 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 5,596E-03 0,02072658 ! posttranscriptional gene silencing by RNA GO:0035194 9 7 0,000 5,596E-03 0,02070556 GO:0016441|posttranscriptional gene silencing, ! cell division site part GO:0032155 9 7 0,000 5,596E-03 0,02068458 GO:0032153|cell division site, ! laminin binding GO:0043236 7 7 0,000 5,596E-03 0,02066365 ! equilibrioception GO:0050957 10 7 0,000 5,596E-03 0,02064275 ! G-protein coupled receptor kinase activity GO:0004703 9 7 0,000 5,596E-03 0,0206219 ! titin binding GO:0031432 7 7 0,000 5,596E-03 0,02060109 ! chemosensory behavior GO:0007635 9 7 0,000 5,596E-03 0,02058032 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 5,596E-03 0,0205596 GO:0032107|regulation of response to nutrient levels, ! plasma lipoprotein particle assembly GO:0034377 7 7 0,000 5,596E-03 0,02053892 ! cobalamin binding GO:0031419 7 7 0,000 5,596E-03 0,02051827 ! sodium:phosphate symporter activity GO:0005436 8 7 0,000 5,596E-03 0,02049767 ! response to axon injury GO:0048678 9 7 0,000 5,596E-03 0,02047711 ! regulation of activin receptor signaling pathway GO:0032925 7 7 0,000 5,596E-03 0,0204566 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 5,596E-03 0,02043612 ! F-actin capping protein complex GO:0008290 8 7 0,000 5,596E-03 0,02041568 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 5,596E-03 0,02039529 ! nerve growth factor receptor signaling pathway GO:0048011 8 7 0,000 5,596E-03 0,02037493 ! cAMP-dependent protein kinase activity GO:0004691 7 7 0,000 5,596E-03 0,02035462 ! senescence GO:0010149 8 7 0,000 5,596E-03 0,02033434 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 10 7 0,000 5,596E-03 0,02031411 ! nuclear localization sequence binding GO:0008139 8 7 0,000 5,596E-03 0,02029392 ! galactose metabolic process GO:0006012 8 7 0,000 5,596E-03 0,02027377 ! vesicle fusion GO:0006906 8 7 0,000 5,596E-03 0,02025365 ! maintenance of protein location in nucleus GO:0051457 7 7 0,000 5,596E-03 0,02023358 ! intracellular pH reduction GO:0051452 7 7 0,000 5,596E-03 0,02021355 ! glycerol ether catabolic process GO:0044269 16 7 0,000 5,596E-03 0,02019355 GO:0046461|neutral lipid catabolic process, GO:0046464|acylglycerol catabolic process, ! neurotransmitter catabolic process GO:0042135 9 7 0,000 5,596E-03 0,0201736 ! ruffle organization GO:0031529 9 7 0,000 5,596E-03 0,02015368 ! nucleoside transport GO:0015858 8 7 0,000 5,596E-03 0,02013381 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 5,596E-03 0,02011397 ! inclusion body GO:0016234 7 7 0,000 5,596E-03 0,02009418 ! Cajal body GO:0015030 7 7 0,000 5,596E-03 0,02007442 ! H4/H2A histone acetyltransferase complex GO:0043189 9 7 0,000 5,596E-03 0,0200547 ! rRNA modification GO:0000154 7 7 0,000 5,596E-03 0,02003502 ! PcG protein complex GO:0031519 7 7 0,000 5,596E-03 0,02001537 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 5,596E-03 0,01999577 ! NAD-dependent protein deacetylase activity GO:0034979 7 7 0,000 5,596E-03 0,01997621 GO:0017136|NAD-dependent histone deacetylase activity, ! spindle checkpoint GO:0031577 7 7 0,000 5,596E-03 0,01995668 ! apolipoprotein binding GO:0034185 9 7 0,000 5,596E-03 0,01993719 ! G1 DNA damage checkpoint GO:0031571 7 7 0,000 5,596E-03 0,01991774 ! segment specification GO:0007379 9 7 0,000 5,596E-03 0,01989833 ! pronucleus GO:0045120 25 7 0,000 5,596E-03 0,01987895 ! bile acid:sodium symporter activity GO:0008508 9 7 0,000 5,596E-03 0,01985961 ! Rac GTPase activator activity GO:0030675 9 7 0,000 5,596E-03 0,01984031 ! regulation of DNA repair GO:0006282 19 7 0,000 5,596E-03 0,01982105 ! DNA topological change GO:0006265 7 7 0,000 5,596E-03 0,01980183 ! DNA ligation GO:0006266 8 7 0,000 5,596E-03 0,01978264 ! hair follicle maturation GO:0048820 8 7 0,000 5,596E-03 0,01976349 ! renal water homeostasis GO:0003091 7 7 0,000 5,596E-03 0,01974437 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 5,596E-03 0,0197253 ! positive regulation of interleukin-6 production GO:0032755 7 7 0,000 5,596E-03 0,01970626 ! interleukin-1 receptor activity GO:0004908 8 7 0,000 5,596E-03 0,01968725 ! positive regulation of tumor necrosis factor production GO:0032760 7 7 0,000 5,596E-03 0,01966829 ! positive regulation of monooxygenase activity GO:0032770 7 7 0,000 5,596E-03 0,01964936 ! inositol trisphosphate 3-kinase activity GO:0008440 8 7 0,000 5,596E-03 0,01963046 ! phosphofructokinase activity GO:0008443 7 7 0,000 5,596E-03 0,01961161 ! gap junction channel activity GO:0005243 8 7 0,000 5,596E-03 0,01959278 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 10 7 0,000 5,596E-03 0,019574 ! histone methylation GO:0016571 7 7 0,000 5,596E-03 0,01955525 ! positive regulation of interferon-gamma production GO:0032729 7 7 0,000 5,596E-03 0,01953654 ! negative regulation of tumor necrosis factor production GO:0032720 9 7 0,000 5,596E-03 0,01951786 ! mitochondrion morphogenesis GO:0070584 9 7 0,000 5,596E-03 0,01949922 ! muscle cell proliferation GO:0033002 8 7 0,000 5,596E-03 0,01948061 ! transcription termination GO:0006353 9 7 0,000 5,596E-03 0,01946204 ! regulation of transcription from RNA polymerase III promoter GO:0006359 16 7 0,000 5,596E-03 0,01944351 ! sodium:amino acid symporter activity GO:0005283 7 7 0,000 5,596E-03 0,01942501 ! cytidylyltransferase activity GO:0070567 8 7 0,000 5,596E-03 0,01940654 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 5,596E-03 0,01938811 ! ATP-dependent peptidase activity GO:0004176 7 7 0,000 5,596E-03 0,01936972 ! salivary gland development GO:0007431 7 7 0,000 5,596E-03 0,01935136 ! glucosidase activity GO:0015926 8 7 0,000 5,596E-03 0,01933303 ! NuRD complex GO:0016581 8 7 0,000 5,596E-03 0,01931474 ! negative regulation of nuclear division GO:0051784 7 7 0,000 5,596E-03 0,01929649 GO:0045839|negative regulation of mitosis, ! ATP-gated cation channel activity GO:0004931 9 7 0,000 5,596E-03 0,01927826 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 7 7 0,000 5,596E-03 0,01926008 ! response to redox state GO:0051775 8 7 0,000 5,596E-03 0,01924192 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 5,596E-03 0,01922381 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 5,596E-03 0,01920572 ! procollagen-proline dioxygenase activity GO:0019798 7 7 0,000 5,596E-03 0,01918767 ! actin monomer binding GO:0003785 7 7 0,000 5,596E-03 0,01916965 ! protein prenyltransferase activity GO:0008318 8 7 0,000 5,596E-03 0,01915167 ! endosome to lysosome transport GO:0008333 7 7 0,000 5,596E-03 0,01913372 ! regulation of Rac protein signal transduction GO:0035020 17 7 0,000 5,596E-03 0,01911581 ! germ cell migration GO:0008354 7 7 0,000 5,596E-03 0,01909792 ! fibroblast growth factor receptor binding GO:0005104 8 7 0,000 5,596E-03 0,01908008 ! negative regulation of organic acid transport GO:0032891 8 7 0,000 5,596E-03 0,01906226 ! CoA-ligase activity GO:0016405 8 7 0,000 5,596E-03 0,01904448 ! positive regulation of NF-kappaB import into nucleus GO:0042346 8 7 0,000 5,596E-03 0,01902673 ! interferon-alpha/beta receptor binding GO:0005132 7 7 0,000 5,596E-03 0,01900901 ! embryonic heart tube development GO:0035050 8 7 0,000 5,596E-03 0,01899133 ! dihydropyridine-sensitive calcium channel activity GO:0015270 10 7 0,000 5,596E-03 0,01897368 ! kainate selective glutamate receptor activity GO:0015277 8 7 0,000 5,596E-03 0,01895606 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 5,596E-03 0,01893848 ! amiloride-sensitive sodium channel activity GO:0015280 7 7 0,000 5,596E-03 0,01892093 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 5,596E-03 0,01890341 ! adenylate kinase activity GO:0004017 8 7 0,000 5,596E-03 0,01888592 ! negative regulation of immune effector process GO:0002698 13 7 0,000 5,596E-03 0,01886847 ! C-X-C chemokine receptor activity GO:0016494 7 7 0,000 5,596E-03 0,01885105 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 7 7 0,000 5,596E-03 0,01883365 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 10 8 0,000 6,393E-03 0,0214963 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 9 8 0,000 6,393E-03 0,02147651 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 8 0,000 6,393E-03 0,02145675 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 6,393E-03 0,02143703 ! negative regulation of lipid biosynthetic process GO:0051055 18 8 0,000 6,393E-03 0,02141734 ! regulation of cellular amine metabolic process GO:0033238 10 8 0,000 6,393E-03 0,02139769 ! proteasome regulatory particle GO:0005838 8 8 0,000 6,393E-03 0,02137808 ! SMAD protein complex assembly GO:0007183 10 8 0,000 6,393E-03 0,0213585 ! regulation of smooth muscle cell migration GO:0014910 11 8 0,000 6,393E-03 0,02133896 ! protein self-association GO:0043621 8 8 0,000 6,393E-03 0,02131946 ! glycine hydroxymethyltransferase activity GO:0004372 9 8 0,000 6,393E-03 0,02129999 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 8 0,000 6,393E-03 0,02128055 ! neurotransmitter uptake GO:0001504 8 8 0,000 6,393E-03 0,02126116 ! regulation of activated T cell proliferation GO:0046006 9 8 0,000 6,393E-03 0,02124179 ! guanylate cyclase activity GO:0004383 9 8 0,000 6,393E-03 0,02122246 ! troponin complex GO:0005861 8 8 0,000 6,393E-03 0,02120317 ! eukaryotic translation initiation factor 3 complex GO:0005852 8 8 0,000 6,393E-03 0,02118391 ! tachykinin receptor signaling pathway GO:0007217 8 8 0,000 6,393E-03 0,02116469 ! negative regulation of muscle cell differentiation GO:0051148 10 8 0,000 6,393E-03 0,0211455 ! microtubule bundle formation GO:0001578 8 8 0,000 6,393E-03 0,02112635 ! middle ear morphogenesis GO:0042474 10 8 0,000 6,393E-03 0,02110723 ! ganglioside metabolic process GO:0001573 8 8 0,000 6,393E-03 0,02108814 ! regulation of mesenchymal cell proliferation GO:0010464 9 8 0,000 6,393E-03 0,02106909 GO:0002053|positive regulation of mesenchymal cell proliferation, ! ovulation from ovarian follicle GO:0001542 8 8 0,000 6,393E-03 0,02105008 ! ciliary or flagellar motility GO:0001539 8 8 0,000 6,393E-03 0,0210311 ! pathogenesis GO:0009405 8 8 0,000 6,393E-03 0,02101215 ! pH reduction GO:0045851 9 8 0,000 6,393E-03 0,02099324 ! small protein activating enzyme activity GO:0008641 10 8 0,000 6,393E-03 0,02097436 ! ribonucleoside triphosphate catabolic process GO:0009203 8 8 0,000 6,393E-03 0,02095551 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 6,393E-03 0,0209367 ! hemoglobin metabolic process GO:0020027 8 8 0,000 6,393E-03 0,02091793 ! arginine catabolic process GO:0006527 9 8 0,000 6,393E-03 0,02089918 ! T-tubule GO:0030315 9 8 0,000 6,393E-03 0,02088047 ! regulation of defense response to virus by virus GO:0050690 17 8 0,000 6,393E-03 0,0208618 ! histidine catabolic process GO:0006548 8 8 0,000 6,393E-03 0,02084315 GO:0009077|histidine family amino acid catabolic process, ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 6,393E-03 0,02082454 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 8 0,000 6,393E-03 0,02080597 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 10 8 0,000 6,393E-03 0,02078742 ! proline metabolic process GO:0006560 10 8 0,000 6,393E-03 0,02076891 ! L-serine metabolic process GO:0006563 9 8 0,000 6,393E-03 0,02075043 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 8 8 0,000 6,393E-03 0,02073199 ! melanosome membrane GO:0033162 9 8 0,000 6,393E-03 0,02071358 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 6,393E-03 0,0206952 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 8 8 0,000 6,393E-03 0,02067685 ! pericentriolar material GO:0000242 9 8 0,000 6,393E-03 0,02065854 ! reverse cholesterol transport GO:0043691 8 8 0,000 6,393E-03 0,02064025 ! tumor necrosis factor receptor activity GO:0005031 8 8 0,000 6,393E-03 0,020622 ! melanin metabolic process GO:0006582 10 8 0,000 6,393E-03 0,02060379 ! proton-transporting V-type ATPase, V1 domain GO:0033180 8 8 0,000 6,393E-03 0,0205856 ! phasic smooth muscle contraction GO:0014821 9 8 0,000 6,393E-03 0,02056745 ! Golgi lumen GO:0005796 8 8 0,000 6,393E-03 0,02054933 ! positive regulation of endothelial cell migration GO:0010595 9 8 0,000 6,393E-03 0,02053124 ! regulation of Cdc42 protein signal transduction GO:0032489 9 8 0,000 6,393E-03 0,02051318 GO:0043088|regulation of Cdc42 GTPase activity, ! methyltransferase complex GO:0034708 8 8 0,000 6,393E-03 0,02049516 GO:0035097|histone methyltransferase complex, ! paraxial mesoderm development GO:0048339 10 8 0,000 6,393E-03 0,02047716 ! stereocilium bundle GO:0032421 11 8 0,000 6,393E-03 0,0204592 ! forebrain cell migration GO:0021885 9 8 0,000 6,393E-03 0,02044127 ! peptidyl-threonine phosphorylation GO:0018107 11 8 0,000 6,393E-03 0,02042337 ! osteoblast development GO:0002076 11 8 0,000 6,393E-03 0,0204055 ! retinoic acid metabolic process GO:0042573 8 8 0,000 6,393E-03 0,02038766 ! retinol metabolic process GO:0042572 8 8 0,000 6,393E-03 0,02036986 ! negative regulation of muscle contraction GO:0045932 10 8 0,000 6,393E-03 0,02035208 ! structural constituent of epidermis GO:0030280 9 8 0,000 6,393E-03 0,02033434 ! clathrin binding GO:0030276 10 8 0,000 6,393E-03 0,02031663 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 9 8 0,000 6,393E-03 0,02029894 ! chondroitin sulfate biosynthetic process GO:0030206 9 8 0,000 6,393E-03 0,02028129 GO:0030204|chondroitin sulfate metabolic process, ! sodium:dicarboxylate symporter activity GO:0017153 9 8 0,000 6,393E-03 0,02026367 ! motor axon guidance GO:0008045 8 8 0,000 6,393E-03 0,02024608 ! protein targeting to vacuole GO:0006623 8 8 0,000 6,393E-03 0,02022852 ! negative regulation of axonogenesis GO:0050771 12 8 0,000 6,393E-03 0,02021099 ! peptidyl-asparagine modification GO:0018196 8 8 0,000 6,393E-03 0,0201935 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! melanosome localization GO:0032400 8 8 0,000 6,393E-03 0,02017603 GO:0032401|establishment of melanosome localization, GO:0051875|pigment granule localization, GO:0051905|establishment of pigment granule localization, ! mismatch repair complex binding GO:0032404 10 8 0,000 6,393E-03 0,02015859 ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 6,393E-03 0,02014118 ! protein-lipid complex assembly GO:0065005 8 8 0,000 6,393E-03 0,0201238 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 9 8 0,000 6,393E-03 0,02010645 ! phosphoinositide 3-kinase cascade GO:0014065 8 8 0,000 6,393E-03 0,02008914 ! regulation of dopamine secretion GO:0014059 9 8 0,000 6,393E-03 0,02007185 ! regulation of protein kinase B signaling cascade GO:0051896 9 8 0,000 6,393E-03 0,02005459 ! cranial nerve morphogenesis GO:0021602 9 8 0,000 6,393E-03 0,02003736 ! subpallium development GO:0021544 8 8 0,000 6,393E-03 0,02002016 ! icosanoid secretion GO:0032309 10 8 0,000 6,393E-03 0,02000299 GO:0050482|arachidonic acid secretion, ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 6,393E-03 0,01998585 ! regulation of DNA replication initiation GO:0030174 8 8 0,000 6,393E-03 0,01996874 ! negative regulation of cytokine secretion GO:0050710 10 8 0,000 6,393E-03 0,01995166 ! dolichyl-diphosphooligosaccharide-protein glycotransferase activity GO:0004579 8 8 0,000 6,393E-03 0,0199346 ! exodeoxyribonuclease activity GO:0004529 18 8 0,000 6,393E-03 0,01991758 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! ER to Golgi transport vesicle GO:0030134 9 8 0,000 6,393E-03 0,01990059 ! nucleotide diphosphatase activity GO:0004551 9 8 0,000 6,393E-03 0,01988362 ! regulation of myoblast differentiation GO:0045661 9 8 0,000 6,393E-03 0,01986668 ! ubiquinone metabolic process GO:0006743 9 8 0,000 6,393E-03 0,01984978 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! neuromuscular process controlling posture GO:0050884 8 8 0,000 6,393E-03 0,0198329 ! multicellular organismal water homeostasis GO:0050891 8 8 0,000 6,393E-03 0,01981605 ! branched chain family amino acid catabolic process GO:0009083 9 8 0,000 6,393E-03 0,01979923 ! Wnt receptor activity GO:0042813 11 8 0,000 6,393E-03 0,01978243 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 6,393E-03 0,01976567 ! leukocyte mediated cytotoxicity GO:0001909 10 8 0,000 6,393E-03 0,01974893 ! detection of calcium ion GO:0005513 9 8 0,000 6,393E-03 0,01973222 ! negative regulation of glucose import GO:0046325 9 8 0,000 6,393E-03 0,01971554 ! blastocyst growth GO:0001832 8 8 0,000 6,393E-03 0,01969889 ! regulation of fibrinolysis GO:0051917 8 8 0,000 6,393E-03 0,01968227 ! negative regulation of telomere maintenance GO:0032205 9 8 0,000 6,393E-03 0,01966567 ! cerebellar cortex formation GO:0021697 9 8 0,000 6,393E-03 0,0196491 ! complement binding GO:0001848 11 8 0,000 6,393E-03 0,01963257 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 8 0,000 6,393E-03 0,01961605 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 8 0,000 6,393E-03 0,01959957 ! amino sugar catabolic process GO:0046348 8 8 0,000 6,393E-03 0,01958311 GO:0006043|glucosamine catabolic process, ! FK506 binding GO:0005528 9 8 0,000 6,393E-03 0,01956668 GO:0005527|macrolide binding, ! dipeptidase activity GO:0016805 8 8 0,000 6,393E-03 0,01955028 ! positive regulation of amine transport GO:0051954 9 8 0,000 6,393E-03 0,01953391 ! release of sequestered calcium ion into cytosol GO:0051209 13 8 0,000 6,393E-03 0,01951756 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, ! B cell receptor signaling pathway GO:0050853 13 8 0,000 6,393E-03 0,01950124 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 6,393E-03 0,01948495 ! Golgi transport complex GO:0017119 8 8 0,000 6,393E-03 0,01946869 ! positive regulation of protein ubiquitination GO:0031398 17 8 0,000 6,393E-03 0,01945245 ! GDP binding GO:0019003 9 8 0,000 6,393E-03 0,01943624 ! positive regulation of glucose metabolic process GO:0010907 8 8 0,000 6,393E-03 0,01942006 ! prostate gland development GO:0030850 17 8 0,000 6,393E-03 0,0194039 ! DNA synthesis during DNA repair GO:0000731 19 8 0,000 6,393E-03 0,01938777 ! nitric-oxide synthase binding GO:0050998 9 8 0,000 6,393E-03 0,01937167 ! phosphate transport GO:0006817 9 8 0,000 6,393E-03 0,01935559 ! cellular copper ion homeostasis GO:0006878 8 8 0,000 6,393E-03 0,01933954 ! oligopeptide transport GO:0006857 8 8 0,000 6,393E-03 0,01932352 GO:0015198|oligopeptide transporter activity, ! pigment cell differentiation GO:0050931 9 8 0,000 6,393E-03 0,01930752 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 6,393E-03 0,01929155 ! oligosaccharyltransferase complex GO:0008250 8 8 0,000 6,393E-03 0,01927561 ! lipoprotein transport GO:0042953 9 8 0,000 6,393E-03 0,01925969 ! estrogen metabolic process GO:0008210 8 8 0,000 6,393E-03 0,0192438 ! nucleocytoplasmic transporter activity GO:0005487 8 8 0,000 6,393E-03 0,01922794 ! glucocorticoid metabolic process GO:0008211 8 8 0,000 6,393E-03 0,0192121 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 8 8 0,000 6,393E-03 0,01919629 ! T-helper 1 type immune response GO:0042088 8 8 0,000 6,393E-03 0,0191805 ! amyloid precursor protein catabolic process GO:0042987 10 8 0,000 6,393E-03 0,01916474 ! response to amphetamine GO:0001975 11 8 0,000 6,393E-03 0,019149 ! mechanosensory behavior GO:0007638 8 8 0,000 6,393E-03 0,0191333 ! detection of chemical stimulus involved in sensory perception GO:0050907 8 8 0,000 6,393E-03 0,01911761 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 6,393E-03 0,01910196 ! C-X-C chemokine binding GO:0019958 8 8 0,000 6,393E-03 0,01908632 ! two-component signal transduction system (phosphorelay) GO:0000160 9 8 0,000 6,393E-03 0,01907072 ! glycerolipid catabolic process GO:0046503 17 8 0,000 6,393E-03 0,01905514 ! spinal cord dorsal/ventral patterning GO:0021513 10 8 0,000 6,393E-03 0,01903958 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 9 8 0,000 6,393E-03 0,01902405 ! inositol phosphate-mediated signaling GO:0048016 9 8 0,000 6,393E-03 0,01900855 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 6,393E-03 0,01899307 ! pigment granule organization GO:0048753 9 8 0,000 6,393E-03 0,01897761 ! GTP-dependent protein binding GO:0030742 11 8 0,000 6,393E-03 0,01896218 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 6,393E-03 0,01894678 ! regulation of interleukin-8 biosynthetic process GO:0045414 9 8 0,000 6,393E-03 0,0189314 ! regulation of pigmentation during development GO:0048070 11 8 0,000 6,393E-03 0,01891605 ! macrophage activation GO:0042116 8 8 0,000 6,393E-03 0,01890072 ! poly(A) RNA binding GO:0008143 8 8 0,000 6,393E-03 0,01888541 ! positive regulation of insulin secretion GO:0032024 10 8 0,000 6,393E-03 0,01887014 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 18 8 0,000 6,393E-03 0,01885488 ! asymmetric protein localization GO:0008105 9 8 0,000 6,393E-03 0,01883965 ! nucleotide-sugar transmembrane transporter activity GO:0005338 8 8 0,000 6,393E-03 0,01882444 ! neurotrophin binding GO:0043121 10 8 0,000 6,393E-03 0,01880926 ! nucleoside transmembrane transporter activity GO:0005337 9 8 0,000 6,393E-03 0,01879411 ! positive regulation of multicellular organismal metabolic process GO:0044253 9 8 0,000 6,393E-03 0,01877898 ! phagocytosis, engulfment GO:0006911 10 8 0,000 6,393E-03 0,01876387 ! UDP-glucosyltransferase activity GO:0035251 8 8 0,000 6,393E-03 0,01874878 ! neurotransmitter biosynthetic process GO:0042136 9 8 0,000 6,393E-03 0,01873372 ! UV protection GO:0009650 9 8 0,000 6,393E-03 0,01871869 ! peptidyl-proline dioxygenase activity GO:0031543 8 8 0,000 6,393E-03 0,01870368 ! eukaryotic translation initiation factor 4F complex GO:0016281 10 8 0,000 6,393E-03 0,01868869 ! glutathione peroxidase activity GO:0004602 17 8 0,000 6,393E-03 0,01867373 ! acyl-CoA thioesterase activity GO:0016291 10 8 0,000 6,393E-03 0,01865879 ! ATP-binding cassette (ABC) transporter complex GO:0043190 8 8 0,000 6,393E-03 0,01864387 ! ferric iron binding GO:0008199 9 8 0,000 6,393E-03 0,01862898 ! response to UV-B GO:0010224 10 8 0,000 6,393E-03 0,01861412 ! intermediate filament organization GO:0045109 8 8 0,000 6,393E-03 0,01859927 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 6,393E-03 0,01858445 ! cellular extravasation GO:0045123 9 8 0,000 6,393E-03 0,01856966 ! skeletal muscle contraction GO:0003009 8 8 0,000 6,393E-03 0,01855488 ! positive regulation of cytokine production during immune response GO:0002720 8 8 0,000 6,393E-03 0,01854013 ! regulation of fatty acid biosynthetic process GO:0042304 17 8 0,000 6,393E-03 0,01852541 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 6,393E-03 0,0185107 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 6,393E-03 0,01849602 ! positive regulation of systemic arterial blood pressure GO:0003084 10 8 0,000 6,393E-03 0,01848137 ! negative regulation of systemic arterial blood pressure GO:0003085 9 8 0,000 6,393E-03 0,01846674 ! respiratory chain complex IV assembly GO:0008535 8 8 0,000 6,393E-03 0,01845213 ! erythrocyte development GO:0048821 9 8 0,000 6,393E-03 0,01843754 ! regulation of interleukin-10 production GO:0032653 8 8 0,000 6,393E-03 0,01842298 ! ribosome assembly GO:0042255 8 8 0,000 6,393E-03 0,01840844 ! postreplication repair GO:0006301 19 8 0,000 6,393E-03 0,01839392 ! gamma-tubulin binding GO:0043015 8 8 0,000 6,393E-03 0,01837942 ! NADPH oxidase complex GO:0043020 8 8 0,000 6,393E-03 0,01836495 ! mRNA cleavage GO:0006379 9 8 0,000 6,393E-03 0,0183505 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 9 8 0,000 6,393E-03 0,01833607 ! opioid receptor activity GO:0004985 8 8 0,000 6,393E-03 0,01832167 ! zymogen activation GO:0031638 9 8 0,000 6,393E-03 0,01830729 ! coenzyme A metabolic process GO:0015936 8 8 0,000 6,393E-03 0,01829293 ! cellular metabolic compound salvage GO:0043094 11 8 0,000 6,393E-03 0,0182786 ! costamere GO:0043034 8 8 0,000 6,393E-03 0,01826428 ! inositol trisphosphate kinase activity GO:0051766 9 8 0,000 6,393E-03 0,01824999 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 6,393E-03 0,01823572 ! sarcomere organization GO:0045214 9 8 0,000 6,393E-03 0,01822147 ! wide pore channel activity GO:0022829 9 8 0,000 6,393E-03 0,01820725 ! ligand-regulated transcription factor activity GO:0003706 10 8 0,000 6,393E-03 0,01819305 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 6,393E-03 0,01817887 ! hormone catabolic process GO:0042447 9 8 0,000 6,393E-03 0,01816471 ! mRNA 3'-UTR binding GO:0003730 9 8 0,000 6,393E-03 0,01815057 ! cGMP biosynthetic process GO:0006182 9 8 0,000 6,393E-03 0,01813646 ! lysozyme activity GO:0003796 10 8 0,000 6,393E-03 0,01812237 ! death receptor binding GO:0005123 8 8 0,000 6,393E-03 0,0181083 ! protein modification by small protein removal GO:0070646 9 8 0,000 6,393E-03 0,01809425 ! adult feeding behavior GO:0008343 9 8 0,000 6,393E-03 0,01808022 ! microtubule basal body GO:0005932 8 8 0,000 6,393E-03 0,01806622 ! pyrimidine nucleotide catabolic process GO:0006244 8 8 0,000 6,393E-03 0,01805223 ! interleukin-1 receptor binding GO:0005149 9 8 0,000 6,393E-03 0,01803827 ! calcium-release channel activity GO:0015278 8 8 0,000 6,393E-03 0,01802433 ! positive regulation of smooth muscle contraction GO:0045987 9 8 0,000 6,393E-03 0,01801041 ! behavioral response to nicotine GO:0035095 9 8 0,000 6,393E-03 0,01799652 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 6,393E-03 0,01798264 ! adenosine deaminase activity GO:0004000 8 8 0,000 6,393E-03 0,01796879 ! NAD biosynthetic process GO:0009435 9 8 0,000 6,393E-03 0,01795496 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 9 0,000 7,19E-03 0,02017624 ! positive regulation of glycogen biosynthetic process GO:0045725 9 9 0,000 7,19E-03 0,02016074 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 7,19E-03 0,02014525 ! sodium:hydrogen antiporter activity GO:0015385 9 9 0,000 7,19E-03 0,02012979 GO:0005451|monovalent cation:hydrogen antiporter activity, ! cGMP metabolic process GO:0046068 10 9 0,000 7,19E-03 0,02011435 ! myotube differentiation GO:0014902 9 9 0,000 7,19E-03 0,02009894 ! folic acid and derivative biosynthetic process GO:0009396 9 9 0,000 7,19E-03 0,02008355 ! N-glycan processing GO:0006491 10 9 0,000 7,19E-03 0,02006818 ! regulation of epidermal growth factor receptor activity GO:0007176 11 9 0,000 7,19E-03 0,02005284 ! actin-myosin filament sliding GO:0033275 11 9 0,000 7,19E-03 0,02003752 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! axon part GO:0033267 12 9 0,000 7,19E-03 0,02002223 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 10 9 0,000 7,19E-03 0,02000695 ! RNA methylation GO:0001510 9 9 0,000 7,19E-03 0,01999171 ! prostaglandin biosynthetic process GO:0001516 9 9 0,000 7,19E-03 0,01997648 GO:0046457|prostanoid biosynthetic process, ! negative regulation of gene-specific transcription GO:0032582 10 9 0,000 7,19E-03 0,01996128 ! artery development GO:0060840 9 9 0,000 7,19E-03 0,0199461 GO:0048844|artery morphogenesis, ! axonemal dynein complex GO:0005858 9 9 0,000 7,19E-03 0,01993094 ! regulation of postsynaptic membrane potential GO:0060078 11 9 0,000 7,19E-03 0,01991581 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 9 9 0,000 7,19E-03 0,0199007 ! auditory receptor cell differentiation GO:0042491 10 9 0,000 7,19E-03 0,01988561 ! positive regulation of heart contraction GO:0045823 11 9 0,000 7,19E-03 0,01987054 ! lipopolysaccharide binding GO:0001530 9 9 0,000 7,19E-03 0,0198555 ! regulated secretory pathway GO:0045055 10 9 0,000 7,19E-03 0,01984048 ! estrogen receptor binding GO:0030331 9 9 0,000 7,19E-03 0,01982549 ! inner mitochondrial membrane organization GO:0007007 10 9 0,000 7,19E-03 0,01981051 ! telomere maintenance via telomerase GO:0007004 20 9 0,000 7,19E-03 0,01979556 GO:0006278|RNA-dependent DNA replication, ! L-phenylalanine metabolic process GO:0006558 9 9 0,000 7,19E-03 0,01978063 GO:0006559|L-phenylalanine catabolic process, ! indolalkylamine metabolic process GO:0006586 9 9 0,000 7,19E-03 0,01976573 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! urea metabolic process GO:0019627 19 9 0,000 7,19E-03 0,01975084 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! smooth endoplasmic reticulum GO:0005790 11 9 0,000 7,19E-03 0,01973598 ! autophagic vacuole GO:0005776 11 9 0,000 7,19E-03 0,01972114 ! Rac GTPase binding GO:0048365 10 9 0,000 7,19E-03 0,01970632 ! response to dietary excess GO:0002021 9 9 0,000 7,19E-03 0,01969153 ! regulation of sodium ion transport GO:0002028 10 9 0,000 7,19E-03 0,01967676 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 7,19E-03 0,01966201 ! lens development in camera-type eye GO:0002088 9 9 0,000 7,19E-03 0,01964728 ! male sex determination GO:0030238 9 9 0,000 7,19E-03 0,01963257 ! positive regulation of vasodilation GO:0045909 19 9 0,000 7,19E-03 0,01961789 ! positive regulation of muscle contraction GO:0045933 11 9 0,000 7,19E-03 0,01960323 ! regulation of smoothened signaling pathway GO:0008589 11 9 0,000 7,19E-03 0,01958859 ! male germ cell nucleus GO:0001673 11 9 0,000 7,19E-03 0,01957397 ! negative regulation of foam cell differentiation GO:0010745 12 9 0,000 7,19E-03 0,01955937 ! copper ion homeostasis GO:0055070 9 9 0,000 7,19E-03 0,0195448 ! protein heterooligomerization GO:0051291 10 9 0,000 7,19E-03 0,01953024 ! spectrin GO:0008091 9 9 0,000 7,19E-03 0,01951571 ! cardiac muscle cell differentiation GO:0055007 12 9 0,000 7,19E-03 0,0195012 ! purine nucleoside triphosphate catabolic process GO:0009146 9 9 0,000 7,19E-03 0,01948671 ! synaptic vesicle exocytosis GO:0016079 10 9 0,000 7,19E-03 0,01947225 ! regulation of B cell differentiation GO:0045577 10 9 0,000 7,19E-03 0,0194578 ! cell differentiation in hindbrain GO:0021533 10 9 0,000 7,19E-03 0,01944338 ! neural tube patterning GO:0021532 10 9 0,000 7,19E-03 0,01942898 ! fucose catabolic process GO:0019317 10 9 0,000 7,19E-03 0,01941459 GO:0042355|L-fucose catabolic process, ! retinal ganglion cell axon guidance GO:0031290 10 9 0,000 7,19E-03 0,01940023 ! regulation of hormone metabolic process GO:0032350 12 9 0,000 7,19E-03 0,0193859 ! sterol catabolic process GO:0016127 10 9 0,000 7,19E-03 0,01937158 GO:0006707|cholesterol catabolic process, ! oligosaccharyl transferase activity GO:0004576 9 9 0,000 7,19E-03 0,01935728 ! clathrin coat of coated pit GO:0030132 11 9 0,000 7,19E-03 0,01934301 ! SNARE complex GO:0031201 11 9 0,000 7,19E-03 0,01932875 ! negative regulation of osteoclast differentiation GO:0045671 10 9 0,000 7,19E-03 0,01931452 ! negative regulation of glucose transport GO:0010829 10 9 0,000 7,19E-03 0,01930031 ! methionine biosynthetic process GO:0009086 11 9 0,000 7,19E-03 0,01928612 ! peptidoglycan binding GO:0042834 9 9 0,000 7,19E-03 0,01927195 ! serine family amino acid biosynthetic process GO:0009070 10 9 0,000 7,19E-03 0,0192578 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 7,19E-03 0,01924367 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! nicotinamide nucleotide biosynthetic process GO:0019359 10 9 0,000 7,19E-03 0,01922956 ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 9 9 0,000 7,19E-03 0,01921547 GO:0003756|protein disulfide isomerase activity, ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 7,19E-03 0,0192014 ! beta-1,3-galactosyltransferase activity GO:0048531 10 9 0,000 7,19E-03 0,01918736 ! detection of bacterium GO:0016045 10 9 0,000 7,19E-03 0,01917333 ! lymphocyte activation during immune response GO:0002285 9 9 0,000 7,19E-03 0,01915933 ! embryonic gut development GO:0048566 10 9 0,000 7,19E-03 0,01914534 ! hydrolase activity, acting on ether bonds GO:0016801 10 9 0,000 7,19E-03 0,01913138 ! desmosome GO:0030057 10 9 0,000 7,19E-03 0,01911743 ! long-chain-fatty-acid-CoA ligase activity GO:0004467 9 9 0,000 7,19E-03 0,01910351 ! T cell receptor signaling pathway GO:0050852 14 9 0,000 7,19E-03 0,01908961 ! positive regulation of calcium-mediated signaling GO:0050850 11 9 0,000 7,19E-03 0,01907572 ! actin filament polymerization GO:0030041 10 9 0,000 7,19E-03 0,01906186 ! negative regulation of B cell activation GO:0050869 10 9 0,000 7,19E-03 0,01904802 ! establishment of cell polarity GO:0030010 10 9 0,000 7,19E-03 0,01903419 ! regulation of synapse organization GO:0050807 10 9 0,000 7,19E-03 0,01902039 ! septin complex GO:0031105 10 9 0,000 7,19E-03 0,01900661 GO:0032156|septin cytoskeleton, ! cholesterol transporter activity GO:0017127 9 9 0,000 7,19E-03 0,01899284 ! anchoring collagen GO:0030934 9 9 0,000 7,19E-03 0,0189791 ! defense response to Gram-negative bacterium GO:0050829 10 9 0,000 7,19E-03 0,01896538 ! regulation of developmental growth GO:0048638 11 9 0,000 7,19E-03 0,01895167 ! negative regulation of smooth muscle cell proliferation GO:0048662 10 9 0,000 7,19E-03 0,01893799 ! GMP binding GO:0019002 11 9 0,000 7,19E-03 0,01892433 GO:0030553|cGMP binding, ! photoreceptor activity GO:0009881 10 9 0,000 7,19E-03 0,01891068 ! virus-host interaction GO:0019048 13 9 0,000 7,19E-03 0,01889706 ! pentose-phosphate shunt GO:0006098 11 9 0,000 7,19E-03 0,01888345 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 7,19E-03 0,01886987 ! negative regulation of lipid catabolic process GO:0050995 11 9 0,000 7,19E-03 0,0188563 ! non-recombinational repair GO:0000726 10 9 0,000 7,19E-03 0,01884276 GO:0006303|double-strand break repair via nonhomologous end joining, ! cell volume homeostasis GO:0006884 10 9 0,000 7,19E-03 0,01882923 ! nuclear telomere cap complex GO:0000783 10 9 0,000 7,19E-03 0,01881572 GO:0000782|telomere cap complex, ! activin binding GO:0048185 10 9 0,000 7,19E-03 0,01880223 ! social behavior GO:0035176 10 9 0,000 7,19E-03 0,01878877 ! regulation of positive chemotaxis GO:0050926 11 9 0,000 7,19E-03 0,01877532 GO:0050927|positive regulation of positive chemotaxis, ! perikaryon GO:0043204 11 9 0,000 7,19E-03 0,01876189 ! nitric oxide biosynthetic process GO:0006809 10 9 0,000 7,19E-03 0,01874848 ! mating GO:0007618 11 9 0,000 7,19E-03 0,01873508 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 9 0,000 7,19E-03 0,01872171 ! rhythmic behavior GO:0007622 11 9 0,000 7,19E-03 0,01870836 ! phospholipid efflux GO:0033700 10 9 0,000 7,19E-03 0,01869502 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 7,19E-03 0,01868171 ! poly-purine tract binding GO:0070717 9 9 0,000 7,19E-03 0,01866841 ! T cell proliferation GO:0042098 10 9 0,000 7,19E-03 0,01865513 ! retinol dehydrogenase activity GO:0004745 9 9 0,000 7,19E-03 0,01864187 ! negative regulation of cell-matrix adhesion GO:0001953 10 9 0,000 7,19E-03 0,01862863 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 9 9 0,000 7,19E-03 0,01861541 ! interleukin-1 binding GO:0019966 10 9 0,000 7,19E-03 0,01860221 ! glucosyltransferase activity GO:0046527 9 9 0,000 7,19E-03 0,01858903 ! platelet-derived growth factor receptor signaling pathway GO:0048008 14 9 0,000 7,19E-03 0,01857586 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 11 9 0,000 7,19E-03 0,01856272 ! ovulation GO:0030728 9 9 0,000 7,19E-03 0,01854959 ! acid phosphatase activity GO:0003993 18 9 0,000 7,19E-03 0,01853648 ! embryonic cranial skeleton morphogenesis GO:0048701 10 9 0,000 7,19E-03 0,01852339 ! ER overload response GO:0006983 11 9 0,000 7,19E-03 0,01851032 ! B cell proliferation GO:0042100 10 9 0,000 7,19E-03 0,01849726 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 11 9 0,000 7,19E-03 0,01848423 ! calcium-transporting ATPase activity GO:0005388 11 9 0,000 7,19E-03 0,01847121 ! mannose metabolic process GO:0006013 13 9 0,000 7,19E-03 0,01845821 ! lipid digestion GO:0044241 11 9 0,000 7,19E-03 0,01844523 ! tumor necrosis factor binding GO:0043120 9 9 0,000 7,19E-03 0,01843227 ! tRNA methyltransferase activity GO:0008175 9 9 0,000 7,19E-03 0,01841932 ! regulation of bone resorption GO:0045124 10 9 0,000 7,19E-03 0,0184064 ! brain morphogenesis GO:0048854 9 9 0,000 7,19E-03 0,01839349 ! positive regulation of alpha-beta T cell differentiation GO:0046638 10 9 0,000 7,19E-03 0,0183806 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 10 9 0,000 7,19E-03 0,01836773 ! synaptic vesicle membrane GO:0030672 9 9 0,000 7,19E-03 0,01835488 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 9 0,000 7,19E-03 0,01834204 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9 9 0,000 7,19E-03 0,01832922 ! kinesin binding GO:0019894 9 9 0,000 7,19E-03 0,01831642 ! multicellular organismal aging GO:0010259 18 9 0,000 7,19E-03 0,01830364 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 7,19E-03 0,01829088 ! protein import into peroxisome matrix GO:0016558 9 9 0,000 7,19E-03 0,01827813 ! mRNA polyadenylation GO:0006378 10 9 0,000 7,19E-03 0,0182654 ! neuropeptide Y receptor activity GO:0004983 10 9 0,000 7,19E-03 0,01825269 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 14 9 0,000 7,19E-03 0,01824 ! prostaglandin receptor activity GO:0004955 11 9 0,000 7,19E-03 0,01822732 ! caspase inhibitor activity GO:0043027 9 9 0,000 7,19E-03 0,01821466 ! adrenoceptor activity GO:0004935 12 9 0,000 7,19E-03 0,01820202 ! regulation of isotype switching GO:0045191 9 9 0,000 7,19E-03 0,0181894 ! positive regulation of leukocyte migration GO:0002687 10 9 0,000 7,19E-03 0,0181768 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 10 9 0,000 7,19E-03 0,01816421 ! positive regulation of ATPase activity GO:0032781 11 9 0,000 7,19E-03 0,01815164 ! nonprotein amino acid metabolic process GO:0019794 19 9 0,000 7,19E-03 0,01813909 ! ionotropic glutamate receptor complex GO:0008328 14 9 0,000 7,19E-03 0,01812655 ! Notch binding GO:0005112 10 9 0,000 7,19E-03 0,01811403 ! ATPase regulator activity GO:0060590 10 9 0,000 7,19E-03 0,01810153 ! gamma-tubulin complex GO:0000930 19 9 0,000 7,19E-03 0,01808905 ! pyrimidine base metabolic process GO:0006206 10 9 0,000 7,19E-03 0,01807658 ! establishment or maintenance of apical/basal cell polarity GO:0035088 10 9 0,000 7,19E-03 0,01806413 ! tubulin-tyrosine ligase activity GO:0004835 10 9 0,000 7,19E-03 0,0180517 ! alcohol dehydrogenase (NAD) activity GO:0004022 10 9 0,000 7,19E-03 0,01803928 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 12 10 0,000 7,986E-03 0,02002239 ! oligosaccharide biosynthetic process GO:0009312 10 10 0,000 7,986E-03 0,02000864 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 10 0,000 7,986E-03 0,0199949 ! sleep GO:0030431 11 10 0,000 7,986E-03 0,01998119 ! positive regulation of lipid biosynthetic process GO:0046889 10 10 0,000 7,986E-03 0,01996749 ! lipid particle GO:0005811 10 10 0,000 7,986E-03 0,01995382 ! filopodium assembly GO:0046847 14 10 0,000 7,986E-03 0,01994016 ! UTP metabolic process GO:0046051 12 10 0,000 7,986E-03 0,01992652 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 13 10 0,000 7,986E-03 0,0199129 ! guanylate kinase activity GO:0004385 14 10 0,000 7,986E-03 0,0198993 ! integral to mitochondrial membrane GO:0032592 10 10 0,000 7,986E-03 0,01988572 ! COPI coating of Golgi vesicle GO:0048205 11 10 0,000 7,986E-03 0,01987215 GO:0048200|Golgi transport vesicle coating, ! platelet alpha granule membrane GO:0031092 11 10 0,000 7,986E-03 0,0198586 ! macromolecule transmembrane transporter activity GO:0022884 11 10 0,000 7,986E-03 0,01984508 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 10 0,000 7,986E-03 0,01983157 ! thyroid hormone receptor coactivator activity GO:0030375 11 10 0,000 7,986E-03 0,01981808 GO:0010861|thyroid hormone receptor activator activity, ! regulation of receptor activity GO:0010469 12 10 0,000 7,986E-03 0,0198046 ! lung alveolus development GO:0048286 11 10 0,000 7,986E-03 0,01979115 ! regulation of chemokine biosynthetic process GO:0045073 11 10 0,000 7,986E-03 0,01977771 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 7,986E-03 0,0197643 ! negative regulation of striated muscle development GO:0045843 11 10 0,000 7,986E-03 0,0197509 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 7,986E-03 0,01973752 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 11 10 0,000 7,986E-03 0,01972415 ! regulation of mRNA processing GO:0050684 12 10 0,000 7,986E-03 0,01971081 ! positive regulation of survival gene product expression GO:0045885 12 10 0,000 7,986E-03 0,01969748 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 11 10 0,000 7,986E-03 0,01968417 ! transforming growth factor beta binding GO:0050431 11 10 0,000 7,986E-03 0,01967088 ! histidine metabolic process GO:0006547 10 10 0,000 7,986E-03 0,01965761 GO:0009075|histidine family amino acid metabolic process, ! glucan biosynthetic process GO:0009250 10 10 0,000 7,986E-03 0,01964435 GO:0005978|glycogen biosynthetic process, ! endosome organization GO:0007032 13 10 0,000 7,986E-03 0,01963111 ! death receptor activity GO:0005035 11 10 0,000 7,986E-03 0,01961789 ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 7,986E-03 0,01960469 ! entry into host cell GO:0030260 11 10 0,000 7,986E-03 0,01959151 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 10 10 0,000 7,986E-03 0,01957834 ! filamentous actin GO:0031941 11 10 0,000 7,986E-03 0,01956519 ! behavioral fear response GO:0001662 12 10 0,000 7,986E-03 0,01955206 GO:0002209|behavioral defense response, ! bone mineralization GO:0030282 12 10 0,000 7,986E-03 0,01953895 ! negative regulation of ossification GO:0030279 12 10 0,000 7,986E-03 0,01952585 ! phosphatidylcholine biosynthetic process GO:0006656 11 10 0,000 7,986E-03 0,01951278 ! macrophage differentiation GO:0030225 11 10 0,000 7,986E-03 0,01949971 ! positive regulation of phagocytosis GO:0050766 11 10 0,000 7,986E-03 0,01948667 ! recycling endosome membrane GO:0055038 11 10 0,000 7,986E-03 0,01947365 ! regulation of fat cell differentiation GO:0045598 11 10 0,000 7,986E-03 0,01946064 ! snRNA metabolic process GO:0016073 10 10 0,000 7,986E-03 0,01944765 GO:0016180|snRNA processing, ! glycosphingolipid biosynthetic process GO:0006688 11 10 0,000 7,986E-03 0,01943467 ! regulation of mitochondrial membrane potential GO:0051881 11 10 0,000 7,986E-03 0,01942172 ! purine ribonucleotide catabolic process GO:0009154 10 10 0,000 7,986E-03 0,01940878 ! immunoglobulin production during immune response GO:0002381 10 10 0,000 7,986E-03 0,01939585 ! nitric oxide metabolic process GO:0046209 20 10 0,000 7,986E-03 0,01938295 ! induction of an organ GO:0001759 12 10 0,000 7,986E-03 0,01937006 ! response to estradiol stimulus GO:0032355 11 10 0,000 7,986E-03 0,01935719 ! synaptic vesicle endocytosis GO:0048488 12 10 0,000 7,986E-03 0,01934434 ! negative regulation of MAPKKK cascade GO:0043409 12 10 0,000 7,986E-03 0,0193315 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 10 0,000 7,986E-03 0,01931868 ! MHC class II receptor activity GO:0032395 14 10 0,000 7,986E-03 0,01930588 ! peptidyl-lysine modification GO:0018205 11 10 0,000 7,986E-03 0,01929309 ! ribonuclease P activity GO:0004526 10 10 0,000 7,986E-03 0,01928033 ! COPI vesicle coat GO:0030126 12 10 0,000 7,986E-03 0,01926757 GO:0030663|COPI coated vesicle membrane, ! telomere maintenance via telomere lengthening GO:0010833 21 10 0,000 7,986E-03 0,01925484 ! vitamin transporter activity GO:0051183 12 10 0,000 7,986E-03 0,01924212 ! snRNA binding GO:0017069 11 10 0,000 7,986E-03 0,01922942 ! negative regulation of osteoblast differentiation GO:0045668 12 10 0,000 7,986E-03 0,01921674 ! heparan sulfate sulfotransferase activity GO:0034483 10 10 0,000 7,986E-03 0,01920407 ! fatty-acid ligase activity GO:0015645 10 10 0,000 7,986E-03 0,01919142 ! intramolecular transferase activity, phosphotransferases GO:0016868 11 10 0,000 7,986E-03 0,01917878 ! quaternary ammonium group transport GO:0015697 10 10 0,000 7,986E-03 0,01916617 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 10 10 0,000 7,986E-03 0,01915357 ! metalloenzyme inhibitor activity GO:0048551 11 10 0,000 7,986E-03 0,01914098 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! anterior/posterior axis specification GO:0009948 14 10 0,000 7,986E-03 0,01912841 ! regulation of RNA splicing GO:0043484 13 10 0,000 7,986E-03 0,01911586 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 10 10 0,000 7,986E-03 0,01910333 ! trophectodermal cell differentiation GO:0001829 11 10 0,000 7,986E-03 0,01909081 ! positive regulation of neuron apoptosis GO:0043525 11 10 0,000 7,986E-03 0,01907831 ! extracellular matrix binding GO:0050840 11 10 0,000 7,986E-03 0,01906582 ! regulation of synapse structure and activity GO:0050803 11 10 0,000 7,986E-03 0,01905335 ! autophagic vacuole formation GO:0000045 11 10 0,000 7,986E-03 0,0190409 ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 7,986E-03 0,01902846 ! negative regulation of cell projection organization GO:0031345 14 10 0,000 7,986E-03 0,01901604 ! negative regulation of cellular catabolic process GO:0031330 11 10 0,000 7,986E-03 0,01900364 ! rough endoplasmic reticulum membrane GO:0030867 10 10 0,000 7,986E-03 0,01899125 ! thyroid gland development GO:0030878 12 10 0,000 7,986E-03 0,01897888 ! DNA bending activity GO:0008301 11 10 0,000 7,986E-03 0,01896652 ! neutral lipid biosynthetic process GO:0046460 10 10 0,000 7,986E-03 0,01895418 GO:0046463|acylglycerol biosynthetic process, ! embryonic hindlimb morphogenesis GO:0035116 11 10 0,000 7,986E-03 0,01894186 ! embryonic forelimb morphogenesis GO:0035115 12 10 0,000 7,986E-03 0,01892955 ! regulation of glucan biosynthetic process GO:0010962 10 10 0,000 7,986E-03 0,01891726 GO:0005979|regulation of glycogen biosynthetic process, GO:0032885|regulation of polysaccharide biosynthetic process, ! secondary active sulfate transmembrane transporter activity GO:0008271 11 10 0,000 7,986E-03 0,01890498 ! regulation of glycolysis GO:0006110 11 10 0,000 7,986E-03 0,01889272 ! nucleotidase activity GO:0008252 10 10 0,000 7,986E-03 0,01888048 ! phosphatidylinositol phosphate kinase activity GO:0016307 11 10 0,000 7,986E-03 0,01886825 ! dipeptidyl-peptidase activity GO:0008239 12 10 0,000 7,986E-03 0,01885603 ! androgen metabolic process GO:0008209 11 10 0,000 7,986E-03 0,01884384 ! lateral plasma membrane GO:0016328 13 10 0,000 7,986E-03 0,01883166 ! MAP kinase kinase activity GO:0004708 12 10 0,000 7,986E-03 0,01881949 ! cation:amino acid symporter activity GO:0005416 12 10 0,000 7,986E-03 0,01880734 ! startle response GO:0001964 13 10 0,000 7,986E-03 0,01879521 ! amyloid precursor protein metabolic process GO:0042982 12 10 0,000 7,986E-03 0,01878309 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 12 10 0,000 7,986E-03 0,01877099 ! positive regulation of endothelial cell proliferation GO:0001938 13 10 0,000 7,986E-03 0,0187589 ! 3'-5'-exoribonuclease activity GO:0000175 10 10 0,000 7,986E-03 0,01874683 ! spinal cord patterning GO:0021511 12 10 0,000 7,986E-03 0,01873477 ! peptide or protein amino-terminal blocking GO:0018409 11 10 0,000 7,986E-03 0,01872273 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 10 10 0,000 7,986E-03 0,01871071 GO:0033549|MAP kinase phosphatase activity, ! response to X-ray GO:0010165 11 10 0,000 7,986E-03 0,0186987 ! embryonic eye morphogenesis GO:0048048 14 10 0,000 7,986E-03 0,01868671 ! sodium:potassium-exchanging ATPase activity GO:0005391 12 10 0,000 7,986E-03 0,01867473 ! zinc ion transmembrane transporter activity GO:0005385 13 10 0,000 7,986E-03 0,01866276 ! positive regulation of glycogen metabolic process GO:0070875 11 10 0,000 7,986E-03 0,01865082 ! glucose transmembrane transporter activity GO:0005355 10 10 0,000 7,986E-03 0,01863888 ! regulation of intracellular pH GO:0051453 10 10 0,000 7,986E-03 0,01862696 ! retrograde transport, endosome to Golgi GO:0042147 12 10 0,000 7,986E-03 0,01861506 ! regulation of multicellular organismal metabolic process GO:0044246 11 10 0,000 7,986E-03 0,01860318 ! adult heart development GO:0007512 14 10 0,000 7,986E-03 0,0185913 ! neuromuscular junction development GO:0007528 12 10 0,000 7,986E-03 0,01857945 ! carbohydrate phosphatase activity GO:0019203 11 10 0,000 7,986E-03 0,01856761 ! O-methyltransferase activity GO:0008171 10 10 0,000 7,986E-03 0,01855578 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 10 10 0,000 7,986E-03 0,01854397 ! signalosome GO:0008180 10 10 0,000 7,986E-03 0,01853217 ! lysophospholipase activity GO:0004622 19 10 0,000 7,986E-03 0,01852039 ! prefoldin complex GO:0016272 10 10 0,000 7,986E-03 0,01850862 ! alpha-beta T cell differentiation GO:0046632 12 10 0,000 7,986E-03 0,01849687 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 10 0,000 7,986E-03 0,01848514 ! positive regulation of T cell mediated immunity GO:0002711 10 10 0,000 7,986E-03 0,01847341 ! nucleoside bisphosphate metabolic process GO:0033865 10 10 0,000 7,986E-03 0,01846171 ! endocytic vesicle membrane GO:0030666 10 10 0,000 7,986E-03 0,01845001 ! gland morphogenesis GO:0022612 11 10 0,000 7,986E-03 0,01843834 ! icosanoid receptor activity GO:0004953 13 10 0,000 7,986E-03 0,01842668 GO:0004954|prostanoid receptor activity, ! regulation of macrophage activation GO:0043030 11 10 0,000 7,986E-03 0,01841503 ! peptide transporter activity GO:0015197 10 10 0,000 7,986E-03 0,01840339 ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 10 10 0,000 7,986E-03 0,01839178 ! regulation of leukocyte migration GO:0002685 11 10 0,000 7,986E-03 0,01838017 ! muscle maintenance GO:0046716 10 10 0,000 7,986E-03 0,01836858 ! acid secretion GO:0046717 12 10 0,000 7,986E-03 0,01835701 ! retinoid-X receptor activity GO:0004886 11 10 0,000 7,986E-03 0,01834545 ! catecholamine biosynthetic process GO:0042423 11 10 0,000 7,986E-03 0,0183339 ! thyroid hormone metabolic process GO:0042403 11 10 0,000 7,986E-03 0,01832237 ! GTPase inhibitor activity GO:0005095 21 10 0,000 7,986E-03 0,01831086 ! somatic recombination of immunoglobulin gene segments GO:0016447 10 10 0,000 7,986E-03 0,01829936 ! pattern recognition receptor activity GO:0008329 10 10 0,000 7,986E-03 0,01828787 ! quinone cofactor metabolic process GO:0042375 11 10 0,000 7,986E-03 0,01827639 ! regulation of organic acid transport GO:0032890 12 10 0,000 7,986E-03 0,01826494 ! platelet-derived growth factor receptor binding GO:0005161 14 10 0,000 7,986E-03 0,01825349 ! C-acyltransferase activity GO:0016408 12 10 0,000 7,986E-03 0,01824206 ! cAMP-dependent protein kinase complex GO:0005952 12 10 0,000 7,986E-03 0,01823065 ! water channel activity GO:0015250 15 10 0,000 7,986E-03 0,01821925 ! phospholipase inhibitor activity GO:0004859 10 10 0,000 7,986E-03 0,01820786 ! regulation of embryonic development GO:0045995 12 10 0,000 7,986E-03 0,01819649 ! acrosome reaction GO:0007340 12 10 0,000 7,986E-03 0,01818513 ! mitochondrion localization GO:0051646 10 10 0,000 7,986E-03 0,01817378 ! cilium part GO:0044441 10 10 0,000 7,986E-03 0,01816245 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 12 11 0,000 8,781E-03 0,01995879 ! 'de novo' posttranslational protein folding GO:0051084 11 11 0,000 8,781E-03 0,01994636 ! negative regulation of blood pressure GO:0045776 13 11 0,000 8,781E-03 0,01993395 ! centriole GO:0005814 11 11 0,000 8,781E-03 0,01992155 ! cadmium ion binding GO:0046870 15 11 0,000 8,781E-03 0,01990917 ! hemoglobin complex GO:0005833 13 11 0,000 8,781E-03 0,01989681 ! CTP metabolic process GO:0046036 13 11 0,000 8,781E-03 0,01988445 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0009148|pyrimidine nucleoside triphosphate biosynthetic process, ! regulation of neurotransmitter secretion GO:0046928 12 11 0,000 8,781E-03 0,01987212 ! response to pain GO:0048265 12 11 0,000 8,781E-03 0,0198598 ! regulation of viral genome replication GO:0045069 13 11 0,000 8,781E-03 0,01984749 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 11 11 0,000 8,781E-03 0,01983521 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 12 11 0,000 8,781E-03 0,01982293 ! nucleotide-sugar metabolic process GO:0009225 13 11 0,000 8,781E-03 0,01981067 ! regulation of catecholamine secretion GO:0050433 12 11 0,000 8,781E-03 0,01979843 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 8,781E-03 0,0197862 ! peptide antigen binding GO:0042605 14 11 0,000 8,781E-03 0,01977399 ! polyamine metabolic process GO:0006595 11 11 0,000 8,781E-03 0,01976179 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 13 11 0,000 8,781E-03 0,0197496 GO:0045125|bioactive lipid receptor activity, ! nucleobase biosynthetic process GO:0046112 13 11 0,000 8,781E-03 0,01973743 ! regulation of calcium ion transport into cytosol GO:0010522 15 11 0,000 8,781E-03 0,01972528 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 12 11 0,000 8,781E-03 0,01971314 GO:0002717|positive regulation of natural killer cell mediated immunity, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 12 11 0,000 8,781E-03 0,01970102 ! protein homotetramerization GO:0051289 13 11 0,000 8,781E-03 0,01968891 ! regulation of gliogenesis GO:0014013 13 11 0,000 8,781E-03 0,01967682 GO:0045685|regulation of glial cell differentiation, ! oligodendrocyte development GO:0014003 11 11 0,000 8,781E-03 0,01966474 ! cytoskeletal adaptor activity GO:0008093 17 11 0,000 8,781E-03 0,01965267 ! regulation of circadian rhythm GO:0042752 11 11 0,000 8,781E-03 0,01964062 ! low-density lipoprotein receptor binding GO:0050750 11 11 0,000 8,781E-03 0,01962859 ! response to dsRNA GO:0043331 21 11 0,000 8,781E-03 0,01961657 ! response to amine stimulus GO:0014075 15 11 0,000 8,781E-03 0,01960456 GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 14 11 0,000 8,781E-03 0,01959257 ! sphingomyelin metabolic process GO:0006684 13 11 0,000 8,781E-03 0,0195806 ! cell wall macromolecule catabolic process GO:0016998 14 11 0,000 8,781E-03 0,01956864 ! spinal cord motor neuron differentiation GO:0021522 12 11 0,000 8,781E-03 0,01955669 ! retinal binding GO:0016918 11 11 0,000 8,781E-03 0,01954476 ! leukocyte activation during immune response GO:0002366 11 11 0,000 8,781E-03 0,01953284 GO:0002263|cell activation during immune response, ! regulation of sterol transport GO:0032371 12 11 0,000 8,781E-03 0,01952094 GO:0032374|regulation of cholesterol transport, ! beta-tubulin binding GO:0048487 14 11 0,000 8,781E-03 0,01950905 ! autonomic nervous system development GO:0048483 12 11 0,000 8,781E-03 0,01949717 ! negative regulation of lipid transport GO:0032369 12 11 0,000 8,781E-03 0,01948531 ! photoreceptor outer segment GO:0001750 12 11 0,000 8,781E-03 0,01947347 ! positive regulation of interleukin-1 secretion GO:0050716 12 11 0,000 8,781E-03 0,01946164 ! peptidyl-threonine modification GO:0018210 15 11 0,000 8,781E-03 0,01944982 ! clathrin coat of trans-Golgi network vesicle GO:0030130 15 11 0,000 8,781E-03 0,01943802 ! regulation of interleukin-1 beta secretion GO:0050706 12 11 0,000 8,781E-03 0,01942623 ! regulation of epidermis development GO:0045682 14 11 0,000 8,781E-03 0,01941446 ! positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 11 11 0,000 8,781E-03 0,0194027 ! midbrain development GO:0030901 12 11 0,000 8,781E-03 0,01939095 ! musculoskeletal movement GO:0050881 12 11 0,000 8,781E-03 0,01937922 GO:0050879|multicellular organismal movement, ! histone deacetylase binding GO:0042826 11 11 0,000 8,781E-03 0,01936751 ! regulation of RNA stability GO:0043487 13 11 0,000 8,781E-03 0,0193558 GO:0043488|regulation of mRNA stability, ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 11 11 0,000 8,781E-03 0,01934412 ! cell killing GO:0001906 13 11 0,000 8,781E-03 0,01933244 ! regulation of cellular carbohydrate catabolic process GO:0043471 13 11 0,000 8,781E-03 0,01932078 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 12 11 0,000 8,781E-03 0,01930914 ! carbon-sulfur lyase activity GO:0016846 11 11 0,000 8,781E-03 0,0192975 ! cerebellar cortex morphogenesis GO:0021696 13 11 0,000 8,781E-03 0,01928589 ! regulation of blood vessel endothelial cell migration GO:0043535 13 11 0,000 8,781E-03 0,01927428 ! folic acid binding GO:0005542 12 11 0,000 8,781E-03 0,01926269 ! mRNA 3'-end processing GO:0031124 12 11 0,000 8,781E-03 0,01925112 ! regulation of calcium-mediated signaling GO:0050848 13 11 0,000 8,781E-03 0,01923955 ! positive regulation of protein polymerization GO:0032273 11 11 0,000 8,781E-03 0,01922801 ! microspike assembly GO:0030035 15 11 0,000 8,781E-03 0,01921647 ! lamellipodium assembly GO:0030032 22 11 0,000 8,781E-03 0,01920495 ! fibrillar collagen GO:0005583 12 11 0,000 8,781E-03 0,01919344 ! inner ear receptor cell differentiation GO:0060113 12 11 0,000 8,781E-03 0,01918195 ! cytoplasmic sequestering of protein GO:0051220 12 11 0,000 8,781E-03 0,01917047 ! negative regulation of muscle development GO:0048635 13 11 0,000 8,781E-03 0,01915901 ! very-long-chain fatty acid metabolic process GO:0000038 12 11 0,000 8,781E-03 0,01914755 ! synaptonemal complex GO:0000795 11 11 0,000 8,781E-03 0,01913612 ! reproductive cellular process GO:0048610 13 11 0,000 8,781E-03 0,01912469 ! cortical actin cytoskeleton organization GO:0030866 12 11 0,000 8,781E-03 0,01911328 ! Golgi vesicle budding GO:0048194 12 11 0,000 8,781E-03 0,01910188 ! response to cAMP GO:0051591 11 11 0,000 8,781E-03 0,0190905 ! detection of mechanical stimulus GO:0050982 13 11 0,000 8,781E-03 0,01907913 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 13 11 0,000 8,781E-03 0,01906777 ! regulation of cell projection assembly GO:0060491 11 11 0,000 8,781E-03 0,01905643 ! negative regulation of transcription factor import into nucleus GO:0042992 11 11 0,000 8,781E-03 0,0190451 ! positive regulation of transcription factor import into nucleus GO:0042993 13 11 0,000 8,781E-03 0,01903378 ! macromolecular complex remodeling GO:0034367 11 11 0,000 8,781E-03 0,01902248 GO:0034368|protein-lipid complex remodeling, GO:0034369|plasma lipoprotein particle remodeling, ! protein serine/threonine/tyrosine kinase activity GO:0004712 13 11 0,000 8,781E-03 0,01901119 ! glycerol ether biosynthetic process GO:0046504 11 11 0,000 8,781E-03 0,01899991 ! drug transport GO:0015893 12 11 0,000 8,781E-03 0,01898865 ! FMN binding GO:0010181 12 11 0,000 8,781E-03 0,0189774 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 11 0,000 8,781E-03 0,01896617 ! water transporter activity GO:0005372 17 11 0,000 8,781E-03 0,01895494 ! regulation of glycogen metabolic process GO:0070873 12 11 0,000 8,781E-03 0,01894374 GO:0032881|regulation of polysaccharide metabolic process, ! substrate-bound cell migration GO:0006929 13 11 0,000 8,781E-03 0,01893254 ! multicellular organism growth GO:0035264 12 11 0,000 8,781E-03 0,01892136 ! integrator complex GO:0032039 11 11 0,000 8,781E-03 0,01891019 ! L-glutamate transmembrane transporter activity GO:0005313 13 11 0,000 8,781E-03 0,01889903 GO:0015172|acidic amino acid transmembrane transporter activity, ! DNA integration GO:0015074 11 11 0,000 8,781E-03 0,01888789 ! brush border membrane GO:0031526 12 11 0,000 8,781E-03 0,01887676 ! actin cytoskeleton reorganization GO:0031532 14 11 0,000 8,781E-03 0,01886564 ! macroautophagy GO:0016236 12 11 0,000 8,781E-03 0,01885454 ! protein disulfide oxidoreductase activity GO:0015035 11 11 0,000 8,781E-03 0,01884345 ! neuromuscular junction GO:0031594 12 11 0,000 8,781E-03 0,01883237 ! positive regulation of peptide secretion GO:0002793 13 11 0,000 8,781E-03 0,0188213 ! positive regulation of alpha-beta T cell activation GO:0046635 12 11 0,000 8,781E-03 0,01881025 ! organic anion transmembrane transporter activity GO:0008514 11 11 0,000 8,781E-03 0,01879921 ! response to antibiotic GO:0046677 13 11 0,000 8,781E-03 0,01878819 ! protein-hormone receptor activity GO:0016500 12 11 0,000 8,781E-03 0,01877717 ! bile acid transmembrane transporter activity GO:0015125 13 11 0,000 8,781E-03 0,01876617 ! proteasome accessory complex GO:0022624 11 11 0,000 8,781E-03 0,01875519 ! neuroblast proliferation GO:0007405 13 11 0,000 8,781E-03 0,01874421 ! non-G-protein coupled 7TM receptor activity GO:0004926 14 11 0,000 8,781E-03 0,01873325 ! negative regulation of neurological system process GO:0031645 13 11 0,000 8,781E-03 0,0187223 ! nitric oxide mediated signal transduction GO:0007263 12 11 0,000 8,781E-03 0,01871136 ! protein kinase C binding GO:0005080 11 11 0,000 8,781E-03 0,01870044 ! transforming growth factor beta receptor, cytoplasmic mediator activity GO:0005072 12 11 0,000 8,781E-03 0,01868953 ! male genitalia development GO:0030539 15 11 0,000 8,781E-03 0,01867863 ! receptor inhibitor activity GO:0030547 12 11 0,000 8,781E-03 0,01866775 GO:0048019|receptor antagonist activity, ! estrogen receptor signaling pathway GO:0030520 12 11 0,000 8,781E-03 0,01865688 ! L-fucose metabolic process GO:0042354 13 11 0,000 8,781E-03 0,01864602 ! palmitoyltransferase activity GO:0016409 11 11 0,000 8,781E-03 0,01863517 ! arylsulfatase activity GO:0004065 12 11 0,000 8,781E-03 0,01862434 ! sterol transporter activity GO:0015248 11 11 0,000 8,781E-03 0,01861351 ! response to nicotine GO:0035094 13 11 0,000 8,781E-03 0,0186027 ! adenylate cyclase activity GO:0004016 11 11 0,000 8,781E-03 0,01859191 ! rRNA transcription GO:0009303 12 12 0,000 9,576E-03 0,02026274 ! ER-associated protein catabolic process GO:0030433 14 12 0,000 9,576E-03 0,020251 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of blood pressure GO:0045777 15 12 0,000 9,576E-03 0,02023926 ! superoxide anion generation GO:0042554 12 12 0,000 9,576E-03 0,02022754 ! pteridine and derivative biosynthetic process GO:0042559 22 12 0,000 9,576E-03 0,02021584 ! regulation of chemokine production GO:0032642 13 12 0,000 9,576E-03 0,02020415 ! male meiosis GO:0007140 12 12 0,000 9,576E-03 0,02019247 ! signal complex assembly GO:0007172 15 12 0,000 9,576E-03 0,0201808 ! GTP metabolic process GO:0046039 14 12 0,000 9,576E-03 0,02016915 ! retina morphogenesis in camera-type eye GO:0060042 16 12 0,000 9,576E-03 0,02015751 ! hair follicle morphogenesis GO:0031069 14 12 0,000 9,576E-03 0,02014589 ! voltage-gated sodium channel complex GO:0001518 15 12 0,000 9,576E-03 0,02013428 GO:0034706|sodium channel complex, ! RNA polyadenylation GO:0043631 13 12 0,000 9,576E-03 0,02012268 ! cartilage condensation GO:0001502 14 12 0,000 9,576E-03 0,02011109 ! polysome GO:0005844 14 12 0,000 9,576E-03 0,02009952 ! hippocampus development GO:0021766 13 12 0,000 9,576E-03 0,02008796 ! lipoprotein receptor binding GO:0070325 13 12 0,000 9,576E-03 0,02007642 ! beta-amyloid binding GO:0001540 12 12 0,000 9,576E-03 0,02006489 ! negative regulation of endocytosis GO:0045806 15 12 0,000 9,576E-03 0,02005337 ! regulation of interferon-gamma biosynthetic process GO:0045072 15 12 0,000 9,576E-03 0,02004186 ! regulation of exit from mitosis GO:0007096 31 12 0,000 9,576E-03 0,02003037 ! chylomicron GO:0042627 13 12 0,000 9,576E-03 0,02001889 ! T cell selection GO:0045058 22 12 0,000 9,576E-03 0,02000743 ! negative regulation of proteolysis GO:0045861 12 12 0,000 9,576E-03 0,01999598 ! glycolipid biosynthetic process GO:0009247 13 12 0,000 9,576E-03 0,01998454 ! WW domain binding GO:0050699 12 12 0,000 9,576E-03 0,01997311 ! methionine metabolic process GO:0006555 14 12 0,000 9,576E-03 0,0199617 ! nuclear heterochromatin GO:0005720 12 12 0,000 9,576E-03 0,0199503 ! glycine metabolic process GO:0006544 14 12 0,000 9,576E-03 0,01993891 ! plasma membrane organization GO:0007009 12 12 0,000 9,576E-03 0,01992753 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 9,576E-03 0,01991617 ! ribonucleotide catabolic process GO:0009261 12 12 0,000 9,576E-03 0,01990483 ! Golgi organization GO:0007030 15 12 0,000 9,576E-03 0,01989349 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 9,576E-03 0,01988217 ! integral to peroxisomal membrane GO:0005779 12 12 0,000 9,576E-03 0,01987086 ! integral to membrane of membrane fraction GO:0000299 13 12 0,000 9,576E-03 0,01985956 ! regulation of the force of heart contraction GO:0002026 13 12 0,000 9,576E-03 0,01984828 ! temperature homeostasis GO:0001659 13 12 0,000 9,576E-03 0,01983701 ! negative regulation of mitotic cell cycle GO:0045930 15 12 0,000 9,576E-03 0,01982575 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 9,576E-03 0,0198145 ! lipoprotein receptor activity GO:0030228 12 12 0,000 9,576E-03 0,01980327 ! cotranslational protein targeting to membrane GO:0006613 14 12 0,000 9,576E-03 0,01979205 ! axon cargo transport GO:0008088 13 12 0,000 9,576E-03 0,01978084 ! regulation of phagocytosis GO:0050764 14 12 0,000 9,576E-03 0,01976965 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 12 0,000 9,576E-03 0,01975847 ! nucleoside triphosphate catabolic process GO:0009143 12 12 0,000 9,576E-03 0,0197473 ! transcription elongation factor complex GO:0008023 12 12 0,000 9,576E-03 0,01973614 ! basal lamina GO:0005605 12 12 0,000 9,576E-03 0,019725 ! regulation of interleukin-1 secretion GO:0050704 13 12 0,000 9,576E-03 0,01971387 ! pancreatic ribonuclease activity GO:0004522 12 12 0,000 9,576E-03 0,01970275 ! tRNA-specific ribonuclease activity GO:0004549 12 12 0,000 9,576E-03 0,01969164 ! biomineral formation GO:0031214 14 12 0,000 9,576E-03 0,01968055 ! water homeostasis GO:0030104 12 12 0,000 9,576E-03 0,01966946 ! promoter binding GO:0010843 14 12 0,000 9,576E-03 0,0196584 ! regulation of erythrocyte differentiation GO:0045646 15 12 0,000 9,576E-03 0,01964734 ! intestinal absorption GO:0050892 14 12 0,000 9,576E-03 0,0196363 ! pseudouridine synthase activity GO:0009982 12 12 0,000 9,576E-03 0,01962526 ! oocyte differentiation GO:0009994 13 12 0,000 9,576E-03 0,01961424 ! oxygen transport GO:0015671 13 12 0,000 9,576E-03 0,01960324 GO:0005344|oxygen transporter activity, ! thymus development GO:0048538 13 12 0,000 9,576E-03 0,01959224 ! cholesterol efflux GO:0033344 13 12 0,000 9,576E-03 0,01958126 ! digestive tract morphogenesis GO:0048546 14 12 0,000 9,576E-03 0,01957029 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! racemase and epimerase activity GO:0016854 13 12 0,000 9,576E-03 0,01955933 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 14 12 0,000 9,576E-03 0,01954839 ! tropomyosin binding GO:0005523 12 12 0,000 9,576E-03 0,01953745 ! blastocyst formation GO:0001825 13 12 0,000 9,576E-03 0,01952653 ! regulation of telomere maintenance GO:0032204 16 12 0,000 9,576E-03 0,01951563 ! internal side of plasma membrane GO:0009898 16 12 0,000 9,576E-03 0,01950473 ! mannose binding GO:0005537 13 12 0,000 9,576E-03 0,01949384 ! phosphoprotein binding GO:0051219 14 12 0,000 9,576E-03 0,01948297 ! defense response to fungus GO:0050832 12 12 0,000 9,576E-03 0,01947211 ! embryonic placenta development GO:0001892 16 12 0,000 9,576E-03 0,01946126 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 9,576E-03 0,01945043 ! cell wall macromolecule metabolic process GO:0044036 15 12 0,000 9,576E-03 0,0194396 ! acyl-CoA binding GO:0000062 12 12 0,000 9,576E-03 0,01942879 ! cortical cytoskeleton organization GO:0030865 13 12 0,000 9,576E-03 0,01941799 ! regulation of nitric-oxide synthase activity GO:0050999 12 12 0,000 9,576E-03 0,0194072 ! copper ion transport GO:0006825 12 12 0,000 9,576E-03 0,01939643 ! calcium ion transport into cytosol GO:0060402 19 12 0,000 9,576E-03 0,01938567 ! inositol metabolic process GO:0006020 21 12 0,000 9,576E-03 0,01937491 ! vesicle targeting, to, from or within Golgi GO:0048199 13 12 0,000 9,576E-03 0,01936417 ! forelimb morphogenesis GO:0035136 15 12 0,000 9,576E-03 0,01935345 ! protein complex disassembly GO:0043241 15 12 0,000 9,576E-03 0,01934273 GO:0043624|cellular protein complex disassembly, ! ion channel inhibitor activity GO:0008200 15 12 0,000 9,576E-03 0,01933202 GO:0016248|channel inhibitor activity, ! low-density lipoprotein particle GO:0034362 13 12 0,000 9,576E-03 0,01932133 ! lipoprotein particle clearance GO:0034381 14 12 0,000 9,576E-03 0,01931065 ! receptor signaling protein tyrosine kinase activity GO:0004716 14 12 0,000 9,576E-03 0,01929998 ! endothelial cell differentiation GO:0045446 15 12 0,000 9,576E-03 0,01928933 ! exosome (RNase complex) GO:0000178 13 12 0,000 9,576E-03 0,01927868 ! DNA N-glycosylase activity GO:0019104 12 12 0,000 9,576E-03 0,01926805 ! endoderm development GO:0007492 13 12 0,000 9,576E-03 0,01925742 ! positive regulation of Ras protein signal transduction GO:0046579 25 12 0,000 9,576E-03 0,01924681 ! focal adhesion formation GO:0048041 16 12 0,000 9,576E-03 0,01923622 ! T cell receptor complex GO:0042101 31 12 0,000 9,576E-03 0,01922563 ! cellular carbohydrate catabolic process GO:0044275 25 12 0,000 9,576E-03 0,01921505 ! dicarboxylic acid transmembrane transporter activity GO:0005310 14 12 0,000 9,576E-03 0,01920449 ! CoA hydrolase activity GO:0016289 14 12 0,000 9,576E-03 0,01919394 ! histone acetyltransferase complex GO:0000123 14 12 0,000 9,576E-03 0,0191834 ! regulation of alpha-beta T cell differentiation GO:0046637 13 12 0,000 9,576E-03 0,01917287 ! alpha-beta T cell activation GO:0046631 14 12 0,000 9,576E-03 0,01916235 ! retinol binding GO:0019841 12 12 0,000 9,576E-03 0,01915185 ! regulation of organ growth GO:0046620 12 12 0,000 9,576E-03 0,01914135 ! regulation of natural killer cell mediated immunity GO:0002715 13 12 0,000 9,576E-03 0,01913087 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! vasoconstriction GO:0042310 13 12 0,000 9,576E-03 0,0191204 ! histone acetylation GO:0016573 13 12 0,000 9,576E-03 0,01910994 ! ribosome binding GO:0043022 13 12 0,000 9,576E-03 0,01909949 ! delayed rectifier potassium channel activity GO:0005251 14 12 0,000 9,576E-03 0,01908905 ! organic cation transmembrane transporter activity GO:0015101 12 12 0,000 9,576E-03 0,01907863 ! phosphate transmembrane transporter activity GO:0015114 14 12 0,000 9,576E-03 0,01906821 ! tissue regeneration GO:0042246 12 12 0,000 9,576E-03 0,01905781 ! sulfate transmembrane transporter activity GO:0015116 13 12 0,000 9,576E-03 0,01904742 ! adenylyltransferase activity GO:0070566 13 12 0,000 9,576E-03 0,01903704 ! germ cell nucleus GO:0043073 14 12 0,000 9,576E-03 0,01902667 ! trans-Golgi network transport vesicle membrane GO:0012510 16 12 0,000 9,576E-03 0,01901631 ! hexose transmembrane transporter activity GO:0015149 12 12 0,000 9,576E-03 0,01900597 ! hexosaminidase activity GO:0015929 12 12 0,000 9,576E-03 0,01899563 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 9,576E-03 0,01898531 ! activation of NF-kappaB-inducing kinase activity GO:0007250 14 12 0,000 9,576E-03 0,018975 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 13 12 0,000 9,576E-03 0,0189647 ! dopamine metabolic process GO:0042417 15 12 0,000 9,576E-03 0,01895441 ! somatic diversification of immunoglobulins GO:0016445 12 12 0,000 9,576E-03 0,01894413 ! phosphoinositide 3-kinase activity GO:0035004 14 12 0,000 9,576E-03 0,01893386 ! insulin-like growth factor receptor binding GO:0005159 14 12 0,000 9,576E-03 0,0189236 ! bacterial binding GO:0008367 14 12 0,000 9,576E-03 0,01891336 ! steroid hydroxylase activity GO:0008395 12 12 0,000 9,576E-03 0,01890312 ! cardiac cell differentiation GO:0035051 16 12 0,000 9,576E-03 0,0188929 ! phosphoinositide 3-kinase complex GO:0005942 14 12 0,000 9,576E-03 0,01888269 ! localization within membrane GO:0051668 13 12 0,000 9,576E-03 0,01887248 ! microtubule-based flagellum GO:0009434 12 12 0,000 9,576E-03 0,01886229 ! axoneme part GO:0044447 12 12 0,000 9,576E-03 0,01885211 ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01037004 0,02040448 ! neuron maturation GO:0042551 14 13 0,000 0,01037004 0,02039348 ! positive regulation of small GTPase mediated signal transduction GO:0051057 26 13 0,000 0,01037004 0,0203825 ! negative regulation of bone remodeling GO:0046851 15 13 0,000 0,01037004 0,02037152 ! bone remodeling GO:0046849 14 13 0,000 0,01037004 0,02036056 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01037004 0,0203496 ! regulation of receptor-mediated endocytosis GO:0048259 15 13 0,000 0,01037004 0,02033866 ! striated muscle thin filament GO:0005865 14 13 0,000 0,01037004 0,02032773 ! patterning of blood vessels GO:0001569 15 13 0,000 0,01037004 0,02031682 ! organelle fusion GO:0048284 16 13 0,000 0,01037004 0,02030591 ! palate development GO:0060021 15 13 0,000 0,01037004 0,02029502 ! induction of apoptosis via death domain receptors GO:0008625 16 13 0,000 0,01037004 0,02028413 ! arginine metabolic process GO:0006525 14 13 0,000 0,01037004 0,02027326 ! ER-Golgi intermediate compartment membrane GO:0033116 23 13 0,000 0,01037004 0,02026241 ! tyrosine metabolic process GO:0006570 15 13 0,000 0,01037004 0,02025156 ! response to retinoic acid GO:0032526 17 13 0,000 0,01037004 0,02024072 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 15 13 0,000 0,01037004 0,0202299 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lipase inhibitor activity GO:0055102 14 13 0,000 0,01037004 0,02021909 ! negative regulation of endothelial cell migration GO:0010596 15 13 0,000 0,01037004 0,02020829 ! fear response GO:0042596 15 13 0,000 0,01037004 0,0201975 ! epithelial cell development GO:0002064 22 13 0,000 0,01037004 0,02018672 ! branching involved in ureteric bud morphogenesis GO:0001658 14 13 0,000 0,01037004 0,02017595 GO:0060675|ureteric bud morphogenesis, ! positive regulation of fatty acid metabolic process GO:0045923 14 13 0,000 0,01037004 0,0201652 ! protein kinase activator activity GO:0030295 17 13 0,000 0,01037004 0,02015445 ! heparan sulfate proteoglycan metabolic process GO:0030201 13 13 0,000 0,01037004 0,02014372 ! positive regulation of foam cell differentiation GO:0010744 16 13 0,000 0,01037004 0,020133 ! protein targeting to peroxisome GO:0006625 13 13 0,000 0,01037004 0,02012229 ! NLS-bearing substrate import into nucleus GO:0006607 15 13 0,000 0,01037004 0,0201116 ! cranial nerve development GO:0021545 15 13 0,000 0,01037004 0,02010091 ! eye photoreceptor cell differentiation GO:0001754 17 13 0,000 0,01037004 0,02009023 GO:0042462|eye photoreceptor cell development, ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01037004 0,02007957 ! cerebellum morphogenesis GO:0021587 15 13 0,000 0,01037004 0,02006892 ! MHC class I receptor activity GO:0032393 20 13 0,000 0,01037004 0,02005828 ! exoribonuclease activity GO:0004532 13 13 0,000 0,01037004 0,02004765 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! intrinsic to peroxisomal membrane GO:0031231 13 13 0,000 0,01037004 0,02003703 ! COPI-coated vesicle GO:0030137 15 13 0,000 0,01037004 0,02002642 ! cofactor transporter activity GO:0051184 15 13 0,000 0,01037004 0,02001583 ! NADP metabolic process GO:0006739 15 13 0,000 0,01037004 0,02000524 ! negative regulation of macrophage differentiation GO:0045650 16 13 0,000 0,01037004 0,01999467 ! regulation of osteoclast differentiation GO:0045670 15 13 0,000 0,01037004 0,01998411 ! aromatic amino acid family catabolic process GO:0009074 13 13 0,000 0,01037004 0,01997355 ! eukaryotic cell surface binding GO:0043499 15 13 0,000 0,01037004 0,01996301 ! proximal/distal pattern formation GO:0009954 15 13 0,000 0,01037004 0,01995249 ! positive regulation of JNK cascade GO:0046330 17 13 0,000 0,01037004 0,01994197 ! positive regulation of glucose import GO:0046326 16 13 0,000 0,01037004 0,01993146 GO:0010828|positive regulation of glucose transport, ! epithelial to mesenchymal transition GO:0001837 13 13 0,000 0,01037004 0,01992096 ! ADP binding GO:0043531 15 13 0,000 0,01037004 0,01991048 ! defense response to Gram-positive bacterium GO:0050830 14 13 0,000 0,01037004 0,01990001 ! mismatched DNA binding GO:0030983 13 13 0,000 0,01037004 0,01988954 ! positive regulation of synaptic transmission GO:0050806 15 13 0,000 0,01037004 0,01987909 ! neuron fate specification GO:0048665 25 13 0,000 0,01037004 0,01986865 ! N-terminal protein amino acid modification GO:0031365 14 13 0,000 0,01037004 0,01985822 ! dicarboxylic acid transport GO:0006835 15 13 0,000 0,01037004 0,0198478 ! water transport GO:0006833 18 13 0,000 0,01037004 0,01983739 GO:0042044|fluid transport, ! replisome GO:0030894 24 13 0,000 0,01037004 0,019827 GO:0043601|nuclear replisome, ! cytosolic calcium ion transport GO:0060401 20 13 0,000 0,01037004 0,01981661 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01037004 0,01980624 ! inorganic anion exchanger activity GO:0005452 13 13 0,000 0,01037004 0,01979587 ! negative regulation of ion transport GO:0043271 15 13 0,000 0,01037004 0,01978552 ! retinoic acid receptor binding GO:0042974 14 13 0,000 0,01037004 0,01977518 ! blood vessel remodeling GO:0001974 16 13 0,000 0,01037004 0,01976484 ! myoblast differentiation GO:0045445 15 13 0,000 0,01037004 0,01975452 ! ventral spinal cord development GO:0021517 16 13 0,000 0,01037004 0,01974421 ! prenyltransferase activity GO:0004659 15 13 0,000 0,01037004 0,01973391 ! activation of MAPKK activity GO:0000186 13 13 0,000 0,01037004 0,01972362 ! protein histidine kinase activity GO:0004673 15 13 0,000 0,01037004 0,01971335 GO:0000155|two-component sensor activity, ! cullin-RING ubiquitin ligase complex GO:0031461 13 13 0,000 0,01037004 0,01970308 ! regulation of skeletal muscle fiber development GO:0048742 16 13 0,000 0,01037004 0,01969282 ! acyl-CoA dehydrogenase activity GO:0003995 14 13 0,000 0,01037004 0,01968258 ! exocrine system development GO:0035272 14 13 0,000 0,01037004 0,01967234 ! membrane protein proteolysis GO:0033619 14 13 0,000 0,01037004 0,01966212 GO:0006509|membrane protein ectodomain proteolysis, ! organic alcohol transport GO:0015850 17 13 0,000 0,01037004 0,0196519 ! calcium ion transmembrane transporter activity GO:0015085 15 13 0,000 0,01037004 0,0196417 ! L-glutamate transport GO:0015813 14 13 0,000 0,01037004 0,01963151 GO:0015800|acidic amino acid transport, ! embryo implantation GO:0007566 17 13 0,000 0,01037004 0,01962132 ! G1/S transition checkpoint GO:0031575 14 13 0,000 0,01037004 0,01961115 ! immunoglobulin binding GO:0019865 14 13 0,000 0,01037004 0,01960099 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,01037004 0,01959084 ! regulation of T cell mediated immunity GO:0002709 17 13 0,000 0,01037004 0,0195807 ! DNA unwinding during replication GO:0006268 14 13 0,000 0,01037004 0,01957057 ! genitalia development GO:0048806 18 13 0,000 0,01037004 0,01956045 ! regulation of interleukin-8 production GO:0032677 15 13 0,000 0,01037004 0,01955034 ! regulation of interleukin-12 production GO:0032655 13 13 0,000 0,01037004 0,01954024 ! MHC class I protein binding GO:0042288 23 13 0,000 0,01037004 0,01953016 ! histone deacetylation GO:0016575 14 13 0,000 0,01037004 0,01952008 ! calcium channel regulator activity GO:0005246 16 13 0,000 0,01037004 0,01951001 ! DNA methylation GO:0006306 15 13 0,000 0,01037004 0,01949995 GO:0006305|DNA alkylation, ! mRNA splice site selection GO:0006376 17 13 0,000 0,01037004 0,01948991 ! chromatin silencing GO:0006342 13 13 0,000 0,01037004 0,01947987 ! serotonin receptor activity GO:0004993 16 13 0,000 0,01037004 0,01946985 ! monosaccharide transmembrane transporter activity GO:0015145 13 13 0,000 0,01037004 0,01945983 ! T cell homeostasis GO:0043029 14 13 0,000 0,01037004 0,01944983 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01037004 0,01943983 ! diacylglycerol kinase activity GO:0004143 15 13 0,000 0,01037004 0,01942985 ! response to gamma radiation GO:0010332 14 13 0,000 0,01037004 0,01941987 ! synaptic transmission, cholinergic GO:0007271 14 13 0,000 0,01037004 0,01940991 ! retinoic acid receptor activity GO:0003708 15 13 0,000 0,01037004 0,01939995 ! purine base metabolic process GO:0006144 15 13 0,000 0,01037004 0,01939001 ! cAMP binding GO:0030552 15 13 0,000 0,01037004 0,01938008 ! biogenic amine catabolic process GO:0042402 14 13 0,000 0,01037004 0,01937015 ! negative regulation of BMP signaling pathway GO:0030514 14 13 0,000 0,01037004 0,01936024 ! regulation of axon extension GO:0030516 16 13 0,000 0,01037004 0,01935034 ! drug transporter activity GO:0015238 14 13 0,000 0,01037004 0,01934045 ! regulation of NF-kappaB import into nucleus GO:0042345 14 13 0,000 0,01037004 0,01933056 ! calcium-activated potassium channel activity GO:0015269 15 13 0,000 0,01037004 0,01932069 ! response to cold GO:0009409 13 13 0,000 0,01037004 0,01931083 ! cadherin binding GO:0045296 16 13 0,000 0,01037004 0,01930098 ! nucleolar part GO:0044452 13 13 0,000 0,01037004 0,01929113 ! tRNA modification GO:0006400 14 14 0,000 0,01116357 0,02075672 ! cis-Golgi network GO:0005801 16 14 0,000 0,01116357 0,02074615 ! negative regulation of hormone secretion GO:0046888 14 14 0,000 0,01116357 0,02073558 ! 'de novo' protein folding GO:0006458 14 14 0,000 0,01116357 0,02072503 ! organellar large ribosomal subunit GO:0000315 15 14 0,000 0,01116357 0,02071449 GO:0005762|mitochondrial large ribosomal subunit, ! phosphoinositide phosphorylation GO:0046854 18 14 0,000 0,01116357 0,02070396 ! peroxisomal transport GO:0043574 14 14 0,000 0,01116357 0,02069344 ! cardiac muscle contraction GO:0060048 15 14 0,000 0,01116357 0,02068293 ! dopamine receptor signaling pathway GO:0007212 19 14 0,000 0,01116357 0,02067243 ! mechanoreceptor differentiation GO:0042490 16 14 0,000 0,01116357 0,02066194 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 18 14 0,000 0,01116357 0,02065146 ! pseudouridine synthesis GO:0001522 14 14 0,000 0,01116357 0,020641 ! caspase activator activity GO:0008656 16 14 0,000 0,01116357 0,02063054 ! MHC class II protein complex GO:0042613 19 14 0,000 0,01116357 0,02062009 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01116357 0,02060966 ! cAMP-dependent protein kinase regulator activity GO:0008603 17 14 0,000 0,01116357 0,02059923 ! cation:cation antiporter activity GO:0015491 14 14 0,000 0,01116357 0,02058882 ! glycoprotein catabolic process GO:0006516 16 14 0,000 0,01116357 0,02057842 ! protein polyubiquitination GO:0000209 15 14 0,000 0,01116357 0,02056802 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 34 14 0,000 0,01116357 0,02055764 ! negative regulation of microtubule depolymerization GO:0007026 16 14 0,000 0,01116357 0,02054727 GO:0031114|regulation of microtubule depolymerization, ! cell-cell junction assembly GO:0007043 15 14 0,000 0,01116357 0,02053691 ! response to vitamin A GO:0033189 18 14 0,000 0,01116357 0,02052656 ! actin filament bundle formation GO:0051017 16 14 0,000 0,01116357 0,02051621 ! regulation of lipoprotein lipase activity GO:0051004 15 14 0,000 0,01116357 0,02050588 ! plasma membrane fusion GO:0045026 15 14 0,000 0,01116357 0,02049556 ! purine nucleoside monophosphate metabolic process GO:0009126 15 14 0,000 0,01116357 0,02048525 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 16 14 0,000 0,01116357 0,02047496 ! presynaptic membrane GO:0042734 14 14 0,000 0,01116357 0,02046467 ! negative regulation of immune response GO:0050777 21 14 0,000 0,01116357 0,02045439 ! gastrulation with mouth forming second GO:0001702 15 14 0,000 0,01116357 0,02044412 ! neural crest cell migration GO:0001755 15 14 0,000 0,01116357 0,02043386 ! anaphase-promoting complex GO:0005680 17 14 0,000 0,01116357 0,02042361 ! positive regulation of oxidoreductase activity GO:0051353 14 14 0,000 0,01116357 0,02041338 ! negative regulation of protein secretion GO:0050709 17 14 0,000 0,01116357 0,02040315 ! cofactor transport GO:0051181 16 14 0,000 0,01116357 0,02039293 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,01116357 0,02038273 ! protein-chromophore linkage GO:0018298 16 14 0,000 0,01116357 0,02037253 ! cobalt ion binding GO:0050897 14 14 0,000 0,01116357 0,02036234 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01116357 0,02035217 ! positive regulation of transmission of nerve impulse GO:0051971 16 14 0,000 0,01116357 0,020342 ! aspartate family amino acid biosynthetic process GO:0009067 17 14 0,000 0,01116357 0,02033185 ! gas transport GO:0015669 15 14 0,000 0,01116357 0,0203217 ! pyridine nucleotide biosynthetic process GO:0019363 15 14 0,000 0,01116357 0,02031156 ! heme biosynthetic process GO:0006783 14 14 0,000 0,01116357 0,02030144 ! cerebellar cortex development GO:0021695 16 14 0,000 0,01116357 0,02029132 ! insulin secretion GO:0030073 17 14 0,000 0,01116357 0,02028122 ! tRNA binding GO:0000049 16 14 0,000 0,01116357 0,02027112 ! positive regulation of cell killing GO:0031343 16 14 0,000 0,01116357 0,02026104 ! positive regulation of protein complex assembly GO:0031334 14 14 0,000 0,01116357 0,02025096 ! G1 phase of mitotic cell cycle GO:0000080 15 14 0,000 0,01116357 0,0202409 ! phosphatidylinositol metabolic process GO:0046488 15 14 0,000 0,01116357 0,02023084 ! regulation of neuronal synaptic plasticity GO:0048168 24 14 0,000 0,01116357 0,0202208 ! MAP kinase activity GO:0004707 16 14 0,000 0,01116357 0,02021076 ! cytokine biosynthetic process GO:0042089 14 14 0,000 0,01116357 0,02020074 ! mannosyltransferase activity GO:0000030 14 14 0,000 0,01116357 0,02019072 ! isoprenoid biosynthetic process GO:0008299 17 14 0,000 0,01116357 0,02018072 ! C-C chemokine binding GO:0019957 15 14 0,000 0,01116357 0,02017072 GO:0016493|C-C chemokine receptor activity, ! cardiac muscle tissue development GO:0048738 16 14 0,000 0,01116357 0,02016074 ! complement activation, alternative pathway GO:0006957 14 14 0,000 0,01116357 0,02015076 ! response to osmotic stress GO:0006970 17 14 0,000 0,01116357 0,02014079 ! fructose metabolic process GO:0006000 15 14 0,000 0,01116357 0,02013084 ! telomeric DNA binding GO:0042162 17 14 0,000 0,01116357 0,02012089 ! monoamine transport GO:0015844 15 14 0,000 0,01116357 0,02011096 ! regulation of pathway-restricted SMAD protein phosphorylation GO:0060393 14 14 0,000 0,01116357 0,02010103 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,01116357 0,02009111 ! dendritic spine GO:0043197 15 14 0,000 0,01116357 0,02008121 ! stem cell development GO:0048864 14 14 0,000 0,01116357 0,02007131 GO:0019827|stem cell maintenance, ! regulation of alpha-beta T cell activation GO:0046634 15 14 0,000 0,01116357 0,02006142 ! regulation of insulin receptor signaling pathway GO:0046626 17 14 0,000 0,01116357 0,02005154 ! regulation of cytokine production during immune response GO:0002718 15 14 0,000 0,01116357 0,02004168 ! positive regulation of protein import into nucleus GO:0042307 16 14 0,000 0,01116357 0,02003182 ! regulation of cellular pH GO:0030641 14 14 0,000 0,01116357 0,02002197 ! regulation of monooxygenase activity GO:0032768 14 14 0,000 0,01116357 0,02001213 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,01116357 0,0200023 ! sarcoplasmic reticulum membrane GO:0033017 16 14 0,000 0,01116357 0,01999248 ! detection of biotic stimulus GO:0009595 16 14 0,000 0,01116357 0,01998267 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 16 14 0,000 0,01116357 0,01997287 ! mannosidase activity GO:0015923 19 14 0,000 0,01116357 0,01996308 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 17 14 0,000 0,01116357 0,0199533 ! negative regulation of tissue remodeling GO:0034104 16 14 0,000 0,01116357 0,01994353 ! positive regulation of bone mineralization GO:0030501 14 14 0,000 0,01116357 0,01993377 ! neuromuscular synaptic transmission GO:0007274 15 14 0,000 0,01116357 0,01992401 ! regulation of immunoglobulin production GO:0002637 15 14 0,000 0,01116357 0,01991427 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,01116357 0,01990454 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 16 14 0,000 0,01116357 0,01989482 ! fucosyltransferase activity GO:0008417 16 14 0,000 0,01116357 0,0198851 ! sperm-egg recognition GO:0035036 17 14 0,000 0,01116357 0,0198754 GO:0007339|binding of sperm to zona pellucida, ! defense response to virus GO:0051607 21 14 0,000 0,01116357 0,0198657 ! SWI/SNF-type complex GO:0070603 16 14 0,000 0,01116357 0,01985601 GO:0016514|SWI/SNF complex, ! aldo-keto reductase activity GO:0004033 15 14 0,000 0,01116357 0,01984634 ! positive regulation of translation GO:0045727 17 15 0,000 0,0119565 0,02124564 ! nuclear replication fork GO:0043596 26 15 0,000 0,0119565 0,02123529 ! transferase activity, transferring amino-acyl groups GO:0016755 15 15 0,000 0,0119565 0,02122496 ! 2'-deoxyribonucleotide metabolic process GO:0009394 16 15 0,000 0,0119565 0,02121464 GO:0019692|deoxyribose phosphate metabolic process, ! phospholipid catabolic process GO:0009395 26 15 0,000 0,0119565 0,02120432 ! endothelial cell migration GO:0043542 16 15 0,000 0,0119565 0,02119402 ! lipid phosphorylation GO:0046834 19 15 0,000 0,0119565 0,02118373 ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,0119565 0,02117344 ! response to vitamin GO:0033273 19 15 0,000 0,0119565 0,02116317 ! gene silencing by RNA GO:0031047 17 15 0,000 0,0119565 0,02115291 ! striated muscle thick filament GO:0005863 16 15 0,000 0,0119565 0,02114265 GO:0032982|myosin filament, ! cellular response to hydrogen peroxide GO:0070301 15 15 0,000 0,0119565 0,02113241 GO:0042744|hydrogen peroxide catabolic process, ! endocrine pancreas development GO:0031018 16 15 0,000 0,0119565 0,02112218 ! regulation of interleukin-2 biosynthetic process GO:0045076 15 15 0,000 0,0119565 0,02111195 ! glutamate metabolic process GO:0006536 17 15 0,000 0,0119565 0,02110174 ! pituitary gland development GO:0021983 16 15 0,000 0,0119565 0,02109154 ! cholesterol binding GO:0015485 15 15 0,000 0,0119565 0,02108134 ! NAD metabolic process GO:0019674 17 15 0,000 0,0119565 0,02107116 ! protease binding GO:0002020 20 15 0,000 0,0119565 0,02106098 ! regulation of heart rate GO:0002027 20 15 0,000 0,0119565 0,02105082 ! actin filament bundle GO:0032432 18 15 0,000 0,0119565 0,02104066 GO:0001725|stress fiber, ! Golgi cisterna GO:0031985 17 15 0,000 0,0119565 0,02103052 ! regulation of exocytosis GO:0017157 16 15 0,000 0,0119565 0,02102038 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,0119565 0,02101026 ! embryonic digit morphogenesis GO:0042733 17 15 0,000 0,0119565 0,02100014 ! positive regulation of biomineral formation GO:0070169 15 15 0,000 0,0119565 0,02099004 ! prostaglandin metabolic process GO:0006693 15 15 0,000 0,0119565 0,02097994 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 20 15 0,000 0,0119565 0,02096985 ! neuron recognition GO:0008038 18 15 0,000 0,0119565 0,02095978 ! hindbrain morphogenesis GO:0021575 18 15 0,000 0,0119565 0,02094971 ! filopodium GO:0030175 17 15 0,000 0,0119565 0,02093965 ! negative regulation of blood coagulation GO:0030195 18 15 0,000 0,0119565 0,0209296 ! folic acid and derivative metabolic process GO:0006760 15 15 0,000 0,0119565 0,02091957 ! positive regulation of neuron differentiation GO:0045666 27 15 0,000 0,0119565 0,02090954 ! peptide hormone binding GO:0017046 16 15 0,000 0,0119565 0,02089952 ! regulation of ATPase activity GO:0043462 17 15 0,000 0,0119565 0,02088951 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 16 15 0,000 0,0119565 0,02087951 ! regulation of leukocyte mediated cytotoxicity GO:0001910 21 15 0,000 0,0119565 0,02086952 ! acid-thiol ligase activity GO:0016878 16 15 0,000 0,0119565 0,02085954 ! aromatic compound biosynthetic process GO:0019438 25 15 0,000 0,0119565 0,02084957 ! positive regulation of calcium ion transport GO:0051928 20 15 0,000 0,0119565 0,02083961 ! dystrophin-associated glycoprotein complex GO:0016010 17 15 0,000 0,0119565 0,02082965 ! RNA 3'-end processing GO:0031123 16 15 0,000 0,0119565 0,02081971 ! developmental induction GO:0031128 17 15 0,000 0,0119565 0,02080978 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 17 15 0,000 0,0119565 0,02079985 ! protein import into nucleus, docking GO:0000059 15 15 0,000 0,0119565 0,02078994 ! regulation of skeletal muscle tissue development GO:0048641 18 15 0,000 0,0119565 0,02078004 ! lactation GO:0007595 17 15 0,000 0,0119565 0,02077014 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 16 15 0,000 0,0119565 0,02076025 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,0119565 0,02075038 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,0119565 0,02074051 ! double-strand break repair via homologous recombination GO:0000724 36 15 0,000 0,0119565 0,02073065 GO:0000725|recombinational repair, ! phosphatidylcholine metabolic process GO:0046470 16 15 0,000 0,0119565 0,02072081 ! regulation of cell-cell adhesion GO:0022407 18 15 0,000 0,0119565 0,02071097 ! sulfate transport GO:0008272 16 15 0,000 0,0119565 0,02070114 ! hindlimb morphogenesis GO:0035137 17 15 0,000 0,0119565 0,02069132 ! bile acid metabolic process GO:0008206 17 15 0,000 0,0119565 0,02068151 ! very-low-density lipoprotein particle GO:0034361 16 15 0,000 0,0119565 0,0206717 GO:0034385|triglyceride-rich lipoprotein particle, ! adult walking behavior GO:0007628 19 15 0,000 0,0119565 0,02066191 ! 2 iron, 2 sulfur cluster binding GO:0051537 16 15 0,000 0,0119565 0,02065213 ! heart looping GO:0001947 18 15 0,000 0,0119565 0,02064235 ! protein kinase C activity GO:0004697 17 15 0,000 0,0119565 0,02063259 ! oligodendrocyte differentiation GO:0048709 15 15 0,000 0,0119565 0,02062283 ! regulation of striated muscle contraction GO:0006942 18 15 0,000 0,0119565 0,02061309 ! pigmentation during development GO:0048066 17 15 0,000 0,0119565 0,02060335 ! cytokine metabolic process GO:0042107 15 15 0,000 0,0119565 0,02059362 ! vesicle coating GO:0006901 17 15 0,000 0,0119565 0,0205839 ! disulfide oxidoreductase activity GO:0015036 16 15 0,000 0,0119565 0,0205742 ! neutral amino acid transport GO:0015804 18 15 0,000 0,0119565 0,0205645 ! L-amino acid transport GO:0015807 16 15 0,000 0,0119565 0,0205548 ! microfilament motor activity GO:0000146 15 15 0,000 0,0119565 0,02054512 ! carbonate dehydratase activity GO:0004089 18 15 0,000 0,0119565 0,02053545 ! regulation of vasodilation GO:0042312 25 15 0,000 0,0119565 0,02052579 ! DNA replication initiation GO:0006270 15 15 0,000 0,0119565 0,02051613 ! taste receptor activity GO:0008527 15 15 0,000 0,0119565 0,02050649 ! cellular pigmentation GO:0033059 16 15 0,000 0,0119565 0,02049685 ! voltage-gated chloride channel activity GO:0005247 18 15 0,000 0,0119565 0,02048722 ! voltage-gated sodium channel activity GO:0005248 18 15 0,000 0,0119565 0,0204776 ! long-chain fatty acid transport GO:0015909 17 15 0,000 0,0119565 0,02046799 ! positive regulation of neurological system process GO:0031646 18 15 0,000 0,0119565 0,02045839 ! nerve-nerve synaptic transmission GO:0007270 17 15 0,000 0,0119565 0,0204488 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 17 15 0,000 0,0119565 0,02043922 ! ion gated channel activity GO:0022839 17 15 0,000 0,0119565 0,02042965 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 15 15 0,000 0,0119565 0,02042008 ! receptor activator activity GO:0030546 17 15 0,000 0,0119565 0,02041053 ! protein transmembrane transporter activity GO:0008320 16 15 0,000 0,0119565 0,02040098 ! negative regulation of mast cell proliferation GO:0070667 16 15 0,000 0,0119565 0,02039144 GO:0042130|negative regulation of T cell proliferation, ! acylglycerol O-acyltransferase activity GO:0016411 16 15 0,000 0,0119565 0,02038191 ! triacylglycerol lipase activity GO:0004806 16 15 0,000 0,0119565 0,02037239 ! peptide hormone processing GO:0016486 19 15 0,000 0,0119565 0,02036288 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,0119565 0,02035338 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 19 16 0,000 0,01274883 0,02169204 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,01274883 0,02168193 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 18 16 0,000 0,01274883 0,02167183 ! heterophilic cell adhesion GO:0007157 17 16 0,000 0,01274883 0,02166173 ! gamma-aminobutyric acid signaling pathway GO:0007214 17 16 0,000 0,01274883 0,02165165 ! kinesin complex GO:0005871 16 16 0,000 0,01274883 0,02164157 ! photoreceptor cell development GO:0042461 22 16 0,000 0,01274883 0,02163151 GO:0046530|photoreceptor cell differentiation, ! negative regulation of gene expression, epigenetic GO:0045814 16 16 0,000 0,01274883 0,02162145 ! mitotic chromosome condensation GO:0007076 17 16 0,000 0,01274883 0,0216114 ! centrosome cycle GO:0007098 26 16 0,000 0,01274883 0,02160136 ! negative regulation of epithelial cell proliferation GO:0050680 18 16 0,000 0,01274883 0,02159134 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 16 0,000 0,01274883 0,02158132 ! DNA duplex unwinding GO:0032508 17 16 0,000 0,01274883 0,02157131 GO:0032392|DNA geometric change, ! cerebral cortex development GO:0021987 16 16 0,000 0,01274883 0,02156131 ! lysosomal transport GO:0007041 16 16 0,000 0,01274883 0,02155132 ! transforming growth factor beta receptor activity GO:0005024 18 16 0,000 0,01274883 0,02154133 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! rough endoplasmic reticulum GO:0005791 16 16 0,000 0,01274883 0,02153136 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 16 16 0,000 0,01274883 0,0215214 ! small nucleolar ribonucleoprotein complex GO:0005732 16 16 0,000 0,01274883 0,02151144 ! myofibril assembly GO:0030239 17 16 0,000 0,01274883 0,0215015 GO:0055002|striated muscle cell development, ! G1 phase GO:0051318 17 16 0,000 0,01274883 0,02149156 ! receptor signaling complex scaffold activity GO:0030159 19 16 0,000 0,01274883 0,02148163 ! negative regulation of inflammatory response GO:0050728 17 16 0,000 0,01274883 0,02147172 ! clathrin vesicle coat GO:0030125 20 16 0,000 0,01274883 0,02146181 ! endodeoxyribonuclease activity GO:0004520 43 16 0,000 0,01274883 0,02145191 ! sphingolipid catabolic process GO:0030149 18 16 0,000 0,01274883 0,02144202 GO:0046466|membrane lipid catabolic process, ! natural killer cell activation GO:0030101 17 16 0,000 0,01274883 0,02143214 ! steroid catabolic process GO:0006706 18 16 0,000 0,01274883 0,02142227 ! branched chain family amino acid metabolic process GO:0009081 18 16 0,000 0,01274883 0,0214124 ! cell-cell recognition GO:0009988 19 16 0,000 0,01274883 0,02140255 ! somatic diversification of immune receptors GO:0002200 17 16 0,000 0,01274883 0,0213927 ! spleen development GO:0048536 19 16 0,000 0,01274883 0,02138287 ! lymphocyte homeostasis GO:0002260 17 16 0,000 0,01274883 0,02137304 ! regulation of fatty acid oxidation GO:0046320 19 16 0,000 0,01274883 0,02136322 ! neural tube closure GO:0001843 19 16 0,000 0,01274883 0,02135341 GO:0060606|tube closure, ! antigen receptor-mediated signaling pathway GO:0050851 22 16 0,000 0,01274883 0,02134362 ! regulation of glucose metabolic process GO:0010906 18 16 0,000 0,01274883 0,02133382 ! regulation of lipid catabolic process GO:0050994 18 16 0,000 0,01274883 0,02132404 ! viral genome replication GO:0019079 16 16 0,000 0,01274883 0,02131427 ! regulation of neurotransmitter transport GO:0051588 19 16 0,000 0,01274883 0,02130451 ! memory GO:0007613 18 16 0,000 0,01274883 0,02129475 ! regulation of carbohydrate biosynthetic process GO:0043255 17 16 0,000 0,01274883 0,02128501 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01274883 0,02127527 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 18 16 0,000 0,01274883 0,02126554 ! glycoprotein binding GO:0001948 19 16 0,000 0,01274883 0,02125582 ! negative regulation of endothelial cell proliferation GO:0001937 17 16 0,000 0,01274883 0,02124611 ! syntaxin binding GO:0019905 18 16 0,000 0,01274883 0,02123641 ! myosin binding GO:0017022 17 16 0,000 0,01274883 0,02122672 ! epidermis morphogenesis GO:0048730 18 16 0,000 0,01274883 0,02121703 ! fucose metabolic process GO:0006004 18 16 0,000 0,01274883 0,02120736 ! actin polymerization or depolymerization GO:0008154 18 16 0,000 0,01274883 0,02119769 ! membrane budding GO:0006900 18 16 0,000 0,01274883 0,02118804 ! preassembly of GPI anchor in ER membrane GO:0016254 18 16 0,000 0,01274883 0,02117839 ! intermediate filament cytoskeleton organization GO:0045104 16 16 0,000 0,01274883 0,02116875 ! behavioral interaction between organisms GO:0051705 19 16 0,000 0,01274883 0,02115912 ! nucleotide-excision repair, DNA gap filling GO:0006297 19 16 0,000 0,01274883 0,02114949 ! anchored to plasma membrane GO:0046658 20 16 0,000 0,01274883 0,02113988 ! calcium activated cation channel activity GO:0005227 18 16 0,000 0,01274883 0,02113028 ! DNA fragmentation involved in apoptosis GO:0006309 18 16 0,000 0,01274883 0,02112068 ! apoptotic protease activator activity GO:0016505 18 16 0,000 0,01274883 0,02111109 ! sulfuric ester hydrolase activity GO:0008484 18 16 0,000 0,01274883 0,02110151 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 18 16 0,000 0,01274883 0,02109194 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,01274883 0,02108238 ! RNA polymerase II transcription mediator activity GO:0016455 19 16 0,000 0,01274883 0,02107283 ! axoneme GO:0005930 16 16 0,000 0,01274883 0,02106329 ! negative regulation of homeostatic process GO:0032845 19 16 0,000 0,01274883 0,02105375 ! anion exchanger activity GO:0015380 17 17 0,000 0,01354057 0,02235114 ! positive regulation of hormone secretion GO:0046887 19 17 0,000 0,01354057 0,02234103 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 17 17 0,000 0,01354057 0,02233093 ! transcription from RNA polymerase III promoter GO:0006383 18 17 0,000 0,01354057 0,02232084 ! glial cell development GO:0021782 17 17 0,000 0,01354057 0,02231076 ! limbic system development GO:0021761 18 17 0,000 0,01354057 0,02230069 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 17 0,000 0,01354057 0,02229062 ! ephrin receptor activity GO:0005003 21 17 0,000 0,01354057 0,02228057 ! acetylcholine receptor activity GO:0015464 18 17 0,000 0,01354057 0,02227052 ! glutamine metabolic process GO:0006541 26 17 0,000 0,01354057 0,02226049 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 21 17 0,000 0,01354057 0,02225046 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 37 17 0,000 0,01354057 0,02224044 ! signal sequence binding GO:0005048 18 17 0,000 0,01354057 0,02223043 ! cell-substrate junction assembly GO:0007044 21 17 0,000 0,01354057 0,02222043 ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,01354057 0,02221044 ! organelle subcompartment GO:0031984 19 17 0,000 0,01354057 0,02220046 ! regulation of vasoconstriction GO:0019229 21 17 0,000 0,01354057 0,02219048 ! membrane depolarization GO:0051899 19 17 0,000 0,01354057 0,02218052 ! oogenesis GO:0048477 20 17 0,000 0,01354057 0,02217056 ! nuclear outer membrane GO:0005640 21 17 0,000 0,01354057 0,02216062 ! regulation of immunoglobulin mediated immune response GO:0002889 18 17 0,000 0,01354057 0,02215068 GO:0002712|regulation of B cell mediated immunity, ! immunoglobulin production GO:0002377 21 17 0,000 0,01354057 0,02214075 GO:0002440|production of molecular mediator of immune response, ! positive regulation of cellular carbohydrate metabolic process GO:0010676 18 17 0,000 0,01354057 0,02213083 ! positive regulation of macrophage differentiation GO:0045651 21 17 0,000 0,01354057 0,02212092 ! organic cation transport GO:0015695 17 17 0,000 0,01354057 0,02211102 ! porphyrin biosynthetic process GO:0006779 17 17 0,000 0,01354057 0,02210113 GO:0033014|tetrapyrrole biosynthetic process, ! phosphatidylinositol binding GO:0005545 21 17 0,000 0,01354057 0,02209124 ! hyaluronic acid binding GO:0005540 19 17 0,000 0,01354057 0,02208137 ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 17 0,000 0,01354057 0,0220715 ! negative regulation of coagulation GO:0050819 20 17 0,000 0,01354057 0,02206164 ! cellular monovalent inorganic cation homeostasis GO:0030004 18 17 0,000 0,01354057 0,02205179 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 17 0,000 0,01354057 0,02204195 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 17 0,000 0,01354057 0,02203212 ! negative regulation of defense response GO:0031348 19 17 0,000 0,01354057 0,0220223 ! lipid localization GO:0010876 19 17 0,000 0,01354057 0,02201249 GO:0019915|lipid storage, ! tube lumen formation GO:0035148 20 17 0,000 0,01354057 0,02200268 ! negative regulation of cytokine biosynthetic process GO:0042036 18 17 0,000 0,01354057 0,02199288 ! regulation of systemic arterial blood pressure by hormone GO:0001990 17 17 0,000 0,01354057 0,0219831 GO:0050886|endocrine process, ! MAP kinase kinase kinase activity GO:0004709 19 17 0,000 0,01354057 0,02197332 ! negative regulation of protein amino acid phosphorylation GO:0001933 19 17 0,000 0,01354057 0,02196355 ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 22 17 0,000 0,01354057 0,02195379 ! response to hexose stimulus GO:0009746 20 17 0,000 0,01354057 0,02194403 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! transmembrane receptor protein phosphatase activity GO:0019198 24 17 0,000 0,01354057 0,02193429 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 17 0,000 0,01354057 0,02192455 ! AMP binding GO:0016208 19 17 0,000 0,01354057 0,02191483 ! UDP-galactosyltransferase activity GO:0035250 19 17 0,000 0,01354057 0,02190511 ! receptor metabolic process GO:0043112 20 17 0,000 0,01354057 0,0218954 ! neurotransmitter metabolic process GO:0042133 20 17 0,000 0,01354057 0,0218857 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 23 17 0,000 0,01354057 0,021876 ! alcohol binding GO:0043178 20 17 0,000 0,01354057 0,02186632 ! T cell differentiation in the thymus GO:0033077 28 17 0,000 0,01354057 0,02185664 ! visual learning GO:0008542 31 17 0,000 0,01354057 0,02184698 ! structural constituent of eye lens GO:0005212 20 17 0,000 0,01354057 0,02183732 ! cellular amino acid derivative catabolic process GO:0042219 19 17 0,000 0,01354057 0,02182767 ! neutrophil chemotaxis GO:0030593 17 17 0,000 0,01354057 0,02181803 ! protein localization in mitochondrion GO:0070585 19 17 0,000 0,01354057 0,0218084 GO:0006626|protein targeting to mitochondrion, ! aspartic-type endopeptidase activity GO:0004190 18 17 0,000 0,01354057 0,02179877 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 19 17 0,000 0,01354057 0,02178916 ! proton-transporting ATP synthase complex GO:0045259 17 17 0,000 0,01354057 0,02177955 ! translation elongation factor activity GO:0003746 19 17 0,000 0,01354057 0,02176995 ! cilium assembly GO:0042384 18 17 0,000 0,01354057 0,02176036 ! transforming growth factor beta receptor binding GO:0005160 19 17 0,000 0,01354057 0,02175078 ! positive regulation of homeostatic process GO:0032846 23 17 0,000 0,01354057 0,0217412 ! solute:hydrogen antiporter activity GO:0015299 18 17 0,000 0,01354057 0,02173164 ! protein secretion GO:0009306 19 18 0,000 0,01433173 0,02299126 ! positive regulation of ossification GO:0045778 19 18 0,000 0,01433173 0,02298116 ! positive regulation of angiogenesis GO:0045766 19 18 0,000 0,01433173 0,02297106 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,01433173 0,02296097 GO:0005763|mitochondrial small ribosomal subunit, ! protein amino acid deacetylation GO:0006476 19 18 0,000 0,01433173 0,02295089 ! protein amino acid acetylation GO:0006473 21 18 0,000 0,01433173 0,02294082 ! positive regulation of nucleocytoplasmic transport GO:0046824 20 18 0,000 0,01433173 0,02293076 ! cAMP metabolic process GO:0046058 18 18 0,000 0,01433173 0,02292071 ! regulation of muscle cell differentiation GO:0051147 21 18 0,000 0,01433173 0,02291066 ! cornified envelope GO:0001533 22 18 0,000 0,01433173 0,02290063 ! retinoid metabolic process GO:0001523 19 18 0,000 0,01433173 0,0228906 GO:0016101|diterpenoid metabolic process, ! actomyosin GO:0042641 21 18 0,000 0,01433173 0,02288058 ! positive regulation of proteolysis GO:0045862 20 18 0,000 0,01433173 0,02287058 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 18 0,000 0,01433173 0,02286058 ! calcium-dependent protein binding GO:0048306 20 18 0,000 0,01433173 0,02285058 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 18 18 0,000 0,01433173 0,0228406 ! proton-transporting V-type ATPase complex GO:0033176 18 18 0,000 0,01433173 0,02283063 ! pyrimidine ribonucleoside metabolic process GO:0046131 23 18 0,000 0,01433173 0,02282066 ! regulation of ion transmembrane transporter activity GO:0032412 21 18 0,000 0,01433173 0,0228107 ! positive regulation of carbohydrate metabolic process GO:0045913 19 18 0,000 0,01433173 0,02280076 ! primary neural tube formation GO:0014020 21 18 0,000 0,01433173 0,02279082 ! recycling endosome GO:0055037 22 18 0,000 0,01433173 0,02278089 ! muscle cell development GO:0055001 20 18 0,000 0,01433173 0,02277096 ! kinase activator activity GO:0019209 22 18 0,000 0,01433173 0,02276105 ! positive regulation of T cell differentiation GO:0045582 28 18 0,000 0,01433173 0,02275115 ! cerebellum development GO:0021549 20 18 0,000 0,01433173 0,02274125 ! positive regulation of multicellular organism growth GO:0040018 19 18 0,000 0,01433173 0,02273136 ! somitogenesis GO:0001756 20 18 0,000 0,01433173 0,02272148 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,01433173 0,02271161 ! low-density lipoprotein binding GO:0030169 19 18 0,000 0,01433173 0,02270175 ! positive regulation of cytokine secretion GO:0050715 21 18 0,000 0,01433173 0,0226919 ! negative regulation of intracellular transport GO:0032387 20 18 0,000 0,01433173 0,02268205 ! glutamine family amino acid catabolic process GO:0009065 21 18 0,000 0,01433173 0,02267222 ! basal plasma membrane GO:0009925 21 18 0,000 0,01433173 0,02266239 GO:0045178|basal part of cell, ! vitamin D receptor binding GO:0042809 20 18 0,000 0,01433173 0,02265257 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 19 18 0,000 0,01433173 0,02264276 ! embryonic organ morphogenesis GO:0048562 22 18 0,000 0,01433173 0,02263296 ! regulation of cell killing GO:0031341 24 18 0,000 0,01433173 0,02262317 ! positive regulation of cellular catabolic process GO:0031331 20 18 0,000 0,01433173 0,02261338 ! nuclear chromosome, telomeric region GO:0000784 30 18 0,000 0,01433173 0,0226036 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 19 18 0,000 0,01433173 0,02259384 ! intra-Golgi vesicle-mediated transport GO:0006891 20 18 0,000 0,01433173 0,02258408 ! protein complex scaffold GO:0032947 22 18 0,000 0,01433173 0,02257432 ! SNAP receptor activity GO:0005484 21 18 0,000 0,01433173 0,02256458 ! dendrite development GO:0016358 22 18 0,000 0,01433173 0,02255485 ! cell differentiation in spinal cord GO:0021515 21 18 0,000 0,01433173 0,02254512 ! inactivation of MAPK activity GO:0000188 20 18 0,000 0,01433173 0,0225354 ! calmodulin-dependent protein kinase activity GO:0004683 20 18 0,000 0,01433173 0,02252569 ! D-ribose metabolic process GO:0006014 19 18 0,000 0,01433173 0,02251599 ! nuclear ubiquitin ligase complex GO:0000152 31 18 0,000 0,01433173 0,0225063 ! glucuronosyltransferase activity GO:0015020 18 18 0,000 0,01433173 0,02249662 ! coreceptor activity GO:0015026 28 18 0,000 0,01433173 0,02248694 ! response to fungus GO:0009620 18 18 0,000 0,01433173 0,02247727 ! stem cell differentiation GO:0048863 18 18 0,000 0,01433173 0,02246761 ! intermediate filament-based process GO:0045103 18 18 0,000 0,01433173 0,02245796 ! heart process GO:0003015 19 18 0,000 0,01433173 0,02244832 GO:0060047|heart contraction, ! mismatch repair GO:0006298 28 18 0,000 0,01433173 0,02243868 ! vasodilation GO:0042311 20 18 0,000 0,01433173 0,02242906 ! transport vesicle membrane GO:0030658 23 18 0,000 0,01433173 0,02241944 ! MHC protein binding GO:0042287 30 18 0,000 0,01433173 0,02240983 ! inward rectifier potassium channel activity GO:0005242 22 18 0,000 0,01433173 0,02240023 ! chloride transmembrane transporter activity GO:0015108 19 18 0,000 0,01433173 0,02239064 ! bicarbonate transmembrane transporter activity GO:0015106 18 18 0,000 0,01433173 0,02238105 ! ionotropic glutamate receptor activity GO:0004970 22 18 0,000 0,01433173 0,02237147 ! cell-cell adherens junction GO:0005913 20 18 0,000 0,01433173 0,02236191 ! negative regulation of leukocyte proliferation GO:0070664 20 18 0,000 0,01433173 0,02235235 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! ubiquitin-specific protease activity GO:0004843 19 18 0,000 0,01433173 0,02234279 ! ATP-dependent RNA helicase activity GO:0004004 28 18 0,000 0,01433173 0,02233325 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 24 19 0,000 0,01512228 0,02355512 ! pteridine and derivative metabolic process GO:0042558 29 19 0,000 0,01512228 0,02354507 ! proteasome core complex GO:0005839 20 19 0,000 0,01512228 0,02353502 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 22 19 0,000 0,01512228 0,02352499 ! anion:anion antiporter activity GO:0015301 19 19 0,000 0,01512228 0,02351496 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 24 19 0,000 0,01512228 0,02350494 ! regulation of transmembrane transporter activity GO:0022898 22 19 0,000 0,01512228 0,02349493 GO:0032409|regulation of transporter activity, ! regulation of survival gene product expression GO:0045884 23 19 0,000 0,01512228 0,02348493 ! activation of pro-apoptotic gene products GO:0008633 26 19 0,000 0,01512228 0,02347493 ! deoxyribonucleotide metabolic process GO:0009262 20 19 0,000 0,01512228 0,02346495 ! lysosome organization GO:0007040 20 19 0,000 0,01512228 0,02345497 ! cellular macromolecular complex disassembly GO:0034623 23 19 0,000 0,01512228 0,023445 ! cellular response to unfolded protein GO:0034620 21 19 0,000 0,01512228 0,02343504 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron development GO:0021954 21 19 0,000 0,01512228 0,02342509 ! threonine-type endopeptidase activity GO:0004298 20 19 0,000 0,01512228 0,02341515 GO:0070003|threonine-type peptidase activity, ! chromosome condensation GO:0030261 20 19 0,000 0,01512228 0,02340522 ! peptidyl-serine phosphorylation GO:0018105 26 19 0,000 0,01512228 0,02339529 ! regulation of endothelial cell migration GO:0010594 22 19 0,000 0,01512228 0,02338537 ! fatty acid beta-oxidation GO:0006635 21 19 0,000 0,01512228 0,02337546 ! peptide cross-linking GO:0018149 23 19 0,000 0,01512228 0,02336556 ! ventricular cardiac muscle morphogenesis GO:0055010 21 19 0,000 0,01512228 0,02335567 ! beta-catenin binding GO:0008013 23 19 0,000 0,01512228 0,02334579 ! positive regulation of locomotion GO:0040017 21 19 0,000 0,01512228 0,02333591 GO:0050921|positive regulation of chemotaxis, ! cell projection membrane GO:0031253 21 19 0,000 0,01512228 0,02332604 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,01512228 0,02331618 ! trans-Golgi network transport vesicle GO:0030140 26 19 0,000 0,01512228 0,02330633 ! sphingolipid biosynthetic process GO:0030148 20 19 0,000 0,01512228 0,02329649 ! vitamin transport GO:0051180 21 19 0,000 0,01512228 0,02328666 ! positive regulation of osteoblast differentiation GO:0045669 22 19 0,000 0,01512228 0,02327683 ! terpenoid metabolic process GO:0006721 20 19 0,000 0,01512228 0,02326701 ! leukotriene biosynthetic process GO:0019370 20 19 0,000 0,01512228 0,02325721 GO:0043450|alkene biosynthetic process, ! nerve development GO:0021675 24 19 0,000 0,01512228 0,02324741 ! retinoid binding GO:0005501 19 19 0,000 0,01512228 0,02323761 GO:0019840|isoprenoid binding, ! regulation of amine transport GO:0051952 23 19 0,000 0,01512228 0,02322783 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 22 19 0,000 0,01512228 0,02321805 ! histone deacetylase activity GO:0004407 20 19 0,000 0,01512228 0,02320828 GO:0033558|protein deacetylase activity, ! regulation of microtubule polymerization or depolymerization GO:0031110 21 19 0,000 0,01512228 0,02319853 ! gluconeogenesis GO:0006094 23 19 0,000 0,01512228 0,02318877 ! post-Golgi vesicle-mediated transport GO:0006892 23 19 0,000 0,01512228 0,02317903 ! microtubule-based transport GO:0010970 20 19 0,000 0,01512228 0,0231693 ! superoxide metabolic process GO:0006801 21 19 0,000 0,01512228 0,02315957 ! C21-steroid hormone metabolic process GO:0008207 20 19 0,000 0,01512228 0,02314985 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,01512228 0,02314014 GO:0006479|protein amino acid methylation, ! L-ascorbic acid binding GO:0031418 19 19 0,000 0,01512228 0,02313044 ! regulation of DNA recombination GO:0000018 38 19 0,000 0,01512228 0,02312074 ! photoreceptor cell maintenance GO:0045494 23 19 0,000 0,01512228 0,02311106 ! positive regulation of cytoskeleton organization GO:0051495 22 19 0,000 0,01512228 0,02310138 ! acetylcholine binding GO:0042166 20 19 0,000 0,01512228 0,02309171 ! heme metabolic process GO:0042168 20 19 0,000 0,01512228 0,02308205 ! SH2 domain binding GO:0042169 25 19 0,000 0,01512228 0,02307239 ! neurotransmitter:sodium symporter activity GO:0005328 21 19 0,000 0,01512228 0,02306275 ! negative regulation of protein catabolic process GO:0042177 19 19 0,000 0,01512228 0,02305311 ! carbohydrate kinase activity GO:0019200 20 19 0,000 0,01512228 0,02304348 ! RNA methyltransferase activity GO:0008173 19 19 0,000 0,01512228 0,02303386 ! RNA-dependent ATPase activity GO:0008186 29 19 0,000 0,01512228 0,02302425 ! body fluid secretion GO:0007589 21 19 0,000 0,01512228 0,02301464 ! neuropeptide hormone activity GO:0005184 25 19 0,000 0,01512228 0,02300504 ! secretory granule membrane GO:0030667 21 19 0,000 0,01512228 0,02299545 ! extracellular-glutamate-gated ion channel activity GO:0005234 23 19 0,000 0,01512228 0,02298587 ! ribonucleoprotein binding GO:0043021 20 19 0,000 0,01512228 0,0229763 ! peptidase activator activity GO:0016504 21 19 0,000 0,01512228 0,02296673 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,01512228 0,02295718 ! small conjugating protein-specific protease activity GO:0019783 21 19 0,000 0,01512228 0,02294763 ! regulation of BMP signaling pathway GO:0030510 20 19 0,000 0,01512228 0,02293808 ! sialyltransferase activity GO:0008373 31 19 0,000 0,01512228 0,02292855 ! ATP-dependent DNA helicase activity GO:0004003 30 19 0,000 0,01512228 0,02291902 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 23 20 0,000 0,01591225 0,02410627 ! regulation of anti-apoptosis GO:0045767 20 20 0,000 0,01591225 0,02409626 ! reciprocal meiotic recombination GO:0007131 40 20 0,000 0,01591225 0,02408626 ! protein amino acid ADP-ribosylation GO:0006471 23 20 0,000 0,01591225 0,02407627 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 30 20 0,000 0,01591225 0,02406629 ! retina development in camera-type eye GO:0060041 24 20 0,000 0,01591225 0,02405632 ! negative regulation of lipid metabolic process GO:0045833 34 20 0,000 0,01591225 0,02404635 ! ovarian follicle development GO:0001541 21 20 0,000 0,01591225 0,02403639 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 33 20 0,000 0,01591225 0,02402644 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 21 20 0,000 0,01591225 0,0240165 ! hydrogen peroxide metabolic process GO:0042743 20 20 0,000 0,01591225 0,02400657 ! diencephalon development GO:0021536 22 20 0,000 0,01591225 0,02399665 ! nuclear inner membrane GO:0005637 21 20 0,000 0,01591225 0,02398673 ! regulation of lipid transport GO:0032368 22 20 0,000 0,01591225 0,02397682 ! response to glucocorticoid stimulus GO:0051384 22 20 0,000 0,01591225 0,02396692 ! glutathione metabolic process GO:0006749 21 20 0,000 0,01591225 0,02395703 ! transcriptional repressor complex GO:0017053 23 20 0,000 0,01591225 0,02394715 ! vitamin A metabolic process GO:0006776 20 20 0,000 0,01591225 0,02393727 ! positive regulation of lymphocyte differentiation GO:0045621 30 20 0,000 0,01591225 0,02392741 ! negative regulation of cytokine production GO:0001818 23 20 0,000 0,01591225 0,02391755 ! phosphorus-oxygen lyase activity GO:0016849 21 20 0,000 0,01591225 0,0239077 ! peptide hormone secretion GO:0030072 25 20 0,000 0,01591225 0,02389786 GO:0002790|peptide secretion, ! actin filament-based movement GO:0030048 22 20 0,000 0,01591225 0,02388802 ! Rab GTPase binding GO:0017137 22 20 0,000 0,01591225 0,02387819 ! initiation of viral infection GO:0019059 22 20 0,000 0,01591225 0,02386838 ! voltage-gated anion channel activity GO:0008308 23 20 0,000 0,01591225 0,02385857 ! heterochromatin GO:0000792 20 20 0,000 0,01591225 0,02384876 ! aminoglycan catabolic process GO:0006026 22 20 0,000 0,01591225 0,02383897 ! glycosaminoglycan biosynthetic process GO:0006024 21 20 0,000 0,01591225 0,02382918 ! regulation of chemotaxis GO:0050920 22 20 0,000 0,01591225 0,02381941 ! calcium-independent cell-cell adhesion GO:0016338 27 20 0,000 0,01591225 0,02380964 ! high-density lipoprotein particle GO:0034364 30 20 0,000 0,01591225 0,02379987 ! visual behavior GO:0007632 34 20 0,000 0,01591225 0,02379012 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 23 20 0,000 0,01591225 0,02378037 ! immune response-activating cell surface receptor signaling pathway GO:0002429 27 20 0,000 0,01591225 0,02377064 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of nitric oxide biosynthetic process GO:0045428 21 20 0,000 0,01591225 0,0237609 ! vesicle docking during exocytosis GO:0006904 21 20 0,000 0,01591225 0,02375118 ! cell structure disassembly during apoptosis GO:0006921 31 20 0,000 0,01591225 0,02374147 ! nucleotide kinase activity GO:0019201 26 20 0,000 0,01591225 0,02373176 ! rRNA binding GO:0019843 22 20 0,000 0,01591225 0,02372206 ! cytolysis GO:0019835 22 20 0,000 0,01591225 0,02371237 ! renal system process GO:0003014 22 20 0,000 0,01591225 0,02370269 ! specific transcriptional repressor activity GO:0016566 23 20 0,000 0,01591225 0,02369302 ! fatty acid transport GO:0015908 23 20 0,000 0,01591225 0,02368335 ! transaminase activity GO:0008483 22 20 0,000 0,01591225 0,02367369 ! activation of JUN kinase activity GO:0007257 22 20 0,000 0,01591225 0,02366404 ! collagen catabolic process GO:0030574 21 20 0,000 0,01591225 0,0236544 ! microvillus GO:0005902 25 20 0,000 0,01591225 0,02364476 ! tumor necrosis factor receptor binding GO:0005164 22 20 0,000 0,01591225 0,02363513 ! connexon complex GO:0005922 23 20 0,000 0,01591225 0,02362552 ! positive regulation of DNA replication GO:0045740 27 21 0,000 0,01670163 0,02478744 ! positive regulation of protein catabolic process GO:0045732 23 21 0,000 0,01670163 0,02477736 ! translational initiation GO:0006413 21 21 0,000 0,01670163 0,02476729 ! NF-kappaB binding GO:0051059 31 21 0,000 0,01670163 0,02475723 ! heterotrimeric G-protein complex GO:0005834 23 21 0,000 0,01670163 0,02474717 ! positive regulation of bone remodeling GO:0046852 22 21 0,000 0,01670163 0,02473712 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 21 0,000 0,01670163 0,02472708 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! transition metal ion transmembrane transporter activity GO:0046915 25 21 0,000 0,01670163 0,02471705 ! glutathione transferase activity GO:0004364 21 21 0,000 0,01670163 0,02470703 ! voltage-gated calcium channel complex GO:0005891 28 21 0,000 0,01670163 0,02469701 ! glutamate signaling pathway GO:0007215 23 21 0,000 0,01670163 0,02468701 ! regeneration GO:0031099 24 21 0,000 0,01670163 0,02467701 ! MHC class I protein complex GO:0042612 31 21 0,000 0,01670163 0,02466702 ! cellular response to starvation GO:0009267 22 21 0,000 0,01670163 0,02465703 ! peroxisome organization GO:0007031 22 21 0,000 0,01670163 0,02464706 ! vacuole organization GO:0007033 23 21 0,000 0,01670163 0,02463709 ! apoptotic nuclear changes GO:0030262 24 21 0,000 0,01670163 0,02462713 ! response to lipopolysaccharide GO:0032496 31 21 0,000 0,01670163 0,02461718 ! neural crest cell development GO:0014032 24 21 0,000 0,01670163 0,02460724 GO:0014033|neural crest cell differentiation, ! regulation of protein binding GO:0043393 25 21 0,000 0,01670163 0,02459731 ! nucleobase metabolic process GO:0009112 23 21 0,000 0,01670163 0,02458738 ! regulation of steroid metabolic process GO:0019218 23 21 0,000 0,01670163 0,02457746 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,01670163 0,02456755 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! monocarboxylic acid transmembrane transporter activity GO:0008028 25 21 0,000 0,01670163 0,02455765 ! pallium development GO:0021543 22 21 0,000 0,01670163 0,02454776 ! synaptic vesicle transport GO:0048489 25 21 0,000 0,01670163 0,02453787 ! negative regulation of Wnt receptor signaling pathway GO:0030178 22 21 0,000 0,01670163 0,02452799 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 21 0,000 0,01670163 0,02451812 ! leukocyte homeostasis GO:0001776 22 21 0,000 0,01670163 0,02450826 ! negative regulation of neuron differentiation GO:0045665 22 21 0,000 0,01670163 0,0244984 ! cyclase activity GO:0009975 22 21 0,000 0,01670163 0,02448856 ! aspartate family amino acid metabolic process GO:0009066 24 21 0,000 0,01670163 0,02447872 ! gut development GO:0048565 23 21 0,000 0,01670163 0,02446889 ! calcium-dependent phospholipid binding GO:0005544 22 21 0,000 0,01670163 0,02445907 ! negative regulation of T cell activation GO:0050868 23 21 0,000 0,01670163 0,02444925 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,01670163 0,02443944 ! cortical actin cytoskeleton GO:0030864 21 21 0,000 0,01670163 0,02442964 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,01670163 0,02441985 ! membrane lipid biosynthetic process GO:0046467 22 21 0,000 0,01670163 0,02441007 ! nucleotide-excision repair, DNA damage removal GO:0000718 22 21 0,000 0,01670163 0,02440029 ! axis specification GO:0009798 25 21 0,000 0,01670163 0,02439053 ! response to alkaloid GO:0043279 27 21 0,000 0,01670163 0,02438076 ! 4 iron, 4 sulfur cluster binding GO:0051539 24 21 0,000 0,01670163 0,02437101 ! response to ethanol GO:0045471 28 21 0,000 0,01670163 0,02436127 ! response to carbohydrate stimulus GO:0009743 24 21 0,000 0,01670163 0,02435153 ! smooth muscle contraction GO:0006939 25 21 0,000 0,01670163 0,0243418 ! ubiquitin binding GO:0043130 25 21 0,000 0,01670163 0,02433208 ! vesicle targeting GO:0006903 22 21 0,000 0,01670163 0,02432237 ! phospholipase A2 activity GO:0004623 32 21 0,000 0,01670163 0,02431266 ! SNARE binding GO:0000149 24 21 0,000 0,01670163 0,02430296 ! interaction with host GO:0051701 26 21 0,000 0,01670163 0,02429327 ! positive regulation of myeloid leukocyte differentiation GO:0002763 26 21 0,000 0,01670163 0,02428359 ! lymphocyte proliferation GO:0046651 24 21 0,000 0,01670163 0,02427392 ! regulation of tumor necrosis factor production GO:0032680 24 21 0,000 0,01670163 0,02426425 ! regulation of interleukin-2 production GO:0032663 21 21 0,000 0,01670163 0,02425459 ! negative regulation of angiogenesis GO:0016525 23 21 0,000 0,01670163 0,02424494 ! cell-cell junction organization GO:0045216 24 21 0,000 0,01670163 0,02423529 ! single-stranded RNA binding GO:0003727 22 21 0,000 0,01670163 0,02422566 ! cyclic nucleotide binding GO:0030551 25 21 0,000 0,01670163 0,02421603 ! caveola GO:0005901 25 21 0,000 0,01670163 0,02420641 ! water-soluble vitamin biosynthetic process GO:0042364 23 21 0,000 0,01670163 0,0241968 ! insulin receptor binding GO:0005158 25 21 0,000 0,01670163 0,02418719 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,01670163 0,02417759 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,01670163 0,024168 ! mRNA export from nucleus GO:0006406 26 22 0,000 0,01749041 0,02529937 ! metencephalon development GO:0022037 25 22 0,000 0,01749041 0,02528934 ! regulation of interferon-gamma production GO:0032649 25 22 0,000 0,01749041 0,02527932 ! hormone secretion GO:0046879 28 22 0,000 0,01749041 0,02526931 ! vesicle docking GO:0048278 24 22 0,000 0,01749041 0,02525931 ! muscle myosin complex GO:0005859 23 22 0,000 0,01749041 0,02524931 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 24 22 0,000 0,01749041 0,02523933 ! actomyosin structure organization GO:0031032 24 22 0,000 0,01749041 0,02522935 ! microtubule organizing center organization GO:0031023 33 22 0,000 0,01749041 0,02521937 GO:0051297|centrosome organization, ! positive regulation of innate immune response GO:0045089 23 22 0,000 0,01749041 0,02520941 ! sperm motility GO:0030317 23 22 0,000 0,01749041 0,02519945 ! potassium channel regulator activity GO:0015459 29 22 0,000 0,01749041 0,02518951 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 24 22 0,000 0,01749041 0,02517956 ! vacuolar transport GO:0007034 22 22 0,000 0,01749041 0,02516963 ! oxidoreductase activity, acting on heme group of donors GO:0016675 23 22 0,000 0,01749041 0,02515971 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! central nervous system neuron differentiation GO:0021953 24 22 0,000 0,01749041 0,02514979 ! cellular response to reactive oxygen species GO:0034614 26 22 0,000 0,01749041 0,02513988 ! purine ribonucleoside metabolic process GO:0046128 24 22 0,000 0,01749041 0,02512998 GO:0042278|purine nucleoside metabolic process, ! G-protein chemoattractant receptor activity GO:0001637 24 22 0,000 0,01749041 0,02512009 GO:0004950|chemokine receptor activity, ! response to corticosteroid stimulus GO:0031960 25 22 0,000 0,01749041 0,0251102 ! PML body GO:0016605 25 22 0,000 0,01749041 0,02510032 ! barbed-end actin filament capping GO:0051016 24 22 0,000 0,01749041 0,02509045 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 27 22 0,000 0,01749041 0,02508059 ! regulation of foam cell differentiation GO:0010743 28 22 0,000 0,01749041 0,02507073 ! cyclic nucleotide biosynthetic process GO:0009190 23 22 0,000 0,01749041 0,02506089 ! leukotriene metabolic process GO:0006691 23 22 0,000 0,01749041 0,02505105 ! glycosphingolipid metabolic process GO:0006687 23 22 0,000 0,01749041 0,02504122 ! deacetylase activity GO:0019213 23 22 0,000 0,01749041 0,02503139 ! pentose metabolic process GO:0019321 23 22 0,000 0,01749041 0,02502157 ! collagen fibril organization GO:0030199 32 22 0,000 0,01749041 0,02501177 ! regulation of response to biotic stimulus GO:0002831 33 22 0,000 0,01749041 0,02500197 ! positive regulation of adaptive immune response GO:0002821 22 22 0,000 0,01749041 0,02499217 ! peptidyl-serine modification GO:0018209 30 22 0,000 0,01749041 0,02498239 ! DNA-directed RNA polymerase complex GO:0000428 23 22 0,000 0,01749041 0,02497261 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 32 22 0,000 0,01749041 0,02496284 ! positive regulation of behavior GO:0048520 24 22 0,000 0,01749041 0,02495308 ! regulation of generation of precursor metabolites and energy GO:0043467 25 22 0,000 0,01749041 0,02494332 ! aromatic compound catabolic process GO:0019439 23 22 0,000 0,01749041 0,02493357 ! embryonic epithelial tube formation GO:0001838 25 22 0,000 0,01749041 0,02492383 GO:0001841|neural tube formation, ! telomere organization GO:0032200 43 22 0,000 0,01749041 0,0249141 GO:0000723|telomere maintenance, ! acetyl-CoA catabolic process GO:0046356 24 22 0,000 0,01749041 0,02490438 GO:0006099|tricarboxylic acid cycle, ! protein tetramerization GO:0051262 25 22 0,000 0,01749041 0,02489466 ! DNA catabolic process, endonucleolytic GO:0000737 24 22 0,000 0,01749041 0,02488495 ! glycerol metabolic process GO:0006071 24 22 0,000 0,01749041 0,02487525 ! cellular component assembly involved in morphogenesis GO:0010927 23 22 0,000 0,01749041 0,02486556 ! cellular iron ion homeostasis GO:0006879 25 22 0,000 0,01749041 0,02485587 ! aminoglycan biosynthetic process GO:0006023 23 22 0,000 0,01749041 0,02484619 ! positive regulation of JAK-STAT cascade GO:0046427 25 22 0,000 0,01749041 0,02483652 ! sterol binding GO:0032934 24 22 0,000 0,01749041 0,02482685 ! calcium-dependent cell-cell adhesion GO:0016339 23 22 0,000 0,01749041 0,0248172 ! digestive system process GO:0022600 25 22 0,000 0,01749041 0,02480755 ! neurotransmitter transporter activity GO:0005326 24 22 0,000 0,01749041 0,02479791 ! organic acid:sodium symporter activity GO:0005343 25 22 0,000 0,01749041 0,02478827 ! nonmotile primary cilium GO:0031513 24 22 0,000 0,01749041 0,02477865 ! negative regulation of myeloid leukocyte differentiation GO:0002762 26 22 0,000 0,01749041 0,02476903 ! base-excision repair GO:0006284 33 22 0,000 0,01749041 0,02475942 ! regulation of chromosome organization GO:0033044 27 22 0,000 0,01749041 0,02474981 ! DNA modification GO:0006304 25 22 0,000 0,01749041 0,02474022 ! detection of chemical stimulus GO:0009593 23 22 0,000 0,01749041 0,02473063 ! positive regulation of tissue remodeling GO:0034105 23 22 0,000 0,01749041 0,02472104 ! GABA-A receptor activity GO:0004890 27 22 0,000 0,01749041 0,02471147 ! response to cytokine stimulus GO:0034097 25 22 0,000 0,01749041 0,0247019 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 24 22 0,000 0,01749041 0,02469234 ! pyrimidine nucleoside metabolic process GO:0006213 27 22 0,000 0,01749041 0,02468279 ! phosphoprotein phosphatase inhibitor activity GO:0004864 25 22 0,000 0,01749041 0,02467325 ! solute:cation antiporter activity GO:0015298 23 22 0,000 0,01749041 0,02466371 ! regulation of transmembrane transport GO:0034762 28 23 0,000 0,0182786 0,0257652 ! protein amino acid O-linked glycosylation GO:0006493 28 23 0,000 0,0182786 0,02575525 ! leukocyte adhesion GO:0007159 26 23 0,000 0,0182786 0,02574531 ! dicarboxylic acid metabolic process GO:0043648 27 23 0,000 0,0182786 0,02573537 ! odontogenesis of dentine-containing tooth GO:0042475 26 23 0,000 0,0182786 0,02572544 ! positive regulation of endocytosis GO:0045807 25 23 0,000 0,0182786 0,02571552 ! mitochondrial membrane organization GO:0007006 25 23 0,000 0,0182786 0,02570561 ! ureteric bud development GO:0001657 24 23 0,000 0,0182786 0,0256957 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 27 23 0,000 0,0182786 0,0256858 ! regulation of insulin secretion GO:0050796 27 23 0,000 0,0182786 0,02567591 ! vitamin biosynthetic process GO:0009110 25 23 0,000 0,0182786 0,02566603 ! negative regulation of neurogenesis GO:0050768 29 23 0,000 0,0182786 0,02565615 ! cholesterol biosynthetic process GO:0006695 29 23 0,000 0,0182786 0,02564629 ! deaminase activity GO:0019239 24 23 0,000 0,0182786 0,02563643 ! sensory perception of pain GO:0019233 26 23 0,000 0,0182786 0,02562657 ! lipid kinase activity GO:0001727 26 23 0,000 0,0182786 0,02561673 ! platelet activation GO:0030168 27 23 0,000 0,0182786 0,02560689 ! proteoglycan biosynthetic process GO:0030166 24 23 0,000 0,0182786 0,02559706 ! positive regulation of intracellular transport GO:0032388 26 23 0,000 0,0182786 0,02558724 ! regulation of blood coagulation GO:0030193 26 23 0,000 0,0182786 0,02557742 ! regulation of cytokine secretion GO:0050707 27 23 0,000 0,0182786 0,02556762 ! fat-soluble vitamin metabolic process GO:0006775 23 23 0,000 0,0182786 0,02555782 ! cellular alkene metabolic process GO:0043449 24 23 0,000 0,0182786 0,02554803 ! aromatic amino acid family metabolic process GO:0009072 25 23 0,000 0,0182786 0,02553824 ! cell surface binding GO:0043498 28 23 0,000 0,0182786 0,02552846 ! porphyrin metabolic process GO:0006778 24 23 0,000 0,0182786 0,02551869 GO:0033013|tetrapyrrole metabolic process, ! ligase activity, forming carbon-sulfur bonds GO:0016877 24 23 0,000 0,0182786 0,02550893 ! regulation of glucose import GO:0046324 28 23 0,000 0,0182786 0,02549918 ! insulin-like growth factor binding GO:0005520 27 23 0,000 0,0182786 0,02548943 ! alditol metabolic process GO:0019400 25 23 0,000 0,0182786 0,02547969 ! positive regulation of JUN kinase activity GO:0043507 25 23 0,000 0,0182786 0,02546996 ! pyruvate metabolic process GO:0006090 27 23 0,000 0,0182786 0,02546023 ! zinc ion transport GO:0006829 26 23 0,000 0,0182786 0,02545051 ! N-acetylglucosamine metabolic process GO:0006044 26 23 0,000 0,0182786 0,0254408 ! antigen processing and presentation of peptide antigen GO:0048002 30 23 0,000 0,0182786 0,0254311 ! sex determination GO:0007530 25 23 0,000 0,0182786 0,02542141 ! phosphate binding GO:0042301 25 23 0,000 0,0182786 0,02541172 ! positive regulation of leukocyte mediated immunity GO:0002705 24 23 0,000 0,0182786 0,02540204 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of interleukin-6 production GO:0032675 26 23 0,000 0,0182786 0,02539236 ! nuclear-transcribed mRNA catabolic process GO:0000956 26 23 0,000 0,0182786 0,0253827 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 28 23 0,000 0,0182786 0,02537304 ! ubiquitin protein ligase binding GO:0031625 24 23 0,000 0,0182786 0,02536339 ! positive regulation of nuclear division GO:0051785 35 23 0,000 0,0182786 0,02535374 GO:0045840|positive regulation of mitosis, ! synaptogenesis GO:0007416 25 23 0,000 0,0182786 0,02534411 ! regulation of bone mineralization GO:0030500 23 23 0,000 0,0182786 0,02533448 ! neurotransmitter secretion GO:0007269 26 23 0,000 0,0182786 0,02532486 ! ethanolamine and derivative metabolic process GO:0042439 34 23 0,000 0,0182786 0,02531524 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 25 23 0,000 0,0182786 0,02530563 ! leukocyte proliferation GO:0070661 26 23 0,000 0,0182786 0,02529603 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 24 23 0,000 0,0182786 0,02528644 ! growth cone GO:0030426 27 24 0,000 0,01906621 0,02636601 ! oligosaccharide metabolic process GO:0009311 29 24 0,000 0,01906621 0,02635602 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,01906621 0,02634603 ! pancreas development GO:0031016 27 24 0,000 0,01906621 0,02633606 ! calcium channel complex GO:0034704 31 24 0,000 0,01906621 0,02632609 ! coenzyme catabolic process GO:0009109 26 24 0,000 0,01906621 0,02631613 ! negative regulation of cell development GO:0010721 30 24 0,000 0,01906621 0,02630617 ! cardiac muscle tissue morphogenesis GO:0055008 27 24 0,000 0,01906621 0,02629623 GO:0060415|muscle tissue morphogenesis, ! phosphatase inhibitor activity GO:0019212 27 24 0,000 0,01906621 0,02628629 ! regulation of oxidoreductase activity GO:0051341 24 24 0,000 0,01906621 0,02627636 ! RNA splicing factor activity, transesterification mechanism GO:0031202 25 24 0,000 0,01906621 0,02626644 ! Rho GTPase binding GO:0017048 36 24 0,000 0,01906621 0,02625652 ! regulation of glucose transport GO:0010827 29 24 0,000 0,01906621 0,02624661 ! serine family amino acid metabolic process GO:0009069 27 24 0,000 0,01906621 0,02623671 ! intramolecular transferase activity GO:0016866 26 24 0,000 0,01906621 0,02622682 ! phosphoinositide phospholipase C activity GO:0004435 28 24 0,000 0,01906621 0,02621693 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! Z disc GO:0030018 27 24 0,000 0,01906621 0,02620705 ! protein stabilization GO:0050821 24 24 0,000 0,01906621 0,02619718 ! protein import into nucleus, translocation GO:0000060 27 24 0,000 0,01906621 0,02618732 ! embryonic pattern specification GO:0009880 29 24 0,000 0,01906621 0,02617746 ! negative regulation of actin filament depolymerization GO:0030835 26 24 0,000 0,01906621 0,02616762 ! RNA polymerase complex GO:0030880 25 24 0,000 0,01906621 0,02615777 ! cellular polysaccharide biosynthetic process GO:0033692 24 24 0,000 0,01906621 0,02614794 ! glucosamine metabolic process GO:0006041 27 24 0,000 0,01906621 0,02613811 ! small conjugating protein binding GO:0032182 29 24 0,000 0,01906621 0,0261283 ! regulation of transcription factor import into nucleus GO:0042990 26 24 0,000 0,01906621 0,02611848 ! chemokine binding GO:0019956 26 24 0,000 0,01906621 0,02610868 ! catechol metabolic process GO:0009712 29 24 0,000 0,01906621 0,02609888 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of smooth muscle contraction GO:0006940 28 24 0,000 0,01906621 0,02608909 ! NAD+ ADP-ribosyltransferase activity GO:0003950 26 24 0,000 0,01906621 0,02607931 ! multicellular organismal response to stress GO:0033555 27 24 0,000 0,01906621 0,02606954 ! cell aging GO:0007569 47 24 0,000 0,01906621 0,02605977 ! immune response-activating signal transduction GO:0002757 31 24 0,000 0,01906621 0,02605001 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 24 0,000 0,01906621 0,02604026 ! fibroblast growth factor receptor signaling pathway GO:0008543 27 24 0,000 0,01906621 0,02603051 ! voltage-gated calcium channel activity GO:0005245 31 24 0,000 0,01906621 0,02602077 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 29 24 0,000 0,01906621 0,02601104 ! metallocarboxypeptidase activity GO:0004181 24 24 0,000 0,01906621 0,02600132 ! caspase regulator activity GO:0043028 26 24 0,000 0,01906621 0,0259916 ! 3'-5' exonuclease activity GO:0008408 43 24 0,000 0,01906621 0,02598189 ! small nuclear ribonucleoprotein complex GO:0030532 24 24 0,000 0,01906621 0,02597219 ! selenium binding GO:0008430 24 24 0,000 0,01906621 0,02596249 ! spindle pole GO:0000922 35 24 0,000 0,01906621 0,02595281 ! Rho GTPase activator activity GO:0005100 28 24 0,000 0,01906621 0,02594313 ! site of polarized growth GO:0030427 28 25 0,000 0,01985322 0,02700393 ! phenol metabolic process GO:0018958 31 25 0,000 0,01985322 0,02699387 ! regulation of lipid biosynthetic process GO:0046890 35 25 0,000 0,01985322 0,02698381 ! protein amino acid acylation GO:0043543 28 25 0,000 0,01985322 0,02697376 ! aromatase activity GO:0070330 28 25 0,000 0,01985322 0,02696372 ! cholesterol homeostasis GO:0042632 27 25 0,000 0,01985322 0,02695368 GO:0055092|sterol homeostasis, ! positive regulation of epithelial cell proliferation GO:0050679 29 25 0,000 0,01985322 0,02694366 ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 29 25 0,000 0,01985322 0,02693364 ! response to starvation GO:0042594 26 25 0,000 0,01985322 0,02692362 ! dynein complex GO:0030286 28 25 0,000 0,01985322 0,02691362 ! regulation of behavior GO:0050795 27 25 0,000 0,01985322 0,02690362 ! regulation of biomineral formation GO:0070167 25 25 0,000 0,01985322 0,02689363 ! hexose biosynthetic process GO:0019319 31 25 0,000 0,01985322 0,02688365 ! group transfer coenzyme metabolic process GO:0006752 25 25 0,000 0,01985322 0,02687367 ! hormone transport GO:0009914 31 25 0,000 0,01985322 0,02686371 ! response to molecule of bacterial origin GO:0002237 35 25 0,000 0,01985322 0,02685374 ! cell adhesion molecule binding GO:0050839 29 25 0,000 0,01985322 0,02684379 ! regulation of coagulation GO:0050818 28 25 0,000 0,01985322 0,02683385 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,01985322 0,02682391 ! myeloid leukocyte differentiation GO:0002573 28 25 0,000 0,01985322 0,02681398 ! acetyl-CoA metabolic process GO:0006084 27 25 0,000 0,01985322 0,02680405 ! chromosome, telomeric region GO:0000781 38 25 0,000 0,01985322 0,02679414 ! molting cycle process GO:0022404 28 25 0,000 0,01985322 0,02678423 GO:0022405|hair cycle process, GO:0001942|hair follicle development, ! collagen metabolic process GO:0032963 26 25 0,000 0,01985322 0,02677433 ! xenobiotic metabolic process GO:0006805 27 25 0,000 0,01985322 0,02676443 ! phototransduction GO:0007602 27 25 0,000 0,01985322 0,02675454 ! negative regulation of response to external stimulus GO:0032102 30 25 0,000 0,01985322 0,02674466 ! regulation of endothelial cell proliferation GO:0001936 29 25 0,000 0,01985322 0,02673479 ! protein phosphatase binding GO:0019903 27 25 0,000 0,01985322 0,02672493 ! negative regulation of DNA replication GO:0008156 31 25 0,000 0,01985322 0,02671507 ! multicellular organismal catabolic process GO:0044243 27 25 0,000 0,01985322 0,02670522 ! autophagy GO:0006914 28 25 0,000 0,01985322 0,02669537 ! steroid dehydrogenase activity GO:0016229 27 25 0,000 0,01985322 0,02668554 ! response to ionizing radiation GO:0010212 37 25 0,000 0,01985322 0,02667571 ! DNA-directed DNA polymerase activity GO:0003887 30 25 0,000 0,01985322 0,02666589 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 31 26 0,000 0,02063965 0,02771197 ! epidermal growth factor receptor signaling pathway GO:0007173 32 26 0,000 0,02063965 0,02770178 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 29 26 0,000 0,02063965 0,02769159 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 26 0,000 0,02063965 0,02768141 ! positive regulation of lipid metabolic process GO:0045834 27 26 0,000 0,02063965 0,02767123 ! hair cycle GO:0042633 29 26 0,000 0,02063965 0,02766107 GO:0042303|molting cycle, ! thyroid hormone receptor binding GO:0046966 30 26 0,000 0,02063965 0,02765091 ! polysaccharide catabolic process GO:0000272 39 26 0,000 0,02063965 0,02764076 ! peptidyl-tyrosine phosphorylation GO:0018108 30 26 0,000 0,02063965 0,02763061 ! early endosome membrane GO:0031901 31 26 0,000 0,02063965 0,02762048 ! negative regulation of protein kinase cascade GO:0010741 40 26 0,000 0,02063965 0,02761035 ! iron ion homeostasis GO:0055072 29 26 0,000 0,02063965 0,02760023 ! glycolipid metabolic process GO:0006664 36 26 0,000 0,02063965 0,02759012 ! GABA receptor activity GO:0016917 31 26 0,000 0,02063965 0,02758001 ! PDZ domain binding GO:0030165 28 26 0,000 0,02063965 0,02756991 ! positive regulation of protein secretion GO:0050714 29 26 0,000 0,02063965 0,02755982 ! regulation of cellular carbohydrate metabolic process GO:0010675 29 26 0,000 0,02063965 0,02754973 ! AP-type membrane coat adaptor complex GO:0030119 30 26 0,000 0,02063965 0,02753966 GO:0030131|clathrin adaptor complex, ! neuromuscular process controlling balance GO:0050885 32 26 0,000 0,02063965 0,02752959 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 45 26 0,000 0,02063965 0,02751953 ! fatty acid binding GO:0005504 28 26 0,000 0,02063965 0,02750947 ! blastocyst development GO:0001824 27 26 0,000 0,02063965 0,02749942 ! regulation of JUN kinase activity GO:0043506 28 26 0,000 0,02063965 0,02748938 ! lysine N-acetyltransferase activity GO:0004468 29 26 0,000 0,02063965 0,02747935 GO:0004402|histone acetyltransferase activity, ! negative regulation of protein polymerization GO:0032272 37 26 0,000 0,02063965 0,02746933 ! regulation of smooth muscle cell proliferation GO:0048660 30 26 0,000 0,02063965 0,02745931 ! regulation of actin filament depolymerization GO:0030834 28 26 0,000 0,02063965 0,0274493 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,02063965 0,02743929 ! iron ion transport GO:0006826 33 26 0,000 0,02063965 0,0274293 ! regulation of synaptic plasticity GO:0048167 36 26 0,000 0,02063965 0,02741931 ! glucose transport GO:0015758 27 26 0,000 0,02063965 0,02740933 ! insulin receptor signaling pathway GO:0008286 34 26 0,000 0,02063965 0,02739935 ! spinal cord development GO:0021510 30 26 0,000 0,02063965 0,02738939 ! histone deacetylase complex GO:0000118 29 26 0,000 0,02063965 0,02737943 ! response to endoplasmic reticulum stress GO:0034976 30 26 0,000 0,02063965 0,02736947 ! regulation of peptide secretion GO:0002791 30 26 0,000 0,02063965 0,02735953 ! regulation of production of molecular mediator of immune response GO:0002700 27 26 0,000 0,02063965 0,02734959 ! RNA helicase activity GO:0003724 46 26 0,000 0,02063965 0,02733966 ! brush border GO:0005903 30 26 0,000 0,02063965 0,02732974 ! gap junction GO:0005921 29 26 0,000 0,02063965 0,02731982 ! anion:cation symporter activity GO:0015296 29 26 0,000 0,02063965 0,02730991 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 39 27 0,000 0,02142548 0,02833943 ! mRNA catabolic process GO:0006402 31 27 0,000 0,02142548 0,02832916 ! myelination GO:0042552 31 27 0,000 0,02142548 0,0283189 ! trans-Golgi network GO:0005802 31 27 0,000 0,02142548 0,02830864 ! transferase activity, transferring nitrogenous groups GO:0016769 29 27 0,000 0,02142548 0,02829839 ! spliceosomal snRNP biogenesis GO:0000387 29 27 0,000 0,02142548 0,02828815 ! solute:solute antiporter activity GO:0015300 28 27 0,000 0,02142548 0,02827791 ! vasculogenesis GO:0001570 32 27 0,000 0,02142548 0,02826769 ! hexose transport GO:0008645 28 27 0,000 0,02142548 0,02825747 GO:0015749|monosaccharide transport, ! regulation of innate immune response GO:0045088 28 27 0,000 0,02142548 0,02824725 ! cellular response to oxidative stress GO:0034599 32 27 0,000 0,02142548 0,02823705 ! response to organic cyclic substance GO:0014070 34 27 0,000 0,02142548 0,02822685 ! cell fate determination GO:0001709 29 27 0,000 0,02142548 0,02821666 ! lipid oxidation GO:0034440 29 27 0,000 0,02142548 0,02820648 GO:0019395|fatty acid oxidation, ! fatty acid catabolic process GO:0009062 31 27 0,000 0,02142548 0,0281963 ! collagen binding GO:0005518 29 27 0,000 0,02142548 0,02818613 ! carboxy-lyase activity GO:0016831 27 27 0,000 0,02142548 0,02817597 ! phospholipid transporter activity GO:0005548 30 27 0,000 0,02142548 0,02816582 ! liver development GO:0001889 33 27 0,000 0,02142548 0,02815567 ! mitotic sister chromatid segregation GO:0000070 46 27 0,000 0,02142548 0,02814554 ! determination of bilateral symmetry GO:0009855 32 27 0,000 0,02142548 0,0281354 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! integrin complex GO:0008305 30 27 0,000 0,02142548 0,02812528 ! membrane docking GO:0022406 29 27 0,000 0,02142548 0,02811516 ! detection of light stimulus involved in sensory perception GO:0050962 29 27 0,000 0,02142548 0,02810505 GO:0050908|detection of light stimulus involved in visual perception, ! fat cell differentiation GO:0045444 30 27 0,000 0,02142548 0,02809495 ! multicellular organismal macromolecule metabolic process GO:0044259 28 27 0,000 0,02142548 0,02808486 ! respiratory gaseous exchange GO:0007585 30 27 0,000 0,02142548 0,02807477 ! phospholipid transport GO:0015914 29 27 0,000 0,02142548 0,02806469 ! sarcoplasmic reticulum GO:0016529 29 27 0,000 0,02142548 0,02805461 ! aminopeptidase activity GO:0004177 33 27 0,000 0,02142548 0,02804455 ! cellular response to nutrient levels GO:0031669 28 27 0,000 0,02142548 0,02803449 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 33 27 0,000 0,02142548 0,02802444 ! biogenic amine biosynthetic process GO:0042401 29 27 0,000 0,02142548 0,02801439 ! negative regulation of transcription regulator activity GO:0090048 32 27 0,000 0,02142548 0,02800435 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 29 27 0,000 0,02142548 0,02799432 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 31 28 0,000 0,02221073 0,02900993 ! Golgi stack GO:0005795 30 28 0,000 0,02221073 0,02899955 ! male gonad development GO:0008584 32 28 0,000 0,02221073 0,02898917 ! regulation of fatty acid metabolic process GO:0019217 41 28 0,000 0,02221073 0,0289788 ! lipoprotein binding GO:0008034 31 28 0,000 0,02221073 0,02896844 ! mesoderm formation GO:0001707 34 28 0,000 0,02221073 0,02895809 ! negative regulation of MAP kinase activity GO:0043407 30 28 0,000 0,02221073 0,02894774 ! peptidyl-tyrosine modification GO:0018212 32 28 0,000 0,02221073 0,0289374 ! deoxyribonuclease activity GO:0004536 56 28 0,000 0,02221073 0,02892707 ! nicotinamide metabolic process GO:0006769 32 28 0,000 0,02221073 0,02891675 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 31 28 0,000 0,02221073 0,02890643 ! regulation of osteoblast differentiation GO:0045667 33 28 0,000 0,02221073 0,02889612 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 30 28 0,000 0,02221073 0,02888582 ! negative regulation of neuron apoptosis GO:0043524 39 28 0,000 0,02221073 0,02887553 ! tissue homeostasis GO:0001894 31 28 0,000 0,02221073 0,02886524 GO:0048871|multicellular organismal homeostasis, ! DNA damage checkpoint GO:0000077 48 28 0,000 0,02221073 0,02885496 ! negative regulation of protein complex assembly GO:0031333 39 28 0,000 0,02221073 0,02884469 ! regulation of carbohydrate metabolic process GO:0006109 31 28 0,000 0,02221073 0,02883442 ! sister chromatid segregation GO:0000819 49 28 0,000 0,02221073 0,02882417 ! post-embryonic development GO:0009791 32 28 0,000 0,02221073 0,02881392 ! complement activation, classical pathway GO:0006958 33 28 0,000 0,02221073 0,02880367 ! detection of visible light GO:0009584 30 28 0,000 0,02221073 0,02879344 ! calcium-mediated signaling GO:0019722 30 28 0,000 0,02221073 0,02878321 ! receptor regulator activity GO:0030545 31 28 0,000 0,02221073 0,02877299 ! acetylgalactosaminyltransferase activity GO:0008376 33 28 0,000 0,02221073 0,02876277 ! symbiosis, encompassing mutualism through parasitism GO:0044403 33 28 0,000 0,02221073 0,02875257 ! response to heat GO:0009408 33 28 0,000 0,02221073 0,02874237 ! response to xenobiotic stimulus GO:0009410 31 28 0,000 0,02221073 0,02873217 ! response to hydrogen peroxide GO:0042542 32 29 0,000 0,02299539 0,02973668 ! hormone binding GO:0042562 31 29 0,000 0,02299539 0,02972614 ! establishment or maintenance of cell polarity GO:0007163 34 29 0,000 0,02299539 0,02971561 ! striated muscle cell differentiation GO:0051146 42 29 0,000 0,02299539 0,02970509 ! NADP or NADPH binding GO:0050661 33 29 0,000 0,02299539 0,02969457 ! nucleotide receptor activity, G-protein coupled GO:0001608 31 29 0,000 0,02299539 0,02968406 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 41 29 0,000 0,02299539 0,02967356 ! erythrocyte differentiation GO:0030218 35 29 0,000 0,02299539 0,02966307 ! ceramide metabolic process GO:0006672 29 29 0,000 0,02299539 0,02965259 ! replication fork GO:0005657 42 29 0,000 0,02299539 0,02964211 ! camera-type eye morphogenesis GO:0048593 36 29 0,000 0,02299539 0,02963164 ! monosaccharide biosynthetic process GO:0046364 35 29 0,000 0,02299539 0,02962117 ! negative regulation of lymphocyte activation GO:0051250 32 29 0,000 0,02299539 0,02961072 ! alkaloid metabolic process GO:0009820 33 29 0,000 0,02299539 0,02960027 ! icosanoid biosynthetic process GO:0046456 30 29 0,000 0,02299539 0,02958983 ! regulation of pH GO:0006885 30 29 0,000 0,02299539 0,0295794 ! amino sugar metabolic process GO:0006040 41 29 0,000 0,02299539 0,02956897 ! ER-nuclear signaling pathway GO:0006984 32 29 0,000 0,02299539 0,02955855 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 34 29 0,000 0,02299539 0,02954814 ! phospholipase C activity GO:0004629 43 29 0,000 0,02299539 0,02953773 ! response to mechanical stimulus GO:0009612 33 29 0,000 0,02299539 0,02952734 ! clathrin coated vesicle membrane GO:0030665 33 29 0,000 0,02299539 0,02951695 ! sodium channel activity GO:0005272 33 29 0,000 0,02299539 0,02950657 ! sarcoplasm GO:0016528 31 29 0,000 0,02299539 0,02949619 ! detection of light stimulus GO:0009583 31 29 0,000 0,02299539 0,02948582 ! spermatid development GO:0007286 30 29 0,000 0,02299539 0,02947546 ! DNA polymerase activity GO:0034061 34 29 0,000 0,02299539 0,02946511 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 31 29 0,000 0,02299539 0,02945476 ! sarcolemma GO:0042383 30 29 0,000 0,02299539 0,02944443 ! tumor necrosis factor receptor superfamily binding GO:0032813 31 29 0,000 0,02299539 0,02943409 ! galactosyltransferase activity GO:0008378 33 29 0,000 0,02299539 0,02942377 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,02299539 0,02941345 ! transforming growth factor beta receptor signaling pathway GO:0007179 34 30 0,000 0,02377946 0,0304057 ! mitochondrial nucleoid GO:0042645 44 30 0,000 0,02377946 0,03039504 GO:0009295|nucleoid, ! cholesterol transport GO:0030301 33 30 0,000 0,02377946 0,0303844 GO:0015918|sterol transport, ! histone-lysine N-methyltransferase activity GO:0018024 34 30 0,000 0,02377946 0,03037376 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! cellular carbohydrate biosynthetic process GO:0034637 30 30 0,000 0,02377946 0,03036313 ! scavenger receptor activity GO:0005044 39 30 0,000 0,02377946 0,0303525 ! spliceosome assembly GO:0000245 34 30 0,000 0,02377946 0,03034189 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 39 30 0,000 0,02377946 0,03033128 GO:0004601|peroxidase activity, ! mesoderm morphogenesis GO:0048332 37 30 0,000 0,02377946 0,03032068 ! metanephros development GO:0001656 31 30 0,000 0,02377946 0,03031008 ! glutamate receptor activity GO:0008066 35 30 0,000 0,02377946 0,0302995 ! cyclic nucleotide metabolic process GO:0009187 31 30 0,000 0,02377946 0,03028892 ! positive regulation of MAPKKK cascade GO:0043410 36 30 0,000 0,02377946 0,03027834 ! regulation of macrophage differentiation GO:0045649 37 30 0,000 0,02377946 0,03026778 ! positive regulation of myeloid cell differentiation GO:0045639 37 30 0,000 0,02377946 0,03025722 ! negative regulation of myeloid cell differentiation GO:0045638 35 30 0,000 0,02377946 0,03024667 ! cis-trans isomerase activity GO:0016859 32 30 0,000 0,02377946 0,03023613 ! myeloid leukocyte activation GO:0002274 36 30 0,000 0,02377946 0,0302256 ! negative regulation of protein transport GO:0051224 34 30 0,000 0,02377946 0,03021507 ! cortical cytoskeleton GO:0030863 33 30 0,000 0,02377946 0,03020455 ! protein-lipid complex GO:0032994 41 30 0,000 0,02377946 0,03019403 GO:0034358|plasma lipoprotein particle, ! circadian rhythm GO:0007623 37 30 0,000 0,02377946 0,03018353 ! phosphatase binding GO:0019902 34 30 0,000 0,02377946 0,03017303 ! acute-phase response GO:0006953 44 30 0,000 0,02377946 0,03016254 ! segmentation GO:0035282 37 30 0,000 0,02377946 0,03015205 ! response to toxin GO:0009636 33 30 0,000 0,02377946 0,03014158 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,02377946 0,03013111 ! antigen binding GO:0003823 33 30 0,000 0,02377946 0,03012065 ! regulation of systemic arterial blood pressure GO:0003073 33 30 0,000 0,02377946 0,03011019 ! Golgi-associated vesicle membrane GO:0030660 37 30 0,000 0,02377946 0,03009974 ! ensheathment of neurons GO:0007272 35 30 0,000 0,02377946 0,0300893 GO:0008366|axon ensheathment, ! JAK-STAT cascade GO:0007259 43 30 0,000 0,02377946 0,03007887 ! vesicle localization GO:0051648 31 30 0,000 0,02377946 0,03006844 ! negative regulation of cell adhesion GO:0007162 34 31 0,000 0,02456294 0,03104837 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,02456294 0,03103762 ! acrosomal vesicle GO:0001669 34 31 0,000 0,02456294 0,03102687 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,02456294 0,03101613 ! protein targeting to membrane GO:0006612 35 31 0,000 0,02456294 0,0310054 ! regulation of axonogenesis GO:0050770 37 31 0,000 0,02456294 0,03099468 ! regulation of T cell differentiation GO:0045580 43 31 0,000 0,02456294 0,03098396 ! formation of primary germ layer GO:0001704 37 31 0,000 0,02456294 0,03097325 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 33 31 0,000 0,02456294 0,03096255 ! endocytic vesicle GO:0030139 33 31 0,000 0,02456294 0,03095185 ! pyridine nucleotide metabolic process GO:0019362 35 31 0,000 0,02456294 0,03094116 ! spermatid differentiation GO:0048515 32 31 0,000 0,02456294 0,03093048 ! negative regulation of catabolic process GO:0009895 34 31 0,000 0,02456294 0,03091981 ! neuron fate commitment GO:0048663 44 31 0,000 0,02456294 0,03090914 ! regulation of cellular catabolic process GO:0031329 35 31 0,000 0,02456294 0,03089848 ! regulation of JAK-STAT cascade GO:0046425 37 31 0,000 0,02456294 0,03088783 ! response to calcium ion GO:0051592 34 31 0,000 0,02456294 0,03087719 ! morphogenesis of embryonic epithelium GO:0016331 36 31 0,000 0,02456294 0,03086655 ! macromolecular complex disassembly GO:0032984 37 31 0,000 0,02456294 0,03085592 ! cell junction assembly GO:0034329 36 31 0,000 0,02456294 0,0308453 ! drug binding GO:0008144 34 31 0,000 0,02456294 0,03083469 ! positive regulation of T cell proliferation GO:0042102 38 31 0,000 0,02456294 0,03082408 ! peptide transport GO:0015833 36 31 0,000 0,02456294 0,03081348 ! DNA integrity checkpoint GO:0031570 51 31 0,000 0,02456294 0,03080289 ! peripheral nervous system development GO:0007422 35 31 0,000 0,02456294 0,0307923 ! I band GO:0031674 34 31 0,000 0,02456294 0,03078173 ! BMP signaling pathway GO:0030509 33 31 0,000 0,02456294 0,03077116 ! adult locomotory behavior GO:0008344 37 31 0,000 0,02456294 0,03076059 ! gene silencing GO:0016458 33 31 0,000 0,02456294 0,03075004 ! negative regulation of adenylate cyclase activity GO:0007194 39 32 0,000 0,02534584 0,03171925 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of secretion GO:0051048 37 32 0,000 0,02534584 0,03170837 ! negative regulation of DNA metabolic process GO:0051053 38 32 0,000 0,02534584 0,0316975 ! phosphotransferase activity, phosphate group as acceptor GO:0016776 49 32 0,000 0,02534584 0,03168664 ! meiosis I GO:0007127 53 32 0,000 0,02534584 0,03167578 ! GPI anchor biosynthetic process GO:0006506 35 32 0,000 0,02534584 0,03166494 GO:0006505|GPI anchor metabolic process, ! unsaturated fatty acid biosynthetic process GO:0006636 33 32 0,000 0,02534584 0,0316541 ! sterol biosynthetic process GO:0016126 40 32 0,000 0,02534584 0,03164326 ! vesicle coat GO:0030120 39 32 0,000 0,02534584 0,03163244 ! cytokine production GO:0001816 32 32 0,000 0,02534584 0,03162162 ! regulation of calcium ion transport GO:0051924 37 32 0,000 0,02534584 0,03161081 ! proteoglycan metabolic process GO:0006029 34 32 0,000 0,02534584 0,0316 ! sphingoid metabolic process GO:0046519 33 32 0,000 0,02534584 0,03158921 ! multicellular organismal metabolic process GO:0044236 35 32 0,000 0,02534584 0,03157842 ! oxygen binding GO:0019825 33 32 0,000 0,02534584 0,03156764 ! leukocyte chemotaxis GO:0030595 32 32 0,000 0,02534584 0,03155686 GO:0060326|cell chemotaxis, ! negative regulation of leukocyte activation GO:0002695 35 32 0,000 0,02534584 0,0315461 ! hormone biosynthetic process GO:0042446 32 32 0,000 0,02534584 0,03153534 ! double-stranded RNA binding GO:0003725 35 32 0,000 0,02534584 0,03152459 ! microtubule organizing center part GO:0044450 46 32 0,000 0,02534584 0,03151384 ! platelet alpha granule lumen GO:0031093 35 33 0,000 0,02612815 0,03247546 ! DNA helicase activity GO:0003678 55 33 0,000 0,02612815 0,0324644 ! neural tube development GO:0021915 37 33 0,000 0,02612815 0,03245335 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 33 0,000 0,02612815 0,0324423 ! pigment biosynthetic process GO:0046148 35 33 0,000 0,02612815 0,03243126 ! organelle envelope lumen GO:0031970 46 33 0,000 0,02612815 0,03242023 ! regulation of cellular ketone metabolic process GO:0010565 46 33 0,000 0,02612815 0,03240921 ! negative regulation of DNA binding GO:0043392 39 33 0,000 0,02612815 0,03239819 ! NAD or NADH binding GO:0051287 36 33 0,000 0,02612815 0,03238718 ! nucleotide catabolic process GO:0009166 35 33 0,000 0,02612815 0,03237618 ! B cell differentiation GO:0030183 37 33 0,000 0,02612815 0,03236519 ! regulation of Wnt receptor signaling pathway GO:0030111 36 33 0,000 0,02612815 0,0323542 ! aerobic respiration GO:0009060 35 33 0,000 0,02612815 0,03234322 ! embryonic organ development GO:0048568 41 33 0,000 0,02612815 0,03233225 ! placenta development GO:0001890 39 33 0,000 0,02612815 0,03232129 ! tissue remodeling GO:0048771 37 33 0,000 0,02612815 0,03231033 ! flagellum GO:0019861 34 33 0,000 0,02612815 0,03229938 ! L-amino acid transmembrane transporter activity GO:0015179 37 33 0,000 0,02612815 0,03228844 ! Rho protein signal transduction GO:0007266 35 33 0,000 0,02612815 0,03227751 ! cysteine-type endopeptidase inhibitor activity GO:0004869 35 33 0,000 0,02612815 0,03226658 ! odontogenesis GO:0042476 39 34 0,000 0,02690987 0,03322071 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,02690987 0,03320948 ! lipid homeostasis GO:0055088 37 34 0,000 0,02690987 0,03319824 ! telencephalon development GO:0021537 36 34 0,000 0,02690987 0,03318702 ! clathrin coat GO:0030118 41 34 0,000 0,02690987 0,03317581 ! cell growth GO:0016049 36 34 0,000 0,02690987 0,0331646 ! protein polymerization GO:0051258 38 34 0,000 0,02690987 0,0331534 ! condensed chromosome kinetochore GO:0000777 52 34 0,000 0,02690987 0,0331422 ! learning GO:0007612 51 34 0,000 0,02690987 0,03313102 ! keratinization GO:0031424 40 34 0,000 0,02690987 0,03311984 ! ovulation cycle process GO:0022602 35 34 0,000 0,02690987 0,03310867 ! regulation of striated muscle tissue development GO:0016202 40 34 0,000 0,02690987 0,03309751 ! regulation of protein import into nucleus GO:0042306 36 34 0,000 0,02690987 0,03308635 ! erythrocyte homeostasis GO:0034101 40 34 0,000 0,02690987 0,03307521 ! amino acid binding GO:0016597 40 34 0,000 0,02690987 0,03306407 ! regulation of protein stability GO:0031647 35 34 0,000 0,02690987 0,03305293 ! specific RNA polymerase II transcription factor activity GO:0003704 41 34 0,000 0,02690987 0,03304181 ! glycogen metabolic process GO:0005977 48 34 0,000 0,02690987 0,03303069 ! pyrimidine nucleotide metabolic process GO:0006220 41 34 0,000 0,02690987 0,03301958 ! acetylglucosaminyltransferase activity GO:0008375 40 34 0,000 0,02690987 0,03300848 ! epithelial tube morphogenesis GO:0060562 38 34 0,000 0,02690987 0,03299738 ! positive regulation of transcription factor activity GO:0051091 49 35 0,000 0,02769101 0,03394382 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 53 35 0,000 0,02769101 0,03393242 ! response to estrogen stimulus GO:0043627 48 35 0,000 0,02769101 0,03392102 ! inner ear morphogenesis GO:0042472 46 35 0,000 0,02769101 0,03390964 ! MHC protein complex GO:0042611 50 35 0,000 0,02769101 0,03389826 ! alcohol biosynthetic process GO:0046165 41 35 0,000 0,02769101 0,03388688 ! vesicle lumen GO:0031983 38 35 0,000 0,02769101 0,03387552 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! female gonad development GO:0008585 37 35 0,000 0,02769101 0,03386416 ! mesenchymal cell development GO:0014031 40 35 0,000 0,02769101 0,03385282 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! neutral lipid metabolic process GO:0006638 47 35 0,000 0,02769101 0,03384147 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 37 35 0,000 0,02769101 0,03383014 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 41 35 0,000 0,02769101 0,03381882 ! regulation of proteolysis GO:0030162 37 35 0,000 0,02769101 0,0338075 ! ovulation cycle GO:0042698 37 35 0,000 0,02769101 0,03379619 ! intramolecular oxidoreductase activity GO:0016860 35 35 0,000 0,02769101 0,03378488 ! positive regulation of catabolic process GO:0009896 38 35 0,000 0,02769101 0,03377359 ! collagen GO:0005581 54 35 0,000 0,02769101 0,0337623 ! glucan metabolic process GO:0044042 49 35 0,000 0,02769101 0,03375102 GO:0006073|cellular glucan metabolic process, ! regulation of muscle development GO:0048634 42 35 0,000 0,02769101 0,03373975 ! ER to Golgi vesicle-mediated transport GO:0006888 43 35 0,000 0,02769101 0,03372848 ! histone methyltransferase activity GO:0042054 40 35 0,000 0,02769101 0,03371722 ! cation:sugar symporter activity GO:0005402 37 35 0,000 0,02769101 0,03370597 GO:0005351|sugar:hydrogen symporter activity, ! carbohydrate homeostasis GO:0033500 49 35 0,000 0,02769101 0,03369473 GO:0042593|glucose homeostasis, ! cytosolic small ribosomal subunit GO:0022627 36 35 0,000 0,02769101 0,0336835 ! maintenance of protein location GO:0045185 45 35 0,000 0,02769101 0,03367227 ! polyol metabolic process GO:0019751 46 35 0,000 0,02769101 0,03366105 ! cytokinesis GO:0000910 38 35 0,000 0,02769101 0,03364983 ! O-acyltransferase activity GO:0008374 36 35 0,000 0,02769101 0,03363863 ! purinergic nucleotide receptor activity GO:0001614 40 36 0,000 0,02847156 0,03457532 GO:0016502|nucleotide receptor activity, ! mitochondrial respiratory chain complex I GO:0005747 37 36 0,000 0,02847156 0,03456381 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 42 36 0,000 0,02847156 0,03455232 ! positive regulation of neurogenesis GO:0050769 38 36 0,000 0,02847156 0,03454082 ! SMAD binding GO:0046332 39 36 0,000 0,02847156 0,03452934 ! negative regulation of cell activation GO:0050866 40 36 0,000 0,02847156 0,03451787 ! inositol or phosphatidylinositol kinase activity GO:0004428 51 36 0,000 0,02847156 0,0345064 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 36 0,000 0,02847156 0,03449494 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 38 36 0,000 0,02847156 0,03448349 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 36 0,000 0,02847156 0,03447204 ! hormone-mediated signaling GO:0009755 41 36 0,000 0,02847156 0,0344606 ! nucleus organization GO:0006997 42 36 0,000 0,02847156 0,03444917 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 44 36 0,000 0,02847156 0,03443775 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 42 36 0,000 0,02847156 0,03442634 ! carboxypeptidase activity GO:0004180 37 36 0,000 0,02847156 0,03441493 ! energy coupled proton transport, down electrochemical gradient GO:0015985 37 36 0,000 0,02847156 0,03440353 GO:0015986|ATP synthesis coupled proton transport, ! female gamete generation GO:0007292 39 36 0,000 0,02847156 0,03439214 ! maintenance of location in cell GO:0051651 38 36 0,000 0,02847156 0,03438075 ! activation of adenylate cyclase activity GO:0007190 44 37 0,000 0,02925153 0,03531091 ! regulation of hormone secretion GO:0046883 43 37 0,000 0,02925153 0,03529923 ! sugar transmembrane transporter activity GO:0051119 39 37 0,000 0,02925153 0,03528756 GO:0015144|carbohydrate transmembrane transporter activity, ! regulation of Rab protein signal transduction GO:0032483 40 37 0,000 0,02925153 0,0352759 GO:0032313|regulation of Rab GTPase activity, ! regulation of action potential in neuron GO:0019228 44 37 0,000 0,02925153 0,03526424 ! glycerol ether metabolic process GO:0006662 49 37 0,000 0,02925153 0,03525259 ! endoribonuclease activity GO:0004521 48 37 0,000 0,02925153 0,03524095 ! hindbrain development GO:0030902 43 37 0,000 0,02925153 0,03522931 ! isoprenoid metabolic process GO:0006720 41 37 0,000 0,02925153 0,03521768 ! pigmentation GO:0043473 51 37 0,000 0,02925153 0,03520607 ! regulation of neuron projection development GO:0010975 43 37 0,000 0,02925153 0,03519445 ! condensed chromosome, centromeric region GO:0000779 55 37 0,000 0,02925153 0,03518285 ! metalloexopeptidase activity GO:0008235 39 37 0,000 0,02925153 0,03517125 ! monocarboxylic acid transport GO:0015718 43 37 0,000 0,02925153 0,03515967 ! sensory perception of taste GO:0050909 37 37 0,000 0,02925153 0,03514808 ! cell junction organization GO:0034330 44 37 0,000 0,02925153 0,03513651 ! skeletal muscle fiber development GO:0048741 41 37 0,000 0,02925153 0,03512495 ! development of primary female sexual characteristics GO:0046545 40 37 0,000 0,02925153 0,03511339 GO:0046660|female sex differentiation, ! NADH dehydrogenase (ubiquinone) activity GO:0008137 38 37 0,000 0,02925153 0,03510184 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! ion transmembrane transport GO:0034220 38 37 0,000 0,02925153 0,03509029 ! regulation of lymphocyte mediated immunity GO:0002706 43 37 0,000 0,02925153 0,03507876 ! coated pit GO:0005905 44 37 0,000 0,02925153 0,03506723 ! positive regulation of adenylate cyclase activity GO:0045762 45 38 0,000 0,03003091 0,03598974 ! regulation of translational initiation GO:0006446 50 38 0,000 0,03003091 0,03597792 ! negative regulation of binding GO:0051100 44 38 0,000 0,03003091 0,03596611 ! organic ether metabolic process GO:0018904 50 38 0,000 0,03003091 0,03595431 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 43 38 0,000 0,03003091 0,03594251 ! regulation of lymphocyte differentiation GO:0045619 51 38 0,000 0,03003091 0,03593072 ! carbon-carbon lyase activity GO:0016830 41 38 0,000 0,03003091 0,03591894 ! hydro-lyase activity GO:0016836 44 38 0,000 0,03003091 0,03590717 ! synapse organization GO:0050808 43 38 0,000 0,03003091 0,03589541 ! viral infectious cycle GO:0019058 40 38 0,000 0,03003091 0,03588365 ! phosphoinositide biosynthetic process GO:0046489 41 38 0,000 0,03003091 0,0358719 ! negative regulation of protein complex disassembly GO:0043242 42 38 0,000 0,03003091 0,03586016 ! organic anion transport GO:0015711 42 38 0,000 0,03003091 0,03584842 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 52 38 0,000 0,03003091 0,0358367 ! monosaccharide binding GO:0048029 41 38 0,000 0,03003091 0,03582498 ! muscle fiber development GO:0048747 42 38 0,000 0,03003091 0,03581326 ! development of primary male sexual characteristics GO:0046546 46 38 0,000 0,03003091 0,03580156 ! phagocytosis GO:0006909 44 38 0,000 0,03003091 0,03578986 ! general RNA polymerase II transcription factor activity GO:0016251 43 38 0,000 0,03003091 0,03577818 ! DNA-directed RNA polymerase activity GO:0003899 49 38 0,000 0,03003091 0,0357665 GO:0034062|RNA polymerase activity, ! extrinsic to plasma membrane GO:0019897 43 38 0,000 0,03003091 0,03575482 ! cytosolic large ribosomal subunit GO:0022625 43 38 0,000 0,03003091 0,03574316 ! Rab GTPase activator activity GO:0005097 41 38 0,000 0,03003091 0,0357315 ! cellular response to insulin stimulus GO:0032869 47 38 0,000 0,03003091 0,03571985 ! monocarboxylic acid binding GO:0033293 44 39 0,000 0,03080971 0,03663424 ! induction of apoptosis by extracellular signals GO:0008624 44 39 0,000 0,03080971 0,0366223 ! heterocycle biosynthetic process GO:0018130 51 39 0,000 0,03080971 0,03661037 ! positive regulation of DNA binding GO:0043388 53 39 0,000 0,03080971 0,03659845 ! T cell differentiation GO:0030217 64 39 0,000 0,03080971 0,03658654 ! DNA-dependent ATPase activity GO:0008094 63 39 0,000 0,03080971 0,03657463 ! cell fate specification GO:0001708 55 39 0,000 0,03080971 0,03656273 ! positive regulation of cyclase activity GO:0031281 46 39 0,000 0,03080971 0,03655084 ! regulation of adaptive immune response GO:0002819 44 39 0,000 0,03080971 0,03653896 ! regulation of cell morphogenesis involved in differentiation GO:0010769 45 39 0,000 0,03080971 0,03652708 ! receptor-mediated endocytosis GO:0006898 44 39 0,000 0,03080971 0,03651522 ! regulation of metal ion transport GO:0010959 45 39 0,000 0,03080971 0,03650336 ! energy reserve metabolic process GO:0006112 53 39 0,000 0,03080971 0,03649151 ! amine receptor activity GO:0008227 48 39 0,000 0,03080971 0,03647966 ! cytoskeleton-dependent intracellular transport GO:0030705 42 39 0,000 0,03080971 0,03646783 ! embryonic skeletal system morphogenesis GO:0048704 46 39 0,000 0,03080971 0,036456 ! neuropeptide receptor activity GO:0008188 41 39 0,000 0,03080971 0,03644418 ! double-strand break repair GO:0006302 70 39 0,000 0,03080971 0,03643236 ! pigment metabolic process GO:0042440 43 39 0,000 0,03080971 0,03642056 ! RNA modification GO:0009451 39 39 0,000 0,03080971 0,03640876 ! damaged DNA binding GO:0003684 51 40 0,000 0,03158793 0,03731631 ! regulation of intracellular protein transport GO:0033157 43 40 0,000 0,03158793 0,03730423 ! peroxisomal membrane GO:0005778 44 40 0,000 0,03158793 0,03729216 GO:0031903|microbody membrane, ! actin filament binding GO:0051015 41 40 0,000 0,03158793 0,03728009 ! positive regulation of cell development GO:0010720 43 40 0,000 0,03158793 0,03726804 ! ribonucleoside metabolic process GO:0009119 47 40 0,000 0,03158793 0,03725599 ! biopolymer methylation GO:0043414 45 40 0,000 0,03158793 0,03724395 ! neuron migration GO:0001764 43 40 0,000 0,03158793 0,03723191 ! regulation of protein secretion GO:0050708 45 40 0,000 0,03158793 0,03721989 ! oxidoreduction coenzyme metabolic process GO:0006733 45 40 0,000 0,03158793 0,03720787 ! dorsal/ventral pattern formation GO:0009953 42 40 0,000 0,03158793 0,03719586 ! regulation of actin filament polymerization GO:0030833 53 40 0,000 0,03158793 0,03718386 ! positive regulation of defense response GO:0031349 41 40 0,000 0,03158793 0,03717186 ! mammary gland development GO:0030879 47 40 0,000 0,03158793 0,03715987 ! neuropeptide binding GO:0042923 42 40 0,000 0,03158793 0,03714789 ! regulation of tube size GO:0035150 44 40 0,000 0,03158793 0,03713592 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 42 40 0,000 0,03158793 0,03712396 ! positive regulation of gene-specific transcription GO:0043193 46 40 0,000 0,03158793 0,037112 ! regulation of leukocyte mediated immunity GO:0002703 46 40 0,000 0,03158793 0,03710005 ! inorganic anion transmembrane transporter activity GO:0015103 43 40 0,000 0,03158793 0,03708811 ! chromatin remodeling GO:0006338 44 40 0,000 0,03158793 0,03707618 ! solute:hydrogen symporter activity GO:0015295 44 40 0,000 0,03158793 0,03706426 ! protein amino acid N-linked glycosylation GO:0006487 46 41 0,000 0,03236556 0,03796449 ! Notch signaling pathway GO:0007219 46 41 0,000 0,03236556 0,03795229 ! keratin filament GO:0045095 44 41 0,000 0,03236556 0,03794009 ! peptide metabolic process GO:0006518 42 41 0,000 0,03236556 0,03792791 ! polysaccharide biosynthetic process GO:0000271 42 41 0,000 0,03236556 0,03791573 ! late endosome membrane GO:0031902 45 41 0,000 0,03236556 0,03790356 ! icosanoid metabolic process GO:0006690 51 41 0,000 0,03236556 0,03789139 ! positive regulation of lyase activity GO:0051349 48 41 0,000 0,03236556 0,03787923 ! integral to endoplasmic reticulum membrane GO:0030176 43 41 0,000 0,03236556 0,03786709 ! glycolysis GO:0006096 43 41 0,000 0,03236556 0,03785495 ! branching morphogenesis of a tube GO:0048754 54 41 0,000 0,03236556 0,03784281 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 51 41 0,000 0,03236556 0,03783069 ! proton-transporting two-sector ATPase complex GO:0016469 42 41 0,000 0,03236556 0,03781857 ! response to reactive oxygen species GO:0000302 49 42 0,000 0,03314261 0,03871414 ! cellular amide metabolic process GO:0043603 56 42 0,000 0,03314261 0,03870175 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 43 42 0,000 0,03314261 0,03868936 ! ER-Golgi intermediate compartment GO:0005793 52 42 0,000 0,03314261 0,03867698 ! regulation of multicellular organism growth GO:0040014 46 42 0,000 0,03314261 0,03866462 ! integral to Golgi membrane GO:0030173 55 42 0,000 0,03314261 0,03865225 ! developmental growth GO:0048589 45 42 0,000 0,03314261 0,0386399 ! structural constituent of muscle GO:0008307 46 42 0,000 0,03314261 0,03862756 ! mitochondrial transport GO:0006839 45 42 0,000 0,03314261 0,03861522 ! protein methyltransferase activity GO:0008276 49 42 0,000 0,03314261 0,03860289 ! metal cluster binding GO:0051540 47 42 0,000 0,03314261 0,03859057 GO:0051536|iron-sulfur cluster binding, ! feeding behavior GO:0007631 48 42 0,000 0,03314261 0,03857826 ! protein serine/threonine phosphatase activity GO:0004722 45 42 0,000 0,03314261 0,03856595 ! ribonucleoprotein complex assembly GO:0022618 47 42 0,000 0,03314261 0,03855365 ! positive regulation of cell cycle GO:0045787 56 43 0,000 0,03391908 0,03944431 ! RNA catabolic process GO:0006401 49 43 0,000 0,03391908 0,03943174 ! ear morphogenesis GO:0042471 56 43 0,000 0,03391908 0,03941918 ! cellular amino acid biosynthetic process GO:0008652 49 43 0,000 0,03391908 0,03940663 ! regulation of epithelial cell proliferation GO:0050678 50 43 0,000 0,03391908 0,03939408 ! cell recognition GO:0008037 51 43 0,000 0,03391908 0,03938154 ! positive regulation of cytokine production GO:0001819 46 43 0,000 0,03391908 0,03936901 ! epithelial cell differentiation GO:0030855 56 43 0,000 0,03391908 0,03935649 ! gliogenesis GO:0042063 46 43 0,000 0,03391908 0,03934398 ! endosome transport GO:0016197 48 43 0,000 0,03391908 0,03933147 ! striated muscle contraction GO:0006941 45 43 0,000 0,03391908 0,03931897 ! positive regulation of cytokine biosynthetic process GO:0042108 48 43 0,000 0,03391908 0,03930648 ! antioxidant activity GO:0016209 53 43 0,000 0,03391908 0,039294 ! sulfur compound biosynthetic process GO:0044272 47 43 0,000 0,03391908 0,03928153 ! activation of caspase activity GO:0006919 60 43 0,000 0,03391908 0,03926906 ! vascular process in circulatory system GO:0003018 48 43 0,000 0,03391908 0,0392566 ! histone modification GO:0016570 45 43 0,000 0,03391908 0,03924415 ! cellular amino acid derivative biosynthetic process GO:0042398 55 43 0,000 0,03391908 0,03923171 ! regulation of nucleocytoplasmic transport GO:0046822 46 44 0,000 0,03469497 0,0401164 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 50 44 0,000 0,03469497 0,04010369 ! negative regulation of cell migration GO:0030336 53 44 0,000 0,03469497 0,04009098 ! ATP synthesis coupled electron transport GO:0042773 45 44 0,000 0,03469497 0,04007829 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! nucleoside monophosphate biosynthetic process GO:0009124 50 44 0,000 0,03469497 0,0400656 ! chemokine activity GO:0008009 48 44 0,000 0,03469497 0,04005292 ! ruffle GO:0001726 50 44 0,000 0,03469497 0,04004025 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 51 44 0,000 0,03469497 0,04002759 ! regulation of neuron apoptosis GO:0043523 58 44 0,000 0,03469497 0,04001493 ! cartilage development GO:0051216 48 44 0,000 0,03469497 0,04000229 ! membrane fusion GO:0006944 52 44 0,000 0,03469497 0,03998965 ! channel regulator activity GO:0016247 54 44 0,000 0,03469497 0,03997702 ! excretion GO:0007588 53 44 0,000 0,03469497 0,03996439 ! male sex differentiation GO:0046661 52 44 0,000 0,03469497 0,03995178 ! RNA elongation from RNA polymerase II promoter GO:0006368 49 44 0,000 0,03469497 0,03993917 ! amino acid activation GO:0043038 45 44 0,000 0,03469497 0,03992657 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! microbody part GO:0044438 48 44 0,000 0,03469497 0,03991398 GO:0044439|peroxisomal part, ! positive regulation of binding GO:0051099 59 45 0,000 0,03547027 0,04079305 ! solute:sodium symporter activity GO:0015370 51 45 0,000 0,03547027 0,04078019 ! transferase activity, transferring pentosyl groups GO:0016763 50 45 0,000 0,03547027 0,04076734 ! organellar ribosome GO:0000313 46 45 0,000 0,03547027 0,0407545 GO:0005761|mitochondrial ribosome, ! platelet alpha granule GO:0031091 49 45 0,000 0,03547027 0,04074167 ! single-stranded DNA binding GO:0003697 48 45 0,000 0,03547027 0,04072885 ! intrinsic to Golgi membrane GO:0031228 60 45 0,000 0,03547027 0,04071603 ! transport vesicle GO:0030133 53 45 0,000 0,03547027 0,04070322 ! regulation of endocytosis GO:0030100 52 45 0,000 0,03547027 0,04069042 ! ligase activity, forming carbon-oxygen bonds GO:0016875 47 45 0,000 0,03547027 0,04067763 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! regulation of protein complex disassembly GO:0043244 49 45 0,000 0,03547027 0,04066485 ! nuclear matrix GO:0016363 56 45 0,000 0,03547027 0,04065207 ! unsaturated fatty acid metabolic process GO:0033559 55 45 0,000 0,03547027 0,0406393 ! regulation of T cell proliferation GO:0042129 53 45 0,000 0,03547027 0,04062654 ! regulation of myeloid leukocyte differentiation GO:0002761 54 45 0,000 0,03547027 0,04061379 ! DNA-dependent DNA replication GO:0006261 66 45 0,000 0,03547027 0,04060105 ! coated vesicle membrane GO:0030662 52 45 0,000 0,03547027 0,04058831 ! covalent chromatin modification GO:0016569 47 45 0,000 0,03547027 0,04057559 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 51 45 0,000 0,03547027 0,04056287 ! synaptosome GO:0019717 50 45 0,000 0,03547027 0,04055016 ! chemokine receptor binding GO:0042379 50 45 0,000 0,03547027 0,04053745 ! regulation of action potential GO:0001508 56 46 0,000 0,03624499 0,04140988 ! immunoglobulin mediated immune response GO:0016064 51 46 0,000 0,03624499 0,04139691 ! regulation of inflammatory response GO:0050727 49 46 0,000 0,03624499 0,04138395 ! eye morphogenesis GO:0048592 57 46 0,000 0,03624499 0,04137101 ! regulation of JNK cascade GO:0046328 53 46 0,000 0,03624499 0,04135807 ! methylation GO:0032259 51 46 0,000 0,03624499 0,04134513 ! positive regulation of protein transport GO:0051222 50 46 0,000 0,03624499 0,04133221 ! regulation of ion transport GO:0043269 54 46 0,000 0,03624499 0,04131929 ! leukocyte migration GO:0050900 49 46 0,000 0,03624499 0,04130638 ! neuromuscular process GO:0050905 56 46 0,000 0,03624499 0,04129348 ! sulfotransferase activity GO:0008146 54 46 0,000 0,03624499 0,04128059 ! JNK cascade GO:0007254 48 46 0,000 0,03624499 0,04126771 ! SH3/SH2 adaptor activity GO:0005070 52 46 0,000 0,03624499 0,04125483 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 54 47 0,000 0,03701913 0,04212283 ! auxiliary transport protein activity GO:0015457 58 47 0,000 0,03701913 0,0421097 ! regulation of actin polymerization or depolymerization GO:0008064 60 47 0,000 0,03701913 0,04209657 ! microtubule binding GO:0008017 61 47 0,000 0,03701913 0,04208345 ! morphogenesis of a branching structure GO:0001763 70 47 0,000 0,03701913 0,04207034 ! carbon-oxygen lyase activity GO:0016835 53 47 0,000 0,03701913 0,04205724 ! regulation of protein polymerization GO:0032271 60 47 0,000 0,03701913 0,04204415 ! viral reproductive process GO:0022415 53 47 0,000 0,03701913 0,04203106 ! RNA elongation GO:0006354 52 47 0,000 0,03701913 0,04201798 ! negative regulation of immune system process GO:0002683 58 47 0,000 0,03701913 0,04200492 ! mRNA binding GO:0003729 65 47 0,000 0,03701913 0,04199185 ! axon GO:0030424 53 48 0,000 0,0377927 0,042856 ! protein amino acid lipidation GO:0006497 53 48 0,000 0,0377927 0,04284268 ! stress-activated protein kinase signaling pathway GO:0031098 50 48 0,000 0,0377927 0,04282937 ! proteasome complex GO:0000502 50 48 0,000 0,0377927 0,04281607 ! glutamine family amino acid metabolic process GO:0009064 62 48 0,000 0,0377927 0,04280278 ! protein homooligomerization GO:0051260 63 48 0,000 0,0377927 0,0427895 ! regulation of cell projection organization GO:0031344 54 48 0,000 0,0377927 0,04277622 ! kinetochore GO:0000776 69 48 0,000 0,0377927 0,04276295 ! positive regulation of caspase activity GO:0043280 65 48 0,000 0,0377927 0,04274969 GO:0010952|positive regulation of peptidase activity, ! detection of stimulus involved in sensory perception GO:0050906 53 48 0,000 0,0377927 0,04273644 ! growth factor receptor binding GO:0070851 58 48 0,000 0,0377927 0,0427232 ! N-methyltransferase activity GO:0008170 53 48 0,000 0,0377927 0,04270996 ! inner ear development GO:0048839 60 48 0,000 0,0377927 0,04269673 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 57 48 0,000 0,0377927 0,04268352 ! amino acid transmembrane transporter activity GO:0015171 53 48 0,000 0,0377927 0,04267031 ! chromatin remodeling complex GO:0016585 54 48 0,000 0,0377927 0,0426571 ! B cell mediated immunity GO:0019724 53 48 0,000 0,0377927 0,04264391 ! steroid hormone receptor activity GO:0003707 61 48 0,000 0,0377927 0,04263072 ! regulation of cell shape GO:0008360 55 48 0,000 0,0377927 0,04261754 ! establishment of organelle localization GO:0051656 58 48 0,000 0,0377927 0,04260437 ! cell cortex part GO:0044448 54 48 0,000 0,0377927 0,04259121 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 52 49 0,000 0,03856568 0,04344892 ! regulation of neurotransmitter levels GO:0001505 55 49 0,000 0,03856568 0,0434355 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 54 49 0,000 0,03856568 0,0434221 ! response to temperature stimulus GO:0009266 57 49 0,000 0,03856568 0,0434087 ! Golgi-associated vesicle GO:0005798 59 49 0,000 0,03856568 0,04339531 ! lipid modification GO:0030258 55 49 0,000 0,03856568 0,04338193 ! synaptic vesicle GO:0008021 56 49 0,000 0,03856568 0,04336855 ! regulation of gene expression, epigenetic GO:0040029 64 49 0,000 0,03856568 0,04335519 ! pyridoxal phosphate binding GO:0030170 63 49 0,000 0,03856568 0,04334183 GO:0070279|vitamin B6 binding, ! exonuclease activity GO:0004527 79 49 0,000 0,03856568 0,04332849 ! maintenance of location GO:0051235 62 49 0,000 0,03856568 0,04331515 ! negative regulation of cell motion GO:0051271 60 49 0,000 0,03856568 0,04330181 ! regulation of actin filament length GO:0030832 62 49 0,000 0,03856568 0,04328849 ! nuclear periphery GO:0034399 60 49 0,000 0,03856568 0,04327517 ! regulation of muscle contraction GO:0006937 57 49 0,000 0,03856568 0,04326187 ! negative regulation of cytoskeleton organization GO:0051494 73 49 0,000 0,03856568 0,04324857 ! nucleotide-excision repair GO:0006289 53 49 0,000 0,03856568 0,04323528 ! respiratory electron transport chain GO:0022904 51 50 0,000 0,03933808 0,04408765 ! cytokine-mediated signaling pathway GO:0019221 56 50 0,000 0,03933808 0,04407411 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,03933808 0,04406058 ! embryonic skeletal system development GO:0048706 59 50 0,000 0,03933808 0,04404706 ! glucose catabolic process GO:0006007 54 50 0,000 0,03933808 0,04403354 ! aging GO:0007568 92 50 0,000 0,03933808 0,04402003 ! generation of a signal involved in cell-cell signaling GO:0003001 59 50 0,000 0,03933808 0,04400654 ! heart morphogenesis GO:0003007 57 50 0,000 0,03933808 0,04399305 ! integrin binding GO:0005178 56 50 0,000 0,03933808 0,04397956 ! detection of abiotic stimulus GO:0009582 56 50 0,000 0,03933808 0,04396609 ! regulation of angiogenesis GO:0045765 56 51 0,000 0,0401099 0,04481498 ! positive regulation of cell migration GO:0030335 63 51 0,000 0,0401099 0,04480126 ! regulation of ossification GO:0030278 59 51 0,000 0,0401099 0,04478755 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 60 51 0,000 0,0401099 0,04477384 ! cellular polysaccharide metabolic process GO:0044264 65 51 0,000 0,0401099 0,04476015 ! endocrine system development GO:0035270 55 51 0,000 0,0401099 0,04474646 ! germ cell development GO:0007281 56 51 0,000 0,0401099 0,04473278 ! transferase activity, transferring sulfur-containing groups GO:0016782 60 52 0,000 0,04088115 0,04557898 ! regulation of cellular component size GO:0032535 66 52 0,000 0,04088115 0,04556505 ! carbohydrate transport GO:0008643 57 52 0,000 0,04088115 0,04555114 ! ubiquitin thiolesterase activity GO:0004221 64 52 0,000 0,04088115 0,04553723 ! nucleoside monophosphate metabolic process GO:0009123 58 52 0,000 0,04088115 0,04552333 ! cell maturation GO:0048469 68 52 0,000 0,04088115 0,04550944 ! regulation of intracellular transport GO:0032386 57 52 0,000 0,04088115 0,04549555 ! vesicle organization GO:0016050 59 52 0,000 0,04088115 0,04548168 ! kidney development GO:0001822 55 52 0,000 0,04088115 0,04546781 ! cellular component disassembly GO:0022411 69 52 0,000 0,04088115 0,04545395 ! cell redox homeostasis GO:0045454 57 52 0,000 0,04088115 0,0454401 ! lipoprotein biosynthetic process GO:0042158 57 52 0,000 0,04088115 0,04542626 ! lipid transporter activity GO:0005319 58 52 0,000 0,04088115 0,04541243 ! cytokine receptor activity GO:0004896 54 52 0,000 0,04088115 0,04539861 ! antiporter activity GO:0015297 53 52 0,000 0,04088115 0,04538479 ! embryonic limb morphogenesis GO:0030326 62 53 0,000 0,04165181 0,04622629 GO:0035113|embryonic appendage morphogenesis, ! glycosaminoglycan metabolic process GO:0030203 60 53 0,000 0,04165181 0,04621223 ! N-acetyltransferase activity GO:0008080 59 53 0,000 0,04165181 0,04619818 ! basement membrane GO:0005604 55 53 0,000 0,04165181 0,04618414 ! water-soluble vitamin metabolic process GO:0006767 59 53 0,000 0,04165181 0,0461701 ! negative regulation of response to stimulus GO:0048585 68 53 0,000 0,04165181 0,04615608 ! viral reproduction GO:0016032 59 53 0,000 0,04165181 0,04614206 ! chloride transport GO:0006821 60 53 0,000 0,04165181 0,04612805 ! oxygen and reactive oxygen species metabolic process GO:0006800 58 53 0,000 0,04165181 0,04611405 ! regulation of protein catabolic process GO:0042176 56 53 0,000 0,04165181 0,04610006 ! regulation of DNA replication GO:0006275 75 53 0,000 0,04165181 0,04608608 ! DNA catabolic process GO:0006308 57 53 0,000 0,04165181 0,04607211 ! heterocycle catabolic process GO:0046700 56 53 0,000 0,04165181 0,04605814 ! integrin-mediated signaling pathway GO:0007229 59 53 0,000 0,04165181 0,04604418 ! single fertilization GO:0007338 58 53 0,000 0,04165181 0,04603024 ! activation of phospholipase C activity GO:0007202 61 54 0,000 0,0424219 0,04686708 GO:0010863|positive regulation of phospholipase C activity, ! double-stranded DNA binding GO:0003690 63 54 0,000 0,0424219 0,04685289 ! mitochondrial respiratory chain GO:0005746 55 54 0,000 0,0424219 0,04683871 ! nucleoside metabolic process GO:0009116 62 54 0,000 0,0424219 0,04682453 ! coated membrane GO:0048475 65 54 0,000 0,0424219 0,04681037 GO:0030117|membrane coat, ! nucleosome GO:0000786 59 54 0,000 0,0424219 0,04679622 ! regulation of protein complex assembly GO:0043254 67 54 0,000 0,0424219 0,04678207 ! cellular defense response GO:0006968 61 54 0,000 0,0424219 0,04676793 ! gastrulation GO:0007369 62 54 0,000 0,0424219 0,0467538 ! dendrite GO:0030425 60 55 0,000 0,04319141 0,04758751 ! positive regulation of phospholipase activity GO:0010518 62 55 0,000 0,04319141 0,04757315 ! respiratory chain GO:0070469 57 55 0,000 0,04319141 0,04755879 ! coenzyme biosynthetic process GO:0009108 68 55 0,000 0,04319141 0,04754444 ! extracellular matrix organization GO:0030198 77 55 0,000 0,04319141 0,04753009 ! positive regulation of cell motion GO:0051272 69 55 0,000 0,04319141 0,04751576 ! protein amino acid autophosphorylation GO:0046777 61 55 0,000 0,04319141 0,04750143 ! translation initiation factor activity GO:0003743 66 55 0,000 0,04319141 0,04748712 ! regulation of bone remodeling GO:0046850 64 56 0,000 0,04396034 0,04831796 ! heat shock protein binding GO:0031072 62 56 0,000 0,04396034 0,04830341 ! late endosome GO:0005770 60 56 0,000 0,04396034 0,04828887 ! regulation of phospholipase activity GO:0010517 63 56 0,000 0,04396034 0,04827433 ! sphingolipid metabolic process GO:0006665 60 56 0,000 0,04396034 0,0482598 ! intrinsic to endoplasmic reticulum membrane GO:0031227 61 56 0,000 0,04396034 0,04824528 ! ribonuclease activity GO:0004540 67 56 0,000 0,04396034 0,04823077 ! positive regulation of T cell activation GO:0050870 74 56 0,000 0,04396034 0,04821627 ! mesoderm development GO:0007498 67 56 0,000 0,04396034 0,04820178 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 61 56 0,000 0,04396034 0,0481873 ! antigen processing and presentation GO:0019882 73 56 0,000 0,04396034 0,04817282 ! proton transport GO:0015992 59 56 0,000 0,04396034 0,04815836 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 57 0,000 0,0447287 0,04898538 ! chromosome segregation GO:0007059 92 57 0,000 0,0447287 0,04897067 ! glycerophospholipid biosynthetic process GO:0046474 71 57 0,000 0,0447287 0,04895598 ! diacylglycerol binding GO:0019992 65 57 0,000 0,0447287 0,0489413 ! B cell activation GO:0042113 63 57 0,000 0,0447287 0,04892662 ! small ribosomal subunit GO:0015935 58 57 0,000 0,0447287 0,04891196 ! detection of external stimulus GO:0009581 64 57 0,000 0,0447287 0,0488973 ! occluding junction GO:0070160 75 58 0,000 0,04549648 0,04972173 GO:0005923|tight junction, ! hydrogen transport GO:0006818 61 58 0,000 0,04549648 0,04970684 ! receptor signaling protein serine/threonine kinase activity GO:0004702 64 58 0,000 0,04549648 0,04969196 ! lymphocyte mediated immunity GO:0002449 65 58 0,000 0,04549648 0,04967709 ! response to nutrient GO:0007584 68 58 0,000 0,04549648 0,04966222 ! large ribosomal subunit GO:0015934 64 58 0,000 0,04549648 0,04964737 ! regulation of tissue remodeling GO:0034103 66 58 0,000 0,04549648 0,04963252 ! ligand-dependent nuclear receptor activity GO:0004879 72 58 0,000 0,04549648 0,04961768 ! myosin complex GO:0016459 64 58 0,000 0,04549648 0,04960285 ! regulation of gene-specific transcription GO:0032583 69 59 0,000 0,04626368 0,05042423 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 62 59 0,000 0,04626368 0,05040917 GO:0051213|dioxygenase activity, ! muscle cell differentiation GO:0042692 77 59 0,000 0,04626368 0,05039412 ! actin filament organization GO:0007015 65 59 0,000 0,04626368 0,05037908 ! regulation of heart contraction GO:0008016 71 59 0,000 0,04626368 0,05036404 ! hexose catabolic process GO:0019320 64 59 0,000 0,04626368 0,05034902 ! cellular amino acid catabolic process GO:0009063 63 59 0,000 0,04626368 0,050334 ! response to steroid hormone stimulus GO:0048545 74 59 0,000 0,04626368 0,05031899 ! cell projection assembly GO:0030031 79 59 0,000 0,04626368 0,050304 ! regulation of cellular response to stress GO:0080135 79 59 0,000 0,04626368 0,05028901 ! appendage morphogenesis GO:0035107 68 59 0,000 0,04626368 0,05027403 GO:0035108|limb morphogenesis, ! homeostasis of number of cells GO:0048872 67 59 0,000 0,04626368 0,05025905 ! fertilization GO:0009566 65 59 0,000 0,04626368 0,05024409 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 62 59 0,000 0,04626368 0,05022914 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 69 59 0,000 0,04626368 0,05021419 ! adult behavior GO:0030534 72 59 0,000 0,04626368 0,05019926 ! organelle localization GO:0051640 70 59 0,000 0,04626368 0,05018433 ! positive regulation of secretion GO:0051047 66 60 0,000 0,04703031 0,05100076 ! molecular adaptor activity GO:0060090 73 60 0,000 0,04703031 0,05098561 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 63 60 0,000 0,04703031 0,05097046 ! phosphoinositide metabolic process GO:0030384 68 60 0,000 0,04703031 0,05095532 ! copper ion binding GO:0005507 85 60 0,000 0,04703031 0,05094019 ! positive regulation of lipase activity GO:0060193 68 60 0,000 0,04703031 0,05092507 ! activation of immune response GO:0002253 72 60 0,000 0,04703031 0,05090996 ! cell cycle checkpoint GO:0000075 91 60 0,000 0,04703031 0,05089486 ! response to metal ion GO:0010038 65 60 0,000 0,04703031 0,05087976 ! appendage development GO:0048736 69 60 0,000 0,04703031 0,05086468 GO:0060173|limb development, ! regulation of vesicle-mediated transport GO:0060627 69 60 0,000 0,04703031 0,0508496 ! secondary metabolic process GO:0019748 67 60 0,000 0,04703031 0,05083454 ! cellular hormone metabolic process GO:0034754 64 61 0,000 0,04779636 0,05164725 ! ear development GO:0043583 76 61 0,000 0,04779636 0,05163196 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 68 61 0,000 0,04779636 0,05161667 ! learning or memory GO:0007611 79 61 0,000 0,04779636 0,0516014 ! camera-type eye development GO:0043010 69 61 0,000 0,04779636 0,05158613 ! transcription initiation from RNA polymerase II promoter GO:0006367 69 61 0,000 0,04779636 0,05157087 ! regulation of transcription factor activity GO:0051090 80 62 0,000 0,04856184 0,05238131 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 90 62 0,000 0,04856184 0,05236583 ! lysosomal membrane GO:0005765 69 62 0,000 0,04856184 0,05235035 ! membrane lipid metabolic process GO:0006643 76 62 0,000 0,04856184 0,05233489 ! positive regulation of protein amino acid phosphorylation GO:0001934 72 62 0,000 0,04856184 0,05231943 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 77 62 0,000 0,04856184 0,05230398 ! skeletal system morphogenesis GO:0048705 83 62 0,000 0,04856184 0,05228854 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 77 62 0,000 0,04856184 0,05227312 ! chloride channel activity GO:0005254 72 62 0,000 0,04856184 0,0522577 ! cell soma GO:0043025 68 62 0,000 0,04856184 0,05224229 ! microtubule motor activity GO:0003777 94 62 0,000 0,04856184 0,05222688 ! protein maturation by peptide bond cleavage GO:0051605 69 62 0,000 0,04856184 0,05221149 ! FAD binding GO:0050660 71 63 0,000 0,04932674 0,05301826 ! urogenital system development GO:0001655 75 63 0,000 0,04932674 0,05300264 ! regulation of synaptic transmission GO:0050804 79 63 0,000 0,04932674 0,05298703 ! aminoglycan metabolic process GO:0006022 70 63 0,000 0,04932674 0,05297143 ! cAMP-mediated signaling GO:0019933 75 63 0,000 0,04932674 0,05295584 ! amine transmembrane transporter activity GO:0005275 69 63 0,000 0,04932674 0,05294026 ! regulation of immune effector process GO:0002697 81 63 0,000 0,04932674 0,05292469 ! respiratory tube development GO:0030323 92 64 0,000 0,05009107 0,05372897 ! intracellular protein transmembrane transport GO:0065002 83 64 0,000 0,05009107 0,05371318 ! tRNA processing GO:0008033 73 64 0,000 0,05009107 0,05369739 ! negative regulation of ligase activity GO:0051352 79 64 0,000 0,05009107 0,05368162 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of myeloid cell differentiation GO:0045637 77 64 0,000 0,05009107 0,05366585 ! adaptive immune response GO:0002250 70 64 0,000 0,05009107 0,0536501 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! transition metal ion transport GO:0000041 74 64 0,000 0,05009107 0,05363435 ! neurotransmitter transport GO:0006836 72 64 0,000 0,05009107 0,05361861 ! response to unfolded protein GO:0006986 66 64 0,000 0,05009107 0,05360288 ! N-acyltransferase activity GO:0016410 70 64 0,000 0,05009107 0,05358717 ! multicellular organism reproduction GO:0032504 71 65 0,000 0,05085483 0,05438828 GO:0048609|reproductive process in a multicellular organism, ! lymphocyte differentiation GO:0030098 93 65 0,000 0,05085483 0,05437234 ! response to inorganic substance GO:0010035 71 65 0,000 0,05085483 0,05435641 ! regulation of cytokine biosynthetic process GO:0042035 84 65 0,000 0,05085483 0,05434048 ! activation of MAPK activity GO:0000187 74 65 0,000 0,05085483 0,05432457 ! gonad development GO:0008406 71 65 0,000 0,05085483 0,05430867 ! acetyltransferase activity GO:0016407 73 65 0,000 0,05085483 0,05429278 ! protein import into nucleus GO:0006606 73 66 0,000 0,05161801 0,05509143 ! developmental maturation GO:0021700 85 66 0,000 0,05161801 0,05507532 ! myeloid cell differentiation GO:0030099 78 66 0,000 0,05161801 0,05505921 ! tubulin binding GO:0015631 92 66 0,000 0,05161801 0,05504312 ! leukocyte mediated immunity GO:0002443 73 66 0,000 0,05161801 0,05502703 ! tube morphogenesis GO:0035239 84 66 0,000 0,05161801 0,05501096 ! cysteine-type endopeptidase activity GO:0004197 73 66 0,000 0,05161801 0,05499489 ! endoplasmic reticulum lumen GO:0005788 78 67 0,000 0,05238062 0,0557911 ! glycerolipid biosynthetic process GO:0045017 81 67 0,000 0,05238062 0,05577481 ! nuclear import GO:0051170 74 67 0,000 0,05238062 0,05575854 ! activation of protein kinase activity GO:0032147 83 67 0,000 0,05238062 0,05574227 ! chloride ion binding GO:0031404 79 67 0,000 0,05238062 0,05572602 ! humoral immune response GO:0006959 75 67 0,000 0,05238062 0,05570977 ! amine binding GO:0043176 77 67 0,000 0,05238062 0,05569353 ! female pregnancy GO:0007565 78 67 0,000 0,05238062 0,0556773 ! extrinsic to membrane GO:0019898 75 67 0,000 0,05238062 0,05566109 ! anion channel activity GO:0005253 77 67 0,000 0,05238062 0,05564488 ! regulation of homeostatic process GO:0032844 88 67 0,000 0,05238062 0,05562868 ! regulation of adenylate cyclase activity GO:0045761 81 68 0,000 0,05314266 0,05642154 ! amine catabolic process GO:0009310 73 68 0,000 0,05314266 0,05640513 ! negative regulation of organelle organization GO:0010639 93 68 0,000 0,05314266 0,05638872 ! monosaccharide catabolic process GO:0046365 73 68 0,000 0,05314266 0,05637232 ! respiratory system development GO:0060541 96 68 0,000 0,05314266 0,05635594 ! mRNA transport GO:0051028 88 69 0,000 0,05390413 0,05714683 ! fatty acid biosynthetic process GO:0006633 76 69 0,000 0,05390413 0,05713023 ! regulation of transmission of nerve impulse GO:0051969 87 69 0,000 0,05390413 0,05711364 ! sarcomere GO:0030017 74 69 0,000 0,05390413 0,05709705 ! exocytosis GO:0006887 76 69 0,000 0,05390413 0,05708048 ! skeletal muscle tissue development GO:0007519 75 69 0,000 0,05390413 0,05706391 GO:0060538|skeletal muscle organ development, ! nucleosome assembly GO:0006334 87 69 0,000 0,05390413 0,05704736 ! extracellular ligand-gated ion channel activity GO:0005230 82 69 0,000 0,05390413 0,05703081 ! amine biosynthetic process GO:0009309 78 70 0,000 0,05466502 0,05781908 ! thiolester hydrolase activity GO:0016790 84 70 0,000 0,05466502 0,05780232 ! early endosome GO:0005769 104 70 0,000 0,05466502 0,05778557 ! regulation of cyclase activity GO:0031279 83 70 0,000 0,05466502 0,05776883 ! regulation of lipase activity GO:0060191 78 70 0,000 0,05466502 0,0577521 ! amino acid transport GO:0006865 76 70 0,000 0,05466502 0,05773538 ! chromatin assembly GO:0031497 88 70 0,000 0,05466502 0,05771867 ! positive regulation of phosphorylation GO:0042327 82 70 0,000 0,05466502 0,05770197 ! calcium channel activity GO:0005262 86 70 0,000 0,05466502 0,05768527 ! response to protein stimulus GO:0051789 73 70 0,000 0,05466502 0,05766859 ! axon guidance GO:0007411 87 70 0,000 0,05466502 0,05765192 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 73 71 0,000 0,05542534 0,05843689 ! mitochondrial outer membrane GO:0005741 81 71 0,000 0,05542534 0,05842001 ! protein localization in nucleus GO:0034504 78 71 0,000 0,05542534 0,05840313 ! lipoprotein metabolic process GO:0042157 76 71 0,000 0,05542534 0,05838627 ! positive regulation of phosphorus metabolic process GO:0010562 85 72 0,000 0,05618509 0,05916952 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 84 72 0,000 0,05618509 0,05915245 ! steroid biosynthetic process GO:0006694 83 72 0,000 0,05618509 0,05913538 ! regulation of MAPKKK cascade GO:0043408 82 72 0,000 0,05618509 0,05911832 ! regulation of lyase activity GO:0051339 85 72 0,000 0,05618509 0,05910128 ! acute inflammatory response GO:0002526 91 72 0,000 0,05618509 0,05908424 ! apical junction complex GO:0043296 90 72 0,000 0,05618509 0,05906721 ! phospholipase activity GO:0004620 99 72 0,000 0,05618509 0,05905019 ! membrane raft GO:0045121 81 72 0,000 0,05618509 0,05903319 ! regulation of neurological system process GO:0031644 91 72 0,000 0,05618509 0,05901619 ! structural constituent of cytoskeleton GO:0005200 78 72 0,000 0,05618509 0,0589992 ! elevation of cytosolic calcium ion concentration GO:0007204 87 73 0,000 0,05694428 0,0597792 GO:0051480|cytosolic calcium ion homeostasis, ! response to drug GO:0042493 94 73 0,000 0,05694428 0,059762 ! protein transporter activity GO:0008565 80 73 0,000 0,05694428 0,05974482 ! regulation of cAMP biosynthetic process GO:0030817 86 73 0,000 0,05694428 0,05972764 ! exopeptidase activity GO:0008238 81 73 0,000 0,05694428 0,05971047 ! digestion GO:0007586 81 73 0,000 0,05694428 0,05969331 ! response to oxygen levels GO:0070482 86 74 0,000 0,05770289 0,06047117 ! potassium channel complex GO:0034705 84 74 0,000 0,05770289 0,0604538 GO:0008076|voltage-gated potassium channel complex, ! protein-DNA complex assembly GO:0065004 101 74 0,000 0,05770289 0,06043645 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 85 74 0,000 0,05770289 0,0604191 ! one-carbon metabolic process GO:0006730 84 74 0,000 0,05770289 0,06040176 ! blood coagulation GO:0007596 90 74 0,000 0,05770289 0,06038443 GO:0050817|coagulation, ! reproductive structure development GO:0048608 89 74 0,000 0,05770289 0,06036712 ! apicolateral plasma membrane GO:0016327 92 74 0,000 0,05770289 0,06034981 ! phosphoinositide-mediated signaling GO:0048015 92 74 0,000 0,05770289 0,06033251 ! cellular lipid catabolic process GO:0044242 99 74 0,000 0,05770289 0,06031523 ! ubiquitin ligase complex GO:0000151 91 74 0,000 0,05770289 0,06029795 ! cell projection part GO:0044463 80 74 0,000 0,05770289 0,06028068 ! meiosis GO:0007126 108 75 0,000 0,05846093 0,0610551 GO:0051327|M phase of meiotic cell cycle, ! regulation of DNA binding GO:0051101 94 75 0,000 0,05846093 0,06103763 ! carboxylic acid transmembrane transporter activity GO:0046943 85 75 0,000 0,05846093 0,06102016 ! regulation of cAMP metabolic process GO:0030814 88 75 0,000 0,05846093 0,06100271 ! regulation of blood pressure GO:0008217 82 75 0,000 0,05846093 0,06098527 ! transcription initiation GO:0006352 84 75 0,000 0,05846093 0,06096783 ! Ras GTPase activator activity GO:0005099 83 75 0,000 0,05846093 0,06095041 ! neuropeptide signaling pathway GO:0007218 85 76 0,000 0,0592184 0,0617225 ! defense response to bacterium GO:0042742 81 76 0,000 0,0592184 0,06170487 ! regulation of lipid metabolic process GO:0019216 98 76 0,000 0,0592184 0,06168725 ! meiotic cell cycle GO:0051321 109 76 0,000 0,0592184 0,06166964 ! regulation of neuron differentiation GO:0045664 96 76 0,000 0,0592184 0,06165204 ! protein-DNA complex GO:0032993 93 76 0,000 0,0592184 0,06163445 ! organic acid transmembrane transporter activity GO:0005342 86 76 0,000 0,0592184 0,06161687 ! development of primary sexual characteristics GO:0045137 86 76 0,000 0,0592184 0,0615993 ! cytosolic ribosome GO:0022626 82 76 0,000 0,0592184 0,06158174 ! serine-type endopeptidase inhibitor activity GO:0004867 93 76 0,000 0,0592184 0,06156419 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 84 77 0,000 0,05997531 0,06233331 ! nucleosome organization GO:0034728 96 77 0,000 0,05997531 0,06231556 ! alcohol catabolic process GO:0046164 84 77 0,000 0,05997531 0,06229781 ! vacuolar membrane GO:0005774 86 77 0,000 0,05997531 0,06228008 ! G-protein-coupled receptor binding GO:0001664 87 77 0,000 0,05997531 0,06226236 ! myofibril GO:0030016 82 77 0,000 0,05997531 0,06224464 ! protein oligomerization GO:0051259 93 77 0,000 0,05997531 0,06222694 ! phosphoric diester hydrolase activity GO:0008081 99 78 0,000 0,06073164 0,06299376 ! endonuclease activity GO:0004519 111 78 0,000 0,06073164 0,06297585 ! cofactor biosynthetic process GO:0051188 93 78 0,000 0,06073164 0,06295795 ! inorganic anion transport GO:0015698 87 78 0,000 0,06073164 0,06294007 ! regulation of protein transport GO:0051223 85 78 0,000 0,06073164 0,06292219 ! regulation of nucleotide biosynthetic process GO:0030808 91 78 0,000 0,06073164 0,06290433 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! positive regulation of protein modification process GO:0031401 100 78 0,000 0,06073164 0,06288647 ! transmembrane receptor protein kinase activity GO:0019199 95 78 0,000 0,06073164 0,06286863 ! carboxylesterase activity GO:0004091 93 78 0,000 0,06073164 0,06285079 ! protein ubiquitination GO:0016567 95 78 0,000 0,06073164 0,06283297 ! extracellular matrix structural constituent GO:0005201 96 78 0,000 0,06073164 0,06281515 ! contractile fiber part GO:0044449 83 78 0,000 0,06073164 0,06279735 ! positive regulation of MAP kinase activity GO:0043406 89 79 0,000 0,06148741 0,0635608 ! vitamin metabolic process GO:0006766 86 79 0,000 0,06148741 0,0635428 ! T cell activation GO:0042110 120 79 0,000 0,06148741 0,0635248 ! cellular response to hormone stimulus GO:0032870 94 79 0,000 0,06148741 0,06350682 ! phosphoinositide binding GO:0035091 99 79 0,000 0,06148741 0,06348884 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 88 80 0,000 0,06224261 0,06425044 ! eye development GO:0001654 93 80 0,000 0,06224261 0,06423226 ! ATP biosynthetic process GO:0006754 89 80 0,000 0,06224261 0,0642141 ! rhythmic process GO:0048511 90 80 0,000 0,06224261 0,06419594 ! regulation of catabolic process GO:0009894 87 80 0,000 0,06224261 0,0641778 ! SH3 domain binding GO:0017124 95 80 0,000 0,06224261 0,06415966 ! hemostasis GO:0007599 96 80 0,000 0,06224261 0,06414154 ! chromosome, centromeric region GO:0000775 119 80 0,000 0,06224261 0,06412343 ! regulation of cyclic nucleotide metabolic process GO:0030799 93 80 0,000 0,06224261 0,06410532 ! cholesterol metabolic process GO:0008203 91 81 0,000 0,06299725 0,06486423 ! vacuolar part GO:0044437 91 81 0,000 0,06299725 0,06484592 ! ossification GO:0001503 111 82 0,000 0,06375131 0,06560361 ! biogenic amine metabolic process GO:0006576 99 82 0,000 0,06375131 0,06558511 ! forebrain development GO:0030900 93 82 0,000 0,06375131 0,06556662 ! external side of plasma membrane GO:0009897 105 82 0,000 0,06375131 0,06554814 ! cellular respiration GO:0045333 85 82 0,000 0,06375131 0,06552967 ! heparin binding GO:0008201 108 82 0,000 0,06375131 0,06551121 ! microtubule-based movement GO:0007018 119 83 0,000 0,06450481 0,06626684 ! nuclear speck GO:0016607 99 83 0,000 0,06450481 0,06624819 ! ATP-dependent helicase activity GO:0008026 107 83 0,000 0,06450481 0,06622954 GO:0070035|purine NTP-dependent helicase activity, ! regulation of T cell activation GO:0050863 104 83 0,000 0,06450481 0,0662109 ! regulation of establishment of protein localization GO:0070201 90 83 0,000 0,06450481 0,06619228 ! oxidative phosphorylation GO:0006119 85 83 0,000 0,06450481 0,06617367 ! contractile fiber GO:0043292 88 83 0,000 0,06450481 0,06615506 ! bone development GO:0060348 112 83 0,000 0,06450481 0,06613647 ! regulation of nucleotide metabolic process GO:0006140 96 83 0,000 0,06450481 0,06611789 ! regulation of membrane potential GO:0042391 98 83 0,000 0,06450481 0,06609931 ! cilium GO:0005929 88 83 0,000 0,06450481 0,06608075 ! regulation of DNA metabolic process GO:0051052 139 84 0,000 0,06525775 0,06683331 ! regulation of defense response GO:0031347 98 84 0,000 0,06525775 0,06681455 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 94 84 0,000 0,06525775 0,06679581 ! nitrogen compound catabolic process GO:0044270 91 84 0,000 0,06525775 0,06677707 ! DNA recombination GO:0006310 147 84 0,000 0,06525775 0,06675834 ! phospholipid biosynthetic process GO:0008654 101 85 0,000 0,06601011 0,06750908 ! protein modification by small protein conjugation GO:0032446 103 85 0,000 0,06601011 0,06749016 ! monooxygenase activity GO:0004497 92 85 0,000 0,06601011 0,06747125 ! hydrogen ion transmembrane transporter activity GO:0015078 88 85 0,000 0,06601011 0,06745235 ! protein binding, bridging GO:0030674 104 85 0,000 0,06601011 0,06743346 ! negative regulation of transport GO:0051051 98 86 0,000 0,06676192 0,06818238 ! clathrin-coated vesicle GO:0030136 100 86 0,000 0,06676192 0,0681633 ! Golgi vesicle transport GO:0048193 98 86 0,000 0,06676192 0,06814423 ! lipase activity GO:0016298 114 86 0,000 0,06676192 0,06812517 ! voltage-gated potassium channel activity GO:0005249 105 86 0,000 0,06676192 0,06810612 ! leukocyte differentiation GO:0002521 118 87 0,000 0,06751315 0,06885323 ! regulation of cell morphogenesis GO:0022604 100 87 0,000 0,06751315 0,06883398 ! organelle outer membrane GO:0031968 102 88 0,000 0,06826383 0,0695799 ! carbohydrate biosynthetic process GO:0016051 95 88 0,000 0,06826383 0,06956046 ! growth factor binding GO:0019838 102 88 0,000 0,06826383 0,06954104 ! protein processing GO:0016485 100 88 0,000 0,06826383 0,06952162 ! protein tyrosine phosphatase activity GO:0004725 109 89 0,000 0,06901394 0,07026594 ! protein kinase binding GO:0019901 115 89 0,000 0,06901394 0,07024633 ! gland development GO:0048732 108 89 0,000 0,06901394 0,07022674 ! ATP metabolic process GO:0046034 100 90 0,000 0,06976348 0,07096966 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 101 90 0,000 0,06976348 0,07094987 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! peroxisome GO:0005777 100 90 0,000 0,06976348 0,0709301 GO:0042579|microbody, ! glycerophospholipid metabolic process GO:0006650 109 90 0,000 0,06976348 0,07091033 ! sterol metabolic process GO:0016125 102 90 0,000 0,06976348 0,07089058 ! negative regulation of multicellular organismal process GO:0051241 102 90 0,000 0,06976348 0,07087084 ! anion binding GO:0043168 104 90 0,000 0,06976348 0,07085111 ! amine transport GO:0015837 97 90 0,000 0,06976348 0,07083139 ! response to virus GO:0009615 109 90 0,000 0,06976348 0,07081168 ! outer membrane GO:0019867 104 90 0,000 0,06976348 0,07079199 ! extracellular matrix part GO:0044420 111 90 0,000 0,06976348 0,0707723 ! ribonucleoside triphosphate biosynthetic process GO:0009201 102 91 0,000 0,07051247 0,07151223 GO:0009142|nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 104 91 0,000 0,07051247 0,07149235 ! sulfur metabolic process GO:0006790 98 91 0,000 0,07051247 0,07147249 ! sex differentiation GO:0007548 103 91 0,000 0,07051247 0,07145263 ! hormone metabolic process GO:0042445 107 91 0,000 0,07051247 0,07143279 ! regulation of protein localization GO:0032880 99 91 0,000 0,07051247 0,07141296 ! detection of stimulus GO:0051606 100 91 0,000 0,07051247 0,07139314 ! structure-specific DNA binding GO:0043566 112 92 0,000 0,07126089 0,07213089 ! anatomical structure homeostasis GO:0060249 121 92 0,000 0,07126089 0,07211088 ! carboxylic acid catabolic process GO:0046395 100 92 0,000 0,07126089 0,07209088 GO:0016054|organic acid catabolic process, ! translation factor activity, nucleic acid binding GO:0008135 108 92 0,000 0,07126089 0,07207089 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 111 92 0,000 0,07126089 0,07205092 ! extracellular structure organization GO:0043062 119 92 0,000 0,07126089 0,07203095 ! protein import GO:0017038 102 93 0,000 0,07200874 0,07276673 ! neurotransmitter receptor activity GO:0030594 104 93 0,000 0,07200874 0,07274658 ! response to nutrient levels GO:0031667 105 93 0,000 0,07200874 0,07272644 ! Ras protein signal transduction GO:0007265 118 93 0,000 0,07200874 0,07270631 ! protein modification by small protein conjugation or removal GO:0070647 112 93 0,000 0,07200874 0,07268619 ! ATPase activity, coupled to transmembrane movement of substances GO:0042626 102 94 0,000 0,07275604 0,0734202 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 104 94 0,000 0,07275604 0,0733999 ! morphogenesis of an epithelium GO:0002009 113 94 0,000 0,07275604 0,07337961 GO:0060429|epithelium development, ! neurotransmitter binding GO:0042165 105 94 0,000 0,07275604 0,07335932 ! DNA packaging GO:0006323 113 94 0,000 0,07275604 0,07333905 ! homophilic cell adhesion GO:0007156 107 95 0,000 0,07350277 0,0740713 ! ATPase activity, coupled to movement of substances GO:0043492 104 95 0,000 0,07350277 0,07405085 ! anterior/posterior pattern formation GO:0009952 109 95 0,000 0,07350277 0,0740304 ! protein localization in organelle GO:0033365 104 95 0,000 0,07350277 0,07400997 ! immune effector process GO:0002252 110 95 0,000 0,07350277 0,07398955 ! apical plasma membrane GO:0016324 105 95 0,000 0,07350277 0,07396914 ! translational elongation GO:0006414 104 96 0,000 0,07424895 0,07469944 ! hydrolase activity, acting on glycosyl bonds GO:0016798 109 96 0,000 0,07424895 0,07467884 ! in utero embryonic development GO:0001701 110 96 0,000 0,07424895 0,07465826 ! carbohydrate catabolic process GO:0016052 116 96 0,000 0,07424895 0,07463768 ! receptor complex GO:0043235 131 96 0,000 0,07424895 0,07461712 ! regulation of response to external stimulus GO:0032101 109 96 0,000 0,07424895 0,07459657 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 100 96 0,000 0,07424895 0,07457603 ! electron transport chain GO:0022900 104 97 0,000 0,07499456 0,0753042 ! metalloendopeptidase activity GO:0004222 126 97 0,000 0,07499456 0,07528347 ! perinuclear region of cytoplasm GO:0048471 125 97 0,000 0,07499456 0,07526276 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances GO:0016820 105 97 0,000 0,07499456 0,07524206 ! carboxylic acid binding GO:0031406 108 97 0,000 0,07499456 0,07522138 ! protein maturation GO:0051604 109 97 0,000 0,07499456 0,0752007 ! intermediate filament GO:0005882 102 98 0,000 0,07573961 0,07592693 GO:0045111|intermediate filament cytoskeleton, ! UDP-glycosyltransferase activity GO:0008194 120 98 0,000 0,07573961 0,07590607 ! cell fate commitment GO:0045165 118 98 0,000 0,07573961 0,07588522 ! negative regulation of cellular component organization GO:0051129 132 99 0,000 0,0764841 0,0766101 ! hormone activity GO:0005179 113 99 0,000 0,0764841 0,07658907 ! solute:cation symporter activity GO:0015294 110 99 0,000 0,0764841 0,07656805 ! unfolded protein binding GO:0051082 118 100 0,000 0,07722803 0,07729159 ! regulation of neurogenesis GO:0050767 123 100 0,000 0,07722803 0,07727039 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016810 105 100 0,000 0,07722803 0,0772492 ! peptide receptor activity, G-protein coupled GO:0008528 107 100 0,000 0,07722803 0,07722803