pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/11316-0-real-Sotiriou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of centrosome cycle GO:0046605 7 5 3,000 4,039E-11 9,289E-08 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 4,000 8,007E-10 9,208E-07 ! regulation of microtubule-based process GO:0032886 58 30 4,000 1,726E-09 1,323E-06 ! ribosome assembly GO:0042255 13 11 3,000 2,646E-09 1,521E-06 ! centrosome cycle GO:0007098 16 15 3,000 1,089E-08 5,01E-06 ! regulation of cytoskeleton organization GO:0051493 154 93 5,000 1,273E-08 4,881E-06 ! cell aging GO:0007569 32 21 3,000 4,74E-08 1,557E-05 ! microtubule organizing center organization GO:0031023 28 22 3,000 5,786E-08 1,663E-05 GO:0051297|centrosome organization, ! negative regulation of organelle organization GO:0010639 115 72 4,000 1,609E-07 4,111E-05 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 3,000 2,146E-07 4,936E-05 ! positive regulation of transcription factor activity GO:0051091 49 36 3,000 4,579E-07 9,575E-05 GO:0090047|positive regulation of transcription regulator activity, ! COPI coating of Golgi vesicle GO:0048205 14 10 2,000 6,008E-07 1,151E-04 GO:0048200|Golgi transport vesicle coating, ! positive regulation of DNA binding GO:0043388 57 41 3,000 7,824E-07 1,384E-04 ! Golgi vesicle budding GO:0048194 17 11 2,000 8,251E-07 1,355E-04 ! positive regulation of binding GO:0051099 59 43 3,000 9,511E-07 1,458E-04 ! ribonucleoprotein complex assembly GO:0022618 70 44 3,000 1,045E-06 1,502E-04 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 2,000 1,814E-06 2,454E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 1,907E-06 2,437E-04 ! aging GO:0007568 79 52 3,000 2,063E-06 2,498E-04 ! vesicle coating GO:0006901 25 15 2,000 2,264E-06 2,604E-04 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 2,000 3,376E-06 3,697E-04 ! membrane budding GO:0006900 29 17 2,000 3,376E-06 3,529E-04 ! regulation of transcription factor activity GO:0051090 97 63 3,000 4,479E-06 4,479E-04 GO:0090046|regulation of transcription regulator activity, ! G2/M transition of mitotic cell cycle GO:0000086 33 21 2,000 6,571E-06 6,297E-04 ! vesicle targeting GO:0006903 32 23 2,000 8,729E-06 8,031E-04 ! regulation of DNA binding GO:0051101 119 77 3,000 1E-05 8,846E-04 ! chromatin assembly GO:0031497 102 80 3,000 1,164E-05 9,919E-04 GO:0006334|nucleosome assembly, ! regulation of cell cycle process GO:0010564 122 81 3,000 1,223E-05 1,005E-03 ! microtubule cytoskeleton organization GO:0000226 120 84 3,000 1,414E-05 1,121E-03 ! protein-DNA complex assembly GO:0065004 107 84 3,000 1,414E-05 1,084E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 1,552E-05 1,151E-03 ! nucleosome organization GO:0034728 114 87 3,000 1,625E-05 1,168E-03 ! interphase GO:0051325 159 88 3,000 1,7E-05 1,185E-03 ! establishment of vesicle localization GO:0051650 45 30 2,000 1,984E-05 1,342E-03 ! regulation of binding GO:0051098 151 95 3,000 2,301E-05 1,512E-03 ! vesicle localization GO:0051648 47 32 2,000 2,418E-05 1,545E-03 ! negative regulation of protein ubiquitination GO:0031397 7 5 1,000 3,033E-05 1,885E-03 ! positive regulation of viral genome replication GO:0045070 8 5 1,000 3,033E-05 1,836E-03 ! regulation of retroviral genome replication GO:0045091 6 5 1,000 3,033E-05 1,789E-03 ! positive regulation of Rho GTPase activity GO:0032321 9 5 1,000 3,033E-05 1,744E-03 ! DNA topological change GO:0006265 8 6 1,000 4,545E-05 2,549E-03 ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 4,771E-05 2,613E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 5,938E-05 3,176E-03 ! vesicle organization GO:0016050 79 43 2,000 5,938E-05 3,104E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 6,355E-05 3,248E-03 ! regulation of focal adhesion formation GO:0051893 17 7 1,000 6,355E-05 3,178E-03 ! response to UV GO:0009411 75 46 2,000 7,278E-05 3,562E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 8,464E-05 4,056E-03 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 8,464E-05 3,973E-03 ! keratinocyte proliferation GO:0043616 12 8 1,000 8,464E-05 3,894E-03 ! positive regulation of Ras GTPase activity GO:0032320 20 8 1,000 8,464E-05 3,817E-03 ! establishment of organelle localization GO:0051656 85 52 2,000 1,052E-04 4,653E-03 ! positive regulation of GTPase activity GO:0043547 21 9 1,000 1,087E-04 4,718E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 1,000 1,087E-04 4,63E-03 ! regulation of stress fiber formation GO:0051492 20 9 1,000 1,087E-04 4,546E-03 ! DNA ligation GO:0006266 14 9 1,000 1,087E-04 4,465E-03 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,357E-04 5,477E-03 ! regulation of phosphatase activity GO:0010921 21 10 1,000 1,357E-04 5,383E-03 ! positive regulation of viral reproduction GO:0048524 15 10 1,000 1,357E-04 5,291E-03 ! regulation of actin filament bundle formation GO:0032231 21 10 1,000 1,357E-04 5,203E-03 ! negative regulation of protein kinase activity GO:0006469 99 57 2,000 1,384E-04 5,22E-03 ! negative regulation of kinase activity GO:0033673 100 58 2,000 1,458E-04 5,41E-03 ! regulation of Rho GTPase activity GO:0032319 18 11 1,000 1,657E-04 6,05E-03 ! negative regulation of transferase activity GO:0051348 105 61 2,000 1,695E-04 6,091E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 2,000 1,695E-04 5,997E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 2,000 1,779E-04 6,199E-03 ! organelle localization GO:0051640 96 62 2,000 1,779E-04 6,106E-03 ! positive regulation of cell growth GO:0030307 16 12 1,000 1,986E-04 6,719E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 2,000 2,047E-04 6,824E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 2,000 2,047E-04 6,726E-03 ! positive regulation of ligase activity GO:0051351 99 69 2,000 2,444E-04 7,916E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 2,000 2,659E-04 8,495E-03 ! negative regulation of microtubule depolymerization GO:0007026 31 14 1,000 2,733E-04 8,61E-03 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of caspase activity GO:0043154 20 14 1,000 2,733E-04 8,494E-03 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 2,733E-04 8,38E-03 ! regulation of ligase activity GO:0051340 114 75 2,000 3,127E-04 9,463E-03 ! regulation of protein ubiquitination GO:0031396 19 15 1,000 3,15E-04 9,408E-03 ! positive regulation of cell size GO:0045793 20 15 1,000 3,15E-04 9,288E-03 ! skin development GO:0043588 25 15 1,000 3,15E-04 9,17E-03 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 1,000 3,15E-04 9,055E-03 ! cellular response to unfolded protein GO:0034620 19 16 1,000 3,596E-04 0,01020999 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of dephosphorylation GO:0035303 33 16 1,000 3,596E-04 0,01008548 ! negative regulation of translation GO:0017148 22 16 1,000 3,596E-04 9,964E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 2,000 3,782E-04 0,01035485 GO:0010498|proteasomal protein catabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 1,000 4,071E-04 0,01101461 ! negative regulation of peptidase activity GO:0010466 23 17 1,000 4,071E-04 0,01088653 ! regulation of viral genome replication GO:0045069 24 17 1,000 4,071E-04 0,0107614 ! Golgi vesicle transport GO:0048193 138 85 2,000 4,519E-04 0,01181142 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 4,574E-04 0,01182145 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 5,107E-04 0,01305097 ! apoptotic nuclear changes GO:0030262 24 19 1,000 5,107E-04 0,01290756 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 5,107E-04 0,01276726 ! chromosome condensation GO:0030261 31 20 1,000 5,668E-04 0,01401781 ! positive regulation of B cell activation GO:0050871 31 20 1,000 5,668E-04 0,01386868 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 6,258E-04 0,01515045 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 1,000 6,258E-04 0,01499263 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 6,258E-04 0,01483807 ! response to light stimulus GO:0009416 153 96 2,000 6,452E-04 0,01514189 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 6,876E-04 0,01597448 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 6,876E-04 0,01581474 GO:0010810|regulation of cell-substrate adhesion, ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 7,057E-04 0,01607067 ! regulation of translation GO:0006417 151 100 2,000 7,267E-04 0,01638564 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 7,523E-04 0,01679785 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 7,523E-04 0,01663633 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 7,523E-04 0,01647789 ! regulation of viral reproduction GO:0050792 32 23 1,000 7,523E-04 0,01632244 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 7,523E-04 0,01616989 ! fat cell differentiation GO:0045444 37 24 1,000 8,197E-04 0,01745726 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 8,9E-04 0,01878044 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of protein modification process GO:0031400 50 26 1,000 9,631E-04 0,02013827 ! regulation of B cell activation GO:0050864 42 28 1,000 1,118E-03 0,02316015 ! RNA export from nucleus GO:0006405 44 33 1,000 1,553E-03 0,03188541 ! nucleus organization GO:0006997 49 33 1,000 1,553E-03 0,03160324 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 1,553E-03 0,03132601 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 1,648E-03 0,03295808 ! keratinocyte differentiation GO:0030216 47 35 1,000 1,746E-03 0,03461599 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 1,746E-03 0,03432013 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 2,165E-03 0,04219276 ! response to calcium ion GO:0051592 58 40 1,000 2,276E-03 0,04399167 ! epidermal cell differentiation GO:0009913 53 40 1,000 2,276E-03 0,04362508 ! response to insulin stimulus GO:0032868 63 43 1,000 2,626E-03 0,04992164 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 2,748E-03 0,05181304 ! positive regulation of cell cycle GO:0045787 77 45 1,000 2,873E-03 0,05372287 ! regulation of translational initiation GO:0006446 64 45 1,000 2,873E-03 0,05328962 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 3E-03 0,05520531 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 3,13E-03 0,05713827 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! nuclear export GO:0051168 69 48 1,000 3,263E-03 0,05908793 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 3,535E-03 0,06352763 ! positive regulation of growth GO:0045927 67 50 1,000 3,535E-03 0,06303517 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 4,415E-03 0,07811679 ! chromosome segregation GO:0007059 83 57 1,000 4,571E-03 0,08025101 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 4,571E-03 0,07964305 ! negative regulation of cell growth GO:0030308 106 62 1,000 5,386E-03 0,09314061 ! negative regulation of cell size GO:0045792 108 64 1,000 5,729E-03 0,09833981 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 5,729E-03 0,09761137 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 5,729E-03 0,09689364 ! regulation of caspase activity GO:0043281 97 65 1,000 5,905E-03 0,09913082 ! regulation of actin filament-based process GO:0032970 99 66 1,000 6,083E-03 0,10137631 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 6,083E-03 0,10064698 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 6,263E-03 0,10288957 ! regulation of Ras GTPase activity GO:0032318 110 68 1,000 6,446E-03 0,10513993 ! response to metal ion GO:0010038 103 70 1,000 6,818E-03 0,11043504 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 6,818E-03 0,10966277 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 7,008E-03 0,11193466 ! regulation of peptidase activity GO:0052547 106 72 1,000 7,2E-03 0,11421316 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 7,2E-03 0,11343088 GO:0045937|positive regulation of phosphate metabolic process, ! mitochondrion organization GO:0007005 104 73 1,000 7,395E-03 0,1157055 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 7,592E-03 0,1179863 ! response to inorganic substance GO:0010035 115 75 1,000 7,792E-03 0,12027301 ! negative regulation of growth GO:0045926 123 75 1,000 7,792E-03 0,11947119 ! response to unfolded protein GO:0006986 99 76 1,000 7,993E-03 0,12175371 ! positive regulation of protein modification process GO:0031401 107 78 1,000 8,404E-03 0,12716623 ! regulation of GTPase activity GO:0043087 129 80 1,000 8,824E-03 0,1326483 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 8,836E-03 0,13196446 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 8,836E-03 0,13111308 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 8,836E-03 0,13027261 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 8,836E-03 0,12944285 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 8,836E-03 0,12862359 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 8,836E-03 0,12781463 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 8,836E-03 0,12701579 ! sleep GO:0030431 11 5 0,000 8,836E-03 0,12622687 ! negative regulation of bone resorption GO:0045779 10 5 0,000 8,836E-03 0,1254477 ! nucleotide-sugar transport GO:0015780 8 5 0,000 8,836E-03 0,12467808 ! regulation of interferon-beta production GO:0032648 5 5 0,000 8,836E-03 0,12391785 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 8,836E-03 0,12316683 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 8,836E-03 0,12242486 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 8,836E-03 0,12169178 ! tongue development GO:0043586 6 5 0,000 8,836E-03 0,12096742 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 8,836E-03 0,12025164 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 8,836E-03 0,11954428 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 8,836E-03 0,11884519 ! cobalt ion transport GO:0006824 9 5 0,000 8,836E-03 0,11815423 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 8,836E-03 0,11747125 ! SMAD protein complex assembly GO:0007183 9 5 0,000 8,836E-03 0,11679613 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 8,836E-03 0,11612872 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 8,836E-03 0,1154689 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 8,836E-03 0,11481654 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 8,836E-03 0,1141715 ! embryonic camera-type eye development GO:0031076 8 5 0,000 8,836E-03 0,11353367 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 8,836E-03 0,11290293 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 8,836E-03 0,11227915 ! adaptation of signaling pathway GO:0022401 7 5 0,000 8,836E-03 0,11166224 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 8,836E-03 0,11105206 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 8,836E-03 0,11044852 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 8,836E-03 0,1098515 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 8,836E-03 0,1092609 ! positive regulation of histone modification GO:0031058 5 5 0,000 8,836E-03 0,10867661 ! malate metabolic process GO:0006108 7 5 0,000 8,836E-03 0,10809855 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 8,836E-03 0,1075266 ! behavioral response to pain GO:0048266 7 5 0,000 8,836E-03 0,10696067 ! clathrin coat assembly GO:0048268 11 5 0,000 8,836E-03 0,10640066 ! phototransduction, visible light GO:0007603 6 5 0,000 8,836E-03 0,10584649 ! regulation of dopamine uptake GO:0051584 9 5 0,000 8,836E-03 0,10529807 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 8,836E-03 0,10475529 ! mating behavior GO:0007617 6 5 0,000 8,836E-03 0,10421809 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 8,836E-03 0,10368636 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 8,836E-03 0,10316003 ! rhythmic behavior GO:0007622 12 5 0,000 8,836E-03 0,10263902 ! copulation GO:0007620 7 5 0,000 8,836E-03 0,10212325 ! glial cell fate commitment GO:0021781 12 5 0,000 8,836E-03 0,10161263 ! protein maturation by protein folding GO:0022417 12 5 0,000 8,836E-03 0,1011071 ! embryonic hemopoiesis GO:0035162 10 5 0,000 8,836E-03 0,10060657 ! regulation of potassium ion transport GO:0043266 9 5 0,000 8,836E-03 0,10011097 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 8,836E-03 0,09962023 ! apoptotic cell clearance GO:0043277 13 5 0,000 8,836E-03 0,09913428 ! lipoprotein particle clearance GO:0034381 9 5 0,000 8,836E-03 0,09865304 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 8,836E-03 0,09817646 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 8,836E-03 0,09770446 ! response to protozoan GO:0001562 9 5 0,000 8,836E-03 0,09723697 ! positive regulation of glycolysis GO:0045821 11 5 0,000 8,836E-03 0,09677394 ! lymph vessel development GO:0001945 7 5 0,000 8,836E-03 0,09631529 ! endochondral ossification GO:0001958 12 5 0,000 8,836E-03 0,09586098 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 8,836E-03 0,09541092 ! parathyroid gland development GO:0060017 8 5 0,000 8,836E-03 0,09496508 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 8,836E-03 0,09452338 ! anagen GO:0042640 6 5 0,000 8,836E-03 0,09408577 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 8,836E-03 0,0936522 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 8,836E-03 0,0932226 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 8,836E-03 0,09279693 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 8,836E-03 0,09237512 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 8,836E-03 0,09195714 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 8,836E-03 0,09154291 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 8,836E-03 0,09113241 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 8,836E-03 0,09072557 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 8,836E-03 0,09032234 ! cardiac muscle fiber development GO:0048739 7 5 0,000 8,836E-03 0,08992269 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 8,836E-03 0,08952655 ! neutrophil mediated immunity GO:0002446 6 5 0,000 8,836E-03 0,08913389 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 8,836E-03 0,08874466 ! ovulation GO:0030728 6 5 0,000 8,836E-03 0,08835881 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 8,836E-03 0,08797631 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 8,836E-03 0,0875971 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 8,836E-03 0,08722115 ! response to pH GO:0009268 9 5 0,000 8,836E-03 0,08684841 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 8,836E-03 0,08647884 ! proline biosynthetic process GO:0006561 6 5 0,000 8,836E-03 0,0861124 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 8,836E-03 0,08574906 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 8,836E-03 0,08538877 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 8,836E-03 0,08503149 ! polyol catabolic process GO:0046174 7 5 0,000 8,836E-03 0,0846772 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 8,836E-03 0,08432584 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 8,836E-03 0,08397738 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 8,836E-03 0,0836318 ! sister chromatid cohesion GO:0007062 9 5 0,000 8,836E-03 0,08328904 ! nerve growth factor processing GO:0032455 7 5 0,000 8,836E-03 0,08294909 ! urea metabolic process GO:0019627 6 5 0,000 8,836E-03 0,0826119 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 8,836E-03 0,08227744 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 8,836E-03 0,08194567 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 8,836E-03 0,08161657 ! neutrophil activation GO:0042119 5 5 0,000 8,836E-03 0,08129011 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 8,836E-03 0,08096624 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 8,836E-03 0,08064495 ! response to food GO:0032094 5 5 0,000 8,836E-03 0,08032619 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 8,836E-03 0,08000995 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 8,836E-03 0,07969618 ! paraxial mesoderm development GO:0048339 9 5 0,000 8,836E-03 0,07938487 ! forebrain neuron development GO:0021884 7 5 0,000 8,836E-03 0,07907598 ! melanosome organization GO:0032438 7 5 0,000 8,836E-03 0,07876948 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 8,836E-03 0,07846535 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 8,836E-03 0,07816356 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 8,836E-03 0,07786409 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 8,836E-03 0,0775669 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 8,836E-03 0,07727197 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 8,836E-03 0,07697927 ! nucleoside transport GO:0015858 6 5 0,000 8,836E-03 0,07668878 ! nucleoside salvage GO:0043174 7 5 0,000 8,836E-03 0,07640048 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 8,836E-03 0,07611433 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 8,836E-03 0,07583032 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 8,836E-03 0,07554843 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 8,836E-03 0,07526862 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 8,836E-03 0,07499087 ! early endosome to late endosome transport GO:0045022 11 5 0,000 8,836E-03 0,07471517 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 8,836E-03 0,07444149 ! depyrimidination GO:0045008 8 5 0,000 8,836E-03 0,07416981 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 8,836E-03 0,0739001 ! 5S class rRNA transcription GO:0042791 8 5 0,000 8,836E-03 0,07363234 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 8,836E-03 0,07336652 ! neuronal ion channel clustering GO:0045161 7 5 0,000 8,836E-03 0,07310261 ! sodium ion homeostasis GO:0055078 6 5 0,000 8,836E-03 0,0728406 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 8,836E-03 0,07258045 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 8,836E-03 0,07232216 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 8,836E-03 0,0720657 ! monocyte differentiation GO:0030224 8 5 0,000 8,836E-03 0,07181105 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 8,836E-03 0,07155819 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 8,836E-03 0,07130711 ! centrosome duplication GO:0051298 5 5 0,000 8,836E-03 0,07105779 ! response to UV-C GO:0010225 6 5 0,000 8,836E-03 0,0708102 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 8,836E-03 0,07056433 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 8,836E-03 0,07032016 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 8,836E-03 0,07007768 ! regulation of dendrite development GO:0050773 12 5 0,000 8,836E-03 0,06983686 ! peptidyl-arginine modification GO:0018195 7 5 0,000 8,836E-03 0,06959769 ! positive regulation of organ growth GO:0046622 6 5 0,000 8,836E-03 0,06936016 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 8,836E-03 0,06912424 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 8,836E-03 0,06888992 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 8,836E-03 0,06865719 ! regulation of dopamine secretion GO:0014059 12 5 0,000 8,836E-03 0,06842602 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 8,836E-03 0,0681964 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 8,836E-03 0,06796832 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 8,836E-03 0,06774176 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 8,836E-03 0,0675167 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 8,836E-03 0,06729314 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 8,836E-03 0,06707105 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 8,836E-03 0,06685042 ! neural tube patterning GO:0021532 6 5 0,000 8,836E-03 0,06663124 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 8,836E-03 0,06641349 ! histone demethylation GO:0016577 9 5 0,000 8,836E-03 0,06619716 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 8,836E-03 0,06598223 ! regulation of sterol transport GO:0032371 7 5 0,000 8,836E-03 0,0657687 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 8,836E-03 0,06555654 ! enteric nervous system development GO:0048484 8 5 0,000 8,836E-03 0,06534575 ! establishment of planar polarity GO:0001736 6 5 0,000 8,836E-03 0,0651363 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 8,836E-03 0,0649282 ! muscle cell proliferation GO:0033002 8 5 0,000 8,836E-03 0,06472142 ! transcription termination GO:0006353 8 5 0,000 8,836E-03 0,06451596 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 8,836E-03 0,06431179 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 8,836E-03 0,06410892 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 8,836E-03 0,06390732 ! regulation of respiratory burst GO:0060263 8 5 0,000 8,836E-03 0,06370698 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 8,836E-03 0,0635079 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 8,836E-03 0,06331005 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 8,836E-03 0,06311344 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 8,836E-03 0,06291804 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 8,836E-03 0,06272385 ! apical protein localization GO:0045176 6 5 0,000 8,836E-03 0,06253085 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 8,836E-03 0,06233904 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 8,836E-03 0,0621484 ! galactolipid metabolic process GO:0019374 7 5 0,000 8,836E-03 0,06195892 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 8,836E-03 0,0617706 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 8,836E-03 0,06158341 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 8,836E-03 0,06139736 ! triglyceride catabolic process GO:0019433 6 5 0,000 8,836E-03 0,06121243 ! glial cell migration GO:0008347 10 5 0,000 8,836E-03 0,06102861 ! determination of adult lifespan GO:0008340 8 5 0,000 8,836E-03 0,06084589 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 8,836E-03 0,06066426 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 8,836E-03 0,06048371 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 8,836E-03 0,06030423 ! somatic stem cell maintenance GO:0035019 13 5 0,000 8,836E-03 0,06012582 ! cerebellar cortex formation GO:0021697 6 5 0,000 8,836E-03 0,05994846 ! neural plate development GO:0001840 6 5 0,000 8,836E-03 0,05977214 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 8,836E-03 0,05959685 ! regulation of sensory perception GO:0051931 6 5 0,000 8,836E-03 0,05942259 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 8,836E-03 0,05924935 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 8,836E-03 0,05907711 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 8,836E-03 0,05890587 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 8,836E-03 0,05873563 ! sensory cilium assembly GO:0035058 6 5 0,000 8,836E-03 0,05856636 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 8,836E-03 0,05839807 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 8,836E-03 0,05823074 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 8,836E-03 0,05806436 ! spindle assembly GO:0051225 5 5 0,000 8,836E-03 0,05789894 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 8,836E-03 0,05773445 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 8,836E-03 0,0575709 ! protein amino acid prenylation GO:0018346 9 5 0,000 8,836E-03 0,05740827 ! organ regeneration GO:0031100 7 5 0,000 8,836E-03 0,05724655 ! NAD biosynthetic process GO:0009435 7 5 0,000 8,836E-03 0,05708575 ! carnitine metabolic process GO:0009437 5 5 0,000 8,836E-03 0,05692585 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 8,836E-03 0,05676683 ! cellular anion homeostasis GO:0030002 6 5 0,000 8,836E-03 0,05660871 GO:0055081|anion homeostasis, ! response to protein stimulus GO:0051789 111 81 1,000 9,037E-03 0,05773931 ! positive regulation of cell activation GO:0050867 120 81 1,000 9,037E-03 0,05757937 GO:0002696|positive regulation of leukocyte activation, ! regulation of cell adhesion GO:0030155 159 83 1,000 9,471E-03 0,06017675 ! cell cycle arrest GO:0007050 150 86 1,000 0,01013922 0,064243 ! tRNA transcription GO:0009304 11 6 0,000 0,01059397 0,06693991 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01059397 0,06675651 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01059397 0,06657412 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01059397 0,06639272 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01059397 0,0662123 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01059397 0,06603286 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01059397 0,0658544 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01059397 0,06567689 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01059397 0,06550034 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01059397 0,06532474 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01059397 0,06515007 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01059397 0,06497634 ! prostate gland development GO:0030850 9 6 0,000 0,01059397 0,06480353 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01059397 0,06463164 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01059397 0,06446065 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01059397 0,06429057 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01059397 0,06412139 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01059397 0,06395309 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01059397 0,06378567 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01059397 0,06361913 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01059397 0,06345346 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01059397 0,06328864 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01059397 0,06312468 ! neuron adhesion GO:0007158 9 6 0,000 0,01059397 0,06296157 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01059397 0,0627993 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01059397 0,06263786 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01059397 0,06247725 ! signal peptide processing GO:0006465 8 6 0,000 0,01059397 0,06231746 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01059397 0,06215849 ! mRNA stabilization GO:0048255 15 6 0,000 0,01059397 0,06200032 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01059397 0,06184296 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01059397 0,0616864 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01059397 0,06153062 ! opsonization GO:0008228 8 6 0,000 0,01059397 0,06137563 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01059397 0,06122142 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01059397 0,06106799 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01059397 0,06091532 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01059397 0,06076341 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01059397 0,06061226 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01059397 0,06046185 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01059397 0,0603122 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01059397 0,06016328 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01059397 0,06001509 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01059397 0,05986763 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01059397 0,0597209 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01059397 0,05957488 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01059397 0,05942958 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01059397 0,05928498 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01059397 0,05914109 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01059397 0,05899789 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01059397 0,05885538 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01059397 0,05871356 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01059397 0,05857242 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01059397 0,05843196 ! thymic T cell selection GO:0045061 12 6 0,000 0,01059397 0,05829217 ! protein lipoylation GO:0009249 10 6 0,000 0,01059397 0,05815305 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01059397 0,05801459 ! pigment granule organization GO:0048753 11 6 0,000 0,01059397 0,05787679 ! drug transport GO:0015893 6 6 0,000 0,01059397 0,05773964 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01059397 0,05760314 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01059397 0,05746728 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01059397 0,05733206 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01059397 0,05719748 ! histidine metabolic process GO:0006547 6 6 0,000 0,01059397 0,05706353 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01059397 0,0569302 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01059397 0,0567975 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01059397 0,05666541 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01059397 0,05653394 ! adenohypophysis development GO:0021984 10 6 0,000 0,01059397 0,05640307 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01059397 0,05627281 ! hyperosmotic response GO:0006972 8 6 0,000 0,01059397 0,05614315 ! microtubule nucleation GO:0007020 10 6 0,000 0,01059397 0,05601409 ! ER overload response GO:0006983 7 6 0,000 0,01059397 0,05588561 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01059397 0,05575773 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01059397 0,05563043 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01059397 0,05550371 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01059397 0,05537756 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01059397 0,05525199 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01059397 0,05512698 ! response to dietary excess GO:0002021 7 6 0,000 0,01059397 0,05500254 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01059397 0,05487866 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01059397 0,05475534 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01059397 0,05463257 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01059397 0,05451035 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01059397 0,05438868 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01059397 0,05426754 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01059397 0,05414695 ! neuron apoptosis GO:0051402 8 6 0,000 0,01059397 0,05402689 ! organic alcohol transport GO:0015850 9 6 0,000 0,01059397 0,05390736 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01059397 0,05378836 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01059397 0,05366988 ! male sex determination GO:0030238 9 6 0,000 0,01059397 0,05355193 ! carnitine transport GO:0015879 8 6 0,000 0,01059397 0,05343449 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01059397 0,05331756 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01059397 0,05320115 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01059397 0,05308524 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01059397 0,05296984 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01059397 0,05285494 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01059397 0,05274053 ! parturition GO:0007567 12 6 0,000 0,01059397 0,05262662 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01059397 0,0525132 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01059397 0,05240027 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01059397 0,05228783 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01059397 0,05217586 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01059397 0,05206437 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01059397 0,05195336 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01059397 0,05184282 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01059397 0,05173275 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01059397 0,05162315 ! macrophage differentiation GO:0030225 10 6 0,000 0,01059397 0,05151401 ! astrocyte development GO:0014002 14 6 0,000 0,01059397 0,05140533 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01059397 0,05129711 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01059397 0,05118934 ! interaction with symbiont GO:0051702 8 6 0,000 0,01059397 0,05108203 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01059397 0,05097516 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01059397 0,05086874 ! eating behavior GO:0042755 6 6 0,000 0,01059397 0,05076276 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01059397 0,05065723 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01059397 0,05055213 ! response to copper ion GO:0046688 9 6 0,000 0,01059397 0,05044747 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01059397 0,05034324 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01059397 0,05023944 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01059397 0,05013606 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01059397 0,05003312 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01059397 0,04993059 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01059397 0,04982848 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01059397 0,04972679 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01059397 0,04962551 ! gas homeostasis GO:0033483 11 6 0,000 0,01059397 0,04952465 ! hair follicle maturation GO:0048820 7 6 0,000 0,01059397 0,04942419 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01059397 0,04932414 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01059397 0,0492245 ! Schwann cell development GO:0014044 14 6 0,000 0,01059397 0,04912526 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01059397 0,04902641 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01059397 0,04892797 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01059397 0,04882991 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01059397 0,04873225 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01059397 0,04863498 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01059397 0,0485381 ! histone ubiquitination GO:0016574 7 6 0,000 0,01059397 0,0484416 ! regulation of meiosis GO:0040020 10 6 0,000 0,01059397 0,04834549 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01059397 0,04824976 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01059397 0,0481544 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01059397 0,04805942 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01059397 0,04796482 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01059397 0,04787058 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01059397 0,04777672 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01059397 0,04768322 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01059397 0,04759009 ! receptor internalization GO:0031623 9 6 0,000 0,01059397 0,04749732 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01059397 0,04740492 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01059397 0,04731287 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01059397 0,04722118 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01059397 0,04712984 ! protein deubiquitination GO:0016579 8 6 0,000 0,01059397 0,04703886 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01059397 0,04694822 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01059397 0,04685794 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01059397 0,046768 ! axonal fasciculation GO:0007413 9 6 0,000 0,01059397 0,0466784 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01059397 0,04658915 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01059397 0,04650024 ! midbrain development GO:0030901 6 6 0,000 0,01059397 0,04641167 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01059397 0,04632344 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01059397 0,04623554 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01059397 0,04614797 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01059397 0,04606073 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01059397 0,04597382 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01059397 0,04588724 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01059397 0,04580099 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01059397 0,04571506 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01059397 0,04562945 ! adult feeding behavior GO:0008343 6 6 0,000 0,01059397 0,04554416 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01059397 0,04545919 ! blastocyst growth GO:0001832 15 6 0,000 0,01059397 0,04537454 ! pigment granule transport GO:0051904 12 6 0,000 0,01059397 0,0452902 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01059397 0,04520617 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01059397 0,04512246 ! catecholamine transport GO:0051937 7 6 0,000 0,01059397 0,04503905 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01059397 0,04495595 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01059397 0,04487316 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01059397 0,04479067 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01059397 0,04470849 ! protein prenylation GO:0018342 10 6 0,000 0,01059397 0,04462661 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01059397 0,04454502 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01059397 0,04446374 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01059397 0,04438275 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01059397 0,04430205 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01059397 0,04422165 ! establishment of RNA localization GO:0051236 128 88 1,000 0,01059585 0,04414939 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! RNA localization GO:0006403 135 91 1,000 0,01129766 0,04698844 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01234904 0,05126857 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01234904 0,05117619 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01234904 0,05108415 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01234904 0,05099243 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01234904 0,05090105 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01234904 0,05080999 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01234904 0,05071926 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01234904 0,05062885 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01234904 0,05053877 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01234904 0,050449 ! reproductive behavior GO:0019098 12 7 0,000 0,01234904 0,05035955 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01234904 0,05027042 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01234904 0,0501816 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01234904 0,0500931 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01234904 0,0500049 ! oligopeptide transport GO:0006857 11 7 0,000 0,01234904 0,04991702 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01234904 0,04982945 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01234904 0,04974218 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,01234904 0,04965522 ! RNA methylation GO:0001510 11 7 0,000 0,01234904 0,04956856 ! pericardium development GO:0060039 8 7 0,000 0,01234904 0,04948221 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01234904 0,04939615 ! fibril organization GO:0043206 13 7 0,000 0,01234904 0,04931039 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01234904 0,04922493 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01234904 0,04913977 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01234904 0,0490549 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01234904 0,04897032 ! lipoprotein transport GO:0042953 9 7 0,000 0,01234904 0,04888603 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01234904 0,04880204 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01234904 0,04871833 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01234904 0,04863491 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01234904 0,04855177 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01234904 0,04846892 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01234904 0,04838635 ! chemosensory behavior GO:0007635 9 7 0,000 0,01234904 0,04830406 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01234904 0,04822205 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01234904 0,04814032 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01234904 0,04805886 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01234904 0,04797768 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01234904 0,04789677 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01234904 0,04781614 ! reflex GO:0060004 12 7 0,000 0,01234904 0,04773577 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01234904 0,04765568 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01234904 0,04757586 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01234904 0,0474963 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01234904 0,047417 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01234904 0,04733798 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01234904 0,04725921 ! spinal cord patterning GO:0021511 7 7 0,000 0,01234904 0,04718071 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01234904 0,04710246 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01234904 0,04702448 ! adrenal gland development GO:0030325 17 7 0,000 0,01234904 0,04694675 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01234904 0,04686928 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01234904 0,04679207 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01234904 0,04671511 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01234904 0,0466384 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01234904 0,04656194 ! endosome organization GO:0007032 10 7 0,000 0,01234904 0,04648574 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01234904 0,04640978 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01234904 0,04633407 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01234904 0,04625861 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01234904 0,04618339 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01234904 0,04610842 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01234904 0,04603369 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01234904 0,0459592 ! galactose metabolic process GO:0006012 10 7 0,000 0,01234904 0,04588495 ! vesicle fusion GO:0006906 15 7 0,000 0,01234904 0,04581095 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01234904 0,04573718 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01234904 0,04566364 ! organ growth GO:0035265 11 7 0,000 0,01234904 0,04559035 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01234904 0,04551729 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01234904 0,04544446 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01234904 0,04537186 ! retinol metabolic process GO:0042572 9 7 0,000 0,01234904 0,0452995 ! behavioral fear response GO:0001662 13 7 0,000 0,01234904 0,04522737 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01234904 0,04515546 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01234904 0,04508379 ! rRNA modification GO:0000154 12 7 0,000 0,01234904 0,04501234 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01234904 0,04494112 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01234904 0,04487012 ! response to UV-B GO:0010224 11 7 0,000 0,01234904 0,04479935 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01234904 0,0447288 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01234904 0,04465847 ! intermediate filament organization GO:0045109 11 7 0,000 0,01234904 0,04458836 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01234904 0,04451847 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01234904 0,0444488 ! fibrinolysis GO:0042730 9 7 0,000 0,01234904 0,04437935 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01234904 0,04431012 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01234904 0,0442411 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01234904 0,0441723 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01234904 0,0441037 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01234904 0,04403533 ! response to tropane GO:0014073 13 7 0,000 0,01234904 0,04396716 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01234904 0,04389921 ! melanosome localization GO:0032400 10 7 0,000 0,01234904 0,04383146 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01234904 0,04376392 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01234904 0,04369659 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01234904 0,04362947 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01234904 0,04356256 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01234904 0,04349584 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01234904 0,04342934 ! mast cell activation GO:0045576 9 7 0,000 0,01234904 0,04336303 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01234904 0,04329693 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01234904 0,04323103 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01234904 0,04316533 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01234904 0,04309983 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01234904 0,04303452 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01234904 0,04296942 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01234904 0,04290451 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01234904 0,0428398 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01234904 0,04277528 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01234904 0,04271096 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01234904 0,04264683 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01234904 0,04258289 ! response to tumor cell GO:0002347 12 7 0,000 0,01234904 0,04251914 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01234904 0,04245558 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01234904 0,04239222 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01234904 0,04232904 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,01234904 0,04226605 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01234904 0,04220325 ! diuresis GO:0030146 12 7 0,000 0,01234904 0,04214063 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01234904 0,0420782 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01234904 0,04201596 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01234904 0,04195389 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01234904 0,04189201 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01234904 0,04183032 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01234904 0,0417688 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01234904 0,04170747 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01234904 0,04164631 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01234904 0,04158534 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01234904 0,04152454 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01234904 0,04146392 ! lymph node development GO:0048535 9 7 0,000 0,01234904 0,04140348 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01234904 0,04134321 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01234904 0,04128312 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01234904 0,0412232 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01234904 0,04116346 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01234904 0,04110389 ! ATP catabolic process GO:0006200 10 7 0,000 0,01234904 0,04104449 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01234904 0,04098526 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01234904 0,0409262 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01234904 0,04086732 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01234904 0,0408086 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01234904 0,04075005 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01234904 0,04069167 ! muscle adaptation GO:0043500 12 7 0,000 0,01234904 0,04063346 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01234904 0,04057541 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01234904 0,04051753 ! retina homeostasis GO:0001895 9 7 0,000 0,01234904 0,04045981 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01234904 0,04040226 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01234904 0,04034487 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01234904 0,04028764 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01234904 0,04023057 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01234904 0,04017367 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01234904 0,04011693 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01234904 0,04006035 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 0,01251174 0,04053099 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,01251174 0,04047398 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01410109 0,04555128 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01410109 0,0454874 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,01410109 0,04542369 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01410109 0,04536016 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01410109 0,04529681 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01410109 0,04523363 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01410109 0,04517063 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01410109 0,04510781 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01410109 0,04504516 ! phosphate transport GO:0006817 10 8 0,000 0,01410109 0,04498268 ! N-glycan processing GO:0006491 12 8 0,000 0,01410109 0,04492038 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01410109 0,04485825 ! UTP metabolic process GO:0046051 8 8 0,000 0,01410109 0,04479629 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01410109 0,0447345 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01410109 0,04467289 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01410109 0,04461144 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01410109 0,04455016 ! succinate metabolic process GO:0006105 14 8 0,000 0,01410109 0,04448905 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01410109 0,0444281 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01410109 0,04436733 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01410109 0,04430671 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01410109 0,04424627 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01410109 0,04418599 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01410109 0,04412587 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01410109 0,04406592 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01410109 0,04400613 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01410109 0,0439465 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01410109 0,04388703 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01410109 0,04382772 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01410109 0,04376858 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01410109 0,04370959 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01410109 0,04365076 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01410109 0,04359209 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01410109 0,04353358 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01410109 0,04347522 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01410109 0,04341702 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01410109 0,04335898 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01410109 0,04330109 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01410109 0,04324335 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01410109 0,04318577 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01410109 0,04312834 ! melanin metabolic process GO:0006582 12 8 0,000 0,01410109 0,04307107 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01410109 0,04301395 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01410109 0,04295697 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01410109 0,04290015 ! macrophage activation GO:0042116 12 8 0,000 0,01410109 0,04284348 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01410109 0,04278696 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01410109 0,04273059 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01410109 0,04267436 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01410109 0,04261829 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01410109 0,04256236 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01410109 0,04250657 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01410109 0,04245094 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01410109 0,04239544 ! ruffle organization GO:0031529 11 8 0,000 0,01410109 0,0423401 ! osteoblast development GO:0002076 13 8 0,000 0,01410109 0,0422849 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01410109 0,04222984 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01410109 0,04217492 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01410109 0,04212015 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01410109 0,04206552 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01410109 0,04201103 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01410109 0,04195668 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01410109 0,04190247 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01410109 0,04184841 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01410109 0,04179448 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01410109 0,04174069 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01410109 0,04168704 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01410109 0,04163352 ! segment specification GO:0007379 10 8 0,000 0,01410109 0,04158015 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01410109 0,04152691 ! cellular extravasation GO:0045123 11 8 0,000 0,01410109 0,0414738 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01410109 0,04142084 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01410109 0,041368 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01410109 0,04131531 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01410109 0,04126274 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01410109 0,04121031 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01410109 0,04115801 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01410109 0,04110585 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01410109 0,04105382 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01410109 0,04100192 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01410109 0,04095015 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01410109 0,04089851 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01410109 0,040847 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01410109 0,04079562 ! icosanoid secretion GO:0032309 12 8 0,000 0,01410109 0,04074437 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01410109 0,04069324 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01410109 0,04064225 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01410109 0,04059138 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01410109 0,04054064 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01410109 0,04049003 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01410109 0,04043954 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01410109 0,04038918 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01410109 0,04033895 ! sterol catabolic process GO:0016127 9 8 0,000 0,01410109 0,04028884 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01410109 0,04023885 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01410109 0,04018899 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01410109 0,04013925 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01410109 0,04008964 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01410109 0,04004014 ! prophase GO:0051324 11 8 0,000 0,01410109 0,03999077 ! S phase GO:0051320 8 8 0,000 0,01410109 0,03994152 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01410109 0,03989239 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01410109 0,03984338 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01410109 0,0397945 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01410109 0,03974573 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01410109 0,03969708 ! hormone catabolic process GO:0042447 13 8 0,000 0,01410109 0,03964855 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01410109 0,03960014 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01410109 0,03955185 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01410109 0,03950367 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01410109 0,03945561 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01410109 0,03940767 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01410109 0,03935985 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01410109 0,03931214 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01410109 0,03926455 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01410109 0,03921707 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01410109 0,0391697 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01410109 0,03912245 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01410109 0,03907532 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01410109 0,0390283 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01410109 0,03898139 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01410109 0,03893459 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01410109 0,03888791 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01585014 0,04365907 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01585014 0,04360685 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01585014 0,04355475 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01585014 0,04350278 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01585014 0,04345092 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01585014 0,0433992 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01585014 0,04334759 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01585014 0,04329611 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01585014 0,04324475 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01585014 0,04319351 ! GTP metabolic process GO:0046039 9 9 0,000 0,01585014 0,0431424 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01585014 0,0430914 ! social behavior GO:0035176 14 9 0,000 0,01585014 0,04304053 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01585014 0,04298977 ! artery development GO:0060840 19 9 0,000 0,01585014 0,04293913 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01585014 0,04288862 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01585014 0,04283822 ! response to pain GO:0048265 16 9 0,000 0,01585014 0,04278794 ! protein complex disassembly GO:0043241 17 9 0,000 0,01585014 0,04273778 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01585014 0,04268773 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01585014 0,04263781 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01585014 0,042588 ! lung alveolus development GO:0048286 17 9 0,000 0,01585014 0,0425383 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01585014 0,04248872 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01585014 0,04243926 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01585014 0,04238991 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01585014 0,04234068 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01585014 0,04229156 ! protein targeting to ER GO:0045047 19 9 0,000 0,01585014 0,04224256 ! T cell selection GO:0045058 18 9 0,000 0,01585014 0,04219366 ! endoderm development GO:0007492 12 9 0,000 0,01585014 0,04214488 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01585014 0,04209622 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01585014 0,04204766 ! arginine catabolic process GO:0006527 10 9 0,000 0,01585014 0,04199922 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01585014 0,04195089 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01585014 0,04190267 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01585014 0,04185456 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01585014 0,04180657 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01585014 0,04175868 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01585014 0,0417109 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01585014 0,04166323 ! mannose metabolic process GO:0006013 9 9 0,000 0,01585014 0,04161567 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01585014 0,04156822 ! receptor clustering GO:0043113 15 9 0,000 0,01585014 0,04152087 ! epithelial cell development GO:0002064 10 9 0,000 0,01585014 0,04147364 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01585014 0,04142651 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01585014 0,04137948 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01585014 0,04133257 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01585014 0,04128576 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01585014 0,04123906 ! motor axon guidance GO:0008045 14 9 0,000 0,01585014 0,04119246 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01585014 0,04114597 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01585014 0,04109958 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01585014 0,04105329 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01585014 0,04100712 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01585014 0,04096104 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01585014 0,04091507 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01585014 0,0408692 ! response to amine stimulus GO:0014075 13 9 0,000 0,01585014 0,04082343 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01585014 0,04077777 ! erythrocyte development GO:0048821 11 9 0,000 0,01585014 0,04073221 ! renal water homeostasis GO:0003091 14 9 0,000 0,01585014 0,04068675 ! postreplication repair GO:0006301 11 9 0,000 0,01585014 0,04064139 ! mRNA cleavage GO:0006379 13 9 0,000 0,01585014 0,04059613 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01585014 0,04055097 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01585014 0,04050592 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01585014 0,04046096 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01585014 0,0404161 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01585014 0,04037135 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01585014 0,04032669 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01585014 0,04028213 ! acid secretion GO:0046717 14 9 0,000 0,01585014 0,04023767 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01585014 0,0401933 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01585014 0,04014904 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01585014 0,04010487 ! purine base metabolic process GO:0006144 18 9 0,000 0,01585014 0,0400608 ! oocyte differentiation GO:0009994 12 9 0,000 0,01585014 0,04001682 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01585014 0,03997294 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01585014 0,03992916 ! spleen development GO:0048536 15 9 0,000 0,01585014 0,03988548 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01585014 0,03984189 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01585014 0,03979839 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01585014 0,03975499 ! detection of calcium ion GO:0005513 13 9 0,000 0,01585014 0,03971168 ! blastocyst formation GO:0001825 12 9 0,000 0,01585014 0,03966847 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01585014 0,03962535 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01585014 0,03958233 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01585014 0,0395394 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01585014 0,03949656 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01585014 0,03945382 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01585014 0,03941116 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01585014 0,0393686 ! prepulse inhibition GO:0060134 14 9 0,000 0,01585014 0,03932613 ! embryonic placenta development GO:0001892 12 9 0,000 0,01585014 0,03928376 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01585014 0,03924147 ! insulin secretion GO:0030073 17 9 0,000 0,01585014 0,03919927 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01585014 0,03915717 ! response to nicotine GO:0035094 16 9 0,000 0,01585014 0,03911516 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01585014 0,03907323 ! nucleus localization GO:0051647 15 9 0,000 0,01585014 0,0390314 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01585014 0,03898965 ! localization within membrane GO:0051668 15 9 0,000 0,01585014 0,038948 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01759619 0,04319235 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01759619 0,0431463 ! neuron fate specification GO:0048665 11 10 0,000 0,01759619 0,04310035 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01759619 0,0430545 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01759619 0,04300875 ! thyroid gland development GO:0030878 19 10 0,000 0,01759619 0,04296309 ! synapsis GO:0007129 13 10 0,000 0,01759619 0,04291753 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01759619 0,04287206 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01759619 0,0428267 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01759619 0,04278143 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01759619 0,04273625 ! sulfate transport GO:0008272 12 10 0,000 0,01759619 0,04269117 ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01759619 0,04264618 ! androgen metabolic process GO:0008209 13 10 0,000 0,01759619 0,04260129 ! phospholipid efflux GO:0033700 16 10 0,000 0,01759619 0,0425565 ! hippocampus development GO:0021766 19 10 0,000 0,01759619 0,0425118 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01759619 0,04246719 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01759619 0,04242267 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01759619 0,04237825 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01759619 0,04233392 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01759619 0,04228969 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,01759619 0,04224554 ! pathogenesis GO:0009405 13 10 0,000 0,01759619 0,04220149 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01759619 0,04215753 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01759619 0,04211366 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01759619 0,04206988 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01759619 0,0420262 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01759619 0,0419826 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,01759619 0,0419391 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01759619 0,04189568 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01759619 0,04185236 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01759619 0,04180912 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01759619 0,04176597 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01759619 0,04172292 ! response to X-ray GO:0010165 16 10 0,000 0,01759619 0,04167995 ! B cell proliferation GO:0042100 14 10 0,000 0,01759619 0,04163707 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01759619 0,04159427 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01759619 0,04155157 ! forebrain cell migration GO:0021885 17 10 0,000 0,01759619 0,04150895 ! lipid digestion GO:0044241 15 10 0,000 0,01759619 0,04146642 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01759619 0,04142398 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01759619 0,04138162 ! UV protection GO:0009650 14 10 0,000 0,01759619 0,04133936 ! entry into host cell GO:0030260 20 10 0,000 0,01759619 0,04129717 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01759619 0,04125508 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01759619 0,04121306 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01759619 0,04117114 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01759619 0,0411293 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01759619 0,04108754 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01759619 0,04104587 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01759619 0,04100428 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01759619 0,04096278 ! regulation of organ growth GO:0046620 11 10 0,000 0,01759619 0,04092136 ! response to dsRNA GO:0043331 18 10 0,000 0,01759619 0,04088003 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01759619 0,04083878 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01759619 0,04079761 ! embryonic axis specification GO:0000578 12 10 0,000 0,01759619 0,04075652 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01759619 0,04071552 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01759619 0,0406746 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01759619 0,04063376 ! cranial nerve development GO:0021545 12 10 0,000 0,01759619 0,04059301 ! fucose catabolic process GO:0019317 16 10 0,000 0,01759619 0,04055233 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01759619 0,04051174 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01759619 0,04047123 ! protein sumoylation GO:0016925 12 10 0,000 0,01759619 0,0404308 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01759619 0,04039045 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01759619 0,04035018 ! zymogen activation GO:0031638 14 10 0,000 0,01759619 0,04030999 ! salivary gland development GO:0007431 22 10 0,000 0,01759619 0,04026988 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01759619 0,04022985 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01759619 0,0401899 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01759619 0,04015003 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01759619 0,04011024 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,01759619 0,04007052 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01759619 0,04003089 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01759619 0,03999133 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01759619 0,03995186 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01759619 0,03991245 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01759619 0,03987313 ! detection of bacterium GO:0016045 10 10 0,000 0,01759619 0,03983389 ! embryonic gut development GO:0048566 11 10 0,000 0,01759619 0,03979472 ! activation of innate immune response GO:0002218 10 10 0,000 0,01759619 0,03975563 GO:0002758|innate immune response-activating signal transduction, ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01759619 0,03971661 ! developmental induction GO:0031128 13 10 0,000 0,01759619 0,03967768 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01759619 0,03963881 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01759619 0,03960003 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01759619 0,03956132 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01759619 0,03952268 ! rRNA transcription GO:0009303 17 11 0,000 0,01933923 0,04339535 ! respiratory burst GO:0045730 14 11 0,000 0,01933923 0,04335306 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01933923 0,04331084 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01933923 0,04326871 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01933923 0,04322666 ! virus-host interaction GO:0019048 17 11 0,000 0,01933923 0,0431847 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,01933923 0,04314281 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,01933923 0,04310101 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,01933923 0,04305928 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01933923 0,04301764 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,01933923 0,04297607 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,01933923 0,04293459 ! mating GO:0007618 14 11 0,000 0,01933923 0,04289319 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01933923 0,04285187 ! T cell proliferation GO:0042098 20 11 0,000 0,01933923 0,04281062 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01933923 0,04276946 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,01933923 0,04272837 ! bone resorption GO:0045453 16 11 0,000 0,01933923 0,04268737 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01933923 0,04264644 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01933923 0,04260559 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01933923 0,04256482 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01933923 0,04252413 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01933923 0,04248351 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01933923 0,04244297 ! syncytium formation GO:0006949 15 11 0,000 0,01933923 0,04240251 ! plasma membrane organization GO:0007009 18 11 0,000 0,01933923 0,04236213 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01933923 0,04232182 ! focal adhesion formation GO:0048041 24 11 0,000 0,01933923 0,04228159 ! mitotic spindle organization GO:0007052 15 11 0,000 0,01933923 0,04224144 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,01933923 0,04220136 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01933923 0,04216136 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01933923 0,04212144 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01933923 0,04208159 ! adult heart development GO:0007512 11 11 0,000 0,01933923 0,04204181 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01933923 0,04200211 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01933923 0,04196249 ! temperature homeostasis GO:0001659 16 11 0,000 0,01933923 0,04192294 ! L-glutamate transport GO:0015813 16 11 0,000 0,01933923 0,04188346 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,01933923 0,04184406 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01933923 0,04180473 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01933923 0,04176548 ! stem cell development GO:0048864 29 11 0,000 0,01933923 0,0417263 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01933923 0,0416872 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01933923 0,04164816 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,01933923 0,0416092 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01933923 0,04157032 ! vasoconstriction GO:0042310 15 11 0,000 0,01933923 0,0415315 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01933923 0,04149276 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01933923 0,04145409 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01933923 0,04141549 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01933923 0,04137697 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,01933923 0,04133851 ! chromatin silencing GO:0006342 19 11 0,000 0,01933923 0,04130013 ! nucleosome positioning GO:0016584 13 11 0,000 0,01933923 0,04126182 ! T cell homeostasis GO:0043029 20 11 0,000 0,01933923 0,04122357 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01933923 0,0411854 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,01933923 0,04114731 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01933923 0,04110928 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01933923 0,04107132 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01933923 0,04103343 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01933923 0,04099561 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01933923 0,04095786 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01933923 0,04092018 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,01933923 0,04088257 ! male genitalia development GO:0030539 13 11 0,000 0,01933923 0,04084503 ! cholesterol efflux GO:0033344 19 11 0,000 0,01933923 0,04080756 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,01933923 0,04077015 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,01933923 0,04073282 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01933923 0,04069555 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01933923 0,04065835 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01933923 0,04062122 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01933923 0,04058416 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01933923 0,04054716 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01933923 0,04051023 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01933923 0,04047337 ! lysogeny GO:0030069 18 11 0,000 0,01933923 0,04043658 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,01933923 0,04039985 ! acrosome reaction GO:0007340 13 11 0,000 0,01933923 0,04036319 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01933923 0,0403266 ! lactation GO:0007595 20 12 0,000 0,02107929 0,04391518 ! reproductive cellular process GO:0048610 14 12 0,000 0,02107929 0,04387544 ! tRNA modification GO:0006400 14 12 0,000 0,02107929 0,04383577 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,02107929 0,04379617 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,02107929 0,04375664 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,02107929 0,04371719 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,02107929 0,0436778 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,02107929 0,04363849 ! non-recombinational repair GO:0000726 19 12 0,000 0,02107929 0,04359925 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,02107929 0,04356007 ! peroxisomal transport GO:0043574 21 12 0,000 0,02107929 0,04352097 ! cartilage condensation GO:0001502 18 12 0,000 0,02107929 0,04348194 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,02107929 0,04344298 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,02107929 0,04340408 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,02107929 0,04336526 ! heart looping GO:0001947 15 12 0,000 0,02107929 0,04332651 ! palate development GO:0060021 15 12 0,000 0,02107929 0,04328782 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,02107929 0,04324921 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,02107929 0,04321066 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,02107929 0,04317218 ! arginine metabolic process GO:0006525 13 12 0,000 0,02107929 0,04313377 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,02107929 0,04309543 ! methionine metabolic process GO:0006555 13 12 0,000 0,02107929 0,04305716 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,02107929 0,04301895 ! Golgi organization GO:0007030 18 12 0,000 0,02107929 0,04298082 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,02107929 0,04294275 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,02107929 0,04290474 ! monoamine transport GO:0015844 13 12 0,000 0,02107929 0,04286681 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02107929 0,04282894 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,02107929 0,04279114 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,02107929 0,04275341 ! L-amino acid transport GO:0015807 20 12 0,000 0,02107929 0,04271574 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,02107929 0,04267814 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,02107929 0,0426406 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,02107929 0,04260313 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02107929 0,04256573 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,02107929 0,04252839 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,02107929 0,04249111 ! cerebellum development GO:0021549 13 12 0,000 0,02107929 0,04245391 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,02107929 0,04241676 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,02107929 0,04237969 ! histone acetylation GO:0016573 23 12 0,000 0,02107929 0,04234267 ! histone methylation GO:0016571 15 12 0,000 0,02107929 0,04230573 ! autonomic nervous system development GO:0048483 23 12 0,000 0,02107929 0,04226884 ! gland morphogenesis GO:0022612 23 12 0,000 0,02107929 0,04223202 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,02107929 0,04219527 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,02107929 0,04215858 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,02107929 0,04212195 ! response to gamma radiation GO:0010332 20 12 0,000 0,02107929 0,04208538 ! regulation of epidermis development GO:0045682 17 12 0,000 0,02107929 0,04204888 ! intestinal absorption GO:0050892 19 12 0,000 0,02107929 0,04201245 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,02107929 0,04197607 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,02107929 0,04193976 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,02107929 0,04190351 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,02107929 0,04186732 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,02107929 0,0418312 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,02107929 0,04179514 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,02107929 0,04175914 ! microspike assembly GO:0030035 23 12 0,000 0,02107929 0,0417232 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,02107929 0,04168733 ! response to cold GO:0009409 14 12 0,000 0,02107929 0,04165151 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,02281635 0,04504516 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,02281635 0,04500653 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02281635 0,04496796 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02281635 0,04492946 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,02281635 0,04489103 ! water transport GO:0006833 17 13 0,000 0,02281635 0,04485266 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02281635 0,04481436 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02281635 0,04477612 ! lipid localization GO:0010876 24 13 0,000 0,02281635 0,04473795 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02281635 0,04469984 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02281635 0,0446618 ! organelle fusion GO:0048284 28 13 0,000 0,02281635 0,04462382 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02281635 0,04458591 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02281635 0,04454806 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,02281635 0,04451027 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02281635 0,04447255 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02281635 0,0444349 ! response to hexose stimulus GO:0009746 19 13 0,000 0,02281635 0,0443973 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,02281635 0,04435977 ! glutamate metabolic process GO:0006536 18 13 0,000 0,02281635 0,04432231 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02281635 0,04428491 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02281635 0,04424757 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02281635 0,04421029 ! NAD metabolic process GO:0019674 21 13 0,000 0,02281635 0,04417308 ! exocrine system development GO:0035272 27 13 0,000 0,02281635 0,04413592 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02281635 0,04409883 ! bone mineralization GO:0030282 15 13 0,000 0,02281635 0,04406181 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02281635 0,04402484 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02281635 0,04398794 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02281635 0,0439511 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02281635 0,04391432 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,02281635 0,0438776 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02281635 0,04384095 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,02281635 0,04380435 ! genitalia development GO:0048806 15 13 0,000 0,02281635 0,04376782 ! regulation of cellular pH GO:0030641 20 13 0,000 0,02281635 0,04373134 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,02281635 0,04369493 ! cellular pigmentation GO:0033059 24 13 0,000 0,02281635 0,04365858 ! tissue regeneration GO:0042246 21 13 0,000 0,02281635 0,04362229 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02281635 0,04358606 ! cofactor transport GO:0051181 19 13 0,000 0,02281635 0,04354989 ! NADP metabolic process GO:0006739 18 13 0,000 0,02281635 0,04351378 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02281635 0,04347772 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02281635 0,04344173 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02281635 0,0434058 ! gas transport GO:0015669 18 13 0,000 0,02281635 0,04336993 ! regulation of RNA stability GO:0043487 28 13 0,000 0,02281635 0,04333412 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02281635 0,04329836 ! regulation of axon extension GO:0030516 23 13 0,000 0,02281635 0,04326267 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,02281635 0,04322703 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02281635 0,04319145 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02281635 0,04315593 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02281635 0,04312047 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02281635 0,04308507 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02281635 0,04304972 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,02455044 0,04628361 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,02455044 0,0462457 ! superoxide anion generation GO:0042554 18 14 0,000 0,02455044 0,04620786 ! neuron maturation GO:0042551 21 14 0,000 0,02455044 0,04617008 ! regulation of S phase GO:0033261 18 14 0,000 0,02455044 0,04613236 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,02455044 0,0460947 ! myotube differentiation GO:0014902 21 14 0,000 0,02455044 0,0460571 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,02455044 0,04601956 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,02455044 0,04598209 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,02455044 0,04594467 ! inositol metabolic process GO:0006020 20 14 0,000 0,02455044 0,04590732 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,02455044 0,04587003 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,02455044 0,0458328 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,02455044 0,04579562 ! gene silencing by RNA GO:0031047 20 14 0,000 0,02455044 0,04575851 ! response to cAMP GO:0051591 19 14 0,000 0,02455044 0,04572146 ! limbic system development GO:0021761 25 14 0,000 0,02455044 0,04568447 ! startle response GO:0001964 21 14 0,000 0,02455044 0,04564754 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,02455044 0,04561067 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,02455044 0,04557385 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,02455044 0,0455371 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,02455044 0,04550041 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,02455044 0,04546377 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,02455044 0,0454272 ! glycine metabolic process GO:0006544 22 14 0,000 0,02455044 0,04539068 ! pituitary gland development GO:0021983 23 14 0,000 0,02455044 0,04535422 ! cellular response to starvation GO:0009267 21 14 0,000 0,02455044 0,04531782 ! lysosomal transport GO:0007041 20 14 0,000 0,02455044 0,04528148 ! regulation of heart rate GO:0002027 23 14 0,000 0,02455044 0,0452452 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,02455044 0,04520897 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,02455044 0,0451728 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,02455044 0,04513669 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,02455044 0,04510064 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,02455044 0,04506465 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,02455044 0,04502871 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,02455044 0,04499283 ! axon cargo transport GO:0008088 27 14 0,000 0,02455044 0,04495701 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,02455044 0,04492124 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,02455044 0,04488554 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,02455044 0,04484988 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,02455044 0,04481429 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02455044 0,04477875 ! mRNA splice site selection GO:0006376 26 14 0,000 0,02455044 0,04474327 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,02455044 0,04470784 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,02455044 0,04467247 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,02455044 0,04463716 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,02455044 0,0446019 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,02455044 0,0445667 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,02455044 0,04453155 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,02455044 0,04449646 ! muscle maintenance GO:0046716 19 14 0,000 0,02455044 0,04446142 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,02455044 0,04442644 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,02455044 0,04439151 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,02455044 0,04435664 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,02455044 0,04432182 ! cell killing GO:0001906 20 14 0,000 0,02455044 0,04428706 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,02455044 0,04425235 ! cilium assembly GO:0042384 20 14 0,000 0,02455044 0,0442177 ! peptide hormone secretion GO:0030072 23 14 0,000 0,02455044 0,0441831 ! metencephalon development GO:0022037 19 15 0,000 0,02628154 0,04726157 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02628154 0,04722464 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,02628154 0,04718778 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,02628154 0,04715097 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,02628154 0,04711422 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,02628154 0,04707753 ! lipid phosphorylation GO:0046834 23 15 0,000 0,02628154 0,04704089 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,02628154 0,04700431 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,02628154 0,04696779 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,02628154 0,04693132 ! bile acid metabolic process GO:0008206 22 15 0,000 0,02628154 0,04689491 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,02628154 0,04685856 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,02628154 0,04682227 ! adult walking behavior GO:0007628 25 15 0,000 0,02628154 0,04678603 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02628154 0,04674984 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,02628154 0,04671371 ! myoblast differentiation GO:0045445 27 15 0,000 0,02628154 0,04667764 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,02628154 0,04664162 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,02628154 0,04660566 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,02628154 0,04656976 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,02628154 0,04653391 ! cerebral cortex development GO:0021987 29 15 0,000 0,02628154 0,04649811 ! response to osmotic stress GO:0006970 22 15 0,000 0,02628154 0,04646237 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,02628154 0,04642669 ! DNA integration GO:0015074 22 15 0,000 0,02628154 0,04639105 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,02628154 0,04635548 ! peptide secretion GO:0002790 27 15 0,000 0,02628154 0,04631996 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,02628154 0,04628449 ! regulation of vasodilation GO:0042312 24 15 0,000 0,02628154 0,04624908 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,02628154 0,04621372 ! neuron recognition GO:0008038 22 15 0,000 0,02628154 0,04617841 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,02628154 0,04614316 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,02628154 0,04610797 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,02628154 0,04607282 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,02628154 0,04603773 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,02628154 0,0460027 ! biomineral formation GO:0031214 18 15 0,000 0,02628154 0,04596771 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,02628154 0,04593278 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,02628154 0,04589791 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,02628154 0,04586308 ! dopamine metabolic process GO:0042417 30 15 0,000 0,02628154 0,04582831 ! organic cation transport GO:0015695 19 15 0,000 0,02628154 0,04579359 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,02628154 0,04575893 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,02628154 0,04572432 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,02628154 0,04568975 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,02628154 0,04565525 ! defense response to virus GO:0051607 27 15 0,000 0,02628154 0,04562079 ! peptide hormone processing GO:0016486 19 15 0,000 0,02628154 0,04558638 ! protein secretion GO:0009306 27 16 0,000 0,02800967 0,04854728 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,02800967 0,04851073 ! hormone secretion GO:0046879 25 16 0,000 0,02800967 0,04847423 ! bone remodeling GO:0046849 24 16 0,000 0,02800967 0,04843778 ! endothelial cell migration GO:0043542 22 16 0,000 0,02800967 0,04840139 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,02800967 0,04836505 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,02800967 0,04832877 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02800967 0,04829254 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,02800967 0,04825636 ! glial cell development GO:0021782 24 16 0,000 0,02800967 0,04822024 ! patterning of blood vessels GO:0001569 24 16 0,000 0,02800967 0,04818418 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,02800967 0,04814817 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,02800967 0,04811221 ! protein polyubiquitination GO:0000209 26 16 0,000 0,02800967 0,0480763 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,02800967 0,04804045 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,02800967 0,04800465 ! fructose metabolic process GO:0006000 20 16 0,000 0,02800967 0,04796891 ! regulation of protein binding GO:0043393 27 16 0,000 0,02800967 0,04793322 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,02800967 0,04789758 ! protein export from nucleus GO:0006611 24 16 0,000 0,02800967 0,047862 ! negative regulation of immune response GO:0050777 28 16 0,000 0,02800967 0,04782646 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,02800967 0,04779098 ! DNA replication initiation GO:0006270 25 16 0,000 0,02800967 0,04775556 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,02800967 0,04772018 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,02800967 0,04768486 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,02800967 0,04764959 ! diencephalon development GO:0021536 25 16 0,000 0,02800967 0,04761437 ! oogenesis GO:0048477 23 16 0,000 0,02800967 0,04757921 ! neural crest cell migration GO:0001755 24 16 0,000 0,02800967 0,04754409 ! G1 phase GO:0051318 27 16 0,000 0,02800967 0,04750903 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,02800967 0,04747402 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02800967 0,04743906 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,02800967 0,04740416 ! steroid catabolic process GO:0006706 22 16 0,000 0,02800967 0,0473693 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02800967 0,04733449 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,02800967 0,04729974 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,02800967 0,04726504 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,02800967 0,04723039 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,02800967 0,04719579 ! sperm-egg recognition GO:0035036 16 16 0,000 0,02800967 0,04716123 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,02800967 0,04712674 ! nerve development GO:0021675 18 16 0,000 0,02800967 0,04709229 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,02800967 0,04705789 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,02800967 0,04702354 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,02973484 0,04988339 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,02973484 0,04984703 ! negative regulation of defense response GO:0031348 19 17 0,000 0,02973484 0,04981072 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,02973484 0,04977447 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,02973484 0,04973827 ! glycerol metabolic process GO:0006071 20 17 0,000 0,02973484 0,04970212 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,02973484 0,04966603 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,02973484 0,04962999 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02973484 0,049594 ! signal complex assembly GO:0007172 29 17 0,000 0,02973484 0,04955806 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,02973484 0,04952217 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,02973484 0,04948634 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,02973484 0,04945056 ! memory GO:0007613 25 17 0,000 0,02973484 0,04941483 ! keratinization GO:0031424 17 17 0,000 0,02973484 0,04937915 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,02973484 0,04934352 ! retinoid metabolic process GO:0001523 22 17 0,000 0,02973484 0,04930795 GO:0016101|diterpenoid metabolic process, ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,02973484 0,04927242 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,02973484 0,04923695 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,02973484 0,04920153 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,02973484 0,04916616 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,02973484 0,04913083 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,02973484 0,04909557 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,02973484 0,04906035 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,02973484 0,04902518 ! heme metabolic process GO:0042168 27 17 0,000 0,02973484 0,04899006 ! actin filament bundle formation GO:0051017 26 17 0,000 0,02973484 0,04895499 ! neuromuscular junction development GO:0007528 23 17 0,000 0,02973484 0,04891997 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,02973484 0,04888501 ! body fluid secretion GO:0007589 27 17 0,000 0,02973484 0,04885009 ! stem cell differentiation GO:0048863 36 17 0,000 0,02973484 0,04881522 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02973484 0,0487804 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,02973484 0,04874563 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,02973484 0,04871091 ! sensory perception of pain GO:0019233 23 17 0,000 0,02973484 0,04867624 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,02973484 0,04864162 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,02973484 0,04860705 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,02973484 0,04857253 ! synaptogenesis GO:0007416 24 17 0,000 0,02973484 0,04853806 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,02973484 0,04850363 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02973484 0,04846926 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,02973484 0,04843493 ! cell-cell junction organization GO:0045216 25 17 0,000 0,02973484 0,04840065 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,02973484 0,04836642 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,02973484 0,04833224 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,02973484 0,04829811 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,02973484 0,04826402 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,02973484 0,04822999 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,02973484 0,048196 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,03145704 0,05095154 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,03145704 0,05091568 ! positive regulation of translation GO:0045727 28 18 0,000 0,03145704 0,05087987 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,03145704 0,05084412 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,03145704 0,05080841 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,03145704 0,05077276 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,03145704 0,05073715 ! cAMP metabolic process GO:0046058 33 18 0,000 0,03145704 0,0507016 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,03145704 0,05066609 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,03145704 0,05063064 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,03145704 0,05059523 ! axis specification GO:0009798 26 18 0,000 0,03145704 0,05055988 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,03145704 0,05052457 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,03145704 0,05048931 ! pancreas development GO:0031016 26 18 0,000 0,03145704 0,0504541 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,03145704 0,05041894 ! glutamine metabolic process GO:0006541 23 18 0,000 0,03145704 0,05038383 ! response to retinoic acid GO:0032526 25 18 0,000 0,03145704 0,05034877 ! pigmentation during development GO:0048066 31 18 0,000 0,03145704 0,05031376 ! central nervous system neuron development GO:0021954 30 18 0,000 0,03145704 0,05027879 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,03145704 0,05024388 ! fucose metabolic process GO:0006004 26 18 0,000 0,03145704 0,05020901 ! response to fungus GO:0009620 19 18 0,000 0,03145704 0,05017419 ! peptide cross-linking GO:0018149 31 18 0,000 0,03145704 0,05013942 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,03145704 0,0501047 ! heart process GO:0003015 27 18 0,000 0,03145704 0,05007002 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,03145704 0,0500354 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,03145704 0,05000082 ! visual learning GO:0008542 35 18 0,000 0,03145704 0,04996629 ! somitogenesis GO:0001756 24 18 0,000 0,03145704 0,0499318 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,03145704 0,04989737 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,03145704 0,04986298 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,03145704 0,04982864 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,03145704 0,04979434 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,03145704 0,0497601 ! vitamin transport GO:0051180 24 18 0,000 0,03145704 0,0497259 ! hormone transport GO:0009914 27 18 0,000 0,03145704 0,04969175 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,03145704 0,04965764 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,03145704 0,04962358 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,03145704 0,04958957 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,03145704 0,0495556 ! cell-cell recognition GO:0009988 20 18 0,000 0,03145704 0,04952169 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,03145704 0,04948781 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,03145704 0,04945399 ! regulation of glucose import GO:0046324 21 18 0,000 0,03145704 0,04942021 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,03145704 0,04938647 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,03145704 0,04935278 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,03145704 0,04931914 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,03145704 0,04928555 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,03317628 0,0519438 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,03317628 0,05190846 ! positive regulation of ossification GO:0045778 30 19 0,000 0,03317628 0,05187317 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,03317628 0,05183793 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,03317628 0,05180274 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,03317628 0,0517676 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,03317628 0,0517325 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,03317628 0,05169745 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,03317628 0,05166245 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,03317628 0,05162749 ! regeneration GO:0031099 32 19 0,000 0,03317628 0,05159259 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,03317628 0,05155773 ! response to alkaloid GO:0043279 32 19 0,000 0,03317628 0,05152292 ! sensory perception of taste GO:0050909 23 19 0,000 0,03317628 0,05148815 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,03317628 0,05145343 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,03317628 0,05141876 ! smooth muscle contraction GO:0006939 36 19 0,000 0,03317628 0,05138413 ! peroxisome organization GO:0007031 29 19 0,000 0,03317628 0,05134955 ! digestive system process GO:0022600 30 19 0,000 0,03317628 0,05131502 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,03317628 0,05128054 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,03317628 0,0512461 ! response to vitamin A GO:0033189 26 19 0,000 0,03317628 0,0512117 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,03317628 0,05117736 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,03317628 0,05114305 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,03317628 0,0511088 ! response to starvation GO:0042594 30 19 0,000 0,03317628 0,05107459 ! sex determination GO:0007530 29 19 0,000 0,03317628 0,05104043 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,03317628 0,05100631 ! plasma membrane fusion GO:0045026 23 19 0,000 0,03317628 0,05097224 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,03317628 0,05093821 ! cytolysis GO:0019835 20 19 0,000 0,03317628 0,05090423 ! renal system process GO:0003014 35 19 0,000 0,03317628 0,05087029 ! vasodilation GO:0042311 33 19 0,000 0,03317628 0,0508364 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,03317628 0,05080255 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,03317628 0,05076875 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,03317628 0,050735 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,03317628 0,05070129 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,03317628 0,05066762 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,03317628 0,050634 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,03317628 0,05060042 ! sarcomere organization GO:0045214 23 19 0,000 0,03317628 0,05056689 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,03317628 0,0505334 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,03317628 0,05049996 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,03317628 0,05046656 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,03317628 0,0504332 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,03317628 0,05039989 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,03317628 0,05036663 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,03317628 0,0503334 ! protein stabilization GO:0050821 26 19 0,000 0,03317628 0,05030022 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,03489256 0,05286752 ! iron ion transport GO:0006826 37 20 0,000 0,03489256 0,05283272 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,03489256 0,05279796 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,03489256 0,05276325 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,03489256 0,05272858 ! response to vitamin GO:0033273 29 20 0,000 0,03489256 0,05269396 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,03489256 0,05265938 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,03489256 0,05262485 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,03489256 0,05259037 ! spinal cord development GO:0021510 31 20 0,000 0,03489256 0,05255593 ! response to ethanol GO:0045471 37 20 0,000 0,03489256 0,05252153 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,03489256 0,05248718 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,03489256 0,05245288 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,03489256 0,05241861 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,03489256 0,0523844 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,03489256 0,05235023 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,03489256 0,0523161 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,03489256 0,05228202 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,03489256 0,05224798 ! pallium development GO:0021543 38 20 0,000 0,03489256 0,05221399 ! DNA modification GO:0006304 28 20 0,000 0,03489256 0,05218004 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,03489256 0,05214613 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,03489256 0,05211227 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,03489256 0,05207846 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,03489256 0,05204468 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,03489256 0,05201095 ! collagen catabolic process GO:0030574 25 20 0,000 0,03489256 0,05197727 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,03489256 0,05194362 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,03489256 0,05191003 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,03489256 0,05187647 ! alditol metabolic process GO:0019400 24 20 0,000 0,03489256 0,05184296 ! actin filament-based movement GO:0030048 34 20 0,000 0,03489256 0,05180949 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,0366059 0,05431844 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,0366059 0,05428342 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,0366059 0,05424844 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,0366059 0,05421351 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,0366059 0,05417862 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,0366059 0,05414378 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,0366059 0,05410898 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,0366059 0,05407423 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,0366059 0,05403952 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,0366059 0,05400486 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,0366059 0,05397024 ! protein amino acid acylation GO:0043543 37 21 0,000 0,0366059 0,05393567 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,0366059 0,05390114 ! vesicle docking GO:0048278 27 21 0,000 0,0366059 0,05386665 ! phototransduction GO:0007602 25 21 0,000 0,0366059 0,05383221 ! dendrite development GO:0016358 35 21 0,000 0,0366059 0,05379781 ! visual behavior GO:0007632 39 21 0,000 0,0366059 0,05376346 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,0366059 0,05372915 ! ovarian follicle development GO:0001541 30 21 0,000 0,0366059 0,05369488 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,0366059 0,05366066 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,0366059 0,05362648 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,0366059 0,05359235 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,0366059 0,05355826 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,0366059 0,05352421 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,0366059 0,0534902 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,0366059 0,05345624 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,0366059 0,05342232 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,0366059 0,05338845 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,0366059 0,05335461 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,0366059 0,05332082 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,0366059 0,05328708 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,0366059 0,05325337 ! fatty acid transport GO:0015908 30 21 0,000 0,0366059 0,05321971 ! immunoglobulin production GO:0002377 33 21 0,000 0,0366059 0,05318609 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,0366059 0,05315251 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,0366059 0,05311898 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,0366059 0,05308549 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,0366059 0,05305204 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,0366059 0,05301863 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,0366059 0,05298526 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,0366059 0,05295194 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,0366059 0,05291865 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,0366059 0,05288541 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,0366059 0,05285222 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,0366059 0,05281906 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,0366059 0,05278594 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,0366059 0,05275287 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,0383163 0,05518315 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,0383163 0,05514862 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,0383163 0,05511413 ! viral genome replication GO:0019079 29 22 0,000 0,0383163 0,05507968 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,0383163 0,05504528 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,0383163 0,05501092 ! leukocyte adhesion GO:0007159 38 22 0,000 0,0383163 0,0549766 ! molting cycle process GO:0022404 40 22 0,000 0,0383163 0,05494233 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,0383163 0,05490809 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,0383163 0,0548739 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,0383163 0,05483976 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,0383163 0,05480565 ! vasculogenesis GO:0001570 33 22 0,000 0,0383163 0,05477159 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,0383163 0,05473757 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,0383163 0,05470359 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,0383163 0,05466966 ! lysosome organization GO:0007040 37 22 0,000 0,0383163 0,05463577 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,0383163 0,05460191 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,0383163 0,0545681 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,0383163 0,05453434 ! regulation of behavior GO:0050795 38 22 0,000 0,0383163 0,05450061 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,0383163 0,05446693 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,0383163 0,05443329 ! membrane depolarization GO:0051899 35 22 0,000 0,0383163 0,05439968 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,0383163 0,05436613 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,0383163 0,05433261 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,0383163 0,05429913 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,0383163 0,0542657 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,0383163 0,0542323 ! blastocyst development GO:0001824 37 22 0,000 0,0383163 0,05419895 ! neural tube closure GO:0001843 33 22 0,000 0,0383163 0,05416564 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,0383163 0,05413236 ! protein tetramerization GO:0051262 39 22 0,000 0,0383163 0,05409913 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,04002376 0,05647524 ! neuron fate commitment GO:0048663 32 23 0,000 0,04002376 0,05644061 ! embryonic pattern specification GO:0009880 31 23 0,000 0,04002376 0,05640603 ! myelination GO:0042552 35 23 0,000 0,04002376 0,05637149 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,04002376 0,05633699 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,04002376 0,05630253 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,04002376 0,05626812 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,04002376 0,05623374 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,04002376 0,05619941 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,04002376 0,05616513 ! osteoblast differentiation GO:0001649 40 23 0,000 0,04002376 0,05613088 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,04002376 0,05609667 ! interaction with host GO:0051701 37 23 0,000 0,04002376 0,05606251 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,04002376 0,05602839 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,04002376 0,05599431 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,04002376 0,05596027 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,04002376 0,05592627 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,04002376 0,05589231 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,04002376 0,0558584 ! cell fate determination GO:0001709 45 23 0,000 0,04002376 0,05582452 ! pentose metabolic process GO:0019321 31 23 0,000 0,04002376 0,05579069 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,04002376 0,0557569 ! spermatid development GO:0007286 33 23 0,000 0,04002376 0,05572315 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,04002376 0,05568944 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,04002376 0,05565577 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,04002376 0,05562214 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,04002376 0,05558855 ! telomere organization GO:0032200 32 23 0,000 0,04002376 0,055555 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,04002376 0,0555215 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,04002376 0,05548803 ! regulation of amine transport GO:0051952 38 23 0,000 0,04002376 0,0554546 ! liver development GO:0001889 40 23 0,000 0,04002376 0,05542122 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,04172828 0,05774672 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,04172828 0,05771199 ! initiation of viral infection GO:0019059 42 24 0,000 0,04172828 0,05767731 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,04172828 0,05764267 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,04172828 0,05760807 ! superoxide metabolic process GO:0006801 32 24 0,000 0,04172828 0,05757351 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,04172828 0,05753899 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,04172828 0,05750452 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,04172828 0,05747009 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,04172828 0,05743569 ! sperm motility GO:0030317 27 24 0,000 0,04172828 0,05740134 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,04172828 0,05736703 ! vacuole organization GO:0007033 39 24 0,000 0,04172828 0,05733276 ! receptor metabolic process GO:0043112 37 24 0,000 0,04172828 0,05729853 ! neural crest cell development GO:0014032 39 24 0,000 0,04172828 0,05726435 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,04172828 0,0572302 ! primary neural tube formation GO:0014020 35 24 0,000 0,04172828 0,05719609 ! negative regulation of cell development GO:0010721 56 24 0,000 0,04172828 0,05716203 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,04172828 0,057128 ! base-excision repair GO:0006284 31 24 0,000 0,04172828 0,05709402 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,04172828 0,05706007 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,04172828 0,05702617 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,04172828 0,05699231 ! glutathione metabolic process GO:0006749 29 24 0,000 0,04172828 0,05695848 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,04172828 0,0569247 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,04172828 0,05689096 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,04172828 0,05685725 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,04342987 0,05914074 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,04342987 0,05910574 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,04342987 0,05907079 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,04342987 0,05903588 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,04342987 0,05900101 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,04342987 0,05896618 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,04342987 0,05893139 ! peptide transport GO:0015833 43 25 0,000 0,04342987 0,05889664 ! male gonad development GO:0008584 33 25 0,000 0,04342987 0,05886194 ! iron ion homeostasis GO:0055072 39 25 0,000 0,04342987 0,05882727 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,04342987 0,05879265 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,04342987 0,05875806 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,04342987 0,05872352 ! phospholipid transport GO:0015914 35 25 0,000 0,04342987 0,05868902 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,04342987 0,05865456 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,04342987 0,05862013 ! detection of light stimulus GO:0009583 30 25 0,000 0,04342987 0,05858575 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,04342987 0,05855141 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,04342987 0,05851711 ! leukocyte proliferation GO:0070661 39 25 0,000 0,04342987 0,05848285 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,04342987 0,05844863 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,04512854 0,06069921 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,04512854 0,06066373 ! translational initiation GO:0006413 43 26 0,000 0,04512854 0,0606283 ! regulation of pH GO:0006885 36 26 0,000 0,04512854 0,06059291 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,04512854 0,06055755 ! circadian rhythm GO:0007623 42 26 0,000 0,04512854 0,06052224 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,04512854 0,06048697 ! post-embryonic development GO:0009791 42 26 0,000 0,04512854 0,06045175 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,04512854 0,06041656 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,04512854 0,06038141 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,04512854 0,06034631 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,04512854 0,06031124 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,04512854 0,06027622 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,04512854 0,06024123 ! regulation of coagulation GO:0050818 39 26 0,000 0,04512854 0,06020629 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,04682429 0,06243239 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,04682429 0,06239622 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,04682429 0,06236009 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,04682429 0,062324 ! membrane docking GO:0022406 39 27 0,000 0,04682429 0,06228795 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,04682429 0,06225195 ! catechol metabolic process GO:0009712 43 27 0,000 0,04682429 0,06221599 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,04682429 0,06218007 ! acute-phase response GO:0006953 42 27 0,000 0,04682429 0,06214419 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,04682429 0,06210835 ! myofibril assembly GO:0030239 36 27 0,000 0,04682429 0,06207255 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,04682429 0,06203679 ! response to ionizing radiation GO:0010212 47 27 0,000 0,04682429 0,06200108 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,04682429 0,0619654 ! natural killer cell activation GO:0030101 35 27 0,000 0,04682429 0,06192977 ! lipid oxidation GO:0034440 38 27 0,000 0,04682429 0,06189418 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,04682429 0,06185863 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,04682429 0,06182312 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,04682429 0,06178765 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,04682429 0,06175222 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,04682429 0,06171683 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,04682429 0,06168149 ! gene silencing GO:0016458 41 27 0,000 0,04682429 0,06164618 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,04851713 0,06383833 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,04851713 0,06380183 ! phenol metabolic process GO:0018958 44 28 0,000 0,04851713 0,06376537 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,04851713 0,06372895 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,04851713 0,06369258 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,04851713 0,06365624 ! cell junction assembly GO:0034329 56 28 0,000 0,04851713 0,06361995 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,04851713 0,0635837 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,04851713 0,06354749 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,04851713 0,06351132 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,04851713 0,0634752 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,04851713 0,06343911 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,04851713 0,06340307 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,04851713 0,06336706 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,04851713 0,0633311 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,04851713 0,06329518 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,04851713 0,06325929 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,04851713 0,06322345 ! mesoderm formation GO:0001707 46 28 0,000 0,04851713 0,06318765 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,04851713 0,06315189 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,04851713 0,06311617 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,04851713 0,06308049 ! ensheathment of neurons GO:0007272 43 28 0,000 0,04851713 0,06304486 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,04851713 0,06300926 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,04851713 0,0629737 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,04851713 0,06293818 ! neural tube formation GO:0001841 41 28 0,000 0,04851713 0,0629027 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,04851713 0,06286726 ! placenta development GO:0001890 37 28 0,000 0,04851713 0,06283187 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,05020705 0,06498381 ! regulation of innate immune response GO:0045088 38 29 0,000 0,05020705 0,06494726 ! ovulation cycle process GO:0022602 41 29 0,000 0,05020705 0,06491075 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,05020705 0,06487428 ! protein targeting to membrane GO:0006612 53 29 0,000 0,05020705 0,06483786 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,05020705 0,06480147 ! mismatch repair GO:0006298 34 29 0,000 0,05020705 0,06476513 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,05020705 0,06472883 ! muscle cell development GO:0055001 38 29 0,000 0,05020705 0,06469256 ! formation of primary germ layer GO:0001704 48 29 0,000 0,05020705 0,06465634 ! telencephalon development GO:0021537 52 29 0,000 0,05020705 0,06462016 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,05020705 0,06458402 ! eye morphogenesis GO:0048592 51 29 0,000 0,05020705 0,06454792 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,05020705 0,06451186 ! tissue homeostasis GO:0001894 42 29 0,000 0,05020705 0,06447584 GO:0048871|multicellular organismal homeostasis, ! collagen metabolic process GO:0032963 40 30 0,000 0,05189408 0,06660512 ! organic anion transport GO:0015711 51 30 0,000 0,05189408 0,06656797 ! cholesterol transport GO:0030301 46 30 0,000 0,05189408 0,06653087 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,05189408 0,0664938 ! spliceosome assembly GO:0000245 49 30 0,000 0,05189408 0,06645678 ! spindle organization GO:0007051 37 30 0,000 0,05189408 0,0664198 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,05189408 0,06638286 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,05189408 0,06634596 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,05189408 0,0663091 ! ceramide metabolic process GO:0006672 43 30 0,000 0,05189408 0,06627228 ! ovulation cycle GO:0042698 43 30 0,000 0,05189408 0,0662355 ! hindbrain development GO:0030902 45 30 0,000 0,05189408 0,06619877 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,05189408 0,06616207 ! adult locomotory behavior GO:0008344 47 30 0,000 0,05189408 0,06612541 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,05189408 0,0660888 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,05189408 0,06605223 ! response to heat GO:0009408 41 30 0,000 0,05189408 0,06601569 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,05189408 0,0659792 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,0535782 0,06808279 ! negative regulation of secretion GO:0051048 49 31 0,000 0,0535782 0,0680452 ! mammary gland development GO:0030879 57 31 0,000 0,0535782 0,06800765 ! glial cell differentiation GO:0010001 55 31 0,000 0,0535782 0,06797013 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,0535782 0,06793266 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,0535782 0,06789524 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,0535782 0,06785785 ! odontogenesis GO:0042476 50 31 0,000 0,0535782 0,0678205 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,0535782 0,0677832 ! segmentation GO:0035282 41 31 0,000 0,0535782 0,06774593 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,0535782 0,06770871 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,0535782 0,06767153 ! metanephros development GO:0001656 58 31 0,000 0,0535782 0,06763439 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,0535782 0,06759729 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,0535782 0,06756023 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,0535782 0,06752321 ! cell fate specification GO:0001708 37 31 0,000 0,0535782 0,06748623 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,0535782 0,06744929 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,0535782 0,06741239 ! RNA modification GO:0009451 40 31 0,000 0,0535782 0,06737553 ! regulation of muscle development GO:0048634 48 32 0,000 0,05525942 0,06945173 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,05525942 0,0694138 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,05525942 0,06937591 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,05525942 0,06933806 ! meiosis I GO:0007127 52 32 0,000 0,05525942 0,06930026 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,05525942 0,06926249 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,05525942 0,06922477 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,05525942 0,06918708 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,05525942 0,06914944 ! peripheral nervous system development GO:0007422 53 32 0,000 0,05525942 0,06911184 ! regulation of protein stability GO:0031647 48 32 0,000 0,05525942 0,06907428 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,05525942 0,06903676 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,05525942 0,06899928 ! cytokine production GO:0001816 44 32 0,000 0,05525942 0,06896184 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,05525942 0,06892444 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,05525942 0,06888709 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,05693776 0,07094087 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,05693776 0,07090246 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,05693776 0,07086409 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,05693776 0,07082577 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,05693776 0,07078748 ! sister chromatid segregation GO:0000819 46 33 0,000 0,05693776 0,07074924 ! ear morphogenesis GO:0042471 42 33 0,000 0,05693776 0,07071104 ! actomyosin structure organization GO:0031032 43 33 0,000 0,05693776 0,07067288 ! cell junction organization GO:0034330 63 33 0,000 0,05693776 0,07063476 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,05693776 0,07059668 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,05693776 0,07055864 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,05693776 0,07052065 GO:0042593|glucose homeostasis, ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,05693776 0,07048269 ! female gonad development GO:0008585 49 33 0,000 0,05693776 0,07044478 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,05693776 0,07040691 ! positive regulation of cell development GO:0010720 54 33 0,000 0,05693776 0,07036907 ! lipid homeostasis GO:0055088 55 33 0,000 0,05693776 0,07033128 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,05693776 0,07029353 ! regulation of proteolysis GO:0030162 50 33 0,000 0,05693776 0,07025582 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,05693776 0,07021815 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,05693776 0,07018052 ! cytokinesis GO:0000910 52 33 0,000 0,05693776 0,07014293 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,05693776 0,07010538 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,05861321 0,07212968 ! mRNA catabolic process GO:0006402 48 34 0,000 0,05861321 0,07209111 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,05861321 0,07205258 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,05861321 0,07201409 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,05861321 0,07197564 ! feeding behavior GO:0007631 45 34 0,000 0,05861321 0,07193724 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,05861321 0,07189887 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,05861321 0,07186054 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,05861321 0,07182226 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,05861321 0,07178402 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,05861321 0,07174581 ! neuron migration GO:0001764 46 34 0,000 0,05861321 0,07170765 ! female gamete generation GO:0007292 43 34 0,000 0,05861321 0,07166953 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,05861321 0,07163145 ! polyol metabolic process GO:0019751 44 34 0,000 0,05861321 0,0715934 ! aerobic respiration GO:0009060 47 34 0,000 0,05861321 0,0715554 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,05861321 0,07151744 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,05861321 0,07147952 ! embryonic organ development GO:0048568 45 34 0,000 0,05861321 0,07144164 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,05861321 0,0714038 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,06028578 0,07340248 ! Notch signaling pathway GO:0007219 56 35 0,000 0,06028578 0,07336365 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,06028578 0,07332485 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,06028578 0,07328609 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,06028578 0,07324738 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,06028578 0,07320871 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,06028578 0,07317007 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,06028578 0,07313148 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,06028578 0,07309293 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,06028578 0,07305442 ! glycogen metabolic process GO:0005977 48 35 0,000 0,06028578 0,07301595 ! pigment metabolic process GO:0042440 61 35 0,000 0,06028578 0,07297752 ! protein homooligomerization GO:0051260 52 35 0,000 0,06028578 0,07293913 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,06195547 0,07491987 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,06195547 0,0748805 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,06195547 0,07484117 ! negative regulation of binding GO:0051100 58 36 0,000 0,06195547 0,07480188 ! organic ether metabolic process GO:0018904 46 36 0,000 0,06195547 0,07476264 ! tissue remodeling GO:0048771 62 36 0,000 0,06195547 0,07472343 ! neural tube development GO:0021915 50 36 0,000 0,06195547 0,07468427 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,06195547 0,07464515 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,06195547 0,07460607 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,06195547 0,07456702 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,06195547 0,07452803 ! glucan metabolic process GO:0044042 49 36 0,000 0,06195547 0,07448907 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,06362229 0,07645312 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,06362229 0,0764132 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,06362229 0,07637332 ! learning GO:0007612 67 37 0,000 0,06362229 0,07633348 ! ion transmembrane transport GO:0034220 56 37 0,000 0,06362229 0,07629368 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,06362229 0,07625392 ! regulation of protein secretion GO:0050708 51 37 0,000 0,06362229 0,07621421 ! amino acid activation GO:0043038 52 37 0,000 0,06362229 0,07617453 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,06362229 0,0761349 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,06528625 0,07808548 ! gliogenesis GO:0042063 71 38 0,000 0,06528625 0,07804489 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,06528625 0,07800435 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,06528625 0,07796385 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,06528625 0,07792339 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,06528625 0,07788297 ! phagocytosis GO:0006909 60 38 0,000 0,06528625 0,0778426 ! mesenchymal cell development GO:0014031 64 38 0,000 0,06528625 0,07780227 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,06528625 0,07776198 ! maintenance of location in cell GO:0051651 69 38 0,000 0,06528625 0,07772173 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,06694734 0,07965799 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,06694734 0,0796168 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,06694734 0,07957565 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,06694734 0,07953455 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,06694734 0,07949349 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,06694734 0,07945247 ! male sex differentiation GO:0046661 53 39 0,000 0,06694734 0,0794115 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,06694734 0,07937056 ! chromatin remodeling GO:0006338 68 39 0,000 0,06694734 0,07932967 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,06694734 0,07928882 ! JNK cascade GO:0007254 54 39 0,000 0,06694734 0,07924801 ! developmental growth GO:0048589 62 39 0,000 0,06694734 0,07920725 ! cell growth GO:0016049 61 39 0,000 0,06694734 0,07916652 ! synapse organization GO:0050808 55 39 0,000 0,06694734 0,07912584 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,06860558 0,08104409 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,06860558 0,08100248 ! regulation of tube size GO:0035150 60 40 0,000 0,06860558 0,08096092 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,06860558 0,0809194 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,06860558 0,08087793 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,06860558 0,08083649 ! peptide metabolic process GO:0006518 56 40 0,000 0,06860558 0,0807951 ! inner ear development GO:0048839 57 40 0,000 0,06860558 0,08075375 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,06860558 0,08071245 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,06860558 0,08067118 ! double-strand break repair GO:0006302 67 40 0,000 0,06860558 0,08062996 ! B cell differentiation GO:0030183 62 40 0,000 0,06860558 0,08058878 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,06860558 0,08054764 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,06860558 0,08050655 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,06860558 0,0804655 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,07026097 0,08236505 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,07026097 0,08232309 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,07026097 0,08228117 ! glucose transport GO:0015758 52 41 0,000 0,07026097 0,0822393 ! endosome transport GO:0016197 71 41 0,000 0,07026097 0,08219747 ! striated muscle contraction GO:0006941 62 41 0,000 0,07026097 0,08215568 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,07026097 0,08211393 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,07026097 0,08207223 ! biopolymer methylation GO:0043414 62 41 0,000 0,07026097 0,08203057 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,07026097 0,08198895 ! mitochondrial transport GO:0006839 60 42 0,000 0,0719135 0,08387478 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,0719135 0,08383226 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,0719135 0,0837898 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,0719135 0,08374737 ! cellular component disassembly GO:0022411 64 42 0,000 0,0719135 0,08370499 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,0719135 0,08366265 ! hexose transport GO:0008645 54 42 0,000 0,0719135 0,08362035 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,0719135 0,0835781 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,0719135 0,08353589 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,0719135 0,08349372 ! excretion GO:0007588 63 42 0,000 0,0719135 0,08345159 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,0719135 0,08340951 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,0719135 0,08336747 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,0719135 0,08332547 ! regulation of cell shape GO:0008360 78 42 0,000 0,0719135 0,08328351 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,0735632 0,08515116 ! leukocyte migration GO:0050900 60 43 0,000 0,0735632 0,08510833 ! neuromuscular process GO:0050905 79 43 0,000 0,0735632 0,08506554 ! activation of caspase activity GO:0006919 65 43 0,000 0,0735632 0,08502279 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,0735632 0,08498009 ! tRNA processing GO:0008033 49 43 0,000 0,0735632 0,08493743 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,0735632 0,08489481 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,0735632 0,08485224 ! methylation GO:0032259 64 43 0,000 0,0735632 0,0848097 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,07521006 0,08666489 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,07521006 0,0866215 ! glycolysis GO:0006096 53 44 0,000 0,07521006 0,08657814 ! regulation of action potential GO:0001508 71 44 0,000 0,07521006 0,08653483 ! regulation of ion transport GO:0043269 57 44 0,000 0,07521006 0,08649156 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,07521006 0,08644834 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,07521006 0,08640516 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,07521006 0,08636202 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,07521006 0,08631893 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,07521006 0,08627587 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,07521006 0,08623287 ! RNA catabolic process GO:0006401 64 45 0,000 0,07685408 0,08807393 ! positive regulation of defense response GO:0031349 59 45 0,000 0,07685408 0,08803007 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,07685408 0,08798625 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,07685408 0,08794248 ! cell recognition GO:0008037 58 45 0,000 0,07685408 0,08789875 ! cell maturation GO:0048469 60 45 0,000 0,07685408 0,08785506 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,07685408 0,08781142 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,07849528 0,08964207 ! cell redox homeostasis GO:0045454 63 46 0,000 0,07849528 0,08959758 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,07849528 0,08955314 ! regulation of ossification GO:0030278 71 46 0,000 0,07849528 0,08950874 ! histone modification GO:0016570 68 46 0,000 0,07849528 0,08946439 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,07849528 0,08942008 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,08013365 0,09124128 ! viral infectious cycle GO:0019058 71 47 0,000 0,08013365 0,09119613 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,08013365 0,09115103 ! endocrine system development GO:0035270 83 47 0,000 0,08013365 0,09110597 ! covalent chromatin modification GO:0016569 75 47 0,000 0,08013365 0,09106096 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,08013365 0,09101599 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,08013365 0,09097107 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,08013365 0,09092619 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,08013365 0,09088135 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,08013365 0,09083656 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,08013365 0,09079182 ! chloride transport GO:0006821 67 48 0,000 0,0817692 0,09259929 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,0817692 0,09255372 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,0817692 0,09250819 ! response to temperature stimulus GO:0009266 62 48 0,000 0,0817692 0,09246271 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,0817692 0,09241728 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,0817692 0,09237189 ! gastrulation GO:0007369 73 48 0,000 0,0817692 0,09232654 ! heart morphogenesis GO:0003007 65 48 0,000 0,0817692 0,09228124 ! regulation of DNA replication GO:0006275 75 48 0,000 0,0817692 0,09223598 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,0817692 0,09219076 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,0817692 0,09214559 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,0817692 0,09210047 ! regulation of endocytosis GO:0030100 63 48 0,000 0,0817692 0,09205539 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,0817692 0,09201035 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,0817692 0,09196536 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,08340194 0,09375584 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,08340194 0,09371004 ! sensory perception of smell GO:0007608 61 49 0,000 0,08340194 0,09366428 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,08340194 0,09361857 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,08340194 0,09357291 ! RNA elongation GO:0006354 62 49 0,000 0,08340194 0,09352728 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,08340194 0,0934817 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,08340194 0,09343617 ! germ cell development GO:0007281 68 49 0,000 0,08340194 0,09339068 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,08340194 0,09334523 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,08340194 0,09329983 ! cartilage development GO:0051216 70 49 0,000 0,08340194 0,09325448 ! maintenance of location GO:0051235 84 49 0,000 0,08340194 0,09320916 ! regulation of actin filament length GO:0030832 72 50 0,000 0,08503187 0,0949846 ! ear development GO:0043583 72 50 0,000 0,08503187 0,09493849 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,08503187 0,09489243 ! membrane fusion GO:0006944 80 50 0,000 0,08503187 0,09484641 ! lipid modification GO:0030258 73 50 0,000 0,08503187 0,09480043 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,08503187 0,0947545 ! proton transport GO:0015992 75 50 0,000 0,08503187 0,09470862 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,08503187 0,09466277 ! positive regulation of secretion GO:0051047 71 51 0,000 0,08665899 0,09642752 ! hydrogen transport GO:0006818 77 51 0,000 0,08665899 0,09638089 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,08665899 0,0963343 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,08665899 0,09628777 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,08665899 0,09624127 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,08665899 0,09619482 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,08665899 0,09614842 ! adult behavior GO:0030534 80 51 0,000 0,08665899 0,09610206 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,08665899 0,09605575 ! transition metal ion transport GO:0000041 74 52 0,000 0,08828331 0,09780906 ! regulation of cellular component size GO:0032535 74 52 0,000 0,08828331 0,09776197 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,08828331 0,09771493 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,08828331 0,09766793 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,08828331 0,09762097 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,08990484 0,09936623 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,08990484 0,09931851 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,08990484 0,09927083 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,08990484 0,09922319 ! kidney development GO:0001822 90 53 0,000 0,08990484 0,0991756 ! single fertilization GO:0007338 59 53 0,000 0,08990484 0,09912806 ! cell projection assembly GO:0030031 76 53 0,000 0,08990484 0,09908056 ! amino acid transport GO:0006865 84 54 0,000 0,09152357 0,1008162 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,09152357 0,10076794 ! regulation of mitosis GO:0007088 84 54 0,000 0,09152357 0,10071972 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,09152357 0,10067156 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,09152357 0,10062343 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,09152357 0,10057536 ! DNA catabolic process GO:0006308 67 54 0,000 0,09152357 0,10052733 ! detection of external stimulus GO:0009581 66 54 0,000 0,09152357 0,10047934 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,09152357 0,1004314 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,09152357 0,10038351 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,09152357 0,10033566 ! exocytosis GO:0006887 74 55 0,000 0,09313952 0,10205855 ! mesoderm development GO:0007498 76 55 0,000 0,09313952 0,10200996 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,09313952 0,1019614 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,09313952 0,1019129 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,09475269 0,10362872 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,09475269 0,10357946 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,09475269 0,10353026 ! carbohydrate transport GO:0008643 74 57 0,000 0,09636308 0,10523983 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,09636308 0,10518989 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,09636308 0,10513999 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,09636308 0,10509013 ! camera-type eye development GO:0043010 88 57 0,000 0,09636308 0,10504033 ! secondary metabolic process GO:0019748 84 57 0,000 0,09636308 0,10499057 ! developmental maturation GO:0021700 75 57 0,000 0,09636308 0,10494086 ! gonad development GO:0008406 79 57 0,000 0,09636308 0,10489119 ! viral reproductive process GO:0022415 87 58 0,000 0,0979707 0,10659064 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,0979707 0,10654024 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,0979707 0,10648989 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,0979707 0,10643959 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,09957555 0,10813209 ! activation of MAPK activity GO:0000187 84 59 0,000 0,09957555 0,10808106 ! lung development GO:0030324 94 59 0,000 0,09957555 0,10803008 ! actin filament organization GO:0007015 95 59 0,000 0,09957555 0,10797915 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,09957555 0,10792826 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,09957555 0,10787742 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,10117764 0,10956147 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,10117764 0,10950991 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,10117764 0,1094584 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,10117764 0,10940694 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,10117764 0,10935553 ! regulation of heart contraction GO:0008016 91 60 0,000 0,10117764 0,10930416 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,10117764 0,10925285 ! fertilization GO:0009566 68 60 0,000 0,10117764 0,10920158 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,10117764 0,10915036 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,10277697 0,11082373 ! meiosis GO:0007126 96 61 0,000 0,10277697 0,1107718 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,10277697 0,11071992 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,10277697 0,11066808 ! urogenital system development GO:0001655 101 61 0,000 0,10277697 0,11061629 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,10277697 0,11056456 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,10277697 0,11051287 ! extracellular matrix organization GO:0030198 103 61 0,000 0,10277697 0,11046122 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,10277697 0,11040963 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,10437354 0,11207243 ! neurotransmitter transport GO:0006836 81 62 0,000 0,10437354 0,11202013 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,10437354 0,11196788 ! respiratory tube development GO:0030323 99 62 0,000 0,10437354 0,11191568 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,10437354 0,11186353 ! meiotic cell cycle GO:0051321 97 62 0,000 0,10437354 0,11181143 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,10596736 0,11346599 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,10596736 0,11341319 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,10596736 0,11336044 ! viral reproduction GO:0016032 92 63 0,000 0,10596736 0,11330773 ! regulation of lipase activity GO:0060191 109 63 0,000 0,10596736 0,11325508 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,10755844 0,11490219 ! appendage morphogenesis GO:0035107 93 64 0,000 0,10755844 0,11484885 GO:0035108|limb morphogenesis, ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,10755844 0,11479555 ! hexose catabolic process GO:0019320 82 64 0,000 0,10755844 0,11474231 ! respiratory system development GO:0060541 100 64 0,000 0,10755844 0,11468911 ! adaptive immune response GO:0002250 94 64 0,000 0,10755844 0,11463597 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,10914678 0,11627494 ! appendage development GO:0048736 94 65 0,000 0,10914678 0,11622111 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,10914678 0,11616733 ! defense response to bacterium GO:0042742 73 65 0,000 0,10914678 0,1161136 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,10914678 0,11605992 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,10914678 0,11600628 ! activation of immune response GO:0002253 83 65 0,000 0,10914678 0,1159527 ! protein oligomerization GO:0051259 100 65 0,000 0,10914678 0,11589917 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,11073239 0,1175286 ! antigen processing and presentation GO:0019882 96 66 0,000 0,11073239 0,11747439 ! axon guidance GO:0007411 99 66 0,000 0,11073239 0,11742023 ! regulation of immune effector process GO:0002697 101 66 0,000 0,11073239 0,11736612 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,11231526 0,11898899 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,11231526 0,1189342 ! acute inflammatory response GO:0002526 92 68 0,000 0,1138954 0,12055197 ! learning or memory GO:0007611 123 68 0,000 0,1138954 0,12049652 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,1138954 0,12044112 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,1138954 0,12038577 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,1138954 0,12033047 ! rhythmic process GO:0048511 105 68 0,000 0,1138954 0,12027522 ! inorganic anion transport GO:0015698 93 68 0,000 0,1138954 0,12022002 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,11547283 0,12182913 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,11547283 0,12177327 ! response to drug GO:0042493 108 69 0,000 0,11547283 0,12171746 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,11704753 0,12332081 ! humoral immune response GO:0006959 86 70 0,000 0,11704753 0,12326434 ! eye development GO:0001654 111 70 0,000 0,11704753 0,12320793 ! amine transport GO:0015837 101 70 0,000 0,11704753 0,12315156 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,11704753 0,12309525 ! regulation of catabolic process GO:0009894 106 70 0,000 0,11704753 0,12303899 ! muscle cell differentiation GO:0042692 104 71 0,000 0,11861952 0,12463449 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,11861952 0,12457758 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,11861952 0,12452072 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,11861952 0,12446392 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,11861952 0,12440716 ! response to hypoxia GO:0001666 132 72 0,000 0,12018881 0,12599556 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,12018881 0,12593816 ! negative regulation of transport GO:0051051 116 73 0,000 0,12175539 0,12752158 ! regulation of blood pressure GO:0008217 107 73 0,000 0,12175539 0,12746354 ! tube morphogenesis GO:0035239 118 73 0,000 0,12175539 0,12740554 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,12175539 0,12734761 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,12175539 0,12728972 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,12331927 0,12886611 ! response to oxygen levels GO:0070482 137 74 0,000 0,12331927 0,12880759 ! digestion GO:0007586 97 74 0,000 0,12331927 0,12874912 ! protein import into nucleus GO:0006606 118 74 0,000 0,12331927 0,1286907 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,12331927 0,12863234 ! blood coagulation GO:0007596 116 75 0,000 0,12488045 0,13020174 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 0,000 0,12488045 0,13014274 ! nuclear import GO:0051170 121 75 0,000 0,12488045 0,1300838 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,12488045 0,13002491 ! amine biosynthetic process GO:0009309 97 76 0,000 0,12643894 0,13158804 ! tRNA metabolic process GO:0006399 95 76 0,000 0,12643894 0,13152853 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,12643894 0,13146906 ! regulation of protein transport GO:0051223 114 76 0,000 0,12643894 0,13140966 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,12799475 0,13296654 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,12799475 0,13290651 ! gland development GO:0048732 148 77 0,000 0,12799475 0,13284654 ! sex differentiation GO:0007548 105 77 0,000 0,12799475 0,13278662 ! protein ubiquitination GO:0016567 125 77 0,000 0,12799475 0,13272675 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,12799475 0,13266694 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,12799475 0,13260718 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,12799475 0,13254747 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,12954788 0,13409546 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,12954788 0,13403514 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,13109833 0,13557831 ! cellular respiration GO:0045333 107 79 0,000 0,13109833 0,13551737 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,13109833 0,13545649 ! T cell activation GO:0042110 134 79 0,000 0,13109833 0,13539567 ! regulation of lyase activity GO:0051339 133 79 0,000 0,13109833 0,1353349 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,13109833 0,13527418 ! alcohol catabolic process GO:0046164 104 80 0,000 0,1326461 0,13680988 ! protein localization in nucleus GO:0034504 133 80 0,000 0,1326461 0,13674856 ! forebrain development GO:0030900 131 80 0,000 0,1326461 0,13668729 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,13419121 0,13821755 ! hemostasis GO:0007599 125 81 0,000 0,13419121 0,13815568 ! mRNA transport GO:0051028 121 81 0,000 0,13419121 0,13809386 ! regulation of neurological system process GO:0031644 122 81 0,000 0,13419121 0,1380321 ! vitamin metabolic process GO:0006766 103 81 0,000 0,13419121 0,1379704 ! ossification GO:0001503 134 82 0,000 0,13573366 0,13949393 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,13573366 0,13943163 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,13727344 0,14095041 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,13727344 0,14088751 ! regulation of defense response GO:0031347 117 84 0,000 0,13881057 0,14240157 ! sterol metabolic process GO:0016125 120 84 0,000 0,13881057 0,14233808 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,14034505 0,14384742 ! rRNA metabolic process GO:0016072 107 85 0,000 0,14034505 0,14378335 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,14034505 0,14371933 ! transcription initiation GO:0006352 118 85 0,000 0,14034505 0,14365537 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,14034505 0,14359147 ! regulation of protein localization GO:0032880 132 85 0,000 0,14034505 0,14352762 ! regulation of membrane potential GO:0042391 128 85 0,000 0,14034505 0,14346383 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,14034505 0,1434001 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,14187688 0,1449009 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,14340607 0,14639768 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,14340607 0,14633273 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,14340607 0,14626784 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,14340607 0,146203 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,14340607 0,14613822 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,14493263 0,14762845 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,14493263 0,1475631 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,14493263 0,14749781 GO:0016054|organic acid catabolic process, ! protein processing GO:0016485 114 88 0,000 0,14493263 0,14743257 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,14645655 0,14891692 ! reproductive developmental process GO:0003006 127 89 0,000 0,14645655 0,14885111 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,14645655 0,14878536 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,14645655 0,14871968 ! regulation of T cell activation GO:0050863 128 89 0,000 0,14645655 0,14865405 ! leukocyte differentiation GO:0002521 143 90 0,000 0,14797784 0,15013191 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,14797784 0,15006571 ! hormone metabolic process GO:0042445 121 90 0,000 0,14797784 0,14999958 ! ATP metabolic process GO:0046034 137 91 0,000 0,14949651 0,15147224 ! response to virus GO:0009615 122 91 0,000 0,14949651 0,15140554 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,15101256 0,15287363 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,15101256 0,15280638 ! cell fate commitment GO:0045165 141 92 0,000 0,15101256 0,15273918 ! positive regulation of immune response GO:0050778 121 92 0,000 0,15101256 0,15267204 ! DNA recombination GO:0006310 146 92 0,000 0,15101256 0,15260496 ! sulfur metabolic process GO:0006790 118 92 0,000 0,15101256 0,15253794 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,15252599 0,15399903 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,15252599 0,15393146 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,15252599 0,15386394 ! electron transport chain GO:0022900 123 94 0,000 0,15403682 0,15531989 ! response to oxidative stress GO:0006979 141 94 0,000 0,15403682 0,15525183 ! angiogenesis GO:0001525 149 95 0,000 0,15554503 0,15670327 ! carboxylic acid transport GO:0046942 147 95 0,000 0,15554503 0,15663467 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,15705065 0,15808161 ! in utero embryonic development GO:0001701 147 96 0,000 0,15705065 0,15801246 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,15705065 0,15794337 ! protein maturation GO:0051604 129 96 0,000 0,15705065 0,15787434 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,15855366 0,15931561 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,15855366 0,15924604 ! calcium ion transport GO:0006816 167 99 0,000 0,16155192 0,16218656 ! extracellular structure organization GO:0043062 156 99 0,000 0,16155192 0,1621158 ! protein import GO:0017038 156 99 0,000 0,16155192 0,1620451 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,16304716 0,16347362 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,16304716 0,16340239 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,16304716 0,16333122 ! divalent metal ion transport GO:0070838 171 100 0,000 0,16304716 0,16326011 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,16304716 0,16318907 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,16304716 0,16311809 ! protein localization in organelle GO:0033365 161 100 0,000 0,16304716 0,16304716