pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/103-0-real-Zhang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle organization GO:0007051 37 30 3,000 1,402E-07 3,224E-04 ! microtubule cytoskeleton organization GO:0000226 120 84 4,000 2,046E-07 2,352E-04 ! mitotic spindle organization GO:0007052 15 11 2,000 6,019E-07 4,615E-04 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 3,000 6,222E-07 3,578E-04 ! nuclear export GO:0051168 69 48 3,000 9,757E-07 4,488E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 1,249E-06 4,788E-04 ! protein export from nucleus GO:0006611 24 16 2,000 2,032E-06 6,677E-04 ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 1,021E-05 2,936E-03 ! interphase GO:0051325 159 88 3,000 1,119E-05 2,86E-03 ! establishment of RNA localization GO:0051236 128 88 3,000 1,119E-05 2,574E-03 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! RNA localization GO:0006403 135 91 3,000 1,278E-05 2,673E-03 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 3,000 1,58E-05 3,029E-03 ! RNA export from nucleus GO:0006405 44 33 2,000 1,944E-05 3,439E-03 ! androgen receptor signaling pathway GO:0030521 54 33 2,000 1,944E-05 3,194E-03 ! negative regulation of protein ubiquitination GO:0031397 7 5 1,000 2,466E-05 3,782E-03 ! regulation of centrosome cycle GO:0046605 7 5 1,000 2,466E-05 3,546E-03 ! base conversion or substitution editing GO:0016553 5 5 1,000 2,466E-05 3,337E-03 ! positive regulation of Rho GTPase activity GO:0032321 9 5 1,000 2,466E-05 3,152E-03 ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 3,494E-05 4,229E-03 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 3,696E-05 4,25E-03 ! microtubule nucleation GO:0007020 10 6 1,000 3,696E-05 4,048E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 5,169E-05 5,404E-03 ! regulation of focal adhesion formation GO:0051893 17 7 1,000 5,169E-05 5,169E-03 ! response to UV GO:0009411 75 46 2,000 5,334E-05 5,112E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 6,886E-05 6,335E-03 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 6,886E-05 6,091E-03 ! keratinocyte proliferation GO:0043616 12 8 1,000 6,886E-05 5,865E-03 ! positive regulation of Ras GTPase activity GO:0032320 20 8 1,000 6,886E-05 5,656E-03 ! positive regulation of GTPase activity GO:0043547 21 9 1,000 8,844E-05 7,014E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 1,000 8,844E-05 6,78E-03 ! regulation of stress fiber formation GO:0051492 20 9 1,000 8,844E-05 6,562E-03 ! negative regulation of protein kinase activity GO:0006469 99 57 2,000 1,016E-04 7,303E-03 ! negative regulation of kinase activity GO:0033673 100 58 2,000 1,07E-04 7,46E-03 ! steroid hormone receptor signaling pathway GO:0030518 96 58 2,000 1,07E-04 7,24E-03 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,104E-04 7,258E-03 ! regulation of phosphatase activity GO:0010921 21 10 1,000 1,104E-04 7,056E-03 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 1,000 1,104E-04 6,865E-03 ! regulation of actin filament bundle formation GO:0032231 21 10 1,000 1,104E-04 6,685E-03 ! negative regulation of transferase activity GO:0051348 105 61 2,000 1,244E-04 7,339E-03 ! regulation of Rho GTPase activity GO:0032319 18 11 1,000 1,348E-04 7,754E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 2,000 1,37E-04 7,686E-03 ! regulation of caspase activity GO:0043281 97 65 2,000 1,504E-04 8,235E-03 ! positive regulation of cell growth GO:0030307 16 12 1,000 1,617E-04 8,647E-03 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 1,646E-04 8,603E-03 ! regulation of Ras GTPase activity GO:0032318 110 68 2,000 1,72E-04 8,791E-03 ! regulation of peptidase activity GO:0052547 106 72 2,000 2,038E-04 0,01018991 ! regulation of S phase GO:0033261 18 14 1,000 2,225E-04 0,01088598 ! gene silencing by RNA GO:0031047 20 14 1,000 2,225E-04 0,01065919 ! negative regulation of caspase activity GO:0043154 20 14 1,000 2,225E-04 0,01044166 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 2,225E-04 0,01023283 ! response to unfolded protein GO:0006986 99 76 2,000 2,392E-04 0,01078735 ! positive regulation of cell size GO:0045793 20 15 1,000 2,564E-04 0,01134174 ! skin development GO:0043588 25 15 1,000 2,564E-04 0,01112775 ! neuron recognition GO:0008038 22 15 1,000 2,564E-04 0,01092168 ! regulation of protein ubiquitination GO:0031396 19 15 1,000 2,564E-04 0,0107231 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 2,564E-04 0,01053162 ! regulation of GTPase activity GO:0043087 129 80 2,000 2,784E-04 0,01123193 ! regulation of cell cycle process GO:0010564 122 81 2,000 2,888E-04 0,01145055 ! response to protein stimulus GO:0051789 111 81 2,000 2,888E-04 0,01125648 ! cellular response to unfolded protein GO:0034620 19 16 1,000 2,928E-04 0,0112226 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of dephosphorylation GO:0035303 33 16 1,000 2,928E-04 0,01103862 ! negative regulation of translation GO:0017148 22 16 1,000 2,928E-04 0,01086058 ! negative regulation of peptidase activity GO:0010466 23 17 1,000 3,315E-04 0,01210128 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 3,725E-04 0,01338795 ! protein import into nucleus, docking GO:0000059 30 19 1,000 4,159E-04 0,01471821 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 4,159E-04 0,01449521 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 4,159E-04 0,01427886 ! apoptotic nuclear changes GO:0030262 24 19 1,000 4,159E-04 0,01406888 ! regulation of cytoskeleton organization GO:0051493 154 93 2,000 4,336E-04 0,01445222 ! regulation of ARF GTPase activity GO:0032312 31 20 1,000 4,617E-04 0,01517042 ! positive regulation of B cell activation GO:0050871 31 20 1,000 4,617E-04 0,01495675 ! response to light stimulus GO:0009416 153 96 2,000 4,759E-04 0,01520081 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 5,098E-04 0,01606232 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 5,098E-04 0,01584526 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 5,098E-04 0,01563399 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 5,098E-04 0,01542828 ! regulation of translation GO:0006417 151 100 2,000 5,362E-04 0,01601723 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 5,602E-04 0,01651958 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 5,602E-04 0,01631047 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of cell adhesion GO:0045785 37 23 1,000 6,13E-04 0,01762309 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 6,13E-04 0,01740552 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 6,13E-04 0,01719326 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 6,13E-04 0,01698611 ! fat cell differentiation GO:0045444 37 24 1,000 6,68E-04 0,01829158 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 7,254E-04 0,01962879 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of protein modification process GO:0031400 50 26 1,000 7,851E-04 0,02099646 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 7,851E-04 0,02075512 ! gene silencing GO:0016458 41 27 1,000 8,471E-04 0,02213888 ! regulation of B cell activation GO:0050864 42 28 1,000 9,113E-04 0,02355066 ! regulation of microtubule-based process GO:0032886 58 30 1,000 1,047E-03 0,0267478 ! response to heat GO:0009408 41 30 1,000 1,047E-03 0,02645387 ! RNA modification GO:0009451 40 31 1,000 1,118E-03 0,02794323 ! regulation of ARF protein signal transduction GO:0032012 51 32 1,000 1,191E-03 0,02945645 ! nucleus organization GO:0006997 49 33 1,000 1,267E-03 0,03099259 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 1,267E-03 0,03066635 ! keratinocyte differentiation GO:0030216 47 35 1,000 1,425E-03 0,03413014 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 1,425E-03 0,03377828 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 1,000 1,767E-03 0,04147304 ! response to calcium ion GO:0051592 58 40 1,000 1,858E-03 0,04317214 ! epidermal cell differentiation GO:0009913 53 40 1,000 1,858E-03 0,04274042 ! cellular component disassembly GO:0022411 64 42 1,000 2,047E-03 0,04661943 ! activation of caspase activity GO:0006919 65 43 1,000 2,145E-03 0,04836635 ! response to insulin stimulus GO:0032868 63 43 1,000 2,145E-03 0,04789677 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 2,245E-03 0,04964598 ! positive regulation of cell cycle GO:0045787 77 45 1,000 2,347E-03 0,05140943 ! regulation of translational initiation GO:0006446 64 45 1,000 2,347E-03 0,05092444 ! cell recognition GO:0008037 58 45 1,000 2,347E-03 0,05044851 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 2,558E-03 0,05446785 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of caspase activity GO:0043280 72 48 1,000 2,666E-03 0,05625895 GO:0010952|positive regulation of peptidase activity, ! response to temperature stimulus GO:0009266 62 48 1,000 2,666E-03 0,0557475 ! positive regulation of growth GO:0045927 67 50 1,000 2,89E-03 0,0598775 ! regulation of protein catabolic process GO:0042176 77 51 1,000 3,005E-03 0,06170404 ! positive regulation of organelle organization GO:0010638 82 51 1,000 3,005E-03 0,06115798 ! regulation of mitosis GO:0007088 84 54 1,000 3,362E-03 0,06783736 GO:0051783|regulation of nuclear division, ! DNA catabolic process GO:0006308 67 54 1,000 3,362E-03 0,06724747 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 3,611E-03 0,07160426 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 3,739E-03 0,07350117 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 4,27E-03 0,08323402 ! negative regulation of cell growth GO:0030308 106 62 1,000 4,408E-03 0,08520157 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 4,408E-03 0,08449156 ! negative regulation of cell size GO:0045792 108 64 1,000 4,69E-03 0,08915604 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 4,69E-03 0,08842525 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 4,69E-03 0,08770635 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 4,835E-03 0,08967236 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 4,835E-03 0,08895498 ! regulation of actin filament-based process GO:0032970 99 66 1,000 4,981E-03 0,090917 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 4,981E-03 0,09020111 ! positive regulation of ligase activity GO:0051351 99 69 1,000 5,431E-03 0,09759346 ! response to metal ion GO:0010038 103 70 1,000 5,586E-03 0,09958677 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 5,586E-03 0,09882071 ! regulation of catabolic process GO:0009894 106 70 1,000 5,586E-03 0,09806636 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 5,742E-03 0,10004565 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 5,9E-03 0,10202969 GO:0045937|positive regulation of phosphate metabolic process, ! mitochondrion organization GO:0007005 104 73 1,000 6,06E-03 0,10401825 ! protein import into nucleus GO:0006606 118 74 1,000 6,222E-03 0,10601113 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 6,222E-03 0,10523164 ! response to inorganic substance GO:0010035 115 75 1,000 6,387E-03 0,10721975 ! negative regulation of growth GO:0045926 123 75 1,000 6,387E-03 0,1064428 ! regulation of ligase activity GO:0051340 114 75 1,000 6,387E-03 0,10567702 ! nuclear import GO:0051170 121 75 1,000 6,387E-03 0,10492218 ! positive regulation of protein modification process GO:0031401 107 78 1,000 6,891E-03 0,11240456 ! cellular respiration GO:0045333 107 79 1,000 7,063E-03 0,11439918 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 7,237E-03 0,11639719 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 1,000 7,237E-03 0,11558888 ! mRNA transport GO:0051028 121 81 1,000 7,413E-03 0,11758188 ! positive regulation of cell activation GO:0050867 120 81 1,000 7,413E-03 0,11677652 GO:0002696|positive regulation of leukocyte activation, ! regulation of cell adhesion GO:0030155 159 83 1,000 7,77E-03 0,12157715 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 7,984E-03 0,12406846 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 7,984E-03 0,12323579 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 7,984E-03 0,12241422 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 7,984E-03 0,12160353 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 7,984E-03 0,1208035 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 7,984E-03 0,12001394 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 7,984E-03 0,11923463 ! sleep GO:0030431 11 5 0,000 7,984E-03 0,11846537 ! negative regulation of bone resorption GO:0045779 10 5 0,000 7,984E-03 0,11770598 ! nucleotide-sugar transport GO:0015780 8 5 0,000 7,984E-03 0,11695626 ! regulation of interferon-beta production GO:0032648 5 5 0,000 7,984E-03 0,11621603 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 7,984E-03 0,11548511 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 7,984E-03 0,11476333 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 7,984E-03 0,11405051 ! tongue development GO:0043586 6 5 0,000 7,984E-03 0,1133465 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 7,984E-03 0,11265112 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 7,984E-03 0,11196422 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 7,984E-03 0,11128565 ! cobalt ion transport GO:0006824 9 5 0,000 7,984E-03 0,11061526 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 7,984E-03 0,10995289 ! SMAD protein complex assembly GO:0007183 9 5 0,000 7,984E-03 0,10929841 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 7,984E-03 0,10865167 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 7,984E-03 0,10801254 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 7,984E-03 0,10738089 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 7,984E-03 0,10675658 ! embryonic camera-type eye development GO:0031076 8 5 0,000 7,984E-03 0,10613949 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 7,984E-03 0,1055295 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 7,984E-03 0,10492647 ! adaptation of signaling pathway GO:0022401 7 5 0,000 7,984E-03 0,1043303 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 7,984E-03 0,10374086 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 7,984E-03 0,10315805 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 7,984E-03 0,10258175 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 7,984E-03 0,10201185 ! positive regulation of histone modification GO:0031058 5 5 0,000 7,984E-03 0,10144825 ! malate metabolic process GO:0006108 7 5 0,000 7,984E-03 0,10089084 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 7,984E-03 0,10033952 ! behavioral response to pain GO:0048266 7 5 0,000 7,984E-03 0,0997942 ! clathrin coat assembly GO:0048268 11 5 0,000 7,984E-03 0,09925477 ! phototransduction, visible light GO:0007603 6 5 0,000 7,984E-03 0,09872114 ! regulation of dopamine uptake GO:0051584 9 5 0,000 7,984E-03 0,09819322 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 7,984E-03 0,09767092 ! mating behavior GO:0007617 6 5 0,000 7,984E-03 0,09715414 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 7,984E-03 0,0966428 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 7,984E-03 0,09613682 ! rhythmic behavior GO:0007622 12 5 0,000 7,984E-03 0,09563611 ! copulation GO:0007620 7 5 0,000 7,984E-03 0,09514058 ! glial cell fate commitment GO:0021781 12 5 0,000 7,984E-03 0,09465017 ! protein maturation by protein folding GO:0022417 12 5 0,000 7,984E-03 0,09416478 ! embryonic hemopoiesis GO:0035162 10 5 0,000 7,984E-03 0,09368435 ! regulation of potassium ion transport GO:0043266 9 5 0,000 7,984E-03 0,09320879 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 7,984E-03 0,09273804 ! apoptotic cell clearance GO:0043277 13 5 0,000 7,984E-03 0,09227202 ! lipoprotein particle clearance GO:0034381 9 5 0,000 7,984E-03 0,09181066 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 7,984E-03 0,09135389 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 7,984E-03 0,09090165 ! response to protozoan GO:0001562 9 5 0,000 7,984E-03 0,09045385 ! positive regulation of glycolysis GO:0045821 11 5 0,000 7,984E-03 0,09001045 ! lymph vessel development GO:0001945 7 5 0,000 7,984E-03 0,08957138 ! endochondral ossification GO:0001958 12 5 0,000 7,984E-03 0,08913657 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 7,984E-03 0,08870595 ! parathyroid gland development GO:0060017 8 5 0,000 7,984E-03 0,08827948 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 7,984E-03 0,08785709 ! anagen GO:0042640 6 5 0,000 7,984E-03 0,08743873 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 7,984E-03 0,08702432 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 7,984E-03 0,08661383 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 7,984E-03 0,08620719 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 7,984E-03 0,08580436 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 7,984E-03 0,08540527 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 7,984E-03 0,08500987 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 7,984E-03 0,08461812 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 7,984E-03 0,08422997 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 7,984E-03 0,08384535 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 7,984E-03 0,08346424 ! cardiac muscle fiber development GO:0048739 7 5 0,000 7,984E-03 0,08308657 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 7,984E-03 0,08271231 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 7,984E-03 0,0823414 ! neutrophil mediated immunity GO:0002446 6 5 0,000 7,984E-03 0,08197381 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 7,984E-03 0,08160948 ! ovulation GO:0030728 6 5 0,000 7,984E-03 0,08124837 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 7,984E-03 0,08089045 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 7,984E-03 0,08053567 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 7,984E-03 0,08018398 ! response to pH GO:0009268 9 5 0,000 7,984E-03 0,07983536 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 7,984E-03 0,07948975 ! proline biosynthetic process GO:0006561 6 5 0,000 7,984E-03 0,07914712 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 7,984E-03 0,07880744 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 7,984E-03 0,07847065 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 7,984E-03 0,07813673 ! polyol catabolic process GO:0046174 7 5 0,000 7,984E-03 0,07780565 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 7,984E-03 0,07747735 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 7,984E-03 0,07715182 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 7,984E-03 0,07682901 ! sister chromatid cohesion GO:0007062 9 5 0,000 7,984E-03 0,07650888 ! nerve growth factor processing GO:0032455 7 5 0,000 7,984E-03 0,07619142 ! urea metabolic process GO:0019627 6 5 0,000 7,984E-03 0,07587658 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 7,984E-03 0,07556433 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 7,984E-03 0,07525464 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 7,984E-03 0,07494748 ! neutrophil activation GO:0042119 5 5 0,000 7,984E-03 0,07464281 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 7,984E-03 0,07434062 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 7,984E-03 0,07404086 ! response to food GO:0032094 5 5 0,000 7,984E-03 0,0737435 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 7,984E-03 0,07344853 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 7,984E-03 0,07315591 ! paraxial mesoderm development GO:0048339 9 5 0,000 7,984E-03 0,0728656 ! forebrain neuron development GO:0021884 7 5 0,000 7,984E-03 0,0725776 ! melanosome organization GO:0032438 7 5 0,000 7,984E-03 0,07229186 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 7,984E-03 0,07200836 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 7,984E-03 0,07172708 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 7,984E-03 0,07144799 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 7,984E-03 0,07117106 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 7,984E-03 0,07089626 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 7,984E-03 0,07062359 ! nucleoside transport GO:0015858 6 5 0,000 7,984E-03 0,070353 ! nucleoside salvage GO:0043174 7 5 0,000 7,984E-03 0,07008447 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 7,984E-03 0,06981799 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 7,984E-03 0,06955353 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 7,984E-03 0,06929107 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 7,984E-03 0,06903057 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 7,984E-03 0,06877203 ! early endosome to late endosome transport GO:0045022 11 5 0,000 7,984E-03 0,06851542 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 7,984E-03 0,06826072 ! depyrimidination GO:0045008 8 5 0,000 7,984E-03 0,0680079 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 7,984E-03 0,06775695 ! 5S class rRNA transcription GO:0042791 8 5 0,000 7,984E-03 0,06750784 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 7,984E-03 0,06726056 ! neuronal ion channel clustering GO:0045161 7 5 0,000 7,984E-03 0,06701508 ! sodium ion homeostasis GO:0055078 6 5 0,000 7,984E-03 0,06677139 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 7,984E-03 0,06652947 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 7,984E-03 0,06628929 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 7,984E-03 0,06605084 ! monocyte differentiation GO:0030224 8 5 0,000 7,984E-03 0,06581409 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 7,984E-03 0,06557904 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 7,984E-03 0,06534567 ! centrosome duplication GO:0051298 5 5 0,000 7,984E-03 0,06511394 ! response to UV-C GO:0010225 6 5 0,000 7,984E-03 0,06488386 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 7,984E-03 0,0646554 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 7,984E-03 0,06442853 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 7,984E-03 0,06420326 ! regulation of dendrite development GO:0050773 12 5 0,000 7,984E-03 0,06397956 ! peptidyl-arginine modification GO:0018195 7 5 0,000 7,984E-03 0,0637574 ! positive regulation of organ growth GO:0046622 6 5 0,000 7,984E-03 0,06353679 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 7,984E-03 0,0633177 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 7,984E-03 0,06310011 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 7,984E-03 0,06288402 ! regulation of dopamine secretion GO:0014059 12 5 0,000 7,984E-03 0,06266939 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 7,984E-03 0,06245623 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 7,984E-03 0,06224452 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 7,984E-03 0,06203423 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 7,984E-03 0,06182536 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 7,984E-03 0,06161789 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 7,984E-03 0,06141181 GO:0032754|positive regulation of interleukin-5 production, ! neural tube patterning GO:0021532 6 5 0,000 7,984E-03 0,06120711 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 7,984E-03 0,06100376 ! histone demethylation GO:0016577 9 5 0,000 7,984E-03 0,06080176 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 7,984E-03 0,0606011 ! regulation of sterol transport GO:0032371 7 5 0,000 7,984E-03 0,06040175 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 7,984E-03 0,06020371 ! enteric nervous system development GO:0048484 8 5 0,000 7,984E-03 0,06000697 ! establishment of planar polarity GO:0001736 6 5 0,000 7,984E-03 0,05981151 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 7,984E-03 0,05961731 ! muscle cell proliferation GO:0033002 8 5 0,000 7,984E-03 0,05942438 ! transcription termination GO:0006353 8 5 0,000 7,984E-03 0,05923269 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 7,984E-03 0,05904223 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 7,984E-03 0,05885299 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 7,984E-03 0,05866496 ! regulation of respiratory burst GO:0060263 8 5 0,000 7,984E-03 0,05847813 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 7,984E-03 0,05829248 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 7,984E-03 0,05810801 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 7,984E-03 0,05792471 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 7,984E-03 0,05774255 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 7,984E-03 0,05756154 ! apical protein localization GO:0045176 6 5 0,000 7,984E-03 0,05738166 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 7,984E-03 0,0572029 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 7,984E-03 0,05702526 ! galactolipid metabolic process GO:0019374 7 5 0,000 7,984E-03 0,05684871 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 7,984E-03 0,05667325 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 7,984E-03 0,05649887 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 7,984E-03 0,05632556 ! triglyceride catabolic process GO:0019433 6 5 0,000 7,984E-03 0,05615331 ! glial cell migration GO:0008347 10 5 0,000 7,984E-03 0,05598211 ! determination of adult lifespan GO:0008340 8 5 0,000 7,984E-03 0,05581195 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 7,984E-03 0,05564283 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 7,984E-03 0,05547472 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 7,984E-03 0,05530763 ! somatic stem cell maintenance GO:0035019 13 5 0,000 7,984E-03 0,05514154 ! cerebellar cortex formation GO:0021697 6 5 0,000 7,984E-03 0,05497644 ! neural plate development GO:0001840 6 5 0,000 7,984E-03 0,05481234 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 7,984E-03 0,0546492 ! regulation of sensory perception GO:0051931 6 5 0,000 7,984E-03 0,05448704 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 7,984E-03 0,05432584 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 7,984E-03 0,05416558 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 7,984E-03 0,05400627 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 7,984E-03 0,0538479 ! sensory cilium assembly GO:0035058 6 5 0,000 7,984E-03 0,05369045 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 7,984E-03 0,05353391 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 7,984E-03 0,05337829 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 7,984E-03 0,05322357 ! spindle assembly GO:0051225 5 5 0,000 7,984E-03 0,05306975 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 7,984E-03 0,05291681 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 7,984E-03 0,05276475 ! protein amino acid prenylation GO:0018346 9 5 0,000 7,984E-03 0,05261356 ! organ regeneration GO:0031100 7 5 0,000 7,984E-03 0,05246324 ! NAD biosynthetic process GO:0009435 7 5 0,000 7,984E-03 0,05231377 ! carnitine metabolic process GO:0009437 5 5 0,000 7,984E-03 0,05216515 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 7,984E-03 0,05201737 ! cellular anion homeostasis GO:0030002 6 5 0,000 7,984E-03 0,05187043 GO:0055081|anion homeostasis, ! cell cycle arrest GO:0007050 150 86 1,000 8,321E-03 0,05391164 ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 8,509E-03 0,05497097 ! response to virus GO:0009615 122 91 1,000 9,277E-03 0,05976822 ! tRNA transcription GO:0009304 11 6 0,000 9,573E-03 0,06150156 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 9,573E-03 0,06133024 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 9,573E-03 0,06115988 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 9,573E-03 0,06099046 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 9,573E-03 0,06082198 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 9,573E-03 0,06065443 ! regulation of helicase activity GO:0051095 11 6 0,000 9,573E-03 0,06048779 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 9,573E-03 0,06032207 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 9,573E-03 0,06015726 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 9,573E-03 0,05999334 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 9,573E-03 0,05983032 ! positive regulation of axon extension GO:0045773 8 6 0,000 9,573E-03 0,05966818 ! prostate gland development GO:0030850 9 6 0,000 9,573E-03 0,05950691 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 9,573E-03 0,05934652 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 9,573E-03 0,05918698 ! forebrain neuron differentiation GO:0021879 9 6 0,000 9,573E-03 0,0590283 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 9,573E-03 0,05887047 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 9,573E-03 0,05871349 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 9,573E-03 0,05855733 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 9,573E-03 0,05840201 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 9,573E-03 0,05824751 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 9,573E-03 0,05809382 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 9,573E-03 0,05794094 ! neuron adhesion GO:0007158 9 6 0,000 9,573E-03 0,05778886 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 9,573E-03 0,05763758 ! establishment of tissue polarity GO:0007164 7 6 0,000 9,573E-03 0,05748709 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 9,573E-03 0,05733739 ! signal peptide processing GO:0006465 8 6 0,000 9,573E-03 0,05718846 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 9,573E-03 0,0570403 ! mRNA stabilization GO:0048255 15 6 0,000 9,573E-03 0,05689291 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 9,573E-03 0,05674628 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 9,573E-03 0,0566004 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 9,573E-03 0,05645528 ! opsonization GO:0008228 8 6 0,000 9,573E-03 0,05631089 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 9,573E-03 0,05616724 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 9,573E-03 0,05602432 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 9,573E-03 0,05588213 ! protein amino acid dealkylation GO:0008214 11 6 0,000 9,573E-03 0,05574065 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 9,573E-03 0,05559989 ! photoreceptor cell development GO:0042461 10 6 0,000 9,573E-03 0,05545984 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 9,573E-03 0,0553205 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 9,573E-03 0,05518185 ! mechanosensory behavior GO:0007638 8 6 0,000 9,573E-03 0,05504389 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 9,573E-03 0,05490663 ! negative regulation of endocytosis GO:0045806 8 6 0,000 9,573E-03 0,05477004 ! response to interferon-gamma GO:0034341 12 6 0,000 9,573E-03 0,05463414 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 9,573E-03 0,0544989 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 9,573E-03 0,05436434 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 9,573E-03 0,05423044 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 9,573E-03 0,05409719 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 9,573E-03 0,0539646 ! cGMP-mediated signaling GO:0019934 10 6 0,000 9,573E-03 0,05383266 ! activation of MAPKKK activity GO:0000185 10 6 0,000 9,573E-03 0,05370136 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 9,573E-03 0,0535707 ! thymic T cell selection GO:0045061 12 6 0,000 9,573E-03 0,05344067 ! protein lipoylation GO:0009249 10 6 0,000 9,573E-03 0,05331128 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 9,573E-03 0,05318251 ! pigment granule organization GO:0048753 11 6 0,000 9,573E-03 0,05305435 ! drug transport GO:0015893 6 6 0,000 9,573E-03 0,05292682 ! cysteine metabolic process GO:0006534 7 6 0,000 9,573E-03 0,0527999 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 9,573E-03 0,05267358 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 9,573E-03 0,05254787 ! histidine metabolic process GO:0006547 6 6 0,000 9,573E-03 0,05242276 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 9,573E-03 0,05229824 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 9,573E-03 0,05217431 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 9,573E-03 0,05205096 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 9,573E-03 0,0519282 ! adenohypophysis development GO:0021984 10 6 0,000 9,573E-03 0,05180602 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 9,573E-03 0,05168441 ! hyperosmotic response GO:0006972 8 6 0,000 9,573E-03 0,05156337 ! ER overload response GO:0006983 7 6 0,000 9,573E-03 0,05144289 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 9,573E-03 0,05132298 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 9,573E-03 0,05120362 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 9,573E-03 0,05108482 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 9,573E-03 0,05096657 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 9,573E-03 0,05084886 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 9,573E-03 0,0507317 ! response to dietary excess GO:0002021 7 6 0,000 9,573E-03 0,05061507 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 9,573E-03 0,05049898 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 9,573E-03 0,05038343 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 9,573E-03 0,0502684 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 9,573E-03 0,05015389 ! glycerol ether catabolic process GO:0044269 8 6 0,000 9,573E-03 0,0500399 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 9,573E-03 0,04992643 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 9,573E-03 0,04981348 ! neuron apoptosis GO:0051402 8 6 0,000 9,573E-03 0,04970103 ! organic alcohol transport GO:0015850 9 6 0,000 9,573E-03 0,04958909 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 9,573E-03 0,04947766 ! T cell mediated immunity GO:0002456 12 6 0,000 9,573E-03 0,04936672 ! male sex determination GO:0030238 9 6 0,000 9,573E-03 0,04925628 ! carnitine transport GO:0015879 8 6 0,000 9,573E-03 0,04914633 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 9,573E-03 0,04903688 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 9,573E-03 0,04892791 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 9,573E-03 0,04881942 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 9,573E-03 0,04871141 ! positive regulation of exocytosis GO:0045921 6 6 0,000 9,573E-03 0,04860388 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 9,573E-03 0,04849682 ! parturition GO:0007567 12 6 0,000 9,573E-03 0,04839024 ! negative regulation of translational initiation GO:0045947 7 6 0,000 9,573E-03 0,04828412 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 9,573E-03 0,04817846 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 9,573E-03 0,04807327 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 9,573E-03 0,04796853 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 9,573E-03 0,04786425 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 9,573E-03 0,04776043 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 9,573E-03 0,04765705 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 9,573E-03 0,04755412 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 9,573E-03 0,04745163 ! macrophage differentiation GO:0030225 10 6 0,000 9,573E-03 0,04734959 ! astrocyte development GO:0014002 14 6 0,000 9,573E-03 0,04724798 ! hyaluronan metabolic process GO:0030212 6 6 0,000 9,573E-03 0,0471468 ! purine base biosynthetic process GO:0009113 14 6 0,000 9,573E-03 0,04704606 ! interaction with symbiont GO:0051702 8 6 0,000 9,573E-03 0,04694575 ! anterograde axon cargo transport GO:0008089 8 6 0,000 9,573E-03 0,04684587 ! skeletal muscle contraction GO:0003009 6 6 0,000 9,573E-03 0,04674641 ! eating behavior GO:0042755 6 6 0,000 9,573E-03 0,04664737 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 9,573E-03 0,04654875 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 9,573E-03 0,04645054 ! response to copper ion GO:0046688 9 6 0,000 9,573E-03 0,04635275 ! DNA topological change GO:0006265 8 6 0,000 9,573E-03 0,04625537 ! response to exogenous dsRNA GO:0043330 8 6 0,000 9,573E-03 0,0461584 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 9,573E-03 0,04606184 ! establishment of melanosome localization GO:0032401 9 6 0,000 9,573E-03 0,04596567 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 9,573E-03 0,04586991 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 9,573E-03 0,04577455 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 9,573E-03 0,04567958 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 9,573E-03 0,045585 ! nucleoside catabolic process GO:0009164 6 6 0,000 9,573E-03 0,04549082 ! gas homeostasis GO:0033483 11 6 0,000 9,573E-03 0,04539703 ! hair follicle maturation GO:0048820 7 6 0,000 9,573E-03 0,04530362 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 9,573E-03 0,04521059 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 9,573E-03 0,04511795 ! Schwann cell development GO:0014044 14 6 0,000 9,573E-03 0,04502568 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 9,573E-03 0,04493379 ! dendrite morphogenesis GO:0048813 9 6 0,000 9,573E-03 0,04484228 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 9,573E-03 0,04475113 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 9,573E-03 0,04466036 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 9,573E-03 0,04456995 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 9,573E-03 0,04447991 ! histone ubiquitination GO:0016574 7 6 0,000 9,573E-03 0,04439024 ! regulation of meiosis GO:0040020 10 6 0,000 9,573E-03 0,04430092 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 9,573E-03 0,04421196 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 9,573E-03 0,04412336 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 9,573E-03 0,04403511 ! regulation of mast cell activation GO:0033003 6 6 0,000 9,573E-03 0,04394722 ! membrane to membrane docking GO:0022614 12 6 0,000 9,573E-03 0,04385968 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 9,573E-03 0,04377248 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 9,573E-03 0,04368563 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 9,573E-03 0,04359912 ! receptor internalization GO:0031623 9 6 0,000 9,573E-03 0,04351296 ! neutrophil homeostasis GO:0001780 6 6 0,000 9,573E-03 0,04342713 ! coenzyme A metabolic process GO:0015936 9 6 0,000 9,573E-03 0,04334165 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 9,573E-03 0,0432565 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 9,573E-03 0,04317168 ! protein deubiquitination GO:0016579 8 6 0,000 9,573E-03 0,0430872 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 9,573E-03 0,04300304 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 9,573E-03 0,04291921 ! peptidyl-histidine modification GO:0018202 9 6 0,000 9,573E-03 0,04283571 ! axonal fasciculation GO:0007413 9 6 0,000 9,573E-03 0,04275254 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 9,573E-03 0,04266968 ! thiamin metabolic process GO:0006772 6 6 0,000 9,573E-03 0,04258715 ! midbrain development GO:0030901 6 6 0,000 9,573E-03 0,04250494 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 9,573E-03 0,04242304 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 9,573E-03 0,04234146 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 9,573E-03 0,04226019 ! progesterone metabolic process GO:0042448 8 6 0,000 9,573E-03 0,04217923 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 9,573E-03 0,04209858 ! glycolipid catabolic process GO:0019377 13 6 0,000 9,573E-03 0,04201824 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 9,573E-03 0,0419382 ! positive regulation of glucose import GO:0046326 6 6 0,000 9,573E-03 0,04185847 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 9,573E-03 0,04177905 ! adult feeding behavior GO:0008343 6 6 0,000 9,573E-03 0,04169992 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 9,573E-03 0,04162109 ! blastocyst growth GO:0001832 15 6 0,000 9,573E-03 0,04154256 ! pigment granule transport GO:0051904 12 6 0,000 9,573E-03 0,04146433 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 9,573E-03 0,04138639 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 9,573E-03 0,04130874 ! catecholamine transport GO:0051937 7 6 0,000 9,573E-03 0,04123138 ! organ or tissue specific immune response GO:0002251 7 6 0,000 9,573E-03 0,04115431 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 9,573E-03 0,04107753 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 9,573E-03 0,04100104 ! negative regulation of B cell activation GO:0050869 9 6 0,000 9,573E-03 0,04092483 ! protein prenylation GO:0018342 10 6 0,000 9,573E-03 0,0408489 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 9,573E-03 0,04077325 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 9,573E-03 0,04069789 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 9,573E-03 0,0406228 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 9,573E-03 0,04054799 ! positive regulation of coagulation GO:0050820 11 6 0,000 9,573E-03 0,04047345 ! electron transport chain GO:0022900 123 94 1,000 9,873E-03 0,04166641 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,01027978 0,04330309 ! protein import GO:0017038 156 99 1,000 0,01090355 0,04584672 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,01090355 0,04576306 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,01111512 0,04656609 ! protein localization in organelle GO:0033365 161 100 1,000 0,01111512 0,04648143 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01115971 0,04658318 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01115971 0,04649879 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01115971 0,04641471 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01115971 0,04633093 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01115971 0,04624745 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01115971 0,04616427 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01115971 0,04608139 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01115971 0,04599881 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01115971 0,04591652 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01115971 0,04583453 ! reproductive behavior GO:0019098 12 7 0,000 0,01115971 0,04575282 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01115971 0,04567141 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01115971 0,04559029 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01115971 0,04550946 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01115971 0,04542891 ! oligopeptide transport GO:0006857 11 7 0,000 0,01115971 0,04534865 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01115971 0,04526867 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01115971 0,04518897 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,01115971 0,04510955 ! RNA methylation GO:0001510 11 7 0,000 0,01115971 0,04503041 ! pericardium development GO:0060039 8 7 0,000 0,01115971 0,04495155 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01115971 0,04487296 ! fibril organization GO:0043206 13 7 0,000 0,01115971 0,04479465 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01115971 0,04471661 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01115971 0,04463884 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01115971 0,04456134 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01115971 0,04448412 ! lipoprotein transport GO:0042953 9 7 0,000 0,01115971 0,04440715 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01115971 0,04433046 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01115971 0,04425403 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01115971 0,04417786 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01115971 0,04410195 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01115971 0,0440263 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01115971 0,04395092 ! chemosensory behavior GO:0007635 9 7 0,000 0,01115971 0,04387579 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01115971 0,04380091 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01115971 0,04372629 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01115971 0,04365193 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01115971 0,04357782 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01115971 0,04350396 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01115971 0,04343035 ! reflex GO:0060004 12 7 0,000 0,01115971 0,04335698 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01115971 0,04328387 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01115971 0,043211 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01115971 0,04313838 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01115971 0,043066 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01115971 0,04299386 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01115971 0,04292196 ! spinal cord patterning GO:0021511 7 7 0,000 0,01115971 0,04285031 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01115971 0,04277889 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01115971 0,04270771 ! adrenal gland development GO:0030325 17 7 0,000 0,01115971 0,04263677 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01115971 0,04256606 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01115971 0,04249559 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01115971 0,04242535 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01115971 0,04235534 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01115971 0,04228556 ! endosome organization GO:0007032 10 7 0,000 0,01115971 0,04221601 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01115971 0,04214669 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01115971 0,0420776 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01115971 0,04200873 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01115971 0,04194009 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01115971 0,04187167 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01115971 0,04180348 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01115971 0,0417355 ! galactose metabolic process GO:0006012 10 7 0,000 0,01115971 0,04166775 ! vesicle fusion GO:0006906 15 7 0,000 0,01115971 0,04160022 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01115971 0,0415329 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01115971 0,04146581 ! organ growth GO:0035265 11 7 0,000 0,01115971 0,04139893 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01115971 0,04133226 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01115971 0,04126581 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01115971 0,04119957 ! retinol metabolic process GO:0042572 9 7 0,000 0,01115971 0,04113355 ! behavioral fear response GO:0001662 13 7 0,000 0,01115971 0,04106774 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01115971 0,04100213 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01115971 0,04093674 ! rRNA modification GO:0000154 12 7 0,000 0,01115971 0,04087155 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01115971 0,04080657 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01115971 0,0407418 ! response to UV-B GO:0010224 11 7 0,000 0,01115971 0,04067723 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01115971 0,04061287 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01115971 0,04054871 ! intermediate filament organization GO:0045109 11 7 0,000 0,01115971 0,04048475 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01115971 0,040421 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01115971 0,04035744 ! fibrinolysis GO:0042730 9 7 0,000 0,01115971 0,04029409 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01115971 0,04023093 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01115971 0,04016797 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01115971 0,04010521 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01115971 0,04004264 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01115971 0,03998027 ! response to tropane GO:0014073 13 7 0,000 0,01115971 0,03991809 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01115971 0,03985611 ! melanosome localization GO:0032400 10 7 0,000 0,01115971 0,03979432 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01115971 0,03973272 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01115971 0,03967131 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01115971 0,03961008 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01115971 0,03954905 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01115971 0,03948821 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01115971 0,03942755 ! mast cell activation GO:0045576 9 7 0,000 0,01115971 0,03936708 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01115971 0,03930679 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01115971 0,03924669 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01115971 0,03918677 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01115971 0,03912703 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01115971 0,03906748 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01115971 0,03900811 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01115971 0,03894891 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01115971 0,0388899 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01115971 0,03883107 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01115971 0,03877241 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01115971 0,03871393 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01115971 0,03865562 ! response to tumor cell GO:0002347 12 7 0,000 0,01115971 0,0385975 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01115971 0,03853954 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01115971 0,03848176 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01115971 0,03842415 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,01115971 0,03836672 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01115971 0,03830945 ! diuresis GO:0030146 12 7 0,000 0,01115971 0,03825236 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01115971 0,03819544 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01115971 0,03813868 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01115971 0,0380821 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01115971 0,03802568 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01115971 0,03796943 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01115971 0,03791335 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01115971 0,03785743 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01115971 0,03780167 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01115971 0,03774608 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01115971 0,03769065 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01115971 0,03763539 ! lymph node development GO:0048535 9 7 0,000 0,01115971 0,03758028 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01115971 0,03752534 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01115971 0,03747056 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01115971 0,03741594 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01115971 0,03736148 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01115971 0,03730717 ! ATP catabolic process GO:0006200 10 7 0,000 0,01115971 0,03725303 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01115971 0,03719904 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01115971 0,0371452 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01115971 0,03709152 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01115971 0,037038 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01115971 0,03698463 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01115971 0,03693142 ! muscle adaptation GO:0043500 12 7 0,000 0,01115971 0,03687835 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01115971 0,03682544 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01115971 0,03677269 ! retina homeostasis GO:0001895 9 7 0,000 0,01115971 0,03672008 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01115971 0,03666762 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01115971 0,03661531 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01115971 0,03656315 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01115971 0,03651114 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01115971 0,03645928 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01115971 0,03640757 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01115971 0,036356 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01274412 0,04145894 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01274412 0,04140039 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,01274412 0,04134199 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01274412 0,04128376 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01274412 0,0412257 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01274412 0,0411678 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01274412 0,04111006 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01274412 0,04105248 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01274412 0,04099507 ! phosphate transport GO:0006817 10 8 0,000 0,01274412 0,04093781 ! N-glycan processing GO:0006491 12 8 0,000 0,01274412 0,04088072 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01274412 0,04082378 ! UTP metabolic process GO:0046051 8 8 0,000 0,01274412 0,040767 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01274412 0,04071038 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01274412 0,04065392 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01274412 0,04059761 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01274412 0,04054146 ! succinate metabolic process GO:0006105 14 8 0,000 0,01274412 0,04048546 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01274412 0,04042962 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01274412 0,04037393 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01274412 0,04031839 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01274412 0,04026301 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01274412 0,04020778 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01274412 0,0401527 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01274412 0,04009777 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01274412 0,040043 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01274412 0,03998837 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01274412 0,03993389 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01274412 0,03987955 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01274412 0,03982537 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01274412 0,03977133 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01274412 0,03971744 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01274412 0,0396637 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01274412 0,0396101 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01274412 0,03955664 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01274412 0,03950333 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01274412 0,03945017 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01274412 0,03939714 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01274412 0,03934426 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01274412 0,03929152 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01274412 0,03923892 ! melanin metabolic process GO:0006582 12 8 0,000 0,01274412 0,03918646 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01274412 0,03913414 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01274412 0,03908196 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01274412 0,03902992 ! macrophage activation GO:0042116 12 8 0,000 0,01274412 0,03897802 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01274412 0,03892626 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01274412 0,03887463 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01274412 0,03882314 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01274412 0,03877179 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01274412 0,03872057 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01274412 0,03866949 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01274412 0,03861854 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01274412 0,03856773 ! ruffle organization GO:0031529 11 8 0,000 0,01274412 0,03851705 ! osteoblast development GO:0002076 13 8 0,000 0,01274412 0,0384665 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01274412 0,03841608 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01274412 0,0383658 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01274412 0,03831565 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01274412 0,03826563 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01274412 0,03821574 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01274412 0,03816598 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01274412 0,03811635 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01274412 0,03806685 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01274412 0,03801747 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01274412 0,03796823 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01274412 0,03791911 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01274412 0,03787012 ! segment specification GO:0007379 10 8 0,000 0,01274412 0,03782126 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01274412 0,03777252 ! cellular extravasation GO:0045123 11 8 0,000 0,01274412 0,0377239 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01274412 0,03767541 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01274412 0,03762705 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01274412 0,03757881 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01274412 0,03753069 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01274412 0,0374827 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01274412 0,03743483 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01274412 0,03738708 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01274412 0,03733946 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01274412 0,03729195 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01274412 0,03724457 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01274412 0,0371973 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01274412 0,03715016 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01274412 0,03710313 ! icosanoid secretion GO:0032309 12 8 0,000 0,01274412 0,03705622 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01274412 0,03700944 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01274412 0,03696277 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01274412 0,03691621 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01274412 0,03686978 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01274412 0,03682346 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01274412 0,03677726 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01274412 0,03673117 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01274412 0,0366852 ! sterol catabolic process GO:0016127 9 8 0,000 0,01274412 0,03663934 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01274412 0,0365936 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01274412 0,03654797 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01274412 0,03650246 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01274412 0,03645706 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01274412 0,03641177 ! prophase GO:0051324 11 8 0,000 0,01274412 0,03636659 ! S phase GO:0051320 8 8 0,000 0,01274412 0,03632153 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01274412 0,03627658 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01274412 0,03623173 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01274412 0,036187 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01274412 0,03614238 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01274412 0,03609787 ! hormone catabolic process GO:0042447 13 8 0,000 0,01274412 0,03605347 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01274412 0,03600918 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01274412 0,035965 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01274412 0,03592092 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01274412 0,03587696 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01274412 0,0358331 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01274412 0,03578934 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01274412 0,0357457 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01274412 0,03570216 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01274412 0,03565873 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01274412 0,0356154 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01274412 0,03557218 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01274412 0,03552906 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01274412 0,03548604 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01274412 0,03544314 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01274412 0,03540033 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01274412 0,03535763 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01432608 0,03969877 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01432608 0,039651 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01432608 0,03960334 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01432608 0,0395558 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01432608 0,03950837 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01432608 0,03946105 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01432608 0,03941385 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01432608 0,03936676 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01432608 0,03931979 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01432608 0,03927292 ! GTP metabolic process GO:0046039 9 9 0,000 0,01432608 0,03922617 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01432608 0,03917952 ! social behavior GO:0035176 14 9 0,000 0,01432608 0,03913299 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01432608 0,03908657 ! artery development GO:0060840 19 9 0,000 0,01432608 0,03904026 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01432608 0,03899406 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01432608 0,03894797 ! response to pain GO:0048265 16 9 0,000 0,01432608 0,03890198 ! protein complex disassembly GO:0043241 17 9 0,000 0,01432608 0,03885611 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01432608 0,03881034 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01432608 0,03876468 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01432608 0,03871913 ! lung alveolus development GO:0048286 17 9 0,000 0,01432608 0,03867369 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01432608 0,03862835 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01432608 0,03858311 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01432608 0,03853799 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01432608 0,03849297 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01432608 0,03844805 ! protein targeting to ER GO:0045047 19 9 0,000 0,01432608 0,03840324 ! T cell selection GO:0045058 18 9 0,000 0,01432608 0,03835853 ! endoderm development GO:0007492 12 9 0,000 0,01432608 0,03831393 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01432608 0,03826943 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01432608 0,03822504 ! arginine catabolic process GO:0006527 10 9 0,000 0,01432608 0,03818074 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01432608 0,03813655 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01432608 0,03809246 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01432608 0,03804848 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01432608 0,03800459 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01432608 0,03796081 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01432608 0,03791712 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01432608 0,03787354 ! mannose metabolic process GO:0006013 9 9 0,000 0,01432608 0,03783006 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01432608 0,03778667 ! receptor clustering GO:0043113 15 9 0,000 0,01432608 0,03774339 ! epithelial cell development GO:0002064 10 9 0,000 0,01432608 0,03770021 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01432608 0,03765712 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01432608 0,03761413 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01432608 0,03757124 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01432608 0,03752845 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01432608 0,03748576 ! motor axon guidance GO:0008045 14 9 0,000 0,01432608 0,03744316 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01432608 0,03740066 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01432608 0,03735825 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01432608 0,03731595 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01432608 0,03727373 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01432608 0,03723162 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01432608 0,03718959 ! DNA ligation GO:0006266 14 9 0,000 0,01432608 0,03714767 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01432608 0,03710583 ! response to amine stimulus GO:0014075 13 9 0,000 0,01432608 0,03706409 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01432608 0,03702245 ! erythrocyte development GO:0048821 11 9 0,000 0,01432608 0,0369809 ! renal water homeostasis GO:0003091 14 9 0,000 0,01432608 0,03693944 ! postreplication repair GO:0006301 11 9 0,000 0,01432608 0,03689807 ! mRNA cleavage GO:0006379 13 9 0,000 0,01432608 0,0368568 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01432608 0,03681562 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01432608 0,03677453 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01432608 0,03673353 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01432608 0,03669263 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01432608 0,03665181 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01432608 0,03661109 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01432608 0,03657046 ! acid secretion GO:0046717 14 9 0,000 0,01432608 0,03652991 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01432608 0,03648946 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01432608 0,03644909 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01432608 0,03640882 ! purine base metabolic process GO:0006144 18 9 0,000 0,01432608 0,03636863 ! oocyte differentiation GO:0009994 12 9 0,000 0,01432608 0,03632853 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01432608 0,03628852 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01432608 0,0362486 ! spleen development GO:0048536 15 9 0,000 0,01432608 0,03620877 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01432608 0,03616902 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01432608 0,03612936 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01432608 0,03608979 ! detection of calcium ion GO:0005513 13 9 0,000 0,01432608 0,03605031 ! blastocyst formation GO:0001825 12 9 0,000 0,01432608 0,03601091 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01432608 0,03597159 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01432608 0,03593237 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01432608 0,03589322 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01432608 0,03585417 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01432608 0,0358152 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01432608 0,03577631 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01432608 0,03573751 ! prepulse inhibition GO:0060134 14 9 0,000 0,01432608 0,03569879 ! embryonic placenta development GO:0001892 12 9 0,000 0,01432608 0,03566015 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01432608 0,0356216 ! insulin secretion GO:0030073 17 9 0,000 0,01432608 0,03558313 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01432608 0,03554475 ! response to nicotine GO:0035094 16 9 0,000 0,01432608 0,03550644 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01432608 0,03546822 ! nucleus localization GO:0051647 15 9 0,000 0,01432608 0,03543009 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01432608 0,03539203 ! localization within membrane GO:0051668 15 9 0,000 0,01432608 0,03535406 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01590559 0,03920993 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01590559 0,03916795 ! neuron fate specification GO:0048665 11 10 0,000 0,01590559 0,03912606 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01590559 0,03908426 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01590559 0,03904255 ! thyroid gland development GO:0030878 19 10 0,000 0,01590559 0,03900092 ! synapsis GO:0007129 13 10 0,000 0,01590559 0,03895939 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01590559 0,03891794 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01590559 0,03887658 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01590559 0,03883531 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01590559 0,03879413 ! sulfate transport GO:0008272 12 10 0,000 0,01590559 0,03875304 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01590559 0,03871203 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01590559 0,0386711 ! androgen metabolic process GO:0008209 13 10 0,000 0,01590559 0,03863027 ! phospholipid efflux GO:0033700 16 10 0,000 0,01590559 0,03858952 ! hippocampus development GO:0021766 19 10 0,000 0,01590559 0,03854886 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01590559 0,03850828 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01590559 0,03846779 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01590559 0,03842738 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01590559 0,03838706 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01590559 0,03834682 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,01590559 0,03830667 ! pathogenesis GO:0009405 13 10 0,000 0,01590559 0,0382666 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01590559 0,03822661 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01590559 0,03818671 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01590559 0,03814689 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01590559 0,03810715 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,01590559 0,0380675 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01590559 0,03802793 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01590559 0,03798844 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01590559 0,03794903 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01590559 0,0379097 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01590559 0,03787046 ! response to X-ray GO:0010165 16 10 0,000 0,01590559 0,0378313 ! B cell proliferation GO:0042100 14 10 0,000 0,01590559 0,03779222 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01590559 0,03775321 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01590559 0,03771429 ! forebrain cell migration GO:0021885 17 10 0,000 0,01590559 0,03767545 ! lipid digestion GO:0044241 15 10 0,000 0,01590559 0,03763669 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01590559 0,03759801 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01590559 0,03755941 ! UV protection GO:0009650 14 10 0,000 0,01590559 0,03752089 ! entry into host cell GO:0030260 20 10 0,000 0,01590559 0,03748244 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01590559 0,03744408 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01590559 0,03740579 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01590559 0,03736758 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01590559 0,03732945 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01590559 0,0372914 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01590559 0,03725343 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01590559 0,03721553 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01590559 0,03717771 ! regulation of organ growth GO:0046620 11 10 0,000 0,01590559 0,03713996 ! response to dsRNA GO:0043331 18 10 0,000 0,01590559 0,0371023 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01590559 0,03706471 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01590559 0,03702719 ! embryonic axis specification GO:0000578 12 10 0,000 0,01590559 0,03698975 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01590559 0,03695239 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01590559 0,0369151 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01590559 0,03687789 ! cranial nerve development GO:0021545 12 10 0,000 0,01590559 0,03684075 ! fucose catabolic process GO:0019317 16 10 0,000 0,01590559 0,03680369 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01590559 0,0367667 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01590559 0,03672978 ! protein sumoylation GO:0016925 12 10 0,000 0,01590559 0,03669294 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01590559 0,03665618 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01590559 0,03661948 ! zymogen activation GO:0031638 14 10 0,000 0,01590559 0,03658287 ! salivary gland development GO:0007431 22 10 0,000 0,01590559 0,03654632 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01590559 0,03650985 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01590559 0,03647344 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01590559 0,03643712 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01590559 0,03640086 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,01590559 0,03636468 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01590559 0,03632857 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01590559 0,03629253 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01590559 0,03625656 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,01590559 0,03622066 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01590559 0,03618483 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01590559 0,03614908 ! detection of bacterium GO:0016045 10 10 0,000 0,01590559 0,03611339 ! embryonic gut development GO:0048566 11 10 0,000 0,01590559 0,03607778 ! activation of innate immune response GO:0002218 10 10 0,000 0,01590559 0,03604223 GO:0002758|innate immune response-activating signal transduction, ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01590559 0,03600676 ! developmental induction GO:0031128 13 10 0,000 0,01590559 0,03597135 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01590559 0,03593602 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01590559 0,03590075 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01590559 0,03586555 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01590559 0,03583043 ! rRNA transcription GO:0009303 17 11 0,000 0,01748267 0,03934456 ! respiratory burst GO:0045730 14 11 0,000 0,01748267 0,0393061 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01748267 0,03926771 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01748267 0,0392294 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01748267 0,03919117 ! virus-host interaction GO:0019048 17 11 0,000 0,01748267 0,03915301 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,01748267 0,03911492 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,01748267 0,03907691 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,01748267 0,03903897 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,01748267 0,0390011 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01748267 0,03896331 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,01748267 0,03892559 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,01748267 0,03888795 ! mating GO:0007618 14 11 0,000 0,01748267 0,03885037 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01748267 0,03881287 ! T cell proliferation GO:0042098 20 11 0,000 0,01748267 0,03877544 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01748267 0,03873809 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,01748267 0,0387008 ! bone resorption GO:0045453 16 11 0,000 0,01748267 0,03866359 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01748267 0,03862645 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01748267 0,03858938 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01748267 0,03855238 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01748267 0,03851546 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01748267 0,0384786 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01748267 0,03844181 ! syncytium formation GO:0006949 15 11 0,000 0,01748267 0,0384051 ! plasma membrane organization GO:0007009 18 11 0,000 0,01748267 0,03836845 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01748267 0,03833187 ! focal adhesion formation GO:0048041 24 11 0,000 0,01748267 0,03829537 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,01748267 0,03825893 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01748267 0,03822256 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01748267 0,03818626 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01748267 0,03815003 ! adult heart development GO:0007512 11 11 0,000 0,01748267 0,03811387 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01748267 0,03807778 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01748267 0,03804176 ! temperature homeostasis GO:0001659 16 11 0,000 0,01748267 0,0380058 ! L-glutamate transport GO:0015813 16 11 0,000 0,01748267 0,03796991 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,01748267 0,03793409 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01748267 0,03789834 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01748267 0,03786265 ! stem cell development GO:0048864 29 11 0,000 0,01748267 0,03782703 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01748267 0,03779148 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01748267 0,037756 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,01748267 0,03772058 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01748267 0,03768523 ! vasoconstriction GO:0042310 15 11 0,000 0,01748267 0,03764994 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01748267 0,03761472 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01748267 0,03757957 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01748267 0,03754448 ! ribosome assembly GO:0042255 13 11 0,000 0,01748267 0,03750946 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01748267 0,0374745 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,01748267 0,03743961 ! chromatin silencing GO:0006342 19 11 0,000 0,01748267 0,03740478 ! nucleosome positioning GO:0016584 13 11 0,000 0,01748267 0,03737002 ! T cell homeostasis GO:0043029 20 11 0,000 0,01748267 0,03733532 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01748267 0,03730068 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,01748267 0,03726611 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01748267 0,03723161 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01748267 0,03719717 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01748267 0,03716279 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01748267 0,03712847 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01748267 0,03709422 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01748267 0,03706003 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,01748267 0,03702591 ! male genitalia development GO:0030539 13 11 0,000 0,01748267 0,03699185 ! cholesterol efflux GO:0033344 19 11 0,000 0,01748267 0,03695785 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,01748267 0,03692391 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,01748267 0,03689003 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01748267 0,03685622 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01748267 0,03682247 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01748267 0,03678878 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01748267 0,03675515 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01748267 0,03672159 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01748267 0,03668808 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01748267 0,03665464 ! lysogeny GO:0030069 18 11 0,000 0,01748267 0,03662125 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,01748267 0,03658793 ! acrosome reaction GO:0007340 13 11 0,000 0,01748267 0,03655467 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01748267 0,03652147 ! lactation GO:0007595 20 12 0,000 0,01905731 0,03977477 ! reproductive cellular process GO:0048610 14 12 0,000 0,01905731 0,03973871 ! tRNA modification GO:0006400 14 12 0,000 0,01905731 0,03970272 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,01905731 0,03966679 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,01905731 0,03963092 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,01905731 0,03959512 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,01905731 0,03955939 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,01905731 0,03952372 ! non-recombinational repair GO:0000726 19 12 0,000 0,01905731 0,03948811 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,01905731 0,03945257 ! peroxisomal transport GO:0043574 21 12 0,000 0,01905731 0,03941709 ! cartilage condensation GO:0001502 18 12 0,000 0,01905731 0,03938167 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,01905731 0,03934632 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,01905731 0,03931103 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01905731 0,03927581 ! heart looping GO:0001947 15 12 0,000 0,01905731 0,03924065 ! palate development GO:0060021 15 12 0,000 0,01905731 0,03920555 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,01905731 0,03917051 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,01905731 0,03913554 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01905731 0,03910063 ! arginine metabolic process GO:0006525 13 12 0,000 0,01905731 0,03906578 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,01905731 0,03903099 ! methionine metabolic process GO:0006555 13 12 0,000 0,01905731 0,03899626 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,01905731 0,0389616 ! Golgi organization GO:0007030 18 12 0,000 0,01905731 0,038927 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,01905731 0,03889246 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,01905731 0,03885798 ! monoamine transport GO:0015844 13 12 0,000 0,01905731 0,03882356 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01905731 0,03878921 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,01905731 0,03875491 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,01905731 0,03872067 ! L-amino acid transport GO:0015807 20 12 0,000 0,01905731 0,0386865 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,01905731 0,03865238 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01905731 0,03861833 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,01905731 0,03858433 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01905731 0,0385504 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,01905731 0,03851652 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,01905731 0,03848271 ! cerebellum development GO:0021549 13 12 0,000 0,01905731 0,03844895 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01905731 0,03841525 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01905731 0,03838161 ! histone acetylation GO:0016573 23 12 0,000 0,01905731 0,03834803 ! histone methylation GO:0016571 15 12 0,000 0,01905731 0,03831451 ! autonomic nervous system development GO:0048483 23 12 0,000 0,01905731 0,03828105 ! gland morphogenesis GO:0022612 23 12 0,000 0,01905731 0,03824765 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,01905731 0,0382143 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,01905731 0,03818101 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,01905731 0,03814778 ! response to gamma radiation GO:0010332 20 12 0,000 0,01905731 0,03811461 ! regulation of epidermis development GO:0045682 17 12 0,000 0,01905731 0,0380815 ! intestinal absorption GO:0050892 19 12 0,000 0,01905731 0,03804844 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,01905731 0,03801544 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01905731 0,0379825 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,01905731 0,03794961 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,01905731 0,03791678 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,01905731 0,03788401 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01905731 0,0378513 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,01905731 0,03781864 ! microspike assembly GO:0030035 23 12 0,000 0,01905731 0,03778604 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,01905731 0,03775349 ! response to cold GO:0009409 14 12 0,000 0,01905731 0,037721 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,02062951 0,04079782 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,02062951 0,04076277 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02062951 0,04072779 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02062951 0,04069286 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,02062951 0,04065799 ! water transport GO:0006833 17 13 0,000 0,02062951 0,04062318 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02062951 0,04058843 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02062951 0,04055373 ! lipid localization GO:0010876 24 13 0,000 0,02062951 0,0405191 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02062951 0,04048453 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02062951 0,04045002 ! organelle fusion GO:0048284 28 13 0,000 0,02062951 0,04041556 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02062951 0,04038117 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02062951 0,04034683 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,02062951 0,04031255 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02062951 0,04027833 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02062951 0,04024416 ! response to hexose stimulus GO:0009746 19 13 0,000 0,02062951 0,04021006 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,02062951 0,04017601 ! glutamate metabolic process GO:0006536 18 13 0,000 0,02062951 0,04014202 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02062951 0,04010809 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02062951 0,04007421 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02062951 0,0400404 ! NAD metabolic process GO:0019674 21 13 0,000 0,02062951 0,04000664 ! exocrine system development GO:0035272 27 13 0,000 0,02062951 0,03997293 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02062951 0,03993928 ! bone mineralization GO:0030282 15 13 0,000 0,02062951 0,03990569 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02062951 0,03987216 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02062951 0,03983868 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02062951 0,03980526 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02062951 0,03977189 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,02062951 0,03973858 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02062951 0,03970533 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,02062951 0,03967213 ! genitalia development GO:0048806 15 13 0,000 0,02062951 0,03963899 ! regulation of cellular pH GO:0030641 20 13 0,000 0,02062951 0,0396059 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,02062951 0,03957287 ! cellular pigmentation GO:0033059 24 13 0,000 0,02062951 0,03953989 ! tissue regeneration GO:0042246 21 13 0,000 0,02062951 0,03950697 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02062951 0,0394741 ! cofactor transport GO:0051181 19 13 0,000 0,02062951 0,03944129 ! NADP metabolic process GO:0006739 18 13 0,000 0,02062951 0,03940853 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02062951 0,03937583 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02062951 0,03934318 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02062951 0,03931058 ! gas transport GO:0015669 18 13 0,000 0,02062951 0,03927804 ! regulation of RNA stability GO:0043487 28 13 0,000 0,02062951 0,03924555 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02062951 0,03921312 ! regulation of axon extension GO:0030516 23 13 0,000 0,02062951 0,03918073 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,02062951 0,03914841 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02062951 0,03911613 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02062951 0,03908391 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02062951 0,03905174 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02062951 0,03901963 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02062951 0,03898757 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,02219928 0,04191983 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,02219928 0,04188544 ! superoxide anion generation GO:0042554 18 14 0,000 0,02219928 0,04185111 ! neuron maturation GO:0042551 21 14 0,000 0,02219928 0,04181683 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,02219928 0,04178261 ! myotube differentiation GO:0014902 21 14 0,000 0,02219928 0,04174845 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,02219928 0,04171434 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,02219928 0,04168028 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,02219928 0,04164629 ! inositol metabolic process GO:0006020 20 14 0,000 0,02219928 0,04161235 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,02219928 0,04157846 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,02219928 0,04154463 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,02219928 0,04151085 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,02219928 0,04147713 ! response to cAMP GO:0051591 19 14 0,000 0,02219928 0,04144347 ! limbic system development GO:0021761 25 14 0,000 0,02219928 0,04140985 ! startle response GO:0001964 21 14 0,000 0,02219928 0,0413763 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,02219928 0,04134279 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,02219928 0,04130934 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,02219928 0,04127595 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,02219928 0,04124261 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,02219928 0,04120932 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,02219928 0,04117609 ! glycine metabolic process GO:0006544 22 14 0,000 0,02219928 0,04114291 ! pituitary gland development GO:0021983 23 14 0,000 0,02219928 0,04110978 ! cellular response to starvation GO:0009267 21 14 0,000 0,02219928 0,04107671 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,02219928 0,04104369 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,02219928 0,04101072 ! regulation of heart rate GO:0002027 23 14 0,000 0,02219928 0,04097781 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,02219928 0,04094495 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,02219928 0,04091214 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,02219928 0,04087938 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,02219928 0,04084668 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,02219928 0,04081403 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,02219928 0,04078143 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,02219928 0,04074888 ! axon cargo transport GO:0008088 27 14 0,000 0,02219928 0,04071639 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,02219928 0,04068394 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,02219928 0,04065155 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,02219928 0,04061921 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,02219928 0,04058692 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02219928 0,04055469 ! mRNA splice site selection GO:0006376 26 14 0,000 0,02219928 0,0405225 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,02219928 0,04049036 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,02219928 0,04045828 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,02219928 0,04042625 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,02219928 0,04039426 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,02219928 0,04036233 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,02219928 0,04033045 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,02219928 0,04029862 ! muscle maintenance GO:0046716 19 14 0,000 0,02219928 0,04026684 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,02219928 0,04023511 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,02219928 0,04020342 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,02219928 0,04017179 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,02219928 0,04014021 ! cell killing GO:0001906 20 14 0,000 0,02219928 0,04010868 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,02219928 0,0400772 ! cilium assembly GO:0042384 20 14 0,000 0,02219928 0,04004576 ! peptide hormone secretion GO:0030072 23 14 0,000 0,02219928 0,04001438 ! metencephalon development GO:0022037 19 15 0,000 0,02376663 0,04280599 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02376663 0,04277249 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,02376663 0,04273905 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,02376663 0,04270566 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,02376663 0,04267232 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,02376663 0,04263904 ! lipid phosphorylation GO:0046834 23 15 0,000 0,02376663 0,0426058 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,02376663 0,04257262 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,02376663 0,04253949 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,02376663 0,04250641 ! bile acid metabolic process GO:0008206 22 15 0,000 0,02376663 0,04247339 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,02376663 0,04244041 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,02376663 0,04240748 ! adult walking behavior GO:0007628 25 15 0,000 0,02376663 0,04237461 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02376663 0,04234179 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,02376663 0,04230901 ! myoblast differentiation GO:0045445 27 15 0,000 0,02376663 0,04227629 ! centrosome cycle GO:0007098 16 15 0,000 0,02376663 0,04224362 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,02376663 0,042211 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,02376663 0,04217843 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,02376663 0,04214591 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,02376663 0,04211344 ! cerebral cortex development GO:0021987 29 15 0,000 0,02376663 0,04208102 ! response to osmotic stress GO:0006970 22 15 0,000 0,02376663 0,04204865 ! vesicle coating GO:0006901 25 15 0,000 0,02376663 0,04201633 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,02376663 0,04198406 ! DNA integration GO:0015074 22 15 0,000 0,02376663 0,04195184 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,02376663 0,04191967 ! peptide secretion GO:0002790 27 15 0,000 0,02376663 0,04188755 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,02376663 0,04185547 ! regulation of vasodilation GO:0042312 24 15 0,000 0,02376663 0,04182345 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,02376663 0,04179147 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,02376663 0,04175955 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,02376663 0,04172767 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,02376663 0,04169584 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,02376663 0,04166406 ! biomineral formation GO:0031214 18 15 0,000 0,02376663 0,04163233 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,02376663 0,04160064 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,02376663 0,04156901 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,02376663 0,04153742 ! dopamine metabolic process GO:0042417 30 15 0,000 0,02376663 0,04150588 ! organic cation transport GO:0015695 19 15 0,000 0,02376663 0,04147439 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,02376663 0,04144295 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,02376663 0,04141155 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,02376663 0,0413802 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,02376663 0,0413489 ! defense response to virus GO:0051607 27 15 0,000 0,02376663 0,04131765 ! peptide hormone processing GO:0016486 19 15 0,000 0,02376663 0,04128644 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,02376663 0,04125528 ! protein secretion GO:0009306 27 16 0,000 0,02533155 0,04393859 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,02533155 0,04390548 ! hormone secretion GO:0046879 25 16 0,000 0,02533155 0,04387242 ! bone remodeling GO:0046849 24 16 0,000 0,02533155 0,04383941 ! endothelial cell migration GO:0043542 22 16 0,000 0,02533155 0,04380645 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,02533155 0,04377353 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,02533155 0,04374067 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02533155 0,04370786 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,02533155 0,04367509 ! glial cell development GO:0021782 24 16 0,000 0,02533155 0,04364238 ! patterning of blood vessels GO:0001569 24 16 0,000 0,02533155 0,04360971 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,02533155 0,04357709 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,02533155 0,04354452 ! protein polyubiquitination GO:0000209 26 16 0,000 0,02533155 0,043512 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,02533155 0,04347953 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,02533155 0,04344711 ! fructose metabolic process GO:0006000 20 16 0,000 0,02533155 0,04341473 ! regulation of protein binding GO:0043393 27 16 0,000 0,02533155 0,04338241 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,02533155 0,04335013 ! negative regulation of immune response GO:0050777 28 16 0,000 0,02533155 0,0433179 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,02533155 0,04328572 ! DNA replication initiation GO:0006270 25 16 0,000 0,02533155 0,04325358 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,02533155 0,04322149 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,02533155 0,04318945 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,02533155 0,04315746 ! diencephalon development GO:0021536 25 16 0,000 0,02533155 0,04312552 ! oogenesis GO:0048477 23 16 0,000 0,02533155 0,04309362 ! neural crest cell migration GO:0001755 24 16 0,000 0,02533155 0,04306177 ! G1 phase GO:0051318 27 16 0,000 0,02533155 0,04302997 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,02533155 0,04299821 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02533155 0,0429665 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,02533155 0,04293484 ! steroid catabolic process GO:0006706 22 16 0,000 0,02533155 0,04290322 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02533155 0,04287165 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,02533155 0,04284013 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,02533155 0,04280865 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,02533155 0,04277722 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,02533155 0,04274584 ! sperm-egg recognition GO:0035036 16 16 0,000 0,02533155 0,0427145 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,02533155 0,0426832 ! nerve development GO:0021675 18 16 0,000 0,02533155 0,04265196 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,02533155 0,04262076 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,02533155 0,0425896 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,02689406 0,04518359 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,02689406 0,04515061 ! negative regulation of defense response GO:0031348 19 17 0,000 0,02689406 0,04511768 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,02689406 0,04508479 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,02689406 0,04505196 ! glycerol metabolic process GO:0006071 20 17 0,000 0,02689406 0,04501917 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,02689406 0,04498643 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,02689406 0,04495373 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02689406 0,04492109 ! signal complex assembly GO:0007172 29 17 0,000 0,02689406 0,04488849 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,02689406 0,04485594 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,02689406 0,04482343 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,02689406 0,04479097 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,02689406 0,04475856 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,02689406 0,0447262 ! memory GO:0007613 25 17 0,000 0,02689406 0,04469388 ! keratinization GO:0031424 17 17 0,000 0,02689406 0,04466161 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,02689406 0,04462939 ! retinoid metabolic process GO:0001523 22 17 0,000 0,02689406 0,04459721 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,02689406 0,04456508 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,02689406 0,044533 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,02689406 0,04450096 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,02689406 0,04446897 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,02689406 0,04443702 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,02689406 0,04440512 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,02689406 0,04437327 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,02689406 0,04434146 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,02689406 0,0443097 ! membrane budding GO:0006900 29 17 0,000 0,02689406 0,04427798 ! heme metabolic process GO:0042168 27 17 0,000 0,02689406 0,04424631 ! actin filament bundle formation GO:0051017 26 17 0,000 0,02689406 0,04421468 ! neuromuscular junction development GO:0007528 23 17 0,000 0,02689406 0,0441831 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,02689406 0,04415156 ! body fluid secretion GO:0007589 27 17 0,000 0,02689406 0,04412007 ! stem cell differentiation GO:0048863 36 17 0,000 0,02689406 0,04408862 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02689406 0,04405722 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,02689406 0,04402586 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,02689406 0,04399455 ! sensory perception of pain GO:0019233 23 17 0,000 0,02689406 0,04396328 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,02689406 0,04393206 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,02689406 0,04390088 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,02689406 0,04386974 ! synaptogenesis GO:0007416 24 17 0,000 0,02689406 0,04383865 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,02689406 0,0438076 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02689406 0,0437766 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,02689406 0,04374564 ! cell-cell junction organization GO:0045216 25 17 0,000 0,02689406 0,04371472 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,02689406 0,04368385 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,02689406 0,04365302 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,02689406 0,04362224 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,02689406 0,0435915 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,02689406 0,0435608 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,02689406 0,04353014 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,02845415 0,04602288 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,02845415 0,04599054 ! positive regulation of translation GO:0045727 28 18 0,000 0,02845415 0,04595825 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,02845415 0,04592599 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,02845415 0,04589379 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02845415 0,04586163 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,02845415 0,04582951 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02845415 0,04579744 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,02845415 0,04576541 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,02845415 0,04573343 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,02845415 0,0457015 ! axis specification GO:0009798 26 18 0,000 0,02845415 0,0456696 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,02845415 0,04563776 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,02845415 0,04560595 ! pancreas development GO:0031016 26 18 0,000 0,02845415 0,04557419 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,02845415 0,04554248 ! glutamine metabolic process GO:0006541 23 18 0,000 0,02845415 0,04551081 ! response to retinoic acid GO:0032526 25 18 0,000 0,02845415 0,04547918 ! pigmentation during development GO:0048066 31 18 0,000 0,02845415 0,0454476 ! central nervous system neuron development GO:0021954 30 18 0,000 0,02845415 0,04541606 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,02845415 0,04538456 ! fucose metabolic process GO:0006004 26 18 0,000 0,02845415 0,04535311 ! response to fungus GO:0009620 19 18 0,000 0,02845415 0,0453217 ! peptide cross-linking GO:0018149 31 18 0,000 0,02845415 0,04529034 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,02845415 0,04525902 ! heart process GO:0003015 27 18 0,000 0,02845415 0,04522774 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,02845415 0,04519651 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,02845415 0,04516532 ! visual learning GO:0008542 35 18 0,000 0,02845415 0,04513417 ! somitogenesis GO:0001756 24 18 0,000 0,02845415 0,04510306 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,02845415 0,045072 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,02845415 0,04504098 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,02845415 0,04501 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,02845415 0,04497907 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,02845415 0,04494817 ! vitamin transport GO:0051180 24 18 0,000 0,02845415 0,04491732 ! hormone transport GO:0009914 27 18 0,000 0,02845415 0,04488652 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,02845415 0,04485575 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,02845415 0,04482503 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02845415 0,04479435 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,02845415 0,04476371 ! cell-cell recognition GO:0009988 20 18 0,000 0,02845415 0,04473311 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,02845415 0,04470256 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,02845415 0,04467204 ! regulation of glucose import GO:0046324 21 18 0,000 0,02845415 0,04464157 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,02845415 0,04461114 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,02845415 0,04458075 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,02845415 0,0445504 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,02845415 0,0445201 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,03001183 0,04692536 ! positive regulation of ossification GO:0045778 30 19 0,000 0,03001183 0,04689348 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,03001183 0,04686164 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,03001183 0,04682985 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,03001183 0,0467981 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,03001183 0,0467664 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,03001183 0,04673473 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,03001183 0,04670311 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,03001183 0,04667154 ! regeneration GO:0031099 32 19 0,000 0,03001183 0,04664 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,03001183 0,04660851 ! response to alkaloid GO:0043279 32 19 0,000 0,03001183 0,04657706 ! sensory perception of taste GO:0050909 23 19 0,000 0,03001183 0,04654565 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,03001183 0,04651429 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,03001183 0,04648296 ! smooth muscle contraction GO:0006939 36 19 0,000 0,03001183 0,04645168 ! peroxisome organization GO:0007031 29 19 0,000 0,03001183 0,04642044 ! digestive system process GO:0022600 30 19 0,000 0,03001183 0,04638925 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,03001183 0,04635809 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,03001183 0,04632698 ! response to vitamin A GO:0033189 26 19 0,000 0,03001183 0,04629591 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,03001183 0,04626488 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,03001183 0,04623389 ! response to starvation GO:0042594 30 19 0,000 0,03001183 0,04620295 ! sex determination GO:0007530 29 19 0,000 0,03001183 0,04617204 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,03001183 0,04614118 ! plasma membrane fusion GO:0045026 23 19 0,000 0,03001183 0,04611035 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,03001183 0,04607957 ! cytolysis GO:0019835 20 19 0,000 0,03001183 0,04604883 ! renal system process GO:0003014 35 19 0,000 0,03001183 0,04601813 ! vasodilation GO:0042311 33 19 0,000 0,03001183 0,04598748 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,03001183 0,04595686 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,03001183 0,04592628 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,03001183 0,04589575 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,03001183 0,04586525 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,03001183 0,04583479 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,03001183 0,04580438 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,03001183 0,04577401 ! sarcomere organization GO:0045214 23 19 0,000 0,03001183 0,04574367 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,03001183 0,04571338 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,03001183 0,04568312 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,03001183 0,04565291 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,03001183 0,04562274 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,03001183 0,0455926 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,03001183 0,04556251 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,03001183 0,04553245 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,03001183 0,04550244 ! protein stabilization GO:0050821 26 19 0,000 0,03001183 0,04547246 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,0315671 0,04779745 ! iron ion transport GO:0006826 37 20 0,000 0,0315671 0,047766 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,0315671 0,0477346 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,0315671 0,04770323 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,0315671 0,04767191 ! response to vitamin GO:0033273 29 20 0,000 0,0315671 0,04764063 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,0315671 0,04760939 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,0315671 0,04757819 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,0315671 0,04754703 ! spinal cord development GO:0021510 31 20 0,000 0,0315671 0,04751592 ! response to ethanol GO:0045471 37 20 0,000 0,0315671 0,04748484 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,0315671 0,0474538 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,0315671 0,04742281 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,0315671 0,04739185 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,0315671 0,04736094 ! chromosome condensation GO:0030261 31 20 0,000 0,0315671 0,04733007 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,0315671 0,04729923 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,0315671 0,04726844 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,0315671 0,04723768 ! pallium development GO:0021543 38 20 0,000 0,0315671 0,04720697 ! DNA modification GO:0006304 28 20 0,000 0,0315671 0,0471763 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,0315671 0,04714566 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,0315671 0,04711507 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,0315671 0,04708451 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,0315671 0,047054 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,0315671 0,04702352 ! collagen catabolic process GO:0030574 25 20 0,000 0,0315671 0,04699309 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,0315671 0,04696269 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,0315671 0,04693233 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,0315671 0,04690202 ! alditol metabolic process GO:0019400 24 20 0,000 0,0315671 0,04687174 ! actin filament-based movement GO:0030048 34 20 0,000 0,0315671 0,0468415 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,03311996 0,04911406 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,03311996 0,04908242 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,03311996 0,04905081 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,03311996 0,04901925 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,03311996 0,04898772 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,03311996 0,04895624 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,03311996 0,0489248 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,03311996 0,04889339 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,03311996 0,04886203 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,03311996 0,04883071 ! protein amino acid acylation GO:0043543 37 21 0,000 0,03311996 0,04879943 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,03311996 0,04876819 ! vesicle docking GO:0048278 27 21 0,000 0,03311996 0,04873699 ! phototransduction GO:0007602 25 21 0,000 0,03311996 0,04870582 ! dendrite development GO:0016358 35 21 0,000 0,03311996 0,0486747 ! visual behavior GO:0007632 39 21 0,000 0,03311996 0,04864362 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,03311996 0,04861258 ! ovarian follicle development GO:0001541 30 21 0,000 0,03311996 0,04858157 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,03311996 0,04855061 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,03311996 0,04851969 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,03311996 0,0484888 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,03311996 0,04845796 ! cell aging GO:0007569 32 21 0,000 0,03311996 0,04842715 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,03311996 0,04839638 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,03311996 0,04836566 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,03311996 0,04833497 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,03311996 0,04830432 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,03311996 0,04827371 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,03311996 0,04824313 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,03311996 0,0482126 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,03311996 0,04818211 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,03311996 0,04815165 ! fatty acid transport GO:0015908 30 21 0,000 0,03311996 0,04812123 ! immunoglobulin production GO:0002377 33 21 0,000 0,03311996 0,04809085 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,03311996 0,04806051 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,03311996 0,04803021 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,03311996 0,04799994 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,03311996 0,04796972 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,03311996 0,04793953 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,03311996 0,04790938 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,03311996 0,04787926 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,03311996 0,04784919 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,03311996 0,04781915 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,03311996 0,04778915 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,03311996 0,04775919 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,03311996 0,04772927 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,03311996 0,04769938 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,03311996 0,04766953 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,03467042 0,0498699 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,03467042 0,04983873 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,03467042 0,0498076 ! viral genome replication GO:0019079 29 22 0,000 0,03467042 0,04977651 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,03467042 0,04974546 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,03467042 0,04971445 ! leukocyte adhesion GO:0007159 38 22 0,000 0,03467042 0,04968347 ! molting cycle process GO:0022404 40 22 0,000 0,03467042 0,04965254 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,03467042 0,04962164 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,03467042 0,04959078 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,03467042 0,04955996 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,03467042 0,04952918 ! vasculogenesis GO:0001570 33 22 0,000 0,03467042 0,04949843 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,03467042 0,04946773 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,03467042 0,04943706 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,03467042 0,04940643 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,03467042 0,04937584 ! lysosome organization GO:0007040 37 22 0,000 0,03467042 0,04934528 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,03467042 0,04931476 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,03467042 0,04928429 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,03467042 0,04925384 ! regulation of behavior GO:0050795 38 22 0,000 0,03467042 0,04922344 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,03467042 0,04919307 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,03467042 0,04916275 ! membrane depolarization GO:0051899 35 22 0,000 0,03467042 0,04913245 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,03467042 0,0491022 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,03467042 0,04907198 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,03467042 0,0490418 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,03467042 0,04901166 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,03467042 0,04898156 ! blastocyst development GO:0001824 37 22 0,000 0,03467042 0,04895149 ! neural tube closure GO:0001843 33 22 0,000 0,03467042 0,04892146 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,03467042 0,04889146 ! protein tetramerization GO:0051262 39 22 0,000 0,03467042 0,0488615 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,03621849 0,05101196 ! neuron fate commitment GO:0048663 32 23 0,000 0,03621849 0,05098074 ! embryonic pattern specification GO:0009880 31 23 0,000 0,03621849 0,05094956 ! myelination GO:0042552 35 23 0,000 0,03621849 0,05091841 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,03621849 0,05088731 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,03621849 0,05085624 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,03621849 0,05082521 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,03621849 0,05079422 ! vesicle targeting GO:0006903 32 23 0,000 0,03621849 0,05076327 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,03621849 0,05073235 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,03621849 0,05070148 ! osteoblast differentiation GO:0001649 40 23 0,000 0,03621849 0,05067064 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,03621849 0,05063983 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,03621849 0,05060907 ! interaction with host GO:0051701 37 23 0,000 0,03621849 0,05057834 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,03621849 0,05054765 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,03621849 0,050517 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,03621849 0,05048638 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,03621849 0,0504558 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,03621849 0,05042526 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,03621849 0,05039475 ! cell fate determination GO:0001709 45 23 0,000 0,03621849 0,05036428 ! pentose metabolic process GO:0019321 31 23 0,000 0,03621849 0,05033385 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,03621849 0,05030346 ! spermatid development GO:0007286 33 23 0,000 0,03621849 0,0502731 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,03621849 0,05024278 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,03621849 0,05021249 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,03621849 0,05018224 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,03621849 0,05015203 ! telomere organization GO:0032200 32 23 0,000 0,03621849 0,05012186 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,03621849 0,05009172 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,03621849 0,05006161 ! regulation of amine transport GO:0051952 38 23 0,000 0,03621849 0,05003155 ! liver development GO:0001889 40 23 0,000 0,03621849 0,05000152 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,03776416 0,05210412 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,03776416 0,05207288 ! initiation of viral infection GO:0019059 42 24 0,000 0,03776416 0,05204168 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,03776416 0,05201052 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,03776416 0,0519794 ! superoxide metabolic process GO:0006801 32 24 0,000 0,03776416 0,05194831 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,03776416 0,05191726 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,03776416 0,05188624 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,03776416 0,05185527 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,03776416 0,05182433 ! sperm motility GO:0030317 27 24 0,000 0,03776416 0,05179342 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,03776416 0,05176256 ! vacuole organization GO:0007033 39 24 0,000 0,03776416 0,05173173 ! receptor metabolic process GO:0043112 37 24 0,000 0,03776416 0,05170093 ! neural crest cell development GO:0014032 39 24 0,000 0,03776416 0,05167018 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,03776416 0,05163946 ! primary neural tube formation GO:0014020 35 24 0,000 0,03776416 0,05160878 ! negative regulation of cell development GO:0010721 56 24 0,000 0,03776416 0,05157813 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,03776416 0,05154752 ! base-excision repair GO:0006284 31 24 0,000 0,03776416 0,05151695 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,03776416 0,05148641 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,03776416 0,05145591 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,03776416 0,05142544 ! glutathione metabolic process GO:0006749 29 24 0,000 0,03776416 0,05139501 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,03776416 0,05136462 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,03776416 0,05133426 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,03776416 0,05130394 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,03930744 0,05336902 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,03930744 0,05333753 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,03930744 0,05330608 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,03930744 0,05327467 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,03930744 0,0532433 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,03930744 0,05321196 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,03930744 0,05318066 ! peptide transport GO:0015833 43 25 0,000 0,03930744 0,05314939 ! male gonad development GO:0008584 33 25 0,000 0,03930744 0,05311817 ! iron ion homeostasis GO:0055072 39 25 0,000 0,03930744 0,05308697 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,03930744 0,05305582 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,03930744 0,0530247 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,03930744 0,05299362 ! phospholipid transport GO:0015914 35 25 0,000 0,03930744 0,05296258 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,03930744 0,05293157 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,03930744 0,0529006 ! detection of light stimulus GO:0009583 30 25 0,000 0,03930744 0,05286966 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,03930744 0,05283876 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,03930744 0,0528079 ! leukocyte proliferation GO:0070661 39 25 0,000 0,03930744 0,05277707 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,03930744 0,05274628 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,04084834 0,05478203 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,04084834 0,0547501 ! translational initiation GO:0006413 43 26 0,000 0,04084834 0,05471821 ! regulation of pH GO:0006885 36 26 0,000 0,04084834 0,05468636 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,04084834 0,05465455 ! circadian rhythm GO:0007623 42 26 0,000 0,04084834 0,05462278 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,04084834 0,05459104 ! post-embryonic development GO:0009791 42 26 0,000 0,04084834 0,05455933 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,04084834 0,05452767 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,04084834 0,05449604 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,04084834 0,05446445 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,04084834 0,05443289 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,04084834 0,05440137 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,04084834 0,05436989 ! regulation of coagulation GO:0050818 39 26 0,000 0,04084834 0,05433845 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,04238685 0,05635246 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,04238685 0,0563199 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,04238685 0,05628738 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,04238685 0,0562549 ! membrane docking GO:0022406 39 27 0,000 0,04238685 0,05622246 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,04238685 0,05619006 ! catechol metabolic process GO:0009712 43 27 0,000 0,04238685 0,05615769 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,04238685 0,05612536 ! acute-phase response GO:0006953 42 27 0,000 0,04238685 0,05609307 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,04238685 0,05606081 ! myofibril assembly GO:0030239 36 27 0,000 0,04238685 0,05602859 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,04238685 0,05599641 ! response to ionizing radiation GO:0010212 47 27 0,000 0,04238685 0,05596426 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,04238685 0,05593216 ! natural killer cell activation GO:0030101 35 27 0,000 0,04238685 0,05590009 ! lipid oxidation GO:0034440 38 27 0,000 0,04238685 0,05586805 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,04238685 0,05583605 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,04238685 0,05580409 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,04238685 0,05577217 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,04238685 0,05574028 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,04238685 0,05570843 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,04238685 0,05567661 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,04392298 0,05766144 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,04392298 0,05762855 ! phenol metabolic process GO:0018958 44 28 0,000 0,04392298 0,0575957 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,04392298 0,05756288 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,04392298 0,0575301 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,04392298 0,05749735 ! cell junction assembly GO:0034329 56 28 0,000 0,04392298 0,05746465 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,04392298 0,05743198 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,04392298 0,05739935 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,04392298 0,05736675 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,04392298 0,05733419 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,04392298 0,05730167 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,04392298 0,05726919 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,04392298 0,05723674 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,04392298 0,05720433 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,04392298 0,05717196 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,04392298 0,05713962 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,04392298 0,05710732 ! mesoderm formation GO:0001707 46 28 0,000 0,04392298 0,05707506 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,04392298 0,05704283 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,04392298 0,05701064 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,04392298 0,05697848 ! ensheathment of neurons GO:0007272 43 28 0,000 0,04392298 0,05694636 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,04392298 0,05691428 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,04392298 0,05688224 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,04392298 0,05685023 ! neural tube formation GO:0001841 41 28 0,000 0,04392298 0,05681825 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,04392298 0,05678631 ! placenta development GO:0001890 37 28 0,000 0,04392298 0,05675441 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,04545673 0,05870325 ! regulation of innate immune response GO:0045088 38 29 0,000 0,04545673 0,05867031 ! ovulation cycle process GO:0022602 41 29 0,000 0,04545673 0,0586374 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,04545673 0,05860453 ! protein targeting to membrane GO:0006612 53 29 0,000 0,04545673 0,0585717 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,04545673 0,05853891 ! mismatch repair GO:0006298 34 29 0,000 0,04545673 0,05850615 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,04545673 0,05847343 ! muscle cell development GO:0055001 38 29 0,000 0,04545673 0,05844074 ! formation of primary germ layer GO:0001704 48 29 0,000 0,04545673 0,05840809 ! telencephalon development GO:0021537 52 29 0,000 0,04545673 0,05837548 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,04545673 0,05834291 ! eye morphogenesis GO:0048592 51 29 0,000 0,04545673 0,05831037 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,04545673 0,05827786 ! tissue homeostasis GO:0001894 42 29 0,000 0,04545673 0,0582454 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,04698812 0,06017409 ! collagen metabolic process GO:0032963 40 30 0,000 0,04698812 0,0601406 ! organic anion transport GO:0015711 51 30 0,000 0,04698812 0,06010716 ! cholesterol transport GO:0030301 46 30 0,000 0,04698812 0,06007374 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,04698812 0,06004037 ! spliceosome assembly GO:0000245 49 30 0,000 0,04698812 0,06000703 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,04698812 0,05997373 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,04698812 0,05994047 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,04698812 0,05990724 ! ceramide metabolic process GO:0006672 43 30 0,000 0,04698812 0,05987405 ! ovulation cycle GO:0042698 43 30 0,000 0,04698812 0,0598409 ! hindbrain development GO:0030902 45 30 0,000 0,04698812 0,05980778 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,04698812 0,0597747 ! adult locomotory behavior GO:0008344 47 30 0,000 0,04698812 0,05974166 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,04698812 0,05970866 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,04698812 0,05967569 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,04698812 0,05964275 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,04698812 0,05960985 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,04851713 0,06151565 ! negative regulation of secretion GO:0051048 49 31 0,000 0,04851713 0,06148176 ! mammary gland development GO:0030879 57 31 0,000 0,04851713 0,0614479 ! glial cell differentiation GO:0010001 55 31 0,000 0,04851713 0,06141409 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,04851713 0,06138031 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,04851713 0,06134656 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,04851713 0,06131285 ! odontogenesis GO:0042476 50 31 0,000 0,04851713 0,06127918 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,04851713 0,06124555 ! segmentation GO:0035282 41 31 0,000 0,04851713 0,06121196 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,04851713 0,0611784 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,04851713 0,06114487 ! metanephros development GO:0001656 58 31 0,000 0,04851713 0,06111139 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,04851713 0,06107794 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,04851713 0,06104453 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,04851713 0,06101115 ! cell fate specification GO:0001708 37 31 0,000 0,04851713 0,06097781 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,04851713 0,06094451 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,04851713 0,06091124 ! regulation of muscle development GO:0048634 48 32 0,000 0,05004378 0,06279361 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,05004378 0,06275937 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,05004378 0,06272517 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,05004378 0,062691 ! meiosis I GO:0007127 52 32 0,000 0,05004378 0,06265688 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,05004378 0,06262279 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,05004378 0,06258874 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,05004378 0,06255472 ! peripheral nervous system development GO:0007422 53 32 0,000 0,05004378 0,06252074 ! regulation of protein stability GO:0031647 48 32 0,000 0,05004378 0,0624868 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,05004378 0,06245289 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,05004378 0,06241903 ! cytokine production GO:0001816 44 32 0,000 0,05004378 0,06238519 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,05004378 0,0623514 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,05004378 0,06231764 ! vesicle localization GO:0051648 47 32 0,000 0,05004378 0,06228392 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,05156806 0,06414632 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,05156806 0,06411164 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,05156806 0,06407701 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,05156806 0,06404241 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,05156806 0,06400785 ! sister chromatid segregation GO:0000819 46 33 0,000 0,05156806 0,06397332 ! ear morphogenesis GO:0042471 42 33 0,000 0,05156806 0,06393884 ! actomyosin structure organization GO:0031032 43 33 0,000 0,05156806 0,06390439 ! cell junction organization GO:0034330 63 33 0,000 0,05156806 0,06386997 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,05156806 0,0638356 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,05156806 0,06380126 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,05156806 0,06376696 GO:0042593|glucose homeostasis, ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,05156806 0,06373269 ! female gonad development GO:0008585 49 33 0,000 0,05156806 0,06369846 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,05156806 0,06366427 ! positive regulation of cell development GO:0010720 54 33 0,000 0,05156806 0,06363012 ! lipid homeostasis GO:0055088 55 33 0,000 0,05156806 0,063596 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,05156806 0,06356192 ! regulation of proteolysis GO:0030162 50 33 0,000 0,05156806 0,06352787 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,05156806 0,06349386 ! cytokinesis GO:0000910 52 33 0,000 0,05156806 0,06345989 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,05156806 0,06342596 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,05308999 0,06526295 ! mRNA catabolic process GO:0006402 48 34 0,000 0,05308999 0,06522808 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,05308999 0,06519326 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,05308999 0,06515847 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,05308999 0,06512372 ! feeding behavior GO:0007631 45 34 0,000 0,05308999 0,065089 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,05308999 0,06505433 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,05308999 0,06501969 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,05308999 0,06498508 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,05308999 0,06495052 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,05308999 0,06491599 ! neuron migration GO:0001764 46 34 0,000 0,05308999 0,06488149 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,05308999 0,06484704 ! female gamete generation GO:0007292 43 34 0,000 0,05308999 0,06481262 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,05308999 0,06477823 ! polyol metabolic process GO:0019751 44 34 0,000 0,05308999 0,06474389 ! aerobic respiration GO:0009060 47 34 0,000 0,05308999 0,06470958 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,05308999 0,0646753 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,05308999 0,06464106 ! embryonic organ development GO:0048568 45 34 0,000 0,05308999 0,06460686 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,05308999 0,0645727 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,05460956 0,06638583 ! Notch signaling pathway GO:0007219 56 35 0,000 0,05460956 0,06635076 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,05460956 0,06631573 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,05460956 0,06628073 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,05460956 0,06624577 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,05460956 0,06621085 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,05460956 0,06617597 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,05460956 0,06614112 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,05460956 0,06610631 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,05460956 0,06607153 ! glycogen metabolic process GO:0005977 48 35 0,000 0,05460956 0,0660368 ! pigment metabolic process GO:0042440 61 35 0,000 0,05460956 0,06600209 ! protein homooligomerization GO:0051260 52 35 0,000 0,05460956 0,06596743 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,05612678 0,06776461 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,05612678 0,06772906 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,05612678 0,06769354 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,05612678 0,06765807 ! negative regulation of binding GO:0051100 58 36 0,000 0,05612678 0,06762262 ! organic ether metabolic process GO:0018904 46 36 0,000 0,05612678 0,06758722 ! tissue remodeling GO:0048771 62 36 0,000 0,05612678 0,06755185 ! neural tube development GO:0021915 50 36 0,000 0,05612678 0,06751652 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,05612678 0,06748123 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,05612678 0,06744597 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,05612678 0,06741075 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,05612678 0,06737557 ! glucan metabolic process GO:0044042 49 36 0,000 0,05612678 0,06734042 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,05764165 0,06912189 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,05764165 0,06908588 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,05764165 0,06904989 ! learning GO:0007612 67 37 0,000 0,05764165 0,06901395 ! ion transmembrane transport GO:0034220 56 37 0,000 0,05764165 0,06897804 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,05764165 0,06894217 ! regulation of protein secretion GO:0050708 51 37 0,000 0,05764165 0,06890634 ! amino acid activation GO:0043038 52 37 0,000 0,05764165 0,06887054 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,05764165 0,06883478 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,05915418 0,07060436 ! gliogenesis GO:0042063 71 38 0,000 0,05915418 0,07056774 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,05915418 0,07053116 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,05915418 0,07049461 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,05915418 0,07045811 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,05915418 0,07042164 ! phagocytosis GO:0006909 60 38 0,000 0,05915418 0,07038521 ! mesenchymal cell development GO:0014031 64 38 0,000 0,05915418 0,07034881 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,05915418 0,07031246 ! maintenance of location in cell GO:0051651 69 38 0,000 0,05915418 0,07027614 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,06066436 0,07203306 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,06066436 0,07199589 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,06066436 0,07195876 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,06066436 0,07192167 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,06066436 0,07188461 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,06066436 0,0718476 ! male sex differentiation GO:0046661 53 39 0,000 0,06066436 0,07181062 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,06066436 0,07177368 ! chromatin remodeling GO:0006338 68 39 0,000 0,06066436 0,07173678 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,06066436 0,07169991 ! JNK cascade GO:0007254 54 39 0,000 0,06066436 0,07166309 ! developmental growth GO:0048589 62 39 0,000 0,06066436 0,0716263 ! cell growth GO:0016049 61 39 0,000 0,06066436 0,07158955 ! synapse organization GO:0050808 55 39 0,000 0,06066436 0,07155284 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,06217221 0,07329374 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,06217221 0,07325619 ! regulation of tube size GO:0035150 60 40 0,000 0,06217221 0,07321868 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,06217221 0,07318121 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,06217221 0,07314378 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,06217221 0,07310638 ! peptide metabolic process GO:0006518 56 40 0,000 0,06217221 0,07306903 ! inner ear development GO:0048839 57 40 0,000 0,06217221 0,07303171 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,06217221 0,07299443 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,06217221 0,07295719 ! double-strand break repair GO:0006302 67 40 0,000 0,06217221 0,07291998 ! B cell differentiation GO:0030183 62 40 0,000 0,06217221 0,07288282 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,06217221 0,07284569 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,06217221 0,0728086 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,06217221 0,07277154 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,06367773 0,07449581 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,06367773 0,07445794 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,06367773 0,07442011 ! glucose transport GO:0015758 52 41 0,000 0,06367773 0,07438231 ! endosome transport GO:0016197 71 41 0,000 0,06367773 0,07434455 ! striated muscle contraction GO:0006941 62 41 0,000 0,06367773 0,07430683 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,06367773 0,07426915 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,06367773 0,07423151 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,06367773 0,0741939 ! biopolymer methylation GO:0043414 62 41 0,000 0,06367773 0,07415634 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,06367773 0,07411881 ! mitochondrial transport GO:0006839 60 42 0,000 0,06518091 0,07583009 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,06518091 0,07579175 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,06518091 0,07575346 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,06518091 0,0757152 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,06518091 0,07567698 ! hexose transport GO:0008645 54 42 0,000 0,06518091 0,07563879 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,06518091 0,07560065 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,06518091 0,07556255 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,06518091 0,07552448 ! excretion GO:0007588 63 42 0,000 0,06518091 0,07548645 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,06518091 0,07544846 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,06518091 0,07541051 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,06518091 0,07537259 ! regulation of cell shape GO:0008360 78 42 0,000 0,06518091 0,07533472 ! positive regulation of binding GO:0051099 59 43 0,000 0,06668177 0,07703067 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,06668177 0,076992 ! leukocyte migration GO:0050900 60 43 0,000 0,06668177 0,07695337 ! neuromuscular process GO:0050905 79 43 0,000 0,06668177 0,07691477 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,06668177 0,07687622 ! tRNA processing GO:0008033 49 43 0,000 0,06668177 0,07683771 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,06668177 0,07679923 ! vesicle organization GO:0016050 79 43 0,000 0,06668177 0,07676079 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,06668177 0,07672239 ! methylation GO:0032259 64 43 0,000 0,06668177 0,07668403 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,0681803 0,07836816 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,0681803 0,07832901 ! glycolysis GO:0006096 53 44 0,000 0,0681803 0,07828991 ! regulation of action potential GO:0001508 71 44 0,000 0,0681803 0,07825084 ! regulation of ion transport GO:0043269 57 44 0,000 0,0681803 0,07821181 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,0681803 0,07817282 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,0681803 0,07813387 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,0681803 0,07809496 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,0681803 0,07805609 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,0681803 0,07801726 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,0681803 0,07797846 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,0681803 0,0779397 ! RNA catabolic process GO:0006401 64 45 0,000 0,06967651 0,07961052 ! positive regulation of defense response GO:0031349 59 45 0,000 0,06967651 0,07957099 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,06967651 0,0795315 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,06967651 0,07949205 ! cell maturation GO:0048469 60 45 0,000 0,06967651 0,07945264 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,06967651 0,07941327 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,07117041 0,08107575 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,07117041 0,08103561 ! cell redox homeostasis GO:0045454 63 46 0,000 0,07117041 0,08099551 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,07117041 0,08095546 ! regulation of ossification GO:0030278 71 46 0,000 0,07117041 0,08091544 ! histone modification GO:0016570 68 46 0,000 0,07117041 0,08087546 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,07117041 0,08083552 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,07266199 0,08248893 ! viral infectious cycle GO:0019058 71 47 0,000 0,07266199 0,08244823 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,07266199 0,08240758 ! endocrine system development GO:0035270 83 47 0,000 0,07266199 0,08236697 ! covalent chromatin modification GO:0016569 75 47 0,000 0,07266199 0,08232639 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,07266199 0,08228586 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,07266199 0,08224536 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,07266199 0,08220491 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,07266199 0,08216449 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,07266199 0,08212411 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,07266199 0,08208378 ! chloride transport GO:0006821 67 48 0,000 0,07415126 0,08372504 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,07415126 0,08368395 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,07415126 0,08364291 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,07415126 0,08360191 ! gastrulation GO:0007369 73 48 0,000 0,07415126 0,08356095 ! heart morphogenesis GO:0003007 65 48 0,000 0,07415126 0,08352003 ! regulation of DNA replication GO:0006275 75 48 0,000 0,07415126 0,08347915 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,07415126 0,08343831 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,07415126 0,08339751 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,07415126 0,08335674 ! regulation of endocytosis GO:0030100 63 48 0,000 0,07415126 0,08331602 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,07415126 0,08327534 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,07415126 0,0832347 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,07563823 0,0848624 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,07563823 0,08482102 ! sensory perception of smell GO:0007608 61 49 0,000 0,07563823 0,08477969 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,07563823 0,08473839 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,07563823 0,08469714 ! RNA elongation GO:0006354 62 49 0,000 0,07563823 0,08465592 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,07563823 0,08461475 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,07563823 0,08457361 ! germ cell development GO:0007281 68 49 0,000 0,07563823 0,08453252 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,07563823 0,08449146 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,07563823 0,08445045 ! cartilage development GO:0051216 70 49 0,000 0,07563823 0,08440947 ! maintenance of location GO:0051235 84 49 0,000 0,07563823 0,08436854 ! regulation of actin filament length GO:0030832 72 50 0,000 0,07712289 0,08598286 ! ear development GO:0043583 72 50 0,000 0,07712289 0,0859412 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,07712289 0,08589959 ! membrane fusion GO:0006944 80 50 0,000 0,07712289 0,08585801 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,07712289 0,08581647 ! lipid modification GO:0030258 73 50 0,000 0,07712289 0,08577497 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,07712289 0,08573352 ! proton transport GO:0015992 75 50 0,000 0,07712289 0,0856921 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,07712289 0,08565072 ! positive regulation of secretion GO:0051047 71 51 0,000 0,07860525 0,08725487 ! hydrogen transport GO:0006818 77 51 0,000 0,07860525 0,08721277 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,07860525 0,08717072 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,07860525 0,08712871 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,07860525 0,08708674 ! adult behavior GO:0030534 80 51 0,000 0,07860525 0,08704482 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,07860525 0,08700293 ! transition metal ion transport GO:0000041 74 52 0,000 0,08008532 0,08859848 ! regulation of cellular component size GO:0032535 74 52 0,000 0,08008532 0,08855588 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,08008532 0,08851333 ! aging GO:0007568 79 52 0,000 0,08008532 0,08847081 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,08008532 0,08842834 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,08008532 0,08838591 ! establishment of organelle localization GO:0051656 85 52 0,000 0,08008532 0,08834352 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,08156309 0,08993055 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,08156309 0,08988745 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,08156309 0,0898444 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,08156309 0,0898014 ! kidney development GO:0001822 90 53 0,000 0,08156309 0,08975843 ! single fertilization GO:0007338 59 53 0,000 0,08156309 0,0897155 ! cell projection assembly GO:0030031 76 53 0,000 0,08156309 0,08967262 ! amino acid transport GO:0006865 84 54 0,000 0,08303858 0,09125119 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,08303858 0,09120761 ! glucose catabolic process GO:0006007 66 54 0,000 0,08303858 0,09116407 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,08303858 0,09112058 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,08303858 0,09107713 ! detection of external stimulus GO:0009581 66 54 0,000 0,08303858 0,09103371 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,08303858 0,09099034 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,08303858 0,09094702 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,08303858 0,09090373 ! exocytosis GO:0006887 74 55 0,000 0,08451178 0,09247245 ! mesoderm development GO:0007498 76 55 0,000 0,08451178 0,09242848 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,08451178 0,09238455 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,08451178 0,09234066 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,0859827 0,09390323 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,0859827 0,09385866 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,0859827 0,09381414 ! carbohydrate transport GO:0008643 74 57 0,000 0,08745133 0,0953713 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,08745133 0,0953261 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,08745133 0,09528094 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,08745133 0,09523583 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,08745133 0,09519076 ! camera-type eye development GO:0043010 88 57 0,000 0,08745133 0,09514573 ! secondary metabolic process GO:0019748 84 57 0,000 0,08745133 0,09510074 ! developmental maturation GO:0021700 75 57 0,000 0,08745133 0,0950558 ! gonad development GO:0008406 79 57 0,000 0,08745133 0,0950109 ! viral reproductive process GO:0022415 87 58 0,000 0,0889177 0,09655841 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,0889177 0,09651284 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,0889177 0,09646731 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,09038179 0,09800948 ! activation of MAPK activity GO:0000187 84 59 0,000 0,09038179 0,09796329 ! lung development GO:0030324 94 59 0,000 0,09038179 0,09791715 ! actin filament organization GO:0007015 95 59 0,000 0,09038179 0,09787105 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,09038179 0,09782499 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,09038179 0,09777898 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,09184361 0,09931373 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,09184361 0,09926706 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,09184361 0,09922043 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,09184361 0,09917385 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,09184361 0,09912731 ! regulation of heart contraction GO:0008016 91 60 0,000 0,09184361 0,09908082 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,09184361 0,09903436 ! fertilization GO:0009566 68 60 0,000 0,09184361 0,09898796 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,09184361 0,09894159 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,09330316 0,10046689 ! meiosis GO:0007126 96 61 0,000 0,09330316 0,10041988 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,09330316 0,10037291 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,09330316 0,10032598 ! urogenital system development GO:0001655 101 61 0,000 0,09330316 0,1002791 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,09330316 0,10023226 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,09330316 0,10018547 ! extracellular matrix organization GO:0030198 103 61 0,000 0,09330316 0,10013872 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,09330316 0,10009201 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,09476046 0,10160795 ! neurotransmitter transport GO:0006836 81 62 0,000 0,09476046 0,1015606 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,09476046 0,1015133 ! respiratory tube development GO:0030323 99 62 0,000 0,09476046 0,10146604 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,09476046 0,10141882 ! meiotic cell cycle GO:0051321 97 62 0,000 0,09476046 0,10137165 ! organelle localization GO:0051640 96 62 0,000 0,09476046 0,10132452 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,09621549 0,10283254 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,09621549 0,10278478 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,09621549 0,10273706 ! viral reproduction GO:0016032 92 63 0,000 0,09621549 0,10268939 ! regulation of lipase activity GO:0060191 109 63 0,000 0,09621549 0,10264176 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,09766827 0,10414327 ! appendage morphogenesis GO:0035107 93 64 0,000 0,09766827 0,10409501 GO:0035108|limb morphogenesis, ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,09766827 0,10404679 ! hexose catabolic process GO:0019320 82 64 0,000 0,09766827 0,10399862 ! respiratory system development GO:0060541 100 64 0,000 0,09766827 0,1039505 ! adaptive immune response GO:0002250 94 64 0,000 0,09766827 0,10390242 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,0991188 0,10539678 ! appendage development GO:0048736 94 65 0,000 0,0991188 0,10534808 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,0991188 0,10529942 ! defense response to bacterium GO:0042742 73 65 0,000 0,0991188 0,1052508 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,0991188 0,10520223 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,0991188 0,10515371 ! activation of immune response GO:0002253 83 65 0,000 0,0991188 0,10510523 ! protein oligomerization GO:0051259 100 65 0,000 0,0991188 0,10505679 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,10056708 0,10654274 ! antigen processing and presentation GO:0019882 96 66 0,000 0,10056708 0,10649368 ! axon guidance GO:0007411 99 66 0,000 0,10056708 0,10644467 ! regulation of immune effector process GO:0002697 101 66 0,000 0,10056708 0,10639571 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,10201311 0,10787593 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,10201311 0,10782636 ! acute inflammatory response GO:0002526 92 68 0,000 0,1034569 0,10930219 ! learning or memory GO:0007611 123 68 0,000 0,1034569 0,10925201 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,1034569 0,10920187 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,1034569 0,10915178 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,1034569 0,10910173 ! rhythmic process GO:0048511 105 68 0,000 0,1034569 0,10905173 ! inorganic anion transport GO:0015698 93 68 0,000 0,1034569 0,10900178 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,10489846 0,11046999 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,10489846 0,11041943 ! response to drug GO:0042493 108 69 0,000 0,10489846 0,11036892 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,10633777 0,11183214 ! humoral immune response GO:0006959 86 70 0,000 0,10633777 0,11178102 ! eye development GO:0001654 111 70 0,000 0,10633777 0,11172996 ! amine transport GO:0015837 101 70 0,000 0,10633777 0,11167894 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,10633777 0,11162797 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,10777486 0,11308494 ! muscle cell differentiation GO:0042692 104 71 0,000 0,10777486 0,11303337 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,10777486 0,11298185 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,10777486 0,11293038 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,10777486 0,11287895 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,10777486 0,11282757 ! response to hypoxia GO:0001666 132 72 0,000 0,10920972 0,11427768 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,10920972 0,11422572 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,10920972 0,1141738 ! negative regulation of transport GO:0051051 116 73 0,000 0,11064235 0,11561899 ! regulation of blood pressure GO:0008217 107 73 0,000 0,11064235 0,11556649 ! tube morphogenesis GO:0035239 118 73 0,000 0,11064235 0,11551403 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,11064235 0,11546162 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,11064235 0,11540925 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,11207276 0,1168483 ! response to oxygen levels GO:0070482 137 74 0,000 0,11207276 0,11679536 ! digestion GO:0007586 97 74 0,000 0,11207276 0,11674246 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,11207276 0,11668961 ! blood coagulation GO:0007596 116 75 0,000 0,11350095 0,11812316 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 0,000 0,11350095 0,11806974 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,11350095 0,11801636 ! amine biosynthetic process GO:0009309 97 76 0,000 0,11492693 0,11944507 ! tRNA metabolic process GO:0006399 95 76 0,000 0,11492693 0,11939112 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,11492693 0,11933722 ! regulation of protein transport GO:0051223 114 76 0,000 0,11492693 0,11928336 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,11635069 0,12070663 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,11635069 0,12065221 ! regulation of DNA binding GO:0051101 119 77 0,000 0,11635069 0,12059783 ! gland development GO:0048732 148 77 0,000 0,11635069 0,12054351 ! sex differentiation GO:0007548 105 77 0,000 0,11635069 0,12048924 ! protein ubiquitination GO:0016567 125 77 0,000 0,11635069 0,12043501 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,11635069 0,12038083 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,11635069 0,12032671 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,11635069 0,12027263 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,11777225 0,12168741 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,11777225 0,12163277 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,1191916 0,12304339 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,1191916 0,12298819 ! T cell activation GO:0042110 134 79 0,000 0,1191916 0,12293304 ! regulation of lyase activity GO:0051339 133 79 0,000 0,1191916 0,12287794 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,1191916 0,12282288 ! chromatin assembly GO:0031497 102 80 0,000 0,12060875 0,12422755 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,12060875 0,12417194 ! forebrain development GO:0030900 131 80 0,000 0,12060875 0,12411639 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,1220237 0,12551633 ! hemostasis GO:0007599 125 81 0,000 0,1220237 0,12546022 ! regulation of neurological system process GO:0031644 122 81 0,000 0,1220237 0,12540416 ! vitamin metabolic process GO:0006766 103 81 0,000 0,1220237 0,12534815 ! ossification GO:0001503 134 82 0,000 0,12343645 0,12674279 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,12343645 0,12668623 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,12484701 0,12807678 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,12484701 0,12801968 ! regulation of defense response GO:0031347 117 84 0,000 0,12625539 0,12940615 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,12625539 0,1293485 ! sterol metabolic process GO:0016125 120 84 0,000 0,12625539 0,12929091 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,12766157 0,13067273 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,12766157 0,1306146 ! rRNA metabolic process GO:0016072 107 85 0,000 0,12766157 0,13055652 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,12766157 0,1304985 ! transcription initiation GO:0006352 118 85 0,000 0,12766157 0,13044053 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,12766157 0,1303826 ! regulation of protein localization GO:0032880 132 85 0,000 0,12766157 0,13032473 ! regulation of membrane potential GO:0042391 128 85 0,000 0,12766157 0,13026691 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,12766157 0,13020914 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,12906558 0,13158282 ! nucleosome organization GO:0034728 114 87 0,000 0,13046741 0,13295305 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,13046741 0,13289417 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,13046741 0,13283534 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,13046741 0,13277656 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,13046741 0,13271784 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,13186706 0,13408233 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,13186706 0,13402308 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,13186706 0,13396388 GO:0016054|organic acid catabolic process, ! protein processing GO:0016485 114 88 0,000 0,13186706 0,13390474 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,13326453 0,13526409 ! reproductive developmental process GO:0003006 127 89 0,000 0,13326453 0,13520442 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,13326453 0,13514481 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,13326453 0,13508525 ! regulation of T cell activation GO:0050863 128 89 0,000 0,13326453 0,13502574 ! leukocyte differentiation GO:0002521 143 90 0,000 0,13465984 0,13637941 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,13465984 0,13631938 ! hormone metabolic process GO:0042445 121 90 0,000 0,13465984 0,13625941 ! ATP metabolic process GO:0046034 137 91 0,000 0,13605298 0,13760856 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,13744396 0,13895434 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,13744396 0,13889328 ! cell fate commitment GO:0045165 141 92 0,000 0,13744396 0,13883229 ! positive regulation of immune response GO:0050778 121 92 0,000 0,13744396 0,13877134 ! DNA recombination GO:0006310 146 92 0,000 0,13744396 0,13871045 ! sulfur metabolic process GO:0006790 118 92 0,000 0,13744396 0,13864961 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,13883278 0,13998921 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,13883278 0,13992787 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,13883278 0,13986658 ! response to oxidative stress GO:0006979 141 94 0,000 0,14021944 0,14120172 ! regulation of binding GO:0051098 151 95 0,000 0,14160395 0,14253352 ! angiogenesis GO:0001525 149 95 0,000 0,14160395 0,14247117 ! carboxylic acid transport GO:0046942 147 95 0,000 0,14160395 0,14240887 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,14298631 0,14373624 ! in utero embryonic development GO:0001701 147 96 0,000 0,14298631 0,14367345 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,14298631 0,14361071 ! protein maturation GO:0051604 129 96 0,000 0,14298631 0,14354802 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,14436653 0,14487042 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,14436653 0,14480724 ! calcium ion transport GO:0006816 167 99 0,000 0,14712053 0,14750532 ! extracellular structure organization GO:0043062 156 99 0,000 0,14712053 0,14744105 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,14849432 0,14875302 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,14849432 0,14868826 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,14849432 0,14862356 ! divalent metal ion transport GO:0070838 171 100 0,000 0,14849432 0,14855891 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,14849432 0,14849432