pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/1211-1-real-Zhou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL4685_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 3,173E-05 0,07530661 ! regulation of cyclin-dependent protein kinase activity GO:0000079 86 53 2,000 3,943E-05 0,04678625 ! negative regulation of JAK-STAT cascade GO:0046426 18 8 1,000 4,228E-05 0,03344381 ! thymus development GO:0048538 19 11 1,000 8,286E-05 0,04915606 ! T cell homeostasis GO:0043029 22 12 1,000 9,935E-05 0,04715345 ! lymphocyte homeostasis GO:0002260 29 15 1,000 1,577E-04 0,06236964 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 1,000 2,293E-04 0,0777185 ! cellular response to unfolded protein GO:0034620 24 18 1,000 2,293E-04 0,06800369 GO:0030968|endoplasmic reticulum unfolded protein response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 32 21 1,000 3,139E-04 0,08277588 ! response to endoplasmic reticulum stress GO:0034976 32 24 1,000 4,117E-04 0,097686 ! leukocyte homeostasis GO:0001776 40 25 1,000 4,471E-04 0,09645333 ! ER-nuclear signaling pathway GO:0006984 33 26 1,000 4,84E-04 0,09570976 ! fat cell differentiation GO:0045444 41 27 1,000 5,223E-04 0,09534181 ! negative regulation of protein kinase cascade GO:0010741 58 30 1,000 6,458E-04 0,10946553 ! spindle organization GO:0007051 39 33 1,000 7,821E-04 0,12372446 ! regulation of Wnt receptor signaling pathway GO:0030111 57 34 1,000 8,303E-04 0,12314631 ! meiosis I GO:0007127 61 36 1,000 9,31E-04 0,12995753 ! endosome transport GO:0016197 74 42 1,000 1,267E-03 0,16696861 ! response to calcium ion GO:0051592 65 43 1,000 1,327E-03 0,16576931 ! G1/S transition of mitotic cell cycle GO:0000082 93 44 1,000 1,389E-03 0,16485303 ! positive regulation of cell cycle GO:0045787 83 45 1,000 1,453E-03 0,16417897 ! regulation of JAK-STAT cascade GO:0046425 68 46 1,000 1,518E-03 0,16371375 ! response to UV GO:0009411 79 47 1,000 1,584E-03 0,16342979 ! cytokine-mediated signaling pathway GO:0019221 77 53 1,000 2,01E-03 0,19873165 ! regulation of protein catabolic process GO:0042176 83 55 1,000 2,163E-03 0,20528044 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 96 66 1,000 3,098E-03 0,28271109 ! meiosis GO:0007126 110 68 1,000 3,285E-03 0,28867651 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of protein amino acid phosphorylation GO:0001934 103 68 1,000 3,285E-03 0,27836663 ! meiotic cell cycle GO:0051321 111 69 1,000 3,38E-03 0,27657812 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 104 70 1,000 3,477E-03 0,27501098 ! homeostasis of number of cells GO:0048872 109 72 1,000 3,674E-03 0,28124581 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 108 73 1,000 3,775E-03 0,27991662 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 110 73 1,000 3,775E-03 0,2714343 ! positive regulation of phosphorylation GO:0042327 119 75 1,000 3,98E-03 0,27776035 ! regulation of catabolic process GO:0009894 114 75 1,000 3,98E-03 0,26982434 ! response to metal ion GO:0010038 114 76 1,000 4,084E-03 0,26921237 ! phosphoinositide-mediated signaling GO:0048015 122 76 1,000 4,084E-03 0,26193636 ! positive regulation of ligase activity GO:0051351 114 76 1,000 4,084E-03 0,25504329 ! positive regulation of phosphorus metabolic process GO:0010562 125 77 1,000 4,19E-03 0,25493464 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of ubiquitin-protein ligase activity GO:0051438 123 79 1,000 4,405E-03 0,26132675 ! response to unfolded protein GO:0006986 113 80 1,000 4,514E-03 0,26128949 ! response to inorganic substance GO:0010035 127 81 1,000 4,625E-03 0,26132503 ! regulation of ligase activity GO:0051340 129 82 1,000 4,737E-03 0,26142811 ! positive regulation of protein modification process GO:0031401 126 83 1,000 4,85E-03 0,26159398 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 130 85 1,000 5,081E-03 0,26792144 GO:0010498|proteasomal protein catabolic process, ! response to protein stimulus GO:0051789 127 85 1,000 5,081E-03 0,26209706 ! Golgi vesicle transport GO:0048193 145 87 1,000 5,316E-03 0,26839534 ! interphase of mitotic cell cycle GO:0051329 166 87 1,000 5,316E-03 0,26280377 ! interphase GO:0051325 169 89 1,000 5,556E-03 0,26906993 ! microtubule cytoskeleton organization GO:0000226 133 90 1,000 5,678E-03 0,2694746 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 6,27E-03 0,29174148 ! positive regulation of protein ubiquitination GO:0031398 8 5 0,000 6,27E-03 0,28613107 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 6,27E-03 0,28073237 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 5 0,000 6,27E-03 0,27553362 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 6,27E-03 0,27052392 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! negative regulation of tyrosine phosphorylation of Stat3 protein GO:0042518 13 5 0,000 6,27E-03 0,26569313 GO:0042532|negative regulation of tyrosine phosphorylation of STAT protein, ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,27E-03 0,26103185 ! regulation of cGMP biosynthetic process GO:0030826 7 5 0,000 6,27E-03 0,2565313 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 6,27E-03 0,25218331 ! positive regulation of actin filament polymerization GO:0030838 8 5 0,000 6,27E-03 0,24798026 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 7 5 0,000 6,27E-03 0,24391501 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 6,27E-03 0,2399809 ! response to oxygen radical GO:0000305 11 5 0,000 6,27E-03 0,23617167 ! negative regulation of bone resorption GO:0045779 11 5 0,000 6,27E-03 0,23248149 ! myoblast cell fate commitment GO:0048625 8 5 0,000 6,27E-03 0,22890485 ! nucleotide-sugar transport GO:0015780 8 5 0,000 6,27E-03 0,2254366 ! positive regulation of lipid biosynthetic process GO:0046889 7 5 0,000 6,27E-03 0,22207187 ! regulation of interferon-beta production GO:0032648 5 5 0,000 6,27E-03 0,21880611 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 6 5 0,000 6,27E-03 0,21563501 GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 6 5 0,000 6,27E-03 0,21255451 ! female meiosis GO:0007143 8 5 0,000 6,27E-03 0,20956078 ! nose development GO:0043584 10 5 0,000 6,27E-03 0,20665022 ! DNA catabolic process, exonucleolytic GO:0000738 7 5 0,000 6,27E-03 0,20381939 ! regulation of cell adhesion mediated by integrin GO:0033628 15 5 0,000 6,27E-03 0,20106507 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 6,27E-03 0,19838421 ! short-chain fatty acid metabolic process GO:0046459 8 5 0,000 6,27E-03 0,19577389 ! tryptophanyl-tRNA aminoacylation GO:0006436 6 5 0,000 6,27E-03 0,19323137 ! cobalt ion transport GO:0006824 9 5 0,000 6,27E-03 0,19075404 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 6,27E-03 0,18833944 ! SMAD protein complex assembly GO:0007183 10 5 0,000 6,27E-03 0,18598519 ! phospholipid dephosphorylation GO:0046839 7 5 0,000 6,27E-03 0,18368908 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 6,27E-03 0,18144897 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 6,27E-03 0,17926284 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 6,27E-03 0,17712876 ! adaptation of signaling pathway GO:0022401 9 5 0,000 6,27E-03 0,17504489 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! cardiac muscle cell proliferation GO:0060038 7 5 0,000 6,27E-03 0,17300948 GO:0014855|striated muscle cell proliferation, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 6,27E-03 0,17102087 ! negative regulation of gene-specific transcription GO:0032582 10 5 0,000 6,27E-03 0,16907745 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 6,27E-03 0,1671777 ! negative regulation of histone modification GO:0031057 7 5 0,000 6,27E-03 0,16532017 ! malate metabolic process GO:0006108 8 5 0,000 6,27E-03 0,16350347 ! positive regulation of histone modification GO:0031058 6 5 0,000 6,27E-03 0,16172626 ! transcription from mitochondrial promoter GO:0006390 8 5 0,000 6,27E-03 0,15998726 ! clathrin coat assembly GO:0048268 11 5 0,000 6,27E-03 0,15828527 ! Notch receptor processing GO:0007220 8 5 0,000 6,27E-03 0,15661911 ! phototransduction, visible light GO:0007603 7 5 0,000 6,27E-03 0,15498766 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,27E-03 0,15338985 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 6,27E-03 0,15182465 ! mating behavior GO:0007617 6 5 0,000 6,27E-03 0,15029107 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 6,27E-03 0,14878815 ! copulation GO:0007620 8 5 0,000 6,27E-03 0,147315 ! protein maturation by protein folding GO:0022417 13 5 0,000 6,27E-03 0,14587074 ! embryonic hemopoiesis GO:0035162 13 5 0,000 6,27E-03 0,14445452 ! regulation of potassium ion transport GO:0043266 9 5 0,000 6,27E-03 0,14306553 ! apoptotic cell clearance GO:0043277 14 5 0,000 6,27E-03 0,141703 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 9 5 0,000 6,27E-03 0,14036618 ! lipoprotein particle clearance GO:0034381 9 5 0,000 6,27E-03 0,13905435 ! fructose 1,6-bisphosphate metabolic process GO:0030388 8 5 0,000 6,27E-03 0,13776681 ! regulation of smooth muscle cell apoptosis GO:0034391 8 5 0,000 6,27E-03 0,13650289 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 6,27E-03 0,13526196 GO:0046329|negative regulation of JNK cascade, ! oocyte maturation GO:0001556 6 5 0,000 6,27E-03 0,13404338 ! response to axon injury GO:0048678 8 5 0,000 6,27E-03 0,13284657 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,27E-03 0,13167093 ! response to protozoan GO:0001562 10 5 0,000 6,27E-03 0,13051593 ! negative regulation of heart contraction GO:0045822 12 5 0,000 6,27E-03 0,129381 ! lymph vessel development GO:0001945 8 5 0,000 6,27E-03 0,12826565 ! regulation of activin receptor signaling pathway GO:0032925 11 5 0,000 6,27E-03 0,12716936 ! endochondral ossification GO:0001958 13 5 0,000 6,27E-03 0,12609166 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 6,27E-03 0,12503206 ! single strand break repair GO:0000012 5 5 0,000 6,27E-03 0,12399013 ! parathyroid gland development GO:0060017 8 5 0,000 6,27E-03 0,12296542 ! anagen GO:0042640 7 5 0,000 6,27E-03 0,1219575 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 6,27E-03 0,12096598 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 6,27E-03 0,11999045 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 6,27E-03 0,11903052 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 8 5 0,000 6,27E-03 0,11808584 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 8 5 0,000 6,27E-03 0,11715603 ! smooth muscle tissue development GO:0048745 14 5 0,000 6,27E-03 0,11624075 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,27E-03 0,11533965 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 6,27E-03 0,11445243 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 6,27E-03 0,11357874 ! cardiac muscle fiber development GO:0048739 8 5 0,000 6,27E-03 0,1127183 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,27E-03 0,11187079 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 8 5 0,000 6,27E-03 0,11103594 ! neutrophil mediated immunity GO:0002446 6 5 0,000 6,27E-03 0,11021345 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 6,27E-03 0,10940306 ! regulation of oligodendrocyte differentiation GO:0048713 15 5 0,000 6,27E-03 0,10860449 GO:0048715|negative regulation of oligodendrocyte differentiation, ! mitochondrion localization, microtubule-mediated GO:0034643 9 5 0,000 6,27E-03 0,1078175 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! negative regulation of RNA splicing GO:0033119 6 5 0,000 6,27E-03 0,10704184 ! ionotropic glutamate receptor signaling pathway GO:0035235 10 5 0,000 6,27E-03 0,10627725 ! positive regulation of isotype switching to IgG isotypes GO:0048304 8 5 0,000 6,27E-03 0,10552351 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 6,27E-03 0,10478039 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 9 5 0,000 6,27E-03 0,10404766 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 6,27E-03 0,10332511 ! tyrosine catabolic process GO:0006572 7 5 0,000 6,27E-03 0,10261252 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 6,27E-03 0,1019097 ! proline biosynthetic process GO:0006561 6 5 0,000 6,27E-03 0,10121643 ! L-serine biosynthetic process GO:0006564 6 5 0,000 6,27E-03 0,10053254 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 6,27E-03 0,09985782 ! polyol catabolic process GO:0046174 7 5 0,000 6,27E-03 0,0991921 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 6,27E-03 0,0985352 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 6,27E-03 0,09788694 ! sister chromatid cohesion GO:0007062 10 5 0,000 6,27E-03 0,09724716 ! response to ATP GO:0033198 6 5 0,000 6,27E-03 0,09661569 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 9 5 0,000 6,27E-03 0,09599236 ! positive regulation of stress fiber formation GO:0051496 15 5 0,000 6,27E-03 0,09537702 ! neutrophil activation GO:0042119 6 5 0,000 6,27E-03 0,09476953 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 6,27E-03 0,09416972 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 6,27E-03 0,09357746 ! response to food GO:0032094 5 5 0,000 6,27E-03 0,0929926 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 6,27E-03 0,092415 GO:0043088|regulation of Cdc42 GTPase activity, ! positive regulation of transporter activity GO:0032411 5 5 0,000 6,27E-03 0,09184454 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 8 5 0,000 6,27E-03 0,09128108 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,27E-03 0,09072448 ! paraxial mesoderm development GO:0048339 9 5 0,000 6,27E-03 0,09017464 ! forebrain neuron development GO:0021884 7 5 0,000 6,27E-03 0,08963142 ! melanosome organization GO:0032438 7 5 0,000 6,27E-03 0,0890947 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 6,27E-03 0,08856438 ! virus-infected cell apoptosis GO:0006926 8 5 0,000 6,27E-03 0,08804033 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 6,27E-03 0,08752244 ! positive regulation of neuroblast proliferation GO:0002052 9 5 0,000 6,27E-03 0,08701062 ! mesodermal cell fate determination GO:0007500 7 5 0,000 6,27E-03 0,08650474 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,27E-03 0,08600471 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 8 5 0,000 6,27E-03 0,08551043 ! nucleoside salvage GO:0043174 7 5 0,000 6,27E-03 0,0850218 GO:0006166|purine ribonucleoside salvage, ! lipid glycosylation GO:0030259 6 5 0,000 6,27E-03 0,08453872 ! attachment of GPI anchor to protein GO:0016255 10 5 0,000 6,27E-03 0,0840611 ! negative regulation of platelet activation GO:0010544 8 5 0,000 6,27E-03 0,08358885 GO:0010543|regulation of platelet activation, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 6,27E-03 0,08312187 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 6,27E-03 0,08266009 ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 6,27E-03 0,0822034 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of fatty acid metabolic process GO:0045923 6 5 0,000 6,27E-03 0,08175173 ! early endosome to late endosome transport GO:0045022 11 5 0,000 6,27E-03 0,081305 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 6 5 0,000 6,27E-03 0,08086313 ! depyrimidination GO:0045008 8 5 0,000 6,27E-03 0,08042603 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,27E-03 0,07999363 ! 5S class rRNA transcription GO:0042791 8 5 0,000 6,27E-03 0,07956586 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 5 0,000 6,27E-03 0,07914264 ! neuronal ion channel clustering GO:0045161 8 5 0,000 6,27E-03 0,07872389 ! sodium ion homeostasis GO:0055078 6 5 0,000 6,27E-03 0,07830956 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 6,27E-03 0,07789956 ! monocyte differentiation GO:0030224 7 5 0,000 6,27E-03 0,07749383 ! negative regulation of peptide secretion GO:0002792 8 5 0,000 6,27E-03 0,07709231 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 6 5 0,000 6,27E-03 0,07669493 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 6,27E-03 0,07630162 ! response to UV-C GO:0010225 7 5 0,000 6,27E-03 0,07591232 ! protein targeting to vacuole GO:0006623 6 5 0,000 6,27E-03 0,07552698 ! activated T cell proliferation GO:0050798 7 5 0,000 6,27E-03 0,07514553 ! negative regulation of alpha-beta T cell activation GO:0046636 7 5 0,000 6,27E-03 0,07476792 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! regulation of alpha-beta T cell proliferation GO:0046640 13 5 0,000 6,27E-03 0,07439408 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 6,27E-03 0,07402396 ! regulation of integrin biosynthetic process GO:0045113 9 5 0,000 6,27E-03 0,0736575 ! regulation of killing of cells of another organism GO:0051709 6 5 0,000 6,27E-03 0,07329466 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 6,27E-03 0,07293537 ! lymphoid progenitor cell differentiation GO:0002320 12 5 0,000 6,27E-03 0,07257959 ! positive regulation of T cell cytokine production GO:0002726 9 5 0,000 6,27E-03 0,07222726 GO:0032743|positive regulation of interleukin-2 production, ! L-ascorbic acid metabolic process GO:0019852 7 5 0,000 6,27E-03 0,07187834 ! base-excision repair, DNA ligation GO:0006288 5 5 0,000 6,27E-03 0,07153277 ! response to cadmium ion GO:0046686 8 5 0,000 6,27E-03 0,0711905 ! melanosome transport GO:0032402 8 5 0,000 6,27E-03 0,0708515 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 6,27E-03 0,07051571 ! regulation of acetylcholine secretion GO:0014056 10 5 0,000 6,27E-03 0,07018309 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 6,27E-03 0,06985359 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 6,27E-03 0,06952718 ! positive T cell selection GO:0043368 10 5 0,000 6,27E-03 0,06920379 ! purine deoxyribonucleotide catabolic process GO:0009155 6 5 0,000 6,27E-03 0,06888341 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 6,27E-03 0,06856597 ! regulation of interleukin-1 production GO:0032652 8 5 0,000 6,27E-03 0,06825145 ! ribosomal subunit assembly GO:0042257 5 5 0,000 6,27E-03 0,0679398 ! base conversion or substitution editing GO:0016553 6 5 0,000 6,27E-03 0,06763098 ! regulation of chondrocyte differentiation GO:0032330 9 5 0,000 6,27E-03 0,06732496 ! negative regulation of monooxygenase activity GO:0032769 10 5 0,000 6,27E-03 0,06702169 ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 6,27E-03 0,06672115 ! positive regulation of interleukin-12 production GO:0032735 5 5 0,000 6,27E-03 0,06642328 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 6,27E-03 0,06612807 ! histone demethylation GO:0016577 10 5 0,000 6,27E-03 0,06583547 ! mitotic recombination GO:0006312 10 5 0,000 6,27E-03 0,06554544 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 5 0,000 6,27E-03 0,06525796 ! regulation of sterol transport GO:0032371 7 5 0,000 6,27E-03 0,06497299 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 6,27E-03 0,0646905 ! sympathetic nervous system development GO:0048485 13 5 0,000 6,27E-03 0,06441046 ! enteric nervous system development GO:0048484 9 5 0,000 6,27E-03 0,06413283 ! oxygen homeostasis GO:0032364 8 5 0,000 6,27E-03 0,06385758 ! establishment of planar polarity GO:0001736 7 5 0,000 6,27E-03 0,06358468 ! lymphocyte costimulation GO:0031294 12 5 0,000 6,27E-03 0,06331411 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 6 5 0,000 6,27E-03 0,06304583 ! transcription termination GO:0006353 8 5 0,000 6,27E-03 0,06277981 ! plasminogen activation GO:0031639 5 5 0,000 6,27E-03 0,06251603 ! B cell homeostasis GO:0001782 12 5 0,000 6,27E-03 0,06225446 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 6,27E-03 0,06199506 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 6,27E-03 0,06173782 ! regulation of hair follicle development GO:0051797 9 5 0,000 6,27E-03 0,06148271 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 6,27E-03 0,06122969 ! apical protein localization GO:0045176 8 5 0,000 6,27E-03 0,06097875 ! definitive hemopoiesis GO:0060216 5 5 0,000 6,27E-03 0,06072986 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 6,27E-03 0,06048299 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 6,27E-03 0,06023812 ! glucocorticoid biosynthetic process GO:0006704 6 5 0,000 6,27E-03 0,05999522 ! regulation of keratinocyte differentiation GO:0045616 7 5 0,000 6,27E-03 0,05975428 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 6,27E-03 0,05951526 ! regulation of centrosome duplication GO:0010824 6 5 0,000 6,27E-03 0,05927815 ! disaccharide metabolic process GO:0005984 9 5 0,000 6,27E-03 0,05904292 ! galactolipid metabolic process GO:0019374 8 5 0,000 6,27E-03 0,05880955 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 6,27E-03 0,05857801 GO:0033015|tetrapyrrole catabolic process, ! positive regulation of T cell mediated cytotoxicity GO:0001916 11 5 0,000 6,27E-03 0,0583483 ! determination of adult lifespan GO:0008340 8 5 0,000 6,27E-03 0,05812037 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 6,27E-03 0,05789422 ! ectodermal gut morphogenesis GO:0048567 6 5 0,000 6,27E-03 0,05766983 GO:0007439|ectodermal gut development, ! somatic stem cell maintenance GO:0035019 14 5 0,000 6,27E-03 0,05744716 ! T cell activation during immune response GO:0002286 9 5 0,000 6,27E-03 0,05722621 ! negative regulation of fibrinolysis GO:0051918 9 5 0,000 6,27E-03 0,05700696 ! negative regulation of lipase activity GO:0060192 7 5 0,000 6,27E-03 0,05678937 ! establishment of apical/basal cell polarity GO:0035089 7 5 0,000 6,27E-03 0,05657344 ! neural plate development GO:0001840 7 5 0,000 6,27E-03 0,05635915 ! regulation of sensory perception GO:0051931 6 5 0,000 6,27E-03 0,05614647 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 10 5 0,000 6,27E-03 0,0559354 ! regulation of histone acetylation GO:0035065 7 5 0,000 6,27E-03 0,0557259 ! sensory cilium assembly GO:0035058 6 5 0,000 6,27E-03 0,05551797 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 14 5 0,000 6,27E-03 0,05531158 ! diacylglycerol metabolic process GO:0046339 8 5 0,000 6,27E-03 0,05510672 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 6,27E-03 0,05490338 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 11 5 0,000 6,27E-03 0,05470153 ! negative regulation of smooth muscle contraction GO:0045986 10 5 0,000 6,27E-03 0,05450116 ! receptor biosynthetic process GO:0032800 6 5 0,000 6,27E-03 0,05430225 ! penetration of zona pellucida GO:0007341 9 5 0,000 6,27E-03 0,05410478 ! drug metabolic process GO:0017144 5 5 0,000 6,27E-03 0,05390875 ! protein amino acid prenylation GO:0018346 9 5 0,000 6,27E-03 0,05371414 ! organ regeneration GO:0031100 7 5 0,000 6,27E-03 0,05352092 ! carnitine metabolic process GO:0009437 5 5 0,000 6,27E-03 0,05332909 GO:0006577|betaine metabolic process, ! tRNA transcription GO:0009304 11 6 0,000 7,52E-03 0,0637279 ! negative regulation of S phase of mitotic cell cycle GO:0045749 13 6 0,000 7,52E-03 0,06350111 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 7,52E-03 0,06327593 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 8 6 0,000 7,52E-03 0,06305234 ! regulation of helicase activity GO:0051095 11 6 0,000 7,52E-03 0,06283032 ! regulation of cGMP metabolic process GO:0030823 8 6 0,000 7,52E-03 0,06260987 ! sleep GO:0030431 13 6 0,000 7,52E-03 0,06239095 ! positive regulation of axon extension GO:0045773 10 6 0,000 7,52E-03 0,06217356 ! negative regulation of small GTPase mediated signal transduction GO:0051058 11 6 0,000 7,52E-03 0,06195768 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 7,52E-03 0,06174329 ! forebrain regionalization GO:0021871 7 6 0,000 7,52E-03 0,06153039 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 7,52E-03 0,06131894 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 7,52E-03 0,06110895 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 7,52E-03 0,06090038 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 7,52E-03 0,06069324 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 18 6 0,000 7,52E-03 0,0604875 ! regulation of protein export from nucleus GO:0046825 8 6 0,000 7,52E-03 0,06028315 ! neuron adhesion GO:0007158 9 6 0,000 7,52E-03 0,06008018 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 7,52E-03 0,05987856 ! signal peptide processing GO:0006465 8 6 0,000 7,52E-03 0,0596783 ! embryonic camera-type eye development GO:0031076 11 6 0,000 7,52E-03 0,05947937 GO:0048596|embryonic camera-type eye morphogenesis, ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 7,52E-03 0,05928177 ! glucocorticoid receptor signaling pathway GO:0042921 11 6 0,000 7,52E-03 0,05908547 GO:0031958|corticosteroid receptor signaling pathway, ! citrate metabolic process GO:0006101 10 6 0,000 7,52E-03 0,05889047 ! fibril organization GO:0043206 13 6 0,000 7,52E-03 0,05869675 ! regulation of mitochondrial membrane permeability GO:0046902 12 6 0,000 7,52E-03 0,0585043 ! neurofilament cytoskeleton organization GO:0060052 10 6 0,000 7,52E-03 0,05831311 ! posttranscriptional gene silencing by RNA GO:0035194 14 6 0,000 7,52E-03 0,05812317 GO:0016441|posttranscriptional gene silencing, ! behavioral response to pain GO:0048266 10 6 0,000 7,52E-03 0,05793446 ! protein refolding GO:0042026 13 6 0,000 7,52E-03 0,05774697 ! metabotropic glutamate receptor signaling pathway GO:0007216 8 6 0,000 7,52E-03 0,05756068 ! rhythmic behavior GO:0007622 14 6 0,000 7,52E-03 0,0573756 ! glial cell fate commitment GO:0021781 17 6 0,000 7,52E-03 0,05719171 ! erythrocyte maturation GO:0043249 7 6 0,000 7,52E-03 0,05700898 ! sensory perception of temperature stimulus GO:0050951 12 6 0,000 7,52E-03 0,05682743 ! protein amino acid dealkylation GO:0008214 12 6 0,000 7,52E-03 0,05664702 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 7,52E-03 0,05646776 ! regulation of odontogenesis GO:0042481 8 6 0,000 7,52E-03 0,05628963 ! mechanosensory behavior GO:0007638 8 6 0,000 7,52E-03 0,05611262 ! ovulation from ovarian follicle GO:0001542 7 6 0,000 7,52E-03 0,05593672 ! negative regulation of endocytosis GO:0045806 8 6 0,000 7,52E-03 0,05576191 ! response to interferon-gamma GO:0034341 12 6 0,000 7,52E-03 0,0555882 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 7,52E-03 0,05541557 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 9 6 0,000 7,52E-03 0,055244 ! negative regulation of viral genome replication GO:0045071 8 6 0,000 7,52E-03 0,05507349 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 6 6 0,000 7,52E-03 0,05490404 ! spinal cord dorsal/ventral patterning GO:0021513 8 6 0,000 7,52E-03 0,05473562 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 17 6 0,000 7,52E-03 0,05456823 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 11 6 0,000 7,52E-03 0,05440187 ! cGMP-mediated signaling GO:0019934 11 6 0,000 7,52E-03 0,05423651 ! activation of MAPKKK activity GO:0000185 11 6 0,000 7,52E-03 0,05407216 ! inositol phosphate-mediated signaling GO:0048016 10 6 0,000 7,52E-03 0,0539088 ! protein lipoylation GO:0009249 10 6 0,000 7,52E-03 0,05374642 ! pigment granule organization GO:0048753 11 6 0,000 7,52E-03 0,05358502 ! drug transport GO:0015893 6 6 0,000 7,52E-03 0,05342459 ! transepithelial chloride transport GO:0030321 10 6 0,000 7,52E-03 0,05326511 GO:0070633|transepithelial transport, ! cysteine metabolic process GO:0006534 8 6 0,000 7,52E-03 0,05310658 ! negative regulation of survival gene product expression GO:0008634 9 6 0,000 7,52E-03 0,052949 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 7,52E-03 0,05279234 ! regulation of defense response to virus by host GO:0050691 7 6 0,000 7,52E-03 0,05263661 ! glutamate catabolic process GO:0006538 11 6 0,000 7,52E-03 0,0524818 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 7,52E-03 0,0523279 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 7,52E-03 0,05217489 ! adenohypophysis development GO:0021984 10 6 0,000 7,52E-03 0,05202278 ! response to pH GO:0009268 10 6 0,000 7,52E-03 0,05187155 ! hyperosmotic response GO:0006972 9 6 0,000 7,52E-03 0,05172119 ! microtubule nucleation GO:0007020 10 6 0,000 7,52E-03 0,05157171 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 6 0,000 7,52E-03 0,05142309 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 6 0,000 7,52E-03 0,05127532 ! melanin biosynthetic process from tyrosine GO:0006583 9 6 0,000 7,52E-03 0,0511284 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 7,52E-03 0,05098232 ! vascular smooth muscle contraction GO:0014829 11 6 0,000 7,52E-03 0,05083707 ! regulation of retinoic acid receptor signaling pathway GO:0048385 13 6 0,000 7,52E-03 0,05069265 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 7,52E-03 0,05054904 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 7,52E-03 0,05040625 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 7,52E-03 0,05026426 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 7,52E-03 0,05012307 ! purine salvage GO:0043101 9 6 0,000 7,52E-03 0,04998267 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 7,52E-03 0,04984305 ! peptidyl-threonine phosphorylation GO:0018107 16 6 0,000 7,52E-03 0,04970421 ! nucleoside transport GO:0015858 7 6 0,000 7,52E-03 0,04956615 ! organic alcohol transport GO:0015850 9 6 0,000 7,52E-03 0,04942884 ! T cell mediated immunity GO:0002456 12 6 0,000 7,52E-03 0,0492923 ! folic acid transport GO:0015884 11 6 0,000 7,52E-03 0,04915651 ! male sex determination GO:0030238 11 6 0,000 7,52E-03 0,04902146 ! carnitine transport GO:0015879 8 6 0,000 7,52E-03 0,04888716 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 7,52E-03 0,04875359 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,52E-03 0,04862074 ! negative regulation of DNA recombination GO:0045910 10 6 0,000 7,52E-03 0,04848862 ! positive regulation of exocytosis GO:0045921 9 6 0,000 7,52E-03 0,04835721 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 7,52E-03 0,04822652 ! parturition GO:0007567 13 6 0,000 7,52E-03 0,04809653 ! determination of anterior/posterior axis, embryo GO:0008595 10 6 0,000 7,52E-03 0,04796724 GO:0007351|tripartite regional subdivision, ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 7,52E-03 0,04783864 ! lipopolysaccharide biosynthetic process GO:0009103 6 6 0,000 7,52E-03 0,04771073 ! regulation of centrosome cycle GO:0046605 8 6 0,000 7,52E-03 0,0475835 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 7,52E-03 0,04745695 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 7,52E-03 0,04733107 ! regulation of cholesterol biosynthetic process GO:0045540 8 6 0,000 7,52E-03 0,04720585 ! homeostasis of number of cells within a tissue GO:0048873 10 6 0,000 7,52E-03 0,0470813 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 7,52E-03 0,0469574 ! negative regulation of gliogenesis GO:0014014 17 6 0,000 7,52E-03 0,04683415 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 10 6 0,000 7,52E-03 0,04671155 ! neural nucleus development GO:0048857 12 6 0,000 7,52E-03 0,04658959 ! forebrain morphogenesis GO:0048853 14 6 0,000 7,52E-03 0,04646826 ! hyaluronan metabolic process GO:0030212 7 6 0,000 7,52E-03 0,04634756 ! purine base biosynthetic process GO:0009113 14 6 0,000 7,52E-03 0,04622749 ! interaction with symbiont GO:0051702 9 6 0,000 7,52E-03 0,04610804 ! regulation of dendrite development GO:0050773 13 6 0,000 7,52E-03 0,04598921 ! anterograde axon cargo transport GO:0008089 9 6 0,000 7,52E-03 0,04587098 ! positive regulation of organ growth GO:0046622 7 6 0,000 7,52E-03 0,04575336 ! eating behavior GO:0042755 6 6 0,000 7,52E-03 0,04563635 ! regulation of T cell cytokine production GO:0002724 11 6 0,000 7,52E-03 0,04551993 ! transcription-coupled nucleotide-excision repair GO:0006283 7 6 0,000 7,52E-03 0,0454041 ! response to copper ion GO:0046688 9 6 0,000 7,52E-03 0,04528886 ! negative regulation of lymphocyte mediated immunity GO:0002707 13 6 0,000 7,52E-03 0,04517421 GO:0002704|negative regulation of leukocyte mediated immunity, ! response to exogenous dsRNA GO:0043330 8 6 0,000 7,52E-03 0,04506013 ! establishment of melanosome localization GO:0032401 9 6 0,000 7,52E-03 0,04494663 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,52E-03 0,0448337 ! negative regulation of protein kinase B signaling cascade GO:0051898 12 6 0,000 7,52E-03 0,04472133 ! positive regulation of B cell differentiation GO:0045579 10 6 0,000 7,52E-03 0,04460953 ! regulation of dopamine secretion GO:0014059 14 6 0,000 7,52E-03 0,04449828 ! nucleoside catabolic process GO:0009164 7 6 0,000 7,52E-03 0,04438759 ! hair follicle maturation GO:0048820 8 6 0,000 7,52E-03 0,04427745 ! cranial nerve morphogenesis GO:0021602 7 6 0,000 7,52E-03 0,04416785 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 7,52E-03 0,0440588 ! positive regulation of interleukin-5 production GO:0032754 9 6 0,000 7,52E-03 0,04395028 GO:0032736|positive regulation of interleukin-13 production, ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 7,52E-03 0,04384229 ! rhombomere development GO:0021546 6 6 0,000 7,52E-03 0,04373483 ! positive regulation of Rho GTPase activity GO:0032321 12 6 0,000 7,52E-03 0,0436279 ! G2 phase GO:0051319 15 6 0,000 7,52E-03 0,04352149 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 10 6 0,000 7,52E-03 0,0434156 GO:0050000|chromosome localization, ! regulation of mast cell activation GO:0033003 7 6 0,000 7,52E-03 0,04331022 ! muscle cell proliferation GO:0033002 9 6 0,000 7,52E-03 0,04320536 ! membrane to membrane docking GO:0022614 12 6 0,000 7,52E-03 0,043101 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 10 6 0,000 7,52E-03 0,04299714 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 12 6 0,000 7,52E-03 0,04289378 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 6 0,000 7,52E-03 0,04279092 ! receptor internalization GO:0031623 9 6 0,000 7,52E-03 0,04268855 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 7,52E-03 0,04258666 GO:0031272|regulation of pseudopodium assembly, ! regulation of respiratory burst GO:0060263 9 6 0,000 7,52E-03 0,04248527 ! coenzyme A metabolic process GO:0015936 9 6 0,000 7,52E-03 0,04238435 ! myeloid dendritic cell activation GO:0001773 11 6 0,000 7,52E-03 0,04228392 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 12 6 0,000 7,52E-03 0,04218395 ! peptidyl-histidine modification GO:0018202 10 6 0,000 7,52E-03 0,04208446 ! axonal fasciculation GO:0007413 10 6 0,000 7,52E-03 0,04198544 ! regulation of muscle cell apoptosis GO:0010660 9 6 0,000 7,52E-03 0,04188688 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 7,52E-03 0,04178879 GO:0015991|ATP hydrolysis coupled proton transport, ! midbrain development GO:0030901 7 6 0,000 7,52E-03 0,04169115 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 7,52E-03 0,04159397 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 7,52E-03 0,04149724 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 7 6 0,000 7,52E-03 0,04140096 ! progesterone metabolic process GO:0042448 8 6 0,000 7,52E-03 0,04130512 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 7,52E-03 0,04120973 ! glycolipid catabolic process GO:0019377 14 6 0,000 7,52E-03 0,04111477 GO:0046479|glycosphingolipid catabolic process, ! nonprotein amino acid metabolic process GO:0019794 10 6 0,000 7,52E-03 0,04102026 ! negative regulation of axon extension GO:0030517 13 6 0,000 7,52E-03 0,04092617 ! removal of superoxide radicals GO:0019430 10 6 0,000 7,52E-03 0,04083252 ! triglyceride catabolic process GO:0019433 8 6 0,000 7,52E-03 0,0407393 ! protein modification by small protein removal GO:0070646 10 6 0,000 7,52E-03 0,0406465 GO:0016579|protein deubiquitination, ! adult feeding behavior GO:0008343 6 6 0,000 7,52E-03 0,04055412 ! regulation of Rac protein signal transduction GO:0035020 9 6 0,000 7,52E-03 0,04046216 ! glial cell migration GO:0008347 11 6 0,000 7,52E-03 0,04037062 ! blastocyst growth GO:0001832 17 6 0,000 7,52E-03 0,04027949 ! pigment granule transport GO:0051904 12 6 0,000 7,52E-03 0,04018877 ! lymphocyte activation during immune response GO:0002285 10 6 0,000 7,52E-03 0,04009845 ! cerebellar cortex formation GO:0021697 9 6 0,000 7,52E-03 0,04000855 ! catecholamine transport GO:0051937 7 6 0,000 7,52E-03 0,03991904 ! hemopoietic progenitor cell differentiation GO:0002244 14 6 0,000 7,52E-03 0,03982994 ! positive regulation of actin filament bundle formation GO:0032233 16 6 0,000 7,52E-03 0,03974123 ! organ or tissue specific immune response GO:0002251 7 6 0,000 7,52E-03 0,03965292 ! positive regulation of smooth muscle contraction GO:0045987 10 6 0,000 7,52E-03 0,03956499 ! spindle assembly GO:0051225 6 6 0,000 7,52E-03 0,03947746 ! ensheathment of axons in the peripheral nervous system GO:0032292 15 6 0,000 7,52E-03 0,03939031 GO:0022011|myelination in the peripheral nervous system, ! protein prenylation GO:0018342 10 6 0,000 7,52E-03 0,03930355 ! negative regulation of synaptic transmission GO:0050805 12 6 0,000 7,52E-03 0,03921717 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 7,52E-03 0,03913117 ! NAD biosynthetic process GO:0009435 9 6 0,000 7,52E-03 0,03904554 ! positive regulation of coagulation GO:0050820 11 6 0,000 7,52E-03 0,03896029 ! cellular anion homeostasis GO:0030002 9 6 0,000 7,52E-03 0,03887541 GO:0055081|anion homeostasis, ! behavioral response to cocaine GO:0048148 13 7 0,000 8,767E-03 0,04522876 ! autophagic vacuole formation GO:0000045 12 7 0,000 8,767E-03 0,04513065 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 8,767E-03 0,04503296 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 10 7 0,000 8,767E-03 0,0449357 ! chaperone mediated protein folding requiring cofactor GO:0051085 9 7 0,000 8,767E-03 0,04483886 ! prostate gland development GO:0030850 11 7 0,000 8,767E-03 0,04474243 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 8,767E-03 0,04464642 ! regulation of hormone biosynthetic process GO:0046885 12 7 0,000 8,767E-03 0,04455081 ! synaptonemal complex assembly GO:0007130 11 7 0,000 8,767E-03 0,04445562 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 10 7 0,000 8,767E-03 0,04436083 ! male meiosis GO:0007140 10 7 0,000 8,767E-03 0,04426645 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 8,767E-03 0,04417246 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! reproductive behavior GO:0019098 12 7 0,000 8,767E-03 0,04407888 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 8,767E-03 0,04398569 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 8,767E-03 0,04389289 ! oligopeptide transport GO:0006857 11 7 0,000 8,767E-03 0,04380048 ! protein amino acid sulfation GO:0006477 9 7 0,000 8,767E-03 0,04370847 GO:0051923|sulfation, ! N-terminal protein amino acid acetylation GO:0006474 9 7 0,000 8,767E-03 0,04361683 ! establishment of tissue polarity GO:0007164 10 7 0,000 8,767E-03 0,04352559 ! receptor guanylyl cyclase signaling pathway GO:0007168 7 7 0,000 8,767E-03 0,04343472 ! RNA methylation GO:0001510 11 7 0,000 8,767E-03 0,04334423 ! negative regulation of cell-cell adhesion GO:0022408 20 7 0,000 8,767E-03 0,04325412 ! positive regulation of cell-cell adhesion GO:0022409 17 7 0,000 8,767E-03 0,04316438 ! pericardium development GO:0060039 9 7 0,000 8,767E-03 0,04307501 ! macrophage chemotaxis GO:0048246 10 7 0,000 8,767E-03 0,04298601 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 8,767E-03 0,04289738 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 8,767E-03 0,04280911 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 8,767E-03 0,04272121 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 8,767E-03 0,04263367 ! cerebral cortex cell migration GO:0021795 11 7 0,000 8,767E-03 0,04254648 ! opsonization GO:0008228 9 7 0,000 8,767E-03 0,04245965 ! tachykinin receptor signaling pathway GO:0007217 12 7 0,000 8,767E-03 0,04237318 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 8,767E-03 0,04228705 ! regulation of dopamine metabolic process GO:0042053 10 7 0,000 8,767E-03 0,04220128 GO:0042069|regulation of catecholamine metabolic process, ! glucocorticoid metabolic process GO:0008211 8 7 0,000 8,767E-03 0,04211585 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 8,767E-03 0,04203077 ! chemosensory behavior GO:0007635 9 7 0,000 8,767E-03 0,04194603 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 8,767E-03 0,04186163 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 8,767E-03 0,04177757 ! leukocyte degranulation GO:0043299 11 7 0,000 8,767E-03 0,04169385 ! positive regulation of glycolysis GO:0045821 13 7 0,000 8,767E-03 0,04161046 ! DNA ligation during DNA repair GO:0051103 10 7 0,000 8,767E-03 0,0415274 ! positive regulation of heart rate GO:0010460 11 7 0,000 8,767E-03 0,04144468 ! protein-cofactor linkage GO:0018065 13 7 0,000 8,767E-03 0,04136229 ! lipopolysaccharide metabolic process GO:0008653 7 7 0,000 8,767E-03 0,04128022 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 8,767E-03 0,04119847 ! spinal cord patterning GO:0021511 9 7 0,000 8,767E-03 0,04111705 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 8,767E-03 0,04103596 ! thymic T cell selection GO:0045061 15 7 0,000 8,767E-03 0,04095518 ! regulation of transcriptional preinitiation complex assembly GO:0045898 11 7 0,000 8,767E-03 0,04087471 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 8,767E-03 0,04079457 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 8,767E-03 0,04071474 ! ovulation GO:0030728 8 7 0,000 8,767E-03 0,04063521 ! regulation of isotype switching to IgG isotypes GO:0048302 11 7 0,000 8,767E-03 0,040556 ! histidine metabolic process GO:0006547 7 7 0,000 8,767E-03 0,0404771 GO:0009075|histidine family amino acid metabolic process, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 7 0,000 8,767E-03 0,0403985 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 8,767E-03 0,04032021 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! deoxyribonucleotide biosynthetic process GO:0009263 9 7 0,000 8,767E-03 0,04024222 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 8,767E-03 0,04016454 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! ER overload response GO:0006983 8 7 0,000 8,767E-03 0,04008715 ! thyroid hormone generation GO:0006590 11 7 0,000 8,767E-03 0,04001006 ! endosome organization GO:0007032 10 7 0,000 8,767E-03 0,03993326 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 8,767E-03 0,03985676 GO:0021940|positive regulation of granule cell precursor proliferation, ! positive regulation of interleukin-8 biosynthetic process GO:0045416 8 7 0,000 8,767E-03 0,03978055 ! phasic smooth muscle contraction GO:0014821 13 7 0,000 8,767E-03 0,03970464 ! urea metabolic process GO:0019627 9 7 0,000 8,767E-03 0,03962901 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 14 7 0,000 8,767E-03 0,03955367 ! vesicle fusion GO:0006906 15 7 0,000 8,767E-03 0,03947861 ! positive regulation of insulin secretion GO:0032024 9 7 0,000 8,767E-03 0,03940384 ! maintenance of protein location in nucleus GO:0051457 17 7 0,000 8,767E-03 0,03932936 ! intracellular pH reduction GO:0051452 11 7 0,000 8,767E-03 0,03925515 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 10 7 0,000 8,767E-03 0,03918122 GO:0046464|acylglycerol catabolic process, ! asymmetric protein localization GO:0008105 10 7 0,000 8,767E-03 0,03910757 ! organ growth GO:0035265 13 7 0,000 8,767E-03 0,0390342 ! positive regulation of mesenchymal cell proliferation GO:0002053 10 7 0,000 8,767E-03 0,0389611 ! Rac protein signal transduction GO:0016601 7 7 0,000 8,767E-03 0,03888828 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 7 0,000 8,767E-03 0,03881573 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 8 7 0,000 8,767E-03 0,03874344 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! retinol metabolic process GO:0042572 9 7 0,000 8,767E-03 0,03867143 ! positive regulation of mitotic cell cycle GO:0045931 13 7 0,000 8,767E-03 0,03859968 ! rRNA modification GO:0000154 12 7 0,000 8,767E-03 0,0385282 ! negative regulation of translational initiation GO:0045947 9 7 0,000 8,767E-03 0,03845699 ! DNA damage response, signal transduction resulting in transcription GO:0042772 14 7 0,000 8,767E-03 0,03838603 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 20 7 0,000 8,767E-03 0,03831534 ! protein heterooligomerization GO:0051291 10 7 0,000 8,767E-03 0,03824491 ! response to UV-B GO:0010224 11 7 0,000 8,767E-03 0,03817473 ! astrocyte development GO:0014002 15 7 0,000 8,767E-03 0,03810482 ! intermediate filament organization GO:0045109 12 7 0,000 8,767E-03 0,03803516 ! cardiac muscle cell development GO:0055013 9 7 0,000 8,767E-03 0,03796575 ! fibrinolysis GO:0042730 9 7 0,000 8,767E-03 0,03789659 ! peptidyl-arginine modification GO:0018195 9 7 0,000 8,767E-03 0,03782769 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 7 0,000 8,767E-03 0,03775904 ! blastoderm segmentation GO:0007350 11 7 0,000 8,767E-03 0,03769063 ! skeletal muscle contraction GO:0003009 8 7 0,000 8,767E-03 0,03762248 ! B cell lineage commitment GO:0002326 17 7 0,000 8,767E-03 0,03755457 ! DNA topological change GO:0006265 10 7 0,000 8,767E-03 0,0374869 ! regulation of fat cell differentiation GO:0045598 10 7 0,000 8,767E-03 0,03741948 ! melanosome localization GO:0032400 10 7 0,000 8,767E-03 0,0373523 ! enucleate erythrocyte differentiation GO:0043353 10 7 0,000 8,767E-03 0,03728536 ! regulation of interleukin-5 production GO:0032674 10 7 0,000 8,767E-03 0,03721866 ! glycosylceramide metabolic process GO:0006677 10 7 0,000 8,767E-03 0,0371522 ! mast cell activation GO:0045576 10 7 0,000 8,767E-03 0,03708597 ! multicellular organismal aging GO:0010259 11 7 0,000 8,767E-03 0,03701998 ! negative regulation of focal adhesion formation GO:0051895 16 7 0,000 8,767E-03 0,03695423 ! gas homeostasis GO:0033483 12 7 0,000 8,767E-03 0,03688871 ! negative regulation of T cell differentiation GO:0045581 9 7 0,000 8,767E-03 0,03682342 ! phosphatidylinositol biosynthetic process GO:0006661 11 7 0,000 8,767E-03 0,03675836 ! Schwann cell development GO:0014044 16 7 0,000 8,767E-03 0,03669353 ! dendrite morphogenesis GO:0048813 12 7 0,000 8,767E-03 0,03662893 ! regulation of interleukin-13 production GO:0032656 12 7 0,000 8,767E-03 0,03656455 ! positive regulation of interleukin-4 production GO:0032753 10 7 0,000 8,767E-03 0,0365004 ! molybdopterin cofactor biosynthetic process GO:0032324 10 7 0,000 8,767E-03 0,03643648 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 11 7 0,000 8,767E-03 0,03637278 ! neural tube patterning GO:0021532 8 7 0,000 8,767E-03 0,0363093 ! histone ubiquitination GO:0016574 10 7 0,000 8,767E-03 0,03624604 ! regulation of meiosis GO:0040020 12 7 0,000 8,767E-03 0,03618301 GO:0051445|regulation of meiotic cell cycle, ! eye photoreceptor cell differentiation GO:0001754 14 7 0,000 8,767E-03 0,03612019 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 12 7 0,000 8,767E-03 0,03605759 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 8,767E-03 0,03599521 GO:0002714|positive regulation of B cell mediated immunity, ! mitochondrion morphogenesis GO:0070584 12 7 0,000 8,767E-03 0,03593304 ! regulation of lipid transport GO:0032368 13 7 0,000 8,767E-03 0,03587109 ! regulation of cell division GO:0051302 9 7 0,000 8,767E-03 0,03580935 ! regulation of inflammatory response to antigenic stimulus GO:0002861 14 7 0,000 8,767E-03 0,03574782 ! neutrophil homeostasis GO:0001780 8 7 0,000 8,767E-03 0,0356865 ! regulation of macrophage activation GO:0043030 12 7 0,000 8,767E-03 0,03562539 ! negative regulation of nuclear division GO:0051784 18 7 0,000 8,767E-03 0,0355645 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 8,767E-03 0,03550381 ! diuresis GO:0030146 11 7 0,000 8,767E-03 0,03544332 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 9 7 0,000 8,767E-03 0,03538304 ! positive regulation of epidermis development GO:0045684 11 7 0,000 8,767E-03 0,03532297 ! thiamin metabolic process GO:0006772 8 7 0,000 8,767E-03 0,0352631 ! positive regulation of leukocyte chemotaxis GO:0002690 15 7 0,000 8,767E-03 0,03520343 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of epidermal cell differentiation GO:0045604 10 7 0,000 8,767E-03 0,03514397 ! negative regulation of transmission of nerve impulse GO:0051970 13 7 0,000 8,767E-03 0,0350847 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 8,767E-03 0,03502564 ! dopamine biosynthetic process GO:0042416 15 7 0,000 8,767E-03 0,03496677 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 8,767E-03 0,0349081 ! lymph node development GO:0048535 9 7 0,000 8,767E-03 0,03484963 ! anterior/posterior axis specification GO:0009948 11 7 0,000 8,767E-03 0,03479135 ! negative regulation of viral reproduction GO:0048525 9 7 0,000 8,767E-03 0,03473327 ! regulation of T cell mediated cytotoxicity GO:0001914 15 7 0,000 8,767E-03 0,03467538 ! positive regulation of glucose import GO:0046326 7 7 0,000 8,767E-03 0,03461769 GO:0010828|positive regulation of glucose transport, ! endosome to lysosome transport GO:0008333 11 7 0,000 8,767E-03 0,03456018 ! ATP catabolic process GO:0006200 10 7 0,000 8,767E-03 0,03450287 ! establishment of pigment granule localization GO:0051905 13 7 0,000 8,767E-03 0,03444574 ! positive regulation of fibrinolysis GO:0051919 8 7 0,000 8,767E-03 0,03438881 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 8,767E-03 0,03433206 ! negative regulation of calcium ion transport GO:0051926 8 7 0,000 8,767E-03 0,0342755 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 8,767E-03 0,03421913 ! positive regulation of blood vessel endothelial cell migration GO:0043536 17 7 0,000 8,767E-03 0,03416294 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 8,767E-03 0,03410693 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 8,767E-03 0,03405111 ! muscle adaptation GO:0043500 12 7 0,000 8,767E-03 0,03399547 ! amino sugar catabolic process GO:0046348 9 7 0,000 8,767E-03 0,03394002 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 8 7 0,000 8,767E-03 0,03388474 ! retina homeostasis GO:0001895 9 7 0,000 8,767E-03 0,03382964 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 8,767E-03 0,03377472 ! regulation of growth hormone secretion GO:0060123 14 7 0,000 8,767E-03 0,03371998 ! regulation of T cell receptor signaling pathway GO:0050856 12 7 0,000 8,767E-03 0,03366542 ! positive regulation of microtubule polymerization GO:0031116 12 7 0,000 8,767E-03 0,03361103 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 8,767E-03 0,03355682 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 8 0,000 0,01001394 0,03826582 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 16 8 0,000 0,01001394 0,0382043 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01001394 0,03814297 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01001394 0,03808185 ! oligosaccharide biosynthetic process GO:0009312 14 8 0,000 0,01001394 0,03802092 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 8 0,000 0,01001394 0,03796018 ! negative regulation of cellular catabolic process GO:0031330 10 8 0,000 0,01001394 0,03789964 ! positive regulation of small GTPase mediated signal transduction GO:0051057 16 8 0,000 0,01001394 0,03783929 GO:0046579|positive regulation of Ras protein signal transduction, ! generation of neurons in the forebrain GO:0021872 11 8 0,000 0,01001394 0,03777913 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01001394 0,03771916 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01001394 0,03765939 ! neutral lipid catabolic process GO:0046461 11 8 0,000 0,01001394 0,0375998 ! N-glycan processing GO:0006491 12 8 0,000 0,01001394 0,0375404 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01001394 0,03748119 ! glycosaminoglycan catabolic process GO:0006027 11 8 0,000 0,01001394 0,03742216 ! mRNA stabilization GO:0048255 16 8 0,000 0,01001394 0,03736332 GO:0043489|RNA stabilization, ! induction of positive chemotaxis GO:0050930 16 8 0,000 0,01001394 0,03730467 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01001394 0,0372462 ! lipoprotein transport GO:0042953 14 8 0,000 0,01001394 0,03718791 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01001394 0,0371298 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01001394 0,03707188 ! keratinocyte proliferation GO:0043616 15 8 0,000 0,01001394 0,03701413 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01001394 0,03695657 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01001394 0,03689918 ! amyloid precursor protein catabolic process GO:0042987 13 8 0,000 0,01001394 0,03684197 ! bile acid and bile salt transport GO:0015721 12 8 0,000 0,01001394 0,03678494 ! ganglioside metabolic process GO:0001573 16 8 0,000 0,01001394 0,03672809 ! regulation of mesenchymal cell proliferation GO:0010464 12 8 0,000 0,01001394 0,03667141 ! reflex GO:0060004 16 8 0,000 0,01001394 0,0366149 ! positive regulation of isotype switching GO:0045830 16 8 0,000 0,01001394 0,03655857 GO:0045911|positive regulation of DNA recombination, ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01001394 0,03650242 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of interleukin-12 biosynthetic process GO:0045075 10 8 0,000 0,01001394 0,03644643 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01001394 0,03639062 ! glycerolipid catabolic process GO:0046503 11 8 0,000 0,01001394 0,03633497 ! positive regulation of chemokine biosynthetic process GO:0045080 9 8 0,000 0,01001394 0,0362795 ! hemoglobin metabolic process GO:0020027 12 8 0,000 0,01001394 0,0362242 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01001394 0,03616906 ! nerve growth factor receptor signaling pathway GO:0048011 12 8 0,000 0,01001394 0,03611409 ! insulin-like growth factor receptor signaling pathway GO:0048009 16 8 0,000 0,01001394 0,03605929 ! adrenal gland development GO:0030325 18 8 0,000 0,01001394 0,03600466 ! embryonic cranial skeleton morphogenesis GO:0048701 12 8 0,000 0,01001394 0,03595019 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01001394 0,03589588 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01001394 0,03584174 ! proline metabolic process GO:0006560 9 8 0,000 0,01001394 0,03578776 ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01001394 0,03573394 ! regulation of interleukin-8 biosynthetic process GO:0045414 10 8 0,000 0,01001394 0,03568029 ! regulation of pigmentation during development GO:0048070 18 8 0,000 0,01001394 0,0356268 ! central nervous system neuron axonogenesis GO:0021955 16 8 0,000 0,01001394 0,03557346 GO:0021952|central nervous system projection neuron axonogenesis, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 15 8 0,000 0,01001394 0,03552029 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01001394 0,03546727 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01001394 0,03541441 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of activated T cell proliferation GO:0042104 19 8 0,000 0,01001394 0,03536171 ! galactose metabolic process GO:0006012 14 8 0,000 0,01001394 0,03530917 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01001394 0,03525678 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01001394 0,03520455 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01001394 0,03515247 ! neurotransmitter catabolic process GO:0042135 16 8 0,000 0,01001394 0,03510055 ! ruffle organization GO:0031529 12 8 0,000 0,01001394 0,03504878 ! osteoblast development GO:0002076 14 8 0,000 0,01001394 0,03499716 ! macroautophagy GO:0016236 14 8 0,000 0,01001394 0,03494569 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01001394 0,03489438 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01001394 0,03484321 ! regulation of Notch signaling pathway GO:0008593 22 8 0,000 0,01001394 0,0347922 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01001394 0,03474133 GO:0030204|chondroitin sulfate metabolic process, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 14 8 0,000 0,01001394 0,03469062 ! G1 DNA damage checkpoint GO:0031571 19 8 0,000 0,01001394 0,03464005 ! protein retention in ER lumen GO:0006621 16 8 0,000 0,01001394 0,03458963 ! cardiac muscle cell differentiation GO:0055007 12 8 0,000 0,01001394 0,03453935 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 8 0,000 0,01001394 0,03448922 ! regulation of circadian rhythm GO:0042752 13 8 0,000 0,01001394 0,03443924 ! pigment granule localization GO:0051875 14 8 0,000 0,01001394 0,0343894 ! positive regulation of cytokine production during immune response GO:0002720 12 8 0,000 0,01001394 0,0343397 ! antigen processing and presentation of endogenous antigen GO:0019883 14 8 0,000 0,01001394 0,03429015 ! response to tropane GO:0014073 14 8 0,000 0,01001394 0,03424074 GO:0042220|response to cocaine, ! positive regulation of systemic arterial blood pressure GO:0003084 12 8 0,000 0,01001394 0,03419147 ! embryonic axis specification GO:0000578 12 8 0,000 0,01001394 0,03414235 ! negative regulation of interferon-gamma production GO:0032689 12 8 0,000 0,01001394 0,03409336 ! negative regulation of systemic arterial blood pressure GO:0003085 18 8 0,000 0,01001394 0,03404452 ! sphingomyelin metabolic process GO:0006684 11 8 0,000 0,01001394 0,03399581 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01001394 0,03394725 GO:0016180|snRNA processing, ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 0,01001394 0,03389882 ! regulation of focal adhesion formation GO:0051893 17 8 0,000 0,01001394 0,03385053 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01001394 0,03380238 ! regulation of mitochondrial membrane potential GO:0051881 14 8 0,000 0,01001394 0,03375436 ! regulation of interleukin-10 production GO:0032653 12 8 0,000 0,01001394 0,03370649 ! positive regulation of monooxygenase activity GO:0032770 12 8 0,000 0,01001394 0,03365874 ! protein import into peroxisome matrix GO:0016558 15 8 0,000 0,01001394 0,03361113 ! establishment of nucleus localization GO:0040023 14 8 0,000 0,01001394 0,03356366 ! icosanoid secretion GO:0032309 12 8 0,000 0,01001394 0,03351632 GO:0050482|arachidonic acid secretion, ! intracellular lipid transport GO:0032365 14 8 0,000 0,01001394 0,03346912 ! regulation of transcription from RNA polymerase III promoter GO:0006359 11 8 0,000 0,01001394 0,03342204 ! negative regulation of oxidoreductase activity GO:0051354 13 8 0,000 0,01001394 0,0333751 ! positive regulation of interleukin-1 beta secretion GO:0050718 10 8 0,000 0,01001394 0,03332829 ! regulation of T-helper 1 type immune response GO:0002825 10 8 0,000 0,01001394 0,03328161 ! S phase GO:0051320 8 8 0,000 0,01001394 0,03323507 GO:0000084|S phase of mitotic cell cycle, ! negative regulation of neuroblast proliferation GO:0007406 25 8 0,000 0,01001394 0,03318865 ! regulation of macrophage differentiation GO:0045649 15 8 0,000 0,01001394 0,03314236 ! negative regulation of osteoclast differentiation GO:0045671 12 8 0,000 0,01001394 0,0330962 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01001394 0,03305017 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 8 0,000 0,01001394 0,03300427 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01001394 0,03295849 ! melanin biosynthetic process GO:0042438 11 8 0,000 0,01001394 0,03291284 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01001394 0,03286732 ! regulation of synaptogenesis GO:0051963 12 8 0,000 0,01001394 0,03282192 ! hormone catabolic process GO:0042447 13 8 0,000 0,01001394 0,03277665 ! nicotinamide nucleotide biosynthetic process GO:0019359 12 8 0,000 0,01001394 0,0327315 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01001394 0,03268648 ! positive regulation of ATPase activity GO:0032781 16 8 0,000 0,01001394 0,03264158 ! trophectodermal cell differentiation GO:0001829 10 8 0,000 0,01001394 0,03259681 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01001394 0,03255215 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01001394 0,03250762 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01001394 0,03246321 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 0,01001394 0,03241893 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01001394 0,03237476 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01001394 0,03233071 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 0,01001394 0,03228678 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 8 0,000 0,01001394 0,03224297 ! negative regulation of B cell activation GO:0050869 17 8 0,000 0,01001394 0,03219929 ! behavioral response to nicotine GO:0035095 13 8 0,000 0,01001394 0,03215571 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01001394 0,03211226 GO:0000076|DNA replication checkpoint, ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 0,01001394 0,03206892 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 16 8 0,000 0,01001394 0,0320257 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 14 8 0,000 0,01001394 0,0319826 ! regulation of microtubule polymerization GO:0031113 14 8 0,000 0,01001394 0,03193961 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01125889 0,03586221 ! regulation of developmental growth GO:0048638 14 9 0,000 0,01125889 0,03581413 ! negative regulation of smooth muscle cell proliferation GO:0048662 15 9 0,000 0,01125889 0,03576619 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01125889 0,03571837 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 9 0,000 0,01125889 0,03567069 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 11 9 0,000 0,01125889 0,03562313 ! negative regulation of lipid biosynthetic process GO:0051055 13 9 0,000 0,01125889 0,03557569 ! glycerol-3-phosphate metabolic process GO:0006072 11 9 0,000 0,01125889 0,03552838 ! regulation of cellular amine metabolic process GO:0033238 12 9 0,000 0,01125889 0,0354812 ! cell volume homeostasis GO:0006884 14 9 0,000 0,01125889 0,03543414 ! regulation of epidermal growth factor receptor activity GO:0007176 14 9 0,000 0,01125889 0,03538721 GO:0010469|regulation of receptor activity, ! regulation of smooth muscle cell migration GO:0014910 22 9 0,000 0,01125889 0,0353404 ! UTP metabolic process GO:0046051 10 9 0,000 0,01125889 0,03529372 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! prostaglandin biosynthetic process GO:0001516 15 9 0,000 0,01125889 0,03524716 GO:0046457|prostanoid biosynthetic process, ! succinate metabolic process GO:0006105 16 9 0,000 0,01125889 0,03520072 ! smoothened signaling pathway GO:0007224 10 9 0,000 0,01125889 0,0351544 ! protein complex disassembly GO:0043241 17 9 0,000 0,01125889 0,03510821 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01125889 0,03506213 ! estrogen metabolic process GO:0008210 16 9 0,000 0,01125889 0,03501618 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01125889 0,03497035 ! photoreceptor cell development GO:0042461 17 9 0,000 0,01125889 0,03492463 GO:0046530|photoreceptor cell differentiation, ! cytoplasmic sequestering of transcription factor GO:0042994 12 9 0,000 0,01125889 0,03487904 ! negative regulation of muscle cell differentiation GO:0051148 10 9 0,000 0,01125889 0,03483356 ! microtubule bundle formation GO:0001578 14 9 0,000 0,01125889 0,03478821 ! T-helper 1 type immune response GO:0042088 13 9 0,000 0,01125889 0,03474297 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 22 9 0,000 0,01125889 0,03469785 ! lung alveolus development GO:0048286 18 9 0,000 0,01125889 0,03465285 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01125889 0,03460796 ! pseudouridine synthesis GO:0001522 10 9 0,000 0,01125889 0,03456319 ! endothelial cell differentiation GO:0045446 17 9 0,000 0,01125889 0,03451853 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01125889 0,03447399 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01125889 0,03442957 ! endoderm development GO:0007492 12 9 0,000 0,01125889 0,03438526 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01125889 0,03434106 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01125889 0,03429698 ! myeloid leukocyte mediated immunity GO:0002444 12 9 0,000 0,01125889 0,03425301 ! astrocyte differentiation GO:0048708 17 9 0,000 0,01125889 0,03420915 ! L-phenylalanine metabolic process GO:0006558 11 9 0,000 0,01125889 0,0341654 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 10 9 0,000 0,01125889 0,03412177 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01125889 0,03407825 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 13 9 0,000 0,01125889 0,03403483 ! reverse cholesterol transport GO:0043691 17 9 0,000 0,01125889 0,03399153 ! indolalkylamine metabolic process GO:0006586 15 9 0,000 0,01125889 0,03394834 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! melanin metabolic process GO:0006582 15 9 0,000 0,01125889 0,03390526 ! embryonic eye morphogenesis GO:0048048 15 9 0,000 0,01125889 0,03386229 ! macrophage activation GO:0042116 14 9 0,000 0,01125889 0,03381942 ! multicellular organism growth GO:0035264 16 9 0,000 0,01125889 0,03377667 ! retrograde transport, endosome to Golgi GO:0042147 14 9 0,000 0,01125889 0,03373402 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 0,01125889 0,03369148 ! neuron apoptosis GO:0051402 12 9 0,000 0,01125889 0,03364905 ! lens development in camera-type eye GO:0002088 11 9 0,000 0,01125889 0,03360672 ! positive regulation of vasodilation GO:0045909 14 9 0,000 0,01125889 0,0335645 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01125889 0,03352239 ! positive regulation of muscle contraction GO:0045933 13 9 0,000 0,01125889 0,03348038 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01125889 0,03343848 ! regulation of smoothened signaling pathway GO:0008589 15 9 0,000 0,01125889 0,03339668 ! Schwann cell differentiation GO:0014037 20 9 0,000 0,01125889 0,03335499 ! acyl-CoA metabolic process GO:0006637 14 9 0,000 0,01125889 0,0333134 ! regulation of gliogenesis GO:0014013 21 9 0,000 0,01125889 0,03327191 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 21 9 0,000 0,01125889 0,03323053 ! oligodendrocyte development GO:0014003 13 9 0,000 0,01125889 0,03318925 ! alpha-beta T cell differentiation GO:0046632 15 9 0,000 0,01125889 0,03314807 ! segment specification GO:0007379 11 9 0,000 0,01125889 0,03310699 ! cellular extravasation GO:0045123 12 9 0,000 0,01125889 0,03306602 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01125889 0,03302515 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 13 9 0,000 0,01125889 0,03298438 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01125889 0,0329437 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01125889 0,03290313 ! antigen processing and presentation of exogenous antigen GO:0019884 11 9 0,000 0,01125889 0,03286266 ! positive regulation of production of molecular mediator of immune response GO:0002702 13 9 0,000 0,01125889 0,03282229 ! purine nucleoside triphosphate catabolic process GO:0009146 13 9 0,000 0,01125889 0,03278202 ! regulation of T cell differentiation in the thymus GO:0033081 14 9 0,000 0,01125889 0,03274184 ! response to amine stimulus GO:0014075 13 9 0,000 0,01125889 0,03270177 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of protein kinase B signaling cascade GO:0051896 16 9 0,000 0,01125889 0,03266179 ! erythrocyte development GO:0048821 13 9 0,000 0,01125889 0,03262191 ! renal water homeostasis GO:0003091 13 9 0,000 0,01125889 0,03258213 ! positive regulation of tumor necrosis factor production GO:0032760 10 9 0,000 0,01125889 0,03254244 ! nucleosome disassembly GO:0006337 13 9 0,000 0,01125889 0,03250285 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! spinal cord motor neuron differentiation GO:0021522 12 9 0,000 0,01125889 0,03246336 ! transcription from RNA polymerase I promoter GO:0006360 14 9 0,000 0,01125889 0,03242396 ! induction of an organ GO:0001759 13 9 0,000 0,01125889 0,03238466 ! leukocyte activation during immune response GO:0002366 15 9 0,000 0,01125889 0,03234545 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 11 9 0,000 0,01125889 0,03230634 ! cerebellum morphogenesis GO:0021587 13 9 0,000 0,01125889 0,03226732 GO:0021696|cerebellar cortex morphogenesis, ! retinal ganglion cell axon guidance GO:0031290 11 9 0,000 0,01125889 0,0322284 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01125889 0,03218957 ! sterol catabolic process GO:0016127 11 9 0,000 0,01125889 0,03215084 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 18 9 0,000 0,01125889 0,03211219 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01125889 0,03207364 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 14 9 0,000 0,01125889 0,03203518 ! positive regulation of interleukin-1 secretion GO:0050716 11 9 0,000 0,01125889 0,03199682 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 0,01125889 0,03195855 ! negative regulation of cytokine secretion GO:0050710 13 9 0,000 0,01125889 0,03192036 ! prophase GO:0051324 12 9 0,000 0,01125889 0,03188227 ! neuroblast proliferation GO:0007405 19 9 0,000 0,01125889 0,03184427 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 16 9 0,000 0,01125889 0,03180636 ! peptidyl-threonine modification GO:0018210 22 9 0,000 0,01125889 0,03176854 ! regulation of interleukin-1 beta secretion GO:0050706 12 9 0,000 0,01125889 0,03173081 ! ubiquinone metabolic process GO:0006743 11 9 0,000 0,01125889 0,03169317 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of erythrocyte differentiation GO:0045648 20 9 0,000 0,01125889 0,03165562 ! acid secretion GO:0046717 14 9 0,000 0,01125889 0,03161816 ! purine base metabolic process GO:0006144 18 9 0,000 0,01125889 0,03158079 ! detection of calcium ion GO:0005513 13 9 0,000 0,01125889 0,0315435 ! myeloid cell homeostasis GO:0002262 10 9 0,000 0,01125889 0,0315063 ! regulation of fibrinolysis GO:0051917 14 9 0,000 0,01125889 0,03146919 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01125889 0,03143217 ! natural killer cell mediated immunity GO:0002228 14 9 0,000 0,01125889 0,03139523 GO:0042267|natural killer cell mediated cytotoxicity, ! negative regulation of blood vessel endothelial cell migration GO:0043537 18 9 0,000 0,01125889 0,03135839 ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01125889 0,03132162 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01125889 0,03128495 ! defense response to Gram-positive bacterium GO:0050830 11 9 0,000 0,01125889 0,03124836 ! prepulse inhibition GO:0060134 14 9 0,000 0,01125889 0,03121185 ! sequestering of metal ion GO:0051238 12 9 0,000 0,01125889 0,03117543 ! lamellipodium assembly GO:0030032 12 9 0,000 0,01125889 0,0311391 ! regulation of embryonic development GO:0045995 17 9 0,000 0,01125889 0,03110285 ! mitochondrion localization GO:0051646 15 9 0,000 0,01125889 0,03106668 ! localization within membrane GO:0051668 15 9 0,000 0,01125889 0,0310306 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01250234 0,03441769 ! axon extension GO:0048675 13 10 0,000 0,01250234 0,03437781 ! neuron fate specification GO:0048665 12 10 0,000 0,01250234 0,03433802 ! regulation of epithelial cell differentiation GO:0030856 20 10 0,000 0,01250234 0,03429832 ! cortical actin cytoskeleton organization GO:0030866 24 10 0,000 0,01250234 0,03425872 ! associative learning GO:0008306 19 10 0,000 0,01250234 0,0342192 ! positive regulation of B cell proliferation GO:0030890 14 10 0,000 0,01250234 0,03417978 ! cellular copper ion homeostasis GO:0006878 14 10 0,000 0,01250234 0,03414045 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01250234 0,03410121 ! CTP metabolic process GO:0046036 11 10 0,000 0,01250234 0,03406205 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 17 10 0,000 0,01250234 0,03402299 ! GTP metabolic process GO:0046039 11 10 0,000 0,01250234 0,03398402 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01250234 0,03394514 GO:0007520|myoblast fusion, ! actin-myosin filament sliding GO:0033275 14 10 0,000 0,01250234 0,03390634 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01250234 0,03386764 ! social behavior GO:0035176 15 10 0,000 0,01250234 0,03382902 ! sulfate transport GO:0008272 12 10 0,000 0,01250234 0,03379049 ! regulation of activated T cell proliferation GO:0046006 22 10 0,000 0,01250234 0,03375205 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 19 10 0,000 0,01250234 0,03371369 ! artery development GO:0060840 20 10 0,000 0,01250234 0,03367542 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 13 10 0,000 0,01250234 0,03363724 ! response to pain GO:0048265 20 10 0,000 0,01250234 0,03359915 ! COPI coating of Golgi vesicle GO:0048205 15 10 0,000 0,01250234 0,03356114 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,01250234 0,03352322 ! phospholipid efflux GO:0033700 17 10 0,000 0,01250234 0,03348538 ! hippocampus development GO:0021766 19 10 0,000 0,01250234 0,03344763 ! positive regulation of transcription factor import into nucleus GO:0042993 21 10 0,000 0,01250234 0,03340997 ! amyloid precursor protein metabolic process GO:0042982 16 10 0,000 0,01250234 0,03337238 ! blood vessel remodeling GO:0001974 23 10 0,000 0,01250234 0,03333489 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01250234 0,03329747 ! pathogenesis GO:0009405 13 10 0,000 0,01250234 0,03326014 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01250234 0,0332229 ! two-component signal transduction system (phosphorelay) GO:0000160 15 10 0,000 0,01250234 0,03318574 ! negative regulation of striated muscle development GO:0045843 13 10 0,000 0,01250234 0,03314866 ! protein targeting to ER GO:0045047 21 10 0,000 0,01250234 0,03311166 ! regulation of S phase of mitotic cell cycle GO:0007090 19 10 0,000 0,01250234 0,03307475 ! arginine catabolic process GO:0006527 12 10 0,000 0,01250234 0,03303792 ! melanocyte differentiation GO:0030318 16 10 0,000 0,01250234 0,03300117 GO:0050931|pigment cell differentiation, ! telomere maintenance via telomerase GO:0007004 14 10 0,000 0,01250234 0,0329645 GO:0010833|telomere maintenance via telomere lengthening, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01250234 0,03292791 ! regulation of phosphoprotein phosphatase activity GO:0043666 20 10 0,000 0,01250234 0,03289141 ! regulation of stress fiber formation GO:0051492 24 10 0,000 0,01250234 0,03285498 ! positive regulation of endothelial cell migration GO:0010595 20 10 0,000 0,01250234 0,03281864 ! B cell proliferation GO:0042100 16 10 0,000 0,01250234 0,03278237 ! nucleobase biosynthetic process GO:0046112 20 10 0,000 0,01250234 0,03274619 ! mannose metabolic process GO:0006013 11 10 0,000 0,01250234 0,03271009 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01250234 0,03267406 ! forebrain cell migration GO:0021885 17 10 0,000 0,01250234 0,03263812 ! lipid digestion GO:0044241 15 10 0,000 0,01250234 0,03260225 ! substrate-bound cell migration GO:0006929 11 10 0,000 0,01250234 0,03256646 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01250234 0,03253076 ! receptor clustering GO:0043113 18 10 0,000 0,01250234 0,03249513 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01250234 0,03245957 ! UV protection GO:0009650 14 10 0,000 0,01250234 0,0324241 ! entry into host cell GO:0030260 21 10 0,000 0,01250234 0,0323887 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of lipoprotein lipase activity GO:0051004 20 10 0,000 0,01250234 0,03235338 ! behavioral fear response GO:0001662 19 10 0,000 0,01250234 0,03231814 GO:0002209|behavioral defense response, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01250234 0,03228297 ! negative regulation of ossification GO:0030279 21 10 0,000 0,01250234 0,03224788 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 23 10 0,000 0,01250234 0,03221287 ! protein homotetramerization GO:0051289 20 10 0,000 0,01250234 0,03217793 ! positive regulation of peptide secretion GO:0002793 16 10 0,000 0,01250234 0,03214307 ! response to dsRNA GO:0043331 19 10 0,000 0,01250234 0,03210828 ! DNA ligation GO:0006266 16 10 0,000 0,01250234 0,03207357 ! phosphoinositide 3-kinase cascade GO:0014065 26 10 0,000 0,01250234 0,03203893 ! regulation of interleukin-4 production GO:0032673 18 10 0,000 0,01250234 0,03200437 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01250234 0,03196988 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01250234 0,03193547 ! positive regulation of Ras GTPase activity GO:0032320 24 10 0,000 0,01250234 0,03190113 ! postreplication repair GO:0006301 16 10 0,000 0,01250234 0,03186686 ! fucose catabolic process GO:0019317 17 10 0,000 0,01250234 0,03183267 GO:0042355|L-fucose catabolic process, ! mRNA cleavage GO:0006379 14 10 0,000 0,01250234 0,03179855 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01250234 0,03176451 ! hindbrain morphogenesis GO:0021575 16 10 0,000 0,01250234 0,03173053 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 10 0,000 0,01250234 0,03169663 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 13 10 0,000 0,01250234 0,03166281 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01250234 0,03162905 ! positive regulation of neuron differentiation GO:0045666 13 10 0,000 0,01250234 0,03159537 ! positive regulation of leukocyte migration GO:0002687 24 10 0,000 0,01250234 0,03156175 ! multicellular organismal water homeostasis GO:0050891 14 10 0,000 0,01250234 0,03152821 ! negative regulation of lymphocyte differentiation GO:0045620 13 10 0,000 0,01250234 0,03149474 ! methionine biosynthetic process GO:0009086 13 10 0,000 0,01250234 0,03146135 ! oocyte differentiation GO:0009994 14 10 0,000 0,01250234 0,03142802 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 14 10 0,000 0,01250234 0,03139476 ! spleen development GO:0048536 17 10 0,000 0,01250234 0,03136157 ! negative regulation of BMP signaling pathway GO:0030514 15 10 0,000 0,01250234 0,03132846 ! regulation of RNA splicing GO:0043484 15 10 0,000 0,01250234 0,03129541 ! positive regulation of viral reproduction GO:0048524 14 10 0,000 0,01250234 0,03126243 ! blastocyst formation GO:0001825 14 10 0,000 0,01250234 0,03122953 ! embryonic gut development GO:0048566 13 10 0,000 0,01250234 0,03119669 ! quinone cofactor metabolic process GO:0042375 12 10 0,000 0,01250234 0,03116392 ! cerebellar cortex development GO:0021695 14 10 0,000 0,01250234 0,03113122 ! activation of innate immune response GO:0002218 10 10 0,000 0,01250234 0,03109858 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01250234 0,03106602 ! insulin secretion GO:0030073 18 10 0,000 0,01250234 0,03103352 ! cytoplasmic sequestering of protein GO:0051220 15 10 0,000 0,01250234 0,0310011 ! response to nicotine GO:0035094 18 10 0,000 0,01250234 0,03096874 ! establishment of cell polarity GO:0030010 12 10 0,000 0,01250234 0,03093644 ! nucleus localization GO:0051647 16 10 0,000 0,01250234 0,03090422 ! regulation of synapse organization GO:0050807 14 10 0,000 0,01250234 0,03087206 ! negative regulation of muscle development GO:0048635 14 11 0,000 0,01374429 0,03390353 ! positive regulation of glucose metabolic process GO:0010907 17 11 0,000 0,01374429 0,03386832 ! ER-associated protein catabolic process GO:0030433 17 11 0,000 0,01374429 0,03383319 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of blood pressure GO:0045776 25 11 0,000 0,01374429 0,03379813 ! cortical cytoskeleton organization GO:0030865 25 11 0,000 0,01374429 0,03376314 ! virus-host interaction GO:0019048 20 11 0,000 0,01374429 0,03372822 ! thyroid gland development GO:0030878 20 11 0,000 0,01374429 0,03369338 ! pentose-phosphate shunt GO:0006098 14 11 0,000 0,01374429 0,03365861 GO:0006740|NADPH regeneration, ! regulation of phosphatase activity GO:0010921 23 11 0,000 0,01374429 0,03362391 ! non-recombinational repair GO:0000726 19 11 0,000 0,01374429 0,03358928 GO:0006303|double-strand break repair via nonhomologous end joining, ! synapsis GO:0007129 15 11 0,000 0,01374429 0,03355472 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 11 11 0,000 0,01374429 0,03352024 ! Golgi vesicle budding GO:0048194 18 11 0,000 0,01374429 0,03348582 ! elastic fiber assembly GO:0048251 17 11 0,000 0,01374429 0,03345148 ! regulation of positive chemotaxis GO:0050926 19 11 0,000 0,01374429 0,0334172 GO:0050927|positive regulation of positive chemotaxis, ! regulation of glycolysis GO:0006110 18 11 0,000 0,01374429 0,033383 ! dopamine receptor signaling pathway GO:0007212 25 11 0,000 0,01374429 0,03334887 ! regulation of cell projection assembly GO:0060491 22 11 0,000 0,01374429 0,0333148 ! positive regulation of lipid metabolic process GO:0045834 15 11 0,000 0,01374429 0,03328081 ! bone resorption GO:0045453 16 11 0,000 0,01374429 0,03324688 ! regulation of chemokine biosynthetic process GO:0045073 13 11 0,000 0,01374429 0,03321303 ! peptide or protein amino-terminal blocking GO:0018409 16 11 0,000 0,01374429 0,03317924 ! ventral spinal cord development GO:0021517 15 11 0,000 0,01374429 0,03314552 ! regulated secretory pathway GO:0045055 15 11 0,000 0,01374429 0,03311187 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 19 11 0,000 0,01374429 0,03307829 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! regulation of catecholamine secretion GO:0050433 21 11 0,000 0,01374429 0,03304477 ! syncytium formation GO:0006949 15 11 0,000 0,01374429 0,03301133 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01374429 0,03297795 ! glucan biosynthetic process GO:0009250 14 11 0,000 0,01374429 0,03294464 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 16 11 0,000 0,01374429 0,03291139 ! Golgi organization GO:0007030 19 11 0,000 0,01374429 0,03287822 ! response to X-ray GO:0010165 19 11 0,000 0,01374429 0,03284511 ! retinoic acid receptor signaling pathway GO:0048384 16 11 0,000 0,01374429 0,03281206 ! adult heart development GO:0007512 12 11 0,000 0,01374429 0,03277909 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01374429 0,03274618 ! epithelial cell development GO:0002064 16 11 0,000 0,01374429 0,03271333 ! actin cytoskeleton reorganization GO:0031532 20 11 0,000 0,01374429 0,03268055 ! temperature homeostasis GO:0001659 16 11 0,000 0,01374429 0,03264784 ! L-glutamate transport GO:0015813 15 11 0,000 0,01374429 0,03261519 GO:0015800|acidic amino acid transport, ! positive regulation vascular endothelial growth factor production GO:0010575 19 11 0,000 0,01374429 0,03258261 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01374429 0,03255009 ! motor axon guidance GO:0008045 17 11 0,000 0,01374429 0,03251764 ! copper ion homeostasis GO:0055070 15 11 0,000 0,01374429 0,03248525 ! protein targeting to peroxisome GO:0006625 21 11 0,000 0,01374429 0,03245293 ! regulation of bone resorption GO:0045124 27 11 0,000 0,01374429 0,03242067 ! stem cell development GO:0048864 30 11 0,000 0,01374429 0,03238847 GO:0019827|stem cell maintenance, ! alpha-beta T cell activation GO:0046631 18 11 0,000 0,01374429 0,03235634 ! negative regulation of axonogenesis GO:0050771 26 11 0,000 0,01374429 0,03232427 ! regulation of phagocytosis GO:0050764 16 11 0,000 0,01374429 0,03229227 ! regulation of insulin receptor signaling pathway GO:0046626 17 11 0,000 0,01374429 0,03226033 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01374429 0,03222845 ! nucleoside triphosphate catabolic process GO:0009143 16 11 0,000 0,01374429 0,03219664 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01374429 0,03216488 ! synaptic vesicle exocytosis GO:0016079 16 11 0,000 0,01374429 0,03213319 ! regulation of B cell differentiation GO:0045577 23 11 0,000 0,01374429 0,03210157 ! cranial nerve development GO:0021545 14 11 0,000 0,01374429 0,03207 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01374429 0,0320385 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01374429 0,03200706 ! salivary gland development GO:0007431 24 11 0,000 0,01374429 0,03197568 ! negative regulation of neurological system process GO:0031645 20 11 0,000 0,01374429 0,03194436 ! regulation of leukocyte migration GO:0002685 25 11 0,000 0,01374429 0,0319131 ! musculoskeletal movement GO:0050881 16 11 0,000 0,01374429 0,03188191 GO:0050879|multicellular organismal movement, ! nitric oxide mediated signal transduction GO:0007263 20 11 0,000 0,01374429 0,03185077 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01374429 0,0318197 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01374429 0,03178869 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 20 11 0,000 0,01374429 0,03175773 ! digestive tract morphogenesis GO:0048546 16 11 0,000 0,01374429 0,03172684 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 11 0,000 0,01374429 0,03169601 ! thyroid hormone metabolic process GO:0042403 17 11 0,000 0,01374429 0,03166523 ! leukocyte mediated cytotoxicity GO:0001909 18 11 0,000 0,01374429 0,03163452 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01374429 0,03160387 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 21 11 0,000 0,01374429 0,03157327 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01374429 0,03154274 ! regulation of actin filament bundle formation GO:0032231 25 11 0,000 0,01374429 0,03151226 ! cardiac cell differentiation GO:0035051 18 11 0,000 0,01374429 0,03148185 ! defense response to fungus GO:0050832 13 11 0,000 0,01374429 0,03145149 ! lysogeny GO:0030069 20 11 0,000 0,01374429 0,03142119 GO:0019047|provirus integration, ! T cell receptor signaling pathway GO:0050852 22 11 0,000 0,01374429 0,03139094 ! acrosome reaction GO:0007340 14 11 0,000 0,01374429 0,03136076 ! regulation of synapse structure and activity GO:0050803 15 11 0,000 0,01374429 0,03133064 ! regulation of steroid biosynthetic process GO:0050810 13 11 0,000 0,01374429 0,03130057 ! rRNA transcription GO:0009303 19 12 0,000 0,01498473 0,03409279 ! reproductive cellular process GO:0048610 15 12 0,000 0,01498473 0,03406013 ! regulation of membrane protein ectodomain proteolysis GO:0051043 17 12 0,000 0,01498473 0,03402754 ! pteridine and derivative biosynthetic process GO:0042559 15 12 0,000 0,01498473 0,03399501 ! dicarboxylic acid transport GO:0006835 21 12 0,000 0,01498473 0,03396254 ! phosphate transport GO:0006817 15 12 0,000 0,01498473 0,03393013 ! positive regulation of GTPase activity GO:0043547 29 12 0,000 0,01498473 0,03389778 ! peroxisomal transport GO:0043574 22 12 0,000 0,01498473 0,0338655 ! mating GO:0007618 16 12 0,000 0,01498473 0,03383328 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01498473 0,03380112 ! heart looping GO:0001947 15 12 0,000 0,01498473 0,03376902 ! negative regulation of cell-matrix adhesion GO:0001953 31 12 0,000 0,01498473 0,03373698 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 20 12 0,000 0,01498473 0,033705 ! negative regulation of proteolysis GO:0045861 17 12 0,000 0,01498473 0,03367308 ! T cell selection GO:0045058 25 12 0,000 0,01498473 0,03364123 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01498473 0,03360943 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 17 12 0,000 0,01498473 0,03357769 ! oligodendrocyte differentiation GO:0048709 19 12 0,000 0,01498473 0,03354601 ! plasma membrane organization GO:0007009 19 12 0,000 0,01498473 0,0335144 ! focal adhesion formation GO:0048041 28 12 0,000 0,01498473 0,03348284 ! mitotic spindle organization GO:0007052 16 12 0,000 0,01498473 0,03345134 ! cellular carbohydrate catabolic process GO:0044275 14 12 0,000 0,01498473 0,0334199 ! regulation of intracellular pH GO:0051453 19 12 0,000 0,01498473 0,03338852 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01498473 0,0333572 ! monoamine transport GO:0015844 14 12 0,000 0,01498473 0,03332594 ! regulation of vascular endothelial growth factor production GO:0010574 20 12 0,000 0,01498473 0,03329473 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 18 12 0,000 0,01498473 0,03326359 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01498473 0,0332325 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01498473 0,03320147 ! regulation of organ growth GO:0046620 14 12 0,000 0,01498473 0,0331705 ! vasoconstriction GO:0042310 18 12 0,000 0,01498473 0,03313959 ! RNA-dependent DNA replication GO:0006278 16 12 0,000 0,01498473 0,03310873 ! regulation of interleukin-8 production GO:0032677 19 12 0,000 0,01498473 0,03307793 ! regulation of Rho GTPase activity GO:0032319 22 12 0,000 0,01498473 0,03304719 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01498473 0,0330165 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01498473 0,03298588 ! histone deacetylation GO:0016575 14 12 0,000 0,01498473 0,03295531 ! histone acetylation GO:0016573 27 12 0,000 0,01498473 0,03292479 ! DNA methylation GO:0006306 19 12 0,000 0,01498473 0,03289433 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 19 12 0,000 0,01498473 0,03286393 ! protein sumoylation GO:0016925 14 12 0,000 0,01498473 0,03283359 ! chromatin silencing GO:0006342 23 12 0,000 0,01498473 0,0328033 ! negative regulation of MAPKKK cascade GO:0043409 23 12 0,000 0,01498473 0,03277307 ! gland morphogenesis GO:0022612 24 12 0,000 0,01498473 0,03274289 ! regulation of hormone metabolic process GO:0032350 21 12 0,000 0,01498473 0,03271277 ! zymogen activation GO:0031638 16 12 0,000 0,01498473 0,0326827 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01498473 0,03265269 ! nucleosome positioning GO:0016584 13 12 0,000 0,01498473 0,03262273 ! regulation of isotype switching GO:0045191 22 12 0,000 0,01498473 0,03259283 ! glutathione biosynthetic process GO:0006750 14 12 0,000 0,01498473 0,03256298 ! response to gamma radiation GO:0010332 21 12 0,000 0,01498473 0,03253319 ! regulation of osteoclast differentiation GO:0045670 18 12 0,000 0,01498473 0,03250345 ! regulation of T-helper 2 cell differentiation GO:0045628 19 12 0,000 0,01498473 0,03247377 ! aromatic amino acid family catabolic process GO:0009074 16 12 0,000 0,01498473 0,03244414 ! serine family amino acid biosynthetic process GO:0009070 16 12 0,000 0,01498473 0,03241456 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01498473 0,03238504 ! male genitalia development GO:0030539 15 12 0,000 0,01498473 0,03235557 ! regulation of cellular carbohydrate catabolic process GO:0043471 19 12 0,000 0,01498473 0,03232616 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of fatty acid oxidation GO:0046320 20 12 0,000 0,01498473 0,0322968 ! establishment or maintenance of apical/basal cell polarity GO:0035088 23 12 0,000 0,01498473 0,03226749 ! developmental induction GO:0031128 16 12 0,000 0,01498473 0,03223824 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 15 12 0,000 0,01498473 0,03220904 ! response to cold GO:0009409 15 12 0,000 0,01498473 0,03217989 ! negative regulation of immune effector process GO:0002698 20 12 0,000 0,01498473 0,03215079 ! respiratory burst GO:0045730 22 13 0,000 0,01622369 0,0347776 ! lactation GO:0007595 22 13 0,000 0,01622369 0,03474621 ! tRNA modification GO:0006400 15 13 0,000 0,01622369 0,03471488 ! negative regulation of cell projection organization GO:0031345 29 13 0,000 0,01622369 0,03468361 ! positive regulation of blood pressure GO:0045777 19 13 0,000 0,01622369 0,03465239 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01622369 0,03462123 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 20 13 0,000 0,01622369 0,03459012 ! water transport GO:0006833 21 13 0,000 0,01622369 0,03455907 GO:0042044|fluid transport, ! regulation of B cell proliferation GO:0030888 24 13 0,000 0,01622369 0,03452808 ! regulation of nitric-oxide synthase activity GO:0050999 23 13 0,000 0,01622369 0,03449714 ! copper ion transport GO:0006825 15 13 0,000 0,01622369 0,03446625 ! filopodium assembly GO:0046847 21 13 0,000 0,01622369 0,03443543 ! lipid localization GO:0010876 25 13 0,000 0,01622369 0,03440465 GO:0019915|lipid storage, ! detection of mechanical stimulus GO:0050982 17 13 0,000 0,01622369 0,03437393 ! negative regulation of transcription factor import into nucleus GO:0042992 26 13 0,000 0,01622369 0,03434327 ! cytokine biosynthetic process GO:0042089 17 13 0,000 0,01622369 0,03431266 ! T cell proliferation GO:0042098 24 13 0,000 0,01622369 0,03428211 ! organelle fusion GO:0048284 29 13 0,000 0,01622369 0,03425161 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01622369 0,03422116 ! endocrine pancreas development GO:0031018 19 13 0,000 0,01622369 0,03419077 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 24 13 0,000 0,01622369 0,03416043 ! platelet-derived growth factor receptor signaling pathway GO:0048008 20 13 0,000 0,01622369 0,03413015 ! photoreceptor cell maintenance GO:0045494 20 13 0,000 0,01622369 0,03409992 ! regulation of mRNA processing GO:0050684 21 13 0,000 0,01622369 0,03406974 ! regulation of skeletal muscle fiber development GO:0048742 22 13 0,000 0,01622369 0,03403962 ! methionine metabolic process GO:0006555 16 13 0,000 0,01622369 0,03400955 ! deoxyribonucleotide catabolic process GO:0009264 17 13 0,000 0,01622369 0,03397953 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01622369 0,03394956 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 21 13 0,000 0,01622369 0,03391965 ! negative regulation of endothelial cell migration GO:0010596 22 13 0,000 0,01622369 0,03388979 ! membrane protein proteolysis GO:0033619 21 13 0,000 0,01622369 0,03385999 GO:0006509|membrane protein ectodomain proteolysis, ! fear response GO:0042596 22 13 0,000 0,01622369 0,03383023 ! neutral amino acid transport GO:0015804 20 13 0,000 0,01622369 0,03380053 ! negative regulation of mitotic cell cycle GO:0045930 32 13 0,000 0,01622369 0,03377088 ! regulation of natural killer cell mediated immunity GO:0002715 21 13 0,000 0,01622369 0,03374128 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 16 13 0,000 0,01622369 0,03371174 ! positive regulation of protein import into nucleus GO:0042307 24 13 0,000 0,01622369 0,03368224 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01622369 0,0336528 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01622369 0,03362341 ! cellular pigmentation GO:0033059 24 13 0,000 0,01622369 0,03359407 ! histone methylation GO:0016571 16 13 0,000 0,01622369 0,03356478 ! regulation of epidermis development GO:0045682 21 13 0,000 0,01622369 0,03353554 ! oxygen transport GO:0015671 20 13 0,000 0,01622369 0,03350636 ! regulation of axon extension GO:0030516 26 13 0,000 0,01622369 0,03347722 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 24 13 0,000 0,01622369 0,03344814 ! detection of bacterium GO:0016045 13 13 0,000 0,01622369 0,0334191 ! L-fucose metabolic process GO:0042354 21 13 0,000 0,01622369 0,03339012 ! regulation of NF-kappaB import into nucleus GO:0042345 24 13 0,000 0,01622369 0,03336118 ! positive regulation of homeostatic process GO:0032846 19 13 0,000 0,01622369 0,0333323 ! positive regulation of protein polymerization GO:0032273 21 13 0,000 0,01622369 0,03330347 ! actin filament polymerization GO:0030041 18 13 0,000 0,01622369 0,03327468 ! regulation of protein ubiquitination GO:0031396 20 14 0,000 0,01746114 0,03578177 ! N-terminal protein amino acid modification GO:0031365 20 14 0,000 0,01746114 0,03575089 ! positive regulation of cellular catabolic process GO:0031331 24 14 0,000 0,01746114 0,03572007 ! G1 phase of mitotic cell cycle GO:0000080 24 14 0,000 0,01746114 0,03568931 ! neuron maturation GO:0042551 24 14 0,000 0,01746114 0,03565859 ! regulation of S phase GO:0033261 25 14 0,000 0,01746114 0,03562793 ! regulation of chemokine production GO:0032642 18 14 0,000 0,01746114 0,03559732 ! myotube differentiation GO:0014902 21 14 0,000 0,01746114 0,03556677 ! double-strand break repair via homologous recombination GO:0000724 24 14 0,000 0,01746114 0,03553627 GO:0000725|recombinational repair, ! negative regulation of bone remodeling GO:0046851 28 14 0,000 0,01746114 0,03550581 ! phospholipid catabolic process GO:0009395 19 14 0,000 0,01746114 0,03547542 ! aminoglycan catabolic process GO:0006026 19 14 0,000 0,01746114 0,03544507 ! vesicle targeting, to, from or within Golgi GO:0048199 19 14 0,000 0,01746114 0,03541477 ! cardiac muscle contraction GO:0060048 28 14 0,000 0,01746114 0,03538453 ! RNA polyadenylation GO:0043631 21 14 0,000 0,01746114 0,03535434 ! cartilage condensation GO:0001502 22 14 0,000 0,01746114 0,0353242 ! gene silencing by RNA GO:0031047 22 14 0,000 0,01746114 0,03529411 ! response to cAMP GO:0051591 20 14 0,000 0,01746114 0,03526407 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 17 14 0,000 0,01746114 0,03523409 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 14 0,000 0,01746114 0,03520415 ! negative regulation of cytokine biosynthetic process GO:0042036 19 14 0,000 0,01746114 0,03517427 ! limbic system development GO:0021761 25 14 0,000 0,01746114 0,03514443 ! positive regulation of ion transport GO:0043270 18 14 0,000 0,01746114 0,03511465 GO:0051928|positive regulation of calcium ion transport, ! startle response GO:0001964 21 14 0,000 0,01746114 0,03508492 ! palate development GO:0060021 19 14 0,000 0,01746114 0,03505523 ! negative regulation of gene expression, epigenetic GO:0045814 30 14 0,000 0,01746114 0,0350256 ! negative regulation of protein amino acid phosphorylation GO:0001933 31 14 0,000 0,01746114 0,03499602 ! regulation of defense response to virus GO:0050688 26 14 0,000 0,01746114 0,03496649 ! response to hexose stimulus GO:0009746 22 14 0,000 0,01746114 0,034937 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! epidermis morphogenesis GO:0048730 31 14 0,000 0,01746114 0,03490757 ! arginine metabolic process GO:0006525 17 14 0,000 0,01746114 0,03487819 ! glutamate metabolic process GO:0006536 21 14 0,000 0,01746114 0,03484885 ! glycine metabolic process GO:0006544 22 14 0,000 0,01746114 0,03481957 ! pituitary gland development GO:0021983 24 14 0,000 0,01746114 0,03479033 ! tyrosine metabolic process GO:0006570 20 14 0,000 0,01746114 0,03476115 ! negative regulation of microtubule depolymerization GO:0007026 34 14 0,000 0,01746114 0,03473201 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 21 14 0,000 0,01746114 0,03470292 ! cytokine metabolic process GO:0042107 18 14 0,000 0,01746114 0,03467388 ! NAD metabolic process GO:0019674 25 14 0,000 0,01746114 0,03464489 ! regulation of ion transmembrane transporter activity GO:0032412 19 14 0,000 0,01746114 0,03461594 ! regulation of heart rate GO:0002027 26 14 0,000 0,01746114 0,03458705 ! exocrine system development GO:0035272 29 14 0,000 0,01746114 0,0345582 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,01746114 0,0345294 ! positive regulation of carbohydrate metabolic process GO:0045913 22 14 0,000 0,01746114 0,03450065 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! purine nucleoside monophosphate metabolic process GO:0009126 22 14 0,000 0,01746114 0,03447195 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 25 14 0,000 0,01746114 0,0344433 ! axon cargo transport GO:0008088 29 14 0,000 0,01746114 0,03441469 ! positive regulation of T cell mediated immunity GO:0002711 30 14 0,000 0,01746114 0,03438613 ! negative regulation of protein import into nucleus GO:0042308 27 14 0,000 0,01746114 0,03435762 ! genitalia development GO:0048806 18 14 0,000 0,01746114 0,03432915 ! regulation of interleukin-12 production GO:0032655 20 14 0,000 0,01746114 0,03430073 ! autonomic nervous system development GO:0048483 26 14 0,000 0,01746114 0,03427236 ! tissue regeneration GO:0042246 24 14 0,000 0,01746114 0,03424404 ! negative regulation of protein secretion GO:0050709 22 14 0,000 0,01746114 0,03421576 ! water homeostasis GO:0030104 23 14 0,000 0,01746114 0,03418753 ! cofactor transport GO:0051181 22 14 0,000 0,01746114 0,03415934 ! regulation of acute inflammatory response GO:0002673 21 14 0,000 0,01746114 0,03413121 ! positive regulation of T-helper cell differentiation GO:0045624 20 14 0,000 0,01746114 0,03410312 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01746114 0,03407507 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01746114 0,03404707 ! regulation of mRNA stability GO:0043488 30 14 0,000 0,01746114 0,03401912 ! cell killing GO:0001906 22 14 0,000 0,01746114 0,03399121 ! positive regulation of JNK cascade GO:0046330 22 14 0,000 0,01746114 0,03396335 ! epithelial to mesenchymal transition GO:0001837 24 14 0,000 0,01746114 0,03393553 ! negative regulation of mast cell proliferation GO:0070667 26 14 0,000 0,01746114 0,03390776 GO:0042130|negative regulation of T cell proliferation, ! mRNA 3'-end processing GO:0031124 21 14 0,000 0,01746114 0,03388004 ! microspike assembly GO:0030035 25 14 0,000 0,01746114 0,03385236 ! positive regulation of calcium-mediated signaling GO:0050850 27 14 0,000 0,01746114 0,03382472 ! regulation of skeletal muscle tissue development GO:0048641 24 15 0,000 0,0186971 0,03618941 ! superoxide anion generation GO:0042554 19 15 0,000 0,0186971 0,03615992 ! negative regulation of hormone secretion GO:0046888 22 15 0,000 0,0186971 0,03613047 ! skin development GO:0043588 28 15 0,000 0,0186971 0,03610107 ! embryonic hindlimb morphogenesis GO:0035116 28 15 0,000 0,0186971 0,03607172 ! embryonic forelimb morphogenesis GO:0035115 18 15 0,000 0,0186971 0,03604242 ! inositol metabolic process GO:0006020 21 15 0,000 0,0186971 0,03601316 ! retina development in camera-type eye GO:0060041 22 15 0,000 0,0186971 0,03598396 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 22 15 0,000 0,0186971 0,0359548 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 25 15 0,000 0,0186971 0,03592568 ! regulation of transmembrane transporter activity GO:0022898 20 15 0,000 0,0186971 0,03589662 GO:0032409|regulation of transporter activity, ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,0186971 0,0358676 ! activation of MAPKK activity GO:0000186 22 15 0,000 0,0186971 0,03583863 ! induction of apoptosis via death domain receptors GO:0008625 19 15 0,000 0,0186971 0,0358097 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 18 15 0,000 0,0186971 0,03578082 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0186971 0,03575199 ! response to osmotic stress GO:0006970 23 15 0,000 0,0186971 0,0357232 ! vesicle coating GO:0006901 26 15 0,000 0,0186971 0,03569446 ! regulation of the force of heart contraction GO:0002026 24 15 0,000 0,0186971 0,03566577 ! preassembly of GPI anchor in ER membrane GO:0016254 22 15 0,000 0,0186971 0,03563712 ! positive regulation of activation of JAK2 kinase activity GO:0010535 15 15 0,000 0,0186971 0,03560852 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 23 15 0,000 0,0186971 0,03557997 ! bone mineralization GO:0030282 17 15 0,000 0,0186971 0,03555146 ! G1/S transition checkpoint GO:0031575 36 15 0,000 0,0186971 0,03552299 ! intermediate filament cytoskeleton organization GO:0045104 27 15 0,000 0,0186971 0,03549457 ! positive regulation of axonogenesis GO:0050772 21 15 0,000 0,0186971 0,0354662 ! regulation of cytokine production during immune response GO:0002718 23 15 0,000 0,0186971 0,03543787 ! T cell differentiation in the thymus GO:0033077 30 15 0,000 0,0186971 0,03540959 ! regulation of cellular pH GO:0030641 23 15 0,000 0,0186971 0,03538135 ! ribosome assembly GO:0042255 17 15 0,000 0,0186971 0,03535316 ! cerebellum development GO:0021549 19 15 0,000 0,0186971 0,03532501 ! regulation of monooxygenase activity GO:0032768 29 15 0,000 0,0186971 0,03529691 ! mRNA splice site selection GO:0006376 33 15 0,000 0,0186971 0,03526885 ! positive regulation of cytokine secretion GO:0050715 19 15 0,000 0,0186971 0,03524084 ! regulation of T-helper 2 type immune response GO:0002828 24 15 0,000 0,0186971 0,03521287 ! negative regulation of inflammatory response GO:0050728 18 15 0,000 0,0186971 0,03518495 ! sphingolipid catabolic process GO:0030149 27 15 0,000 0,0186971 0,03515707 GO:0046466|membrane lipid catabolic process, ! positive regulation of bone mineralization GO:0030501 22 15 0,000 0,0186971 0,03512923 ! regulation of erythrocyte differentiation GO:0045646 29 15 0,000 0,0186971 0,03510144 ! muscle maintenance GO:0046716 21 15 0,000 0,0186971 0,03507369 ! C21-steroid hormone biosynthetic process GO:0006700 17 15 0,000 0,0186971 0,03504599 ! activation of NF-kappaB-inducing kinase activity GO:0007250 23 15 0,000 0,0186971 0,03501833 ! intestinal absorption GO:0050892 22 15 0,000 0,0186971 0,03499071 ! regulation of ATPase activity GO:0043462 24 15 0,000 0,0186971 0,03496314 ! dopamine metabolic process GO:0042417 32 15 0,000 0,0186971 0,03493561 ! gas transport GO:0015669 23 15 0,000 0,0186971 0,03490812 ! regulation of RNA stability GO:0043487 31 15 0,000 0,0186971 0,03488067 ! organic cation transport GO:0015695 19 15 0,000 0,0186971 0,03485327 ! heme biosynthetic process GO:0006783 22 15 0,000 0,0186971 0,03482592 ! regulation of BMP signaling pathway GO:0030510 24 15 0,000 0,0186971 0,0347986 ! aromatic compound biosynthetic process GO:0019438 18 15 0,000 0,0186971 0,03477133 ! release of cytochrome c from mitochondria GO:0001836 29 15 0,000 0,0186971 0,0347441 ! cilium assembly GO:0042384 22 15 0,000 0,0186971 0,03471692 ! regulation of calcium-mediated signaling GO:0050848 28 15 0,000 0,0186971 0,03468977 ! inner ear receptor cell differentiation GO:0060113 30 15 0,000 0,0186971 0,03466267 ! peptide hormone processing GO:0016486 23 15 0,000 0,0186971 0,03463561 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 36 15 0,000 0,0186971 0,03460859 ! sulfur amino acid biosynthetic process GO:0000097 21 16 0,000 0,01993157 0,03686486 ! bone remodeling GO:0046849 24 16 0,000 0,01993157 0,03683614 ! negative regulation of nucleocytoplasmic transport GO:0046823 29 16 0,000 0,01993157 0,03680748 ! positive regulation of nucleocytoplasmic transport GO:0046824 28 16 0,000 0,01993157 0,03677886 ! regulation of cell-cell adhesion GO:0022407 38 16 0,000 0,01993157 0,03675028 ! bile acid metabolic process GO:0008206 23 16 0,000 0,01993157 0,03672175 ! axis specification GO:0009798 26 16 0,000 0,01993157 0,03669326 ! negative regulation of endothelial cell proliferation GO:0001937 33 16 0,000 0,01993157 0,03666481 ! mitotic chromosome condensation GO:0007076 26 16 0,000 0,01993157 0,03663641 ! positive regulation of cell growth GO:0030307 22 16 0,000 0,01993157 0,03660806 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01993157 0,03657974 ! centrosome cycle GO:0007098 18 16 0,000 0,01993157 0,03655148 ! cell differentiation in spinal cord GO:0021515 24 16 0,000 0,01993157 0,03652325 ! regulation of survival gene product expression GO:0045884 23 16 0,000 0,01993157 0,03649507 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 16 0,000 0,01993157 0,03646693 ! cellular response to starvation GO:0009267 26 16 0,000 0,01993157 0,03643884 ! DNA integration GO:0015074 25 16 0,000 0,01993157 0,03641079 ! branching involved in ureteric bud morphogenesis GO:0001658 24 16 0,000 0,01993157 0,03638278 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 35 16 0,000 0,01993157 0,03635481 ! regulation of exocytosis GO:0017157 28 16 0,000 0,01993157 0,03632689 ! embryonic digit morphogenesis GO:0042733 20 16 0,000 0,01993157 0,03629901 ! positive regulation of biomineral formation GO:0070169 23 16 0,000 0,01993157 0,03627117 ! regulation of vasodilation GO:0042312 26 16 0,000 0,01993157 0,03624338 ! DNA replication initiation GO:0006270 26 16 0,000 0,01993157 0,03621563 ! DNA unwinding during replication GO:0006268 24 16 0,000 0,01993157 0,03618792 ! regulation of steroid metabolic process GO:0019218 23 16 0,000 0,01993157 0,03616025 ! neuron recognition GO:0008038 27 16 0,000 0,01993157 0,03613263 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 22 16 0,000 0,01993157 0,03610505 ! DNA fragmentation involved in apoptosis GO:0006309 20 16 0,000 0,01993157 0,03607751 ! G1 phase GO:0051318 28 16 0,000 0,01993157 0,03605001 ! cellular amino acid derivative catabolic process GO:0042219 31 16 0,000 0,01993157 0,03602255 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,01993157 0,03599514 GO:0006626|protein targeting to mitochondrion, ! positive regulation of oxidoreductase activity GO:0051353 22 16 0,000 0,01993157 0,03596776 ! negative regulation of blood coagulation GO:0030195 21 16 0,000 0,01993157 0,03594043 ! negative regulation of tissue remodeling GO:0034104 35 16 0,000 0,01993157 0,03591314 ! NADP metabolic process GO:0006739 22 16 0,000 0,01993157 0,0358859 ! neuromuscular synaptic transmission GO:0007274 31 16 0,000 0,01993157 0,03585869 ! synaptic transmission, cholinergic GO:0007271 24 16 0,000 0,01993157 0,03583152 ! folic acid and derivative metabolic process GO:0006760 18 16 0,000 0,01993157 0,0358044 ! regulation of T-helper cell differentiation GO:0045622 25 16 0,000 0,01993157 0,03577731 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,01993157 0,03575027 ! aspartate family amino acid biosynthetic process GO:0009067 19 16 0,000 0,01993157 0,03572327 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 24 16 0,000 0,01993157 0,03569631 ! positive regulation of neuron apoptosis GO:0043525 30 16 0,000 0,01993157 0,03566939 ! regulation of blood vessel endothelial cell migration GO:0043535 37 16 0,000 0,01993157 0,03564251 ! RNA 3'-end processing GO:0031123 23 16 0,000 0,01993157 0,03561567 ! defense response to virus GO:0051607 28 16 0,000 0,01993157 0,03558887 ! peptide hormone secretion GO:0030072 26 16 0,000 0,01993157 0,03556211 ! positive regulation of protein complex assembly GO:0031334 26 17 0,000 0,02116454 0,03773363 ! regulation of lipid biosynthetic process GO:0046890 22 17 0,000 0,02116454 0,0377053 ! negative regulation of cell cycle process GO:0010948 37 17 0,000 0,02116454 0,03767702 ! zinc ion transport GO:0006829 22 17 0,000 0,02116454 0,03764877 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02116454 0,03762057 ! protein amino acid deacetylation GO:0006476 23 17 0,000 0,02116454 0,03759241 ! heterophilic cell adhesion GO:0007157 38 17 0,000 0,02116454 0,0375643 ! protein amino acid acetylation GO:0006473 33 17 0,000 0,02116454 0,03753622 ! regulation of neurotransmitter secretion GO:0046928 32 17 0,000 0,02116454 0,03750819 ! forelimb morphogenesis GO:0035136 20 17 0,000 0,02116454 0,0374802 ! negative regulation of ion transport GO:0043271 19 17 0,000 0,02116454 0,03745225 ! regulation of muscle cell differentiation GO:0051147 26 17 0,000 0,02116454 0,03742434 ! adult walking behavior GO:0007628 30 17 0,000 0,02116454 0,03739647 ! patterning of blood vessels GO:0001569 27 17 0,000 0,02116454 0,03736865 ! mechanoreceptor differentiation GO:0042490 32 17 0,000 0,02116454 0,03734086 ! cellular response to hydrogen peroxide GO:0070301 25 17 0,000 0,02116454 0,03731312 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 25 17 0,000 0,02116454 0,03728542 ! retinoid metabolic process GO:0001523 22 17 0,000 0,02116454 0,03725776 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 26 17 0,000 0,02116454 0,03723014 ! positive regulation of proteolysis GO:0045862 21 17 0,000 0,02116454 0,03720257 ! cardiac muscle tissue development GO:0048738 27 17 0,000 0,02116454 0,03717503 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02116454 0,03714753 ! protein polyubiquitination GO:0000209 31 17 0,000 0,02116454 0,03712008 ! cerebral cortex development GO:0021987 34 17 0,000 0,02116454 0,03709266 ! complement activation, alternative pathway GO:0006957 17 17 0,000 0,02116454 0,03706529 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02116454 0,03703795 ! fructose metabolic process GO:0006000 24 17 0,000 0,02116454 0,03701066 ! membrane budding GO:0006900 30 17 0,000 0,02116454 0,0369834 ! neuromuscular junction development GO:0007528 25 17 0,000 0,02116454 0,03695619 ! L-amino acid transport GO:0015807 27 17 0,000 0,02116454 0,03692902 ! regulation of protein binding GO:0043393 29 17 0,000 0,02116454 0,03690188 ! peptide secretion GO:0002790 30 17 0,000 0,02116454 0,03687479 ! stem cell differentiation GO:0048863 40 17 0,000 0,02116454 0,03684774 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02116454 0,03682072 ! intermediate filament-based process GO:0045103 29 17 0,000 0,02116454 0,03679375 ! protein export from nucleus GO:0006611 26 17 0,000 0,02116454 0,03676681 ! nucleotide-excision repair, DNA gap filling GO:0006297 23 17 0,000 0,02116454 0,03673991 ! diencephalon development GO:0021536 27 17 0,000 0,02116454 0,03671306 ! oogenesis GO:0048477 25 17 0,000 0,02116454 0,03668624 ! long-chain fatty acid transport GO:0015909 25 17 0,000 0,02116454 0,03665946 ! peptide biosynthetic process GO:0043043 22 17 0,000 0,02116454 0,03663272 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02116454 0,03660602 GO:0046467|membrane lipid biosynthetic process, ! biomineral formation GO:0031214 21 17 0,000 0,02116454 0,03657936 ! vitamin A metabolic process GO:0006776 23 17 0,000 0,02116454 0,03655274 ! steroid catabolic process GO:0006706 24 17 0,000 0,02116454 0,03652616 ! porphyrin biosynthetic process GO:0006779 24 17 0,000 0,02116454 0,03649961 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 23 17 0,000 0,02116454 0,0364731 ! nerve development GO:0021675 20 17 0,000 0,02116454 0,03644664 ! negative regulation of homeostatic process GO:0032845 29 17 0,000 0,02116454 0,03642021 ! regulation of mitotic metaphase/anaphase transition GO:0030071 33 17 0,000 0,02116454 0,03639381 ! protein secretion GO:0009306 32 18 0,000 0,02239603 0,03848355 ! regulation of glucose metabolic process GO:0010906 25 18 0,000 0,02239603 0,0384557 ! positive regulation of cell killing GO:0031343 27 18 0,000 0,02239603 0,0384279 ! negative regulation of defense response GO:0031348 21 18 0,000 0,02239603 0,03840013 ! pteridine and derivative metabolic process GO:0042558 23 18 0,000 0,02239603 0,03837241 ! positive regulation of anti-apoptosis GO:0045768 33 18 0,000 0,02239603 0,03834472 ! metencephalon development GO:0022037 25 18 0,000 0,02239603 0,03831707 ! positive regulation of hormone secretion GO:0046887 28 18 0,000 0,02239603 0,03828947 ! hormone secretion GO:0046879 28 18 0,000 0,02239603 0,0382619 ! 2'-deoxyribonucleotide metabolic process GO:0009394 24 18 0,000 0,02239603 0,03823438 GO:0019692|deoxyribose phosphate metabolic process, ! signal complex assembly GO:0007172 32 18 0,000 0,02239603 0,03820689 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 27 18 0,000 0,02239603 0,03817944 ! intra-Golgi vesicle-mediated transport GO:0006891 28 18 0,000 0,02239603 0,03815203 ! protein amino acid ADP-ribosylation GO:0006471 30 18 0,000 0,02239603 0,03812466 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02239603 0,03809734 ! transcription from RNA polymerase III promoter GO:0006383 36 18 0,000 0,02239603 0,03807005 ! regulation of postsynaptic membrane potential GO:0060078 31 18 0,000 0,02239603 0,03804279 ! glial cell development GO:0021782 31 18 0,000 0,02239603 0,03801558 ! keratinization GO:0031424 19 18 0,000 0,02239603 0,03798841 ! regulation of systemic arterial blood pressure by hormone GO:0001990 27 18 0,000 0,02239603 0,03796127 GO:0050886|endocrine process, ! myoblast differentiation GO:0045445 31 18 0,000 0,02239603 0,03793418 ! inactivation of MAPK activity GO:0000188 28 18 0,000 0,02239603 0,03790712 ! negative regulation of epithelial cell proliferation GO:0050680 36 18 0,000 0,02239603 0,0378801 ! vacuolar transport GO:0007034 26 18 0,000 0,02239603 0,03785312 ! pigmentation during development GO:0048066 35 18 0,000 0,02239603 0,03782618 ! cell-substrate junction assembly GO:0007044 45 18 0,000 0,02239603 0,03779928 ! cellular macromolecular complex disassembly GO:0034623 30 18 0,000 0,02239603 0,03777241 ! fucose metabolic process GO:0006004 27 18 0,000 0,02239603 0,03774558 ! actin filament bundle formation GO:0051017 30 18 0,000 0,02239603 0,0377188 ! body fluid secretion GO:0007589 27 18 0,000 0,02239603 0,03769204 ! regulation of dephosphorylation GO:0035303 38 18 0,000 0,02239603 0,03766533 ! NLS-bearing substrate import into nucleus GO:0006607 40 18 0,000 0,02239603 0,03763866 ! behavioral interaction between organisms GO:0051705 26 18 0,000 0,02239603 0,03761202 ! negative regulation of immune response GO:0050777 33 18 0,000 0,02239603 0,03758542 ! heart process GO:0003015 32 18 0,000 0,02239603 0,03755886 GO:0060047|heart contraction, ! regulation of T cell mediated immunity GO:0002709 39 18 0,000 0,02239603 0,03753233 ! sensory perception of pain GO:0019233 26 18 0,000 0,02239603 0,03750585 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 18 0,000 0,02239603 0,0374794 ! ribosomal small subunit biogenesis GO:0042274 22 18 0,000 0,02239603 0,03745298 ! somitogenesis GO:0001756 25 18 0,000 0,02239603 0,03742661 ! neural crest cell migration GO:0001755 28 18 0,000 0,02239603 0,03740027 ! neutrophil chemotaxis GO:0030593 26 18 0,000 0,02239603 0,03737397 ! positive regulation of intracellular transport GO:0032388 30 18 0,000 0,02239603 0,0373477 ! negative regulation of intracellular transport GO:0032387 31 18 0,000 0,02239603 0,03732148 ! synaptogenesis GO:0007416 28 18 0,000 0,02239603 0,03729529 ! cell-cell junction organization GO:0045216 28 18 0,000 0,02239603 0,03726913 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02239603 0,03724302 ! purine nucleotide catabolic process GO:0006195 27 18 0,000 0,02239603 0,03721693 ! proximal/distal pattern formation GO:0009954 28 18 0,000 0,02239603 0,03719089 ! regulation of generation of precursor metabolites and energy GO:0043467 29 18 0,000 0,02239603 0,03716488 ! aromatic compound catabolic process GO:0019439 26 18 0,000 0,02239603 0,03713891 ! somatic recombination of immunoglobulin gene segments GO:0016447 28 18 0,000 0,02239603 0,03711298 ! gut development GO:0048565 29 18 0,000 0,02239603 0,03708708 ! negative regulation of leukocyte proliferation GO:0070664 35 18 0,000 0,02239603 0,03706122 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! antigen receptor-mediated signaling pathway GO:0050851 33 18 0,000 0,02239603 0,03703539 ! positive regulation of synaptic transmission GO:0050806 26 18 0,000 0,02239603 0,0370096 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 28 19 0,000 0,02362603 0,03901501 ! positive regulation of translation GO:0045727 29 19 0,000 0,02362603 0,03898788 ! positive regulation of cell size GO:0045793 26 19 0,000 0,02362603 0,03896079 ! phosphatidylinositol metabolic process GO:0046488 24 19 0,000 0,02362603 0,03893373 ! glycerol metabolic process GO:0006071 22 19 0,000 0,02362603 0,03890671 ! phosphoinositide phosphorylation GO:0046854 26 19 0,000 0,02362603 0,03887973 ! regulation of neuronal synaptic plasticity GO:0048168 37 19 0,000 0,02362603 0,03885279 ! endothelial cell migration GO:0043542 24 19 0,000 0,02362603 0,03882588 ! glycosaminoglycan biosynthetic process GO:0006024 27 19 0,000 0,02362603 0,03879901 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 23 19 0,000 0,02362603 0,03877218 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 19 0,000 0,02362603 0,03874539 ! memory GO:0007613 28 19 0,000 0,02362603 0,03871863 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 19 0,000 0,02362603 0,03869191 ! pancreas development GO:0031016 27 19 0,000 0,02362603 0,03866522 ! response to carbohydrate stimulus GO:0009743 28 19 0,000 0,02362603 0,03863858 ! DNA duplex unwinding GO:0032508 28 19 0,000 0,02362603 0,03861196 GO:0032392|DNA geometric change, ! peroxisome organization GO:0007031 30 19 0,000 0,02362603 0,03858539 ! central nervous system neuron development GO:0021954 33 19 0,000 0,02362603 0,03855885 ! polysaccharide catabolic process GO:0000272 24 19 0,000 0,02362603 0,03853235 ! actin polymerization or depolymerization GO:0008154 32 19 0,000 0,02362603 0,03850589 ! vesicle docking during exocytosis GO:0006904 25 19 0,000 0,02362603 0,03847946 ! heme metabolic process GO:0042168 29 19 0,000 0,02362603 0,03845307 ! negative regulation of protein catabolic process GO:0042177 29 19 0,000 0,02362603 0,03842671 ! response to lipopolysaccharide GO:0032496 28 19 0,000 0,02362603 0,03840039 ! response to fungus GO:0009620 21 19 0,000 0,02362603 0,03837411 ! peptide cross-linking GO:0018149 35 19 0,000 0,02362603 0,03834786 ! ventricular cardiac muscle morphogenesis GO:0055010 25 19 0,000 0,02362603 0,03832165 ! determination of left/right symmetry GO:0007368 24 19 0,000 0,02362603 0,03829547 ! prostaglandin metabolic process GO:0006693 34 19 0,000 0,02362603 0,03826933 GO:0006692|prostanoid metabolic process, ! regulation of immunoglobulin mediated immune response GO:0002889 29 19 0,000 0,02362603 0,03824323 GO:0002712|regulation of B cell mediated immunity, ! detection of chemical stimulus GO:0009593 28 19 0,000 0,02362603 0,03821716 ! vitamin transport GO:0051180 26 19 0,000 0,02362603 0,03819113 ! sarcomere organization GO:0045214 26 19 0,000 0,02362603 0,03816513 ! positive regulation of myeloid cell differentiation GO:0045639 50 19 0,000 0,02362603 0,03813917 ! regulation of immunoglobulin production GO:0002637 29 19 0,000 0,02362603 0,03811324 ! positive regulation of transmission of nerve impulse GO:0051971 27 19 0,000 0,02362603 0,03808735 ! leukotriene biosynthetic process GO:0019370 27 19 0,000 0,02362603 0,03806149 GO:0043450|alkene biosynthetic process, ! regulation of glucose import GO:0046324 23 19 0,000 0,02362603 0,03803567 GO:0010827|regulation of glucose transport, ! negative regulation of coagulation GO:0050819 25 19 0,000 0,02362603 0,03800988 ! oligosaccharide metabolic process GO:0009311 35 20 0,000 0,02485455 0,03995924 ! positive regulation of angiogenesis GO:0045766 42 20 0,000 0,02485455 0,03993218 ! determination of bilateral symmetry GO:0009855 26 20 0,000 0,02485455 0,03990517 GO:0009799|determination of symmetry, ! N-acetylglucosamine metabolic process GO:0006044 25 20 0,000 0,02485455 0,03987819 ! lipid phosphorylation GO:0046834 28 20 0,000 0,02485455 0,03985124 ! aminoglycan biosynthetic process GO:0006023 28 20 0,000 0,02485455 0,03982433 ! hindlimb morphogenesis GO:0035137 35 20 0,000 0,02485455 0,03979746 ! C21-steroid hormone metabolic process GO:0008207 25 20 0,000 0,02485455 0,03977063 ! calcium-independent cell-cell adhesion GO:0016338 23 20 0,000 0,02485455 0,03974383 ! response to alkaloid GO:0043279 34 20 0,000 0,02485455 0,03971706 ! sensory perception of taste GO:0050909 26 20 0,000 0,02485455 0,03969033 ! response to retinoic acid GO:0032526 27 20 0,000 0,02485455 0,03966364 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 20 0,000 0,02485455 0,03963699 ! cellular response to reactive oxygen species GO:0034614 32 20 0,000 0,02485455 0,03961037 ! D-ribose metabolic process GO:0006014 27 20 0,000 0,02485455 0,03958378 ! cell structure disassembly during apoptosis GO:0006921 25 20 0,000 0,02485455 0,03955723 ! chromosome condensation GO:0030261 32 20 0,000 0,02485455 0,03953072 ! peptidyl-serine phosphorylation GO:0018105 31 20 0,000 0,02485455 0,03950424 ! sex determination GO:0007530 32 20 0,000 0,02485455 0,0394778 ! plasma membrane fusion GO:0045026 24 20 0,000 0,02485455 0,0394514 ! fatty acid beta-oxidation GO:0006635 32 20 0,000 0,02485455 0,03942502 ! positive regulation of alpha-beta T cell differentiation GO:0046638 29 20 0,000 0,02485455 0,03939869 ! cytolysis GO:0019835 21 20 0,000 0,02485455 0,03937239 ! renal system process GO:0003014 35 20 0,000 0,02485455 0,03934612 ! vasodilation GO:0042311 36 20 0,000 0,02485455 0,03931989 ! negative regulation of angiogenesis GO:0016525 38 20 0,000 0,02485455 0,0392937 ! detection of biotic stimulus GO:0009595 23 20 0,000 0,02485455 0,03926753 ! cellular response to nutrient levels GO:0031669 32 20 0,000 0,02485455 0,03924141 ! positive regulation of neurological system process GO:0031646 31 20 0,000 0,02485455 0,03921532 ! hormone transport GO:0009914 30 20 0,000 0,02485455 0,03918926 ! negative regulation of neuron differentiation GO:0045665 33 20 0,000 0,02485455 0,03916324 ! activation of JUN kinase activity GO:0007257 28 20 0,000 0,02485455 0,03913725 ! regulation of leukocyte mediated cytotoxicity GO:0001910 34 20 0,000 0,02485455 0,0391113 ! estrogen receptor signaling pathway GO:0030520 36 20 0,000 0,02485455 0,03908538 ! sperm-egg recognition GO:0035036 24 20 0,000 0,02485455 0,03905949 GO:0007339|binding of sperm to zona pellucida, ! embryonic organ morphogenesis GO:0048562 26 20 0,000 0,02485455 0,03903364 ! negative regulation of translation GO:0017148 28 20 0,000 0,02485455 0,03900783 ! cellular monovalent inorganic cation homeostasis GO:0030004 31 20 0,000 0,02485455 0,03898205 ! positive regulation of DNA replication GO:0045740 37 21 0,000 0,02608158 0,04087951 ! positive regulation of protein catabolic process GO:0045732 25 21 0,000 0,02608158 0,04085253 ! positive regulation of fibroblast proliferation GO:0048146 30 21 0,000 0,02608158 0,04082558 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,02608158 0,04079867 ! positive regulation of ossification GO:0045778 34 21 0,000 0,02608158 0,04077179 ! G2/M transition of mitotic cell cycle GO:0000086 34 21 0,000 0,02608158 0,04074495 ! iron ion transport GO:0006826 49 21 0,000 0,02608158 0,04071814 ! glucosamine metabolic process GO:0006041 26 21 0,000 0,02608158 0,04069137 ! microtubule-based transport GO:0010970 41 21 0,000 0,02608158 0,04066464 ! vesicle docking GO:0048278 28 21 0,000 0,02608158 0,04063794 ! regulation of carbohydrate metabolic process GO:0006109 31 21 0,000 0,02608158 0,04061127 GO:0010675|regulation of cellular carbohydrate metabolic process, ! ovarian follicle development GO:0001541 33 21 0,000 0,02608158 0,04058464 ! apoptotic mitochondrial changes GO:0008637 42 21 0,000 0,02608158 0,04055805 ! response to ethanol GO:0045471 38 21 0,000 0,02608158 0,04053149 ! positive regulation of epithelial cell proliferation GO:0050679 43 21 0,000 0,02608158 0,04050496 ! smooth muscle contraction GO:0006939 39 21 0,000 0,02608158 0,04047847 ! glutamine metabolic process GO:0006541 29 21 0,000 0,02608158 0,04045201 ! response to vitamin A GO:0033189 28 21 0,000 0,02608158 0,04042559 ! purine ribonucleoside metabolic process GO:0046128 30 21 0,000 0,02608158 0,0403992 GO:0042278|purine nucleoside metabolic process, ! neurotransmitter metabolic process GO:0042133 36 21 0,000 0,02608158 0,04037285 ! apoptotic nuclear changes GO:0030262 31 21 0,000 0,02608158 0,04034653 ! response to starvation GO:0042594 35 21 0,000 0,02608158 0,04032025 ! regulation of myeloid leukocyte differentiation GO:0002761 41 21 0,000 0,02608158 0,040294 ! leukotriene metabolic process GO:0006691 29 21 0,000 0,02608158 0,04026778 ! regulation of vasoconstriction GO:0019229 33 21 0,000 0,02608158 0,0402416 ! glycosphingolipid metabolic process GO:0006687 35 21 0,000 0,02608158 0,04021545 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 28 21 0,000 0,02608158 0,04018934 ! regulation of fatty acid metabolic process GO:0019217 32 21 0,000 0,02608158 0,04016326 ! visual learning GO:0008542 38 21 0,000 0,02608158 0,04013721 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 38 21 0,000 0,02608158 0,0401112 ! positive regulation of inflammatory response GO:0050729 38 21 0,000 0,02608158 0,04008522 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,02608158 0,04005927 ! neuromuscular process controlling balance GO:0050885 54 21 0,000 0,02608158 0,04003336 ! negative regulation of myeloid cell differentiation GO:0045638 29 21 0,000 0,02608158 0,04000749 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,02608158 0,03998164 ! aromatic amino acid family metabolic process GO:0009072 30 21 0,000 0,02608158 0,03995583 ! somatic diversification of immunoglobulins GO:0016445 31 21 0,000 0,02608158 0,03993005 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,02608158 0,03990431 ! negative regulation of T cell activation GO:0050868 35 21 0,000 0,02608158 0,0398786 ! regulation of microtubule polymerization or depolymerization GO:0031110 51 21 0,000 0,02608158 0,03985292 ! embryonic pattern specification GO:0009880 34 22 0,000 0,02730712 0,04169872 ! regulation of cell killing GO:0031341 37 22 0,000 0,02730712 0,0416719 ! regulation of anti-apoptosis GO:0045767 40 22 0,000 0,02730712 0,04164512 ! gluconeogenesis GO:0006094 26 22 0,000 0,02730712 0,04161837 ! DNA catabolic process, endonucleolytic GO:0000737 27 22 0,000 0,02730712 0,04159166 ! viral genome replication GO:0019079 31 22 0,000 0,02730712 0,04156498 ! nucleotide-excision repair, DNA damage removal GO:0000718 27 22 0,000 0,02730712 0,04153834 ! protein amino acid O-linked glycosylation GO:0006493 36 22 0,000 0,02730712 0,04151173 ! protein amino acid acylation GO:0043543 42 22 0,000 0,02730712 0,04148515 ! response to vitamin GO:0033273 31 22 0,000 0,02730712 0,04145861 ! molting cycle process GO:0022404 43 22 0,000 0,02730712 0,0414321 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of neurotransmitter transport GO:0051588 41 22 0,000 0,02730712 0,04140563 ! regeneration GO:0031099 37 22 0,000 0,02730712 0,04137919 ! phototransduction GO:0007602 29 22 0,000 0,02730712 0,04135278 ! regulation of DNA recombination GO:0000018 43 22 0,000 0,02730712 0,04132641 ! regulation of smooth muscle contraction GO:0006940 38 22 0,000 0,02730712 0,04130007 ! deoxyribonucleotide metabolic process GO:0009262 29 22 0,000 0,02730712 0,04127376 ! central nervous system neuron differentiation GO:0021953 39 22 0,000 0,02730712 0,04124749 ! cholesterol biosynthetic process GO:0006695 32 22 0,000 0,02730712 0,04122125 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 22 0,000 0,02730712 0,04119504 ! regulation of interleukin-6 production GO:0032675 25 22 0,000 0,02730712 0,04116887 ! regulation of interleukin-2 production GO:0032663 38 22 0,000 0,02730712 0,04114273 ! pallium development GO:0021543 43 22 0,000 0,02730712 0,04111663 ! positive regulation of locomotion GO:0040017 40 22 0,000 0,02730712 0,04109055 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! fatty acid transport GO:0015908 33 22 0,000 0,02730712 0,04106452 ! platelet activation GO:0030168 33 22 0,000 0,02730712 0,04103851 ! proteoglycan biosynthetic process GO:0030166 33 22 0,000 0,02730712 0,04101253 ! regulation of cytokine secretion GO:0050707 30 22 0,000 0,02730712 0,04098659 ! positive regulation of osteoblast differentiation GO:0045669 37 22 0,000 0,02730712 0,04096069 ! cellular alkene metabolic process GO:0043449 30 22 0,000 0,02730712 0,04093481 ! cell-cell recognition GO:0009988 28 22 0,000 0,02730712 0,04090897 ! pyrimidine nucleoside metabolic process GO:0006213 28 22 0,000 0,02730712 0,04088316 ! water-soluble vitamin biosynthetic process GO:0042364 28 22 0,000 0,02730712 0,04085738 ! neural tube closure GO:0001843 35 22 0,000 0,02730712 0,04083164 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 26 22 0,000 0,02730712 0,04080592 ! regulation of multi-organism process GO:0043900 35 22 0,000 0,02730712 0,04078024 ! protein tetramerization GO:0051262 43 22 0,000 0,02730712 0,04075459 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 36 23 0,000 0,02853119 0,04255469 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid metabolic process GO:0000096 31 23 0,000 0,02853119 0,04252796 ! reciprocal meiotic recombination GO:0007131 41 23 0,000 0,02853119 0,04250127 ! cellular aldehyde metabolic process GO:0006081 32 23 0,000 0,02853119 0,0424746 ! positive regulation of bone remodeling GO:0046852 37 23 0,000 0,02853119 0,04244797 ! cellular polysaccharide biosynthetic process GO:0033692 29 23 0,000 0,02853119 0,04242138 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 31 23 0,000 0,02853119 0,04239481 ! dicarboxylic acid metabolic process GO:0043648 36 23 0,000 0,02853119 0,04236828 ! regulation of chemotaxis GO:0050920 41 23 0,000 0,02853119 0,04234179 ! regulation of receptor-mediated endocytosis GO:0048259 26 23 0,000 0,02853119 0,04231532 ! tube lumen formation GO:0035148 37 23 0,000 0,02853119 0,04228889 ! macromolecular complex disassembly GO:0032984 39 23 0,000 0,02853119 0,04226249 ! dendrite development GO:0016358 41 23 0,000 0,02853119 0,04223613 ! vasculogenesis GO:0001570 38 23 0,000 0,02853119 0,0422098 ! microtubule organizing center organization GO:0031023 30 23 0,000 0,02853119 0,0421835 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 50 23 0,000 0,02853119 0,04215723 ! lysosome organization GO:0007040 41 23 0,000 0,02853119 0,042131 ! digestive system process GO:0022600 35 23 0,000 0,02853119 0,0421048 ! positive regulation of cytoskeleton organization GO:0051495 43 23 0,000 0,02853119 0,04207863 ! vesicle targeting GO:0006903 35 23 0,000 0,02853119 0,04205249 ! response to corticosteroid stimulus GO:0031960 37 23 0,000 0,02853119 0,04202639 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 36 23 0,000 0,02853119 0,04200032 ! regulation of endothelial cell migration GO:0010594 44 23 0,000 0,02853119 0,04197428 ! regulation of viral reproduction GO:0050792 33 23 0,000 0,02853119 0,04194828 ! regulation of insulin secretion GO:0050796 30 23 0,000 0,02853119 0,0419223 ! regulation of alpha-beta T cell differentiation GO:0046637 35 23 0,000 0,02853119 0,04189636 ! cardiac muscle tissue morphogenesis GO:0055008 29 23 0,000 0,02853119 0,04187045 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 42 23 0,000 0,02853119 0,04184457 ! membrane depolarization GO:0051899 40 23 0,000 0,02853119 0,04181873 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,02853119 0,04179291 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 39 23 0,000 0,02853119 0,04176713 ! regulation of ARF GTPase activity GO:0032312 35 23 0,000 0,02853119 0,04174138 ! DNA modification GO:0006304 33 23 0,000 0,02853119 0,04171566 ! collagen fibril organization GO:0030199 50 23 0,000 0,02853119 0,04168997 ! synaptic vesicle transport GO:0048489 45 23 0,000 0,02853119 0,04166432 ! cellular response to extracellular stimulus GO:0031668 37 23 0,000 0,02853119 0,04163869 ! peptidyl-serine modification GO:0018209 37 23 0,000 0,02853119 0,0416131 ! nerve-nerve synaptic transmission GO:0007270 42 23 0,000 0,02853119 0,04158754 ! fat-soluble vitamin metabolic process GO:0006775 29 23 0,000 0,02853119 0,04156201 ! positive regulation of B cell activation GO:0050871 36 23 0,000 0,02853119 0,04153651 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,02853119 0,04151105 ! collagen catabolic process GO:0030574 29 23 0,000 0,02853119 0,04148561 ! glutamine family amino acid catabolic process GO:0009065 34 23 0,000 0,02853119 0,04146021 ! aspartate family amino acid metabolic process GO:0009066 27 23 0,000 0,02853119 0,04143483 ! porphyrin metabolic process GO:0006778 37 23 0,000 0,02853119 0,04140949 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 39 23 0,000 0,02853119 0,04138418 ! blastocyst development GO:0001824 41 23 0,000 0,02853119 0,0413589 ! actin filament-based movement GO:0030048 37 23 0,000 0,02853119 0,04133365 ! protein stabilization GO:0050821 34 23 0,000 0,02853119 0,04130843 ! protein import into nucleus, docking GO:0000059 45 24 0,000 0,02975378 0,04305227 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 30 24 0,000 0,02975378 0,04302603 ! myelination GO:0042552 39 24 0,000 0,02975378 0,04299983 ! initiation of viral infection GO:0019059 47 24 0,000 0,02975378 0,04297366 ! regulation of transmembrane transport GO:0034762 31 24 0,000 0,02975378 0,04294752 ! leukocyte adhesion GO:0007159 49 24 0,000 0,02975378 0,04292141 ! glutamate signaling pathway GO:0007215 37 24 0,000 0,02975378 0,04289533 ! regulation of transcription factor import into nucleus GO:0042990 49 24 0,000 0,02975378 0,04286929 ! visual behavior GO:0007632 42 24 0,000 0,02975378 0,04284328 ! spinal cord development GO:0021510 41 24 0,000 0,02975378 0,04281729 ! immune response-activating cell surface receptor signaling pathway GO:0002429 39 24 0,000 0,02975378 0,04279135 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 46 24 0,000 0,02975378 0,04276543 ! multicellular organismal response to stress GO:0033555 42 24 0,000 0,02975378 0,04273954 ! regulation of nitric oxide biosynthetic process GO:0045428 42 24 0,000 0,02975378 0,04271368 ! negative regulation of DNA replication GO:0008156 39 24 0,000 0,02975378 0,04268786 ! cell aging GO:0007569 38 24 0,000 0,02975378 0,04266207 ! osteoblast differentiation GO:0001649 43 24 0,000 0,02975378 0,0426363 ! response to toxin GO:0009636 38 24 0,000 0,02975378 0,04261057 ! primary neural tube formation GO:0014020 37 24 0,000 0,02975378 0,04258487 ! vitamin biosynthetic process GO:0009110 30 24 0,000 0,02975378 0,0425592 ! positive regulation of alpha-beta T cell activation GO:0046635 40 24 0,000 0,02975378 0,04253357 ! cellular response to oxidative stress GO:0034599 38 24 0,000 0,02975378 0,04250796 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 24 0,000 0,02975378 0,04248238 ! fibroblast growth factor receptor signaling pathway GO:0008543 45 24 0,000 0,02975378 0,04245684 ! pentose metabolic process GO:0019321 33 24 0,000 0,02975378 0,04243132 ! immunoglobulin production GO:0002377 37 24 0,000 0,02975378 0,04240584 GO:0002440|production of molecular mediator of immune response, ! regulation of response to biotic stimulus GO:0002831 45 24 0,000 0,02975378 0,04238038 ! positive regulation of protein secretion GO:0050714 29 24 0,000 0,02975378 0,04235496 ! positive regulation of adaptive immune response GO:0002821 44 24 0,000 0,02975378 0,04232957 ! regulation of blood coagulation GO:0030193 37 24 0,000 0,02975378 0,04230421 ! positive regulation of tissue remodeling GO:0034105 41 24 0,000 0,02975378 0,04227887 ! group transfer coenzyme metabolic process GO:0006752 29 24 0,000 0,02975378 0,04225357 ! response to molecule of bacterial origin GO:0002237 38 24 0,000 0,02975378 0,0422283 ! positive regulation of JUN kinase activity GO:0043507 33 24 0,000 0,02975378 0,04220306 ! regulation of fibroblast proliferation GO:0048145 39 25 0,000 0,03097489 0,04390885 ! neuron fate commitment GO:0048663 38 25 0,000 0,03097489 0,04388264 ! pyruvate metabolic process GO:0006090 32 25 0,000 0,03097489 0,04385645 ! superoxide metabolic process GO:0006801 33 25 0,000 0,03097489 0,0438303 ! detection of light stimulus involved in sensory perception GO:0050962 32 25 0,000 0,03097489 0,04380418 GO:0050908|detection of light stimulus involved in visual perception, ! regulation of cell-matrix adhesion GO:0001952 57 25 0,000 0,03097489 0,04377809 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 44 25 0,000 0,03097489 0,04375203 ! mitochondrial membrane organization GO:0007006 42 25 0,000 0,03097489 0,04372601 ! vacuole organization GO:0007033 43 25 0,000 0,03097489 0,04370001 ! receptor metabolic process GO:0043112 40 25 0,000 0,03097489 0,04367404 ! barbed-end actin filament capping GO:0051016 41 25 0,000 0,03097489 0,04364811 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 35 25 0,000 0,03097489 0,04362221 ! regulation of behavior GO:0050795 45 25 0,000 0,03097489 0,04359633 ! hydrogen peroxide metabolic process GO:0042743 35 25 0,000 0,03097489 0,04357049 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 45 25 0,000 0,03097489 0,04354468 ! lymphocyte proliferation GO:0046651 42 25 0,000 0,03097489 0,0435189 ! negative regulation of phosphorylation GO:0042326 46 25 0,000 0,03097489 0,04349315 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,03097489 0,04346743 ! regulation of tumor necrosis factor production GO:0032680 32 25 0,000 0,03097489 0,04344174 ! positive regulation of nuclear division GO:0051785 41 25 0,000 0,03097489 0,04341608 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 38 25 0,000 0,03097489 0,04339045 ! camera-type eye morphogenesis GO:0048593 43 25 0,000 0,03097489 0,04336485 ! negative regulation of catabolic process GO:0009895 37 25 0,000 0,03097489 0,04333928 ! regulation of amine transport GO:0051952 44 25 0,000 0,03097489 0,04331374 ! liver development GO:0001889 44 25 0,000 0,03097489 0,04328823 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 38 26 0,000 0,03219453 0,04496622 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 31 26 0,000 0,03219453 0,04493977 ! positive regulation of cell projection organization GO:0031346 43 26 0,000 0,03219453 0,04491335 ! regulation of cellular catabolic process GO:0031329 39 26 0,000 0,03219453 0,04488696 ! regulation of interferon-gamma production GO:0032649 33 26 0,000 0,03219453 0,04486061 ! cellular iron ion homeostasis GO:0006879 47 26 0,000 0,03219453 0,04483428 ! epidermal growth factor receptor signaling pathway GO:0007173 42 26 0,000 0,03219453 0,04480798 ! amino sugar metabolic process GO:0006040 32 26 0,000 0,03219453 0,04478172 ! protein amino acid alkylation GO:0008213 40 26 0,000 0,03219453 0,04475548 GO:0006479|protein amino acid methylation, ! odontogenesis of dentine-containing tooth GO:0042475 43 26 0,000 0,03219453 0,04472928 ! insulin receptor signaling pathway GO:0008286 48 26 0,000 0,03219453 0,04470311 ! sperm motility GO:0030317 31 26 0,000 0,03219453 0,04467697 ! peptidyl-tyrosine phosphorylation GO:0018108 42 26 0,000 0,03219453 0,04465085 ! male gonad development GO:0008584 39 26 0,000 0,03219453 0,04462477 ! neural crest cell development GO:0014032 44 26 0,000 0,03219453 0,04459872 GO:0014033|neural crest cell differentiation, ! base-excision repair GO:0006284 35 26 0,000 0,03219453 0,0445727 ! cell fate determination GO:0001709 54 26 0,000 0,03219453 0,04454671 ! regulation of chromosome organization GO:0033044 37 26 0,000 0,03219453 0,04452075 ! regulation of oxidoreductase activity GO:0051341 42 26 0,000 0,03219453 0,04449482 ! detection of visible light GO:0009584 33 26 0,000 0,03219453 0,04446892 ! spermatid development GO:0007286 40 26 0,000 0,03219453 0,04444306 ! regulation of bone mineralization GO:0030500 38 26 0,000 0,03219453 0,04441722 ! regulation of osteoblast differentiation GO:0045667 41 26 0,000 0,03219453 0,04439141 ! acetyl-CoA catabolic process GO:0046356 38 26 0,000 0,03219453 0,04436563 GO:0006099|tricarboxylic acid cycle, ! regulation of JUN kinase activity GO:0043506 39 26 0,000 0,03219453 0,04433988 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,03341269 0,0459909 ! spliceosomal snRNP biogenesis GO:0000387 38 27 0,000 0,03341269 0,04596424 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 47 27 0,000 0,03341269 0,04593761 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 42 27 0,000 0,03341269 0,04591101 ! membrane docking GO:0022406 40 27 0,000 0,03341269 0,04588444 ! circadian rhythm GO:0007623 44 27 0,000 0,03341269 0,0458579 ! regulation of endothelial cell proliferation GO:0001936 52 27 0,000 0,03341269 0,04583139 ! positive regulation of innate immune response GO:0045089 34 27 0,000 0,03341269 0,04580492 ! autophagy GO:0006914 36 27 0,000 0,03341269 0,04577847 ! myofibril assembly GO:0030239 40 27 0,000 0,03341269 0,04575205 GO:0055002|striated muscle cell development, ! negative regulation of phosphorus metabolic process GO:0010563 51 27 0,000 0,03341269 0,04572567 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 38 27 0,000 0,03341269 0,04569931 ! peptide transport GO:0015833 46 27 0,000 0,03341269 0,04567299 ! coenzyme catabolic process GO:0009109 40 27 0,000 0,03341269 0,0456467 ! regulation of peptide secretion GO:0002791 39 27 0,000 0,03341269 0,04562043 ! negative regulation of cell development GO:0010721 67 27 0,000 0,03341269 0,0455942 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 46 27 0,000 0,03341269 0,04556799 ! positive regulation of leukocyte mediated immunity GO:0002705 45 27 0,000 0,03341269 0,04554182 GO:0002708|positive regulation of lymphocyte mediated immunity, ! phospholipid transport GO:0015914 40 27 0,000 0,03341269 0,04551568 ! detection of light stimulus GO:0009583 35 27 0,000 0,03341269 0,04548956 ! glutathione metabolic process GO:0006749 35 27 0,000 0,03341269 0,04546348 ! lipid oxidation GO:0034440 39 27 0,000 0,03341269 0,04543743 GO:0019395|fatty acid oxidation, ! leukocyte proliferation GO:0070661 45 27 0,000 0,03341269 0,0454114 GO:0032943|mononuclear cell proliferation, ! telomere organization GO:0032200 39 27 0,000 0,03341269 0,04538541 GO:0000723|telomere maintenance, ! negative regulation of neuron apoptosis GO:0043524 48 27 0,000 0,03341269 0,04535945 ! protein import into nucleus, translocation GO:0000060 47 28 0,000 0,03462938 0,04698429 ! positive regulation of smooth muscle cell proliferation GO:0048661 45 28 0,000 0,03462938 0,04695744 ! translational initiation GO:0006413 48 28 0,000 0,03462938 0,04693062 ! negative regulation of actin filament depolymerization GO:0030835 44 28 0,000 0,03462938 0,04690383 ! acetyl-CoA metabolic process GO:0006084 42 28 0,000 0,03462938 0,04687708 ! regulation of pH GO:0006885 40 28 0,000 0,03462938 0,04685035 ! negative regulation of protein modification process GO:0031400 56 28 0,000 0,03462938 0,04682366 ! catechol metabolic process GO:0009712 46 28 0,000 0,03462938 0,04679699 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 43 28 0,000 0,03462938 0,04677036 ! cellular carbohydrate biosynthetic process GO:0034637 37 28 0,000 0,03462938 0,04674375 ! iron ion homeostasis GO:0055072 49 28 0,000 0,03462938 0,04671718 ! regulation of biomineral formation GO:0070167 40 28 0,000 0,03462938 0,04669063 ! peptidyl-tyrosine modification GO:0018212 44 28 0,000 0,03462938 0,04666412 ! neurotransmitter secretion GO:0007269 41 28 0,000 0,03462938 0,04663764 ! negative regulation of transcription regulator activity GO:0090048 48 28 0,000 0,03462938 0,04661118 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of lymphocyte activation GO:0051250 48 28 0,000 0,03462938 0,04658476 ! gene silencing GO:0016458 47 28 0,000 0,03462938 0,04655837 ! regulation of coagulation GO:0050818 42 28 0,000 0,03462938 0,046532 ! negative regulation of actin filament polymerization GO:0030837 45 29 0,000 0,0358446 0,04813765 ! phenol metabolic process GO:0018958 47 29 0,000 0,0358446 0,04811043 ! positive regulation of cell adhesion GO:0045785 54 29 0,000 0,0358446 0,04808323 ! icosanoid biosynthetic process GO:0046456 45 29 0,000 0,0358446 0,04805606 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 39 29 0,000 0,0358446 0,04802893 ! calcium-dependent cell-cell adhesion GO:0016339 36 29 0,000 0,0358446 0,04800182 ! negative regulation of response to external stimulus GO:0032102 39 29 0,000 0,0358446 0,04797475 ! cholesterol transport GO:0030301 48 29 0,000 0,0358446 0,04794771 GO:0015918|sterol transport, ! cholesterol homeostasis GO:0042632 53 29 0,000 0,0358446 0,04792069 GO:0055092|sterol homeostasis, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 39 29 0,000 0,0358446 0,04789371 ! GPI anchor metabolic process GO:0006505 47 29 0,000 0,0358446 0,04786676 ! complement activation, classical pathway GO:0006958 39 29 0,000 0,0358446 0,04783984 ! multicellular organismal catabolic process GO:0044243 36 29 0,000 0,0358446 0,04781295 ! respiratory gaseous exchange GO:0007585 51 29 0,000 0,0358446 0,04778609 ! triglyceride metabolic process GO:0006641 38 29 0,000 0,0358446 0,04775926 ! response to ionizing radiation GO:0010212 55 29 0,000 0,0358446 0,04773245 ! muscle cell development GO:0055001 42 29 0,000 0,0358446 0,04770568 ! response to organic cyclic substance GO:0014070 53 29 0,000 0,0358446 0,04767894 ! regulation of systemic arterial blood pressure GO:0003073 52 29 0,000 0,0358446 0,04765223 ! mesoderm formation GO:0001707 52 29 0,000 0,0358446 0,04762555 ! response to estradiol stimulus GO:0032355 38 29 0,000 0,0358446 0,0475989 ! positive regulation of MAPKKK cascade GO:0043410 45 29 0,000 0,0358446 0,04757228 ! regulation of microtubule cytoskeleton organization GO:0070507 61 29 0,000 0,0358446 0,04754569 ! ensheathment of neurons GO:0007272 48 29 0,000 0,0358446 0,04751912 GO:0008366|axon ensheathment, ! serine family amino acid metabolic process GO:0009069 41 29 0,000 0,0358446 0,04749259 ! spermatid differentiation GO:0048515 45 29 0,000 0,0358446 0,04746609 ! myeloid leukocyte activation GO:0002274 44 29 0,000 0,0358446 0,04743962 ! neural tube formation GO:0001841 46 29 0,000 0,0358446 0,04741317 ! regulation of actin filament depolymerization GO:0030834 47 30 0,000 0,03705835 0,04899135 ! organic anion transport GO:0015711 50 30 0,000 0,03705835 0,04896407 ! cell junction assembly GO:0034329 65 30 0,000 0,03705835 0,04893682 ! acute-phase response GO:0006953 49 30 0,000 0,03705835 0,0489096 ! segmentation GO:0035282 43 30 0,000 0,03705835 0,04888242 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 56 30 0,000 0,03705835 0,04885526 ! immune response-activating signal transduction GO:0002757 45 30 0,000 0,03705835 0,04882813 ! regulation of protein import into nucleus GO:0042306 56 30 0,000 0,03705835 0,04880104 ! regulation of production of molecular mediator of immune response GO:0002700 47 30 0,000 0,03705835 0,04877397 ! ceramide metabolic process GO:0006672 47 30 0,000 0,03705835 0,04874693 ! formation of primary germ layer GO:0001704 54 30 0,000 0,03705835 0,04871993 ! nicotinamide metabolic process GO:0006769 47 30 0,000 0,03705835 0,04869295 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 50 30 0,000 0,03705835 0,048666 ! fatty acid catabolic process GO:0009062 45 30 0,000 0,03705835 0,04863908 ! regulation of calcium ion transport GO:0051924 40 30 0,000 0,03705835 0,0486122 ! negative regulation of protein polymerization GO:0032272 47 30 0,000 0,03705835 0,04858534 ! negative regulation of protein transport GO:0051224 53 30 0,000 0,03705835 0,04855851 ! response to heat GO:0009408 43 30 0,000 0,03705835 0,04853171 ! establishment of vesicle localization GO:0051650 48 30 0,000 0,03705835 0,04850494 ! alkaloid metabolic process GO:0009820 48 31 0,000 0,03827063 0,05006407 ! response to hydrogen peroxide GO:0042542 48 31 0,000 0,03827063 0,05003648 ! post-embryonic development GO:0009791 50 31 0,000 0,03827063 0,05000893 ! inner ear morphogenesis GO:0042472 43 31 0,000 0,03827063 0,04998141 ! regulation of innate immune response GO:0045088 42 31 0,000 0,03827063 0,04995391 ! ovulation cycle process GO:0022602 46 31 0,000 0,03827063 0,04992645 ! mesoderm morphogenesis GO:0048332 54 31 0,000 0,03827063 0,04989902 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 42 31 0,000 0,03827063 0,04987162 ! immune response-regulating signal transduction GO:0002764 51 31 0,000 0,03827063 0,04984425 ! positive regulation of neurogenesis GO:0050769 49 31 0,000 0,03827063 0,0498169 ! positive regulation of T cell differentiation GO:0045582 45 31 0,000 0,03827063 0,04978959 ! positive regulation of multicellular organism growth GO:0040018 42 31 0,000 0,03827063 0,04976231 ! hexose biosynthetic process GO:0019319 37 31 0,000 0,03827063 0,04973506 ! negative regulation of MAP kinase activity GO:0043407 57 31 0,000 0,03827063 0,04970784 ! sterol biosynthetic process GO:0016126 48 31 0,000 0,03827063 0,04968064 ! biogenic amine biosynthetic process GO:0042401 45 31 0,000 0,03827063 0,04965348 ! embryonic epithelial tube formation GO:0001838 50 31 0,000 0,03827063 0,04962635 ! tissue homeostasis GO:0001894 45 31 0,000 0,03827063 0,04959924 GO:0048871|multicellular organismal homeostasis, ! mitotic sister chromatid segregation GO:0000070 47 32 0,000 0,03948145 0,05114055 ! DNA damage checkpoint GO:0000077 57 32 0,000 0,03948145 0,05111265 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 49 32 0,000 0,03948145 0,05108478 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 45 32 0,000 0,03948145 0,05105694 ! negative regulation of protein complex assembly GO:0031333 51 32 0,000 0,03948145 0,05102913 ! regulation of synaptic plasticity GO:0048167 54 32 0,000 0,03948145 0,05100136 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 32 0,000 0,03948145 0,05097361 ! positive regulation of endocytosis GO:0045807 39 32 0,000 0,03948145 0,05094589 ! positive regulation of T cell proliferation GO:0042102 56 32 0,000 0,03948145 0,0509182 ! regulation of striated muscle tissue development GO:0016202 51 32 0,000 0,03948145 0,05089054 ! unsaturated fatty acid biosynthetic process GO:0006636 50 32 0,000 0,03948145 0,05086291 ! regulation of axonogenesis GO:0050770 60 32 0,000 0,03948145 0,05083532 ! telencephalon development GO:0021537 59 32 0,000 0,03948145 0,05080775 ! ovulation cycle GO:0042698 48 32 0,000 0,03948145 0,05078021 ! cofactor catabolic process GO:0051187 52 32 0,000 0,03948145 0,0507527 ! pyridine nucleotide metabolic process GO:0019362 49 32 0,000 0,03948145 0,05072522 ! positive regulation of catabolic process GO:0009896 44 32 0,000 0,03948145 0,05069778 ! placenta development GO:0001890 45 32 0,000 0,03948145 0,05067036 ! symbiosis, encompassing mutualism through parasitism GO:0044403 52 32 0,000 0,03948145 0,05064297 ! vesicle localization GO:0051648 50 32 0,000 0,03948145 0,05061561 ! regulation of muscle development GO:0048634 52 33 0,000 0,04069081 0,05213785 ! mRNA export from nucleus GO:0006406 47 33 0,000 0,04069081 0,05210971 ! negative regulation of secretion GO:0051048 53 33 0,000 0,04069081 0,0520816 ! negative regulation of DNA metabolic process GO:0051053 53 33 0,000 0,04069081 0,05205353 ! glial cell differentiation GO:0010001 65 33 0,000 0,04069081 0,05202548 ! cellular component assembly involved in morphogenesis GO:0010927 52 33 0,000 0,04069081 0,05199746 ! sister chromatid segregation GO:0000819 48 33 0,000 0,04069081 0,05196948 ! sphingoid metabolic process GO:0046519 51 33 0,000 0,04069081 0,05194152 ! maintenance of protein location in cell GO:0032507 66 33 0,000 0,04069081 0,0519136 ! pigment biosynthetic process GO:0046148 55 33 0,000 0,04069081 0,0518857 ! neutral lipid metabolic process GO:0006638 45 33 0,000 0,04069081 0,05185784 GO:0006639|acylglycerol metabolic process, ! erythrocyte differentiation GO:0030218 50 33 0,000 0,04069081 0,05183 ! protein targeting to membrane GO:0006612 63 33 0,000 0,04069081 0,05180219 ! nucleotide catabolic process GO:0009166 47 33 0,000 0,04069081 0,05177442 ! nuclear-transcribed mRNA catabolic process GO:0000956 47 33 0,000 0,04069081 0,05174667 ! leukocyte chemotaxis GO:0030595 48 33 0,000 0,04069081 0,05171896 GO:0060326|cell chemotaxis, ! BMP signaling pathway GO:0030509 49 33 0,000 0,04069081 0,05169127 ! calcium-mediated signaling GO:0019722 54 33 0,000 0,04069081 0,05166361 ! cytokine production GO:0001816 49 33 0,000 0,04069081 0,05163598 ! regulation of microtubule-based process GO:0032886 66 33 0,000 0,04069081 0,05160839 ! RNA modification GO:0009451 43 33 0,000 0,04069081 0,05158082 ! regulation of B cell activation GO:0050864 55 33 0,000 0,04069081 0,05155328 ! positive regulation of immune effector process GO:0002699 53 33 0,000 0,04069081 0,05152577 ! negative regulation of adenylate cyclase activity GO:0007194 56 34 0,000 0,0418987 0,053027 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! ER to Golgi vesicle-mediated transport GO:0006888 57 34 0,000 0,0418987 0,05299873 ! xenobiotic metabolic process GO:0006805 49 34 0,000 0,0418987 0,0529705 ! actomyosin structure organization GO:0031032 48 34 0,000 0,0418987 0,05294229 ! embryonic skeletal system morphogenesis GO:0048704 49 34 0,000 0,0418987 0,05291411 ! monovalent inorganic cation homeostasis GO:0055067 49 34 0,000 0,0418987 0,05288597 ! negative regulation of DNA binding GO:0043392 54 34 0,000 0,0418987 0,05285785 ! positive regulation of cell development GO:0010720 58 34 0,000 0,0418987 0,05282977 ! response to mechanical stimulus GO:0009612 46 34 0,000 0,0418987 0,05280171 ! cell fate specification GO:0001708 49 34 0,000 0,0418987 0,05277368 ! peripheral nervous system development GO:0007422 58 34 0,000 0,0418987 0,05274569 ! isoprenoid metabolic process GO:0006720 47 34 0,000 0,0418987 0,05271772 ! adult locomotory behavior GO:0008344 54 34 0,000 0,0418987 0,05268978 ! monosaccharide biosynthetic process GO:0046364 40 34 0,000 0,0418987 0,05266188 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 47 35 0,000 0,04310514 0,05414954 ! phosphoinositide biosynthetic process GO:0046489 54 35 0,000 0,04310514 0,05412089 ! collagen metabolic process GO:0032963 47 35 0,000 0,04310514 0,05409227 ! cell junction organization GO:0034330 72 35 0,000 0,04310514 0,05406368 ! regulation of ARF protein signal transduction GO:0032012 56 35 0,000 0,04310514 0,05403512 ! metanephros development GO:0001656 61 35 0,000 0,04310514 0,05400659 ! positive regulation of gene-specific transcription GO:0043193 53 35 0,000 0,04310514 0,05397809 ! female gonad development GO:0008585 55 35 0,000 0,04310514 0,05394962 ! lipid homeostasis GO:0055088 63 35 0,000 0,04310514 0,05392119 ! DNA integrity checkpoint GO:0031570 61 35 0,000 0,04310514 0,05389278 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,04310514 0,0538644 ! negative regulation of hydrolase activity GO:0051346 56 35 0,000 0,04310514 0,05383605 ! hindbrain development GO:0030902 56 35 0,000 0,04310514 0,05380773 ! Rho protein signal transduction GO:0007266 53 35 0,000 0,04310514 0,05377944 ! positive regulation of lymphocyte differentiation GO:0045621 51 35 0,000 0,04310514 0,05375118 ! hormone biosynthetic process GO:0042446 49 35 0,000 0,04310514 0,05372295 ! cytokinesis GO:0000910 57 35 0,000 0,04310514 0,05369474 ! embryonic organ development GO:0048568 53 35 0,000 0,04310514 0,05366657 ! pyrimidine nucleotide metabolic process GO:0006220 48 35 0,000 0,04310514 0,05363843 ! negative regulation of cell activation GO:0050866 58 35 0,000 0,04310514 0,05361032 ! protein homooligomerization GO:0051260 59 35 0,000 0,04310514 0,05358224 ! negative regulation of cell adhesion GO:0007162 78 36 0,000 0,04431011 0,05505125 ! regulation of metal ion transport GO:0010959 50 36 0,000 0,04431011 0,05502245 ! regulation of intracellular protein transport GO:0033157 64 36 0,000 0,04431011 0,05499367 ! development of primary male sexual characteristics GO:0046546 52 36 0,000 0,04431011 0,05496492 ! spliceosome assembly GO:0000245 65 36 0,000 0,04431011 0,0549362 ! mismatch repair GO:0006298 42 36 0,000 0,04431011 0,05490752 ! regulation of action potential in neuron GO:0019228 60 36 0,000 0,04431011 0,05487886 ! glycerol ether metabolic process GO:0006662 49 36 0,000 0,04431011 0,05485023 ! regulation of proteolysis GO:0030162 53 36 0,000 0,04431011 0,05482163 ! energy coupled proton transport, down electrochemical gradient GO:0015985 55 36 0,000 0,04431011 0,05479307 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 53 36 0,000 0,04431011 0,05476453 ! dorsal/ventral pattern formation GO:0009953 50 36 0,000 0,04431011 0,05473602 ! eye morphogenesis GO:0048592 64 36 0,000 0,04431011 0,05470754 ! cellular response to insulin stimulus GO:0032869 60 36 0,000 0,04431011 0,05467909 ! regulation of smooth muscle cell proliferation GO:0048660 60 37 0,000 0,04551363 0,05613505 ! positive regulation of DNA metabolic process GO:0051054 64 37 0,000 0,04551363 0,05610589 ! mammary gland development GO:0030879 73 37 0,000 0,04551363 0,05607676 ! positive regulation of JAK-STAT cascade GO:0046427 49 37 0,000 0,04551363 0,05604766 ! ear morphogenesis GO:0042471 50 37 0,000 0,04551363 0,05601859 ! odontogenesis GO:0042476 60 37 0,000 0,04551363 0,05598955 ! negative regulation of binding GO:0051100 59 37 0,000 0,04551363 0,05596054 ! mitotic cell cycle checkpoint GO:0007093 74 37 0,000 0,04551363 0,05593156 ! tissue remodeling GO:0048771 65 37 0,000 0,04551363 0,05590261 ! carbohydrate homeostasis GO:0033500 45 37 0,000 0,04551363 0,05587369 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 58 37 0,000 0,04551363 0,0558448 ! keratinocyte differentiation GO:0030216 55 37 0,000 0,04551363 0,05581594 ! natural killer cell activation GO:0030101 45 37 0,000 0,04551363 0,05578711 ! polyol metabolic process GO:0019751 47 37 0,000 0,04551363 0,05575831 ! androgen receptor signaling pathway GO:0030521 66 37 0,000 0,04551363 0,05572954 ! glucan metabolic process GO:0044042 54 37 0,000 0,04551363 0,0557008 GO:0006073|cellular glucan metabolic process, ! positive regulation of transcription factor activity GO:0051091 57 38 0,000 0,04671569 0,05714244 GO:0090047|positive regulation of transcription regulator activity, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 48 38 0,000 0,04671569 0,057113 GO:0006956|complement activation, ! regulation of hormone secretion GO:0046883 54 38 0,000 0,04671569 0,05708359 ! regulation of neuron projection development GO:0010975 73 38 0,000 0,04671569 0,05705422 ! feeding behavior GO:0007631 50 38 0,000 0,04671569 0,05702487 ! organic ether metabolic process GO:0018904 51 38 0,000 0,04671569 0,05699555 ! antigen processing and presentation of peptide antigen GO:0048002 67 38 0,000 0,04671569 0,05696626 ! development of primary female sexual characteristics GO:0046545 59 38 0,000 0,04671569 0,056937 GO:0046660|female sex differentiation, ! regulation of Rab protein signal transduction GO:0032483 58 38 0,000 0,04671569 0,05690777 GO:0032313|regulation of Rab GTPase activity, ! multicellular organismal macromolecule metabolic process GO:0044259 51 38 0,000 0,04671569 0,05687857 ! ion transmembrane transport GO:0034220 58 38 0,000 0,04671569 0,05684941 ! heterocycle biosynthetic process GO:0018130 49 38 0,000 0,04671569 0,05682027 ! ribonucleoside metabolic process GO:0009119 51 38 0,000 0,04671569 0,05679116 ! neuron migration GO:0001764 59 38 0,000 0,04671569 0,05676208 ! maintenance of protein location GO:0045185 72 38 0,000 0,04671569 0,05673303 ! pigment metabolic process GO:0042440 66 38 0,000 0,04671569 0,05670401 ! regulation of cell morphogenesis involved in differentiation GO:0010769 72 38 0,000 0,04671569 0,05667502 ! mRNA catabolic process GO:0006402 58 39 0,000 0,0479163 0,05810188 ! response to reactive oxygen species GO:0000302 64 39 0,000 0,0479163 0,05807221 ! establishment or maintenance of cell polarity GO:0007163 74 39 0,000 0,0479163 0,05804257 ! striated muscle cell differentiation GO:0051146 58 39 0,000 0,0479163 0,05801295 ! neural tube development GO:0021915 58 39 0,000 0,0479163 0,05798337 ! polysaccharide biosynthetic process GO:0000271 51 39 0,000 0,0479163 0,05795382 ! regulation of protein stability GO:0031647 58 39 0,000 0,0479163 0,05792429 ! female gamete generation GO:0007292 50 39 0,000 0,0479163 0,0578948 ! aerobic respiration GO:0009060 56 39 0,000 0,0479163 0,05786534 ! positive regulation of leukocyte proliferation GO:0070665 64 39 0,000 0,0479163 0,0578359 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! response to xenobiotic stimulus GO:0009410 55 39 0,000 0,0479163 0,0578065 ! protein amino acid N-linked glycosylation GO:0006487 57 40 0,000 0,04911546 0,05922306 ! Notch signaling pathway GO:0007219 64 40 0,000 0,04911546 0,05919299 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 68 40 0,000 0,04911546 0,05916294 ! monocarboxylic acid transport GO:0015718 68 40 0,000 0,04911546 0,05913292 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 71 40 0,000 0,04911546 0,05910294 ! hormone-mediated signaling GO:0009755 57 40 0,000 0,04911546 0,05907298 ! alcohol biosynthetic process GO:0046165 48 40 0,000 0,04911546 0,05904305 ! phagocytosis GO:0006909 65 40 0,000 0,04911546 0,05901316 ! mesenchymal cell development GO:0014031 70 40 0,000 0,04911546 0,05898329 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! erythrocyte homeostasis GO:0034101 60 40 0,000 0,04911546 0,05895346 ! B cell differentiation GO:0030183 70 40 0,000 0,04911546 0,05892366 ! pigmentation GO:0043473 81 40 0,000 0,04911546 0,05889388 ! developmental growth GO:0048589 70 40 0,000 0,04911546 0,05886414 ! synapse organization GO:0050808 61 40 0,000 0,04911546 0,05883442 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 61 41 0,000 0,05031317 0,06023872 ! RNA export from nucleus GO:0006405 57 41 0,000 0,05031317 0,06020835 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 72 41 0,000 0,05031317 0,060178 ! detection of stimulus involved in sensory perception GO:0050906 55 41 0,000 0,05031317 0,06014768 ! regulation of epithelial cell proliferation GO:0050678 80 41 0,000 0,05031317 0,0601174 ! ATP synthesis coupled electron transport GO:0042773 50 41 0,000 0,05031317 0,06008714 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of protein secretion GO:0050708 55 41 0,000 0,05031317 0,06005692 ! cell growth GO:0016049 71 41 0,000 0,05031317 0,06002672 ! maintenance of location in cell GO:0051651 77 41 0,000 0,05031317 0,05999656 ! transforming growth factor beta receptor signaling pathway GO:0007179 59 42 0,000 0,05150943 0,0613922 ! regulation of nucleocytoplasmic transport GO:0046822 75 42 0,000 0,05150943 0,06136138 ! learning GO:0007612 75 42 0,000 0,05150943 0,0613306 ! negative regulation of protein complex disassembly GO:0043242 78 42 0,000 0,05150943 0,06129984 ! cellular amide metabolic process GO:0043603 63 42 0,000 0,05150943 0,06126911 ! morphogenesis of embryonic epithelium GO:0016331 69 42 0,000 0,05150943 0,06123842 ! gliogenesis GO:0042063 85 42 0,000 0,05150943 0,06120775 ! induction of apoptosis by intracellular signals GO:0008629 78 42 0,000 0,05150943 0,06117712 ! male sex differentiation GO:0046661 62 42 0,000 0,05150943 0,06114651 ! double-strand break repair GO:0006302 75 42 0,000 0,05150943 0,06111594 ! epidermal cell differentiation GO:0009913 61 42 0,000 0,05150943 0,0610854 ! regulation of myeloid cell differentiation GO:0045637 78 42 0,000 0,05150943 0,06105488 ! oxidoreduction coenzyme metabolic process GO:0006733 62 42 0,000 0,05150943 0,0610244 ! mitochondrial transport GO:0006839 66 43 0,000 0,05270424 0,06240877 ! protein amino acid lipidation GO:0006497 69 43 0,000 0,05270424 0,06237764 ! energy reserve metabolic process GO:0006112 67 43 0,000 0,05270424 0,06234654 ! regulation of tube size GO:0035150 69 43 0,000 0,05270424 0,06231548 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 78 43 0,000 0,05270424 0,06228445 ! regulation of T cell proliferation GO:0042129 72 43 0,000 0,05270424 0,06225344 ! positive regulation of DNA binding GO:0043388 65 43 0,000 0,05270424 0,06222247 ! T cell differentiation GO:0030217 78 43 0,000 0,05270424 0,06219153 ! icosanoid metabolic process GO:0006690 65 43 0,000 0,05270424 0,06216062 ! amino acid activation GO:0043038 61 43 0,000 0,05270424 0,06212974 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of protein transport GO:0051222 59 43 0,000 0,05270424 0,06209889 ! epithelial cell differentiation GO:0030855 64 44 0,000 0,05389761 0,06347346 ! receptor-mediated endocytosis GO:0006898 85 44 0,000 0,05389761 0,06344198 ! cellular component disassembly GO:0022411 66 44 0,000 0,05389761 0,06341053 ! cytoskeleton-dependent intracellular transport GO:0030705 78 44 0,000 0,05389761 0,0633791 ! peptide metabolic process GO:0006518 64 44 0,000 0,05389761 0,06334771 ! multicellular organismal metabolic process GO:0044236 57 44 0,000 0,05389761 0,06331635 ! inner ear development GO:0048839 66 44 0,000 0,05389761 0,06328502 ! regulation of lymphocyte mediated immunity GO:0002706 77 44 0,000 0,05389761 0,06325372 ! regulation of gene expression, epigenetic GO:0040029 86 44 0,000 0,05389761 0,06322246 ! chromatin remodeling GO:0006338 73 44 0,000 0,05389761 0,06319122 ! biopolymer methylation GO:0043414 67 44 0,000 0,05389761 0,06316002 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 58 44 0,000 0,05389761 0,06312884 ! JNK cascade GO:0007254 66 44 0,000 0,05389761 0,0630977 ! JAK-STAT cascade GO:0007259 62 44 0,000 0,05389761 0,06306658 ! regulation of cell shape GO:0008360 83 44 0,000 0,05389761 0,0630355 ! activation of adenylate cyclase activity GO:0007190 79 45 0,000 0,05508954 0,06439777 ! positive regulation of binding GO:0051099 67 45 0,000 0,05508954 0,06436606 ! stress-activated protein kinase signaling pathway GO:0031098 69 45 0,000 0,05508954 0,06433438 ! regulation of ion transport GO:0043269 60 45 0,000 0,05508954 0,06430274 ! glucose transport GO:0015758 60 45 0,000 0,05508954 0,06427113 ! neuromuscular process GO:0050905 89 45 0,000 0,05508954 0,06423954 ! positive regulation of cytokine biosynthetic process GO:0042108 61 45 0,000 0,05508954 0,06420799 ! glycosaminoglycan metabolic process GO:0030203 68 45 0,000 0,05508954 0,06417647 ! regulation of T cell differentiation GO:0045580 68 45 0,000 0,05508954 0,06414498 ! response to insulin stimulus GO:0032868 71 45 0,000 0,05508954 0,06411352 ! regulation of actin filament polymerization GO:0030833 71 46 0,000 0,05628002 0,06546691 ! regulation of translational initiation GO:0006446 70 46 0,000 0,05628002 0,06543483 ! regulation of action potential GO:0001508 80 46 0,000 0,05628002 0,06540278 ! hexose transport GO:0008645 62 46 0,000 0,05628002 0,06537077 GO:0015749|monosaccharide transport, ! activation of caspase activity GO:0006919 70 46 0,000 0,05628002 0,06533879 ! excretion GO:0007588 72 46 0,000 0,05628002 0,06530684 ! regulation of leukocyte mediated immunity GO:0002703 80 46 0,000 0,05628002 0,06527492 ! regulation of inflammatory response GO:0050727 74 46 0,000 0,05628002 0,06524303 ! epithelial tube morphogenesis GO:0060562 73 46 0,000 0,05628002 0,06521118 ! positive regulation of defense response GO:0031349 70 47 0,000 0,05746906 0,06655641 ! branching morphogenesis of a tube GO:0048754 85 47 0,000 0,05746906 0,06652394 ! embryonic skeletal system development GO:0048706 65 47 0,000 0,05746906 0,06649151 ! unsaturated fatty acid metabolic process GO:0033559 71 47 0,000 0,05746906 0,06645911 ! lipoprotein biosynthetic process GO:0042158 74 47 0,000 0,05746906 0,06642673 ! regulation of JNK cascade GO:0046328 72 47 0,000 0,05746906 0,06639439 ! positive regulation of adenylate cyclase activity GO:0045762 90 48 0,000 0,05865667 0,06773347 ! viral infectious cycle GO:0019058 80 48 0,000 0,05865667 0,06770052 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 75 48 0,000 0,05865667 0,06766761 ! leukocyte migration GO:0050900 76 48 0,000 0,05865667 0,06763473 ! cellular amino acid biosynthetic process GO:0008652 60 48 0,000 0,05865667 0,06760188 ! striated muscle contraction GO:0006941 78 48 0,000 0,05865667 0,06756906 ! vascular process in circulatory system GO:0003018 78 48 0,000 0,05865667 0,06753628 ! DNA-dependent DNA replication GO:0006261 73 48 0,000 0,05865667 0,06750353 ! tRNA processing GO:0008033 56 48 0,000 0,05865667 0,06747081 ! cell maturation GO:0048469 69 48 0,000 0,05865667 0,06743812 ! detection of abiotic stimulus GO:0009582 66 48 0,000 0,05865667 0,06740546 ! vesicle organization GO:0016050 87 48 0,000 0,05865667 0,06737283 ! regulation of neuron apoptosis GO:0043523 84 48 0,000 0,05865667 0,06734024 ! respiratory electron transport chain GO:0022904 63 49 0,000 0,05984284 0,06866879 ! regulation of cell projection organization GO:0031344 95 49 0,000 0,05984284 0,0686356 ! glycolysis GO:0006096 63 49 0,000 0,05984284 0,06860244 ! regulation of gene-specific transcription GO:0032583 78 49 0,000 0,05984284 0,06856932 ! regulation of protein complex disassembly GO:0043244 88 49 0,000 0,05984284 0,06853622 ! induction of apoptosis by extracellular signals GO:0008624 96 49 0,000 0,05984284 0,06850316 ! response to temperature stimulus GO:0009266 66 49 0,000 0,05984284 0,06847013 ! endocrine system development GO:0035270 86 49 0,000 0,05984284 0,06843713 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,05984284 0,06840417 ! generation of a signal involved in cell-cell signaling GO:0003001 74 49 0,000 0,05984284 0,06837123 ! gastrulation GO:0007369 80 49 0,000 0,05984284 0,06833833 ! RNA elongation from RNA polymerase II promoter GO:0006368 65 49 0,000 0,05984284 0,06830546 ! positive regulation of cyclase activity GO:0031281 91 49 0,000 0,05984284 0,06827262 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 84 49 0,000 0,05984284 0,06823981 ! regulation of intracellular transport GO:0032386 83 49 0,000 0,05984284 0,06820704 ! methylation GO:0032259 74 49 0,000 0,05984284 0,06817429 ! cell redox homeostasis GO:0045454 72 50 0,000 0,06102757 0,06949061 ! negative regulation of cell migration GO:0030336 105 50 0,000 0,06102757 0,06945728 ! regulation of muscle contraction GO:0006937 75 50 0,000 0,06102757 0,06942398 ! cellular polysaccharide metabolic process GO:0044264 70 50 0,000 0,06102757 0,06939072 ! histone modification GO:0016570 81 50 0,000 0,06102757 0,06935748 ! positive regulation of lyase activity GO:0051349 92 50 0,000 0,06102757 0,06932428 ! heterocycle catabolic process GO:0046700 74 50 0,000 0,06102757 0,06929111 ! regulation of mast cell proliferation GO:0070666 80 50 0,000 0,06102757 0,06925797 ! RNA catabolic process GO:0006401 77 51 0,000 0,06221087 0,07056711 ! chloride transport GO:0006821 78 51 0,000 0,06221087 0,0705334 ! positive regulation of caspase activity GO:0043280 77 51 0,000 0,06221087 0,07049971 GO:0010952|positive regulation of peptidase activity, ! membrane fusion GO:0006944 82 51 0,000 0,06221087 0,07046606 ! regulation of ossification GO:0030278 82 51 0,000 0,06221087 0,07043244 ! heart morphogenesis GO:0003007 71 51 0,000 0,06221087 0,07039885 ! RNA elongation GO:0006354 67 51 0,000 0,06221087 0,0703653 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 74 51 0,000 0,06221087 0,07033178 ! aminoglycan metabolic process GO:0006022 77 52 0,000 0,06339274 0,0716338 ! activation of phospholipase C activity GO:0007202 93 52 0,000 0,06339274 0,0715997 GO:0010863|positive regulation of phospholipase C activity, ! skeletal muscle fiber development GO:0048741 79 52 0,000 0,06339274 0,07156564 ! regulation of DNA replication GO:0006275 88 52 0,000 0,06339274 0,07153161 ! immunoglobulin mediated immune response GO:0016064 72 52 0,000 0,06339274 0,07149761 GO:0019724|B cell mediated immunity, ! cell recognition GO:0008037 78 52 0,000 0,06339274 0,07146364 ! covalent chromatin modification GO:0016569 90 52 0,000 0,06339274 0,07142971 ! regulation of adaptive immune response GO:0002819 90 52 0,000 0,06339274 0,07139581 ! proton transport GO:0015992 78 52 0,000 0,06339274 0,07136194 ! negative regulation of immune system process GO:0002683 90 52 0,000 0,06339274 0,0713281 ! protein amino acid autophosphorylation GO:0046777 97 52 0,000 0,06339274 0,0712943 ! transition metal ion transport GO:0000041 88 53 0,000 0,06457318 0,07258747 ! regulation of angiogenesis GO:0045765 105 53 0,000 0,06457318 0,0725531 ! muscle fiber development GO:0048747 80 53 0,000 0,06457318 0,07251877 ! sulfur compound biosynthetic process GO:0044272 71 53 0,000 0,06457318 0,07248446 ! positive regulation of phospholipase activity GO:0010518 94 53 0,000 0,06457318 0,07245019 ! regulation of multicellular organism growth GO:0040014 72 53 0,000 0,06457318 0,07241595 ! regulation of endocytosis GO:0030100 71 53 0,000 0,06457318 0,07238174 ! regulation of lymphocyte differentiation GO:0045619 84 53 0,000 0,06457318 0,07234757 ! glutamine family amino acid metabolic process GO:0009064 71 53 0,000 0,06457318 0,07231343 ! cellular amino acid derivative biosynthetic process GO:0042398 73 53 0,000 0,06457318 0,07227932 ! regulation of leukocyte proliferation GO:0070663 88 53 0,000 0,06457318 0,07224524 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! maintenance of location GO:0051235 94 53 0,000 0,06457318 0,07221119 ! hydrogen transport GO:0006818 81 54 0,000 0,06575219 0,07349503 ! response to estrogen stimulus GO:0043627 88 54 0,000 0,06575219 0,07346043 ! regulation of mitosis GO:0007088 91 54 0,000 0,06575219 0,07342586 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 100 54 0,000 0,06575219 0,07339132 ! negative regulation of cytoskeleton organization GO:0051494 96 54 0,000 0,06575219 0,07335681 ! regulation of actin polymerization or depolymerization GO:0008064 81 54 0,000 0,06575219 0,07332234 ! nucleotide-excision repair GO:0006289 70 54 0,000 0,06575219 0,0732879 ! sphingolipid metabolic process GO:0006665 80 54 0,000 0,06575219 0,07325349 ! ribonucleoprotein complex assembly GO:0022618 90 54 0,000 0,06575219 0,07321912 ! morphogenesis of a branching structure GO:0001763 99 54 0,000 0,06575219 0,07318478 ! germ cell development GO:0007281 82 54 0,000 0,06575219 0,07315047 ! positive regulation of cytokine production GO:0001819 83 54 0,000 0,06575219 0,07311619 ! regulation of protein polymerization GO:0032271 84 54 0,000 0,06575219 0,07308194 ! establishment of organelle localization GO:0051656 91 54 0,000 0,06575219 0,07304773 ! glycerophospholipid biosynthetic process GO:0046474 82 55 0,000 0,06692977 0,07432117 ! ear development GO:0043583 83 55 0,000 0,06692977 0,07428641 ! regulation of phospholipase activity GO:0010517 96 55 0,000 0,06692977 0,07425168 ! integrin-mediated signaling pathway GO:0007229 93 55 0,000 0,06692977 0,07421699 ! positive regulation of lipase activity GO:0060193 96 55 0,000 0,06692977 0,07418232 ! regulation of actin filament length GO:0030832 88 56 0,000 0,06810593 0,07545069 ! positive regulation of secretion GO:0051047 83 56 0,000 0,06810593 0,07541548 ! nucleoside metabolic process GO:0009116 74 56 0,000 0,06810593 0,0753803 ! DNA catabolic process GO:0006308 71 56 0,000 0,06810593 0,07534516 ! positive regulation of organelle organization GO:0010638 95 56 0,000 0,06810593 0,07531005 ! adult behavior GO:0030534 90 56 0,000 0,06810593 0,07527498 ! cartilage development GO:0051216 84 56 0,000 0,06810593 0,07523993 ! regulation of neurotransmitter levels GO:0001505 85 57 0,000 0,06928067 0,0765021 ! mesoderm development GO:0007498 84 57 0,000 0,06928067 0,07646652 ! aging GO:0007568 91 57 0,000 0,06928067 0,07643097 ! nuclear export GO:0051168 85 57 0,000 0,06928067 0,07639546 ! cellular amino acid catabolic process GO:0009063 82 57 0,000 0,06928067 0,07635997 ! single fertilization GO:0007338 67 57 0,000 0,06928067 0,07632452 ! regulation of cellular component size GO:0032535 90 58 0,000 0,07045398 0,07758111 ! lipid modification GO:0030258 82 58 0,000 0,07045398 0,07754513 ! positive regulation of growth GO:0045927 78 58 0,000 0,07045398 0,07750918 ! DNA damage response, signal transduction GO:0042770 105 58 0,000 0,07045398 0,07747326 ! membrane lipid metabolic process GO:0006643 88 58 0,000 0,07045398 0,07743738 ! negative regulation of cell motion GO:0051271 118 58 0,000 0,07045398 0,07740152 ! regulation of bone remodeling GO:0046850 102 59 0,000 0,07162587 0,07865257 ! viral reproductive process GO:0022415 99 59 0,000 0,07162587 0,07861619 ! skeletal system morphogenesis GO:0048705 90 59 0,000 0,07162587 0,07857984 ! chromosome segregation GO:0007059 93 59 0,000 0,07162587 0,07854353 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,07162587 0,07850725 ! negative regulation of response to stimulus GO:0048585 88 59 0,000 0,07162587 0,07847101 ! cell projection assembly GO:0030031 90 59 0,000 0,07162587 0,07843479 ! glucose catabolic process GO:0006007 78 60 0,000 0,07279635 0,07967977 ! regulation of lipid metabolic process GO:0019216 93 60 0,000 0,07279635 0,07964303 ! water-soluble vitamin metabolic process GO:0006767 84 60 0,000 0,07279635 0,07960633 ! response to peptide hormone stimulus GO:0043434 97 60 0,000 0,07279635 0,07956966 ! kidney development GO:0001822 101 60 0,000 0,07279635 0,07953303 ! positive regulation of cell motion GO:0051272 110 60 0,000 0,07279635 0,07949643 ! regulation of protein complex assembly GO:0043254 95 61 0,000 0,07396541 0,08073593 ! carbohydrate transport GO:0008643 83 61 0,000 0,07396541 0,08069881 ! protein maturation by peptide bond cleavage GO:0051605 86 61 0,000 0,07396541 0,08066172 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 98 62 0,000 0,07513305 0,08189744 ! amino acid transport GO:0006865 97 62 0,000 0,07513305 0,08185984 ! negative regulation of protein kinase activity GO:0006469 110 62 0,000 0,07513305 0,08182227 ! activation of MAPK activity GO:0000187 95 62 0,000 0,07513305 0,08178474 ! multicellular organism reproduction GO:0032504 98 62 0,000 0,07513305 0,08174724 GO:0048609|reproductive process in a multicellular organism, ! lipoprotein metabolic process GO:0042157 96 62 0,000 0,07513305 0,08170977 ! glycerolipid biosynthetic process GO:0045017 92 62 0,000 0,07513305 0,08167234 ! detection of external stimulus GO:0009581 78 62 0,000 0,07513305 0,08163495 ! regulation of tissue remodeling GO:0034103 113 62 0,000 0,07513305 0,08159759 ! secondary metabolic process GO:0019748 95 62 0,000 0,07513305 0,08156026 ! gonad development GO:0008406 91 62 0,000 0,07513305 0,08152297 ! exocytosis GO:0006887 91 63 0,000 0,07629928 0,08275054 ! negative regulation of kinase activity GO:0033673 112 63 0,000 0,07629928 0,08271274 ! oxygen and reactive oxygen species metabolic process GO:0006800 89 63 0,000 0,07629928 0,08267497 ! embryonic limb morphogenesis GO:0030326 96 63 0,000 0,07629928 0,08263724 GO:0035113|embryonic appendage morphogenesis, ! coenzyme biosynthetic process GO:0009108 81 63 0,000 0,07629928 0,08259954 ! regulation of heart contraction GO:0008016 104 63 0,000 0,07629928 0,08256188 ! developmental maturation GO:0021700 90 63 0,000 0,07629928 0,08252424 ! actin filament organization GO:0007015 107 64 0,000 0,0774641 0,08374592 ! fertilization GO:0009566 79 64 0,000 0,0774641 0,08370779 ! viral reproduction GO:0016032 104 64 0,000 0,0774641 0,08366969 ! myeloid cell differentiation GO:0030099 101 64 0,000 0,0774641 0,08363162 ! amine catabolic process GO:0009310 100 65 0,000 0,07862751 0,08484906 ! negative regulation of cell growth GO:0030308 123 65 0,000 0,07862751 0,08481049 ! camera-type eye development GO:0043010 103 65 0,000 0,07862751 0,08477195 ! steroid hormone receptor signaling pathway GO:0030518 116 65 0,000 0,07862751 0,08473346 ! regulation of lipase activity GO:0060191 117 65 0,000 0,07862751 0,08469499 ! regulation of homeostatic process GO:0032844 122 65 0,000 0,07862751 0,08465657 ! organelle localization GO:0051640 105 65 0,000 0,07862751 0,08461817 ! regulation of transcription factor activity GO:0051090 109 66 0,000 0,07978951 0,08582978 GO:0090046|regulation of transcription regulator activity, ! cellular hormone metabolic process GO:0034754 95 66 0,000 0,07978951 0,08579089 ! sensory perception of smell GO:0007608 81 66 0,000 0,07978951 0,08575204 ! regulation of cytokine biosynthetic process GO:0042035 91 66 0,000 0,07978951 0,08571322 ! cAMP-mediated signaling GO:0019933 109 66 0,000 0,07978951 0,08567443 ! lung development GO:0030324 112 66 0,000 0,07978951 0,08563568 ! lymphocyte mediated immunity GO:0002449 95 66 0,000 0,07978951 0,08559697 ! B cell activation GO:0042113 119 66 0,000 0,07978951 0,08555829 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 97 66 0,000 0,07978951 0,08551965 ! negative regulation of transferase activity GO:0051348 117 66 0,000 0,07978951 0,08548104 ! protein oligomerization GO:0051259 109 66 0,000 0,07978951 0,08544246 ! cell cycle checkpoint GO:0000075 123 67 0,000 0,0809501 0,08664618 ! negative regulation of cell size GO:0045792 125 67 0,000 0,0809501 0,08660712 ! neurotransmitter transport GO:0006836 92 67 0,000 0,0809501 0,08656809 ! regulation of cellular response to stress GO:0080135 100 67 0,000 0,0809501 0,08652909 ! appendage morphogenesis GO:0035107 103 67 0,000 0,0809501 0,08649013 GO:0035108|limb morphogenesis, ! fatty acid biosynthetic process GO:0006633 107 67 0,000 0,0809501 0,08645121 ! extracellular matrix organization GO:0030198 117 67 0,000 0,0809501 0,08641232 ! negative regulation of ligase activity GO:0051352 100 67 0,000 0,0809501 0,08637346 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of caspase activity GO:0043281 104 68 0,000 0,08210928 0,08757094 ! phosphoinositide metabolic process GO:0030384 100 68 0,000 0,08210928 0,0875316 ! defense response to bacterium GO:0042742 79 68 0,000 0,08210928 0,08749229 ! regulation of vesicle-mediated transport GO:0060627 98 68 0,000 0,08210928 0,08745302 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 109 68 0,000 0,08210928 0,08741379 ! activation of immune response GO:0002253 93 68 0,000 0,08210928 0,08737459 ! appendage development GO:0048736 108 69 0,000 0,08326707 0,0885669 GO:0060173|limb development, ! respiratory tube development GO:0030323 117 69 0,000 0,08326707 0,08852722 ! urogenital system development GO:0001655 114 69 0,000 0,08326707 0,08848757 ! regulation of endopeptidase activity GO:0052548 106 70 0,000 0,08442345 0,0896763 ! hexose catabolic process GO:0019320 95 70 0,000 0,08442345 0,08963617 ! adaptive immune response GO:0002250 102 70 0,000 0,08442345 0,08959609 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 104 71 0,000 0,08557843 0,09078123 ! cell-matrix adhesion GO:0007160 133 71 0,000 0,08557843 0,09074067 ! elevation of cytosolic calcium ion concentration GO:0007204 126 71 0,000 0,08557843 0,09070014 ! axon guidance GO:0007411 116 71 0,000 0,08557843 0,09065965 ! intracellular receptor-mediated signaling pathway GO:0030522 124 71 0,000 0,08557843 0,0906192 ! regulation of actin cytoskeleton organization GO:0032956 120 72 0,000 0,08673201 0,09179976 ! response to drug GO:0042493 115 72 0,000 0,08673201 0,09175884 ! cytosolic calcium ion homeostasis GO:0051480 128 72 0,000 0,08673201 0,09171794 ! positive regulation of T cell activation GO:0050870 117 72 0,000 0,08673201 0,09167709 ! respiratory system development GO:0060541 123 72 0,000 0,08673201 0,09163627 ! rhythmic process GO:0048511 113 72 0,000 0,08673201 0,09159549 ! regulation of immune effector process GO:0002697 121 72 0,000 0,08673201 0,09155475 ! learning or memory GO:0007611 132 73 0,000 0,0878842 0,09272975 ! humoral immune response GO:0006959 93 73 0,000 0,0878842 0,09268853 ! regulation of MAPKKK cascade GO:0043408 123 73 0,000 0,0878842 0,09264736 ! acute inflammatory response GO:0002526 107 74 0,000 0,08903499 0,09381884 ! activation of protein kinase activity GO:0032147 115 74 0,000 0,08903499 0,0937772 ! regulation of actin filament-based process GO:0032970 122 74 0,000 0,08903499 0,09373559 ! development of primary sexual characteristics GO:0045137 107 74 0,000 0,08903499 0,09369402 ! transcription initiation from RNA polymerase II promoter GO:0006367 100 74 0,000 0,08903499 0,09365249 ! regulation of neuron differentiation GO:0045664 130 74 0,000 0,08903499 0,093611 ! regulation of Rho protein signal transduction GO:0035023 126 74 0,000 0,08903499 0,09356954 ! regulation of synaptic transmission GO:0050804 117 74 0,000 0,08903499 0,09352812 ! leukocyte mediated immunity GO:0002443 107 75 0,000 0,09018438 0,0946936 ! regulation of peptidase activity GO:0052547 113 75 0,000 0,09018438 0,09465172 ! inorganic anion transport GO:0015698 109 75 0,000 0,09018438 0,09460988 ! lymphocyte differentiation GO:0030098 135 75 0,000 0,09018438 0,09456807 ! phospholipid biosynthetic process GO:0008654 109 76 0,000 0,09133239 0,09572957 ! cell-substrate adhesion GO:0031589 141 76 0,000 0,09133239 0,09568731 ! regulation of Ras GTPase activity GO:0032318 125 76 0,000 0,09133239 0,09564508 ! negative regulation of transport GO:0051051 122 77 0,000 0,092479 0,09680312 ! cellular lipid catabolic process GO:0044242 117 77 0,000 0,092479 0,09676043 ! response to nutrient GO:0007584 114 77 0,000 0,092479 0,09671779 ! monosaccharide catabolic process GO:0046365 104 77 0,000 0,092479 0,09667518 ! regulation of blood pressure GO:0008217 119 78 0,000 0,09362422 0,09782927 ! muscle cell differentiation GO:0042692 117 78 0,000 0,09362422 0,09778622 ! mitochondrion organization GO:0007005 127 78 0,000 0,09362422 0,09774319 ! negative regulation of growth GO:0045926 140 78 0,000 0,09362422 0,09770021 ! amine transport GO:0015837 115 78 0,000 0,09362422 0,09765727 ! antigen processing and presentation GO:0019882 114 78 0,000 0,09362422 0,09761436 ! steroid biosynthetic process GO:0006694 111 79 0,000 0,09476806 0,09876355 ! regulation of adenylate cyclase activity GO:0045761 143 80 0,000 0,09591051 0,09991029 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 123 80 0,000 0,09591051 0,09986645 ! regulation of DNA binding GO:0051101 130 80 0,000 0,09591051 0,09982265 ! tube morphogenesis GO:0035239 140 80 0,000 0,09591051 0,09977889 ! eye development GO:0001654 130 80 0,000 0,09591051 0,09973516 ! intracellular protein transmembrane transport GO:0065002 115 80 0,000 0,09591051 0,09969148 ! protein ubiquitination GO:0016567 135 80 0,000 0,09591051 0,09964783 ! negative regulation of organelle organization GO:0010639 136 80 0,000 0,09591051 0,09960422 ! regulation of transmission of nerve impulse GO:0051969 126 80 0,000 0,09591051 0,09956065 ! response to steroid hormone stimulus GO:0048545 129 80 0,000 0,09591051 0,09951711 ! cellular response to hormone stimulus GO:0032870 125 80 0,000 0,09591051 0,09947362 ! blood coagulation GO:0007596 129 81 0,000 0,09705158 0,1006131 GO:0050817|coagulation, ! amine biosynthetic process GO:0009309 108 81 0,000 0,09705158 0,10056917 ! oxidative phosphorylation GO:0006119 110 81 0,000 0,09705158 0,10052527 ! nitrogen compound catabolic process GO:0044270 125 81 0,000 0,09705158 0,10048141 ! response to hypoxia GO:0001666 155 81 0,000 0,09705158 0,10043759 ! regulation of protein transport GO:0051223 123 81 0,000 0,09705158 0,10039381 GO:0070201|regulation of establishment of protein localization, ! regulation of cAMP biosynthetic process GO:0030817 148 82 0,000 0,09819126 0,10152848 ! neuropeptide signaling pathway GO:0007218 101 82 0,000 0,09819126 0,10148426 ! regulation of cell morphogenesis GO:0022604 155 82 0,000 0,09819126 0,10144008 ! regulation of cyclase activity GO:0031279 146 82 0,000 0,09819126 0,10139593 ! cholesterol metabolic process GO:0008203 120 83 0,000 0,09932956 0,10252677 ! response to oxygen levels GO:0070482 160 83 0,000 0,09932956 0,1024822 ! regulation of cell cycle process GO:0010564 139 83 0,000 0,09932956 0,10243766 ! regulation of lyase activity GO:0051339 147 83 0,000 0,09932956 0,10239316 ! cofactor biosynthetic process GO:0051188 108 83 0,000 0,09932956 0,1023487 ! positive regulation of lymphocyte activation GO:0051251 134 83 0,000 0,09932956 0,10230427 ! regulation of cAMP metabolic process GO:0030814 153 84 0,000 0,10046648 0,10343035 ! digestion GO:0007586 111 84 0,000 0,10046648 0,1033855 ! regulation of neurological system process GO:0031644 133 84 0,000 0,10046648 0,10334069 ! ATP biosynthetic process GO:0006754 131 84 0,000 0,10046648 0,10329591 ! cellular respiration GO:0045333 119 85 0,000 0,10160203 0,1044182 ! biogenic amine metabolic process GO:0006576 128 85 0,000 0,10160203 0,10437299 ! T cell activation GO:0042110 154 85 0,000 0,10160203 0,10432783 ! sex differentiation GO:0007548 126 85 0,000 0,10160203 0,10428271 ! protein import into nucleus GO:0006606 145 85 0,000 0,10160203 0,10423762 ! one-carbon metabolic process GO:0006730 126 85 0,000 0,10160203 0,10419257 ! alcohol catabolic process GO:0046164 119 86 0,000 0,1027362 0,10531015 ! carbohydrate biosynthetic process GO:0016051 111 86 0,000 0,1027362 0,10526468 ! regulation of nucleotide biosynthetic process GO:0030808 155 87 0,000 0,10386899 0,10637942 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! hemostasis GO:0007599 138 87 0,000 0,10386899 0,10633353 ! regulation of defense response GO:0031347 135 87 0,000 0,10386899 0,10628768 ! tRNA metabolic process GO:0006399 110 87 0,000 0,10386899 0,10624186 ! sensory perception of chemical stimulus GO:0007606 108 87 0,000 0,10386899 0,10619609 ! gland development GO:0048732 170 87 0,000 0,10386899 0,10615035 ! vitamin metabolic process GO:0006766 117 87 0,000 0,10386899 0,10610466 ! forebrain development GO:0030900 151 87 0,000 0,10386899 0,106059 ! regulation of membrane potential GO:0042391 144 88 0,000 0,10500041 0,10716817 ! ossification GO:0001503 150 89 0,000 0,10613046 0,10827498 GO:0060348|bone development, ! nucleosome assembly GO:0006334 113 89 0,000 0,10613046 0,10822845 GO:0031497|chromatin assembly, ! regulation of DNA metabolic process GO:0051052 152 90 0,000 0,10725914 0,10933245 ! regulation of cyclic nucleotide metabolic process GO:0030799 161 90 0,000 0,10725914 0,10928551 ! skeletal muscle tissue development GO:0007519 135 90 0,000 0,10725914 0,10923861 GO:0060538|skeletal muscle organ development, ! transcription initiation GO:0006352 128 90 0,000 0,10725914 0,10919174 ! regulation of GTPase activity GO:0043087 149 90 0,000 0,10725914 0,10914492 ! nuclear import GO:0051170 153 90 0,000 0,10725914 0,10909814 ! regulation of protein localization GO:0032880 141 90 0,000 0,10725914 0,10905139 ! positive regulation of cell activation GO:0050867 146 90 0,000 0,10725914 0,10900469 GO:0002696|positive regulation of leukocyte activation, ! carboxylic acid catabolic process GO:0046395 132 91 0,000 0,10838646 0,11010319 GO:0016054|organic acid catabolic process, ! detection of stimulus GO:0051606 123 91 0,000 0,10838646 0,11005608 ! protein localization in nucleus GO:0034504 161 92 0,000 0,1095124 0,11115181 ! sterol metabolic process GO:0016125 136 92 0,000 0,1095124 0,11110429 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 141 93 0,000 0,11063698 0,11219725 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cell cycle arrest GO:0007050 171 93 0,000 0,11063698 0,11214932 ! protein-DNA complex assembly GO:0065004 119 93 0,000 0,11063698 0,11210143 ! rRNA processing GO:0006364 124 93 0,000 0,11063698 0,11205359 ! positive regulation of MAP kinase activity GO:0043406 143 93 0,000 0,11063698 0,11200578 ! regulation of nucleotide metabolic process GO:0006140 164 93 0,000 0,11063698 0,11195802 ! anterior/posterior pattern formation GO:0009952 141 93 0,000 0,11063698 0,1119103 ! negative regulation of multicellular organismal process GO:0051241 150 93 0,000 0,11063698 0,11186262 ! leukocyte differentiation GO:0002521 165 94 0,000 0,1117602 0,11295015 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 140 94 0,000 0,1117602 0,11290207 ! ribonucleoside triphosphate biosynthetic process GO:0009201 142 94 0,000 0,1117602 0,11285402 ! rRNA metabolic process GO:0016072 125 94 0,000 0,1117602 0,11280602 ! regulation of cell adhesion GO:0030155 187 94 0,000 0,1117602 0,11275806 ! hormone metabolic process GO:0042445 135 94 0,000 0,1117602 0,11271014 ! protein processing GO:0016485 127 94 0,000 0,1117602 0,11266226 ! nucleoside triphosphate biosynthetic process GO:0009142 143 95 0,000 0,11288205 0,11374485 ! anatomical structure homeostasis GO:0060249 152 95 0,000 0,11288205 0,11369657 ! ATP metabolic process GO:0046034 150 96 0,000 0,11400255 0,11477643 ! nucleosome organization GO:0034728 126 96 0,000 0,11400255 0,11472776 ! protein modification by small protein conjugation GO:0032446 153 96 0,000 0,11400255 0,11467912 ! female pregnancy GO:0007565 148 96 0,000 0,11400255 0,11463053 ! regulation of neurogenesis GO:0050767 179 97 0,000 0,11512168 0,1157068 ! reproductive developmental process GO:0003006 149 97 0,000 0,11512168 0,11565781 ! response to virus GO:0009615 141 98 0,000 0,11623946 0,11673138 ! polysaccharide metabolic process GO:0005976 141 98 0,000 0,11623946 0,116682 ! Wnt receptor signaling pathway GO:0016055 161 98 0,000 0,11623946 0,11663266 ! regulation of T cell activation GO:0050863 155 98 0,000 0,11623946 0,11658337 ! regulation of binding GO:0051098 164 99 0,000 0,11735589 0,11765337 ! electron transport chain GO:0022900 135 99 0,000 0,11735589 0,11760368 ! glycerophospholipid metabolic process GO:0006650 143 99 0,000 0,11735589 0,11755404 ! cell fate commitment GO:0045165 165 99 0,000 0,11735589 0,11750444 ! positive regulation of immune response GO:0050778 143 99 0,000 0,11735589 0,11745488 ! sulfur metabolic process GO:0006790 136 99 0,000 0,11735589 0,11740536 ! carbohydrate catabolic process GO:0016052 137 100 0,000 0,11847096 0,11847096