pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/10799-0-real-Pawitan_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 2,000 2,197E-09 5,285E-06 ! nucleoside diphosphate metabolic process GO:0009132 13 9 2,000 5,269E-09 6,339E-06 ! deoxyribonucleotide metabolic process GO:0009262 32 22 2,000 9,629E-08 7,723E-05 ! regulation of translational initiation GO:0006446 82 53 2,000 1,453E-06 8,743E-04 ! tRNA processing GO:0008033 89 61 2,000 2,229E-06 1,072E-03 ! protein oligomerization GO:0051259 139 78 2,000 4,691E-06 1,881E-03 ! response to heat GO:0009408 50 30 1,000 7,431E-05 0,02554119 ! response to temperature stimulus GO:0009266 76 49 1,000 2E-04 0,06013926 ! response to unfolded protein GO:0006986 131 85 1,000 6,017E-04 0,16086449 ! response to protein stimulus GO:0051789 149 91 1,000 6,892E-04 0,16582656 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 2,157E-03 0,47169196 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 2,157E-03 0,4323843 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 2,157E-03 0,39912397 ! positive regulation of helicase activity GO:0051096 11 5 0,000 2,157E-03 0,37061511 ! neuron fate determination GO:0048664 7 5 0,000 2,157E-03 0,34590744 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 2,157E-03 0,32428822 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 2,157E-03 0,30521245 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 2,157E-03 0,2882562 ! polyol transport GO:0015791 12 5 0,000 2,157E-03 0,27308482 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 2,157E-03 0,25943058 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 2,157E-03 0,24707674 ! response to superoxide GO:0000303 10 5 0,000 2,157E-03 0,23584598 ! negative regulation of bone resorption GO:0045779 10 5 0,000 2,157E-03 0,22559181 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 2,157E-03 0,21619215 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 2,157E-03 0,20754446 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 2,157E-03 0,19956198 ! female meiosis GO:0007143 7 5 0,000 2,157E-03 0,1921708 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 2,157E-03 0,18530756 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 2,157E-03 0,17891764 ! cobalt ion transport GO:0006824 11 5 0,000 2,157E-03 0,17295372 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 2,157E-03 0,16737457 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 2,157E-03 0,16214411 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 2,157E-03 0,15723065 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 2,157E-03 0,15260622 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 2,157E-03 0,14824605 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 2,157E-03 0,1441281 ! embryonic camera-type eye development GO:0031076 10 5 0,000 2,157E-03 0,14023275 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 2,157E-03 0,13654241 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 2,157E-03 0,13304132 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 2,157E-03 0,12971529 ! adaptation of signaling pathway GO:0022401 7 5 0,000 2,157E-03 0,1265515 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 2,157E-03 0,12353837 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 2,157E-03 0,12066539 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 2,157E-03 0,11792299 ! negative chemotaxis GO:0050919 14 5 0,000 2,157E-03 0,11530248 ! positive regulation of histone modification GO:0031058 5 5 0,000 2,157E-03 0,1127959 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 2,157E-03 0,11039599 ! sensory perception of bitter taste GO:0050913 7 5 0,000 2,157E-03 0,10809607 ! behavioral response to pain GO:0048266 9 5 0,000 2,157E-03 0,10589003 ! clathrin coat assembly GO:0048268 14 5 0,000 2,157E-03 0,10377223 ! Notch receptor processing GO:0007220 8 5 0,000 2,157E-03 0,10173748 ! regulation of dopamine uptake GO:0051584 9 5 0,000 2,157E-03 0,09978099 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 2,157E-03 0,09789833 ! micturition GO:0060073 9 5 0,000 2,157E-03 0,0960854 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 2,157E-03 0,09433839 ! copulation GO:0007620 9 5 0,000 2,157E-03 0,09265378 ! glial cell fate commitment GO:0021781 13 5 0,000 2,157E-03 0,09102827 ! protein maturation by protein folding GO:0022417 13 5 0,000 2,157E-03 0,08945882 ! spermidine metabolic process GO:0008216 7 5 0,000 2,157E-03 0,08794257 ! regulation of potassium ion transport GO:0043266 10 5 0,000 2,157E-03 0,08647686 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 2,157E-03 0,08505921 ! apoptotic cell clearance GO:0043277 20 5 0,000 2,157E-03 0,08368728 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 2,157E-03 0,08235891 ! lipoprotein particle clearance GO:0034381 10 5 0,000 2,157E-03 0,08107206 ! grooming behavior GO:0007625 6 5 0,000 2,157E-03 0,07982479 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 2,157E-03 0,07861533 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 2,157E-03 0,07744196 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 2,157E-03 0,07630311 ! response to protozoan GO:0001562 10 5 0,000 2,157E-03 0,07519727 ! positive regulation of glycolysis GO:0045821 14 5 0,000 2,157E-03 0,07412302 ! lymph vessel development GO:0001945 10 5 0,000 2,157E-03 0,07307904 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 2,157E-03 0,07206405 ! endochondral ossification GO:0001958 16 5 0,000 2,157E-03 0,07107687 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 2,157E-03 0,07011637 ! parathyroid gland development GO:0060017 13 5 0,000 2,157E-03 0,06918149 ! anagen GO:0042640 6 5 0,000 2,157E-03 0,06827121 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 2,157E-03 0,06738457 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 2,157E-03 0,06652066 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 2,157E-03 0,06567863 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 2,157E-03 0,06485764 ! dorsal spinal cord development GO:0021516 7 5 0,000 2,157E-03 0,06405693 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 2,157E-03 0,06327575 ! sphingoid catabolic process GO:0046521 6 5 0,000 2,157E-03 0,06251339 ! skeletal myofibril assembly GO:0014866 10 5 0,000 2,157E-03 0,06176919 ! smooth muscle tissue development GO:0048745 28 5 0,000 2,157E-03 0,06104249 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 2,157E-03 0,06033269 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 2,157E-03 0,05963921 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 2,157E-03 0,0589615 ! cardiac muscle fiber development GO:0048739 10 5 0,000 2,157E-03 0,05829901 ! transepithelial chloride transport GO:0030321 9 5 0,000 2,157E-03 0,05765124 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 2,157E-03 0,05701771 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 2,157E-03 0,05639795 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 2,157E-03 0,05579152 ! neutrophil mediated immunity GO:0002446 7 5 0,000 2,157E-03 0,055198 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 2,157E-03 0,05461696 ! histidine catabolic process GO:0006548 6 5 0,000 2,157E-03 0,05404804 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 2,157E-03 0,05349084 ! microvillus organization GO:0032528 7 5 0,000 2,157E-03 0,05294502 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 2,157E-03 0,05241022 ! L-serine biosynthetic process GO:0006564 6 5 0,000 2,157E-03 0,05188612 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 2,157E-03 0,05137239 ! tryptophan metabolic process GO:0006568 9 5 0,000 2,157E-03 0,05086874 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 2,157E-03 0,05037487 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 2,157E-03 0,0498905 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 2,157E-03 0,04941535 ! polyol catabolic process GO:0046174 7 5 0,000 2,157E-03 0,04894917 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 2,157E-03 0,0484917 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 2,157E-03 0,0480427 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 2,157E-03 0,04760194 ! muscle cell migration GO:0014812 8 5 0,000 2,157E-03 0,0471692 ! mitochondrial fission GO:0000266 8 5 0,000 2,157E-03 0,04674425 ! sister chromatid cohesion GO:0007062 12 5 0,000 2,157E-03 0,04632689 ! mRNA transcription GO:0009299 9 5 0,000 2,157E-03 0,04591692 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 2,157E-03 0,04551414 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 2,157E-03 0,04511836 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 2,157E-03 0,04472941 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 2,157E-03 0,04434711 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 2,157E-03 0,04397128 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 2,157E-03 0,04360178 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 2,157E-03 0,04323843 ! response to food GO:0032094 6 5 0,000 2,157E-03 0,04288109 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 2,157E-03 0,0425296 ! positive regulation of transporter activity GO:0032411 8 5 0,000 2,157E-03 0,04218383 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 2,157E-03 0,04184364 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 2,157E-03 0,04150889 ! paraxial mesoderm development GO:0048339 14 5 0,000 2,157E-03 0,04117946 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 2,157E-03 0,04085521 ! forebrain neuron development GO:0021884 13 5 0,000 2,157E-03 0,04053603 ! lipoprotein catabolic process GO:0042159 11 5 0,000 2,157E-03 0,0402218 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 2,157E-03 0,0399124 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 2,157E-03 0,03960772 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 2,157E-03 0,03930766 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 2,157E-03 0,03901212 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 2,157E-03 0,03872098 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 2,157E-03 0,03843416 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 2,157E-03 0,03815156 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 2,157E-03 0,03787308 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 2,157E-03 0,03759863 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 2,157E-03 0,03732814 ! basic amino acid transport GO:0015802 11 5 0,000 2,157E-03 0,03706151 ! cellular glucose homeostasis GO:0001678 5 5 0,000 2,157E-03 0,03679866 ! early endosome to late endosome transport GO:0045022 12 5 0,000 2,157E-03 0,03653952 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 2,157E-03 0,036284 ! depyrimidination GO:0045008 10 5 0,000 2,157E-03 0,03603202 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 2,157E-03 0,03578353 ! regulation of centrosome cycle GO:0046605 7 5 0,000 2,157E-03 0,03553844 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 2,157E-03 0,03529668 ! zinc ion homeostasis GO:0055069 8 5 0,000 2,157E-03 0,03505819 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 2,157E-03 0,0348229 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 2,157E-03 0,03459074 ! forebrain morphogenesis GO:0048853 13 5 0,000 2,157E-03 0,03436167 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 2,157E-03 0,0341356 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 2,157E-03 0,03391249 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 2,157E-03 0,03369228 ! peptidyl-arginine modification GO:0018195 9 5 0,000 2,157E-03 0,03347491 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 2,157E-03 0,03326033 ! positive regulation of organ growth GO:0046622 6 5 0,000 2,157E-03 0,03304848 ! response to arsenic GO:0046685 10 5 0,000 2,157E-03 0,03283931 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 2,157E-03 0,03263278 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 2,157E-03 0,03242882 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 2,157E-03 0,0322274 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 2,157E-03 0,03202847 ! response to cadmium ion GO:0046686 7 5 0,000 2,157E-03 0,03183197 ! bile acid biosynthetic process GO:0006699 6 5 0,000 2,157E-03 0,03163788 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 2,157E-03 0,03144613 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 2,157E-03 0,0312567 ! decidualization GO:0046697 11 5 0,000 2,157E-03 0,03106953 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 2,157E-03 0,03088459 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 2,157E-03 0,03070184 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 2,157E-03 0,03052124 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 2,157E-03 0,03034276 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 2,157E-03 0,03016635 ! base conversion or substitution editing GO:0016553 5 5 0,000 2,157E-03 0,02999197 ! neural tube patterning GO:0021532 7 5 0,000 2,157E-03 0,02981961 ! embryonic cleavage GO:0040016 6 5 0,000 2,157E-03 0,02964921 ! peroxisome fission GO:0016559 5 5 0,000 2,157E-03 0,02948075 ! histone demethylation GO:0016577 10 5 0,000 2,157E-03 0,02931419 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 2,157E-03 0,0291495 ! mitotic recombination GO:0006312 9 5 0,000 2,157E-03 0,02898666 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 2,157E-03 0,02882562 ! metaphase plate congression GO:0051310 7 5 0,000 2,157E-03 0,02866636 ! regulation of sterol transport GO:0032371 7 5 0,000 2,157E-03 0,02850885 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 2,157E-03 0,02835307 ! enteric nervous system development GO:0048484 8 5 0,000 2,157E-03 0,02819898 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 2,157E-03 0,02804655 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 2,157E-03 0,02789576 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 2,157E-03 0,02774659 ! muscle cell proliferation GO:0033002 11 5 0,000 2,157E-03 0,027599 ! skeletal muscle regeneration GO:0043403 8 5 0,000 2,157E-03 0,02745297 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 2,157E-03 0,02730848 ! plasminogen activation GO:0031639 5 5 0,000 2,157E-03 0,02716551 ! B cell homeostasis GO:0001782 13 5 0,000 2,157E-03 0,02702402 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 2,157E-03 0,026884 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 2,157E-03 0,02674542 ! metaphase GO:0051323 8 5 0,000 2,157E-03 0,02660826 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 2,157E-03 0,02647251 ! cellular response to nutrient GO:0031670 8 5 0,000 2,157E-03 0,02633813 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 2,157E-03 0,02620511 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 2,157E-03 0,02607343 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 2,157E-03 0,02594306 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 2,157E-03 0,02581399 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 2,157E-03 0,0256862 ! response to redox state GO:0051775 5 5 0,000 2,157E-03 0,02555966 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 2,157E-03 0,02543437 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 2,157E-03 0,0253103 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 2,157E-03 0,02518743 ! regulation of telomerase activity GO:0051972 6 5 0,000 2,157E-03 0,02506576 ! galactolipid metabolic process GO:0019374 7 5 0,000 2,157E-03 0,02494525 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 2,157E-03 0,02482589 ! porphyrin catabolic process GO:0006787 12 5 0,000 2,157E-03 0,02470767 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 2,157E-03 0,02459058 ! striatum development GO:0021756 9 5 0,000 2,157E-03 0,02447458 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 2,157E-03 0,02435968 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 2,157E-03 0,02424585 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 2,157E-03 0,02413308 ! glial cell migration GO:0008347 11 5 0,000 2,157E-03 0,02402135 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 2,157E-03 0,02391065 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 2,157E-03 0,02380097 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 2,157E-03 0,02369229 ! somatic stem cell maintenance GO:0035019 15 5 0,000 2,157E-03 0,0235846 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 2,157E-03 0,02347788 ! negative regulation of lipase activity GO:0060192 8 5 0,000 2,157E-03 0,02337212 ! neuroprotection GO:0043526 6 5 0,000 2,157E-03 0,02326732 ! neural plate development GO:0001840 8 5 0,000 2,157E-03 0,02316344 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 2,157E-03 0,0230605 ! regulation of sensory perception GO:0051931 7 5 0,000 2,157E-03 0,02295846 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 2,157E-03 0,02285732 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 2,157E-03 0,02275707 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 2,157E-03 0,02265769 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 2,157E-03 0,02255918 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 2,157E-03 0,02246152 ! sequestering of calcium ion GO:0051208 7 5 0,000 2,157E-03 0,02236471 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 2,157E-03 0,02226872 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 2,157E-03 0,02217355 ! spindle assembly GO:0051225 6 5 0,000 2,157E-03 0,0220792 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 2,157E-03 0,02198564 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 2,157E-03 0,02189288 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 2,157E-03 0,02180089 ! drug metabolic process GO:0017144 6 5 0,000 2,157E-03 0,02170967 ! stem cell division GO:0017145 11 5 0,000 2,157E-03 0,02161921 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 2,157E-03 0,02152951 ! organ regeneration GO:0031100 7 5 0,000 2,157E-03 0,02144054 ! carnitine metabolic process GO:0009437 7 5 0,000 2,157E-03 0,02135231 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 2,157E-03 0,0212648 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 2,157E-03 0,02117801 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 2,587E-03 0,02530526 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 2,587E-03 0,02520281 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 2,587E-03 0,02510118 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 2,587E-03 0,02500038 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 2,587E-03 0,02490037 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 2,587E-03 0,02480117 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 2,587E-03 0,02470275 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 2,587E-03 0,02460511 ! sleep GO:0030431 13 6 0,000 2,587E-03 0,02450824 ! response to oxygen radical GO:0000305 11 6 0,000 2,587E-03 0,02441213 ! positive regulation of axon extension GO:0045773 11 6 0,000 2,587E-03 0,02431677 ! myoblast cell fate commitment GO:0048625 16 6 0,000 2,587E-03 0,02422215 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 2,587E-03 0,02412827 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 2,587E-03 0,02403511 ! regulation of interferon-beta production GO:0032648 8 6 0,000 2,587E-03 0,02394267 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 2,587E-03 0,02385093 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 2,587E-03 0,0237599 ! forebrain regionalization GO:0021871 8 6 0,000 2,587E-03 0,02366956 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 2,587E-03 0,0235799 ! male meiosis GO:0007140 7 6 0,000 2,587E-03 0,02349092 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 2,587E-03 0,02340261 ! response to zinc ion GO:0010043 9 6 0,000 2,587E-03 0,02331496 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 2,587E-03 0,02322796 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 2,587E-03 0,02314161 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 2,587E-03 0,0230559 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 2,587E-03 0,02297083 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 2,587E-03 0,02288637 ! malate metabolic process GO:0006108 11 6 0,000 2,587E-03 0,02280254 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 2,587E-03 0,02271932 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 2,587E-03 0,0226367 ! protein refolding GO:0042026 15 6 0,000 2,587E-03 0,02255469 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 2,587E-03 0,02247326 ! opsonization GO:0008228 8 6 0,000 2,587E-03 0,02239242 ! mating behavior GO:0007617 7 6 0,000 2,587E-03 0,02231216 ! neuron remodeling GO:0016322 15 6 0,000 2,587E-03 0,02223248 ! erythrocyte maturation GO:0043249 7 6 0,000 2,587E-03 0,02215336 ! embryonic hemopoiesis GO:0035162 14 6 0,000 2,587E-03 0,0220748 ! equilibrioception GO:0050957 14 6 0,000 2,587E-03 0,0219968 ! protein amino acid dealkylation GO:0008214 12 6 0,000 2,587E-03 0,02191934 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 2,587E-03 0,02184243 ! photoreceptor cell development GO:0042461 10 6 0,000 2,587E-03 0,02176606 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 2,587E-03 0,02169022 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 2,587E-03 0,02161491 ! response to interferon-gamma GO:0034341 15 6 0,000 2,587E-03 0,02154012 ! toxin metabolic process GO:0009404 11 6 0,000 2,587E-03 0,02146584 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 2,587E-03 0,02139207 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 2,587E-03 0,02131881 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 2,587E-03 0,02124605 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 2,587E-03 0,02117379 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 2,587E-03 0,02110201 ! cGMP-mediated signaling GO:0019934 13 6 0,000 2,587E-03 0,02103072 ! activation of MAPKKK activity GO:0000185 12 6 0,000 2,587E-03 0,02095991 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 2,587E-03 0,02088958 ! thymic T cell selection GO:0045061 12 6 0,000 2,587E-03 0,02081971 ! protein lipoylation GO:0009249 10 6 0,000 2,587E-03 0,02075031 ! cysteine metabolic process GO:0006534 10 6 0,000 2,587E-03 0,02068137 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 2,587E-03 0,02061289 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 2,587E-03 0,02054486 ! glutamate catabolic process GO:0006538 10 6 0,000 2,587E-03 0,02047728 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 2,587E-03 0,02041014 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 2,587E-03 0,02034344 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 2,587E-03 0,02027718 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 2,587E-03 0,02021134 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 2,587E-03 0,02014593 ! hyperosmotic response GO:0006972 9 6 0,000 2,587E-03 0,02008095 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 2,587E-03 0,02001638 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 2,587E-03 0,01995222 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 2,587E-03 0,01988848 ! urea metabolic process GO:0019627 7 6 0,000 2,587E-03 0,01982514 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 2,587E-03 0,0197622 ! neutrophil activation GO:0042119 8 6 0,000 2,587E-03 0,01969966 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 2,587E-03 0,01963752 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 2,587E-03 0,01957577 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 2,587E-03 0,0195144 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 2,587E-03 0,01945342 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 2,587E-03 0,01939282 ! neuron apoptosis GO:0051402 9 6 0,000 2,587E-03 0,01933259 ! nucleoside salvage GO:0043174 9 6 0,000 2,587E-03 0,01927274 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 2,587E-03 0,01921325 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 2,587E-03 0,01915413 ! T cell mediated immunity GO:0002456 16 6 0,000 2,587E-03 0,01909538 ! negative regulation of platelet activation GO:0010544 9 6 0,000 2,587E-03 0,01903698 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 2,587E-03 0,01897894 ! carnitine transport GO:0015879 10 6 0,000 2,587E-03 0,01892126 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 2,587E-03 0,01886392 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 2,587E-03 0,01880693 ! positive regulation of exocytosis GO:0045921 8 6 0,000 2,587E-03 0,01875028 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 2,587E-03 0,01869397 ! 5S class rRNA transcription GO:0042791 11 6 0,000 2,587E-03 0,018638 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 2,587E-03 0,01858237 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 2,587E-03 0,01852706 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 2,587E-03 0,01847209 ! sodium ion homeostasis GO:0055078 11 6 0,000 2,587E-03 0,01841744 ! establishment of spindle localization GO:0051293 12 6 0,000 2,587E-03 0,01836311 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 2,587E-03 0,0183091 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 2,587E-03 0,01825541 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 2,587E-03 0,01820203 ! neural nucleus development GO:0048857 14 6 0,000 2,587E-03 0,01814896 ! response to UV-C GO:0010225 11 6 0,000 2,587E-03 0,0180962 ! astrocyte development GO:0014002 15 6 0,000 2,587E-03 0,01804375 ! protein targeting to lysosome GO:0006622 10 6 0,000 2,587E-03 0,0179916 ! purine base biosynthetic process GO:0009113 17 6 0,000 2,587E-03 0,01793975 ! interaction with symbiont GO:0051702 13 6 0,000 2,587E-03 0,0178882 ! regulation of dendrite development GO:0050773 16 6 0,000 2,587E-03 0,01783694 ! skeletal muscle contraction GO:0003009 6 6 0,000 2,587E-03 0,01778598 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 2,587E-03 0,01773531 ! response to copper ion GO:0046688 10 6 0,000 2,587E-03 0,01768493 ! response to exogenous dsRNA GO:0043330 10 6 0,000 2,587E-03 0,01763483 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 2,587E-03 0,01758501 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 2,587E-03 0,01753548 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 2,587E-03 0,01748622 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 2,587E-03 0,01743724 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 2,587E-03 0,01738853 ! regulation of dopamine secretion GO:0014059 14 6 0,000 2,587E-03 0,01734009 ! nucleoside catabolic process GO:0009164 7 6 0,000 2,587E-03 0,01729193 ! hair follicle maturation GO:0048820 7 6 0,000 2,587E-03 0,01724403 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 2,587E-03 0,01719639 ! Schwann cell development GO:0014044 15 6 0,000 2,587E-03 0,01714902 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 2,587E-03 0,01710191 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 2,587E-03 0,01705505 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 2,587E-03 0,01700845 ! subpallium development GO:0021544 10 6 0,000 2,587E-03 0,01696211 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 2,587E-03 0,01691602 ! histone ubiquitination GO:0016574 8 6 0,000 2,587E-03 0,01687017 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 2,587E-03 0,01682458 ! maintenance of organ identity GO:0048496 9 6 0,000 2,587E-03 0,01677923 ! G2 phase GO:0051319 16 6 0,000 2,587E-03 0,01673412 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 2,587E-03 0,01668926 ! establishment of planar polarity GO:0001736 7 6 0,000 2,587E-03 0,01664464 ! regulation of mast cell activation GO:0033003 12 6 0,000 2,587E-03 0,01660025 ! membrane to membrane docking GO:0022614 14 6 0,000 2,587E-03 0,0165561 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 2,587E-03 0,01651218 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 2,587E-03 0,0164685 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 2,587E-03 0,01642505 ! receptor internalization GO:0031623 10 6 0,000 2,587E-03 0,01638183 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 2,587E-03 0,01633883 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 2,587E-03 0,01629606 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 2,587E-03 0,01625351 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 2,587E-03 0,01621118 ! protein deubiquitination GO:0016579 14 6 0,000 2,587E-03 0,01616907 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 2,587E-03 0,01612719 ! protein destabilization GO:0031648 9 6 0,000 2,587E-03 0,01608551 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 2,587E-03 0,01604406 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 2,587E-03 0,01600281 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 2,587E-03 0,01596178 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 2,587E-03 0,01592096 ! progesterone metabolic process GO:0042448 10 6 0,000 2,587E-03 0,01588034 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 2,587E-03 0,01583993 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 2,587E-03 0,01579973 ! negative regulation of axon extension GO:0030517 21 6 0,000 2,587E-03 0,01575973 ! removal of superoxide radicals GO:0019430 11 6 0,000 2,587E-03 0,01571993 ! triglyceride catabolic process GO:0019433 10 6 0,000 2,587E-03 0,01568034 ! determination of adult lifespan GO:0008340 15 6 0,000 2,587E-03 0,01564094 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 2,587E-03 0,01560174 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 2,587E-03 0,01556273 ! cerebellar cortex formation GO:0021697 8 6 0,000 2,587E-03 0,01552392 ! catecholamine transport GO:0051937 9 6 0,000 2,587E-03 0,01548531 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 2,587E-03 0,01544688 ! sensory cilium assembly GO:0035058 10 6 0,000 2,587E-03 0,01540865 ! organ or tissue specific immune response GO:0002251 7 6 0,000 2,587E-03 0,0153706 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 2,587E-03 0,01533274 ! maternal placenta development GO:0001893 12 6 0,000 2,587E-03 0,01529507 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 2,587E-03 0,01525758 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 2,587E-03 0,01522028 ! negative regulation of B cell activation GO:0050869 13 6 0,000 2,587E-03 0,01518316 ! protein amino acid prenylation GO:0018346 16 6 0,000 2,587E-03 0,01514621 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 2,587E-03 0,01510945 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 2,587E-03 0,01507287 ! positive regulation of coagulation GO:0050820 12 6 0,000 2,587E-03 0,01503646 ! tRNA transcription GO:0009304 14 7 0,000 3,018E-03 0,01749678 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 3,018E-03 0,01745472 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 3,018E-03 0,01741286 ! behavioral response to cocaine GO:0048148 14 7 0,000 3,018E-03 0,0173712 ! regulation of helicase activity GO:0051095 15 7 0,000 3,018E-03 0,01732974 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 3,018E-03 0,01728848 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 3,018E-03 0,01724742 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 3,018E-03 0,01720655 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 3,018E-03 0,01716587 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 3,018E-03 0,01712538 ! prostate gland development GO:0030850 13 7 0,000 3,018E-03 0,01708509 ! nucleotide-sugar transport GO:0015780 12 7 0,000 3,018E-03 0,01704498 ! synaptonemal complex assembly GO:0007130 10 7 0,000 3,018E-03 0,01700506 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 3,018E-03 0,01696533 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 3,018E-03 0,01692579 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 3,018E-03 0,01688642 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 3,018E-03 0,01684725 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 3,018E-03 0,01680825 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 3,018E-03 0,01676943 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 3,018E-03 0,01673079 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 3,018E-03 0,01669233 ! SMAD protein complex assembly GO:0007183 12 7 0,000 3,018E-03 0,01665404 ! glycolipid transport GO:0046836 10 7 0,000 3,018E-03 0,01661593 ! protein amino acid sulfation GO:0006477 10 7 0,000 3,018E-03 0,016578 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 3,018E-03 0,01654023 ! neuron adhesion GO:0007158 12 7 0,000 3,018E-03 0,01650264 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 3,018E-03 0,01646522 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 3,018E-03 0,01642797 ! actin-myosin filament sliding GO:0033275 11 7 0,000 3,018E-03 0,01639089 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 3,018E-03 0,01635397 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 3,018E-03 0,01631722 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 3,018E-03 0,01628063 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 3,018E-03 0,01624421 ! mRNA stabilization GO:0048255 18 7 0,000 3,018E-03 0,01620795 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 3,018E-03 0,01617185 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 3,018E-03 0,01613592 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 3,018E-03 0,01610014 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 3,018E-03 0,01606452 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 3,018E-03 0,01602906 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 3,018E-03 0,01599375 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 3,018E-03 0,0159586 ! lipoprotein transport GO:0042953 14 7 0,000 3,018E-03 0,0159236 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 3,018E-03 0,01588876 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 3,018E-03 0,01585407 ! rhythmic behavior GO:0007622 15 7 0,000 3,018E-03 0,01581953 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 3,018E-03 0,01578514 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 3,018E-03 0,0157509 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 3,018E-03 0,0157168 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 3,018E-03 0,01568286 ! regulation of odontogenesis GO:0042481 13 7 0,000 3,018E-03 0,01564906 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 3,018E-03 0,0156154 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 3,018E-03 0,01558189 ! mechanosensory behavior GO:0007638 14 7 0,000 3,018E-03 0,01554853 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 3,018E-03 0,0155153 ! positive regulation of isotype switching GO:0045830 15 7 0,000 3,018E-03 0,01548222 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 3,018E-03 0,01544928 ! protein-cofactor linkage GO:0018065 13 7 0,000 3,018E-03 0,01541648 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 3,018E-03 0,01538382 ! spinal cord patterning GO:0021511 13 7 0,000 3,018E-03 0,0153513 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 3,018E-03 0,01531891 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 3,018E-03 0,01528666 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 3,018E-03 0,01525454 ! adrenal gland development GO:0030325 17 7 0,000 3,018E-03 0,01522256 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 3,018E-03 0,01519072 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 3,018E-03 0,015159 ! ovulation GO:0030728 9 7 0,000 3,018E-03 0,01512742 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 3,018E-03 0,01509597 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 3,018E-03 0,01506465 ! microtubule nucleation GO:0007020 20 7 0,000 3,018E-03 0,01503346 ! proline biosynthetic process GO:0006561 10 7 0,000 3,018E-03 0,0150024 ! thyroid hormone generation GO:0006590 13 7 0,000 3,018E-03 0,01497147 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 3,018E-03 0,01494066 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 3,018E-03 0,01490998 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 3,018E-03 0,01487943 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 3,018E-03 0,014849 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 3,018E-03 0,0148187 ! galactose metabolic process GO:0006012 13 7 0,000 3,018E-03 0,01478852 ! vesicle fusion GO:0006906 17 7 0,000 3,018E-03 0,01475846 ! response to dietary excess GO:0002021 8 7 0,000 3,018E-03 0,01472852 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 3,018E-03 0,01469871 ! intracellular pH reduction GO:0051452 11 7 0,000 3,018E-03 0,01466902 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 3,018E-03 0,01463944 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 3,018E-03 0,01460999 ! organ growth GO:0035265 15 7 0,000 3,018E-03 0,01458065 ! purine salvage GO:0043101 10 7 0,000 3,018E-03 0,01455143 ! nucleoside transport GO:0015858 8 7 0,000 3,018E-03 0,01452233 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 3,018E-03 0,01449334 ! parturition GO:0007567 14 7 0,000 3,018E-03 0,01446447 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 3,018E-03 0,01443571 ! rRNA modification GO:0000154 14 7 0,000 3,018E-03 0,01440707 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 3,018E-03 0,01437854 ! spindle checkpoint GO:0031577 15 7 0,000 3,018E-03 0,01435012 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 3,018E-03 0,01432182 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 3,018E-03 0,01429363 ! macrophage differentiation GO:0030225 11 7 0,000 3,018E-03 0,01426555 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 3,018E-03 0,01423757 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 3,018E-03 0,01420971 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 3,018E-03 0,01418196 ! hyaluronan metabolic process GO:0030212 8 7 0,000 3,018E-03 0,01415431 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 3,018E-03 0,01412678 ! anterograde axon cargo transport GO:0008089 18 7 0,000 3,018E-03 0,01409934 ! fibrinolysis GO:0042730 10 7 0,000 3,018E-03 0,01407202 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 3,018E-03 0,0140448 ! eating behavior GO:0042755 7 7 0,000 3,018E-03 0,01401769 ! B cell lineage commitment GO:0002326 21 7 0,000 3,018E-03 0,01399068 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 3,018E-03 0,01396377 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 3,018E-03 0,01393697 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 3,018E-03 0,01391027 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 3,018E-03 0,01388368 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 3,018E-03 0,01385718 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 3,018E-03 0,01383079 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 3,018E-03 0,01380449 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 3,018E-03 0,0137783 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 3,018E-03 0,0137522 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 3,018E-03 0,01372621 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 3,018E-03 0,01370031 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 3,018E-03 0,01367451 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 3,018E-03 0,0136488 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 3,018E-03 0,01362319 ! regulation of meiosis GO:0040020 12 7 0,000 3,018E-03 0,01359768 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 3,018E-03 0,01357227 ! T cell lineage commitment GO:0002360 16 7 0,000 3,018E-03 0,01354695 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 3,018E-03 0,01352172 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 3,018E-03 0,01349658 ! oxygen homeostasis GO:0032364 12 7 0,000 3,018E-03 0,01347154 ! transcription termination GO:0006353 13 7 0,000 3,018E-03 0,0134466 ! response to tumor cell GO:0002347 13 7 0,000 3,018E-03 0,01342174 ! regulation of respiratory burst GO:0060263 11 7 0,000 3,018E-03 0,01339698 ! coenzyme A metabolic process GO:0015936 12 7 0,000 3,018E-03 0,01337231 ! anaphase GO:0051322 17 7 0,000 3,018E-03 0,01334773 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 3,018E-03 0,01332323 ! axonal fasciculation GO:0007413 18 7 0,000 3,018E-03 0,01329883 ! negative regulation of nuclear division GO:0051784 14 7 0,000 3,018E-03 0,01327452 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 3,018E-03 0,0132503 ! peptidyl-threonine modification GO:0018210 25 7 0,000 3,018E-03 0,01322616 ! diuresis GO:0030146 12 7 0,000 3,018E-03 0,01320211 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 3,018E-03 0,01317815 ! thiamin metabolic process GO:0006772 7 7 0,000 3,018E-03 0,01315428 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 3,018E-03 0,01313049 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 3,018E-03 0,01310679 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 3,018E-03 0,01308318 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 3,018E-03 0,01305965 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 3,018E-03 0,0130362 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 3,018E-03 0,01301284 ! melanin biosynthetic process GO:0042438 8 7 0,000 3,018E-03 0,01298956 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 3,018E-03 0,01296636 ! dopamine biosynthetic process GO:0042416 18 7 0,000 3,018E-03 0,01294325 ! glycolipid catabolic process GO:0019377 15 7 0,000 3,018E-03 0,01292022 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 3,018E-03 0,01289727 ! lymph node development GO:0048535 10 7 0,000 3,018E-03 0,0128744 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 3,018E-03 0,01285162 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 3,018E-03 0,01282891 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 3,018E-03 0,01280628 ! endosome to lysosome transport GO:0008333 11 7 0,000 3,018E-03 0,01278374 ! protein modification by small protein removal GO:0070646 16 7 0,000 3,018E-03 0,01276127 ! adult feeding behavior GO:0008343 9 7 0,000 3,018E-03 0,01273888 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 3,018E-03 0,01271657 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 3,018E-03 0,01269434 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 3,018E-03 0,01267219 ! muscle adaptation GO:0043500 14 7 0,000 3,018E-03 0,01265011 ! embryonic heart tube development GO:0035050 10 7 0,000 3,018E-03 0,01262811 ! retina homeostasis GO:0001895 12 7 0,000 3,018E-03 0,01260619 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 3,018E-03 0,01258434 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 3,018E-03 0,01256257 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 3,018E-03 0,01254087 ! protein prenylation GO:0018342 18 7 0,000 3,018E-03 0,01251925 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 3,018E-03 0,0124977 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 3,018E-03 0,01247622 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 3,018E-03 0,01245482 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 3,448E-03 0,01420688 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 3,448E-03 0,0141826 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 3,448E-03 0,01415839 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 3,448E-03 0,01413427 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 3,448E-03 0,01411024 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 3,448E-03 0,01408628 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 3,448E-03 0,0140624 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 3,448E-03 0,01403861 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 3,448E-03 0,0140149 ! neutral lipid catabolic process GO:0046461 13 8 0,000 3,448E-03 0,01399126 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 3,448E-03 0,01396771 ! meiotic prophase I GO:0007128 13 8 0,000 3,448E-03 0,01394423 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 3,448E-03 0,01392084 ! oligopeptide transport GO:0006857 15 8 0,000 3,448E-03 0,01389752 ! UTP metabolic process GO:0046051 8 8 0,000 3,448E-03 0,01387428 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 3,448E-03 0,01385112 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 3,448E-03 0,01382803 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 3,448E-03 0,01380502 ! macrophage chemotaxis GO:0048246 12 8 0,000 3,448E-03 0,01378209 ! succinate metabolic process GO:0006105 14 8 0,000 3,448E-03 0,01375924 ! membrane hyperpolarization GO:0060081 10 8 0,000 3,448E-03 0,01373645 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 3,448E-03 0,01371375 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 3,448E-03 0,01369112 ! T-helper 1 type immune response GO:0042088 12 8 0,000 3,448E-03 0,01366856 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 3,448E-03 0,01364608 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 3,448E-03 0,01362368 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 3,448E-03 0,01360134 ! ganglioside metabolic process GO:0001573 19 8 0,000 3,448E-03 0,01357908 ! reflex GO:0060004 16 8 0,000 3,448E-03 0,01355689 ! negative regulation of endocytosis GO:0045806 11 8 0,000 3,448E-03 0,01353478 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 3,448E-03 0,01351273 ! endothelial cell differentiation GO:0045446 17 8 0,000 3,448E-03 0,01349076 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 3,448E-03 0,01346886 ! glycerolipid catabolic process GO:0046503 13 8 0,000 3,448E-03 0,01344703 ! hemoglobin metabolic process GO:0020027 13 8 0,000 3,448E-03 0,01342527 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 3,448E-03 0,01340358 ! pigment granule organization GO:0048753 16 8 0,000 3,448E-03 0,01338197 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 3,448E-03 0,01336042 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 3,448E-03 0,01333894 ! astrocyte differentiation GO:0048708 18 8 0,000 3,448E-03 0,01331753 ! histidine metabolic process GO:0006547 16 8 0,000 3,448E-03 0,01329618 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 3,448E-03 0,01327491 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 3,448E-03 0,0132537 ! glycine catabolic process GO:0006546 13 8 0,000 3,448E-03 0,01323257 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 3,448E-03 0,01321149 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 3,448E-03 0,01319049 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 3,448E-03 0,01316955 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 3,448E-03 0,01314868 ! regulation of pigmentation during development GO:0048070 24 8 0,000 3,448E-03 0,01312788 ! melanin metabolic process GO:0006582 15 8 0,000 3,448E-03 0,01310714 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 3,448E-03 0,01308646 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 3,448E-03 0,01306586 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 3,448E-03 0,01304531 ! macrophage activation GO:0042116 12 8 0,000 3,448E-03 0,01302483 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 3,448E-03 0,01300442 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 3,448E-03 0,01298407 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 3,448E-03 0,01296378 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 3,448E-03 0,01294356 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 3,448E-03 0,01292339 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 3,448E-03 0,0129033 ! regulation of vascular permeability GO:0043114 12 8 0,000 3,448E-03 0,01288326 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 3,448E-03 0,01286328 ! osteoblast development GO:0002076 16 8 0,000 3,448E-03 0,01284337 ! positive regulation of vasodilation GO:0045909 13 8 0,000 3,448E-03 0,01282352 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 3,448E-03 0,01280373 ! negative regulation of translational initiation GO:0045947 10 8 0,000 3,448E-03 0,012784 ! Schwann cell differentiation GO:0014037 19 8 0,000 3,448E-03 0,01276434 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 3,448E-03 0,01274473 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 3,448E-03 0,01272518 ! response to UV-B GO:0010224 16 8 0,000 3,448E-03 0,01270569 ! protein targeting to vacuole GO:0006623 12 8 0,000 3,448E-03 0,01268627 ! protein retention in ER lumen GO:0006621 14 8 0,000 3,448E-03 0,0126669 ! intermediate filament organization GO:0045109 12 8 0,000 3,448E-03 0,01264759 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 3,448E-03 0,01262834 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 3,448E-03 0,01260915 ! cellular extravasation GO:0045123 12 8 0,000 3,448E-03 0,01259001 ! cardiac muscle cell development GO:0055013 13 8 0,000 3,448E-03 0,01257094 ! regulation of circadian rhythm GO:0042752 16 8 0,000 3,448E-03 0,01255192 ! response to antibiotic GO:0046677 11 8 0,000 3,448E-03 0,01253296 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 3,448E-03 0,01251406 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 3,448E-03 0,01249521 ! DNA topological change GO:0006265 12 8 0,000 3,448E-03 0,01247642 ! response to tropane GO:0014073 15 8 0,000 3,448E-03 0,01245769 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 3,448E-03 0,01243901 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 3,448E-03 0,01242039 ! melanosome transport GO:0032402 13 8 0,000 3,448E-03 0,01240182 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 3,448E-03 0,01238331 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 3,448E-03 0,01236486 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 3,448E-03 0,01234646 ! mast cell activation GO:0045576 14 8 0,000 3,448E-03 0,01232811 ! multicellular organismal aging GO:0010259 18 8 0,000 3,448E-03 0,01230982 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 3,448E-03 0,01229158 ! dendrite morphogenesis GO:0048813 13 8 0,000 3,448E-03 0,0122734 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 3,448E-03 0,01225527 ! nucleosome disassembly GO:0006337 14 8 0,000 3,448E-03 0,0122372 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 3,448E-03 0,01221917 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 3,448E-03 0,0122012 ! leukocyte activation during immune response GO:0002366 13 8 0,000 3,448E-03 0,01218329 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 3,448E-03 0,01216542 ! establishment of chromosome localization GO:0051303 12 8 0,000 3,448E-03 0,01214761 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 3,448E-03 0,01212985 ! intracellular lipid transport GO:0032365 13 8 0,000 3,448E-03 0,01211214 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 3,448E-03 0,01209449 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 3,448E-03 0,01207688 ! regulation of macrophage activation GO:0043030 15 8 0,000 3,448E-03 0,01205933 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 3,448E-03 0,01204183 ! positive regulation of epidermis development GO:0045684 13 8 0,000 3,448E-03 0,01202438 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 3,448E-03 0,01200697 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 3,448E-03 0,01198962 ! hormone catabolic process GO:0042447 17 8 0,000 3,448E-03 0,01197232 ! positive regulation of glucose import GO:0046326 8 8 0,000 3,448E-03 0,01195507 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 3,448E-03 0,01193787 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 3,448E-03 0,01192072 ! ATP catabolic process GO:0006200 11 8 0,000 3,448E-03 0,01190361 ! blastocyst growth GO:0001832 19 8 0,000 3,448E-03 0,01188656 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 3,448E-03 0,01186955 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 3,448E-03 0,0118526 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 3,448E-03 0,01183569 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 3,448E-03 0,01181883 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 3,448E-03 0,01180202 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 3,448E-03 0,01178525 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 3,448E-03 0,01176854 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 3,448E-03 0,01175187 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 3,448E-03 0,01173525 ! amino sugar catabolic process GO:0046348 10 8 0,000 3,448E-03 0,01171867 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 3,448E-03 0,01170214 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 3,448E-03 0,01168566 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 3,448E-03 0,01166922 ! behavioral response to nicotine GO:0035095 12 8 0,000 3,448E-03 0,01165284 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 3,448E-03 0,01163649 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 3,448E-03 0,01162019 ! NAD biosynthetic process GO:0009435 13 8 0,000 3,448E-03 0,01160394 ! regulation of developmental growth GO:0048638 15 9 0,000 3,879E-03 0,01303361 ! axon extension GO:0048675 15 9 0,000 3,879E-03 0,01301543 ! autophagic vacuole formation GO:0000045 15 9 0,000 3,879E-03 0,0129973 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 3,879E-03 0,01297922 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 3,879E-03 0,0129612 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 3,879E-03 0,01294322 ! pentose-phosphate shunt GO:0006098 16 9 0,000 3,879E-03 0,01292529 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 3,879E-03 0,01290742 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 3,879E-03 0,01288959 ! cell proliferation in forebrain GO:0021846 15 9 0,000 3,879E-03 0,01287181 ! phosphate transport GO:0006817 19 9 0,000 3,879E-03 0,01285408 ! reproductive behavior GO:0019098 19 9 0,000 3,879E-03 0,0128364 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 3,879E-03 0,01281877 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 3,879E-03 0,01280118 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 3,879E-03 0,01278365 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 3,879E-03 0,01276616 ! GTP metabolic process GO:0046039 9 9 0,000 3,879E-03 0,01274872 ! RNA methylation GO:0001510 15 9 0,000 3,879E-03 0,01273133 ! elastic fiber assembly GO:0048251 15 9 0,000 3,879E-03 0,01271398 ! induction of positive chemotaxis GO:0050930 15 9 0,000 3,879E-03 0,01269668 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 3,879E-03 0,01267943 ! artery development GO:0060840 24 9 0,000 3,879E-03 0,01266223 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 3,879E-03 0,01264507 ! regulation of glycolysis GO:0006110 21 9 0,000 3,879E-03 0,01262796 ! cerebral cortex cell migration GO:0021795 15 9 0,000 3,879E-03 0,01261089 ! keratinocyte proliferation GO:0043616 14 9 0,000 3,879E-03 0,01259388 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 3,879E-03 0,0125769 ! chemosensory behavior GO:0007635 20 9 0,000 3,879E-03 0,01255998 ! microtubule bundle formation GO:0001578 21 9 0,000 3,879E-03 0,01254309 ! middle ear morphogenesis GO:0042474 14 9 0,000 3,879E-03 0,01252626 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 3,879E-03 0,01250947 ! leukocyte degranulation GO:0043299 16 9 0,000 3,879E-03 0,01249272 ! bile acid and bile salt transport GO:0015721 13 9 0,000 3,879E-03 0,01247602 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 3,879E-03 0,01245936 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 3,879E-03 0,01244275 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 3,879E-03 0,01242618 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 3,879E-03 0,01240966 ! protein targeting to ER GO:0045047 22 9 0,000 3,879E-03 0,01239318 ! ceramide biosynthetic process GO:0046513 19 9 0,000 3,879E-03 0,01237674 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 3,879E-03 0,01236035 ! T cell selection GO:0045058 23 9 0,000 3,879E-03 0,012344 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 3,879E-03 0,01232769 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 3,879E-03 0,01231143 ! phosphagen metabolic process GO:0006599 12 9 0,000 3,879E-03 0,01229521 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 3,879E-03 0,01227903 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 3,879E-03 0,01226289 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 3,879E-03 0,0122468 ! regulation of type I interferon production GO:0032479 12 9 0,000 3,879E-03 0,01223075 ! mannose metabolic process GO:0006013 13 9 0,000 3,879E-03 0,01221474 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 3,879E-03 0,01219877 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 3,879E-03 0,01218285 ! Rac protein signal transduction GO:0016601 17 9 0,000 3,879E-03 0,01216696 ! receptor clustering GO:0043113 18 9 0,000 3,879E-03 0,01215112 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 3,879E-03 0,01213532 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 3,879E-03 0,01211956 ! ruffle organization GO:0031529 15 9 0,000 3,879E-03 0,01210384 ! retinol metabolic process GO:0042572 18 9 0,000 3,879E-03 0,01208816 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 3,879E-03 0,01207253 ! behavioral fear response GO:0001662 22 9 0,000 3,879E-03 0,01205693 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 3,879E-03 0,01204137 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 3,879E-03 0,01202585 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 3,879E-03 0,01201038 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 3,879E-03 0,01199494 ! protein heterooligomerization GO:0051291 16 9 0,000 3,879E-03 0,01197954 ! oligodendrocyte development GO:0014003 10 9 0,000 3,879E-03 0,01196418 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 3,879E-03 0,01194886 ! segment specification GO:0007379 13 9 0,000 3,879E-03 0,01193358 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 3,879E-03 0,01191834 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 3,879E-03 0,01190314 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 3,879E-03 0,01188798 ! response to amine stimulus GO:0014075 13 9 0,000 3,879E-03 0,01187285 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 3,879E-03 0,01185777 ! erythrocyte development GO:0048821 15 9 0,000 3,879E-03 0,01184272 ! gas homeostasis GO:0033483 16 9 0,000 3,879E-03 0,01182771 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 3,879E-03 0,01181274 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 3,879E-03 0,0117978 ! renal water homeostasis GO:0003091 14 9 0,000 3,879E-03 0,01178291 ! postreplication repair GO:0006301 22 9 0,000 3,879E-03 0,01176805 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 3,879E-03 0,01175323 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 3,879E-03 0,01173844 ! icosanoid secretion GO:0032309 15 9 0,000 3,879E-03 0,0117237 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 3,879E-03 0,01170899 ! cerebellum morphogenesis GO:0021587 14 9 0,000 3,879E-03 0,01169431 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 3,879E-03 0,01167968 ! regulation of cell division GO:0051302 15 9 0,000 3,879E-03 0,01166508 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 3,879E-03 0,01165051 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 3,879E-03 0,01163599 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 3,879E-03 0,0116215 ! sterol catabolic process GO:0016127 11 9 0,000 3,879E-03 0,01160704 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 3,879E-03 0,01159262 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 3,879E-03 0,01157824 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 3,879E-03 0,01156389 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 3,879E-03 0,01154958 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 3,879E-03 0,01153531 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 3,879E-03 0,01152106 ! musculoskeletal movement GO:0050881 14 9 0,000 3,879E-03 0,01150686 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 3,879E-03 0,01149269 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 3,879E-03 0,01147855 ! regulation of synaptogenesis GO:0051963 15 9 0,000 3,879E-03 0,01146445 ! purine base metabolic process GO:0006144 21 9 0,000 3,879E-03 0,01145038 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 3,879E-03 0,01143635 ! pigment granule transport GO:0051904 17 9 0,000 3,879E-03 0,01142235 ! regulation of fibrinolysis GO:0051917 16 9 0,000 3,879E-03 0,01140839 ! regulation of telomere maintenance GO:0032204 14 9 0,000 3,879E-03 0,01139446 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 3,879E-03 0,01138056 ! regulation of muscle adaptation GO:0043502 14 9 0,000 3,879E-03 0,0113667 ! regulation of amino acid transport GO:0051955 11 9 0,000 3,879E-03 0,01135287 ! mitochondrion localization GO:0051646 15 9 0,000 3,879E-03 0,01133908 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 4,309E-03 0,01258118 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 4,309E-03 0,01256593 ! negative regulation of blood pressure GO:0045776 26 10 0,000 4,309E-03 0,01255072 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 4,309E-03 0,01253554 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 4,309E-03 0,0125204 ! regulation of phosphatase activity GO:0010921 28 10 0,000 4,309E-03 0,0125053 ! synapsis GO:0007129 13 10 0,000 4,309E-03 0,01249023 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 4,309E-03 0,0124752 ! N-glycan processing GO:0006491 20 10 0,000 4,309E-03 0,01246021 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 4,309E-03 0,01244525 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 4,309E-03 0,01243033 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 4,309E-03 0,01241544 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 4,309E-03 0,01240059 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 4,309E-03 0,01238577 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 4,309E-03 0,01237099 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 4,309E-03 0,01235625 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 4,309E-03 0,01234154 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 4,309E-03 0,01232686 ! androgen metabolic process GO:0008209 17 10 0,000 4,309E-03 0,01231222 ! phospholipid efflux GO:0033700 16 10 0,000 4,309E-03 0,01229762 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 4,309E-03 0,01228305 ! positive regulation of heart contraction GO:0045823 16 10 0,000 4,309E-03 0,01226851 ! lung alveolus development GO:0048286 26 10 0,000 4,309E-03 0,01225401 ! pathogenesis GO:0009405 13 10 0,000 4,309E-03 0,01223954 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 4,309E-03 0,01222511 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 4,309E-03 0,01221071 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 4,309E-03 0,01219634 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 4,309E-03 0,01218201 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 4,309E-03 0,01216771 ! endoderm development GO:0007492 16 10 0,000 4,309E-03 0,01215345 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 4,309E-03 0,01213922 ! arginine catabolic process GO:0006527 13 10 0,000 4,309E-03 0,01212502 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 4,309E-03 0,01211086 ! proline metabolic process GO:0006560 13 10 0,000 4,309E-03 0,01209672 ! glucan biosynthetic process GO:0009250 14 10 0,000 4,309E-03 0,01208263 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 4,309E-03 0,01206856 ! polyamine biosynthetic process GO:0006596 12 10 0,000 4,309E-03 0,01205453 ! V(D)J recombination GO:0033151 28 10 0,000 4,309E-03 0,01204053 ! reverse cholesterol transport GO:0043691 16 10 0,000 4,309E-03 0,01202656 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 4,309E-03 0,01201262 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 4,309E-03 0,01199872 ! B cell proliferation GO:0042100 18 10 0,000 4,309E-03 0,01198485 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 4,309E-03 0,01197101 ! regulation of sodium ion transport GO:0002028 21 10 0,000 4,309E-03 0,0119572 ! multicellular organism growth GO:0035264 18 10 0,000 4,309E-03 0,01194342 ! phagocytosis, engulfment GO:0006911 28 10 0,000 4,309E-03 0,01192968 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 4,309E-03 0,01191597 ! epithelial cell development GO:0002064 20 10 0,000 4,309E-03 0,01190229 ! lens development in camera-type eye GO:0002088 16 10 0,000 4,309E-03 0,01188864 ! retinoic acid metabolic process GO:0042573 14 10 0,000 4,309E-03 0,01187502 ! macroautophagy GO:0016236 17 10 0,000 4,309E-03 0,01186143 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 4,309E-03 0,01184788 ! positive regulation of translational initiation GO:0045948 11 10 0,000 4,309E-03 0,01183435 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 4,309E-03 0,01182086 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 4,309E-03 0,01180739 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 4,309E-03 0,01179396 ! copper ion homeostasis GO:0055070 13 10 0,000 4,309E-03 0,01178056 ! regulation of bone resorption GO:0045124 25 10 0,000 4,309E-03 0,01176719 ! regulation of gliogenesis GO:0014013 23 10 0,000 4,309E-03 0,01175385 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 4,309E-03 0,01174054 ! alpha-beta T cell activation GO:0046631 23 10 0,000 4,309E-03 0,01172725 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 4,309E-03 0,011714 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 4,309E-03 0,01170078 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 4,309E-03 0,01168759 ! blastoderm segmentation GO:0007350 18 10 0,000 4,309E-03 0,01167443 ! response to dsRNA GO:0043331 20 10 0,000 4,309E-03 0,0116613 ! DNA ligation GO:0006266 19 10 0,000 4,309E-03 0,01164819 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 4,309E-03 0,01163512 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 4,309E-03 0,01162208 ! melanosome localization GO:0032400 16 10 0,000 4,309E-03 0,01160906 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 4,309E-03 0,01159608 ! regulation of B cell differentiation GO:0045577 19 10 0,000 4,309E-03 0,01158312 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 4,309E-03 0,01157019 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 4,309E-03 0,01155729 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 4,309E-03 0,01154442 ! mRNA cleavage GO:0006379 17 10 0,000 4,309E-03 0,01153158 ! protein sumoylation GO:0016925 15 10 0,000 4,309E-03 0,01151877 ! hindbrain morphogenesis GO:0021575 19 10 0,000 4,309E-03 0,01150599 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 4,309E-03 0,01149323 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 4,309E-03 0,0114805 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 4,309E-03 0,0114678 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 4,309E-03 0,01145513 ! salivary gland development GO:0007431 27 10 0,000 4,309E-03 0,01144249 ! prophase GO:0051324 15 10 0,000 4,309E-03 0,01142987 ! negative regulation of neurological system process GO:0031645 19 10 0,000 4,309E-03 0,01141728 ! apical protein localization GO:0045176 15 10 0,000 4,309E-03 0,01140472 ! ubiquinone metabolic process GO:0006743 15 10 0,000 4,309E-03 0,01139219 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 4,309E-03 0,01137968 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 4,309E-03 0,01136721 ! midbrain development GO:0030901 13 10 0,000 4,309E-03 0,01135476 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 4,309E-03 0,01134233 ! methionine biosynthetic process GO:0009086 19 10 0,000 4,309E-03 0,01132994 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 4,309E-03 0,01131757 ! quaternary ammonium group transport GO:0015697 21 10 0,000 4,309E-03 0,01130523 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 4,309E-03 0,01129291 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 4,309E-03 0,01128062 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 4,309E-03 0,01126836 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 4,309E-03 0,01125613 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 4,309E-03 0,01124392 ! oocyte development GO:0048599 17 10 0,000 4,309E-03 0,01123174 ! establishment of pigment granule localization GO:0051905 18 10 0,000 4,309E-03 0,01121958 ! blastocyst formation GO:0001825 17 10 0,000 4,309E-03 0,01120745 ! cerebellar cortex development GO:0021695 15 10 0,000 4,309E-03 0,01119535 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 4,309E-03 0,01118327 ! activation of innate immune response GO:0002218 12 10 0,000 4,309E-03 0,01117122 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 4,309E-03 0,0111592 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 4,309E-03 0,0111472 ! response to nicotine GO:0035094 20 10 0,000 4,309E-03 0,01113522 ! establishment of cell polarity GO:0030010 16 10 0,000 4,309E-03 0,01112328 ! negative regulation of immune effector process GO:0002698 20 10 0,000 4,309E-03 0,01111135 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 4,309E-03 0,01109946 ! localization within membrane GO:0051668 20 10 0,000 4,309E-03 0,01108759 ! negative regulation of muscle development GO:0048635 20 11 0,000 4,739E-03 0,01218089 ! respiratory burst GO:0045730 17 11 0,000 4,739E-03 0,01216789 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 4,739E-03 0,01215492 ! neuron fate specification GO:0048665 17 11 0,000 4,739E-03 0,01214197 ! telencephalon cell migration GO:0022029 20 11 0,000 4,739E-03 0,01212905 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 4,739E-03 0,01211616 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 4,739E-03 0,0121033 ! thyroid gland development GO:0030878 26 11 0,000 4,739E-03 0,01209047 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 4,739E-03 0,01207766 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 4,739E-03 0,01206488 ! Golgi vesicle budding GO:0048194 22 11 0,000 4,739E-03 0,01205213 ! response to pain GO:0048265 24 11 0,000 4,739E-03 0,0120394 ! detection of mechanical stimulus GO:0050982 22 11 0,000 4,739E-03 0,0120267 ! T cell proliferation GO:0042098 26 11 0,000 4,739E-03 0,01201403 ! blood vessel remodeling GO:0001974 29 11 0,000 4,739E-03 0,01200138 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 4,739E-03 0,01198876 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 4,739E-03 0,01197617 ! bone resorption GO:0045453 16 11 0,000 4,739E-03 0,0119636 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 4,739E-03 0,01195106 ! ventral spinal cord development GO:0021517 21 11 0,000 4,739E-03 0,01193855 ! negative regulation of proteolysis GO:0045861 25 11 0,000 4,739E-03 0,01192606 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 4,739E-03 0,0119136 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 4,739E-03 0,01190116 ! melanocyte differentiation GO:0030318 21 11 0,000 4,739E-03 0,01188875 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 4,739E-03 0,01187637 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 4,739E-03 0,01186401 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 4,739E-03 0,01185167 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 4,739E-03 0,01183937 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 4,739E-03 0,01182709 ! lipid digestion GO:0044241 18 11 0,000 4,739E-03 0,01181483 ! substrate-bound cell migration GO:0006929 13 11 0,000 4,739E-03 0,0118026 ! UV protection GO:0009650 19 11 0,000 4,739E-03 0,01179039 ! adult heart development GO:0007512 14 11 0,000 4,739E-03 0,01177821 ! chondrocyte differentiation GO:0002062 24 11 0,000 4,739E-03 0,01176606 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 4,739E-03 0,01175393 ! temperature homeostasis GO:0001659 17 11 0,000 4,739E-03 0,01174182 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 4,739E-03 0,01172974 ! negative regulation of ossification GO:0030279 26 11 0,000 4,739E-03 0,01171769 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 4,739E-03 0,01170566 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 4,739E-03 0,01169365 ! regulation of organ growth GO:0046620 13 11 0,000 4,739E-03 0,01168167 ! pigment granule localization GO:0051875 20 11 0,000 4,739E-03 0,01166971 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 4,739E-03 0,01165778 ! vasoconstriction GO:0042310 18 11 0,000 4,739E-03 0,01164587 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 4,739E-03 0,01163399 ! embryonic axis specification GO:0000578 18 11 0,000 4,739E-03 0,01162213 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 4,739E-03 0,0116103 ! snRNA metabolic process GO:0016073 24 11 0,000 4,739E-03 0,01159849 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 4,739E-03 0,0115867 ! nitric oxide metabolic process GO:0046209 15 11 0,000 4,739E-03 0,01157494 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 4,739E-03 0,0115632 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 4,739E-03 0,01155148 ! zymogen activation GO:0031638 15 11 0,000 4,739E-03 0,01153979 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 4,739E-03 0,01152812 ! neuroblast proliferation GO:0007405 24 11 0,000 4,739E-03 0,01151648 ! nucleosome positioning GO:0016584 15 11 0,000 4,739E-03 0,01150485 ! regulation of isotype switching GO:0045191 22 11 0,000 4,739E-03 0,01149326 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 4,739E-03 0,01148168 ! glutathione biosynthetic process GO:0006750 13 11 0,000 4,739E-03 0,01147013 ! regulation of leukocyte migration GO:0002685 26 11 0,000 4,739E-03 0,0114586 ! acid secretion GO:0046717 18 11 0,000 4,739E-03 0,0114471 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 4,739E-03 0,01143562 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 4,739E-03 0,01142416 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 4,739E-03 0,01141272 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 4,739E-03 0,01140131 ! oocyte differentiation GO:0009994 18 11 0,000 4,739E-03 0,01138992 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 4,739E-03 0,01137855 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 4,739E-03 0,01136721 ! cholesterol efflux GO:0033344 19 11 0,000 4,739E-03 0,01135589 ! anterior/posterior axis specification GO:0009948 18 11 0,000 4,739E-03 0,01134459 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 4,739E-03 0,01133331 ! negative regulation of glucose import GO:0046325 17 11 0,000 4,739E-03 0,01132206 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 4,739E-03 0,01131082 ! embryonic gut development GO:0048566 15 11 0,000 4,739E-03 0,01129961 ! regulation of organic acid transport GO:0032890 18 11 0,000 4,739E-03 0,01128843 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 4,739E-03 0,01127726 ! cardiac cell differentiation GO:0035051 31 11 0,000 4,739E-03 0,01126612 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 4,739E-03 0,011255 ! defense response to fungus GO:0050832 13 11 0,000 4,739E-03 0,0112439 ! developmental induction GO:0031128 19 11 0,000 4,739E-03 0,01123282 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 4,739E-03 0,01122176 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 4,739E-03 0,01121073 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 4,739E-03 0,01119972 ! sequestering of metal ion GO:0051238 14 11 0,000 4,739E-03 0,01118873 ! lamellipodium assembly GO:0030032 20 11 0,000 4,739E-03 0,01117776 ! regulation of embryonic development GO:0045995 27 11 0,000 4,739E-03 0,01116681 ! nucleus localization GO:0051647 19 11 0,000 4,739E-03 0,01115588 ! regulation of synapse organization GO:0050807 17 11 0,000 4,739E-03 0,01114498 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 5,168E-03 0,01214386 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 5,168E-03 0,01213202 ! positive regulation of blood pressure GO:0045777 17 12 0,000 5,168E-03 0,01212019 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 5,168E-03 0,01210839 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 5,168E-03 0,01209661 ! virus-host interaction GO:0019048 29 12 0,000 5,168E-03 0,01208486 ! regulation of B cell proliferation GO:0030888 20 12 0,000 5,168E-03 0,01207312 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 5,168E-03 0,01206141 ! cartilage condensation GO:0001502 20 12 0,000 5,168E-03 0,01204973 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 5,168E-03 0,01203806 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 5,168E-03 0,01202642 ! protein complex disassembly GO:0043241 27 12 0,000 5,168E-03 0,0120148 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 5,168E-03 0,0120032 ! regulation of cell projection assembly GO:0060491 30 12 0,000 5,168E-03 0,01199163 ! hippocampus development GO:0021766 26 12 0,000 5,168E-03 0,01198007 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 5,168E-03 0,01196854 ! cytokine biosynthetic process GO:0042089 21 12 0,000 5,168E-03 0,01195704 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 5,168E-03 0,01194555 ! positive regulation of cell growth GO:0030307 22 12 0,000 5,168E-03 0,01193409 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 5,168E-03 0,01192264 ! regulation of exit from mitosis GO:0007096 17 12 0,000 5,168E-03 0,01191122 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 5,168E-03 0,01189982 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 5,168E-03 0,01188845 ! drug transport GO:0015893 16 12 0,000 5,168E-03 0,01187709 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 5,168E-03 0,01186576 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 5,168E-03 0,01185445 ! tyrosine metabolic process GO:0006570 16 12 0,000 5,168E-03 0,01184316 ! polyamine metabolic process GO:0006595 17 12 0,000 5,168E-03 0,01183189 ! focal adhesion formation GO:0048041 35 12 0,000 5,168E-03 0,01182064 ! mitotic spindle organization GO:0007052 21 12 0,000 5,168E-03 0,01180942 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 5,168E-03 0,01179821 ! forebrain cell migration GO:0021885 21 12 0,000 5,168E-03 0,01178703 ! asymmetric protein localization GO:0008105 20 12 0,000 5,168E-03 0,01177587 ! membrane protein proteolysis GO:0033619 25 12 0,000 5,168E-03 0,01176473 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 5,168E-03 0,01175361 ! entry into host cell GO:0030260 32 12 0,000 5,168E-03 0,01174251 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 5,168E-03 0,01173143 ! monoamine transport GO:0015844 18 12 0,000 5,168E-03 0,01172037 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 5,168E-03 0,01170934 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 5,168E-03 0,01169832 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 5,168E-03 0,01168733 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 5,168E-03 0,01167635 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 5,168E-03 0,0116654 ! protein targeting to peroxisome GO:0006625 23 12 0,000 5,168E-03 0,01165447 ! protein homotetramerization GO:0051289 21 12 0,000 5,168E-03 0,01164356 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 5,168E-03 0,01163266 ! regulation of phagocytosis GO:0050764 16 12 0,000 5,168E-03 0,01162179 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 5,168E-03 0,01161094 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 5,168E-03 0,01160011 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 5,168E-03 0,0115893 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 5,168E-03 0,01157851 ! cranial nerve development GO:0021545 20 12 0,000 5,168E-03 0,01156774 ! fucose catabolic process GO:0019317 22 12 0,000 5,168E-03 0,01155699 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 5,168E-03 0,01154626 ! histone acetylation GO:0016573 26 12 0,000 5,168E-03 0,01153554 ! histone methylation GO:0016571 26 12 0,000 5,168E-03 0,01152485 ! mRNA polyadenylation GO:0006378 23 12 0,000 5,168E-03 0,01151418 ! autonomic nervous system development GO:0048483 24 12 0,000 5,168E-03 0,01150353 ! gland morphogenesis GO:0022612 29 12 0,000 5,168E-03 0,0114929 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 5,168E-03 0,01148229 ! peptidyl-lysine modification GO:0018205 21 12 0,000 5,168E-03 0,01147169 ! T cell homeostasis GO:0043029 25 12 0,000 5,168E-03 0,01146112 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 5,168E-03 0,01145057 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 5,168E-03 0,01144003 ! spleen development GO:0048536 22 12 0,000 5,168E-03 0,01142952 ! digestive tract morphogenesis GO:0048546 26 12 0,000 5,168E-03 0,01141902 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 5,168E-03 0,01140855 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 5,168E-03 0,01139809 ! regulation of RNA splicing GO:0043484 20 12 0,000 5,168E-03 0,01138765 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 5,168E-03 0,01137723 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 5,168E-03 0,01136683 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 5,168E-03 0,01135645 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 5,168E-03 0,01134609 ! response to cold GO:0009409 17 12 0,000 5,168E-03 0,01133575 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 5,168E-03 0,01132543 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 5,168E-03 0,01131512 ! cGMP metabolic process GO:0046068 18 13 0,000 5,598E-03 0,01224446 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 5,598E-03 0,01223334 ! regulation of chemokine production GO:0032642 18 13 0,000 5,598E-03 0,01222224 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 5,598E-03 0,01221116 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 5,598E-03 0,0122001 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 5,598E-03 0,01218906 ! lipid localization GO:0010876 28 13 0,000 5,598E-03 0,01217804 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 5,598E-03 0,01216704 ! organelle fusion GO:0048284 32 13 0,000 5,598E-03 0,01215606 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 5,598E-03 0,0121451 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 5,598E-03 0,01213415 ! pseudouridine synthesis GO:0001522 17 13 0,000 5,598E-03 0,01212323 ! endocrine pancreas development GO:0031018 22 13 0,000 5,598E-03 0,01211233 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 5,598E-03 0,01210145 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 5,598E-03 0,01209058 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 5,598E-03 0,01207974 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 5,598E-03 0,01206892 ! methionine metabolic process GO:0006555 27 13 0,000 5,598E-03 0,01205811 ! plasma membrane organization GO:0007009 24 13 0,000 5,598E-03 0,01204733 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 5,598E-03 0,01203656 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 5,598E-03 0,01202581 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 5,598E-03 0,01201509 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 5,598E-03 0,01200438 ! cell-cell junction assembly GO:0007043 27 13 0,000 5,598E-03 0,01199369 ! response to X-ray GO:0010165 25 13 0,000 5,598E-03 0,01198302 ! cytokine metabolic process GO:0042107 22 13 0,000 5,598E-03 0,01197237 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 5,598E-03 0,01196173 ! exocrine system development GO:0035272 32 13 0,000 5,598E-03 0,01195112 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 5,598E-03 0,01194052 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 5,598E-03 0,01192995 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 5,598E-03 0,01191939 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 5,598E-03 0,01190885 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 5,598E-03 0,01189833 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 5,598E-03 0,01188783 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 5,598E-03 0,01187735 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 5,598E-03 0,01186688 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 5,598E-03 0,01185644 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 5,598E-03 0,01184601 ! regulation of cellular pH GO:0030641 22 13 0,000 5,598E-03 0,0118356 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 5,598E-03 0,01182521 ! ribosome assembly GO:0042255 17 13 0,000 5,598E-03 0,01181483 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 5,598E-03 0,01180448 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 5,598E-03 0,01179414 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 5,598E-03 0,01178382 ! chromatin silencing GO:0006342 26 13 0,000 5,598E-03 0,01177352 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 5,598E-03 0,01176324 ! regulation of epidermis development GO:0045682 19 13 0,000 5,598E-03 0,01175298 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 5,598E-03 0,01174273 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 5,598E-03 0,0117325 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 5,598E-03 0,01172229 ! regulation of mRNA stability GO:0043488 31 13 0,000 5,598E-03 0,0117121 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 5,598E-03 0,01170192 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 5,598E-03 0,01169176 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 5,598E-03 0,01168162 ! mRNA 3'-end processing GO:0031124 24 13 0,000 5,598E-03 0,0116715 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 5,598E-03 0,01166139 ! embryonic placenta development GO:0001892 23 13 0,000 5,598E-03 0,01165131 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 5,598E-03 0,01164124 ! insulin secretion GO:0030073 23 13 0,000 5,598E-03 0,01163118 ! actin filament polymerization GO:0030041 24 13 0,000 5,598E-03 0,01162115 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 5,598E-03 0,01161113 ! acrosome reaction GO:0007340 18 13 0,000 5,598E-03 0,01160113 ! rRNA transcription GO:0009303 25 14 0,000 6,027E-03 0,01248029 ! lactation GO:0007595 26 14 0,000 6,027E-03 0,01246956 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 6,027E-03 0,01245884 ! reproductive cellular process GO:0048610 20 14 0,000 6,027E-03 0,01244815 ! tRNA modification GO:0006400 20 14 0,000 6,027E-03 0,01243747 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 6,027E-03 0,01242681 ! regulation of S phase GO:0033261 23 14 0,000 6,027E-03 0,01241618 ! water transport GO:0006833 21 14 0,000 6,027E-03 0,01240555 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 6,027E-03 0,01239495 ! non-recombinational repair GO:0000726 25 14 0,000 6,027E-03 0,01238437 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 6,027E-03 0,0123738 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 6,027E-03 0,01236325 ! retina development in camera-type eye GO:0060041 27 14 0,000 6,027E-03 0,01235272 ! hair follicle morphogenesis GO:0031069 26 14 0,000 6,027E-03 0,01234221 ! RNA polyadenylation GO:0043631 30 14 0,000 6,027E-03 0,01233171 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 6,027E-03 0,01232123 ! palate development GO:0060021 31 14 0,000 6,027E-03 0,01231077 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 6,027E-03 0,01230033 ! regulated secretory pathway GO:0045055 23 14 0,000 6,027E-03 0,01228991 ! regulation of mRNA processing GO:0050684 24 14 0,000 6,027E-03 0,0122795 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 6,027E-03 0,01226911 ! arginine metabolic process GO:0006525 17 14 0,000 6,027E-03 0,01225874 ! regulation of heart rate GO:0002027 24 14 0,000 6,027E-03 0,01224839 ! organic alcohol transport GO:0015850 29 14 0,000 6,027E-03 0,01223805 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 6,027E-03 0,01222773 ! negative regulation of caspase activity GO:0043154 22 14 0,000 6,027E-03 0,01221743 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 6,027E-03 0,01220715 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 6,027E-03 0,01219688 ! neutral amino acid transport GO:0015804 26 14 0,000 6,027E-03 0,01218663 ! L-amino acid transport GO:0015807 30 14 0,000 6,027E-03 0,0121764 ! bone mineralization GO:0030282 17 14 0,000 6,027E-03 0,01216619 ! stem cell development GO:0048864 43 14 0,000 6,027E-03 0,01215599 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 6,027E-03 0,01214581 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 6,027E-03 0,01213564 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 6,027E-03 0,0121255 ! cerebellum development GO:0021549 21 14 0,000 6,027E-03 0,01211537 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 6,027E-03 0,01210525 ! negative regulation of protein secretion GO:0050709 28 14 0,000 6,027E-03 0,01209516 ! response to gamma radiation GO:0010332 28 14 0,000 6,027E-03 0,01208508 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 6,027E-03 0,01207501 ! cofactor transport GO:0051181 26 14 0,000 6,027E-03 0,01206497 ! NADP metabolic process GO:0006739 24 14 0,000 6,027E-03 0,01205494 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 6,027E-03 0,01204493 ! protein-chromophore linkage GO:0018298 19 14 0,000 6,027E-03 0,01203493 ! intestinal absorption GO:0050892 25 14 0,000 6,027E-03 0,01202495 ! cAMP biosynthetic process GO:0006171 23 14 0,000 6,027E-03 0,01201499 ! oxygen transport GO:0015671 21 14 0,000 6,027E-03 0,01200504 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 6,027E-03 0,01199511 ! male genitalia development GO:0030539 24 14 0,000 6,027E-03 0,0119852 ! regulation of RNA stability GO:0043487 32 14 0,000 6,027E-03 0,0119753 ! regulation of axon extension GO:0030516 37 14 0,000 6,027E-03 0,01196542 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 6,027E-03 0,01195556 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 6,027E-03 0,01194571 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 6,457E-03 0,0127859 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 6,457E-03 0,01277538 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 6,457E-03 0,01276488 ! superoxide anion generation GO:0042554 20 15 0,000 6,457E-03 0,0127544 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 6,457E-03 0,01274394 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 6,457E-03 0,01273349 ! phospholipid catabolic process GO:0009395 22 15 0,000 6,457E-03 0,01272307 ! copper ion transport GO:0006825 20 15 0,000 6,457E-03 0,01271265 ! heterophilic cell adhesion GO:0007157 39 15 0,000 6,457E-03 0,01270226 ! cardiac muscle contraction GO:0060048 26 15 0,000 6,457E-03 0,01269188 ! sulfate transport GO:0008272 23 15 0,000 6,457E-03 0,01268152 ! response to cAMP GO:0051591 22 15 0,000 6,457E-03 0,01267118 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 6,457E-03 0,01266085 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 6,457E-03 0,01265054 ! ciliary or flagellar motility GO:0001539 20 15 0,000 6,457E-03 0,01264025 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 6,457E-03 0,01262997 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 6,457E-03 0,01261971 ! response to hexose stimulus GO:0009746 22 15 0,000 6,457E-03 0,01260947 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 6,457E-03 0,01259924 ! glycoprotein catabolic process GO:0006516 26 15 0,000 6,457E-03 0,01258903 ! pituitary gland development GO:0021983 29 15 0,000 6,457E-03 0,01257884 ! vesicle coating GO:0006901 33 15 0,000 6,457E-03 0,01256866 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 6,457E-03 0,0125585 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 6,457E-03 0,01254835 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 6,457E-03 0,01253823 ! regulation of exocytosis GO:0017157 22 15 0,000 6,457E-03 0,01252811 ! G1/S transition checkpoint GO:0031575 40 15 0,000 6,457E-03 0,01251802 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 6,457E-03 0,01250794 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 6,457E-03 0,01249788 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 6,457E-03 0,01248783 ! regulation of vasodilation GO:0042312 26 15 0,000 6,457E-03 0,0124778 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 6,457E-03 0,01246779 ! histone deacetylation GO:0016575 20 15 0,000 6,457E-03 0,01245779 ! mRNA splice site selection GO:0006376 38 15 0,000 6,457E-03 0,01244781 ! tissue regeneration GO:0042246 26 15 0,000 6,457E-03 0,01243784 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 6,457E-03 0,01242789 ! water homeostasis GO:0030104 27 15 0,000 6,457E-03 0,01241796 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 6,457E-03 0,01240804 ! muscle maintenance GO:0046716 26 15 0,000 6,457E-03 0,01239813 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 6,457E-03 0,01238825 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 6,457E-03 0,01237838 ! regulation of ATPase activity GO:0043462 21 15 0,000 6,457E-03 0,01236852 ! dopamine metabolic process GO:0042417 35 15 0,000 6,457E-03 0,01235868 ! heme biosynthetic process GO:0006783 29 15 0,000 6,457E-03 0,01234886 ! cell killing GO:0001906 29 15 0,000 6,457E-03 0,01233905 ! lymphocyte homeostasis GO:0002260 30 15 0,000 6,457E-03 0,01232926 ! detection of bacterium GO:0016045 18 15 0,000 6,457E-03 0,01231948 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 6,457E-03 0,01230972 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 6,457E-03 0,01229997 ! L-fucose metabolic process GO:0042354 30 15 0,000 6,457E-03 0,01229024 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 6,457E-03 0,01228052 ! peptide hormone processing GO:0016486 23 15 0,000 6,457E-03 0,01227082 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 6,886E-03 0,01307594 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 6,886E-03 0,01306563 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 6,886E-03 0,01305534 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 6,886E-03 0,01304506 ! dicarboxylic acid transport GO:0006835 38 16 0,000 6,886E-03 0,01303479 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 6,886E-03 0,01302454 ! bone remodeling GO:0046849 27 16 0,000 6,886E-03 0,01301431 ! filopodium assembly GO:0046847 32 16 0,000 6,886E-03 0,0130041 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 6,886E-03 0,0129939 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 6,886E-03 0,01298372 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 6,886E-03 0,01297355 ! positive regulation of ion transport GO:0043270 21 16 0,000 6,886E-03 0,0129634 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 6,886E-03 0,01295326 ! startle response GO:0001964 28 16 0,000 6,886E-03 0,01294314 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 6,886E-03 0,01293304 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 6,886E-03 0,01292295 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 6,886E-03 0,01291288 ! activation of MAPKK activity GO:0000186 35 16 0,000 6,886E-03 0,01290282 ! regulation of defense response to virus GO:0050688 27 16 0,000 6,886E-03 0,01289278 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 6,886E-03 0,01288275 ! protein polyubiquitination GO:0000209 34 16 0,000 6,886E-03 0,01287274 ! glutamate metabolic process GO:0006536 22 16 0,000 6,886E-03 0,01286275 ! complement activation, alternative pathway GO:0006957 18 16 0,000 6,886E-03 0,01285277 ! response to osmotic stress GO:0006970 25 16 0,000 6,886E-03 0,01284281 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 6,886E-03 0,01283286 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 6,886E-03 0,01282293 ! fructose metabolic process GO:0006000 25 16 0,000 6,886E-03 0,01281301 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 6,886E-03 0,01280311 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 6,886E-03 0,01279322 ! intermediate filament-based process GO:0045103 32 16 0,000 6,886E-03 0,01278335 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 6,886E-03 0,01277349 ! negative regulation of immune response GO:0050777 35 16 0,000 6,886E-03 0,01276365 ! axon cargo transport GO:0008088 43 16 0,000 6,886E-03 0,01275383 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 6,886E-03 0,01274402 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 6,886E-03 0,01273422 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 6,886E-03 0,01272444 ! DNA replication initiation GO:0006270 27 16 0,000 6,886E-03 0,01271467 ! neuron recognition GO:0008038 35 16 0,000 6,886E-03 0,01270492 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 6,886E-03 0,01269519 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 6,886E-03 0,01268547 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 6,886E-03 0,01267576 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 6,886E-03 0,01266607 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 6,886E-03 0,01265639 ! sphingolipid catabolic process GO:0030149 27 16 0,000 6,886E-03 0,01264673 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 6,886E-03 0,01263709 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 6,886E-03 0,01262745 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 6,886E-03 0,01261784 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 6,886E-03 0,01260823 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 6,886E-03 0,01259865 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 6,886E-03 0,01258907 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 6,886E-03 0,01257951 ! defense response to virus GO:0051607 37 16 0,000 6,886E-03 0,01256997 ! positive regulation of cell killing GO:0031343 32 17 0,000 7,315E-03 0,01334281 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 7,315E-03 0,0133327 ! metencephalon development GO:0022037 30 17 0,000 7,315E-03 0,01332261 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 7,315E-03 0,01331253 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 7,315E-03 0,01330247 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 7,315E-03 0,01329242 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 7,315E-03 0,01328239 ! signal complex assembly GO:0007172 41 17 0,000 7,315E-03 0,01327237 ! endothelial cell migration GO:0043542 28 17 0,000 7,315E-03 0,01326237 ! inositol metabolic process GO:0006020 28 17 0,000 7,315E-03 0,01325239 ! gene silencing by RNA GO:0031047 36 17 0,000 7,315E-03 0,01324241 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 7,315E-03 0,01323246 ! glial cell development GO:0021782 27 17 0,000 7,315E-03 0,01322251 ! limbic system development GO:0021761 36 17 0,000 7,315E-03 0,01321259 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 7,315E-03 0,01320268 ! adult walking behavior GO:0007628 33 17 0,000 7,315E-03 0,01319278 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 7,315E-03 0,0131829 ! heart looping GO:0001947 30 17 0,000 7,315E-03 0,01317303 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 7,315E-03 0,01316318 ! regulation of viral genome replication GO:0045069 28 17 0,000 7,315E-03 0,01315334 ! myoblast differentiation GO:0045445 45 17 0,000 7,315E-03 0,01314352 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 7,315E-03 0,01313371 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 7,315E-03 0,01312391 ! regulation of survival gene product expression GO:0045884 33 17 0,000 7,315E-03 0,01311413 ! cardiac muscle tissue development GO:0048738 31 17 0,000 7,315E-03 0,01310437 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 7,315E-03 0,01309462 ! glycine metabolic process GO:0006544 28 17 0,000 7,315E-03 0,01308488 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 7,315E-03 0,01307516 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 7,315E-03 0,01306545 ! NAD metabolic process GO:0019674 29 17 0,000 7,315E-03 0,01305576 ! membrane budding GO:0006900 37 17 0,000 7,315E-03 0,01304608 ! DNA integration GO:0015074 29 17 0,000 7,315E-03 0,01303642 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 7,315E-03 0,01302677 ! regulation of protein binding GO:0043393 33 17 0,000 7,315E-03 0,01301714 ! nucleobase metabolic process GO:0009112 37 17 0,000 7,315E-03 0,01300751 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 7,315E-03 0,01299791 ! DNA unwinding during replication GO:0006268 27 17 0,000 7,315E-03 0,01298832 ! genitalia development GO:0048806 30 17 0,000 7,315E-03 0,01297874 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 7,315E-03 0,01296917 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 7,315E-03 0,01295962 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 7,315E-03 0,01295009 ! neutrophil chemotaxis GO:0030593 27 17 0,000 7,315E-03 0,01294056 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 7,315E-03 0,01293106 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 7,315E-03 0,01292156 ! steroid catabolic process GO:0006706 31 17 0,000 7,315E-03 0,01291208 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 7,315E-03 0,01290262 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 7,315E-03 0,01289316 ! gas transport GO:0015669 25 17 0,000 7,315E-03 0,01288372 ! organic cation transport GO:0015695 31 17 0,000 7,315E-03 0,0128743 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 7,315E-03 0,01286489 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 7,315E-03 0,01285549 ! RNA 3'-end processing GO:0031123 34 17 0,000 7,315E-03 0,01284611 ! microspike assembly GO:0030035 36 17 0,000 7,315E-03 0,01283674 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 7,315E-03 0,01282738 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 7,315E-03 0,01281804 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 7,743E-03 0,01355946 ! neuron maturation GO:0042551 42 18 0,000 7,743E-03 0,0135496 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 7,743E-03 0,01353975 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 7,743E-03 0,01352992 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 7,743E-03 0,0135201 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 7,743E-03 0,0135103 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 7,743E-03 0,01350051 ! aminoglycan catabolic process GO:0006026 22 18 0,000 7,743E-03 0,01349073 ! memory GO:0007613 31 18 0,000 7,743E-03 0,01348097 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 7,743E-03 0,01347122 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 7,743E-03 0,01346149 ! patterning of blood vessels GO:0001569 39 18 0,000 7,743E-03 0,01345177 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 7,743E-03 0,01344207 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 7,743E-03 0,01343237 ! positive regulation of proteolysis GO:0045862 31 18 0,000 7,743E-03 0,0134227 ! epidermis morphogenesis GO:0048730 40 18 0,000 7,743E-03 0,01341303 ! glutamine metabolic process GO:0006541 29 18 0,000 7,743E-03 0,01340338 ! response to retinoic acid GO:0032526 26 18 0,000 7,743E-03 0,01339375 ! cell-substrate junction assembly GO:0007044 54 18 0,000 7,743E-03 0,01338413 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 7,743E-03 0,01337452 ! response to fungus GO:0009620 21 18 0,000 7,743E-03 0,01336492 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 7,743E-03 0,01335534 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 7,743E-03 0,01334578 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 7,743E-03 0,01333622 ! long-chain fatty acid transport GO:0015909 31 18 0,000 7,743E-03 0,01332668 ! peptide biosynthetic process GO:0043043 24 18 0,000 7,743E-03 0,01331716 ! vitamin transport GO:0051180 27 18 0,000 7,743E-03 0,01330764 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 7,743E-03 0,01329815 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 7,743E-03 0,01328866 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 7,743E-03 0,01327919 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 7,743E-03 0,01326973 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 7,743E-03 0,01326029 ! aromatic compound catabolic process GO:0019439 27 18 0,000 7,743E-03 0,01325086 ! nerve development GO:0021675 28 18 0,000 7,743E-03 0,01324144 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 7,743E-03 0,01323203 ! protein secretion GO:0009306 39 19 0,000 8,172E-03 0,01395445 ! positive regulation of translation GO:0045727 30 19 0,000 8,172E-03 0,01394456 ! negative regulation of defense response GO:0031348 25 19 0,000 8,172E-03 0,01393468 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 8,172E-03 0,01392481 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 8,172E-03 0,01391495 ! skin development GO:0043588 36 19 0,000 8,172E-03 0,01390511 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 8,172E-03 0,01389528 ! lipid phosphorylation GO:0046834 35 19 0,000 8,172E-03 0,01388547 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 8,172E-03 0,01387567 ! forelimb morphogenesis GO:0035136 32 19 0,000 8,172E-03 0,01386589 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 8,172E-03 0,01385611 ! bile acid metabolic process GO:0008206 29 19 0,000 8,172E-03 0,01384636 ! mitotic chromosome condensation GO:0007076 34 19 0,000 8,172E-03 0,01383661 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 8,172E-03 0,01382688 ! cerebral cortex development GO:0021987 36 19 0,000 8,172E-03 0,01381717 ! pigmentation during development GO:0048066 41 19 0,000 8,172E-03 0,01380746 ! cellular response to unfolded protein GO:0034620 33 19 0,000 8,172E-03 0,01379777 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 8,172E-03 0,0137881 ! heme metabolic process GO:0042168 36 19 0,000 8,172E-03 0,01377843 ! actin filament bundle formation GO:0051017 42 19 0,000 8,172E-03 0,01376879 ! neuromuscular junction development GO:0007528 34 19 0,000 8,172E-03 0,01375915 ! response to lipopolysaccharide GO:0032496 30 19 0,000 8,172E-03 0,01374953 ! plasma membrane fusion GO:0045026 28 19 0,000 8,172E-03 0,01373992 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 8,172E-03 0,01373033 ! peptide cross-linking GO:0018149 37 19 0,000 8,172E-03 0,01372074 ! protein export from nucleus GO:0006611 36 19 0,000 8,172E-03 0,01371118 ! heart process GO:0003015 30 19 0,000 8,172E-03 0,01370162 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 8,172E-03 0,01369208 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 8,172E-03 0,01368255 ! visual learning GO:0008542 36 19 0,000 8,172E-03 0,01367304 ! cellular pigmentation GO:0033059 36 19 0,000 8,172E-03 0,01366353 ! G1 phase GO:0051318 40 19 0,000 8,172E-03 0,01365405 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 8,172E-03 0,01364457 ! cell-cell junction organization GO:0045216 35 19 0,000 8,172E-03 0,01363511 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 8,172E-03 0,01362566 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 8,172E-03 0,01361622 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 8,172E-03 0,0136068 ! proximal/distal pattern formation GO:0009954 32 19 0,000 8,172E-03 0,01359739 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 8,172E-03 0,01358799 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 8,172E-03 0,01357861 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 8,172E-03 0,01356924 ! cilium assembly GO:0042384 37 19 0,000 8,172E-03 0,01355988 ! peptide hormone secretion GO:0030072 31 19 0,000 8,172E-03 0,01355054 ! protein import into nucleus, docking GO:0000059 41 20 0,000 8,6E-03 0,01425106 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 8,6E-03 0,01424125 ! positive regulation of ossification GO:0045778 47 20 0,000 8,6E-03 0,01423146 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 8,6E-03 0,01422168 ! protein amino acid deacetylation GO:0006476 29 20 0,000 8,6E-03 0,01421191 ! protein amino acid acetylation GO:0006473 39 20 0,000 8,6E-03 0,01420215 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 8,6E-03 0,01419241 ! cAMP metabolic process GO:0046058 36 20 0,000 8,6E-03 0,01418269 ! response to vitamin GO:0033273 31 20 0,000 8,6E-03 0,01417297 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 8,6E-03 0,01416327 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 8,6E-03 0,01415358 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 8,6E-03 0,01414391 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 8,6E-03 0,01413425 ! response to alkaloid GO:0043279 38 20 0,000 8,6E-03 0,0141246 ! retinoid metabolic process GO:0001523 32 20 0,000 8,6E-03 0,01411497 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 8,6E-03 0,01410534 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 8,6E-03 0,01409574 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 8,6E-03 0,01408614 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 8,6E-03 0,01407656 ! DNA duplex unwinding GO:0032508 31 20 0,000 8,6E-03 0,01406699 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 8,6E-03 0,01405743 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 8,6E-03 0,01404789 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 8,6E-03 0,01403836 ! D-ribose metabolic process GO:0006014 29 20 0,000 8,6E-03 0,01402884 ! body fluid secretion GO:0007589 31 20 0,000 8,6E-03 0,01401934 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 8,6E-03 0,01400984 ! peptide secretion GO:0002790 35 20 0,000 8,6E-03 0,01400036 ! stem cell differentiation GO:0048863 53 20 0,000 8,6E-03 0,0139909 ! behavioral interaction between organisms GO:0051705 38 20 0,000 8,6E-03 0,01398145 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 8,6E-03 0,01397201 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 8,6E-03 0,01396258 ! sensory perception of pain GO:0019233 30 20 0,000 8,6E-03 0,01395316 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 8,6E-03 0,01394376 ! diencephalon development GO:0021536 34 20 0,000 8,6E-03 0,01393437 ! protein localization in mitochondrion GO:0070585 32 20 0,000 8,6E-03 0,01392499 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 8,6E-03 0,01391563 ! detection of chemical stimulus GO:0009593 37 20 0,000 8,6E-03 0,01390628 ! peptidyl-serine modification GO:0018209 43 20 0,000 8,6E-03 0,01389694 ! positive regulation of neurological system process GO:0031646 32 20 0,000 8,6E-03 0,01388761 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 8,6E-03 0,0138783 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 8,6E-03 0,01386899 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 8,6E-03 0,0138597 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 8,6E-03 0,01385043 ! regulation of glucose import GO:0046324 29 20 0,000 8,6E-03 0,01384116 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 8,6E-03 0,01383191 ! actin filament-based movement GO:0030048 43 20 0,000 8,6E-03 0,01382267 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 8,6E-03 0,01381344 ! negative regulation of T cell activation GO:0050868 40 20 0,000 8,6E-03 0,01380423 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 8,6E-03 0,01379503 ! negative regulation of translation GO:0017148 29 20 0,000 8,6E-03 0,01378584 ! negative regulation of coagulation GO:0050819 29 20 0,000 8,6E-03 0,01377666 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 8,6E-03 0,01376749 ! regulation of cell killing GO:0031341 42 21 0,000 9,029E-03 0,01444338 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 9,029E-03 0,01443378 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 9,029E-03 0,0144242 ! hormone secretion GO:0046879 38 21 0,000 9,029E-03 0,01441463 ! glycerol metabolic process GO:0006071 34 21 0,000 9,029E-03 0,01440507 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 9,029E-03 0,01439552 ! hindlimb morphogenesis GO:0035137 43 21 0,000 9,029E-03 0,01438599 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 9,029E-03 0,01437647 ! axis specification GO:0009798 38 21 0,000 9,029E-03 0,01436696 ! ovarian follicle development GO:0001541 35 21 0,000 9,029E-03 0,01435746 ! inactivation of MAPK activity GO:0000188 39 21 0,000 9,029E-03 0,01434798 ! smooth muscle contraction GO:0006939 46 21 0,000 9,029E-03 0,01433851 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 9,029E-03 0,01432905 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 9,029E-03 0,01431961 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 9,029E-03 0,01431017 ! cell aging GO:0007569 44 21 0,000 9,029E-03 0,01430075 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 9,029E-03 0,01429134 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 9,029E-03 0,01428195 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 9,029E-03 0,01427256 ! cytolysis GO:0019835 24 21 0,000 9,029E-03 0,01426319 ! vasodilation GO:0042311 39 21 0,000 9,029E-03 0,01425383 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 9,029E-03 0,01424449 ! regulation of vasoconstriction GO:0019229 39 21 0,000 9,029E-03 0,01423515 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 9,029E-03 0,01422583 ! oogenesis GO:0048477 36 21 0,000 9,029E-03 0,01421652 ! DNA modification GO:0006304 34 21 0,000 9,029E-03 0,01420722 ! positive regulation of locomotion GO:0040017 39 21 0,000 9,029E-03 0,01419794 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 9,029E-03 0,01418866 ! detection of biotic stimulus GO:0009595 29 21 0,000 9,029E-03 0,0141794 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 9,029E-03 0,01417015 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 9,029E-03 0,01416091 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 9,029E-03 0,01415169 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 9,029E-03 0,01414247 ! vitamin A metabolic process GO:0006776 33 21 0,000 9,029E-03 0,01413327 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 9,029E-03 0,01412408 ! response to cytokine stimulus GO:0034097 63 21 0,000 9,029E-03 0,01411491 ! terpenoid metabolic process GO:0006721 37 21 0,000 9,029E-03 0,01410574 ! collagen catabolic process GO:0030574 28 21 0,000 9,029E-03 0,01409659 ! sperm-egg recognition GO:0035036 21 21 0,000 9,029E-03 0,01408745 ! gut development GO:0048565 39 21 0,000 9,029E-03 0,01407832 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 9,457E-03 0,01473623 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 9,457E-03 0,01472669 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 9,457E-03 0,01471716 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 9,457E-03 0,01470765 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 9,457E-03 0,01469815 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 9,457E-03 0,01468866 ! regulation of chemotaxis GO:0050920 40 22 0,000 9,457E-03 0,01467918 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 9,457E-03 0,01466972 ! glutamate signaling pathway GO:0007215 41 22 0,000 9,457E-03 0,01466027 ! regeneration GO:0031099 41 22 0,000 9,457E-03 0,01465083 ! keratinization GO:0031424 28 22 0,000 9,457E-03 0,0146414 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 9,457E-03 0,01463198 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 9,457E-03 0,01462258 ! sensory perception of taste GO:0050909 28 22 0,000 9,457E-03 0,01461319 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 9,457E-03 0,01460381 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 9,457E-03 0,01459444 ! vacuolar transport GO:0007034 36 22 0,000 9,457E-03 0,01458508 ! lysosome organization GO:0007040 41 22 0,000 9,457E-03 0,01457574 ! central nervous system neuron development GO:0021954 46 22 0,000 9,457E-03 0,01456641 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 9,457E-03 0,01455709 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 9,457E-03 0,01454778 ! fucose metabolic process GO:0006004 39 22 0,000 9,457E-03 0,01453849 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 9,457E-03 0,0145292 ! apoptotic nuclear changes GO:0030262 32 22 0,000 9,457E-03 0,01451993 ! ureteric bud development GO:0001657 43 22 0,000 9,457E-03 0,01451067 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 9,457E-03 0,01450142 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 9,457E-03 0,01449219 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 9,457E-03 0,01448296 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 9,457E-03 0,01447375 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 9,457E-03 0,01446455 ! regulation of cytokine secretion GO:0050707 37 22 0,000 9,457E-03 0,01445536 ! sarcomere organization GO:0045214 30 22 0,000 9,457E-03 0,01444618 ! positive regulation of B cell activation GO:0050871 38 22 0,000 9,457E-03 0,01443701 ! activation of JUN kinase activity GO:0007257 42 22 0,000 9,457E-03 0,01442786 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 9,457E-03 0,01441872 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 9,457E-03 0,01440958 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 9,457E-03 0,01440046 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 9,457E-03 0,01439136 ! protein stabilization GO:0050821 39 22 0,000 9,457E-03 0,01438226 ! positive regulation of DNA replication GO:0045740 43 23 0,000 9,885E-03 0,01502351 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 9,885E-03 0,01501402 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 9,885E-03 0,01500455 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 9,885E-03 0,01499509 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 9,885E-03 0,01498564 ! gluconeogenesis GO:0006094 33 23 0,000 9,885E-03 0,0149762 ! viral genome replication GO:0019079 41 23 0,000 9,885E-03 0,01496678 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 9,885E-03 0,01495737 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 9,885E-03 0,01494797 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 9,885E-03 0,01493858 ! glucosamine metabolic process GO:0006041 30 23 0,000 9,885E-03 0,0149292 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 9,885E-03 0,01491983 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 9,885E-03 0,01491048 ! visual behavior GO:0007632 42 23 0,000 9,885E-03 0,01490114 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 9,885E-03 0,01489181 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 9,885E-03 0,01488249 ! response to ethanol GO:0045471 46 23 0,000 9,885E-03 0,01487318 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 9,885E-03 0,01486388 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 9,885E-03 0,0148546 ! peroxisome organization GO:0007031 37 23 0,000 9,885E-03 0,01484533 ! polysaccharide catabolic process GO:0000272 27 23 0,000 9,885E-03 0,01483607 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 9,885E-03 0,01482682 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 9,885E-03 0,01481758 ! barbed-end actin filament capping GO:0051016 50 23 0,000 9,885E-03 0,01480835 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 9,885E-03 0,01479914 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 9,885E-03 0,01478993 ! regulation of viral reproduction GO:0050792 38 23 0,000 9,885E-03 0,01478074 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 9,885E-03 0,01477156 ! leukotriene metabolic process GO:0006691 42 23 0,000 9,885E-03 0,01476239 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 9,885E-03 0,01475323 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 9,885E-03 0,01474409 ! synaptic vesicle transport GO:0048489 46 23 0,000 9,885E-03 0,01473495 ! fatty acid transport GO:0015908 44 23 0,000 9,885E-03 0,01472583 ! platelet activation GO:0030168 37 23 0,000 9,885E-03 0,01471672 ! regulation of bone mineralization GO:0030500 49 23 0,000 9,885E-03 0,01470761 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 9,885E-03 0,01469852 ! hormone transport GO:0009914 40 23 0,000 9,885E-03 0,01468945 ! cell-cell recognition GO:0009988 25 23 0,000 9,885E-03 0,01468038 ! negative regulation of cytokine production GO:0001818 40 23 0,000 9,885E-03 0,01467132 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 9,885E-03 0,01466228 ! negative regulation of catabolic process GO:0009895 50 23 0,000 9,885E-03 0,01465324 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 9,885E-03 0,01464422 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 9,885E-03 0,01463521 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,01031225 0,01525909 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,01031225 0,01524971 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,01031225 0,01524035 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,01031225 0,01523099 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,01031225 0,01522165 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,01031225 0,01521231 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,01031225 0,01520299 ! vesicle docking GO:0048278 47 24 0,000 0,01031225 0,01519368 ! spinal cord development GO:0021510 47 24 0,000 0,01031225 0,01518438 ! vacuole organization GO:0007033 43 24 0,000 0,01031225 0,0151751 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,01031225 0,01516582 ! digestive system process GO:0022600 39 24 0,000 0,01031225 0,01515656 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,01031225 0,0151473 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,01031225 0,01513806 ! regulation of behavior GO:0050795 43 24 0,000 0,01031225 0,01512883 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,01031225 0,01511961 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,01031225 0,0151104 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,01031225 0,01510121 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,01031225 0,01509202 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,01031225 0,01508285 ! membrane depolarization GO:0051899 39 24 0,000 0,01031225 0,01507368 ! pallium development GO:0021543 49 24 0,000 0,01031225 0,01506453 ! pentose metabolic process GO:0019321 35 24 0,000 0,01031225 0,01505539 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,01031225 0,01504626 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,01031225 0,01503714 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,01031225 0,01502803 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,01031225 0,01501894 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,01031225 0,01500985 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,01031225 0,01500078 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,01031225 0,01499171 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,01031225 0,01498266 ! regulation of amine transport GO:0051952 40 24 0,000 0,01031225 0,01497362 ! protein tetramerization GO:0051262 52 24 0,000 0,01031225 0,01496459 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,01073979 0,01557561 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,01073979 0,01556623 ! myelination GO:0042552 45 25 0,000 0,01073979 0,01555686 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,01073979 0,0155475 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,01073979 0,01553815 ! phototransduction GO:0007602 33 25 0,000 0,01073979 0,01552881 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,01073979 0,01551948 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,01073979 0,01551017 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,01073979 0,01550087 ! sperm motility GO:0030317 31 25 0,000 0,01073979 0,01549157 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,01073979 0,01548229 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,01073979 0,01547302 ! receptor metabolic process GO:0043112 46 25 0,000 0,01073979 0,01546376 ! chromosome condensation GO:0030261 45 25 0,000 0,01073979 0,01545451 ! response to starvation GO:0042594 42 25 0,000 0,01073979 0,01544527 ! osteoblast differentiation GO:0001649 60 25 0,000 0,01073979 0,01543605 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,01073979 0,01542683 ! neural crest cell development GO:0014032 54 25 0,000 0,01073979 0,01541763 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,01073979 0,01540843 ! negative regulation of cell development GO:0010721 73 25 0,000 0,01073979 0,01539925 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,01073979 0,01539008 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,01073979 0,01538092 ! interaction with host GO:0051701 62 25 0,000 0,01073979 0,01537177 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,01073979 0,01536263 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,01073979 0,0153535 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,01073979 0,01534438 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,01073979 0,01533528 ! immunoglobulin production GO:0002377 55 25 0,000 0,01073979 0,01532618 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,01073979 0,0153171 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,01073979 0,01530802 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,01073979 0,01529896 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,01073979 0,01528991 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,01073979 0,01528086 ! telomere organization GO:0032200 43 25 0,000 0,01073979 0,01527183 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,01073979 0,01526281 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,01073979 0,0152538 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,01116716 0,01585144 ! embryonic pattern specification GO:0009880 44 26 0,000 0,01116716 0,01584209 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,01116716 0,01583276 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,01116716 0,01582343 ! initiation of viral infection GO:0019059 57 26 0,000 0,01116716 0,01581412 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,01116716 0,01580482 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,01116716 0,01579553 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,01116716 0,01578625 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,01116716 0,01577698 ! molting cycle process GO:0022404 50 26 0,000 0,01116716 0,01576772 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,01116716 0,01575847 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,01116716 0,01574923 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,01116716 0,01574001 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,01116716 0,01573079 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,01116716 0,01572159 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,01116716 0,01571239 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,01116716 0,01570321 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,01116716 0,01569404 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,01116716 0,01568488 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,01116716 0,01567572 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,01116716 0,01566658 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,01116716 0,01565745 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,01116716 0,01564834 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,01116716 0,01563923 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,01116716 0,01563013 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,01116716 0,01562104 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,01116716 0,01561197 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,01116716 0,0156029 ! blastocyst development GO:0001824 49 26 0,000 0,01116716 0,01559384 ! leukocyte proliferation GO:0070661 52 26 0,000 0,01116716 0,0155848 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,01116716 0,01557576 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,01116716 0,01556674 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,01159436 0,01615288 ! neuron fate commitment GO:0048663 48 27 0,000 0,01159436 0,01614354 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,01159436 0,0161342 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,01159436 0,01612487 ! iron ion transport GO:0006826 59 27 0,000 0,01159436 0,01611556 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,01159436 0,01610625 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,01159436 0,01609696 ! protein amino acid acylation GO:0043543 55 27 0,000 0,01159436 0,01608768 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,01159436 0,0160784 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,01159436 0,01606914 ! fat cell differentiation GO:0045444 50 27 0,000 0,01159436 0,01605989 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,01159436 0,01605065 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,01159436 0,01604142 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,01159436 0,0160322 ! autophagy GO:0006914 41 27 0,000 0,01159436 0,01602299 ! male gonad development GO:0008584 44 27 0,000 0,01159436 0,0160138 ! response to toxin GO:0009636 47 27 0,000 0,01159436 0,01600461 ! primary neural tube formation GO:0014020 51 27 0,000 0,01159436 0,01599543 ! base-excision repair GO:0006284 41 27 0,000 0,01159436 0,01598626 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,01159436 0,01597711 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,01159436 0,01596796 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,01159436 0,01595883 ! glutathione metabolic process GO:0006749 39 27 0,000 0,01159436 0,0159497 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,01159436 0,01594059 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,01159436 0,01593149 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,01159436 0,01592239 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,01159436 0,01591331 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,01202139 0,01649 ! circadian rhythm GO:0007623 50 28 0,000 0,01202139 0,0164806 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,01202139 0,01647122 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,01202139 0,01646184 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,01202139 0,01645248 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,01202139 0,01644313 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,01202139 0,01643378 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,01202139 0,01642445 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,01202139 0,01641513 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,01202139 0,01640582 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,01202139 0,01639652 ! synaptogenesis GO:0007416 42 28 0,000 0,01202139 0,01638723 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,01202139 0,01637795 ! lipid oxidation GO:0034440 43 28 0,000 0,01202139 0,01636868 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,01202139 0,01635942 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,01202139 0,01635018 ! translational initiation GO:0006413 65 29 0,000 0,01244825 0,01692118 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,01244825 0,01691162 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,01244825 0,01690208 ! regulation of pH GO:0006885 43 29 0,000 0,01244825 0,01689254 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,01244825 0,01688302 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,01244825 0,01687351 ! catechol metabolic process GO:0009712 54 29 0,000 0,01244825 0,01686401 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,01244825 0,01685452 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,01244825 0,01684504 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,01244825 0,01683557 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,01244825 0,01682611 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,01244825 0,01681666 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,01244825 0,01680723 ! cell fate determination GO:0001709 60 29 0,000 0,01244825 0,0167978 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,01244825 0,01678839 ! detection of light stimulus GO:0009583 38 29 0,000 0,01244825 0,01677898 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,01244825 0,01676959 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,01244825 0,0167602 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,01244825 0,01675083 ! tissue homeostasis GO:0001894 48 29 0,000 0,01244825 0,01674146 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,01244825 0,01673211 ! phenol metabolic process GO:0018958 55 30 0,000 0,01287493 0,01729597 ! zinc ion transport GO:0006829 45 30 0,000 0,01287493 0,01728632 ! membrane docking GO:0022406 61 30 0,000 0,01287493 0,01727668 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,01287493 0,01726705 ! cell junction assembly GO:0034329 78 30 0,000 0,01287493 0,01725743 ! regulation of innate immune response GO:0045088 51 30 0,000 0,01287493 0,01724782 ! acute-phase response GO:0006953 49 30 0,000 0,01287493 0,01723823 ! myofibril assembly GO:0030239 47 30 0,000 0,01287493 0,01722864 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,01287493 0,01721906 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,01287493 0,01720949 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,01287493 0,01719994 ! phospholipid transport GO:0015914 51 30 0,000 0,01287493 0,01719039 ! ensheathment of neurons GO:0007272 57 30 0,000 0,01287493 0,01718086 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,01287493 0,01717134 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,01287493 0,01716182 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,01287493 0,01715232 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,01287493 0,01714283 ! eye morphogenesis GO:0048592 60 30 0,000 0,01287493 0,01713335 ! regulation of B cell activation GO:0050864 50 30 0,000 0,01287493 0,01712388 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,01330145 0,01768138 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,01330145 0,01767161 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,01330145 0,01766186 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,01330145 0,01765212 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,01330145 0,01764239 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,01330145 0,01763267 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,01330145 0,01762296 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,01330145 0,01761326 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,01330145 0,01760357 ! ovulation cycle process GO:0022602 49 31 0,000 0,01330145 0,01759389 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,01330145 0,01758423 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,01330145 0,01757457 ! peptide transport GO:0015833 55 31 0,000 0,01330145 0,01756492 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,01330145 0,01755529 ! iron ion homeostasis GO:0055072 54 31 0,000 0,01330145 0,01754566 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,01330145 0,01753605 ! mesoderm formation GO:0001707 69 31 0,000 0,01330145 0,01752645 ! natural killer cell activation GO:0030101 45 31 0,000 0,01330145 0,01751685 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,01330145 0,01750727 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,01330145 0,0174977 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,01330145 0,01748814 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,01330145 0,01747859 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,01330145 0,01746905 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,0137278 0,01801914 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,0137278 0,01800931 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,0137278 0,0179995 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,0137278 0,0179897 ! cholesterol transport GO:0030301 56 32 0,000 0,0137278 0,0179799 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,0137278 0,01797012 ! spliceosome assembly GO:0000245 67 32 0,000 0,0137278 0,01796035 ! spindle organization GO:0007051 46 32 0,000 0,0137278 0,01795059 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,0137278 0,01794084 ! metanephros development GO:0001656 74 32 0,000 0,0137278 0,0179311 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,0137278 0,01792137 ! response to ionizing radiation GO:0010212 65 32 0,000 0,0137278 0,01791165 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,0137278 0,01790194 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,0137278 0,01789224 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,0137278 0,01788256 ! muscle cell development GO:0055001 49 32 0,000 0,0137278 0,01787288 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,0137278 0,01786321 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,0137278 0,01785356 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,0137278 0,01784391 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,0137278 0,01783428 ! ovulation cycle GO:0042698 51 32 0,000 0,0137278 0,01782465 ! peripheral nervous system development GO:0007422 64 32 0,000 0,0137278 0,01781504 ! BMP signaling pathway GO:0030509 64 32 0,000 0,0137278 0,01780544 ! hindbrain development GO:0030902 61 32 0,000 0,0137278 0,01779584 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,0137278 0,01778626 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,0137278 0,01777669 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,0137278 0,01776712 ! gene silencing GO:0016458 65 32 0,000 0,0137278 0,01775757 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,01415398 0,01829901 ! post-embryonic development GO:0009791 69 33 0,000 0,01415398 0,01828919 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,01415398 0,01827937 ! protein targeting to membrane GO:0006612 68 33 0,000 0,01415398 0,01826956 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,01415398 0,01825977 ! ceramide metabolic process GO:0006672 64 33 0,000 0,01415398 0,01824998 ! formation of primary germ layer GO:0001704 72 33 0,000 0,01415398 0,01824021 ! cell fate specification GO:0001708 52 33 0,000 0,01415398 0,01823044 ! sterol transport GO:0015918 57 33 0,000 0,01415398 0,01822069 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,01415398 0,01821094 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,01415398 0,01820121 ! adult locomotory behavior GO:0008344 59 33 0,000 0,01415398 0,01819149 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,01415398 0,01818177 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,01415398 0,01817207 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,01457998 0,01870903 ! glial cell differentiation GO:0010001 63 34 0,000 0,01457998 0,01869906 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,01457998 0,0186891 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,01457998 0,01867915 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,01457998 0,01866921 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,01457998 0,01865928 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,01457998 0,01864936 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,01457998 0,01863945 ! mismatch repair GO:0006298 46 34 0,000 0,01457998 0,01862955 ! spermatid development GO:0007286 63 34 0,000 0,01457998 0,01861966 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,01457998 0,01860978 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,01457998 0,01859991 ! placenta development GO:0001890 53 34 0,000 0,01457998 0,01859006 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,01457998 0,01858021 ! regulation of muscle development GO:0048634 70 35 0,000 0,01500582 0,01911276 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,01500582 0,01910265 ! negative regulation of secretion GO:0051048 63 35 0,000 0,01500582 0,01909254 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,01500582 0,01908245 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,01500582 0,01907237 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,01500582 0,0190623 ! odontogenesis GO:0042476 66 35 0,000 0,01500582 0,01905224 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,01500582 0,0190422 ! female gonad development GO:0008585 58 35 0,000 0,01500582 0,01903216 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,01500582 0,01902213 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,01500582 0,01901211 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,01500582 0,01900211 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,01500582 0,01899211 ! cytokine production GO:0001816 59 35 0,000 0,01500582 0,01898213 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,01500582 0,01897215 ! neural tube formation GO:0001841 67 35 0,000 0,01500582 0,01896219 ! vesicle localization GO:0051648 64 35 0,000 0,01500582 0,01895223 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,01543149 0,01947962 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,01543149 0,01946941 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,01543149 0,0194592 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,01543149 0,01944901 ! cell junction organization GO:0034330 86 36 0,000 0,01543149 0,01943883 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,01543149 0,01942865 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,01543149 0,01941849 ! positive regulation of cell development GO:0010720 80 36 0,000 0,01543149 0,01940834 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,01543149 0,0193982 ! regulation of proteolysis GO:0030162 72 36 0,000 0,01543149 0,01938807 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,01543149 0,01937795 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,01543149 0,01936784 ! aerobic respiration GO:0009060 55 36 0,000 0,01543149 0,01935775 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,01543149 0,01934766 ! embryonic organ development GO:0048568 57 36 0,000 0,01543149 0,01933758 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,01543149 0,01932752 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,01543149 0,01931746 ! RNA export from nucleus GO:0006405 56 37 0,000 0,01585698 0,01983978 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,01585698 0,01982947 ! meiosis I GO:0007127 65 37 0,000 0,01585698 0,01981917 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,01585698 0,01980888 ! sister chromatid segregation GO:0000819 58 37 0,000 0,01585698 0,0197986 ! actomyosin structure organization GO:0031032 62 37 0,000 0,01585698 0,01978833 ! organic anion transport GO:0015711 68 37 0,000 0,01585698 0,01977807 ! tissue remodeling GO:0048771 76 37 0,000 0,01585698 0,01976783 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,01585698 0,01975759 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,01585698 0,01974736 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,01585698 0,01973715 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,01585698 0,01972694 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,01585698 0,01971675 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,01585698 0,01970656 ! glycogen metabolic process GO:0005977 61 37 0,000 0,01585698 0,01969639 ! pigment metabolic process GO:0042440 80 37 0,000 0,01585698 0,01968623 ! spermatid differentiation GO:0048515 66 37 0,000 0,01585698 0,01967607 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,01585698 0,01966593 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,01628231 0,02018302 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,01628231 0,02017263 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,01628231 0,02016225 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,01628231 0,02015187 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,01628231 0,02014151 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,01628231 0,02013116 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,01628231 0,02012082 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,01628231 0,02011049 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,01628231 0,02010018 ! lipid homeostasis GO:0055088 67 38 0,000 0,01628231 0,02008987 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,01628231 0,02007957 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,01628231 0,02006928 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,01628231 0,02005901 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,01628231 0,02004874 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,01628231 0,02003849 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,01628231 0,02002824 ! glucan metabolic process GO:0044042 62 38 0,000 0,01628231 0,02001801 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,01670747 0,02053022 ! mammary gland development GO:0030879 86 39 0,000 0,01670747 0,02051974 ! learning GO:0007612 77 39 0,000 0,01670747 0,02050927 ! ear morphogenesis GO:0042471 60 39 0,000 0,01670747 0,02049881 ! organic ether metabolic process GO:0018904 55 39 0,000 0,01670747 0,02048837 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,01670747 0,02047793 ! segmentation GO:0035282 67 39 0,000 0,01670747 0,0204675 ! ion transmembrane transport GO:0034220 66 39 0,000 0,01670747 0,02045709 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,01670747 0,02044668 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,01670747 0,02043629 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,01670747 0,0204259 ! RNA modification GO:0009451 57 39 0,000 0,01670747 0,02041553 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,01670747 0,02040516 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,01713246 0,02091359 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,01713246 0,02090299 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,01713246 0,0208924 ! feeding behavior GO:0007631 59 40 0,000 0,01713246 0,02088181 ! negative regulation of binding GO:0051100 72 40 0,000 0,01713246 0,02087124 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,01713246 0,02086068 ! mesenchymal cell development GO:0014031 87 40 0,000 0,01713246 0,02085012 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,01713246 0,02083958 ! maintenance of protein location GO:0045185 91 40 0,000 0,01713246 0,02082905 ! cytokinesis GO:0000910 72 40 0,000 0,01713246 0,02081853 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,01755728 0,02132398 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,01755728 0,02131322 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,01755728 0,02130248 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,01755728 0,02129174 ! gliogenesis GO:0042063 88 41 0,000 0,01755728 0,02128101 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,01755728 0,0212703 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,01755728 0,02125959 ! T cell differentiation GO:0030217 81 41 0,000 0,01755728 0,0212489 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,01755728 0,02123822 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,01755728 0,02122754 ! female gamete generation GO:0007292 61 41 0,000 0,01755728 0,02121688 ! polyol metabolic process GO:0019751 66 41 0,000 0,01755728 0,02120623 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,01755728 0,02119559 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,01798193 0,02169735 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,01798193 0,02168647 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,01798193 0,02167561 ! regulation of tube size GO:0035150 71 42 0,000 0,01798193 0,02166476 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,01798193 0,02165391 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,01798193 0,02164308 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,01798193 0,02163226 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,01798193 0,02162145 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,01798193 0,02161065 ! neuron migration GO:0001764 79 42 0,000 0,01798193 0,02159986 ! regulation of protein secretion GO:0050708 71 42 0,000 0,01798193 0,02158908 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,01798193 0,02157831 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,01840641 0,02207668 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,01840641 0,02206568 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,01840641 0,02205469 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,01840641 0,02204371 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,01840641 0,02203274 ! glucose transport GO:0015758 65 43 0,000 0,01840641 0,02202179 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,01840641 0,02201084 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,01840641 0,02199991 ! neural tube development GO:0021915 77 43 0,000 0,01840641 0,02198898 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,01840641 0,02197807 ! striated muscle contraction GO:0006941 77 43 0,000 0,01840641 0,02196717 ! phagocytosis GO:0006909 90 43 0,000 0,01840641 0,02195628 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,01840641 0,0219454 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,01883072 0,02244017 ! hexose transport GO:0008645 67 44 0,000 0,01883072 0,02242906 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,01883072 0,02241796 ! male sex differentiation GO:0046661 76 44 0,000 0,01883072 0,02240688 ! double-strand break repair GO:0006302 81 44 0,000 0,01883072 0,0223958 ! biopolymer methylation GO:0043414 84 44 0,000 0,01883072 0,02238474 ! B cell differentiation GO:0030183 107 44 0,000 0,01883072 0,02237368 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,01883072 0,02236264 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,01883072 0,02235161 ! developmental growth GO:0048589 82 44 0,000 0,01883072 0,02234059 ! maintenance of location in cell GO:0051651 97 44 0,000 0,01883072 0,02232957 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,01925486 0,02282128 ! glycolysis GO:0006096 65 45 0,000 0,01925486 0,02281004 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,01925486 0,02279881 ! leukocyte migration GO:0050900 68 45 0,000 0,01925486 0,0227876 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,01925486 0,0227764 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,01925486 0,0227652 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,01925486 0,02275402 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,01925486 0,02274285 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,01925486 0,02273169 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,01925486 0,02272054 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,01925486 0,02270941 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,01925486 0,02269828 ! cell growth GO:0016049 84 45 0,000 0,01925486 0,02268716 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,01967883 0,02317536 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,01967883 0,02316402 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,01967883 0,0231527 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,01967883 0,02314138 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,01967883 0,02313008 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,01967883 0,02311878 ! pigmentation GO:0043473 100 46 0,000 0,01967883 0,0231075 ! response to insulin stimulus GO:0032868 95 46 0,000 0,01967883 0,02309623 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,01967883 0,02308497 ! positive regulation of defense response GO:0031349 76 47 0,000 0,02010263 0,02357063 ! response to calcium ion GO:0051592 81 47 0,000 0,02010263 0,02355915 ! endosome transport GO:0016197 108 47 0,000 0,02010263 0,02354768 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,02010263 0,02353622 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,02010263 0,02352477 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,02010263 0,02351334 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,02010263 0,02350191 ! JNK cascade GO:0007254 91 47 0,000 0,02010263 0,0234905 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,02010263 0,0234791 ! methylation GO:0032259 90 47 0,000 0,02010263 0,0234677 ! protein homooligomerization GO:0051260 76 47 0,000 0,02010263 0,02345632 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,02052627 0,02393902 ! mitochondrial transport GO:0006839 82 48 0,000 0,02052627 0,02392742 ! Notch signaling pathway GO:0007219 96 48 0,000 0,02052627 0,02391584 ! cellular component disassembly GO:0022411 86 48 0,000 0,02052627 0,02390426 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,02052627 0,02389269 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,02052627 0,02388114 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,02052627 0,0238696 ! activation of caspase activity GO:0006919 84 48 0,000 0,02052627 0,02385807 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,02052627 0,02384655 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,02052627 0,02383504 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,02052627 0,02382354 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,02052627 0,02381205 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,02094973 0,02429159 ! regulation of action potential GO:0001508 95 49 0,000 0,02094973 0,02427989 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,02094973 0,0242682 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,02094973 0,02425652 ! regulation of ion transport GO:0043269 77 49 0,000 0,02094973 0,02424486 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,02094973 0,0242332 ! peptide metabolic process GO:0006518 76 49 0,000 0,02094973 0,02422155 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,02094973 0,02420992 ! endocrine system development GO:0035270 104 49 0,000 0,02094973 0,0241983 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,02094973 0,02418669 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,02094973 0,02417509 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,02094973 0,0241635 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,02094973 0,02415192 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,02137303 0,02462812 ! neuromuscular process GO:0050905 99 50 0,000 0,02137303 0,02461633 ! regulation of ossification GO:0030278 117 50 0,000 0,02137303 0,02460455 ! inner ear development GO:0048839 79 50 0,000 0,02137303 0,02459278 ! histone modification GO:0016570 91 50 0,000 0,02137303 0,02458103 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,02137303 0,02456928 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,02137303 0,02455755 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,02137303 0,02454583 ! positive regulation of binding GO:0051099 78 51 0,000 0,02179615 0,02501982 ! viral infectious cycle GO:0019058 99 51 0,000 0,02179615 0,02500789 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,02179615 0,02499597 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,02179615 0,02498406 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,02179615 0,02497217 ! excretion GO:0007588 83 51 0,000 0,02179615 0,02496028 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,02179615 0,02494841 ! chromatin remodeling GO:0006338 109 51 0,000 0,02179615 0,02493654 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,02179615 0,02492469 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,02179615 0,02491285 ! vesicle organization GO:0016050 107 51 0,000 0,02179615 0,02490102 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,02179615 0,0248892 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,02179615 0,02487739 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,02179615 0,0248656 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,02221911 0,02533611 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,02221911 0,0253241 ! membrane fusion GO:0006944 110 52 0,000 0,02221911 0,02531211 ! positive regulation of growth GO:0045927 90 52 0,000 0,02221911 0,02530013 ! covalent chromatin modification GO:0016569 101 52 0,000 0,02221911 0,02528817 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,02221911 0,02527621 ! amino acid activation GO:0043038 92 52 0,000 0,02221911 0,02526426 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,02221911 0,02525233 ! synapse organization GO:0050808 85 52 0,000 0,02221911 0,02524041 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,0226419 0,02570855 ! RNA catabolic process GO:0006401 93 53 0,000 0,0226419 0,02569642 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,0226419 0,02568431 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,0226419 0,0256722 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,0226419 0,02566011 ! cell maturation GO:0048469 100 53 0,000 0,0226419 0,02564803 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,0226419 0,02563596 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,0226419 0,0256239 ! response to UV GO:0009411 104 53 0,000 0,0226419 0,02561185 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,02306452 0,02607765 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,02306452 0,0260654 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,02306452 0,02605316 ! cell recognition GO:0008037 85 54 0,000 0,02306452 0,02604094 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,02306452 0,02602872 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,02306452 0,02601652 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,02306452 0,02600433 ! chloride transport GO:0006821 90 55 0,000 0,02348697 0,02646822 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,02348697 0,02645583 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,02348697 0,02644345 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,02348697 0,02643108 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,02348697 0,02641873 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,02348697 0,02640638 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,02348697 0,02639405 ! aging GO:0007568 103 55 0,000 0,02348697 0,02638173 ! gastrulation GO:0007369 112 55 0,000 0,02348697 0,02636942 ! heart morphogenesis GO:0003007 97 55 0,000 0,02348697 0,02635712 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,02348697 0,02634483 ! RNA elongation GO:0006354 79 55 0,000 0,02348697 0,02633255 ! nuclear export GO:0051168 97 55 0,000 0,02348697 0,02632029 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,02348697 0,02630803 ! regulation of actin filament length GO:0030832 105 56 0,000 0,02390926 0,02676858 ! sensory perception of smell GO:0007608 80 56 0,000 0,02390926 0,02675613 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,02390926 0,02674369 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,02390926 0,02673126 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,02390926 0,02671884 ! regulation of DNA replication GO:0006275 101 56 0,000 0,02390926 0,02670644 ! proton transport GO:0015992 94 56 0,000 0,02390926 0,02669405 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,02390926 0,02668167 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 0,000 0,02433137 0,02714014 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,02433137 0,02712756 ! muscle fiber development GO:0048747 112 57 0,000 0,02433137 0,027115 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,02433137 0,02710244 ! lipid modification GO:0030258 97 57 0,000 0,02433137 0,0270899 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,02433137 0,02707737 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,02433137 0,02706485 ! maintenance of location GO:0051235 118 57 0,000 0,02433137 0,02705235 ! hydrogen transport GO:0006818 97 58 0,000 0,02475332 0,02750877 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,02475332 0,02749607 ! regulation of endocytosis GO:0030100 91 58 0,000 0,02475332 0,02748338 ! adult behavior GO:0030534 99 58 0,000 0,02475332 0,0274707 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,02475332 0,02745804 ! positive regulation of secretion GO:0051047 95 59 0,000 0,02517509 0,02791303 ! regulation of cellular component size GO:0032535 109 59 0,000 0,02517509 0,02790017 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,02517509 0,02788733 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,02517509 0,02787449 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,02517509 0,02786167 ! DNA catabolic process GO:0006308 86 59 0,000 0,02517509 0,02784886 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,02517509 0,02783606 ! establishment of organelle localization GO:0051656 109 59 0,000 0,02517509 0,02782328 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,0255967 0,02827625 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,0255967 0,02826327 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,0255967 0,02825031 ! regulation of heart contraction GO:0008016 110 60 0,000 0,0255967 0,02823735 ! camera-type eye development GO:0043010 116 60 0,000 0,0255967 0,02822441 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,0255967 0,02821148 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,0255967 0,02819857 ! kidney development GO:0001822 122 60 0,000 0,0255967 0,02818566 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,02601814 0,02863662 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,02601814 0,02862353 ! mesoderm development GO:0007498 119 61 0,000 0,02601814 0,02861044 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,02601814 0,02859737 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,02601814 0,02858432 ! ear development GO:0043583 103 62 0,000 0,02643942 0,02903388 ! viral reproductive process GO:0022415 126 62 0,000 0,02643942 0,02902064 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,02643942 0,0290074 ! gonad development GO:0008406 98 62 0,000 0,02643942 0,02899418 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,02643942 0,02898097 ! regulation of mitosis GO:0007088 105 63 0,000 0,02686052 0,02942915 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,02686052 0,02941575 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,02686052 0,02940237 ! detection of external stimulus GO:0009581 91 63 0,000 0,02686052 0,029389 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,02686052 0,02937564 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,02686052 0,02936229 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,02728146 0,02980889 ! cell redox homeostasis GO:0045454 102 64 0,000 0,02728146 0,02979536 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,02728146 0,02978184 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,02728146 0,02976834 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,02728146 0,02975484 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,02728146 0,02974136 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,02770222 0,03018639 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,02770222 0,03017273 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,02770222 0,03015907 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,02770222 0,03014543 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,02770222 0,0301318 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,02812282 0,03057547 ! actin filament organization GO:0007015 148 66 0,000 0,02812282 0,03056166 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,02812282 0,03054786 ! extracellular matrix organization GO:0030198 133 66 0,000 0,02812282 0,03053408 ! secondary metabolic process GO:0019748 116 66 0,000 0,02812282 0,0305203 ! developmental maturation GO:0021700 116 66 0,000 0,02812282 0,03050654 ! cell projection assembly GO:0030031 120 66 0,000 0,02812282 0,0304928 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,02854326 0,03093472 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,02854326 0,03092079 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,02854326 0,03090687 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,02854326 0,03089297 ! activation of MAPK activity GO:0000187 115 67 0,000 0,02854326 0,03087908 ! lung development GO:0030324 144 67 0,000 0,02854326 0,0308652 ! chromosome segregation GO:0007059 113 67 0,000 0,02854326 0,03085134 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,02854326 0,03083748 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,02854326 0,03082364 ! hexose catabolic process GO:0019320 104 67 0,000 0,02854326 0,03080981 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,02854326 0,030796 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,02854326 0,03078219 ! adaptive immune response GO:0002250 119 67 0,000 0,02854326 0,0307684 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,02854326 0,03075462 ! amino acid transport GO:0006865 125 68 0,000 0,02896352 0,03119348 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,02896352 0,03117952 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,02896352 0,03116558 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,02896352 0,03115164 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,02896352 0,03113773 ! viral reproduction GO:0016032 134 68 0,000 0,02896352 0,03112382 ! regulation of lipase activity GO:0060191 130 68 0,000 0,02896352 0,03110992 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,02896352 0,03109604 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,02896352 0,03108217 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,02938362 0,03151894 ! negative regulation of cell size GO:0045792 134 69 0,000 0,02938362 0,03150489 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,02938362 0,03149086 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,02938362 0,03147684 ! urogenital system development GO:0001655 137 69 0,000 0,02938362 0,03146283 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,02938362 0,03144884 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,02938362 0,03143485 ! antigen processing and presentation GO:0019882 104 69 0,000 0,02938362 0,03142088 ! appendage morphogenesis GO:0035107 135 70 0,000 0,02980355 0,03185577 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,02980355 0,03184162 ! amine catabolic process GO:0009310 117 71 0,000 0,03022331 0,03227575 ! reproductive structure development GO:0048608 113 71 0,000 0,03022331 0,03226143 ! appendage development GO:0048736 136 71 0,000 0,03022331 0,03224713 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,03022331 0,03223283 ! B cell activation GO:0042113 160 71 0,000 0,03022331 0,03221855 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,03022331 0,03220428 ! regulation of immune effector process GO:0002697 137 71 0,000 0,03022331 0,03219003 ! acute inflammatory response GO:0002526 113 72 0,000 0,0306429 0,03262248 ! regulation of caspase activity GO:0043281 122 72 0,000 0,0306429 0,03260806 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,0306429 0,03259364 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,0306429 0,03257924 ! carbohydrate transport GO:0008643 110 72 0,000 0,0306429 0,03256485 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,0306429 0,03255047 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,0306429 0,03253611 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,0306429 0,03252175 ! respiratory system development GO:0060541 153 72 0,000 0,0306429 0,03250741 ! learning or memory GO:0007611 147 73 0,000 0,03106232 0,03293784 ! regulation of blood pressure GO:0008217 125 73 0,000 0,03106232 0,03292333 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,03106232 0,03290883 ! axon guidance GO:0007411 139 73 0,000 0,03106232 0,03289435 ! fertilization GO:0009566 90 73 0,000 0,03106232 0,03287987 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,03148158 0,03330901 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,03148158 0,03329437 ! neurotransmitter transport GO:0006836 123 74 0,000 0,03148158 0,03327974 ! meiosis GO:0007126 121 74 0,000 0,03148158 0,03326512 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,03148158 0,03325052 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,03148158 0,03323593 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,03148158 0,03322135 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,03148158 0,03320679 ! eye development GO:0001654 143 74 0,000 0,03148158 0,03319224 ! organelle localization GO:0051640 136 74 0,000 0,03148158 0,0331777 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,03190067 0,03360465 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,03190067 0,03358994 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,03190067 0,03357525 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,03190067 0,03356057 ! meiotic cell cycle GO:0051321 122 75 0,000 0,03190067 0,0335459 ! rhythmic process GO:0048511 128 75 0,000 0,03190067 0,03353125 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,03190067 0,0335166 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,0323196 0,03394192 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,0323196 0,03392712 ! defense response to bacterium GO:0042742 89 76 0,000 0,0323196 0,03391232 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,0323196 0,03389754 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,0323196 0,03388277 ! regulation of catabolic process GO:0009894 161 76 0,000 0,0323196 0,03386801 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,03273835 0,03429189 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,03273835 0,03427697 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,03273835 0,03426206 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,03273835 0,03424716 ! blood coagulation GO:0007596 146 78 0,000 0,03315694 0,03466997 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,03315694 0,03465491 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,03315694 0,03463986 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,03315694 0,03462483 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,03357536 0,03504656 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,03357536 0,03503136 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,03357536 0,03501618 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,03357536 0,03500101 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,03357536 0,03498585 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,03357536 0,0349707 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,03357536 0,03495557 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,03399362 0,03537571 ! response to metal ion GO:0010038 140 80 0,000 0,03399362 0,03536042 ! muscle cell differentiation GO:0042692 159 80 0,000 0,03399362 0,03534513 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,03399362 0,03532987 ! protein import into nucleus GO:0006606 158 80 0,000 0,03399362 0,03531461 ! inorganic anion transport GO:0015698 138 80 0,000 0,03399362 0,03529937 ! T cell activation GO:0042110 168 81 0,000 0,0344117 0,0357181 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,0344117 0,0357027 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 0,000 0,0344117 0,03568731 ! digestion GO:0007586 112 81 0,000 0,0344117 0,03567193 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,0344117 0,03565657 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,0344117 0,03564122 ! nuclear import GO:0051170 161 81 0,000 0,0344117 0,03562589 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,0344117 0,03561056 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,03482962 0,03602755 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,03482962 0,03601207 ! response to drug GO:0042493 143 82 0,000 0,03482962 0,0359966 ! response to nutrient GO:0007584 125 82 0,000 0,03482962 0,03598114 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,03482962 0,0359657 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,03482962 0,03595027 ! response to oxygen levels GO:0070482 176 83 0,000 0,03524738 0,03636586 ! regulation of lyase activity GO:0051339 160 83 0,000 0,03524738 0,03635027 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,03566496 0,03676517 ! hemostasis GO:0007599 158 84 0,000 0,03566496 0,03674942 ! negative regulation of transport GO:0051051 153 84 0,000 0,03566496 0,03673369 ! negative regulation of growth GO:0045926 155 84 0,000 0,03566496 0,03671797 ! regulation of ligase activity GO:0051340 142 84 0,000 0,03566496 0,03670227 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,03566496 0,03668658 ! nucleosome assembly GO:0006334 122 85 0,000 0,03608238 0,03710009 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,03608238 0,03708424 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,03608238 0,03706841 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,03649964 0,03748106 ! response to inorganic substance GO:0010035 153 86 0,000 0,03649964 0,03746507 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,03649964 0,03744909 ! chromatin assembly GO:0031497 124 86 0,000 0,03649964 0,03743313 ! tube morphogenesis GO:0035239 176 86 0,000 0,03649964 0,03741718 ! mitochondrion organization GO:0007005 148 86 0,000 0,03649964 0,03740124 ! alcohol catabolic process GO:0046164 130 86 0,000 0,03649964 0,03738532 ! amine transport GO:0015837 155 86 0,000 0,03649964 0,03736941 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,03691672 0,03778036 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,03691672 0,0377643 ! protein localization in nucleus GO:0034504 176 87 0,000 0,03691672 0,03774825 ! regulation of protein transport GO:0051223 154 87 0,000 0,03691672 0,03773221 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,03733364 0,03814214 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,03733364 0,03812595 ! regulation of DNA binding GO:0051101 155 88 0,000 0,03733364 0,03810977 ! gland development GO:0048732 206 88 0,000 0,03733364 0,03809361 ! regulation of neurological system process GO:0031644 148 88 0,000 0,03733364 0,03807746 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,03733364 0,03806133 ! cellular defense response GO:0006968 114 89 0,000 0,03775039 0,0384699 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,03775039 0,03845362 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,03775039 0,03843734 ! ossification GO:0001503 188 90 0,000 0,03816698 0,03884507 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,03816698 0,03882865 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,03816698 0,03881224 ! sex differentiation GO:0007548 145 90 0,000 0,03816698 0,03879584 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,03816698 0,03877946 ! bone development GO:0060348 189 91 0,000 0,0385834 0,03918601 ! sterol metabolic process GO:0016125 152 91 0,000 0,0385834 0,03916948 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,0385834 0,03915296 ! regulation of defense response GO:0031347 149 92 0,000 0,03899965 0,03955867 ! nucleosome organization GO:0034728 138 92 0,000 0,03899965 0,039542 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,03899965 0,03952534 ! vitamin metabolic process GO:0006766 139 92 0,000 0,03899965 0,0395087 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,03941574 0,03991341 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,03941574 0,03989662 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,03941574 0,03987984 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,03941574 0,03986308 ! regulation of membrane potential GO:0042391 164 93 0,000 0,03941574 0,03984633 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,03941574 0,0398296 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,03983166 0,04023299 ! female pregnancy GO:0007565 164 94 0,000 0,03983166 0,0402161 ! transcription initiation GO:0006352 153 94 0,000 0,03983166 0,04019923 ! regulation of T cell activation GO:0050863 158 94 0,000 0,03983166 0,04018238 ! interphase of mitotic cell cycle GO:0051329 209 95 0,000 0,04024741 0,04058478 ! forebrain development GO:0030900 188 95 0,000 0,04024741 0,04056777 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,04024741 0,04055079 ! leukocyte differentiation GO:0002521 202 96 0,000 0,040663 0,04095236 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,040663 0,04093522 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,040663 0,0409181 ! positive regulation of immune response GO:0050778 156 96 0,000 0,040663 0,04090099 ! detection of stimulus GO:0051606 151 96 0,000 0,040663 0,0408839 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,04107842 0,04128433 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,04107842 0,04126709 ! protein ubiquitination GO:0016567 217 97 0,000 0,04107842 0,04124987 ! hormone metabolic process GO:0042445 157 97 0,000 0,04107842 0,04123266 ! regulation of protein localization GO:0032880 176 97 0,000 0,04107842 0,04121547 ! response to virus GO:0009615 160 98 0,000 0,04149368 0,04161475 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,04149368 0,04159741 ! interphase GO:0051325 213 98 0,000 0,04149368 0,04158009 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,04149368 0,04156278 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,04190877 0,04196109 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,04190877 0,04194363 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,04190877 0,04192619 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 0,000 0,04232369 0,04232369