pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/10907-0-real-Zhou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL4685_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of translational initiation GO:0006446 70 46 2,000 9,222E-06 0,02188438 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 1,158E-05 0,01374004 ! ribonucleoprotein complex assembly GO:0022618 90 54 2,000 1,5E-05 0,01186579 ! DNA fragmentation involved in apoptosis GO:0006309 20 16 1,000 9,215E-05 0,05466615 ! cell structure disassembly during apoptosis GO:0006921 25 20 1,000 1,456E-04 0,06909541 ! apoptotic nuclear changes GO:0030262 31 21 1,000 1,608E-04 0,06360639 ! DNA catabolic process, endonucleolytic GO:0000737 27 22 1,000 1,768E-04 0,05993959 ! spliceosomal snRNP biogenesis GO:0000387 38 27 1,000 2,679E-04 0,07947904 ! response to heat GO:0009408 43 30 1,000 3,315E-04 0,08741455 ! spliceosome assembly GO:0000245 65 36 1,000 4,786E-04 0,11357447 ! nucleus organization GO:0006997 58 37 1,000 5,057E-04 0,109091 ! cellular component disassembly GO:0022411 66 44 1,000 7,156E-04 0,14151029 ! activation of caspase activity GO:0006919 70 46 1,000 7,821E-04 0,14276103 ! response to temperature stimulus GO:0009266 66 49 1,000 8,872E-04 0,15038131 ! positive regulation of caspase activity GO:0043280 77 51 1,000 9,609E-04 0,15200859 GO:0010952|positive regulation of peptidase activity, ! DNA catabolic process GO:0006308 71 56 1,000 1,157E-03 0,17166693 ! regulation of caspase activity GO:0043281 104 68 1,000 1,701E-03 0,23746495 ! regulation of endopeptidase activity GO:0052548 106 70 1,000 1,802E-03 0,23750581 ! cell-matrix adhesion GO:0007160 133 71 1,000 1,853E-03 0,23140347 ! regulation of peptidase activity GO:0052547 113 75 1,000 2,065E-03 0,24496271 ! cell-substrate adhesion GO:0031589 141 76 1,000 2,119E-03 0,23947493 ! response to unfolded protein GO:0006986 113 80 1,000 2,345E-03 0,25291171 ! cellular respiration GO:0045333 119 85 1,000 2,642E-03 0,27257288 ! response to protein stimulus GO:0051789 127 85 1,000 2,642E-03 0,26121568 ! electron transport chain GO:0022900 135 99 1,000 3,563E-03 0,33820508 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 4,518E-03 0,41231891 ! positive regulation of protein ubiquitination GO:0031398 8 5 0,000 4,518E-03 0,39704784 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 4,518E-03 0,38286756 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 5 0,000 4,518E-03 0,36966523 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 4,518E-03 0,35734306 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! negative regulation of tyrosine phosphorylation of Stat3 protein GO:0042518 13 5 0,000 4,518E-03 0,34581586 GO:0042532|negative regulation of tyrosine phosphorylation of STAT protein, ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 4,518E-03 0,33500912 ! regulation of cGMP biosynthetic process GO:0030826 7 5 0,000 4,518E-03 0,32485732 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 4,518E-03 0,3153027 ! positive regulation of actin filament polymerization GO:0030838 8 5 0,000 4,518E-03 0,30629405 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 7 5 0,000 4,518E-03 0,29778588 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 4,518E-03 0,28973761 ! response to oxygen radical GO:0000305 11 5 0,000 4,518E-03 0,28211294 ! negative regulation of bone resorption GO:0045779 11 5 0,000 4,518E-03 0,27487927 ! myoblast cell fate commitment GO:0048625 8 5 0,000 4,518E-03 0,26800729 ! nucleotide-sugar transport GO:0015780 8 5 0,000 4,518E-03 0,26147053 ! positive regulation of lipid biosynthetic process GO:0046889 7 5 0,000 4,518E-03 0,25524504 ! regulation of interferon-beta production GO:0032648 5 5 0,000 4,518E-03 0,24930911 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 6 5 0,000 4,518E-03 0,24364299 GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 6 5 0,000 4,518E-03 0,2382287 ! female meiosis GO:0007143 8 5 0,000 4,518E-03 0,23304982 ! nose development GO:0043584 10 5 0,000 4,518E-03 0,22809131 ! DNA catabolic process, exonucleolytic GO:0000738 7 5 0,000 4,518E-03 0,22333941 ! regulation of cell adhesion mediated by integrin GO:0033628 15 5 0,000 4,518E-03 0,21878146 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 4,518E-03 0,21440583 ! short-chain fatty acid metabolic process GO:0046459 8 5 0,000 4,518E-03 0,2102018 ! tryptophanyl-tRNA aminoacylation GO:0006436 6 5 0,000 4,518E-03 0,20615946 ! cobalt ion transport GO:0006824 9 5 0,000 4,518E-03 0,20226966 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 4,518E-03 0,19852392 ! SMAD protein complex assembly GO:0007183 10 5 0,000 4,518E-03 0,19491439 ! phospholipid dephosphorylation GO:0046839 7 5 0,000 4,518E-03 0,19143378 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 4,518E-03 0,18807529 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 4,518E-03 0,18483262 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 4,518E-03 0,18169986 ! adaptation of signaling pathway GO:0022401 9 5 0,000 4,518E-03 0,17867153 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! cardiac muscle cell proliferation GO:0060038 7 5 0,000 4,518E-03 0,17574249 GO:0014855|striated muscle cell proliferation, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 4,518E-03 0,17290793 ! negative regulation of gene-specific transcription GO:0032582 10 5 0,000 4,518E-03 0,17016336 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 4,518E-03 0,16750456 ! negative regulation of histone modification GO:0031057 7 5 0,000 4,518E-03 0,16492756 ! malate metabolic process GO:0006108 8 5 0,000 4,518E-03 0,16242866 ! positive regulation of histone modification GO:0031058 6 5 0,000 4,518E-03 0,16000435 ! transcription from mitochondrial promoter GO:0006390 8 5 0,000 4,518E-03 0,15765135 ! clathrin coat assembly GO:0048268 11 5 0,000 4,518E-03 0,15536655 ! Notch receptor processing GO:0007220 8 5 0,000 4,518E-03 0,15314702 ! phototransduction, visible light GO:0007603 7 5 0,000 4,518E-03 0,15099002 ! regulation of dopamine uptake GO:0051584 9 5 0,000 4,518E-03 0,14889294 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 4,518E-03 0,14685331 ! mating behavior GO:0007617 6 5 0,000 4,518E-03 0,14486881 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 4,518E-03 0,14293722 ! copulation GO:0007620 8 5 0,000 4,518E-03 0,14105647 ! protein maturation by protein folding GO:0022417 13 5 0,000 4,518E-03 0,13922457 ! embryonic hemopoiesis GO:0035162 13 5 0,000 4,518E-03 0,13743964 ! regulation of potassium ion transport GO:0043266 9 5 0,000 4,518E-03 0,1356999 ! apoptotic cell clearance GO:0043277 14 5 0,000 4,518E-03 0,13400365 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 9 5 0,000 4,518E-03 0,13234928 ! lipoprotein particle clearance GO:0034381 9 5 0,000 4,518E-03 0,13073526 ! fructose 1,6-bisphosphate metabolic process GO:0030388 8 5 0,000 4,518E-03 0,12916014 ! regulation of smooth muscle cell apoptosis GO:0034391 8 5 0,000 4,518E-03 0,12762252 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 4,518E-03 0,12612108 GO:0046329|negative regulation of JNK cascade, ! oocyte maturation GO:0001556 6 5 0,000 4,518E-03 0,12465455 ! response to axon injury GO:0048678 8 5 0,000 4,518E-03 0,12322174 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 4,518E-03 0,1218215 ! response to protozoan GO:0001562 10 5 0,000 4,518E-03 0,12045272 ! negative regulation of heart contraction GO:0045822 12 5 0,000 4,518E-03 0,11911435 ! lymph vessel development GO:0001945 8 5 0,000 4,518E-03 0,1178054 ! regulation of activin receptor signaling pathway GO:0032925 11 5 0,000 4,518E-03 0,11652491 ! endochondral ossification GO:0001958 13 5 0,000 4,518E-03 0,11527195 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 4,518E-03 0,11404566 ! single strand break repair GO:0000012 5 5 0,000 4,518E-03 0,11284518 ! parathyroid gland development GO:0060017 8 5 0,000 4,518E-03 0,11166971 ! anagen GO:0042640 7 5 0,000 4,518E-03 0,11051847 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 4,518E-03 0,10939073 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 4,518E-03 0,10828577 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 4,518E-03 0,10720292 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 8 5 0,000 4,518E-03 0,1061415 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 8 5 0,000 4,518E-03 0,1051009 ! smooth muscle tissue development GO:0048745 14 5 0,000 4,518E-03 0,1040805 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 4,518E-03 0,10307973 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 4,518E-03 0,10209802 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 4,518E-03 0,10113483 ! cardiac muscle fiber development GO:0048739 8 5 0,000 4,518E-03 0,10018964 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 4,518E-03 0,09926196 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 8 5 0,000 4,518E-03 0,0983513 ! neutrophil mediated immunity GO:0002446 6 5 0,000 4,518E-03 0,0974572 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 4,518E-03 0,0965792 ! regulation of oligodendrocyte differentiation GO:0048713 15 5 0,000 4,518E-03 0,09571689 GO:0048715|negative regulation of oligodendrocyte differentiation, ! mitochondrion localization, microtubule-mediated GO:0034643 9 5 0,000 4,518E-03 0,09486984 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! negative regulation of RNA splicing GO:0033119 6 5 0,000 4,518E-03 0,09403765 ! ionotropic glutamate receptor signaling pathway GO:0035235 10 5 0,000 4,518E-03 0,09321993 ! positive regulation of isotype switching to IgG isotypes GO:0048304 8 5 0,000 4,518E-03 0,09241631 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 4,518E-03 0,09162642 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 9 5 0,000 4,518E-03 0,09084993 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 4,518E-03 0,09008649 ! tyrosine catabolic process GO:0006572 7 5 0,000 4,518E-03 0,08933576 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 4,518E-03 0,08859745 ! proline biosynthetic process GO:0006561 6 5 0,000 4,518E-03 0,08787124 ! L-serine biosynthetic process GO:0006564 6 5 0,000 4,518E-03 0,08715684 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 4,518E-03 0,08645397 ! polyol catabolic process GO:0046174 7 5 0,000 4,518E-03 0,08576233 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 4,518E-03 0,08508168 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 4,518E-03 0,08441175 ! sister chromatid cohesion GO:0007062 10 5 0,000 4,518E-03 0,08375228 ! response to ATP GO:0033198 6 5 0,000 4,518E-03 0,08310304 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 9 5 0,000 4,518E-03 0,08246378 ! positive regulation of stress fiber formation GO:0051496 15 5 0,000 4,518E-03 0,08183429 ! neutrophil activation GO:0042119 6 5 0,000 4,518E-03 0,08121433 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 4,518E-03 0,0806037 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 4,518E-03 0,08000218 ! response to food GO:0032094 5 5 0,000 4,518E-03 0,07940957 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 4,518E-03 0,07882567 GO:0043088|regulation of Cdc42 GTPase activity, ! positive regulation of transporter activity GO:0032411 5 5 0,000 4,518E-03 0,0782503 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 8 5 0,000 4,518E-03 0,07768327 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 4,518E-03 0,0771244 ! paraxial mesoderm development GO:0048339 9 5 0,000 4,518E-03 0,07657351 ! forebrain neuron development GO:0021884 7 5 0,000 4,518E-03 0,07603044 ! melanosome organization GO:0032438 7 5 0,000 4,518E-03 0,07549501 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 4,518E-03 0,07496707 ! virus-infected cell apoptosis GO:0006926 8 5 0,000 4,518E-03 0,07444647 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 4,518E-03 0,07393305 ! positive regulation of neuroblast proliferation GO:0002052 9 5 0,000 4,518E-03 0,07342666 ! mesodermal cell fate determination GO:0007500 7 5 0,000 4,518E-03 0,07292715 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 4,518E-03 0,0724344 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 8 5 0,000 4,518E-03 0,07194827 ! nucleoside salvage GO:0043174 7 5 0,000 4,518E-03 0,07146861 GO:0006166|purine ribonucleoside salvage, ! lipid glycosylation GO:0030259 6 5 0,000 4,518E-03 0,07099531 ! attachment of GPI anchor to protein GO:0016255 10 5 0,000 4,518E-03 0,07052823 ! negative regulation of platelet activation GO:0010544 8 5 0,000 4,518E-03 0,07006727 GO:0010543|regulation of platelet activation, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 4,518E-03 0,06961228 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 4,518E-03 0,06916317 ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 4,518E-03 0,06871982 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of fatty acid metabolic process GO:0045923 6 5 0,000 4,518E-03 0,06828211 ! early endosome to late endosome transport GO:0045022 11 5 0,000 4,518E-03 0,06784995 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 6 5 0,000 4,518E-03 0,06742322 ! depyrimidination GO:0045008 8 5 0,000 4,518E-03 0,06700182 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 4,518E-03 0,06658566 ! 5S class rRNA transcription GO:0042791 8 5 0,000 4,518E-03 0,06617464 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 5 0,000 4,518E-03 0,06576866 ! neuronal ion channel clustering GO:0045161 8 5 0,000 4,518E-03 0,06536763 ! sodium ion homeostasis GO:0055078 6 5 0,000 4,518E-03 0,06497146 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 4,518E-03 0,06458007 ! monocyte differentiation GO:0030224 7 5 0,000 4,518E-03 0,06419336 ! negative regulation of peptide secretion GO:0002792 8 5 0,000 4,518E-03 0,06381126 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 6 5 0,000 4,518E-03 0,06343368 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 4,518E-03 0,06306054 ! response to UV-C GO:0010225 7 5 0,000 4,518E-03 0,06269176 ! protein targeting to vacuole GO:0006623 6 5 0,000 4,518E-03 0,06232728 ! activated T cell proliferation GO:0050798 7 5 0,000 4,518E-03 0,061967 ! negative regulation of alpha-beta T cell activation GO:0046636 7 5 0,000 4,518E-03 0,06161087 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! regulation of alpha-beta T cell proliferation GO:0046640 13 5 0,000 4,518E-03 0,06125881 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 4,518E-03 0,06091075 ! regulation of integrin biosynthetic process GO:0045113 9 5 0,000 4,518E-03 0,06056662 ! regulation of killing of cells of another organism GO:0051709 6 5 0,000 4,518E-03 0,06022636 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 4,518E-03 0,0598899 ! lymphoid progenitor cell differentiation GO:0002320 12 5 0,000 4,518E-03 0,05955718 ! positive regulation of T cell cytokine production GO:0002726 9 5 0,000 4,518E-03 0,05922813 GO:0032743|positive regulation of interleukin-2 production, ! L-ascorbic acid metabolic process GO:0019852 7 5 0,000 4,518E-03 0,0589027 ! base-excision repair, DNA ligation GO:0006288 5 5 0,000 4,518E-03 0,05858083 ! response to cadmium ion GO:0046686 8 5 0,000 4,518E-03 0,05826245 ! melanosome transport GO:0032402 8 5 0,000 4,518E-03 0,05794752 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 4,518E-03 0,05763598 ! regulation of acetylcholine secretion GO:0014056 10 5 0,000 4,518E-03 0,05732776 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 4,518E-03 0,05702283 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 4,518E-03 0,05672112 ! positive T cell selection GO:0043368 10 5 0,000 4,518E-03 0,05642259 ! purine deoxyribonucleotide catabolic process GO:0009155 6 5 0,000 4,518E-03 0,05612718 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 4,518E-03 0,05583485 ! regulation of interleukin-1 production GO:0032652 8 5 0,000 4,518E-03 0,05554555 ! ribosomal subunit assembly GO:0042257 5 5 0,000 4,518E-03 0,05525924 ! base conversion or substitution editing GO:0016553 6 5 0,000 4,518E-03 0,05497585 ! regulation of chondrocyte differentiation GO:0032330 9 5 0,000 4,518E-03 0,05469537 ! negative regulation of monooxygenase activity GO:0032769 10 5 0,000 4,518E-03 0,05441772 ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 4,518E-03 0,05414289 ! positive regulation of interleukin-12 production GO:0032735 5 5 0,000 4,518E-03 0,05387081 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 4,518E-03 0,05360146 ! histone demethylation GO:0016577 10 5 0,000 4,518E-03 0,05333478 ! mitotic recombination GO:0006312 10 5 0,000 4,518E-03 0,05307075 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 5 0,000 4,518E-03 0,05280932 ! regulation of sterol transport GO:0032371 7 5 0,000 4,518E-03 0,05255045 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 4,518E-03 0,05229411 ! sympathetic nervous system development GO:0048485 13 5 0,000 4,518E-03 0,05204025 ! enteric nervous system development GO:0048484 9 5 0,000 4,518E-03 0,05178885 ! oxygen homeostasis GO:0032364 8 5 0,000 4,518E-03 0,05153986 ! establishment of planar polarity GO:0001736 7 5 0,000 4,518E-03 0,05129326 ! lymphocyte costimulation GO:0031294 12 5 0,000 4,518E-03 0,05104901 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 6 5 0,000 4,518E-03 0,05080707 ! transcription termination GO:0006353 8 5 0,000 4,518E-03 0,05056741 ! plasminogen activation GO:0031639 5 5 0,000 4,518E-03 0,05033001 ! B cell homeostasis GO:0001782 12 5 0,000 4,518E-03 0,05009482 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 4,518E-03 0,04986182 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 4,518E-03 0,04963098 ! regulation of hair follicle development GO:0051797 9 5 0,000 4,518E-03 0,04940227 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 4,518E-03 0,04917565 ! apical protein localization GO:0045176 8 5 0,000 4,518E-03 0,0489511 ! definitive hemopoiesis GO:0060216 5 5 0,000 4,518E-03 0,0487286 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 4,518E-03 0,04850811 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 4,518E-03 0,0482896 ! glucocorticoid biosynthetic process GO:0006704 6 5 0,000 4,518E-03 0,04807306 ! regulation of keratinocyte differentiation GO:0045616 7 5 0,000 4,518E-03 0,04785845 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 4,518E-03 0,04764574 ! regulation of centrosome duplication GO:0010824 6 5 0,000 4,518E-03 0,04743492 ! disaccharide metabolic process GO:0005984 9 5 0,000 4,518E-03 0,04722595 ! galactolipid metabolic process GO:0019374 8 5 0,000 4,518E-03 0,04701882 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 4,518E-03 0,0468135 GO:0033015|tetrapyrrole catabolic process, ! positive regulation of T cell mediated cytotoxicity GO:0001916 11 5 0,000 4,518E-03 0,04660996 ! determination of adult lifespan GO:0008340 8 5 0,000 4,518E-03 0,04640819 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 4,518E-03 0,04620815 ! ectodermal gut morphogenesis GO:0048567 6 5 0,000 4,518E-03 0,04600984 GO:0007439|ectodermal gut development, ! somatic stem cell maintenance GO:0035019 14 5 0,000 4,518E-03 0,04581321 ! T cell activation during immune response GO:0002286 9 5 0,000 4,518E-03 0,04561826 ! negative regulation of fibrinolysis GO:0051918 9 5 0,000 4,518E-03 0,04542496 ! negative regulation of lipase activity GO:0060192 7 5 0,000 4,518E-03 0,0452333 ! establishment of apical/basal cell polarity GO:0035089 7 5 0,000 4,518E-03 0,04504324 ! neural plate development GO:0001840 7 5 0,000 4,518E-03 0,04485478 ! regulation of sensory perception GO:0051931 6 5 0,000 4,518E-03 0,04466788 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 10 5 0,000 4,518E-03 0,04448254 ! regulation of histone acetylation GO:0035065 7 5 0,000 4,518E-03 0,04429873 ! sensory cilium assembly GO:0035058 6 5 0,000 4,518E-03 0,04411643 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 14 5 0,000 4,518E-03 0,04393562 ! diacylglycerol metabolic process GO:0046339 8 5 0,000 4,518E-03 0,04375629 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 4,518E-03 0,04357842 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 11 5 0,000 4,518E-03 0,04340199 ! negative regulation of smooth muscle contraction GO:0045986 10 5 0,000 4,518E-03 0,04322698 ! receptor biosynthetic process GO:0032800 6 5 0,000 4,518E-03 0,04305338 ! penetration of zona pellucida GO:0007341 9 5 0,000 4,518E-03 0,04288117 ! drug metabolic process GO:0017144 5 5 0,000 4,518E-03 0,04271033 ! protein amino acid prenylation GO:0018346 9 5 0,000 4,518E-03 0,04254084 ! organ regeneration GO:0031100 7 5 0,000 4,518E-03 0,04237269 ! carnitine metabolic process GO:0009437 5 5 0,000 4,518E-03 0,04220587 GO:0006577|betaine metabolic process, ! tRNA transcription GO:0009304 11 6 0,000 5,419E-03 0,05042688 ! negative regulation of S phase of mitotic cell cycle GO:0045749 13 6 0,000 5,419E-03 0,0502299 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 5,419E-03 0,05003445 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 8 6 0,000 5,419E-03 0,04984052 ! regulation of helicase activity GO:0051095 11 6 0,000 5,419E-03 0,04964809 ! regulation of cGMP metabolic process GO:0030823 8 6 0,000 5,419E-03 0,04945713 ! sleep GO:0030431 13 6 0,000 5,419E-03 0,04926764 ! positive regulation of axon extension GO:0045773 10 6 0,000 5,419E-03 0,0490796 ! negative regulation of small GTPase mediated signal transduction GO:0051058 11 6 0,000 5,419E-03 0,04889298 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 5,419E-03 0,04870778 ! forebrain regionalization GO:0021871 7 6 0,000 5,419E-03 0,04852398 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 5,419E-03 0,04834156 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 5,419E-03 0,0481605 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 5,419E-03 0,0479808 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 5,419E-03 0,04780243 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 18 6 0,000 5,419E-03 0,04762539 ! regulation of protein export from nucleus GO:0046825 8 6 0,000 5,419E-03 0,04744965 ! neuron adhesion GO:0007158 9 6 0,000 5,419E-03 0,0472752 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 5,419E-03 0,04710203 ! signal peptide processing GO:0006465 8 6 0,000 5,419E-03 0,04693012 ! embryonic camera-type eye development GO:0031076 11 6 0,000 5,419E-03 0,04675947 GO:0048596|embryonic camera-type eye morphogenesis, ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 5,419E-03 0,04659005 ! glucocorticoid receptor signaling pathway GO:0042921 11 6 0,000 5,419E-03 0,04642186 GO:0031958|corticosteroid receptor signaling pathway, ! citrate metabolic process GO:0006101 10 6 0,000 5,419E-03 0,04625487 ! fibril organization GO:0043206 13 6 0,000 5,419E-03 0,04608908 ! regulation of mitochondrial membrane permeability GO:0046902 12 6 0,000 5,419E-03 0,04592448 ! neurofilament cytoskeleton organization GO:0060052 10 6 0,000 5,419E-03 0,04576105 ! posttranscriptional gene silencing by RNA GO:0035194 14 6 0,000 5,419E-03 0,04559877 GO:0016441|posttranscriptional gene silencing, ! behavioral response to pain GO:0048266 10 6 0,000 5,419E-03 0,04543765 ! protein refolding GO:0042026 13 6 0,000 5,419E-03 0,04527766 ! metabotropic glutamate receptor signaling pathway GO:0007216 8 6 0,000 5,419E-03 0,04511879 ! rhythmic behavior GO:0007622 14 6 0,000 5,419E-03 0,04496103 ! glial cell fate commitment GO:0021781 17 6 0,000 5,419E-03 0,04480437 ! erythrocyte maturation GO:0043249 7 6 0,000 5,419E-03 0,0446488 ! sensory perception of temperature stimulus GO:0050951 12 6 0,000 5,419E-03 0,0444943 ! protein amino acid dealkylation GO:0008214 12 6 0,000 5,419E-03 0,04434088 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 5,419E-03 0,0441885 ! regulation of odontogenesis GO:0042481 8 6 0,000 5,419E-03 0,04403717 ! mechanosensory behavior GO:0007638 8 6 0,000 5,419E-03 0,04388687 ! ovulation from ovarian follicle GO:0001542 7 6 0,000 5,419E-03 0,0437376 ! negative regulation of endocytosis GO:0045806 8 6 0,000 5,419E-03 0,04358934 ! response to interferon-gamma GO:0034341 12 6 0,000 5,419E-03 0,04344207 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 5,419E-03 0,0432958 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 9 6 0,000 5,419E-03 0,04315052 ! negative regulation of viral genome replication GO:0045071 8 6 0,000 5,419E-03 0,0430062 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 6 6 0,000 5,419E-03 0,04286285 ! spinal cord dorsal/ventral patterning GO:0021513 8 6 0,000 5,419E-03 0,04272045 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 17 6 0,000 5,419E-03 0,04257899 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 11 6 0,000 5,419E-03 0,04243846 ! cGMP-mediated signaling GO:0019934 11 6 0,000 5,419E-03 0,04229886 ! activation of MAPKKK activity GO:0000185 11 6 0,000 5,419E-03 0,04216018 ! inositol phosphate-mediated signaling GO:0048016 10 6 0,000 5,419E-03 0,0420224 ! protein lipoylation GO:0009249 10 6 0,000 5,419E-03 0,04188552 ! pigment granule organization GO:0048753 11 6 0,000 5,419E-03 0,04174953 ! drug transport GO:0015893 6 6 0,000 5,419E-03 0,04161441 ! transepithelial chloride transport GO:0030321 10 6 0,000 5,419E-03 0,04148017 GO:0070633|transepithelial transport, ! cysteine metabolic process GO:0006534 8 6 0,000 5,419E-03 0,0413468 ! negative regulation of survival gene product expression GO:0008634 9 6 0,000 5,419E-03 0,04121428 ! regulation of defense response to virus by host GO:0050691 7 6 0,000 5,419E-03 0,0410826 ! glutamate catabolic process GO:0006538 11 6 0,000 5,419E-03 0,04095176 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 5,419E-03 0,04082176 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 5,419E-03 0,04069258 ! adenohypophysis development GO:0021984 10 6 0,000 5,419E-03 0,04056421 ! response to pH GO:0009268 10 6 0,000 5,419E-03 0,04043665 ! hyperosmotic response GO:0006972 9 6 0,000 5,419E-03 0,04030989 ! microtubule nucleation GO:0007020 10 6 0,000 5,419E-03 0,04018392 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 6 0,000 5,419E-03 0,04005874 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 6 0,000 5,419E-03 0,03993433 ! melanin biosynthetic process from tyrosine GO:0006583 9 6 0,000 5,419E-03 0,03981069 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 5,419E-03 0,03968782 ! vascular smooth muscle contraction GO:0014829 11 6 0,000 5,419E-03 0,0395657 ! regulation of retinoic acid receptor signaling pathway GO:0048385 13 6 0,000 5,419E-03 0,03944434 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 5,419E-03 0,03932371 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 5,419E-03 0,03920382 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 5,419E-03 0,03908466 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 5,419E-03 0,03896622 ! purine salvage GO:0043101 9 6 0,000 5,419E-03 0,0388485 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 5,419E-03 0,03873149 ! peptidyl-threonine phosphorylation GO:0018107 16 6 0,000 5,419E-03 0,03861518 ! nucleoside transport GO:0015858 7 6 0,000 5,419E-03 0,03849956 ! organic alcohol transport GO:0015850 9 6 0,000 5,419E-03 0,03838464 ! T cell mediated immunity GO:0002456 12 6 0,000 5,419E-03 0,0382704 ! folic acid transport GO:0015884 11 6 0,000 5,419E-03 0,03815684 ! male sex determination GO:0030238 11 6 0,000 5,419E-03 0,03804395 ! carnitine transport GO:0015879 8 6 0,000 5,419E-03 0,03793172 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 5,419E-03 0,03782016 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 5,419E-03 0,03770925 ! negative regulation of DNA recombination GO:0045910 10 6 0,000 5,419E-03 0,03759899 ! positive regulation of exocytosis GO:0045921 9 6 0,000 5,419E-03 0,03748937 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 5,419E-03 0,03738039 ! parturition GO:0007567 13 6 0,000 5,419E-03 0,03727204 ! determination of anterior/posterior axis, embryo GO:0008595 10 6 0,000 5,419E-03 0,03716432 GO:0007351|tripartite regional subdivision, ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 5,419E-03 0,03705722 ! lipopolysaccharide biosynthetic process GO:0009103 6 6 0,000 5,419E-03 0,03695073 ! regulation of centrosome cycle GO:0046605 8 6 0,000 5,419E-03 0,03684485 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 5,419E-03 0,03673958 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 5,419E-03 0,03663491 ! regulation of cholesterol biosynthetic process GO:0045540 8 6 0,000 5,419E-03 0,03653084 ! homeostasis of number of cells within a tissue GO:0048873 10 6 0,000 5,419E-03 0,03642735 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 5,419E-03 0,03632445 ! negative regulation of gliogenesis GO:0014014 17 6 0,000 5,419E-03 0,03622212 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 10 6 0,000 5,419E-03 0,03612038 ! neural nucleus development GO:0048857 12 6 0,000 5,419E-03 0,0360192 ! forebrain morphogenesis GO:0048853 14 6 0,000 5,419E-03 0,03591859 ! hyaluronan metabolic process GO:0030212 7 6 0,000 5,419E-03 0,03581853 ! purine base biosynthetic process GO:0009113 14 6 0,000 5,419E-03 0,03571904 ! interaction with symbiont GO:0051702 9 6 0,000 5,419E-03 0,03562009 ! regulation of dendrite development GO:0050773 13 6 0,000 5,419E-03 0,0355217 ! anterograde axon cargo transport GO:0008089 9 6 0,000 5,419E-03 0,03542384 ! positive regulation of organ growth GO:0046622 7 6 0,000 5,419E-03 0,03532652 ! eating behavior GO:0042755 6 6 0,000 5,419E-03 0,03522974 ! regulation of T cell cytokine production GO:0002724 11 6 0,000 5,419E-03 0,03513348 ! transcription-coupled nucleotide-excision repair GO:0006283 7 6 0,000 5,419E-03 0,03503775 ! response to copper ion GO:0046688 9 6 0,000 5,419E-03 0,03494254 ! negative regulation of lymphocyte mediated immunity GO:0002707 13 6 0,000 5,419E-03 0,03484784 GO:0002704|negative regulation of leukocyte mediated immunity, ! response to exogenous dsRNA GO:0043330 8 6 0,000 5,419E-03 0,03475366 ! establishment of melanosome localization GO:0032401 9 6 0,000 5,419E-03 0,03465998 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 5,419E-03 0,03456681 ! negative regulation of protein kinase B signaling cascade GO:0051898 12 6 0,000 5,419E-03 0,03447414 ! positive regulation of B cell differentiation GO:0045579 10 6 0,000 5,419E-03 0,03438196 ! regulation of dopamine secretion GO:0014059 14 6 0,000 5,419E-03 0,03429028 ! nucleoside catabolic process GO:0009164 7 6 0,000 5,419E-03 0,03419908 ! hair follicle maturation GO:0048820 8 6 0,000 5,419E-03 0,03410837 ! cranial nerve morphogenesis GO:0021602 7 6 0,000 5,419E-03 0,03401813 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 5,419E-03 0,03392837 ! positive regulation of interleukin-5 production GO:0032754 9 6 0,000 5,419E-03 0,03383909 GO:0032736|positive regulation of interleukin-13 production, ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 5,419E-03 0,03375027 ! rhombomere development GO:0021546 6 6 0,000 5,419E-03 0,03366192 ! positive regulation of Rho GTPase activity GO:0032321 12 6 0,000 5,419E-03 0,03357403 ! G2 phase GO:0051319 15 6 0,000 5,419E-03 0,0334866 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 10 6 0,000 5,419E-03 0,03339962 GO:0050000|chromosome localization, ! regulation of mast cell activation GO:0033003 7 6 0,000 5,419E-03 0,03331309 ! muscle cell proliferation GO:0033002 9 6 0,000 5,419E-03 0,03322701 ! membrane to membrane docking GO:0022614 12 6 0,000 5,419E-03 0,03314138 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 10 6 0,000 5,419E-03 0,03305618 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 12 6 0,000 5,419E-03 0,03297142 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 6 0,000 5,419E-03 0,03288709 ! receptor internalization GO:0031623 9 6 0,000 5,419E-03 0,0328032 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 5,419E-03 0,03271973 GO:0031272|regulation of pseudopodium assembly, ! regulation of respiratory burst GO:0060263 9 6 0,000 5,419E-03 0,03263669 ! coenzyme A metabolic process GO:0015936 9 6 0,000 5,419E-03 0,03255406 ! myeloid dendritic cell activation GO:0001773 11 6 0,000 5,419E-03 0,03247185 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 12 6 0,000 5,419E-03 0,03239006 ! peptidyl-histidine modification GO:0018202 10 6 0,000 5,419E-03 0,03230868 ! axonal fasciculation GO:0007413 10 6 0,000 5,419E-03 0,0322277 ! regulation of muscle cell apoptosis GO:0010660 9 6 0,000 5,419E-03 0,03214714 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 5,419E-03 0,03206697 GO:0015991|ATP hydrolysis coupled proton transport, ! midbrain development GO:0030901 7 6 0,000 5,419E-03 0,0319872 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 5,419E-03 0,03190783 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 5,419E-03 0,03182885 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 7 6 0,000 5,419E-03 0,03175026 ! progesterone metabolic process GO:0042448 8 6 0,000 5,419E-03 0,03167205 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 5,419E-03 0,03159424 ! glycolipid catabolic process GO:0019377 14 6 0,000 5,419E-03 0,0315168 GO:0046479|glycosphingolipid catabolic process, ! nonprotein amino acid metabolic process GO:0019794 10 6 0,000 5,419E-03 0,03143974 ! negative regulation of axon extension GO:0030517 13 6 0,000 5,419E-03 0,03136306 ! removal of superoxide radicals GO:0019430 10 6 0,000 5,419E-03 0,03128675 ! triglyceride catabolic process GO:0019433 8 6 0,000 5,419E-03 0,03121081 ! protein modification by small protein removal GO:0070646 10 6 0,000 5,419E-03 0,03113524 GO:0016579|protein deubiquitination, ! adult feeding behavior GO:0008343 6 6 0,000 5,419E-03 0,03106003 ! regulation of Rac protein signal transduction GO:0035020 9 6 0,000 5,419E-03 0,03098519 ! glial cell migration GO:0008347 11 6 0,000 5,419E-03 0,03091071 ! blastocyst growth GO:0001832 17 6 0,000 5,419E-03 0,03083658 ! pigment granule transport GO:0051904 12 6 0,000 5,419E-03 0,03076281 ! lymphocyte activation during immune response GO:0002285 10 6 0,000 5,419E-03 0,03068939 ! cerebellar cortex formation GO:0021697 9 6 0,000 5,419E-03 0,03061632 ! catecholamine transport GO:0051937 7 6 0,000 5,419E-03 0,0305436 ! hemopoietic progenitor cell differentiation GO:0002244 14 6 0,000 5,419E-03 0,03047122 ! positive regulation of actin filament bundle formation GO:0032233 16 6 0,000 5,419E-03 0,03039918 ! organ or tissue specific immune response GO:0002251 7 6 0,000 5,419E-03 0,03032749 ! positive regulation of smooth muscle contraction GO:0045987 10 6 0,000 5,419E-03 0,03025613 ! spindle assembly GO:0051225 6 6 0,000 5,419E-03 0,0301851 ! ensheathment of axons in the peripheral nervous system GO:0032292 15 6 0,000 5,419E-03 0,03011441 GO:0022011|myelination in the peripheral nervous system, ! protein prenylation GO:0018342 10 6 0,000 5,419E-03 0,03004405 ! negative regulation of synaptic transmission GO:0050805 12 6 0,000 5,419E-03 0,02997402 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 5,419E-03 0,02990431 ! NAD biosynthetic process GO:0009435 9 6 0,000 5,419E-03 0,02983493 ! positive regulation of coagulation GO:0050820 11 6 0,000 5,419E-03 0,02976587 ! cellular anion homeostasis GO:0030002 9 6 0,000 5,419E-03 0,02969712 GO:0055081|anion homeostasis, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 6,319E-03 0,03455205 ! behavioral response to cocaine GO:0048148 13 7 0,000 6,319E-03 0,03447262 ! autophagic vacuole formation GO:0000045 12 7 0,000 6,319E-03 0,03439355 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 6,319E-03 0,03431485 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 10 7 0,000 6,319E-03 0,0342365 ! chaperone mediated protein folding requiring cofactor GO:0051085 9 7 0,000 6,319E-03 0,03415851 ! prostate gland development GO:0030850 11 7 0,000 6,319E-03 0,03408088 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 6,319E-03 0,0340036 ! regulation of hormone biosynthetic process GO:0046885 12 7 0,000 6,319E-03 0,03392667 ! synaptonemal complex assembly GO:0007130 11 7 0,000 6,319E-03 0,03385009 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 10 7 0,000 6,319E-03 0,03377385 ! male meiosis GO:0007140 10 7 0,000 6,319E-03 0,03369795 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 6,319E-03 0,03362239 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! reproductive behavior GO:0019098 12 7 0,000 6,319E-03 0,03354718 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 6,319E-03 0,03347229 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 6,319E-03 0,03339775 ! oligopeptide transport GO:0006857 11 7 0,000 6,319E-03 0,03332353 ! protein amino acid sulfation GO:0006477 9 7 0,000 6,319E-03 0,03324964 GO:0051923|sulfation, ! N-terminal protein amino acid acetylation GO:0006474 9 7 0,000 6,319E-03 0,03317608 ! establishment of tissue polarity GO:0007164 10 7 0,000 6,319E-03 0,03310284 ! receptor guanylyl cyclase signaling pathway GO:0007168 7 7 0,000 6,319E-03 0,03302993 ! RNA methylation GO:0001510 11 7 0,000 6,319E-03 0,03295734 ! negative regulation of cell-cell adhesion GO:0022408 20 7 0,000 6,319E-03 0,03288506 ! positive regulation of cell-cell adhesion GO:0022409 17 7 0,000 6,319E-03 0,0328131 ! pericardium development GO:0060039 9 7 0,000 6,319E-03 0,03274146 ! macrophage chemotaxis GO:0048246 10 7 0,000 6,319E-03 0,03267013 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 6,319E-03 0,0325991 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 6,319E-03 0,03252839 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 6,319E-03 0,03245798 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 6,319E-03 0,03238788 ! cerebral cortex cell migration GO:0021795 11 7 0,000 6,319E-03 0,03231808 ! opsonization GO:0008228 9 7 0,000 6,319E-03 0,03224858 ! tachykinin receptor signaling pathway GO:0007217 12 7 0,000 6,319E-03 0,03217937 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 6,319E-03 0,03211047 ! regulation of dopamine metabolic process GO:0042053 10 7 0,000 6,319E-03 0,03204185 GO:0042069|regulation of catecholamine metabolic process, ! glucocorticoid metabolic process GO:0008211 8 7 0,000 6,319E-03 0,03197353 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 6,319E-03 0,03190551 ! chemosensory behavior GO:0007635 9 7 0,000 6,319E-03 0,03183777 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 6,319E-03 0,03177031 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 6,319E-03 0,03170315 ! leukocyte degranulation GO:0043299 11 7 0,000 6,319E-03 0,03163626 ! positive regulation of glycolysis GO:0045821 13 7 0,000 6,319E-03 0,03156966 ! DNA ligation during DNA repair GO:0051103 10 7 0,000 6,319E-03 0,03150334 ! positive regulation of heart rate GO:0010460 11 7 0,000 6,319E-03 0,03143729 ! protein-cofactor linkage GO:0018065 13 7 0,000 6,319E-03 0,03137152 ! lipopolysaccharide metabolic process GO:0008653 7 7 0,000 6,319E-03 0,03130603 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 6,319E-03 0,03124081 ! spinal cord patterning GO:0021511 9 7 0,000 6,319E-03 0,03117586 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 6,319E-03 0,03111118 ! thymic T cell selection GO:0045061 15 7 0,000 6,319E-03 0,03104677 ! regulation of transcriptional preinitiation complex assembly GO:0045898 11 7 0,000 6,319E-03 0,03098262 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 6,319E-03 0,03091874 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 6,319E-03 0,03085512 ! ovulation GO:0030728 8 7 0,000 6,319E-03 0,03079176 ! regulation of isotype switching to IgG isotypes GO:0048302 11 7 0,000 6,319E-03 0,03072866 ! histidine metabolic process GO:0006547 7 7 0,000 6,319E-03 0,03066582 GO:0009075|histidine family amino acid metabolic process, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 7 0,000 6,319E-03 0,03060324 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 6,319E-03 0,03054091 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! deoxyribonucleotide biosynthetic process GO:0009263 9 7 0,000 6,319E-03 0,03047884 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 6,319E-03 0,03041701 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! ER overload response GO:0006983 8 7 0,000 6,319E-03 0,03035544 ! thyroid hormone generation GO:0006590 11 7 0,000 6,319E-03 0,03029412 ! endosome organization GO:0007032 10 7 0,000 6,319E-03 0,03023304 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 6,319E-03 0,03017221 GO:0021940|positive regulation of granule cell precursor proliferation, ! positive regulation of interleukin-8 biosynthetic process GO:0045416 8 7 0,000 6,319E-03 0,03011162 ! phasic smooth muscle contraction GO:0014821 13 7 0,000 6,319E-03 0,03005128 ! urea metabolic process GO:0019627 9 7 0,000 6,319E-03 0,02999118 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 14 7 0,000 6,319E-03 0,02993131 ! vesicle fusion GO:0006906 15 7 0,000 6,319E-03 0,02987169 ! positive regulation of insulin secretion GO:0032024 9 7 0,000 6,319E-03 0,0298123 ! maintenance of protein location in nucleus GO:0051457 17 7 0,000 6,319E-03 0,02975315 ! intracellular pH reduction GO:0051452 11 7 0,000 6,319E-03 0,02969423 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 10 7 0,000 6,319E-03 0,02963555 GO:0046464|acylglycerol catabolic process, ! asymmetric protein localization GO:0008105 10 7 0,000 6,319E-03 0,0295771 ! organ growth GO:0035265 13 7 0,000 6,319E-03 0,02951887 ! positive regulation of mesenchymal cell proliferation GO:0002053 10 7 0,000 6,319E-03 0,02946088 ! Rac protein signal transduction GO:0016601 7 7 0,000 6,319E-03 0,02940311 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 7 0,000 6,319E-03 0,02934557 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 8 7 0,000 6,319E-03 0,02928826 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! retinol metabolic process GO:0042572 9 7 0,000 6,319E-03 0,02923117 ! positive regulation of mitotic cell cycle GO:0045931 13 7 0,000 6,319E-03 0,0291743 ! rRNA modification GO:0000154 12 7 0,000 6,319E-03 0,02911765 ! negative regulation of translational initiation GO:0045947 9 7 0,000 6,319E-03 0,02906122 ! DNA damage response, signal transduction resulting in transcription GO:0042772 14 7 0,000 6,319E-03 0,02900501 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 20 7 0,000 6,319E-03 0,02894901 ! protein heterooligomerization GO:0051291 10 7 0,000 6,319E-03 0,02889323 ! response to UV-B GO:0010224 11 7 0,000 6,319E-03 0,02883767 ! astrocyte development GO:0014002 15 7 0,000 6,319E-03 0,02878232 ! intermediate filament organization GO:0045109 12 7 0,000 6,319E-03 0,02872718 ! cardiac muscle cell development GO:0055013 9 7 0,000 6,319E-03 0,02867225 ! fibrinolysis GO:0042730 9 7 0,000 6,319E-03 0,02861753 ! peptidyl-arginine modification GO:0018195 9 7 0,000 6,319E-03 0,02856302 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 7 0,000 6,319E-03 0,02850872 ! blastoderm segmentation GO:0007350 11 7 0,000 6,319E-03 0,02845463 ! skeletal muscle contraction GO:0003009 8 7 0,000 6,319E-03 0,02840073 ! B cell lineage commitment GO:0002326 17 7 0,000 6,319E-03 0,02834705 ! DNA topological change GO:0006265 10 7 0,000 6,319E-03 0,02829356 ! regulation of fat cell differentiation GO:0045598 10 7 0,000 6,319E-03 0,02824028 ! melanosome localization GO:0032400 10 7 0,000 6,319E-03 0,0281872 ! enucleate erythrocyte differentiation GO:0043353 10 7 0,000 6,319E-03 0,02813431 ! regulation of interleukin-5 production GO:0032674 10 7 0,000 6,319E-03 0,02808163 ! glycosylceramide metabolic process GO:0006677 10 7 0,000 6,319E-03 0,02802914 ! mast cell activation GO:0045576 10 7 0,000 6,319E-03 0,02797684 ! multicellular organismal aging GO:0010259 11 7 0,000 6,319E-03 0,02792474 ! negative regulation of focal adhesion formation GO:0051895 16 7 0,000 6,319E-03 0,02787284 ! gas homeostasis GO:0033483 12 7 0,000 6,319E-03 0,02782113 ! negative regulation of T cell differentiation GO:0045581 9 7 0,000 6,319E-03 0,02776961 ! phosphatidylinositol biosynthetic process GO:0006661 11 7 0,000 6,319E-03 0,02771828 ! Schwann cell development GO:0014044 16 7 0,000 6,319E-03 0,02766714 ! dendrite morphogenesis GO:0048813 12 7 0,000 6,319E-03 0,02761618 ! regulation of interleukin-13 production GO:0032656 12 7 0,000 6,319E-03 0,02756542 ! positive regulation of interleukin-4 production GO:0032753 10 7 0,000 6,319E-03 0,02751484 ! molybdopterin cofactor biosynthetic process GO:0032324 10 7 0,000 6,319E-03 0,02746445 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 11 7 0,000 6,319E-03 0,02741424 ! neural tube patterning GO:0021532 8 7 0,000 6,319E-03 0,02736421 ! histone ubiquitination GO:0016574 10 7 0,000 6,319E-03 0,02731437 ! regulation of meiosis GO:0040020 12 7 0,000 6,319E-03 0,02726471 GO:0051445|regulation of meiotic cell cycle, ! eye photoreceptor cell differentiation GO:0001754 14 7 0,000 6,319E-03 0,02721522 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 12 7 0,000 6,319E-03 0,02716592 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 6,319E-03 0,0271168 GO:0002714|positive regulation of B cell mediated immunity, ! mitochondrion morphogenesis GO:0070584 12 7 0,000 6,319E-03 0,02706785 ! regulation of lipid transport GO:0032368 13 7 0,000 6,319E-03 0,02701908 ! regulation of cell division GO:0051302 9 7 0,000 6,319E-03 0,02697048 ! regulation of inflammatory response to antigenic stimulus GO:0002861 14 7 0,000 6,319E-03 0,02692206 ! neutrophil homeostasis GO:0001780 8 7 0,000 6,319E-03 0,02687381 ! regulation of macrophage activation GO:0043030 12 7 0,000 6,319E-03 0,02682574 ! negative regulation of nuclear division GO:0051784 18 7 0,000 6,319E-03 0,02677784 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 6,319E-03 0,0267301 ! diuresis GO:0030146 11 7 0,000 6,319E-03 0,02668254 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 9 7 0,000 6,319E-03 0,02663515 ! positive regulation of epidermis development GO:0045684 11 7 0,000 6,319E-03 0,02658792 ! thiamin metabolic process GO:0006772 8 7 0,000 6,319E-03 0,02654086 ! positive regulation of leukocyte chemotaxis GO:0002690 15 7 0,000 6,319E-03 0,02649397 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of epidermal cell differentiation GO:0045604 10 7 0,000 6,319E-03 0,02644724 ! negative regulation of transmission of nerve impulse GO:0051970 13 7 0,000 6,319E-03 0,02640068 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 6,319E-03 0,02635428 ! dopamine biosynthetic process GO:0042416 15 7 0,000 6,319E-03 0,02630805 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 6,319E-03 0,02626198 ! lymph node development GO:0048535 9 7 0,000 6,319E-03 0,02621606 ! anterior/posterior axis specification GO:0009948 11 7 0,000 6,319E-03 0,02617031 ! negative regulation of viral reproduction GO:0048525 9 7 0,000 6,319E-03 0,02612472 ! regulation of T cell mediated cytotoxicity GO:0001914 15 7 0,000 6,319E-03 0,02607928 ! positive regulation of glucose import GO:0046326 7 7 0,000 6,319E-03 0,02603401 GO:0010828|positive regulation of glucose transport, ! endosome to lysosome transport GO:0008333 11 7 0,000 6,319E-03 0,02598889 ! ATP catabolic process GO:0006200 10 7 0,000 6,319E-03 0,02594392 ! establishment of pigment granule localization GO:0051905 13 7 0,000 6,319E-03 0,02589912 ! positive regulation of fibrinolysis GO:0051919 8 7 0,000 6,319E-03 0,02585446 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 6,319E-03 0,02580996 ! negative regulation of calcium ion transport GO:0051926 8 7 0,000 6,319E-03 0,02576561 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 6,319E-03 0,02572142 ! positive regulation of blood vessel endothelial cell migration GO:0043536 17 7 0,000 6,319E-03 0,02567738 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 6,319E-03 0,02563348 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 6,319E-03 0,02558974 ! muscle adaptation GO:0043500 12 7 0,000 6,319E-03 0,02554615 ! amino sugar catabolic process GO:0046348 9 7 0,000 6,319E-03 0,0255027 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 8 7 0,000 6,319E-03 0,0254594 ! retina homeostasis GO:0001895 9 7 0,000 6,319E-03 0,02541625 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 6,319E-03 0,02537325 ! regulation of growth hormone secretion GO:0060123 14 7 0,000 6,319E-03 0,02533038 ! regulation of T cell receptor signaling pathway GO:0050856 12 7 0,000 6,319E-03 0,02528767 ! positive regulation of microtubule polymerization GO:0031116 12 7 0,000 6,319E-03 0,0252451 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 6,319E-03 0,02520267 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 8 0,000 7,219E-03 0,02874244 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 16 8 0,000 7,219E-03 0,0286943 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 7,219E-03 0,02864631 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 7,219E-03 0,02859849 ! oligosaccharide biosynthetic process GO:0009312 14 8 0,000 7,219E-03 0,02855082 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 8 0,000 7,219E-03 0,02850332 ! negative regulation of cellular catabolic process GO:0031330 10 8 0,000 7,219E-03 0,02845597 ! positive regulation of small GTPase mediated signal transduction GO:0051057 16 8 0,000 7,219E-03 0,02840878 GO:0046579|positive regulation of Ras protein signal transduction, ! generation of neurons in the forebrain GO:0021872 11 8 0,000 7,219E-03 0,02836175 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 7,219E-03 0,02831487 ! cell proliferation in forebrain GO:0021846 10 8 0,000 7,219E-03 0,02826814 ! neutral lipid catabolic process GO:0046461 11 8 0,000 7,219E-03 0,02822157 ! N-glycan processing GO:0006491 12 8 0,000 7,219E-03 0,02817516 ! Golgi to endosome transport GO:0006895 16 8 0,000 7,219E-03 0,02812889 ! glycosaminoglycan catabolic process GO:0006027 11 8 0,000 7,219E-03 0,02808278 ! negative regulation of JAK-STAT cascade GO:0046426 18 8 0,000 7,219E-03 0,02803682 ! mRNA stabilization GO:0048255 16 8 0,000 7,219E-03 0,027991 GO:0043489|RNA stabilization, ! induction of positive chemotaxis GO:0050930 16 8 0,000 7,219E-03 0,02794534 ! neurotransmitter uptake GO:0001504 10 8 0,000 7,219E-03 0,02789983 ! lipoprotein transport GO:0042953 14 8 0,000 7,219E-03 0,02785446 ! membrane hyperpolarization GO:0060081 11 8 0,000 7,219E-03 0,02780924 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 7,219E-03 0,02776417 ! keratinocyte proliferation GO:0043616 15 8 0,000 7,219E-03 0,02771925 ! middle ear morphogenesis GO:0042474 9 8 0,000 7,219E-03 0,02767447 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 7,219E-03 0,02762983 ! amyloid precursor protein catabolic process GO:0042987 13 8 0,000 7,219E-03 0,02758534 ! bile acid and bile salt transport GO:0015721 12 8 0,000 7,219E-03 0,02754099 ! ganglioside metabolic process GO:0001573 16 8 0,000 7,219E-03 0,02749678 ! regulation of mesenchymal cell proliferation GO:0010464 12 8 0,000 7,219E-03 0,02745272 ! reflex GO:0060004 16 8 0,000 7,219E-03 0,02740879 ! positive regulation of isotype switching GO:0045830 16 8 0,000 7,219E-03 0,02736501 GO:0045911|positive regulation of DNA recombination, ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 7,219E-03 0,02732136 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of interleukin-12 biosynthetic process GO:0045075 10 8 0,000 7,219E-03 0,02727786 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 7,219E-03 0,02723449 ! glycerolipid catabolic process GO:0046503 11 8 0,000 7,219E-03 0,02719126 ! positive regulation of chemokine biosynthetic process GO:0045080 9 8 0,000 7,219E-03 0,02714817 ! hemoglobin metabolic process GO:0020027 12 8 0,000 7,219E-03 0,02710521 ! ceramide biosynthetic process GO:0046513 9 8 0,000 7,219E-03 0,02706239 ! nerve growth factor receptor signaling pathway GO:0048011 12 8 0,000 7,219E-03 0,02701971 ! insulin-like growth factor receptor signaling pathway GO:0048009 16 8 0,000 7,219E-03 0,02697716 ! adrenal gland development GO:0030325 18 8 0,000 7,219E-03 0,02693474 ! embryonic cranial skeleton morphogenesis GO:0048701 12 8 0,000 7,219E-03 0,02689246 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 7,219E-03 0,0268503 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 7,219E-03 0,02680829 ! proline metabolic process GO:0006560 9 8 0,000 7,219E-03 0,0267664 ! polyamine biosynthetic process GO:0006596 9 8 0,000 7,219E-03 0,02672464 ! regulation of interleukin-8 biosynthetic process GO:0045414 10 8 0,000 7,219E-03 0,02668301 ! regulation of pigmentation during development GO:0048070 18 8 0,000 7,219E-03 0,02664152 ! central nervous system neuron axonogenesis GO:0021955 16 8 0,000 7,219E-03 0,02660015 GO:0021952|central nervous system projection neuron axonogenesis, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 15 8 0,000 7,219E-03 0,02655891 ! regulation of type I interferon production GO:0032479 8 8 0,000 7,219E-03 0,02651779 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 7,219E-03 0,02647681 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of activated T cell proliferation GO:0042104 19 8 0,000 7,219E-03 0,02643595 ! galactose metabolic process GO:0006012 14 8 0,000 7,219E-03 0,02639521 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 7,219E-03 0,02635461 ! regulation of vascular permeability GO:0043114 12 8 0,000 7,219E-03 0,02631412 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 7,219E-03 0,02627376 ! neurotransmitter catabolic process GO:0042135 16 8 0,000 7,219E-03 0,02623353 ! ruffle organization GO:0031529 12 8 0,000 7,219E-03 0,02619342 ! osteoblast development GO:0002076 14 8 0,000 7,219E-03 0,02615343 ! macroautophagy GO:0016236 14 8 0,000 7,219E-03 0,02611356 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 7,219E-03 0,02607381 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 7,219E-03 0,02603419 ! regulation of Notch signaling pathway GO:0008593 22 8 0,000 7,219E-03 0,02599468 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 7,219E-03 0,02595529 GO:0030204|chondroitin sulfate metabolic process, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 14 8 0,000 7,219E-03 0,02591603 ! G1 DNA damage checkpoint GO:0031571 19 8 0,000 7,219E-03 0,02587688 ! protein retention in ER lumen GO:0006621 16 8 0,000 7,219E-03 0,02583785 ! cardiac muscle cell differentiation GO:0055007 12 8 0,000 7,219E-03 0,02579894 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 8 0,000 7,219E-03 0,02576014 ! regulation of circadian rhythm GO:0042752 13 8 0,000 7,219E-03 0,02572146 ! pigment granule localization GO:0051875 14 8 0,000 7,219E-03 0,0256829 ! positive regulation of cytokine production during immune response GO:0002720 12 8 0,000 7,219E-03 0,02564445 ! antigen processing and presentation of endogenous antigen GO:0019883 14 8 0,000 7,219E-03 0,02560612 ! response to tropane GO:0014073 14 8 0,000 7,219E-03 0,0255679 GO:0042220|response to cocaine, ! positive regulation of systemic arterial blood pressure GO:0003084 12 8 0,000 7,219E-03 0,0255298 ! embryonic axis specification GO:0000578 12 8 0,000 7,219E-03 0,02549181 ! negative regulation of interferon-gamma production GO:0032689 12 8 0,000 7,219E-03 0,02545393 ! negative regulation of systemic arterial blood pressure GO:0003085 18 8 0,000 7,219E-03 0,02541616 ! sphingomyelin metabolic process GO:0006684 11 8 0,000 7,219E-03 0,02537851 ! snRNA metabolic process GO:0016073 10 8 0,000 7,219E-03 0,02534097 GO:0016180|snRNA processing, ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 7,219E-03 0,02530354 ! regulation of focal adhesion formation GO:0051893 17 8 0,000 7,219E-03 0,02526622 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 7,219E-03 0,02522901 ! regulation of mitochondrial membrane potential GO:0051881 14 8 0,000 7,219E-03 0,0251919 ! regulation of interleukin-10 production GO:0032653 12 8 0,000 7,219E-03 0,02515491 ! positive regulation of monooxygenase activity GO:0032770 12 8 0,000 7,219E-03 0,02511803 ! protein import into peroxisome matrix GO:0016558 15 8 0,000 7,219E-03 0,02508125 ! establishment of nucleus localization GO:0040023 14 8 0,000 7,219E-03 0,02504458 ! icosanoid secretion GO:0032309 12 8 0,000 7,219E-03 0,02500802 GO:0050482|arachidonic acid secretion, ! intracellular lipid transport GO:0032365 14 8 0,000 7,219E-03 0,02497157 ! regulation of transcription from RNA polymerase III promoter GO:0006359 11 8 0,000 7,219E-03 0,02493522 ! negative regulation of oxidoreductase activity GO:0051354 13 8 0,000 7,219E-03 0,02489897 ! positive regulation of interleukin-1 beta secretion GO:0050718 10 8 0,000 7,219E-03 0,02486284 ! regulation of T-helper 1 type immune response GO:0002825 10 8 0,000 7,219E-03 0,0248268 ! S phase GO:0051320 8 8 0,000 7,219E-03 0,02479087 GO:0000084|S phase of mitotic cell cycle, ! negative regulation of neuroblast proliferation GO:0007406 25 8 0,000 7,219E-03 0,02475505 ! regulation of macrophage differentiation GO:0045649 15 8 0,000 7,219E-03 0,02471933 ! negative regulation of osteoclast differentiation GO:0045671 12 8 0,000 7,219E-03 0,02468371 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 7,219E-03 0,02464819 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 8 0,000 7,219E-03 0,02461278 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 7,219E-03 0,02457747 ! melanin biosynthetic process GO:0042438 11 8 0,000 7,219E-03 0,02454226 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 7,219E-03 0,02450715 ! regulation of synaptogenesis GO:0051963 12 8 0,000 7,219E-03 0,02447213 ! hormone catabolic process GO:0042447 13 8 0,000 7,219E-03 0,02443722 ! nicotinamide nucleotide biosynthetic process GO:0019359 12 8 0,000 7,219E-03 0,02440241 ! quaternary ammonium group transport GO:0015697 10 8 0,000 7,219E-03 0,0243677 ! positive regulation of ATPase activity GO:0032781 16 8 0,000 7,219E-03 0,02433309 ! trophectodermal cell differentiation GO:0001829 10 8 0,000 7,219E-03 0,02429857 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 7,219E-03 0,02426416 ! regulation of telomere maintenance GO:0032204 10 8 0,000 7,219E-03 0,02422984 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 7,219E-03 0,02419561 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 7,219E-03 0,02416149 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 7,219E-03 0,02412746 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 7,219E-03 0,02409352 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 7,219E-03 0,02405968 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 8 0,000 7,219E-03 0,02402594 ! negative regulation of B cell activation GO:0050869 17 8 0,000 7,219E-03 0,02399229 ! behavioral response to nicotine GO:0035095 13 8 0,000 7,219E-03 0,02395873 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 7,219E-03 0,02392527 GO:0000076|DNA replication checkpoint, ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 7,219E-03 0,0238919 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 16 8 0,000 7,219E-03 0,02385863 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 14 8 0,000 7,219E-03 0,02382544 ! regulation of microtubule polymerization GO:0031113 14 8 0,000 7,219E-03 0,02379235 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 8,118E-03 0,02671786 ! regulation of developmental growth GO:0048638 14 9 0,000 8,118E-03 0,02668085 ! negative regulation of smooth muscle cell proliferation GO:0048662 15 9 0,000 8,118E-03 0,02664395 ! telencephalon cell migration GO:0022029 16 9 0,000 8,118E-03 0,02660715 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 9 0,000 8,118E-03 0,02657045 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 11 9 0,000 8,118E-03 0,02653385 ! negative regulation of lipid biosynthetic process GO:0051055 13 9 0,000 8,118E-03 0,02649735 ! glycerol-3-phosphate metabolic process GO:0006072 11 9 0,000 8,118E-03 0,02646096 ! regulation of cellular amine metabolic process GO:0033238 12 9 0,000 8,118E-03 0,02642466 ! cell volume homeostasis GO:0006884 14 9 0,000 8,118E-03 0,02638846 ! regulation of epidermal growth factor receptor activity GO:0007176 14 9 0,000 8,118E-03 0,02635236 GO:0010469|regulation of receptor activity, ! regulation of smooth muscle cell migration GO:0014910 22 9 0,000 8,118E-03 0,02631636 ! UTP metabolic process GO:0046051 10 9 0,000 8,118E-03 0,02628046 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! prostaglandin biosynthetic process GO:0001516 15 9 0,000 8,118E-03 0,02624465 GO:0046457|prostanoid biosynthetic process, ! succinate metabolic process GO:0006105 16 9 0,000 8,118E-03 0,02620895 ! smoothened signaling pathway GO:0007224 10 9 0,000 8,118E-03 0,02617334 ! protein complex disassembly GO:0043241 17 9 0,000 8,118E-03 0,02613782 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 8,118E-03 0,02610241 ! estrogen metabolic process GO:0008210 16 9 0,000 8,118E-03 0,02606708 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 8,118E-03 0,02603186 ! photoreceptor cell development GO:0042461 17 9 0,000 8,118E-03 0,02599673 GO:0046530|photoreceptor cell differentiation, ! cytoplasmic sequestering of transcription factor GO:0042994 12 9 0,000 8,118E-03 0,02596169 ! negative regulation of muscle cell differentiation GO:0051148 10 9 0,000 8,118E-03 0,02592675 ! microtubule bundle formation GO:0001578 14 9 0,000 8,118E-03 0,0258919 ! T-helper 1 type immune response GO:0042088 13 9 0,000 8,118E-03 0,02585715 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 22 9 0,000 8,118E-03 0,02582249 ! lung alveolus development GO:0048286 18 9 0,000 8,118E-03 0,02578792 ! ciliary or flagellar motility GO:0001539 10 9 0,000 8,118E-03 0,02575344 ! pseudouridine synthesis GO:0001522 10 9 0,000 8,118E-03 0,02571906 ! endothelial cell differentiation GO:0045446 17 9 0,000 8,118E-03 0,02568477 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 8,118E-03 0,02565057 ! regulation of exit from mitosis GO:0007096 12 9 0,000 8,118E-03 0,02561646 ! endoderm development GO:0007492 12 9 0,000 8,118E-03 0,02558244 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 8,118E-03 0,02554851 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 8,118E-03 0,02551467 ! myeloid leukocyte mediated immunity GO:0002444 12 9 0,000 8,118E-03 0,02548092 ! astrocyte differentiation GO:0048708 17 9 0,000 8,118E-03 0,02544726 ! L-phenylalanine metabolic process GO:0006558 11 9 0,000 8,118E-03 0,02541369 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 10 9 0,000 8,118E-03 0,0253802 ! phosphagen metabolic process GO:0006599 12 9 0,000 8,118E-03 0,02534681 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 13 9 0,000 8,118E-03 0,0253135 ! reverse cholesterol transport GO:0043691 17 9 0,000 8,118E-03 0,02528028 ! indolalkylamine metabolic process GO:0006586 15 9 0,000 8,118E-03 0,02524715 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! melanin metabolic process GO:0006582 15 9 0,000 8,118E-03 0,0252141 ! embryonic eye morphogenesis GO:0048048 15 9 0,000 8,118E-03 0,02518114 ! macrophage activation GO:0042116 14 9 0,000 8,118E-03 0,02514827 ! multicellular organism growth GO:0035264 16 9 0,000 8,118E-03 0,02511548 ! retrograde transport, endosome to Golgi GO:0042147 14 9 0,000 8,118E-03 0,02508278 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 8,118E-03 0,02505016 ! neuron apoptosis GO:0051402 12 9 0,000 8,118E-03 0,02501763 ! lens development in camera-type eye GO:0002088 11 9 0,000 8,118E-03 0,02498518 ! positive regulation of vasodilation GO:0045909 14 9 0,000 8,118E-03 0,02495282 ! retinoic acid metabolic process GO:0042573 11 9 0,000 8,118E-03 0,02492054 ! positive regulation of muscle contraction GO:0045933 13 9 0,000 8,118E-03 0,02488834 ! positive regulation of translational initiation GO:0045948 10 9 0,000 8,118E-03 0,02485623 ! regulation of smoothened signaling pathway GO:0008589 15 9 0,000 8,118E-03 0,0248242 ! Schwann cell differentiation GO:0014037 20 9 0,000 8,118E-03 0,02479225 ! acyl-CoA metabolic process GO:0006637 14 9 0,000 8,118E-03 0,02476038 ! regulation of gliogenesis GO:0014013 21 9 0,000 8,118E-03 0,0247286 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 21 9 0,000 8,118E-03 0,02469689 ! oligodendrocyte development GO:0014003 13 9 0,000 8,118E-03 0,02466527 ! alpha-beta T cell differentiation GO:0046632 15 9 0,000 8,118E-03 0,02463373 ! segment specification GO:0007379 11 9 0,000 8,118E-03 0,02460227 ! cellular extravasation GO:0045123 12 9 0,000 8,118E-03 0,02457089 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 8,118E-03 0,02453959 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 13 9 0,000 8,118E-03 0,02450837 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 8,118E-03 0,02447722 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 8,118E-03 0,02444616 ! antigen processing and presentation of exogenous antigen GO:0019884 11 9 0,000 8,118E-03 0,02441518 ! positive regulation of production of molecular mediator of immune response GO:0002702 13 9 0,000 8,118E-03 0,02438427 ! purine nucleoside triphosphate catabolic process GO:0009146 13 9 0,000 8,118E-03 0,02435345 ! regulation of T cell differentiation in the thymus GO:0033081 14 9 0,000 8,118E-03 0,0243227 ! response to amine stimulus GO:0014075 13 9 0,000 8,118E-03 0,02429202 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of protein kinase B signaling cascade GO:0051896 16 9 0,000 8,118E-03 0,02426143 ! erythrocyte development GO:0048821 13 9 0,000 8,118E-03 0,02423091 ! renal water homeostasis GO:0003091 13 9 0,000 8,118E-03 0,02420047 ! positive regulation of tumor necrosis factor production GO:0032760 10 9 0,000 8,118E-03 0,02417011 ! nucleosome disassembly GO:0006337 13 9 0,000 8,118E-03 0,02413982 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! spinal cord motor neuron differentiation GO:0021522 12 9 0,000 8,118E-03 0,02410961 ! transcription from RNA polymerase I promoter GO:0006360 14 9 0,000 8,118E-03 0,02407947 ! induction of an organ GO:0001759 13 9 0,000 8,118E-03 0,02404941 ! leukocyte activation during immune response GO:0002366 15 9 0,000 8,118E-03 0,02401942 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 11 9 0,000 8,118E-03 0,02398951 ! cerebellum morphogenesis GO:0021587 13 9 0,000 8,118E-03 0,02395967 GO:0021696|cerebellar cortex morphogenesis, ! retinal ganglion cell axon guidance GO:0031290 11 9 0,000 8,118E-03 0,02392991 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 8,118E-03 0,02390022 ! sterol catabolic process GO:0016127 11 9 0,000 8,118E-03 0,0238706 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 18 9 0,000 8,118E-03 0,02384106 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 13 9 0,000 8,118E-03 0,02381159 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 14 9 0,000 8,118E-03 0,02378219 ! positive regulation of interleukin-1 secretion GO:0050716 11 9 0,000 8,118E-03 0,02375287 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 8,118E-03 0,02372362 ! negative regulation of cytokine secretion GO:0050710 13 9 0,000 8,118E-03 0,02369443 ! prophase GO:0051324 12 9 0,000 8,118E-03 0,02366533 ! neuroblast proliferation GO:0007405 19 9 0,000 8,118E-03 0,02363629 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 16 9 0,000 8,118E-03 0,02360732 ! peptidyl-threonine modification GO:0018210 22 9 0,000 8,118E-03 0,02357843 ! regulation of interleukin-1 beta secretion GO:0050706 12 9 0,000 8,118E-03 0,0235496 ! ubiquinone metabolic process GO:0006743 11 9 0,000 8,118E-03 0,02352085 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of erythrocyte differentiation GO:0045648 20 9 0,000 8,118E-03 0,02349217 ! acid secretion GO:0046717 14 9 0,000 8,118E-03 0,02346355 ! purine base metabolic process GO:0006144 18 9 0,000 8,118E-03 0,02343501 ! detection of calcium ion GO:0005513 13 9 0,000 8,118E-03 0,02340653 ! myeloid cell homeostasis GO:0002262 10 9 0,000 8,118E-03 0,02337813 ! regulation of fibrinolysis GO:0051917 14 9 0,000 8,118E-03 0,02334979 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 8,118E-03 0,02332152 ! natural killer cell mediated immunity GO:0002228 14 9 0,000 8,118E-03 0,02329332 GO:0042267|natural killer cell mediated cytotoxicity, ! negative regulation of blood vessel endothelial cell migration GO:0043537 18 9 0,000 8,118E-03 0,02326519 ! regulation of muscle adaptation GO:0043502 12 9 0,000 8,118E-03 0,02323712 ! regulation of amino acid transport GO:0051955 11 9 0,000 8,118E-03 0,02320913 ! defense response to Gram-positive bacterium GO:0050830 11 9 0,000 8,118E-03 0,0231812 ! prepulse inhibition GO:0060134 14 9 0,000 8,118E-03 0,02315334 ! sequestering of metal ion GO:0051238 12 9 0,000 8,118E-03 0,02312554 ! lamellipodium assembly GO:0030032 12 9 0,000 8,118E-03 0,02309781 ! regulation of embryonic development GO:0045995 17 9 0,000 8,118E-03 0,02307015 ! mitochondrion localization GO:0051646 15 9 0,000 8,118E-03 0,02304255 ! localization within membrane GO:0051668 15 9 0,000 8,118E-03 0,02301502 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 9,016E-03 0,02553083 ! axon extension GO:0048675 13 10 0,000 9,016E-03 0,0255004 ! neuron fate specification GO:0048665 12 10 0,000 9,016E-03 0,02547004 ! regulation of epithelial cell differentiation GO:0030856 20 10 0,000 9,016E-03 0,02543975 ! cortical actin cytoskeleton organization GO:0030866 24 10 0,000 9,016E-03 0,02540954 ! associative learning GO:0008306 19 10 0,000 9,016E-03 0,0253794 ! positive regulation of B cell proliferation GO:0030890 14 10 0,000 9,016E-03 0,02534933 ! cellular copper ion homeostasis GO:0006878 14 10 0,000 9,016E-03 0,02531933 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 9,016E-03 0,0252894 ! CTP metabolic process GO:0046036 11 10 0,000 9,016E-03 0,02525954 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 17 10 0,000 9,016E-03 0,02522976 ! GTP metabolic process GO:0046039 11 10 0,000 9,016E-03 0,02520004 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 9,016E-03 0,02517039 GO:0007520|myoblast fusion, ! actin-myosin filament sliding GO:0033275 14 10 0,000 9,016E-03 0,02514081 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! hair follicle morphogenesis GO:0031069 17 10 0,000 9,016E-03 0,02511131 ! social behavior GO:0035176 15 10 0,000 9,016E-03 0,02508187 ! sulfate transport GO:0008272 12 10 0,000 9,016E-03 0,0250525 ! regulation of activated T cell proliferation GO:0046006 22 10 0,000 9,016E-03 0,0250232 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 19 10 0,000 9,016E-03 0,02499396 ! artery development GO:0060840 20 10 0,000 9,016E-03 0,0249648 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 13 10 0,000 9,016E-03 0,0249357 ! response to pain GO:0048265 20 10 0,000 9,016E-03 0,02490667 ! COPI coating of Golgi vesicle GO:0048205 15 10 0,000 9,016E-03 0,02487771 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 9,016E-03 0,02484882 ! phospholipid efflux GO:0033700 17 10 0,000 9,016E-03 0,02481999 ! hippocampus development GO:0021766 19 10 0,000 9,016E-03 0,02479123 ! positive regulation of transcription factor import into nucleus GO:0042993 21 10 0,000 9,016E-03 0,02476254 ! amyloid precursor protein metabolic process GO:0042982 16 10 0,000 9,016E-03 0,02473391 ! blood vessel remodeling GO:0001974 23 10 0,000 9,016E-03 0,02470535 ! positive regulation of heart contraction GO:0045823 16 10 0,000 9,016E-03 0,02467685 ! pathogenesis GO:0009405 13 10 0,000 9,016E-03 0,02464842 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 9,016E-03 0,02462006 ! two-component signal transduction system (phosphorelay) GO:0000160 15 10 0,000 9,016E-03 0,02459176 ! negative regulation of striated muscle development GO:0045843 13 10 0,000 9,016E-03 0,02456353 ! protein targeting to ER GO:0045047 21 10 0,000 9,016E-03 0,02453536 ! regulation of S phase of mitotic cell cycle GO:0007090 19 10 0,000 9,016E-03 0,02450725 ! arginine catabolic process GO:0006527 12 10 0,000 9,016E-03 0,02447921 ! melanocyte differentiation GO:0030318 16 10 0,000 9,016E-03 0,02445124 GO:0050931|pigment cell differentiation, ! telomere maintenance via telomerase GO:0007004 14 10 0,000 9,016E-03 0,02442332 GO:0010833|telomere maintenance via telomere lengthening, ! polyamine metabolic process GO:0006595 14 10 0,000 9,016E-03 0,02439548 ! regulation of phosphoprotein phosphatase activity GO:0043666 20 10 0,000 9,016E-03 0,02436769 ! regulation of stress fiber formation GO:0051492 24 10 0,000 9,016E-03 0,02433997 ! positive regulation of endothelial cell migration GO:0010595 20 10 0,000 9,016E-03 0,02431231 ! B cell proliferation GO:0042100 16 10 0,000 9,016E-03 0,02428471 ! nucleobase biosynthetic process GO:0046112 20 10 0,000 9,016E-03 0,02425718 ! mannose metabolic process GO:0006013 11 10 0,000 9,016E-03 0,02422971 ! regulation of sodium ion transport GO:0002028 15 10 0,000 9,016E-03 0,0242023 ! forebrain cell migration GO:0021885 17 10 0,000 9,016E-03 0,02417495 ! lipid digestion GO:0044241 15 10 0,000 9,016E-03 0,02414767 ! substrate-bound cell migration GO:0006929 11 10 0,000 9,016E-03 0,02412044 ! phagocytosis, engulfment GO:0006911 20 10 0,000 9,016E-03 0,02409328 ! receptor clustering GO:0043113 18 10 0,000 9,016E-03 0,02406618 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 9,016E-03 0,02403914 ! UV protection GO:0009650 14 10 0,000 9,016E-03 0,02401216 ! entry into host cell GO:0030260 21 10 0,000 9,016E-03 0,02398524 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of lipoprotein lipase activity GO:0051004 20 10 0,000 9,016E-03 0,02395838 ! behavioral fear response GO:0001662 19 10 0,000 9,016E-03 0,02393158 GO:0002209|behavioral defense response, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 9,016E-03 0,02390484 ! negative regulation of ossification GO:0030279 21 10 0,000 9,016E-03 0,02387816 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 23 10 0,000 9,016E-03 0,02385154 ! protein homotetramerization GO:0051289 20 10 0,000 9,016E-03 0,02382498 ! positive regulation of peptide secretion GO:0002793 16 10 0,000 9,016E-03 0,02379848 ! response to dsRNA GO:0043331 19 10 0,000 9,016E-03 0,02377204 ! DNA ligation GO:0006266 16 10 0,000 9,016E-03 0,02374565 ! phosphoinositide 3-kinase cascade GO:0014065 26 10 0,000 9,016E-03 0,02371933 ! regulation of interleukin-4 production GO:0032673 18 10 0,000 9,016E-03 0,02369306 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 9,016E-03 0,02366685 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 9,016E-03 0,0236407 ! positive regulation of Ras GTPase activity GO:0032320 24 10 0,000 9,016E-03 0,02361461 ! postreplication repair GO:0006301 16 10 0,000 9,016E-03 0,02358857 ! fucose catabolic process GO:0019317 17 10 0,000 9,016E-03 0,02356259 GO:0042355|L-fucose catabolic process, ! mRNA cleavage GO:0006379 14 10 0,000 9,016E-03 0,02353667 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 9,016E-03 0,0235108 ! hindbrain morphogenesis GO:0021575 16 10 0,000 9,016E-03 0,023485 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 10 0,000 9,016E-03 0,02345925 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 13 10 0,000 9,016E-03 0,02343355 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 9,016E-03 0,02340791 ! positive regulation of neuron differentiation GO:0045666 13 10 0,000 9,016E-03 0,02338233 ! positive regulation of leukocyte migration GO:0002687 24 10 0,000 9,016E-03 0,0233568 ! multicellular organismal water homeostasis GO:0050891 14 10 0,000 9,016E-03 0,02333133 ! negative regulation of lymphocyte differentiation GO:0045620 13 10 0,000 9,016E-03 0,02330592 ! methionine biosynthetic process GO:0009086 13 10 0,000 9,016E-03 0,02328056 ! oocyte differentiation GO:0009994 14 10 0,000 9,016E-03 0,02325525 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 14 10 0,000 9,016E-03 0,02323 ! spleen development GO:0048536 17 10 0,000 9,016E-03 0,02320481 ! negative regulation of BMP signaling pathway GO:0030514 15 10 0,000 9,016E-03 0,02317967 ! regulation of RNA splicing GO:0043484 15 10 0,000 9,016E-03 0,02315458 ! positive regulation of viral reproduction GO:0048524 14 10 0,000 9,016E-03 0,02312955 ! blastocyst formation GO:0001825 14 10 0,000 9,016E-03 0,02310457 ! embryonic gut development GO:0048566 13 10 0,000 9,016E-03 0,02307965 ! quinone cofactor metabolic process GO:0042375 12 10 0,000 9,016E-03 0,02305478 ! cerebellar cortex development GO:0021695 14 10 0,000 9,016E-03 0,02302996 ! activation of innate immune response GO:0002218 10 10 0,000 9,016E-03 0,0230052 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 17 10 0,000 9,016E-03 0,02298049 ! insulin secretion GO:0030073 18 10 0,000 9,016E-03 0,02295583 ! cytoplasmic sequestering of protein GO:0051220 15 10 0,000 9,016E-03 0,02293122 ! response to nicotine GO:0035094 18 10 0,000 9,016E-03 0,02290667 ! establishment of cell polarity GO:0030010 12 10 0,000 9,016E-03 0,02288217 ! nucleus localization GO:0051647 16 10 0,000 9,016E-03 0,02285773 ! regulation of synapse organization GO:0050807 14 10 0,000 9,016E-03 0,02283333 ! negative regulation of muscle development GO:0048635 14 11 0,000 9,913E-03 0,02507918 ! positive regulation of glucose metabolic process GO:0010907 17 11 0,000 9,913E-03 0,02505247 ! ER-associated protein catabolic process GO:0030433 17 11 0,000 9,913E-03 0,02502582 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of blood pressure GO:0045776 25 11 0,000 9,913E-03 0,02499922 ! cortical cytoskeleton organization GO:0030865 25 11 0,000 9,913E-03 0,02497268 ! virus-host interaction GO:0019048 20 11 0,000 9,913E-03 0,0249462 ! thyroid gland development GO:0030878 20 11 0,000 9,913E-03 0,02491977 ! pentose-phosphate shunt GO:0006098 14 11 0,000 9,913E-03 0,0248934 GO:0006740|NADPH regeneration, ! regulation of phosphatase activity GO:0010921 23 11 0,000 9,913E-03 0,02486709 ! non-recombinational repair GO:0000726 19 11 0,000 9,913E-03 0,02484083 GO:0006303|double-strand break repair via nonhomologous end joining, ! synapsis GO:0007129 15 11 0,000 9,913E-03 0,02481463 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 11 11 0,000 9,913E-03 0,02478848 ! Golgi vesicle budding GO:0048194 18 11 0,000 9,913E-03 0,02476239 ! elastic fiber assembly GO:0048251 17 11 0,000 9,913E-03 0,02473635 ! regulation of positive chemotaxis GO:0050926 19 11 0,000 9,913E-03 0,02471036 GO:0050927|positive regulation of positive chemotaxis, ! regulation of glycolysis GO:0006110 18 11 0,000 9,913E-03 0,02468444 ! dopamine receptor signaling pathway GO:0007212 25 11 0,000 9,913E-03 0,02465856 ! regulation of cell projection assembly GO:0060491 22 11 0,000 9,913E-03 0,02463274 ! positive regulation of lipid metabolic process GO:0045834 15 11 0,000 9,913E-03 0,02460697 ! bone resorption GO:0045453 16 11 0,000 9,913E-03 0,02458126 ! regulation of chemokine biosynthetic process GO:0045073 13 11 0,000 9,913E-03 0,0245556 ! peptide or protein amino-terminal blocking GO:0018409 16 11 0,000 9,913E-03 0,02453 ! ventral spinal cord development GO:0021517 15 11 0,000 9,913E-03 0,02450444 ! regulated secretory pathway GO:0045055 15 11 0,000 9,913E-03 0,02447895 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 19 11 0,000 9,913E-03 0,0244535 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! regulation of catecholamine secretion GO:0050433 21 11 0,000 9,913E-03 0,02442811 ! syncytium formation GO:0006949 15 11 0,000 9,913E-03 0,02440277 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 9,913E-03 0,02437748 ! glucan biosynthetic process GO:0009250 14 11 0,000 9,913E-03 0,02435224 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 16 11 0,000 9,913E-03 0,02432706 ! Golgi organization GO:0007030 19 11 0,000 9,913E-03 0,02430193 ! response to X-ray GO:0010165 19 11 0,000 9,913E-03 0,02427685 ! retinoic acid receptor signaling pathway GO:0048384 16 11 0,000 9,913E-03 0,02425182 ! adult heart development GO:0007512 12 11 0,000 9,913E-03 0,02422685 ! chondrocyte differentiation GO:0002062 17 11 0,000 9,913E-03 0,02420192 ! epithelial cell development GO:0002064 16 11 0,000 9,913E-03 0,02417705 ! actin cytoskeleton reorganization GO:0031532 20 11 0,000 9,913E-03 0,02415222 ! temperature homeostasis GO:0001659 16 11 0,000 9,913E-03 0,02412745 ! L-glutamate transport GO:0015813 15 11 0,000 9,913E-03 0,02410273 GO:0015800|acidic amino acid transport, ! positive regulation vascular endothelial growth factor production GO:0010575 19 11 0,000 9,913E-03 0,02407806 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 9,913E-03 0,02405344 ! motor axon guidance GO:0008045 17 11 0,000 9,913E-03 0,02402887 ! copper ion homeostasis GO:0055070 15 11 0,000 9,913E-03 0,02400435 ! protein targeting to peroxisome GO:0006625 21 11 0,000 9,913E-03 0,02397988 ! regulation of bone resorption GO:0045124 27 11 0,000 9,913E-03 0,02395546 ! stem cell development GO:0048864 30 11 0,000 9,913E-03 0,0239311 GO:0019827|stem cell maintenance, ! alpha-beta T cell activation GO:0046631 18 11 0,000 9,913E-03 0,02390677 ! negative regulation of axonogenesis GO:0050771 26 11 0,000 9,913E-03 0,0238825 ! regulation of phagocytosis GO:0050764 16 11 0,000 9,913E-03 0,02385828 ! regulation of insulin receptor signaling pathway GO:0046626 17 11 0,000 9,913E-03 0,02383411 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 9,913E-03 0,02380999 ! nucleoside triphosphate catabolic process GO:0009143 16 11 0,000 9,913E-03 0,02378591 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 9,913E-03 0,02376189 ! synaptic vesicle exocytosis GO:0016079 16 11 0,000 9,913E-03 0,02373791 ! regulation of B cell differentiation GO:0045577 23 11 0,000 9,913E-03 0,02371398 ! cranial nerve development GO:0021545 14 11 0,000 9,913E-03 0,0236901 ! nitric oxide metabolic process GO:0046209 15 11 0,000 9,913E-03 0,02366626 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 9,913E-03 0,02364248 ! salivary gland development GO:0007431 24 11 0,000 9,913E-03 0,02361874 ! negative regulation of neurological system process GO:0031645 20 11 0,000 9,913E-03 0,02359505 ! regulation of leukocyte migration GO:0002685 25 11 0,000 9,913E-03 0,02357141 ! musculoskeletal movement GO:0050881 16 11 0,000 9,913E-03 0,02354781 GO:0050879|multicellular organismal movement, ! nitric oxide mediated signal transduction GO:0007263 20 11 0,000 9,913E-03 0,02352427 ! protein-chromophore linkage GO:0018298 13 11 0,000 9,913E-03 0,02350077 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 9,913E-03 0,02347731 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 19 11 0,000 9,913E-03 0,0234539 ! cholesterol efflux GO:0033344 20 11 0,000 9,913E-03 0,02343054 ! digestive tract morphogenesis GO:0048546 16 11 0,000 9,913E-03 0,02340723 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 11 0,000 9,913E-03 0,02338396 ! thyroid hormone metabolic process GO:0042403 17 11 0,000 9,913E-03 0,02336074 ! leukocyte mediated cytotoxicity GO:0001909 18 11 0,000 9,913E-03 0,02333757 ! negative regulation of glucose import GO:0046325 14 11 0,000 9,913E-03 0,02331444 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 21 11 0,000 9,913E-03 0,02329135 ! regulation of organic acid transport GO:0032890 17 11 0,000 9,913E-03 0,02326832 ! regulation of actin filament bundle formation GO:0032231 25 11 0,000 9,913E-03 0,02324532 ! cardiac cell differentiation GO:0035051 18 11 0,000 9,913E-03 0,02322238 ! defense response to fungus GO:0050832 13 11 0,000 9,913E-03 0,02319947 ! lysogeny GO:0030069 20 11 0,000 9,913E-03 0,02317662 GO:0019047|provirus integration, ! T cell receptor signaling pathway GO:0050852 22 11 0,000 9,913E-03 0,02315381 ! acrosome reaction GO:0007340 14 11 0,000 9,913E-03 0,02313104 ! regulation of synapse structure and activity GO:0050803 15 11 0,000 9,913E-03 0,02310832 ! regulation of steroid biosynthetic process GO:0050810 13 11 0,000 9,913E-03 0,02308564 ! rRNA transcription GO:0009303 19 12 0,000 0,01080989 0,0251489 ! reproductive cellular process GO:0048610 15 12 0,000 0,01080989 0,02512427 ! regulation of membrane protein ectodomain proteolysis GO:0051043 17 12 0,000 0,01080989 0,02509969 ! pteridine and derivative biosynthetic process GO:0042559 15 12 0,000 0,01080989 0,02507515 ! dicarboxylic acid transport GO:0006835 21 12 0,000 0,01080989 0,02505066 ! phosphate transport GO:0006817 15 12 0,000 0,01080989 0,02502622 ! positive regulation of GTPase activity GO:0043547 29 12 0,000 0,01080989 0,02500183 ! peroxisomal transport GO:0043574 22 12 0,000 0,01080989 0,02497749 ! mating GO:0007618 16 12 0,000 0,01080989 0,02495319 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01080989 0,02492894 ! heart looping GO:0001947 15 12 0,000 0,01080989 0,02490474 ! negative regulation of cell-matrix adhesion GO:0001953 31 12 0,000 0,01080989 0,02488058 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 20 12 0,000 0,01080989 0,02485647 ! negative regulation of proteolysis GO:0045861 17 12 0,000 0,01080989 0,02483241 ! T cell selection GO:0045058 25 12 0,000 0,01080989 0,02480839 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01080989 0,02478442 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 17 12 0,000 0,01080989 0,0247605 ! oligodendrocyte differentiation GO:0048709 19 12 0,000 0,01080989 0,02473662 ! plasma membrane organization GO:0007009 19 12 0,000 0,01080989 0,02471279 ! focal adhesion formation GO:0048041 28 12 0,000 0,01080989 0,02468901 ! mitotic spindle organization GO:0007052 16 12 0,000 0,01080989 0,02466527 ! cellular carbohydrate catabolic process GO:0044275 14 12 0,000 0,01080989 0,02464158 ! regulation of intracellular pH GO:0051453 19 12 0,000 0,01080989 0,02461793 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01080989 0,02459432 ! monoamine transport GO:0015844 14 12 0,000 0,01080989 0,02457077 ! regulation of vascular endothelial growth factor production GO:0010574 20 12 0,000 0,01080989 0,02454725 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 18 12 0,000 0,01080989 0,02452379 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01080989 0,02450036 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01080989 0,02447698 ! regulation of organ growth GO:0046620 14 12 0,000 0,01080989 0,02445365 ! vasoconstriction GO:0042310 18 12 0,000 0,01080989 0,02443036 ! RNA-dependent DNA replication GO:0006278 16 12 0,000 0,01080989 0,02440712 ! regulation of interleukin-8 production GO:0032677 19 12 0,000 0,01080989 0,02438392 ! regulation of Rho GTPase activity GO:0032319 22 12 0,000 0,01080989 0,02436076 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01080989 0,02433765 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01080989 0,02431458 ! histone deacetylation GO:0016575 14 12 0,000 0,01080989 0,02429155 ! histone acetylation GO:0016573 27 12 0,000 0,01080989 0,02426857 ! DNA methylation GO:0006306 19 12 0,000 0,01080989 0,02424563 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 19 12 0,000 0,01080989 0,02422274 ! protein sumoylation GO:0016925 14 12 0,000 0,01080989 0,02419989 ! chromatin silencing GO:0006342 23 12 0,000 0,01080989 0,02417708 ! negative regulation of MAPKKK cascade GO:0043409 23 12 0,000 0,01080989 0,02415431 ! gland morphogenesis GO:0022612 24 12 0,000 0,01080989 0,02413159 ! regulation of hormone metabolic process GO:0032350 21 12 0,000 0,01080989 0,02410891 ! zymogen activation GO:0031638 16 12 0,000 0,01080989 0,02408627 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01080989 0,02406368 ! nucleosome positioning GO:0016584 13 12 0,000 0,01080989 0,02404112 ! T cell homeostasis GO:0043029 22 12 0,000 0,01080989 0,02401861 ! regulation of isotype switching GO:0045191 22 12 0,000 0,01080989 0,02399615 ! glutathione biosynthetic process GO:0006750 14 12 0,000 0,01080989 0,02397372 ! response to gamma radiation GO:0010332 21 12 0,000 0,01080989 0,02395133 ! regulation of osteoclast differentiation GO:0045670 18 12 0,000 0,01080989 0,02392899 ! regulation of T-helper 2 cell differentiation GO:0045628 19 12 0,000 0,01080989 0,02390669 ! aromatic amino acid family catabolic process GO:0009074 16 12 0,000 0,01080989 0,02388443 ! serine family amino acid biosynthetic process GO:0009070 16 12 0,000 0,01080989 0,02386221 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01080989 0,02384004 ! male genitalia development GO:0030539 15 12 0,000 0,01080989 0,0238179 ! regulation of cellular carbohydrate catabolic process GO:0043471 19 12 0,000 0,01080989 0,02379581 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of fatty acid oxidation GO:0046320 20 12 0,000 0,01080989 0,02377375 ! establishment or maintenance of apical/basal cell polarity GO:0035088 23 12 0,000 0,01080989 0,02375174 ! developmental induction GO:0031128 16 12 0,000 0,01080989 0,02372977 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 15 12 0,000 0,01080989 0,02370784 ! response to cold GO:0009409 15 12 0,000 0,01080989 0,02368595 ! negative regulation of immune effector process GO:0002698 20 12 0,000 0,01080989 0,0236641 ! respiratory burst GO:0045730 22 13 0,000 0,01170572 0,02560154 ! lactation GO:0007595 22 13 0,000 0,01170572 0,02557797 ! tRNA modification GO:0006400 15 13 0,000 0,01170572 0,02555444 ! negative regulation of cell projection organization GO:0031345 29 13 0,000 0,01170572 0,02553095 ! positive regulation of blood pressure GO:0045777 19 13 0,000 0,01170572 0,0255075 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01170572 0,0254841 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 20 13 0,000 0,01170572 0,02546075 ! water transport GO:0006833 21 13 0,000 0,01170572 0,02543743 GO:0042044|fluid transport, ! regulation of B cell proliferation GO:0030888 24 13 0,000 0,01170572 0,02541416 ! regulation of nitric-oxide synthase activity GO:0050999 23 13 0,000 0,01170572 0,02539093 ! copper ion transport GO:0006825 15 13 0,000 0,01170572 0,02536774 ! filopodium assembly GO:0046847 21 13 0,000 0,01170572 0,02534459 ! lipid localization GO:0010876 25 13 0,000 0,01170572 0,02532149 GO:0019915|lipid storage, ! detection of mechanical stimulus GO:0050982 17 13 0,000 0,01170572 0,02529843 ! negative regulation of transcription factor import into nucleus GO:0042992 26 13 0,000 0,01170572 0,02527541 ! cytokine biosynthetic process GO:0042089 17 13 0,000 0,01170572 0,02525243 ! T cell proliferation GO:0042098 24 13 0,000 0,01170572 0,02522949 ! organelle fusion GO:0048284 29 13 0,000 0,01170572 0,0252066 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01170572 0,02518375 ! endocrine pancreas development GO:0031018 19 13 0,000 0,01170572 0,02516094 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 24 13 0,000 0,01170572 0,02513817 ! platelet-derived growth factor receptor signaling pathway GO:0048008 20 13 0,000 0,01170572 0,02511544 ! photoreceptor cell maintenance GO:0045494 20 13 0,000 0,01170572 0,02509275 ! regulation of mRNA processing GO:0050684 21 13 0,000 0,01170572 0,0250701 ! regulation of skeletal muscle fiber development GO:0048742 22 13 0,000 0,01170572 0,0250475 ! methionine metabolic process GO:0006555 16 13 0,000 0,01170572 0,02502493 ! deoxyribonucleotide catabolic process GO:0009264 17 13 0,000 0,01170572 0,02500241 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01170572 0,02497992 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 21 13 0,000 0,01170572 0,02495748 ! negative regulation of endothelial cell migration GO:0010596 22 13 0,000 0,01170572 0,02493507 ! membrane protein proteolysis GO:0033619 21 13 0,000 0,01170572 0,02491271 GO:0006509|membrane protein ectodomain proteolysis, ! fear response GO:0042596 22 13 0,000 0,01170572 0,02489039 ! neutral amino acid transport GO:0015804 20 13 0,000 0,01170572 0,0248681 ! negative regulation of mitotic cell cycle GO:0045930 32 13 0,000 0,01170572 0,02484586 ! regulation of natural killer cell mediated immunity GO:0002715 21 13 0,000 0,01170572 0,02482366 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 16 13 0,000 0,01170572 0,02480149 ! positive regulation of protein import into nucleus GO:0042307 24 13 0,000 0,01170572 0,02477937 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01170572 0,02475728 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01170572 0,02473524 ! cellular pigmentation GO:0033059 24 13 0,000 0,01170572 0,02471323 ! histone methylation GO:0016571 16 13 0,000 0,01170572 0,02469126 ! regulation of epidermis development GO:0045682 21 13 0,000 0,01170572 0,02466934 ! oxygen transport GO:0015671 20 13 0,000 0,01170572 0,02464745 ! regulation of axon extension GO:0030516 26 13 0,000 0,01170572 0,0246256 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 24 13 0,000 0,01170572 0,02460378 ! detection of bacterium GO:0016045 13 13 0,000 0,01170572 0,02458201 ! L-fucose metabolic process GO:0042354 21 13 0,000 0,01170572 0,02456028 ! regulation of NF-kappaB import into nucleus GO:0042345 24 13 0,000 0,01170572 0,02453858 ! positive regulation of homeostatic process GO:0032846 19 13 0,000 0,01170572 0,02451692 ! positive regulation of protein polymerization GO:0032273 21 13 0,000 0,01170572 0,0244953 ! actin filament polymerization GO:0030041 18 13 0,000 0,01170572 0,02447372 ! regulation of protein ubiquitination GO:0031396 20 14 0,000 0,01260078 0,02632187 ! N-terminal protein amino acid modification GO:0031365 20 14 0,000 0,01260078 0,02629872 ! positive regulation of cellular catabolic process GO:0031331 24 14 0,000 0,01260078 0,02627561 ! G1 phase of mitotic cell cycle GO:0000080 24 14 0,000 0,01260078 0,02625254 ! neuron maturation GO:0042551 24 14 0,000 0,01260078 0,02622952 ! regulation of S phase GO:0033261 25 14 0,000 0,01260078 0,02620653 ! regulation of chemokine production GO:0032642 18 14 0,000 0,01260078 0,02618358 ! myotube differentiation GO:0014902 21 14 0,000 0,01260078 0,02616067 ! double-strand break repair via homologous recombination GO:0000724 24 14 0,000 0,01260078 0,0261378 GO:0000725|recombinational repair, ! negative regulation of bone remodeling GO:0046851 28 14 0,000 0,01260078 0,02611498 ! phospholipid catabolic process GO:0009395 19 14 0,000 0,01260078 0,02609219 ! aminoglycan catabolic process GO:0006026 19 14 0,000 0,01260078 0,02606944 ! vesicle targeting, to, from or within Golgi GO:0048199 19 14 0,000 0,01260078 0,02604673 ! cardiac muscle contraction GO:0060048 28 14 0,000 0,01260078 0,02602406 ! RNA polyadenylation GO:0043631 21 14 0,000 0,01260078 0,02600143 ! cartilage condensation GO:0001502 22 14 0,000 0,01260078 0,02597884 ! gene silencing by RNA GO:0031047 22 14 0,000 0,01260078 0,02595629 ! response to cAMP GO:0051591 20 14 0,000 0,01260078 0,02593378 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 17 14 0,000 0,01260078 0,02591131 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 14 0,000 0,01260078 0,02588887 ! negative regulation of cytokine biosynthetic process GO:0042036 19 14 0,000 0,01260078 0,02586648 ! limbic system development GO:0021761 25 14 0,000 0,01260078 0,02584412 ! positive regulation of ion transport GO:0043270 18 14 0,000 0,01260078 0,0258218 GO:0051928|positive regulation of calcium ion transport, ! startle response GO:0001964 21 14 0,000 0,01260078 0,02579952 ! palate development GO:0060021 19 14 0,000 0,01260078 0,02577728 ! negative regulation of gene expression, epigenetic GO:0045814 30 14 0,000 0,01260078 0,02575508 ! negative regulation of protein amino acid phosphorylation GO:0001933 31 14 0,000 0,01260078 0,02573292 ! regulation of defense response to virus GO:0050688 26 14 0,000 0,01260078 0,02571079 ! response to hexose stimulus GO:0009746 22 14 0,000 0,01260078 0,0256887 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! epidermis morphogenesis GO:0048730 31 14 0,000 0,01260078 0,02566665 ! arginine metabolic process GO:0006525 17 14 0,000 0,01260078 0,02564464 ! glutamate metabolic process GO:0006536 21 14 0,000 0,01260078 0,02562266 ! glycine metabolic process GO:0006544 22 14 0,000 0,01260078 0,02560073 ! pituitary gland development GO:0021983 24 14 0,000 0,01260078 0,02557883 ! tyrosine metabolic process GO:0006570 20 14 0,000 0,01260078 0,02555696 ! negative regulation of microtubule depolymerization GO:0007026 34 14 0,000 0,01260078 0,02553514 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 21 14 0,000 0,01260078 0,02551335 ! cytokine metabolic process GO:0042107 18 14 0,000 0,01260078 0,0254916 ! NAD metabolic process GO:0019674 25 14 0,000 0,01260078 0,02546989 ! regulation of ion transmembrane transporter activity GO:0032412 19 14 0,000 0,01260078 0,02544821 ! regulation of heart rate GO:0002027 26 14 0,000 0,01260078 0,02542657 ! exocrine system development GO:0035272 29 14 0,000 0,01260078 0,02540497 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,01260078 0,0253834 ! positive regulation of carbohydrate metabolic process GO:0045913 22 14 0,000 0,01260078 0,02536187 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! purine nucleoside monophosphate metabolic process GO:0009126 22 14 0,000 0,01260078 0,02534038 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 25 14 0,000 0,01260078 0,02531892 ! axon cargo transport GO:0008088 29 14 0,000 0,01260078 0,0252975 ! positive regulation of T cell mediated immunity GO:0002711 30 14 0,000 0,01260078 0,02527612 ! negative regulation of protein import into nucleus GO:0042308 27 14 0,000 0,01260078 0,02525477 ! genitalia development GO:0048806 18 14 0,000 0,01260078 0,02523346 ! regulation of interleukin-12 production GO:0032655 20 14 0,000 0,01260078 0,02521218 ! autonomic nervous system development GO:0048483 26 14 0,000 0,01260078 0,02519094 ! tissue regeneration GO:0042246 24 14 0,000 0,01260078 0,02516974 ! negative regulation of protein secretion GO:0050709 22 14 0,000 0,01260078 0,02514857 ! water homeostasis GO:0030104 23 14 0,000 0,01260078 0,02512744 ! cofactor transport GO:0051181 22 14 0,000 0,01260078 0,02510634 ! regulation of acute inflammatory response GO:0002673 21 14 0,000 0,01260078 0,02508527 ! positive regulation of T-helper cell differentiation GO:0045624 20 14 0,000 0,01260078 0,02506425 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01260078 0,02504326 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01260078 0,0250223 ! regulation of mRNA stability GO:0043488 30 14 0,000 0,01260078 0,02500138 ! cell killing GO:0001906 22 14 0,000 0,01260078 0,02498049 ! positive regulation of JNK cascade GO:0046330 22 14 0,000 0,01260078 0,02495964 ! epithelial to mesenchymal transition GO:0001837 24 14 0,000 0,01260078 0,02493882 ! negative regulation of mast cell proliferation GO:0070667 26 14 0,000 0,01260078 0,02491804 GO:0042130|negative regulation of T cell proliferation, ! mRNA 3'-end processing GO:0031124 21 14 0,000 0,01260078 0,02489729 ! microspike assembly GO:0030035 25 14 0,000 0,01260078 0,02487658 ! positive regulation of calcium-mediated signaling GO:0050850 27 14 0,000 0,01260078 0,0248559 ! regulation of skeletal muscle tissue development GO:0048641 24 15 0,000 0,01349507 0,02659785 ! superoxide anion generation GO:0042554 19 15 0,000 0,01349507 0,02657577 ! negative regulation of hormone secretion GO:0046888 22 15 0,000 0,01349507 0,02655374 ! skin development GO:0043588 28 15 0,000 0,01349507 0,02653174 ! embryonic hindlimb morphogenesis GO:0035116 28 15 0,000 0,01349507 0,02650977 ! embryonic forelimb morphogenesis GO:0035115 18 15 0,000 0,01349507 0,02648785 ! inositol metabolic process GO:0006020 21 15 0,000 0,01349507 0,02646596 ! retina development in camera-type eye GO:0060041 22 15 0,000 0,01349507 0,0264441 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 22 15 0,000 0,01349507 0,02642228 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 25 15 0,000 0,01349507 0,0264005 ! regulation of transmembrane transporter activity GO:0022898 20 15 0,000 0,01349507 0,02637875 GO:0032409|regulation of transporter activity, ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,01349507 0,02635704 ! activation of MAPKK activity GO:0000186 22 15 0,000 0,01349507 0,02633537 ! induction of apoptosis via death domain receptors GO:0008625 19 15 0,000 0,01349507 0,02631373 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 18 15 0,000 0,01349507 0,02629212 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01349507 0,02627055 ! response to osmotic stress GO:0006970 23 15 0,000 0,01349507 0,02624902 ! vesicle coating GO:0006901 26 15 0,000 0,01349507 0,02622752 ! regulation of the force of heart contraction GO:0002026 24 15 0,000 0,01349507 0,02620606 ! preassembly of GPI anchor in ER membrane GO:0016254 22 15 0,000 0,01349507 0,02618463 ! positive regulation of activation of JAK2 kinase activity GO:0010535 15 15 0,000 0,01349507 0,02616324 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 23 15 0,000 0,01349507 0,02614188 ! bone mineralization GO:0030282 17 15 0,000 0,01349507 0,02612056 ! G1/S transition checkpoint GO:0031575 36 15 0,000 0,01349507 0,02609927 ! intermediate filament cytoskeleton organization GO:0045104 27 15 0,000 0,01349507 0,02607802 ! positive regulation of axonogenesis GO:0050772 21 15 0,000 0,01349507 0,0260568 ! regulation of cytokine production during immune response GO:0002718 23 15 0,000 0,01349507 0,02603561 ! T cell differentiation in the thymus GO:0033077 30 15 0,000 0,01349507 0,02601446 ! regulation of cellular pH GO:0030641 23 15 0,000 0,01349507 0,02599335 ! ribosome assembly GO:0042255 17 15 0,000 0,01349507 0,02597227 ! cerebellum development GO:0021549 19 15 0,000 0,01349507 0,02595122 ! regulation of monooxygenase activity GO:0032768 29 15 0,000 0,01349507 0,02593021 ! mRNA splice site selection GO:0006376 33 15 0,000 0,01349507 0,02590923 ! positive regulation of cytokine secretion GO:0050715 19 15 0,000 0,01349507 0,02588828 ! regulation of T-helper 2 type immune response GO:0002828 24 15 0,000 0,01349507 0,02586737 ! negative regulation of inflammatory response GO:0050728 18 15 0,000 0,01349507 0,02584649 ! sphingolipid catabolic process GO:0030149 27 15 0,000 0,01349507 0,02582565 GO:0046466|membrane lipid catabolic process, ! positive regulation of bone mineralization GO:0030501 22 15 0,000 0,01349507 0,02580484 ! regulation of erythrocyte differentiation GO:0045646 29 15 0,000 0,01349507 0,02578406 ! muscle maintenance GO:0046716 21 15 0,000 0,01349507 0,02576332 ! C21-steroid hormone biosynthetic process GO:0006700 17 15 0,000 0,01349507 0,02574261 ! activation of NF-kappaB-inducing kinase activity GO:0007250 23 15 0,000 0,01349507 0,02572193 ! intestinal absorption GO:0050892 22 15 0,000 0,01349507 0,02570129 ! regulation of ATPase activity GO:0043462 24 15 0,000 0,01349507 0,02568068 ! dopamine metabolic process GO:0042417 32 15 0,000 0,01349507 0,0256601 ! gas transport GO:0015669 23 15 0,000 0,01349507 0,02563956 ! regulation of RNA stability GO:0043487 31 15 0,000 0,01349507 0,02561904 ! organic cation transport GO:0015695 19 15 0,000 0,01349507 0,02559857 ! heme biosynthetic process GO:0006783 22 15 0,000 0,01349507 0,02557812 ! regulation of BMP signaling pathway GO:0030510 24 15 0,000 0,01349507 0,02555771 ! lymphocyte homeostasis GO:0002260 29 15 0,000 0,01349507 0,02553733 ! aromatic compound biosynthetic process GO:0019438 18 15 0,000 0,01349507 0,02551698 ! release of cytochrome c from mitochondria GO:0001836 29 15 0,000 0,01349507 0,02549666 ! cilium assembly GO:0042384 22 15 0,000 0,01349507 0,02547638 ! regulation of calcium-mediated signaling GO:0050848 28 15 0,000 0,01349507 0,02545613 ! inner ear receptor cell differentiation GO:0060113 30 15 0,000 0,01349507 0,02543591 ! peptide hormone processing GO:0016486 23 15 0,000 0,01349507 0,02541572 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 36 15 0,000 0,01349507 0,02539556 ! sulfur amino acid biosynthetic process GO:0000097 21 16 0,000 0,0143886 0,02705559 ! bone remodeling GO:0046849 24 16 0,000 0,0143886 0,02703416 ! negative regulation of nucleocytoplasmic transport GO:0046823 29 16 0,000 0,0143886 0,02701278 ! positive regulation of nucleocytoplasmic transport GO:0046824 28 16 0,000 0,0143886 0,02699142 ! regulation of cell-cell adhesion GO:0022407 38 16 0,000 0,0143886 0,0269701 ! bile acid metabolic process GO:0008206 23 16 0,000 0,0143886 0,02694882 ! axis specification GO:0009798 26 16 0,000 0,0143886 0,02692756 ! negative regulation of endothelial cell proliferation GO:0001937 33 16 0,000 0,0143886 0,02690634 ! mitotic chromosome condensation GO:0007076 26 16 0,000 0,0143886 0,02688516 ! positive regulation of cell growth GO:0030307 22 16 0,000 0,0143886 0,026864 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,0143886 0,02684288 ! centrosome cycle GO:0007098 18 16 0,000 0,0143886 0,0268218 ! cell differentiation in spinal cord GO:0021515 24 16 0,000 0,0143886 0,02680074 ! regulation of survival gene product expression GO:0045884 23 16 0,000 0,0143886 0,02677972 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 16 0,000 0,0143886 0,02675874 ! cellular response to starvation GO:0009267 26 16 0,000 0,0143886 0,02673778 ! DNA integration GO:0015074 25 16 0,000 0,0143886 0,02671686 ! branching involved in ureteric bud morphogenesis GO:0001658 24 16 0,000 0,0143886 0,02669597 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 35 16 0,000 0,0143886 0,02667512 ! regulation of exocytosis GO:0017157 28 16 0,000 0,0143886 0,02665429 ! embryonic digit morphogenesis GO:0042733 20 16 0,000 0,0143886 0,0266335 ! positive regulation of biomineral formation GO:0070169 23 16 0,000 0,0143886 0,02661274 ! regulation of vasodilation GO:0042312 26 16 0,000 0,0143886 0,02659202 ! DNA replication initiation GO:0006270 26 16 0,000 0,0143886 0,02657132 ! DNA unwinding during replication GO:0006268 24 16 0,000 0,0143886 0,02655066 ! regulation of steroid metabolic process GO:0019218 23 16 0,000 0,0143886 0,02653003 ! neuron recognition GO:0008038 27 16 0,000 0,0143886 0,02650943 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 22 16 0,000 0,0143886 0,02648887 ! G1 phase GO:0051318 28 16 0,000 0,0143886 0,02646833 ! cellular amino acid derivative catabolic process GO:0042219 31 16 0,000 0,0143886 0,02644783 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,0143886 0,02642736 GO:0006626|protein targeting to mitochondrion, ! positive regulation of oxidoreductase activity GO:0051353 22 16 0,000 0,0143886 0,02640692 ! negative regulation of blood coagulation GO:0030195 21 16 0,000 0,0143886 0,02638651 ! negative regulation of tissue remodeling GO:0034104 35 16 0,000 0,0143886 0,02636614 ! NADP metabolic process GO:0006739 22 16 0,000 0,0143886 0,02634579 ! neuromuscular synaptic transmission GO:0007274 31 16 0,000 0,0143886 0,02632548 ! synaptic transmission, cholinergic GO:0007271 24 16 0,000 0,0143886 0,0263052 ! folic acid and derivative metabolic process GO:0006760 18 16 0,000 0,0143886 0,02628495 ! regulation of T-helper cell differentiation GO:0045622 25 16 0,000 0,0143886 0,02626473 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,0143886 0,02624454 ! aspartate family amino acid biosynthetic process GO:0009067 19 16 0,000 0,0143886 0,02622438 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 24 16 0,000 0,0143886 0,02620426 ! positive regulation of neuron apoptosis GO:0043525 30 16 0,000 0,0143886 0,02618416 ! regulation of blood vessel endothelial cell migration GO:0043535 37 16 0,000 0,0143886 0,0261641 ! RNA 3'-end processing GO:0031123 23 16 0,000 0,0143886 0,02614406 ! defense response to virus GO:0051607 28 16 0,000 0,0143886 0,02612406 ! peptide hormone secretion GO:0030072 26 16 0,000 0,0143886 0,02610409 ! positive regulation of protein complex assembly GO:0031334 26 17 0,000 0,01528136 0,02770258 ! regulation of lipid biosynthetic process GO:0046890 22 17 0,000 0,01528136 0,02768143 ! negative regulation of cell cycle process GO:0010948 37 17 0,000 0,01528136 0,02766032 ! zinc ion transport GO:0006829 22 17 0,000 0,01528136 0,02763924 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,01528136 0,02761819 ! protein amino acid deacetylation GO:0006476 23 17 0,000 0,01528136 0,02759717 ! heterophilic cell adhesion GO:0007157 38 17 0,000 0,01528136 0,02757618 ! protein amino acid acetylation GO:0006473 33 17 0,000 0,01528136 0,02755523 ! regulation of neurotransmitter secretion GO:0046928 32 17 0,000 0,01528136 0,0275343 ! forelimb morphogenesis GO:0035136 20 17 0,000 0,01528136 0,02751341 ! negative regulation of ion transport GO:0043271 19 17 0,000 0,01528136 0,02749255 ! regulation of muscle cell differentiation GO:0051147 26 17 0,000 0,01528136 0,02747173 ! adult walking behavior GO:0007628 30 17 0,000 0,01528136 0,02745093 ! patterning of blood vessels GO:0001569 27 17 0,000 0,01528136 0,02743016 ! mechanoreceptor differentiation GO:0042490 32 17 0,000 0,01528136 0,02740943 ! cellular response to hydrogen peroxide GO:0070301 25 17 0,000 0,01528136 0,02738873 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 25 17 0,000 0,01528136 0,02736806 ! retinoid metabolic process GO:0001523 22 17 0,000 0,01528136 0,02734742 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 26 17 0,000 0,01528136 0,02732681 ! positive regulation of proteolysis GO:0045862 21 17 0,000 0,01528136 0,02730623 ! cardiac muscle tissue development GO:0048738 27 17 0,000 0,01528136 0,02728569 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01528136 0,02726517 ! protein polyubiquitination GO:0000209 31 17 0,000 0,01528136 0,02724469 ! cerebral cortex development GO:0021987 34 17 0,000 0,01528136 0,02722423 ! complement activation, alternative pathway GO:0006957 17 17 0,000 0,01528136 0,02720381 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01528136 0,02718342 ! fructose metabolic process GO:0006000 24 17 0,000 0,01528136 0,02716305 ! membrane budding GO:0006900 30 17 0,000 0,01528136 0,02714272 ! neuromuscular junction development GO:0007528 25 17 0,000 0,01528136 0,02712242 ! L-amino acid transport GO:0015807 27 17 0,000 0,01528136 0,02710215 ! regulation of protein binding GO:0043393 29 17 0,000 0,01528136 0,02708191 ! peptide secretion GO:0002790 30 17 0,000 0,01528136 0,0270617 ! stem cell differentiation GO:0048863 40 17 0,000 0,01528136 0,02704152 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,01528136 0,02702137 ! intermediate filament-based process GO:0045103 29 17 0,000 0,01528136 0,02700125 ! protein export from nucleus GO:0006611 26 17 0,000 0,01528136 0,02698116 ! nucleotide-excision repair, DNA gap filling GO:0006297 23 17 0,000 0,01528136 0,0269611 ! diencephalon development GO:0021536 27 17 0,000 0,01528136 0,02694107 ! oogenesis GO:0048477 25 17 0,000 0,01528136 0,02692107 ! long-chain fatty acid transport GO:0015909 25 17 0,000 0,01528136 0,0269011 ! peptide biosynthetic process GO:0043043 22 17 0,000 0,01528136 0,02688115 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,01528136 0,02686124 GO:0046467|membrane lipid biosynthetic process, ! biomineral formation GO:0031214 21 17 0,000 0,01528136 0,02684136 ! vitamin A metabolic process GO:0006776 23 17 0,000 0,01528136 0,02682151 ! steroid catabolic process GO:0006706 24 17 0,000 0,01528136 0,02680168 ! porphyrin biosynthetic process GO:0006779 24 17 0,000 0,01528136 0,02678189 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 23 17 0,000 0,01528136 0,02676212 ! nerve development GO:0021675 20 17 0,000 0,01528136 0,02674239 ! negative regulation of homeostatic process GO:0032845 29 17 0,000 0,01528136 0,02672268 ! regulation of mitotic metaphase/anaphase transition GO:0030071 33 17 0,000 0,01528136 0,026703 ! protein secretion GO:0009306 32 18 0,000 0,01617336 0,02824091 ! regulation of glucose metabolic process GO:0010906 25 18 0,000 0,01617336 0,02822014 ! positive regulation of cell killing GO:0031343 27 18 0,000 0,01617336 0,02819941 ! negative regulation of defense response GO:0031348 21 18 0,000 0,01617336 0,0281787 ! pteridine and derivative metabolic process GO:0042558 23 18 0,000 0,01617336 0,02815803 ! positive regulation of anti-apoptosis GO:0045768 33 18 0,000 0,01617336 0,02813739 ! metencephalon development GO:0022037 25 18 0,000 0,01617336 0,02811677 ! positive regulation of hormone secretion GO:0046887 28 18 0,000 0,01617336 0,02809619 ! hormone secretion GO:0046879 28 18 0,000 0,01617336 0,02807564 ! 2'-deoxyribonucleotide metabolic process GO:0009394 24 18 0,000 0,01617336 0,02805511 GO:0019692|deoxyribose phosphate metabolic process, ! signal complex assembly GO:0007172 32 18 0,000 0,01617336 0,02803462 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 27 18 0,000 0,01617336 0,02801416 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,01617336 0,02799372 ! intra-Golgi vesicle-mediated transport GO:0006891 28 18 0,000 0,01617336 0,02797332 ! protein amino acid ADP-ribosylation GO:0006471 30 18 0,000 0,01617336 0,02795295 ! cAMP metabolic process GO:0046058 33 18 0,000 0,01617336 0,0279326 ! transcription from RNA polymerase III promoter GO:0006383 36 18 0,000 0,01617336 0,02791229 ! regulation of postsynaptic membrane potential GO:0060078 31 18 0,000 0,01617336 0,027892 ! glial cell development GO:0021782 31 18 0,000 0,01617336 0,02787175 ! keratinization GO:0031424 19 18 0,000 0,01617336 0,02785152 ! regulation of systemic arterial blood pressure by hormone GO:0001990 27 18 0,000 0,01617336 0,02783132 GO:0050886|endocrine process, ! myoblast differentiation GO:0045445 31 18 0,000 0,01617336 0,02781115 ! inactivation of MAPK activity GO:0000188 28 18 0,000 0,01617336 0,02779102 ! negative regulation of epithelial cell proliferation GO:0050680 36 18 0,000 0,01617336 0,02777091 ! vacuolar transport GO:0007034 26 18 0,000 0,01617336 0,02775083 ! pigmentation during development GO:0048066 35 18 0,000 0,01617336 0,02773078 ! cell-substrate junction assembly GO:0007044 45 18 0,000 0,01617336 0,02771075 ! cellular macromolecular complex disassembly GO:0034623 30 18 0,000 0,01617336 0,02769076 ! cellular response to unfolded protein GO:0034620 24 18 0,000 0,01617336 0,0276708 GO:0030968|endoplasmic reticulum unfolded protein response, ! fucose metabolic process GO:0006004 27 18 0,000 0,01617336 0,02765086 ! actin filament bundle formation GO:0051017 30 18 0,000 0,01617336 0,02763095 ! body fluid secretion GO:0007589 27 18 0,000 0,01617336 0,02761107 ! regulation of dephosphorylation GO:0035303 38 18 0,000 0,01617336 0,02759122 ! NLS-bearing substrate import into nucleus GO:0006607 40 18 0,000 0,01617336 0,0275714 ! behavioral interaction between organisms GO:0051705 26 18 0,000 0,01617336 0,02755161 ! negative regulation of immune response GO:0050777 33 18 0,000 0,01617336 0,02753185 ! heart process GO:0003015 32 18 0,000 0,01617336 0,02751211 GO:0060047|heart contraction, ! regulation of T cell mediated immunity GO:0002709 39 18 0,000 0,01617336 0,0274924 ! sensory perception of pain GO:0019233 26 18 0,000 0,01617336 0,02747272 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 18 0,000 0,01617336 0,02745307 ! ribosomal small subunit biogenesis GO:0042274 22 18 0,000 0,01617336 0,02743345 ! somitogenesis GO:0001756 25 18 0,000 0,01617336 0,02741385 ! neural crest cell migration GO:0001755 28 18 0,000 0,01617336 0,02739429 ! neutrophil chemotaxis GO:0030593 26 18 0,000 0,01617336 0,02737475 ! positive regulation of intracellular transport GO:0032388 30 18 0,000 0,01617336 0,02735523 ! negative regulation of intracellular transport GO:0032387 31 18 0,000 0,01617336 0,02733575 ! synaptogenesis GO:0007416 28 18 0,000 0,01617336 0,02731629 ! cell-cell junction organization GO:0045216 28 18 0,000 0,01617336 0,02729687 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,01617336 0,02727747 ! purine nucleotide catabolic process GO:0006195 27 18 0,000 0,01617336 0,02725809 ! proximal/distal pattern formation GO:0009954 28 18 0,000 0,01617336 0,02723875 ! regulation of generation of precursor metabolites and energy GO:0043467 29 18 0,000 0,01617336 0,02721943 ! aromatic compound catabolic process GO:0019439 26 18 0,000 0,01617336 0,02720014 ! somatic recombination of immunoglobulin gene segments GO:0016447 28 18 0,000 0,01617336 0,02718087 ! gut development GO:0048565 29 18 0,000 0,01617336 0,02716164 ! negative regulation of leukocyte proliferation GO:0070664 35 18 0,000 0,01617336 0,02714243 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! antigen receptor-mediated signaling pathway GO:0050851 33 18 0,000 0,01617336 0,02712325 ! positive regulation of synaptic transmission GO:0050806 26 18 0,000 0,01617336 0,02710409 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 28 19 0,000 0,0170646 0,02857749 ! positive regulation of translation GO:0045727 29 19 0,000 0,0170646 0,02855733 ! positive regulation of cell size GO:0045793 26 19 0,000 0,0170646 0,02853721 ! phosphatidylinositol metabolic process GO:0046488 24 19 0,000 0,0170646 0,02851711 ! glycerol metabolic process GO:0006071 22 19 0,000 0,0170646 0,02849704 ! phosphoinositide phosphorylation GO:0046854 26 19 0,000 0,0170646 0,028477 ! regulation of neuronal synaptic plasticity GO:0048168 37 19 0,000 0,0170646 0,02845699 ! endothelial cell migration GO:0043542 24 19 0,000 0,0170646 0,02843701 ! glycosaminoglycan biosynthetic process GO:0006024 27 19 0,000 0,0170646 0,02841705 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 23 19 0,000 0,0170646 0,02839712 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 19 0,000 0,0170646 0,02837722 ! memory GO:0007613 28 19 0,000 0,0170646 0,02835735 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 19 0,000 0,0170646 0,02833751 ! pancreas development GO:0031016 27 19 0,000 0,0170646 0,02831769 ! response to carbohydrate stimulus GO:0009743 28 19 0,000 0,0170646 0,0282979 ! DNA duplex unwinding GO:0032508 28 19 0,000 0,0170646 0,02827814 GO:0032392|DNA geometric change, ! peroxisome organization GO:0007031 30 19 0,000 0,0170646 0,02825841 ! central nervous system neuron development GO:0021954 33 19 0,000 0,0170646 0,0282387 ! polysaccharide catabolic process GO:0000272 24 19 0,000 0,0170646 0,02821902 ! actin polymerization or depolymerization GO:0008154 32 19 0,000 0,0170646 0,02819937 ! vesicle docking during exocytosis GO:0006904 25 19 0,000 0,0170646 0,02817975 ! heme metabolic process GO:0042168 29 19 0,000 0,0170646 0,02816015 ! negative regulation of protein catabolic process GO:0042177 29 19 0,000 0,0170646 0,02814058 ! response to lipopolysaccharide GO:0032496 28 19 0,000 0,0170646 0,02812104 ! response to fungus GO:0009620 21 19 0,000 0,0170646 0,02810153 ! peptide cross-linking GO:0018149 35 19 0,000 0,0170646 0,02808204 ! ventricular cardiac muscle morphogenesis GO:0055010 25 19 0,000 0,0170646 0,02806258 ! determination of left/right symmetry GO:0007368 24 19 0,000 0,0170646 0,02804314 ! prostaglandin metabolic process GO:0006693 34 19 0,000 0,0170646 0,02802374 GO:0006692|prostanoid metabolic process, ! regulation of immunoglobulin mediated immune response GO:0002889 29 19 0,000 0,0170646 0,02800436 GO:0002712|regulation of B cell mediated immunity, ! detection of chemical stimulus GO:0009593 28 19 0,000 0,0170646 0,027985 ! vitamin transport GO:0051180 26 19 0,000 0,0170646 0,02796568 ! sarcomere organization GO:0045214 26 19 0,000 0,0170646 0,02794638 ! positive regulation of myeloid cell differentiation GO:0045639 50 19 0,000 0,0170646 0,0279271 ! regulation of immunoglobulin production GO:0002637 29 19 0,000 0,0170646 0,02790786 ! positive regulation of transmission of nerve impulse GO:0051971 27 19 0,000 0,0170646 0,02788864 ! leukotriene biosynthetic process GO:0019370 27 19 0,000 0,0170646 0,02786944 GO:0043450|alkene biosynthetic process, ! regulation of glucose import GO:0046324 23 19 0,000 0,0170646 0,02785027 GO:0010827|regulation of glucose transport, ! negative regulation of coagulation GO:0050819 25 19 0,000 0,0170646 0,02783113 ! oligosaccharide metabolic process GO:0009311 35 20 0,000 0,01795508 0,02926332 ! positive regulation of angiogenesis GO:0045766 42 20 0,000 0,01795508 0,02924324 ! determination of bilateral symmetry GO:0009855 26 20 0,000 0,01795508 0,02922318 GO:0009799|determination of symmetry, ! N-acetylglucosamine metabolic process GO:0006044 25 20 0,000 0,01795508 0,02920315 ! lipid phosphorylation GO:0046834 28 20 0,000 0,01795508 0,02918315 ! aminoglycan biosynthetic process GO:0006023 28 20 0,000 0,01795508 0,02916317 ! hindlimb morphogenesis GO:0035137 35 20 0,000 0,01795508 0,02914323 ! C21-steroid hormone metabolic process GO:0008207 25 20 0,000 0,01795508 0,0291233 ! calcium-independent cell-cell adhesion GO:0016338 23 20 0,000 0,01795508 0,02910341 ! response to alkaloid GO:0043279 34 20 0,000 0,01795508 0,02908355 ! sensory perception of taste GO:0050909 26 20 0,000 0,01795508 0,02906371 ! response to retinoic acid GO:0032526 27 20 0,000 0,01795508 0,0290439 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 20 0,000 0,01795508 0,02902411 ! cellular response to reactive oxygen species GO:0034614 32 20 0,000 0,01795508 0,02900435 ! D-ribose metabolic process GO:0006014 27 20 0,000 0,01795508 0,02898462 ! chromosome condensation GO:0030261 32 20 0,000 0,01795508 0,02896492 ! peptidyl-serine phosphorylation GO:0018105 31 20 0,000 0,01795508 0,02894524 ! sex determination GO:0007530 32 20 0,000 0,01795508 0,02892559 ! plasma membrane fusion GO:0045026 24 20 0,000 0,01795508 0,02890597 ! fatty acid beta-oxidation GO:0006635 32 20 0,000 0,01795508 0,02888637 ! positive regulation of alpha-beta T cell differentiation GO:0046638 29 20 0,000 0,01795508 0,0288668 ! cytolysis GO:0019835 21 20 0,000 0,01795508 0,02884725 ! renal system process GO:0003014 35 20 0,000 0,01795508 0,02882774 ! vasodilation GO:0042311 36 20 0,000 0,01795508 0,02880825 ! negative regulation of angiogenesis GO:0016525 38 20 0,000 0,01795508 0,02878878 ! detection of biotic stimulus GO:0009595 23 20 0,000 0,01795508 0,02876934 ! cellular response to nutrient levels GO:0031669 32 20 0,000 0,01795508 0,02874993 ! positive regulation of neurological system process GO:0031646 31 20 0,000 0,01795508 0,02873054 ! hormone transport GO:0009914 30 20 0,000 0,01795508 0,02871118 ! negative regulation of neuron differentiation GO:0045665 33 20 0,000 0,01795508 0,02869185 ! activation of JUN kinase activity GO:0007257 28 20 0,000 0,01795508 0,02867254 ! regulation of leukocyte mediated cytotoxicity GO:0001910 34 20 0,000 0,01795508 0,02865326 ! estrogen receptor signaling pathway GO:0030520 36 20 0,000 0,01795508 0,028634 ! sperm-egg recognition GO:0035036 24 20 0,000 0,01795508 0,02861477 GO:0007339|binding of sperm to zona pellucida, ! embryonic organ morphogenesis GO:0048562 26 20 0,000 0,01795508 0,02859557 ! negative regulation of translation GO:0017148 28 20 0,000 0,01795508 0,02857639 ! cellular monovalent inorganic cation homeostasis GO:0030004 31 20 0,000 0,01795508 0,02855724 ! positive regulation of DNA replication GO:0045740 37 21 0,000 0,01884479 0,02995223 ! positive regulation of protein catabolic process GO:0045732 25 21 0,000 0,01884479 0,02993218 ! positive regulation of fibroblast proliferation GO:0048146 30 21 0,000 0,01884479 0,02991216 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,01884479 0,02989217 ! positive regulation of ossification GO:0045778 34 21 0,000 0,01884479 0,0298722 ! G2/M transition of mitotic cell cycle GO:0000086 34 21 0,000 0,01884479 0,02985226 ! iron ion transport GO:0006826 49 21 0,000 0,01884479 0,02983234 ! glucosamine metabolic process GO:0006041 26 21 0,000 0,01884479 0,02981246 ! microtubule-based transport GO:0010970 41 21 0,000 0,01884479 0,02979259 ! vesicle docking GO:0048278 28 21 0,000 0,01884479 0,02977276 ! regulation of carbohydrate metabolic process GO:0006109 31 21 0,000 0,01884479 0,02975295 GO:0010675|regulation of cellular carbohydrate metabolic process, ! ovarian follicle development GO:0001541 33 21 0,000 0,01884479 0,02973317 ! apoptotic mitochondrial changes GO:0008637 42 21 0,000 0,01884479 0,02971341 ! response to ethanol GO:0045471 38 21 0,000 0,01884479 0,02969368 ! positive regulation of epithelial cell proliferation GO:0050679 43 21 0,000 0,01884479 0,02967398 ! smooth muscle contraction GO:0006939 39 21 0,000 0,01884479 0,0296543 ! glutamine metabolic process GO:0006541 29 21 0,000 0,01884479 0,02963465 ! response to vitamin A GO:0033189 28 21 0,000 0,01884479 0,02961502 ! purine ribonucleoside metabolic process GO:0046128 30 21 0,000 0,01884479 0,02959542 GO:0042278|purine nucleoside metabolic process, ! neurotransmitter metabolic process GO:0042133 36 21 0,000 0,01884479 0,02957585 ! response to starvation GO:0042594 35 21 0,000 0,01884479 0,0295563 ! regulation of myeloid leukocyte differentiation GO:0002761 41 21 0,000 0,01884479 0,02953678 ! leukotriene metabolic process GO:0006691 29 21 0,000 0,01884479 0,02951728 ! regulation of vasoconstriction GO:0019229 33 21 0,000 0,01884479 0,02949781 ! glycosphingolipid metabolic process GO:0006687 35 21 0,000 0,01884479 0,02947837 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 28 21 0,000 0,01884479 0,02945895 ! regulation of fatty acid metabolic process GO:0019217 32 21 0,000 0,01884479 0,02943955 ! visual learning GO:0008542 38 21 0,000 0,01884479 0,02942019 ! negative regulation of Wnt receptor signaling pathway GO:0030178 32 21 0,000 0,01884479 0,02940084 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 38 21 0,000 0,01884479 0,02938153 ! positive regulation of inflammatory response GO:0050729 38 21 0,000 0,01884479 0,02936223 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,01884479 0,02934297 ! neuromuscular process controlling balance GO:0050885 54 21 0,000 0,01884479 0,02932373 ! negative regulation of myeloid cell differentiation GO:0045638 29 21 0,000 0,01884479 0,02930451 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,01884479 0,02928532 ! aromatic amino acid family metabolic process GO:0009072 30 21 0,000 0,01884479 0,02926615 ! somatic diversification of immunoglobulins GO:0016445 31 21 0,000 0,01884479 0,02924701 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,01884479 0,0292279 ! negative regulation of T cell activation GO:0050868 35 21 0,000 0,01884479 0,02920881 ! regulation of microtubule polymerization or depolymerization GO:0031110 51 21 0,000 0,01884479 0,02918974 ! embryonic pattern specification GO:0009880 34 22 0,000 0,01973374 0,03054675 ! regulation of cell killing GO:0031341 37 22 0,000 0,01973374 0,03052683 ! regulation of anti-apoptosis GO:0045767 40 22 0,000 0,01973374 0,03050695 ! gluconeogenesis GO:0006094 26 22 0,000 0,01973374 0,03048709 ! viral genome replication GO:0019079 31 22 0,000 0,01973374 0,03046725 ! nucleotide-excision repair, DNA damage removal GO:0000718 27 22 0,000 0,01973374 0,03044744 ! protein amino acid O-linked glycosylation GO:0006493 36 22 0,000 0,01973374 0,03042766 ! protein amino acid acylation GO:0043543 42 22 0,000 0,01973374 0,0304079 ! response to vitamin GO:0033273 31 22 0,000 0,01973374 0,03038817 ! molting cycle process GO:0022404 43 22 0,000 0,01973374 0,03036846 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of neurotransmitter transport GO:0051588 41 22 0,000 0,01973374 0,03034878 ! regeneration GO:0031099 37 22 0,000 0,01973374 0,03032912 ! phototransduction GO:0007602 29 22 0,000 0,01973374 0,03030949 ! regulation of DNA recombination GO:0000018 43 22 0,000 0,01973374 0,03028989 ! regulation of smooth muscle contraction GO:0006940 38 22 0,000 0,01973374 0,03027031 ! deoxyribonucleotide metabolic process GO:0009262 29 22 0,000 0,01973374 0,03025075 ! central nervous system neuron differentiation GO:0021953 39 22 0,000 0,01973374 0,03023122 ! cholesterol biosynthetic process GO:0006695 32 22 0,000 0,01973374 0,03021172 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 22 0,000 0,01973374 0,03019224 ! regulation of interleukin-6 production GO:0032675 25 22 0,000 0,01973374 0,03017279 ! regulation of interleukin-2 production GO:0032663 38 22 0,000 0,01973374 0,03015336 ! pallium development GO:0021543 43 22 0,000 0,01973374 0,03013395 ! positive regulation of locomotion GO:0040017 40 22 0,000 0,01973374 0,03011458 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! fatty acid transport GO:0015908 33 22 0,000 0,01973374 0,03009522 ! platelet activation GO:0030168 33 22 0,000 0,01973374 0,03007589 ! proteoglycan biosynthetic process GO:0030166 33 22 0,000 0,01973374 0,03005659 ! regulation of cytokine secretion GO:0050707 30 22 0,000 0,01973374 0,03003731 ! positive regulation of osteoblast differentiation GO:0045669 37 22 0,000 0,01973374 0,03001805 ! cellular alkene metabolic process GO:0043449 30 22 0,000 0,01973374 0,02999882 ! cell-cell recognition GO:0009988 28 22 0,000 0,01973374 0,02997962 ! pyrimidine nucleoside metabolic process GO:0006213 28 22 0,000 0,01973374 0,02996044 ! water-soluble vitamin biosynthetic process GO:0042364 28 22 0,000 0,01973374 0,02994128 ! neural tube closure GO:0001843 35 22 0,000 0,01973374 0,02992215 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 26 22 0,000 0,01973374 0,02990304 ! regulation of multi-organism process GO:0043900 35 22 0,000 0,01973374 0,02988396 ! protein tetramerization GO:0051262 43 22 0,000 0,01973374 0,0298649 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 36 23 0,000 0,02062193 0,03118919 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid metabolic process GO:0000096 31 23 0,000 0,02062193 0,03116933 ! reciprocal meiotic recombination GO:0007131 41 23 0,000 0,02062193 0,03114948 ! cellular aldehyde metabolic process GO:0006081 32 23 0,000 0,02062193 0,03112967 ! positive regulation of bone remodeling GO:0046852 37 23 0,000 0,02062193 0,03110988 ! cellular polysaccharide biosynthetic process GO:0033692 29 23 0,000 0,02062193 0,03109011 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 31 23 0,000 0,02062193 0,03107037 ! dicarboxylic acid metabolic process GO:0043648 36 23 0,000 0,02062193 0,03105066 ! regulation of chemotaxis GO:0050920 41 23 0,000 0,02062193 0,03103097 ! regulation of receptor-mediated endocytosis GO:0048259 26 23 0,000 0,02062193 0,03101131 ! tube lumen formation GO:0035148 37 23 0,000 0,02062193 0,03099167 ! macromolecular complex disassembly GO:0032984 39 23 0,000 0,02062193 0,03097205 ! dendrite development GO:0016358 41 23 0,000 0,02062193 0,03095246 ! vasculogenesis GO:0001570 38 23 0,000 0,02062193 0,0309329 ! microtubule organizing center organization GO:0031023 30 23 0,000 0,02062193 0,03091335 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 50 23 0,000 0,02062193 0,03089384 ! lysosome organization GO:0007040 41 23 0,000 0,02062193 0,03087435 ! digestive system process GO:0022600 35 23 0,000 0,02062193 0,03085488 ! positive regulation of cytoskeleton organization GO:0051495 43 23 0,000 0,02062193 0,03083544 ! vesicle targeting GO:0006903 35 23 0,000 0,02062193 0,03081602 ! response to corticosteroid stimulus GO:0031960 37 23 0,000 0,02062193 0,03079663 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 36 23 0,000 0,02062193 0,03077726 ! regulation of endothelial cell migration GO:0010594 44 23 0,000 0,02062193 0,03075791 ! regulation of viral reproduction GO:0050792 33 23 0,000 0,02062193 0,03073859 ! regulation of insulin secretion GO:0050796 30 23 0,000 0,02062193 0,0307193 ! regulation of alpha-beta T cell differentiation GO:0046637 35 23 0,000 0,02062193 0,03070003 ! cardiac muscle tissue morphogenesis GO:0055008 29 23 0,000 0,02062193 0,03068078 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 42 23 0,000 0,02062193 0,03066155 ! membrane depolarization GO:0051899 40 23 0,000 0,02062193 0,03064235 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,02062193 0,03062318 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 39 23 0,000 0,02062193 0,03060403 ! regulation of ARF GTPase activity GO:0032312 35 23 0,000 0,02062193 0,0305849 ! DNA modification GO:0006304 33 23 0,000 0,02062193 0,0305658 ! collagen fibril organization GO:0030199 50 23 0,000 0,02062193 0,03054672 ! synaptic vesicle transport GO:0048489 45 23 0,000 0,02062193 0,03052766 ! cellular response to extracellular stimulus GO:0031668 37 23 0,000 0,02062193 0,03050863 ! peptidyl-serine modification GO:0018209 37 23 0,000 0,02062193 0,03048962 ! nerve-nerve synaptic transmission GO:0007270 42 23 0,000 0,02062193 0,03047064 ! fat-soluble vitamin metabolic process GO:0006775 29 23 0,000 0,02062193 0,03045167 ! positive regulation of B cell activation GO:0050871 36 23 0,000 0,02062193 0,03043274 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,02062193 0,03041382 ! collagen catabolic process GO:0030574 29 23 0,000 0,02062193 0,03039493 ! glutamine family amino acid catabolic process GO:0009065 34 23 0,000 0,02062193 0,03037606 ! aspartate family amino acid metabolic process GO:0009066 27 23 0,000 0,02062193 0,03035722 ! porphyrin metabolic process GO:0006778 37 23 0,000 0,02062193 0,0303384 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 39 23 0,000 0,02062193 0,0303196 ! blastocyst development GO:0001824 41 23 0,000 0,02062193 0,03030083 ! actin filament-based movement GO:0030048 37 23 0,000 0,02062193 0,03028208 ! protein stabilization GO:0050821 34 23 0,000 0,02062193 0,03026335 ! protein import into nucleus, docking GO:0000059 45 24 0,000 0,02150936 0,03154618 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 30 24 0,000 0,02150936 0,03152669 ! myelination GO:0042552 39 24 0,000 0,02150936 0,03150723 ! initiation of viral infection GO:0019059 47 24 0,000 0,02150936 0,03148779 ! regulation of transmembrane transport GO:0034762 31 24 0,000 0,02150936 0,03146838 ! leukocyte adhesion GO:0007159 49 24 0,000 0,02150936 0,03144899 ! glutamate signaling pathway GO:0007215 37 24 0,000 0,02150936 0,03142963 ! regulation of transcription factor import into nucleus GO:0042990 49 24 0,000 0,02150936 0,03141028 ! visual behavior GO:0007632 42 24 0,000 0,02150936 0,03139097 ! spinal cord development GO:0021510 41 24 0,000 0,02150936 0,03137167 ! immune response-activating cell surface receptor signaling pathway GO:0002429 39 24 0,000 0,02150936 0,0313524 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 46 24 0,000 0,02150936 0,03133316 ! multicellular organismal response to stress GO:0033555 42 24 0,000 0,02150936 0,03131393 ! regulation of nitric oxide biosynthetic process GO:0045428 42 24 0,000 0,02150936 0,03129473 ! negative regulation of DNA replication GO:0008156 39 24 0,000 0,02150936 0,03127556 ! cell aging GO:0007569 38 24 0,000 0,02150936 0,03125641 ! osteoblast differentiation GO:0001649 43 24 0,000 0,02150936 0,03123728 ! response to endoplasmic reticulum stress GO:0034976 32 24 0,000 0,02150936 0,03121817 ! response to toxin GO:0009636 38 24 0,000 0,02150936 0,03119909 ! primary neural tube formation GO:0014020 37 24 0,000 0,02150936 0,03118003 ! vitamin biosynthetic process GO:0009110 30 24 0,000 0,02150936 0,031161 ! positive regulation of alpha-beta T cell activation GO:0046635 40 24 0,000 0,02150936 0,03114198 ! cellular response to oxidative stress GO:0034599 38 24 0,000 0,02150936 0,031123 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 24 0,000 0,02150936 0,03110403 ! fibroblast growth factor receptor signaling pathway GO:0008543 45 24 0,000 0,02150936 0,03108509 ! pentose metabolic process GO:0019321 33 24 0,000 0,02150936 0,03106617 ! immunoglobulin production GO:0002377 37 24 0,000 0,02150936 0,03104727 GO:0002440|production of molecular mediator of immune response, ! regulation of response to biotic stimulus GO:0002831 45 24 0,000 0,02150936 0,0310284 ! positive regulation of protein secretion GO:0050714 29 24 0,000 0,02150936 0,03100955 ! positive regulation of adaptive immune response GO:0002821 44 24 0,000 0,02150936 0,03099072 ! regulation of blood coagulation GO:0030193 37 24 0,000 0,02150936 0,03097191 ! positive regulation of tissue remodeling GO:0034105 41 24 0,000 0,02150936 0,03095313 ! group transfer coenzyme metabolic process GO:0006752 29 24 0,000 0,02150936 0,03093437 ! response to molecule of bacterial origin GO:0002237 38 24 0,000 0,02150936 0,03091563 ! positive regulation of JUN kinase activity GO:0043507 33 24 0,000 0,02150936 0,03089692 ! regulation of fibroblast proliferation GO:0048145 39 25 0,000 0,02239603 0,03215111 ! neuron fate commitment GO:0048663 38 25 0,000 0,02239603 0,03213167 ! pyruvate metabolic process GO:0006090 32 25 0,000 0,02239603 0,03211226 ! superoxide metabolic process GO:0006801 33 25 0,000 0,02239603 0,03209286 ! detection of light stimulus involved in sensory perception GO:0050962 32 25 0,000 0,02239603 0,0320735 GO:0050908|detection of light stimulus involved in visual perception, ! regulation of cell-matrix adhesion GO:0001952 57 25 0,000 0,02239603 0,03205415 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 44 25 0,000 0,02239603 0,03203483 ! mitochondrial membrane organization GO:0007006 42 25 0,000 0,02239603 0,03201553 ! vacuole organization GO:0007033 43 25 0,000 0,02239603 0,03199626 ! receptor metabolic process GO:0043112 40 25 0,000 0,02239603 0,03197701 ! barbed-end actin filament capping GO:0051016 41 25 0,000 0,02239603 0,03195778 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 35 25 0,000 0,02239603 0,03193857 ! regulation of behavior GO:0050795 45 25 0,000 0,02239603 0,03191939 ! hydrogen peroxide metabolic process GO:0042743 35 25 0,000 0,02239603 0,03190023 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 45 25 0,000 0,02239603 0,03188109 ! lymphocyte proliferation GO:0046651 42 25 0,000 0,02239603 0,03186198 ! negative regulation of phosphorylation GO:0042326 46 25 0,000 0,02239603 0,03184289 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,02239603 0,03182382 ! regulation of tumor necrosis factor production GO:0032680 32 25 0,000 0,02239603 0,03180478 ! leukocyte homeostasis GO:0001776 40 25 0,000 0,02239603 0,03178576 ! positive regulation of nuclear division GO:0051785 41 25 0,000 0,02239603 0,03176676 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 38 25 0,000 0,02239603 0,03174778 ! camera-type eye morphogenesis GO:0048593 43 25 0,000 0,02239603 0,03172883 ! negative regulation of catabolic process GO:0009895 37 25 0,000 0,02239603 0,03170989 ! regulation of amine transport GO:0051952 44 25 0,000 0,02239603 0,03169099 ! liver development GO:0001889 44 25 0,000 0,02239603 0,0316721 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 38 26 0,000 0,02328194 0,03290533 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 31 26 0,000 0,02328194 0,03288575 ! positive regulation of cell projection organization GO:0031346 43 26 0,000 0,02328194 0,03286618 ! regulation of cellular catabolic process GO:0031329 39 26 0,000 0,02328194 0,03284664 ! regulation of interferon-gamma production GO:0032649 33 26 0,000 0,02328194 0,03282713 ! cellular iron ion homeostasis GO:0006879 47 26 0,000 0,02328194 0,03280763 ! epidermal growth factor receptor signaling pathway GO:0007173 42 26 0,000 0,02328194 0,03278816 ! amino sugar metabolic process GO:0006040 32 26 0,000 0,02328194 0,03276871 ! protein amino acid alkylation GO:0008213 40 26 0,000 0,02328194 0,03274929 GO:0006479|protein amino acid methylation, ! odontogenesis of dentine-containing tooth GO:0042475 43 26 0,000 0,02328194 0,03272989 ! insulin receptor signaling pathway GO:0008286 48 26 0,000 0,02328194 0,03271051 ! sperm motility GO:0030317 31 26 0,000 0,02328194 0,03269116 ! ER-nuclear signaling pathway GO:0006984 33 26 0,000 0,02328194 0,03267182 ! peptidyl-tyrosine phosphorylation GO:0018108 42 26 0,000 0,02328194 0,03265251 ! male gonad development GO:0008584 39 26 0,000 0,02328194 0,03263323 ! neural crest cell development GO:0014032 44 26 0,000 0,02328194 0,03261396 GO:0014033|neural crest cell differentiation, ! base-excision repair GO:0006284 35 26 0,000 0,02328194 0,03259472 ! cell fate determination GO:0001709 54 26 0,000 0,02328194 0,0325755 ! regulation of chromosome organization GO:0033044 37 26 0,000 0,02328194 0,03255631 ! regulation of oxidoreductase activity GO:0051341 42 26 0,000 0,02328194 0,03253713 ! detection of visible light GO:0009584 33 26 0,000 0,02328194 0,03251798 ! spermatid development GO:0007286 40 26 0,000 0,02328194 0,03249885 ! regulation of bone mineralization GO:0030500 38 26 0,000 0,02328194 0,03247975 ! regulation of osteoblast differentiation GO:0045667 41 26 0,000 0,02328194 0,03246067 ! acetyl-CoA catabolic process GO:0046356 38 26 0,000 0,02328194 0,0324416 GO:0006099|tricarboxylic acid cycle, ! regulation of JUN kinase activity GO:0043506 39 26 0,000 0,02328194 0,03242257 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,0241671 0,0336355 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 47 27 0,000 0,0241671 0,03361578 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 42 27 0,000 0,0241671 0,03359609 ! membrane docking GO:0022406 40 27 0,000 0,0241671 0,03357642 ! circadian rhythm GO:0007623 44 27 0,000 0,0241671 0,03355677 ! regulation of endothelial cell proliferation GO:0001936 52 27 0,000 0,0241671 0,03353715 ! fat cell differentiation GO:0045444 41 27 0,000 0,0241671 0,03351755 ! positive regulation of innate immune response GO:0045089 34 27 0,000 0,0241671 0,03349797 ! autophagy GO:0006914 36 27 0,000 0,0241671 0,03347841 ! myofibril assembly GO:0030239 40 27 0,000 0,0241671 0,03345888 GO:0055002|striated muscle cell development, ! negative regulation of phosphorus metabolic process GO:0010563 51 27 0,000 0,0241671 0,03343937 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 38 27 0,000 0,0241671 0,03341988 ! peptide transport GO:0015833 46 27 0,000 0,0241671 0,03340042 ! coenzyme catabolic process GO:0009109 40 27 0,000 0,0241671 0,03338098 ! regulation of peptide secretion GO:0002791 39 27 0,000 0,0241671 0,03336156 ! negative regulation of cell development GO:0010721 67 27 0,000 0,0241671 0,03334216 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 46 27 0,000 0,0241671 0,03332279 ! positive regulation of leukocyte mediated immunity GO:0002705 45 27 0,000 0,0241671 0,03330344 GO:0002708|positive regulation of lymphocyte mediated immunity, ! phospholipid transport GO:0015914 40 27 0,000 0,0241671 0,03328411 ! detection of light stimulus GO:0009583 35 27 0,000 0,0241671 0,0332648 ! glutathione metabolic process GO:0006749 35 27 0,000 0,0241671 0,03324552 ! lipid oxidation GO:0034440 39 27 0,000 0,0241671 0,03322626 GO:0019395|fatty acid oxidation, ! leukocyte proliferation GO:0070661 45 27 0,000 0,0241671 0,03320702 GO:0032943|mononuclear cell proliferation, ! telomere organization GO:0032200 39 27 0,000 0,0241671 0,0331878 GO:0000723|telomere maintenance, ! negative regulation of neuron apoptosis GO:0043524 48 27 0,000 0,0241671 0,03316861 ! protein import into nucleus, translocation GO:0000060 47 28 0,000 0,02505149 0,03436254 ! positive regulation of smooth muscle cell proliferation GO:0048661 45 28 0,000 0,02505149 0,03434269 ! translational initiation GO:0006413 48 28 0,000 0,02505149 0,03432286 ! negative regulation of actin filament depolymerization GO:0030835 44 28 0,000 0,02505149 0,03430306 ! acetyl-CoA metabolic process GO:0006084 42 28 0,000 0,02505149 0,03428327 ! regulation of pH GO:0006885 40 28 0,000 0,02505149 0,03426351 ! negative regulation of protein modification process GO:0031400 56 28 0,000 0,02505149 0,03424378 ! catechol metabolic process GO:0009712 46 28 0,000 0,02505149 0,03422406 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 43 28 0,000 0,02505149 0,03420437 ! cellular carbohydrate biosynthetic process GO:0034637 37 28 0,000 0,02505149 0,0341847 ! iron ion homeostasis GO:0055072 49 28 0,000 0,02505149 0,03416505 ! regulation of biomineral formation GO:0070167 40 28 0,000 0,02505149 0,03414543 ! peptidyl-tyrosine modification GO:0018212 44 28 0,000 0,02505149 0,03412583 ! neurotransmitter secretion GO:0007269 41 28 0,000 0,02505149 0,03410625 ! negative regulation of transcription regulator activity GO:0090048 48 28 0,000 0,02505149 0,03408669 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of lymphocyte activation GO:0051250 48 28 0,000 0,02505149 0,03406716 ! gene silencing GO:0016458 47 28 0,000 0,02505149 0,03404765 ! regulation of coagulation GO:0050818 42 28 0,000 0,02505149 0,03402816 ! negative regulation of actin filament polymerization GO:0030837 45 29 0,000 0,02593513 0,03520828 ! phenol metabolic process GO:0018958 47 29 0,000 0,02593513 0,03518815 ! positive regulation of cell adhesion GO:0045785 54 29 0,000 0,02593513 0,03516804 ! icosanoid biosynthetic process GO:0046456 45 29 0,000 0,02593513 0,03514796 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 39 29 0,000 0,02593513 0,03512789 ! calcium-dependent cell-cell adhesion GO:0016339 36 29 0,000 0,02593513 0,03510786 ! negative regulation of response to external stimulus GO:0032102 39 29 0,000 0,02593513 0,03508784 ! cholesterol transport GO:0030301 48 29 0,000 0,02593513 0,03506785 GO:0015918|sterol transport, ! cholesterol homeostasis GO:0042632 53 29 0,000 0,02593513 0,03504788 GO:0055092|sterol homeostasis, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 39 29 0,000 0,02593513 0,03502793 ! GPI anchor metabolic process GO:0006505 47 29 0,000 0,02593513 0,035008 ! complement activation, classical pathway GO:0006958 39 29 0,000 0,02593513 0,0349881 ! multicellular organismal catabolic process GO:0044243 36 29 0,000 0,02593513 0,03496822 ! respiratory gaseous exchange GO:0007585 51 29 0,000 0,02593513 0,03494836 ! triglyceride metabolic process GO:0006641 38 29 0,000 0,02593513 0,03492853 ! response to ionizing radiation GO:0010212 55 29 0,000 0,02593513 0,03490872 ! muscle cell development GO:0055001 42 29 0,000 0,02593513 0,03488893 ! response to organic cyclic substance GO:0014070 53 29 0,000 0,02593513 0,03486916 ! regulation of systemic arterial blood pressure GO:0003073 52 29 0,000 0,02593513 0,03484942 ! mesoderm formation GO:0001707 52 29 0,000 0,02593513 0,03482969 ! response to estradiol stimulus GO:0032355 38 29 0,000 0,02593513 0,03480999 ! positive regulation of MAPKKK cascade GO:0043410 45 29 0,000 0,02593513 0,03479032 ! regulation of microtubule cytoskeleton organization GO:0070507 61 29 0,000 0,02593513 0,03477066 ! ensheathment of neurons GO:0007272 48 29 0,000 0,02593513 0,03475103 GO:0008366|axon ensheathment, ! serine family amino acid metabolic process GO:0009069 41 29 0,000 0,02593513 0,03473142 ! spermatid differentiation GO:0048515 45 29 0,000 0,02593513 0,03471183 ! myeloid leukocyte activation GO:0002274 44 29 0,000 0,02593513 0,03469226 ! neural tube formation GO:0001841 46 29 0,000 0,02593513 0,03467272 ! regulation of actin filament depolymerization GO:0030834 47 30 0,000 0,02681802 0,03583286 ! organic anion transport GO:0015711 50 30 0,000 0,02681802 0,03581269 ! cell junction assembly GO:0034329 65 30 0,000 0,02681802 0,03579255 ! acute-phase response GO:0006953 49 30 0,000 0,02681802 0,03577243 ! segmentation GO:0035282 43 30 0,000 0,02681802 0,03575233 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 56 30 0,000 0,02681802 0,03573226 ! negative regulation of protein kinase cascade GO:0010741 58 30 0,000 0,02681802 0,03571221 ! immune response-activating signal transduction GO:0002757 45 30 0,000 0,02681802 0,03569218 ! regulation of protein import into nucleus GO:0042306 56 30 0,000 0,02681802 0,03567217 ! regulation of production of molecular mediator of immune response GO:0002700 47 30 0,000 0,02681802 0,03565219 ! ceramide metabolic process GO:0006672 47 30 0,000 0,02681802 0,03563222 ! formation of primary germ layer GO:0001704 54 30 0,000 0,02681802 0,03561228 ! nicotinamide metabolic process GO:0006769 47 30 0,000 0,02681802 0,03559237 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 50 30 0,000 0,02681802 0,03557247 ! fatty acid catabolic process GO:0009062 45 30 0,000 0,02681802 0,0355526 ! regulation of calcium ion transport GO:0051924 40 30 0,000 0,02681802 0,03553275 ! negative regulation of protein polymerization GO:0032272 47 30 0,000 0,02681802 0,03551292 ! negative regulation of protein transport GO:0051224 53 30 0,000 0,02681802 0,03549311 ! establishment of vesicle localization GO:0051650 48 30 0,000 0,02681802 0,03547333 ! alkaloid metabolic process GO:0009820 48 31 0,000 0,02770014 0,03661974 ! response to hydrogen peroxide GO:0042542 48 31 0,000 0,02770014 0,03659935 ! post-embryonic development GO:0009791 50 31 0,000 0,02770014 0,03657899 ! inner ear morphogenesis GO:0042472 43 31 0,000 0,02770014 0,03655864 ! regulation of innate immune response GO:0045088 42 31 0,000 0,02770014 0,03653832 ! ovulation cycle process GO:0022602 46 31 0,000 0,02770014 0,03651802 ! mesoderm morphogenesis GO:0048332 54 31 0,000 0,02770014 0,03649774 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 42 31 0,000 0,02770014 0,03647749 ! immune response-regulating signal transduction GO:0002764 51 31 0,000 0,02770014 0,03645726 ! positive regulation of neurogenesis GO:0050769 49 31 0,000 0,02770014 0,03643705 ! positive regulation of T cell differentiation GO:0045582 45 31 0,000 0,02770014 0,03641686 ! positive regulation of multicellular organism growth GO:0040018 42 31 0,000 0,02770014 0,0363967 ! hexose biosynthetic process GO:0019319 37 31 0,000 0,02770014 0,03637656 ! negative regulation of MAP kinase activity GO:0043407 57 31 0,000 0,02770014 0,03635644 ! sterol biosynthetic process GO:0016126 48 31 0,000 0,02770014 0,03633634 ! biogenic amine biosynthetic process GO:0042401 45 31 0,000 0,02770014 0,03631626 ! embryonic epithelial tube formation GO:0001838 50 31 0,000 0,02770014 0,03629621 ! tissue homeostasis GO:0001894 45 31 0,000 0,02770014 0,03627618 GO:0048871|multicellular organismal homeostasis, ! mitotic sister chromatid segregation GO:0000070 47 32 0,000 0,02858151 0,03740978 ! DNA damage checkpoint GO:0000077 57 32 0,000 0,02858151 0,03738916 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 49 32 0,000 0,02858151 0,03736856 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 45 32 0,000 0,02858151 0,03734798 ! negative regulation of protein complex assembly GO:0031333 51 32 0,000 0,02858151 0,03732743 ! regulation of synaptic plasticity GO:0048167 54 32 0,000 0,02858151 0,03730689 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 32 0,000 0,02858151 0,03728638 ! positive regulation of endocytosis GO:0045807 39 32 0,000 0,02858151 0,0372659 ! positive regulation of T cell proliferation GO:0042102 56 32 0,000 0,02858151 0,03724543 ! regulation of striated muscle tissue development GO:0016202 51 32 0,000 0,02858151 0,03722499 ! unsaturated fatty acid biosynthetic process GO:0006636 50 32 0,000 0,02858151 0,03720457 ! regulation of axonogenesis GO:0050770 60 32 0,000 0,02858151 0,03718417 ! telencephalon development GO:0021537 59 32 0,000 0,02858151 0,0371638 ! ovulation cycle GO:0042698 48 32 0,000 0,02858151 0,03714345 ! cofactor catabolic process GO:0051187 52 32 0,000 0,02858151 0,03712312 ! pyridine nucleotide metabolic process GO:0019362 49 32 0,000 0,02858151 0,03710281 ! positive regulation of catabolic process GO:0009896 44 32 0,000 0,02858151 0,03708252 ! placenta development GO:0001890 45 32 0,000 0,02858151 0,03706226 ! symbiosis, encompassing mutualism through parasitism GO:0044403 52 32 0,000 0,02858151 0,03704202 ! vesicle localization GO:0051648 50 32 0,000 0,02858151 0,0370218 ! regulation of muscle development GO:0048634 52 33 0,000 0,02946213 0,03814165 ! mRNA export from nucleus GO:0006406 47 33 0,000 0,02946213 0,03812085 ! negative regulation of secretion GO:0051048 53 33 0,000 0,02946213 0,03810007 ! negative regulation of DNA metabolic process GO:0051053 53 33 0,000 0,02946213 0,03807932 ! glial cell differentiation GO:0010001 65 33 0,000 0,02946213 0,03805859 ! cellular component assembly involved in morphogenesis GO:0010927 52 33 0,000 0,02946213 0,03803789 ! sister chromatid segregation GO:0000819 48 33 0,000 0,02946213 0,0380172 ! sphingoid metabolic process GO:0046519 51 33 0,000 0,02946213 0,03799654 ! maintenance of protein location in cell GO:0032507 66 33 0,000 0,02946213 0,0379759 ! spindle organization GO:0007051 39 33 0,000 0,02946213 0,03795529 ! pigment biosynthetic process GO:0046148 55 33 0,000 0,02946213 0,03793469 ! neutral lipid metabolic process GO:0006638 45 33 0,000 0,02946213 0,03791412 GO:0006639|acylglycerol metabolic process, ! erythrocyte differentiation GO:0030218 50 33 0,000 0,02946213 0,03789357 ! protein targeting to membrane GO:0006612 63 33 0,000 0,02946213 0,03787304 ! nucleotide catabolic process GO:0009166 47 33 0,000 0,02946213 0,03785254 ! nuclear-transcribed mRNA catabolic process GO:0000956 47 33 0,000 0,02946213 0,03783205 ! leukocyte chemotaxis GO:0030595 48 33 0,000 0,02946213 0,03781159 GO:0060326|cell chemotaxis, ! BMP signaling pathway GO:0030509 49 33 0,000 0,02946213 0,03779116 ! calcium-mediated signaling GO:0019722 54 33 0,000 0,02946213 0,03777074 ! cytokine production GO:0001816 49 33 0,000 0,02946213 0,03775034 ! regulation of microtubule-based process GO:0032886 66 33 0,000 0,02946213 0,03772997 ! RNA modification GO:0009451 43 33 0,000 0,02946213 0,03770962 ! regulation of B cell activation GO:0050864 55 33 0,000 0,02946213 0,03768929 ! positive regulation of immune effector process GO:0002699 53 33 0,000 0,02946213 0,03766899 ! negative regulation of adenylate cyclase activity GO:0007194 56 34 0,000 0,03034199 0,03877305 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! ER to Golgi vesicle-mediated transport GO:0006888 57 34 0,000 0,03034199 0,03875218 ! xenobiotic metabolic process GO:0006805 49 34 0,000 0,03034199 0,03873134 ! actomyosin structure organization GO:0031032 48 34 0,000 0,03034199 0,03871051 ! embryonic skeletal system morphogenesis GO:0048704 49 34 0,000 0,03034199 0,03868971 ! monovalent inorganic cation homeostasis GO:0055067 49 34 0,000 0,03034199 0,03866893 ! negative regulation of DNA binding GO:0043392 54 34 0,000 0,03034199 0,03864818 ! positive regulation of cell development GO:0010720 58 34 0,000 0,03034199 0,03862744 ! response to mechanical stimulus GO:0009612 46 34 0,000 0,03034199 0,03860673 ! cell fate specification GO:0001708 49 34 0,000 0,03034199 0,03858604 ! regulation of Wnt receptor signaling pathway GO:0030111 57 34 0,000 0,03034199 0,03856537 ! peripheral nervous system development GO:0007422 58 34 0,000 0,03034199 0,03854473 ! isoprenoid metabolic process GO:0006720 47 34 0,000 0,03034199 0,0385241 ! adult locomotory behavior GO:0008344 54 34 0,000 0,03034199 0,0385035 ! monosaccharide biosynthetic process GO:0046364 40 34 0,000 0,03034199 0,03848292 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 47 35 0,000 0,0312211 0,03957675 ! phosphoinositide biosynthetic process GO:0046489 54 35 0,000 0,0312211 0,03955562 ! collagen metabolic process GO:0032963 47 35 0,000 0,0312211 0,03953451 ! cell junction organization GO:0034330 72 35 0,000 0,0312211 0,03951343 ! regulation of ARF protein signal transduction GO:0032012 56 35 0,000 0,0312211 0,03949237 ! metanephros development GO:0001656 61 35 0,000 0,0312211 0,03947133 ! positive regulation of gene-specific transcription GO:0043193 53 35 0,000 0,0312211 0,03945031 ! female gonad development GO:0008585 55 35 0,000 0,0312211 0,03942931 ! lipid homeostasis GO:0055088 63 35 0,000 0,0312211 0,03940834 ! DNA integrity checkpoint GO:0031570 61 35 0,000 0,0312211 0,03938739 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,0312211 0,03936646 ! negative regulation of hydrolase activity GO:0051346 56 35 0,000 0,0312211 0,03934555 ! hindbrain development GO:0030902 56 35 0,000 0,0312211 0,03932467 ! Rho protein signal transduction GO:0007266 53 35 0,000 0,0312211 0,03930381 ! positive regulation of lymphocyte differentiation GO:0045621 51 35 0,000 0,0312211 0,03928297 ! hormone biosynthetic process GO:0042446 49 35 0,000 0,0312211 0,03926215 ! cytokinesis GO:0000910 57 35 0,000 0,0312211 0,03924136 ! embryonic organ development GO:0048568 53 35 0,000 0,0312211 0,03922058 ! pyrimidine nucleotide metabolic process GO:0006220 48 35 0,000 0,0312211 0,03919983 ! negative regulation of cell activation GO:0050866 58 35 0,000 0,0312211 0,0391791 ! protein homooligomerization GO:0051260 59 35 0,000 0,0312211 0,03915839 ! meiosis I GO:0007127 61 36 0,000 0,03209946 0,04023879 ! negative regulation of cell adhesion GO:0007162 78 36 0,000 0,03209946 0,04021754 ! regulation of metal ion transport GO:0010959 50 36 0,000 0,03209946 0,04019632 ! regulation of intracellular protein transport GO:0033157 64 36 0,000 0,03209946 0,04017512 ! development of primary male sexual characteristics GO:0046546 52 36 0,000 0,03209946 0,04015394 ! mismatch repair GO:0006298 42 36 0,000 0,03209946 0,04013278 ! regulation of action potential in neuron GO:0019228 60 36 0,000 0,03209946 0,04011165 ! glycerol ether metabolic process GO:0006662 49 36 0,000 0,03209946 0,04009054 ! regulation of proteolysis GO:0030162 53 36 0,000 0,03209946 0,04006945 ! energy coupled proton transport, down electrochemical gradient GO:0015985 55 36 0,000 0,03209946 0,04004838 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 53 36 0,000 0,03209946 0,04002734 ! dorsal/ventral pattern formation GO:0009953 50 36 0,000 0,03209946 0,04000631 ! eye morphogenesis GO:0048592 64 36 0,000 0,03209946 0,03998531 ! cellular response to insulin stimulus GO:0032869 60 36 0,000 0,03209946 0,03996433 ! regulation of smooth muscle cell proliferation GO:0048660 60 37 0,000 0,03297707 0,04103544 ! positive regulation of DNA metabolic process GO:0051054 64 37 0,000 0,03297707 0,04101393 ! mammary gland development GO:0030879 73 37 0,000 0,03297707 0,04099244 ! positive regulation of JAK-STAT cascade GO:0046427 49 37 0,000 0,03297707 0,04097098 ! ear morphogenesis GO:0042471 50 37 0,000 0,03297707 0,04094954 ! odontogenesis GO:0042476 60 37 0,000 0,03297707 0,04092813 ! negative regulation of binding GO:0051100 59 37 0,000 0,03297707 0,04090673 ! mitotic cell cycle checkpoint GO:0007093 74 37 0,000 0,03297707 0,04088536 ! tissue remodeling GO:0048771 65 37 0,000 0,03297707 0,04086401 ! carbohydrate homeostasis GO:0033500 45 37 0,000 0,03297707 0,04084268 GO:0042593|glucose homeostasis, ! keratinocyte differentiation GO:0030216 55 37 0,000 0,03297707 0,04082138 ! natural killer cell activation GO:0030101 45 37 0,000 0,03297707 0,04080009 ! polyol metabolic process GO:0019751 47 37 0,000 0,03297707 0,04077883 ! androgen receptor signaling pathway GO:0030521 66 37 0,000 0,03297707 0,04075759 ! glucan metabolic process GO:0044042 54 37 0,000 0,03297707 0,04073638 GO:0006073|cellular glucan metabolic process, ! positive regulation of transcription factor activity GO:0051091 57 38 0,000 0,03385392 0,04179779 GO:0090047|positive regulation of transcription regulator activity, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 48 38 0,000 0,03385392 0,04177605 GO:0006956|complement activation, ! regulation of hormone secretion GO:0046883 54 38 0,000 0,03385392 0,04175434 ! regulation of neuron projection development GO:0010975 73 38 0,000 0,03385392 0,04173265 ! feeding behavior GO:0007631 50 38 0,000 0,03385392 0,04171098 ! organic ether metabolic process GO:0018904 51 38 0,000 0,03385392 0,04168934 ! antigen processing and presentation of peptide antigen GO:0048002 67 38 0,000 0,03385392 0,04166771 ! development of primary female sexual characteristics GO:0046545 59 38 0,000 0,03385392 0,04164611 GO:0046660|female sex differentiation, ! regulation of Rab protein signal transduction GO:0032483 58 38 0,000 0,03385392 0,04162453 GO:0032313|regulation of Rab GTPase activity, ! multicellular organismal macromolecule metabolic process GO:0044259 51 38 0,000 0,03385392 0,04160298 ! ion transmembrane transport GO:0034220 58 38 0,000 0,03385392 0,04158144 ! heterocycle biosynthetic process GO:0018130 49 38 0,000 0,03385392 0,04155993 ! ribonucleoside metabolic process GO:0009119 51 38 0,000 0,03385392 0,04153844 ! neuron migration GO:0001764 59 38 0,000 0,03385392 0,04151698 ! maintenance of protein location GO:0045185 72 38 0,000 0,03385392 0,04149553 ! pigment metabolic process GO:0042440 66 38 0,000 0,03385392 0,04147411 ! regulation of cell morphogenesis involved in differentiation GO:0010769 72 38 0,000 0,03385392 0,04145271 ! mRNA catabolic process GO:0006402 58 39 0,000 0,03473002 0,04250353 ! response to reactive oxygen species GO:0000302 64 39 0,000 0,03473002 0,04248162 ! establishment or maintenance of cell polarity GO:0007163 74 39 0,000 0,03473002 0,04245973 ! striated muscle cell differentiation GO:0051146 58 39 0,000 0,03473002 0,04243787 ! neural tube development GO:0021915 58 39 0,000 0,03473002 0,04241603 ! polysaccharide biosynthetic process GO:0000271 51 39 0,000 0,03473002 0,04239421 ! regulation of protein stability GO:0031647 58 39 0,000 0,03473002 0,04237241 ! female gamete generation GO:0007292 50 39 0,000 0,03473002 0,04235064 ! aerobic respiration GO:0009060 56 39 0,000 0,03473002 0,04232889 ! positive regulation of leukocyte proliferation GO:0070665 64 39 0,000 0,03473002 0,04230716 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! response to xenobiotic stimulus GO:0009410 55 39 0,000 0,03473002 0,04228545 ! protein amino acid N-linked glycosylation GO:0006487 57 40 0,000 0,03560537 0,043329 ! Notch signaling pathway GO:0007219 64 40 0,000 0,03560537 0,04330679 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 68 40 0,000 0,03560537 0,04328461 ! monocarboxylic acid transport GO:0015718 68 40 0,000 0,03560537 0,04326244 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 71 40 0,000 0,03560537 0,0432403 ! hormone-mediated signaling GO:0009755 57 40 0,000 0,03560537 0,04321818 ! alcohol biosynthetic process GO:0046165 48 40 0,000 0,03560537 0,04319609 ! phagocytosis GO:0006909 65 40 0,000 0,03560537 0,04317402 ! mesenchymal cell development GO:0014031 70 40 0,000 0,03560537 0,04315197 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! erythrocyte homeostasis GO:0034101 60 40 0,000 0,03560537 0,04312994 ! B cell differentiation GO:0030183 70 40 0,000 0,03560537 0,04310793 ! pigmentation GO:0043473 81 40 0,000 0,03560537 0,04308595 ! developmental growth GO:0048589 70 40 0,000 0,03560537 0,04306399 ! synapse organization GO:0050808 61 40 0,000 0,03560537 0,04304205 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 61 41 0,000 0,03647998 0,04407687 ! RNA export from nucleus GO:0006405 57 41 0,000 0,03647998 0,04405444 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 72 41 0,000 0,03647998 0,04403203 ! detection of stimulus involved in sensory perception GO:0050906 55 41 0,000 0,03647998 0,04400965 ! regulation of epithelial cell proliferation GO:0050678 80 41 0,000 0,03647998 0,04398729 ! ATP synthesis coupled electron transport GO:0042773 50 41 0,000 0,03647998 0,04396495 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of protein secretion GO:0050708 55 41 0,000 0,03647998 0,04394263 ! cell growth GO:0016049 71 41 0,000 0,03647998 0,04392034 ! maintenance of location in cell GO:0051651 77 41 0,000 0,03647998 0,04389806 ! transforming growth factor beta receptor signaling pathway GO:0007179 59 42 0,000 0,03735383 0,04492683 ! regulation of nucleocytoplasmic transport GO:0046822 75 42 0,000 0,03735383 0,04490407 ! learning GO:0007612 75 42 0,000 0,03735383 0,04488133 ! negative regulation of protein complex disassembly GO:0043242 78 42 0,000 0,03735383 0,04485862 ! cellular amide metabolic process GO:0043603 63 42 0,000 0,03735383 0,04483593 ! morphogenesis of embryonic epithelium GO:0016331 69 42 0,000 0,03735383 0,04481326 ! gliogenesis GO:0042063 85 42 0,000 0,03735383 0,04479062 ! endosome transport GO:0016197 74 42 0,000 0,03735383 0,044768 ! induction of apoptosis by intracellular signals GO:0008629 78 42 0,000 0,03735383 0,0447454 ! male sex differentiation GO:0046661 62 42 0,000 0,03735383 0,04472282 ! double-strand break repair GO:0006302 75 42 0,000 0,03735383 0,04470027 ! epidermal cell differentiation GO:0009913 61 42 0,000 0,03735383 0,04467774 ! regulation of myeloid cell differentiation GO:0045637 78 42 0,000 0,03735383 0,04465523 ! oxidoreduction coenzyme metabolic process GO:0006733 62 42 0,000 0,03735383 0,04463275 ! mitochondrial transport GO:0006839 66 43 0,000 0,03822693 0,045653 ! protein amino acid lipidation GO:0006497 69 43 0,000 0,03822693 0,04563004 ! energy reserve metabolic process GO:0006112 67 43 0,000 0,03822693 0,04560709 ! response to calcium ion GO:0051592 65 43 0,000 0,03822693 0,04558418 ! regulation of tube size GO:0035150 69 43 0,000 0,03822693 0,04556128 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 78 43 0,000 0,03822693 0,04553841 ! regulation of T cell proliferation GO:0042129 72 43 0,000 0,03822693 0,04551556 ! positive regulation of DNA binding GO:0043388 65 43 0,000 0,03822693 0,04549273 ! T cell differentiation GO:0030217 78 43 0,000 0,03822693 0,04546993 ! icosanoid metabolic process GO:0006690 65 43 0,000 0,03822693 0,04544715 ! amino acid activation GO:0043038 61 43 0,000 0,03822693 0,04542439 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of protein transport GO:0051222 59 43 0,000 0,03822693 0,04540166 ! G1/S transition of mitotic cell cycle GO:0000082 93 44 0,000 0,03909929 0,04641451 ! epithelial cell differentiation GO:0030855 64 44 0,000 0,03909929 0,04639131 ! receptor-mediated endocytosis GO:0006898 85 44 0,000 0,03909929 0,04636812 ! cytoskeleton-dependent intracellular transport GO:0030705 78 44 0,000 0,03909929 0,04634496 ! peptide metabolic process GO:0006518 64 44 0,000 0,03909929 0,04632182 ! multicellular organismal metabolic process GO:0044236 57 44 0,000 0,03909929 0,04629871 ! inner ear development GO:0048839 66 44 0,000 0,03909929 0,04627562 ! regulation of lymphocyte mediated immunity GO:0002706 77 44 0,000 0,03909929 0,04625255 ! regulation of gene expression, epigenetic GO:0040029 86 44 0,000 0,03909929 0,0462295 ! chromatin remodeling GO:0006338 73 44 0,000 0,03909929 0,04620648 ! biopolymer methylation GO:0043414 67 44 0,000 0,03909929 0,04618348 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 58 44 0,000 0,03909929 0,0461605 ! JNK cascade GO:0007254 66 44 0,000 0,03909929 0,04613755 ! JAK-STAT cascade GO:0007259 62 44 0,000 0,03909929 0,04611462 ! regulation of cell shape GO:0008360 83 44 0,000 0,03909929 0,04609171 ! activation of adenylate cyclase activity GO:0007190 79 45 0,000 0,0399709 0,0470958 ! positive regulation of binding GO:0051099 67 45 0,000 0,0399709 0,04707243 ! positive regulation of cell cycle GO:0045787 83 45 0,000 0,0399709 0,04704908 ! stress-activated protein kinase signaling pathway GO:0031098 69 45 0,000 0,0399709 0,04702575 ! regulation of ion transport GO:0043269 60 45 0,000 0,0399709 0,04700245 ! glucose transport GO:0015758 60 45 0,000 0,0399709 0,04697917 ! neuromuscular process GO:0050905 89 45 0,000 0,0399709 0,04695591 ! positive regulation of cytokine biosynthetic process GO:0042108 61 45 0,000 0,0399709 0,04693268 ! glycosaminoglycan metabolic process GO:0030203 68 45 0,000 0,0399709 0,04690947 ! regulation of T cell differentiation GO:0045580 68 45 0,000 0,0399709 0,04688628 ! response to insulin stimulus GO:0032868 71 45 0,000 0,0399709 0,04686311 ! regulation of actin filament polymerization GO:0030833 71 46 0,000 0,04084176 0,04786049 ! regulation of JAK-STAT cascade GO:0046425 68 46 0,000 0,04084176 0,04783687 ! regulation of action potential GO:0001508 80 46 0,000 0,04084176 0,04781327 ! hexose transport GO:0008645 62 46 0,000 0,04084176 0,04778969 GO:0015749|monosaccharide transport, ! excretion GO:0007588 72 46 0,000 0,04084176 0,04776614 ! regulation of leukocyte mediated immunity GO:0002703 80 46 0,000 0,04084176 0,04774261 ! regulation of inflammatory response GO:0050727 74 46 0,000 0,04084176 0,0477191 ! epithelial tube morphogenesis GO:0060562 73 46 0,000 0,04084176 0,04769562 ! positive regulation of defense response GO:0031349 70 47 0,000 0,04171188 0,04868779 ! branching morphogenesis of a tube GO:0048754 85 47 0,000 0,04171188 0,04866386 ! embryonic skeletal system development GO:0048706 65 47 0,000 0,04171188 0,04863994 ! unsaturated fatty acid metabolic process GO:0033559 71 47 0,000 0,04171188 0,04861605 ! lipoprotein biosynthetic process GO:0042158 74 47 0,000 0,04171188 0,04859219 ! regulation of JNK cascade GO:0046328 72 47 0,000 0,04171188 0,04856834 ! response to UV GO:0009411 79 47 0,000 0,04171188 0,04854452 ! positive regulation of adenylate cyclase activity GO:0045762 90 48 0,000 0,04258125 0,04953201 ! viral infectious cycle GO:0019058 80 48 0,000 0,04258125 0,04950774 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 75 48 0,000 0,04258125 0,0494835 ! leukocyte migration GO:0050900 76 48 0,000 0,04258125 0,04945928 ! cellular amino acid biosynthetic process GO:0008652 60 48 0,000 0,04258125 0,04943508 ! striated muscle contraction GO:0006941 78 48 0,000 0,04258125 0,04941091 ! vascular process in circulatory system GO:0003018 78 48 0,000 0,04258125 0,04938676 ! DNA-dependent DNA replication GO:0006261 73 48 0,000 0,04258125 0,04936263 ! tRNA processing GO:0008033 56 48 0,000 0,04258125 0,04933853 ! cell maturation GO:0048469 69 48 0,000 0,04258125 0,04931445 ! detection of abiotic stimulus GO:0009582 66 48 0,000 0,04258125 0,04929039 ! vesicle organization GO:0016050 87 48 0,000 0,04258125 0,04926636 ! regulation of neuron apoptosis GO:0043523 84 48 0,000 0,04258125 0,04924235 ! respiratory electron transport chain GO:0022904 63 49 0,000 0,04344987 0,05022238 ! regulation of cell projection organization GO:0031344 95 49 0,000 0,04344987 0,05019793 ! glycolysis GO:0006096 63 49 0,000 0,04344987 0,0501735 ! regulation of gene-specific transcription GO:0032583 78 49 0,000 0,04344987 0,0501491 ! regulation of protein complex disassembly GO:0043244 88 49 0,000 0,04344987 0,05012472 ! induction of apoptosis by extracellular signals GO:0008624 96 49 0,000 0,04344987 0,05010036 ! endocrine system development GO:0035270 86 49 0,000 0,04344987 0,05007603 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,04344987 0,05005172 ! generation of a signal involved in cell-cell signaling GO:0003001 74 49 0,000 0,04344987 0,05002744 ! gastrulation GO:0007369 80 49 0,000 0,04344987 0,05000318 ! RNA elongation from RNA polymerase II promoter GO:0006368 65 49 0,000 0,04344987 0,04997894 ! positive regulation of cyclase activity GO:0031281 91 49 0,000 0,04344987 0,04995472 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 84 49 0,000 0,04344987 0,04993053 ! regulation of intracellular transport GO:0032386 83 49 0,000 0,04344987 0,04990637 ! methylation GO:0032259 74 49 0,000 0,04344987 0,04988222 ! cell redox homeostasis GO:0045454 72 50 0,000 0,04431776 0,05085398 ! negative regulation of cell migration GO:0030336 105 50 0,000 0,04431776 0,0508294 ! regulation of muscle contraction GO:0006937 75 50 0,000 0,04431776 0,05080485 ! cellular polysaccharide metabolic process GO:0044264 70 50 0,000 0,04431776 0,05078032 ! histone modification GO:0016570 81 50 0,000 0,04431776 0,05075581 ! positive regulation of lyase activity GO:0051349 92 50 0,000 0,04431776 0,05073132 ! heterocycle catabolic process GO:0046700 74 50 0,000 0,04431776 0,05070686 ! regulation of mast cell proliferation GO:0070666 80 50 0,000 0,04431776 0,05068243 ! RNA catabolic process GO:0006401 77 51 0,000 0,04518489 0,05164921 ! chloride transport GO:0006821 78 51 0,000 0,04518489 0,05162434 ! membrane fusion GO:0006944 82 51 0,000 0,04518489 0,0515995 ! regulation of ossification GO:0030278 82 51 0,000 0,04518489 0,05157468 ! heart morphogenesis GO:0003007 71 51 0,000 0,04518489 0,05154988 ! RNA elongation GO:0006354 67 51 0,000 0,04518489 0,05152511 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 74 51 0,000 0,04518489 0,05150036 ! aminoglycan metabolic process GO:0006022 77 52 0,000 0,04605129 0,05246265 ! activation of phospholipase C activity GO:0007202 93 52 0,000 0,04605129 0,05243748 GO:0010863|positive regulation of phospholipase C activity, ! skeletal muscle fiber development GO:0048741 79 52 0,000 0,04605129 0,05241233 ! regulation of DNA replication GO:0006275 88 52 0,000 0,04605129 0,0523872 ! immunoglobulin mediated immune response GO:0016064 72 52 0,000 0,04605129 0,0523621 GO:0019724|B cell mediated immunity, ! cell recognition GO:0008037 78 52 0,000 0,04605129 0,05233702 ! covalent chromatin modification GO:0016569 90 52 0,000 0,04605129 0,05231197 ! regulation of adaptive immune response GO:0002819 90 52 0,000 0,04605129 0,05228694 ! proton transport GO:0015992 78 52 0,000 0,04605129 0,05226193 ! negative regulation of immune system process GO:0002683 90 52 0,000 0,04605129 0,05223695 ! protein amino acid autophosphorylation GO:0046777 97 52 0,000 0,04605129 0,052212 ! transition metal ion transport GO:0000041 88 53 0,000 0,04691694 0,05316805 ! regulation of cyclin-dependent protein kinase activity GO:0000079 86 53 0,000 0,04691694 0,05314267 ! regulation of angiogenesis GO:0045765 105 53 0,000 0,04691694 0,05311732 ! muscle fiber development GO:0048747 80 53 0,000 0,04691694 0,05309199 ! sulfur compound biosynthetic process GO:0044272 71 53 0,000 0,04691694 0,05306668 ! positive regulation of phospholipase activity GO:0010518 94 53 0,000 0,04691694 0,0530414 ! cytokine-mediated signaling pathway GO:0019221 77 53 0,000 0,04691694 0,05301614 ! regulation of multicellular organism growth GO:0040014 72 53 0,000 0,04691694 0,05299091 ! regulation of endocytosis GO:0030100 71 53 0,000 0,04691694 0,0529657 ! regulation of lymphocyte differentiation GO:0045619 84 53 0,000 0,04691694 0,05294051 ! glutamine family amino acid metabolic process GO:0009064 71 53 0,000 0,04691694 0,05291535 ! cellular amino acid derivative biosynthetic process GO:0042398 73 53 0,000 0,04691694 0,05289021 ! regulation of leukocyte proliferation GO:0070663 88 53 0,000 0,04691694 0,0528651 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! maintenance of location GO:0051235 94 53 0,000 0,04691694 0,05284001 ! hydrogen transport GO:0006818 81 54 0,000 0,04778185 0,05378858 ! response to estrogen stimulus GO:0043627 88 54 0,000 0,04778185 0,05376308 ! regulation of mitosis GO:0007088 91 54 0,000 0,04778185 0,0537376 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 100 54 0,000 0,04778185 0,05371214 ! negative regulation of cytoskeleton organization GO:0051494 96 54 0,000 0,04778185 0,05368671 ! regulation of actin polymerization or depolymerization GO:0008064 81 54 0,000 0,04778185 0,0536613 ! nucleotide-excision repair GO:0006289 70 54 0,000 0,04778185 0,05363592 ! sphingolipid metabolic process GO:0006665 80 54 0,000 0,04778185 0,05361056 ! morphogenesis of a branching structure GO:0001763 99 54 0,000 0,04778185 0,05358522 ! germ cell development GO:0007281 82 54 0,000 0,04778185 0,05355991 ! positive regulation of cytokine production GO:0001819 83 54 0,000 0,04778185 0,05353462 ! regulation of protein polymerization GO:0032271 84 54 0,000 0,04778185 0,05350936 ! establishment of organelle localization GO:0051656 91 54 0,000 0,04778185 0,05348412 ! glycerophospholipid biosynthetic process GO:0046474 82 55 0,000 0,04864602 0,05442574 ! ear development GO:0043583 83 55 0,000 0,04864602 0,0544001 ! regulation of phospholipase activity GO:0010517 96 55 0,000 0,04864602 0,05437447 ! regulation of protein catabolic process GO:0042176 83 55 0,000 0,04864602 0,05434887 ! integrin-mediated signaling pathway GO:0007229 93 55 0,000 0,04864602 0,0543233 ! positive regulation of lipase activity GO:0060193 96 55 0,000 0,04864602 0,05429774 ! regulation of actin filament length GO:0030832 88 56 0,000 0,04950945 0,0552355 ! positive regulation of secretion GO:0051047 83 56 0,000 0,04950945 0,05520955 ! nucleoside metabolic process GO:0009116 74 56 0,000 0,04950945 0,05518362 ! positive regulation of organelle organization GO:0010638 95 56 0,000 0,04950945 0,05515771 ! adult behavior GO:0030534 90 56 0,000 0,04950945 0,05513182 ! cartilage development GO:0051216 84 56 0,000 0,04950945 0,05510597 ! regulation of neurotransmitter levels GO:0001505 85 57 0,000 0,05037214 0,05603989 ! mesoderm development GO:0007498 84 57 0,000 0,05037214 0,05601363 ! aging GO:0007568 91 57 0,000 0,05037214 0,05598739 ! nuclear export GO:0051168 85 57 0,000 0,05037214 0,05596118 ! cellular amino acid catabolic process GO:0009063 82 57 0,000 0,05037214 0,05593499 ! single fertilization GO:0007338 67 57 0,000 0,05037214 0,05590883 ! regulation of cellular component size GO:0032535 90 58 0,000 0,05123408 0,05683893 ! lipid modification GO:0030258 82 58 0,000 0,05123408 0,05681237 ! positive regulation of growth GO:0045927 78 58 0,000 0,05123408 0,05678584 ! DNA damage response, signal transduction GO:0042770 105 58 0,000 0,05123408 0,05675933 ! membrane lipid metabolic process GO:0006643 88 58 0,000 0,05123408 0,05673284 ! negative regulation of cell motion GO:0051271 118 58 0,000 0,05123408 0,05670638 ! regulation of bone remodeling GO:0046850 102 59 0,000 0,05209529 0,0576327 ! viral reproductive process GO:0022415 99 59 0,000 0,05209529 0,05760584 ! skeletal system morphogenesis GO:0048705 90 59 0,000 0,05209529 0,05757901 ! chromosome segregation GO:0007059 93 59 0,000 0,05209529 0,0575522 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,05209529 0,05752542 ! negative regulation of response to stimulus GO:0048585 88 59 0,000 0,05209529 0,05749867 ! cell projection assembly GO:0030031 90 59 0,000 0,05209529 0,05747193 ! glucose catabolic process GO:0006007 78 60 0,000 0,05295576 0,05839407 ! regulation of lipid metabolic process GO:0019216 93 60 0,000 0,05295576 0,05836694 ! water-soluble vitamin metabolic process GO:0006767 84 60 0,000 0,05295576 0,05833985 ! response to peptide hormone stimulus GO:0043434 97 60 0,000 0,05295576 0,05831277 ! kidney development GO:0001822 101 60 0,000 0,05295576 0,05828573 ! positive regulation of cell motion GO:0051272 110 60 0,000 0,05295576 0,05825871 ! regulation of protein complex assembly GO:0043254 95 61 0,000 0,0538155 0,0591771 ! carbohydrate transport GO:0008643 83 61 0,000 0,0538155 0,05914969 ! protein maturation by peptide bond cleavage GO:0051605 86 61 0,000 0,0538155 0,0591223 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 98 62 0,000 0,05467449 0,06003821 ! amino acid transport GO:0006865 97 62 0,000 0,05467449 0,06001044 ! negative regulation of protein kinase activity GO:0006469 110 62 0,000 0,05467449 0,0599827 ! activation of MAPK activity GO:0000187 95 62 0,000 0,05467449 0,05995498 ! multicellular organism reproduction GO:0032504 98 62 0,000 0,05467449 0,05992729 GO:0048609|reproductive process in a multicellular organism, ! lipoprotein metabolic process GO:0042157 96 62 0,000 0,05467449 0,05989962 ! glycerolipid biosynthetic process GO:0045017 92 62 0,000 0,05467449 0,05987198 ! detection of external stimulus GO:0009581 78 62 0,000 0,05467449 0,05984436 ! regulation of tissue remodeling GO:0034103 113 62 0,000 0,05467449 0,05981677 ! secondary metabolic process GO:0019748 95 62 0,000 0,05467449 0,05978921 ! gonad development GO:0008406 91 62 0,000 0,05467449 0,05976167 ! exocytosis GO:0006887 91 63 0,000 0,05553275 0,06067184 ! negative regulation of kinase activity GO:0033673 112 63 0,000 0,05553275 0,06064391 ! oxygen and reactive oxygen species metabolic process GO:0006800 89 63 0,000 0,05553275 0,06061602 ! embryonic limb morphogenesis GO:0030326 96 63 0,000 0,05553275 0,06058815 GO:0035113|embryonic appendage morphogenesis, ! coenzyme biosynthetic process GO:0009108 81 63 0,000 0,05553275 0,06056031 ! regulation of heart contraction GO:0008016 104 63 0,000 0,05553275 0,06053249 ! developmental maturation GO:0021700 90 63 0,000 0,05553275 0,0605047 ! actin filament organization GO:0007015 107 64 0,000 0,05639028 0,0614108 ! fertilization GO:0009566 79 64 0,000 0,05639028 0,06138263 ! viral reproduction GO:0016032 104 64 0,000 0,05639028 0,06135448 ! myeloid cell differentiation GO:0030099 101 64 0,000 0,05639028 0,06132637 ! amine catabolic process GO:0009310 100 65 0,000 0,05724707 0,06222963 ! negative regulation of cell growth GO:0030308 123 65 0,000 0,05724707 0,06220114 ! camera-type eye development GO:0043010 103 65 0,000 0,05724707 0,06217267 ! steroid hormone receptor signaling pathway GO:0030518 116 65 0,000 0,05724707 0,06214423 ! regulation of lipase activity GO:0060191 117 65 0,000 0,05724707 0,06211582 ! regulation of homeostatic process GO:0032844 122 65 0,000 0,05724707 0,06208743 ! organelle localization GO:0051640 105 65 0,000 0,05724707 0,06205906 ! regulation of transcription factor activity GO:0051090 109 66 0,000 0,05810312 0,06295831 GO:0090046|regulation of transcription regulator activity, ! cellular hormone metabolic process GO:0034754 95 66 0,000 0,05810312 0,06292958 ! sensory perception of smell GO:0007608 81 66 0,000 0,05810312 0,06290087 ! regulation of cytokine biosynthetic process GO:0042035 91 66 0,000 0,05810312 0,06287219 ! cAMP-mediated signaling GO:0019933 109 66 0,000 0,05810312 0,06284353 ! lung development GO:0030324 112 66 0,000 0,05810312 0,0628149 ! lymphocyte mediated immunity GO:0002449 95 66 0,000 0,05810312 0,0627863 ! B cell activation GO:0042113 119 66 0,000 0,05810312 0,06275772 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 97 66 0,000 0,05810312 0,06272917 ! negative regulation of transferase activity GO:0051348 117 66 0,000 0,05810312 0,06270064 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 96 66 0,000 0,05810312 0,06267214 ! protein oligomerization GO:0051259 109 66 0,000 0,05810312 0,06264366 ! cell cycle checkpoint GO:0000075 123 67 0,000 0,05895844 0,06353696 ! negative regulation of cell size GO:0045792 125 67 0,000 0,05895844 0,06350812 ! neurotransmitter transport GO:0006836 92 67 0,000 0,05895844 0,0634793 ! regulation of cellular response to stress GO:0080135 100 67 0,000 0,05895844 0,06345051 ! appendage morphogenesis GO:0035107 103 67 0,000 0,05895844 0,06342175 GO:0035108|limb morphogenesis, ! fatty acid biosynthetic process GO:0006633 107 67 0,000 0,05895844 0,06339301 ! extracellular matrix organization GO:0030198 117 67 0,000 0,05895844 0,0633643 ! negative regulation of ligase activity GO:0051352 100 67 0,000 0,05895844 0,06333562 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! meiosis GO:0007126 110 68 0,000 0,05981303 0,06422458 GO:0051327|M phase of meiotic cell cycle, ! phosphoinositide metabolic process GO:0030384 100 68 0,000 0,05981303 0,06419553 ! positive regulation of protein amino acid phosphorylation GO:0001934 103 68 0,000 0,05981303 0,06416651 ! defense response to bacterium GO:0042742 79 68 0,000 0,05981303 0,06413751 ! regulation of vesicle-mediated transport GO:0060627 98 68 0,000 0,05981303 0,06410854 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 109 68 0,000 0,05981303 0,0640796 ! activation of immune response GO:0002253 93 68 0,000 0,05981303 0,06405068 ! appendage development GO:0048736 108 69 0,000 0,06066688 0,06493573 GO:0060173|limb development, ! respiratory tube development GO:0030323 117 69 0,000 0,06066688 0,06490645 ! urogenital system development GO:0001655 114 69 0,000 0,06066688 0,0648772 ! meiotic cell cycle GO:0051321 111 69 0,000 0,06066688 0,06484797 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 104 70 0,000 0,06152 0,06573028 ! hexose catabolic process GO:0019320 95 70 0,000 0,06152 0,0657007 ! adaptive immune response GO:0002250 102 70 0,000 0,06152 0,06567115 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 104 71 0,000 0,06237239 0,06655111 ! elevation of cytosolic calcium ion concentration GO:0007204 126 71 0,000 0,06237239 0,0665212 ! axon guidance GO:0007411 116 71 0,000 0,06237239 0,06649132 ! intracellular receptor-mediated signaling pathway GO:0030522 124 71 0,000 0,06237239 0,06646146 ! regulation of actin cytoskeleton organization GO:0032956 120 72 0,000 0,06322405 0,06733872 ! response to drug GO:0042493 115 72 0,000 0,06322405 0,06730851 ! cytosolic calcium ion homeostasis GO:0051480 128 72 0,000 0,06322405 0,06727832 ! homeostasis of number of cells GO:0048872 109 72 0,000 0,06322405 0,06724817 ! positive regulation of T cell activation GO:0050870 117 72 0,000 0,06322405 0,06721804 ! respiratory system development GO:0060541 123 72 0,000 0,06322405 0,06718794 ! rhythmic process GO:0048511 113 72 0,000 0,06322405 0,06715786 ! regulation of immune effector process GO:0002697 121 72 0,000 0,06322405 0,06712781 ! learning or memory GO:0007611 132 73 0,000 0,06407497 0,06800085 ! humoral immune response GO:0006959 93 73 0,000 0,06407497 0,06797046 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 108 73 0,000 0,06407497 0,06794009 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 110 73 0,000 0,06407497 0,06790974 ! regulation of MAPKKK cascade GO:0043408 123 73 0,000 0,06407497 0,06787942 ! acute inflammatory response GO:0002526 107 74 0,000 0,06492517 0,06874941 ! activation of protein kinase activity GO:0032147 115 74 0,000 0,06492517 0,06871875 ! regulation of actin filament-based process GO:0032970 122 74 0,000 0,06492517 0,06868811 ! development of primary sexual characteristics GO:0045137 107 74 0,000 0,06492517 0,0686575 ! transcription initiation from RNA polymerase II promoter GO:0006367 100 74 0,000 0,06492517 0,06862692 ! regulation of neuron differentiation GO:0045664 130 74 0,000 0,06492517 0,06859636 ! regulation of Rho protein signal transduction GO:0035023 126 74 0,000 0,06492517 0,06856583 ! regulation of synaptic transmission GO:0050804 117 74 0,000 0,06492517 0,06853533 ! leukocyte mediated immunity GO:0002443 107 75 0,000 0,06577464 0,06940116 ! positive regulation of phosphorylation GO:0042327 119 75 0,000 0,06577464 0,06937032 ! inorganic anion transport GO:0015698 109 75 0,000 0,06577464 0,0693395 ! lymphocyte differentiation GO:0030098 135 75 0,000 0,06577464 0,06930871 ! regulation of catabolic process GO:0009894 114 75 0,000 0,06577464 0,06927795 ! response to metal ion GO:0010038 114 76 0,000 0,06662338 0,07014076 ! phospholipid biosynthetic process GO:0008654 109 76 0,000 0,06662338 0,07010965 ! phosphoinositide-mediated signaling GO:0048015 122 76 0,000 0,06662338 0,07007858 ! regulation of Ras GTPase activity GO:0032318 125 76 0,000 0,06662338 0,07004753 ! positive regulation of ligase activity GO:0051351 114 76 0,000 0,06662338 0,07001651 ! negative regulation of transport GO:0051051 122 77 0,000 0,06747139 0,07087632 ! cellular lipid catabolic process GO:0044242 117 77 0,000 0,06747139 0,07084496 ! positive regulation of phosphorus metabolic process GO:0010562 125 77 0,000 0,06747139 0,07081362 GO:0045937|positive regulation of phosphate metabolic process, ! response to nutrient GO:0007584 114 77 0,000 0,06747139 0,07078232 ! monosaccharide catabolic process GO:0046365 104 77 0,000 0,06747139 0,07075104 ! regulation of blood pressure GO:0008217 119 78 0,000 0,06831867 0,07160786 ! muscle cell differentiation GO:0042692 117 78 0,000 0,06831867 0,07157625 ! mitochondrion organization GO:0007005 127 78 0,000 0,06831867 0,07154466 ! negative regulation of growth GO:0045926 140 78 0,000 0,06831867 0,0715131 ! amine transport GO:0015837 115 78 0,000 0,06831867 0,07148157 ! antigen processing and presentation GO:0019882 114 78 0,000 0,06831867 0,07145007 ! regulation of ubiquitin-protein ligase activity GO:0051438 123 79 0,000 0,06916522 0,07230356 ! steroid biosynthetic process GO:0006694 111 79 0,000 0,06916522 0,07227172 ! regulation of adenylate cyclase activity GO:0045761 143 80 0,000 0,07001105 0,07312334 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 123 80 0,000 0,07001105 0,07309117 ! regulation of DNA binding GO:0051101 130 80 0,000 0,07001105 0,07305903 ! tube morphogenesis GO:0035239 140 80 0,000 0,07001105 0,07302691 ! eye development GO:0001654 130 80 0,000 0,07001105 0,07299483 ! intracellular protein transmembrane transport GO:0065002 115 80 0,000 0,07001105 0,07296277 ! protein ubiquitination GO:0016567 135 80 0,000 0,07001105 0,07293074 ! negative regulation of organelle organization GO:0010639 136 80 0,000 0,07001105 0,07289874 ! regulation of transmission of nerve impulse GO:0051969 126 80 0,000 0,07001105 0,07286677 ! response to steroid hormone stimulus GO:0048545 129 80 0,000 0,07001105 0,07283482 ! cellular response to hormone stimulus GO:0032870 125 80 0,000 0,07001105 0,0728029 ! blood coagulation GO:0007596 129 81 0,000 0,07085616 0,07364943 GO:0050817|coagulation, ! amine biosynthetic process GO:0009309 108 81 0,000 0,07085616 0,07361719 ! response to inorganic substance GO:0010035 127 81 0,000 0,07085616 0,07358497 ! oxidative phosphorylation GO:0006119 110 81 0,000 0,07085616 0,07355278 ! nitrogen compound catabolic process GO:0044270 125 81 0,000 0,07085616 0,07352062 ! response to hypoxia GO:0001666 155 81 0,000 0,07085616 0,07348849 ! regulation of protein transport GO:0051223 123 81 0,000 0,07085616 0,07345638 GO:0070201|regulation of establishment of protein localization, ! regulation of cAMP biosynthetic process GO:0030817 148 82 0,000 0,07170053 0,07429929 ! neuropeptide signaling pathway GO:0007218 101 82 0,000 0,07170053 0,07426686 ! regulation of cell morphogenesis GO:0022604 155 82 0,000 0,07170053 0,07423445 ! regulation of cyclase activity GO:0031279 146 82 0,000 0,07170053 0,07420208 ! regulation of ligase activity GO:0051340 129 82 0,000 0,07170053 0,07416973 ! cholesterol metabolic process GO:0008203 120 83 0,000 0,07254419 0,07500974 ! positive regulation of protein modification process GO:0031401 126 83 0,000 0,07254419 0,07497707 ! response to oxygen levels GO:0070482 160 83 0,000 0,07254419 0,07494443 ! regulation of cell cycle process GO:0010564 139 83 0,000 0,07254419 0,07491182 ! regulation of lyase activity GO:0051339 147 83 0,000 0,07254419 0,07487923 ! cofactor biosynthetic process GO:0051188 108 83 0,000 0,07254419 0,07484668 ! positive regulation of lymphocyte activation GO:0051251 134 83 0,000 0,07254419 0,07481415 ! regulation of cAMP metabolic process GO:0030814 153 84 0,000 0,07338712 0,07565058 ! digestion GO:0007586 111 84 0,000 0,07338712 0,07561773 ! regulation of neurological system process GO:0031644 133 84 0,000 0,07338712 0,07558491 ! ATP biosynthetic process GO:0006754 131 84 0,000 0,07338712 0,07555211 ! biogenic amine metabolic process GO:0006576 128 85 0,000 0,07422932 0,07638603 ! T cell activation GO:0042110 154 85 0,000 0,07422932 0,07635292 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 130 85 0,000 0,07422932 0,07631983 GO:0010498|proteasomal protein catabolic process, ! sex differentiation GO:0007548 126 85 0,000 0,07422932 0,07628678 ! protein import into nucleus GO:0006606 145 85 0,000 0,07422932 0,07625376 ! one-carbon metabolic process GO:0006730 126 85 0,000 0,07422932 0,07622076 ! alcohol catabolic process GO:0046164 119 86 0,000 0,0750708 0,07705148 ! carbohydrate biosynthetic process GO:0016051 111 86 0,000 0,0750708 0,07701816 ! regulation of nucleotide biosynthetic process GO:0030808 155 87 0,000 0,07591156 0,07784708 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! hemostasis GO:0007599 138 87 0,000 0,07591156 0,07781345 ! regulation of defense response GO:0031347 135 87 0,000 0,07591156 0,07777985 ! Golgi vesicle transport GO:0048193 145 87 0,000 0,07591156 0,07774628 ! tRNA metabolic process GO:0006399 110 87 0,000 0,07591156 0,07771274 ! sensory perception of chemical stimulus GO:0007606 108 87 0,000 0,07591156 0,07767923 ! gland development GO:0048732 170 87 0,000 0,07591156 0,07764575 ! interphase of mitotic cell cycle GO:0051329 166 87 0,000 0,07591156 0,0776123 ! vitamin metabolic process GO:0006766 117 87 0,000 0,07591156 0,07757887 ! forebrain development GO:0030900 151 87 0,000 0,07591156 0,07754547 ! regulation of membrane potential GO:0042391 144 88 0,000 0,0767516 0,07836986 ! ossification GO:0001503 150 89 0,000 0,07759092 0,07919279 GO:0060348|bone development, ! nucleosome assembly GO:0006334 113 89 0,000 0,07759092 0,07915875 GO:0031497|chromatin assembly, ! interphase GO:0051325 169 89 0,000 0,07759092 0,07912473 ! regulation of DNA metabolic process GO:0051052 152 90 0,000 0,07842951 0,07994555 ! microtubule cytoskeleton organization GO:0000226 133 90 0,000 0,07842951 0,07991122 ! regulation of cyclic nucleotide metabolic process GO:0030799 161 90 0,000 0,07842951 0,07987692 ! skeletal muscle tissue development GO:0007519 135 90 0,000 0,07842951 0,07984266 GO:0060538|skeletal muscle organ development, ! transcription initiation GO:0006352 128 90 0,000 0,07842951 0,07980842 ! regulation of GTPase activity GO:0043087 149 90 0,000 0,07842951 0,07977421 ! nuclear import GO:0051170 153 90 0,000 0,07842951 0,07974003 ! regulation of protein localization GO:0032880 141 90 0,000 0,07842951 0,07970588 ! positive regulation of cell activation GO:0050867 146 90 0,000 0,07842951 0,07967176 GO:0002696|positive regulation of leukocyte activation, ! carboxylic acid catabolic process GO:0046395 132 91 0,000 0,07926739 0,08048845 GO:0016054|organic acid catabolic process, ! detection of stimulus GO:0051606 123 91 0,000 0,07926739 0,08045403 ! protein localization in nucleus GO:0034504 161 92 0,000 0,08010455 0,08126896 ! sterol metabolic process GO:0016125 136 92 0,000 0,08010455 0,08123423 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 141 93 0,000 0,08094098 0,0820474 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cell cycle arrest GO:0007050 171 93 0,000 0,08094098 0,08201236 ! protein-DNA complex assembly GO:0065004 119 93 0,000 0,08094098 0,08197736 ! rRNA processing GO:0006364 124 93 0,000 0,08094098 0,08194239 ! positive regulation of MAP kinase activity GO:0043406 143 93 0,000 0,08094098 0,08190744 ! regulation of nucleotide metabolic process GO:0006140 164 93 0,000 0,08094098 0,08187253 ! anterior/posterior pattern formation GO:0009952 141 93 0,000 0,08094098 0,08183765 ! negative regulation of multicellular organismal process GO:0051241 150 93 0,000 0,08094098 0,08180279 ! leukocyte differentiation GO:0002521 165 94 0,000 0,0817767 0,08261222 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 140 94 0,000 0,0817767 0,08257707 ! ribonucleoside triphosphate biosynthetic process GO:0009201 142 94 0,000 0,0817767 0,08254195 ! rRNA metabolic process GO:0016072 125 94 0,000 0,0817767 0,08250685 ! regulation of cell adhesion GO:0030155 187 94 0,000 0,0817767 0,08247179 ! hormone metabolic process GO:0042445 135 94 0,000 0,0817767 0,08243675 ! protein processing GO:0016485 127 94 0,000 0,0817767 0,08240175 ! nucleoside triphosphate biosynthetic process GO:0009142 143 95 0,000 0,0826117 0,0832078 ! anatomical structure homeostasis GO:0060249 152 95 0,000 0,0826117 0,0831725 ! ATP metabolic process GO:0046034 150 96 0,000 0,08344599 0,08397682 ! nucleosome organization GO:0034728 126 96 0,000 0,08344599 0,08394122 ! protein modification by small protein conjugation GO:0032446 153 96 0,000 0,08344599 0,08390565 ! female pregnancy GO:0007565 148 96 0,000 0,08344599 0,08387011 ! regulation of neurogenesis GO:0050767 179 97 0,000 0,08427956 0,08467205 ! reproductive developmental process GO:0003006 149 97 0,000 0,08427956 0,08463622 ! response to virus GO:0009615 141 98 0,000 0,08511241 0,08543644 ! polysaccharide metabolic process GO:0005976 141 98 0,000 0,08511241 0,08540031 ! Wnt receptor signaling pathway GO:0016055 161 98 0,000 0,08511241 0,08536422 ! regulation of T cell activation GO:0050863 155 98 0,000 0,08511241 0,08532816 ! regulation of binding GO:0051098 164 99 0,000 0,08594454 0,08612601 ! glycerophospholipid metabolic process GO:0006650 143 99 0,000 0,08594454 0,08608966 ! cell fate commitment GO:0045165 165 99 0,000 0,08594454 0,08605333 ! positive regulation of immune response GO:0050778 143 99 0,000 0,08594454 0,08601704 ! sulfur metabolic process GO:0006790 136 99 0,000 0,08594454 0,08598078 ! carbohydrate catabolic process GO:0016052 137 100 0,000 0,08677597 0,08677597