pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/10542-0-real-Loi_GPL570-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of caspase activity GO:0043154 23 14 3,000 1,895E-10 4,63E-07 ! negative regulation of peptidase activity GO:0010466 28 17 3,000 4,5E-10 5,497E-07 ! negative regulation of hydrolase activity GO:0051346 66 36 3,000 1,104E-08 8,989E-06 ! regulation of caspase activity GO:0043281 136 74 3,000 2,118E-07 1,293E-04 ! regulation of endopeptidase activity GO:0052548 141 77 3,000 2,487E-07 1,215E-04 ! regulation of peptidase activity GO:0052547 150 82 3,000 3,207E-07 1,306E-04 ! viral genome replication GO:0019079 44 23 2,000 5,393E-07 1,882E-04 ! glycolysis GO:0006096 71 46 2,000 4,573E-06 1,397E-03 ! negative regulation of protein ubiquitination GO:0031397 10 5 1,000 4,743E-06 1,288E-03 ! viral infectious cycle GO:0019058 104 51 2,000 6,259E-06 1,529E-03 ! activation of Ras GTPase activity GO:0032856 13 6 1,000 7,112E-06 1,579E-03 GO:0032862|activation of Rho GTPase activity, ! glucose catabolic process GO:0006007 88 56 2,000 8,312E-06 1,692E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 8,77E-06 1,648E-03 ! viral reproductive process GO:0022415 132 62 2,000 1,131E-05 1,974E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 1,326E-05 2,16E-03 ! regulation of focal adhesion formation GO:0051893 23 8 1,000 1,326E-05 2,025E-03 ! hexose catabolic process GO:0019320 113 68 2,000 1,494E-05 2,148E-03 ! viral reproduction GO:0016032 142 68 2,000 1,494E-05 2,028E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 2,000 1,494E-05 1,922E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 2,000 1,562E-05 1,908E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 1,705E-05 1,983E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 2,000 1,775E-05 1,971E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 2,000 1,775E-05 1,886E-03 ! regulation of phosphatase activity GO:0010921 28 10 1,000 2,13E-05 2,168E-03 ! regulation of stress fiber formation GO:0051492 34 10 1,000 2,13E-05 2,081E-03 ! positive regulation of ligase activity GO:0051351 130 77 2,000 2,172E-05 2,041E-03 ! monosaccharide catabolic process GO:0046365 125 77 2,000 2,172E-05 1,965E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 2,346E-05 2,047E-03 ! keratinocyte proliferation GO:0043616 19 11 1,000 2,602E-05 2,192E-03 ! positive regulation of Rho GTPase activity GO:0032321 31 11 1,000 2,602E-05 2,119E-03 ! regulation of actin filament bundle formation GO:0032231 37 11 1,000 2,602E-05 2,051E-03 ! regulation of embryonic development GO:0045995 35 11 1,000 2,602E-05 1,986E-03 ! regulation of ligase activity GO:0051340 147 84 2,000 2,82E-05 2,088E-03 ! alcohol catabolic process GO:0046164 142 87 2,000 3,133E-05 2,251E-03 ! positive regulation of cell growth GO:0030307 24 13 1,000 3,687E-05 2,573E-03 ! regulation of cell adhesion GO:0030155 241 92 2,000 3,703E-05 2,513E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 2,000 3,825E-05 2,526E-03 GO:0010498|proteasomal protein catabolic process, ! positive regulation of Ras GTPase activity GO:0032320 42 14 1,000 4,3E-05 2,764E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 4,3E-05 2,693E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 4,473E-05 2,732E-03 ! positive regulation of GTPase activity GO:0043547 43 15 1,000 4,959E-05 2,955E-03 ! regulation of protein ubiquitination GO:0031396 28 16 1,000 5,665E-05 3,295E-03 ! positive regulation of cell size GO:0045793 29 16 1,000 5,665E-05 3,218E-03 ! regulation of dephosphorylation GO:0035303 43 16 1,000 5,665E-05 3,145E-03 ! skin development GO:0043588 42 20 1,000 8,954E-05 4,861E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 8,954E-05 4,755E-03 ! cellular response to unfolded protein GO:0034620 35 20 1,000 8,954E-05 4,654E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! negative regulation of translation GO:0017148 32 20 1,000 8,954E-05 4,557E-03 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 1,191E-04 5,937E-03 GO:0010810|regulation of cell-substrate adhesion, ! regulation of Rho GTPase activity GO:0032319 56 23 1,000 1,191E-04 5,818E-03 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 1,298E-04 6,22E-03 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 1,411E-04 6,628E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 1,411E-04 6,503E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 1,528E-04 6,911E-03 ! negative regulation of protein modification process GO:0031400 66 28 1,000 1,775E-04 7,885E-03 ! fat cell differentiation GO:0045444 57 28 1,000 1,775E-04 7,744E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 1,906E-04 8,169E-03 ! RNA export from nucleus GO:0006405 61 41 1,000 3,829E-04 0,01613007 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 4,615E-04 0,01911106 ! keratinocyte differentiation GO:0030216 81 45 1,000 4,615E-04 0,01879255 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 4,823E-04 0,01931635 ! response to insulin stimulus GO:0032868 98 47 1,000 5,035E-04 0,0198409 ! positive regulation of cell cycle GO:0045787 96 48 1,000 5,252E-04 0,02036614 ! response to calcium ion GO:0051592 94 49 1,000 5,473E-04 0,02089202 ! epidermal cell differentiation GO:0009913 87 50 1,000 5,699E-04 0,02141849 ! positive regulation of growth GO:0045927 96 53 1,000 6,402E-04 0,02369791 ! response to UV GO:0009411 120 55 1,000 6,893E-04 0,02513519 ! nuclear export GO:0051168 110 59 1,000 7,929E-04 0,02848547 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 8,752E-04 0,03098587 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 9,322E-04 0,03253416 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 1,082E-03 0,03724619 ! negative regulation of kinase activity GO:0033673 145 70 1,000 1,114E-03 0,03779286 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 1,244E-03 0,04161779 ! negative regulation of transferase activity GO:0051348 155 74 1,000 1,244E-03 0,04105539 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 1,311E-03 0,04270581 ! regulation of actin filament-based process GO:0032970 170 79 1,000 1,416E-03 0,04550097 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 1,487E-03 0,04718707 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 1,561E-03 0,0488835 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 1,000 1,598E-03 0,04942063 ! mitochondrion organization GO:0007005 159 87 1,000 1,713E-03 0,05230523 ! response to inorganic substance GO:0010035 173 90 1,000 1,831E-03 0,05523372 ! positive regulation of protein modification process GO:0031401 156 90 1,000 1,831E-03 0,05456014 ! response to unfolded protein GO:0006986 139 90 1,000 1,831E-03 0,05390279 ! response to protein stimulus GO:0051789 158 96 1,000 2,08E-03 0,06048551 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 3,512E-03 0,10093964 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 3,512E-03 0,09976592 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 3,512E-03 0,09861918 ! positive regulation of helicase activity GO:0051096 12 5 0,000 3,512E-03 0,09749851 ! neuron fate determination GO:0048664 7 5 0,000 3,512E-03 0,09640302 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 3,512E-03 0,09533188 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 3,512E-03 0,09428428 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 3,512E-03 0,09325945 ! polyol transport GO:0015791 12 5 0,000 3,512E-03 0,09225666 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 3,512E-03 0,0912752 ! response to superoxide GO:0000303 10 5 0,000 3,512E-03 0,09031441 ! negative regulation of bone resorption GO:0045779 10 5 0,000 3,512E-03 0,08937364 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 3,512E-03 0,08845226 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 3,512E-03 0,08754968 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 3,512E-03 0,08666534 ! female meiosis GO:0007143 10 5 0,000 3,512E-03 0,08579869 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 3,512E-03 0,0849492 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 3,512E-03 0,08411636 ! hypothalamus development GO:0021854 9 5 0,000 3,512E-03 0,0832997 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 3,512E-03 0,08249874 ! cobalt ion transport GO:0006824 11 5 0,000 3,512E-03 0,08171304 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 3,512E-03 0,08094216 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 3,512E-03 0,08018569 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 3,512E-03 0,07944323 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 3,512E-03 0,07871439 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 3,512E-03 0,07799881 ! embryonic camera-type eye development GO:0031076 12 5 0,000 3,512E-03 0,07729612 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 3,512E-03 0,07660597 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 3,512E-03 0,07592804 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 3,512E-03 0,07526201 ! transposition GO:0032196 9 5 0,000 3,512E-03 0,07460756 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 3,512E-03 0,07396439 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 3,512E-03 0,07333221 ! negative chemotaxis GO:0050919 16 5 0,000 3,512E-03 0,07271075 ! positive regulation of histone modification GO:0031058 6 5 0,000 3,512E-03 0,07209974 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 3,512E-03 0,07149891 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 3,512E-03 0,07090801 ! behavioral response to pain GO:0048266 10 5 0,000 3,512E-03 0,0703268 ! clathrin coat assembly GO:0048268 15 5 0,000 3,512E-03 0,06975503 ! Notch receptor processing GO:0007220 11 5 0,000 3,512E-03 0,06919249 ! regulation of dopamine uptake GO:0051584 9 5 0,000 3,512E-03 0,06863895 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 3,512E-03 0,0680942 ! micturition GO:0060073 9 5 0,000 3,512E-03 0,06755802 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 3,512E-03 0,06703023 ! copulation GO:0007620 9 5 0,000 3,512E-03 0,06651061 ! glial cell fate commitment GO:0021781 14 5 0,000 3,512E-03 0,06599899 ! protein maturation by protein folding GO:0022417 14 5 0,000 3,512E-03 0,06549518 ! bioluminescence GO:0008218 9 5 0,000 3,512E-03 0,06499901 ! spermidine metabolic process GO:0008216 7 5 0,000 3,512E-03 0,06451029 ! regulation of potassium ion transport GO:0043266 10 5 0,000 3,512E-03 0,06402887 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 3,512E-03 0,06355459 ! apoptotic cell clearance GO:0043277 23 5 0,000 3,512E-03 0,06308727 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 3,512E-03 0,06262678 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 3,512E-03 0,06217296 ! lipoprotein particle clearance GO:0034381 10 5 0,000 3,512E-03 0,06172568 ! grooming behavior GO:0007625 6 5 0,000 3,512E-03 0,06128478 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 3,512E-03 0,06085013 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 3,512E-03 0,06042161 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 3,512E-03 0,05999908 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 3,512E-03 0,05958242 ! response to protozoan GO:0001562 13 5 0,000 3,512E-03 0,05917151 ! positive regulation of glycolysis GO:0045821 13 5 0,000 3,512E-03 0,05876623 ! lymph vessel development GO:0001945 10 5 0,000 3,512E-03 0,05836646 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 3,512E-03 0,05797209 ! endochondral ossification GO:0001958 17 5 0,000 3,512E-03 0,05758301 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 3,512E-03 0,05719913 ! single strand break repair GO:0000012 8 5 0,000 3,512E-03 0,05682032 ! parathyroid gland development GO:0060017 14 5 0,000 3,512E-03 0,05644651 ! anagen GO:0042640 7 5 0,000 3,512E-03 0,05607758 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 3,512E-03 0,05571344 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 3,512E-03 0,05535399 ! cytokine secretion GO:0050663 15 5 0,000 3,512E-03 0,05499916 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 3,512E-03 0,05464885 ! ceramide catabolic process GO:0046514 7 5 0,000 3,512E-03 0,05430297 ! skeletal myofibril assembly GO:0014866 12 5 0,000 3,512E-03 0,05396144 ! smooth muscle tissue development GO:0048745 32 5 0,000 3,512E-03 0,05362418 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 3,512E-03 0,05329111 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 3,512E-03 0,05296215 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 3,512E-03 0,05263723 ! cardiac muscle fiber development GO:0048739 12 5 0,000 3,512E-03 0,05231627 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 3,512E-03 0,05199921 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 3,512E-03 0,05168596 ! neutrophil mediated immunity GO:0002446 7 5 0,000 3,512E-03 0,05137646 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 3,512E-03 0,05107065 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 3,512E-03 0,05076846 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 3,512E-03 0,05046982 ! glycine biosynthetic process GO:0006545 7 5 0,000 3,512E-03 0,05017467 ! microvillus organization GO:0032528 8 5 0,000 3,512E-03 0,04988296 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 3,512E-03 0,04959462 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 3,512E-03 0,04930959 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 3,512E-03 0,04902782 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 3,512E-03 0,04874926 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 3,512E-03 0,04847384 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 3,512E-03 0,04820151 ! polyol catabolic process GO:0046174 9 5 0,000 3,512E-03 0,04793223 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 3,512E-03 0,04766594 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 3,512E-03 0,04740259 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 3,512E-03 0,04714214 ! muscle cell migration GO:0014812 8 5 0,000 3,512E-03 0,04688453 ! mitochondrial fission GO:0000266 8 5 0,000 3,512E-03 0,04662972 ! sister chromatid cohesion GO:0007062 15 5 0,000 3,512E-03 0,04637767 ! response to tumor necrosis factor GO:0034612 10 5 0,000 3,512E-03 0,04612833 ! mRNA transcription GO:0009299 10 5 0,000 3,512E-03 0,04588165 ! nerve growth factor processing GO:0032455 9 5 0,000 3,512E-03 0,0456376 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 3,512E-03 0,04539613 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 3,512E-03 0,04515721 ! anaerobic glycolysis GO:0019642 6 5 0,000 3,512E-03 0,04492078 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 3,512E-03 0,04468682 ! monocyte activation GO:0042117 10 5 0,000 3,512E-03 0,04445528 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 3,512E-03 0,04422613 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 3,512E-03 0,04399933 ! response to food GO:0032094 6 5 0,000 3,512E-03 0,04377484 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 3,512E-03 0,04355263 ! positive regulation of transporter activity GO:0032411 8 5 0,000 3,512E-03 0,04333267 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 3,512E-03 0,04311492 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 3,512E-03 0,04289935 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 3,512E-03 0,04268592 ! forebrain neuron development GO:0021884 13 5 0,000 3,512E-03 0,0424746 ! lipoprotein catabolic process GO:0042159 11 5 0,000 3,512E-03 0,04226536 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 3,512E-03 0,04205818 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 3,512E-03 0,04185302 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 3,512E-03 0,04164985 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 3,512E-03 0,04144864 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 3,512E-03 0,04124937 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 3,512E-03 0,041052 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 3,512E-03 0,04085652 ! lipid glycosylation GO:0030259 7 5 0,000 3,512E-03 0,04066289 ! nucleobase transport GO:0015851 6 5 0,000 3,512E-03 0,04047108 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 3,512E-03 0,04028108 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 3,512E-03 0,04009285 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 3,512E-03 0,03990637 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 3,512E-03 0,03972162 ! basic amino acid transport GO:0015802 12 5 0,000 3,512E-03 0,03953857 ! cellular glucose homeostasis GO:0001678 6 5 0,000 3,512E-03 0,0393572 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 3,512E-03 0,03917748 ! actin nucleation GO:0045010 11 5 0,000 3,512E-03 0,0389994 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 3,512E-03 0,03882294 ! depurination GO:0045007 5 5 0,000 3,512E-03 0,03864806 ! depyrimidination GO:0045008 10 5 0,000 3,512E-03 0,03847475 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 3,512E-03 0,03830299 ! regulation of centrosome cycle GO:0046605 7 5 0,000 3,512E-03 0,03813275 ! G2/M transition checkpoint GO:0031576 8 5 0,000 3,512E-03 0,03796402 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 3,512E-03 0,03779678 ! zinc ion homeostasis GO:0055069 9 5 0,000 3,512E-03 0,037631 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 3,512E-03 0,03746668 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 3,512E-03 0,03730378 ! forebrain morphogenesis GO:0048853 13 5 0,000 3,512E-03 0,03714229 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 3,512E-03 0,03698219 ! activated T cell proliferation GO:0050798 16 5 0,000 3,512E-03 0,03682347 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 3,512E-03 0,03666611 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 3,512E-03 0,03651008 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 3,512E-03 0,03635538 ! positive regulation of organ growth GO:0046622 6 5 0,000 3,512E-03 0,03620198 ! gamma-delta T cell activation GO:0046629 6 5 0,000 3,512E-03 0,03604987 ! response to arsenic GO:0046685 11 5 0,000 3,512E-03 0,03589903 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 3,512E-03 0,03574945 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 3,512E-03 0,03560112 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 3,512E-03 0,035454 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 3,512E-03 0,0353081 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 3,512E-03 0,0351634 ! response to mercury ion GO:0046689 8 5 0,000 3,512E-03 0,03501987 ! response to cadmium ion GO:0046686 7 5 0,000 3,512E-03 0,03487752 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 3,512E-03 0,03473631 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 3,512E-03 0,03459625 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 3,512E-03 0,03445731 ! bile acid biosynthetic process GO:0006699 7 5 0,000 3,512E-03 0,03431948 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 3,512E-03 0,03418275 ! ganglioside catabolic process GO:0006689 12 5 0,000 3,512E-03 0,0340471 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 3,512E-03 0,03391253 ! decidualization GO:0046697 11 5 0,000 3,512E-03 0,03377901 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 3,512E-03 0,03364655 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 3,512E-03 0,03351511 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 3,512E-03 0,0333847 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 3,512E-03 0,03325531 ! embryonic cleavage GO:0040016 6 5 0,000 3,512E-03 0,03312691 ! peroxisome fission GO:0016559 5 5 0,000 3,512E-03 0,0329995 ! histone demethylation GO:0016577 13 5 0,000 3,512E-03 0,03287306 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 3,512E-03 0,03274759 ! mitotic recombination GO:0006312 9 5 0,000 3,512E-03 0,03262308 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 3,512E-03 0,0324995 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 3,512E-03 0,03237686 ! metaphase plate congression GO:0051310 7 5 0,000 3,512E-03 0,03225515 ! regulation of sterol transport GO:0032371 7 5 0,000 3,512E-03 0,03213434 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 3,512E-03 0,03201444 ! enteric nervous system development GO:0048484 8 5 0,000 3,512E-03 0,03189542 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 3,512E-03 0,03177729 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 3,512E-03 0,03166003 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 3,512E-03 0,03154364 ! muscle cell proliferation GO:0033002 12 5 0,000 3,512E-03 0,03142809 ! skeletal muscle regeneration GO:0043403 8 5 0,000 3,512E-03 0,03131339 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 3,512E-03 0,03119952 ! B cell homeostasis GO:0001782 13 5 0,000 3,512E-03 0,03108648 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 3,512E-03 0,03097426 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 3,512E-03 0,03086284 ! metaphase GO:0051323 11 5 0,000 3,512E-03 0,03075222 ! melatonin biosynthetic process GO:0030187 7 5 0,000 3,512E-03 0,03064239 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 3,512E-03 0,03053334 ! cellular response to nutrient GO:0031670 8 5 0,000 3,512E-03 0,03042507 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 3,512E-03 0,03031756 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 3,512E-03 0,03021081 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 3,512E-03 0,0301048 ! regulation of hair follicle development GO:0051797 10 5 0,000 3,512E-03 0,02999954 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 3,512E-03 0,02989501 ! response to redox state GO:0051775 6 5 0,000 3,512E-03 0,02979121 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 3,512E-03 0,02968813 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 3,512E-03 0,02958576 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 3,512E-03 0,02948409 ! brown fat cell differentiation GO:0050873 7 5 0,000 3,512E-03 0,02938311 ! regulation of telomerase activity GO:0051972 7 5 0,000 3,512E-03 0,02928283 ! galactolipid metabolic process GO:0019374 7 5 0,000 3,512E-03 0,02918323 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 3,512E-03 0,0290843 ! porphyrin catabolic process GO:0006787 12 5 0,000 3,512E-03 0,02898604 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 3,512E-03 0,02888845 ! striatum development GO:0021756 14 5 0,000 3,512E-03 0,02879151 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 3,512E-03 0,02869521 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 3,512E-03 0,02859956 ! glial cell migration GO:0008347 10 5 0,000 3,512E-03 0,02850455 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 3,512E-03 0,02841016 ! neural plate morphogenesis GO:0001839 7 5 0,000 3,512E-03 0,0283164 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 3,512E-03 0,02822325 ! somatic stem cell maintenance GO:0035019 15 5 0,000 3,512E-03 0,02813072 ! T cell activation during immune response GO:0002286 9 5 0,000 3,512E-03 0,02803879 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 3,512E-03 0,02794746 ! negative regulation of lipase activity GO:0060192 8 5 0,000 3,512E-03 0,02785672 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 3,512E-03 0,02776657 ! neuroprotection GO:0043526 8 5 0,000 3,512E-03 0,027677 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 3,512E-03 0,027588 ! regulation of sensory perception GO:0051931 8 5 0,000 3,512E-03 0,02749958 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 3,512E-03 0,02741172 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 3,512E-03 0,02732442 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 3,512E-03 0,02723768 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 3,512E-03 0,02715148 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 3,512E-03 0,02706583 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 3,512E-03 0,02698072 ! sequestering of calcium ion GO:0051208 7 5 0,000 3,512E-03 0,02689614 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 3,512E-03 0,02681209 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 3,512E-03 0,02672856 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 3,512E-03 0,02664556 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 3,512E-03 0,02656306 ! spindle assembly GO:0051225 6 5 0,000 3,512E-03 0,02648108 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 3,512E-03 0,0263996 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 3,512E-03 0,02631862 ! protein palmitoylation GO:0018345 12 5 0,000 3,512E-03 0,02623813 ! drug metabolic process GO:0017144 7 5 0,000 3,512E-03 0,02615814 ! stem cell division GO:0017145 11 5 0,000 3,512E-03 0,02607863 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 3,512E-03 0,0259996 ! organ regeneration GO:0031100 7 5 0,000 3,512E-03 0,02592105 ! carnitine metabolic process GO:0009437 8 5 0,000 3,512E-03 0,02584298 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 3,512E-03 0,02576537 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 4,213E-03 0,03081547 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 4,213E-03 0,03072349 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 4,213E-03 0,03063205 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 4,213E-03 0,03054115 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 4,213E-03 0,03045079 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 4,213E-03 0,03036097 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 4,213E-03 0,03027167 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 4,213E-03 0,0301829 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 4,213E-03 0,03009464 ! response to oxygen radical GO:0000305 11 6 0,000 4,213E-03 0,0300069 ! positive regulation of axon extension GO:0045773 13 6 0,000 4,213E-03 0,02991967 ! myoblast cell fate commitment GO:0048625 18 6 0,000 4,213E-03 0,02983295 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 4,213E-03 0,02974673 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 4,213E-03 0,029661 ! regulation of interferon-beta production GO:0032648 8 6 0,000 4,213E-03 0,02957577 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 4,213E-03 0,02949103 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 4,213E-03 0,02940677 ! forebrain regionalization GO:0021871 9 6 0,000 4,213E-03 0,02932299 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 4,213E-03 0,02923968 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 4,213E-03 0,02915685 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 4,213E-03 0,02907449 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 4,213E-03 0,02899259 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 4,213E-03 0,02891115 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 4,213E-03 0,02883016 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 4,213E-03 0,02874963 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 4,213E-03 0,02866955 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 4,213E-03 0,02858991 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 4,213E-03 0,02851071 ! malate metabolic process GO:0006108 13 6 0,000 4,213E-03 0,02843196 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 4,213E-03 0,02835363 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 4,213E-03 0,02827574 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 4,213E-03 0,02819827 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 4,213E-03 0,02812122 ! protein refolding GO:0042026 15 6 0,000 4,213E-03 0,0280446 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 4,213E-03 0,02796839 ! opsonization GO:0008228 8 6 0,000 4,213E-03 0,0278926 ! mating behavior GO:0007617 7 6 0,000 4,213E-03 0,02781721 ! erythrocyte maturation GO:0043249 8 6 0,000 4,213E-03 0,02774223 ! embryonic hemopoiesis GO:0035162 16 6 0,000 4,213E-03 0,02766766 ! protein amino acid dealkylation GO:0008214 15 6 0,000 4,213E-03 0,02759348 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 4,213E-03 0,0275197 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 4,213E-03 0,02744631 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 4,213E-03 0,02737332 ! response to interferon-gamma GO:0034341 16 6 0,000 4,213E-03 0,02730071 ! toxin metabolic process GO:0009404 11 6 0,000 4,213E-03 0,02722849 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 4,213E-03 0,02715664 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 4,213E-03 0,02708518 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 4,213E-03 0,02701409 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 4,213E-03 0,02694337 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 4,213E-03 0,02687302 ! cGMP-mediated signaling GO:0019934 14 6 0,000 4,213E-03 0,02680304 ! dorsal spinal cord development GO:0021516 10 6 0,000 4,213E-03 0,02673342 ! activation of MAPKKK activity GO:0000185 12 6 0,000 4,213E-03 0,02666417 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 4,213E-03 0,02659527 ! thymic T cell selection GO:0045061 16 6 0,000 4,213E-03 0,02652672 ! sphingoid catabolic process GO:0046521 8 6 0,000 4,213E-03 0,02645853 ! protein lipoylation GO:0009249 10 6 0,000 4,213E-03 0,02639069 ! transepithelial chloride transport GO:0030321 12 6 0,000 4,213E-03 0,02632319 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 4,213E-03 0,02625604 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 4,213E-03 0,02618923 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 4,213E-03 0,02612276 ! glutamate catabolic process GO:0006538 12 6 0,000 4,213E-03 0,02605663 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 4,213E-03 0,02599083 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 4,213E-03 0,02592536 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 4,213E-03 0,02586022 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 4,213E-03 0,02579541 ! hyperosmotic response GO:0006972 10 6 0,000 4,213E-03 0,02573092 ! L-serine biosynthetic process GO:0006564 7 6 0,000 4,213E-03 0,02566675 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 4,213E-03 0,02560291 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 4,213E-03 0,02553937 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 4,213E-03 0,02547616 ! urea metabolic process GO:0019627 7 6 0,000 4,213E-03 0,02541325 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 4,213E-03 0,02535066 ! neutrophil activation GO:0042119 7 6 0,000 4,213E-03 0,02528837 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 4,213E-03 0,02522639 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 4,213E-03 0,02516471 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 4,213E-03 0,02510334 ! paraxial mesoderm development GO:0048339 16 6 0,000 4,213E-03 0,02504226 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 4,213E-03 0,02498148 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 4,213E-03 0,02492099 ! neuron apoptosis GO:0051402 15 6 0,000 4,213E-03 0,02486079 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 4,213E-03 0,02480089 ! T cell mediated immunity GO:0002456 17 6 0,000 4,213E-03 0,02474127 ! negative regulation of platelet activation GO:0010544 9 6 0,000 4,213E-03 0,02468194 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 4,213E-03 0,02462289 ! carnitine transport GO:0015879 10 6 0,000 4,213E-03 0,02456412 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 4,213E-03 0,02450564 ! positive regulation of exocytosis GO:0045921 11 6 0,000 4,213E-03 0,02444743 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 4,213E-03 0,0243895 ! early endosome to late endosome transport GO:0045022 16 6 0,000 4,213E-03 0,02433184 ! 5S class rRNA transcription GO:0042791 13 6 0,000 4,213E-03 0,02427445 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 4,213E-03 0,02421734 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 4,213E-03 0,02416049 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 4,213E-03 0,02410391 ! sodium ion homeostasis GO:0055078 12 6 0,000 4,213E-03 0,02404759 ! establishment of spindle localization GO:0051293 16 6 0,000 4,213E-03 0,02399153 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 4,213E-03 0,02393574 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 4,213E-03 0,0238802 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 4,213E-03 0,02382493 ! response to UV-C GO:0010225 14 6 0,000 4,213E-03 0,0237699 ! astrocyte development GO:0014002 16 6 0,000 4,213E-03 0,02371513 ! protein targeting to lysosome GO:0006622 12 6 0,000 4,213E-03 0,02366062 ! purine base biosynthetic process GO:0009113 17 6 0,000 4,213E-03 0,02360635 ! interaction with symbiont GO:0051702 14 6 0,000 4,213E-03 0,02355233 ! regulation of dendrite development GO:0050773 16 6 0,000 4,213E-03 0,02349856 ! peptidyl-arginine modification GO:0018195 13 6 0,000 4,213E-03 0,02344503 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 4,213E-03 0,02339175 ! response to copper ion GO:0046688 10 6 0,000 4,213E-03 0,0233387 ! response to exogenous dsRNA GO:0043330 13 6 0,000 4,213E-03 0,0232859 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 4,213E-03 0,02323334 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 4,213E-03 0,02318101 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 4,213E-03 0,02312892 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 4,213E-03 0,02307706 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 4,213E-03 0,02302543 ! regulation of dopamine secretion GO:0014059 14 6 0,000 4,213E-03 0,02297404 ! nucleoside catabolic process GO:0009164 10 6 0,000 4,213E-03 0,02292287 ! hair follicle maturation GO:0048820 8 6 0,000 4,213E-03 0,02287193 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 4,213E-03 0,02282122 ! Schwann cell development GO:0014044 15 6 0,000 4,213E-03 0,02277073 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 4,213E-03 0,02272046 ! response to pheromone GO:0019236 6 6 0,000 4,213E-03 0,02267041 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 4,213E-03 0,02262059 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 4,213E-03 0,02257098 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 4,213E-03 0,02252159 ! base conversion or substitution editing GO:0016553 6 6 0,000 4,213E-03 0,02247242 ! subpallium development GO:0021544 15 6 0,000 4,213E-03 0,02242346 ! neural tube patterning GO:0021532 8 6 0,000 4,213E-03 0,02237471 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 4,213E-03 0,02232618 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 4,213E-03 0,02227785 ! maintenance of organ identity GO:0048496 9 6 0,000 4,213E-03 0,02222974 ! G2 phase GO:0051319 16 6 0,000 4,213E-03 0,02218183 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 4,213E-03 0,02213412 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 4,213E-03 0,02208663 ! oxygen homeostasis GO:0032364 10 6 0,000 4,213E-03 0,02203933 ! establishment of planar polarity GO:0001736 7 6 0,000 4,213E-03 0,02199224 ! regulation of mast cell activation GO:0033003 13 6 0,000 4,213E-03 0,02194535 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 4,213E-03 0,02189866 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 4,213E-03 0,02185216 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 4,213E-03 0,02180586 ! receptor internalization GO:0031623 11 6 0,000 4,213E-03 0,02175976 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 4,213E-03 0,02171386 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 4,213E-03 0,02166814 ! neutrophil homeostasis GO:0001780 11 6 0,000 4,213E-03 0,02162262 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 4,213E-03 0,02157729 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 4,213E-03 0,02153215 ! protein deubiquitination GO:0016579 16 6 0,000 4,213E-03 0,0214872 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 4,213E-03 0,02144243 ! protein destabilization GO:0031648 9 6 0,000 4,213E-03 0,02139785 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 4,213E-03 0,02135346 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 4,213E-03 0,02130925 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 4,213E-03 0,02126522 ! regulation of viral transcription GO:0046782 11 6 0,000 4,213E-03 0,02122138 ! progesterone metabolic process GO:0042448 12 6 0,000 4,213E-03 0,02117771 ! negative regulation of axon extension GO:0030517 24 6 0,000 4,213E-03 0,02113423 ! removal of superoxide radicals GO:0019430 12 6 0,000 4,213E-03 0,02109092 ! triglyceride catabolic process GO:0019433 10 6 0,000 4,213E-03 0,02104779 ! determination of adult lifespan GO:0008340 17 6 0,000 4,213E-03 0,02100483 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 4,213E-03 0,02096205 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 4,213E-03 0,02091945 ! neural plate development GO:0001840 9 6 0,000 4,213E-03 0,02087701 ! catecholamine transport GO:0051937 9 6 0,000 4,213E-03 0,02083475 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 4,213E-03 0,02079266 ! sensory cilium assembly GO:0035058 10 6 0,000 4,213E-03 0,02075074 ! organ or tissue specific immune response GO:0002251 8 6 0,000 4,213E-03 0,02070899 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 4,213E-03 0,02066741 ! maternal placenta development GO:0001893 12 6 0,000 4,213E-03 0,02062599 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 4,213E-03 0,02058474 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 4,213E-03 0,02054365 ! negative regulation of B cell activation GO:0050869 14 6 0,000 4,213E-03 0,02050273 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 4,213E-03 0,02046196 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 4,213E-03 0,02042137 ! positive regulation of coagulation GO:0050820 13 6 0,000 4,213E-03 0,02038093 ! cellular anion homeostasis GO:0030002 11 6 0,000 4,213E-03 0,02034065 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 4,914E-03 0,02367596 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 4,914E-03 0,02362935 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 4,914E-03 0,02358293 ! behavioral response to cocaine GO:0048148 14 7 0,000 4,914E-03 0,02353669 ! regulation of helicase activity GO:0051095 16 7 0,000 4,914E-03 0,02349063 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 4,914E-03 0,02344475 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 4,914E-03 0,02339905 ! sleep GO:0030431 16 7 0,000 4,914E-03 0,02335352 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 4,914E-03 0,02330818 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 4,914E-03 0,02326301 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 4,914E-03 0,02321801 ! prostate gland development GO:0030850 14 7 0,000 4,914E-03 0,02317319 ! nucleotide-sugar transport GO:0015780 11 7 0,000 4,914E-03 0,02312854 ! synaptonemal complex assembly GO:0007130 10 7 0,000 4,914E-03 0,02308406 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 4,914E-03 0,02303975 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 4,914E-03 0,02299561 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 4,914E-03 0,02295165 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 4,914E-03 0,02290784 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 4,914E-03 0,02286421 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 4,914E-03 0,02282074 ! SMAD protein complex assembly GO:0007183 13 7 0,000 4,914E-03 0,02277744 ! glycolipid transport GO:0046836 11 7 0,000 4,914E-03 0,0227343 ! protein amino acid sulfation GO:0006477 10 7 0,000 4,914E-03 0,02269132 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 4,914E-03 0,02264851 ! neuron adhesion GO:0007158 14 7 0,000 4,914E-03 0,02260586 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 4,914E-03 0,02256337 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 4,914E-03 0,02252103 ! establishment of tissue polarity GO:0007164 8 7 0,000 4,914E-03 0,02247886 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 4,914E-03 0,02243684 ! mRNA stabilization GO:0048255 18 7 0,000 4,914E-03 0,02239498 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 4,914E-03 0,02235328 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 4,914E-03 0,02231173 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 4,914E-03 0,02227034 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 4,914E-03 0,02222909 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 4,914E-03 0,022188 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 4,914E-03 0,02214707 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 4,914E-03 0,02210628 ! lipoprotein transport GO:0042953 14 7 0,000 4,914E-03 0,02206564 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 4,914E-03 0,02202516 ! rhythmic behavior GO:0007622 17 7 0,000 4,914E-03 0,02198482 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 4,914E-03 0,02194463 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 4,914E-03 0,02190458 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 4,914E-03 0,02186468 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 4,914E-03 0,02182493 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 4,914E-03 0,02178532 ! regulation of odontogenesis GO:0042481 14 7 0,000 4,914E-03 0,02174585 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 4,914E-03 0,02170653 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 4,914E-03 0,02166735 ! mechanosensory behavior GO:0007638 16 7 0,000 4,914E-03 0,02162831 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 4,914E-03 0,02158941 ! positive regulation of isotype switching GO:0045830 17 7 0,000 4,914E-03 0,02155065 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 4,914E-03 0,02151203 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 4,914E-03 0,02147354 ! protein-cofactor linkage GO:0018065 13 7 0,000 4,914E-03 0,0214352 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 4,914E-03 0,02139699 ! spinal cord patterning GO:0021511 14 7 0,000 4,914E-03 0,02135892 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 4,914E-03 0,02132098 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 4,914E-03 0,02128317 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 4,914E-03 0,02124551 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 4,914E-03 0,02120797 ! adrenal gland development GO:0030325 17 7 0,000 4,914E-03 0,02117057 ! cysteine metabolic process GO:0006534 13 7 0,000 4,914E-03 0,02113329 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 4,914E-03 0,02109615 ! ovulation GO:0030728 10 7 0,000 4,914E-03 0,02105914 ! adenohypophysis development GO:0021984 11 7 0,000 4,914E-03 0,02102226 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 4,914E-03 0,02098551 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 4,914E-03 0,02094888 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 4,914E-03 0,02091239 ! microtubule nucleation GO:0007020 21 7 0,000 4,914E-03 0,02087602 ! proline biosynthetic process GO:0006561 10 7 0,000 4,914E-03 0,02083978 ! tryptophan metabolic process GO:0006568 11 7 0,000 4,914E-03 0,02080366 ! thyroid hormone generation GO:0006590 13 7 0,000 4,914E-03 0,02076767 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 4,914E-03 0,0207318 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 4,914E-03 0,02069605 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 4,914E-03 0,02066043 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 4,914E-03 0,02062493 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 4,914E-03 0,02058956 ! galactose metabolic process GO:0006012 13 7 0,000 4,914E-03 0,0205543 ! vesicle fusion GO:0006906 20 7 0,000 4,914E-03 0,02051916 ! response to dietary excess GO:0002021 8 7 0,000 4,914E-03 0,02048415 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 4,914E-03 0,02044925 ! intracellular pH reduction GO:0051452 13 7 0,000 4,914E-03 0,02041447 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 4,914E-03 0,02037981 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 4,914E-03 0,02034527 ! organ growth GO:0035265 15 7 0,000 4,914E-03 0,02031085 ! nucleoside transport GO:0015858 11 7 0,000 4,914E-03 0,02027654 ! nucleoside salvage GO:0043174 11 7 0,000 4,914E-03 0,02024235 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 4,914E-03 0,02020827 ! male sex determination GO:0030238 15 7 0,000 4,914E-03 0,0201743 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 4,914E-03 0,02014045 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 4,914E-03 0,02010672 ! parturition GO:0007567 16 7 0,000 4,914E-03 0,02007309 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 4,914E-03 0,02003958 ! rRNA modification GO:0000154 14 7 0,000 4,914E-03 0,02000618 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 4,914E-03 0,0199729 ! spindle checkpoint GO:0031577 16 7 0,000 4,914E-03 0,01993972 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 4,914E-03 0,01990665 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 4,914E-03 0,01987369 ! monocyte differentiation GO:0030224 16 7 0,000 4,914E-03 0,01984084 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 4,914E-03 0,0198081 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 4,914E-03 0,01977547 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 4,914E-03 0,01974295 ! hyaluronan metabolic process GO:0030212 9 7 0,000 4,914E-03 0,01971053 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 4,914E-03 0,01967821 ! anterograde axon cargo transport GO:0008089 18 7 0,000 4,914E-03 0,01964601 ! fibrinolysis GO:0042730 11 7 0,000 4,914E-03 0,01961391 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 4,914E-03 0,01958191 ! skeletal muscle contraction GO:0003009 8 7 0,000 4,914E-03 0,01955002 ! eating behavior GO:0042755 8 7 0,000 4,914E-03 0,01951823 ! B cell lineage commitment GO:0002326 21 7 0,000 4,914E-03 0,01948654 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 4,914E-03 0,01945496 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 4,914E-03 0,01942348 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 4,914E-03 0,0193921 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 4,914E-03 0,01936082 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 4,914E-03 0,01932965 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 4,914E-03 0,01929857 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 4,914E-03 0,01926759 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 4,914E-03 0,01923672 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 4,914E-03 0,01920594 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 4,914E-03 0,01917526 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 4,914E-03 0,01914467 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 4,914E-03 0,01911419 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 4,914E-03 0,0190838 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 4,914E-03 0,01905351 ! histone ubiquitination GO:0016574 9 7 0,000 4,914E-03 0,01902331 ! regulation of meiosis GO:0040020 12 7 0,000 4,914E-03 0,01899321 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 4,914E-03 0,01896321 ! T cell lineage commitment GO:0002360 16 7 0,000 4,914E-03 0,0189333 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 4,914E-03 0,01890348 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 4,914E-03 0,01887376 ! membrane to membrane docking GO:0022614 14 7 0,000 4,914E-03 0,01884413 ! transcription termination GO:0006353 14 7 0,000 4,914E-03 0,01881459 ! coenzyme A metabolic process GO:0015936 12 7 0,000 4,914E-03 0,01878515 ! anaphase GO:0051322 18 7 0,000 4,914E-03 0,0187558 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 4,914E-03 0,01872654 ! axonal fasciculation GO:0007413 19 7 0,000 4,914E-03 0,01869737 ! negative regulation of nuclear division GO:0051784 15 7 0,000 4,914E-03 0,01866829 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 4,914E-03 0,0186393 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 4,914E-03 0,0186104 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 4,914E-03 0,0185816 ! diuresis GO:0030146 12 7 0,000 4,914E-03 0,01855288 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 4,914E-03 0,01852424 ! thiamin metabolic process GO:0006772 7 7 0,000 4,914E-03 0,0184957 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 4,914E-03 0,01846725 ! antibiotic transport GO:0042891 9 7 0,000 4,914E-03 0,01843888 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 4,914E-03 0,0184106 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 4,914E-03 0,01838241 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 4,914E-03 0,0183543 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 4,914E-03 0,01832628 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 4,914E-03 0,01829834 ! melanin biosynthetic process GO:0042438 10 7 0,000 4,914E-03 0,01827049 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 4,914E-03 0,01824272 ! dopamine biosynthetic process GO:0042416 18 7 0,000 4,914E-03 0,01821504 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 4,914E-03 0,01818744 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 4,914E-03 0,01815993 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 4,914E-03 0,01813249 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 4,914E-03 0,01810514 ! endosome to lysosome transport GO:0008333 12 7 0,000 4,914E-03 0,01807788 ! protein modification by small protein removal GO:0070646 19 7 0,000 4,914E-03 0,01805069 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 4,914E-03 0,01802359 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 4,914E-03 0,01799657 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 4,914E-03 0,01796963 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 4,914E-03 0,01794277 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 4,914E-03 0,01791599 ! muscle adaptation GO:0043500 13 7 0,000 4,914E-03 0,01788929 ! embryonic heart tube development GO:0035050 14 7 0,000 4,914E-03 0,01786266 ! retina homeostasis GO:0001895 12 7 0,000 4,914E-03 0,01783612 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 4,914E-03 0,01780966 ! protein amino acid prenylation GO:0018346 19 7 0,000 4,914E-03 0,01778327 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 4,914E-03 0,01775697 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 4,914E-03 0,01773074 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 5,614E-03 0,02022699 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 5,614E-03 0,0201972 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 5,614E-03 0,0201675 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 5,614E-03 0,02013788 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 5,614E-03 0,02010835 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 5,614E-03 0,02007891 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 5,614E-03 0,02004956 ! male meiosis GO:0007140 9 8 0,000 5,614E-03 0,02002029 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 5,614E-03 0,0199911 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 5,614E-03 0,019962 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 5,614E-03 0,01993299 ! meiotic prophase I GO:0007128 14 8 0,000 5,614E-03 0,01990406 ! response to zinc ion GO:0010043 12 8 0,000 5,614E-03 0,01987521 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 5,614E-03 0,01984645 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 5,614E-03 0,01981777 ! oligopeptide transport GO:0006857 16 8 0,000 5,614E-03 0,01978917 ! actin-myosin filament sliding GO:0033275 13 8 0,000 5,614E-03 0,01976066 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 5,614E-03 0,01973223 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 5,614E-03 0,01970388 ! signal peptide processing GO:0006465 12 8 0,000 5,614E-03 0,01967561 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 5,614E-03 0,01964742 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 5,614E-03 0,01961931 ! macrophage chemotaxis GO:0048246 12 8 0,000 5,614E-03 0,01959128 ! succinate metabolic process GO:0006105 17 8 0,000 5,614E-03 0,01956333 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 5,614E-03 0,01953547 ! membrane hyperpolarization GO:0060081 11 8 0,000 5,614E-03 0,01950768 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 5,614E-03 0,01947997 ! estrogen metabolic process GO:0008210 17 8 0,000 5,614E-03 0,01945234 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 5,614E-03 0,01942478 ! T-helper 1 type immune response GO:0042088 12 8 0,000 5,614E-03 0,01939731 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 5,614E-03 0,01936991 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 5,614E-03 0,01934259 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 5,614E-03 0,01931535 ! reflex GO:0060004 17 8 0,000 5,614E-03 0,01928818 ! endothelial cell differentiation GO:0045446 17 8 0,000 5,614E-03 0,01926109 ! glycerolipid catabolic process GO:0046503 14 8 0,000 5,614E-03 0,01923408 ! hemoglobin metabolic process GO:0020027 14 8 0,000 5,614E-03 0,01920714 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 5,614E-03 0,01918028 ! pigment granule organization GO:0048753 17 8 0,000 5,614E-03 0,01915349 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 5,614E-03 0,01912677 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 5,614E-03 0,01910014 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 5,614E-03 0,01907357 ! astrocyte differentiation GO:0048708 19 8 0,000 5,614E-03 0,01904708 ! histidine catabolic process GO:0006548 10 8 0,000 5,614E-03 0,01902066 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 5,614E-03 0,01899432 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 5,614E-03 0,01896805 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 5,614E-03 0,01894185 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 5,614E-03 0,01891572 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 5,614E-03 0,01888967 ! regulation of pigmentation during development GO:0048070 25 8 0,000 5,614E-03 0,01886368 ! melanin metabolic process GO:0006582 17 8 0,000 5,614E-03 0,01883777 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 5,614E-03 0,01881193 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 5,614E-03 0,01878616 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 5,614E-03 0,01876046 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 5,614E-03 0,01873483 ! macrophage activation GO:0042116 13 8 0,000 5,614E-03 0,01870927 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 5,614E-03 0,01868378 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 5,614E-03 0,01865836 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 5,614E-03 0,01863301 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 5,614E-03 0,01860773 ! purine salvage GO:0043101 12 8 0,000 5,614E-03 0,01858252 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 5,614E-03 0,01855737 ! regulation of vascular permeability GO:0043114 12 8 0,000 5,614E-03 0,01853229 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 5,614E-03 0,01850728 ! osteoblast development GO:0002076 17 8 0,000 5,614E-03 0,01848234 ! positive regulation of vasodilation GO:0045909 14 8 0,000 5,614E-03 0,01845747 ! negative regulation of translational initiation GO:0045947 12 8 0,000 5,614E-03 0,01843266 ! Schwann cell differentiation GO:0014037 21 8 0,000 5,614E-03 0,01840792 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 5,614E-03 0,01838324 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 5,614E-03 0,01835863 ! response to UV-B GO:0010224 17 8 0,000 5,614E-03 0,01833409 ! protein targeting to vacuole GO:0006623 14 8 0,000 5,614E-03 0,01830961 ! protein retention in ER lumen GO:0006621 14 8 0,000 5,614E-03 0,0182852 ! intermediate filament organization GO:0045109 12 8 0,000 5,614E-03 0,01826085 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 5,614E-03 0,01823657 ! cellular extravasation GO:0045123 13 8 0,000 5,614E-03 0,01821235 ! cardiac muscle cell development GO:0055013 14 8 0,000 5,614E-03 0,01818819 ! response to antibiotic GO:0046677 11 8 0,000 5,614E-03 0,0181641 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 5,614E-03 0,01814008 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 5,614E-03 0,01811611 ! DNA topological change GO:0006265 12 8 0,000 5,614E-03 0,01809221 ! response to tropane GO:0014073 15 8 0,000 5,614E-03 0,01806838 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 5,614E-03 0,0180446 ! melanosome transport GO:0032402 13 8 0,000 5,614E-03 0,01802089 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 5,614E-03 0,01799724 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 5,614E-03 0,01797365 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 5,614E-03 0,01795013 ! mast cell activation GO:0045576 14 8 0,000 5,614E-03 0,01792666 ! multicellular organismal aging GO:0010259 20 8 0,000 5,614E-03 0,01790326 ! gas homeostasis GO:0033483 14 8 0,000 5,614E-03 0,01787992 ! dendrite morphogenesis GO:0048813 14 8 0,000 5,614E-03 0,01785664 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 5,614E-03 0,01783342 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 5,614E-03 0,01781026 ! nucleosome disassembly GO:0006337 14 8 0,000 5,614E-03 0,01778716 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 5,614E-03 0,01776412 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 5,614E-03 0,01774114 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 5,614E-03 0,01771821 ! establishment of chromosome localization GO:0051303 14 8 0,000 5,614E-03 0,01769535 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 5,614E-03 0,01767255 ! intracellular lipid transport GO:0032365 16 8 0,000 5,614E-03 0,0176498 ! response to tumor cell GO:0002347 16 8 0,000 5,614E-03 0,01762712 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 5,614E-03 0,01760449 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 5,614E-03 0,01758192 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 5,614E-03 0,01755941 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 5,614E-03 0,01753695 ! positive regulation of epidermis development GO:0045684 13 8 0,000 5,614E-03 0,01751456 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 5,614E-03 0,01749222 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 5,614E-03 0,01746993 ! hormone catabolic process GO:0042447 17 8 0,000 5,614E-03 0,01744771 ! glycolipid catabolic process GO:0019377 16 8 0,000 5,614E-03 0,01742554 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 5,614E-03 0,01740342 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 5,614E-03 0,01738137 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 5,614E-03 0,01735936 ! positive regulation of glucose import GO:0046326 8 8 0,000 5,614E-03 0,01733742 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 5,614E-03 0,01731553 ! adult feeding behavior GO:0008343 10 8 0,000 5,614E-03 0,01729369 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 5,614E-03 0,01727191 ! ATP catabolic process GO:0006200 11 8 0,000 5,614E-03 0,01725019 ! blastocyst growth GO:0001832 19 8 0,000 5,614E-03 0,01722851 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 5,614E-03 0,0172069 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 5,614E-03 0,01718534 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 5,614E-03 0,01716383 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 5,614E-03 0,01714237 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 5,614E-03 0,01712097 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 5,614E-03 0,01709962 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 5,614E-03 0,01707833 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 5,614E-03 0,01705709 ! amino sugar catabolic process GO:0046348 11 8 0,000 5,614E-03 0,0170359 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 5,614E-03 0,01701476 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 5,614E-03 0,01699368 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 5,614E-03 0,01697265 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 5,614E-03 0,01695167 ! behavioral response to nicotine GO:0035095 12 8 0,000 5,614E-03 0,01693074 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 5,614E-03 0,01690986 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 5,614E-03 0,01688904 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 5,614E-03 0,01686826 ! NAD biosynthetic process GO:0009435 17 8 0,000 5,614E-03 0,01684754 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 5,614E-03 0,01682687 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 5,614E-03 0,01680625 ! axon extension GO:0048675 16 9 0,000 6,313E-03 0,01887751 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 6,313E-03 0,01885444 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 6,313E-03 0,01883142 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 6,313E-03 0,01880845 ! pentose-phosphate shunt GO:0006098 16 9 0,000 6,313E-03 0,01878554 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 6,313E-03 0,01876269 ! cell proliferation in forebrain GO:0021846 18 9 0,000 6,313E-03 0,01873989 ! neutral lipid catabolic process GO:0046461 14 9 0,000 6,313E-03 0,01871715 ! reproductive behavior GO:0019098 22 9 0,000 6,313E-03 0,01869446 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 6,313E-03 0,01867183 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 6,313E-03 0,01864925 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 6,313E-03 0,01862673 ! UTP metabolic process GO:0046051 10 9 0,000 6,313E-03 0,01860426 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 6,313E-03 0,01858184 ! induction of positive chemotaxis GO:0050930 17 9 0,000 6,313E-03 0,01855948 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 6,313E-03 0,01853717 ! artery development GO:0060840 25 9 0,000 6,313E-03 0,01851492 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 6,313E-03 0,01849272 ! regulation of glycolysis GO:0006110 20 9 0,000 6,313E-03 0,01847057 ! cerebral cortex cell migration GO:0021795 18 9 0,000 6,313E-03 0,01844848 ! equilibrioception GO:0050957 20 9 0,000 6,313E-03 0,01842644 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 6,313E-03 0,01840445 ! chemosensory behavior GO:0007635 21 9 0,000 6,313E-03 0,01838251 ! microtubule bundle formation GO:0001578 22 9 0,000 6,313E-03 0,01836063 ! middle ear morphogenesis GO:0042474 14 9 0,000 6,313E-03 0,0183388 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 6,313E-03 0,01831702 ! leukocyte degranulation GO:0043299 16 9 0,000 6,313E-03 0,01829529 ! ganglioside metabolic process GO:0001573 22 9 0,000 6,313E-03 0,01827361 ! negative regulation of endocytosis GO:0045806 12 9 0,000 6,313E-03 0,01825199 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 6,313E-03 0,01823041 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 6,313E-03 0,01820889 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 6,313E-03 0,01818742 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 6,313E-03 0,01816599 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 6,313E-03 0,01814462 ! protein targeting to ER GO:0045047 25 9 0,000 6,313E-03 0,0181233 ! ceramide biosynthetic process GO:0046513 20 9 0,000 6,313E-03 0,01810203 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 6,313E-03 0,01808081 ! T cell selection GO:0045058 27 9 0,000 6,313E-03 0,01805964 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 6,313E-03 0,01803851 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 6,313E-03 0,01801744 ! glycine catabolic process GO:0006546 15 9 0,000 6,313E-03 0,01799642 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 6,313E-03 0,01797544 ! endosome organization GO:0007032 20 9 0,000 6,313E-03 0,01795452 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 6,313E-03 0,01793364 ! regulation of type I interferon production GO:0032479 12 9 0,000 6,313E-03 0,01791281 ! mannose metabolic process GO:0006013 13 9 0,000 6,313E-03 0,01789203 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 6,313E-03 0,0178713 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 6,313E-03 0,01785061 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 6,313E-03 0,01782998 ! Rac protein signal transduction GO:0016601 20 9 0,000 6,313E-03 0,01780939 ! receptor clustering GO:0043113 20 9 0,000 6,313E-03 0,01778885 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 6,313E-03 0,01776835 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 6,313E-03 0,0177479 ! retinol metabolic process GO:0042572 20 9 0,000 6,313E-03 0,0177275 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 6,313E-03 0,01770715 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 6,313E-03 0,01768685 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 6,313E-03 0,01766659 ! macrophage differentiation GO:0030225 15 9 0,000 6,313E-03 0,01764637 ! oligodendrocyte development GO:0014003 11 9 0,000 6,313E-03 0,0176262 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 6,313E-03 0,01760608 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 6,313E-03 0,01758601 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 6,313E-03 0,01756598 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 6,313E-03 0,01754599 ! response to amine stimulus GO:0014075 13 9 0,000 6,313E-03 0,01752606 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 6,313E-03 0,01750616 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 6,313E-03 0,01748631 ! erythrocyte development GO:0048821 17 9 0,000 6,313E-03 0,01746651 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 6,313E-03 0,01744675 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 6,313E-03 0,01742704 ! renal water homeostasis GO:0003091 15 9 0,000 6,313E-03 0,01740737 ! postreplication repair GO:0006301 25 9 0,000 6,313E-03 0,01738774 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 6,313E-03 0,01736816 ! icosanoid secretion GO:0032309 15 9 0,000 6,313E-03 0,01734863 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 6,313E-03 0,01732913 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 6,313E-03 0,01730968 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 6,313E-03 0,01729028 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 6,313E-03 0,01727092 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 6,313E-03 0,0172516 ! sterol catabolic process GO:0016127 14 9 0,000 6,313E-03 0,01723232 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 6,313E-03 0,01721309 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 6,313E-03 0,0171939 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 6,313E-03 0,01717475 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 6,313E-03 0,01715565 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 6,313E-03 0,01713659 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 6,313E-03 0,01711757 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 6,313E-03 0,01709859 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 6,313E-03 0,01707966 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 6,313E-03 0,01706076 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 6,313E-03 0,01704191 ! regulation of synaptogenesis GO:0051963 15 9 0,000 6,313E-03 0,0170231 ! purine base metabolic process GO:0006144 25 9 0,000 6,313E-03 0,01700433 ! pigment granule transport GO:0051904 17 9 0,000 6,313E-03 0,0169856 ! regulation of telomere maintenance GO:0032204 17 9 0,000 6,313E-03 0,01696692 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 6,313E-03 0,01694827 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 6,313E-03 0,01692967 ! regulation of muscle adaptation GO:0043502 14 9 0,000 6,313E-03 0,01691111 ! regulation of amino acid transport GO:0051955 12 9 0,000 6,313E-03 0,01689258 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 6,313E-03 0,0168741 ! mitochondrion localization GO:0051646 18 9 0,000 6,313E-03 0,01685566 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 7,012E-03 0,01870175 ! regulation of developmental growth GO:0048638 16 10 0,000 7,012E-03 0,01868136 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 7,012E-03 0,01866101 ! autophagic vacuole formation GO:0000045 17 10 0,000 7,012E-03 0,0186407 ! negative regulation of blood pressure GO:0045776 26 10 0,000 7,012E-03 0,01862044 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 7,012E-03 0,01860022 ! associative learning GO:0008306 21 10 0,000 7,012E-03 0,01858005 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 7,012E-03 0,01855992 ! phosphate transport GO:0006817 24 10 0,000 7,012E-03 0,01853983 ! cell volume homeostasis GO:0006884 17 10 0,000 7,012E-03 0,01851979 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 7,012E-03 0,01849979 ! CTP metabolic process GO:0046036 11 10 0,000 7,012E-03 0,01847983 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 7,012E-03 0,01845992 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 7,012E-03 0,01844005 ! GTP metabolic process GO:0046039 11 10 0,000 7,012E-03 0,01842022 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 7,012E-03 0,01840044 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 7,012E-03 0,01838069 ! social behavior GO:0035176 29 10 0,000 7,012E-03 0,01836099 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 7,012E-03 0,01834133 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 7,012E-03 0,01832172 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 7,012E-03 0,01830214 ! androgen metabolic process GO:0008209 17 10 0,000 7,012E-03 0,01828261 ! phospholipid efflux GO:0033700 19 10 0,000 7,012E-03 0,01826312 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 7,012E-03 0,01824367 ! bile acid and bile salt transport GO:0015721 15 10 0,000 7,012E-03 0,01822426 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 7,012E-03 0,0182049 ! positive regulation of heart contraction GO:0045823 17 10 0,000 7,012E-03 0,01818557 ! lung alveolus development GO:0048286 26 10 0,000 7,012E-03 0,01816628 ! pathogenesis GO:0009405 17 10 0,000 7,012E-03 0,01814704 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 7,012E-03 0,01812784 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 7,012E-03 0,01810868 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 7,012E-03 0,01808955 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 7,012E-03 0,01807047 ! endoderm development GO:0007492 18 10 0,000 7,012E-03 0,01805143 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 7,012E-03 0,01803243 ! arginine catabolic process GO:0006527 17 10 0,000 7,012E-03 0,01801347 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 7,012E-03 0,01799454 ! proline metabolic process GO:0006560 13 10 0,000 7,012E-03 0,01797566 ! glucan biosynthetic process GO:0009250 14 10 0,000 7,012E-03 0,01795682 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 7,012E-03 0,01793802 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 7,012E-03 0,01791925 ! V(D)J recombination GO:0033151 34 10 0,000 7,012E-03 0,01790053 ! reverse cholesterol transport GO:0043691 19 10 0,000 7,012E-03 0,01788184 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 7,012E-03 0,0178632 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 19 10 0,000 7,012E-03 0,01784459 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 7,012E-03 0,01782602 ! regulation of sodium ion transport GO:0002028 26 10 0,000 7,012E-03 0,01780749 ! multicellular organism growth GO:0035264 19 10 0,000 7,012E-03 0,017789 ! phagocytosis, engulfment GO:0006911 33 10 0,000 7,012E-03 0,01777055 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 7,012E-03 0,01775213 ! ruffle organization GO:0031529 17 10 0,000 7,012E-03 0,01773375 ! epithelial cell development GO:0002064 21 10 0,000 7,012E-03 0,01771542 ! lens development in camera-type eye GO:0002088 17 10 0,000 7,012E-03 0,01769711 ! retinoic acid metabolic process GO:0042573 14 10 0,000 7,012E-03 0,01767885 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 7,012E-03 0,01766063 ! positive regulation of translational initiation GO:0045948 12 10 0,000 7,012E-03 0,01764244 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 7,012E-03 0,01762429 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 7,012E-03 0,01760617 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 7,012E-03 0,0175881 ! motor axon guidance GO:0008045 22 10 0,000 7,012E-03 0,01757006 ! copper ion homeostasis GO:0055070 13 10 0,000 7,012E-03 0,01755206 ! regulation of bone resorption GO:0045124 25 10 0,000 7,012E-03 0,01753409 ! protein heterooligomerization GO:0051291 17 10 0,000 7,012E-03 0,01751616 ! regulation of gliogenesis GO:0014013 23 10 0,000 7,012E-03 0,01749827 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 7,012E-03 0,01748041 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 7,012E-03 0,0174626 ! segment specification GO:0007379 15 10 0,000 7,012E-03 0,01744481 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 7,012E-03 0,01742707 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 7,012E-03 0,01740936 ! blastoderm segmentation GO:0007350 19 10 0,000 7,012E-03 0,01739168 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 7,012E-03 0,01737404 ! response to dsRNA GO:0043331 23 10 0,000 7,012E-03 0,01735644 ! DNA ligation GO:0006266 18 10 0,000 7,012E-03 0,01733887 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 7,012E-03 0,01732134 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 7,012E-03 0,01730385 ! melanosome localization GO:0032400 16 10 0,000 7,012E-03 0,01728638 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 7,012E-03 0,01726896 ! regulation of B cell differentiation GO:0045577 24 10 0,000 7,012E-03 0,01725157 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 7,012E-03 0,01723421 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 7,012E-03 0,01721689 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 7,012E-03 0,01719961 ! induction of an organ GO:0001759 17 10 0,000 7,012E-03 0,01718235 ! leukocyte activation during immune response GO:0002366 15 10 0,000 7,012E-03 0,01716514 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 7,012E-03 0,01714795 ! protein sumoylation GO:0016925 17 10 0,000 7,012E-03 0,01713081 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 7,012E-03 0,01711369 ! hindbrain morphogenesis GO:0021575 19 10 0,000 7,012E-03 0,01709661 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 7,012E-03 0,01707957 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 7,012E-03 0,01706256 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 7,012E-03 0,01704558 ! salivary gland development GO:0007431 28 10 0,000 7,012E-03 0,01702863 ! ubiquinone metabolic process GO:0006743 17 10 0,000 7,012E-03 0,01701172 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 7,012E-03 0,01699485 ! midbrain development GO:0030901 14 10 0,000 7,012E-03 0,016978 ! musculoskeletal movement GO:0050881 16 10 0,000 7,012E-03 0,01696119 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 7,012E-03 0,01694442 ! methionine biosynthetic process GO:0009086 21 10 0,000 7,012E-03 0,01692767 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 7,012E-03 0,01691096 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 7,012E-03 0,01689429 ! quaternary ammonium group transport GO:0015697 22 10 0,000 7,012E-03 0,01687764 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 7,012E-03 0,01686103 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 7,012E-03 0,01684445 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 7,012E-03 0,0168279 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 7,012E-03 0,01681139 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 7,012E-03 0,01679491 ! establishment of pigment granule localization GO:0051905 18 10 0,000 7,012E-03 0,01677846 ! blastocyst formation GO:0001825 18 10 0,000 7,012E-03 0,01676204 ! regulation of fibrinolysis GO:0051917 20 10 0,000 7,012E-03 0,01674566 ! cerebellar cortex development GO:0021695 16 10 0,000 7,012E-03 0,0167293 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 7,012E-03 0,01671298 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 7,012E-03 0,01669669 ! response to nicotine GO:0035094 20 10 0,000 7,012E-03 0,01668043 ! negative regulation of immune effector process GO:0002698 23 10 0,000 7,012E-03 0,01666421 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 7,012E-03 0,01664801 ! negative regulation of muscle development GO:0048635 27 11 0,000 7,711E-03 0,01828886 ! respiratory burst GO:0045730 17 11 0,000 7,711E-03 0,01827113 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 7,711E-03 0,01825342 ! neuron fate specification GO:0048665 18 11 0,000 7,711E-03 0,01823575 ! telencephalon cell migration GO:0022029 23 11 0,000 7,711E-03 0,01821811 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 7,711E-03 0,01820051 ! thyroid gland development GO:0030878 26 11 0,000 7,711E-03 0,01818294 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 7,711E-03 0,01816541 ! synapsis GO:0007129 14 11 0,000 7,711E-03 0,01814791 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 7,711E-03 0,01813044 ! Golgi vesicle budding GO:0048194 26 11 0,000 7,711E-03 0,01811301 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 7,711E-03 0,01809561 ! response to pain GO:0048265 27 11 0,000 7,711E-03 0,01807824 ! detection of mechanical stimulus GO:0050982 22 11 0,000 7,711E-03 0,01806091 ! blood vessel remodeling GO:0001974 30 11 0,000 7,711E-03 0,01804361 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 7,711E-03 0,01802635 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 7,711E-03 0,01800911 ! bone resorption GO:0045453 16 11 0,000 7,711E-03 0,01799191 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 7,711E-03 0,01797474 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 7,711E-03 0,01795761 ! negative regulation of proteolysis GO:0045861 25 11 0,000 7,711E-03 0,01794051 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 7,711E-03 0,01792344 ! melanocyte differentiation GO:0030318 20 11 0,000 7,711E-03 0,0179064 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 7,711E-03 0,01788939 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 7,711E-03 0,01787242 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 7,711E-03 0,01785548 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 7,711E-03 0,01783857 ! regulation of intracellular pH GO:0051453 21 11 0,000 7,711E-03 0,01782169 ! substrate-bound cell migration GO:0006929 14 11 0,000 7,711E-03 0,01780485 ! UV protection GO:0009650 20 11 0,000 7,711E-03 0,01778804 ! adult heart development GO:0007512 16 11 0,000 7,711E-03 0,01777126 ! chondrocyte differentiation GO:0002062 27 11 0,000 7,711E-03 0,01775451 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 7,711E-03 0,01773779 ! macroautophagy GO:0016236 19 11 0,000 7,711E-03 0,0177211 ! temperature homeostasis GO:0001659 18 11 0,000 7,711E-03 0,01770445 ! behavioral fear response GO:0001662 27 11 0,000 7,711E-03 0,01768782 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 7,711E-03 0,01767123 ! negative regulation of ossification GO:0030279 27 11 0,000 7,711E-03 0,01765467 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 7,711E-03 0,01763814 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 7,711E-03 0,01762164 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 7,711E-03 0,01760517 ! alpha-beta T cell activation GO:0046631 26 11 0,000 7,711E-03 0,01758873 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 7,711E-03 0,01757232 ! regulation of organ growth GO:0046620 14 11 0,000 7,711E-03 0,01755595 ! pigment granule localization GO:0051875 20 11 0,000 7,711E-03 0,0175396 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 7,711E-03 0,01752328 ! vasoconstriction GO:0042310 20 11 0,000 7,711E-03 0,017507 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 7,711E-03 0,01749074 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 7,711E-03 0,01747452 ! embryonic axis specification GO:0000578 19 11 0,000 7,711E-03 0,01745832 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 7,711E-03 0,01744216 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 7,711E-03 0,01742602 ! nitric oxide metabolic process GO:0046209 17 11 0,000 7,711E-03 0,01740992 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 7,711E-03 0,01739384 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 7,711E-03 0,0173778 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 7,711E-03 0,01736178 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 7,711E-03 0,01734579 ! prophase GO:0051324 17 11 0,000 7,711E-03 0,01732983 ! neuroblast proliferation GO:0007405 25 11 0,000 7,711E-03 0,01731391 ! nucleosome positioning GO:0016584 15 11 0,000 7,711E-03 0,01729801 ! regulation of isotype switching GO:0045191 24 11 0,000 7,711E-03 0,01728214 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 7,711E-03 0,0172663 ! negative regulation of neurological system process GO:0031645 21 11 0,000 7,711E-03 0,01725049 ! apical protein localization GO:0045176 18 11 0,000 7,711E-03 0,0172347 ! acid secretion GO:0046717 20 11 0,000 7,711E-03 0,01721895 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 7,711E-03 0,01720322 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 7,711E-03 0,01718753 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 7,711E-03 0,01717186 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 7,711E-03 0,01715622 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 7,711E-03 0,01714061 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 7,711E-03 0,01712503 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 7,711E-03 0,01710947 ! cholesterol efflux GO:0033344 21 11 0,000 7,711E-03 0,01709395 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 7,711E-03 0,01707845 ! oocyte development GO:0048599 20 11 0,000 7,711E-03 0,01706298 ! negative regulation of glucose import GO:0046325 18 11 0,000 7,711E-03 0,01704754 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 7,711E-03 0,01703213 ! embryonic gut development GO:0048566 19 11 0,000 7,711E-03 0,01701674 ! regulation of organic acid transport GO:0032890 19 11 0,000 7,711E-03 0,01700138 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 7,711E-03 0,01698605 ! activation of innate immune response GO:0002218 16 11 0,000 7,711E-03 0,01697075 GO:0002758|innate immune response-activating signal transduction, ! cardiac cell differentiation GO:0035051 36 11 0,000 7,711E-03 0,01695547 ! lysogeny GO:0030069 22 11 0,000 7,711E-03 0,01694023 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 7,711E-03 0,01692501 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 7,711E-03 0,01690981 ! sequestering of metal ion GO:0051238 15 11 0,000 7,711E-03 0,01689465 ! nucleus localization GO:0051647 22 11 0,000 7,711E-03 0,01687951 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 8,409E-03 0,01839132 ! positive regulation of blood pressure GO:0045777 18 12 0,000 8,409E-03 0,01837487 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 8,409E-03 0,01835845 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 8,409E-03 0,01834206 ! virus-host interaction GO:0019048 30 12 0,000 8,409E-03 0,01832569 ! regulation of B cell proliferation GO:0030888 22 12 0,000 8,409E-03 0,01830936 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 8,409E-03 0,01829306 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 8,409E-03 0,01827678 ! protein complex disassembly GO:0043241 28 12 0,000 8,409E-03 0,01826053 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 8,409E-03 0,01824432 ! regulation of cell projection assembly GO:0060491 33 12 0,000 8,409E-03 0,01822813 ! hippocampus development GO:0021766 29 12 0,000 8,409E-03 0,01821197 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 8,409E-03 0,01819584 ! cytokine biosynthetic process GO:0042089 23 12 0,000 8,409E-03 0,01817974 ! T cell proliferation GO:0042098 32 12 0,000 8,409E-03 0,01816366 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 8,409E-03 0,01814762 ! regulation of exit from mitosis GO:0007096 19 12 0,000 8,409E-03 0,0181316 ! ventral spinal cord development GO:0021517 25 12 0,000 8,409E-03 0,01811561 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 8,409E-03 0,01809965 ! drug transport GO:0015893 16 12 0,000 8,409E-03 0,01808372 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 8,409E-03 0,01806781 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 8,409E-03 0,01805193 ! tyrosine metabolic process GO:0006570 19 12 0,000 8,409E-03 0,01803609 ! polyamine metabolic process GO:0006595 18 12 0,000 8,409E-03 0,01802026 ! focal adhesion formation GO:0048041 37 12 0,000 8,409E-03 0,01800447 ! mitotic spindle organization GO:0007052 23 12 0,000 8,409E-03 0,01798871 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 8,409E-03 0,01797297 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 8,409E-03 0,01795726 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 8,409E-03 0,01794157 ! lipid digestion GO:0044241 21 12 0,000 8,409E-03 0,01792592 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 8,409E-03 0,01791029 ! entry into host cell GO:0030260 34 12 0,000 8,409E-03 0,01789469 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 8,409E-03 0,01787911 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 8,409E-03 0,01786357 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 8,409E-03 0,01784805 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 8,409E-03 0,01783255 ! protein targeting to peroxisome GO:0006625 27 12 0,000 8,409E-03 0,01781709 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 8,409E-03 0,01780165 ! regulation of phagocytosis GO:0050764 17 12 0,000 8,409E-03 0,01778624 ! snRNA metabolic process GO:0016073 30 12 0,000 8,409E-03 0,01777085 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 8,409E-03 0,01775549 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 8,409E-03 0,01774016 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 8,409E-03 0,01772485 ! cranial nerve development GO:0021545 23 12 0,000 8,409E-03 0,01770957 ! fucose catabolic process GO:0019317 25 12 0,000 8,409E-03 0,01769432 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 8,409E-03 0,01767909 ! histone acetylation GO:0016573 27 12 0,000 8,409E-03 0,01766389 ! mRNA polyadenylation GO:0006378 24 12 0,000 8,409E-03 0,01764871 ! autonomic nervous system development GO:0048483 24 12 0,000 8,409E-03 0,01763356 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 8,409E-03 0,01761844 ! zymogen activation GO:0031638 18 12 0,000 8,409E-03 0,01760334 ! peptidyl-lysine modification GO:0018205 21 12 0,000 8,409E-03 0,01758827 ! T cell homeostasis GO:0043029 28 12 0,000 8,409E-03 0,01757323 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 8,409E-03 0,01755821 ! glutathione biosynthetic process GO:0006750 15 12 0,000 8,409E-03 0,01754321 ! regulation of leukocyte migration GO:0002685 29 12 0,000 8,409E-03 0,01752824 ! oocyte differentiation GO:0009994 21 12 0,000 8,409E-03 0,0175133 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 8,409E-03 0,01749838 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 8,409E-03 0,01748349 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 8,409E-03 0,01746862 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 8,409E-03 0,01745378 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 8,409E-03 0,01743897 ! defense response to fungus GO:0050832 15 12 0,000 8,409E-03 0,01742417 ! developmental induction GO:0031128 22 12 0,000 8,409E-03 0,01740941 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 8,409E-03 0,01739467 ! lamellipodium assembly GO:0030032 24 12 0,000 8,409E-03 0,01737995 ! response to cold GO:0009409 17 12 0,000 8,409E-03 0,01736526 ! establishment of cell polarity GO:0030010 21 12 0,000 8,409E-03 0,01735059 ! regulation of synapse organization GO:0050807 18 12 0,000 8,409E-03 0,01733595 ! localization within membrane GO:0051668 26 12 0,000 8,409E-03 0,01732133 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 9,107E-03 0,01874265 ! cGMP metabolic process GO:0046068 18 13 0,000 9,107E-03 0,01872687 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 9,107E-03 0,01871112 ! regulation of chemokine production GO:0032642 18 13 0,000 9,107E-03 0,0186954 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 9,107E-03 0,0186797 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 9,107E-03 0,01866403 ! peroxisomal transport GO:0043574 28 13 0,000 9,107E-03 0,01864838 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 9,107E-03 0,01863276 ! cartilage condensation GO:0001502 22 13 0,000 9,107E-03 0,01861717 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 9,107E-03 0,01860161 ! organelle fusion GO:0048284 36 13 0,000 9,107E-03 0,01858607 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 9,107E-03 0,01857055 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 9,107E-03 0,01855506 ! pseudouridine synthesis GO:0001522 19 13 0,000 9,107E-03 0,0185396 ! endocrine pancreas development GO:0031018 25 13 0,000 9,107E-03 0,01852416 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 9,107E-03 0,01850875 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 9,107E-03 0,01849337 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 9,107E-03 0,01847801 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 9,107E-03 0,01846267 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 9,107E-03 0,01844736 ! methionine metabolic process GO:0006555 31 13 0,000 9,107E-03 0,01843208 ! plasma membrane organization GO:0007009 27 13 0,000 9,107E-03 0,01841682 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 9,107E-03 0,01840159 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 9,107E-03 0,01838638 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 9,107E-03 0,0183712 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 9,107E-03 0,01835604 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 9,107E-03 0,01834091 ! cytokine metabolic process GO:0042107 24 13 0,000 9,107E-03 0,0183258 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 9,107E-03 0,01831072 ! exocrine system development GO:0035272 34 13 0,000 9,107E-03 0,01829566 ! asymmetric protein localization GO:0008105 24 13 0,000 9,107E-03 0,01828063 ! membrane protein proteolysis GO:0033619 33 13 0,000 9,107E-03 0,01826562 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 9,107E-03 0,01825063 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 9,107E-03 0,01823567 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 9,107E-03 0,01822074 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 9,107E-03 0,01820583 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 9,107E-03 0,01819094 ! protein homotetramerization GO:0051289 24 13 0,000 9,107E-03 0,01817608 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 9,107E-03 0,01816124 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 9,107E-03 0,01814643 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 9,107E-03 0,01813164 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 9,107E-03 0,01811687 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 9,107E-03 0,01810213 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 9,107E-03 0,01808742 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 9,107E-03 0,01807272 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 9,107E-03 0,01805805 ! histone methylation GO:0016571 29 13 0,000 9,107E-03 0,01804341 ! chromatin silencing GO:0006342 29 13 0,000 9,107E-03 0,01802879 ! gland morphogenesis GO:0022612 31 13 0,000 9,107E-03 0,01801419 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 9,107E-03 0,01799961 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 9,107E-03 0,01798506 ! regulation of epidermis development GO:0045682 19 13 0,000 9,107E-03 0,01797053 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 9,107E-03 0,01795603 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 9,107E-03 0,01794155 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 9,107E-03 0,01792709 ! spleen development GO:0048536 24 13 0,000 9,107E-03 0,01791266 ! regulation of mRNA stability GO:0043488 32 13 0,000 9,107E-03 0,01789825 ! digestive tract morphogenesis GO:0048546 31 13 0,000 9,107E-03 0,01788386 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 9,107E-03 0,01786949 ! anterior/posterior axis specification GO:0009948 22 13 0,000 9,107E-03 0,01785515 ! regulation of RNA splicing GO:0043484 22 13 0,000 9,107E-03 0,01784083 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 9,107E-03 0,01782654 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 9,107E-03 0,01781227 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 9,107E-03 0,01779802 ! mRNA 3'-end processing GO:0031124 25 13 0,000 9,107E-03 0,01778379 ! insulin secretion GO:0030073 24 13 0,000 9,107E-03 0,01776959 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 9,107E-03 0,0177554 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 9,107E-03 0,01774124 ! acrosome reaction GO:0007340 19 13 0,000 9,107E-03 0,01772711 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 9,107E-03 0,01771299 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 9,107E-03 0,0176989 ! rRNA transcription GO:0009303 28 14 0,000 9,804E-03 0,01903878 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 9,804E-03 0,01902366 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 9,804E-03 0,01900856 ! water transport GO:0006833 21 14 0,000 9,804E-03 0,01899349 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 9,804E-03 0,01897844 ! non-recombinational repair GO:0000726 29 14 0,000 9,804E-03 0,01896341 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 9,804E-03 0,01894841 ! retina development in camera-type eye GO:0060041 28 14 0,000 9,804E-03 0,01893343 ! hair follicle morphogenesis GO:0031069 27 14 0,000 9,804E-03 0,01891847 ! RNA polyadenylation GO:0043631 32 14 0,000 9,804E-03 0,01890354 ! lipid localization GO:0010876 32 14 0,000 9,804E-03 0,01888863 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 9,804E-03 0,01887375 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 9,804E-03 0,01885889 ! regulated secretory pathway GO:0045055 24 14 0,000 9,804E-03 0,01884405 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 9,804E-03 0,01882924 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 9,804E-03 0,01881445 ! arginine metabolic process GO:0006525 21 14 0,000 9,804E-03 0,01879968 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 9,804E-03 0,01878493 ! cell-cell junction assembly GO:0007043 32 14 0,000 9,804E-03 0,01877021 ! regulation of heart rate GO:0002027 25 14 0,000 9,804E-03 0,01875551 ! fear response GO:0042596 34 14 0,000 9,804E-03 0,01874084 ! organic alcohol transport GO:0015850 29 14 0,000 9,804E-03 0,01872618 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 9,804E-03 0,01871155 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 9,804E-03 0,01869695 ! neutral amino acid transport GO:0015804 28 14 0,000 9,804E-03 0,01868236 ! bone mineralization GO:0030282 18 14 0,000 9,804E-03 0,0186678 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 9,804E-03 0,01865326 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 9,804E-03 0,01863875 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 9,804E-03 0,01862425 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 9,804E-03 0,01860978 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 9,804E-03 0,01859533 ! regulation of cellular pH GO:0030641 27 14 0,000 9,804E-03 0,01858091 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 9,804E-03 0,0185665 ! ribosome assembly GO:0042255 18 14 0,000 9,804E-03 0,01855212 ! cerebellum development GO:0021549 23 14 0,000 9,804E-03 0,01853776 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 9,804E-03 0,01852343 ! negative regulation of protein secretion GO:0050709 30 14 0,000 9,804E-03 0,01850911 ! response to gamma radiation GO:0010332 30 14 0,000 9,804E-03 0,01849482 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 9,804E-03 0,01848055 ! NADP metabolic process GO:0006739 24 14 0,000 9,804E-03 0,0184663 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 9,804E-03 0,01845207 ! oxygen transport GO:0015671 22 14 0,000 9,804E-03 0,01843787 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 9,804E-03 0,01842368 ! male genitalia development GO:0030539 26 14 0,000 9,804E-03 0,01840952 ! regulation of RNA stability GO:0043487 33 14 0,000 9,804E-03 0,01839538 ! regulation of axon extension GO:0030516 43 14 0,000 9,804E-03 0,01838127 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 9,804E-03 0,01836717 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 9,804E-03 0,01835309 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01050058 0,01964235 ! lactation GO:0007595 30 15 0,000 0,01050058 0,01962732 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,01050058 0,01961231 ! reproductive cellular process GO:0048610 22 15 0,000 0,01050058 0,01959733 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01050058 0,01958237 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,01050058 0,01956743 ! superoxide anion generation GO:0042554 22 15 0,000 0,01050058 0,01955252 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,01050058 0,01953763 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,01050058 0,01952276 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,01050058 0,01950791 ! copper ion transport GO:0006825 22 15 0,000 0,01050058 0,01949309 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,01050058 0,01947829 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,01050058 0,01946351 ! sulfate transport GO:0008272 27 15 0,000 0,01050058 0,01944875 ! response to cAMP GO:0051591 25 15 0,000 0,01050058 0,01943402 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,01050058 0,01941931 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,01050058 0,01940462 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,01050058 0,01938995 ! response to hexose stimulus GO:0009746 25 15 0,000 0,01050058 0,01937531 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,01050058 0,01936068 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,01050058 0,01934608 ! vesicle coating GO:0006901 38 15 0,000 0,01050058 0,0193315 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,01050058 0,01931695 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,01050058 0,01930241 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,01050058 0,0192879 ! regulation of exocytosis GO:0017157 26 15 0,000 0,01050058 0,01927341 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,01050058 0,01925894 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,01050058 0,01924449 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,01050058 0,01923006 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,01050058 0,01921566 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,01050058 0,01920128 ! regulation of vasodilation GO:0042312 27 15 0,000 0,01050058 0,01918692 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,01050058 0,01917258 ! histone deacetylation GO:0016575 24 15 0,000 0,01050058 0,01915826 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01050058 0,01914396 ! water homeostasis GO:0030104 28 15 0,000 0,01050058 0,01912968 ! cofactor transport GO:0051181 30 15 0,000 0,01050058 0,01911543 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01050058 0,0191012 ! muscle maintenance GO:0046716 26 15 0,000 0,01050058 0,01908698 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,01050058 0,01907279 ! intestinal absorption GO:0050892 31 15 0,000 0,01050058 0,01905862 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01050058 0,01904447 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,01050058 0,01903035 ! heme biosynthetic process GO:0006783 33 15 0,000 0,01050058 0,01901624 ! cell killing GO:0001906 32 15 0,000 0,01050058 0,01900215 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,01050058 0,01898809 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,01050058 0,01897404 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,01050058 0,01896002 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,01050058 0,01894602 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,01050058 0,01893203 ! actin filament polymerization GO:0030041 27 15 0,000 0,01050058 0,01891807 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,01050058 0,01890413 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01119684 0,02014276 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,01119684 0,02012794 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,01119684 0,02011314 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,01119684 0,02009836 ! bone remodeling GO:0046849 28 16 0,000 0,01119684 0,02008361 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,01119684 0,02006887 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,01119684 0,02005416 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01119684 0,02003947 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,01119684 0,0200248 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,01119684 0,02001015 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,01119684 0,01999552 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,01119684 0,01998092 ! startle response GO:0001964 28 16 0,000 0,01119684 0,01996633 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,01119684 0,01995177 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,01119684 0,01993723 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,01119684 0,0199227 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,01119684 0,01990821 ! protein polyubiquitination GO:0000209 41 16 0,000 0,01119684 0,01989373 ! glutamate metabolic process GO:0006536 25 16 0,000 0,01119684 0,01987927 ! pituitary gland development GO:0021983 30 16 0,000 0,01119684 0,01986483 ! response to osmotic stress GO:0006970 27 16 0,000 0,01119684 0,01985042 ! lysosomal transport GO:0007041 31 16 0,000 0,01119684 0,01983602 ! fructose metabolic process GO:0006000 25 16 0,000 0,01119684 0,01982165 ! L-amino acid transport GO:0015807 33 16 0,000 0,01119684 0,01980729 ! stem cell development GO:0048864 46 16 0,000 0,01119684 0,01979296 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01119684 0,01977865 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 36 16 0,000 0,01119684 0,01976436 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,01119684 0,01975009 ! negative regulation of immune response GO:0050777 38 16 0,000 0,01119684 0,01973584 ! axon cargo transport GO:0008088 46 16 0,000 0,01119684 0,01972161 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,01119684 0,0197074 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,01119684 0,01969321 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,01119684 0,01967905 ! DNA replication initiation GO:0006270 28 16 0,000 0,01119684 0,0196649 ! neuron recognition GO:0008038 40 16 0,000 0,01119684 0,01965077 ! mRNA splice site selection GO:0006376 44 16 0,000 0,01119684 0,01963666 ! tissue regeneration GO:0042246 27 16 0,000 0,01119684 0,01962258 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,01119684 0,01960851 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,01119684 0,01959447 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,01119684 0,01958044 ! biomineral formation GO:0031214 22 16 0,000 0,01119684 0,01956643 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,01119684 0,01955245 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,01119684 0,01953848 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,01119684 0,01952454 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01119684 0,01951061 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,01119684 0,0194967 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,01119684 0,01948282 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,01119684 0,01946895 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,01119684 0,0194551 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01119684 0,01944127 ! peptide hormone processing GO:0016486 27 16 0,000 0,01119684 0,01942747 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,01189263 0,02062008 ! metencephalon development GO:0022037 32 17 0,000 0,01189263 0,02060546 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,01189263 0,02059085 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,01189263 0,02057627 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,01189263 0,02056171 ! signal complex assembly GO:0007172 47 17 0,000 0,01189263 0,02054717 ! filopodium assembly GO:0046847 42 17 0,000 0,01189263 0,02053264 ! endothelial cell migration GO:0043542 31 17 0,000 0,01189263 0,02051814 ! gene silencing by RNA GO:0031047 38 17 0,000 0,01189263 0,02050366 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,01189263 0,0204892 ! glial cell development GO:0021782 28 17 0,000 0,01189263 0,02047477 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,01189263 0,02046035 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,01189263 0,02044595 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,01189263 0,02043157 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,01189263 0,02041721 ! myoblast differentiation GO:0045445 50 17 0,000 0,01189263 0,02040287 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,01189263 0,02038856 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,01189263 0,02037426 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,01189263 0,02035998 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,01189263 0,02034572 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,01189263 0,02033149 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,01189263 0,02031727 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,01189263 0,02030307 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,01189263 0,02028889 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,01189263 0,02027473 ! membrane budding GO:0006900 42 17 0,000 0,01189263 0,02026059 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,01189263 0,02024648 ! regulation of protein binding GO:0043393 33 17 0,000 0,01189263 0,02023238 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,01189263 0,0202183 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,01189263 0,02020424 ! genitalia development GO:0048806 32 17 0,000 0,01189263 0,0201902 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,01189263 0,02017618 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,01189263 0,02016217 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,01189263 0,02014819 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,01189263 0,02013423 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,01189263 0,02012029 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,01189263 0,02010636 ! steroid catabolic process GO:0006706 34 17 0,000 0,01189263 0,02009246 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,01189263 0,02007857 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,01189263 0,0200647 ! gas transport GO:0015669 26 17 0,000 0,01189263 0,02005086 ! organic cation transport GO:0015695 32 17 0,000 0,01189263 0,02003703 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,01189263 0,02002322 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,01189263 0,02000943 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,01189263 0,01999566 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,01258795 0,02115018 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,01258795 0,02113564 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,01258795 0,02112113 ! limbic system development GO:0021761 40 18 0,000 0,01258795 0,02110663 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01258795 0,02109216 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,01258795 0,0210777 ! adult walking behavior GO:0007628 36 18 0,000 0,01258795 0,02106326 ! patterning of blood vessels GO:0001569 43 18 0,000 0,01258795 0,02104885 ! heart looping GO:0001947 34 18 0,000 0,01258795 0,02103445 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,01258795 0,02102007 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,01258795 0,02100571 ! centrosome cycle GO:0007098 26 18 0,000 0,01258795 0,02099137 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,01258795 0,02097706 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,01258795 0,02096276 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,01258795 0,02094848 ! glycine metabolic process GO:0006544 30 18 0,000 0,01258795 0,02093422 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01258795 0,02091997 ! response to retinoic acid GO:0032526 31 18 0,000 0,01258795 0,02090575 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,01258795 0,02089155 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,01258795 0,02087737 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,01258795 0,0208632 ! DNA integration GO:0015074 32 18 0,000 0,01258795 0,02084906 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,01258795 0,02083493 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,01258795 0,02082083 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,01258795 0,02080674 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,01258795 0,02079267 ! neural crest cell migration GO:0001755 41 18 0,000 0,01258795 0,02077862 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,01258795 0,02076459 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,01258795 0,02075058 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,01258795 0,02073659 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,01258795 0,02072262 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,01258795 0,02070866 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,01258795 0,02069473 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,01258795 0,02068081 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,01258795 0,02066691 ! detection of bacterium GO:0016045 22 18 0,000 0,01258795 0,02065303 ! nerve development GO:0021675 34 18 0,000 0,01258795 0,02063917 ! defense response to virus GO:0051607 43 18 0,000 0,01258795 0,02062533 ! microspike assembly GO:0030035 46 18 0,000 0,01258795 0,0206115 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,01258795 0,0205977 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,01258795 0,02058391 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,0132828 0,02170561 ! positive regulation of translation GO:0045727 31 19 0,000 0,0132828 0,0216911 ! negative regulation of defense response GO:0031348 27 19 0,000 0,0132828 0,02167661 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,0132828 0,02166214 ! neuron maturation GO:0042551 46 19 0,000 0,0132828 0,02164769 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,0132828 0,02163326 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,0132828 0,02161884 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,0132828 0,02160445 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,0132828 0,02159008 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,0132828 0,02157572 ! inositol metabolic process GO:0006020 33 19 0,000 0,0132828 0,02156139 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0132828 0,02154707 ! memory GO:0007613 34 19 0,000 0,0132828 0,02153277 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,0132828 0,02151849 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,0132828 0,02150423 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,0132828 0,02148999 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,0132828 0,02147577 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,0132828 0,02146156 ! cerebral cortex development GO:0021987 40 19 0,000 0,0132828 0,02144738 ! pigmentation during development GO:0048066 42 19 0,000 0,0132828 0,02143321 ! response to vitamin A GO:0033189 32 19 0,000 0,0132828 0,02141907 ! heme metabolic process GO:0042168 40 19 0,000 0,0132828 0,02140494 ! neuromuscular junction development GO:0007528 43 19 0,000 0,0132828 0,02139083 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,0132828 0,02137674 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,0132828 0,02136266 ! response to fungus GO:0009620 26 19 0,000 0,0132828 0,02134861 ! peptide cross-linking GO:0018149 39 19 0,000 0,0132828 0,02133457 ! protein export from nucleus GO:0006611 40 19 0,000 0,0132828 0,02132056 ! heart process GO:0003015 32 19 0,000 0,0132828 0,02130656 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,0132828 0,02129258 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,0132828 0,02127861 ! visual learning GO:0008542 38 19 0,000 0,0132828 0,02126467 ! cellular pigmentation GO:0033059 37 19 0,000 0,0132828 0,02125074 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,0132828 0,02123684 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,0132828 0,02122295 ! vitamin transport GO:0051180 31 19 0,000 0,0132828 0,02120908 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,0132828 0,02119522 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,0132828 0,02118139 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,0132828 0,02116757 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,0132828 0,02115377 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,0132828 0,02113999 ! cilium assembly GO:0042384 38 19 0,000 0,0132828 0,02112623 ! peptide hormone secretion GO:0030072 32 19 0,000 0,0132828 0,02111248 ! protein secretion GO:0009306 45 20 0,000 0,01397718 0,02220173 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,01397718 0,0221873 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,01397718 0,0221729 ! positive regulation of ossification GO:0045778 50 20 0,000 0,01397718 0,02215851 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,01397718 0,02214414 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,01397718 0,02212979 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,01397718 0,02211545 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,01397718 0,02210114 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,01397718 0,02208684 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,01397718 0,02207257 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,01397718 0,02205831 ! response to vitamin GO:0033273 36 20 0,000 0,01397718 0,02204407 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,01397718 0,02202985 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,01397718 0,02201564 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,01397718 0,02200146 ! bile acid metabolic process GO:0008206 34 20 0,000 0,01397718 0,02198729 ! response to alkaloid GO:0043279 38 20 0,000 0,01397718 0,02197314 ! retinoid metabolic process GO:0001523 34 20 0,000 0,01397718 0,02195901 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,01397718 0,0219449 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,01397718 0,0219308 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,01397718 0,02191673 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,01397718 0,02190267 ! actin filament bundle formation GO:0051017 47 20 0,000 0,01397718 0,02188863 ! body fluid secretion GO:0007589 33 20 0,000 0,01397718 0,02187461 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,01397718 0,0218606 ! peptide secretion GO:0002790 38 20 0,000 0,01397718 0,02184662 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,01397718 0,02183265 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,01397718 0,0218187 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,01397718 0,02180476 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,01397718 0,02179085 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,01397718 0,02177695 ! cell-cell junction organization GO:0045216 43 20 0,000 0,01397718 0,02176307 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,01397718 0,02174921 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,01397718 0,02173537 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,01397718 0,02172154 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,01397718 0,02170773 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,01397718 0,02169394 ! regulation of glucose import GO:0046324 30 20 0,000 0,01397718 0,02168017 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,01397718 0,02166641 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,01397718 0,02165267 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,01397718 0,02163895 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,01397718 0,02162524 ! regulation of cell killing GO:0031341 46 21 0,000 0,0146711 0,02268449 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,0146711 0,02267014 ! hormone secretion GO:0046879 39 21 0,000 0,0146711 0,02265581 ! lipid phosphorylation GO:0046834 43 21 0,000 0,0146711 0,0226415 ! cAMP metabolic process GO:0046058 41 21 0,000 0,0146711 0,0226272 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,0146711 0,02261293 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,0146711 0,02259867 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,0146711 0,02258443 ! ovarian follicle development GO:0001541 39 21 0,000 0,0146711 0,02257021 ! smooth muscle contraction GO:0006939 48 21 0,000 0,0146711 0,022556 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,0146711 0,02254182 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,0146711 0,02252765 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,0146711 0,0225135 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,0146711 0,02249937 ! plasma membrane fusion GO:0045026 33 21 0,000 0,0146711 0,02248525 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,0146711 0,02247115 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,0146711 0,02245707 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,0146711 0,02244301 ! sensory perception of pain GO:0019233 33 21 0,000 0,0146711 0,02242897 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,0146711 0,02241494 ! diencephalon development GO:0021536 36 21 0,000 0,0146711 0,02240093 ! collagen fibril organization GO:0030199 62 21 0,000 0,0146711 0,02238694 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,0146711 0,02237297 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,0146711 0,02235901 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,0146711 0,02234507 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,0146711 0,02233115 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,0146711 0,02231724 ! collagen catabolic process GO:0030574 29 21 0,000 0,0146711 0,02230335 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,0146711 0,02228948 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,0146711 0,02227563 ! sperm-egg recognition GO:0035036 23 21 0,000 0,0146711 0,0222618 ! actin filament-based movement GO:0030048 47 21 0,000 0,0146711 0,02224798 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,0146711 0,02223418 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,01536454 0,02327066 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,01536454 0,02325624 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,01536454 0,02324184 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,01536454 0,02322746 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,01536454 0,0232131 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,01536454 0,02319875 ! microtubule-based transport GO:0010970 59 22 0,000 0,01536454 0,02318442 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,01536454 0,02317011 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,01536454 0,02315581 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,01536454 0,02314154 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,01536454 0,02312728 ! cellular response to starvation GO:0009267 37 22 0,000 0,01536454 0,02311304 ! vacuolar transport GO:0007034 41 22 0,000 0,01536454 0,02309882 ! central nervous system neuron development GO:0021954 47 22 0,000 0,01536454 0,02308461 ! fucose metabolic process GO:0006004 44 22 0,000 0,01536454 0,02307042 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,01536454 0,02305625 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,01536454 0,0230421 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,01536454 0,02302796 ! ureteric bud development GO:0001657 50 22 0,000 0,01536454 0,02301384 ! cell aging GO:0007569 48 22 0,000 0,01536454 0,02299974 ! stem cell differentiation GO:0048863 57 22 0,000 0,01536454 0,02298566 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,01536454 0,02297159 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,01536454 0,02295754 ! cytolysis GO:0019835 27 22 0,000 0,01536454 0,02294351 ! renal system process GO:0003014 42 22 0,000 0,01536454 0,02292949 ! vasodilation GO:0042311 40 22 0,000 0,01536454 0,02291549 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,01536454 0,02290151 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,01536454 0,02288755 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,01536454 0,0228736 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,01536454 0,02285967 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,01536454 0,02284576 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,01536454 0,02283186 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,01536454 0,02281798 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,01536454 0,02280412 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,01536454 0,02279027 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,01536454 0,02277644 ! sarcomere organization GO:0045214 32 22 0,000 0,01536454 0,02276263 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,01536454 0,02274883 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,01536454 0,02273505 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,01536454 0,02272129 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,01536454 0,02270755 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,01536454 0,02269382 ! gut development GO:0048565 44 22 0,000 0,01536454 0,02268011 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,01536454 0,02266641 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,01536454 0,02265273 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,01536454 0,02263907 ! protein stabilization GO:0050821 41 22 0,000 0,01536454 0,02262542 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,01605752 0,02363164 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,01605752 0,02361741 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,01605752 0,0236032 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,01605752 0,02358901 ! gluconeogenesis GO:0006094 38 23 0,000 0,01605752 0,02357483 ! glycerol metabolic process GO:0006071 40 23 0,000 0,01605752 0,02356067 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,01605752 0,02354653 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,01605752 0,0235324 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,01605752 0,02351829 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,01605752 0,0235042 ! regeneration GO:0031099 42 23 0,000 0,01605752 0,02349013 ! axis specification GO:0009798 43 23 0,000 0,01605752 0,02347607 ! visual behavior GO:0007632 46 23 0,000 0,01605752 0,02346203 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,01605752 0,02344801 ! response to ethanol GO:0045471 47 23 0,000 0,01605752 0,023434 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,01605752 0,02342001 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,01605752 0,02340604 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,01605752 0,02339208 ! peroxisome organization GO:0007031 43 23 0,000 0,01605752 0,02337814 ! lysosome organization GO:0007040 47 23 0,000 0,01605752 0,02336421 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,01605752 0,02335031 ! vesicle targeting GO:0006903 49 23 0,000 0,01605752 0,02333642 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,01605752 0,02332254 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,01605752 0,02330868 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,01605752 0,02329484 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,01605752 0,02328102 ! DNA modification GO:0006304 36 23 0,000 0,01605752 0,02326721 ! fatty acid transport GO:0015908 47 23 0,000 0,01605752 0,02325342 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,01605752 0,02323964 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,01605752 0,02322588 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,01605752 0,02321214 ! hormone transport GO:0009914 41 23 0,000 0,01605752 0,02319841 ! cell-cell recognition GO:0009988 28 23 0,000 0,01605752 0,0231847 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,01605752 0,02317101 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,01605752 0,02315733 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,01605752 0,02314367 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,01675003 0,02412754 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,01675003 0,02411332 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,01675003 0,02409912 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,01675003 0,02408494 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,01675003 0,02407077 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,01675003 0,02405662 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,01675003 0,02404249 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,01675003 0,02402837 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,01675003 0,02401427 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,01675003 0,02400018 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,01675003 0,02398611 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,01675003 0,02397206 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,01675003 0,02395803 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,01675003 0,02394401 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,01675003 0,02393001 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,01675003 0,02391602 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,01675003 0,02390205 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,01675003 0,0238881 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,01675003 0,02387416 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,01675003 0,02386024 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,01675003 0,02384634 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,01675003 0,02383245 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,01675003 0,02381857 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,01675003 0,02380472 ! membrane depolarization GO:0051899 45 24 0,000 0,01675003 0,02379088 ! pallium development GO:0021543 56 24 0,000 0,01675003 0,02377705 ! oogenesis GO:0048477 44 24 0,000 0,01675003 0,02376325 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,01675003 0,02374946 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,01675003 0,02373568 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,01675003 0,02372192 ! platelet activation GO:0030168 41 24 0,000 0,01675003 0,02370818 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,01675003 0,02369445 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,01675003 0,02368074 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,01675003 0,02366704 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,01675003 0,02365336 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,01675003 0,02363969 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,01675003 0,02362605 ! regulation of amine transport GO:0051952 41 24 0,000 0,01675003 0,02361241 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,01675003 0,0235988 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,01744206 0,02455963 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,01744206 0,02454549 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,01744206 0,02453136 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,01744206 0,02451724 ! leukocyte adhesion GO:0007159 55 25 0,000 0,01744206 0,02450314 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,01744206 0,02448906 ! phototransduction GO:0007602 37 25 0,000 0,01744206 0,02447499 ! keratinization GO:0031424 37 25 0,000 0,01744206 0,02446094 ! vasculogenesis GO:0001570 49 25 0,000 0,01744206 0,02444691 ! vacuole organization GO:0007033 49 25 0,000 0,01744206 0,02443289 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,01744206 0,02441889 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,01744206 0,02440491 ! receptor metabolic process GO:0043112 53 25 0,000 0,01744206 0,02439094 ! chromosome condensation GO:0030261 48 25 0,000 0,01744206 0,02437698 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,01744206 0,02436304 ! regulation of behavior GO:0050795 48 25 0,000 0,01744206 0,02434912 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,01744206 0,02433522 ! interaction with host GO:0051701 66 25 0,000 0,01744206 0,02432133 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,01744206 0,02430745 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,01744206 0,02429359 ! immunoglobulin production GO:0002377 62 25 0,000 0,01744206 0,02427975 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,01744206 0,02426593 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,01744206 0,02425211 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,01744206 0,02423832 ! liver development GO:0001889 55 25 0,000 0,01744206 0,02422454 ! protein tetramerization GO:0051262 57 25 0,000 0,01744206 0,02421078 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,01813364 0,02515643 ! myelination GO:0042552 50 26 0,000 0,01813364 0,02514215 ! initiation of viral infection GO:0019059 60 26 0,000 0,01813364 0,02512789 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,01813364 0,02511365 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,01813364 0,02509942 ! molting cycle process GO:0022404 52 26 0,000 0,01813364 0,02508521 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,01813364 0,02507101 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,01813364 0,02505683 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,01813364 0,02504267 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,01813364 0,02502852 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,01813364 0,02501438 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,01813364 0,02500027 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,01813364 0,02498617 ! digestive system process GO:0022600 49 26 0,000 0,01813364 0,02497208 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,01813364 0,02495801 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,01813364 0,02494396 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,01813364 0,02492992 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,01813364 0,0249159 ! osteoblast differentiation GO:0001649 63 26 0,000 0,01813364 0,0249019 ! neural crest cell development GO:0014032 59 26 0,000 0,01813364 0,02488791 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,01813364 0,02487393 ! negative regulation of cell development GO:0010721 83 26 0,000 0,01813364 0,02485997 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,01813364 0,02484603 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,01813364 0,0248321 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,01813364 0,02481819 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,01813364 0,0248043 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,01813364 0,02479042 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,01813364 0,02477655 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,01813364 0,0247627 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,01813364 0,02474887 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,01813364 0,02473505 ! blastocyst development GO:0001824 50 26 0,000 0,01813364 0,02472125 ! telomere organization GO:0032200 46 26 0,000 0,01813364 0,02470746 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,01813364 0,02469369 ! neural tube closure GO:0001843 58 26 0,000 0,01813364 0,02467993 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,01813364 0,02466619 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,01813364 0,02465246 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,01813364 0,02463875 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,01882474 0,02556356 ! embryonic pattern specification GO:0009880 49 27 0,000 0,01882474 0,02554936 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,01882474 0,02553517 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,01882474 0,025521 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,01882474 0,02550685 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,01882474 0,02549271 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,01882474 0,02547858 ! iron ion transport GO:0006826 65 27 0,000 0,01882474 0,02546448 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,01882474 0,02545038 ! superoxide metabolic process GO:0006801 41 27 0,000 0,01882474 0,02543631 ! tube lumen formation GO:0035148 59 27 0,000 0,01882474 0,02542225 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,01882474 0,0254082 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,01882474 0,02539417 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,01882474 0,02538016 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,01882474 0,02536616 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,01882474 0,02535217 ! response to starvation GO:0042594 47 27 0,000 0,01882474 0,02533821 ! response to toxin GO:0009636 49 27 0,000 0,01882474 0,02532425 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,01882474 0,02531032 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,01882474 0,02529639 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,01882474 0,02528249 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,01882474 0,0252686 ! leukocyte proliferation GO:0070661 59 27 0,000 0,01882474 0,02525472 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,01882474 0,02524086 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,01951538 0,02615254 ! neuron fate commitment GO:0048663 52 28 0,000 0,01951538 0,0261382 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,01951538 0,02612388 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,01951538 0,02610957 ! protein amino acid acylation GO:0043543 59 28 0,000 0,01951538 0,02609528 ! vesicle docking GO:0048278 55 28 0,000 0,01951538 0,026081 ! circadian rhythm GO:0007623 56 28 0,000 0,01951538 0,02606674 ! dendrite development GO:0016358 67 28 0,000 0,01951538 0,0260525 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,01951538 0,02603827 ! sperm motility GO:0030317 37 28 0,000 0,01951538 0,02602406 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,01951538 0,02600986 ! base-excision repair GO:0006284 41 28 0,000 0,01951538 0,02599568 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,01951538 0,02598151 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,01951538 0,02596736 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,01951538 0,02595322 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,01951538 0,0259391 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,01951538 0,025925 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,01951538 0,02591091 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,01951538 0,02589683 ! glutathione metabolic process GO:0006749 42 28 0,000 0,01951538 0,02588278 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,01951538 0,02586873 ! lipid oxidation GO:0034440 48 28 0,000 0,01951538 0,0258547 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,01951538 0,02584069 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,01951538 0,02582669 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,02020555 0,02672559 ! translational initiation GO:0006413 66 29 0,000 0,02020555 0,02671113 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,02020555 0,02669668 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,02020555 0,02668225 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,02020555 0,02666783 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,02020555 0,02665343 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,02020555 0,02663905 ! primary neural tube formation GO:0014020 61 29 0,000 0,02020555 0,02662468 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,02020555 0,02661033 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,02020555 0,02659599 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,02020555 0,02658167 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,02020555 0,02656736 ! somitogenesis GO:0001756 52 29 0,000 0,02020555 0,02655307 ! synaptogenesis GO:0007416 46 29 0,000 0,02020555 0,0265388 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,02020555 0,02652454 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,02020555 0,02651029 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,02020555 0,02649606 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,02020555 0,02648185 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,02089526 0,0273711 ! phenol metabolic process GO:0018958 56 30 0,000 0,02089526 0,02735644 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,02089526 0,02734178 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,02089526 0,02732715 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,02089526 0,02731252 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,02089526 0,02729792 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,02089526 0,02728333 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,02089526 0,02726875 ! acute-phase response GO:0006953 50 30 0,000 0,02089526 0,0272542 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,02089526 0,02723965 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,02089526 0,02722512 ! myofibril assembly GO:0030239 50 30 0,000 0,02089526 0,02721061 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,02089526 0,02719612 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,02089526 0,02718163 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,02089526 0,02716717 ! cell fate determination GO:0001709 64 30 0,000 0,02089526 0,02715272 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,02089526 0,02713828 ! phospholipid transport GO:0015914 65 30 0,000 0,02089526 0,02712386 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,02089526 0,02710946 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,02089526 0,02709507 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,02089526 0,02708069 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,02089526 0,02706634 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,02089526 0,02705199 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,02089526 0,02703766 ! regulation of coagulation GO:0050818 52 30 0,000 0,02089526 0,02702335 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,02158449 0,02789996 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,02158449 0,0278852 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,02158449 0,02787046 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,02158449 0,02785574 ! cell junction assembly GO:0034329 85 31 0,000 0,02158449 0,02784103 ! regulation of innate immune response GO:0045088 57 31 0,000 0,02158449 0,02782634 ! ovulation cycle process GO:0022602 55 31 0,000 0,02158449 0,02781167 ! peptide transport GO:0015833 60 31 0,000 0,02158449 0,027797 ! male gonad development GO:0008584 56 31 0,000 0,02158449 0,02778236 ! iron ion homeostasis GO:0055072 60 31 0,000 0,02158449 0,02776773 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,02158449 0,02775311 ! detection of light stimulus GO:0009583 44 31 0,000 0,02158449 0,02773852 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,02158449 0,02772393 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,02158449 0,02770936 ! natural killer cell activation GO:0030101 50 31 0,000 0,02158449 0,02769481 ! ensheathment of neurons GO:0007272 64 31 0,000 0,02158449 0,02768027 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,02158449 0,02766575 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,02158449 0,02765124 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,02158449 0,02763675 ! eye morphogenesis GO:0048592 65 31 0,000 0,02158449 0,02762227 ! response to heat GO:0009408 54 31 0,000 0,02158449 0,02760781 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,02158449 0,02759336 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,02227327 0,02845899 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,02227327 0,02844411 ! collagen metabolic process GO:0032963 49 32 0,000 0,02227327 0,02842925 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,02227327 0,02841441 ! spindle organization GO:0007051 50 32 0,000 0,02227327 0,02839958 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,02227327 0,02838476 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,02227327 0,02836996 ! metanephros development GO:0001656 81 32 0,000 0,02227327 0,02835518 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,02227327 0,02834041 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,02227327 0,02832566 ! muscle cell development GO:0055001 52 32 0,000 0,02227327 0,02831092 ! mesoderm formation GO:0001707 73 32 0,000 0,02227327 0,0282962 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,02227327 0,02828149 ! ovulation cycle GO:0042698 57 32 0,000 0,02227327 0,0282668 ! peripheral nervous system development GO:0007422 68 32 0,000 0,02227327 0,02825212 ! BMP signaling pathway GO:0030509 71 32 0,000 0,02227327 0,02823746 ! hindbrain development GO:0030902 65 32 0,000 0,02227327 0,02822282 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,02227327 0,02820819 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,02227327 0,02819357 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,02227327 0,02817897 ! gene silencing GO:0016458 71 32 0,000 0,02227327 0,02816438 ! regulation of pH GO:0006885 56 33 0,000 0,02296157 0,02901972 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,02296157 0,02900472 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,02296157 0,02898973 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,02296157 0,02897475 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,02296157 0,0289598 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,02296157 0,02894485 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,02296157 0,02892993 ! response to ionizing radiation GO:0010212 74 33 0,000 0,02296157 0,02891501 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,02296157 0,02890012 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,02296157 0,02888523 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,02296157 0,02887037 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,02296157 0,02885552 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,02296157 0,02884068 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,02296157 0,02882586 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,02296157 0,02881106 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,02364942 0,02965889 ! glial cell differentiation GO:0010001 67 34 0,000 0,02364942 0,02964368 ! post-embryonic development GO:0009791 76 34 0,000 0,02364942 0,02962847 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,02364942 0,02961329 ! cholesterol transport GO:0030301 62 34 0,000 0,02364942 0,02959812 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,02364942 0,02958296 ! spliceosome assembly GO:0000245 75 34 0,000 0,02364942 0,02956782 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,02364942 0,0295527 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,02364942 0,02953759 ! formation of primary germ layer GO:0001704 76 34 0,000 0,02364942 0,0295225 ! cell fate specification GO:0001708 56 34 0,000 0,02364942 0,02950742 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,02364942 0,02949235 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,02364942 0,02947731 ! adult locomotory behavior GO:0008344 62 34 0,000 0,02364942 0,02946228 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,02364942 0,02944726 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,02433679 0,03028772 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,02433679 0,03027229 ! negative regulation of secretion GO:0051048 68 35 0,000 0,02433679 0,03025689 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,02433679 0,0302415 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,02433679 0,03022612 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,02433679 0,03021076 ! membrane docking GO:0022406 69 35 0,000 0,02433679 0,03019542 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,02433679 0,03018009 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,02433679 0,03016478 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,02433679 0,03014949 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,02433679 0,0301342 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,02433679 0,03011894 ! ceramide metabolic process GO:0006672 72 35 0,000 0,02433679 0,03010369 ! telencephalon development GO:0021537 81 35 0,000 0,02433679 0,03008845 ! sterol transport GO:0015918 63 35 0,000 0,02433679 0,03007323 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,02433679 0,03005803 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,02433679 0,03004284 ! placenta development GO:0001890 53 35 0,000 0,02433679 0,03002767 ! vesicle localization GO:0051648 70 35 0,000 0,02433679 0,03001251 ! regulation of muscle development GO:0048634 82 36 0,000 0,02502371 0,03084405 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,02502371 0,0308285 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,02502371 0,03081296 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,02502371 0,03079744 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,02502371 0,03078193 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,02502371 0,03076644 ! positive regulation of cell development GO:0010720 85 36 0,000 0,02502371 0,03075096 ! protein targeting to membrane GO:0006612 75 36 0,000 0,02502371 0,0307355 ! regulation of proteolysis GO:0030162 77 36 0,000 0,02502371 0,03072006 ! aerobic respiration GO:0009060 56 36 0,000 0,02502371 0,03070463 ! cytokine production GO:0001816 68 36 0,000 0,02502371 0,03068921 ! embryonic organ development GO:0048568 67 36 0,000 0,02502371 0,03067381 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,02502371 0,03065843 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,02502371 0,03064306 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,02571015 0,03146789 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,02571015 0,03145213 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,02571015 0,03143639 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,02571015 0,03142066 ! sister chromatid segregation GO:0000819 65 37 0,000 0,02571015 0,03140495 ! odontogenesis GO:0042476 74 37 0,000 0,02571015 0,03138926 ! actomyosin structure organization GO:0031032 68 37 0,000 0,02571015 0,03137358 ! cell junction organization GO:0034330 96 37 0,000 0,02571015 0,03135792 ! tissue remodeling GO:0048771 78 37 0,000 0,02571015 0,03134227 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,02571015 0,03132664 ! female gonad development GO:0008585 71 37 0,000 0,02571015 0,03131102 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,02571015 0,03129542 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,02571015 0,03127983 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,02571015 0,03126426 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,02571015 0,03124871 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,02639614 0,03206652 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,02639614 0,03205058 ! meiosis I GO:0007127 74 38 0,000 0,02639614 0,03203466 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,02639614 0,03201875 ! organic anion transport GO:0015711 82 38 0,000 0,02639614 0,03200286 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,02639614 0,03198699 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,02639614 0,03197113 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,02639614 0,03195529 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,02639614 0,03193946 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,02639614 0,03192365 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,02639614 0,03190785 ! regulation of protein stability GO:0031647 77 38 0,000 0,02639614 0,03189207 ! spermatid development GO:0007286 69 38 0,000 0,02639614 0,03187631 ! glycogen metabolic process GO:0005977 63 38 0,000 0,02639614 0,03186056 ! pigment metabolic process GO:0042440 87 38 0,000 0,02639614 0,03184482 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,02639614 0,0318291 ! neural tube formation GO:0001841 79 38 0,000 0,02639614 0,0318134 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,02708166 0,03262352 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,02708166 0,03260744 ! negative regulation of binding GO:0051100 71 39 0,000 0,02708166 0,03259138 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,02708166 0,03257533 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,02708166 0,0325593 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,02708166 0,03254328 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,02708166 0,03252728 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,02708166 0,0325113 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,02708166 0,03249533 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,02708166 0,03247938 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,02708166 0,03246344 ! glucan metabolic process GO:0044042 64 39 0,000 0,02708166 0,03244752 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,02776672 0,033252 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,02776672 0,03323571 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,02776672 0,03321944 ! learning GO:0007612 82 40 0,000 0,02776672 0,03320318 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,02776672 0,03318693 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,02776672 0,0331707 ! lipid homeostasis GO:0055088 75 40 0,000 0,02776672 0,03315449 ! mismatch repair GO:0006298 58 40 0,000 0,02776672 0,03313829 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,02776672 0,03312211 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,02776672 0,03310595 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,02776672 0,0330898 ! mRNA catabolic process GO:0006402 79 41 0,000 0,02845131 0,0338891 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,02845131 0,03387259 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,02845131 0,03385609 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,02845131 0,03383961 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,02845131 0,03382314 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,02845131 0,03380669 ! gliogenesis GO:0042063 91 41 0,000 0,02845131 0,03379025 ! feeding behavior GO:0007631 69 41 0,000 0,02845131 0,03377383 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,02845131 0,03375743 ! mesenchymal cell development GO:0014031 94 41 0,000 0,02845131 0,03374104 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,02845131 0,03372467 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,02845131 0,03370832 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,02845131 0,03369198 ! spermatid differentiation GO:0048515 73 41 0,000 0,02845131 0,03367565 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,02845131 0,03365935 ! RNA modification GO:0009451 64 41 0,000 0,02845131 0,03364305 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,02913544 0,03443536 ! ear morphogenesis GO:0042471 64 42 0,000 0,02913544 0,03441871 ! organic ether metabolic process GO:0018904 59 42 0,000 0,02913544 0,03440207 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,02913544 0,03438545 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,02913544 0,03436885 ! T cell differentiation GO:0030217 93 42 0,000 0,02913544 0,03435226 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,02913544 0,03433569 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,02913544 0,03431913 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,02913544 0,03430259 ! regulation of protein secretion GO:0050708 77 42 0,000 0,02913544 0,03428607 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,02913544 0,03426956 ! cytokinesis GO:0000910 84 42 0,000 0,02913544 0,03425307 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,02913544 0,0342366 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,02981911 0,03502312 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,02981911 0,03500629 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,02981911 0,03498948 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,02981911 0,03497268 ! regulation of tube size GO:0035150 76 43 0,000 0,02981911 0,0349559 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,02981911 0,03493913 ! glucose transport GO:0015758 66 43 0,000 0,02981911 0,03492238 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,02981911 0,03490565 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,02981911 0,03488893 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,02981911 0,03487223 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,02981911 0,03485554 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,02981911 0,03483888 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,02981911 0,03482222 ! segmentation GO:0035282 78 43 0,000 0,02981911 0,03480558 ! ion transmembrane transport GO:0034220 79 43 0,000 0,02981911 0,03478896 ! neuron migration GO:0001764 85 43 0,000 0,02981911 0,03477236 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,02981911 0,03475577 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,03050232 0,03553513 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,03050232 0,03551819 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,03050232 0,03550127 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,03050232 0,03548436 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,03050232 0,03546747 ! hexose transport GO:0008645 68 44 0,000 0,03050232 0,0354506 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,03050232 0,03543374 ! striated muscle contraction GO:0006941 85 44 0,000 0,03050232 0,0354169 ! phagocytosis GO:0006909 105 44 0,000 0,03050232 0,03540008 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,03050232 0,03538327 ! double-strand break repair GO:0006302 85 44 0,000 0,03050232 0,03536647 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,03118506 0,03614094 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,03118506 0,03612381 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,03118506 0,03610669 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,03118506 0,03608958 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,03118506 0,03607249 ! B cell differentiation GO:0030183 124 45 0,000 0,03118506 0,03605542 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,03118506 0,03603837 ! female gamete generation GO:0007292 71 45 0,000 0,03118506 0,03602133 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,03118506 0,0360043 ! polyol metabolic process GO:0019751 77 45 0,000 0,03118506 0,0359873 ! developmental growth GO:0048589 88 45 0,000 0,03118506 0,03597031 ! maintenance of location in cell GO:0051651 101 45 0,000 0,03118506 0,03595333 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,03186735 0,03672261 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,03186735 0,03670529 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,03186735 0,036688 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,03186735 0,03667071 ! leukocyte migration GO:0050900 75 46 0,000 0,03186735 0,03665345 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,03186735 0,0366362 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,03186735 0,03661897 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,03186735 0,03660175 ! pigmentation GO:0043473 103 46 0,000 0,03186735 0,03658455 ! cell growth GO:0016049 90 46 0,000 0,03186735 0,03656737 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,03186735 0,0365502 ! neural tube development GO:0021915 91 47 0,000 0,03254917 0,0373147 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,03254917 0,03729719 ! positive regulation of defense response GO:0031349 88 48 0,000 0,03323053 0,03806009 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,03323053 0,03804226 ! mitochondrial transport GO:0006839 94 48 0,000 0,03323053 0,03802444 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,03323053 0,03800664 ! cellular component disassembly GO:0022411 89 48 0,000 0,03323053 0,03798885 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,03323053 0,03797109 ! endosome transport GO:0016197 127 48 0,000 0,03323053 0,03795333 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,03323053 0,0379356 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,03323053 0,03791788 ! male sex differentiation GO:0046661 93 48 0,000 0,03323053 0,03790018 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,03323053 0,03788249 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,03323053 0,03786482 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,03323053 0,03784717 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,03323053 0,03782953 ! methylation GO:0032259 97 48 0,000 0,03323053 0,03781191 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,03391143 0,03856872 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,03391143 0,03855078 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,03391143 0,03853285 ! JNK cascade GO:0007254 106 49 0,000 0,03391143 0,03851493 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,03391143 0,03849704 ! protein homooligomerization GO:0051260 84 49 0,000 0,03391143 0,03847916 ! regulation of action potential GO:0001508 102 50 0,000 0,03459187 0,03923302 ! regulation of ion transport GO:0043269 86 50 0,000 0,03459187 0,03921482 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,03459187 0,03919663 ! endocrine system development GO:0035270 109 50 0,000 0,03459187 0,03917846 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,03459187 0,0391603 ! activation of caspase activity GO:0006919 95 50 0,000 0,03459187 0,03914217 ! regulation of ossification GO:0030278 123 50 0,000 0,03459187 0,03912404 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,03459187 0,03910594 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,03459187 0,03908785 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,03459187 0,03906978 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,03459187 0,03905173 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,03527185 0,03980098 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,03527185 0,03978261 ! peptide metabolic process GO:0006518 80 51 0,000 0,03527185 0,03976425 ! response to temperature stimulus GO:0009266 84 51 0,000 0,03527185 0,03974591 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,03527185 0,03972758 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,03527185 0,03970927 ! positive regulation of binding GO:0051099 88 52 0,000 0,03595137 0,04045564 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,03595137 0,04043701 ! Notch signaling pathway GO:0007219 111 52 0,000 0,03595137 0,0404184 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,03595137 0,04039981 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,03595137 0,04038124 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,03595137 0,04036268 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,03595137 0,04034414 ! excretion GO:0007588 87 52 0,000 0,03595137 0,04032562 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,03595137 0,04030711 ! histone modification GO:0016570 104 52 0,000 0,03595137 0,04028862 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,03595137 0,04027015 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,03595137 0,04025169 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,03595137 0,04023325 ! amino acid activation GO:0043038 98 52 0,000 0,03595137 0,04021483 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,03663043 0,04095567 ! inner ear development GO:0048839 89 53 0,000 0,03663043 0,04093693 ! chromatin remodeling GO:0006338 122 53 0,000 0,03663043 0,04091822 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,03663043 0,04089951 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,03663043 0,04088083 ! vesicle organization GO:0016050 127 53 0,000 0,03663043 0,04086216 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,03663043 0,04084351 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,03663043 0,04082488 ! cartilage development GO:0051216 99 53 0,000 0,03663043 0,04080626 ! synapse organization GO:0050808 102 53 0,000 0,03663043 0,04078767 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,03730903 0,04152436 ! regulation of translational initiation GO:0006446 87 54 0,000 0,03730903 0,04150545 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,03730903 0,04148656 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,03730903 0,04146768 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,03730903 0,04144882 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,03730903 0,04142998 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,03730903 0,04141116 ! membrane fusion GO:0006944 122 54 0,000 0,03730903 0,04139235 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,03730903 0,04137356 ! covalent chromatin modification GO:0016569 115 54 0,000 0,03730903 0,04135479 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,03730903 0,04133604 ! regulation of cell shape GO:0008360 142 54 0,000 0,03730903 0,0413173 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,03730903 0,04129858 ! RNA catabolic process GO:0006401 103 55 0,000 0,03798717 0,04203019 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,03798717 0,04201116 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,03798717 0,04199216 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,03798717 0,04197316 ! cell recognition GO:0008037 98 55 0,000 0,03798717 0,04195419 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,03798717 0,04193523 ! cell maturation GO:0048469 107 55 0,000 0,03798717 0,04191629 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,03798717 0,04189736 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,03798717 0,04187846 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,03866486 0,04260634 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,03866486 0,04258713 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,03866486 0,04256793 ! regulation of DNA replication GO:0006275 105 56 0,000 0,03866486 0,04254876 ! RNA elongation GO:0006354 90 56 0,000 0,03866486 0,0425296 ! chloride transport GO:0006821 102 57 0,000 0,03934208 0,04325504 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,03934208 0,04323559 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,03934208 0,04321615 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,03934208 0,04319672 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,03934208 0,04317732 ! heart morphogenesis GO:0003007 105 57 0,000 0,03934208 0,04315793 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,03934208 0,04313856 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,03934208 0,0431192 ! regulation of actin filament length GO:0030832 118 58 0,000 0,04001885 0,04384128 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,04001885 0,04382163 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,04001885 0,04380199 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,04001885 0,04378238 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,04001885 0,04376278 ! aging GO:0007568 112 58 0,000 0,04001885 0,0437432 ! gastrulation GO:0007369 122 58 0,000 0,04001885 0,04372364 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,04001885 0,04370409 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,04001885 0,04368456 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,04001885 0,04366505 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,04001885 0,04364556 ! maintenance of location GO:0051235 124 58 0,000 0,04001885 0,04362608 ! establishment of organelle localization GO:0051656 122 59 0,000 0,04069516 0,04434357 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,04137101 0,04505991 ! lipid modification GO:0030258 112 60 0,000 0,04137101 0,04503983 ! DNA catabolic process GO:0006308 94 60 0,000 0,04137101 0,04501977 ! regulation of endocytosis GO:0030100 104 60 0,000 0,04137101 0,04499972 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,04137101 0,0449797 ! adult behavior GO:0030534 104 60 0,000 0,04137101 0,04495969 ! kidney development GO:0001822 133 60 0,000 0,04137101 0,0449397 ! positive regulation of secretion GO:0051047 110 61 0,000 0,04204641 0,04565305 ! regulation of cellular component size GO:0032535 125 61 0,000 0,04204641 0,04563277 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,04204641 0,04561251 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,04204641 0,04559226 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,04204641 0,04557204 ! regulation of heart contraction GO:0008016 123 61 0,000 0,04204641 0,04555183 ! camera-type eye development GO:0043010 126 61 0,000 0,04204641 0,04553164 ! proton transport GO:0015992 117 61 0,000 0,04204641 0,04551146 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,04204641 0,04549131 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,04272135 0,04620108 ! tRNA processing GO:0008033 102 62 0,000 0,04272135 0,04618064 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,04272135 0,04616022 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,04339583 0,04686826 ! regulation of mitosis GO:0007088 112 63 0,000 0,04339583 0,04684755 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,04339583 0,04682686 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,04339583 0,04680618 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,04339583 0,04678553 ! hydrogen transport GO:0006818 121 64 0,000 0,04406985 0,04749124 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,04406985 0,0474703 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,04406985 0,04744938 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,04406985 0,04742848 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,04474342 0,04813218 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,04474342 0,048111 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,04474342 0,04808983 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,04474342 0,04806868 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,04474342 0,04804755 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,04474342 0,04802644 ! ear development GO:0043583 114 66 0,000 0,04541654 0,04872754 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,04541654 0,04870615 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,04541654 0,04868477 ! gonad development GO:0008406 115 66 0,000 0,04541654 0,04866342 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,04541654 0,04864209 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,0460892 0,04934089 ! activation of MAPK activity GO:0000187 124 67 0,000 0,0460892 0,04931927 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,0460892 0,04929768 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,0460892 0,04927611 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,0460892 0,04925455 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,0460892 0,04923301 ! secondary metabolic process GO:0019748 125 67 0,000 0,0460892 0,0492115 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,0460892 0,04919 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,0467614 0,04988563 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,0467614 0,04986386 ! extracellular matrix organization GO:0030198 146 68 0,000 0,0467614 0,0498421 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,0467614 0,04982037 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,0467614 0,04979865 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,0467614 0,04977695 ! regulation of lipase activity GO:0060191 137 68 0,000 0,0467614 0,04975527 ! adaptive immune response GO:0002250 126 68 0,000 0,0467614 0,04973361 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,0467614 0,04971197 ! negative regulation of cell size GO:0045792 144 69 0,000 0,04743315 0,05040417 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,04743315 0,05038225 ! lung development GO:0030324 165 69 0,000 0,04743315 0,05036036 ! urogenital system development GO:0001655 149 69 0,000 0,04743315 0,05033848 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,04743315 0,05031662 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,04743315 0,05029478 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,04743315 0,05027296 ! developmental maturation GO:0021700 128 69 0,000 0,04743315 0,05025116 ! single fertilization GO:0007338 83 69 0,000 0,04743315 0,05022938 ! cell redox homeostasis GO:0045454 114 70 0,000 0,04810444 0,05091818 ! germ cell development GO:0007281 133 70 0,000 0,04810444 0,05089613 ! activation of immune response GO:0002253 120 70 0,000 0,04810444 0,05087409 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,04810444 0,05085208 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,04877528 0,05153893 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,04877528 0,05151665 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,04877528 0,05149439 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,04877528 0,05147215 ! appendage morphogenesis GO:0035107 150 72 0,000 0,04944567 0,05215707 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,04944567 0,05213456 ! respiratory tube development GO:0030323 171 72 0,000 0,04944567 0,05211207 ! actin filament organization GO:0007015 167 72 0,000 0,04944567 0,05208959 ! B cell activation GO:0042113 179 72 0,000 0,04944567 0,05206714 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,04944567 0,05204471 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,04944567 0,0520223 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,04944567 0,0519999 ! appendage development GO:0048736 151 73 0,000 0,0501156 0,05268176 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,0501156 0,0526591 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,0501156 0,05263646 ! regulation of immune effector process GO:0002697 156 73 0,000 0,0501156 0,05261384 ! acute inflammatory response GO:0002526 118 74 0,000 0,05078508 0,0532938 ! amino acid transport GO:0006865 148 74 0,000 0,05078508 0,05327091 ! respiratory system development GO:0060541 175 74 0,000 0,05078508 0,05324805 ! organelle localization GO:0051640 155 74 0,000 0,05078508 0,05322521 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,05145411 0,05390325 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,05145411 0,05388015 ! reproductive structure development GO:0048608 131 75 0,000 0,05145411 0,05385706 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,05145411 0,053834 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,05145411 0,05381095 ! eye development GO:0001654 155 75 0,000 0,05145411 0,05378793 ! axon guidance GO:0007411 162 75 0,000 0,05145411 0,05376492 ! rhythmic process GO:0048511 142 75 0,000 0,05145411 0,05374194 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,05212268 0,05441697 ! learning or memory GO:0007611 161 76 0,000 0,05212268 0,05439373 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,05212268 0,0543705 ! regulation of blood pressure GO:0008217 134 76 0,000 0,05212268 0,0543473 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,05212268 0,05432411 ! amine catabolic process GO:0009310 136 77 0,000 0,0527908 0,05499699 ! neurotransmitter transport GO:0006836 142 77 0,000 0,0527908 0,05497354 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,0527908 0,05495012 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,0527908 0,05492672 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,0527908 0,05490333 ! regulation of catabolic process GO:0009894 173 77 0,000 0,0527908 0,05487997 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,05345847 0,05555043 ! antigen processing and presentation GO:0019882 117 78 0,000 0,05345847 0,05552681 ! fertilization GO:0009566 99 78 0,000 0,05345847 0,05550321 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,05345847 0,05547963 ! blood coagulation GO:0007596 151 79 0,000 0,05412569 0,05614822 GO:0050817|coagulation, ! steroid biosynthetic process GO:0006694 146 79 0,000 0,05412569 0,05612439 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,05412569 0,05610058 ! protein oligomerization GO:0051259 149 79 0,000 0,05412569 0,05607679 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,05412569 0,05605301 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,05479246 0,05671948 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,05479246 0,05669546 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,05479246 0,05667145 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,05479246 0,05664747 ! meiosis GO:0007126 143 81 0,000 0,05545877 0,05731209 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,05545877 0,05728786 ! response to hypoxia GO:0001666 178 81 0,000 0,05545877 0,05726364 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,05545877 0,05723945 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,05612464 0,05790223 ! protein import into nucleus GO:0006606 174 82 0,000 0,05612464 0,05787779 ! meiotic cell cycle GO:0051321 144 82 0,000 0,05612464 0,05785337 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,05679005 0,05851459 ! exocytosis GO:0006887 153 83 0,000 0,05679005 0,05848992 ! response to drug GO:0042493 149 83 0,000 0,05679005 0,05846527 ! response to oxygen levels GO:0070482 183 83 0,000 0,05679005 0,05844064 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,05679005 0,05841604 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,05679005 0,05839145 ! nuclear import GO:0051170 177 83 0,000 0,05679005 0,05836689 ! inorganic anion transport GO:0015698 156 83 0,000 0,05679005 0,05834234 ! T cell activation GO:0042110 189 84 0,000 0,05745501 0,05900067 ! response to nutrient GO:0007584 135 84 0,000 0,05745501 0,05897588 ! digestion GO:0007586 130 84 0,000 0,05745501 0,05895111 ! hemostasis GO:0007599 165 85 0,000 0,05811952 0,05960789 ! negative regulation of transport GO:0051051 164 85 0,000 0,05811952 0,05958288 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,05811952 0,05955789 ! negative regulation of growth GO:0045926 168 85 0,000 0,05811952 0,05953291 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,05811952 0,05950796 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,05811952 0,05948303 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,05811952 0,05945812 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,05811952 0,05943323 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,05878359 0,06008716 ! regulation of lyase activity GO:0051339 169 86 0,000 0,05878359 0,06006203 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,05878359 0,06003692 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,0594472 0,06068931 ! nucleosome assembly GO:0006334 126 87 0,000 0,0594472 0,06066396 ! regulation of protein transport GO:0051223 165 87 0,000 0,0594472 0,06063863 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,06011037 0,06128949 ! amine biosynthetic process GO:0009309 146 88 0,000 0,06011037 0,06126392 ! sensory perception of smell GO:0007608 117 88 0,000 0,06011037 0,06123837 ! chromatin assembly GO:0031497 128 88 0,000 0,06011037 0,06121285 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,06011037 0,06118734 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,06077308 0,06183617 ! regulation of DNA binding GO:0051101 167 89 0,000 0,06077308 0,06181042 ! tube morphogenesis GO:0035239 194 89 0,000 0,06077308 0,0617847 ! cellular defense response GO:0006968 123 89 0,000 0,06077308 0,061759 ! protein localization in nucleus GO:0034504 192 89 0,000 0,06077308 0,06173332 ! regulation of neurological system process GO:0031644 175 89 0,000 0,06077308 0,06170766 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,06143535 0,0623542 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,06143535 0,0623283 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,06209717 0,06297359 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,06209717 0,06294746 ! gland development GO:0048732 220 91 0,000 0,06209717 0,06292135 ! defense response to bacterium GO:0042742 112 91 0,000 0,06209717 0,06289526 ! bone development GO:0060348 206 92 0,000 0,06275854 0,06353879 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,06275854 0,06351247 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,06341946 0,06415476 ! amine transport GO:0015837 181 93 0,000 0,06341946 0,0641282 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,06341946 0,06410167 ! vitamin metabolic process GO:0006766 153 93 0,000 0,06341946 0,06407516 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,06407994 0,0647157 ! female pregnancy GO:0007565 166 94 0,000 0,06407994 0,06468896 ! sterol metabolic process GO:0016125 166 94 0,000 0,06407994 0,06466224 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,06407994 0,06463554 ! regulation of membrane potential GO:0042391 179 94 0,000 0,06407994 0,06460887 ! regulation of defense response GO:0031347 171 95 0,000 0,06473996 0,06524741 ! nucleosome organization GO:0034728 143 95 0,000 0,06473996 0,06522051 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,06473996 0,06519362 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,06473996 0,06516676 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,06473996 0,06513992 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,06473996 0,0651131 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,06473996 0,06508631 ! sex differentiation GO:0007548 171 96 0,000 0,06539954 0,06572237 ! regulation of T cell activation GO:0050863 175 96 0,000 0,06539954 0,06569535 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,06605868 0,06633019 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,06605868 0,06630294 ! transcription initiation GO:0006352 171 97 0,000 0,06605868 0,06627571 ! regulation of protein localization GO:0032880 188 97 0,000 0,06605868 0,0662485 ! leukocyte differentiation GO:0002521 232 98 0,000 0,06671737 0,06688163 ! forebrain development GO:0030900 210 98 0,000 0,06671737 0,0668542 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,06671737 0,06682679 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,06803341 0,06811706 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,06803341 0,06808915 ! positive regulation of immune response GO:0050778 175 100 0,000 0,06803341 0,06806127 ! hormone metabolic process GO:0042445 171 100 0,000 0,06803341 0,06803341