pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/103-0-real-Parker_GPL887-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL887.an.zip classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle organization GO:0007051 38 27 3,000 1,31E-08 4,78E-05 ! microtubule cytoskeleton organization GO:0000226 113 87 4,000 2,132E-08 3,889E-05 ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 2,000 4,948E-08 6,017E-05 ! Ran GTPase binding GO:0008536 11 9 2,000 7,417E-08 6,764E-05 ! nuclear export GO:0051168 46 42 3,000 8,277E-08 6,039E-05 ! G1/S transition of mitotic cell cycle GO:0000082 54 43 3,000 9,12E-08 5,545E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 55 51 3,000 1,837E-07 9,575E-05 ! mitotic spindle organization GO:0007052 13 12 2,000 1,939E-07 8,841E-05 ! protein export from nucleus GO:0006611 14 14 2,000 3,204E-07 1,299E-04 ! cyclin-dependent protein kinase regulator activity GO:0016538 14 14 2,000 3,204E-07 1,169E-04 ! protein serine/threonine kinase inhibitor activity GO:0030291 17 16 2,000 4,923E-07 1,633E-04 ! protein kinase regulator activity GO:0019887 74 66 3,000 5,248E-07 1,595E-04 ! kinase regulator activity GO:0019207 93 76 3,000 9,282E-07 2,605E-04 ! establishment of RNA localization GO:0051236 97 77 3,000 9,785E-07 2,55E-04 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! RNA localization GO:0006403 99 79 3,000 1,085E-06 2,639E-04 ! interphase of mitotic cell cycle GO:0051329 100 81 3,000 1,2E-06 2,736E-04 ! interphase GO:0051325 103 83 3,000 1,324E-06 2,84E-04 ! androgen receptor binding GO:0050681 34 24 2,000 1,77E-06 3,587E-04 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 112 91 3,000 1,915E-06 3,677E-04 ! RNA export from nucleus GO:0006405 31 27 2,000 2,553E-06 4,657E-04 ! steroid hormone receptor binding GO:0035258 44 34 2,000 5,2E-06 9,033E-04 ! protein kinase inhibitor activity GO:0004860 37 34 2,000 5,2E-06 8,622E-04 ! kinase inhibitor activity GO:0019210 47 35 2,000 5,684E-06 9,015E-04 ! androgen receptor signaling pathway GO:0030521 47 35 2,000 5,684E-06 8,639E-04 ! induction of apoptosis by intracellular signals GO:0008629 56 41 2,000 9,221E-06 1,346E-03 ! positive regulation of cell-matrix adhesion GO:0001954 8 5 1,000 9,742E-06 1,367E-03 GO:0010811|positive regulation of cell-substrate adhesion, ! RNA polymerase II carboxy-terminal domain kinase activity GO:0008353 5 5 1,000 9,742E-06 1,316E-03 ! response to UV GO:0009411 59 45 2,000 1,224E-05 1,595E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 1,46E-05 1,837E-03 ! microtubule nucleation GO:0007020 7 6 1,000 1,46E-05 1,776E-03 ! regulation of focal adhesion formation GO:0051893 6 6 1,000 1,46E-05 1,719E-03 ! negative regulation of protein ubiquitination GO:0031397 7 6 1,000 1,46E-05 1,665E-03 ! GDP-dissociation inhibitor activity GO:0005092 6 6 1,000 1,46E-05 1,614E-03 ! activation of caspase activity by cytochrome c GO:0008635 7 7 1,000 2,043E-05 2,192E-03 ! cerebellar Purkinje cell layer development GO:0021680 7 7 1,000 2,043E-05 2,13E-03 ! steroid hormone receptor signaling pathway GO:0030518 70 55 2,000 2,249E-05 2,279E-03 ! keratinocyte proliferation GO:0043616 9 8 1,000 2,723E-05 2,685E-03 ! regulation of S phase of mitotic cell cycle GO:0007090 8 8 1,000 2,723E-05 2,614E-03 ! positive regulation of Rho GTPase activity GO:0032321 11 8 1,000 2,723E-05 2,547E-03 ! cerebellar cortex formation GO:0021697 9 8 1,000 2,723E-05 2,483E-03 ! regulation of actin filament bundle formation GO:0032231 13 8 1,000 2,723E-05 2,423E-03 GO:0051492|regulation of stress fiber formation, ! adenosine deaminase activity GO:0004000 8 8 1,000 2,723E-05 2,365E-03 ! regulation of caspase activity GO:0043281 78 60 2,000 2,924E-05 2,481E-03 ! Ras GTPase binding GO:0017016 78 61 2,000 3,074E-05 2,548E-03 ! nuclear pore GO:0005643 79 62 2,000 3,228E-05 2,617E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 80 62 2,000 3,228E-05 2,56E-03 ! regulation of endopeptidase activity GO:0052548 81 63 2,000 3,387E-05 2,629E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 9 9 1,000 3,499E-05 2,659E-03 ! cell differentiation in hindbrain GO:0021533 10 9 1,000 3,499E-05 2,605E-03 ! negative regulation of protein kinase activity GO:0006469 78 64 2,000 3,551E-05 2,591E-03 ! response to unfolded protein GO:0006986 66 64 2,000 3,551E-05 2,54E-03 ! nuclear hormone receptor binding GO:0035257 79 64 2,000 3,551E-05 2,491E-03 ! negative regulation of kinase activity GO:0033673 79 65 2,000 3,721E-05 2,561E-03 ! regulation of peptidase activity GO:0052547 86 67 2,000 4,076E-05 2,753E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 12 10 1,000 4,371E-05 2,899E-03 ! positive regulation of Ras GTPase activity GO:0032320 14 10 1,000 4,371E-05 2,847E-03 ! regulation of phosphatase activity GO:0010921 10 10 1,000 4,371E-05 2,797E-03 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 10 10 1,000 4,371E-05 2,749E-03 ! small GTPase binding GO:0031267 86 69 2,000 4,452E-05 2,753E-03 ! negative regulation of transferase activity GO:0051348 85 70 2,000 4,648E-05 2,826E-03 ! hormone receptor binding GO:0051427 85 70 2,000 4,648E-05 2,78E-03 ! response to protein stimulus GO:0051789 73 70 2,000 4,648E-05 2,735E-03 ! pore complex GO:0046930 89 72 2,000 5,058E-05 2,929E-03 ! cerebellar cortex morphogenesis GO:0021696 13 11 1,000 5,339E-05 3,043E-03 ! positive regulation of B cell proliferation GO:0030890 15 11 1,000 5,339E-05 2,996E-03 ! negative regulation of caspase activity GO:0043154 12 11 1,000 5,339E-05 2,951E-03 ! GTPase binding GO:0051020 91 74 2,000 5,49E-05 2,989E-03 ! regulation of cell cycle process GO:0010564 113 75 2,000 5,715E-05 3,066E-03 ! regulation of Ras GTPase activity GO:0032318 88 77 2,000 6,183E-05 3,269E-03 ! regulation of S phase GO:0033261 16 12 1,000 6,403E-05 3,337E-03 ! positive regulation of GTPase activity GO:0043547 17 12 1,000 6,403E-05 3,29E-03 ! midbody GO:0030496 14 12 1,000 6,403E-05 3,244E-03 ! cerebellum morphogenesis GO:0021587 15 13 1,000 7,562E-05 3,779E-03 ! negative regulation of peptidase activity GO:0010466 16 14 1,000 8,817E-05 4,347E-03 ! positive regulation of cell growth GO:0030307 15 14 1,000 8,817E-05 4,289E-03 ! release of cytochrome c from mitochondria GO:0001836 26 14 1,000 8,817E-05 4,232E-03 ! cerebellar cortex development GO:0021695 16 14 1,000 8,817E-05 4,177E-03 ! regulation of B cell proliferation GO:0030888 18 14 1,000 8,817E-05 4,124E-03 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 16 14 1,000 8,817E-05 4,071E-03 ! gene silencing by RNA GO:0031047 17 15 1,000 1,017E-04 4,636E-03 ! regulation of Rho GTPase activity GO:0032319 18 15 1,000 1,017E-04 4,579E-03 ! hindbrain morphogenesis GO:0021575 18 15 1,000 1,017E-04 4,523E-03 ! protein import into nucleus, docking GO:0000059 15 15 1,000 1,017E-04 4,469E-03 ! spindle GO:0005819 126 92 2,000 1,051E-04 4,566E-03 ! regulation of GTPase activity GO:0043087 105 92 2,000 1,051E-04 4,512E-03 ! regulation of cytoskeleton organization GO:0051493 133 93 2,000 1,086E-04 4,606E-03 ! regulation of protein ubiquitination GO:0031396 27 16 1,000 1,161E-04 4,869E-03 ! G2/M transition of mitotic cell cycle GO:0000086 22 16 1,000 1,161E-04 4,814E-03 ! DNA fragmentation involved in apoptosis GO:0006309 18 16 1,000 1,161E-04 4,76E-03 ! skin development GO:0043588 20 17 1,000 1,315E-04 5,331E-03 ! regulation of dephosphorylation GO:0035303 20 17 1,000 1,315E-04 5,273E-03 ! protein phosphatase type 2A complex GO:0000159 21 17 1,000 1,315E-04 5,216E-03 ! neurotransmitter metabolic process GO:0042133 20 17 1,000 1,315E-04 5,159E-03 ! histone binding GO:0042393 26 17 1,000 1,315E-04 5,105E-03 ! response to light stimulus GO:0009416 131 100 2,000 1,347E-04 5,172E-03 ! positive regulation of cell size GO:0045793 19 18 1,000 1,479E-04 5,62E-03 ! spindle microtubule GO:0005876 27 18 1,000 1,479E-04 5,562E-03 ! cerebellum development GO:0021549 20 18 1,000 1,479E-04 5,505E-03 ! negative regulation of translation GO:0017148 31 18 1,000 1,479E-04 5,449E-03 ! cellular response to unfolded protein GO:0034620 21 19 1,000 1,652E-04 6,026E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! positive regulation of fibroblast proliferation GO:0048146 25 19 1,000 1,652E-04 5,966E-03 ! chaperone binding GO:0051087 21 20 1,000 1,834E-04 6,56E-03 ! regulation of cell-matrix adhesion GO:0001952 26 20 1,000 1,834E-04 6,496E-03 GO:0010810|regulation of cell-substrate adhesion, ! cell structure disassembly during apoptosis GO:0006921 31 20 1,000 1,834E-04 6,434E-03 ! apoptotic mitochondrial changes GO:0008637 33 21 1,000 2,026E-04 7,039E-03 ! apoptotic nuclear changes GO:0030262 24 21 1,000 2,026E-04 6,973E-03 ! metencephalon development GO:0022037 25 22 1,000 2,227E-04 7,594E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 33 22 1,000 2,227E-04 7,524E-03 ! positive regulation of B cell activation GO:0050871 26 22 1,000 2,227E-04 7,455E-03 ! DNA catabolic process, endonucleolytic GO:0000737 24 22 1,000 2,227E-04 7,387E-03 ! nuclear chromatin GO:0000790 23 22 1,000 2,227E-04 7,32E-03 ! deaminase activity GO:0019239 24 23 1,000 2,438E-04 7,941E-03 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 25 23 1,000 2,438E-04 7,871E-03 ! actin filament GO:0005884 26 24 1,000 2,658E-04 8,506E-03 ! regulation of ARF GTPase activity GO:0032312 28 24 1,000 2,658E-04 8,432E-03 ! metallocarboxypeptidase activity GO:0004181 24 24 1,000 2,658E-04 8,359E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 35 24 1,000 2,658E-04 8,288E-03 ! ARF GTPase activator activity GO:0008060 29 25 1,000 2,887E-04 8,927E-03 ! positive regulation of cell adhesion GO:0045785 34 26 1,000 3,126E-04 9,583E-03 ! regulation of fibroblast proliferation GO:0048145 32 26 1,000 3,126E-04 9,504E-03 ! response to endoplasmic reticulum stress GO:0034976 30 26 1,000 3,126E-04 9,425E-03 ! fat cell differentiation GO:0045444 30 27 1,000 3,374E-04 0,01008943 ! cyclin-dependent protein kinase activity GO:0004693 28 27 1,000 3,374E-04 0,0100074 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 30 28 1,000 3,632E-04 0,01068382 ! negative regulation of phosphorylation GO:0042326 30 28 1,000 3,632E-04 0,01059835 ! response to heat GO:0009408 33 28 1,000 3,632E-04 0,01051424 ! mitochondrial intermembrane space GO:0005758 41 29 1,000 3,898E-04 0,01119737 ! ER-nuclear signaling pathway GO:0006984 32 29 1,000 3,898E-04 0,01110989 ! condensed nuclear chromosome GO:0000794 31 30 1,000 4,174E-04 0,01180404 ! negative regulation of protein modification process GO:0031400 34 30 1,000 4,174E-04 0,01171324 ! regulation of microtubule-based process GO:0032886 41 30 1,000 4,174E-04 0,01162382 ! negative regulation of phosphorus metabolic process GO:0010563 34 31 1,000 4,459E-04 0,01232387 GO:0045936|negative regulation of phosphate metabolic process, ! response to calcium ion GO:0051592 34 31 1,000 4,459E-04 0,01223121 ! gene silencing GO:0016458 33 31 1,000 4,459E-04 0,01213994 ! double-stranded RNA binding GO:0003725 35 32 1,000 4,754E-04 0,01284557 ! organelle envelope lumen GO:0031970 46 33 1,000 5,057E-04 0,01356556 ! protein serine/threonine phosphatase complex GO:0008287 37 33 1,000 5,057E-04 0,01346654 ! negative regulation of hydrolase activity GO:0051346 36 34 1,000 5,37E-04 0,01419593 ! regulation of B cell activation GO:0050864 40 34 1,000 5,37E-04 0,0140938 ! SMAD binding GO:0046332 39 36 1,000 6,023E-04 0,01569521 ! nucleus organization GO:0006997 42 36 1,000 6,023E-04 0,01558389 ! carboxypeptidase activity GO:0004180 37 36 1,000 6,023E-04 0,01547415 ! cellular response to extracellular stimulus GO:0031668 37 36 1,000 6,023E-04 0,01536594 ! positive regulation of mast cell proliferation GO:0070668 43 36 1,000 6,023E-04 0,01525923 GO:0050671|positive regulation of lymphocyte proliferation, ! hindbrain development GO:0030902 43 37 1,000 6,364E-04 0,01601025 ! metalloexopeptidase activity GO:0008235 39 37 1,000 6,364E-04 0,01590059 ! positive regulation of leukocyte proliferation GO:0070665 47 37 1,000 6,364E-04 0,01579242 GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of translational initiation GO:0006446 50 38 1,000 6,713E-04 0,01654713 ! regulation of ARF protein signal transduction GO:0032012 44 38 1,000 6,713E-04 0,01643608 ! regulation of cell morphogenesis involved in differentiation GO:0010769 45 39 1,000 7,072E-04 0,01719861 ! RNA modification GO:0009451 39 39 1,000 7,072E-04 0,01708471 ! positive regulation of cell development GO:0010720 43 40 1,000 7,439E-04 0,01785479 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 50 40 1,000 7,439E-04 0,01773809 ! lamellipodium GO:0030027 56 41 1,000 7,816E-04 0,01851545 ! protein serine/threonine phosphatase activity GO:0004722 45 42 1,000 8,202E-04 0,01930411 ! positive regulation of cell cycle GO:0045787 56 43 1,000 8,597E-04 0,02010383 ! positive regulation of growth GO:0045927 47 43 1,000 8,597E-04 0,01997578 ! activation of caspase activity GO:0006919 60 43 1,000 8,597E-04 0,01984936 ! nuclear matrix GO:0016363 56 45 1,000 9,414E-04 0,02159875 ! neuromuscular process GO:0050905 56 46 1,000 9,836E-04 0,02242581 ! response to insulin stimulus GO:0032868 57 47 1,000 1,027E-03 0,02326296 ! positive regulation of caspase activity GO:0043280 65 48 1,000 1,071E-03 0,02410997 GO:0010952|positive regulation of peptidase activity, ! protein N-terminus binding GO:0047485 57 48 1,000 1,071E-03 0,02396206 ! regulation of neurotransmitter levels GO:0001505 55 49 1,000 1,116E-03 0,02481438 ! response to temperature stimulus GO:0009266 57 49 1,000 1,116E-03 0,02466399 ! nuclear periphery GO:0034399 60 49 1,000 1,116E-03 0,02451542 ! regulation of mast cell proliferation GO:0070666 57 49 1,000 1,116E-03 0,02436862 ! DNA damage response, signal transduction GO:0042770 84 50 1,000 1,161E-03 0,02521763 ! positive regulation of organelle organization GO:0010638 69 51 1,000 1,208E-03 0,02607584 ! regulation of lymphocyte proliferation GO:0050670 61 52 1,000 1,256E-03 0,02694306 ! cellular component disassembly GO:0022411 69 52 1,000 1,256E-03 0,0267855 ! keratinocyte differentiation GO:0030216 60 53 1,000 1,304E-03 0,02765735 ! regulation of protein catabolic process GO:0042176 56 53 1,000 1,304E-03 0,02749748 ! DNA catabolic process GO:0006308 57 53 1,000 1,304E-03 0,02733945 ! regulation of leukocyte proliferation GO:0070663 65 53 1,000 1,304E-03 0,02718322 GO:0032944|regulation of mononuclear cell proliferation, ! regulation of mitosis GO:0007088 79 55 1,000 1,404E-03 0,02909232 GO:0051783|regulation of nuclear division, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 61 56 1,000 1,455E-03 0,02998124 ! epidermal cell differentiation GO:0009913 66 58 1,000 1,56E-03 0,0319617 ! response to metal ion GO:0010038 65 60 1,000 1,668E-03 0,03399166 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 77 62 1,000 1,78E-03 0,03607 ! positive regulation of protein amino acid phosphorylation GO:0001934 72 62 1,000 1,78E-03 0,03587072 ! focal adhesion GO:0005925 72 62 1,000 1,78E-03 0,03567363 ! negative regulation of cell growth GO:0030308 69 63 1,000 1,837E-03 0,03661979 ! regulation of actin cytoskeleton organization GO:0032956 93 64 1,000 1,895E-03 0,03757292 ! negative regulation of cell size GO:0045792 71 65 1,000 1,954E-03 0,03853287 ! positive regulation of lymphocyte activation GO:0051251 83 65 1,000 1,954E-03 0,03832571 ! response to inorganic substance GO:0010035 71 65 1,000 1,954E-03 0,03812076 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 80 65 1,000 1,954E-03 0,03791799 ! protein import into nucleus GO:0006606 73 66 1,000 2,014E-03 0,03887253 ! cell-substrate adherens junction GO:0005924 76 66 1,000 2,014E-03 0,03866794 ! nuclear import GO:0051170 74 67 1,000 2,075E-03 0,03962509 ! response to peptide hormone stimulus GO:0043434 79 67 1,000 2,075E-03 0,03941871 ! regulation of actin filament-based process GO:0032970 96 67 1,000 2,075E-03 0,03921447 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 83 67 1,000 2,075E-03 0,03901233 ! cell-substrate junction GO:0030055 78 68 1,000 2,136E-03 0,03996424 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 84 68 1,000 2,136E-03 0,03976034 ! mRNA transport GO:0051028 88 69 1,000 2,199E-03 0,04071476 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 79 69 1,000 2,199E-03 0,04050913 ! positive regulation of ligase activity GO:0051351 86 70 1,000 2,262E-03 0,04146596 ! positive regulation of phosphorylation GO:0042327 82 70 1,000 2,262E-03 0,04125863 ! cell cortex GO:0005938 77 70 1,000 2,262E-03 0,04105337 ! nuclear chromosome part GO:0044454 94 70 1,000 2,262E-03 0,04085013 ! protein localization in nucleus GO:0034504 78 71 1,000 2,326E-03 0,04180187 ! positive regulation of phosphorus metabolic process GO:0010562 85 72 1,000 2,391E-03 0,0427596 GO:0045937|positive regulation of phosphate metabolic process, ! protein transporter activity GO:0008565 80 73 1,000 2,457E-03 0,04372321 ! exopeptidase activity GO:0008238 81 73 1,000 2,457E-03 0,04351096 ! positive regulation of leukocyte activation GO:0002696 92 73 1,000 2,457E-03 0,04330077 ! regulation of Rho protein signal transduction GO:0035023 88 73 1,000 2,457E-03 0,04309259 ! positive regulation of cell activation GO:0050867 94 75 1,000 2,591E-03 0,04523062 ! regulation of ubiquitin-protein ligase activity GO:0051438 92 75 1,000 2,591E-03 0,04501524 ! negative regulation of growth GO:0045926 85 76 1,000 2,66E-03 0,04598497 ! cell leading edge GO:0031252 97 76 1,000 2,66E-03 0,04576806 ! condensed chromosome GO:0000793 106 76 1,000 2,66E-03 0,04555319 ! regulation of ligase activity GO:0051340 95 78 1,000 2,799E-03 0,04771671 ! positive regulation of protein modification process GO:0031401 100 78 1,000 2,799E-03 0,04749477 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 88 80 1,000 2,942E-03 0,04968641 ! regulation of catabolic process GO:0009894 87 80 1,000 2,942E-03 0,04945744 ! mitochondrion organization GO:0007005 104 82 1,000 3,088E-03 0,05167638 ! cellular respiration GO:0045333 85 82 1,000 3,088E-03 0,05144042 ! regulation of cell adhesion GO:0030155 98 83 1,000 3,162E-03 0,05243928 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 101 83 1,000 3,162E-03 0,052202 GO:0010498|proteasomal protein catabolic process, ! adherens junction GO:0005912 100 86 1,000 3,39E-03 0,0557141 ! pigment granule GO:0048770 101 87 1,000 3,468E-03 0,05673504 GO:0042470|melanosome, ! regulation of cell morphogenesis GO:0022604 100 87 1,000 3,468E-03 0,05648175 ! protein kinase binding GO:0019901 115 89 1,000 3,626E-03 0,0587901 ! response to virus GO:0009615 109 90 1,000 3,706E-03 0,05982407 ! regulation of cellular component biogenesis GO:0044087 115 92 1,000 3,869E-03 0,06217716 ! cell cycle arrest GO:0007050 103 93 1,000 3,952E-03 0,06322681 ! protein import GO:0017038 102 93 1,000 3,952E-03 0,06295071 ! Ras protein signal transduction GO:0007265 118 93 1,000 3,952E-03 0,06267701 ! anchoring junction GO:0070161 108 94 1,000 4,035E-03 0,06372385 ! protein localization in organelle GO:0033365 104 95 1,000 4,119E-03 0,06477456 ! Wnt receptor signaling pathway GO:0016055 121 95 1,000 4,119E-03 0,06449656 ! electron transport chain GO:0022900 104 97 1,000 4,29E-03 0,06688733 ! microtubule associated complex GO:0005875 135 97 1,000 4,29E-03 0,0666027 ! nuclear chromosome GO:0000228 127 100 1,000 4,553E-03 0,0703807 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016810 105 100 1,000 4,553E-03 0,07008374 ! regulation of lymphocyte activation GO:0051249 123 100 1,000 4,553E-03 0,06978927 ! positive regulation of epidermal growth factor receptor activity GO:0045741 6 5 0,000 5,065E-03 0,07731067 ! negative regulation of S phase of mitotic cell cycle GO:0045749 5 5 0,000 5,065E-03 0,07698854 ! positive regulation of fatty acid biosynthetic process GO:0045723 5 5 0,000 5,065E-03 0,07666908 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 6 5 0,000 5,065E-03 0,07635227 ! response to superoxide GO:0000303 5 5 0,000 5,065E-03 0,07603806 ! negative regulation of small GTPase mediated signal transduction GO:0051058 6 5 0,000 5,065E-03 0,07572643 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 6 5 0,000 5,065E-03 0,07541734 GO:0032479|regulation of type I interferon production, ! regulation of hormone biosynthetic process GO:0046885 5 5 0,000 5,065E-03 0,07511077 ! calcium:cation antiporter activity GO:0015368 5 5 0,000 5,065E-03 0,07480668 ! quinolinate metabolic process GO:0046874 5 5 0,000 5,065E-03 0,07450504 ! biotin binding GO:0009374 7 5 0,000 5,065E-03 0,07420582 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 5,065E-03 0,073909 ! tongue development GO:0043586 6 5 0,000 5,065E-03 0,07361454 ! nose development GO:0043584 5 5 0,000 5,065E-03 0,07332242 ! cell proliferation in forebrain GO:0021846 5 5 0,000 5,065E-03 0,07303261 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 5 5 0,000 5,065E-03 0,07274508 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 5,065E-03 0,0724598 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 5 0,000 5,065E-03 0,07217676 ! drug:hydrogen antiporter activity GO:0015307 6 5 0,000 5,065E-03 0,07189591 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! nuclear mRNA 3'-splice site recognition GO:0000389 6 5 0,000 5,065E-03 0,07161725 ! glycolipid transport GO:0046836 6 5 0,000 5,065E-03 0,07134073 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 6 5 0,000 5,065E-03 0,07106634 ! regulation of respiratory gaseous exchange GO:0043576 6 5 0,000 5,065E-03 0,07079406 ! regulation of protein export from nucleus GO:0046825 5 5 0,000 5,065E-03 0,07052385 ! neuron adhesion GO:0007158 5 5 0,000 5,065E-03 0,0702557 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 5 5 0,000 5,065E-03 0,06998958 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 5 0,000 5,065E-03 0,06972547 ! opioid peptide activity GO:0001515 6 5 0,000 5,065E-03 0,06946334 ! selenocysteine incorporation GO:0001514 5 5 0,000 5,065E-03 0,06920318 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 6 5 0,000 5,065E-03 0,06894496 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 8 5 0,000 5,065E-03 0,06868866 ! cardiac muscle cell proliferation GO:0060038 6 5 0,000 5,065E-03 0,06843426 GO:0014855|striated muscle cell proliferation, ! dsRNA fragmentation GO:0031050 6 5 0,000 5,065E-03 0,06818173 GO:0035196|gene silencing by miRNA, production of miRNAs, GO:0035195|gene silencing by miRNA, ! ruffle membrane GO:0032587 6 5 0,000 5,065E-03 0,06793106 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 5,065E-03 0,06768223 ! negative regulation of receptor-mediated endocytosis GO:0048261 7 5 0,000 5,065E-03 0,06743522 ! clathrin coat assembly GO:0048268 6 5 0,000 5,065E-03 0,06719 ! cerebral cortex cell migration GO:0021795 5 5 0,000 5,065E-03 0,06694656 ! eukaryotic translation elongation factor 1 complex GO:0005853 5 5 0,000 5,065E-03 0,06670487 ! membrane hyperpolarization GO:0060081 5 5 0,000 5,065E-03 0,06646493 ! regulation of striated muscle cell differentiation GO:0051153 6 5 0,000 5,065E-03 0,0662267 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 5,065E-03 0,06599018 ! translation repressor activity GO:0030371 8 5 0,000 5,065E-03 0,06575534 ! positive regulation of muscle cell differentiation GO:0051149 6 5 0,000 5,065E-03 0,06552216 ! smooth muscle cell differentiation GO:0051145 6 5 0,000 5,065E-03 0,06529063 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 5,065E-03 0,06506074 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 5 5 0,000 5,065E-03 0,06483245 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 5,065E-03 0,06460577 GO:0046329|negative regulation of JNK cascade, ! double-stranded telomeric DNA binding GO:0003691 6 5 0,000 5,065E-03 0,06438066 ! negative regulation of heart contraction GO:0045822 5 5 0,000 5,065E-03 0,06415712 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 5,065E-03 0,06393512 ! microfibril GO:0001527 5 5 0,000 5,065E-03 0,06371465 ! troponin I binding GO:0031013 5 5 0,000 5,065E-03 0,0634957 ! negative regulation of viral genome replication GO:0045071 6 5 0,000 5,065E-03 0,06327825 ! traversing start control point of mitotic cell cycle GO:0007089 6 5 0,000 5,065E-03 0,06306228 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 5,065E-03 0,06284779 ! dorsal/ventral neural tube patterning GO:0021904 5 5 0,000 5,065E-03 0,06263474 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 5,065E-03 0,06242314 ! protein lipoylation GO:0009249 14 5 0,000 5,065E-03 0,06221296 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 5,065E-03 0,06200419 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 5,065E-03 0,06179682 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of isotype switching to IgG isotypes GO:0048302 5 5 0,000 5,065E-03 0,06159083 ! transmembrane-ephrin receptor activity GO:0005005 6 5 0,000 5,065E-03 0,06138621 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 5,065E-03 0,06118294 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 5,065E-03 0,06098102 ! glutamate catabolic process GO:0006538 6 5 0,000 5,065E-03 0,06078043 ! microvillus organization GO:0032528 5 5 0,000 5,065E-03 0,06058115 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 6 5 0,000 5,065E-03 0,06038317 ! tyrosine catabolic process GO:0006572 5 5 0,000 5,065E-03 0,06018648 ! response to pH GO:0009268 5 5 0,000 5,065E-03 0,05999107 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 5 0,000 5,065E-03 0,05979692 ! regulation of protein import into nucleus, translocation GO:0033158 5 5 0,000 5,065E-03 0,05960403 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 5,065E-03 0,05941238 ! polyol biosynthetic process GO:0046173 5 5 0,000 5,065E-03 0,05922195 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 7 5 0,000 5,065E-03 0,05903275 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 5,065E-03 0,05884474 ! fibroblast growth factor receptor activity GO:0005007 6 5 0,000 5,065E-03 0,05865793 ! protein-DNA loading ATPase activity GO:0033170 6 5 0,000 5,065E-03 0,05847231 GO:0003689|DNA clamp loader activity, ! mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276 5 5 0,000 5,065E-03 0,05828785 ! anaerobic glycolysis GO:0019642 5 5 0,000 5,065E-03 0,05810456 GO:0004459|L-lactate dehydrogenase activity, ! adenosine receptor activity, G-protein coupled GO:0001609 6 5 0,000 5,065E-03 0,05792241 ! regulation of retinoic acid receptor signaling pathway GO:0048385 6 5 0,000 5,065E-03 0,0577414 ! peroxisomal matrix GO:0005782 5 5 0,000 5,065E-03 0,05756152 GO:0031907|microbody lumen, ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 5,065E-03 0,05738276 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 6 5 0,000 5,065E-03 0,05720511 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 5,065E-03 0,05702855 ! multivesicular body GO:0005771 5 5 0,000 5,065E-03 0,05685307 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 5,065E-03 0,05667868 GO:0032430|positive regulation of phospholipase A2 activity, ! paraxial mesoderm formation GO:0048341 6 5 0,000 5,065E-03 0,05650535 ! insulin-like growth factor I binding GO:0031994 6 5 0,000 5,065E-03 0,05633308 ! mitochondrial outer membrane translocase complex GO:0005742 5 5 0,000 5,065E-03 0,05616185 ! peptidyl-histidine phosphorylation GO:0018106 6 5 0,000 5,065E-03 0,05599166 ! negative regulation of lipoprotein lipase activity GO:0051005 5 5 0,000 5,065E-03 0,05582251 ! epithelial cell maturation GO:0002070 14 5 0,000 5,065E-03 0,05565437 ! positive regulation of lipoprotein lipase activity GO:0051006 6 5 0,000 5,065E-03 0,05548724 ! muscle thin filament assembly GO:0030240 5 5 0,000 5,065E-03 0,05532111 ! regulation of protein amino acid autophosphorylation GO:0031952 5 5 0,000 5,065E-03 0,05515597 ! nitric-oxide synthase regulator activity GO:0030235 6 5 0,000 5,065E-03 0,05499181 ! negative regulation of fatty acid metabolic process GO:0045922 14 5 0,000 5,065E-03 0,05482863 ! regulation of glycoprotein biosynthetic process GO:0010559 6 5 0,000 5,065E-03 0,05466642 ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,065E-03 0,05450516 ! positive regulation of translational initiation GO:0045948 6 5 0,000 5,065E-03 0,05434485 ! nonhomologous end joining complex GO:0070419 6 5 0,000 5,065E-03 0,05418548 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! depyrimidination GO:0045008 5 5 0,000 5,065E-03 0,05402704 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 5,065E-03 0,05386953 ! ATPase activator activity GO:0001671 5 5 0,000 5,065E-03 0,05371293 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 5,065E-03 0,05355724 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! DNA damage response, signal transduction resulting in transcription GO:0042772 17 5 0,000 5,065E-03 0,05340245 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! calcium sensitive guanylate cyclase activator activity GO:0008048 5 5 0,000 5,065E-03 0,05324856 ! regulation of cholesterol biosynthetic process GO:0045540 5 5 0,000 5,065E-03 0,05309554 ! positive regulation of collagen metabolic process GO:0010714 6 5 0,000 5,065E-03 0,05294341 GO:0032967|positive regulation of collagen biosynthetic process, ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 7 5 0,000 5,065E-03 0,05279214 ! regulation of protein amino acid dephosphorylation GO:0035304 7 5 0,000 5,065E-03 0,05264174 ! cardiac myofibril assembly GO:0055003 5 5 0,000 5,065E-03 0,05249219 ! anterograde axon cargo transport GO:0008089 6 5 0,000 5,065E-03 0,05234348 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,065E-03 0,05219562 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 5,065E-03 0,05204859 GO:0003923|GPI-anchor transamidase activity, ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 5,065E-03 0,05190239 ! thiamin and derivative metabolic process GO:0042723 5 5 0,000 5,065E-03 0,051757 ! protein localization to telomere GO:0070198 7 5 0,000 5,065E-03 0,05161243 ! response to exogenous dsRNA GO:0043330 5 5 0,000 5,065E-03 0,05146866 ! MutSalpha complex binding GO:0032407 7 5 0,000 5,065E-03 0,05132569 ! bile acid biosynthetic process GO:0006699 5 5 0,000 5,065E-03 0,05118352 ! negative regulation of fat cell differentiation GO:0045599 6 5 0,000 5,065E-03 0,05104213 ! enucleate erythrocyte differentiation GO:0043353 7 5 0,000 5,065E-03 0,05090151 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 5,065E-03 0,05076167 ! nerve growth factor binding GO:0048406 7 5 0,000 5,065E-03 0,0506226 ! platelet-derived growth factor binding GO:0048407 8 5 0,000 5,065E-03 0,05048429 ! high-density lipoprotein binding GO:0008035 6 5 0,000 5,065E-03 0,05034673 ! negative regulation of focal adhesion formation GO:0051895 5 5 0,000 5,065E-03 0,05020992 ! transcription initiation factor activity GO:0016986 5 5 0,000 5,065E-03 0,05007385 ! gas homeostasis GO:0033483 5 5 0,000 5,065E-03 0,04993851 ! Schwann cell development GO:0014044 5 5 0,000 5,065E-03 0,04980391 ! CD4-positive, alpha beta T cell differentiation GO:0043367 5 5 0,000 5,065E-03 0,04967003 ! cyclohydrolase activity GO:0019238 5 5 0,000 5,065E-03 0,04953686 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 5,065E-03 0,04940441 ! response to pheromone GO:0019236 5 5 0,000 5,065E-03 0,04927266 GO:0016503|pheromone receptor activity, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 5 5 0,000 5,065E-03 0,04914162 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 5,065E-03 0,04901127 ! rhombomere development GO:0021546 6 5 0,000 5,065E-03 0,04888161 ! alanine transport GO:0032328 6 5 0,000 5,065E-03 0,04875264 ! superoxide-generating NADPH oxidase activity GO:0016175 5 5 0,000 5,065E-03 0,04862434 ! NAD(P)H oxidase activity GO:0016174 5 5 0,000 5,065E-03 0,04849672 ! ventral spinal cord interneuron specification GO:0021521 7 5 0,000 5,065E-03 0,04836976 GO:0021514|ventral spinal cord interneuron differentiation, GO:0060579|ventral spinal cord interneuron fate commitment, ! spinal cord motor neuron cell fate specification GO:0021520 6 5 0,000 5,065E-03 0,04824347 ! regulation of meiosis GO:0040020 6 5 0,000 5,065E-03 0,04811784 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 6 5 0,000 5,065E-03 0,04799286 GO:0000085|G2 phase of mitotic cell cycle, ! parasympathetic nervous system development GO:0048486 5 5 0,000 5,065E-03 0,04786852 ! lymphocyte costimulation GO:0031294 5 5 0,000 5,065E-03 0,04774483 GO:0031295|T cell costimulation, ! response to tumor cell GO:0002347 7 5 0,000 5,065E-03 0,04762178 ! RS domain binding GO:0050733 6 5 0,000 5,065E-03 0,04749936 ! telomerase holoenzyme complex GO:0005697 6 5 0,000 5,065E-03 0,04737756 ! negative regulation of lipoprotein metabolic process GO:0050748 6 5 0,000 5,065E-03 0,04725639 ! B cell homeostasis GO:0001782 6 5 0,000 5,065E-03 0,04713584 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 5,065E-03 0,0470159 ! anaphase GO:0051322 7 5 0,000 5,065E-03 0,04689657 GO:0000090|mitotic anaphase, ! S phase GO:0051320 5 5 0,000 5,065E-03 0,04677785 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 5,065E-03 0,04665972 GO:0050820|positive regulation of coagulation, ! ribonuclease H activity GO:0004523 14 5 0,000 5,065E-03 0,04654219 ! AP-2 adaptor complex GO:0030122 5 5 0,000 5,065E-03 0,04642525 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 6 5 0,000 5,065E-03 0,0463089 ! diuresis GO:0030146 5 5 0,000 5,065E-03 0,04619312 GO:0030147|natriuresis, ! phosphatidylcholine binding GO:0031210 5 5 0,000 5,065E-03 0,04607793 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 5,065E-03 0,04596331 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 5,065E-03 0,04584925 ! very-low-density lipoprotein particle clearance GO:0034447 6 5 0,000 5,065E-03 0,04573577 ! GTP-Rho binding GO:0017049 5 5 0,000 5,065E-03 0,04562284 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 5,065E-03 0,04551047 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 5,065E-03 0,04539865 ! chondroitin sulfotransferase activity GO:0034481 6 5 0,000 5,065E-03 0,04528738 ! brown fat cell differentiation GO:0050873 5 5 0,000 5,065E-03 0,04517665 ! regulation of telomerase activity GO:0051972 6 5 0,000 5,065E-03 0,04506646 ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 5,065E-03 0,04495681 ! TAP complex GO:0042825 5 5 0,000 5,065E-03 0,04484769 ! platelet dense granule GO:0042827 6 5 0,000 5,065E-03 0,0447391 ! bHLH transcription factor binding GO:0043425 5 5 0,000 5,065E-03 0,04463104 ! secretory granule organization GO:0033363 5 5 0,000 5,065E-03 0,04452349 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 14 5 0,000 5,065E-03 0,04441646 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 5,065E-03 0,04430995 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 5,065E-03 0,04420395 ! lamin binding GO:0005521 8 5 0,000 5,065E-03 0,04409845 ! aldehyde-lyase activity GO:0016832 6 5 0,000 5,065E-03 0,04399345 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 5,065E-03 0,04388895 ! neural plate morphogenesis GO:0001839 6 5 0,000 5,065E-03 0,04378495 ! cyclosporin A binding GO:0016018 6 5 0,000 5,065E-03 0,04368144 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 5,065E-03 0,04357842 ! negative regulation of fibrinolysis GO:0051918 5 5 0,000 5,065E-03 0,04347588 ! positive regulation of telomere maintenance GO:0032206 7 5 0,000 5,065E-03 0,04337382 ! pattern recognition receptor signaling pathway GO:0002221 5 5 0,000 5,065E-03 0,04327225 GO:0002224|toll-like receptor signaling pathway, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 5 5 0,000 5,065E-03 0,04317114 ! positive regulation of blood vessel endothelial cell migration GO:0043536 6 5 0,000 5,065E-03 0,04307051 ! flavin-containing monooxygenase activity GO:0004499 6 5 0,000 5,065E-03 0,04297035 ! regulation of calcium ion transport via store-operated calcium channel activity GO:0032234 5 5 0,000 5,065E-03 0,04287065 ! hemopoietic progenitor cell differentiation GO:0002244 6 5 0,000 5,065E-03 0,04277141 ! organ or tissue specific immune response GO:0002251 6 5 0,000 5,065E-03 0,04267263 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 5,065E-03 0,04257431 ! retina homeostasis GO:0001895 5 5 0,000 5,065E-03 0,04247644 ! prepulse inhibition GO:0060134 8 5 0,000 5,065E-03 0,04237901 ! maternal placenta development GO:0001893 5 5 0,000 5,065E-03 0,04228204 GO:0046697|decidualization, ! endothelial cell development GO:0001885 6 5 0,000 5,065E-03 0,0421855 ! regulation of growth hormone secretion GO:0060123 5 5 0,000 5,065E-03 0,04208941 GO:0060124|positive regulation of growth hormone secretion, ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 5,065E-03 0,04199375 ! thiamin pyrophosphate binding GO:0030976 5 5 0,000 5,065E-03 0,04189852 ! protein palmitoylation GO:0018345 5 5 0,000 5,065E-03 0,04180373 ! protein amino acid prenylation GO:0018346 6 5 0,000 5,065E-03 0,04170937 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 5 0,000 5,065E-03 0,04161543 ! stem cell division GO:0017145 6 5 0,000 5,065E-03 0,04152191 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 5,065E-03 0,04142881 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 6 5 0,000 5,065E-03 0,04133613 ! organ regeneration GO:0031100 6 5 0,000 5,065E-03 0,04124386 ! lymphocyte apoptosis GO:0070227 6 5 0,000 5,065E-03 0,041152 ! positive regulation of microtubule polymerization GO:0031116 5 5 0,000 5,065E-03 0,04106055 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 5,065E-03 0,04096951 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of developmental growth GO:0048639 6 5 0,000 5,065E-03 0,04087887 ! acyl carrier activity GO:0000036 5 5 0,000 5,065E-03 0,04078863 ! positive regulation of cAMP biosynthetic process GO:0030819 6 5 0,000 5,065E-03 0,04069879 GO:0030816|positive regulation of cAMP metabolic process, ! condensin complex GO:0000796 6 5 0,000 5,065E-03 0,04060934 ! phagocytic vesicle GO:0045335 5 5 0,000 5,065E-03 0,04052028 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 5,065E-03 0,04043162 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 5,065E-03 0,04034334 GO:0030823|regulation of cGMP metabolic process, ! citrulline metabolic process GO:0000052 14 5 0,000 5,065E-03 0,04025545 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 5,065E-03 0,04016793 ! polyol transport GO:0015791 8 5 0,000 5,065E-03 0,0400808 ! post-embryonic morphogenesis GO:0009886 7 5 0,000 5,065E-03 0,03999405 ! pyrimidine nucleotide-sugar transport GO:0015781 5 5 0,000 5,065E-03 0,03990767 ! regulation of cell adhesion mediated by integrin GO:0033628 5 5 0,000 5,065E-03 0,03982166 ! cell adhesion mediated by integrin GO:0033627 5 5 0,000 5,065E-03 0,03973602 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 5,065E-03 0,03965075 ! glycerol-3-phosphate metabolic process GO:0006072 6 5 0,000 5,065E-03 0,03956584 ! ethanol metabolic process GO:0006067 6 5 0,000 5,065E-03 0,0394813 GO:0006069|ethanol oxidation, GO:0034308|monohydric alcohol metabolic process, ! phosphatidic acid metabolic process GO:0046473 5 5 0,000 5,065E-03 0,03939712 ! cobalt ion transport GO:0006824 5 5 0,000 5,065E-03 0,0393133 ! cellular zinc ion homeostasis GO:0006882 6 5 0,000 5,065E-03 0,03922983 ! Golgi to plasma membrane transport GO:0006893 7 5 0,000 5,065E-03 0,03914671 ! syncytium formation by plasma membrane fusion GO:0000768 5 5 0,000 5,065E-03 0,03906395 GO:0007520|myoblast fusion, ! poly(U) RNA binding GO:0008266 5 5 0,000 5,065E-03 0,03898154 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 5 5 0,000 5,065E-03 0,03889947 ! sterol carrier activity GO:0005498 6 5 0,000 5,065E-03 0,03881775 ! adaptation of signaling pathway GO:0022401 6 5 0,000 5,065E-03 0,03873637 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 6 5 0,000 5,065E-03 0,03865533 ! response to acid GO:0001101 7 5 0,000 5,065E-03 0,03857463 ! fibril organization GO:0043206 5 5 0,000 5,065E-03 0,03849427 ! malate metabolic process GO:0006108 6 5 0,000 5,065E-03 0,03841424 ! regulation of dopamine uptake GO:0051584 7 5 0,000 5,065E-03 0,03833454 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! copulation GO:0007620 5 5 0,000 5,065E-03 0,03825517 ! circadian sleep/wake cycle process GO:0022410 5 5 0,000 5,065E-03 0,03817614 GO:0042749|regulation of circadian sleep/wake cycle, GO:0045187|regulation of circadian sleep/wake cycle, sleep, ! cleavage furrow GO:0032154 6 5 0,000 5,065E-03 0,03809742 ! protein maturation by protein folding GO:0022417 5 5 0,000 5,065E-03 0,03801903 ! activation of protein kinase B activity GO:0032148 15 5 0,000 5,065E-03 0,03794096 ! origin recognition complex GO:0000808 5 5 0,000 5,065E-03 0,03786322 ! neurexin binding GO:0042043 6 5 0,000 5,065E-03 0,03778579 ! sensory perception of temperature stimulus GO:0050951 8 5 0,000 5,065E-03 0,03770867 ! protein amino acid dealkylation GO:0008214 5 5 0,000 5,065E-03 0,03763187 GO:0006482|protein amino acid demethylation, ! NF-kappaB-inducing kinase activity GO:0004704 5 5 0,000 5,065E-03 0,03755538 ! lipoic acid binding GO:0031405 5 5 0,000 5,065E-03 0,03747921 ! very-low-density lipoprotein particle assembly GO:0034379 5 5 0,000 5,065E-03 0,03740334 ! lithium ion binding GO:0031403 6 5 0,000 5,065E-03 0,03732778 ! grooming behavior GO:0007625 7 5 0,000 5,065E-03 0,03725252 ! regulation of smooth muscle cell apoptosis GO:0034391 5 5 0,000 5,065E-03 0,03717756 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 5,065E-03 0,03710291 ! lymph vessel development GO:0001945 6 5 0,000 5,065E-03 0,03702856 ! bicarbonate transport GO:0015701 5 5 0,000 5,065E-03 0,0369545 ! response to interferon-gamma GO:0034341 6 5 0,000 5,065E-03 0,03688074 ! protein-lysine 6-oxidase activity GO:0004720 23 5 0,000 5,065E-03 0,03680727 ! endothelial cell proliferation GO:0001935 8 5 0,000 5,065E-03 0,03673409 ! polynucleotide adenylyltransferase activity GO:0004652 5 5 0,000 5,065E-03 0,03666121 ! dorsal spinal cord development GO:0021516 6 5 0,000 5,065E-03 0,03658861 ! activation of MAPKKK activity GO:0000185 5 5 0,000 5,065E-03 0,0365163 ! synaptic vesicle maturation GO:0016188 6 5 0,000 5,065E-03 0,03644428 ! sphingoid catabolic process GO:0046521 5 5 0,000 5,065E-03 0,03637254 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 5,065E-03 0,03630108 ! neutrophil mediated immunity GO:0002446 5 5 0,000 5,065E-03 0,0362299 ! intercellular canaliculus GO:0046581 5 5 0,000 5,065E-03 0,036159 ! dopamine binding GO:0035240 7 5 0,000 5,065E-03 0,03608838 GO:0004952|dopamine receptor activity, ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 5 5 0,000 5,065E-03 0,03601803 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 5 5 0,000 5,065E-03 0,03594796 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 6 5 0,000 5,065E-03 0,03587815 ! amine oxidase activity GO:0008131 7 5 0,000 5,065E-03 0,03580862 ! monocyte activation GO:0042117 9 5 0,000 5,065E-03 0,03573936 ! negative regulation of protein binding GO:0032091 5 5 0,000 5,065E-03 0,03567037 ! regulation of response to food GO:0032095 5 5 0,000 5,065E-03 0,03560164 ! response to food GO:0032094 6 5 0,000 5,065E-03 0,03553317 ! positive regulation of protein binding GO:0032092 5 5 0,000 5,065E-03 0,03546497 ! copper ion transmembrane transporter activity GO:0005375 5 5 0,000 5,065E-03 0,03539703 ! regulation of ryanodine-sensitive calcium-release channel activity GO:0060314 6 5 0,000 5,065E-03 0,03532935 ! hedgehog receptor activity GO:0008158 5 5 0,000 5,065E-03 0,03526193 ! lipoprotein catabolic process GO:0042159 5 5 0,000 5,065E-03 0,03519476 ! substrate-bound cell migration, cell extension GO:0006930 7 5 0,000 5,065E-03 0,03512785 ! purine salvage GO:0043101 7 5 0,000 5,065E-03 0,03506119 ! small-subunit processome GO:0032040 5 5 0,000 5,065E-03 0,03499479 ! positive regulation of catecholamine secretion GO:0033605 5 5 0,000 5,065E-03 0,03492864 ! ciliary rootlet GO:0035253 5 5 0,000 5,065E-03 0,03486273 ! myosin heavy chain binding GO:0032036 5 5 0,000 5,065E-03 0,03479708 ! nucleobase transport GO:0015851 5 5 0,000 5,065E-03 0,03473167 ! sodium ion transmembrane transporter activity GO:0015081 6 5 0,000 5,065E-03 0,03466651 ! GPI anchor binding GO:0034235 6 5 0,000 5,065E-03 0,03460159 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,065E-03 0,03453691 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! thrombin receptor activity GO:0015057 5 5 0,000 5,065E-03 0,03447248 ! palmitoyl-CoA hydrolase activity GO:0016290 5 5 0,000 5,065E-03 0,03440829 ! basic amino acid transport GO:0015802 5 5 0,000 5,065E-03 0,03434433 ! dendritic shaft GO:0043198 5 5 0,000 5,065E-03 0,03428061 ! terminal button GO:0043195 7 5 0,000 5,065E-03 0,03421713 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 5,065E-03 0,03415388 GO:0016274|protein-arginine N-methyltransferase activity, ! neuronal ion channel clustering GO:0045161 5 5 0,000 5,065E-03 0,03409087 ! transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity GO:0030618 6 5 0,000 5,065E-03 0,03402808 ! homeostasis of number of cells within a tissue GO:0048873 7 5 0,000 5,065E-03 0,03396553 ! negative regulation of peptide secretion GO:0002792 5 5 0,000 5,065E-03 0,03390321 GO:0046676|negative regulation of insulin secretion, ! neural nucleus development GO:0048857 6 5 0,000 5,065E-03 0,03384112 ! response to UV-C GO:0010225 15 5 0,000 5,065E-03 0,03377925 ! positive regulation of organ growth GO:0046622 5 5 0,000 5,065E-03 0,03371761 ! response to arsenic GO:0046685 6 5 0,000 5,065E-03 0,03365619 ! IgE binding GO:0019863 5 5 0,000 5,065E-03 0,033595 ! positive regulation of T cell cytokine production GO:0002726 5 5 0,000 5,065E-03 0,03353403 GO:0032743|positive regulation of interleukin-2 production, ! transcription-coupled nucleotide-excision repair GO:0006283 5 5 0,000 5,065E-03 0,03347328 ! monoamine transmembrane transporter activity GO:0008504 6 5 0,000 5,065E-03 0,03341275 ! response to copper ion GO:0046688 5 5 0,000 5,065E-03 0,03335244 ! response to cadmium ion GO:0046686 5 5 0,000 5,065E-03 0,03329234 ! tetrahydrofolate metabolic process GO:0046653 5 5 0,000 5,065E-03 0,03323246 ! regulation of interleukin-1 beta production GO:0032651 5 5 0,000 5,065E-03 0,0331728 ! protein autoprocessing GO:0016540 6 5 0,000 5,065E-03 0,03311335 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 5,065E-03 0,03305411 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 5,065E-03 0,03299509 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 5,065E-03 0,03293627 GO:0005218|intracellular ligand-gated calcium channel activity, ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 5,065E-03 0,03287767 ! mitotic recombination GO:0006312 15 5 0,000 5,065E-03 0,03281927 ! negative regulation of interleukin-6 production GO:0032715 6 5 0,000 5,065E-03 0,03276108 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 5,065E-03 0,0327031 ! membrane to membrane docking GO:0022614 5 5 0,000 5,065E-03 0,03264532 ! regulation of transcription from RNA polymerase I promoter GO:0006356 14 5 0,000 5,065E-03 0,03258774 ! translation activator activity GO:0008494 5 5 0,000 5,065E-03 0,03253037 ! somatostatin receptor activity GO:0004994 5 5 0,000 5,065E-03 0,0324732 ! melanocortin receptor activity GO:0004977 6 5 0,000 5,065E-03 0,03241623 ! serine-type carboxypeptidase activity GO:0004185 5 5 0,000 5,065E-03 0,03235946 GO:0070008|serine-type exopeptidase activity, ! protein phosphatase 2A binding GO:0051721 6 5 0,000 5,065E-03 0,03230288 ! salivary gland morphogenesis GO:0007435 5 5 0,000 5,065E-03 0,03224651 ! galactosidase activity GO:0015925 5 5 0,000 5,065E-03 0,03219033 ! prostaglandin E receptor activity GO:0004957 7 5 0,000 5,065E-03 0,03213435 ! cellular response to nutrient GO:0031670 5 5 0,000 5,065E-03 0,03207856 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 5,065E-03 0,03202296 ! L-cystine transmembrane transporter activity GO:0015184 5 5 0,000 5,065E-03 0,03196756 ! glycine transmembrane transporter activity GO:0015187 7 5 0,000 5,065E-03 0,03191235 ! L-gamma-aminobutyric acid transmembrane transporter activity GO:0015185 6 5 0,000 5,065E-03 0,03185733 ! A band GO:0031672 5 5 0,000 5,065E-03 0,03180249 ! heat generation GO:0031649 5 5 0,000 5,065E-03 0,03174785 ! flagellum organization GO:0043064 5 5 0,000 5,065E-03 0,0316934 GO:0009296|flagellum assembly, ! tricarboxylic acid cycle enzyme complex GO:0045239 6 5 0,000 5,065E-03 0,03163913 ! disaccharide metabolic process GO:0005984 6 5 0,000 5,065E-03 0,03158504 ! glycogen catabolic process GO:0005980 16 5 0,000 5,065E-03 0,03153114 ! dopamine biosynthetic process GO:0042416 6 5 0,000 5,065E-03 0,03147743 ! 5'-3' exonuclease activity GO:0008409 14 5 0,000 5,065E-03 0,03142389 ! chromocenter GO:0010369 5 5 0,000 5,065E-03 0,03137054 ! glial cell migration GO:0008347 5 5 0,000 5,065E-03 0,03131737 ! epidermal growth factor receptor binding GO:0005154 7 5 0,000 5,065E-03 0,03126438 ! calcium-dependent phospholipase A2 activity GO:0047498 5 5 0,000 5,065E-03 0,03121157 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 5,065E-03 0,03115894 ! growth hormone receptor binding GO:0005131 5 5 0,000 5,065E-03 0,03110648 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 5,065E-03 0,0310542 ! negative regulation of smooth muscle contraction GO:0045986 7 5 0,000 5,065E-03 0,0310021 ! aminomethyltransferase activity GO:0004047 5 5 0,000 5,065E-03 0,03095017 ! aminoacylase activity GO:0004046 5 5 0,000 5,065E-03 0,03089841 ! penetration of zona pellucida GO:0007341 6 5 0,000 5,065E-03 0,03084683 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 5 5 0,000 5,065E-03 0,03079542 ! nucleus localization GO:0051647 5 5 0,000 5,065E-03 0,03074418 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 5 5 0,000 5,065E-03 0,03069311 ! carnitine metabolic process GO:0009437 5 5 0,000 5,065E-03 0,0306422 GO:0006577|betaine metabolic process, ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 6,075E-03 0,03669213 ! regulation of helicase activity GO:0051095 6 6 0,000 6,075E-03 0,03663148 ! response to oxygen radical GO:0000305 6 6 0,000 6,075E-03 0,03657103 ! positive regulation of axon extension GO:0045773 7 6 0,000 6,075E-03 0,03651078 ! forebrain neuron differentiation GO:0021879 6 6 0,000 6,075E-03 0,03645073 ! forebrain regionalization GO:0021871 7 6 0,000 6,075E-03 0,03639088 ! meiotic prophase I GO:0007128 7 6 0,000 6,075E-03 0,03633122 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 6,075E-03 0,03627176 ! inositol trisphosphate phosphatase activity GO:0046030 8 6 0,000 6,075E-03 0,03621249 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 6,075E-03 0,03615342 ! SMAD protein nuclear translocation GO:0007184 7 6 0,000 6,075E-03 0,03609453 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 9 6 0,000 6,075E-03 0,03603584 ! carbohydrate phosphorylation GO:0046835 7 6 0,000 6,075E-03 0,03597734 ! phosphoinositide 3-kinase binding GO:0043548 6 6 0,000 6,075E-03 0,03591903 ! protein amino acid sulfation GO:0006477 9 6 0,000 6,075E-03 0,03586091 GO:0051923|sulfation, ! diphosphotransferase activity GO:0016778 7 6 0,000 6,075E-03 0,03580298 ! establishment of tissue polarity GO:0007164 8 6 0,000 6,075E-03 0,03574523 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 6,075E-03 0,03568767 ! receptor guanylyl cyclase signaling pathway GO:0007168 6 6 0,000 6,075E-03 0,0356303 ! embryonic camera-type eye development GO:0031076 9 6 0,000 6,075E-03 0,0355731 GO:0048596|embryonic camera-type eye morphogenesis, ! hexokinase activity GO:0004396 7 6 0,000 6,075E-03 0,0355161 ! regulation of mitochondrial membrane permeability GO:0046902 7 6 0,000 6,075E-03 0,03545927 ! neurofilament cytoskeleton organization GO:0060052 6 6 0,000 6,075E-03 0,03540263 ! Notch receptor processing GO:0007220 7 6 0,000 6,075E-03 0,03534616 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 8 6 0,000 6,075E-03 0,03528988 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 7 6 0,000 6,075E-03 0,03523377 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 6,075E-03 0,03517785 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 6,075E-03 0,0351221 ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 6 0,000 6,075E-03 0,03506653 ! neurofilament GO:0005883 7 6 0,000 6,075E-03 0,03501113 ! glial cell fate commitment GO:0021781 7 6 0,000 6,075E-03 0,03495591 ! cytoplasmic dynein complex GO:0005868 7 6 0,000 6,075E-03 0,03490086 ! dynactin complex GO:0005869 7 6 0,000 6,075E-03 0,03484598 ! fibroblast growth factor receptor antagonist activity GO:0030353 7 6 0,000 6,075E-03 0,03479128 GO:0005152|interleukin-1 receptor antagonist activity, ! enoyl-CoA hydratase activity GO:0004300 6 6 0,000 6,075E-03 0,03473675 ! oocyte maturation GO:0001556 6 6 0,000 6,075E-03 0,03468239 ! DNA replication origin binding GO:0003688 6 6 0,000 6,075E-03 0,03462819 ! reflex GO:0060004 10 6 0,000 6,075E-03 0,03457417 ! positive regulation of glycolysis GO:0045821 6 6 0,000 6,075E-03 0,03452032 ! parathyroid gland development GO:0060017 6 6 0,000 6,075E-03 0,03446663 ! anagen GO:0042640 7 6 0,000 6,075E-03 0,03441311 ! protein-cofactor linkage GO:0018065 15 6 0,000 6,075E-03 0,03435976 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 6 6 0,000 6,075E-03 0,03430657 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! protein targeting to ER GO:0045047 7 6 0,000 6,075E-03 0,03425355 GO:0006614|SRP-dependent cotranslational protein targeting to membrane, ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 6 6 0,000 6,075E-03 0,03420069 ! skeletal myofibril assembly GO:0014866 6 6 0,000 6,075E-03 0,03414799 ! structural constituent of tooth enamel GO:0030345 7 6 0,000 6,075E-03 0,03409545 ! cysteine metabolic process GO:0006534 7 6 0,000 6,075E-03 0,03404308 ! glycine catabolic process GO:0006546 6 6 0,000 6,075E-03 0,03399087 ! adenohypophysis development GO:0021984 6 6 0,000 6,075E-03 0,03393881 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 6 6 0,000 6,075E-03 0,03388692 ! deoxyribonucleotide biosynthetic process GO:0009263 7 6 0,000 6,075E-03 0,03383518 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 6 0,000 6,075E-03 0,0337836 ! proline biosynthetic process GO:0006561 8 6 0,000 6,075E-03 0,03373218 ! tryptophan metabolic process GO:0006568 6 6 0,000 6,075E-03 0,03368092 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 6 6 0,000 6,075E-03 0,03362981 ! thyroid hormone generation GO:0006590 6 6 0,000 6,075E-03 0,03357885 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 6,075E-03 0,03352805 ! retinoid X receptor binding GO:0046965 7 6 0,000 6,075E-03 0,03347741 ! proton-transporting V-type ATPase, V0 domain GO:0033179 6 6 0,000 6,075E-03 0,03342691 ! transforming growth factor beta receptor activity, type I GO:0005025 7 6 0,000 6,075E-03 0,03337657 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 6,075E-03 0,03332638 ! sister chromatid cohesion GO:0007062 6 6 0,000 6,075E-03 0,03327634 ! retinoic acid receptor signaling pathway GO:0048384 9 6 0,000 6,075E-03 0,03322645 ! positive regulation of transporter activity GO:0032411 8 6 0,000 6,075E-03 0,03317671 GO:0032414|positive regulation of ion transmembrane transporter activity, ! cerebral cortex neuron differentiation GO:0021895 7 6 0,000 6,075E-03 0,03312712 ! regulation of fatty acid beta-oxidation GO:0031998 6 6 0,000 6,075E-03 0,03307768 ! p53 binding GO:0002039 6 6 0,000 6,075E-03 0,03302838 ! demethylase activity GO:0032451 6 6 0,000 6,075E-03 0,03297923 ! positive regulation of nitric-oxide synthase activity GO:0051000 6 6 0,000 6,075E-03 0,03293023 ! regulation of platelet activation GO:0010543 7 6 0,000 6,075E-03 0,03288137 ! lipid phosphatase activity GO:0042577 7 6 0,000 6,075E-03 0,03283266 ! lens morphogenesis in camera-type eye GO:0002089 6 6 0,000 6,075E-03 0,03278409 ! guanylate cyclase activator activity GO:0030250 6 6 0,000 6,075E-03 0,03273566 GO:0010853|cyclase activator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 8 6 0,000 6,075E-03 0,03268738 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of exocytosis GO:0045921 6 6 0,000 6,075E-03 0,03263924 ! protein tyrosine kinase activator activity GO:0030296 8 6 0,000 6,075E-03 0,03259124 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 6,075E-03 0,03254338 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of steroid metabolic process GO:0045940 6 6 0,000 6,075E-03 0,03249567 ! LIM domain binding GO:0030274 7 6 0,000 6,075E-03 0,03244809 ! negative regulation of translational initiation GO:0045947 6 6 0,000 6,075E-03 0,03240065 ! positive regulation vascular endothelial growth factor production GO:0010575 6 6 0,000 6,075E-03 0,03235335 ! 5S class rRNA transcription GO:0042791 6 6 0,000 6,075E-03 0,03230619 GO:0042797|tRNA transcription from RNA polymerase III promoter, GO:0000127|transcription factor TFIIIC complex, ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 6,075E-03 0,03225916 ! axon guidance receptor activity GO:0008046 6 6 0,000 6,075E-03 0,03221227 ! zinc ion homeostasis GO:0055069 7 6 0,000 6,075E-03 0,03216552 ! positive regulation of gliogenesis GO:0014015 7 6 0,000 6,075E-03 0,0321189 GO:0045687|positive regulation of glial cell differentiation, ! centrosome duplication GO:0051298 7 6 0,000 6,075E-03 0,03207242 ! protein targeting to lysosome GO:0006622 6 6 0,000 6,075E-03 0,03202608 ! hyaluronan metabolic process GO:0030212 8 6 0,000 6,075E-03 0,03197986 ! protein retention in ER lumen GO:0006621 6 6 0,000 6,075E-03 0,03193378 ! ventricular cardiac muscle cell differentiation GO:0055012 8 6 0,000 6,075E-03 0,03188783 ! circadian sleep/wake cycle GO:0042745 7 6 0,000 6,075E-03 0,03184202 ! dynein binding GO:0045502 6 6 0,000 6,075E-03 0,03179633 ! regulation of dendrite development GO:0050773 6 6 0,000 6,075E-03 0,03175078 ! peptidyl-arginine modification GO:0018195 6 6 0,000 6,075E-03 0,03170536 ! eating behavior GO:0042755 7 6 0,000 6,075E-03 0,03166006 ! protein localization to chromosome GO:0034502 8 6 0,000 6,075E-03 0,0316149 ! Hsp90 protein binding GO:0051879 7 6 0,000 6,075E-03 0,03156986 ! glycolipid binding GO:0051861 7 6 0,000 6,075E-03 0,03152496 ! MutLalpha complex binding GO:0032405 8 6 0,000 6,075E-03 0,03148018 ! mast cell activation GO:0045576 6 6 0,000 6,075E-03 0,03143552 ! nucleoside catabolic process GO:0009164 7 6 0,000 6,075E-03 0,031391 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 6,075E-03 0,0313466 ! molybdopterin cofactor biosynthetic process GO:0032324 15 6 0,000 6,075E-03 0,03130232 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 6,075E-03 0,03125817 ! RNA polymerase II transcription elongation factor activity GO:0016944 6 6 0,000 6,075E-03 0,03121415 ! lipoxygenase activity GO:0016165 6 6 0,000 6,075E-03 0,03117024 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 6,075E-03 0,03112647 ! alpha DNA polymerase:primase complex GO:0005658 16 6 0,000 6,075E-03 0,03108281 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 6,075E-03 0,03103928 ! DNA replication factor C complex GO:0005663 7 6 0,000 6,075E-03 0,03099587 ! DNA replication factor A complex GO:0005662 7 6 0,000 6,075E-03 0,03095258 ! establishment of chromosome localization GO:0051303 15 6 0,000 6,075E-03 0,03090941 GO:0050000|chromosome localization, ! cilium morphogenesis GO:0060271 6 6 0,000 6,075E-03 0,03086636 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 6,075E-03 0,03082343 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 6,075E-03 0,03078062 ! chromatin assembly complex GO:0005678 16 6 0,000 6,075E-03 0,03073793 ! sex chromatin GO:0001739 6 6 0,000 6,075E-03 0,03069535 GO:0000803|sex chromosome, ! morphogenesis of a polarized epithelium GO:0001738 7 6 0,000 6,075E-03 0,0306529 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 7 6 0,000 6,075E-03 0,03061056 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! SAP kinase activity GO:0016909 7 6 0,000 6,075E-03 0,03056834 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 6,075E-03 0,03052623 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 7 6 0,000 6,075E-03 0,03048424 ! positive regulation of pseudopodium assembly GO:0031274 6 6 0,000 6,075E-03 0,03044237 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipoprotein metabolic process GO:0050746 7 6 0,000 6,075E-03 0,03040061 ! phosphatidylserine binding GO:0001786 6 6 0,000 6,075E-03 0,03035896 ! alpha-mannosidase activity GO:0004559 8 6 0,000 6,075E-03 0,03031743 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 6 0,000 6,075E-03 0,03027602 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 6,075E-03 0,03023471 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 11 6 0,000 6,075E-03 0,03019352 GO:0002820|negative regulation of adaptive immune response, ! myeloid dendritic cell activation GO:0001773 8 6 0,000 6,075E-03 0,03015244 GO:0043011|myeloid dendritic cell differentiation, ! immunological synapse GO:0001772 6 6 0,000 6,075E-03 0,03011147 ! leading edge membrane GO:0031256 8 6 0,000 6,075E-03 0,03007062 ! photoreceptor connecting cilium GO:0032391 7 6 0,000 6,075E-03 0,03002987 ! CARD domain binding GO:0050700 6 6 0,000 6,075E-03 0,02998923 ! regulation of muscle cell apoptosis GO:0010660 7 6 0,000 6,075E-03 0,02994871 ! COPII vesicle coat GO:0030127 7 6 0,000 6,075E-03 0,02990829 GO:0012507|ER to Golgi transport vesicle membrane, ! molybdenum ion binding GO:0030151 15 6 0,000 6,075E-03 0,02986798 ! glutathione biosynthetic process GO:0006750 7 6 0,000 6,075E-03 0,02982778 ! positive regulation of erythrocyte differentiation GO:0045648 8 6 0,000 6,075E-03 0,02978769 ! positive regulation of epidermis development GO:0045684 8 6 0,000 6,075E-03 0,02974771 ! proteasome regulator activity GO:0010860 6 6 0,000 6,075E-03 0,02970783 ! ceramidase activity GO:0017040 6 6 0,000 6,075E-03 0,02966806 ! antibiotic transport GO:0042891 7 6 0,000 6,075E-03 0,0296284 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 6,075E-03 0,02958884 ! regulation of T-helper cell differentiation GO:0045622 6 6 0,000 6,075E-03 0,02954939 ! sodium channel regulator activity GO:0017080 6 6 0,000 6,075E-03 0,02951005 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 6,075E-03 0,0294708 ! regulation of protein homodimerization activity GO:0043496 9 6 0,000 6,075E-03 0,02943167 ! response to fluid shear stress GO:0034405 6 6 0,000 6,075E-03 0,02939263 ! lymph node development GO:0048535 6 6 0,000 6,075E-03 0,0293537 ! negative regulation of viral reproduction GO:0048525 7 6 0,000 6,075E-03 0,02931487 ! triglyceride catabolic process GO:0019433 15 6 0,000 6,075E-03 0,02927615 ! positive regulation of fatty acid oxidation GO:0046321 6 6 0,000 6,075E-03 0,02923753 ! ectodermal gut morphogenesis GO:0048567 7 6 0,000 6,075E-03 0,029199 GO:0007439|ectodermal gut development, ! T cell activation during immune response GO:0002286 6 6 0,000 6,075E-03 0,02916058 ! negative regulation of lipase activity GO:0060192 6 6 0,000 6,075E-03 0,02912227 ! activation of innate immune response GO:0002218 6 6 0,000 6,075E-03 0,02908405 GO:0002758|innate immune response-activating signal transduction, ! regulation of telomere maintenance via telomerase GO:0032210 7 6 0,000 6,075E-03 0,02904593 ! sarcoglycan complex GO:0016012 8 6 0,000 6,075E-03 0,02900791 ! natural killer cell mediated immunity GO:0002228 7 6 0,000 6,075E-03 0,02896999 GO:0042267|natural killer cell mediated cytotoxicity, ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 6 6 0,000 6,075E-03 0,02893217 ! neural plate development GO:0001840 7 6 0,000 6,075E-03 0,02889445 ! regulation of synaptic transmission, GABAergic GO:0032228 15 6 0,000 6,075E-03 0,02885683 ! catecholamine transport GO:0051937 6 6 0,000 6,075E-03 0,0288193 ! ether hydrolase activity GO:0016803 7 6 0,000 6,075E-03 0,02878188 ! FACIT collagen GO:0005593 6 6 0,000 6,075E-03 0,02874454 ! lactate dehydrogenase activity GO:0004457 6 6 0,000 6,075E-03 0,02870731 ! regulation of T cell receptor signaling pathway GO:0050856 7 6 0,000 6,075E-03 0,02867017 ! collagen type IV GO:0005587 6 6 0,000 6,075E-03 0,02863313 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 6,075E-03 0,02859619 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 7 6 0,000 6,075E-03 0,02855934 ! drug metabolic process GO:0017144 6 6 0,000 6,075E-03 0,02852258 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 6,075E-03 0,02848592 ! negative regulation of synaptic transmission GO:0050805 6 6 0,000 6,075E-03 0,02844935 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 6,075E-03 0,02841288 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 6,075E-03 0,0283765 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 6 6 0,000 6,075E-03 0,02834021 ! regulation of microtubule polymerization GO:0031113 6 6 0,000 6,075E-03 0,02830402 ! cellular anion homeostasis GO:0030002 6 6 0,000 6,075E-03 0,02826791 GO:0055081|anion homeostasis, ! regulation of MHC class II biosynthetic process GO:0045346 6 6 0,000 6,075E-03 0,0282319 ! negative regulation of fibroblast proliferation GO:0048147 6 6 0,000 6,075E-03 0,02819598 ! behavioral response to cocaine GO:0048148 9 6 0,000 6,075E-03 0,02816016 ! translation initiation factor binding GO:0031369 6 6 0,000 6,075E-03 0,02812442 ! nucleotide-sugar transport GO:0015780 6 6 0,000 6,075E-03 0,02808878 ! sulfur amino acid transmembrane transporter activity GO:0000099 6 6 0,000 6,075E-03 0,02805322 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 6,075E-03 0,02801775 ! quaternary ammonium group binding GO:0050997 7 6 0,000 6,075E-03 0,02798238 ! actin-dependent ATPase activity GO:0030898 7 6 0,000 6,075E-03 0,02794709 ! reproductive behavior GO:0019098 8 6 0,000 6,075E-03 0,02791189 ! response to growth hormone stimulus GO:0060416 7 6 0,000 6,075E-03 0,02787678 GO:0060396|growth hormone receptor signaling pathway, ! negative regulation of JAK-STAT cascade GO:0046426 8 6 0,000 6,075E-03 0,02784176 ! nucleotide-excision repair, DNA incision GO:0033683 6 6 0,000 6,075E-03 0,02780683 ! negative regulation of cell-cell adhesion GO:0022408 8 6 0,000 6,075E-03 0,02777198 ! positive regulation of cell-cell adhesion GO:0022409 7 6 0,000 6,075E-03 0,02773723 ! induction of positive chemotaxis GO:0050930 7 6 0,000 6,075E-03 0,02770256 ! cohesin complex GO:0008278 6 6 0,000 6,075E-03 0,02766797 ! regulation of collagen biosynthetic process GO:0032965 7 6 0,000 6,075E-03 0,02763347 ! citrate metabolic process GO:0006101 7 6 0,000 6,075E-03 0,02759906 ! myelin sheath GO:0043209 8 6 0,000 6,075E-03 0,02756473 ! phototransduction, visible light GO:0007603 6 6 0,000 6,075E-03 0,02753049 ! opsonization GO:0008228 7 6 0,000 6,075E-03 0,02749633 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 6,075E-03 0,02746226 ! regulation of dopamine metabolic process GO:0042053 8 6 0,000 6,075E-03 0,02742827 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 7 6 0,000 6,075E-03 0,02739437 ! regulation of potassium ion transport GO:0043266 8 6 0,000 6,075E-03 0,02736055 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 6,075E-03 0,02732681 ! chemoattractant activity GO:0042056 6 6 0,000 6,075E-03 0,02729316 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 8 6 0,000 6,075E-03 0,02725959 ! low-density lipoprotein particle remodeling GO:0034374 6 6 0,000 6,075E-03 0,0272261 ! ornithine decarboxylase regulator activity GO:0042979 6 6 0,000 6,075E-03 0,02719269 ! leukocyte degranulation GO:0043299 6 6 0,000 6,075E-03 0,02715937 ! bile acid and bile salt transport GO:0015721 7 6 0,000 6,075E-03 0,02712612 ! regulation of cytokine-mediated signaling pathway GO:0001959 11 6 0,000 6,075E-03 0,02709296 ! mitochondrial genome maintenance GO:0000002 6 6 0,000 6,075E-03 0,02705988 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 6 0,000 6,075E-03 0,02702688 ! DNA topoisomerase activity GO:0003916 6 6 0,000 6,075E-03 0,02699396 ! protein geranylgeranyltransferase activity GO:0004661 7 6 0,000 6,075E-03 0,02696112 ! ceramide biosynthetic process GO:0046513 6 6 0,000 6,075E-03 0,02692836 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 6,075E-03 0,02689568 ! activin receptor activity GO:0017002 7 6 0,000 6,075E-03 0,02686308 ! astrocyte differentiation GO:0048708 6 6 0,000 6,075E-03 0,02683056 ! syncytium formation GO:0006949 6 6 0,000 6,075E-03 0,02679812 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 6,075E-03 0,02676575 ! neutrophil activation GO:0042119 6 6 0,000 6,075E-03 0,02673347 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 6,075E-03 0,02670126 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 6,075E-03 0,02666913 ! positive regulation of activated T cell proliferation GO:0042104 7 6 0,000 6,075E-03 0,02663707 ! positive transcription elongation factor activity GO:0008159 7 6 0,000 6,075E-03 0,02660509 ! NuA4 histone acetyltransferase complex GO:0035267 8 6 0,000 6,075E-03 0,02657319 ! cellular polysaccharide catabolic process GO:0044247 17 6 0,000 6,075E-03 0,02654137 GO:0009251|glucan catabolic process, ! response to salt stress GO:0009651 7 6 0,000 6,075E-03 0,02650962 ! neuron apoptosis GO:0051402 7 6 0,000 6,075E-03 0,02647795 ! folic acid transport GO:0015884 8 6 0,000 6,075E-03 0,02644635 ! carnitine transport GO:0015879 6 6 0,000 6,075E-03 0,02641483 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 6,075E-03 0,02638339 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! parturition GO:0007567 7 6 0,000 6,075E-03 0,02635201 ! S-methyltransferase activity GO:0008172 6 6 0,000 6,075E-03 0,02632072 ! phospholipase D activity GO:0004630 6 6 0,000 6,075E-03 0,02628949 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 6,075E-03 0,02625835 ! intercalated disc GO:0014704 8 6 0,000 6,075E-03 0,02622727 ! G2/M transition checkpoint GO:0031576 24 6 0,000 6,075E-03 0,02619627 GO:0031572|G2/M transition DNA damage checkpoint, ! interaction with symbiont GO:0051702 6 6 0,000 6,075E-03 0,02616534 ! IgG binding GO:0019864 6 6 0,000 6,075E-03 0,02613449 ! regulation of T cell cytokine production GO:0002724 6 6 0,000 6,075E-03 0,0261037 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 6 6 0,000 6,075E-03 0,02607299 ! benzodiazepine receptor activity GO:0008503 7 6 0,000 6,075E-03 0,02604235 ! antigen processing and presentation of exogenous antigen GO:0019884 7 6 0,000 6,075E-03 0,02601179 ! regulation of T cell differentiation in the thymus GO:0033081 7 6 0,000 6,075E-03 0,02598129 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 6 6 0,000 6,075E-03 0,02595087 ! regulation of interleukin-4 production GO:0032673 6 6 0,000 6,075E-03 0,02592052 ! dendrite morphogenesis GO:0048813 7 6 0,000 6,075E-03 0,02589024 ! regulation of interleukin-1 production GO:0032652 7 6 0,000 6,075E-03 0,02586003 ! ribosomal large subunit biogenesis GO:0042273 7 6 0,000 6,075E-03 0,02582989 ! regulation of myeloid cell apoptosis GO:0033032 8 6 0,000 6,075E-03 0,02579982 ! nucleosome disassembly GO:0006337 7 6 0,000 6,075E-03 0,02576982 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! general transcriptional repressor activity GO:0016565 7 6 0,000 6,075E-03 0,02573989 ! regulation of mast cell activation GO:0033003 6 6 0,000 6,075E-03 0,02571003 ! tetracycline transporter activity GO:0008493 7 6 0,000 6,075E-03 0,02568024 GO:0042895|antibiotic transporter activity, ! guanylyltransferase activity GO:0070568 7 6 0,000 6,075E-03 0,02565051 ! receptor internalization GO:0031623 8 6 0,000 6,075E-03 0,02562086 ! N-formyl peptide receptor activity GO:0004982 6 6 0,000 6,075E-03 0,02559127 ! coenzyme A biosynthetic process GO:0015937 6 6 0,000 6,075E-03 0,02556176 ! histamine receptor activity GO:0004969 7 6 0,000 6,075E-03 0,02553231 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 6 0,000 6,075E-03 0,02550293 ! pyrimidine nucleotide sugar transmembrane transporter activity GO:0015165 6 6 0,000 6,075E-03 0,02547361 ! protein deubiquitination GO:0016579 6 6 0,000 6,075E-03 0,02544437 ! axonal fasciculation GO:0007413 7 6 0,000 6,075E-03 0,02541519 ! basic amino acid transmembrane transporter activity GO:0015174 6 6 0,000 6,075E-03 0,02538608 ! cytidine deaminase activity GO:0004126 6 6 0,000 6,075E-03 0,02535703 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 6,075E-03 0,02532805 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 6,075E-03 0,02529914 GO:0015991|ATP hydrolysis coupled proton transport, ! alpha-adrenergic receptor activity GO:0004936 9 6 0,000 6,075E-03 0,02527029 ! cytochrome-b5 reductase activity GO:0004128 7 6 0,000 6,075E-03 0,02524151 ! glycine binding GO:0016594 9 6 0,000 6,075E-03 0,02521279 ! apical protein localization GO:0045176 7 6 0,000 6,075E-03 0,02518414 ! ankyrin binding GO:0030506 6 6 0,000 6,075E-03 0,02515556 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 6,075E-03 0,02512703 ! thyroid hormone receptor activity GO:0004887 7 6 0,000 6,075E-03 0,02509858 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 6,075E-03 0,02507019 ! progesterone metabolic process GO:0042448 6 6 0,000 6,075E-03 0,02504186 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 7 6 0,000 6,075E-03 0,02501359 ! type II transforming growth factor beta receptor binding GO:0005114 6 6 0,000 6,075E-03 0,02498539 ! ATP catabolic process GO:0006200 6 6 0,000 6,075E-03 0,02495726 ! CoA carboxylase activity GO:0016421 6 6 0,000 6,075E-03 0,02492918 ! determination of adult lifespan GO:0008340 6 6 0,000 6,075E-03 0,02490117 ! S-acyltransferase activity GO:0016417 6 6 0,000 6,075E-03 0,02487323 ! somatic stem cell maintenance GO:0035019 6 6 0,000 6,075E-03 0,02484534 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 6,075E-03 0,02481752 ! IkappaB kinase complex GO:0008385 7 6 0,000 6,075E-03 0,02478976 ! nucleobase transmembrane transporter activity GO:0015205 7 6 0,000 6,075E-03 0,02476206 ! store-operated calcium channel activity GO:0015279 6 6 0,000 6,075E-03 0,02473442 ! alkaline phosphatase activity GO:0004035 7 6 0,000 6,075E-03 0,02470685 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 6 0,000 6,075E-03 0,02467934 ! unconventional myosin complex GO:0016461 8 6 0,000 6,075E-03 0,02465188 ! tRNA transcription GO:0009304 7 7 0,000 7,084E-03 0,02871477 ! respiratory burst GO:0045730 7 7 0,000 7,084E-03 0,0286829 ! telencephalon cell migration GO:0022029 8 7 0,000 7,084E-03 0,0286511 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 7,084E-03 0,02861937 ! cation:chloride symporter activity GO:0015377 8 7 0,000 7,084E-03 0,02858772 ! RNA cap binding GO:0000339 8 7 0,000 7,084E-03 0,02855613 ! generation of neurons in the forebrain GO:0021872 8 7 0,000 7,084E-03 0,02852461 ! ephrin receptor binding GO:0046875 9 7 0,000 7,084E-03 0,02849316 ! male meiosis I GO:0007141 7 7 0,000 7,084E-03 0,02846178 ! synapsis GO:0007129 7 7 0,000 7,084E-03 0,02843047 GO:0070192|chromosome organization involved in meiosis, ! insulin receptor substrate binding GO:0043560 10 7 0,000 7,084E-03 0,02839922 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 7,084E-03 0,02836805 ! type I transforming growth factor beta receptor binding GO:0034713 8 7 0,000 7,084E-03 0,02833695 ! signal peptide processing GO:0006465 7 7 0,000 7,084E-03 0,02830591 ! regulation of cardiac muscle cell proliferation GO:0060043 8 7 0,000 7,084E-03 0,02827494 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 7,084E-03 0,02824404 ! macrophage chemotaxis GO:0048246 7 7 0,000 7,084E-03 0,0282132 ! Golgi cisterna membrane GO:0032580 7 7 0,000 7,084E-03 0,02818244 ! neurofilament cytoskeleton GO:0060053 8 7 0,000 7,084E-03 0,02815174 ! positive regulation of receptor-mediated endocytosis GO:0048260 7 7 0,000 7,084E-03 0,0281211 ! smoothened signaling pathway GO:0007224 8 7 0,000 7,084E-03 0,02809054 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 7,084E-03 0,02806004 ! oxidoreductase activity, oxidizing metal ions GO:0016722 7 7 0,000 7,084E-03 0,0280296 ! cytoplasmic microtubule GO:0005881 7 7 0,000 7,084E-03 0,02799924 ! Arp2/3 protein complex GO:0005885 8 7 0,000 7,084E-03 0,02796893 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 7 7 0,000 7,084E-03 0,0279387 ! ATPase binding GO:0051117 8 7 0,000 7,084E-03 0,02790853 ! positive regulation of isotype switching GO:0045830 7 7 0,000 7,084E-03 0,02787842 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 7,084E-03 0,02784838 ! positive regulation of gene expression, epigenetic GO:0045815 7 7 0,000 7,084E-03 0,0278184 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 7 0,000 7,084E-03 0,02778849 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 7,084E-03 0,02775864 ! thymic T cell selection GO:0045061 16 7 0,000 7,084E-03 0,02772886 ! transepithelial chloride transport GO:0030321 7 7 0,000 7,084E-03 0,02769914 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 7,084E-03 0,02766948 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 7 7 0,000 7,084E-03 0,02763989 ! negative regulation of survival gene product expression GO:0008634 9 7 0,000 7,084E-03 0,02761036 ! melanocyte differentiation GO:0030318 8 7 0,000 7,084E-03 0,02758089 ! malate dehydrogenase activity GO:0016615 8 7 0,000 7,084E-03 0,02755149 ! mitochondrial respiratory chain complex assembly GO:0033108 7 7 0,000 7,084E-03 0,02752215 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! DNA secondary structure binding GO:0000217 16 7 0,000 7,084E-03 0,02749287 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 8 7 0,000 7,084E-03 0,02746365 ! regulation of peptidyl-serine phosphorylation GO:0033135 7 7 0,000 7,084E-03 0,0274345 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 7,084E-03 0,0274054 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 7,084E-03 0,02737637 GO:0021940|positive regulation of granule cell precursor proliferation, ! V(D)J recombination GO:0033151 8 7 0,000 7,084E-03 0,0273474 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 7,084E-03 0,02731849 ! vascular endothelial growth factor receptor activity GO:0005021 12 7 0,000 7,084E-03 0,02728965 ! central nervous system neuron axonogenesis GO:0021955 8 7 0,000 7,084E-03 0,02726086 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 7,084E-03 0,02723213 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! response to tumor necrosis factor GO:0034612 8 7 0,000 7,084E-03 0,02720347 ! peptidoglycan metabolic process GO:0000270 9 7 0,000 7,084E-03 0,02717486 GO:0009253|peptidoglycan catabolic process, ! response to ATP GO:0033198 7 7 0,000 7,084E-03 0,02714632 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 8 7 0,000 7,084E-03 0,02711783 GO:0048500|signal recognition particle, ! stereocilium GO:0032420 10 7 0,000 7,084E-03 0,02708941 ! paraxial mesoderm morphogenesis GO:0048340 9 7 0,000 7,084E-03 0,02706104 ! melanosome organization GO:0032438 7 7 0,000 7,084E-03 0,02703273 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 8 7 0,000 7,084E-03 0,02700449 ! mesodermal cell differentiation GO:0048333 9 7 0,000 7,084E-03 0,0269763 GO:0001710|mesodermal cell fate commitment, ! positive regulation of neuroblast proliferation GO:0002052 7 7 0,000 7,084E-03 0,02694817 ! Rac protein signal transduction GO:0016601 7 7 0,000 7,084E-03 0,0269201 ! chondrocyte differentiation GO:0002062 7 7 0,000 7,084E-03 0,02689209 ! guanylate cyclase regulator activity GO:0030249 7 7 0,000 7,084E-03 0,02686413 GO:0010851|cyclase regulator activity, ! intestinal cholesterol absorption GO:0030299 9 7 0,000 7,084E-03 0,02683624 ! negative regulation of specific transcription from RNA polymerase II promoter GO:0010553 8 7 0,000 7,084E-03 0,0268084 ! positive regulation of mitotic cell cycle GO:0045931 7 7 0,000 7,084E-03 0,02678062 ! determination of anterior/posterior axis, embryo GO:0008595 10 7 0,000 7,084E-03 0,02675289 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 8 7 0,000 7,084E-03 0,02672523 ! regulation of vascular endothelial growth factor production GO:0010574 7 7 0,000 7,084E-03 0,02669762 ! Schwann cell differentiation GO:0014037 8 7 0,000 7,084E-03 0,02667007 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 9 7 0,000 7,084E-03 0,02664257 ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 7,084E-03 0,02661513 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 7,084E-03 0,02658775 ! vinculin binding GO:0017166 9 7 0,000 7,084E-03 0,02656043 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 7,084E-03 0,02653316 ! regulation of collagen metabolic process GO:0010712 8 7 0,000 7,084E-03 0,02650594 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 7,084E-03 0,02647879 ! negative regulation of gliogenesis GO:0014014 8 7 0,000 7,084E-03 0,02645168 GO:0045686|negative regulation of glial cell differentiation, ! translation termination factor activity GO:0008079 7 7 0,000 7,084E-03 0,02642464 GO:0003747|translation release factor activity, ! purine base biosynthetic process GO:0009113 8 7 0,000 7,084E-03 0,02639765 ! cardiac muscle cell development GO:0055013 8 7 0,000 7,084E-03 0,02637071 ! fibrinolysis GO:0042730 9 7 0,000 7,084E-03 0,02634383 ! response to tropane GO:0014073 10 7 0,000 7,084E-03 0,026317 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 7 7 0,000 7,084E-03 0,02629023 GO:0051904|pigment granule transport, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 8 7 0,000 7,084E-03 0,02626351 ! glycosylceramide metabolic process GO:0006677 7 7 0,000 7,084E-03 0,02623685 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 7 7 0,000 7,084E-03 0,02621024 ! laminin-1 complex GO:0005606 7 7 0,000 7,084E-03 0,02618368 GO:0043256|laminin complex, ! regulation of chondrocyte differentiation GO:0032330 8 7 0,000 7,084E-03 0,02615718 ! positive regulation of immunoglobulin mediated immune response GO:0002891 7 7 0,000 7,084E-03 0,02613073 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of lipid transport GO:0032370 8 7 0,000 7,084E-03 0,02610434 ! regulation of cell division GO:0051302 7 7 0,000 7,084E-03 0,026078 ! holo TFIIH complex GO:0005675 7 7 0,000 7,084E-03 0,02605171 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 7 0,000 7,084E-03 0,02602547 ! chitinase activity GO:0004568 7 7 0,000 7,084E-03 0,02599929 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 8 7 0,000 7,084E-03 0,02597316 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! U12-type spliceosomal complex GO:0005689 8 7 0,000 7,084E-03 0,02594708 ! regulation of respiratory burst GO:0060263 8 7 0,000 7,084E-03 0,02592106 ! prophase GO:0051324 8 7 0,000 7,084E-03 0,02589508 ! peptidyl-histidine modification GO:0018202 8 7 0,000 7,084E-03 0,02586916 ! centriolar satellite GO:0034451 10 7 0,000 7,084E-03 0,02584329 ! BBSome GO:0034464 7 7 0,000 7,084E-03 0,02581748 ! glycerophosphodiester phosphodiesterase activity GO:0008889 7 7 0,000 7,084E-03 0,02579171 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 7,084E-03 0,025766 ! negative regulation of lymphocyte differentiation GO:0045620 8 7 0,000 7,084E-03 0,02574033 ! negative regulation of transmission of nerve impulse GO:0051970 7 7 0,000 7,084E-03 0,02571472 ! regulation of synaptic transmission, glutamatergic GO:0051966 8 7 0,000 7,084E-03 0,02568916 ! regulation of synaptogenesis GO:0051963 7 7 0,000 7,084E-03 0,02566365 ! serine family amino acid catabolic process GO:0009071 7 7 0,000 7,084E-03 0,02563819 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 7,084E-03 0,02561278 ! glycolipid catabolic process GO:0019377 7 7 0,000 7,084E-03 0,02558742 GO:0046479|glycosphingolipid catabolic process, ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 8 7 0,000 7,084E-03 0,02556211 ! circadian behavior GO:0048512 9 7 0,000 7,084E-03 0,02553685 ! dorsal/ventral axis specification GO:0009950 7 7 0,000 7,084E-03 0,02551164 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 7 0,000 7,084E-03 0,02548648 ! striatum development GO:0021756 7 7 0,000 7,084E-03 0,02546137 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 8 7 0,000 7,084E-03 0,02543631 ! triglyceride biosynthetic process GO:0019432 7 7 0,000 7,084E-03 0,0254113 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 7,084E-03 0,02538634 ! dystroglycan complex GO:0016011 9 7 0,000 7,084E-03 0,02536143 ! negative regulation of calcium ion transport GO:0051926 7 7 0,000 7,084E-03 0,02533656 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 7 0,000 7,084E-03 0,02531175 ! peroxiredoxin activity GO:0051920 7 7 0,000 7,084E-03 0,02528698 ! muscle adaptation GO:0043500 7 7 0,000 7,084E-03 0,02526226 ! regulation of muscle adaptation GO:0043502 7 7 0,000 7,084E-03 0,02523759 ! diacylglycerol metabolic process GO:0046339 7 7 0,000 7,084E-03 0,02521297 ! lysogeny GO:0030069 7 7 0,000 7,084E-03 0,0251884 GO:0019047|provirus integration, ! protein insertion into membrane GO:0051205 7 7 0,000 7,084E-03 0,02516387 ! sequestering of metal ion GO:0051238 9 7 0,000 7,084E-03 0,02513939 ! membrane attack complex GO:0005579 7 7 0,000 7,084E-03 0,02511496 ! fibrinogen complex GO:0005577 7 7 0,000 7,084E-03 0,02509058 ! metallo-sulfur cluster assembly GO:0031163 9 7 0,000 7,084E-03 0,02506624 GO:0016226|iron-sulfur cluster assembly, ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 7 0,000 7,084E-03 0,02504195 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 7 0,000 7,084E-03 0,02501771 ! GABA receptor binding GO:0050811 8 7 0,000 7,084E-03 0,02499351 ! sheet-forming collagen GO:0030935 7 7 0,000 7,084E-03 0,02496937 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 8 7 0,000 7,084E-03 0,02494526 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 8 7 0,000 7,084E-03 0,02492121 ! sphingomyelin phosphodiesterase activity GO:0004767 9 7 0,000 7,084E-03 0,0248972 ! regulation of epithelial cell differentiation GO:0030856 7 7 0,000 7,084E-03 0,02487324 ! 7S RNA binding GO:0008312 8 7 0,000 7,084E-03 0,02484932 ! positive regulation of lipid catabolic process GO:0050996 7 7 0,000 7,084E-03 0,02482545 ! protein phosphorylated amino acid binding GO:0045309 9 7 0,000 7,084E-03 0,02480163 ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 8 7 0,000 7,084E-03 0,02477785 ! regulation of long-term neuronal synaptic plasticity GO:0048169 17 7 0,000 7,084E-03 0,02475411 ! Golgi to endosome transport GO:0006895 8 7 0,000 7,084E-03 0,02473043 ! glucocorticoid receptor signaling pathway GO:0042921 7 7 0,000 7,084E-03 0,02470678 GO:0031958|corticosteroid receptor signaling pathway, ! succinate metabolic process GO:0006105 7 7 0,000 7,084E-03 0,02468318 ! fibril GO:0043205 7 7 0,000 7,084E-03 0,02465963 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 7,084E-03 0,02463612 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 7,084E-03 0,02461266 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 7 0,000 7,084E-03 0,02458924 ! sensory perception of bitter taste GO:0050913 7 7 0,000 7,084E-03 0,02456587 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 7,084E-03 0,02454254 ! posttranscriptional gene silencing by RNA GO:0035194 9 7 0,000 7,084E-03 0,02451925 GO:0016441|posttranscriptional gene silencing, ! cell division site part GO:0032155 9 7 0,000 7,084E-03 0,02449601 GO:0032153|cell division site, ! laminin binding GO:0043236 7 7 0,000 7,084E-03 0,02447282 ! equilibrioception GO:0050957 10 7 0,000 7,084E-03 0,02444966 ! G-protein coupled receptor kinase activity GO:0004703 9 7 0,000 7,084E-03 0,02442655 ! titin binding GO:0031432 7 7 0,000 7,084E-03 0,02440349 ! chemosensory behavior GO:0007635 9 7 0,000 7,084E-03 0,02438047 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 7,084E-03 0,02435749 GO:0032107|regulation of response to nutrient levels, ! plasma lipoprotein particle assembly GO:0034377 7 7 0,000 7,084E-03 0,02433455 ! cobalamin binding GO:0031419 7 7 0,000 7,084E-03 0,02431166 ! sodium:phosphate symporter activity GO:0005436 8 7 0,000 7,084E-03 0,02428881 ! response to axon injury GO:0048678 9 7 0,000 7,084E-03 0,024266 ! regulation of activin receptor signaling pathway GO:0032925 7 7 0,000 7,084E-03 0,02424324 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 7,084E-03 0,02422052 ! F-actin capping protein complex GO:0008290 8 7 0,000 7,084E-03 0,02419784 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 7,084E-03 0,02417521 ! cGMP-mediated signaling GO:0019934 8 7 0,000 7,084E-03 0,02415261 ! nerve growth factor receptor signaling pathway GO:0048011 8 7 0,000 7,084E-03 0,02413006 ! cAMP-dependent protein kinase activity GO:0004691 7 7 0,000 7,084E-03 0,02410755 ! senescence GO:0010149 8 7 0,000 7,084E-03 0,02408508 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 10 7 0,000 7,084E-03 0,02406266 ! nuclear localization sequence binding GO:0008139 8 7 0,000 7,084E-03 0,02404027 ! galactose metabolic process GO:0006012 8 7 0,000 7,084E-03 0,02401793 ! vesicle fusion GO:0006906 8 7 0,000 7,084E-03 0,02399563 ! maintenance of protein location in nucleus GO:0051457 7 7 0,000 7,084E-03 0,02397337 ! intracellular pH reduction GO:0051452 7 7 0,000 7,084E-03 0,02395115 ! glycerol ether catabolic process GO:0044269 16 7 0,000 7,084E-03 0,02392898 GO:0046461|neutral lipid catabolic process, GO:0046464|acylglycerol catabolic process, ! neurotransmitter catabolic process GO:0042135 9 7 0,000 7,084E-03 0,02390684 ! ruffle organization GO:0031529 9 7 0,000 7,084E-03 0,02388475 ! nucleoside transport GO:0015858 8 7 0,000 7,084E-03 0,02386269 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 7,084E-03 0,02384068 ! inclusion body GO:0016234 7 7 0,000 7,084E-03 0,0238187 ! Cajal body GO:0015030 7 7 0,000 7,084E-03 0,02379677 ! H4/H2A histone acetyltransferase complex GO:0043189 9 7 0,000 7,084E-03 0,02377488 ! rRNA modification GO:0000154 7 7 0,000 7,084E-03 0,02375303 ! PcG protein complex GO:0031519 7 7 0,000 7,084E-03 0,02373122 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 7,084E-03 0,02370944 ! NAD-dependent protein deacetylase activity GO:0034979 7 7 0,000 7,084E-03 0,02368771 GO:0017136|NAD-dependent histone deacetylase activity, ! spindle checkpoint GO:0031577 7 7 0,000 7,084E-03 0,02366602 ! apolipoprotein binding GO:0034185 9 7 0,000 7,084E-03 0,02364437 ! G1 DNA damage checkpoint GO:0031571 7 7 0,000 7,084E-03 0,02362276 ! segment specification GO:0007379 9 7 0,000 7,084E-03 0,02360118 ! pronucleus GO:0045120 25 7 0,000 7,084E-03 0,02357965 ! bile acid:sodium symporter activity GO:0008508 9 7 0,000 7,084E-03 0,02355815 ! Rac GTPase activator activity GO:0030675 9 7 0,000 7,084E-03 0,0235367 ! regulation of DNA repair GO:0006282 19 7 0,000 7,084E-03 0,02351528 ! preribosome GO:0030684 7 7 0,000 7,084E-03 0,0234939 ! DNA topological change GO:0006265 7 7 0,000 7,084E-03 0,02347257 ! DNA ligation GO:0006266 8 7 0,000 7,084E-03 0,02345127 ! hair follicle maturation GO:0048820 8 7 0,000 7,084E-03 0,02343 ! renal water homeostasis GO:0003091 7 7 0,000 7,084E-03 0,02340878 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 7,084E-03 0,0233876 ! positive regulation of interleukin-6 production GO:0032755 7 7 0,000 7,084E-03 0,02336645 ! interleukin-1 receptor activity GO:0004908 8 7 0,000 7,084E-03 0,02334534 ! positive regulation of tumor necrosis factor production GO:0032760 7 7 0,000 7,084E-03 0,02332427 ! positive regulation of monooxygenase activity GO:0032770 7 7 0,000 7,084E-03 0,02330324 ! inositol trisphosphate 3-kinase activity GO:0008440 8 7 0,000 7,084E-03 0,02328225 ! phosphofructokinase activity GO:0008443 7 7 0,000 7,084E-03 0,02326129 ! gap junction channel activity GO:0005243 8 7 0,000 7,084E-03 0,02324037 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 10 7 0,000 7,084E-03 0,02321949 ! histone methylation GO:0016571 7 7 0,000 7,084E-03 0,02319865 ! positive regulation of interferon-gamma production GO:0032729 7 7 0,000 7,084E-03 0,02317784 ! negative regulation of tumor necrosis factor production GO:0032720 9 7 0,000 7,084E-03 0,02315707 ! mitochondrion morphogenesis GO:0070584 9 7 0,000 7,084E-03 0,02313634 ! muscle cell proliferation GO:0033002 8 7 0,000 7,084E-03 0,02311565 ! transcription termination GO:0006353 9 7 0,000 7,084E-03 0,02309499 ! regulation of transcription from RNA polymerase III promoter GO:0006359 16 7 0,000 7,084E-03 0,02307437 ! sodium:amino acid symporter activity GO:0005283 7 7 0,000 7,084E-03 0,02305379 ! cytidylyltransferase activity GO:0070567 8 7 0,000 7,084E-03 0,02303324 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 7,084E-03 0,02301273 ! ATP-dependent peptidase activity GO:0004176 7 7 0,000 7,084E-03 0,02299225 ! salivary gland development GO:0007431 7 7 0,000 7,084E-03 0,02297182 ! glucosidase activity GO:0015926 8 7 0,000 7,084E-03 0,02295142 ! NuRD complex GO:0016581 8 7 0,000 7,084E-03 0,02293105 ! negative regulation of nuclear division GO:0051784 7 7 0,000 7,084E-03 0,02291072 GO:0045839|negative regulation of mitosis, ! ATP-gated cation channel activity GO:0004931 9 7 0,000 7,084E-03 0,02289043 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 7 7 0,000 7,084E-03 0,02287017 ! response to redox state GO:0051775 8 7 0,000 7,084E-03 0,02284995 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 7,084E-03 0,02282977 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 7,084E-03 0,02280962 ! procollagen-proline dioxygenase activity GO:0019798 7 7 0,000 7,084E-03 0,0227895 ! actin monomer binding GO:0003785 7 7 0,000 7,084E-03 0,02276942 ! protein prenyltransferase activity GO:0008318 8 7 0,000 7,084E-03 0,02274938 ! endosome to lysosome transport GO:0008333 7 7 0,000 7,084E-03 0,02272937 ! regulation of Rac protein signal transduction GO:0035020 17 7 0,000 7,084E-03 0,0227094 ! germ cell migration GO:0008354 7 7 0,000 7,084E-03 0,02268946 ! fibroblast growth factor receptor binding GO:0005104 8 7 0,000 7,084E-03 0,02266956 ! negative regulation of organic acid transport GO:0032891 8 7 0,000 7,084E-03 0,02264969 ! CoA-ligase activity GO:0016405 8 7 0,000 7,084E-03 0,02262986 ! positive regulation of NF-kappaB import into nucleus GO:0042346 8 7 0,000 7,084E-03 0,02261006 ! interferon-alpha/beta receptor binding GO:0005132 7 7 0,000 7,084E-03 0,02259029 ! embryonic heart tube development GO:0035050 8 7 0,000 7,084E-03 0,02257056 ! dihydropyridine-sensitive calcium channel activity GO:0015270 10 7 0,000 7,084E-03 0,02255087 ! kainate selective glutamate receptor activity GO:0015277 8 7 0,000 7,084E-03 0,02253121 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 7,084E-03 0,02251158 ! amiloride-sensitive sodium channel activity GO:0015280 7 7 0,000 7,084E-03 0,02249199 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 7,084E-03 0,02247243 ! adenylate kinase activity GO:0004017 8 7 0,000 7,084E-03 0,02245291 ! negative regulation of immune effector process GO:0002698 13 7 0,000 7,084E-03 0,02243342 ! C-X-C chemokine receptor activity GO:0016494 7 7 0,000 7,084E-03 0,02241396 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 7 7 0,000 7,084E-03 0,02239454 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 10 8 0,000 8,092E-03 0,02555931 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 9 8 0,000 8,092E-03 0,0255372 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 8 0,000 8,092E-03 0,02551513 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 8,092E-03 0,02549309 ! negative regulation of lipid biosynthetic process GO:0051055 18 8 0,000 8,092E-03 0,0254711 ! regulation of cellular amine metabolic process GO:0033238 10 8 0,000 8,092E-03 0,02544914 ! proteasome regulatory particle GO:0005838 8 8 0,000 8,092E-03 0,02542722 ! SMAD protein complex assembly GO:0007183 10 8 0,000 8,092E-03 0,02540534 ! regulation of smooth muscle cell migration GO:0014910 11 8 0,000 8,092E-03 0,02538349 ! protein self-association GO:0043621 8 8 0,000 8,092E-03 0,02536169 ! glycine hydroxymethyltransferase activity GO:0004372 9 8 0,000 8,092E-03 0,02533992 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 8 0,000 8,092E-03 0,02531819 ! neurotransmitter uptake GO:0001504 8 8 0,000 8,092E-03 0,02529649 ! regulation of activated T cell proliferation GO:0046006 9 8 0,000 8,092E-03 0,02527483 ! guanylate cyclase activity GO:0004383 9 8 0,000 8,092E-03 0,02525321 ! troponin complex GO:0005861 8 8 0,000 8,092E-03 0,02523163 ! eukaryotic translation initiation factor 3 complex GO:0005852 8 8 0,000 8,092E-03 0,02521008 ! tachykinin receptor signaling pathway GO:0007217 8 8 0,000 8,092E-03 0,02518857 ! negative regulation of muscle cell differentiation GO:0051148 10 8 0,000 8,092E-03 0,0251671 ! microtubule bundle formation GO:0001578 8 8 0,000 8,092E-03 0,02514566 ! middle ear morphogenesis GO:0042474 10 8 0,000 8,092E-03 0,02512426 ! ganglioside metabolic process GO:0001573 8 8 0,000 8,092E-03 0,02510289 ! regulation of mesenchymal cell proliferation GO:0010464 9 8 0,000 8,092E-03 0,02508157 GO:0002053|positive regulation of mesenchymal cell proliferation, ! ovulation from ovarian follicle GO:0001542 8 8 0,000 8,092E-03 0,02506028 ! ciliary or flagellar motility GO:0001539 8 8 0,000 8,092E-03 0,02503902 ! pathogenesis GO:0009405 8 8 0,000 8,092E-03 0,0250178 ! pH reduction GO:0045851 9 8 0,000 8,092E-03 0,02499662 ! small protein activating enzyme activity GO:0008641 10 8 0,000 8,092E-03 0,02497547 ! ribonucleoside triphosphate catabolic process GO:0009203 8 8 0,000 8,092E-03 0,02495436 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 8,092E-03 0,02493328 ! hemoglobin metabolic process GO:0020027 8 8 0,000 8,092E-03 0,02491224 ! arginine catabolic process GO:0006527 9 8 0,000 8,092E-03 0,02489123 ! T-tubule GO:0030315 9 8 0,000 8,092E-03 0,02487026 ! regulation of defense response to virus by virus GO:0050690 17 8 0,000 8,092E-03 0,02484933 ! histidine catabolic process GO:0006548 8 8 0,000 8,092E-03 0,02482843 GO:0009077|histidine family amino acid catabolic process, ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 8,092E-03 0,02480757 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 8 0,000 8,092E-03 0,02478674 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 10 8 0,000 8,092E-03 0,02476594 ! proline metabolic process GO:0006560 10 8 0,000 8,092E-03 0,02474518 ! L-serine metabolic process GO:0006563 9 8 0,000 8,092E-03 0,02472446 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 8 8 0,000 8,092E-03 0,02470377 ! melanosome membrane GO:0033162 9 8 0,000 8,092E-03 0,02468311 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 8,092E-03 0,02466249 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 8 8 0,000 8,092E-03 0,02464191 ! pericentriolar material GO:0000242 9 8 0,000 8,092E-03 0,02462135 ! reverse cholesterol transport GO:0043691 8 8 0,000 8,092E-03 0,02460084 ! tumor necrosis factor receptor activity GO:0005031 8 8 0,000 8,092E-03 0,02458035 ! melanin metabolic process GO:0006582 10 8 0,000 8,092E-03 0,0245599 ! proton-transporting V-type ATPase, V1 domain GO:0033180 8 8 0,000 8,092E-03 0,02453949 ! phasic smooth muscle contraction GO:0014821 9 8 0,000 8,092E-03 0,02451911 ! Golgi lumen GO:0005796 8 8 0,000 8,092E-03 0,02449876 ! positive regulation of endothelial cell migration GO:0010595 9 8 0,000 8,092E-03 0,02447844 ! regulation of Cdc42 protein signal transduction GO:0032489 9 8 0,000 8,092E-03 0,02445816 GO:0043088|regulation of Cdc42 GTPase activity, ! methyltransferase complex GO:0034708 8 8 0,000 8,092E-03 0,02443792 GO:0035097|histone methyltransferase complex, ! paraxial mesoderm development GO:0048339 10 8 0,000 8,092E-03 0,0244177 ! stereocilium bundle GO:0032421 11 8 0,000 8,092E-03 0,02439752 ! forebrain cell migration GO:0021885 9 8 0,000 8,092E-03 0,02437738 ! peptidyl-threonine phosphorylation GO:0018107 11 8 0,000 8,092E-03 0,02435726 ! osteoblast development GO:0002076 11 8 0,000 8,092E-03 0,02433718 ! retinoic acid metabolic process GO:0042573 8 8 0,000 8,092E-03 0,02431714 ! retinol metabolic process GO:0042572 8 8 0,000 8,092E-03 0,02429712 ! negative regulation of muscle contraction GO:0045932 10 8 0,000 8,092E-03 0,02427714 ! structural constituent of epidermis GO:0030280 9 8 0,000 8,092E-03 0,02425719 ! clathrin binding GO:0030276 10 8 0,000 8,092E-03 0,02423728 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 9 8 0,000 8,092E-03 0,02421739 ! chondroitin sulfate biosynthetic process GO:0030206 9 8 0,000 8,092E-03 0,02419754 GO:0030204|chondroitin sulfate metabolic process, ! sodium:dicarboxylate symporter activity GO:0017153 9 8 0,000 8,092E-03 0,02417773 ! motor axon guidance GO:0008045 8 8 0,000 8,092E-03 0,02415794 ! protein targeting to vacuole GO:0006623 8 8 0,000 8,092E-03 0,02413819 ! negative regulation of axonogenesis GO:0050771 12 8 0,000 8,092E-03 0,02411847 ! peptidyl-asparagine modification GO:0018196 8 8 0,000 8,092E-03 0,02409878 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! melanosome localization GO:0032400 8 8 0,000 8,092E-03 0,02407912 GO:0032401|establishment of melanosome localization, GO:0051875|pigment granule localization, GO:0051905|establishment of pigment granule localization, ! mismatch repair complex binding GO:0032404 10 8 0,000 8,092E-03 0,0240595 ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 8,092E-03 0,02403991 ! protein-lipid complex assembly GO:0065005 8 8 0,000 8,092E-03 0,02402034 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 9 8 0,000 8,092E-03 0,02400082 ! phosphoinositide 3-kinase cascade GO:0014065 8 8 0,000 8,092E-03 0,02398132 ! regulation of dopamine secretion GO:0014059 9 8 0,000 8,092E-03 0,02396185 ! regulation of protein kinase B signaling cascade GO:0051896 9 8 0,000 8,092E-03 0,02394242 ! cranial nerve morphogenesis GO:0021602 9 8 0,000 8,092E-03 0,02392302 ! subpallium development GO:0021544 8 8 0,000 8,092E-03 0,02390365 ! icosanoid secretion GO:0032309 10 8 0,000 8,092E-03 0,02388431 GO:0050482|arachidonic acid secretion, ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 8,092E-03 0,023865 ! regulation of DNA replication initiation GO:0030174 8 8 0,000 8,092E-03 0,02384572 ! negative regulation of cytokine secretion GO:0050710 10 8 0,000 8,092E-03 0,02382648 ! dolichyl-diphosphooligosaccharide-protein glycotransferase activity GO:0004579 8 8 0,000 8,092E-03 0,02380726 ! exodeoxyribonuclease activity GO:0004529 18 8 0,000 8,092E-03 0,02378808 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! ER to Golgi transport vesicle GO:0030134 9 8 0,000 8,092E-03 0,02376892 ! nucleotide diphosphatase activity GO:0004551 9 8 0,000 8,092E-03 0,0237498 ! regulation of myoblast differentiation GO:0045661 9 8 0,000 8,092E-03 0,02373071 ! ubiquinone metabolic process GO:0006743 9 8 0,000 8,092E-03 0,02371165 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! neuromuscular process controlling posture GO:0050884 8 8 0,000 8,092E-03 0,02369262 ! multicellular organismal water homeostasis GO:0050891 8 8 0,000 8,092E-03 0,02367362 ! branched chain family amino acid catabolic process GO:0009083 9 8 0,000 8,092E-03 0,02365465 ! Wnt receptor activity GO:0042813 11 8 0,000 8,092E-03 0,02363571 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 8,092E-03 0,0236168 ! leukocyte mediated cytotoxicity GO:0001909 10 8 0,000 8,092E-03 0,02359792 ! detection of calcium ion GO:0005513 9 8 0,000 8,092E-03 0,02357908 ! negative regulation of glucose import GO:0046325 9 8 0,000 8,092E-03 0,02356026 ! blastocyst growth GO:0001832 8 8 0,000 8,092E-03 0,02354147 ! regulation of fibrinolysis GO:0051917 8 8 0,000 8,092E-03 0,02352271 ! negative regulation of telomere maintenance GO:0032205 9 8 0,000 8,092E-03 0,02350398 ! complement binding GO:0001848 11 8 0,000 8,092E-03 0,02348529 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 8 0,000 8,092E-03 0,02346662 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 8 0,000 8,092E-03 0,02344798 ! amino sugar catabolic process GO:0046348 8 8 0,000 8,092E-03 0,02342937 GO:0006043|glucosamine catabolic process, ! FK506 binding GO:0005528 9 8 0,000 8,092E-03 0,02341079 GO:0005527|macrolide binding, ! dipeptidase activity GO:0016805 8 8 0,000 8,092E-03 0,02339224 ! positive regulation of amine transport GO:0051954 9 8 0,000 8,092E-03 0,02337372 ! release of sequestered calcium ion into cytosol GO:0051209 13 8 0,000 8,092E-03 0,02335522 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, ! B cell receptor signaling pathway GO:0050853 13 8 0,000 8,092E-03 0,02333676 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 8,092E-03 0,02331833 ! Golgi transport complex GO:0017119 8 8 0,000 8,092E-03 0,02329992 ! positive regulation of protein ubiquitination GO:0031398 17 8 0,000 8,092E-03 0,02328155 ! GDP binding GO:0019003 9 8 0,000 8,092E-03 0,0232632 ! positive regulation of glucose metabolic process GO:0010907 8 8 0,000 8,092E-03 0,02324489 ! prostate gland development GO:0030850 17 8 0,000 8,092E-03 0,0232266 ! DNA synthesis during DNA repair GO:0000731 19 8 0,000 8,092E-03 0,02320834 ! nitric-oxide synthase binding GO:0050998 9 8 0,000 8,092E-03 0,02319011 ! phosphate transport GO:0006817 9 8 0,000 8,092E-03 0,0231719 ! cellular copper ion homeostasis GO:0006878 8 8 0,000 8,092E-03 0,02315373 ! oligopeptide transport GO:0006857 8 8 0,000 8,092E-03 0,02313558 GO:0015198|oligopeptide transporter activity, ! pigment cell differentiation GO:0050931 9 8 0,000 8,092E-03 0,02311747 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 8,092E-03 0,02309938 ! oligosaccharyltransferase complex GO:0008250 8 8 0,000 8,092E-03 0,02308132 ! lipoprotein transport GO:0042953 9 8 0,000 8,092E-03 0,02306328 ! estrogen metabolic process GO:0008210 8 8 0,000 8,092E-03 0,02304528 ! nucleocytoplasmic transporter activity GO:0005487 8 8 0,000 8,092E-03 0,0230273 ! glucocorticoid metabolic process GO:0008211 8 8 0,000 8,092E-03 0,02300936 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 8 8 0,000 8,092E-03 0,02299144 ! T-helper 1 type immune response GO:0042088 8 8 0,000 8,092E-03 0,02297354 ! amyloid precursor protein catabolic process GO:0042987 10 8 0,000 8,092E-03 0,02295568 ! response to amphetamine GO:0001975 11 8 0,000 8,092E-03 0,02293784 ! mechanosensory behavior GO:0007638 8 8 0,000 8,092E-03 0,02292003 ! detection of chemical stimulus involved in sensory perception GO:0050907 8 8 0,000 8,092E-03 0,02290225 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 8,092E-03 0,0228845 ! C-X-C chemokine binding GO:0019958 8 8 0,000 8,092E-03 0,02286677 ! two-component signal transduction system (phosphorelay) GO:0000160 9 8 0,000 8,092E-03 0,02284907 ! glycerolipid catabolic process GO:0046503 17 8 0,000 8,092E-03 0,0228314 ! spinal cord dorsal/ventral patterning GO:0021513 10 8 0,000 8,092E-03 0,02281376 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 9 8 0,000 8,092E-03 0,02279614 ! inositol phosphate-mediated signaling GO:0048016 9 8 0,000 8,092E-03 0,02277855 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 8,092E-03 0,02276099 ! pigment granule organization GO:0048753 9 8 0,000 8,092E-03 0,02274345 ! GTP-dependent protein binding GO:0030742 11 8 0,000 8,092E-03 0,02272595 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 8,092E-03 0,02270846 ! regulation of interleukin-8 biosynthetic process GO:0045414 9 8 0,000 8,092E-03 0,02269101 ! regulation of pigmentation during development GO:0048070 11 8 0,000 8,092E-03 0,02267358 ! macrophage activation GO:0042116 8 8 0,000 8,092E-03 0,02265618 ! poly(A) RNA binding GO:0008143 8 8 0,000 8,092E-03 0,02263881 ! positive regulation of insulin secretion GO:0032024 10 8 0,000 8,092E-03 0,02262146 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 18 8 0,000 8,092E-03 0,02260414 ! asymmetric protein localization GO:0008105 9 8 0,000 8,092E-03 0,02258684 ! nucleotide-sugar transmembrane transporter activity GO:0005338 8 8 0,000 8,092E-03 0,02256957 ! neurotrophin binding GO:0043121 10 8 0,000 8,092E-03 0,02255233 ! nucleoside transmembrane transporter activity GO:0005337 9 8 0,000 8,092E-03 0,02253512 ! positive regulation of multicellular organismal metabolic process GO:0044253 9 8 0,000 8,092E-03 0,02251793 ! phagocytosis, engulfment GO:0006911 10 8 0,000 8,092E-03 0,02250077 ! UDP-glucosyltransferase activity GO:0035251 8 8 0,000 8,092E-03 0,02248363 ! neurotransmitter biosynthetic process GO:0042136 9 8 0,000 8,092E-03 0,02246652 ! UV protection GO:0009650 9 8 0,000 8,092E-03 0,02244943 ! peptidyl-proline dioxygenase activity GO:0031543 8 8 0,000 8,092E-03 0,02243237 ! eukaryotic translation initiation factor 4F complex GO:0016281 10 8 0,000 8,092E-03 0,02241534 ! glutathione peroxidase activity GO:0004602 17 8 0,000 8,092E-03 0,02239833 ! acyl-CoA thioesterase activity GO:0016291 10 8 0,000 8,092E-03 0,02238135 ! ATP-binding cassette (ABC) transporter complex GO:0043190 8 8 0,000 8,092E-03 0,0223644 ! ferric iron binding GO:0008199 9 8 0,000 8,092E-03 0,02234747 ! response to UV-B GO:0010224 10 8 0,000 8,092E-03 0,02233056 ! intermediate filament organization GO:0045109 8 8 0,000 8,092E-03 0,02231368 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 8,092E-03 0,02229683 ! cellular extravasation GO:0045123 9 8 0,000 8,092E-03 0,02228 ! skeletal muscle contraction GO:0003009 8 8 0,000 8,092E-03 0,0222632 ! positive regulation of cytokine production during immune response GO:0002720 8 8 0,000 8,092E-03 0,02224642 ! regulation of fatty acid biosynthetic process GO:0042304 17 8 0,000 8,092E-03 0,02222967 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 8,092E-03 0,02221295 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 8,092E-03 0,02219624 ! positive regulation of systemic arterial blood pressure GO:0003084 10 8 0,000 8,092E-03 0,02217957 ! negative regulation of systemic arterial blood pressure GO:0003085 9 8 0,000 8,092E-03 0,02216292 ! respiratory chain complex IV assembly GO:0008535 8 8 0,000 8,092E-03 0,02214629 ! erythrocyte development GO:0048821 9 8 0,000 8,092E-03 0,02212969 ! regulation of interleukin-10 production GO:0032653 8 8 0,000 8,092E-03 0,02211311 ! ribosome assembly GO:0042255 8 8 0,000 8,092E-03 0,02209656 ! postreplication repair GO:0006301 19 8 0,000 8,092E-03 0,02208003 ! gamma-tubulin binding GO:0043015 8 8 0,000 8,092E-03 0,02206353 ! NADPH oxidase complex GO:0043020 8 8 0,000 8,092E-03 0,02204705 ! mRNA cleavage GO:0006379 9 8 0,000 8,092E-03 0,0220306 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 9 8 0,000 8,092E-03 0,02201417 ! opioid receptor activity GO:0004985 8 8 0,000 8,092E-03 0,02199777 ! zymogen activation GO:0031638 9 8 0,000 8,092E-03 0,02198139 ! coenzyme A metabolic process GO:0015936 8 8 0,000 8,092E-03 0,02196503 ! cellular metabolic compound salvage GO:0043094 11 8 0,000 8,092E-03 0,0219487 ! costamere GO:0043034 8 8 0,000 8,092E-03 0,0219324 ! inositol trisphosphate kinase activity GO:0051766 9 8 0,000 8,092E-03 0,02191611 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 8,092E-03 0,02189985 ! sarcomere organization GO:0045214 9 8 0,000 8,092E-03 0,02188362 ! wide pore channel activity GO:0022829 9 8 0,000 8,092E-03 0,02186741 ! ligand-regulated transcription factor activity GO:0003706 10 8 0,000 8,092E-03 0,02185122 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 8,092E-03 0,02183506 ! hormone catabolic process GO:0042447 9 8 0,000 8,092E-03 0,02181892 ! mRNA 3'-UTR binding GO:0003730 9 8 0,000 8,092E-03 0,02180281 ! cGMP biosynthetic process GO:0006182 9 8 0,000 8,092E-03 0,02178672 ! lysozyme activity GO:0003796 10 8 0,000 8,092E-03 0,02177065 ! death receptor binding GO:0005123 8 8 0,000 8,092E-03 0,02175461 ! protein modification by small protein removal GO:0070646 9 8 0,000 8,092E-03 0,02173859 ! adult feeding behavior GO:0008343 9 8 0,000 8,092E-03 0,02172259 ! microtubule basal body GO:0005932 8 8 0,000 8,092E-03 0,02170662 ! pyrimidine nucleotide catabolic process GO:0006244 8 8 0,000 8,092E-03 0,02169067 ! interleukin-1 receptor binding GO:0005149 9 8 0,000 8,092E-03 0,02167475 ! calcium-release channel activity GO:0015278 8 8 0,000 8,092E-03 0,02165884 ! positive regulation of smooth muscle contraction GO:0045987 9 8 0,000 8,092E-03 0,02164296 ! behavioral response to nicotine GO:0035095 9 8 0,000 8,092E-03 0,02162711 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 8,092E-03 0,02161128 ! NAD biosynthetic process GO:0009435 9 8 0,000 8,092E-03 0,02159547 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 9 0,000 9,1E-03 0,02426548 ! positive regulation of glycogen biosynthetic process GO:0045725 9 9 0,000 9,1E-03 0,02424775 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 9,1E-03 0,02423006 ! sodium:hydrogen antiporter activity GO:0015385 9 9 0,000 9,1E-03 0,02421238 GO:0005451|monovalent cation:hydrogen antiporter activity, ! cGMP metabolic process GO:0046068 10 9 0,000 9,1E-03 0,02419473 ! myotube differentiation GO:0014902 9 9 0,000 9,1E-03 0,02417711 ! folic acid and derivative biosynthetic process GO:0009396 9 9 0,000 9,1E-03 0,02415952 ! N-glycan processing GO:0006491 10 9 0,000 9,1E-03 0,02414195 ! regulation of epidermal growth factor receptor activity GO:0007176 11 9 0,000 9,1E-03 0,0241244 ! actin-myosin filament sliding GO:0033275 11 9 0,000 9,1E-03 0,02410688 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! axon part GO:0033267 12 9 0,000 9,1E-03 0,02408939 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 10 9 0,000 9,1E-03 0,02407192 ! RNA methylation GO:0001510 9 9 0,000 9,1E-03 0,02405448 ! prostaglandin biosynthetic process GO:0001516 9 9 0,000 9,1E-03 0,02403706 GO:0046457|prostanoid biosynthetic process, ! negative regulation of gene-specific transcription GO:0032582 10 9 0,000 9,1E-03 0,02401966 ! artery development GO:0060840 9 9 0,000 9,1E-03 0,0240023 GO:0048844|artery morphogenesis, ! axonemal dynein complex GO:0005858 9 9 0,000 9,1E-03 0,02398495 ! regulation of postsynaptic membrane potential GO:0060078 11 9 0,000 9,1E-03 0,02396764 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 9 9 0,000 9,1E-03 0,02395034 ! auditory receptor cell differentiation GO:0042491 10 9 0,000 9,1E-03 0,02393308 ! positive regulation of heart contraction GO:0045823 11 9 0,000 9,1E-03 0,02391583 ! lipopolysaccharide binding GO:0001530 9 9 0,000 9,1E-03 0,02389861 ! regulated secretory pathway GO:0045055 10 9 0,000 9,1E-03 0,02388142 ! estrogen receptor binding GO:0030331 9 9 0,000 9,1E-03 0,02386425 ! inner mitochondrial membrane organization GO:0007007 10 9 0,000 9,1E-03 0,02384711 ! telomere maintenance via telomerase GO:0007004 20 9 0,000 9,1E-03 0,02382999 GO:0006278|RNA-dependent DNA replication, ! L-phenylalanine metabolic process GO:0006558 9 9 0,000 9,1E-03 0,0238129 GO:0006559|L-phenylalanine catabolic process, ! indolalkylamine metabolic process GO:0006586 9 9 0,000 9,1E-03 0,02379582 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! urea metabolic process GO:0019627 19 9 0,000 9,1E-03 0,02377878 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! smooth endoplasmic reticulum GO:0005790 11 9 0,000 9,1E-03 0,02376176 ! autophagic vacuole GO:0005776 11 9 0,000 9,1E-03 0,02374476 ! Rac GTPase binding GO:0048365 10 9 0,000 9,1E-03 0,02372779 ! response to dietary excess GO:0002021 9 9 0,000 9,1E-03 0,02371084 ! regulation of sodium ion transport GO:0002028 10 9 0,000 9,1E-03 0,02369392 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 9,1E-03 0,02367702 ! lens development in camera-type eye GO:0002088 9 9 0,000 9,1E-03 0,02366014 ! male sex determination GO:0030238 9 9 0,000 9,1E-03 0,02364329 ! positive regulation of vasodilation GO:0045909 19 9 0,000 9,1E-03 0,02362646 ! positive regulation of muscle contraction GO:0045933 11 9 0,000 9,1E-03 0,02360966 ! regulation of smoothened signaling pathway GO:0008589 11 9 0,000 9,1E-03 0,02359288 ! male germ cell nucleus GO:0001673 11 9 0,000 9,1E-03 0,02357612 ! negative regulation of foam cell differentiation GO:0010745 12 9 0,000 9,1E-03 0,02355939 ! copper ion homeostasis GO:0055070 9 9 0,000 9,1E-03 0,02354268 ! protein heterooligomerization GO:0051291 10 9 0,000 9,1E-03 0,02352599 ! spectrin GO:0008091 9 9 0,000 9,1E-03 0,02350933 ! cardiac muscle cell differentiation GO:0055007 12 9 0,000 9,1E-03 0,02349269 ! purine nucleoside triphosphate catabolic process GO:0009146 9 9 0,000 9,1E-03 0,02347608 ! synaptic vesicle exocytosis GO:0016079 10 9 0,000 9,1E-03 0,02345949 ! regulation of B cell differentiation GO:0045577 10 9 0,000 9,1E-03 0,02344292 ! neural tube patterning GO:0021532 10 9 0,000 9,1E-03 0,02342638 ! fucose catabolic process GO:0019317 10 9 0,000 9,1E-03 0,02340986 GO:0042355|L-fucose catabolic process, ! retinal ganglion cell axon guidance GO:0031290 10 9 0,000 9,1E-03 0,02339336 ! regulation of hormone metabolic process GO:0032350 12 9 0,000 9,1E-03 0,02337688 ! sterol catabolic process GO:0016127 10 9 0,000 9,1E-03 0,02336043 GO:0006707|cholesterol catabolic process, ! oligosaccharyl transferase activity GO:0004576 9 9 0,000 9,1E-03 0,02334401 ! clathrin coat of coated pit GO:0030132 11 9 0,000 9,1E-03 0,0233276 ! SNARE complex GO:0031201 11 9 0,000 9,1E-03 0,02331122 ! negative regulation of osteoclast differentiation GO:0045671 10 9 0,000 9,1E-03 0,02329486 ! negative regulation of glucose transport GO:0010829 10 9 0,000 9,1E-03 0,02327852 ! methionine biosynthetic process GO:0009086 11 9 0,000 9,1E-03 0,02326221 ! peptidoglycan binding GO:0042834 9 9 0,000 9,1E-03 0,02324592 ! serine family amino acid biosynthetic process GO:0009070 10 9 0,000 9,1E-03 0,02322965 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 9,1E-03 0,02321341 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! nicotinamide nucleotide biosynthetic process GO:0019359 10 9 0,000 9,1E-03 0,02319719 ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 9 9 0,000 9,1E-03 0,02318099 GO:0003756|protein disulfide isomerase activity, ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 9,1E-03 0,02316481 ! beta-1,3-galactosyltransferase activity GO:0048531 10 9 0,000 9,1E-03 0,02314866 ! detection of bacterium GO:0016045 10 9 0,000 9,1E-03 0,02313253 ! lymphocyte activation during immune response GO:0002285 9 9 0,000 9,1E-03 0,02311642 ! embryonic gut development GO:0048566 10 9 0,000 9,1E-03 0,02310033 ! hydrolase activity, acting on ether bonds GO:0016801 10 9 0,000 9,1E-03 0,02308427 ! desmosome GO:0030057 10 9 0,000 9,1E-03 0,02306822 ! long-chain-fatty-acid-CoA ligase activity GO:0004467 9 9 0,000 9,1E-03 0,02305221 ! T cell receptor signaling pathway GO:0050852 14 9 0,000 9,1E-03 0,02303621 ! positive regulation of calcium-mediated signaling GO:0050850 11 9 0,000 9,1E-03 0,02302023 ! actin filament polymerization GO:0030041 10 9 0,000 9,1E-03 0,02300428 ! negative regulation of B cell activation GO:0050869 10 9 0,000 9,1E-03 0,02298835 ! establishment of cell polarity GO:0030010 10 9 0,000 9,1E-03 0,02297244 ! regulation of synapse organization GO:0050807 10 9 0,000 9,1E-03 0,02295655 ! septin complex GO:0031105 10 9 0,000 9,1E-03 0,02294069 GO:0032156|septin cytoskeleton, ! cholesterol transporter activity GO:0017127 9 9 0,000 9,1E-03 0,02292485 ! anchoring collagen GO:0030934 9 9 0,000 9,1E-03 0,02290902 ! defense response to Gram-negative bacterium GO:0050829 10 9 0,000 9,1E-03 0,02289322 ! regulation of developmental growth GO:0048638 11 9 0,000 9,1E-03 0,02287745 ! negative regulation of smooth muscle cell proliferation GO:0048662 10 9 0,000 9,1E-03 0,02286169 ! GMP binding GO:0019002 11 9 0,000 9,1E-03 0,02284596 GO:0030553|cGMP binding, ! photoreceptor activity GO:0009881 10 9 0,000 9,1E-03 0,02283024 ! virus-host interaction GO:0019048 13 9 0,000 9,1E-03 0,02281455 ! pentose-phosphate shunt GO:0006098 11 9 0,000 9,1E-03 0,02279888 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 9,1E-03 0,02278324 ! negative regulation of lipid catabolic process GO:0050995 11 9 0,000 9,1E-03 0,02276761 ! non-recombinational repair GO:0000726 10 9 0,000 9,1E-03 0,02275201 GO:0006303|double-strand break repair via nonhomologous end joining, ! cell volume homeostasis GO:0006884 10 9 0,000 9,1E-03 0,02273642 ! nuclear telomere cap complex GO:0000783 10 9 0,000 9,1E-03 0,02272086 GO:0000782|telomere cap complex, ! activin binding GO:0048185 10 9 0,000 9,1E-03 0,02270532 ! social behavior GO:0035176 10 9 0,000 9,1E-03 0,0226898 ! regulation of positive chemotaxis GO:0050926 11 9 0,000 9,1E-03 0,0226743 GO:0050927|positive regulation of positive chemotaxis, ! perikaryon GO:0043204 11 9 0,000 9,1E-03 0,02265882 ! nitric oxide biosynthetic process GO:0006809 10 9 0,000 9,1E-03 0,02264337 ! mating GO:0007618 11 9 0,000 9,1E-03 0,02262793 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 9 0,000 9,1E-03 0,02261252 ! rhythmic behavior GO:0007622 11 9 0,000 9,1E-03 0,02259712 ! phospholipid efflux GO:0033700 10 9 0,000 9,1E-03 0,02258175 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 9,1E-03 0,0225664 ! poly-purine tract binding GO:0070717 9 9 0,000 9,1E-03 0,02255107 ! T cell proliferation GO:0042098 10 9 0,000 9,1E-03 0,02253576 ! retinol dehydrogenase activity GO:0004745 9 9 0,000 9,1E-03 0,02252047 ! negative regulation of cell-matrix adhesion GO:0001953 10 9 0,000 9,1E-03 0,0225052 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 9 9 0,000 9,1E-03 0,02248996 ! interleukin-1 binding GO:0019966 10 9 0,000 9,1E-03 0,02247473 ! glucosyltransferase activity GO:0046527 9 9 0,000 9,1E-03 0,02245952 ! platelet-derived growth factor receptor signaling pathway GO:0048008 14 9 0,000 9,1E-03 0,02244434 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 11 9 0,000 9,1E-03 0,02242917 ! ovulation GO:0030728 9 9 0,000 9,1E-03 0,02241403 ! acid phosphatase activity GO:0003993 18 9 0,000 9,1E-03 0,0223989 ! embryonic cranial skeleton morphogenesis GO:0048701 10 9 0,000 9,1E-03 0,0223838 ! ER overload response GO:0006983 11 9 0,000 9,1E-03 0,02236872 ! B cell proliferation GO:0042100 10 9 0,000 9,1E-03 0,02235365 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 11 9 0,000 9,1E-03 0,02233861 ! calcium-transporting ATPase activity GO:0005388 11 9 0,000 9,1E-03 0,02232359 ! mannose metabolic process GO:0006013 13 9 0,000 9,1E-03 0,02230859 ! lipid digestion GO:0044241 11 9 0,000 9,1E-03 0,0222936 ! tumor necrosis factor binding GO:0043120 9 9 0,000 9,1E-03 0,02227864 ! tRNA methyltransferase activity GO:0008175 9 9 0,000 9,1E-03 0,0222637 ! regulation of bone resorption GO:0045124 10 9 0,000 9,1E-03 0,02224878 ! brain morphogenesis GO:0048854 9 9 0,000 9,1E-03 0,02223388 ! positive regulation of alpha-beta T cell differentiation GO:0046638 10 9 0,000 9,1E-03 0,02221899 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 10 9 0,000 9,1E-03 0,02220413 ! synaptic vesicle membrane GO:0030672 9 9 0,000 9,1E-03 0,02218929 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 9 0,000 9,1E-03 0,02217447 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9 9 0,000 9,1E-03 0,02215966 ! kinesin binding GO:0019894 9 9 0,000 9,1E-03 0,02214488 ! multicellular organismal aging GO:0010259 18 9 0,000 9,1E-03 0,02213012 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 9,1E-03 0,02211537 ! protein import into peroxisome matrix GO:0016558 9 9 0,000 9,1E-03 0,02210065 ! mRNA polyadenylation GO:0006378 10 9 0,000 9,1E-03 0,02208595 ! neuropeptide Y receptor activity GO:0004983 10 9 0,000 9,1E-03 0,02207126 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 14 9 0,000 9,1E-03 0,0220566 ! prostaglandin receptor activity GO:0004955 11 9 0,000 9,1E-03 0,02204195 ! caspase inhibitor activity GO:0043027 9 9 0,000 9,1E-03 0,02202732 ! adrenoceptor activity GO:0004935 12 9 0,000 9,1E-03 0,02201272 ! regulation of isotype switching GO:0045191 9 9 0,000 9,1E-03 0,02199813 ! positive regulation of leukocyte migration GO:0002687 10 9 0,000 9,1E-03 0,02198356 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 10 9 0,000 9,1E-03 0,02196901 ! positive regulation of ATPase activity GO:0032781 11 9 0,000 9,1E-03 0,02195448 ! nonprotein amino acid metabolic process GO:0019794 19 9 0,000 9,1E-03 0,02193997 ! ionotropic glutamate receptor complex GO:0008328 14 9 0,000 9,1E-03 0,02192548 ! Notch binding GO:0005112 10 9 0,000 9,1E-03 0,02191101 ! ATPase regulator activity GO:0060590 10 9 0,000 9,1E-03 0,02189655 ! gamma-tubulin complex GO:0000930 19 9 0,000 9,1E-03 0,02188212 ! pyrimidine base metabolic process GO:0006206 10 9 0,000 9,1E-03 0,0218677 ! establishment or maintenance of apical/basal cell polarity GO:0035088 10 9 0,000 9,1E-03 0,02185331 ! tubulin-tyrosine ligase activity GO:0004835 10 9 0,000 9,1E-03 0,02183893 ! alcohol dehydrogenase (NAD) activity GO:0004022 10 9 0,000 9,1E-03 0,02182457 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 12 10 0,000 0,01010576 0,02422195 ! oligosaccharide biosynthetic process GO:0009312 10 10 0,000 0,01010576 0,02420605 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 10 0,000 0,01010576 0,02419017 ! sleep GO:0030431 11 10 0,000 0,01010576 0,0241743 ! positive regulation of lipid biosynthetic process GO:0046889 10 10 0,000 0,01010576 0,02415846 ! lipid particle GO:0005811 10 10 0,000 0,01010576 0,02414264 ! filopodium assembly GO:0046847 14 10 0,000 0,01010576 0,02412684 ! UTP metabolic process GO:0046051 12 10 0,000 0,01010576 0,02411106 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 13 10 0,000 0,01010576 0,0240953 ! guanylate kinase activity GO:0004385 14 10 0,000 0,01010576 0,02407956 ! integral to mitochondrial membrane GO:0032592 10 10 0,000 0,01010576 0,02406385 ! COPI coating of Golgi vesicle GO:0048205 11 10 0,000 0,01010576 0,02404815 GO:0048200|Golgi transport vesicle coating, ! platelet alpha granule membrane GO:0031092 11 10 0,000 0,01010576 0,02403247 ! macromolecule transmembrane transporter activity GO:0022884 11 10 0,000 0,01010576 0,02401682 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 10 0,000 0,01010576 0,02400118 ! thyroid hormone receptor coactivator activity GO:0030375 11 10 0,000 0,01010576 0,02398556 GO:0010861|thyroid hormone receptor activator activity, ! regulation of receptor activity GO:0010469 12 10 0,000 0,01010576 0,02396997 ! lung alveolus development GO:0048286 11 10 0,000 0,01010576 0,02395439 ! regulation of chemokine biosynthetic process GO:0045073 11 10 0,000 0,01010576 0,02393884 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01010576 0,0239233 ! negative regulation of striated muscle development GO:0045843 11 10 0,000 0,01010576 0,02390779 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 0,01010576 0,0238923 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 11 10 0,000 0,01010576 0,02387682 ! regulation of mRNA processing GO:0050684 12 10 0,000 0,01010576 0,02386137 ! positive regulation of survival gene product expression GO:0045885 12 10 0,000 0,01010576 0,02384593 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 11 10 0,000 0,01010576 0,02383052 ! transforming growth factor beta binding GO:0050431 11 10 0,000 0,01010576 0,02381512 ! histidine metabolic process GO:0006547 10 10 0,000 0,01010576 0,02379975 GO:0009075|histidine family amino acid metabolic process, ! glucan biosynthetic process GO:0009250 10 10 0,000 0,01010576 0,0237844 GO:0005978|glycogen biosynthetic process, ! endosome organization GO:0007032 13 10 0,000 0,01010576 0,02376906 ! death receptor activity GO:0005035 11 10 0,000 0,01010576 0,02375375 ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 0,01010576 0,02373845 ! entry into host cell GO:0030260 11 10 0,000 0,01010576 0,02372317 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 10 10 0,000 0,01010576 0,02370792 ! filamentous actin GO:0031941 11 10 0,000 0,01010576 0,02369268 ! behavioral fear response GO:0001662 12 10 0,000 0,01010576 0,02367746 GO:0002209|behavioral defense response, ! bone mineralization GO:0030282 12 10 0,000 0,01010576 0,02366227 ! negative regulation of ossification GO:0030279 12 10 0,000 0,01010576 0,02364709 ! phosphatidylcholine biosynthetic process GO:0006656 11 10 0,000 0,01010576 0,02363193 ! macrophage differentiation GO:0030225 11 10 0,000 0,01010576 0,02361679 ! positive regulation of phagocytosis GO:0050766 11 10 0,000 0,01010576 0,02360167 ! recycling endosome membrane GO:0055038 11 10 0,000 0,01010576 0,02358657 ! regulation of fat cell differentiation GO:0045598 11 10 0,000 0,01010576 0,02357149 ! snRNA metabolic process GO:0016073 10 10 0,000 0,01010576 0,02355643 GO:0016180|snRNA processing, ! glycosphingolipid biosynthetic process GO:0006688 11 10 0,000 0,01010576 0,02354139 ! regulation of mitochondrial membrane potential GO:0051881 11 10 0,000 0,01010576 0,02352636 ! purine ribonucleotide catabolic process GO:0009154 10 10 0,000 0,01010576 0,02351136 ! immunoglobulin production during immune response GO:0002381 10 10 0,000 0,01010576 0,02349638 ! nitric oxide metabolic process GO:0046209 20 10 0,000 0,01010576 0,02348141 ! induction of an organ GO:0001759 12 10 0,000 0,01010576 0,02346646 ! response to estradiol stimulus GO:0032355 11 10 0,000 0,01010576 0,02345153 ! synaptic vesicle endocytosis GO:0048488 12 10 0,000 0,01010576 0,02343663 ! negative regulation of MAPKKK cascade GO:0043409 12 10 0,000 0,01010576 0,02342174 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 10 0,000 0,01010576 0,02340687 ! MHC class II receptor activity GO:0032395 14 10 0,000 0,01010576 0,02339201 ! peptidyl-lysine modification GO:0018205 11 10 0,000 0,01010576 0,02337718 ! ribonuclease P activity GO:0004526 10 10 0,000 0,01010576 0,02336237 ! COPI vesicle coat GO:0030126 12 10 0,000 0,01010576 0,02334757 GO:0030663|COPI coated vesicle membrane, ! telomere maintenance via telomere lengthening GO:0010833 21 10 0,000 0,01010576 0,02333279 ! vitamin transporter activity GO:0051183 12 10 0,000 0,01010576 0,02331803 ! snRNA binding GO:0017069 11 10 0,000 0,01010576 0,0233033 ! negative regulation of osteoblast differentiation GO:0045668 12 10 0,000 0,01010576 0,02328857 ! heparan sulfate sulfotransferase activity GO:0034483 10 10 0,000 0,01010576 0,02327387 ! fatty-acid ligase activity GO:0015645 10 10 0,000 0,01010576 0,02325919 ! intramolecular transferase activity, phosphotransferases GO:0016868 11 10 0,000 0,01010576 0,02324452 ! quaternary ammonium group transport GO:0015697 10 10 0,000 0,01010576 0,02322988 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 10 10 0,000 0,01010576 0,02321525 ! metalloenzyme inhibitor activity GO:0048551 11 10 0,000 0,01010576 0,02320064 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! anterior/posterior axis specification GO:0009948 14 10 0,000 0,01010576 0,02318605 ! regulation of RNA splicing GO:0043484 13 10 0,000 0,01010576 0,02317147 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 10 10 0,000 0,01010576 0,02315692 ! trophectodermal cell differentiation GO:0001829 11 10 0,000 0,01010576 0,02314238 ! positive regulation of neuron apoptosis GO:0043525 11 10 0,000 0,01010576 0,02312786 ! extracellular matrix binding GO:0050840 11 10 0,000 0,01010576 0,02311336 ! regulation of synapse structure and activity GO:0050803 11 10 0,000 0,01010576 0,02309888 ! autophagic vacuole formation GO:0000045 11 10 0,000 0,01010576 0,02308442 ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 0,01010576 0,02306997 ! negative regulation of cell projection organization GO:0031345 14 10 0,000 0,01010576 0,02305554 ! negative regulation of cellular catabolic process GO:0031330 11 10 0,000 0,01010576 0,02304113 ! rough endoplasmic reticulum membrane GO:0030867 10 10 0,000 0,01010576 0,02302674 ! thyroid gland development GO:0030878 12 10 0,000 0,01010576 0,02301237 ! DNA bending activity GO:0008301 11 10 0,000 0,01010576 0,02299801 ! neutral lipid biosynthetic process GO:0046460 10 10 0,000 0,01010576 0,02298367 GO:0046463|acylglycerol biosynthetic process, ! embryonic hindlimb morphogenesis GO:0035116 11 10 0,000 0,01010576 0,02296935 ! embryonic forelimb morphogenesis GO:0035115 12 10 0,000 0,01010576 0,02295505 ! regulation of glucan biosynthetic process GO:0010962 10 10 0,000 0,01010576 0,02294077 GO:0005979|regulation of glycogen biosynthetic process, GO:0032885|regulation of polysaccharide biosynthetic process, ! secondary active sulfate transmembrane transporter activity GO:0008271 11 10 0,000 0,01010576 0,0229265 ! regulation of glycolysis GO:0006110 11 10 0,000 0,01010576 0,02291225 ! nucleotidase activity GO:0008252 10 10 0,000 0,01010576 0,02289802 ! phosphatidylinositol phosphate kinase activity GO:0016307 11 10 0,000 0,01010576 0,02288381 ! dipeptidyl-peptidase activity GO:0008239 12 10 0,000 0,01010576 0,02286961 ! androgen metabolic process GO:0008209 11 10 0,000 0,01010576 0,02285543 ! lateral plasma membrane GO:0016328 13 10 0,000 0,01010576 0,02284127 ! MAP kinase kinase activity GO:0004708 12 10 0,000 0,01010576 0,02282713 ! cation:amino acid symporter activity GO:0005416 12 10 0,000 0,01010576 0,022813 ! startle response GO:0001964 13 10 0,000 0,01010576 0,02279889 ! amyloid precursor protein metabolic process GO:0042982 12 10 0,000 0,01010576 0,0227848 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 12 10 0,000 0,01010576 0,02277073 ! positive regulation of endothelial cell proliferation GO:0001938 13 10 0,000 0,01010576 0,02275667 ! 3'-5'-exoribonuclease activity GO:0000175 10 10 0,000 0,01010576 0,02274264 ! spinal cord patterning GO:0021511 12 10 0,000 0,01010576 0,02272861 ! peptide or protein amino-terminal blocking GO:0018409 11 10 0,000 0,01010576 0,02271461 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 10 10 0,000 0,01010576 0,02270062 GO:0033549|MAP kinase phosphatase activity, ! response to X-ray GO:0010165 11 10 0,000 0,01010576 0,02268665 ! embryonic eye morphogenesis GO:0048048 14 10 0,000 0,01010576 0,0226727 ! sodium:potassium-exchanging ATPase activity GO:0005391 12 10 0,000 0,01010576 0,02265877 ! zinc ion transmembrane transporter activity GO:0005385 13 10 0,000 0,01010576 0,02264485 ! positive regulation of glycogen metabolic process GO:0070875 11 10 0,000 0,01010576 0,02263095 ! glucose transmembrane transporter activity GO:0005355 10 10 0,000 0,01010576 0,02261706 ! regulation of intracellular pH GO:0051453 10 10 0,000 0,01010576 0,0226032 ! retrograde transport, endosome to Golgi GO:0042147 12 10 0,000 0,01010576 0,02258935 ! regulation of multicellular organismal metabolic process GO:0044246 11 10 0,000 0,01010576 0,02257551 ! adult heart development GO:0007512 14 10 0,000 0,01010576 0,0225617 ! neuromuscular junction development GO:0007528 12 10 0,000 0,01010576 0,0225479 ! carbohydrate phosphatase activity GO:0019203 11 10 0,000 0,01010576 0,02253412 ! O-methyltransferase activity GO:0008171 10 10 0,000 0,01010576 0,02252035 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 10 10 0,000 0,01010576 0,0225066 ! signalosome GO:0008180 10 10 0,000 0,01010576 0,02249287 ! lysophospholipase activity GO:0004622 19 10 0,000 0,01010576 0,02247915 ! prefoldin complex GO:0016272 10 10 0,000 0,01010576 0,02246546 ! alpha-beta T cell differentiation GO:0046632 12 10 0,000 0,01010576 0,02245177 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 10 0,000 0,01010576 0,02243811 ! positive regulation of T cell mediated immunity GO:0002711 10 10 0,000 0,01010576 0,02242446 ! nucleoside bisphosphate metabolic process GO:0033865 10 10 0,000 0,01010576 0,02241083 ! endocytic vesicle membrane GO:0030666 10 10 0,000 0,01010576 0,02239721 ! gland morphogenesis GO:0022612 11 10 0,000 0,01010576 0,02238361 ! icosanoid receptor activity GO:0004953 13 10 0,000 0,01010576 0,02237003 GO:0004954|prostanoid receptor activity, ! regulation of macrophage activation GO:0043030 11 10 0,000 0,01010576 0,02235647 ! peptide transporter activity GO:0015197 10 10 0,000 0,01010576 0,02234292 ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 10 10 0,000 0,01010576 0,02232938 ! regulation of leukocyte migration GO:0002685 11 10 0,000 0,01010576 0,02231587 ! muscle maintenance GO:0046716 10 10 0,000 0,01010576 0,02230237 ! acid secretion GO:0046717 12 10 0,000 0,01010576 0,02228888 ! retinoid-X receptor activity GO:0004886 11 10 0,000 0,01010576 0,02227542 ! catecholamine biosynthetic process GO:0042423 11 10 0,000 0,01010576 0,02226196 ! thyroid hormone metabolic process GO:0042403 11 10 0,000 0,01010576 0,02224853 ! GTPase inhibitor activity GO:0005095 21 10 0,000 0,01010576 0,02223511 ! somatic recombination of immunoglobulin gene segments GO:0016447 10 10 0,000 0,01010576 0,02222171 ! pattern recognition receptor activity GO:0008329 10 10 0,000 0,01010576 0,02220832 ! quinone cofactor metabolic process GO:0042375 11 10 0,000 0,01010576 0,02219495 ! regulation of organic acid transport GO:0032890 12 10 0,000 0,01010576 0,0221816 ! platelet-derived growth factor receptor binding GO:0005161 14 10 0,000 0,01010576 0,02216826 ! C-acyltransferase activity GO:0016408 12 10 0,000 0,01010576 0,02215494 ! cAMP-dependent protein kinase complex GO:0005952 12 10 0,000 0,01010576 0,02214163 ! water channel activity GO:0015250 15 10 0,000 0,01010576 0,02212834 ! phospholipase inhibitor activity GO:0004859 10 10 0,000 0,01010576 0,02211506 ! regulation of embryonic development GO:0045995 12 10 0,000 0,01010576 0,02210181 ! acrosome reaction GO:0007340 12 10 0,000 0,01010576 0,02208856 ! mitochondrion localization GO:0051646 10 10 0,000 0,01010576 0,02207534 ! cilium part GO:0044441 10 10 0,000 0,01010576 0,02206213 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 12 11 0,000 0,011111 0,02424218 ! 'de novo' posttranslational protein folding GO:0051084 11 11 0,000 0,011111 0,02422769 ! negative regulation of blood pressure GO:0045776 13 11 0,000 0,011111 0,02421321 ! centriole GO:0005814 11 11 0,000 0,011111 0,02419876 ! cadmium ion binding GO:0046870 15 11 0,000 0,011111 0,02418432 ! hemoglobin complex GO:0005833 13 11 0,000 0,011111 0,0241699 ! CTP metabolic process GO:0046036 13 11 0,000 0,011111 0,02415549 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0009148|pyrimidine nucleoside triphosphate biosynthetic process, ! regulation of neurotransmitter secretion GO:0046928 12 11 0,000 0,011111 0,02414111 ! response to pain GO:0048265 12 11 0,000 0,011111 0,02412674 ! regulation of viral genome replication GO:0045069 13 11 0,000 0,011111 0,02411238 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 11 11 0,000 0,011111 0,02409805 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 12 11 0,000 0,011111 0,02408373 ! nucleotide-sugar metabolic process GO:0009225 13 11 0,000 0,011111 0,02406943 ! regulation of catecholamine secretion GO:0050433 12 11 0,000 0,011111 0,02405514 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 0,011111 0,02404088 ! peptide antigen binding GO:0042605 14 11 0,000 0,011111 0,02402663 ! polyamine metabolic process GO:0006595 11 11 0,000 0,011111 0,02401239 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 13 11 0,000 0,011111 0,02399818 GO:0045125|bioactive lipid receptor activity, ! nucleobase biosynthetic process GO:0046112 13 11 0,000 0,011111 0,02398398 ! regulation of calcium ion transport into cytosol GO:0010522 15 11 0,000 0,011111 0,02396979 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 12 11 0,000 0,011111 0,02395563 GO:0002717|positive regulation of natural killer cell mediated immunity, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 12 11 0,000 0,011111 0,02394148 ! protein homotetramerization GO:0051289 13 11 0,000 0,011111 0,02392734 ! regulation of gliogenesis GO:0014013 13 11 0,000 0,011111 0,02391323 GO:0045685|regulation of glial cell differentiation, ! oligodendrocyte development GO:0014003 11 11 0,000 0,011111 0,02389913 ! cytoskeletal adaptor activity GO:0008093 17 11 0,000 0,011111 0,02388504 ! regulation of circadian rhythm GO:0042752 11 11 0,000 0,011111 0,02387098 ! low-density lipoprotein receptor binding GO:0050750 11 11 0,000 0,011111 0,02385693 ! response to dsRNA GO:0043331 21 11 0,000 0,011111 0,02384289 ! response to amine stimulus GO:0014075 15 11 0,000 0,011111 0,02382888 GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 14 11 0,000 0,011111 0,02381488 ! sphingomyelin metabolic process GO:0006684 13 11 0,000 0,011111 0,02380089 ! cell wall macromolecule catabolic process GO:0016998 14 11 0,000 0,011111 0,02378692 ! spinal cord motor neuron differentiation GO:0021522 12 11 0,000 0,011111 0,02377297 ! retinal binding GO:0016918 11 11 0,000 0,011111 0,02375904 ! leukocyte activation during immune response GO:0002366 11 11 0,000 0,011111 0,02374512 GO:0002263|cell activation during immune response, ! regulation of sterol transport GO:0032371 12 11 0,000 0,011111 0,02373122 GO:0032374|regulation of cholesterol transport, ! beta-tubulin binding GO:0048487 14 11 0,000 0,011111 0,02371733 ! autonomic nervous system development GO:0048483 12 11 0,000 0,011111 0,02370346 ! negative regulation of lipid transport GO:0032369 12 11 0,000 0,011111 0,02368961 ! photoreceptor outer segment GO:0001750 12 11 0,000 0,011111 0,02367577 ! positive regulation of interleukin-1 secretion GO:0050716 12 11 0,000 0,011111 0,02366195 ! peptidyl-threonine modification GO:0018210 15 11 0,000 0,011111 0,02364814 ! clathrin coat of trans-Golgi network vesicle GO:0030130 15 11 0,000 0,011111 0,02363435 ! regulation of interleukin-1 beta secretion GO:0050706 12 11 0,000 0,011111 0,02362058 ! regulation of epidermis development GO:0045682 14 11 0,000 0,011111 0,02360683 ! positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 11 11 0,000 0,011111 0,02359308 ! midbrain development GO:0030901 12 11 0,000 0,011111 0,02357936 ! musculoskeletal movement GO:0050881 12 11 0,000 0,011111 0,02356565 GO:0050879|multicellular organismal movement, ! histone deacetylase binding GO:0042826 11 11 0,000 0,011111 0,02355196 ! regulation of RNA stability GO:0043487 13 11 0,000 0,011111 0,02353828 GO:0043488|regulation of mRNA stability, ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 11 11 0,000 0,011111 0,02352462 ! cell killing GO:0001906 13 11 0,000 0,011111 0,02351097 ! regulation of cellular carbohydrate catabolic process GO:0043471 13 11 0,000 0,011111 0,02349734 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 12 11 0,000 0,011111 0,02348373 ! carbon-sulfur lyase activity GO:0016846 11 11 0,000 0,011111 0,02347013 ! regulation of blood vessel endothelial cell migration GO:0043535 13 11 0,000 0,011111 0,02345655 ! folic acid binding GO:0005542 12 11 0,000 0,011111 0,02344298 ! mRNA 3'-end processing GO:0031124 12 11 0,000 0,011111 0,02342943 ! regulation of calcium-mediated signaling GO:0050848 13 11 0,000 0,011111 0,0234159 ! positive regulation of protein polymerization GO:0032273 11 11 0,000 0,011111 0,02340238 ! microspike assembly GO:0030035 15 11 0,000 0,011111 0,02338887 ! lamellipodium assembly GO:0030032 22 11 0,000 0,011111 0,02337539 ! fibrillar collagen GO:0005583 12 11 0,000 0,011111 0,02336191 ! inner ear receptor cell differentiation GO:0060113 12 11 0,000 0,011111 0,02334846 ! cytoplasmic sequestering of protein GO:0051220 12 11 0,000 0,011111 0,02333501 ! negative regulation of muscle development GO:0048635 13 11 0,000 0,011111 0,02332159 ! very-long-chain fatty acid metabolic process GO:0000038 12 11 0,000 0,011111 0,02330818 ! synaptonemal complex GO:0000795 11 11 0,000 0,011111 0,02329478 ! reproductive cellular process GO:0048610 13 11 0,000 0,011111 0,0232814 ! cortical actin cytoskeleton organization GO:0030866 12 11 0,000 0,011111 0,02326804 ! Golgi vesicle budding GO:0048194 12 11 0,000 0,011111 0,02325469 ! response to cAMP GO:0051591 11 11 0,000 0,011111 0,02324135 ! detection of mechanical stimulus GO:0050982 13 11 0,000 0,011111 0,02322803 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 13 11 0,000 0,011111 0,02321473 ! regulation of cell projection assembly GO:0060491 11 11 0,000 0,011111 0,02320144 ! negative regulation of transcription factor import into nucleus GO:0042992 11 11 0,000 0,011111 0,02318817 ! positive regulation of transcription factor import into nucleus GO:0042993 13 11 0,000 0,011111 0,02317491 ! macromolecular complex remodeling GO:0034367 11 11 0,000 0,011111 0,02316167 GO:0034368|protein-lipid complex remodeling, GO:0034369|plasma lipoprotein particle remodeling, ! protein serine/threonine/tyrosine kinase activity GO:0004712 13 11 0,000 0,011111 0,02314844 ! glycerol ether biosynthetic process GO:0046504 11 11 0,000 0,011111 0,02313523 ! drug transport GO:0015893 12 11 0,000 0,011111 0,02312203 ! FMN binding GO:0010181 12 11 0,000 0,011111 0,02310885 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 11 0,000 0,011111 0,02309568 ! water transporter activity GO:0005372 17 11 0,000 0,011111 0,02308253 ! regulation of glycogen metabolic process GO:0070873 12 11 0,000 0,011111 0,02306939 GO:0032881|regulation of polysaccharide metabolic process, ! substrate-bound cell migration GO:0006929 13 11 0,000 0,011111 0,02305627 ! multicellular organism growth GO:0035264 12 11 0,000 0,011111 0,02304316 ! integrator complex GO:0032039 11 11 0,000 0,011111 0,02303007 ! L-glutamate transmembrane transporter activity GO:0005313 13 11 0,000 0,011111 0,02301699 GO:0015172|acidic amino acid transmembrane transporter activity, ! DNA integration GO:0015074 11 11 0,000 0,011111 0,02300393 ! brush border membrane GO:0031526 12 11 0,000 0,011111 0,02299088 ! actin cytoskeleton reorganization GO:0031532 14 11 0,000 0,011111 0,02297785 ! macroautophagy GO:0016236 12 11 0,000 0,011111 0,02296483 ! protein disulfide oxidoreductase activity GO:0015035 11 11 0,000 0,011111 0,02295182 ! neuromuscular junction GO:0031594 12 11 0,000 0,011111 0,02293883 ! positive regulation of peptide secretion GO:0002793 13 11 0,000 0,011111 0,02292586 ! positive regulation of alpha-beta T cell activation GO:0046635 12 11 0,000 0,011111 0,0229129 ! organic anion transmembrane transporter activity GO:0008514 11 11 0,000 0,011111 0,02289995 ! response to antibiotic GO:0046677 13 11 0,000 0,011111 0,02288702 ! protein-hormone receptor activity GO:0016500 12 11 0,000 0,011111 0,02287411 ! bile acid transmembrane transporter activity GO:0015125 13 11 0,000 0,011111 0,02286121 ! proteasome accessory complex GO:0022624 11 11 0,000 0,011111 0,02284832 ! neuroblast proliferation GO:0007405 13 11 0,000 0,011111 0,02283545 ! non-G-protein coupled 7TM receptor activity GO:0004926 14 11 0,000 0,011111 0,02282259 ! negative regulation of neurological system process GO:0031645 13 11 0,000 0,011111 0,02280975 ! nitric oxide mediated signal transduction GO:0007263 12 11 0,000 0,011111 0,02279692 ! protein kinase C binding GO:0005080 11 11 0,000 0,011111 0,0227841 ! transforming growth factor beta receptor, cytoplasmic mediator activity GO:0005072 12 11 0,000 0,011111 0,0227713 ! male genitalia development GO:0030539 15 11 0,000 0,011111 0,02275852 ! receptor inhibitor activity GO:0030547 12 11 0,000 0,011111 0,02274575 GO:0048019|receptor antagonist activity, ! estrogen receptor signaling pathway GO:0030520 12 11 0,000 0,011111 0,02273299 ! L-fucose metabolic process GO:0042354 13 11 0,000 0,011111 0,02272025 ! palmitoyltransferase activity GO:0016409 11 11 0,000 0,011111 0,02270752 ! arylsulfatase activity GO:0004065 12 11 0,000 0,011111 0,0226948 ! sterol transporter activity GO:0015248 11 11 0,000 0,011111 0,0226821 ! response to nicotine GO:0035094 13 11 0,000 0,011111 0,02266942 ! adenylate cyclase activity GO:0004016 11 11 0,000 0,011111 0,02265675 ! rRNA transcription GO:0009303 12 12 0,000 0,01211527 0,02469078 ! ER-associated protein catabolic process GO:0030433 14 12 0,000 0,01211527 0,02467699 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of blood pressure GO:0045777 15 12 0,000 0,01211527 0,02466322 ! superoxide anion generation GO:0042554 12 12 0,000 0,01211527 0,02464947 ! pteridine and derivative biosynthetic process GO:0042559 22 12 0,000 0,01211527 0,02463573 ! regulation of chemokine production GO:0032642 13 12 0,000 0,01211527 0,024622 ! male meiosis GO:0007140 12 12 0,000 0,01211527 0,02460829 ! signal complex assembly GO:0007172 15 12 0,000 0,01211527 0,0245946 ! GTP metabolic process GO:0046039 14 12 0,000 0,01211527 0,02458092 ! retina morphogenesis in camera-type eye GO:0060042 16 12 0,000 0,01211527 0,02456726 ! hair follicle morphogenesis GO:0031069 14 12 0,000 0,01211527 0,02455361 ! voltage-gated sodium channel complex GO:0001518 15 12 0,000 0,01211527 0,02453998 GO:0034706|sodium channel complex, ! RNA polyadenylation GO:0043631 13 12 0,000 0,01211527 0,02452636 ! cartilage condensation GO:0001502 14 12 0,000 0,01211527 0,02451275 ! polysome GO:0005844 14 12 0,000 0,01211527 0,02449917 ! hippocampus development GO:0021766 13 12 0,000 0,01211527 0,02448559 ! lipoprotein receptor binding GO:0070325 13 12 0,000 0,01211527 0,02447204 ! beta-amyloid binding GO:0001540 12 12 0,000 0,01211527 0,02445849 ! negative regulation of endocytosis GO:0045806 15 12 0,000 0,01211527 0,02444496 ! regulation of interferon-gamma biosynthetic process GO:0045072 15 12 0,000 0,01211527 0,02443145 ! regulation of exit from mitosis GO:0007096 31 12 0,000 0,01211527 0,02441795 ! chylomicron GO:0042627 13 12 0,000 0,01211527 0,02440447 ! T cell selection GO:0045058 22 12 0,000 0,01211527 0,024391 ! negative regulation of proteolysis GO:0045861 12 12 0,000 0,01211527 0,02437755 ! glycolipid biosynthetic process GO:0009247 13 12 0,000 0,01211527 0,02436411 ! WW domain binding GO:0050699 12 12 0,000 0,01211527 0,02435069 ! methionine metabolic process GO:0006555 14 12 0,000 0,01211527 0,02433728 ! nuclear heterochromatin GO:0005720 12 12 0,000 0,01211527 0,02432388 ! glycine metabolic process GO:0006544 14 12 0,000 0,01211527 0,0243105 ! plasma membrane organization GO:0007009 12 12 0,000 0,01211527 0,02429714 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01211527 0,02428379 ! ribonucleotide catabolic process GO:0009261 12 12 0,000 0,01211527 0,02427045 ! Golgi organization GO:0007030 15 12 0,000 0,01211527 0,02425713 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 0,01211527 0,02424383 ! integral to peroxisomal membrane GO:0005779 12 12 0,000 0,01211527 0,02423054 ! integral to membrane of membrane fraction GO:0000299 13 12 0,000 0,01211527 0,02421726 ! regulation of the force of heart contraction GO:0002026 13 12 0,000 0,01211527 0,024204 ! temperature homeostasis GO:0001659 13 12 0,000 0,01211527 0,02419075 ! negative regulation of mitotic cell cycle GO:0045930 15 12 0,000 0,01211527 0,02417751 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 0,01211527 0,0241643 ! lipoprotein receptor activity GO:0030228 12 12 0,000 0,01211527 0,02415109 ! cotranslational protein targeting to membrane GO:0006613 14 12 0,000 0,01211527 0,0241379 ! axon cargo transport GO:0008088 13 12 0,000 0,01211527 0,02412473 ! regulation of phagocytosis GO:0050764 14 12 0,000 0,01211527 0,02411156 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 12 0,000 0,01211527 0,02409842 ! nucleoside triphosphate catabolic process GO:0009143 12 12 0,000 0,01211527 0,02408528 ! transcription elongation factor complex GO:0008023 12 12 0,000 0,01211527 0,02407217 ! basal lamina GO:0005605 12 12 0,000 0,01211527 0,02405906 ! regulation of interleukin-1 secretion GO:0050704 13 12 0,000 0,01211527 0,02404597 ! pancreatic ribonuclease activity GO:0004522 12 12 0,000 0,01211527 0,0240329 ! tRNA-specific ribonuclease activity GO:0004549 12 12 0,000 0,01211527 0,02401983 ! biomineral formation GO:0031214 14 12 0,000 0,01211527 0,02400679 ! water homeostasis GO:0030104 12 12 0,000 0,01211527 0,02399375 ! promoter binding GO:0010843 14 12 0,000 0,01211527 0,02398074 ! regulation of erythrocyte differentiation GO:0045646 15 12 0,000 0,01211527 0,02396773 ! intestinal absorption GO:0050892 14 12 0,000 0,01211527 0,02395474 ! pseudouridine synthase activity GO:0009982 12 12 0,000 0,01211527 0,02394176 ! oocyte differentiation GO:0009994 13 12 0,000 0,01211527 0,0239288 ! oxygen transport GO:0015671 13 12 0,000 0,01211527 0,02391585 GO:0005344|oxygen transporter activity, ! thymus development GO:0048538 13 12 0,000 0,01211527 0,02390292 ! cholesterol efflux GO:0033344 13 12 0,000 0,01211527 0,02389 ! digestive tract morphogenesis GO:0048546 14 12 0,000 0,01211527 0,02387709 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! racemase and epimerase activity GO:0016854 13 12 0,000 0,01211527 0,0238642 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 14 12 0,000 0,01211527 0,02385132 ! tropomyosin binding GO:0005523 12 12 0,000 0,01211527 0,02383846 ! blastocyst formation GO:0001825 13 12 0,000 0,01211527 0,0238256 ! regulation of telomere maintenance GO:0032204 16 12 0,000 0,01211527 0,02381277 ! internal side of plasma membrane GO:0009898 16 12 0,000 0,01211527 0,02379994 ! mannose binding GO:0005537 13 12 0,000 0,01211527 0,02378713 ! phosphoprotein binding GO:0051219 14 12 0,000 0,01211527 0,02377434 ! defense response to fungus GO:0050832 12 12 0,000 0,01211527 0,02376156 ! embryonic placenta development GO:0001892 16 12 0,000 0,01211527 0,02374879 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 0,01211527 0,02373603 ! cell wall macromolecule metabolic process GO:0044036 15 12 0,000 0,01211527 0,02372329 ! acyl-CoA binding GO:0000062 12 12 0,000 0,01211527 0,02371057 ! cortical cytoskeleton organization GO:0030865 13 12 0,000 0,01211527 0,02369785 ! regulation of nitric-oxide synthase activity GO:0050999 12 12 0,000 0,01211527 0,02368515 ! copper ion transport GO:0006825 12 12 0,000 0,01211527 0,02367247 ! calcium ion transport into cytosol GO:0060402 19 12 0,000 0,01211527 0,02365979 ! inositol metabolic process GO:0006020 21 12 0,000 0,01211527 0,02364714 ! vesicle targeting, to, from or within Golgi GO:0048199 13 12 0,000 0,01211527 0,02363449 ! forelimb morphogenesis GO:0035136 15 12 0,000 0,01211527 0,02362186 ! protein complex disassembly GO:0043241 15 12 0,000 0,01211527 0,02360924 GO:0043624|cellular protein complex disassembly, ! ion channel inhibitor activity GO:0008200 15 12 0,000 0,01211527 0,02359663 GO:0016248|channel inhibitor activity, ! low-density lipoprotein particle GO:0034362 13 12 0,000 0,01211527 0,02358404 ! lipoprotein particle clearance GO:0034381 14 12 0,000 0,01211527 0,02357146 ! receptor signaling protein tyrosine kinase activity GO:0004716 14 12 0,000 0,01211527 0,0235589 ! endothelial cell differentiation GO:0045446 15 12 0,000 0,01211527 0,02354635 ! exosome (RNase complex) GO:0000178 13 12 0,000 0,01211527 0,02353381 ! DNA N-glycosylase activity GO:0019104 12 12 0,000 0,01211527 0,02352129 ! endoderm development GO:0007492 13 12 0,000 0,01211527 0,02350877 ! positive regulation of Ras protein signal transduction GO:0046579 25 12 0,000 0,01211527 0,02349628 ! focal adhesion formation GO:0048041 16 12 0,000 0,01211527 0,02348379 ! T cell receptor complex GO:0042101 31 12 0,000 0,01211527 0,02347132 ! cellular carbohydrate catabolic process GO:0044275 25 12 0,000 0,01211527 0,02345886 ! dicarboxylic acid transmembrane transporter activity GO:0005310 14 12 0,000 0,01211527 0,02344642 ! CoA hydrolase activity GO:0016289 14 12 0,000 0,01211527 0,02343399 ! histone acetyltransferase complex GO:0000123 14 12 0,000 0,01211527 0,02342157 ! regulation of alpha-beta T cell differentiation GO:0046637 13 12 0,000 0,01211527 0,02340916 ! alpha-beta T cell activation GO:0046631 14 12 0,000 0,01211527 0,02339677 ! retinol binding GO:0019841 12 12 0,000 0,01211527 0,02338439 ! regulation of organ growth GO:0046620 12 12 0,000 0,01211527 0,02337202 ! regulation of natural killer cell mediated immunity GO:0002715 13 12 0,000 0,01211527 0,02335967 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! vasoconstriction GO:0042310 13 12 0,000 0,01211527 0,02334733 ! histone acetylation GO:0016573 13 12 0,000 0,01211527 0,023335 ! ribosome binding GO:0043022 13 12 0,000 0,01211527 0,02332269 ! delayed rectifier potassium channel activity GO:0005251 14 12 0,000 0,01211527 0,02331039 ! organic cation transmembrane transporter activity GO:0015101 12 12 0,000 0,01211527 0,0232981 ! phosphate transmembrane transporter activity GO:0015114 14 12 0,000 0,01211527 0,02328583 ! tissue regeneration GO:0042246 12 12 0,000 0,01211527 0,02327356 ! sulfate transmembrane transporter activity GO:0015116 13 12 0,000 0,01211527 0,02326131 ! adenylyltransferase activity GO:0070566 13 12 0,000 0,01211527 0,02324908 ! germ cell nucleus GO:0043073 14 12 0,000 0,01211527 0,02323685 ! trans-Golgi network transport vesicle membrane GO:0012510 16 12 0,000 0,01211527 0,02322464 ! hexose transmembrane transporter activity GO:0015149 12 12 0,000 0,01211527 0,02321245 ! hexosaminidase activity GO:0015929 12 12 0,000 0,01211527 0,02320026 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 0,01211527 0,02318809 ! activation of NF-kappaB-inducing kinase activity GO:0007250 14 12 0,000 0,01211527 0,02317593 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 13 12 0,000 0,01211527 0,02316378 ! dopamine metabolic process GO:0042417 15 12 0,000 0,01211527 0,02315165 ! somatic diversification of immunoglobulins GO:0016445 12 12 0,000 0,01211527 0,02313953 ! phosphoinositide 3-kinase activity GO:0035004 14 12 0,000 0,01211527 0,02312742 ! insulin-like growth factor receptor binding GO:0005159 14 12 0,000 0,01211527 0,02311532 ! bacterial binding GO:0008367 14 12 0,000 0,01211527 0,02310324 ! steroid hydroxylase activity GO:0008395 12 12 0,000 0,01211527 0,02309117 ! cardiac cell differentiation GO:0035051 16 12 0,000 0,01211527 0,02307911 ! phosphoinositide 3-kinase complex GO:0005942 14 12 0,000 0,01211527 0,02306706 ! localization within membrane GO:0051668 13 12 0,000 0,01211527 0,02305503 ! microtubule-based flagellum GO:0009434 12 12 0,000 0,01211527 0,02304301 ! axoneme part GO:0044447 12 12 0,000 0,01211527 0,023031 ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01311857 0,02492529 ! neuron maturation GO:0042551 14 13 0,000 0,01311857 0,02491231 ! positive regulation of small GTPase mediated signal transduction GO:0051057 26 13 0,000 0,01311857 0,02489935 ! negative regulation of bone remodeling GO:0046851 15 13 0,000 0,01311857 0,0248864 ! bone remodeling GO:0046849 14 13 0,000 0,01311857 0,02487347 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01311857 0,02486054 ! regulation of receptor-mediated endocytosis GO:0048259 15 13 0,000 0,01311857 0,02484764 ! striated muscle thin filament GO:0005865 14 13 0,000 0,01311857 0,02483474 ! patterning of blood vessels GO:0001569 15 13 0,000 0,01311857 0,02482186 ! organelle fusion GO:0048284 16 13 0,000 0,01311857 0,02480899 ! palate development GO:0060021 15 13 0,000 0,01311857 0,02479614 ! induction of apoptosis via death domain receptors GO:0008625 16 13 0,000 0,01311857 0,0247833 ! arginine metabolic process GO:0006525 14 13 0,000 0,01311857 0,02477047 ! ER-Golgi intermediate compartment membrane GO:0033116 23 13 0,000 0,01311857 0,02475766 ! tyrosine metabolic process GO:0006570 15 13 0,000 0,01311857 0,02474485 ! response to retinoic acid GO:0032526 17 13 0,000 0,01311857 0,02473207 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 15 13 0,000 0,01311857 0,02471929 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lipase inhibitor activity GO:0055102 14 13 0,000 0,01311857 0,02470653 ! negative regulation of endothelial cell migration GO:0010596 15 13 0,000 0,01311857 0,02469378 ! fear response GO:0042596 15 13 0,000 0,01311857 0,02468105 ! epithelial cell development GO:0002064 22 13 0,000 0,01311857 0,02466832 ! branching involved in ureteric bud morphogenesis GO:0001658 14 13 0,000 0,01311857 0,02465562 GO:0060675|ureteric bud morphogenesis, ! positive regulation of fatty acid metabolic process GO:0045923 14 13 0,000 0,01311857 0,02464292 ! protein kinase activator activity GO:0030295 17 13 0,000 0,01311857 0,02463024 ! heparan sulfate proteoglycan metabolic process GO:0030201 13 13 0,000 0,01311857 0,02461757 ! positive regulation of foam cell differentiation GO:0010744 16 13 0,000 0,01311857 0,02460491 ! protein targeting to peroxisome GO:0006625 13 13 0,000 0,01311857 0,02459227 ! NLS-bearing substrate import into nucleus GO:0006607 15 13 0,000 0,01311857 0,02457963 ! cranial nerve development GO:0021545 15 13 0,000 0,01311857 0,02456702 ! eye photoreceptor cell differentiation GO:0001754 17 13 0,000 0,01311857 0,02455441 GO:0042462|eye photoreceptor cell development, ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01311857 0,02454182 ! MHC class I receptor activity GO:0032393 20 13 0,000 0,01311857 0,02452924 ! exoribonuclease activity GO:0004532 13 13 0,000 0,01311857 0,02451667 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! intrinsic to peroxisomal membrane GO:0031231 13 13 0,000 0,01311857 0,02450412 ! COPI-coated vesicle GO:0030137 15 13 0,000 0,01311857 0,02449158 ! cofactor transporter activity GO:0051184 15 13 0,000 0,01311857 0,02447905 ! NADP metabolic process GO:0006739 15 13 0,000 0,01311857 0,02446654 ! negative regulation of macrophage differentiation GO:0045650 16 13 0,000 0,01311857 0,02445404 ! regulation of osteoclast differentiation GO:0045670 15 13 0,000 0,01311857 0,02444155 ! aromatic amino acid family catabolic process GO:0009074 13 13 0,000 0,01311857 0,02442907 ! eukaryotic cell surface binding GO:0043499 15 13 0,000 0,01311857 0,02441661 ! proximal/distal pattern formation GO:0009954 15 13 0,000 0,01311857 0,02440416 ! positive regulation of JNK cascade GO:0046330 17 13 0,000 0,01311857 0,02439172 ! positive regulation of glucose import GO:0046326 16 13 0,000 0,01311857 0,02437929 GO:0010828|positive regulation of glucose transport, ! epithelial to mesenchymal transition GO:0001837 13 13 0,000 0,01311857 0,02436688 ! ADP binding GO:0043531 15 13 0,000 0,01311857 0,02435448 ! defense response to Gram-positive bacterium GO:0050830 14 13 0,000 0,01311857 0,02434209 ! mismatched DNA binding GO:0030983 13 13 0,000 0,01311857 0,02432971 ! positive regulation of synaptic transmission GO:0050806 15 13 0,000 0,01311857 0,02431735 ! neuron fate specification GO:0048665 25 13 0,000 0,01311857 0,024305 ! N-terminal protein amino acid modification GO:0031365 14 13 0,000 0,01311857 0,02429266 ! dicarboxylic acid transport GO:0006835 15 13 0,000 0,01311857 0,02428034 ! water transport GO:0006833 18 13 0,000 0,01311857 0,02426803 GO:0042044|fluid transport, ! replisome GO:0030894 24 13 0,000 0,01311857 0,02425573 GO:0043601|nuclear replisome, ! cytosolic calcium ion transport GO:0060401 20 13 0,000 0,01311857 0,02424344 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01311857 0,02423116 ! inorganic anion exchanger activity GO:0005452 13 13 0,000 0,01311857 0,0242189 ! negative regulation of ion transport GO:0043271 15 13 0,000 0,01311857 0,02420665 ! retinoic acid receptor binding GO:0042974 14 13 0,000 0,01311857 0,02419441 ! blood vessel remodeling GO:0001974 16 13 0,000 0,01311857 0,02418219 ! myoblast differentiation GO:0045445 15 13 0,000 0,01311857 0,02416997 ! ventral spinal cord development GO:0021517 16 13 0,000 0,01311857 0,02415777 ! prenyltransferase activity GO:0004659 15 13 0,000 0,01311857 0,02414558 ! activation of MAPKK activity GO:0000186 13 13 0,000 0,01311857 0,02413341 ! protein histidine kinase activity GO:0004673 15 13 0,000 0,01311857 0,02412124 GO:0000155|two-component sensor activity, ! cullin-RING ubiquitin ligase complex GO:0031461 13 13 0,000 0,01311857 0,02410909 ! regulation of skeletal muscle fiber development GO:0048742 16 13 0,000 0,01311857 0,02409695 ! acyl-CoA dehydrogenase activity GO:0003995 14 13 0,000 0,01311857 0,02408483 ! exocrine system development GO:0035272 14 13 0,000 0,01311857 0,02407271 ! membrane protein proteolysis GO:0033619 14 13 0,000 0,01311857 0,02406061 GO:0006509|membrane protein ectodomain proteolysis, ! organic alcohol transport GO:0015850 17 13 0,000 0,01311857 0,02404852 ! calcium ion transmembrane transporter activity GO:0015085 15 13 0,000 0,01311857 0,02403644 ! L-glutamate transport GO:0015813 14 13 0,000 0,01311857 0,02402437 GO:0015800|acidic amino acid transport, ! embryo implantation GO:0007566 17 13 0,000 0,01311857 0,02401232 ! G1/S transition checkpoint GO:0031575 14 13 0,000 0,01311857 0,02400028 ! immunoglobulin binding GO:0019865 14 13 0,000 0,01311857 0,02398825 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,01311857 0,02397623 ! regulation of T cell mediated immunity GO:0002709 17 13 0,000 0,01311857 0,02396422 ! DNA unwinding during replication GO:0006268 14 13 0,000 0,01311857 0,02395223 ! genitalia development GO:0048806 18 13 0,000 0,01311857 0,02394024 ! regulation of interleukin-8 production GO:0032677 15 13 0,000 0,01311857 0,02392827 ! regulation of interleukin-12 production GO:0032655 13 13 0,000 0,01311857 0,02391632 ! MHC class I protein binding GO:0042288 23 13 0,000 0,01311857 0,02390437 ! histone deacetylation GO:0016575 14 13 0,000 0,01311857 0,02389244 ! calcium channel regulator activity GO:0005246 16 13 0,000 0,01311857 0,02388051 ! DNA methylation GO:0006306 15 13 0,000 0,01311857 0,0238686 GO:0006305|DNA alkylation, ! mRNA splice site selection GO:0006376 17 13 0,000 0,01311857 0,0238567 ! chromatin silencing GO:0006342 13 13 0,000 0,01311857 0,02384482 ! serotonin receptor activity GO:0004993 16 13 0,000 0,01311857 0,02383294 ! monosaccharide transmembrane transporter activity GO:0015145 13 13 0,000 0,01311857 0,02382108 ! T cell homeostasis GO:0043029 14 13 0,000 0,01311857 0,02380923 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01311857 0,02379739 ! diacylglycerol kinase activity GO:0004143 15 13 0,000 0,01311857 0,02378556 ! response to gamma radiation GO:0010332 14 13 0,000 0,01311857 0,02377375 ! synaptic transmission, cholinergic GO:0007271 14 13 0,000 0,01311857 0,02376194 ! retinoic acid receptor activity GO:0003708 15 13 0,000 0,01311857 0,02375015 ! purine base metabolic process GO:0006144 15 13 0,000 0,01311857 0,02373837 ! cAMP binding GO:0030552 15 13 0,000 0,01311857 0,0237266 ! biogenic amine catabolic process GO:0042402 14 13 0,000 0,01311857 0,02371484 ! negative regulation of BMP signaling pathway GO:0030514 14 13 0,000 0,01311857 0,0237031 ! regulation of axon extension GO:0030516 16 13 0,000 0,01311857 0,02369136 ! drug transporter activity GO:0015238 14 13 0,000 0,01311857 0,02367964 ! regulation of NF-kappaB import into nucleus GO:0042345 14 13 0,000 0,01311857 0,02366793 ! calcium-activated potassium channel activity GO:0015269 15 13 0,000 0,01311857 0,02365623 ! response to cold GO:0009409 13 13 0,000 0,01311857 0,02364454 ! cadherin binding GO:0045296 16 13 0,000 0,01311857 0,02363286 ! nucleolar part GO:0044452 13 13 0,000 0,01311857 0,0236212 ! tRNA modification GO:0006400 14 14 0,000 0,01412091 0,02541346 ! cis-Golgi network GO:0005801 16 14 0,000 0,01412091 0,02540093 ! negative regulation of hormone secretion GO:0046888 14 14 0,000 0,01412091 0,02538841 ! 'de novo' protein folding GO:0006458 14 14 0,000 0,01412091 0,0253759 ! organellar large ribosomal subunit GO:0000315 15 14 0,000 0,01412091 0,02536341 GO:0005762|mitochondrial large ribosomal subunit, ! phosphoinositide phosphorylation GO:0046854 18 14 0,000 0,01412091 0,02535093 ! peroxisomal transport GO:0043574 14 14 0,000 0,01412091 0,02533846 ! cardiac muscle contraction GO:0060048 15 14 0,000 0,01412091 0,025326 ! dopamine receptor signaling pathway GO:0007212 19 14 0,000 0,01412091 0,02531355 ! mechanoreceptor differentiation GO:0042490 16 14 0,000 0,01412091 0,02530112 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 18 14 0,000 0,01412091 0,0252887 ! pseudouridine synthesis GO:0001522 14 14 0,000 0,01412091 0,02527629 ! caspase activator activity GO:0008656 16 14 0,000 0,01412091 0,02526389 ! MHC class II protein complex GO:0042613 19 14 0,000 0,01412091 0,02525151 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01412091 0,02523914 ! cAMP-dependent protein kinase regulator activity GO:0008603 17 14 0,000 0,01412091 0,02522678 ! cation:cation antiporter activity GO:0015491 14 14 0,000 0,01412091 0,02521443 ! glycoprotein catabolic process GO:0006516 16 14 0,000 0,01412091 0,02520209 ! protein polyubiquitination GO:0000209 15 14 0,000 0,01412091 0,02518977 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 34 14 0,000 0,01412091 0,02517746 ! negative regulation of microtubule depolymerization GO:0007026 16 14 0,000 0,01412091 0,02516516 GO:0031114|regulation of microtubule depolymerization, ! cell-cell junction assembly GO:0007043 15 14 0,000 0,01412091 0,02515287 ! response to vitamin A GO:0033189 18 14 0,000 0,01412091 0,0251406 ! actin filament bundle formation GO:0051017 16 14 0,000 0,01412091 0,02512833 ! regulation of lipoprotein lipase activity GO:0051004 15 14 0,000 0,01412091 0,02511608 ! plasma membrane fusion GO:0045026 15 14 0,000 0,01412091 0,02510384 ! purine nucleoside monophosphate metabolic process GO:0009126 15 14 0,000 0,01412091 0,02509161 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 16 14 0,000 0,01412091 0,0250794 ! presynaptic membrane GO:0042734 14 14 0,000 0,01412091 0,02506719 ! negative regulation of immune response GO:0050777 21 14 0,000 0,01412091 0,025055 ! gastrulation with mouth forming second GO:0001702 15 14 0,000 0,01412091 0,02504282 ! neural crest cell migration GO:0001755 15 14 0,000 0,01412091 0,02503065 ! anaphase-promoting complex GO:0005680 17 14 0,000 0,01412091 0,02501849 ! positive regulation of oxidoreductase activity GO:0051353 14 14 0,000 0,01412091 0,02500635 ! negative regulation of protein secretion GO:0050709 17 14 0,000 0,01412091 0,02499422 ! cofactor transport GO:0051181 16 14 0,000 0,01412091 0,0249821 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,01412091 0,02496999 ! protein-chromophore linkage GO:0018298 16 14 0,000 0,01412091 0,02495789 ! cobalt ion binding GO:0050897 14 14 0,000 0,01412091 0,0249458 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01412091 0,02493373 ! positive regulation of transmission of nerve impulse GO:0051971 16 14 0,000 0,01412091 0,02492166 ! aspartate family amino acid biosynthetic process GO:0009067 17 14 0,000 0,01412091 0,02490961 ! gas transport GO:0015669 15 14 0,000 0,01412091 0,02489757 ! pyridine nucleotide biosynthetic process GO:0019363 15 14 0,000 0,01412091 0,02488555 ! heme biosynthetic process GO:0006783 14 14 0,000 0,01412091 0,02487353 ! insulin secretion GO:0030073 17 14 0,000 0,01412091 0,02486153 ! tRNA binding GO:0000049 16 14 0,000 0,01412091 0,02484953 ! positive regulation of cell killing GO:0031343 16 14 0,000 0,01412091 0,02483755 ! positive regulation of protein complex assembly GO:0031334 14 14 0,000 0,01412091 0,02482558 ! G1 phase of mitotic cell cycle GO:0000080 15 14 0,000 0,01412091 0,02481362 ! phosphatidylinositol metabolic process GO:0046488 15 14 0,000 0,01412091 0,02480168 ! regulation of neuronal synaptic plasticity GO:0048168 24 14 0,000 0,01412091 0,02478974 ! MAP kinase activity GO:0004707 16 14 0,000 0,01412091 0,02477782 ! cytokine biosynthetic process GO:0042089 14 14 0,000 0,01412091 0,0247659 ! mannosyltransferase activity GO:0000030 14 14 0,000 0,01412091 0,024754 ! isoprenoid biosynthetic process GO:0008299 17 14 0,000 0,01412091 0,02474211 ! C-C chemokine binding GO:0019957 15 14 0,000 0,01412091 0,02473024 GO:0016493|C-C chemokine receptor activity, ! cardiac muscle tissue development GO:0048738 16 14 0,000 0,01412091 0,02471837 ! complement activation, alternative pathway GO:0006957 14 14 0,000 0,01412091 0,02470651 ! response to osmotic stress GO:0006970 17 14 0,000 0,01412091 0,02469467 ! fructose metabolic process GO:0006000 15 14 0,000 0,01412091 0,02468284 ! telomeric DNA binding GO:0042162 17 14 0,000 0,01412091 0,02467102 ! monoamine transport GO:0015844 15 14 0,000 0,01412091 0,02465921 ! regulation of pathway-restricted SMAD protein phosphorylation GO:0060393 14 14 0,000 0,01412091 0,02464741 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,01412091 0,02463562 ! dendritic spine GO:0043197 15 14 0,000 0,01412091 0,02462384 ! stem cell development GO:0048864 14 14 0,000 0,01412091 0,02461208 GO:0019827|stem cell maintenance, ! regulation of alpha-beta T cell activation GO:0046634 15 14 0,000 0,01412091 0,02460032 ! regulation of insulin receptor signaling pathway GO:0046626 17 14 0,000 0,01412091 0,02458858 ! regulation of cytokine production during immune response GO:0002718 15 14 0,000 0,01412091 0,02457685 ! positive regulation of protein import into nucleus GO:0042307 16 14 0,000 0,01412091 0,02456513 ! regulation of cellular pH GO:0030641 14 14 0,000 0,01412091 0,02455342 ! regulation of monooxygenase activity GO:0032768 14 14 0,000 0,01412091 0,02454172 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,01412091 0,02453004 ! sarcoplasmic reticulum membrane GO:0033017 16 14 0,000 0,01412091 0,02451836 ! detection of biotic stimulus GO:0009595 16 14 0,000 0,01412091 0,0245067 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 16 14 0,000 0,01412091 0,02449505 ! mannosidase activity GO:0015923 19 14 0,000 0,01412091 0,0244834 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 17 14 0,000 0,01412091 0,02447177 ! negative regulation of tissue remodeling GO:0034104 16 14 0,000 0,01412091 0,02446015 ! positive regulation of bone mineralization GO:0030501 14 14 0,000 0,01412091 0,02444854 ! neuromuscular synaptic transmission GO:0007274 15 14 0,000 0,01412091 0,02443694 ! regulation of immunoglobulin production GO:0002637 15 14 0,000 0,01412091 0,02442536 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,01412091 0,02441378 ! fucosyltransferase activity GO:0008417 16 14 0,000 0,01412091 0,02440222 ! sperm-egg recognition GO:0035036 17 14 0,000 0,01412091 0,02439066 GO:0007339|binding of sperm to zona pellucida, ! defense response to virus GO:0051607 21 14 0,000 0,01412091 0,02437912 ! SWI/SNF-type complex GO:0070603 16 14 0,000 0,01412091 0,02436759 GO:0016514|SWI/SNF complex, ! aldo-keto reductase activity GO:0004033 15 14 0,000 0,01412091 0,02435607 ! positive regulation of translation GO:0045727 17 15 0,000 0,01512228 0,02607093 ! nuclear replication fork GO:0043596 26 15 0,000 0,01512228 0,02605862 ! transferase activity, transferring amino-acyl groups GO:0016755 15 15 0,000 0,01512228 0,02604631 ! 2'-deoxyribonucleotide metabolic process GO:0009394 16 15 0,000 0,01512228 0,02603402 GO:0019692|deoxyribose phosphate metabolic process, ! phospholipid catabolic process GO:0009395 26 15 0,000 0,01512228 0,02602174 ! endothelial cell migration GO:0043542 16 15 0,000 0,01512228 0,02600947 ! lipid phosphorylation GO:0046834 19 15 0,000 0,01512228 0,02599722 ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,01512228 0,02598497 ! response to vitamin GO:0033273 19 15 0,000 0,01512228 0,02597274 ! striated muscle thick filament GO:0005863 16 15 0,000 0,01512228 0,02596051 GO:0032982|myosin filament, ! cellular response to hydrogen peroxide GO:0070301 15 15 0,000 0,01512228 0,0259483 GO:0042744|hydrogen peroxide catabolic process, ! endocrine pancreas development GO:0031018 16 15 0,000 0,01512228 0,0259361 ! regulation of interleukin-2 biosynthetic process GO:0045076 15 15 0,000 0,01512228 0,02592392 ! glutamate metabolic process GO:0006536 17 15 0,000 0,01512228 0,02591174 ! pituitary gland development GO:0021983 16 15 0,000 0,01512228 0,02589957 ! cholesterol binding GO:0015485 15 15 0,000 0,01512228 0,02588742 ! NAD metabolic process GO:0019674 17 15 0,000 0,01512228 0,02587528 ! protease binding GO:0002020 20 15 0,000 0,01512228 0,02586315 ! regulation of heart rate GO:0002027 20 15 0,000 0,01512228 0,02585103 ! actin filament bundle GO:0032432 18 15 0,000 0,01512228 0,02583892 GO:0001725|stress fiber, ! Golgi cisterna GO:0031985 17 15 0,000 0,01512228 0,02582682 ! regulation of exocytosis GO:0017157 16 15 0,000 0,01512228 0,02581474 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,01512228 0,02580266 ! embryonic digit morphogenesis GO:0042733 17 15 0,000 0,01512228 0,0257906 ! positive regulation of biomineral formation GO:0070169 15 15 0,000 0,01512228 0,02577855 ! prostaglandin metabolic process GO:0006693 15 15 0,000 0,01512228 0,02576651 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 20 15 0,000 0,01512228 0,02575448 ! neuron recognition GO:0008038 18 15 0,000 0,01512228 0,02574246 ! filopodium GO:0030175 17 15 0,000 0,01512228 0,02573045 ! negative regulation of blood coagulation GO:0030195 18 15 0,000 0,01512228 0,02571846 ! folic acid and derivative metabolic process GO:0006760 15 15 0,000 0,01512228 0,02570647 ! positive regulation of neuron differentiation GO:0045666 27 15 0,000 0,01512228 0,0256945 ! peptide hormone binding GO:0017046 16 15 0,000 0,01512228 0,02568254 ! regulation of ATPase activity GO:0043462 17 15 0,000 0,01512228 0,02567059 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 16 15 0,000 0,01512228 0,02565865 ! regulation of leukocyte mediated cytotoxicity GO:0001910 21 15 0,000 0,01512228 0,02564672 ! acid-thiol ligase activity GO:0016878 16 15 0,000 0,01512228 0,0256348 ! aromatic compound biosynthetic process GO:0019438 25 15 0,000 0,01512228 0,02562289 ! positive regulation of calcium ion transport GO:0051928 20 15 0,000 0,01512228 0,025611 ! dystrophin-associated glycoprotein complex GO:0016010 17 15 0,000 0,01512228 0,02559911 ! RNA 3'-end processing GO:0031123 16 15 0,000 0,01512228 0,02558724 ! developmental induction GO:0031128 17 15 0,000 0,01512228 0,02557538 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 17 15 0,000 0,01512228 0,02556353 ! regulation of skeletal muscle tissue development GO:0048641 18 15 0,000 0,01512228 0,02555169 ! lactation GO:0007595 17 15 0,000 0,01512228 0,02553986 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 16 15 0,000 0,01512228 0,02552804 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01512228 0,02551623 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,01512228 0,02550443 ! double-strand break repair via homologous recombination GO:0000724 36 15 0,000 0,01512228 0,02549265 GO:0000725|recombinational repair, ! phosphatidylcholine metabolic process GO:0046470 16 15 0,000 0,01512228 0,02548087 ! regulation of cell-cell adhesion GO:0022407 18 15 0,000 0,01512228 0,02546911 ! sulfate transport GO:0008272 16 15 0,000 0,01512228 0,02545736 ! hindlimb morphogenesis GO:0035137 17 15 0,000 0,01512228 0,02544561 ! bile acid metabolic process GO:0008206 17 15 0,000 0,01512228 0,02543388 ! very-low-density lipoprotein particle GO:0034361 16 15 0,000 0,01512228 0,02542216 GO:0034385|triglyceride-rich lipoprotein particle, ! adult walking behavior GO:0007628 19 15 0,000 0,01512228 0,02541045 ! 2 iron, 2 sulfur cluster binding GO:0051537 16 15 0,000 0,01512228 0,02539875 ! heart looping GO:0001947 18 15 0,000 0,01512228 0,02538707 ! protein kinase C activity GO:0004697 17 15 0,000 0,01512228 0,02537539 ! oligodendrocyte differentiation GO:0048709 15 15 0,000 0,01512228 0,02536372 ! regulation of striated muscle contraction GO:0006942 18 15 0,000 0,01512228 0,02535206 ! pigmentation during development GO:0048066 17 15 0,000 0,01512228 0,02534042 ! cytokine metabolic process GO:0042107 15 15 0,000 0,01512228 0,02532878 ! vesicle coating GO:0006901 17 15 0,000 0,01512228 0,02531716 ! disulfide oxidoreductase activity GO:0015036 16 15 0,000 0,01512228 0,02530555 ! neutral amino acid transport GO:0015804 18 15 0,000 0,01512228 0,02529394 ! L-amino acid transport GO:0015807 16 15 0,000 0,01512228 0,02528235 ! microfilament motor activity GO:0000146 15 15 0,000 0,01512228 0,02527077 ! carbonate dehydratase activity GO:0004089 18 15 0,000 0,01512228 0,0252592 ! regulation of vasodilation GO:0042312 25 15 0,000 0,01512228 0,02524764 ! DNA replication initiation GO:0006270 15 15 0,000 0,01512228 0,02523609 ! taste receptor activity GO:0008527 15 15 0,000 0,01512228 0,02522455 ! cellular pigmentation GO:0033059 16 15 0,000 0,01512228 0,02521302 ! voltage-gated chloride channel activity GO:0005247 18 15 0,000 0,01512228 0,0252015 ! voltage-gated sodium channel activity GO:0005248 18 15 0,000 0,01512228 0,02519 ! long-chain fatty acid transport GO:0015909 17 15 0,000 0,01512228 0,0251785 ! positive regulation of neurological system process GO:0031646 18 15 0,000 0,01512228 0,02516701 ! nerve-nerve synaptic transmission GO:0007270 17 15 0,000 0,01512228 0,02515554 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 17 15 0,000 0,01512228 0,02514407 ! ion gated channel activity GO:0022839 17 15 0,000 0,01512228 0,02513262 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 15 15 0,000 0,01512228 0,02512117 ! receptor activator activity GO:0030546 17 15 0,000 0,01512228 0,02510974 ! protein transmembrane transporter activity GO:0008320 16 15 0,000 0,01512228 0,02509831 ! negative regulation of mast cell proliferation GO:0070667 16 15 0,000 0,01512228 0,0250869 GO:0042130|negative regulation of T cell proliferation, ! acylglycerol O-acyltransferase activity GO:0016411 16 15 0,000 0,01512228 0,0250755 ! triacylglycerol lipase activity GO:0004806 16 15 0,000 0,01512228 0,0250641 ! peptide hormone processing GO:0016486 19 15 0,000 0,01512228 0,02505272 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,01512228 0,02504135 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 19 16 0,000 0,01612269 0,02668584 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,01612269 0,02667374 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 18 16 0,000 0,01612269 0,02666165 ! heterophilic cell adhesion GO:0007157 17 16 0,000 0,01612269 0,02664956 ! gamma-aminobutyric acid signaling pathway GO:0007214 17 16 0,000 0,01612269 0,0266375 ! kinesin complex GO:0005871 16 16 0,000 0,01612269 0,02662544 ! photoreceptor cell development GO:0042461 22 16 0,000 0,01612269 0,02661339 GO:0046530|photoreceptor cell differentiation, ! negative regulation of gene expression, epigenetic GO:0045814 16 16 0,000 0,01612269 0,02660135 ! mitotic chromosome condensation GO:0007076 17 16 0,000 0,01612269 0,02658933 ! centrosome cycle GO:0007098 26 16 0,000 0,01612269 0,02657731 ! negative regulation of epithelial cell proliferation GO:0050680 18 16 0,000 0,01612269 0,02656531 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 16 0,000 0,01612269 0,02655331 ! DNA duplex unwinding GO:0032508 17 16 0,000 0,01612269 0,02654133 GO:0032392|DNA geometric change, ! cerebral cortex development GO:0021987 16 16 0,000 0,01612269 0,02652936 ! lysosomal transport GO:0007041 16 16 0,000 0,01612269 0,0265174 ! transforming growth factor beta receptor activity GO:0005024 18 16 0,000 0,01612269 0,02650545 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! rough endoplasmic reticulum GO:0005791 16 16 0,000 0,01612269 0,02649351 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 16 16 0,000 0,01612269 0,02648158 ! small nucleolar ribonucleoprotein complex GO:0005732 16 16 0,000 0,01612269 0,02646966 ! myofibril assembly GO:0030239 17 16 0,000 0,01612269 0,02645776 GO:0055002|striated muscle cell development, ! G1 phase GO:0051318 17 16 0,000 0,01612269 0,02644586 ! receptor signaling complex scaffold activity GO:0030159 19 16 0,000 0,01612269 0,02643397 ! negative regulation of inflammatory response GO:0050728 17 16 0,000 0,01612269 0,0264221 ! clathrin vesicle coat GO:0030125 20 16 0,000 0,01612269 0,02641023 ! endodeoxyribonuclease activity GO:0004520 43 16 0,000 0,01612269 0,02639838 ! sphingolipid catabolic process GO:0030149 18 16 0,000 0,01612269 0,02638654 GO:0046466|membrane lipid catabolic process, ! natural killer cell activation GO:0030101 17 16 0,000 0,01612269 0,0263747 ! steroid catabolic process GO:0006706 18 16 0,000 0,01612269 0,02636288 ! branched chain family amino acid metabolic process GO:0009081 18 16 0,000 0,01612269 0,02635107 ! cell-cell recognition GO:0009988 19 16 0,000 0,01612269 0,02633927 ! somatic diversification of immune receptors GO:0002200 17 16 0,000 0,01612269 0,02632748 ! spleen development GO:0048536 19 16 0,000 0,01612269 0,0263157 ! lymphocyte homeostasis GO:0002260 17 16 0,000 0,01612269 0,02630393 ! regulation of fatty acid oxidation GO:0046320 19 16 0,000 0,01612269 0,02629217 ! neural tube closure GO:0001843 19 16 0,000 0,01612269 0,02628042 GO:0060606|tube closure, ! antigen receptor-mediated signaling pathway GO:0050851 22 16 0,000 0,01612269 0,02626869 ! regulation of glucose metabolic process GO:0010906 18 16 0,000 0,01612269 0,02625696 ! regulation of lipid catabolic process GO:0050994 18 16 0,000 0,01612269 0,02624524 ! viral genome replication GO:0019079 16 16 0,000 0,01612269 0,02623354 ! regulation of neurotransmitter transport GO:0051588 19 16 0,000 0,01612269 0,02622184 ! memory GO:0007613 18 16 0,000 0,01612269 0,02621016 ! regulation of carbohydrate biosynthetic process GO:0043255 17 16 0,000 0,01612269 0,02619848 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01612269 0,02618682 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 18 16 0,000 0,01612269 0,02617516 ! glycoprotein binding GO:0001948 19 16 0,000 0,01612269 0,02616352 ! negative regulation of endothelial cell proliferation GO:0001937 17 16 0,000 0,01612269 0,02615189 ! syntaxin binding GO:0019905 18 16 0,000 0,01612269 0,02614026 ! myosin binding GO:0017022 17 16 0,000 0,01612269 0,02612865 ! epidermis morphogenesis GO:0048730 18 16 0,000 0,01612269 0,02611705 ! fucose metabolic process GO:0006004 18 16 0,000 0,01612269 0,02610545 ! actin polymerization or depolymerization GO:0008154 18 16 0,000 0,01612269 0,02609387 ! membrane budding GO:0006900 18 16 0,000 0,01612269 0,0260823 ! preassembly of GPI anchor in ER membrane GO:0016254 18 16 0,000 0,01612269 0,02607074 ! intermediate filament cytoskeleton organization GO:0045104 16 16 0,000 0,01612269 0,02605919 ! behavioral interaction between organisms GO:0051705 19 16 0,000 0,01612269 0,02604765 ! nucleotide-excision repair, DNA gap filling GO:0006297 19 16 0,000 0,01612269 0,02603612 ! anchored to plasma membrane GO:0046658 20 16 0,000 0,01612269 0,0260246 ! calcium activated cation channel activity GO:0005227 18 16 0,000 0,01612269 0,02601309 ! apoptotic protease activator activity GO:0016505 18 16 0,000 0,01612269 0,02600159 ! sulfuric ester hydrolase activity GO:0008484 18 16 0,000 0,01612269 0,0259901 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 18 16 0,000 0,01612269 0,02597862 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,01612269 0,02596715 ! RNA polymerase II transcription mediator activity GO:0016455 19 16 0,000 0,01612269 0,02595569 ! axoneme GO:0005930 16 16 0,000 0,01612269 0,02594424 ! negative regulation of homeostatic process GO:0032845 19 16 0,000 0,01612269 0,0259328 ! anion exchanger activity GO:0015380 17 17 0,000 0,01712214 0,02752824 ! positive regulation of hormone secretion GO:0046887 19 17 0,000 0,01712214 0,02751611 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 17 17 0,000 0,01712214 0,027504 ! transcription from RNA polymerase III promoter GO:0006383 18 17 0,000 0,01712214 0,02749189 ! glial cell development GO:0021782 17 17 0,000 0,01712214 0,0274798 ! limbic system development GO:0021761 18 17 0,000 0,01712214 0,02746771 ! protein phosphatase type 2A regulator activity GO:0008601 19 17 0,000 0,01712214 0,02745564 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 17 0,000 0,01712214 0,02744357 ! ephrin receptor activity GO:0005003 21 17 0,000 0,01712214 0,02743152 ! acetylcholine receptor activity GO:0015464 18 17 0,000 0,01712214 0,02741948 ! glutamine metabolic process GO:0006541 26 17 0,000 0,01712214 0,02740745 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 21 17 0,000 0,01712214 0,02739543 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 37 17 0,000 0,01712214 0,02738342 ! signal sequence binding GO:0005048 18 17 0,000 0,01712214 0,02737142 ! cell-substrate junction assembly GO:0007044 21 17 0,000 0,01712214 0,02735943 ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,01712214 0,02734745 ! organelle subcompartment GO:0031984 19 17 0,000 0,01712214 0,02733548 ! regulation of vasoconstriction GO:0019229 21 17 0,000 0,01712214 0,02732352 ! membrane depolarization GO:0051899 19 17 0,000 0,01712214 0,02731158 ! oogenesis GO:0048477 20 17 0,000 0,01712214 0,02729964 ! nuclear outer membrane GO:0005640 21 17 0,000 0,01712214 0,02728771 ! regulation of immunoglobulin mediated immune response GO:0002889 18 17 0,000 0,01712214 0,0272758 GO:0002712|regulation of B cell mediated immunity, ! immunoglobulin production GO:0002377 21 17 0,000 0,01712214 0,02726389 GO:0002440|production of molecular mediator of immune response, ! positive regulation of cellular carbohydrate metabolic process GO:0010676 18 17 0,000 0,01712214 0,027252 ! positive regulation of macrophage differentiation GO:0045651 21 17 0,000 0,01712214 0,02724011 ! organic cation transport GO:0015695 17 17 0,000 0,01712214 0,02722824 ! porphyrin biosynthetic process GO:0006779 17 17 0,000 0,01712214 0,02721637 GO:0033014|tetrapyrrole biosynthetic process, ! phosphatidylinositol binding GO:0005545 21 17 0,000 0,01712214 0,02720452 ! hyaluronic acid binding GO:0005540 19 17 0,000 0,01712214 0,02719268 ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 17 0,000 0,01712214 0,02718084 ! negative regulation of coagulation GO:0050819 20 17 0,000 0,01712214 0,02716902 ! cellular monovalent inorganic cation homeostasis GO:0030004 18 17 0,000 0,01712214 0,02715721 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 17 0,000 0,01712214 0,0271454 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 17 0,000 0,01712214 0,02713361 ! negative regulation of defense response GO:0031348 19 17 0,000 0,01712214 0,02712183 ! lipid localization GO:0010876 19 17 0,000 0,01712214 0,02711006 GO:0019915|lipid storage, ! tube lumen formation GO:0035148 20 17 0,000 0,01712214 0,0270983 ! negative regulation of cytokine biosynthetic process GO:0042036 18 17 0,000 0,01712214 0,02708655 ! regulation of systemic arterial blood pressure by hormone GO:0001990 17 17 0,000 0,01712214 0,0270748 GO:0050886|endocrine process, ! MAP kinase kinase kinase activity GO:0004709 19 17 0,000 0,01712214 0,02706307 ! negative regulation of protein amino acid phosphorylation GO:0001933 19 17 0,000 0,01712214 0,02705135 ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 22 17 0,000 0,01712214 0,02703964 ! response to hexose stimulus GO:0009746 20 17 0,000 0,01712214 0,02702794 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! transmembrane receptor protein phosphatase activity GO:0019198 24 17 0,000 0,01712214 0,02701625 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 17 0,000 0,01712214 0,02700457 ! AMP binding GO:0016208 19 17 0,000 0,01712214 0,0269929 ! UDP-galactosyltransferase activity GO:0035250 19 17 0,000 0,01712214 0,02698124 ! receptor metabolic process GO:0043112 20 17 0,000 0,01712214 0,02696959 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 23 17 0,000 0,01712214 0,02695795 ! alcohol binding GO:0043178 20 17 0,000 0,01712214 0,02694632 ! T cell differentiation in the thymus GO:0033077 28 17 0,000 0,01712214 0,0269347 ! visual learning GO:0008542 31 17 0,000 0,01712214 0,02692309 ! structural constituent of eye lens GO:0005212 20 17 0,000 0,01712214 0,02691149 ! cellular amino acid derivative catabolic process GO:0042219 19 17 0,000 0,01712214 0,0268999 ! neutrophil chemotaxis GO:0030593 17 17 0,000 0,01712214 0,02688832 ! protein localization in mitochondrion GO:0070585 19 17 0,000 0,01712214 0,02687675 GO:0006626|protein targeting to mitochondrion, ! aspartic-type endopeptidase activity GO:0004190 18 17 0,000 0,01712214 0,02686519 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 19 17 0,000 0,01712214 0,02685364 ! proton-transporting ATP synthase complex GO:0045259 17 17 0,000 0,01712214 0,0268421 ! translation elongation factor activity GO:0003746 19 17 0,000 0,01712214 0,02683057 ! cilium assembly GO:0042384 18 17 0,000 0,01712214 0,02681905 ! transforming growth factor beta receptor binding GO:0005160 19 17 0,000 0,01712214 0,02680754 ! positive regulation of homeostatic process GO:0032846 23 17 0,000 0,01712214 0,02679604 ! solute:hydrogen antiporter activity GO:0015299 18 17 0,000 0,01712214 0,02678455 ! protein secretion GO:0009306 19 18 0,000 0,01812063 0,02833436 ! positive regulation of ossification GO:0045778 19 18 0,000 0,01812063 0,02832222 ! positive regulation of angiogenesis GO:0045766 19 18 0,000 0,01812063 0,02831009 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,01812063 0,02829797 GO:0005763|mitochondrial small ribosomal subunit, ! protein amino acid deacetylation GO:0006476 19 18 0,000 0,01812063 0,02828586 ! protein amino acid acetylation GO:0006473 21 18 0,000 0,01812063 0,02827376 ! positive regulation of nucleocytoplasmic transport GO:0046824 20 18 0,000 0,01812063 0,02826167 ! cAMP metabolic process GO:0046058 18 18 0,000 0,01812063 0,02824959 ! regulation of muscle cell differentiation GO:0051147 21 18 0,000 0,01812063 0,02823753 ! cornified envelope GO:0001533 22 18 0,000 0,01812063 0,02822547 ! retinoid metabolic process GO:0001523 19 18 0,000 0,01812063 0,02821342 GO:0016101|diterpenoid metabolic process, ! actomyosin GO:0042641 21 18 0,000 0,01812063 0,02820139 ! positive regulation of proteolysis GO:0045862 20 18 0,000 0,01812063 0,02818936 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 18 0,000 0,01812063 0,02817734 ! calcium-dependent protein binding GO:0048306 20 18 0,000 0,01812063 0,02816534 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 18 18 0,000 0,01812063 0,02815334 ! proton-transporting V-type ATPase complex GO:0033176 18 18 0,000 0,01812063 0,02814136 ! pyrimidine ribonucleoside metabolic process GO:0046131 23 18 0,000 0,01812063 0,02812938 ! regulation of ion transmembrane transporter activity GO:0032412 21 18 0,000 0,01812063 0,02811742 ! positive regulation of carbohydrate metabolic process GO:0045913 19 18 0,000 0,01812063 0,02810546 ! primary neural tube formation GO:0014020 21 18 0,000 0,01812063 0,02809352 ! recycling endosome GO:0055037 22 18 0,000 0,01812063 0,02808158 ! muscle cell development GO:0055001 20 18 0,000 0,01812063 0,02806966 ! kinase activator activity GO:0019209 22 18 0,000 0,01812063 0,02805775 ! positive regulation of T cell differentiation GO:0045582 28 18 0,000 0,01812063 0,02804584 ! positive regulation of multicellular organism growth GO:0040018 19 18 0,000 0,01812063 0,02803395 ! somitogenesis GO:0001756 20 18 0,000 0,01812063 0,02802206 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,01812063 0,02801019 ! low-density lipoprotein binding GO:0030169 19 18 0,000 0,01812063 0,02799833 ! positive regulation of cytokine secretion GO:0050715 21 18 0,000 0,01812063 0,02798647 ! negative regulation of intracellular transport GO:0032387 20 18 0,000 0,01812063 0,02797463 ! glutamine family amino acid catabolic process GO:0009065 21 18 0,000 0,01812063 0,0279628 ! basal plasma membrane GO:0009925 21 18 0,000 0,01812063 0,02795097 GO:0045178|basal part of cell, ! vitamin D receptor binding GO:0042809 20 18 0,000 0,01812063 0,02793916 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 19 18 0,000 0,01812063 0,02792736 ! embryonic organ morphogenesis GO:0048562 22 18 0,000 0,01812063 0,02791556 ! regulation of cell killing GO:0031341 24 18 0,000 0,01812063 0,02790378 ! positive regulation of cellular catabolic process GO:0031331 20 18 0,000 0,01812063 0,027892 ! nuclear chromosome, telomeric region GO:0000784 30 18 0,000 0,01812063 0,02788024 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 19 18 0,000 0,01812063 0,02786849 ! intra-Golgi vesicle-mediated transport GO:0006891 20 18 0,000 0,01812063 0,02785674 ! protein complex scaffold GO:0032947 22 18 0,000 0,01812063 0,02784501 ! SNAP receptor activity GO:0005484 21 18 0,000 0,01812063 0,02783328 ! dendrite development GO:0016358 22 18 0,000 0,01812063 0,02782157 ! cell differentiation in spinal cord GO:0021515 21 18 0,000 0,01812063 0,02780987 ! inactivation of MAPK activity GO:0000188 20 18 0,000 0,01812063 0,02779817 ! calmodulin-dependent protein kinase activity GO:0004683 20 18 0,000 0,01812063 0,02778649 ! D-ribose metabolic process GO:0006014 19 18 0,000 0,01812063 0,02777481 ! nuclear ubiquitin ligase complex GO:0000152 31 18 0,000 0,01812063 0,02776315 ! glucuronosyltransferase activity GO:0015020 18 18 0,000 0,01812063 0,02775149 ! coreceptor activity GO:0015026 28 18 0,000 0,01812063 0,02773985 ! response to fungus GO:0009620 18 18 0,000 0,01812063 0,02772821 ! stem cell differentiation GO:0048863 18 18 0,000 0,01812063 0,02771658 ! intermediate filament-based process GO:0045103 18 18 0,000 0,01812063 0,02770497 ! heart process GO:0003015 19 18 0,000 0,01812063 0,02769336 GO:0060047|heart contraction, ! mismatch repair GO:0006298 28 18 0,000 0,01812063 0,02768176 ! vasodilation GO:0042311 20 18 0,000 0,01812063 0,02767018 ! transport vesicle membrane GO:0030658 23 18 0,000 0,01812063 0,0276586 ! MHC protein binding GO:0042287 30 18 0,000 0,01812063 0,02764703 ! inward rectifier potassium channel activity GO:0005242 22 18 0,000 0,01812063 0,02763547 ! chloride transmembrane transporter activity GO:0015108 19 18 0,000 0,01812063 0,02762392 ! bicarbonate transmembrane transporter activity GO:0015106 18 18 0,000 0,01812063 0,02761239 ! ionotropic glutamate receptor activity GO:0004970 22 18 0,000 0,01812063 0,02760086 ! cell-cell adherens junction GO:0005913 20 18 0,000 0,01812063 0,02758934 ! negative regulation of leukocyte proliferation GO:0070664 20 18 0,000 0,01812063 0,02757783 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! ubiquitin-specific protease activity GO:0004843 19 18 0,000 0,01812063 0,02756633 ! ATP-dependent RNA helicase activity GO:0004004 28 18 0,000 0,01812063 0,02755484 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 24 19 0,000 0,01911815 0,02905959 ! pteridine and derivative metabolic process GO:0042558 29 19 0,000 0,01911815 0,02904749 ! proteasome core complex GO:0005839 20 19 0,000 0,01911815 0,0290354 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 22 19 0,000 0,01911815 0,02902331 ! anion:anion antiporter activity GO:0015301 19 19 0,000 0,01911815 0,02901124 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 24 19 0,000 0,01911815 0,02899918 ! regulation of transmembrane transporter activity GO:0022898 22 19 0,000 0,01911815 0,02898712 GO:0032409|regulation of transporter activity, ! regulation of survival gene product expression GO:0045884 23 19 0,000 0,01911815 0,02897508 ! activation of pro-apoptotic gene products GO:0008633 26 19 0,000 0,01911815 0,02896305 ! deoxyribonucleotide metabolic process GO:0009262 20 19 0,000 0,01911815 0,02895103 ! lysosome organization GO:0007040 20 19 0,000 0,01911815 0,02893901 ! cellular macromolecular complex disassembly GO:0034623 23 19 0,000 0,01911815 0,02892701 ! central nervous system neuron development GO:0021954 21 19 0,000 0,01911815 0,02891502 ! threonine-type endopeptidase activity GO:0004298 20 19 0,000 0,01911815 0,02890303 GO:0070003|threonine-type peptidase activity, ! chromosome condensation GO:0030261 20 19 0,000 0,01911815 0,02889106 ! peptidyl-serine phosphorylation GO:0018105 26 19 0,000 0,01911815 0,0288791 ! regulation of endothelial cell migration GO:0010594 22 19 0,000 0,01911815 0,02886714 ! fatty acid beta-oxidation GO:0006635 21 19 0,000 0,01911815 0,0288552 ! peptide cross-linking GO:0018149 23 19 0,000 0,01911815 0,02884327 ! ventricular cardiac muscle morphogenesis GO:0055010 21 19 0,000 0,01911815 0,02883134 ! beta-catenin binding GO:0008013 23 19 0,000 0,01911815 0,02881943 ! positive regulation of locomotion GO:0040017 21 19 0,000 0,01911815 0,02880753 GO:0050921|positive regulation of chemotaxis, ! cell projection membrane GO:0031253 21 19 0,000 0,01911815 0,02879563 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,01911815 0,02878375 ! trans-Golgi network transport vesicle GO:0030140 26 19 0,000 0,01911815 0,02877187 ! sphingolipid biosynthetic process GO:0030148 20 19 0,000 0,01911815 0,02876001 ! vitamin transport GO:0051180 21 19 0,000 0,01911815 0,02874815 ! positive regulation of osteoblast differentiation GO:0045669 22 19 0,000 0,01911815 0,02873631 ! terpenoid metabolic process GO:0006721 20 19 0,000 0,01911815 0,02872447 ! leukotriene biosynthetic process GO:0019370 20 19 0,000 0,01911815 0,02871265 GO:0043450|alkene biosynthetic process, ! nerve development GO:0021675 24 19 0,000 0,01911815 0,02870083 ! retinoid binding GO:0005501 19 19 0,000 0,01911815 0,02868903 GO:0019840|isoprenoid binding, ! regulation of amine transport GO:0051952 23 19 0,000 0,01911815 0,02867723 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 22 19 0,000 0,01911815 0,02866544 ! histone deacetylase activity GO:0004407 20 19 0,000 0,01911815 0,02865367 GO:0033558|protein deacetylase activity, ! regulation of microtubule polymerization or depolymerization GO:0031110 21 19 0,000 0,01911815 0,0286419 ! gluconeogenesis GO:0006094 23 19 0,000 0,01911815 0,02863014 ! post-Golgi vesicle-mediated transport GO:0006892 23 19 0,000 0,01911815 0,02861839 ! microtubule-based transport GO:0010970 20 19 0,000 0,01911815 0,02860665 ! superoxide metabolic process GO:0006801 21 19 0,000 0,01911815 0,02859492 ! C21-steroid hormone metabolic process GO:0008207 20 19 0,000 0,01911815 0,02858321 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,01911815 0,0285715 GO:0006479|protein amino acid methylation, ! L-ascorbic acid binding GO:0031418 19 19 0,000 0,01911815 0,0285598 ! regulation of DNA recombination GO:0000018 38 19 0,000 0,01911815 0,02854811 ! photoreceptor cell maintenance GO:0045494 23 19 0,000 0,01911815 0,02853642 ! positive regulation of cytoskeleton organization GO:0051495 22 19 0,000 0,01911815 0,02852475 ! acetylcholine binding GO:0042166 20 19 0,000 0,01911815 0,02851309 ! heme metabolic process GO:0042168 20 19 0,000 0,01911815 0,02850144 ! SH2 domain binding GO:0042169 25 19 0,000 0,01911815 0,0284898 ! neurotransmitter:sodium symporter activity GO:0005328 21 19 0,000 0,01911815 0,02847816 ! negative regulation of protein catabolic process GO:0042177 19 19 0,000 0,01911815 0,02846654 ! carbohydrate kinase activity GO:0019200 20 19 0,000 0,01911815 0,02845492 ! RNA methyltransferase activity GO:0008173 19 19 0,000 0,01911815 0,02844332 ! RNA-dependent ATPase activity GO:0008186 29 19 0,000 0,01911815 0,02843172 ! body fluid secretion GO:0007589 21 19 0,000 0,01911815 0,02842014 ! neuropeptide hormone activity GO:0005184 25 19 0,000 0,01911815 0,02840856 ! secretory granule membrane GO:0030667 21 19 0,000 0,01911815 0,028397 ! extracellular-glutamate-gated ion channel activity GO:0005234 23 19 0,000 0,01911815 0,02838544 ! ribonucleoprotein binding GO:0043021 20 19 0,000 0,01911815 0,02837389 ! peptidase activator activity GO:0016504 21 19 0,000 0,01911815 0,02836235 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,01911815 0,02835082 ! small conjugating protein-specific protease activity GO:0019783 21 19 0,000 0,01911815 0,0283393 ! regulation of BMP signaling pathway GO:0030510 20 19 0,000 0,01911815 0,02832779 ! sialyltransferase activity GO:0008373 31 19 0,000 0,01911815 0,02831629 ! ATP-dependent DNA helicase activity GO:0004003 30 19 0,000 0,01911815 0,0283048 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 23 20 0,000 0,02011472 0,02976815 ! regulation of anti-apoptosis GO:0045767 20 20 0,000 0,02011472 0,02975608 ! reciprocal meiotic recombination GO:0007131 40 20 0,000 0,02011472 0,02974402 ! protein amino acid ADP-ribosylation GO:0006471 23 20 0,000 0,02011472 0,02973196 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 30 20 0,000 0,02011472 0,02971992 ! retina development in camera-type eye GO:0060041 24 20 0,000 0,02011472 0,02970789 ! negative regulation of lipid metabolic process GO:0045833 34 20 0,000 0,02011472 0,02969587 ! ovarian follicle development GO:0001541 21 20 0,000 0,02011472 0,02968385 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 33 20 0,000 0,02011472 0,02967185 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 21 20 0,000 0,02011472 0,02965986 ! hydrogen peroxide metabolic process GO:0042743 20 20 0,000 0,02011472 0,02964787 ! diencephalon development GO:0021536 22 20 0,000 0,02011472 0,0296359 ! nuclear inner membrane GO:0005637 21 20 0,000 0,02011472 0,02962394 ! regulation of lipid transport GO:0032368 22 20 0,000 0,02011472 0,02961198 ! response to glucocorticoid stimulus GO:0051384 22 20 0,000 0,02011472 0,02960004 ! glutathione metabolic process GO:0006749 21 20 0,000 0,02011472 0,0295881 ! transcriptional repressor complex GO:0017053 23 20 0,000 0,02011472 0,02957617 ! vitamin A metabolic process GO:0006776 20 20 0,000 0,02011472 0,02956426 ! positive regulation of lymphocyte differentiation GO:0045621 30 20 0,000 0,02011472 0,02955235 ! negative regulation of cytokine production GO:0001818 23 20 0,000 0,02011472 0,02954045 ! phosphorus-oxygen lyase activity GO:0016849 21 20 0,000 0,02011472 0,02952857 ! peptide hormone secretion GO:0030072 25 20 0,000 0,02011472 0,02951669 GO:0002790|peptide secretion, ! actin filament-based movement GO:0030048 22 20 0,000 0,02011472 0,02950482 ! Rab GTPase binding GO:0017137 22 20 0,000 0,02011472 0,02949296 ! initiation of viral infection GO:0019059 22 20 0,000 0,02011472 0,02948111 ! voltage-gated anion channel activity GO:0008308 23 20 0,000 0,02011472 0,02946927 ! heterochromatin GO:0000792 20 20 0,000 0,02011472 0,02945744 ! aminoglycan catabolic process GO:0006026 22 20 0,000 0,02011472 0,02944562 ! glycosaminoglycan biosynthetic process GO:0006024 21 20 0,000 0,02011472 0,02943381 ! regulation of chemotaxis GO:0050920 22 20 0,000 0,02011472 0,02942201 ! calcium-independent cell-cell adhesion GO:0016338 27 20 0,000 0,02011472 0,02941022 ! high-density lipoprotein particle GO:0034364 30 20 0,000 0,02011472 0,02939843 ! visual behavior GO:0007632 34 20 0,000 0,02011472 0,02938666 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 23 20 0,000 0,02011472 0,0293749 ! immune response-activating cell surface receptor signaling pathway GO:0002429 27 20 0,000 0,02011472 0,02936314 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of nitric oxide biosynthetic process GO:0045428 21 20 0,000 0,02011472 0,0293514 ! vesicle docking during exocytosis GO:0006904 21 20 0,000 0,02011472 0,02933966 ! nucleotide kinase activity GO:0019201 26 20 0,000 0,02011472 0,02932793 ! rRNA binding GO:0019843 22 20 0,000 0,02011472 0,02931622 ! cytolysis GO:0019835 22 20 0,000 0,02011472 0,02930451 ! renal system process GO:0003014 22 20 0,000 0,02011472 0,02929281 ! specific transcriptional repressor activity GO:0016566 23 20 0,000 0,02011472 0,02928112 ! fatty acid transport GO:0015908 23 20 0,000 0,02011472 0,02926944 ! transaminase activity GO:0008483 22 20 0,000 0,02011472 0,02925777 ! activation of JUN kinase activity GO:0007257 22 20 0,000 0,02011472 0,02924611 ! collagen catabolic process GO:0030574 21 20 0,000 0,02011472 0,02923446 ! microvillus GO:0005902 25 20 0,000 0,02011472 0,02922282 ! tumor necrosis factor receptor binding GO:0005164 22 20 0,000 0,02011472 0,02921118 ! connexon complex GO:0005922 23 20 0,000 0,02011472 0,02919956 ! positive regulation of DNA replication GO:0045740 27 21 0,000 0,02111032 0,03063264 ! positive regulation of protein catabolic process GO:0045732 23 21 0,000 0,02111032 0,03062046 ! translational initiation GO:0006413 21 21 0,000 0,02111032 0,03060829 ! NF-kappaB binding GO:0051059 31 21 0,000 0,02111032 0,03059613 ! heterotrimeric G-protein complex GO:0005834 23 21 0,000 0,02111032 0,03058398 ! positive regulation of bone remodeling GO:0046852 22 21 0,000 0,02111032 0,03057184 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 21 0,000 0,02111032 0,03055971 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! transition metal ion transmembrane transporter activity GO:0046915 25 21 0,000 0,02111032 0,03054758 ! glutathione transferase activity GO:0004364 21 21 0,000 0,02111032 0,03053547 ! voltage-gated calcium channel complex GO:0005891 28 21 0,000 0,02111032 0,03052337 ! glutamate signaling pathway GO:0007215 23 21 0,000 0,02111032 0,03051127 ! regeneration GO:0031099 24 21 0,000 0,02111032 0,03049919 ! MHC class I protein complex GO:0042612 31 21 0,000 0,02111032 0,03048712 ! cellular response to starvation GO:0009267 22 21 0,000 0,02111032 0,03047505 ! peroxisome organization GO:0007031 22 21 0,000 0,02111032 0,030463 ! vacuole organization GO:0007033 23 21 0,000 0,02111032 0,03045095 ! response to lipopolysaccharide GO:0032496 31 21 0,000 0,02111032 0,03043892 ! neural crest cell development GO:0014032 24 21 0,000 0,02111032 0,03042689 GO:0014033|neural crest cell differentiation, ! regulation of protein binding GO:0043393 25 21 0,000 0,02111032 0,03041487 ! nucleobase metabolic process GO:0009112 23 21 0,000 0,02111032 0,03040287 ! regulation of steroid metabolic process GO:0019218 23 21 0,000 0,02111032 0,03039087 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,02111032 0,03037888 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! monocarboxylic acid transmembrane transporter activity GO:0008028 25 21 0,000 0,02111032 0,0303669 ! pallium development GO:0021543 22 21 0,000 0,02111032 0,03035493 ! synaptic vesicle transport GO:0048489 25 21 0,000 0,02111032 0,03034297 ! negative regulation of Wnt receptor signaling pathway GO:0030178 22 21 0,000 0,02111032 0,03033102 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 21 0,000 0,02111032 0,03031908 ! leukocyte homeostasis GO:0001776 22 21 0,000 0,02111032 0,03030715 ! negative regulation of neuron differentiation GO:0045665 22 21 0,000 0,02111032 0,03029522 ! cyclase activity GO:0009975 22 21 0,000 0,02111032 0,03028331 ! aspartate family amino acid metabolic process GO:0009066 24 21 0,000 0,02111032 0,03027141 ! gut development GO:0048565 23 21 0,000 0,02111032 0,03025951 ! calcium-dependent phospholipid binding GO:0005544 22 21 0,000 0,02111032 0,03024763 ! negative regulation of T cell activation GO:0050868 23 21 0,000 0,02111032 0,03023575 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,02111032 0,03022388 ! cortical actin cytoskeleton GO:0030864 21 21 0,000 0,02111032 0,03021203 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,02111032 0,03020018 ! membrane lipid biosynthetic process GO:0046467 22 21 0,000 0,02111032 0,03018834 ! nucleotide-excision repair, DNA damage removal GO:0000718 22 21 0,000 0,02111032 0,03017651 ! axis specification GO:0009798 25 21 0,000 0,02111032 0,03016469 ! response to alkaloid GO:0043279 27 21 0,000 0,02111032 0,03015288 ! 4 iron, 4 sulfur cluster binding GO:0051539 24 21 0,000 0,02111032 0,03014108 ! response to ethanol GO:0045471 28 21 0,000 0,02111032 0,03012929 ! response to carbohydrate stimulus GO:0009743 24 21 0,000 0,02111032 0,0301175 ! smooth muscle contraction GO:0006939 25 21 0,000 0,02111032 0,03010573 ! ubiquitin binding GO:0043130 25 21 0,000 0,02111032 0,03009397 ! vesicle targeting GO:0006903 22 21 0,000 0,02111032 0,03008221 ! phospholipase A2 activity GO:0004623 32 21 0,000 0,02111032 0,03007046 ! SNARE binding GO:0000149 24 21 0,000 0,02111032 0,03005873 ! interaction with host GO:0051701 26 21 0,000 0,02111032 0,030047 ! positive regulation of myeloid leukocyte differentiation GO:0002763 26 21 0,000 0,02111032 0,03003528 ! lymphocyte proliferation GO:0046651 24 21 0,000 0,02111032 0,03002357 ! regulation of tumor necrosis factor production GO:0032680 24 21 0,000 0,02111032 0,03001187 ! regulation of interleukin-2 production GO:0032663 21 21 0,000 0,02111032 0,03000018 ! negative regulation of angiogenesis GO:0016525 23 21 0,000 0,02111032 0,0299885 ! cell-cell junction organization GO:0045216 24 21 0,000 0,02111032 0,02997682 ! single-stranded RNA binding GO:0003727 22 21 0,000 0,02111032 0,02996516 ! cyclic nucleotide binding GO:0030551 25 21 0,000 0,02111032 0,0299535 ! caveola GO:0005901 25 21 0,000 0,02111032 0,02994186 ! water-soluble vitamin biosynthetic process GO:0042364 23 21 0,000 0,02111032 0,02993022 ! insulin receptor binding GO:0005158 25 21 0,000 0,02111032 0,02991859 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,02111032 0,02990697 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,02111032 0,02989536 ! mRNA export from nucleus GO:0006406 26 22 0,000 0,02210497 0,03129178 ! regulation of interferon-gamma production GO:0032649 25 22 0,000 0,02210497 0,03127965 ! hormone secretion GO:0046879 28 22 0,000 0,02210497 0,03126752 ! vesicle docking GO:0048278 24 22 0,000 0,02210497 0,0312554 ! muscle myosin complex GO:0005859 23 22 0,000 0,02210497 0,03124329 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 24 22 0,000 0,02210497 0,03123119 ! actomyosin structure organization GO:0031032 24 22 0,000 0,02210497 0,0312191 ! microtubule organizing center organization GO:0031023 33 22 0,000 0,02210497 0,03120702 GO:0051297|centrosome organization, ! positive regulation of innate immune response GO:0045089 23 22 0,000 0,02210497 0,03119494 ! sperm motility GO:0030317 23 22 0,000 0,02210497 0,03118288 ! potassium channel regulator activity GO:0015459 29 22 0,000 0,02210497 0,03117083 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 24 22 0,000 0,02210497 0,03115878 ! vacuolar transport GO:0007034 22 22 0,000 0,02210497 0,03114675 ! oxidoreductase activity, acting on heme group of donors GO:0016675 23 22 0,000 0,02210497 0,03113472 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! central nervous system neuron differentiation GO:0021953 24 22 0,000 0,02210497 0,03112271 ! cellular response to reactive oxygen species GO:0034614 26 22 0,000 0,02210497 0,0311107 ! purine ribonucleoside metabolic process GO:0046128 24 22 0,000 0,02210497 0,0310987 GO:0042278|purine nucleoside metabolic process, ! G-protein chemoattractant receptor activity GO:0001637 24 22 0,000 0,02210497 0,03108671 GO:0004950|chemokine receptor activity, ! response to corticosteroid stimulus GO:0031960 25 22 0,000 0,02210497 0,03107473 ! PML body GO:0016605 25 22 0,000 0,02210497 0,03106276 ! barbed-end actin filament capping GO:0051016 24 22 0,000 0,02210497 0,0310508 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 27 22 0,000 0,02210497 0,03103885 ! regulation of foam cell differentiation GO:0010743 28 22 0,000 0,02210497 0,03102691 ! cyclic nucleotide biosynthetic process GO:0009190 23 22 0,000 0,02210497 0,03101497 ! leukotriene metabolic process GO:0006691 23 22 0,000 0,02210497 0,03100305 ! glycosphingolipid metabolic process GO:0006687 23 22 0,000 0,02210497 0,03099113 ! deacetylase activity GO:0019213 23 22 0,000 0,02210497 0,03097923 ! pentose metabolic process GO:0019321 23 22 0,000 0,02210497 0,03096733 ! collagen fibril organization GO:0030199 32 22 0,000 0,02210497 0,03095544 ! regulation of response to biotic stimulus GO:0002831 33 22 0,000 0,02210497 0,03094356 ! positive regulation of adaptive immune response GO:0002821 22 22 0,000 0,02210497 0,0309317 ! peptidyl-serine modification GO:0018209 30 22 0,000 0,02210497 0,03091983 ! DNA-directed RNA polymerase complex GO:0000428 23 22 0,000 0,02210497 0,03090798 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 32 22 0,000 0,02210497 0,03089614 ! positive regulation of behavior GO:0048520 24 22 0,000 0,02210497 0,03088431 ! regulation of generation of precursor metabolites and energy GO:0043467 25 22 0,000 0,02210497 0,03087248 ! aromatic compound catabolic process GO:0019439 23 22 0,000 0,02210497 0,03086067 ! embryonic epithelial tube formation GO:0001838 25 22 0,000 0,02210497 0,03084886 GO:0001841|neural tube formation, ! telomere organization GO:0032200 43 22 0,000 0,02210497 0,03083707 GO:0000723|telomere maintenance, ! acetyl-CoA catabolic process GO:0046356 24 22 0,000 0,02210497 0,03082528 GO:0006099|tricarboxylic acid cycle, ! protein tetramerization GO:0051262 25 22 0,000 0,02210497 0,0308135 ! glycerol metabolic process GO:0006071 24 22 0,000 0,02210497 0,03080173 ! cellular component assembly involved in morphogenesis GO:0010927 23 22 0,000 0,02210497 0,03078997 ! cellular iron ion homeostasis GO:0006879 25 22 0,000 0,02210497 0,03077822 ! aminoglycan biosynthetic process GO:0006023 23 22 0,000 0,02210497 0,03076647 ! positive regulation of JAK-STAT cascade GO:0046427 25 22 0,000 0,02210497 0,03075474 ! sterol binding GO:0032934 24 22 0,000 0,02210497 0,03074302 ! calcium-dependent cell-cell adhesion GO:0016339 23 22 0,000 0,02210497 0,0307313 ! digestive system process GO:0022600 25 22 0,000 0,02210497 0,03071959 ! neurotransmitter transporter activity GO:0005326 24 22 0,000 0,02210497 0,03070789 ! organic acid:sodium symporter activity GO:0005343 25 22 0,000 0,02210497 0,0306962 ! nonmotile primary cilium GO:0031513 24 22 0,000 0,02210497 0,03068452 ! negative regulation of myeloid leukocyte differentiation GO:0002762 26 22 0,000 0,02210497 0,03067285 ! base-excision repair GO:0006284 33 22 0,000 0,02210497 0,03066119 ! regulation of chromosome organization GO:0033044 27 22 0,000 0,02210497 0,03064954 ! DNA modification GO:0006304 25 22 0,000 0,02210497 0,03063789 ! detection of chemical stimulus GO:0009593 23 22 0,000 0,02210497 0,03062625 ! positive regulation of tissue remodeling GO:0034105 23 22 0,000 0,02210497 0,03061463 ! GABA-A receptor activity GO:0004890 27 22 0,000 0,02210497 0,03060301 ! response to cytokine stimulus GO:0034097 25 22 0,000 0,02210497 0,0305914 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 24 22 0,000 0,02210497 0,0305798 ! pyrimidine nucleoside metabolic process GO:0006213 27 22 0,000 0,02210497 0,03056821 ! phosphoprotein phosphatase inhibitor activity GO:0004864 25 22 0,000 0,02210497 0,03055662 ! solute:cation antiporter activity GO:0015298 23 22 0,000 0,02210497 0,03054505 ! regulation of transmembrane transport GO:0034762 28 23 0,000 0,02309866 0,03190606 ! protein amino acid O-linked glycosylation GO:0006493 28 23 0,000 0,02309866 0,03189399 ! leukocyte adhesion GO:0007159 26 23 0,000 0,02309866 0,03188192 ! dicarboxylic acid metabolic process GO:0043648 27 23 0,000 0,02309866 0,03186986 ! odontogenesis of dentine-containing tooth GO:0042475 26 23 0,000 0,02309866 0,03185781 ! positive regulation of endocytosis GO:0045807 25 23 0,000 0,02309866 0,03184577 ! mitochondrial membrane organization GO:0007006 25 23 0,000 0,02309866 0,03183374 ! ureteric bud development GO:0001657 24 23 0,000 0,02309866 0,03182172 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 27 23 0,000 0,02309866 0,03180971 ! regulation of insulin secretion GO:0050796 27 23 0,000 0,02309866 0,0317977 ! vitamin biosynthetic process GO:0009110 25 23 0,000 0,02309866 0,03178571 ! negative regulation of neurogenesis GO:0050768 29 23 0,000 0,02309866 0,03177372 ! cholesterol biosynthetic process GO:0006695 29 23 0,000 0,02309866 0,03176174 ! sensory perception of pain GO:0019233 26 23 0,000 0,02309866 0,03174978 ! lipid kinase activity GO:0001727 26 23 0,000 0,02309866 0,03173782 ! platelet activation GO:0030168 27 23 0,000 0,02309866 0,03172587 ! proteoglycan biosynthetic process GO:0030166 24 23 0,000 0,02309866 0,03171393 ! positive regulation of intracellular transport GO:0032388 26 23 0,000 0,02309866 0,031702 ! regulation of blood coagulation GO:0030193 26 23 0,000 0,02309866 0,03169007 ! regulation of cytokine secretion GO:0050707 27 23 0,000 0,02309866 0,03167816 ! fat-soluble vitamin metabolic process GO:0006775 23 23 0,000 0,02309866 0,03166626 ! cellular alkene metabolic process GO:0043449 24 23 0,000 0,02309866 0,03165436 ! aromatic amino acid family metabolic process GO:0009072 25 23 0,000 0,02309866 0,03164247 ! cell surface binding GO:0043498 28 23 0,000 0,02309866 0,0316306 ! porphyrin metabolic process GO:0006778 24 23 0,000 0,02309866 0,03161873 GO:0033013|tetrapyrrole metabolic process, ! ligase activity, forming carbon-sulfur bonds GO:0016877 24 23 0,000 0,02309866 0,03160687 ! regulation of glucose import GO:0046324 28 23 0,000 0,02309866 0,03159502 ! insulin-like growth factor binding GO:0005520 27 23 0,000 0,02309866 0,03158317 ! alditol metabolic process GO:0019400 25 23 0,000 0,02309866 0,03157134 ! positive regulation of JUN kinase activity GO:0043507 25 23 0,000 0,02309866 0,03155952 ! pyruvate metabolic process GO:0006090 27 23 0,000 0,02309866 0,0315477 ! zinc ion transport GO:0006829 26 23 0,000 0,02309866 0,03153589 ! N-acetylglucosamine metabolic process GO:0006044 26 23 0,000 0,02309866 0,0315241 ! antigen processing and presentation of peptide antigen GO:0048002 30 23 0,000 0,02309866 0,03151231 ! sex determination GO:0007530 25 23 0,000 0,02309866 0,03150053 ! phosphate binding GO:0042301 25 23 0,000 0,02309866 0,03148876 ! positive regulation of leukocyte mediated immunity GO:0002705 24 23 0,000 0,02309866 0,03147699 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of interleukin-6 production GO:0032675 26 23 0,000 0,02309866 0,03146524 ! nuclear-transcribed mRNA catabolic process GO:0000956 26 23 0,000 0,02309866 0,03145349 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 28 23 0,000 0,02309866 0,03144176 ! ubiquitin protein ligase binding GO:0031625 24 23 0,000 0,02309866 0,03143003 ! positive regulation of nuclear division GO:0051785 35 23 0,000 0,02309866 0,03141831 GO:0045840|positive regulation of mitosis, ! synaptogenesis GO:0007416 25 23 0,000 0,02309866 0,0314066 ! regulation of bone mineralization GO:0030500 23 23 0,000 0,02309866 0,0313949 ! neurotransmitter secretion GO:0007269 26 23 0,000 0,02309866 0,03138321 ! ethanolamine and derivative metabolic process GO:0042439 34 23 0,000 0,02309866 0,03137152 ! leukocyte proliferation GO:0070661 26 23 0,000 0,02309866 0,03135985 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 24 23 0,000 0,02309866 0,03134818 ! growth cone GO:0030426 27 24 0,000 0,02409139 0,0326833 ! oligosaccharide metabolic process GO:0009311 29 24 0,000 0,02409139 0,03267115 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,02409139 0,03265901 ! pancreas development GO:0031016 27 24 0,000 0,02409139 0,03264688 ! calcium channel complex GO:0034704 31 24 0,000 0,02409139 0,03263476 ! coenzyme catabolic process GO:0009109 26 24 0,000 0,02409139 0,03262264 ! negative regulation of cell development GO:0010721 30 24 0,000 0,02409139 0,03261054 ! cardiac muscle tissue morphogenesis GO:0055008 27 24 0,000 0,02409139 0,03259844 GO:0060415|muscle tissue morphogenesis, ! phosphatase inhibitor activity GO:0019212 27 24 0,000 0,02409139 0,03258635 ! regulation of oxidoreductase activity GO:0051341 24 24 0,000 0,02409139 0,03257428 ! RNA splicing factor activity, transesterification mechanism GO:0031202 25 24 0,000 0,02409139 0,03256221 ! Rho GTPase binding GO:0017048 36 24 0,000 0,02409139 0,03255015 ! regulation of glucose transport GO:0010827 29 24 0,000 0,02409139 0,0325381 ! serine family amino acid metabolic process GO:0009069 27 24 0,000 0,02409139 0,03252605 ! intramolecular transferase activity GO:0016866 26 24 0,000 0,02409139 0,03251402 ! phosphoinositide phospholipase C activity GO:0004435 28 24 0,000 0,02409139 0,032502 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! Z disc GO:0030018 27 24 0,000 0,02409139 0,03248998 ! protein stabilization GO:0050821 24 24 0,000 0,02409139 0,03247797 ! protein import into nucleus, translocation GO:0000060 27 24 0,000 0,02409139 0,03246598 ! embryonic pattern specification GO:0009880 29 24 0,000 0,02409139 0,03245399 ! negative regulation of actin filament depolymerization GO:0030835 26 24 0,000 0,02409139 0,03244201 ! RNA polymerase complex GO:0030880 25 24 0,000 0,02409139 0,03243004 ! cellular polysaccharide biosynthetic process GO:0033692 24 24 0,000 0,02409139 0,03241807 ! glucosamine metabolic process GO:0006041 27 24 0,000 0,02409139 0,03240612 ! small conjugating protein binding GO:0032182 29 24 0,000 0,02409139 0,03239418 ! regulation of transcription factor import into nucleus GO:0042990 26 24 0,000 0,02409139 0,03238224 ! chemokine binding GO:0019956 26 24 0,000 0,02409139 0,03237031 ! catechol metabolic process GO:0009712 29 24 0,000 0,02409139 0,03235839 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of smooth muscle contraction GO:0006940 28 24 0,000 0,02409139 0,03234648 ! NAD+ ADP-ribosyltransferase activity GO:0003950 26 24 0,000 0,02409139 0,03233458 ! multicellular organismal response to stress GO:0033555 27 24 0,000 0,02409139 0,03232269 ! cell aging GO:0007569 47 24 0,000 0,02409139 0,03231081 ! immune response-activating signal transduction GO:0002757 31 24 0,000 0,02409139 0,03229893 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 24 0,000 0,02409139 0,03228707 ! fibroblast growth factor receptor signaling pathway GO:0008543 27 24 0,000 0,02409139 0,03227521 ! voltage-gated calcium channel activity GO:0005245 31 24 0,000 0,02409139 0,03226336 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 29 24 0,000 0,02409139 0,03225152 ! caspase regulator activity GO:0043028 26 24 0,000 0,02409139 0,03223969 ! 3'-5' exonuclease activity GO:0008408 43 24 0,000 0,02409139 0,03222787 ! small nuclear ribonucleoprotein complex GO:0030532 24 24 0,000 0,02409139 0,03221605 ! selenium binding GO:0008430 24 24 0,000 0,02409139 0,03220425 ! spindle pole GO:0000922 35 24 0,000 0,02409139 0,03219245 ! Rho GTPase activator activity GO:0005100 28 24 0,000 0,02409139 0,03218067 ! site of polarized growth GO:0030427 28 25 0,000 0,02508317 0,03349319 ! phenol metabolic process GO:0018958 31 25 0,000 0,02508317 0,03348094 ! regulation of lipid biosynthetic process GO:0046890 35 25 0,000 0,02508317 0,03346869 ! protein amino acid acylation GO:0043543 28 25 0,000 0,02508317 0,03345645 ! aromatase activity GO:0070330 28 25 0,000 0,02508317 0,03344423 ! cholesterol homeostasis GO:0042632 27 25 0,000 0,02508317 0,03343201 GO:0055092|sterol homeostasis, ! positive regulation of epithelial cell proliferation GO:0050679 29 25 0,000 0,02508317 0,0334198 ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 29 25 0,000 0,02508317 0,03340759 ! response to starvation GO:0042594 26 25 0,000 0,02508317 0,0333954 ! dynein complex GO:0030286 28 25 0,000 0,02508317 0,03338322 ! regulation of behavior GO:0050795 27 25 0,000 0,02508317 0,03337104 ! regulation of biomineral formation GO:0070167 25 25 0,000 0,02508317 0,03335888 ! hexose biosynthetic process GO:0019319 31 25 0,000 0,02508317 0,03334672 ! group transfer coenzyme metabolic process GO:0006752 25 25 0,000 0,02508317 0,03333457 ! hormone transport GO:0009914 31 25 0,000 0,02508317 0,03332243 ! response to molecule of bacterial origin GO:0002237 35 25 0,000 0,02508317 0,0333103 ! cell adhesion molecule binding GO:0050839 29 25 0,000 0,02508317 0,03329818 ! regulation of coagulation GO:0050818 28 25 0,000 0,02508317 0,03328607 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,02508317 0,03327396 ! myeloid leukocyte differentiation GO:0002573 28 25 0,000 0,02508317 0,03326187 ! acetyl-CoA metabolic process GO:0006084 27 25 0,000 0,02508317 0,03324978 ! chromosome, telomeric region GO:0000781 38 25 0,000 0,02508317 0,0332377 ! molting cycle process GO:0022404 28 25 0,000 0,02508317 0,03322564 GO:0022405|hair cycle process, GO:0001942|hair follicle development, ! collagen metabolic process GO:0032963 26 25 0,000 0,02508317 0,03321358 ! xenobiotic metabolic process GO:0006805 27 25 0,000 0,02508317 0,03320152 ! phototransduction GO:0007602 27 25 0,000 0,02508317 0,03318948 ! negative regulation of response to external stimulus GO:0032102 30 25 0,000 0,02508317 0,03317745 ! regulation of endothelial cell proliferation GO:0001936 29 25 0,000 0,02508317 0,03316542 ! protein phosphatase binding GO:0019903 27 25 0,000 0,02508317 0,03315341 ! negative regulation of DNA replication GO:0008156 31 25 0,000 0,02508317 0,0331414 ! multicellular organismal catabolic process GO:0044243 27 25 0,000 0,02508317 0,0331294 ! autophagy GO:0006914 28 25 0,000 0,02508317 0,03311741 ! steroid dehydrogenase activity GO:0016229 27 25 0,000 0,02508317 0,03310543 ! response to ionizing radiation GO:0010212 37 25 0,000 0,02508317 0,03309345 ! DNA-directed DNA polymerase activity GO:0003887 30 25 0,000 0,02508317 0,03308149 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 31 26 0,000 0,02607399 0,03437583 ! epidermal growth factor receptor signaling pathway GO:0007173 32 26 0,000 0,02607399 0,03436341 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 29 26 0,000 0,02607399 0,034351 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 26 0,000 0,02607399 0,0343386 ! positive regulation of lipid metabolic process GO:0045834 27 26 0,000 0,02607399 0,03432621 ! hair cycle GO:0042633 29 26 0,000 0,02607399 0,03431382 GO:0042303|molting cycle, ! thyroid hormone receptor binding GO:0046966 30 26 0,000 0,02607399 0,03430145 ! polysaccharide catabolic process GO:0000272 39 26 0,000 0,02607399 0,03428908 ! peptidyl-tyrosine phosphorylation GO:0018108 30 26 0,000 0,02607399 0,03427673 ! early endosome membrane GO:0031901 31 26 0,000 0,02607399 0,03426438 ! negative regulation of protein kinase cascade GO:0010741 40 26 0,000 0,02607399 0,03425204 ! iron ion homeostasis GO:0055072 29 26 0,000 0,02607399 0,03423971 ! glycolipid metabolic process GO:0006664 36 26 0,000 0,02607399 0,03422739 ! GABA receptor activity GO:0016917 31 26 0,000 0,02607399 0,03421508 ! PDZ domain binding GO:0030165 28 26 0,000 0,02607399 0,03420278 ! positive regulation of protein secretion GO:0050714 29 26 0,000 0,02607399 0,03419048 ! regulation of cellular carbohydrate metabolic process GO:0010675 29 26 0,000 0,02607399 0,0341782 ! AP-type membrane coat adaptor complex GO:0030119 30 26 0,000 0,02607399 0,03416592 GO:0030131|clathrin adaptor complex, ! neuromuscular process controlling balance GO:0050885 32 26 0,000 0,02607399 0,03415365 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 45 26 0,000 0,02607399 0,03414139 ! fatty acid binding GO:0005504 28 26 0,000 0,02607399 0,03412914 ! blastocyst development GO:0001824 27 26 0,000 0,02607399 0,0341169 ! regulation of JUN kinase activity GO:0043506 28 26 0,000 0,02607399 0,03410467 ! lysine N-acetyltransferase activity GO:0004468 29 26 0,000 0,02607399 0,03409244 GO:0004402|histone acetyltransferase activity, ! negative regulation of protein polymerization GO:0032272 37 26 0,000 0,02607399 0,03408023 ! regulation of smooth muscle cell proliferation GO:0048660 30 26 0,000 0,02607399 0,03406802 ! regulation of actin filament depolymerization GO:0030834 28 26 0,000 0,02607399 0,03405583 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,02607399 0,03404364 ! iron ion transport GO:0006826 33 26 0,000 0,02607399 0,03403146 ! regulation of synaptic plasticity GO:0048167 36 26 0,000 0,02607399 0,03401928 ! glucose transport GO:0015758 27 26 0,000 0,02607399 0,03400712 ! insulin receptor signaling pathway GO:0008286 34 26 0,000 0,02607399 0,03399497 ! spinal cord development GO:0021510 30 26 0,000 0,02607399 0,03398282 ! histone deacetylase complex GO:0000118 29 26 0,000 0,02607399 0,03397069 ! regulation of peptide secretion GO:0002791 30 26 0,000 0,02607399 0,03395856 ! regulation of production of molecular mediator of immune response GO:0002700 27 26 0,000 0,02607399 0,03394644 ! RNA helicase activity GO:0003724 46 26 0,000 0,02607399 0,03393433 ! brush border GO:0005903 30 26 0,000 0,02607399 0,03392223 ! gap junction GO:0005921 29 26 0,000 0,02607399 0,03391013 ! anion:cation symporter activity GO:0015296 29 26 0,000 0,02607399 0,03389805 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 39 27 0,000 0,02706386 0,03517241 ! mRNA catabolic process GO:0006402 31 27 0,000 0,02706386 0,03515989 ! myelination GO:0042552 31 27 0,000 0,02706386 0,03514737 ! trans-Golgi network GO:0005802 31 27 0,000 0,02706386 0,03513486 ! transferase activity, transferring nitrogenous groups GO:0016769 29 27 0,000 0,02706386 0,03512236 ! spliceosomal snRNP biogenesis GO:0000387 29 27 0,000 0,02706386 0,03510987 ! solute:solute antiporter activity GO:0015300 28 27 0,000 0,02706386 0,03509739 ! vasculogenesis GO:0001570 32 27 0,000 0,02706386 0,03508492 ! hexose transport GO:0008645 28 27 0,000 0,02706386 0,03507245 GO:0015749|monosaccharide transport, ! regulation of innate immune response GO:0045088 28 27 0,000 0,02706386 0,03506 ! cellular response to oxidative stress GO:0034599 32 27 0,000 0,02706386 0,03504755 ! response to organic cyclic substance GO:0014070 34 27 0,000 0,02706386 0,03503512 ! cell fate determination GO:0001709 29 27 0,000 0,02706386 0,03502269 ! lipid oxidation GO:0034440 29 27 0,000 0,02706386 0,03501027 GO:0019395|fatty acid oxidation, ! fatty acid catabolic process GO:0009062 31 27 0,000 0,02706386 0,03499786 ! collagen binding GO:0005518 29 27 0,000 0,02706386 0,03498546 ! carboxy-lyase activity GO:0016831 27 27 0,000 0,02706386 0,03497306 ! phospholipid transporter activity GO:0005548 30 27 0,000 0,02706386 0,03496068 ! liver development GO:0001889 33 27 0,000 0,02706386 0,0349483 ! mitotic sister chromatid segregation GO:0000070 46 27 0,000 0,02706386 0,03493594 ! determination of bilateral symmetry GO:0009855 32 27 0,000 0,02706386 0,03492358 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! integrin complex GO:0008305 30 27 0,000 0,02706386 0,03491123 ! membrane docking GO:0022406 29 27 0,000 0,02706386 0,03489889 ! detection of light stimulus involved in sensory perception GO:0050962 29 27 0,000 0,02706386 0,03488656 GO:0050908|detection of light stimulus involved in visual perception, ! multicellular organismal macromolecule metabolic process GO:0044259 28 27 0,000 0,02706386 0,03487423 ! respiratory gaseous exchange GO:0007585 30 27 0,000 0,02706386 0,03486192 ! phospholipid transport GO:0015914 29 27 0,000 0,02706386 0,03484961 ! sarcoplasmic reticulum GO:0016529 29 27 0,000 0,02706386 0,03483732 ! aminopeptidase activity GO:0004177 33 27 0,000 0,02706386 0,03482503 ! cellular response to nutrient levels GO:0031669 28 27 0,000 0,02706386 0,03481275 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 33 27 0,000 0,02706386 0,03480048 ! biogenic amine biosynthetic process GO:0042401 29 27 0,000 0,02706386 0,03478822 ! negative regulation of transcription regulator activity GO:0090048 32 27 0,000 0,02706386 0,03477596 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 29 27 0,000 0,02706386 0,03476372 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 31 28 0,000 0,02805277 0,0360213 ! Golgi stack GO:0005795 30 28 0,000 0,02805277 0,03600863 ! male gonad development GO:0008584 32 28 0,000 0,02805277 0,03599596 ! regulation of fatty acid metabolic process GO:0019217 41 28 0,000 0,02805277 0,03598331 ! lipoprotein binding GO:0008034 31 28 0,000 0,02805277 0,03597066 ! mesoderm formation GO:0001707 34 28 0,000 0,02805277 0,03595802 ! negative regulation of MAP kinase activity GO:0043407 30 28 0,000 0,02805277 0,03594539 ! peptidyl-tyrosine modification GO:0018212 32 28 0,000 0,02805277 0,03593277 ! deoxyribonuclease activity GO:0004536 56 28 0,000 0,02805277 0,03592015 ! nicotinamide metabolic process GO:0006769 32 28 0,000 0,02805277 0,03590755 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 31 28 0,000 0,02805277 0,03589496 ! regulation of osteoblast differentiation GO:0045667 33 28 0,000 0,02805277 0,03588237 ! negative regulation of neuron apoptosis GO:0043524 39 28 0,000 0,02805277 0,03586979 ! tissue homeostasis GO:0001894 31 28 0,000 0,02805277 0,03585722 GO:0048871|multicellular organismal homeostasis, ! DNA damage checkpoint GO:0000077 48 28 0,000 0,02805277 0,03584467 ! negative regulation of protein complex assembly GO:0031333 39 28 0,000 0,02805277 0,03583211 ! regulation of carbohydrate metabolic process GO:0006109 31 28 0,000 0,02805277 0,03581957 ! sister chromatid segregation GO:0000819 49 28 0,000 0,02805277 0,03580704 ! post-embryonic development GO:0009791 32 28 0,000 0,02805277 0,03579452 ! complement activation, classical pathway GO:0006958 33 28 0,000 0,02805277 0,035782 ! detection of visible light GO:0009584 30 28 0,000 0,02805277 0,03576949 ! calcium-mediated signaling GO:0019722 30 28 0,000 0,02805277 0,035757 ! receptor regulator activity GO:0030545 31 28 0,000 0,02805277 0,03574451 ! acetylgalactosaminyltransferase activity GO:0008376 33 28 0,000 0,02805277 0,03573203 ! symbiosis, encompassing mutualism through parasitism GO:0044403 33 28 0,000 0,02805277 0,03571955 ! response to xenobiotic stimulus GO:0009410 31 28 0,000 0,02805277 0,03570709 ! response to hydrogen peroxide GO:0042542 32 29 0,000 0,02904074 0,03695173 ! hormone binding GO:0042562 31 29 0,000 0,02904074 0,03693885 ! establishment or maintenance of cell polarity GO:0007163 34 29 0,000 0,02904074 0,03692597 ! striated muscle cell differentiation GO:0051146 42 29 0,000 0,02904074 0,0369131 ! NADP or NADPH binding GO:0050661 33 29 0,000 0,02904074 0,03690025 ! nucleotide receptor activity, G-protein coupled GO:0001608 31 29 0,000 0,02904074 0,0368874 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! erythrocyte differentiation GO:0030218 35 29 0,000 0,02904074 0,03687456 ! ceramide metabolic process GO:0006672 29 29 0,000 0,02904074 0,03686173 ! replication fork GO:0005657 42 29 0,000 0,02904074 0,03684891 ! camera-type eye morphogenesis GO:0048593 36 29 0,000 0,02904074 0,03683609 ! monosaccharide biosynthetic process GO:0046364 35 29 0,000 0,02904074 0,03682329 ! negative regulation of lymphocyte activation GO:0051250 32 29 0,000 0,02904074 0,0368105 ! alkaloid metabolic process GO:0009820 33 29 0,000 0,02904074 0,03679771 ! icosanoid biosynthetic process GO:0046456 30 29 0,000 0,02904074 0,03678493 ! regulation of pH GO:0006885 30 29 0,000 0,02904074 0,03677217 ! amino sugar metabolic process GO:0006040 41 29 0,000 0,02904074 0,03675941 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 34 29 0,000 0,02904074 0,03674666 ! phospholipase C activity GO:0004629 43 29 0,000 0,02904074 0,03673391 ! response to mechanical stimulus GO:0009612 33 29 0,000 0,02904074 0,03672118 ! clathrin coated vesicle membrane GO:0030665 33 29 0,000 0,02904074 0,03670846 ! sodium channel activity GO:0005272 33 29 0,000 0,02904074 0,03669574 ! sarcoplasm GO:0016528 31 29 0,000 0,02904074 0,03668304 ! detection of light stimulus GO:0009583 31 29 0,000 0,02904074 0,03667034 ! spermatid development GO:0007286 30 29 0,000 0,02904074 0,03665765 ! DNA polymerase activity GO:0034061 34 29 0,000 0,02904074 0,03664497 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 31 29 0,000 0,02904074 0,0366323 ! sarcolemma GO:0042383 30 29 0,000 0,02904074 0,03661964 ! tumor necrosis factor receptor superfamily binding GO:0032813 31 29 0,000 0,02904074 0,03660698 ! galactosyltransferase activity GO:0008378 33 29 0,000 0,02904074 0,03659434 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,02904074 0,0365817 ! transforming growth factor beta receptor signaling pathway GO:0007179 34 30 0,000 0,03002775 0,03781195 ! mitochondrial nucleoid GO:0042645 44 30 0,000 0,03002775 0,0377989 GO:0009295|nucleoid, ! cholesterol transport GO:0030301 33 30 0,000 0,03002775 0,03778587 GO:0015918|sterol transport, ! histone-lysine N-methyltransferase activity GO:0018024 34 30 0,000 0,03002775 0,03777284 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! cellular carbohydrate biosynthetic process GO:0034637 30 30 0,000 0,03002775 0,03775982 ! scavenger receptor activity GO:0005044 39 30 0,000 0,03002775 0,0377468 ! spliceosome assembly GO:0000245 34 30 0,000 0,03002775 0,0377338 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 39 30 0,000 0,03002775 0,03772081 GO:0004601|peroxidase activity, ! mesoderm morphogenesis GO:0048332 37 30 0,000 0,03002775 0,03770782 ! metanephros development GO:0001656 31 30 0,000 0,03002775 0,03769485 ! glutamate receptor activity GO:0008066 35 30 0,000 0,03002775 0,03768188 ! cyclic nucleotide metabolic process GO:0009187 31 30 0,000 0,03002775 0,03766892 ! positive regulation of MAPKKK cascade GO:0043410 36 30 0,000 0,03002775 0,03765597 ! regulation of macrophage differentiation GO:0045649 37 30 0,000 0,03002775 0,03764303 ! positive regulation of myeloid cell differentiation GO:0045639 37 30 0,000 0,03002775 0,0376301 ! negative regulation of myeloid cell differentiation GO:0045638 35 30 0,000 0,03002775 0,03761718 ! cis-trans isomerase activity GO:0016859 32 30 0,000 0,03002775 0,03760427 ! myeloid leukocyte activation GO:0002274 36 30 0,000 0,03002775 0,03759136 ! negative regulation of protein transport GO:0051224 34 30 0,000 0,03002775 0,03757846 ! cortical cytoskeleton GO:0030863 33 30 0,000 0,03002775 0,03756558 ! protein-lipid complex GO:0032994 41 30 0,000 0,03002775 0,0375527 GO:0034358|plasma lipoprotein particle, ! circadian rhythm GO:0007623 37 30 0,000 0,03002775 0,03753983 ! phosphatase binding GO:0019902 34 30 0,000 0,03002775 0,03752697 ! acute-phase response GO:0006953 44 30 0,000 0,03002775 0,03751412 ! segmentation GO:0035282 37 30 0,000 0,03002775 0,03750128 ! response to toxin GO:0009636 33 30 0,000 0,03002775 0,03748844 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,03002775 0,03747562 ! antigen binding GO:0003823 33 30 0,000 0,03002775 0,0374628 ! regulation of systemic arterial blood pressure GO:0003073 33 30 0,000 0,03002775 0,03744999 ! Golgi-associated vesicle membrane GO:0030660 37 30 0,000 0,03002775 0,03743719 ! ensheathment of neurons GO:0007272 35 30 0,000 0,03002775 0,0374244 GO:0008366|axon ensheathment, ! JAK-STAT cascade GO:0007259 43 30 0,000 0,03002775 0,03741162 ! vesicle localization GO:0051648 31 30 0,000 0,03002775 0,03739885 ! negative regulation of cell adhesion GO:0007162 34 31 0,000 0,03101381 0,03861378 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,03101381 0,03860061 ! acrosomal vesicle GO:0001669 34 31 0,000 0,03101381 0,03858744 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,03101381 0,03857428 ! protein targeting to membrane GO:0006612 35 31 0,000 0,03101381 0,03856114 ! regulation of axonogenesis GO:0050770 37 31 0,000 0,03101381 0,038548 ! regulation of T cell differentiation GO:0045580 43 31 0,000 0,03101381 0,03853487 ! formation of primary germ layer GO:0001704 37 31 0,000 0,03101381 0,03852175 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 33 31 0,000 0,03101381 0,03850864 ! endocytic vesicle GO:0030139 33 31 0,000 0,03101381 0,03849553 ! pyridine nucleotide metabolic process GO:0019362 35 31 0,000 0,03101381 0,03848244 ! spermatid differentiation GO:0048515 32 31 0,000 0,03101381 0,03846936 ! negative regulation of catabolic process GO:0009895 34 31 0,000 0,03101381 0,03845628 ! neuron fate commitment GO:0048663 44 31 0,000 0,03101381 0,03844321 ! regulation of cellular catabolic process GO:0031329 35 31 0,000 0,03101381 0,03843015 ! regulation of JAK-STAT cascade GO:0046425 37 31 0,000 0,03101381 0,0384171 ! morphogenesis of embryonic epithelium GO:0016331 36 31 0,000 0,03101381 0,03840406 ! macromolecular complex disassembly GO:0032984 37 31 0,000 0,03101381 0,03839103 ! cell junction assembly GO:0034329 36 31 0,000 0,03101381 0,03837801 ! drug binding GO:0008144 34 31 0,000 0,03101381 0,038365 ! positive regulation of T cell proliferation GO:0042102 38 31 0,000 0,03101381 0,03835199 ! peptide transport GO:0015833 36 31 0,000 0,03101381 0,03833899 ! DNA integrity checkpoint GO:0031570 51 31 0,000 0,03101381 0,03832601 ! peripheral nervous system development GO:0007422 35 31 0,000 0,03101381 0,03831303 ! I band GO:0031674 34 31 0,000 0,03101381 0,03830006 ! BMP signaling pathway GO:0030509 33 31 0,000 0,03101381 0,0382871 ! adult locomotory behavior GO:0008344 37 31 0,000 0,03101381 0,03827415 ! negative regulation of adenylate cyclase activity GO:0007194 39 32 0,000 0,03199892 0,03947652 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of secretion GO:0051048 37 32 0,000 0,03199892 0,03946317 ! negative regulation of DNA metabolic process GO:0051053 38 32 0,000 0,03199892 0,03944983 ! phosphotransferase activity, phosphate group as acceptor GO:0016776 49 32 0,000 0,03199892 0,03943651 ! meiosis I GO:0007127 53 32 0,000 0,03199892 0,03942319 ! GPI anchor biosynthetic process GO:0006506 35 32 0,000 0,03199892 0,03940988 GO:0006505|GPI anchor metabolic process, ! unsaturated fatty acid biosynthetic process GO:0006636 33 32 0,000 0,03199892 0,03939658 ! sterol biosynthetic process GO:0016126 40 32 0,000 0,03199892 0,03938329 ! vesicle coat GO:0030120 39 32 0,000 0,03199892 0,03937 ! cytokine production GO:0001816 32 32 0,000 0,03199892 0,03935673 ! regulation of calcium ion transport GO:0051924 37 32 0,000 0,03199892 0,03934346 ! proteoglycan metabolic process GO:0006029 34 32 0,000 0,03199892 0,03933021 ! sphingoid metabolic process GO:0046519 33 32 0,000 0,03199892 0,03931696 ! multicellular organismal metabolic process GO:0044236 35 32 0,000 0,03199892 0,03930372 ! oxygen binding GO:0019825 33 32 0,000 0,03199892 0,03929049 ! leukocyte chemotaxis GO:0030595 32 32 0,000 0,03199892 0,03927727 GO:0060326|cell chemotaxis, ! negative regulation of leukocyte activation GO:0002695 35 32 0,000 0,03199892 0,03926406 ! hormone biosynthetic process GO:0042446 32 32 0,000 0,03199892 0,03925086 ! microtubule organizing center part GO:0044450 46 32 0,000 0,03199892 0,03923767 ! platelet alpha granule lumen GO:0031093 35 33 0,000 0,03298308 0,04043087 ! DNA helicase activity GO:0003678 55 33 0,000 0,03298308 0,04041729 ! neural tube development GO:0021915 37 33 0,000 0,03298308 0,04040372 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 33 0,000 0,03298308 0,04039016 ! pigment biosynthetic process GO:0046148 35 33 0,000 0,03298308 0,0403766 ! regulation of cellular ketone metabolic process GO:0010565 46 33 0,000 0,03298308 0,04036306 ! negative regulation of DNA binding GO:0043392 39 33 0,000 0,03298308 0,04034952 ! NAD or NADH binding GO:0051287 36 33 0,000 0,03298308 0,040336 ! nucleotide catabolic process GO:0009166 35 33 0,000 0,03298308 0,04032248 ! B cell differentiation GO:0030183 37 33 0,000 0,03298308 0,04030897 ! regulation of Wnt receptor signaling pathway GO:0030111 36 33 0,000 0,03298308 0,04029547 ! aerobic respiration GO:0009060 35 33 0,000 0,03298308 0,04028198 ! embryonic organ development GO:0048568 41 33 0,000 0,03298308 0,0402685 ! placenta development GO:0001890 39 33 0,000 0,03298308 0,04025503 ! tissue remodeling GO:0048771 37 33 0,000 0,03298308 0,04024157 ! flagellum GO:0019861 34 33 0,000 0,03298308 0,04022811 ! L-amino acid transmembrane transporter activity GO:0015179 37 33 0,000 0,03298308 0,04021467 ! Rho protein signal transduction GO:0007266 35 33 0,000 0,03298308 0,04020123 ! cysteine-type endopeptidase inhibitor activity GO:0004869 35 33 0,000 0,03298308 0,0401878 ! odontogenesis GO:0042476 39 34 0,000 0,0339663 0,04137197 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,0339663 0,04135816 ! lipid homeostasis GO:0055088 37 34 0,000 0,0339663 0,04134436 ! telencephalon development GO:0021537 36 34 0,000 0,0339663 0,04133057 ! clathrin coat GO:0030118 41 34 0,000 0,0339663 0,04131679 ! cell growth GO:0016049 36 34 0,000 0,0339663 0,04130302 ! protein polymerization GO:0051258 38 34 0,000 0,0339663 0,04128925 ! condensed chromosome kinetochore GO:0000777 52 34 0,000 0,0339663 0,0412755 ! learning GO:0007612 51 34 0,000 0,0339663 0,04126175 ! keratinization GO:0031424 40 34 0,000 0,0339663 0,04124802 ! ovulation cycle process GO:0022602 35 34 0,000 0,0339663 0,04123429 ! regulation of striated muscle tissue development GO:0016202 40 34 0,000 0,0339663 0,04122057 ! regulation of protein import into nucleus GO:0042306 36 34 0,000 0,0339663 0,04120687 ! erythrocyte homeostasis GO:0034101 40 34 0,000 0,0339663 0,04119317 ! amino acid binding GO:0016597 40 34 0,000 0,0339663 0,04117948 ! regulation of protein stability GO:0031647 35 34 0,000 0,0339663 0,0411658 ! specific RNA polymerase II transcription factor activity GO:0003704 41 34 0,000 0,0339663 0,04115212 ! glycogen metabolic process GO:0005977 48 34 0,000 0,0339663 0,04113846 ! pyrimidine nucleotide metabolic process GO:0006220 41 34 0,000 0,0339663 0,04112481 ! acetylglucosaminyltransferase activity GO:0008375 40 34 0,000 0,0339663 0,04111116 ! epithelial tube morphogenesis GO:0060562 38 34 0,000 0,0339663 0,04109753 ! positive regulation of transcription factor activity GO:0051091 49 35 0,000 0,03494856 0,042272 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 53 35 0,000 0,03494856 0,04225799 ! response to estrogen stimulus GO:0043627 48 35 0,000 0,03494856 0,04224399 ! inner ear morphogenesis GO:0042472 46 35 0,000 0,03494856 0,04223 ! MHC protein complex GO:0042611 50 35 0,000 0,03494856 0,04221601 ! alcohol biosynthetic process GO:0046165 41 35 0,000 0,03494856 0,04220204 ! vesicle lumen GO:0031983 38 35 0,000 0,03494856 0,04218807 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! female gonad development GO:0008585 37 35 0,000 0,03494856 0,04217412 ! mesenchymal cell development GO:0014031 40 35 0,000 0,03494856 0,04216017 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! neutral lipid metabolic process GO:0006638 47 35 0,000 0,03494856 0,04214623 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 37 35 0,000 0,03494856 0,04213231 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 41 35 0,000 0,03494856 0,04211839 ! regulation of proteolysis GO:0030162 37 35 0,000 0,03494856 0,04210448 ! ovulation cycle GO:0042698 37 35 0,000 0,03494856 0,04209058 ! intramolecular oxidoreductase activity GO:0016860 35 35 0,000 0,03494856 0,04207669 ! positive regulation of catabolic process GO:0009896 38 35 0,000 0,03494856 0,0420628 ! collagen GO:0005581 54 35 0,000 0,03494856 0,04204893 ! glucan metabolic process GO:0044042 49 35 0,000 0,03494856 0,04203507 GO:0006073|cellular glucan metabolic process, ! regulation of muscle development GO:0048634 42 35 0,000 0,03494856 0,04202121 ! ER to Golgi vesicle-mediated transport GO:0006888 43 35 0,000 0,03494856 0,04200737 ! histone methyltransferase activity GO:0042054 40 35 0,000 0,03494856 0,04199353 ! cation:sugar symporter activity GO:0005402 37 35 0,000 0,03494856 0,0419797 GO:0005351|sugar:hydrogen symporter activity, ! carbohydrate homeostasis GO:0033500 49 35 0,000 0,03494856 0,04196588 GO:0042593|glucose homeostasis, ! cytosolic small ribosomal subunit GO:0022627 36 35 0,000 0,03494856 0,04195208 ! maintenance of protein location GO:0045185 45 35 0,000 0,03494856 0,04193828 ! polyol metabolic process GO:0019751 46 35 0,000 0,03494856 0,04192448 ! cytokinesis GO:0000910 38 35 0,000 0,03494856 0,0419107 ! O-acyltransferase activity GO:0008374 36 35 0,000 0,03494856 0,04189693 ! purinergic nucleotide receptor activity GO:0001614 40 36 0,000 0,03592988 0,0430592 GO:0016502|nucleotide receptor activity, ! mitochondrial respiratory chain complex I GO:0005747 37 36 0,000 0,03592988 0,04304506 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 42 36 0,000 0,03592988 0,04303093 ! positive regulation of neurogenesis GO:0050769 38 36 0,000 0,03592988 0,04301681 ! negative regulation of cell activation GO:0050866 40 36 0,000 0,03592988 0,04300269 ! inositol or phosphatidylinositol kinase activity GO:0004428 51 36 0,000 0,03592988 0,04298859 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 36 0,000 0,03592988 0,0429745 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 38 36 0,000 0,03592988 0,04296041 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 36 0,000 0,03592988 0,04294633 ! hormone-mediated signaling GO:0009755 41 36 0,000 0,03592988 0,04293227 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 44 36 0,000 0,03592988 0,04291821 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 42 36 0,000 0,03592988 0,04290416 ! energy coupled proton transport, down electrochemical gradient GO:0015985 37 36 0,000 0,03592988 0,04289012 GO:0015986|ATP synthesis coupled proton transport, ! female gamete generation GO:0007292 39 36 0,000 0,03592988 0,04287609 ! maintenance of location in cell GO:0051651 38 36 0,000 0,03592988 0,04286207 ! activation of adenylate cyclase activity GO:0007190 44 37 0,000 0,03691026 0,0440172 ! regulation of hormone secretion GO:0046883 43 37 0,000 0,03691026 0,04400282 ! sugar transmembrane transporter activity GO:0051119 39 37 0,000 0,03691026 0,04398844 GO:0015144|carbohydrate transmembrane transporter activity, ! regulation of Rab protein signal transduction GO:0032483 40 37 0,000 0,03691026 0,04397408 GO:0032313|regulation of Rab GTPase activity, ! regulation of action potential in neuron GO:0019228 44 37 0,000 0,03691026 0,04395972 ! glycerol ether metabolic process GO:0006662 49 37 0,000 0,03691026 0,04394537 ! endoribonuclease activity GO:0004521 48 37 0,000 0,03691026 0,04393104 ! isoprenoid metabolic process GO:0006720 41 37 0,000 0,03691026 0,04391671 ! pigmentation GO:0043473 51 37 0,000 0,03691026 0,04390239 ! regulation of neuron projection development GO:0010975 43 37 0,000 0,03691026 0,04388808 ! condensed chromosome, centromeric region GO:0000779 55 37 0,000 0,03691026 0,04387378 ! monocarboxylic acid transport GO:0015718 43 37 0,000 0,03691026 0,04385949 ! sensory perception of taste GO:0050909 37 37 0,000 0,03691026 0,0438452 ! cell junction organization GO:0034330 44 37 0,000 0,03691026 0,04383093 ! skeletal muscle fiber development GO:0048741 41 37 0,000 0,03691026 0,04381667 ! development of primary female sexual characteristics GO:0046545 40 37 0,000 0,03691026 0,04380241 GO:0046660|female sex differentiation, ! NADH dehydrogenase (ubiquinone) activity GO:0008137 38 37 0,000 0,03691026 0,04378817 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! ion transmembrane transport GO:0034220 38 37 0,000 0,03691026 0,04377393 ! regulation of lymphocyte mediated immunity GO:0002706 43 37 0,000 0,03691026 0,04375971 ! coated pit GO:0005905 44 37 0,000 0,03691026 0,04374549 ! positive regulation of adenylate cyclase activity GO:0045762 45 38 0,000 0,03788969 0,04489171 ! negative regulation of binding GO:0051100 44 38 0,000 0,03788969 0,04487714 ! organic ether metabolic process GO:0018904 50 38 0,000 0,03788969 0,04486257 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 43 38 0,000 0,03788969 0,04484802 ! regulation of lymphocyte differentiation GO:0045619 51 38 0,000 0,03788969 0,04483347 ! carbon-carbon lyase activity GO:0016830 41 38 0,000 0,03788969 0,04481893 ! hydro-lyase activity GO:0016836 44 38 0,000 0,03788969 0,0448044 ! synapse organization GO:0050808 43 38 0,000 0,03788969 0,04478989 ! viral infectious cycle GO:0019058 40 38 0,000 0,03788969 0,04477538 ! phosphoinositide biosynthetic process GO:0046489 41 38 0,000 0,03788969 0,04476088 ! negative regulation of protein complex disassembly GO:0043242 42 38 0,000 0,03788969 0,04474639 ! organic anion transport GO:0015711 42 38 0,000 0,03788969 0,04473191 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 52 38 0,000 0,03788969 0,04471743 ! monosaccharide binding GO:0048029 41 38 0,000 0,03788969 0,04470297 ! muscle fiber development GO:0048747 42 38 0,000 0,03788969 0,04468852 ! development of primary male sexual characteristics GO:0046546 46 38 0,000 0,03788969 0,04467407 ! phagocytosis GO:0006909 44 38 0,000 0,03788969 0,04465964 ! general RNA polymerase II transcription factor activity GO:0016251 43 38 0,000 0,03788969 0,04464522 ! DNA-directed RNA polymerase activity GO:0003899 49 38 0,000 0,03788969 0,0446308 GO:0034062|RNA polymerase activity, ! extrinsic to plasma membrane GO:0019897 43 38 0,000 0,03788969 0,04461639 ! cytosolic large ribosomal subunit GO:0022625 43 38 0,000 0,03788969 0,044602 ! Rab GTPase activator activity GO:0005097 41 38 0,000 0,03788969 0,04458761 ! cellular response to insulin stimulus GO:0032869 47 38 0,000 0,03788969 0,04457323 ! monocarboxylic acid binding GO:0033293 44 39 0,000 0,03886818 0,04570958 ! induction of apoptosis by extracellular signals GO:0008624 44 39 0,000 0,03886818 0,04569485 ! heterocycle biosynthetic process GO:0018130 51 39 0,000 0,03886818 0,04568012 ! positive regulation of DNA binding GO:0043388 53 39 0,000 0,03886818 0,04566541 ! T cell differentiation GO:0030217 64 39 0,000 0,03886818 0,04565071 ! DNA-dependent ATPase activity GO:0008094 63 39 0,000 0,03886818 0,04563602 ! cell fate specification GO:0001708 55 39 0,000 0,03886818 0,04562133 ! positive regulation of cyclase activity GO:0031281 46 39 0,000 0,03886818 0,04560666 ! regulation of adaptive immune response GO:0002819 44 39 0,000 0,03886818 0,045592 ! receptor-mediated endocytosis GO:0006898 44 39 0,000 0,03886818 0,04557734 ! regulation of metal ion transport GO:0010959 45 39 0,000 0,03886818 0,0455627 ! energy reserve metabolic process GO:0006112 53 39 0,000 0,03886818 0,04554806 ! amine receptor activity GO:0008227 48 39 0,000 0,03886818 0,04553343 ! cytoskeleton-dependent intracellular transport GO:0030705 42 39 0,000 0,03886818 0,04551881 ! embryonic skeletal system morphogenesis GO:0048704 46 39 0,000 0,03886818 0,04550421 ! neuropeptide receptor activity GO:0008188 41 39 0,000 0,03886818 0,04548961 ! double-strand break repair GO:0006302 70 39 0,000 0,03886818 0,04547502 ! pigment metabolic process GO:0042440 43 39 0,000 0,03886818 0,04546044 ! damaged DNA binding GO:0003684 51 40 0,000 0,03984572 0,04658884 ! regulation of intracellular protein transport GO:0033157 43 40 0,000 0,03984572 0,04657392 ! peroxisomal membrane GO:0005778 44 40 0,000 0,03984572 0,046559 GO:0031903|microbody membrane, ! actin filament binding GO:0051015 41 40 0,000 0,03984572 0,04654409 ! ribonucleoside metabolic process GO:0009119 47 40 0,000 0,03984572 0,04652919 ! biopolymer methylation GO:0043414 45 40 0,000 0,03984572 0,0465143 ! neuron migration GO:0001764 43 40 0,000 0,03984572 0,04649942 ! regulation of protein secretion GO:0050708 45 40 0,000 0,03984572 0,04648455 ! oxidoreduction coenzyme metabolic process GO:0006733 45 40 0,000 0,03984572 0,04646969 ! dorsal/ventral pattern formation GO:0009953 42 40 0,000 0,03984572 0,04645484 ! regulation of actin filament polymerization GO:0030833 53 40 0,000 0,03984572 0,04644 ! positive regulation of defense response GO:0031349 41 40 0,000 0,03984572 0,04642516 ! mammary gland development GO:0030879 47 40 0,000 0,03984572 0,04641034 ! neuropeptide binding GO:0042923 42 40 0,000 0,03984572 0,04639553 ! regulation of tube size GO:0035150 44 40 0,000 0,03984572 0,04638072 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 42 40 0,000 0,03984572 0,04636593 ! positive regulation of gene-specific transcription GO:0043193 46 40 0,000 0,03984572 0,04635114 ! regulation of leukocyte mediated immunity GO:0002703 46 40 0,000 0,03984572 0,04633637 ! inorganic anion transmembrane transporter activity GO:0015103 43 40 0,000 0,03984572 0,0463216 ! chromatin remodeling GO:0006338 44 40 0,000 0,03984572 0,04630685 ! solute:hydrogen symporter activity GO:0015295 44 40 0,000 0,03984572 0,0462921 ! protein amino acid N-linked glycosylation GO:0006487 46 41 0,000 0,04082232 0,0474116 ! Notch signaling pathway GO:0007219 46 41 0,000 0,04082232 0,04739651 ! keratin filament GO:0045095 44 41 0,000 0,04082232 0,04738143 ! peptide metabolic process GO:0006518 42 41 0,000 0,04082232 0,04736636 ! polysaccharide biosynthetic process GO:0000271 42 41 0,000 0,04082232 0,0473513 ! late endosome membrane GO:0031902 45 41 0,000 0,04082232 0,04733625 ! icosanoid metabolic process GO:0006690 51 41 0,000 0,04082232 0,04732121 ! positive regulation of lyase activity GO:0051349 48 41 0,000 0,04082232 0,04730617 ! integral to endoplasmic reticulum membrane GO:0030176 43 41 0,000 0,04082232 0,04729115 ! glycolysis GO:0006096 43 41 0,000 0,04082232 0,04727614 ! branching morphogenesis of a tube GO:0048754 54 41 0,000 0,04082232 0,04726113 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 51 41 0,000 0,04082232 0,04724614 ! proton-transporting two-sector ATPase complex GO:0016469 42 41 0,000 0,04082232 0,04723116 ! response to reactive oxygen species GO:0000302 49 42 0,000 0,04179798 0,04834466 ! cellular amide metabolic process GO:0043603 56 42 0,000 0,04179798 0,04832933 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 43 42 0,000 0,04179798 0,04831402 ! ER-Golgi intermediate compartment GO:0005793 52 42 0,000 0,04179798 0,04829872 ! regulation of multicellular organism growth GO:0040014 46 42 0,000 0,04179798 0,04828342 ! integral to Golgi membrane GO:0030173 55 42 0,000 0,04179798 0,04826814 ! developmental growth GO:0048589 45 42 0,000 0,04179798 0,04825286 ! structural constituent of muscle GO:0008307 46 42 0,000 0,04179798 0,0482376 ! mitochondrial transport GO:0006839 45 42 0,000 0,04179798 0,04822234 ! protein methyltransferase activity GO:0008276 49 42 0,000 0,04179798 0,0482071 ! metal cluster binding GO:0051540 47 42 0,000 0,04179798 0,04819186 GO:0051536|iron-sulfur cluster binding, ! feeding behavior GO:0007631 48 42 0,000 0,04179798 0,04817663 ! ribonucleoprotein complex assembly GO:0022618 47 42 0,000 0,04179798 0,04816142 ! RNA catabolic process GO:0006401 49 43 0,000 0,04277271 0,04926897 ! ear morphogenesis GO:0042471 56 43 0,000 0,04277271 0,04925342 ! cellular amino acid biosynthetic process GO:0008652 49 43 0,000 0,04277271 0,04923788 ! regulation of epithelial cell proliferation GO:0050678 50 43 0,000 0,04277271 0,04922234 ! cell recognition GO:0008037 51 43 0,000 0,04277271 0,04920682 ! positive regulation of cytokine production GO:0001819 46 43 0,000 0,04277271 0,04919131 ! epithelial cell differentiation GO:0030855 56 43 0,000 0,04277271 0,0491758 ! gliogenesis GO:0042063 46 43 0,000 0,04277271 0,04916031 ! endosome transport GO:0016197 48 43 0,000 0,04277271 0,04914483 ! striated muscle contraction GO:0006941 45 43 0,000 0,04277271 0,04912935 ! positive regulation of cytokine biosynthetic process GO:0042108 48 43 0,000 0,04277271 0,04911389 ! antioxidant activity GO:0016209 53 43 0,000 0,04277271 0,04909844 ! sulfur compound biosynthetic process GO:0044272 47 43 0,000 0,04277271 0,04908299 ! vascular process in circulatory system GO:0003018 48 43 0,000 0,04277271 0,04906756 ! histone modification GO:0016570 45 43 0,000 0,04277271 0,04905213 ! cellular amino acid derivative biosynthetic process GO:0042398 55 43 0,000 0,04277271 0,04903672 ! regulation of nucleocytoplasmic transport GO:0046822 46 44 0,000 0,04374649 0,05013735 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 50 44 0,000 0,04374649 0,0501216 ! negative regulation of cell migration GO:0030336 53 44 0,000 0,04374649 0,05010587 ! ATP synthesis coupled electron transport GO:0042773 45 44 0,000 0,04374649 0,05009014 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! nucleoside monophosphate biosynthetic process GO:0009124 50 44 0,000 0,04374649 0,05007442 ! chemokine activity GO:0008009 48 44 0,000 0,04374649 0,05005872 ! ruffle GO:0001726 50 44 0,000 0,04374649 0,05004302 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 51 44 0,000 0,04374649 0,05002733 ! regulation of neuron apoptosis GO:0043523 58 44 0,000 0,04374649 0,05001165 ! cartilage development GO:0051216 48 44 0,000 0,04374649 0,04999598 ! membrane fusion GO:0006944 52 44 0,000 0,04374649 0,04998033 ! channel regulator activity GO:0016247 54 44 0,000 0,04374649 0,04996468 ! excretion GO:0007588 53 44 0,000 0,04374649 0,04994904 ! male sex differentiation GO:0046661 52 44 0,000 0,04374649 0,04993341 ! protein phosphatase regulator activity GO:0019888 50 44 0,000 0,04374649 0,04991779 ! RNA elongation from RNA polymerase II promoter GO:0006368 49 44 0,000 0,04374649 0,04990218 ! amino acid activation GO:0043038 45 44 0,000 0,04374649 0,04988658 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! microbody part GO:0044438 48 44 0,000 0,04374649 0,04987099 GO:0044439|peroxisomal part, ! positive regulation of binding GO:0051099 59 45 0,000 0,04471933 0,05096411 ! solute:sodium symporter activity GO:0015370 51 45 0,000 0,04471933 0,05094819 ! transferase activity, transferring pentosyl groups GO:0016763 50 45 0,000 0,04471933 0,05093229 ! organellar ribosome GO:0000313 46 45 0,000 0,04471933 0,05091639 GO:0005761|mitochondrial ribosome, ! platelet alpha granule GO:0031091 49 45 0,000 0,04471933 0,0509005 ! single-stranded DNA binding GO:0003697 48 45 0,000 0,04471933 0,05088463 ! intrinsic to Golgi membrane GO:0031228 60 45 0,000 0,04471933 0,05086876 ! transport vesicle GO:0030133 53 45 0,000 0,04471933 0,0508529 ! regulation of endocytosis GO:0030100 52 45 0,000 0,04471933 0,05083706 ! ligase activity, forming carbon-oxygen bonds GO:0016875 47 45 0,000 0,04471933 0,05082122 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! regulation of protein complex disassembly GO:0043244 49 45 0,000 0,04471933 0,05080539 ! unsaturated fatty acid metabolic process GO:0033559 55 45 0,000 0,04471933 0,05078958 ! regulation of T cell proliferation GO:0042129 53 45 0,000 0,04471933 0,05077377 ! regulation of myeloid leukocyte differentiation GO:0002761 54 45 0,000 0,04471933 0,05075797 ! DNA-dependent DNA replication GO:0006261 66 45 0,000 0,04471933 0,05074218 ! coated vesicle membrane GO:0030662 52 45 0,000 0,04471933 0,0507264 ! covalent chromatin modification GO:0016569 47 45 0,000 0,04471933 0,05071064 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 51 45 0,000 0,04471933 0,05069488 ! synaptosome GO:0019717 50 45 0,000 0,04471933 0,05067913 ! chemokine receptor binding GO:0042379 50 45 0,000 0,04471933 0,05066339 ! regulation of action potential GO:0001508 56 46 0,000 0,04569124 0,05174841 ! immunoglobulin mediated immune response GO:0016064 51 46 0,000 0,04569124 0,05173235 ! phosphatase regulator activity GO:0019208 53 46 0,000 0,04569124 0,0517163 ! regulation of inflammatory response GO:0050727 49 46 0,000 0,04569124 0,05170026 ! eye morphogenesis GO:0048592 57 46 0,000 0,04569124 0,05168423 ! regulation of JNK cascade GO:0046328 53 46 0,000 0,04569124 0,0516682 ! methylation GO:0032259 51 46 0,000 0,04569124 0,05165219 ! positive regulation of protein transport GO:0051222 50 46 0,000 0,04569124 0,05163619 ! regulation of ion transport GO:0043269 54 46 0,000 0,04569124 0,0516202 ! leukocyte migration GO:0050900 49 46 0,000 0,04569124 0,05160422 ! sulfotransferase activity GO:0008146 54 46 0,000 0,04569124 0,05158825 ! JNK cascade GO:0007254 48 46 0,000 0,04569124 0,05157229 ! SH3/SH2 adaptor activity GO:0005070 52 46 0,000 0,04569124 0,05155633 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 54 47 0,000 0,0466622 0,05263566 ! auxiliary transport protein activity GO:0015457 58 47 0,000 0,0466622 0,05261939 ! regulation of actin polymerization or depolymerization GO:0008064 60 47 0,000 0,0466622 0,05260313 ! microtubule binding GO:0008017 61 47 0,000 0,0466622 0,05258688 ! morphogenesis of a branching structure GO:0001763 70 47 0,000 0,0466622 0,05257064 ! carbon-oxygen lyase activity GO:0016835 53 47 0,000 0,0466622 0,05255441 ! regulation of protein polymerization GO:0032271 60 47 0,000 0,0466622 0,05253818 ! viral reproductive process GO:0022415 53 47 0,000 0,0466622 0,05252197 ! RNA elongation GO:0006354 52 47 0,000 0,0466622 0,05250577 ! negative regulation of immune system process GO:0002683 58 47 0,000 0,0466622 0,05248958 ! mRNA binding GO:0003729 65 47 0,000 0,0466622 0,0524734 ! axon GO:0030424 53 48 0,000 0,04763224 0,05354773 ! protein amino acid lipidation GO:0006497 53 48 0,000 0,04763224 0,05353124 ! stress-activated protein kinase signaling pathway GO:0031098 50 48 0,000 0,04763224 0,05351475 ! proteasome complex GO:0000502 50 48 0,000 0,04763224 0,05349828 ! glutamine family amino acid metabolic process GO:0009064 62 48 0,000 0,04763224 0,05348181 ! protein homooligomerization GO:0051260 63 48 0,000 0,04763224 0,05346535 ! regulation of cell projection organization GO:0031344 54 48 0,000 0,04763224 0,05344891 ! kinetochore GO:0000776 69 48 0,000 0,04763224 0,05343247 ! detection of stimulus involved in sensory perception GO:0050906 53 48 0,000 0,04763224 0,05341605 ! growth factor receptor binding GO:0070851 58 48 0,000 0,04763224 0,05339963 ! N-methyltransferase activity GO:0008170 53 48 0,000 0,04763224 0,05338323 ! inner ear development GO:0048839 60 48 0,000 0,04763224 0,05336683 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 57 48 0,000 0,04763224 0,05335044 ! amino acid transmembrane transporter activity GO:0015171 53 48 0,000 0,04763224 0,05333407 ! chromatin remodeling complex GO:0016585 54 48 0,000 0,04763224 0,0533177 ! B cell mediated immunity GO:0019724 53 48 0,000 0,04763224 0,05330135 ! steroid hormone receptor activity GO:0003707 61 48 0,000 0,04763224 0,053285 ! regulation of cell shape GO:0008360 55 48 0,000 0,04763224 0,05326867 ! establishment of organelle localization GO:0051656 58 48 0,000 0,04763224 0,05325234 ! cell cortex part GO:0044448 54 48 0,000 0,04763224 0,05323603 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 52 49 0,000 0,04860133 0,0543025 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 54 49 0,000 0,04860133 0,05428587 ! Golgi-associated vesicle GO:0005798 59 49 0,000 0,04860133 0,05426926 ! lipid modification GO:0030258 55 49 0,000 0,04860133 0,05425265 ! synaptic vesicle GO:0008021 56 49 0,000 0,04860133 0,05423606 ! regulation of gene expression, epigenetic GO:0040029 64 49 0,000 0,04860133 0,05421947 ! pyridoxal phosphate binding GO:0030170 63 49 0,000 0,04860133 0,05420289 GO:0070279|vitamin B6 binding, ! exonuclease activity GO:0004527 79 49 0,000 0,04860133 0,05418633 ! maintenance of location GO:0051235 62 49 0,000 0,04860133 0,05416977 ! negative regulation of cell motion GO:0051271 60 49 0,000 0,04860133 0,05415323 ! regulation of actin filament length GO:0030832 62 49 0,000 0,04860133 0,05413669 ! regulation of muscle contraction GO:0006937 57 49 0,000 0,04860133 0,05412017 ! negative regulation of cytoskeleton organization GO:0051494 73 49 0,000 0,04860133 0,05410365 ! nucleotide-excision repair GO:0006289 53 49 0,000 0,04860133 0,05408715 ! respiratory electron transport chain GO:0022904 51 50 0,000 0,0495695 0,05514777 ! cytokine-mediated signaling pathway GO:0019221 56 50 0,000 0,0495695 0,05513095 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,0495695 0,05511415 ! embryonic skeletal system development GO:0048706 59 50 0,000 0,0495695 0,05509736 ! glucose catabolic process GO:0006007 54 50 0,000 0,0495695 0,05508057 ! aging GO:0007568 92 50 0,000 0,0495695 0,0550638 ! generation of a signal involved in cell-cell signaling GO:0003001 59 50 0,000 0,0495695 0,05504704 ! heart morphogenesis GO:0003007 57 50 0,000 0,0495695 0,05503029 ! integrin binding GO:0005178 56 50 0,000 0,0495695 0,05501355 ! detection of abiotic stimulus GO:0009582 56 50 0,000 0,0495695 0,05499681 ! regulation of angiogenesis GO:0045765 56 51 0,000 0,05053673 0,0560529 ! positive regulation of cell migration GO:0030335 63 51 0,000 0,05053673 0,05603586 ! regulation of ossification GO:0030278 59 51 0,000 0,05053673 0,05601883 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 60 51 0,000 0,05053673 0,05600182 ! cellular polysaccharide metabolic process GO:0044264 65 51 0,000 0,05053673 0,05598481 ! endocrine system development GO:0035270 55 51 0,000 0,05053673 0,05596781 ! germ cell development GO:0007281 56 51 0,000 0,05053673 0,05595083 ! transferase activity, transferring sulfur-containing groups GO:0016782 60 52 0,000 0,05150302 0,05700335 ! regulation of cellular component size GO:0032535 66 52 0,000 0,05150302 0,05698606 ! carbohydrate transport GO:0008643 57 52 0,000 0,05150302 0,05696878 ! ubiquitin thiolesterase activity GO:0004221 64 52 0,000 0,05150302 0,05695151 ! nucleoside monophosphate metabolic process GO:0009123 58 52 0,000 0,05150302 0,05693425 ! cell maturation GO:0048469 68 52 0,000 0,05150302 0,056917 ! regulation of intracellular transport GO:0032386 57 52 0,000 0,05150302 0,05689977 ! vesicle organization GO:0016050 59 52 0,000 0,05150302 0,05688254 ! kidney development GO:0001822 55 52 0,000 0,05150302 0,05686532 ! cell redox homeostasis GO:0045454 57 52 0,000 0,05150302 0,05684812 ! lipoprotein biosynthetic process GO:0042158 57 52 0,000 0,05150302 0,05683092 ! lipid transporter activity GO:0005319 58 52 0,000 0,05150302 0,05681374 ! cytokine receptor activity GO:0004896 54 52 0,000 0,05150302 0,05679656 ! antiporter activity GO:0015297 53 52 0,000 0,05150302 0,0567794 ! embryonic limb morphogenesis GO:0030326 62 53 0,000 0,05246839 0,05782619 GO:0035113|embryonic appendage morphogenesis, ! glycosaminoglycan metabolic process GO:0030203 60 53 0,000 0,05246839 0,05780872 ! N-acetyltransferase activity GO:0008080 59 53 0,000 0,05246839 0,05779127 ! basement membrane GO:0005604 55 53 0,000 0,05246839 0,05777383 ! water-soluble vitamin metabolic process GO:0006767 59 53 0,000 0,05246839 0,05775639 ! negative regulation of response to stimulus GO:0048585 68 53 0,000 0,05246839 0,05773897 ! viral reproduction GO:0016032 59 53 0,000 0,05246839 0,05772156 ! chloride transport GO:0006821 60 53 0,000 0,05246839 0,05770416 ! oxygen and reactive oxygen species metabolic process GO:0006800 58 53 0,000 0,05246839 0,05768676 ! regulation of DNA replication GO:0006275 75 53 0,000 0,05246839 0,05766938 ! heterocycle catabolic process GO:0046700 56 53 0,000 0,05246839 0,05765201 ! integrin-mediated signaling pathway GO:0007229 59 53 0,000 0,05246839 0,05763465 ! single fertilization GO:0007338 58 53 0,000 0,05246839 0,0576173 ! activation of phospholipase C activity GO:0007202 61 54 0,000 0,05343282 0,05865872 GO:0010863|positive regulation of phospholipase C activity, ! double-stranded DNA binding GO:0003690 63 54 0,000 0,05343282 0,05864108 ! mitochondrial respiratory chain GO:0005746 55 54 0,000 0,05343282 0,05862344 ! nucleoside metabolic process GO:0009116 62 54 0,000 0,05343282 0,05860582 ! coated membrane GO:0048475 65 54 0,000 0,05343282 0,0585882 GO:0030117|membrane coat, ! nucleosome GO:0000786 59 54 0,000 0,05343282 0,0585706 ! regulation of protein complex assembly GO:0043254 67 54 0,000 0,05343282 0,058553 ! cellular defense response GO:0006968 61 54 0,000 0,05343282 0,05853542 ! gastrulation GO:0007369 62 54 0,000 0,05343282 0,05851785 ! dendrite GO:0030425 60 55 0,000 0,05439633 0,05955516 ! positive regulation of phospholipase activity GO:0010518 62 55 0,000 0,05439633 0,0595373 ! respiratory chain GO:0070469 57 55 0,000 0,05439633 0,05951944 ! coenzyme biosynthetic process GO:0009108 68 55 0,000 0,05439633 0,05950159 ! extracellular matrix organization GO:0030198 77 55 0,000 0,05439633 0,05948375 ! positive regulation of cell motion GO:0051272 69 55 0,000 0,05439633 0,05946593 ! protein amino acid autophosphorylation GO:0046777 61 55 0,000 0,05439633 0,05944811 ! translation initiation factor activity GO:0003743 66 55 0,000 0,05439633 0,05943031 ! regulation of bone remodeling GO:0046850 64 56 0,000 0,0553589 0,06046386 ! heat shock protein binding GO:0031072 62 56 0,000 0,0553589 0,06044576 ! late endosome GO:0005770 60 56 0,000 0,0553589 0,06042767 ! regulation of phospholipase activity GO:0010517 63 56 0,000 0,0553589 0,0604096 ! sphingolipid metabolic process GO:0006665 60 56 0,000 0,0553589 0,06039153 ! intrinsic to endoplasmic reticulum membrane GO:0031227 61 56 0,000 0,0553589 0,06037348 ! ribonuclease activity GO:0004540 67 56 0,000 0,0553589 0,06035543 ! positive regulation of T cell activation GO:0050870 74 56 0,000 0,0553589 0,0603374 ! mesoderm development GO:0007498 67 56 0,000 0,0553589 0,06031938 ! antigen processing and presentation GO:0019882 73 56 0,000 0,0553589 0,06030137 ! proton transport GO:0015992 59 56 0,000 0,0553589 0,06028337 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 57 0,000 0,05632055 0,06131226 ! chromosome segregation GO:0007059 92 57 0,000 0,05632055 0,06129396 ! glycerophospholipid biosynthetic process GO:0046474 71 57 0,000 0,05632055 0,06127568 ! diacylglycerol binding GO:0019992 65 57 0,000 0,05632055 0,06125742 ! B cell activation GO:0042113 63 57 0,000 0,05632055 0,06123916 ! small ribosomal subunit GO:0015935 58 57 0,000 0,05632055 0,06122091 ! detection of external stimulus GO:0009581 64 57 0,000 0,05632055 0,06120267 ! occluding junction GO:0070160 75 58 0,000 0,05728127 0,06222813 GO:0005923|tight junction, ! hydrogen transport GO:0006818 61 58 0,000 0,05728127 0,06220961 ! receptor signaling protein serine/threonine kinase activity GO:0004702 64 58 0,000 0,05728127 0,06219109 ! lymphocyte mediated immunity GO:0002449 65 58 0,000 0,05728127 0,06217259 ! response to nutrient GO:0007584 68 58 0,000 0,05728127 0,0621541 ! large ribosomal subunit GO:0015934 64 58 0,000 0,05728127 0,06213562 ! regulation of tissue remodeling GO:0034103 66 58 0,000 0,05728127 0,06211714 ! ligand-dependent nuclear receptor activity GO:0004879 72 58 0,000 0,05728127 0,06209868 ! myosin complex GO:0016459 64 58 0,000 0,05728127 0,06208024 ! regulation of gene-specific transcription GO:0032583 69 59 0,000 0,05824106 0,06310169 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 62 59 0,000 0,05824106 0,06308296 GO:0051213|dioxygenase activity, ! muscle cell differentiation GO:0042692 77 59 0,000 0,05824106 0,06306423 ! actin filament organization GO:0007015 65 59 0,000 0,05824106 0,06304552 ! regulation of heart contraction GO:0008016 71 59 0,000 0,05824106 0,06302682 ! hexose catabolic process GO:0019320 64 59 0,000 0,05824106 0,06300813 ! cellular amino acid catabolic process GO:0009063 63 59 0,000 0,05824106 0,06298945 ! response to steroid hormone stimulus GO:0048545 74 59 0,000 0,05824106 0,06297078 ! cell projection assembly GO:0030031 79 59 0,000 0,05824106 0,06295212 ! regulation of cellular response to stress GO:0080135 79 59 0,000 0,05824106 0,06293347 ! appendage morphogenesis GO:0035107 68 59 0,000 0,05824106 0,06291484 GO:0035108|limb morphogenesis, ! homeostasis of number of cells GO:0048872 67 59 0,000 0,05824106 0,06289621 ! fertilization GO:0009566 65 59 0,000 0,05824106 0,0628776 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 62 59 0,000 0,05824106 0,06285899 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 69 59 0,000 0,05824106 0,0628404 ! adult behavior GO:0030534 72 59 0,000 0,05824106 0,06282182 ! organelle localization GO:0051640 70 59 0,000 0,05824106 0,06280325 ! positive regulation of secretion GO:0051047 66 60 0,000 0,05919993 0,06381836 ! molecular adaptor activity GO:0060090 73 60 0,000 0,05919993 0,06379951 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 63 60 0,000 0,05919993 0,06378067 ! phosphoinositide metabolic process GO:0030384 68 60 0,000 0,05919993 0,06376184 ! copper ion binding GO:0005507 85 60 0,000 0,05919993 0,06374302 ! positive regulation of lipase activity GO:0060193 68 60 0,000 0,05919993 0,06372421 ! activation of immune response GO:0002253 72 60 0,000 0,05919993 0,06370541 ! cell cycle checkpoint GO:0000075 91 60 0,000 0,05919993 0,06368663 ! appendage development GO:0048736 69 60 0,000 0,05919993 0,06366785 GO:0060173|limb development, ! regulation of vesicle-mediated transport GO:0060627 69 60 0,000 0,05919993 0,06364909 ! secondary metabolic process GO:0019748 67 60 0,000 0,05919993 0,06363033 ! cellular hormone metabolic process GO:0034754 64 61 0,000 0,06015787 0,06464092 ! ear development GO:0043583 76 61 0,000 0,06015787 0,06462188 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 68 61 0,000 0,06015787 0,06460286 ! learning or memory GO:0007611 79 61 0,000 0,06015787 0,06458385 ! camera-type eye development GO:0043010 69 61 0,000 0,06015787 0,06456485 ! transcription initiation from RNA polymerase II promoter GO:0006367 69 61 0,000 0,06015787 0,06454586 ! regulation of transcription factor activity GO:0051090 80 62 0,000 0,06111489 0,0655534 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 90 62 0,000 0,06111489 0,06553413 ! lysosomal membrane GO:0005765 69 62 0,000 0,06111489 0,06551488 ! membrane lipid metabolic process GO:0006643 76 62 0,000 0,06111489 0,06549563 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 77 62 0,000 0,06111489 0,06547639 ! skeletal system morphogenesis GO:0048705 83 62 0,000 0,06111489 0,06545717 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 77 62 0,000 0,06111489 0,06543796 ! chloride channel activity GO:0005254 72 62 0,000 0,06111489 0,06541876 ! cell soma GO:0043025 68 62 0,000 0,06111489 0,06539957 ! microtubule motor activity GO:0003777 94 62 0,000 0,06111489 0,06538039 ! protein maturation by peptide bond cleavage GO:0051605 69 62 0,000 0,06111489 0,06536122 ! FAD binding GO:0050660 71 63 0,000 0,06207099 0,06636429 ! urogenital system development GO:0001655 75 63 0,000 0,06207099 0,06634485 ! regulation of synaptic transmission GO:0050804 79 63 0,000 0,06207099 0,06632541 ! aminoglycan metabolic process GO:0006022 70 63 0,000 0,06207099 0,06630599 ! cAMP-mediated signaling GO:0019933 75 63 0,000 0,06207099 0,06628658 ! amine transmembrane transporter activity GO:0005275 69 63 0,000 0,06207099 0,06626718 ! regulation of immune effector process GO:0002697 81 63 0,000 0,06207099 0,06624779 ! respiratory tube development GO:0030323 92 64 0,000 0,06302616 0,06724757 ! intracellular protein transmembrane transport GO:0065002 83 64 0,000 0,06302616 0,0672279 ! tRNA processing GO:0008033 73 64 0,000 0,06302616 0,06720825 ! negative regulation of ligase activity GO:0051352 79 64 0,000 0,06302616 0,06718861 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of myeloid cell differentiation GO:0045637 77 64 0,000 0,06302616 0,06716898 ! adaptive immune response GO:0002250 70 64 0,000 0,06302616 0,06714936 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! transition metal ion transport GO:0000041 74 64 0,000 0,06302616 0,06712976 ! neurotransmitter transport GO:0006836 72 64 0,000 0,06302616 0,06711016 ! N-acyltransferase activity GO:0016410 70 64 0,000 0,06302616 0,06709058 ! multicellular organism reproduction GO:0032504 71 65 0,000 0,06398041 0,0680865 GO:0048609|reproductive process in a multicellular organism, ! lymphocyte differentiation GO:0030098 93 65 0,000 0,06398041 0,06806665 ! regulation of cytokine biosynthetic process GO:0042035 84 65 0,000 0,06398041 0,0680468 ! activation of MAPK activity GO:0000187 74 65 0,000 0,06398041 0,06802697 ! gonad development GO:0008406 71 65 0,000 0,06398041 0,06800715 ! acetyltransferase activity GO:0016407 73 65 0,000 0,06398041 0,06798734 ! developmental maturation GO:0021700 85 66 0,000 0,06493374 0,06898028 ! myeloid cell differentiation GO:0030099 78 66 0,000 0,06493374 0,0689602 ! tubulin binding GO:0015631 92 66 0,000 0,06493374 0,06894013 ! leukocyte mediated immunity GO:0002443 73 66 0,000 0,06493374 0,06892007 ! tube morphogenesis GO:0035239 84 66 0,000 0,06493374 0,06890002 ! cysteine-type endopeptidase activity GO:0004197 73 66 0,000 0,06493374 0,06887999 ! endoplasmic reticulum lumen GO:0005788 78 67 0,000 0,06588615 0,06986996 ! glycerolipid biosynthetic process GO:0045017 81 67 0,000 0,06588615 0,06984966 ! activation of protein kinase activity GO:0032147 83 67 0,000 0,06588615 0,06982936 ! chloride ion binding GO:0031404 79 67 0,000 0,06588615 0,06980908 ! humoral immune response GO:0006959 75 67 0,000 0,06588615 0,06978881 ! amine binding GO:0043176 77 67 0,000 0,06588615 0,06976856 ! female pregnancy GO:0007565 78 67 0,000 0,06588615 0,06974831 ! extrinsic to membrane GO:0019898 75 67 0,000 0,06588615 0,06972807 ! anion channel activity GO:0005253 77 67 0,000 0,06588615 0,06970785 ! regulation of homeostatic process GO:0032844 88 67 0,000 0,06588615 0,06968764 ! regulation of adenylate cyclase activity GO:0045761 81 68 0,000 0,06683764 0,07067354 ! amine catabolic process GO:0009310 73 68 0,000 0,06683764 0,07065306 ! negative regulation of organelle organization GO:0010639 93 68 0,000 0,06683764 0,07063259 ! monosaccharide catabolic process GO:0046365 73 68 0,000 0,06683764 0,07061214 ! respiratory system development GO:0060541 96 68 0,000 0,06683764 0,07059169 ! fatty acid biosynthetic process GO:0006633 76 69 0,000 0,06778821 0,07157494 ! regulation of transmission of nerve impulse GO:0051969 87 69 0,000 0,06778821 0,07155422 ! sarcomere GO:0030017 74 69 0,000 0,06778821 0,07153353 ! exocytosis GO:0006887 76 69 0,000 0,06778821 0,07151284 ! skeletal muscle tissue development GO:0007519 75 69 0,000 0,06778821 0,07149217 GO:0060538|skeletal muscle organ development, ! nucleosome assembly GO:0006334 87 69 0,000 0,06778821 0,0714715 ! extracellular ligand-gated ion channel activity GO:0005230 82 69 0,000 0,06778821 0,07145085 ! amine biosynthetic process GO:0009309 78 70 0,000 0,06873787 0,07243089 ! thiolester hydrolase activity GO:0016790 84 70 0,000 0,06873787 0,07240998 ! early endosome GO:0005769 104 70 0,000 0,06873787 0,07238907 ! regulation of cyclase activity GO:0031279 83 70 0,000 0,06873787 0,07236818 ! regulation of lipase activity GO:0060191 78 70 0,000 0,06873787 0,0723473 ! amino acid transport GO:0006865 76 70 0,000 0,06873787 0,07232643 ! chromatin assembly GO:0031497 88 70 0,000 0,06873787 0,07230558 ! calcium channel activity GO:0005262 86 70 0,000 0,06873787 0,07228473 ! axon guidance GO:0007411 87 70 0,000 0,06873787 0,0722639 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 73 71 0,000 0,06968661 0,0732402 ! mitochondrial outer membrane GO:0005741 81 71 0,000 0,06968661 0,07321911 ! lipoprotein metabolic process GO:0042157 76 71 0,000 0,06968661 0,07319803 ! response to hypoxia GO:0001666 84 72 0,000 0,07063443 0,07417225 ! steroid biosynthetic process GO:0006694 83 72 0,000 0,07063443 0,07415091 ! regulation of MAPKKK cascade GO:0043408 82 72 0,000 0,07063443 0,07412958 ! regulation of lyase activity GO:0051339 85 72 0,000 0,07063443 0,07410826 ! acute inflammatory response GO:0002526 91 72 0,000 0,07063443 0,07408695 ! apical junction complex GO:0043296 90 72 0,000 0,07063443 0,07406565 ! phospholipase activity GO:0004620 99 72 0,000 0,07063443 0,07404437 ! membrane raft GO:0045121 81 72 0,000 0,07063443 0,0740231 ! regulation of neurological system process GO:0031644 91 72 0,000 0,07063443 0,07400184 ! structural constituent of cytoskeleton GO:0005200 78 72 0,000 0,07063443 0,07398059 ! elevation of cytosolic calcium ion concentration GO:0007204 87 73 0,000 0,07158134 0,07495084 GO:0051480|cytosolic calcium ion homeostasis, ! response to drug GO:0042493 94 73 0,000 0,07158134 0,07492933 ! regulation of cAMP biosynthetic process GO:0030817 86 73 0,000 0,07158134 0,07490784 ! digestion GO:0007586 81 73 0,000 0,07158134 0,07488636 ! cell-matrix adhesion GO:0007160 102 74 0,000 0,07252733 0,07585428 ! response to oxygen levels GO:0070482 86 74 0,000 0,07252733 0,07583253 ! potassium channel complex GO:0034705 84 74 0,000 0,07252733 0,07581081 GO:0008076|voltage-gated potassium channel complex, ! protein-DNA complex assembly GO:0065004 101 74 0,000 0,07252733 0,07578909 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 85 74 0,000 0,07252733 0,07576739 ! one-carbon metabolic process GO:0006730 84 74 0,000 0,07252733 0,07574569 ! blood coagulation GO:0007596 90 74 0,000 0,07252733 0,07572402 GO:0050817|coagulation, ! reproductive structure development GO:0048608 89 74 0,000 0,07252733 0,07570235 ! apicolateral plasma membrane GO:0016327 92 74 0,000 0,07252733 0,0756807 ! phosphoinositide-mediated signaling GO:0048015 92 74 0,000 0,07252733 0,07565905 ! cellular lipid catabolic process GO:0044242 99 74 0,000 0,07252733 0,07563742 ! ubiquitin ligase complex GO:0000151 91 74 0,000 0,07252733 0,07561581 ! cell projection part GO:0044463 80 74 0,000 0,07252733 0,0755942 ! meiosis GO:0007126 108 75 0,000 0,07347241 0,07655737 GO:0051327|M phase of meiotic cell cycle, ! regulation of DNA binding GO:0051101 94 75 0,000 0,07347241 0,07653551 ! carboxylic acid transmembrane transporter activity GO:0046943 85 75 0,000 0,07347241 0,07651366 ! regulation of cAMP metabolic process GO:0030814 88 75 0,000 0,07347241 0,07649183 ! regulation of blood pressure GO:0008217 82 75 0,000 0,07347241 0,07647 ! transcription initiation GO:0006352 84 75 0,000 0,07347241 0,07644819 ! Ras GTPase activator activity GO:0005099 83 75 0,000 0,07347241 0,07642639 ! neuropeptide signaling pathway GO:0007218 85 76 0,000 0,07441658 0,07738646 ! defense response to bacterium GO:0042742 81 76 0,000 0,07441658 0,0773644 ! regulation of lipid metabolic process GO:0019216 98 76 0,000 0,07441658 0,07734236 ! meiotic cell cycle GO:0051321 109 76 0,000 0,07441658 0,07732033 ! regulation of neuron differentiation GO:0045664 96 76 0,000 0,07441658 0,07729832 ! protein-DNA complex GO:0032993 93 76 0,000 0,07441658 0,07727631 ! organic acid transmembrane transporter activity GO:0005342 86 76 0,000 0,07441658 0,07725432 ! development of primary sexual characteristics GO:0045137 86 76 0,000 0,07441658 0,07723235 ! cytosolic ribosome GO:0022626 82 76 0,000 0,07441658 0,07721038 ! serine-type endopeptidase inhibitor activity GO:0004867 93 76 0,000 0,07441658 0,07718843 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 84 77 0,000 0,07535984 0,0781446 ! nucleosome organization GO:0034728 96 77 0,000 0,07535984 0,07812239 ! alcohol catabolic process GO:0046164 84 77 0,000 0,07535984 0,0781002 ! vacuolar membrane GO:0005774 86 77 0,000 0,07535984 0,07807802 ! G-protein-coupled receptor binding GO:0001664 87 77 0,000 0,07535984 0,07805585 ! myofibril GO:0030016 82 77 0,000 0,07535984 0,07803369 ! protein oligomerization GO:0051259 93 77 0,000 0,07535984 0,07801155 ! phosphoric diester hydrolase activity GO:0008081 99 78 0,000 0,07630219 0,07896465 ! endonuclease activity GO:0004519 111 78 0,000 0,07630219 0,07894225 ! cofactor biosynthetic process GO:0051188 93 78 0,000 0,07630219 0,07891987 ! inorganic anion transport GO:0015698 87 78 0,000 0,07630219 0,0788975 ! regulation of protein transport GO:0051223 85 78 0,000 0,07630219 0,07887514 ! regulation of nucleotide biosynthetic process GO:0030808 91 78 0,000 0,07630219 0,0788528 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! transmembrane receptor protein kinase activity GO:0019199 95 78 0,000 0,07630219 0,07883047 ! carboxylesterase activity GO:0004091 93 78 0,000 0,07630219 0,07880815 ! protein ubiquitination GO:0016567 95 78 0,000 0,07630219 0,07878584 ! extracellular matrix structural constituent GO:0005201 96 78 0,000 0,07630219 0,07876355 ! contractile fiber part GO:0044449 83 78 0,000 0,07630219 0,07874127 ! positive regulation of MAP kinase activity GO:0043406 89 79 0,000 0,07724362 0,07969025 ! vitamin metabolic process GO:0006766 86 79 0,000 0,07724362 0,07966772 ! T cell activation GO:0042110 120 79 0,000 0,07724362 0,07964521 ! cellular response to hormone stimulus GO:0032870 94 79 0,000 0,07724362 0,0796227 ! phosphoinositide binding GO:0035091 99 79 0,000 0,07724362 0,07960021 ! eye development GO:0001654 93 80 0,000 0,07818415 0,08054668 ! ATP biosynthetic process GO:0006754 89 80 0,000 0,07818415 0,08052394 ! rhythmic process GO:0048511 90 80 0,000 0,07818415 0,08050121 ! SH3 domain binding GO:0017124 95 80 0,000 0,07818415 0,08047849 ! hemostasis GO:0007599 96 80 0,000 0,07818415 0,08045579 ! chromosome, centromeric region GO:0000775 119 80 0,000 0,07818415 0,0804331 ! regulation of cyclic nucleotide metabolic process GO:0030799 93 80 0,000 0,07818415 0,08041043 ! cell-substrate adhesion GO:0031589 109 80 0,000 0,07818415 0,08038776 ! rRNA processing GO:0006364 84 80 0,000 0,07818415 0,08036511 ! cholesterol metabolic process GO:0008203 91 81 0,000 0,07912377 0,08130803 ! vacuolar part GO:0044437 91 81 0,000 0,07912377 0,08128513 ! ossification GO:0001503 111 82 0,000 0,08006248 0,08222633 ! biogenic amine metabolic process GO:0006576 99 82 0,000 0,08006248 0,08220319 ! forebrain development GO:0030900 93 82 0,000 0,08006248 0,08218006 ! external side of plasma membrane GO:0009897 105 82 0,000 0,08006248 0,08215694 ! heparin binding GO:0008201 108 82 0,000 0,08006248 0,08213384 ! microtubule-based movement GO:0007018 119 83 0,000 0,08100029 0,08307255 ! nuclear speck GO:0016607 99 83 0,000 0,08100029 0,0830492 ! rRNA metabolic process GO:0016072 88 83 0,000 0,08100029 0,08302586 ! ATP-dependent helicase activity GO:0008026 107 83 0,000 0,08100029 0,08300254 GO:0070035|purine NTP-dependent helicase activity, ! regulation of T cell activation GO:0050863 104 83 0,000 0,08100029 0,08297923 ! regulation of establishment of protein localization GO:0070201 90 83 0,000 0,08100029 0,08295594 ! oxidative phosphorylation GO:0006119 85 83 0,000 0,08100029 0,08293265 ! contractile fiber GO:0043292 88 83 0,000 0,08100029 0,08290938 ! bone development GO:0060348 112 83 0,000 0,08100029 0,08288613 ! regulation of nucleotide metabolic process GO:0006140 96 83 0,000 0,08100029 0,08286288 ! regulation of membrane potential GO:0042391 98 83 0,000 0,08100029 0,08283965 ! cilium GO:0005929 88 83 0,000 0,08100029 0,08281644 ! regulation of DNA metabolic process GO:0051052 139 84 0,000 0,08193719 0,08375087 ! regulation of defense response GO:0031347 98 84 0,000 0,08193719 0,08372741 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 94 84 0,000 0,08193719 0,08370396 ! nitrogen compound catabolic process GO:0044270 91 84 0,000 0,08193719 0,08368053 ! DNA recombination GO:0006310 147 84 0,000 0,08193719 0,08365711 ! phospholipid biosynthetic process GO:0008654 101 85 0,000 0,08287318 0,08458908 ! protein modification by small protein conjugation GO:0032446 103 85 0,000 0,08287318 0,08456542 ! monooxygenase activity GO:0004497 92 85 0,000 0,08287318 0,08454177 ! hydrogen ion transmembrane transporter activity GO:0015078 88 85 0,000 0,08287318 0,08451813 ! protein binding, bridging GO:0030674 104 85 0,000 0,08287318 0,08449451 ! negative regulation of transport GO:0051051 98 86 0,000 0,08380827 0,08542402 ! clathrin-coated vesicle GO:0030136 100 86 0,000 0,08380827 0,08540016 ! Golgi vesicle transport GO:0048193 98 86 0,000 0,08380827 0,08537631 ! lipase activity GO:0016298 114 86 0,000 0,08380827 0,08535248 ! voltage-gated potassium channel activity GO:0005249 105 86 0,000 0,08380827 0,08532865 ! leukocyte differentiation GO:0002521 118 87 0,000 0,08474246 0,08625572 ! organelle outer membrane GO:0031968 102 88 0,000 0,08567574 0,08718134 ! carbohydrate biosynthetic process GO:0016051 95 88 0,000 0,08567574 0,08715703 ! growth factor binding GO:0019838 102 88 0,000 0,08567574 0,08713273 ! protein processing GO:0016485 100 88 0,000 0,08567574 0,08710845 ! protein tyrosine phosphatase activity GO:0004725 109 89 0,000 0,08660813 0,08803189 ! gland development GO:0048732 108 89 0,000 0,08660813 0,08800737 ! ATP metabolic process GO:0046034 100 90 0,000 0,08753961 0,08892913 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 101 90 0,000 0,08753961 0,08890437 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! peroxisome GO:0005777 100 90 0,000 0,08753961 0,08887962 GO:0042579|microbody, ! glycerophospholipid metabolic process GO:0006650 109 90 0,000 0,08753961 0,08885489 ! sterol metabolic process GO:0016125 102 90 0,000 0,08753961 0,08883018 ! negative regulation of multicellular organismal process GO:0051241 102 90 0,000 0,08753961 0,08880548 ! anion binding GO:0043168 104 90 0,000 0,08753961 0,08878079 ! amine transport GO:0015837 97 90 0,000 0,08753961 0,08875611 ! outer membrane GO:0019867 104 90 0,000 0,08753961 0,08873145 ! extracellular matrix part GO:0044420 111 90 0,000 0,08753961 0,0887068 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 108 91 0,000 0,08847019 0,0896249 ! ribonucleoside triphosphate biosynthetic process GO:0009201 102 91 0,000 0,08847019 0,08960001 GO:0009142|nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 104 91 0,000 0,08847019 0,08957515 ! sulfur metabolic process GO:0006790 98 91 0,000 0,08847019 0,08955029 ! sex differentiation GO:0007548 103 91 0,000 0,08847019 0,08952545 ! hormone metabolic process GO:0042445 107 91 0,000 0,08847019 0,08950062 ! regulation of protein localization GO:0032880 99 91 0,000 0,08847019 0,08947581 ! detection of stimulus GO:0051606 100 91 0,000 0,08847019 0,08945101 ! structure-specific DNA binding GO:0043566 112 92 0,000 0,08939987 0,09036596 ! anatomical structure homeostasis GO:0060249 121 92 0,000 0,08939987 0,09034092 ! carboxylic acid catabolic process GO:0046395 100 92 0,000 0,08939987 0,09031591 GO:0016054|organic acid catabolic process, ! translation factor activity, nucleic acid binding GO:0008135 108 92 0,000 0,08939987 0,0902909 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 111 92 0,000 0,08939987 0,09026591 ! extracellular structure organization GO:0043062 119 92 0,000 0,08939987 0,09024093 ! neurotransmitter receptor activity GO:0030594 104 93 0,000 0,09032866 0,09115323 ! response to nutrient levels GO:0031667 105 93 0,000 0,09032866 0,09112803 ! protein modification by small protein conjugation or removal GO:0070647 112 93 0,000 0,09032866 0,09110283 ! ATPase activity, coupled to transmembrane movement of substances GO:0042626 102 94 0,000 0,09125654 0,09201323 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 104 94 0,000 0,09125654 0,09198781 ! morphogenesis of an epithelium GO:0002009 113 94 0,000 0,09125654 0,0919624 GO:0060429|epithelium development, ! neurotransmitter binding GO:0042165 105 94 0,000 0,09125654 0,091937 ! DNA packaging GO:0006323 113 94 0,000 0,09125654 0,09191162 ! homophilic cell adhesion GO:0007156 107 95 0,000 0,09218354 0,09281963 ! ATPase activity, coupled to movement of substances GO:0043492 104 95 0,000 0,09218354 0,09279402 ! anterior/posterior pattern formation GO:0009952 109 95 0,000 0,09218354 0,09276842 ! immune effector process GO:0002252 110 95 0,000 0,09218354 0,09274284 ! apical plasma membrane GO:0016324 105 95 0,000 0,09218354 0,09271727 ! translational elongation GO:0006414 104 96 0,000 0,09310963 0,09362291 ! hydrolase activity, acting on glycosyl bonds GO:0016798 109 96 0,000 0,09310963 0,09359712 ! in utero embryonic development GO:0001701 110 96 0,000 0,09310963 0,09357133 ! carbohydrate catabolic process GO:0016052 116 96 0,000 0,09310963 0,09354556 ! receptor complex GO:0043235 131 96 0,000 0,09310963 0,0935198 ! regulation of response to external stimulus GO:0032101 109 96 0,000 0,09310963 0,09349406 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 100 96 0,000 0,09310963 0,09346834 ! metalloendopeptidase activity GO:0004222 126 97 0,000 0,09403483 0,09437113 ! perinuclear region of cytoplasm GO:0048471 125 97 0,000 0,09403483 0,09434518 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances GO:0016820 105 97 0,000 0,09403483 0,09431924 ! carboxylic acid binding GO:0031406 108 97 0,000 0,09403483 0,09429331 ! protein maturation GO:0051604 109 97 0,000 0,09403483 0,0942674 ! intermediate filament GO:0005882 102 98 0,000 0,09495914 0,09516784 GO:0045111|intermediate filament cytoskeleton, ! UDP-glycosyltransferase activity GO:0008194 120 98 0,000 0,09495914 0,0951417 ! cell fate commitment GO:0045165 118 98 0,000 0,09495914 0,09511558 ! negative regulation of cellular component organization GO:0051129 132 99 0,000 0,09588255 0,09601415 ! hormone activity GO:0005179 113 99 0,000 0,09588255 0,0959878 ! solute:cation symporter activity GO:0015294 110 99 0,000 0,09588255 0,09596146 ! unfolded protein binding GO:0051082 118 100 0,000 0,09680507 0,09685817 ! regulation of neurogenesis GO:0050767 123 100 0,000 0,09680507 0,09683161 ! peptide receptor activity, G-protein coupled GO:0008528 107 100 0,000 0,09680507 0,09680507