pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/103-0-real-Parker_GPL1390-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL1390.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle organization GO:0007051 30 29 3,000 2,167E-08 7,737E-05 ! microtubule cytoskeleton organization GO:0000226 92 87 4,000 2,652E-08 4,735E-05 ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 2,000 5,864E-08 6,98E-05 ! nuclear export GO:0051168 42 40 3,000 8,277E-08 7,389E-05 ! Ran GTPase binding GO:0008536 10 10 2,000 1,255E-07 8,963E-05 ! G1/S transition of mitotic cell cycle GO:0000082 47 46 3,000 1,472E-07 8,762E-05 ! cyclin-dependent protein kinase regulator activity GO:0016538 11 11 2,000 1,724E-07 8,797E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 51 50 3,000 2,072E-07 9,25E-05 ! mitotic spindle organization GO:0007052 12 12 2,000 2,298E-07 9,117E-05 ! protein serine/threonine kinase inhibitor activity GO:0030291 14 14 2,000 3,797E-07 1,356E-04 ! protein export from nucleus GO:0006611 15 15 2,000 4,743E-07 1,54E-04 ! protein kinase regulator activity GO:0019887 64 64 3,000 5,665E-07 1,686E-04 ! establishment of RNA localization GO:0051236 78 75 3,000 1,076E-06 2,956E-04 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! RNA localization GO:0006403 80 77 3,000 1,196E-06 3,052E-04 ! kinase regulator activity GO:0019207 77 77 3,000 1,196E-06 2,848E-04 ! interphase of mitotic cell cycle GO:0051329 84 82 3,000 1,541E-06 3,44E-04 GO:0051325|interphase, ! androgen receptor binding GO:0050681 23 23 2,000 1,836E-06 3,857E-04 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 92 89 3,000 2,142E-06 4,249E-04 ! RNA export from nucleus GO:0006405 27 25 2,000 2,382E-06 4,476E-04 ! protein kinase inhibitor activity GO:0004860 28 28 2,000 3,385E-06 6,045E-04 ! kinase inhibitor activity GO:0019210 30 30 2,000 4,19E-06 7,125E-04 ! steroid hormone receptor binding GO:0035258 33 33 2,000 5,62E-06 9,122E-04 ! androgen receptor signaling pathway GO:0030521 34 33 2,000 5,62E-06 8,725E-04 ! negative regulation of protein ubiquitination GO:0031397 5 5 1,000 1,104E-05 1,642E-03 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 1,000 1,104E-05 1,576E-03 ! base conversion or substitution editing GO:0016553 5 5 1,000 1,104E-05 1,516E-03 ! induction of apoptosis by intracellular signals GO:0008629 46 43 2,000 1,263E-05 1,67E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 1,654E-05 2,11E-03 ! microtubule nucleation GO:0007020 6 6 1,000 1,654E-05 2,037E-03 ! GDP-dissociation inhibitor activity GO:0005092 6 6 1,000 1,654E-05 1,969E-03 ! response to UV GO:0009411 50 49 2,000 1,878E-05 2,163E-03 ! diphosphotransferase activity GO:0016778 8 7 1,000 2,314E-05 2,583E-03 ! activation of caspase activity by cytochrome c GO:0008635 7 7 1,000 2,314E-05 2,504E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 7 7 1,000 2,314E-05 2,431E-03 GO:0010921|regulation of phosphatase activity, ! regulation of focal adhesion formation GO:0051893 9 7 1,000 2,314E-05 2,361E-03 ! steroid hormone receptor signaling pathway GO:0030518 58 57 2,000 2,966E-05 2,942E-03 ! keratinocyte proliferation GO:0043616 8 8 1,000 3,084E-05 2,976E-03 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 8 8 1,000 3,084E-05 2,898E-03 ! adenosine deaminase activity GO:0004000 8 8 1,000 3,084E-05 2,824E-03 ! negative regulation of protein kinase activity GO:0006469 67 61 2,000 3,639E-05 3,249E-03 ! negative regulation of kinase activity GO:0033673 68 62 2,000 3,821E-05 3,328E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 9 9 1,000 3,963E-05 3,369E-03 ! regulation of S phase of mitotic cell cycle GO:0007090 9 9 1,000 3,963E-05 3,291E-03 ! positive regulation of Rho GTPase activity GO:0032321 9 9 1,000 3,963E-05 3,216E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 64 63 2,000 4,01E-05 3,182E-03 ! nuclear pore GO:0005643 69 65 2,000 4,405E-05 3,419E-03 ! negative regulation of transferase activity GO:0051348 71 65 2,000 4,405E-05 3,347E-03 ! response to unfolded protein GO:0006986 68 66 2,000 4,611E-05 3,431E-03 ! regulation of caspase activity GO:0043281 70 67 2,000 4,824E-05 3,516E-03 ! Ras GTPase binding GO:0017016 70 67 2,000 4,824E-05 3,446E-03 ! nuclear hormone receptor binding GO:0035257 68 67 2,000 4,824E-05 3,378E-03 ! regulation of dephosphorylation GO:0035303 12 10 1,000 4,95E-05 3,399E-03 ! regulation of stress fiber formation GO:0051492 13 10 1,000 4,95E-05 3,335E-03 ! calcium-transporting ATPase activity GO:0005388 12 10 1,000 4,95E-05 3,273E-03 ! regulation of endopeptidase activity GO:0052548 72 69 2,000 5,269E-05 3,421E-03 ! response to protein stimulus GO:0051789 74 72 2,000 5,986E-05 3,817E-03 ! regulation of actin filament bundle formation GO:0032231 14 11 1,000 6,046E-05 3,788E-03 ! positive regulation of B cell proliferation GO:0030890 15 11 1,000 6,046E-05 3,723E-03 ! hormone receptor binding GO:0051427 75 73 2,000 6,239E-05 3,776E-03 ! pore complex GO:0046930 78 74 2,000 6,498E-05 3,867E-03 ! regulation of peptidase activity GO:0052547 78 74 2,000 6,498E-05 3,804E-03 ! small GTPase binding GO:0031267 78 75 2,000 6,764E-05 3,896E-03 ! positive regulation of Ras GTPase activity GO:0032320 12 12 1,000 7,251E-05 4,11E-03 ! negative regulation of caspase activity GO:0043154 12 12 1,000 7,251E-05 4,046E-03 ! GTPase binding GO:0051020 83 80 2,000 8,203E-05 4,507E-03 ! regulation of cell cycle process GO:0010564 84 80 2,000 8,203E-05 4,438E-03 ! regulation of Ras GTPase activity GO:0032318 84 80 2,000 8,203E-05 4,372E-03 ! regulation of S phase GO:0033261 17 13 1,000 8,564E-05 4,497E-03 ! positive regulation of GTPase activity GO:0043547 14 13 1,000 8,564E-05 4,432E-03 ! positive regulation of cell growth GO:0030307 13 13 1,000 8,564E-05 4,369E-03 ! regulation of protein ubiquitination GO:0031396 13 13 1,000 8,564E-05 4,307E-03 ! release of cytochrome c from mitochondria GO:0001836 14 14 1,000 9,985E-05 4,952E-03 ! regulation of B cell proliferation GO:0030888 18 14 1,000 9,985E-05 4,884E-03 ! calcium ion transmembrane transporter activity GO:0015085 16 14 1,000 9,985E-05 4,818E-03 ! skin development GO:0043588 16 15 1,000 1,151E-04 5,482E-03 ! negative regulation of peptidase activity GO:0010466 16 15 1,000 1,151E-04 5,41E-03 ! histone binding GO:0042393 15 15 1,000 1,151E-04 5,34E-03 ! positive regulation of cell size GO:0045793 16 16 1,000 1,315E-04 6,02E-03 ! gene silencing by RNA GO:0031047 16 16 1,000 1,315E-04 5,944E-03 ! regulation of GTPase activity GO:0043087 104 97 2,000 1,456E-04 6,497E-03 ! regulation of Rho GTPase activity GO:0032319 17 17 1,000 1,489E-04 6,566E-03 ! G2/M transition of mitotic cell cycle GO:0000086 17 17 1,000 1,489E-04 6,486E-03 ! DNA fragmentation involved in apoptosis GO:0006309 17 17 1,000 1,489E-04 6,408E-03 ! chromatin binding GO:0003682 102 99 2,000 1,546E-04 6,574E-03 ! chaperone binding GO:0051087 18 18 1,000 1,675E-04 7,035E-03 ! negative regulation of translation GO:0017148 20 18 1,000 1,675E-04 6,953E-03 ! protein import into nucleus, docking GO:0000059 18 18 1,000 1,675E-04 6,873E-03 ! protein phosphatase type 2A complex GO:0000159 20 18 1,000 1,675E-04 6,795E-03 ! cellular response to unfolded protein GO:0034620 21 19 1,000 1,87E-04 7,504E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of cell-matrix adhesion GO:0001952 22 20 1,000 2,077E-04 8,24E-03 GO:0010810|regulation of cell-substrate adhesion, ! apoptotic mitochondrial changes GO:0008637 21 21 1,000 2,294E-04 9,002E-03 ! positive regulation of fibroblast proliferation GO:0048146 22 21 1,000 2,294E-04 8,904E-03 ! cell structure disassembly during apoptosis GO:0006921 21 21 1,000 2,294E-04 8,808E-03 ! positive regulation of cell adhesion GO:0045785 23 22 1,000 2,522E-04 9,58E-03 ! positive regulation of B cell activation GO:0050871 26 22 1,000 2,522E-04 9,479E-03 ! negative regulation of phosphorylation GO:0042326 26 22 1,000 2,522E-04 9,381E-03 ! metallocarboxypeptidase activity GO:0004181 23 22 1,000 2,522E-04 9,284E-03 ! apoptotic nuclear changes GO:0030262 23 23 1,000 2,76E-04 0,01005786 ! negative regulation of phosphorus metabolic process GO:0010563 27 23 1,000 2,76E-04 9,956E-03 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of ARF GTPase activity GO:0032312 26 23 1,000 2,76E-04 9,857E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 24 24 1,000 3,009E-04 0,01063956 ! ARF GTPase activator activity GO:0008060 27 24 1,000 3,009E-04 0,01053525 ! regulation of fibroblast proliferation GO:0048145 25 24 1,000 3,009E-04 0,01043297 ! DNA catabolic process, endonucleolytic GO:0000737 24 24 1,000 3,009E-04 0,01033265 ! negative regulation of protein modification process GO:0031400 28 24 1,000 3,009E-04 0,01023424 ! actin filament GO:0005884 28 25 1,000 3,269E-04 0,01101226 ! regulation of microtubule cytoskeleton organization GO:0070507 27 25 1,000 3,269E-04 0,01090934 ! fat cell differentiation GO:0045444 26 26 1,000 3,539E-04 0,01170161 ! response to endoplasmic reticulum stress GO:0034976 29 26 1,000 3,539E-04 0,01159425 ! cellular response to extracellular stimulus GO:0031668 27 26 1,000 3,539E-04 0,01148885 ! response to heat GO:0009408 26 26 1,000 3,539E-04 0,01138535 ! mitochondrial intermembrane space GO:0005758 28 27 1,000 3,82E-04 0,01217867 ! deaminase activity GO:0019239 27 27 1,000 3,82E-04 0,0120709 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 27 27 1,000 3,82E-04 0,01196501 ! nuclear chromatin GO:0000790 28 27 1,000 3,82E-04 0,01186097 ! ER-nuclear signaling pathway GO:0006984 31 28 1,000 4,111E-04 0,01265522 ! gene silencing GO:0016458 29 29 1,000 4,413E-04 0,01346793 ! negative regulation of hydrolase activity GO:0051346 32 30 1,000 4,725E-04 0,01429858 ! cation-transporting ATPase activity GO:0019829 32 30 1,000 4,725E-04 0,01417843 ! regulation of microtubule-based process GO:0032886 32 30 1,000 4,725E-04 0,01406027 ! condensed nuclear chromosome GO:0000794 32 31 1,000 5,047E-04 0,0148963 ! regulation of B cell activation GO:0050864 36 32 1,000 5,381E-04 0,01574917 ! double-stranded RNA binding GO:0003725 33 32 1,000 5,381E-04 0,01562112 ! organelle envelope lumen GO:0031970 34 33 1,000 5,724E-04 0,01648439 ! carboxypeptidase activity GO:0004180 35 34 1,000 6,078E-04 0,01736355 ! response to calcium ion GO:0051592 39 35 1,000 6,442E-04 0,01825817 ! metalloexopeptidase activity GO:0008235 36 35 1,000 6,442E-04 0,0181144 ! protein serine/threonine phosphatase complex GO:0008287 38 35 1,000 6,442E-04 0,01797288 ! regulation of ARF protein signal transduction GO:0032012 40 35 1,000 6,442E-04 0,01783356 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 37 35 1,000 6,442E-04 0,01769638 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 38 36 1,000 6,817E-04 0,01858254 ! positive regulation of leukocyte proliferation GO:0070665 40 36 1,000 6,817E-04 0,01844176 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 40 38 1,000 7,597E-04 0,02039809 ! RNA modification GO:0009451 39 38 1,000 7,597E-04 0,02024587 ! positive regulation of cell cycle GO:0045787 39 39 1,000 8,003E-04 0,02116876 ! protein serine/threonine phosphatase activity GO:0004722 42 40 1,000 8,419E-04 0,02210506 ! nucleus organization GO:0006997 40 40 1,000 8,419E-04 0,02194371 ! response to insulin stimulus GO:0032868 45 40 1,000 8,419E-04 0,0217847 ! regulation of translational initiation GO:0006446 41 41 1,000 8,845E-04 0,02272271 ! positive regulation of growth GO:0045927 42 42 1,000 9,281E-04 0,02367343 ! keratinocyte differentiation GO:0030216 46 43 1,000 9,728E-04 0,02463655 ! cellular component disassembly GO:0022411 45 44 1,000 1,018E-03 0,02561174 ! regulation of mast cell proliferation GO:0070666 48 44 1,000 1,018E-03 0,02543264 ! response to temperature stimulus GO:0009266 45 45 1,000 1,065E-03 0,026414 ! nuclear matrix GO:0016363 49 46 1,000 1,113E-03 0,02740684 ! activation of caspase activity GO:0006919 49 46 1,000 1,113E-03 0,02721912 ! regulation of leukocyte proliferation GO:0070663 50 46 1,000 1,113E-03 0,02703395 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epidermal cell differentiation GO:0009913 51 48 1,000 1,211E-03 0,029227 ! protein N-terminus binding GO:0047485 51 48 1,000 1,211E-03 0,02903084 ! positive regulation of organelle organization GO:0010638 49 49 1,000 1,262E-03 0,0300454 ! lamellipodium GO:0030027 53 49 1,000 1,262E-03 0,02984642 ! nuclear periphery GO:0034399 53 50 1,000 1,314E-03 0,03086595 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 56 51 1,000 1,367E-03 0,03189562 ! steroid hormone receptor activity GO:0003707 53 51 1,000 1,367E-03 0,0316885 ! DNA damage response, signal transduction GO:0042770 58 52 1,000 1,42E-03 0,03272271 ! positive regulation of caspase activity GO:0043280 55 52 1,000 1,42E-03 0,03251295 GO:0010952|positive regulation of peptidase activity, ! positive regulation of protein amino acid phosphorylation GO:0001934 54 52 1,000 1,42E-03 0,03230586 ! nucleoside metabolic process GO:0009116 61 53 1,000 1,475E-03 0,03333916 ! regulation of protein catabolic process GO:0042176 57 54 1,000 1,531E-03 0,03438193 ! DNA catabolic process GO:0006308 55 54 1,000 1,531E-03 0,03416704 ! response to peptide hormone stimulus GO:0043434 60 55 1,000 1,588E-03 0,03521385 ! regulation of mitosis GO:0007088 56 56 1,000 1,645E-03 0,03626969 GO:0051783|regulation of nuclear division, ! positive regulation of phosphorylation GO:0042327 59 57 1,000 1,704E-03 0,03733435 ! positive regulation of phosphorus metabolic process GO:0010562 61 58 1,000 1,764E-03 0,03840763 GO:0045937|positive regulation of phosphate metabolic process, ! ligand-dependent nuclear receptor activity GO:0004879 65 62 1,000 2,013E-03 0,04356092 ! mitochondrial respiratory chain GO:0005746 65 63 1,000 2,077E-03 0,04468984 ! respiratory chain GO:0070469 66 64 1,000 2,143E-03 0,04582622 ! negative regulation of cell growth GO:0030308 68 65 1,000 2,21E-03 0,04696986 ! response to metal ion GO:0010038 69 65 1,000 2,21E-03 0,04669193 ! positive regulation of protein modification process GO:0031401 69 65 1,000 2,21E-03 0,04641727 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 71 66 1,000 2,277E-03 0,04755779 ! negative regulation of cell size GO:0045792 70 67 1,000 2,346E-03 0,04870528 ! mRNA transport GO:0051028 70 67 1,000 2,346E-03 0,04842375 ! positive regulation of lymphocyte activation GO:0051251 72 67 1,000 2,346E-03 0,04814545 ! protein import into nucleus GO:0006606 72 68 1,000 2,415E-03 0,04928976 ! regulation of actin cytoskeleton organization GO:0032956 74 68 1,000 2,415E-03 0,04900971 ! focal adhesion GO:0005925 75 69 1,000 2,486E-03 0,05015579 ! nuclear import GO:0051170 74 70 1,000 2,558E-03 0,05130844 ! response to inorganic substance GO:0010035 74 70 1,000 2,558E-03 0,0510218 ! cell cortex GO:0005938 74 70 1,000 2,558E-03 0,05073834 ! regulation of actin filament-based process GO:0032970 77 71 1,000 2,63E-03 0,05188774 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 75 71 1,000 2,63E-03 0,05160265 ! cell-substrate adherens junction GO:0005924 78 72 1,000 2,703E-03 0,05275359 ! exopeptidase activity GO:0008238 78 73 1,000 2,778E-03 0,05391072 ! protein localization in nucleus GO:0034504 78 74 1,000 2,853E-03 0,0550739 ! regulation of Rho protein signal transduction GO:0035023 79 74 1,000 2,853E-03 0,0547778 ! nuclear chromosome part GO:0044454 76 74 1,000 2,853E-03 0,05448487 ! regulation of catabolic process GO:0009894 80 75 1,000 2,929E-03 0,05564465 ! cell-substrate junction GO:0030055 82 75 1,000 2,929E-03 0,05535024 ! positive regulation of cell activation GO:0050867 80 75 1,000 2,929E-03 0,05505892 GO:0002696|positive regulation of leukocyte activation, ! regulation of cell adhesion GO:0030155 82 78 1,000 3,164E-03 0,05915839 ! negative regulation of growth GO:0045926 84 80 1,000 3,325E-03 0,06184876 ! ATP biosynthetic process GO:0006754 85 80 1,000 3,325E-03 0,0615283 ! condensed chromosome GO:0000793 82 80 1,000 3,325E-03 0,06121115 ! protein kinase binding GO:0019901 89 80 1,000 3,325E-03 0,06089725 ! protein transporter activity GO:0008565 85 82 1,000 3,49E-03 0,06359292 ! mitochondrion organization GO:0007005 86 83 1,000 3,574E-03 0,06479136 ! cell leading edge GO:0031252 90 83 1,000 3,574E-03 0,06446413 ! cellular respiration GO:0045333 85 85 1,000 3,745E-03 0,0672028 ! pigment granule GO:0048770 90 86 1,000 3,832E-03 0,06841559 GO:0042470|melanosome, ! spindle GO:0005819 89 87 1,000 3,919E-03 0,06963295 ! cell cycle arrest GO:0007050 92 87 1,000 3,919E-03 0,06928823 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 95 90 1,000 4,188E-03 0,0736726 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! adherens junction GO:0005912 96 90 1,000 4,188E-03 0,07331146 ! ATP metabolic process GO:0046034 96 91 1,000 4,279E-03 0,07454612 ! ribonucleoside triphosphate biosynthetic process GO:0009201 97 91 1,000 4,279E-03 0,07418425 ! nucleoside triphosphate biosynthetic process GO:0009142 98 92 1,000 4,372E-03 0,07541876 ! protein tyrosine phosphatase activity GO:0004725 104 92 1,000 4,372E-03 0,07505617 ! regulation of lymphocyte activation GO:0051249 100 95 1,000 4,654E-03 0,07952473 ! response to virus GO:0009615 102 95 1,000 4,654E-03 0,07914604 ! Wnt receptor signaling pathway GO:0016055 104 96 1,000 4,75E-03 0,08039609 ! microtubule associated complex GO:0005875 104 97 1,000 4,847E-03 0,08164981 ! anchoring junction GO:0070161 103 97 1,000 4,847E-03 0,08126648 ! nuclear chromosome GO:0000228 102 99 1,000 5,044E-03 0,08416793 ! regulation of cellular component biogenesis GO:0044087 106 99 1,000 5,044E-03 0,08377645 ! kinase binding GO:0019900 108 99 1,000 5,044E-03 0,0833886 ! Ras protein signal transduction GO:0007265 105 99 1,000 5,044E-03 0,08300432 ! electron transport chain GO:0022900 102 100 1,000 5,144E-03 0,0842565 ! protein polymerization GO:0051258 114 100 1,000 5,144E-03 0,08387177 ! tRNA transcription GO:0009304 5 5 0,000 5,419E-03 0,08795329 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 5 5 0,000 5,419E-03 0,08755531 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 5,419E-03 0,08716092 ! benzene and derivative metabolic process GO:0042537 5 5 0,000 5,419E-03 0,08677006 ! response to oxygen radical GO:0000305 5 5 0,000 5,419E-03 0,0863827 ! positive regulation of axon extension GO:0045773 6 5 0,000 5,419E-03 0,08599877 ! negative regulation of bone resorption GO:0045779 5 5 0,000 5,419E-03 0,08561825 ! positive regulation of lipid biosynthetic process GO:0046889 5 5 0,000 5,419E-03 0,08524108 ! regulation of interferon-beta production GO:0032648 6 5 0,000 5,419E-03 0,08486721 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! sodium-independent organic anion transmembrane transporter activity GO:0015347 6 5 0,000 5,419E-03 0,08449661 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 5,419E-03 0,08412924 ! negative regulation of transmembrane transport GO:0034763 5 5 0,000 5,419E-03 0,08376504 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! hypothalamus development GO:0021854 5 5 0,000 5,419E-03 0,08340398 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 5,419E-03 0,08304603 ! N-terminal protein lipidation GO:0006498 5 5 0,000 5,419E-03 0,08269113 ! glycolipid transport GO:0046836 5 5 0,000 5,419E-03 0,08233925 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 5 5 0,000 5,419E-03 0,08199036 ! phosphoinositide 3-kinase binding GO:0043548 5 5 0,000 5,419E-03 0,08164441 ! protein amino acid sulfation GO:0006477 5 5 0,000 5,419E-03 0,08130136 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 6 5 0,000 5,419E-03 0,08096119 ! embryonic camera-type eye development GO:0031076 7 5 0,000 5,419E-03 0,08062385 GO:0048596|embryonic camera-type eye morphogenesis, ! opioid peptide activity GO:0001515 5 5 0,000 5,419E-03 0,08028931 ! selenocysteine incorporation GO:0001514 5 5 0,000 5,419E-03 0,07995754 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 5 5 0,000 5,419E-03 0,0796285 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 5 5 0,000 5,419E-03 0,07930215 ! elastic fiber assembly GO:0048251 5 5 0,000 5,419E-03 0,07897847 ! regulation of mitochondrial membrane permeability GO:0046902 5 5 0,000 5,419E-03 0,07865742 ! neurofilament cytoskeleton organization GO:0060052 5 5 0,000 5,419E-03 0,07833896 ! ruffle membrane GO:0032587 5 5 0,000 5,419E-03 0,07802308 ! regulation of histone modification GO:0031056 5 5 0,000 5,419E-03 0,07770974 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 5,419E-03 0,0773989 ! behavioral response to pain GO:0048266 5 5 0,000 5,419E-03 0,07709054 ! clathrin coat assembly GO:0048268 6 5 0,000 5,419E-03 0,07678462 ! Notch receptor processing GO:0007220 5 5 0,000 5,419E-03 0,07648112 ! cerebral cortex radially oriented cell migration GO:0021799 5 5 0,000 5,419E-03 0,07618002 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 6 5 0,000 5,419E-03 0,07588127 ! serotonin receptor signaling pathway GO:0007210 5 5 0,000 5,419E-03 0,07558486 ! oxidoreductase activity, oxidizing metal ions GO:0016722 5 5 0,000 5,419E-03 0,07529076 ! response to lipid GO:0033993 5 5 0,000 5,419E-03 0,07499893 ! cytoplasmic dynein complex GO:0005868 6 5 0,000 5,419E-03 0,07470936 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 5,419E-03 0,07442202 ! positive regulation of muscle cell differentiation GO:0051149 5 5 0,000 5,419E-03 0,07413687 ! smooth muscle cell differentiation GO:0051145 5 5 0,000 5,419E-03 0,07385391 ! exo-alpha-sialidase activity GO:0004308 5 5 0,000 5,419E-03 0,0735731 GO:0016997|alpha-sialidase activity, ! regulation of odontogenesis GO:0042481 5 5 0,000 5,419E-03 0,07329441 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 5,419E-03 0,07301783 ! formate-tetrahydrofolate ligase activity GO:0004329 5 5 0,000 5,419E-03 0,07274332 ! negative regulation of heart contraction GO:0045822 5 5 0,000 5,419E-03 0,07247088 ! ovulation from ovarian follicle GO:0001542 5 5 0,000 5,419E-03 0,07220046 ! DNA ligation during DNA repair GO:0051103 5 5 0,000 5,419E-03 0,07193206 ! 1-acylglycerophosphocholine O-acyltransferase activity GO:0047184 5 5 0,000 5,419E-03 0,07166565 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 5,419E-03 0,0714012 ! negative regulation of endocytosis GO:0045806 5 5 0,000 5,419E-03 0,07113869 ! microfibril GO:0001527 5 5 0,000 5,419E-03 0,07087811 GO:0043205|fibril, ! parathyroid gland development GO:0060017 5 5 0,000 5,419E-03 0,07061943 ! toxin metabolic process GO:0009404 5 5 0,000 5,419E-03 0,07036263 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 5,419E-03 0,0701077 ! cytokine secretion GO:0050663 5 5 0,000 5,419E-03 0,0698546 ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 5 5 0,000 5,419E-03 0,06960332 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 5,419E-03 0,06935385 ! skeletal myofibril assembly GO:0014866 5 5 0,000 5,419E-03 0,06910616 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 5 0,000 5,419E-03 0,06886023 ! epithelial cell proliferation GO:0050673 5 5 0,000 5,419E-03 0,06861604 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 5 5 0,000 5,419E-03 0,06837358 ! regulation of retroviral genome replication GO:0045091 5 5 0,000 5,419E-03 0,06813283 ! negative regulation of survival gene product expression GO:0008634 5 5 0,000 5,419E-03 0,06789377 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 5,419E-03 0,06765638 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of defense response to virus by host GO:0050691 5 5 0,000 5,419E-03 0,06742064 ! transmembrane-ephrin receptor activity GO:0005005 5 5 0,000 5,419E-03 0,06718654 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 5,419E-03 0,06695406 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 5,419E-03 0,06672319 ! glutamate catabolic process GO:0006538 6 5 0,000 5,419E-03 0,0664939 ! positive regulation of isotype switching to IgG isotypes GO:0048304 9 5 0,000 5,419E-03 0,06626618 ! microvillus organization GO:0032528 5 5 0,000 5,419E-03 0,06604001 GO:0030033|microvillus assembly, ! tyrosine catabolic process GO:0006572 5 5 0,000 5,419E-03 0,06581539 ! L-serine biosynthetic process GO:0006564 5 5 0,000 5,419E-03 0,06559229 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 5,419E-03 0,06537069 ! pericentriolar material GO:0000242 6 5 0,000 5,419E-03 0,06515059 ! polyol biosynthetic process GO:0046173 5 5 0,000 5,419E-03 0,06493196 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 6 5 0,000 5,419E-03 0,0647148 ! platelet-derived growth factor alpha-receptor activity GO:0005018 5 5 0,000 5,419E-03 0,06449908 ! proton-transporting V-type ATPase, V0 domain GO:0033179 5 5 0,000 5,419E-03 0,0642848 ! fibroblast growth factor receptor activity GO:0005007 5 5 0,000 5,419E-03 0,06407193 ! protein-DNA loading ATPase activity GO:0033170 5 5 0,000 5,419E-03 0,06386048 GO:0003689|DNA clamp loader activity, ! insulin-like growth factor receptor activity GO:0005010 5 5 0,000 5,419E-03 0,06365041 ! response to tumor necrosis factor GO:0034612 6 5 0,000 5,419E-03 0,06344172 ! mRNA transcription GO:0009299 6 5 0,000 5,419E-03 0,06323439 ! response to ATP GO:0033198 5 5 0,000 5,419E-03 0,06302842 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 5 5 0,000 5,419E-03 0,06282378 ! adenosine receptor activity, G-protein coupled GO:0001609 5 5 0,000 5,419E-03 0,06262047 ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 5,419E-03 0,06241847 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 5 5 0,000 5,419E-03 0,06221776 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 5,419E-03 0,06201835 ! multivesicular body GO:0005771 5 5 0,000 5,419E-03 0,06182021 ! positive regulation of transporter activity GO:0032411 5 5 0,000 5,419E-03 0,06162333 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 5 5 0,000 5,419E-03 0,0614277 ! forebrain neuron development GO:0021884 6 5 0,000 5,419E-03 0,0612333 ! insulin-like growth factor I binding GO:0031994 5 5 0,000 5,419E-03 0,06104014 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 5 5 0,000 5,419E-03 0,06084819 ! demethylase activity GO:0032451 5 5 0,000 5,419E-03 0,06065744 ! peptidyl-histidine phosphorylation GO:0018106 5 5 0,000 5,419E-03 0,06046789 ! epithelial cell maturation GO:0002070 5 5 0,000 5,419E-03 0,06027951 ! nitric-oxide synthase regulator activity GO:0030235 5 5 0,000 5,419E-03 0,06009231 ! regulation of immunoglobulin secretion GO:0051023 5 5 0,000 5,419E-03 0,05990627 ! zymogen granule GO:0042588 5 5 0,000 5,419E-03 0,05972137 ! guanylate cyclase regulator activity GO:0030249 5 5 0,000 5,419E-03 0,05953761 GO:0010851|cyclase regulator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 5,419E-03 0,05935498 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,419E-03 0,05917347 ! early endosome to late endosome transport GO:0045022 5 5 0,000 5,419E-03 0,05899306 ! positive regulation of translational initiation GO:0045948 5 5 0,000 5,419E-03 0,05881375 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 5,419E-03 0,05863553 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 5,419E-03 0,05845838 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! semaphorin receptor activity GO:0017154 6 5 0,000 5,419E-03 0,0582823 ! proteoglycan binding GO:0043394 9 5 0,000 5,419E-03 0,05810728 ! regulation of collagen metabolic process GO:0010712 6 5 0,000 5,419E-03 0,05793331 ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 6 5 0,000 5,419E-03 0,05776037 ! zinc ion homeostasis GO:0055069 5 5 0,000 5,419E-03 0,05758847 GO:0006882|cellular zinc ion homeostasis, ! deoxyribonucleoside metabolic process GO:0009120 6 5 0,000 5,419E-03 0,05741758 ! nucleoside monophosphate catabolic process GO:0009125 5 5 0,000 5,419E-03 0,05724771 ! activated T cell proliferation GO:0050798 6 5 0,000 5,419E-03 0,05707883 ! advanced glycation end-product receptor activity GO:0050785 5 5 0,000 5,419E-03 0,05691095 ! dynein binding GO:0045502 5 5 0,000 5,419E-03 0,05674406 ! regulation of dendrite development GO:0050773 5 5 0,000 5,419E-03 0,05657814 ! cardiac muscle cell development GO:0055013 5 5 0,000 5,419E-03 0,05641319 ! anterograde axon cargo transport GO:0008089 5 5 0,000 5,419E-03 0,0562492 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,419E-03 0,05608616 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 5,419E-03 0,05592406 GO:0003923|GPI-anchor transamidase activity, ! lymphoid progenitor cell differentiation GO:0002320 5 5 0,000 5,419E-03 0,05576289 ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 5,419E-03 0,05560266 ! MutLalpha complex binding GO:0032405 6 5 0,000 5,419E-03 0,05544334 ! sphingomyelin catabolic process GO:0006685 6 5 0,000 5,419E-03 0,05528493 ! high-density lipoprotein binding GO:0008035 5 5 0,000 5,419E-03 0,05512742 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 5,419E-03 0,05497081 ! positive regulation of B cell differentiation GO:0045579 5 5 0,000 5,419E-03 0,05481508 ! regulation of acetylcholine secretion GO:0014056 5 5 0,000 5,419E-03 0,05466024 ! centromeric DNA binding GO:0019237 5 5 0,000 5,419E-03 0,05450627 ! cyclohydrolase activity GO:0019238 5 5 0,000 5,419E-03 0,05435316 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 5,419E-03 0,05420091 ! positive T cell selection GO:0043368 9 5 0,000 5,419E-03 0,05404951 ! neural tube patterning GO:0021532 5 5 0,000 5,419E-03 0,05389895 ! amylase activity GO:0016160 5 5 0,000 5,419E-03 0,05374923 ! metaphase plate congression GO:0051310 5 5 0,000 5,419E-03 0,05360034 ! regulation of sterol transport GO:0032371 5 5 0,000 5,419E-03 0,05345228 GO:0032374|regulation of cholesterol transport, ! sympathetic nervous system development GO:0048485 5 5 0,000 5,419E-03 0,05330503 ! oxygen homeostasis GO:0032364 5 5 0,000 5,419E-03 0,05315858 ! skeletal muscle regeneration GO:0043403 5 5 0,000 5,419E-03 0,05301294 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 5 5 0,000 5,419E-03 0,0528681 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 5 5 0,000 5,419E-03 0,05272404 ! SAP kinase activity GO:0016909 5 5 0,000 5,419E-03 0,05258077 ! positive regulation of pseudopodium assembly GO:0031274 5 5 0,000 5,419E-03 0,05243828 GO:0031272|regulation of pseudopodium assembly, ! phosphatidylserine binding GO:0001786 5 5 0,000 5,419E-03 0,05229655 ! alpha-mannosidase activity GO:0004559 6 5 0,000 5,419E-03 0,05215559 ! alpha-glucosidase activity GO:0004558 6 5 0,000 5,419E-03 0,05201539 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 5,419E-03 0,05187594 ! myeloid dendritic cell activation GO:0001773 5 5 0,000 5,419E-03 0,05173723 GO:0043011|myeloid dendritic cell differentiation, ! anaphase GO:0051322 5 5 0,000 5,419E-03 0,05159926 GO:0000090|mitotic anaphase, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 5,419E-03 0,05146203 ! ribonuclease H activity GO:0004523 5 5 0,000 5,419E-03 0,05132553 ! CARD domain binding GO:0050700 5 5 0,000 5,419E-03 0,05118975 ! regulation of muscle cell apoptosis GO:0010660 5 5 0,000 5,419E-03 0,05105468 ! AP-2 adaptor complex GO:0030122 5 5 0,000 5,419E-03 0,05092033 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 5 5 0,000 5,419E-03 0,05078668 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 5,419E-03 0,05065373 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 5,419E-03 0,05052147 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 5,419E-03 0,05038991 ! negative regulation of macrophage differentiation GO:0045650 5 5 0,000 5,419E-03 0,05025902 ! negative regulation of osteoclast differentiation GO:0045671 5 5 0,000 5,419E-03 0,05012882 ! ceramidase activity GO:0017040 5 5 0,000 5,419E-03 0,04999929 ! negative regulation of osteoblast differentiation GO:0045668 6 5 0,000 5,419E-03 0,04987042 ! GTP-Rho binding GO:0017049 5 5 0,000 5,419E-03 0,04974222 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 5,419E-03 0,04961468 ! chondroitin sulfotransferase activity GO:0034481 5 5 0,000 5,419E-03 0,04948779 ! positive regulation of T-helper 2 cell differentiation GO:0045630 5 5 0,000 5,419E-03 0,04936154 ! alcohol transmembrane transporter activity GO:0015665 5 5 0,000 5,419E-03 0,04923594 GO:0015166|polyol transmembrane transporter activity, ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 5,419E-03 0,04911098 ! TAP complex GO:0042825 5 5 0,000 5,419E-03 0,04898664 ! bHLH transcription factor binding GO:0043425 5 5 0,000 5,419E-03 0,04886294 ! actinin binding GO:0042805 6 5 0,000 5,419E-03 0,04873986 ! secretory granule organization GO:0033363 5 5 0,000 5,419E-03 0,0486174 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 5 5 0,000 5,419E-03 0,04849555 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 5,419E-03 0,04837431 ! striatum development GO:0021756 5 5 0,000 5,419E-03 0,04825368 ! photoreceptor inner segment GO:0001917 5 5 0,000 5,419E-03 0,04813364 ! regulation of T cell mediated cytotoxicity GO:0001914 9 5 0,000 5,419E-03 0,0480142 ! aldehyde-lyase activity GO:0016832 5 5 0,000 5,419E-03 0,04789536 ! regulation of mitochondrial depolarization GO:0051900 5 5 0,000 5,419E-03 0,0477771 ! T cell activation during immune response GO:0002286 5 5 0,000 5,419E-03 0,04765942 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 5,419E-03 0,04754232 ! 1-aminocyclopropane-1-carboxylate synthase activity GO:0016847 5 5 0,000 5,419E-03 0,04742579 ! dystroglycan complex GO:0016011 6 5 0,000 5,419E-03 0,04730984 ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 5 5 0,000 5,419E-03 0,04719445 ! neural plate development GO:0001840 5 5 0,000 5,419E-03 0,04707962 ! toll-like receptor signaling pathway GO:0002224 5 5 0,000 5,419E-03 0,04696535 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 5,419E-03 0,04685163 ! phosphopantetheine binding GO:0031177 5 5 0,000 5,419E-03 0,04673846 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 5,419E-03 0,04662584 ! negative regulation of actin filament bundle formation GO:0032232 8 5 0,000 5,419E-03 0,04651376 GO:0051497|negative regulation of stress fiber formation, ! organ or tissue specific immune response GO:0002251 5 5 0,000 5,419E-03 0,04640222 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 5,419E-03 0,04629121 ! diacylglycerol metabolic process GO:0046339 5 5 0,000 5,419E-03 0,04618073 ! cytoplasmic microtubule organization GO:0031122 5 5 0,000 5,419E-03 0,04607077 ! retina homeostasis GO:0001895 5 5 0,000 5,419E-03 0,04596134 ! release of sequestered calcium ion into cytosol GO:0051209 10 5 0,000 5,419E-03 0,04585243 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 5 5 0,000 5,419E-03 0,04574403 ! regulation of growth hormone secretion GO:0060123 6 5 0,000 5,419E-03 0,04563614 ! collagen type IV GO:0005587 5 5 0,000 5,419E-03 0,04552876 ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 5,419E-03 0,04542189 ! testosterone 17-beta-dehydrogenase (NADP+) activity GO:0047045 5 5 0,000 5,419E-03 0,04531551 ! retrograde protein transport, ER to cytosol GO:0030970 5 5 0,000 5,419E-03 0,04520964 ! spindle assembly GO:0051225 5 5 0,000 5,419E-03 0,04510425 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 5,419E-03 0,04499936 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 5 5 0,000 5,419E-03 0,04489495 GO:0022011|myelination in the peripheral nervous system, ! drug metabolic process GO:0017144 5 5 0,000 5,419E-03 0,04479103 ! protein amino acid prenylation GO:0018346 5 5 0,000 5,419E-03 0,04468759 ! stem cell division GO:0017145 5 5 0,000 5,419E-03 0,04458462 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 5,419E-03 0,04448212 ! phospholipid scrambling GO:0017121 5 5 0,000 5,419E-03 0,0443801 GO:0017128|phospholipid scramblase activity, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 5 5 0,000 5,419E-03 0,04427855 ! regulation of humoral immune response GO:0002920 9 5 0,000 5,419E-03 0,04417745 ! H3/H4 histone acetyltransferase activity GO:0004406 5 5 0,000 5,419E-03 0,04407682 ! regulation of interferon-alpha biosynthetic process GO:0045354 6 5 0,000 5,419E-03 0,04397665 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 5,419E-03 0,04387693 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of cAMP biosynthetic process GO:0030819 5 5 0,000 5,419E-03 0,04377766 GO:0030816|positive regulation of cAMP metabolic process, ! phagocytic vesicle GO:0045335 5 5 0,000 5,419E-03 0,04367884 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 5,419E-03 0,04358046 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 5,419E-03 0,04348253 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 5,419E-03 0,04338503 ! polyol transport GO:0015791 6 5 0,000 5,419E-03 0,04328797 ! cell adhesion mediated by integrin GO:0033627 6 5 0,000 5,419E-03 0,04319135 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 5,419E-03 0,04309515 ! glycerol-3-phosphate metabolic process GO:0006072 5 5 0,000 5,419E-03 0,04299939 ! platelet activating factor metabolic process GO:0046469 5 5 0,000 5,419E-03 0,04290405 ! cobalt ion transport GO:0006824 5 5 0,000 5,419E-03 0,04280912 ! response to zinc ion GO:0010043 5 5 0,000 5,419E-03 0,04271462 ! poly(U) RNA binding GO:0008266 5 5 0,000 5,419E-03 0,04262054 ! negative regulation of cell-cell adhesion GO:0022408 5 5 0,000 5,419E-03 0,04252687 ! adaptation of signaling pathway GO:0022401 5 5 0,000 5,419E-03 0,04243361 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! glucocorticoid receptor signaling pathway GO:0042921 5 5 0,000 5,419E-03 0,04234075 GO:0031958|corticosteroid receptor signaling pathway, ! regulation of gluconeogenesis GO:0006111 5 5 0,000 5,419E-03 0,04224831 ! sensory perception of bitter taste GO:0050913 5 5 0,000 5,419E-03 0,04215626 ! regulation of dopamine uptake GO:0051584 5 5 0,000 5,419E-03 0,04206462 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! opsonization GO:0008228 5 5 0,000 5,419E-03 0,04197337 ! protein maturation by protein folding GO:0022417 5 5 0,000 5,419E-03 0,04188252 ! neuron remodeling GO:0016322 6 5 0,000 5,419E-03 0,04179206 ! neurexin binding GO:0042043 5 5 0,000 5,419E-03 0,04170199 ! sensory perception of temperature stimulus GO:0050951 5 5 0,000 5,419E-03 0,04161231 ! regulation of potassium ion transport GO:0043266 5 5 0,000 5,419E-03 0,04152301 ! low-density lipoprotein particle GO:0034362 5 5 0,000 5,419E-03 0,0414341 ! chemoattractant activity GO:0042056 5 5 0,000 5,419E-03 0,04134556 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 6 5 0,000 5,419E-03 0,04125741 ! lipoic acid binding GO:0031405 5 5 0,000 5,419E-03 0,04116963 ! lithium ion binding GO:0031403 6 5 0,000 5,419E-03 0,04108222 ! lipoprotein particle clearance GO:0034381 5 5 0,000 5,419E-03 0,04099518 ! grooming behavior GO:0007625 5 5 0,000 5,419E-03 0,04090851 ! sequestering of actin monomers GO:0042989 5 5 0,000 5,419E-03 0,0408222 ! cobalamin binding GO:0031419 5 5 0,000 5,419E-03 0,04073626 ! retinoic acid binding GO:0001972 5 5 0,000 5,419E-03 0,04065068 ! response to axon injury GO:0048678 5 5 0,000 5,419E-03 0,04056546 ! regulation of activin receptor signaling pathway GO:0032925 5 5 0,000 5,419E-03 0,04048059 ! positive regulation of neurotransmitter secretion GO:0001956 5 5 0,000 5,419E-03 0,04039608 ! mitochondrial genome maintenance GO:0000002 5 5 0,000 5,419E-03 0,04031193 ! protein-lysine 6-oxidase activity GO:0004720 6 5 0,000 5,419E-03 0,04022812 ! female pronucleus GO:0001939 5 5 0,000 5,419E-03 0,04014466 ! F-actin capping protein complex GO:0008290 5 5 0,000 5,419E-03 0,04006154 ! DNA topoisomerase activity GO:0003916 5 5 0,000 5,419E-03 0,03997877 ! poly(ADP-ribose) glycohydrolase activity GO:0004649 6 5 0,000 5,419E-03 0,03989634 ! spinal cord dorsal/ventral patterning GO:0021513 5 5 0,000 5,419E-03 0,03981425 ! dorsal spinal cord development GO:0021516 5 5 0,000 5,419E-03 0,03973249 ! ceramide catabolic process GO:0046514 5 5 0,000 5,419E-03 0,03965107 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 5,419E-03 0,03956999 ! neutrophil mediated immunity GO:0002446 5 5 0,000 5,419E-03 0,03948923 ! regulation of oligodendrocyte differentiation GO:0048713 5 5 0,000 5,419E-03 0,03940881 ! Rap GTPase activator activity GO:0046582 5 5 0,000 5,419E-03 0,03932871 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 6 5 0,000 5,419E-03 0,03924893 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 5 5 0,000 5,419E-03 0,03916948 ! positive regulation of filopodium assembly GO:0051491 5 5 0,000 5,419E-03 0,03909035 GO:0051489|regulation of filopodium assembly, ! heart trabecula formation GO:0060347 5 5 0,000 5,419E-03 0,03901154 GO:0060343|trabecula formation, ! amine oxidase activity GO:0008131 6 5 0,000 5,419E-03 0,03893305 ! neutrophil activation GO:0042119 5 5 0,000 5,419E-03 0,03885487 ! regulation of response to food GO:0032095 5 5 0,000 5,419E-03 0,038777 ! response to food GO:0032094 5 5 0,000 5,419E-03 0,03869945 ! hedgehog receptor activity GO:0008158 5 5 0,000 5,419E-03 0,0386222 ! protein phosphatase 1 binding GO:0008157 5 5 0,000 5,419E-03 0,03854527 ! lipoprotein catabolic process GO:0042159 5 5 0,000 5,419E-03 0,03846864 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 5,419E-03 0,03839231 ! organ growth GO:0035265 7 5 0,000 5,419E-03 0,03831629 ! positive regulation of multicellular organismal metabolic process GO:0044253 6 5 0,000 5,419E-03 0,03824056 ! small-subunit processome GO:0032040 5 5 0,000 5,419E-03 0,03816514 ! UDP-glucosyltransferase activity GO:0035251 5 5 0,000 5,419E-03 0,03809001 ! myosin heavy chain binding GO:0032036 5 5 0,000 5,419E-03 0,03801518 ! nucleoside salvage GO:0043174 7 5 0,000 5,419E-03 0,03794064 GO:0006166|purine ribonucleoside salvage, ! nucleobase transport GO:0015851 5 5 0,000 5,419E-03 0,03786639 ! GPI anchor binding GO:0034235 6 5 0,000 5,419E-03 0,03779243 ! thrombin receptor activity GO:0015057 5 5 0,000 5,419E-03 0,03771876 ! nucleotide-excision repair complex GO:0000109 6 5 0,000 5,419E-03 0,03764538 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 5 5 0,000 5,419E-03 0,03757228 ! dendritic shaft GO:0043198 5 5 0,000 5,419E-03 0,03749947 ! terminal button GO:0043195 8 5 0,000 5,419E-03 0,03742693 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 5,419E-03 0,03735468 GO:0016274|protein-arginine N-methyltransferase activity, ! ferrous iron binding GO:0008198 6 5 0,000 5,419E-03 0,03728271 ! eukaryotic initiation factor 4E binding GO:0008190 5 5 0,000 5,419E-03 0,03721101 ! G2/M transition checkpoint GO:0031576 5 5 0,000 5,419E-03 0,03713959 GO:0031572|G2/M transition DNA damage checkpoint, ! negative regulation of peptide secretion GO:0002792 6 5 0,000 5,419E-03 0,03706844 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 5 5 0,000 5,419E-03 0,03699756 ! response to UV-C GO:0010225 5 5 0,000 5,419E-03 0,03692695 ! carbonyl reductase (NADPH) activity GO:0004090 5 5 0,000 5,419E-03 0,03685662 ! regulation of alpha-beta T cell proliferation GO:0046640 9 5 0,000 5,419E-03 0,03678655 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! positive regulation of organ growth GO:0046622 5 5 0,000 5,419E-03 0,03671674 ! 1-alkyl-2-acetylglycerophosphocholine esterase activity GO:0003847 5 5 0,000 5,419E-03 0,03664721 ! IgE binding GO:0019863 5 5 0,000 5,419E-03 0,03657793 ! 3-beta-hydroxy-delta5-steroid dehydrogenase activity GO:0003854 5 5 0,000 5,419E-03 0,03650891 ! monoamine transmembrane transporter activity GO:0008504 5 5 0,000 5,419E-03 0,03644016 ! response to cadmium ion GO:0046686 5 5 0,000 5,419E-03 0,03637166 ! regulation of interleukin-4 production GO:0032673 5 5 0,000 5,419E-03 0,03630342 ! hair follicle maturation GO:0048820 5 5 0,000 5,419E-03 0,03623544 ! regulation of interleukin-10 production GO:0032653 5 5 0,000 5,419E-03 0,03616771 ! ribosomal large subunit biogenesis GO:0042273 5 5 0,000 5,419E-03 0,03610023 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 5,419E-03 0,03603301 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 5,419E-03 0,03596603 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 5,419E-03 0,0358993 GO:0005218|intracellular ligand-gated calcium channel activity, ! general transcriptional repressor activity GO:0016565 5 5 0,000 5,419E-03 0,03583282 ! peroxisome fission GO:0016559 5 5 0,000 5,419E-03 0,03576659 ! alpha-tubulin binding GO:0043014 5 5 0,000 5,419E-03 0,0357006 ! mitotic recombination GO:0006312 5 5 0,000 5,419E-03 0,03563485 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 5,419E-03 0,03556935 ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 5,419E-03 0,03550408 ! positive regulation of chemokine production GO:0032722 5 5 0,000 5,419E-03 0,03543906 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 5,419E-03 0,03537427 ! muscle cell proliferation GO:0033002 5 5 0,000 5,419E-03 0,03530972 ! membrane to membrane docking GO:0022614 5 5 0,000 5,419E-03 0,0352454 ! translation activator activity GO:0008494 5 5 0,000 5,419E-03 0,03518132 ! N-formyl peptide receptor activity GO:0004982 5 5 0,000 5,419E-03 0,03511747 ! coenzyme A biosynthetic process GO:0015937 6 5 0,000 5,419E-03 0,03505385 ! histamine receptor activity GO:0004969 5 5 0,000 5,419E-03 0,03499046 ! dopamine receptor activity GO:0004952 5 5 0,000 5,419E-03 0,0349273 ! galactosidase activity GO:0015925 5 5 0,000 5,419E-03 0,03486437 ! prostaglandin E receptor activity GO:0004957 6 5 0,000 5,419E-03 0,03480166 ! cellular response to nutrient GO:0031670 5 5 0,000 5,419E-03 0,03473918 ! basic amino acid transmembrane transporter activity GO:0015174 5 5 0,000 5,419E-03 0,03467693 ! ATP-gated cation channel activity GO:0004931 7 5 0,000 5,419E-03 0,03461489 ! cytochrome-b5 reductase activity GO:0004128 5 5 0,000 5,419E-03 0,03455308 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 5,419E-03 0,03449149 ! glycine transmembrane transporter activity GO:0015187 5 5 0,000 5,419E-03 0,03443011 ! tyrosine phosphorylation of STAT protein GO:0007260 6 5 0,000 5,419E-03 0,03436896 ! tricarboxylic acid cycle enzyme complex GO:0045239 5 5 0,000 5,419E-03 0,03430802 ! RNA polymerase I transcription factor activity GO:0003701 5 5 0,000 5,419E-03 0,0342473 ! progesterone metabolic process GO:0042448 5 5 0,000 5,419E-03 0,03418679 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 5 5 0,000 5,419E-03 0,0341265 ! disaccharide metabolic process GO:0005984 5 5 0,000 5,419E-03 0,03406642 ! 5'-3' exonuclease activity GO:0008409 5 5 0,000 5,419E-03 0,03400655 ! type II transforming growth factor beta receptor binding GO:0005114 5 5 0,000 5,419E-03 0,03394688 ! histone acetyltransferase binding GO:0035035 5 5 0,000 5,419E-03 0,03388743 ! endosome to lysosome transport GO:0008333 5 5 0,000 5,419E-03 0,03382819 ! glial cell migration GO:0008347 5 5 0,000 5,419E-03 0,03376915 ! S-acyltransferase activity GO:0016417 5 5 0,000 5,419E-03 0,03371032 ! phosphoinositide 3-kinase regulator activity GO:0035014 5 5 0,000 5,419E-03 0,03365169 ! phosphatidylinositol-4-phosphate 3-kinase activity GO:0035005 5 5 0,000 5,419E-03 0,03359327 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 5,419E-03 0,03353505 ! nucleobase transmembrane transporter activity GO:0015205 5 5 0,000 5,419E-03 0,03347703 ! asparaginase activity GO:0004067 5 5 0,000 5,419E-03 0,03341921 ! insemination GO:0007320 5 5 0,000 5,419E-03 0,03336159 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 5,419E-03 0,03330417 ! negative regulation of smooth muscle contraction GO:0045986 6 5 0,000 5,419E-03 0,03324695 ! aminoacylase activity GO:0004046 5 5 0,000 5,419E-03 0,03318992 ! receptor biosynthetic process GO:0032800 5 5 0,000 5,419E-03 0,03313309 ! penetration of zona pellucida GO:0007341 5 5 0,000 5,419E-03 0,03307645 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 6 5 0,000 5,419E-03 0,03302001 ! aldehyde reductase activity GO:0004032 5 5 0,000 5,419E-03 0,03296376 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 5 0,000 5,419E-03 0,03290769 ! unconventional myosin complex GO:0016461 5 5 0,000 5,419E-03 0,03285182 ! carnitine metabolic process GO:0009437 5 5 0,000 5,419E-03 0,03279614 GO:0006577|betaine metabolic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 6 6 0,000 6,499E-03 0,03926879 ! regulation of helicase activity GO:0051095 6 6 0,000 6,499E-03 0,03920246 ! testosterone 17-beta-dehydrogenase activity GO:0050327 6 6 0,000 6,499E-03 0,03913635 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 6 6 0,000 6,499E-03 0,03907046 ! tumor necrosis factor-mediated signaling pathway GO:0033209 6 6 0,000 6,499E-03 0,0390048 ! negative regulation of small GTPase mediated signal transduction GO:0051058 7 6 0,000 6,499E-03 0,03893935 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 7 6 0,000 6,499E-03 0,03887413 ! regulation of hormone biosynthetic process GO:0046885 6 6 0,000 6,499E-03 0,03880912 ! ephrin receptor binding GO:0046875 7 6 0,000 6,499E-03 0,03874433 ! biotin binding GO:0009374 7 6 0,000 6,499E-03 0,03867976 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 6,499E-03 0,0386154 ! insulin receptor substrate binding GO:0043560 7 6 0,000 6,499E-03 0,03855125 ! drug:hydrogen antiporter activity GO:0015307 6 6 0,000 6,499E-03 0,03848732 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 6,499E-03 0,0384236 ! carbohydrate phosphorylation GO:0046835 6 6 0,000 6,499E-03 0,03836009 ! regulation of respiratory gaseous exchange GO:0043576 6 6 0,000 6,499E-03 0,03829679 ! neuron adhesion GO:0007158 6 6 0,000 6,499E-03 0,0382337 ! establishment of tissue polarity GO:0007164 7 6 0,000 6,499E-03 0,03817081 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 6 6 0,000 6,499E-03 0,03810814 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 6,499E-03 0,03804566 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 6 0,000 6,499E-03 0,0379834 ! regulation of cardiac muscle cell proliferation GO:0060043 6 6 0,000 6,499E-03 0,03792133 ! positive regulation of receptor-mediated endocytosis GO:0048260 6 6 0,000 6,499E-03 0,03785947 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 6 6 0,000 6,499E-03 0,03779781 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 6,499E-03 0,03773635 ! eukaryotic translation elongation factor 1 complex GO:0005853 6 6 0,000 6,499E-03 0,03767509 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 6,499E-03 0,03761403 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 6 6 0,000 6,499E-03 0,03755316 ! cytoplasmic microtubule GO:0005881 7 6 0,000 6,499E-03 0,0374925 ! Arp2/3 protein complex GO:0005885 7 6 0,000 6,499E-03 0,03743202 ! neurofilament GO:0005883 6 6 0,000 6,499E-03 0,03737175 ! glial cell fate commitment GO:0021781 6 6 0,000 6,499E-03 0,03731166 ! dynactin complex GO:0005869 6 6 0,000 6,499E-03 0,03725177 ! fibroblast growth factor receptor antagonist activity GO:0030353 6 6 0,000 6,499E-03 0,03719208 GO:0005104|fibroblast growth factor receptor binding, GO:0005152|interleukin-1 receptor antagonist activity, ! translation repressor activity GO:0030371 6 6 0,000 6,499E-03 0,03713257 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 6 6 0,000 6,499E-03 0,03707325 ! lipopolysaccharide binding GO:0001530 6 6 0,000 6,499E-03 0,03701412 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 6,499E-03 0,03695518 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 6,499E-03 0,03689643 ! negative regulation of viral genome replication GO:0045071 6 6 0,000 6,499E-03 0,03683786 ! traversing start control point of mitotic cell cycle GO:0007089 6 6 0,000 6,499E-03 0,03677948 ! protein lipoylation GO:0009249 6 6 0,000 6,499E-03 0,03672129 ! cysteine metabolic process GO:0006534 6 6 0,000 6,499E-03 0,03666328 ! regulation of isotype switching to IgG isotypes GO:0048302 10 6 0,000 6,499E-03 0,03660545 ! histidine catabolic process GO:0006548 6 6 0,000 6,499E-03 0,0365478 GO:0009077|histidine family amino acid catabolic process, ! centromeric heterochromatin GO:0005721 6 6 0,000 6,499E-03 0,03649034 ! mitochondrial respiratory chain complex assembly GO:0033108 6 6 0,000 6,499E-03 0,03643305 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 6 6 0,000 6,499E-03 0,03637595 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 6 6 0,000 6,499E-03 0,03631902 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 6 6 0,000 6,499E-03 0,03626227 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 6 0,000 6,499E-03 0,0362057 ! proline biosynthetic process GO:0006561 7 6 0,000 6,499E-03 0,03614931 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 6,499E-03 0,03609309 ! transforming growth factor beta receptor activity, type I GO:0005025 6 6 0,000 6,499E-03 0,03603704 ! phasic smooth muscle contraction GO:0014821 6 6 0,000 6,499E-03 0,03598117 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 6,499E-03 0,03592547 ! peptidoglycan metabolic process GO:0000270 6 6 0,000 6,499E-03 0,03586995 GO:0009253|peptidoglycan catabolic process, ! cerebral cortex neuron differentiation GO:0021895 6 6 0,000 6,499E-03 0,03581459 ! paraxial mesoderm development GO:0048339 6 6 0,000 6,499E-03 0,03575941 ! melanosome organization GO:0032438 6 6 0,000 6,499E-03 0,03570439 ! mitochondrial outer membrane translocase complex GO:0005742 6 6 0,000 6,499E-03 0,03564955 ! flotillin complex GO:0016600 6 6 0,000 6,499E-03 0,03559487 ! positive regulation of neuroblast proliferation GO:0002052 6 6 0,000 6,499E-03 0,03554036 ! positive regulation of vasoconstriction GO:0045907 6 6 0,000 6,499E-03 0,03548602 ! negative regulation of DNA recombination GO:0045910 6 6 0,000 6,499E-03 0,03543184 ! positive regulation of exocytosis GO:0045921 7 6 0,000 6,499E-03 0,03537783 ! protein tyrosine kinase activator activity GO:0030296 6 6 0,000 6,499E-03 0,03532398 ! positive regulation of fatty acid metabolic process GO:0045923 6 6 0,000 6,499E-03 0,0352703 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 6,499E-03 0,03521678 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of mitotic cell cycle GO:0045931 6 6 0,000 6,499E-03 0,03516342 ! nonhomologous end joining complex GO:0070419 6 6 0,000 6,499E-03 0,03511022 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! DNA damage response, signal transduction resulting in transcription GO:0042772 9 6 0,000 6,499E-03 0,03505718 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! vinculin binding GO:0017166 6 6 0,000 6,499E-03 0,03500431 ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 6,499E-03 0,03495159 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 6,499E-03 0,03489903 ! sodium ion homeostasis GO:0055078 6 6 0,000 6,499E-03 0,03484663 ! protein heterooligomerization GO:0051291 6 6 0,000 6,499E-03 0,03479439 ! negative regulation of gliogenesis GO:0014014 6 6 0,000 6,499E-03 0,0347423 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 8 6 0,000 6,499E-03 0,03469037 ! translation termination factor activity GO:0008079 6 6 0,000 6,499E-03 0,03463859 GO:0003747|translation release factor activity, ! centrosome duplication GO:0051298 6 6 0,000 6,499E-03 0,03458697 ! astrocyte development GO:0014002 6 6 0,000 6,499E-03 0,0345355 ! protein targeting to lysosome GO:0006622 6 6 0,000 6,499E-03 0,03448418 ! purine base biosynthetic process GO:0009113 7 6 0,000 6,499E-03 0,03443302 ! fibrinolysis GO:0042730 7 6 0,000 6,499E-03 0,03438201 ! peptidyl-asparagine modification GO:0018196 6 6 0,000 6,499E-03 0,03433115 GO:0018279|protein amino acid N-linked glycosylation via asparagine, GO:0004579|dolichyl-diphosphooligosaccharide-protein glycotransferase activity, ! eating behavior GO:0042755 6 6 0,000 6,499E-03 0,03428044 ! B cell lineage commitment GO:0002326 6 6 0,000 6,499E-03 0,03422987 ! thiamin and derivative metabolic process GO:0042723 6 6 0,000 6,499E-03 0,03417946 ! response to exogenous dsRNA GO:0043330 6 6 0,000 6,499E-03 0,0341292 ! enucleate erythrocyte differentiation GO:0043353 6 6 0,000 6,499E-03 0,03407908 ! melanosome transport GO:0032402 6 6 0,000 6,499E-03 0,03402911 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 6 6 0,000 6,499E-03 0,03397929 GO:0014066|regulation of phosphoinositide 3-kinase cascade, ! mast cell activation GO:0045576 6 6 0,000 6,499E-03 0,03392961 ! regulation of dopamine secretion GO:0014059 6 6 0,000 6,499E-03 0,03388008 ! regulation of protein kinase B signaling cascade GO:0051896 6 6 0,000 6,499E-03 0,03383069 ! negative regulation of focal adhesion formation GO:0051895 8 6 0,000 6,499E-03 0,03378145 ! nucleoside catabolic process GO:0009164 7 6 0,000 6,499E-03 0,03373235 ! transcription initiation factor activity GO:0016986 6 6 0,000 6,499E-03 0,03368339 ! negative regulation of T cell differentiation GO:0045581 6 6 0,000 6,499E-03 0,03363457 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 6,499E-03 0,0335859 ! Schwann cell development GO:0014044 6 6 0,000 6,499E-03 0,03353736 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 6 0,000 6,499E-03 0,03348897 ! G-protein coupled photoreceptor activity GO:0008020 6 6 0,000 6,499E-03 0,03344071 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 6,499E-03 0,0333926 ! regulation of chondrocyte differentiation GO:0032330 6 6 0,000 6,499E-03 0,03334462 ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 6,499E-03 0,03329678 ! superoxide-generating NADPH oxidase activity GO:0016175 6 6 0,000 6,499E-03 0,03324908 ! nuclear envelope lumen GO:0005641 6 6 0,000 6,499E-03 0,03320151 ! RNA polymerase II transcription elongation factor activity GO:0016944 7 6 0,000 6,499E-03 0,03315408 ! regulation of meiosis GO:0040020 6 6 0,000 6,499E-03 0,03310678 GO:0051445|regulation of meiotic cell cycle, ! establishment of nucleus localization GO:0040023 8 6 0,000 6,499E-03 0,03305962 ! lipoxygenase activity GO:0016165 6 6 0,000 6,499E-03 0,0330126 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 6,499E-03 0,0329657 ! alpha DNA polymerase:primase complex GO:0005658 7 6 0,000 6,499E-03 0,03291894 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 6,499E-03 0,03287232 ! DNA replication factor C complex GO:0005663 6 6 0,000 6,499E-03 0,03282582 ! nuclear origin of replication recognition complex GO:0005664 6 6 0,000 6,499E-03 0,03277946 GO:0000808|origin recognition complex, ! DNA replication factor A complex GO:0005662 6 6 0,000 6,499E-03 0,03273322 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 6,499E-03 0,03268712 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 6,499E-03 0,03264115 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 6,499E-03 0,0325953 ! chromatin silencing complex GO:0005677 6 6 0,000 6,499E-03 0,03254959 GO:0034979|NAD-dependent protein deacetylase activity, GO:0017136|NAD-dependent histone deacetylase activity, ! U12-type spliceosomal complex GO:0005689 7 6 0,000 6,499E-03 0,032504 ! B cell homeostasis GO:0001782 7 6 0,000 6,499E-03 0,03245854 ! regulation of respiratory burst GO:0060263 6 6 0,000 6,499E-03 0,03241321 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 10 6 0,000 6,499E-03 0,032368 GO:0002820|negative regulation of adaptive immune response, ! immunological synapse GO:0001772 6 6 0,000 6,499E-03 0,03232292 ! MutLalpha complex GO:0032389 6 6 0,000 6,499E-03 0,03227796 ! leading edge membrane GO:0031256 6 6 0,000 6,499E-03 0,03223313 ! bis(5'-adenosyl)-triphosphatase activity GO:0047710 6 6 0,000 6,499E-03 0,03218843 ! peptidyl-histidine modification GO:0018202 6 6 0,000 6,499E-03 0,03214384 ! exodeoxyribonuclease activity GO:0004529 6 6 0,000 6,499E-03 0,03209938 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! COPII vesicle coat GO:0030127 6 6 0,000 6,499E-03 0,03205505 GO:0012507|ER to Golgi transport vesicle membrane, ! peptidyl-threonine modification GO:0018210 6 6 0,000 6,499E-03 0,03201083 ! diuresis GO:0030146 6 6 0,000 6,499E-03 0,03196674 GO:0030147|natriuresis, ! definitive hemopoiesis GO:0060216 6 6 0,000 6,499E-03 0,03192277 ! glutathione biosynthetic process GO:0006750 6 6 0,000 6,499E-03 0,03187892 ! HLA-B specific inhibitory MHC class I receptor activity GO:0030109 6 6 0,000 6,499E-03 0,03183519 ! BBSome GO:0034464 6 6 0,000 6,499E-03 0,03179158 ! regulation of keratinocyte differentiation GO:0045616 6 6 0,000 6,499E-03 0,03174809 ! glycerophosphodiester phosphodiesterase activity GO:0008889 6 6 0,000 6,499E-03 0,03170472 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 6,499E-03 0,03166147 ! sodium channel regulator activity GO:0017080 6 6 0,000 6,499E-03 0,03161833 ! glycolipid catabolic process GO:0019377 6 6 0,000 6,499E-03 0,03157531 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 6 6 0,000 6,499E-03 0,03153241 ! nicotinamide nucleotide biosynthetic process GO:0019359 6 6 0,000 6,499E-03 0,03148963 ! porphyrin catabolic process GO:0006787 8 6 0,000 6,499E-03 0,03144696 GO:0033015|tetrapyrrole catabolic process, ! removal of superoxide radicals GO:0019430 6 6 0,000 6,499E-03 0,0314044 ! positive regulation of glucose import GO:0046326 7 6 0,000 6,499E-03 0,03136197 GO:0010828|positive regulation of glucose transport, ! triglyceride catabolic process GO:0019433 6 6 0,000 6,499E-03 0,03131964 ! myeloid cell homeostasis GO:0002262 6 6 0,000 6,499E-03 0,03127743 ! lamin binding GO:0005521 6 6 0,000 6,499E-03 0,03123534 ! ectodermal gut morphogenesis GO:0048567 6 6 0,000 6,499E-03 0,03119335 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 6 6 0,000 6,499E-03 0,03115148 ! pattern recognition receptor signaling pathway GO:0002221 6 6 0,000 6,499E-03 0,03110972 ! negative regulation of calcium ion transport GO:0051926 6 6 0,000 6,499E-03 0,03106808 ! peroxiredoxin activity GO:0051920 6 6 0,000 6,499E-03 0,03102654 ! complement binding GO:0001848 8 6 0,000 6,499E-03 0,03098512 ! catecholamine transport GO:0051937 6 6 0,000 6,499E-03 0,03094381 ! regulation of sensory perception GO:0051931 6 6 0,000 6,499E-03 0,0309026 GO:0051930|regulation of sensory perception of pain, ! muscle adaptation GO:0043500 6 6 0,000 6,499E-03 0,03086151 ! hemopoietic progenitor cell differentiation GO:0002244 6 6 0,000 6,499E-03 0,03082052 ! dipeptidase activity GO:0016805 6 6 0,000 6,499E-03 0,03077965 ! ether hydrolase activity GO:0016803 6 6 0,000 6,499E-03 0,03073888 ! FACIT collagen GO:0005593 6 6 0,000 6,499E-03 0,03069822 ! actin filament polymerization GO:0030041 8 6 0,000 6,499E-03 0,03065767 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 6,499E-03 0,03061722 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 6 6 0,000 6,499E-03 0,03057688 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 6 0,000 6,499E-03 0,03053665 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 6,499E-03 0,03049652 ! negative regulation of synaptic transmission GO:0050805 7 6 0,000 6,499E-03 0,0304565 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 6,499E-03 0,03041659 ! organ regeneration GO:0031100 6 6 0,000 6,499E-03 0,03037677 ! Golgi transport complex GO:0017119 6 6 0,000 6,499E-03 0,03033707 ! sheet-forming collagen GO:0030935 6 6 0,000 6,499E-03 0,03029746 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 6,499E-03 0,03025796 ! positive regulation of coagulation GO:0050820 7 6 0,000 6,499E-03 0,03021856 ! defense response to Gram-negative bacterium GO:0050829 6 6 0,000 6,499E-03 0,03017927 ! positive regulation of MHC class II biosynthetic process GO:0045348 6 6 0,000 6,499E-03 0,03014007 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 6 6 0,000 6,499E-03 0,03010098 ! thioredoxin-disulfide reductase activity GO:0004791 6 6 0,000 6,499E-03 0,03006199 ! sphingomyelin phosphodiesterase activity GO:0004767 7 6 0,000 6,499E-03 0,0300231 ! regulation of cGMP metabolic process GO:0030823 6 6 0,000 6,499E-03 0,02998431 ! myoblast cell fate commitment GO:0048625 6 6 0,000 6,499E-03 0,02994562 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 6,499E-03 0,02990703 ! DNA synthesis during DNA repair GO:0000731 7 6 0,000 6,499E-03 0,02986854 ! neutral lipid biosynthetic process GO:0046460 6 6 0,000 6,499E-03 0,02983015 GO:0046463|acylglycerol biosynthetic process, ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 6 6 0,000 6,499E-03 0,02979185 ! nuclear telomere cap complex GO:0000783 6 6 0,000 6,499E-03 0,02975366 GO:0000782|telomere cap complex, ! Golgi to endosome transport GO:0006895 6 6 0,000 6,499E-03 0,02971556 ! negative regulation of JAK-STAT cascade GO:0046426 7 6 0,000 6,499E-03 0,02967756 ! sterol carrier activity GO:0005498 6 6 0,000 6,499E-03 0,02963966 ! positive regulation of cell-cell adhesion GO:0022409 6 6 0,000 6,499E-03 0,02960186 ! succinate metabolic process GO:0006105 6 6 0,000 6,499E-03 0,02956415 ! myelin sheath GO:0043209 6 6 0,000 6,499E-03 0,02952653 ! perikaryon GO:0043204 7 6 0,000 6,499E-03 0,02948902 ! oxaloacetate metabolic process GO:0006107 7 6 0,000 6,499E-03 0,02945159 ! malate metabolic process GO:0006108 6 6 0,000 6,499E-03 0,02941426 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 6 6 0,000 6,499E-03 0,02937703 ! posttranscriptional gene silencing by RNA GO:0035194 6 6 0,000 6,499E-03 0,02933989 GO:0016441|posttranscriptional gene silencing, ! mating behavior GO:0007617 6 6 0,000 6,499E-03 0,02930285 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 6,499E-03 0,0292659 ! rhythmic behavior GO:0007622 7 6 0,000 6,499E-03 0,02922904 ! copulation GO:0007620 6 6 0,000 6,499E-03 0,02919227 ! erythrocyte maturation GO:0043249 6 6 0,000 6,499E-03 0,0291556 ! equilibrioception GO:0050957 6 6 0,000 6,499E-03 0,02911901 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 6,499E-03 0,02908252 ! G-protein coupled receptor kinase activity GO:0004703 6 6 0,000 6,499E-03 0,02904613 ! chemosensory behavior GO:0007635 6 6 0,000 6,499E-03 0,02900982 ! synaptic transmission, dopaminergic GO:0001963 7 6 0,000 6,499E-03 0,0289736 ! mechanosensory behavior GO:0007638 6 6 0,000 6,499E-03 0,02893747 ! response to interferon-gamma GO:0034341 6 6 0,000 6,499E-03 0,02890144 ! spinal cord patterning GO:0021511 6 6 0,000 6,499E-03 0,02886549 ! cGMP-mediated signaling GO:0019934 6 6 0,000 6,499E-03 0,02882963 ! protein geranylgeranyltransferase activity GO:0004661 6 6 0,000 6,499E-03 0,02879386 ! activation of MAPKKK activity GO:0000185 6 6 0,000 6,499E-03 0,02875818 ! nerve growth factor receptor signaling pathway GO:0048011 8 6 0,000 6,499E-03 0,02872259 ! glucosyltransferase activity GO:0046527 6 6 0,000 6,499E-03 0,02868709 ! sphingoid catabolic process GO:0046521 6 6 0,000 6,499E-03 0,02865167 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 6,499E-03 0,02861634 ! activin receptor activity GO:0017002 6 6 0,000 6,499E-03 0,0285811 ! ovulation GO:0030728 6 6 0,000 6,499E-03 0,02854595 ! dopamine binding GO:0035240 7 6 0,000 6,499E-03 0,02851088 ! hyperosmotic response GO:0006972 6 6 0,000 6,499E-03 0,0284759 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 6 6 0,000 6,499E-03 0,028441 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 6 0,000 6,499E-03 0,02840619 ! nuclear localization sequence binding GO:0008139 6 6 0,000 6,499E-03 0,02837146 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 6,499E-03 0,02833682 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 6,499E-03 0,02830226 ! copper ion transmembrane transporter activity GO:0005375 6 6 0,000 6,499E-03 0,02826779 ! poly(A) RNA binding GO:0008143 6 6 0,000 6,499E-03 0,0282334 ! positive transcription elongation factor activity GO:0008159 6 6 0,000 6,499E-03 0,02819909 ! regulation of glycogen metabolic process GO:0070873 7 6 0,000 6,499E-03 0,02816487 GO:0032881|regulation of polysaccharide metabolic process, ! maintenance of protein location in nucleus GO:0051457 6 6 0,000 6,499E-03 0,02813073 ! intracellular pH reduction GO:0051452 6 6 0,000 6,499E-03 0,02809668 GO:0045851|pH reduction, ! purine salvage GO:0043101 8 6 0,000 6,499E-03 0,0280627 ! nucleotide-sugar transmembrane transporter activity GO:0005338 6 6 0,000 6,499E-03 0,02802881 ! neurotrophin binding GO:0043121 6 6 0,000 6,499E-03 0,027995 ! ciliary rootlet GO:0035253 6 6 0,000 6,499E-03 0,02796127 ! neurotransmitter catabolic process GO:0042135 10 6 0,000 6,499E-03 0,02792762 ! ruffle organization GO:0031529 6 6 0,000 6,499E-03 0,02789406 ! T cell mediated immunity GO:0002456 6 6 0,000 6,499E-03 0,02786057 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 7 6 0,000 6,499E-03 0,02782716 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! carnitine transport GO:0015879 6 6 0,000 6,499E-03 0,02779384 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 6,499E-03 0,02776059 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! palmitoyl-CoA hydrolase activity GO:0016290 6 6 0,000 6,499E-03 0,02772743 ! S-methyltransferase activity GO:0008172 6 6 0,000 6,499E-03 0,02769434 ! phospholipase D activity GO:0004630 6 6 0,000 6,499E-03 0,02766133 ! rRNA modification GO:0000154 6 6 0,000 6,499E-03 0,0276284 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 6,499E-03 0,02759555 ! neuronal ion channel clustering GO:0045161 6 6 0,000 6,499E-03 0,02756277 ! response to UV-B GO:0010224 6 6 0,000 6,499E-03 0,02753008 ! interaction with symbiont GO:0051702 6 6 0,000 6,499E-03 0,02749746 ! negative regulation of insulin receptor signaling pathway GO:0046627 6 6 0,000 6,499E-03 0,02746492 ! IgG binding GO:0019864 6 6 0,000 6,499E-03 0,02743245 ! positive regulation of cytokine production during immune response GO:0002720 6 6 0,000 6,499E-03 0,02740006 ! base-excision repair, AP site formation GO:0006285 6 6 0,000 6,499E-03 0,02736775 ! benzodiazepine receptor activity GO:0008503 6 6 0,000 6,499E-03 0,02733552 ! response to copper ion GO:0046688 6 6 0,000 6,499E-03 0,02730336 ! DNA topological change GO:0006265 6 6 0,000 6,499E-03 0,02727127 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 6,499E-03 0,02723927 ! dendrite morphogenesis GO:0048813 6 6 0,000 6,499E-03 0,02720733 ! regulation of interleukin-1 beta production GO:0032651 6 6 0,000 6,499E-03 0,02717547 ! regulation of myeloid cell apoptosis GO:0033032 6 6 0,000 6,499E-03 0,02714369 ! positive regulation of tumor necrosis factor production GO:0032760 6 6 0,000 6,499E-03 0,02711198 ! nucleosome disassembly GO:0006337 6 6 0,000 6,499E-03 0,02708034 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! inositol trisphosphate 3-kinase activity GO:0008440 6 6 0,000 6,499E-03 0,02704878 ! regulation of mast cell activation GO:0033003 6 6 0,000 6,499E-03 0,02701729 ! guanylyltransferase activity GO:0070568 6 6 0,000 6,499E-03 0,02698588 ! receptor internalization GO:0031623 7 6 0,000 6,499E-03 0,02695454 ! neuropeptide Y receptor activity GO:0004983 6 6 0,000 6,499E-03 0,02692327 ! ATP-dependent peptidase activity GO:0004176 6 6 0,000 6,499E-03 0,02689207 ! serine-type carboxypeptidase activity GO:0004185 6 6 0,000 6,499E-03 0,02686094 GO:0070008|serine-type exopeptidase activity, ! protein deubiquitination GO:0016579 6 6 0,000 6,499E-03 0,02682989 ! negative regulation of neuroblast proliferation GO:0007406 6 6 0,000 6,499E-03 0,02679891 ! NuRD complex GO:0016581 6 6 0,000 6,499E-03 0,026768 ! nucleosome positioning GO:0016584 6 6 0,000 6,499E-03 0,02673716 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 6,499E-03 0,02670639 ! alpha-adrenergic receptor activity GO:0004936 8 6 0,000 6,499E-03 0,0266757 ! glycine binding GO:0016594 8 6 0,000 6,499E-03 0,02664507 ! costamere GO:0043034 7 6 0,000 6,499E-03 0,02661451 ! A band GO:0031672 6 6 0,000 6,499E-03 0,02658403 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 6,499E-03 0,02655361 ! dopamine biosynthetic process GO:0042416 7 6 0,000 6,499E-03 0,02652326 ! procollagen-proline dioxygenase activity GO:0019798 6 6 0,000 6,499E-03 0,02649298 ! negative regulation of axon extension GO:0030517 6 6 0,000 6,499E-03 0,02646278 ! actin monomer binding GO:0003785 6 6 0,000 6,499E-03 0,02643264 ! lysozyme activity GO:0003796 6 6 0,000 6,499E-03 0,02640257 ! regulation of Rac protein signal transduction GO:0035020 6 6 0,000 6,499E-03 0,02637256 ! ATP catabolic process GO:0006200 6 6 0,000 6,499E-03 0,02634263 ! determination of adult lifespan GO:0008340 6 6 0,000 6,499E-03 0,02631276 ! somatic stem cell maintenance GO:0035019 6 6 0,000 6,499E-03 0,02628296 ! negative regulation of organic acid transport GO:0032891 6 6 0,000 6,499E-03 0,02625323 ! establishment of apical/basal cell polarity GO:0035089 6 6 0,000 6,499E-03 0,02622356 ! calcium-dependent phospholipase A2 activity GO:0047498 6 6 0,000 6,499E-03 0,02619397 ! O-acetyltransferase activity GO:0016413 6 6 0,000 6,499E-03 0,02616444 ! CoA-ligase activity GO:0016405 6 6 0,000 6,499E-03 0,02613497 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 6,499E-03 0,02610557 ! IkappaB kinase complex GO:0008385 6 6 0,000 6,499E-03 0,02607624 ! pyrimidine nucleotide catabolic process GO:0006244 6 6 0,000 6,499E-03 0,02604698 ! store-operated calcium channel activity GO:0015279 6 6 0,000 6,499E-03 0,02601777 ! aminomethyltransferase activity GO:0004047 6 6 0,000 6,499E-03 0,02598864 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 6 6 0,000 6,499E-03 0,02595957 ! alkaline phosphatase activity GO:0004035 6 6 0,000 6,499E-03 0,02593056 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 6 6 0,000 6,499E-03 0,02590162 ! oligosaccharide biosynthetic process GO:0009312 7 7 0,000 7,578E-03 0,03016952 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 7,578E-03 0,03013592 ! sleep GO:0030431 7 7 0,000 7,578E-03 0,0301024 ! synaptonemal complex assembly GO:0007130 7 7 0,000 7,578E-03 0,03006895 GO:0070193|synaptonemal complex organization, ! forebrain regionalization GO:0021871 7 7 0,000 7,578E-03 0,03003558 ! cell proliferation in forebrain GO:0021846 7 7 0,000 7,578E-03 0,03000228 ! proteasome regulatory particle GO:0005838 8 7 0,000 7,578E-03 0,02996905 ! meiotic prophase I GO:0007128 7 7 0,000 7,578E-03 0,0299359 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 7 0,000 7,578E-03 0,02990282 ! SMAD protein nuclear translocation GO:0007184 8 7 0,000 7,578E-03 0,02986982 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 7 7 0,000 7,578E-03 0,02983689 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 7,578E-03 0,02980403 ! actin-myosin filament sliding GO:0033275 7 7 0,000 7,578E-03 0,02977124 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! signal peptide processing GO:0006465 7 7 0,000 7,578E-03 0,02973852 ! glycine hydroxymethyltransferase activity GO:0004372 8 7 0,000 7,578E-03 0,02970588 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 7,578E-03 0,02967331 ! macrophage chemotaxis GO:0048246 7 7 0,000 7,578E-03 0,02964081 ! cerebral cortex cell migration GO:0021795 7 7 0,000 7,578E-03 0,02960838 ! tachykinin receptor signaling pathway GO:0007217 7 7 0,000 7,578E-03 0,02957602 ! membrane hyperpolarization GO:0060081 7 7 0,000 7,578E-03 0,02954373 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 7,578E-03 0,02951151 ! enoyl-CoA hydratase activity GO:0004300 7 7 0,000 7,578E-03 0,02947936 ! DNA replication origin binding GO:0003688 7 7 0,000 7,578E-03 0,02944729 ! ATPase binding GO:0051117 7 7 0,000 7,578E-03 0,02941528 ! positive regulation of glycolysis GO:0045821 7 7 0,000 7,578E-03 0,02938334 ! positive regulation of isotype switching GO:0045830 11 7 0,000 7,578E-03 0,02935147 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 8 7 0,000 7,578E-03 0,02931967 ! ribonucleoside triphosphate catabolic process GO:0009203 7 7 0,000 7,578E-03 0,02928794 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! protein-cofactor linkage GO:0018065 7 7 0,000 7,578E-03 0,02925628 ! positive regulation of chemokine biosynthetic process GO:0045080 7 7 0,000 7,578E-03 0,02922468 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 7 7 0,000 7,578E-03 0,02919316 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! thymic T cell selection GO:0045061 11 7 0,000 7,578E-03 0,0291617 ! structural constituent of tooth enamel GO:0030345 7 7 0,000 7,578E-03 0,02913031 ! transepithelial chloride transport GO:0030321 7 7 0,000 7,578E-03 0,02909898 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 7,578E-03 0,02906773 ! glycine catabolic process GO:0006546 7 7 0,000 7,578E-03 0,02903654 GO:0009071|serine family amino acid catabolic process, ! deoxyribonucleotide biosynthetic process GO:0009263 8 7 0,000 7,578E-03 0,02900542 ! cytoskeletal anchoring at plasma membrane GO:0007016 8 7 0,000 7,578E-03 0,02897436 ! response to pH GO:0009268 7 7 0,000 7,578E-03 0,02894338 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 7,578E-03 0,02891245 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! polyamine biosynthetic process GO:0006596 7 7 0,000 7,578E-03 0,0288816 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 7 7 0,000 7,578E-03 0,02885081 ! endosome organization GO:0007032 7 7 0,000 7,578E-03 0,02882008 ! thyroid hormone generation GO:0006590 7 7 0,000 7,578E-03 0,02878942 ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 7,578E-03 0,02875883 GO:0021940|positive regulation of granule cell precursor proliferation, ! reverse cholesterol transport GO:0043691 7 7 0,000 7,578E-03 0,0287283 ! tumor necrosis factor receptor activity GO:0005031 7 7 0,000 7,578E-03 0,02869783 ! indolalkylamine metabolic process GO:0006586 7 7 0,000 7,578E-03 0,02866743 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! proton-transporting V-type ATPase, V1 domain GO:0033180 7 7 0,000 7,578E-03 0,0286371 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 7,578E-03 0,02860682 ! retinoid X receptor binding GO:0046965 7 7 0,000 7,578E-03 0,02857662 ! central nervous system neuron axonogenesis GO:0021955 7 7 0,000 7,578E-03 0,02854647 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 7,578E-03 0,02851639 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! platelet-derived growth factor receptor activity GO:0005017 7 7 0,000 7,578E-03 0,02848637 ! urea metabolic process GO:0019627 7 7 0,000 7,578E-03 0,02845642 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! retinoic acid receptor signaling pathway GO:0048384 7 7 0,000 7,578E-03 0,02842653 ! regulation of type I interferon production GO:0032479 8 7 0,000 7,578E-03 0,0283967 ! peroxisomal matrix GO:0005782 7 7 0,000 7,578E-03 0,02836693 GO:0031907|microbody lumen, ! methyltransferase complex GO:0034708 7 7 0,000 7,578E-03 0,02833723 GO:0035097|histone methyltransferase complex, ! response to dietary excess GO:0002021 7 7 0,000 7,578E-03 0,02830759 ! p53 binding GO:0002039 7 7 0,000 7,578E-03 0,02827801 ! osteoblast development GO:0002076 8 7 0,000 7,578E-03 0,02824849 ! positive regulation of nitric-oxide synthase activity GO:0051000 7 7 0,000 7,578E-03 0,02821904 ! lipid phosphatase activity GO:0042577 7 7 0,000 7,578E-03 0,02818964 ! male sex determination GO:0030238 7 7 0,000 7,578E-03 0,02816031 ! clathrin binding GO:0030276 8 7 0,000 7,578E-03 0,02813104 ! negative regulation of translational initiation GO:0045947 7 7 0,000 7,578E-03 0,02810182 ! determination of anterior/posterior axis, embryo GO:0008595 7 7 0,000 7,578E-03 0,02807267 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 7 7 0,000 7,578E-03 0,02804358 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 7,578E-03 0,02801455 GO:0030204|chondroitin sulfate metabolic process, ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 7,578E-03 0,02798558 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 7,578E-03 0,02795667 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 7,578E-03 0,02792782 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 7,578E-03 0,02789903 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 8 7 0,000 7,578E-03 0,02787029 ! hyaluronan metabolic process GO:0030212 8 7 0,000 7,578E-03 0,02784162 ! protein retention in ER lumen GO:0006621 7 7 0,000 7,578E-03 0,02781301 ! cardiac muscle cell differentiation GO:0055007 7 7 0,000 7,578E-03 0,02778445 ! peptidyl-arginine modification GO:0018195 7 7 0,000 7,578E-03 0,02775595 ! regulation of circadian rhythm GO:0042752 7 7 0,000 7,578E-03 0,02772752 ! Hsp90 protein binding GO:0051879 7 7 0,000 7,578E-03 0,02769914 ! MutSalpha complex binding GO:0032407 8 7 0,000 7,578E-03 0,02767081 ! regulation of fat cell differentiation GO:0045598 7 7 0,000 7,578E-03 0,02764255 ! establishment of melanosome localization GO:0032401 7 7 0,000 7,578E-03 0,02761434 ! gas homeostasis GO:0033483 7 7 0,000 7,578E-03 0,02758619 ! cranial nerve morphogenesis GO:0021602 7 7 0,000 7,578E-03 0,0275581 ! subpallium development GO:0021544 7 7 0,000 7,578E-03 0,02753007 ! laminin-1 complex GO:0005606 7 7 0,000 7,578E-03 0,02750209 GO:0043256|laminin complex, ! molybdopterin cofactor biosynthetic process GO:0032324 7 7 0,000 7,578E-03 0,02747417 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 8 7 0,000 7,578E-03 0,0274463 ! eye photoreceptor cell differentiation GO:0001754 10 7 0,000 7,578E-03 0,0274185 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 7 7 0,000 7,578E-03 0,02739074 ! positive regulation of immunoglobulin mediated immune response GO:0002891 11 7 0,000 7,578E-03 0,02736305 GO:0002714|positive regulation of B cell mediated immunity, ! protein sumoylation GO:0016925 7 7 0,000 7,578E-03 0,02733541 ! establishment of chromosome localization GO:0051303 7 7 0,000 7,578E-03 0,02730783 GO:0050000|chromosome localization, ! regulation of lipid transport GO:0032368 7 7 0,000 7,578E-03 0,0272803 ! regulation of cell division GO:0051302 7 7 0,000 7,578E-03 0,02725283 ! chromatin assembly complex GO:0005678 7 7 0,000 7,578E-03 0,02722541 ! sex chromatin GO:0001739 7 7 0,000 7,578E-03 0,02719805 GO:0000803|sex chromosome, ! oligosaccharyl transferase activity GO:0004576 7 7 0,000 7,578E-03 0,02717074 ! chitinase activity GO:0004568 7 7 0,000 7,578E-03 0,02714349 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 7 7 0,000 7,578E-03 0,02711629 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 7 7 0,000 7,578E-03 0,02708915 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 10 7 0,000 7,578E-03 0,02706206 ! inhibitory MHC class I receptor activity GO:0032396 7 7 0,000 7,578E-03 0,02703502 GO:0030110|HLA-C specific inhibitory MHC class I receptor activity, ! ER to Golgi transport vesicle GO:0030134 7 7 0,000 7,578E-03 0,02700804 ! molybdenum ion binding GO:0030151 7 7 0,000 7,578E-03 0,02698111 ! centriolar satellite GO:0034451 8 7 0,000 7,578E-03 0,02695424 ! positive regulation of epidermis development GO:0045684 7 7 0,000 7,578E-03 0,02692742 ! proteasome regulator activity GO:0010860 7 7 0,000 7,578E-03 0,02690065 ! antibiotic transport GO:0042891 7 7 0,000 7,578E-03 0,02687394 ! negative regulation of transmission of nerve impulse GO:0051970 8 7 0,000 7,578E-03 0,02684728 ! regulation of synaptic transmission, glutamatergic GO:0051966 7 7 0,000 7,578E-03 0,02682067 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 7,578E-03 0,02679411 ! aspartate family amino acid catabolic process GO:0009068 7 7 0,000 7,578E-03 0,02676761 ! Wnt receptor activity GO:0042813 7 7 0,000 7,578E-03 0,02674116 ! regulation of protein homodimerization activity GO:0043496 7 7 0,000 7,578E-03 0,02671476 ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 7 7 0,000 7,578E-03 0,02668842 ! positive regulation of viral reproduction GO:0048524 7 7 0,000 7,578E-03 0,02666212 ! negative regulation of viral reproduction GO:0048525 7 7 0,000 7,578E-03 0,02663588 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 9 7 0,000 7,578E-03 0,02660969 ! blastocyst growth GO:0001832 7 7 0,000 7,578E-03 0,02658355 ! pigment granule transport GO:0051904 7 7 0,000 7,578E-03 0,02655746 ! lymphocyte activation during immune response GO:0002285 7 7 0,000 7,578E-03 0,02653143 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 7,578E-03 0,02650544 ! negative regulation of fibrinolysis GO:0051918 7 7 0,000 7,578E-03 0,02647951 ! negative regulation of telomere maintenance GO:0032205 7 7 0,000 7,578E-03 0,02645362 ! cerebellar cortex formation GO:0021697 8 7 0,000 7,578E-03 0,02642779 ! activation of innate immune response GO:0002218 7 7 0,000 7,578E-03 0,02640201 GO:0002758|innate immune response-activating signal transduction, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 7 7 0,000 7,578E-03 0,02637627 ! natural killer cell mediated immunity GO:0002228 7 7 0,000 7,578E-03 0,02635059 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of synaptic transmission, dopaminergic GO:0032225 7 7 0,000 7,578E-03 0,02632496 ! regulation of synaptic transmission, GABAergic GO:0032228 7 7 0,000 7,578E-03 0,02629937 ! flavin-containing monooxygenase activity GO:0004499 7 7 0,000 7,578E-03 0,02627384 ! regulation of muscle adaptation GO:0043502 7 7 0,000 7,578E-03 0,02624836 ! sequestering of metal ion GO:0051238 7 7 0,000 7,578E-03 0,02622292 ! regulation of T cell receptor signaling pathway GO:0050856 8 7 0,000 7,578E-03 0,02619754 ! membrane attack complex GO:0005579 7 7 0,000 7,578E-03 0,0261722 ! fibrinogen complex GO:0005577 7 7 0,000 7,578E-03 0,02614691 ! septin complex GO:0031105 9 7 0,000 7,578E-03 0,02612168 GO:0032156|septin cytoskeleton, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 7 7 0,000 7,578E-03 0,02609649 ! positive regulation of microtubule polymerization GO:0031116 7 7 0,000 7,578E-03 0,02607134 ! cellular anion homeostasis GO:0030002 7 7 0,000 7,578E-03 0,02604625 GO:0055081|anion homeostasis, ! positive regulation of cyclic nucleotide metabolic process GO:0030801 7 7 0,000 7,578E-03 0,02602121 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! behavioral response to cocaine GO:0048148 9 7 0,000 7,578E-03 0,02599621 ! autophagic vacuole formation GO:0000045 8 7 0,000 7,578E-03 0,02597126 ! negative regulation of smooth muscle cell proliferation GO:0048662 7 7 0,000 7,578E-03 0,02594636 ! translation initiation factor binding GO:0031369 7 7 0,000 7,578E-03 0,02592151 ! regulation of lipid catabolic process GO:0050994 7 7 0,000 7,578E-03 0,0258967 ! activin binding GO:0048185 7 7 0,000 7,578E-03 0,02587195 ! syncytium formation by plasma membrane fusion GO:0000768 7 7 0,000 7,578E-03 0,02584724 GO:0007520|myoblast fusion, ! nucleotide-excision repair, DNA incision GO:0033683 7 7 0,000 7,578E-03 0,02582257 ! oligosaccharyltransferase complex GO:0008250 7 7 0,000 7,578E-03 0,02579796 ! phototransduction, visible light GO:0007603 7 7 0,000 7,578E-03 0,02577339 ! positive regulation of neurotransmitter transport GO:0051590 7 7 0,000 7,578E-03 0,02574886 ! lipoprotein transport GO:0042953 7 7 0,000 7,578E-03 0,02572439 ! cell division site part GO:0032155 7 7 0,000 7,578E-03 0,02569996 GO:0032153|cell division site, ! laminin binding GO:0043236 9 7 0,000 7,578E-03 0,02567557 ! detection of mechanical stimulus involved in sensory perception GO:0050974 7 7 0,000 7,578E-03 0,02565124 ! phospholipid efflux GO:0033700 7 7 0,000 7,578E-03 0,02562695 ! DNA insertion or deletion binding GO:0032135 7 7 0,000 7,578E-03 0,0256027 GO:0032138|single base insertion or deletion binding, ! glucocorticoid metabolic process GO:0008211 7 7 0,000 7,578E-03 0,0255785 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 7 7 0,000 7,578E-03 0,02555435 ! poly-purine tract binding GO:0070717 7 7 0,000 7,578E-03 0,02553024 ! T-helper 1 type immune response GO:0042088 7 7 0,000 7,578E-03 0,02550618 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 7,578E-03 0,02548216 GO:0032107|regulation of response to nutrient levels, ! amyloid precursor protein catabolic process GO:0042987 7 7 0,000 7,578E-03 0,02545819 ! leukocyte degranulation GO:0043299 7 7 0,000 7,578E-03 0,02543426 ! sodium:phosphate symporter activity GO:0005436 7 7 0,000 7,578E-03 0,02541038 ! bile acid and bile salt transport GO:0015721 7 7 0,000 7,578E-03 0,02538654 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 7,578E-03 0,02536275 ! glycerol ether biosynthetic process GO:0046504 7 7 0,000 7,578E-03 0,025339 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 7,578E-03 0,0253153 GO:0046513|ceramide biosynthetic process, ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 7,578E-03 0,02529164 ! pigment granule organization GO:0048753 7 7 0,000 7,578E-03 0,02526803 ! eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 7 7 0,000 7,578E-03 0,02524446 ! regulation of interleukin-8 biosynthetic process GO:0045414 8 7 0,000 7,578E-03 0,02522093 ! regulation of pigmentation during development GO:0048070 10 7 0,000 7,578E-03 0,02519745 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 7 7 0,000 7,578E-03 0,02517401 ! macrophage activation GO:0042116 7 7 0,000 7,578E-03 0,02515061 ! positive regulation of activated T cell proliferation GO:0042104 7 7 0,000 7,578E-03 0,02512726 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 7 7 0,000 7,578E-03 0,02510395 ! galactose metabolic process GO:0006012 7 7 0,000 7,578E-03 0,02508068 ! vesicle fusion GO:0006906 7 7 0,000 7,578E-03 0,02505746 ! positive regulation of insulin secretion GO:0032024 7 7 0,000 7,578E-03 0,02503428 ! glycerol ether catabolic process GO:0044269 7 7 0,000 7,578E-03 0,02501114 GO:0046464|acylglycerol catabolic process, ! virus-infected cell apoptosis GO:0006926 7 7 0,000 7,578E-03 0,02498805 ! NuA4 histone acetyltransferase complex GO:0035267 8 7 0,000 7,578E-03 0,024965 ! nucleoside transmembrane transporter activity GO:0005337 7 7 0,000 7,578E-03 0,02494199 GO:0015858|nucleoside transport, ! regulation of vascular permeability GO:0043114 7 7 0,000 7,578E-03 0,02491902 ! regulation of multicellular organismal metabolic process GO:0044246 8 7 0,000 7,578E-03 0,0248961 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 7,578E-03 0,02487321 ! peptidyl-proline dioxygenase activity GO:0031543 7 7 0,000 7,578E-03 0,02485037 ! inclusion body GO:0016234 7 7 0,000 7,578E-03 0,02482757 ! parturition GO:0007567 7 7 0,000 7,578E-03 0,02480482 ! tRNA methyltransferase activity GO:0008175 7 7 0,000 7,578E-03 0,0247821 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 7 7 0,000 7,578E-03 0,02475943 ! intercalated disc GO:0014704 8 7 0,000 7,578E-03 0,0247368 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 7,578E-03 0,02471421 ! neural nucleus development GO:0048857 7 7 0,000 7,578E-03 0,02469166 ! intermediate filament organization GO:0045109 8 7 0,000 7,578E-03 0,02466915 ! skeletal muscle contraction GO:0003009 7 7 0,000 7,578E-03 0,02464668 ! response to antibiotic GO:0046677 7 7 0,000 7,578E-03 0,02462425 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 7 7 0,000 7,578E-03 0,02460187 ! preribosome GO:0030684 7 7 0,000 7,578E-03 0,02457952 ! positive regulation of production of molecular mediator of immune response GO:0002702 7 7 0,000 7,578E-03 0,02455722 ! hydrogen-exporting ATPase activity, phosphorylative mechanism GO:0008553 7 7 0,000 7,578E-03 0,02453496 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 7 7 0,000 7,578E-03 0,02451273 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 7,578E-03 0,02449055 ! regulation of interleukin-1 production GO:0032652 7 7 0,000 7,578E-03 0,02446841 ! phosphofructokinase activity GO:0008443 7 7 0,000 7,578E-03 0,0244463 ! postreplication repair GO:0006301 7 7 0,000 7,578E-03 0,02442424 ! gap junction channel activity GO:0005243 7 7 0,000 7,578E-03 0,02440221 ! transcription from RNA polymerase I promoter GO:0006360 7 7 0,000 7,578E-03 0,02438023 ! mitochondrion morphogenesis GO:0070584 8 7 0,000 7,578E-03 0,02435829 ! transcription termination GO:0006353 8 7 0,000 7,578E-03 0,02433638 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 7 7 0,000 7,578E-03 0,02431452 ! tetracycline transporter activity GO:0008493 7 7 0,000 7,578E-03 0,02429269 GO:0042895|antibiotic transporter activity, ! cytidylyltransferase activity GO:0070567 7 7 0,000 7,578E-03 0,0242709 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 7,578E-03 0,02424915 ! melanocortin receptor activity GO:0004977 7 7 0,000 7,578E-03 0,02422744 ! coenzyme A metabolic process GO:0015936 8 7 0,000 7,578E-03 0,02420577 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 7 0,000 7,578E-03 0,02418414 ! regulation of macrophage activation GO:0043030 7 7 0,000 7,578E-03 0,02416255 ! cytidine deaminase activity GO:0004126 7 7 0,000 7,578E-03 0,024141 ! inositol trisphosphate kinase activity GO:0051766 7 7 0,000 7,578E-03 0,02411948 ! apical protein localization GO:0045176 7 7 0,000 7,578E-03 0,024098 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 7,578E-03 0,02407656 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 7,578E-03 0,02405516 ! virion binding GO:0046790 10 7 0,000 7,578E-03 0,0240338 ! nonprotein amino acid metabolic process GO:0019794 7 7 0,000 7,578E-03 0,02401247 ! protein prenyltransferase activity GO:0008318 7 7 0,000 7,578E-03 0,02399118 ! protein modification by small protein removal GO:0070646 7 7 0,000 7,578E-03 0,02396993 ! adult feeding behavior GO:0008343 7 7 0,000 7,578E-03 0,02394872 ! CoA carboxylase activity GO:0016421 7 7 0,000 7,578E-03 0,02392755 ! microtubule basal body GO:0005932 7 7 0,000 7,578E-03 0,02390641 ! positive regulation of NF-kappaB import into nucleus GO:0042346 7 7 0,000 7,578E-03 0,02388531 ! embryonic heart tube development GO:0035050 7 7 0,000 7,578E-03 0,02386425 ! kainate selective glutamate receptor activity GO:0015277 7 7 0,000 7,578E-03 0,02384322 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 7,578E-03 0,02382223 ! positive regulation of smooth muscle contraction GO:0045987 7 7 0,000 7,578E-03 0,02380128 ! rRNA transcription GO:0009303 8 8 0,000 8,656E-03 0,02716374 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 8 8 0,000 8,656E-03 0,02713989 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 8,656E-03 0,02711608 ! sodium:hydrogen antiporter activity GO:0015385 8 8 0,000 8,656E-03 0,02709232 GO:0005451|monovalent cation:hydrogen antiporter activity, ! negative regulation of lipid biosynthetic process GO:0051055 9 8 0,000 8,656E-03 0,02706859 ! cation:chloride symporter activity GO:0015377 9 8 0,000 8,656E-03 0,02704491 ! positive regulation of small GTPase mediated signal transduction GO:0051057 8 8 0,000 8,656E-03 0,02702127 GO:0046579|positive regulation of Ras protein signal transduction, ! forebrain neuron differentiation GO:0021879 9 8 0,000 8,656E-03 0,02699767 ! male meiosis GO:0007140 8 8 0,000 8,656E-03 0,02697411 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 8 8 0,000 8,656E-03 0,02695059 ! N-glycan processing GO:0006491 8 8 0,000 8,656E-03 0,02692712 ! regulation of smooth muscle cell migration GO:0014910 9 8 0,000 8,656E-03 0,02690368 ! protein self-association GO:0043621 8 8 0,000 8,656E-03 0,02688029 ! RNA methylation GO:0001510 8 8 0,000 8,656E-03 0,02685693 ! prostaglandin biosynthetic process GO:0001516 9 8 0,000 8,656E-03 0,02683362 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 8 8 0,000 8,656E-03 0,02681035 ! regulation of activated T cell proliferation GO:0046006 8 8 0,000 8,656E-03 0,02678712 ! hexokinase activity GO:0004396 8 8 0,000 8,656E-03 0,02676392 ! neurofilament cytoskeleton GO:0060053 8 8 0,000 8,656E-03 0,02674077 ! guanylate cyclase activity GO:0004383 8 8 0,000 8,656E-03 0,02671766 ! integral to mitochondrial membrane GO:0032592 8 8 0,000 8,656E-03 0,02669459 ! troponin complex GO:0005861 9 8 0,000 8,656E-03 0,02667155 ! smoothened signaling pathway GO:0007224 8 8 0,000 8,656E-03 0,02664856 ! negative regulation of muscle cell differentiation GO:0051148 8 8 0,000 8,656E-03 0,02662561 ! ganglioside metabolic process GO:0001573 8 8 0,000 8,656E-03 0,02660269 ! reflex GO:0060004 11 8 0,000 8,656E-03 0,02657982 ! small protein activating enzyme activity GO:0008641 10 8 0,000 8,656E-03 0,02655699 ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 8,656E-03 0,02653419 ! hemoglobin metabolic process GO:0020027 8 8 0,000 8,656E-03 0,02651143 ! protein targeting to ER GO:0045047 9 8 0,000 8,656E-03 0,02648872 ! positive regulation of survival gene product expression GO:0045885 8 8 0,000 8,656E-03 0,02646604 ! arginine catabolic process GO:0006527 8 8 0,000 8,656E-03 0,0264434 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 8,656E-03 0,0264208 ! malate dehydrogenase activity GO:0016615 8 8 0,000 8,656E-03 0,02639823 ! inner mitochondrial membrane organization GO:0007007 9 8 0,000 8,656E-03 0,02637571 ! telomere maintenance via telomerase GO:0007004 8 8 0,000 8,656E-03 0,02635322 GO:0010833|telomere maintenance via telomere lengthening, ! DNA secondary structure binding GO:0000217 8 8 0,000 8,656E-03 0,02633078 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 9 8 0,000 8,656E-03 0,02630837 ! proline metabolic process GO:0006560 9 8 0,000 8,656E-03 0,026286 ! melanosome membrane GO:0033162 10 8 0,000 8,656E-03 0,02626366 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 8,656E-03 0,02624137 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 8,656E-03 0,02621911 ! melanin metabolic process GO:0006582 9 8 0,000 8,656E-03 0,02619689 ! death receptor activity GO:0005035 8 8 0,000 8,656E-03 0,02617471 ! Golgi lumen GO:0005796 8 8 0,000 8,656E-03 0,02615256 ! smooth endoplasmic reticulum GO:0005790 9 8 0,000 8,656E-03 0,02613046 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 8,656E-03 0,02610839 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 9 8 0,000 8,656E-03 0,02608636 GO:0048500|signal recognition particle, ! Golgi cisterna GO:0031985 9 8 0,000 8,656E-03 0,02606436 ! positive regulation of mesenchymal cell proliferation GO:0002053 8 8 0,000 8,656E-03 0,0260424 ! Rac protein signal transduction GO:0016601 8 8 0,000 8,656E-03 0,02602048 ! positive regulation of calcium ion transport into cytosol GO:0010524 11 8 0,000 8,656E-03 0,0259986 ! lens development in camera-type eye GO:0002088 8 8 0,000 8,656E-03 0,02597675 ! positive regulation of vasodilation GO:0045909 8 8 0,000 8,656E-03 0,02595494 ! intestinal cholesterol absorption GO:0030299 8 8 0,000 8,656E-03 0,02593316 ! negative regulation of muscle contraction GO:0045932 9 8 0,000 8,656E-03 0,02591143 ! positive regulation vascular endothelial growth factor production GO:0010575 8 8 0,000 8,656E-03 0,02588972 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 8 8 0,000 8,656E-03 0,02586806 ! Schwann cell differentiation GO:0014037 8 8 0,000 8,656E-03 0,02584643 ! sodium:dicarboxylate symporter activity GO:0017153 8 8 0,000 8,656E-03 0,02582484 ! axon guidance receptor activity GO:0008046 8 8 0,000 8,656E-03 0,02580328 ! protein targeting to vacuole GO:0006623 8 8 0,000 8,656E-03 0,02578176 ! response to tropane GO:0014073 10 8 0,000 8,656E-03 0,02576028 GO:0042220|response to cocaine, ! purine nucleoside triphosphate catabolic process GO:0009146 8 8 0,000 8,656E-03 0,02573883 ! melanosome localization GO:0032400 8 8 0,000 8,656E-03 0,02571741 ! response to amine stimulus GO:0014075 10 8 0,000 8,656E-03 0,02569604 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 8 8 0,000 8,656E-03 0,02567469 ! sphingomyelin metabolic process GO:0006684 9 8 0,000 8,656E-03 0,02565339 ! regulation of mitochondrial membrane potential GO:0051881 8 8 0,000 8,656E-03 0,02563212 ! synaptic vesicle endocytosis GO:0048488 8 8 0,000 8,656E-03 0,02561088 ! holo TFIIH complex GO:0005675 8 8 0,000 8,656E-03 0,02558968 ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 8,656E-03 0,02556851 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 8 0,000 8,656E-03 0,02554738 ! negative regulation of cytokine secretion GO:0050710 8 8 0,000 8,656E-03 0,02552629 ! regulation of myoblast differentiation GO:0045661 8 8 0,000 8,656E-03 0,02550522 ! vitamin transporter activity GO:0051183 8 8 0,000 8,656E-03 0,0254842 ! positive regulation of erythrocyte differentiation GO:0045648 8 8 0,000 8,656E-03 0,02546321 ! neuromuscular process controlling posture GO:0050884 8 8 0,000 8,656E-03 0,02544225 ! heparan sulfate sulfotransferase activity GO:0034483 8 8 0,000 8,656E-03 0,02542133 ! regulation of epidermal cell differentiation GO:0045604 8 8 0,000 8,656E-03 0,02540044 ! regulation of T-helper 2 cell differentiation GO:0045628 8 8 0,000 8,656E-03 0,02537958 ! positive regulation of T-helper cell differentiation GO:0045624 8 8 0,000 8,656E-03 0,02535876 ! branched chain family amino acid catabolic process GO:0009083 8 8 0,000 8,656E-03 0,02533798 ! regulation of synaptogenesis GO:0051963 8 8 0,000 8,656E-03 0,02531722 ! oocyte differentiation GO:0009994 8 8 0,000 8,656E-03 0,02529651 GO:0048599|oocyte development, ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 8 8 0,000 8,656E-03 0,02527582 GO:0003756|protein disulfide isomerase activity, ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 8,656E-03 0,02525517 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 8 0,000 8,656E-03 0,02523456 ! beta-1,3-galactosyltransferase activity GO:0048531 8 8 0,000 8,656E-03 0,02521397 ! establishment of pigment granule localization GO:0051905 8 8 0,000 8,656E-03 0,02519342 ! regulation of telomere maintenance GO:0032204 8 8 0,000 8,656E-03 0,02517291 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 8,656E-03 0,02515243 ! amino sugar catabolic process GO:0046348 8 8 0,000 8,656E-03 0,02513198 GO:0006043|glucosamine catabolic process, ! regulation of amino acid transport GO:0051955 8 8 0,000 8,656E-03 0,02511156 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 8,656E-03 0,02509118 ! T cell receptor signaling pathway GO:0050852 13 8 0,000 8,656E-03 0,02507083 ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 8 0,000 8,656E-03 0,02505051 ! cholesterol transporter activity GO:0017127 8 8 0,000 8,656E-03 0,02503023 ! GABA receptor binding GO:0050811 8 8 0,000 8,656E-03 0,02500998 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 8 8 0,000 8,656E-03 0,02498976 ! regulation of microtubule polymerization GO:0031113 8 8 0,000 8,656E-03 0,02496957 ! regulation of developmental growth GO:0048638 8 8 0,000 8,656E-03 0,02494942 ! GMP binding GO:0019002 10 8 0,000 8,656E-03 0,0249293 GO:0030553|cGMP binding, ! regulation of epithelial cell differentiation GO:0030856 8 8 0,000 8,656E-03 0,02490921 ! negative regulation of cellular catabolic process GO:0031330 9 8 0,000 8,656E-03 0,02488916 ! prostate gland development GO:0030850 8 8 0,000 8,656E-03 0,02486913 ! 7S RNA binding GO:0008312 9 8 0,000 8,656E-03 0,02484914 ! phosphate transport GO:0006817 9 8 0,000 8,656E-03 0,02482918 ! neutral lipid catabolic process GO:0046461 8 8 0,000 8,656E-03 0,02480925 ! protein phosphorylated amino acid binding GO:0045309 10 8 0,000 8,656E-03 0,02478936 ! reproductive behavior GO:0019098 8 8 0,000 8,656E-03 0,0247695 ! cell volume homeostasis GO:0006884 9 8 0,000 8,656E-03 0,02474966 ! regulation of long-term neuronal synaptic plasticity GO:0048169 8 8 0,000 8,656E-03 0,02472987 ! oligopeptide transport GO:0006857 8 8 0,000 8,656E-03 0,0247101 GO:0015198|oligopeptide transporter activity, ! induction of positive chemotaxis GO:0050930 8 8 0,000 8,656E-03 0,02469036 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 8,656E-03 0,02467066 ! regulation of dopamine metabolic process GO:0042053 8 8 0,000 8,656E-03 0,02465098 GO:0042069|regulation of catecholamine metabolic process, ! regulation of carbohydrate biosynthetic process GO:0043255 8 8 0,000 8,656E-03 0,02463134 ! titin binding GO:0031432 8 8 0,000 8,656E-03 0,02461173 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 8,656E-03 0,02459215 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 8 0,000 8,656E-03 0,0245726 ! bone resorption GO:0045453 8 8 0,000 8,656E-03 0,02455308 ! glycerolipid catabolic process GO:0046503 8 8 0,000 8,656E-03 0,0245336 ! endoderm development GO:0007492 8 8 0,000 8,656E-03 0,02451414 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 8,656E-03 0,02449472 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 8,656E-03 0,02447532 ! astrocyte differentiation GO:0048708 8 8 0,000 8,656E-03 0,02445596 ! embryonic cranial skeleton morphogenesis GO:0048701 8 8 0,000 8,656E-03 0,02443663 ! syncytium formation GO:0006949 8 8 0,000 8,656E-03 0,02441732 ! embryonic eye morphogenesis GO:0048048 10 8 0,000 8,656E-03 0,02439805 ! B cell proliferation GO:0042100 8 8 0,000 8,656E-03 0,02437881 ! mannose metabolic process GO:0006013 10 8 0,000 8,656E-03 0,0243596 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 8 8 0,000 8,656E-03 0,02434042 ! asymmetric protein localization GO:0008105 8 8 0,000 8,656E-03 0,02432127 ! tumor necrosis factor binding GO:0043120 8 8 0,000 8,656E-03 0,02430215 ! synaptic transmission, glutamatergic GO:0035249 9 8 0,000 8,656E-03 0,02428306 ! neuron apoptosis GO:0051402 8 8 0,000 8,656E-03 0,024264 ! macroautophagy GO:0016236 9 8 0,000 8,656E-03 0,02424497 ! Cajal body GO:0015030 8 8 0,000 8,656E-03 0,02422597 ! O-methyltransferase activity GO:0008171 9 8 0,000 8,656E-03 0,02420699 ! H4/H2A histone acetyltransferase complex GO:0043189 9 8 0,000 8,656E-03 0,02418805 ! PcG protein complex GO:0031519 8 8 0,000 8,656E-03 0,02416914 ! ferric iron binding GO:0008199 9 8 0,000 8,656E-03 0,02415026 ! spindle checkpoint GO:0031577 8 8 0,000 8,656E-03 0,02413141 ! G1 DNA damage checkpoint GO:0031571 8 8 0,000 8,656E-03 0,02411258 ! segment specification GO:0007379 8 8 0,000 8,656E-03 0,02409379 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 8,656E-03 0,02407502 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 8,656E-03 0,02405629 ! cellular extravasation GO:0045123 9 8 0,000 8,656E-03 0,02403758 ! pronucleus GO:0045120 8 8 0,000 8,656E-03 0,02401891 ! regulation of insulin receptor signaling pathway GO:0046626 8 8 0,000 8,656E-03 0,02400026 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 8 8 0,000 8,656E-03 0,02398164 ! Rac GTPase activator activity GO:0030675 9 8 0,000 8,656E-03 0,02396305 ! regulation of DNA repair GO:0006282 8 8 0,000 8,656E-03 0,02394449 ! transcription-coupled nucleotide-excision repair GO:0006283 9 8 0,000 8,656E-03 0,02392595 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 8,656E-03 0,02390745 ! antigen processing and presentation of exogenous antigen GO:0019884 9 8 0,000 8,656E-03 0,02388897 ! DNA ligation GO:0006266 8 8 0,000 8,656E-03 0,02387053 ! regulation of T cell differentiation in the thymus GO:0033081 8 8 0,000 8,656E-03 0,02385211 ! negative regulation of systemic arterial blood pressure GO:0003085 8 8 0,000 8,656E-03 0,02383372 ! multicellular organismal aging GO:0010259 8 8 0,000 8,656E-03 0,02381536 ! erythrocyte development GO:0048821 8 8 0,000 8,656E-03 0,02379702 ! interleukin-1 receptor activity GO:0004908 8 8 0,000 8,656E-03 0,02377872 ! positive regulation of monooxygenase activity GO:0032770 8 8 0,000 8,656E-03 0,02376044 ! protein import into peroxisome matrix GO:0016558 8 8 0,000 8,656E-03 0,02374219 ! gamma-tubulin binding GO:0043015 8 8 0,000 8,656E-03 0,02372397 ! ribosome binding GO:0043022 9 8 0,000 8,656E-03 0,02370578 ! NADPH oxidase complex GO:0043020 8 8 0,000 8,656E-03 0,02368761 ! mRNA polyadenylation GO:0006378 8 8 0,000 8,656E-03 0,02366947 ! sodium:amino acid symporter activity GO:0005283 8 8 0,000 8,656E-03 0,02365136 ! adenylyltransferase activity GO:0070566 8 8 0,000 8,656E-03 0,02363328 ! zymogen activation GO:0031638 8 8 0,000 8,656E-03 0,02361523 ! axonal fasciculation GO:0007413 8 8 0,000 8,656E-03 0,0235972 ! T cell homeostasis GO:0043029 9 8 0,000 8,656E-03 0,0235792 ! negative regulation of nuclear division GO:0051784 8 8 0,000 8,656E-03 0,02356123 GO:0045839|negative regulation of mitosis, ! caspase inhibitor activity GO:0043027 8 8 0,000 8,656E-03 0,02354328 ! energy coupled proton transport, against electrochemical gradient GO:0015988 8 8 0,000 8,656E-03 0,02352537 GO:0015991|ATP hydrolysis coupled proton transport, ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 8 8 0,000 8,656E-03 0,02350748 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 8,656E-03 0,02348961 ! thyroid hormone receptor activity GO:0004887 8 8 0,000 8,656E-03 0,02347178 ! wide pore channel activity GO:0022829 8 8 0,000 8,656E-03 0,02345397 ! ligand-regulated transcription factor activity GO:0003706 8 8 0,000 8,656E-03 0,02343619 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 8,656E-03 0,02341843 ! hormone catabolic process GO:0042447 8 8 0,000 8,656E-03 0,02340071 ! positive regulation of ATPase activity GO:0032781 8 8 0,000 8,656E-03 0,023383 ! biogenic amine catabolic process GO:0042402 11 8 0,000 8,656E-03 0,02336533 ! Notch binding GO:0005112 8 8 0,000 8,656E-03 0,02334768 ! death receptor binding GO:0005123 8 8 0,000 8,656E-03 0,02333006 ! ATPase regulator activity GO:0060590 8 8 0,000 8,656E-03 0,02331247 ! pyrimidine base metabolic process GO:0006206 10 8 0,000 8,656E-03 0,0232949 ! epidermal growth factor receptor binding GO:0005154 9 8 0,000 8,656E-03 0,02327736 ! dihydropyridine-sensitive calcium channel activity GO:0015270 8 8 0,000 8,656E-03 0,02325984 ! calcium-release channel activity GO:0015278 8 8 0,000 8,656E-03 0,02324235 ! tubulin-tyrosine ligase activity GO:0004835 8 8 0,000 8,656E-03 0,02322489 ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 8,656E-03 0,02320746 ! nucleus localization GO:0051647 10 8 0,000 8,656E-03 0,02319005 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 8,656E-03 0,02317266 ! negative regulation of immune effector process GO:0002698 12 8 0,000 8,656E-03 0,0231553 ! C-X-C chemokine receptor activity GO:0016494 8 8 0,000 8,656E-03 0,02313797 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 9 9 0,000 9,734E-03 0,02599752 ! respiratory burst GO:0045730 9 9 0,000 9,734E-03 0,02597809 ! telencephalon cell migration GO:0022029 9 9 0,000 9,734E-03 0,02595869 ! 'de novo' posttranslational protein folding GO:0051084 9 9 0,000 9,734E-03 0,02593932 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 9,734E-03 0,02591997 ! cGMP metabolic process GO:0046068 9 9 0,000 9,734E-03 0,02590066 GO:0006182|cGMP biosynthetic process, ! regulation of epidermal growth factor receptor activity GO:0007176 9 9 0,000 9,734E-03 0,02588137 GO:0010469|regulation of receptor activity, ! inositol trisphosphate phosphatase activity GO:0046030 11 9 0,000 9,734E-03 0,02586212 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! axon part GO:0033267 12 9 0,000 9,734E-03 0,02584289 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 9 9 0,000 9,734E-03 0,02582369 ! RNA polyadenylation GO:0043631 9 9 0,000 9,734E-03 0,02580452 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 9 0,000 9,734E-03 0,02578537 ! regulation of receptor-mediated endocytosis GO:0048259 9 9 0,000 9,734E-03 0,02576626 ! artery development GO:0060840 9 9 0,000 9,734E-03 0,02574717 GO:0048844|artery morphogenesis, ! photoreceptor cell development GO:0042461 12 9 0,000 9,734E-03 0,02572812 GO:0046530|photoreceptor cell differentiation, ! microtubule bundle formation GO:0001578 9 9 0,000 9,734E-03 0,02570909 ! middle ear morphogenesis GO:0042474 9 9 0,000 9,734E-03 0,02569009 ! regulation of mesenchymal cell proliferation GO:0010464 9 9 0,000 9,734E-03 0,02567111 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 12 9 0,000 9,734E-03 0,02565217 GO:0046330|positive regulation of JNK cascade, ! positive regulation of heart contraction GO:0045823 10 9 0,000 9,734E-03 0,02563325 ! lung alveolus development GO:0048286 9 9 0,000 9,734E-03 0,02561436 ! ciliary or flagellar motility GO:0001539 9 9 0,000 9,734E-03 0,0255955 ! beta-amyloid binding GO:0001540 10 9 0,000 9,734E-03 0,02557666 ! pathogenesis GO:0009405 9 9 0,000 9,734E-03 0,02555786 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 10 9 0,000 9,734E-03 0,02553908 ! regulated secretory pathway GO:0045055 9 9 0,000 9,734E-03 0,02552033 ! estrogen receptor binding GO:0030331 9 9 0,000 9,734E-03 0,0255016 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 10 9 0,000 9,734E-03 0,02548291 ! regulation of defense response to virus by virus GO:0050690 9 9 0,000 9,734E-03 0,02546424 ! histidine metabolic process GO:0006547 9 9 0,000 9,734E-03 0,0254456 GO:0009075|histidine family amino acid metabolic process, ! L-phenylalanine metabolic process GO:0006558 10 9 0,000 9,734E-03 0,02542698 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 9 9 0,000 9,734E-03 0,0254084 GO:0005978|glycogen biosynthetic process, ! V(D)J recombination GO:0033151 9 9 0,000 9,734E-03 0,02538984 ! nucleobase biosynthetic process GO:0046112 11 9 0,000 9,734E-03 0,0253713 ! regulation of Cdc42 protein signal transduction GO:0032489 9 9 0,000 9,734E-03 0,0253528 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of calcium ion transport into cytosol GO:0010522 12 9 0,000 9,734E-03 0,02533432 ! entry into host cell GO:0030260 9 9 0,000 9,734E-03 0,02531587 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 9 9 0,000 9,734E-03 0,02529744 ! regulation of lipoprotein lipase activity GO:0051004 9 9 0,000 9,734E-03 0,02527904 ! retinoic acid metabolic process GO:0042573 9 9 0,000 9,734E-03 0,02526067 ! retinol metabolic process GO:0042572 9 9 0,000 9,734E-03 0,02524233 ! behavioral fear response GO:0001662 9 9 0,000 9,734E-03 0,02522401 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 10 9 0,000 9,734E-03 0,02520572 ! regulation of vascular endothelial growth factor production GO:0010574 9 9 0,000 9,734E-03 0,02518745 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 9 9 0,000 9,734E-03 0,02516921 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! motor axon guidance GO:0008045 9 9 0,000 9,734E-03 0,025151 ! regulation of gliogenesis GO:0014013 9 9 0,000 9,734E-03 0,02513282 GO:0045685|regulation of glial cell differentiation, ! recycling endosome membrane GO:0055038 10 9 0,000 9,734E-03 0,02511466 ! pigment granule localization GO:0051875 9 9 0,000 9,734E-03 0,02509652 ! platelet-derived growth factor binding GO:0048407 10 9 0,000 9,734E-03 0,02507842 ! glycosphingolipid biosynthetic process GO:0006688 9 9 0,000 9,734E-03 0,02506034 ! nucleoside diphosphate metabolic process GO:0009132 10 9 0,000 9,734E-03 0,02504228 ! phosphoinositide 3-kinase cascade GO:0014065 9 9 0,000 9,734E-03 0,02502425 ! cell wall macromolecule catabolic process GO:0016998 10 9 0,000 9,734E-03 0,02500625 ! purine ribonucleotide catabolic process GO:0009154 9 9 0,000 9,734E-03 0,02498827 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 9 9 0,000 9,734E-03 0,02497032 ! nitric oxide metabolic process GO:0046209 9 9 0,000 9,734E-03 0,02495239 GO:0006809|nitric oxide biosynthetic process, ! mismatch repair complex GO:0032300 9 9 0,000 9,734E-03 0,02493449 ! icosanoid secretion GO:0032309 9 9 0,000 9,734E-03 0,02491662 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 10 9 0,000 9,734E-03 0,02489877 GO:0010092|specification of organ identity, ! retinal ganglion cell axon guidance GO:0031290 9 9 0,000 9,734E-03 0,02488095 ! morphogenesis of a polarized epithelium GO:0001738 9 9 0,000 9,734E-03 0,02486315 ! sterol catabolic process GO:0016127 9 9 0,000 9,734E-03 0,02484538 GO:0006707|cholesterol catabolic process, ! prophase GO:0051324 9 9 0,000 9,734E-03 0,02482763 ! peptidyl-lysine modification GO:0018205 9 9 0,000 9,734E-03 0,02480991 ! pancreatic ribonuclease activity GO:0004522 9 9 0,000 9,734E-03 0,02479221 ! clathrin coat of coated pit GO:0030132 12 9 0,000 9,734E-03 0,02477454 ! SNARE complex GO:0031201 10 9 0,000 9,734E-03 0,0247569 ! ubiquinone metabolic process GO:0006743 10 9 0,000 9,734E-03 0,02473928 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! snRNA binding GO:0017069 9 9 0,000 9,734E-03 0,02472168 ! regulation of macrophage differentiation GO:0045649 9 9 0,000 9,734E-03 0,02470411 ! regulation of osteoclast differentiation GO:0045670 10 9 0,000 9,734E-03 0,02468657 ! positive regulation of neuron differentiation GO:0045666 9 9 0,000 9,734E-03 0,02466905 ! negative regulation of lymphocyte differentiation GO:0045620 9 9 0,000 9,734E-03 0,02465155 ! methionine biosynthetic process GO:0009086 10 9 0,000 9,734E-03 0,02463408 ! peptidoglycan binding GO:0042834 9 9 0,000 9,734E-03 0,02461663 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 9,734E-03 0,02459921 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! pyridine nucleotide biosynthetic process GO:0019363 9 9 0,000 9,734E-03 0,02458181 ! intramolecular transferase activity, phosphotransferases GO:0016868 9 9 0,000 9,734E-03 0,02456444 ! cholesterol efflux GO:0033344 9 9 0,000 9,734E-03 0,02454709 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 9 9 0,000 9,734E-03 0,02452977 ! metalloenzyme inhibitor activity GO:0048551 10 9 0,000 9,734E-03 0,02451247 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! leukocyte mediated cytotoxicity GO:0001909 9 9 0,000 9,734E-03 0,0244952 ! anterior/posterior axis specification GO:0009948 9 9 0,000 9,734E-03 0,02447795 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 9,734E-03 0,02446072 ! detection of calcium ion GO:0005513 10 9 0,000 9,734E-03 0,02444352 ! negative regulation of glucose import GO:0046325 9 9 0,000 9,734E-03 0,02442634 GO:0010829|negative regulation of glucose transport, ! regulation of fibrinolysis GO:0051917 9 9 0,000 9,734E-03 0,02440919 ! trophectodermal cell differentiation GO:0001829 9 9 0,000 9,734E-03 0,02439206 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 9 0,000 9,734E-03 0,02437495 ! hydrolase activity, acting on ether bonds GO:0016801 9 9 0,000 9,734E-03 0,02435787 ! desmosome GO:0030057 9 9 0,000 9,734E-03 0,02434082 ! prepulse inhibition GO:0060134 9 9 0,000 9,734E-03 0,02432378 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 9 0,000 9,734E-03 0,02430677 ! negative regulation of B cell activation GO:0050869 9 9 0,000 9,734E-03 0,02428979 ! anchoring collagen GO:0030934 9 9 0,000 9,734E-03 0,02427282 ! axon extension GO:0048675 10 9 0,000 9,734E-03 0,02425589 ! neuron fate specification GO:0048665 9 9 0,000 9,734E-03 0,02423897 ! positive regulation of glucose metabolic process GO:0010907 9 9 0,000 9,734E-03 0,02422208 ! cortical actin cytoskeleton organization GO:0030866 9 9 0,000 9,734E-03 0,02420521 ! virus-host interaction GO:0019048 13 9 0,000 9,734E-03 0,02418837 ! rough endoplasmic reticulum membrane GO:0030867 9 9 0,000 9,734E-03 0,02417155 ! pentose-phosphate shunt GO:0006098 9 9 0,000 9,734E-03 0,02415475 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 9,734E-03 0,02413798 ! DNA bending activity GO:0008301 9 9 0,000 9,734E-03 0,02412122 ! social behavior GO:0035176 9 9 0,000 9,734E-03 0,0241045 ! secondary active sulfate transmembrane transporter activity GO:0008271 9 9 0,000 9,734E-03 0,02408779 ! dipeptidyl-peptidase activity GO:0008239 11 9 0,000 9,734E-03 0,02407111 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 9,734E-03 0,02405445 ! very-low-density lipoprotein particle GO:0034361 9 9 0,000 9,734E-03 0,02403782 GO:0034385|triglyceride-rich lipoprotein particle, ! high-density lipoprotein particle GO:0034364 9 9 0,000 9,734E-03 0,02402121 ! amyloid precursor protein metabolic process GO:0042982 10 9 0,000 9,734E-03 0,02400462 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 11 9 0,000 9,734E-03 0,02398805 ! blood vessel remodeling GO:0001974 10 9 0,000 9,734E-03 0,02397151 ! C-X-C chemokine binding GO:0019958 9 9 0,000 9,734E-03 0,02395499 ! 3'-5'-exoribonuclease activity GO:0000175 9 9 0,000 9,734E-03 0,02393849 ! exosome (RNase complex) GO:0000178 9 9 0,000 9,734E-03 0,02392201 ! inositol phosphate-mediated signaling GO:0048016 9 9 0,000 9,734E-03 0,02390556 ! DNA N-glycosylase activity GO:0019104 9 9 0,000 9,734E-03 0,02388913 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 9 9 0,000 9,734E-03 0,02387272 GO:0033549|MAP kinase phosphatase activity, ! ER overload response GO:0006983 11 9 0,000 9,734E-03 0,02385634 ! zinc ion transmembrane transporter activity GO:0005385 9 9 0,000 9,734E-03 0,02383998 ! glucose transmembrane transporter activity GO:0005355 9 9 0,000 9,734E-03 0,02382364 ! retrograde transport, endosome to Golgi GO:0042147 10 9 0,000 9,734E-03 0,02380732 ! phagocytosis, engulfment GO:0006911 10 9 0,000 9,734E-03 0,02379102 ! neurotransmitter biosynthetic process GO:0042136 10 9 0,000 9,734E-03 0,02377475 ! carbohydrate phosphatase activity GO:0019203 9 9 0,000 9,734E-03 0,0237585 ! glutathione peroxidase activity GO:0004602 9 9 0,000 9,734E-03 0,02374227 ! acyl-CoA thioesterase activity GO:0016291 9 9 0,000 9,734E-03 0,02372606 ! lysophospholipase activity GO:0004622 9 9 0,000 9,734E-03 0,02370988 ! brain morphogenesis GO:0048854 9 9 0,000 9,734E-03 0,02369372 ! apolipoprotein binding GO:0034185 9 9 0,000 9,734E-03 0,02367758 ! synaptic vesicle membrane GO:0030672 9 9 0,000 9,734E-03 0,02366146 ! RNA-dependent DNA replication GO:0006278 9 9 0,000 9,734E-03 0,02364536 ! positive regulation of systemic arterial blood pressure GO:0003084 10 9 0,000 9,734E-03 0,02362929 ! kinesin binding GO:0019894 9 9 0,000 9,734E-03 0,02361324 ! nucleoside bisphosphate metabolic process GO:0033865 10 9 0,000 9,734E-03 0,02359721 ! renal water homeostasis GO:0003091 9 9 0,000 9,734E-03 0,0235812 ! positive regulation of interleukin-6 production GO:0032755 9 9 0,000 9,734E-03 0,02356521 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 9,734E-03 0,02354924 ! histone methylation GO:0016571 10 9 0,000 9,734E-03 0,0235333 ! mRNA cleavage GO:0006379 9 9 0,000 9,734E-03 0,02351738 ! negative regulation of tumor necrosis factor production GO:0032720 9 9 0,000 9,734E-03 0,02350148 ! regulation of transcription from RNA polymerase III promoter GO:0006359 9 9 0,000 9,734E-03 0,0234856 ! sarcoplasmic reticulum membrane GO:0033017 10 9 0,000 9,734E-03 0,02346974 ! opioid receptor activity GO:0004985 9 9 0,000 9,734E-03 0,0234539 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 9,734E-03 0,02343809 ! salivary gland development GO:0007431 10 9 0,000 9,734E-03 0,02342229 ! glucosidase activity GO:0015926 10 9 0,000 9,734E-03 0,02340652 ! adrenoceptor activity GO:0004935 11 9 0,000 9,734E-03 0,02339077 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 9 9 0,000 9,734E-03 0,02337504 ! positive regulation of leukocyte migration GO:0002687 9 9 0,000 9,734E-03 0,02335933 ! purine base metabolic process GO:0006144 11 9 0,000 9,734E-03 0,02334364 ! mRNA 3'-UTR binding GO:0003730 9 9 0,000 9,734E-03 0,02332798 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 9 9 0,000 9,734E-03 0,02331233 ! receptor inhibitor activity GO:0030547 9 9 0,000 9,734E-03 0,02329671 GO:0048019|receptor antagonist activity, ! negative regulation of BMP signaling pathway GO:0030514 9 9 0,000 9,734E-03 0,0232811 ! ionotropic glutamate receptor complex GO:0008328 11 9 0,000 9,734E-03 0,02326552 ! transforming growth factor beta receptor binding GO:0005160 9 9 0,000 9,734E-03 0,02324996 ! palmitoyltransferase activity GO:0016409 9 9 0,000 9,734E-03 0,02323442 ! arylsulfatase activity GO:0004065 9 9 0,000 9,734E-03 0,02321889 ! phospholipase inhibitor activity GO:0004859 9 9 0,000 9,734E-03 0,02320339 ! behavioral response to nicotine GO:0035095 9 9 0,000 9,734E-03 0,02318792 ! adenylate kinase activity GO:0004017 10 9 0,000 9,734E-03 0,02317246 ! alcohol dehydrogenase (NAD) activity GO:0004022 9 9 0,000 9,734E-03 0,02315702 ! mitochondrion localization GO:0051646 9 9 0,000 9,734E-03 0,0231416 ! localization within membrane GO:0051668 9 9 0,000 9,734E-03 0,0231262 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 10 0,000 0,01080961 0,02566564 ! lipid particle GO:0005811 10 10 0,000 0,01080961 0,02564858 ! myotube differentiation GO:0014902 10 10 0,000 0,01080961 0,02563155 ! generation of neurons in the forebrain GO:0021872 11 10 0,000 0,01080961 0,02561455 ! regulation of cellular amine metabolic process GO:0033238 10 10 0,000 0,01080961 0,02559756 ! synapsis GO:0007129 10 10 0,000 0,01080961 0,0255806 GO:0070192|chromosome organization involved in meiosis, ! filopodium assembly GO:0046847 12 10 0,000 0,01080961 0,02556366 ! UTP metabolic process GO:0046051 10 10 0,000 0,01080961 0,02554674 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 10 10 0,000 0,01080961 0,02552984 ! COPI coating of Golgi vesicle GO:0048205 10 10 0,000 0,01080961 0,02551297 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 10 10 0,000 0,01080961 0,02549612 ! platelet alpha granule membrane GO:0031092 11 10 0,000 0,01080961 0,02547929 ! macromolecule transmembrane transporter activity GO:0022884 10 10 0,000 0,01080961 0,02546248 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! lipoprotein receptor binding GO:0070325 10 10 0,000 0,01080961 0,0254457 GO:0050750|low-density lipoprotein receptor binding, ! thyroid hormone receptor coactivator activity GO:0030375 10 10 0,000 0,01080961 0,02542893 GO:0010861|thyroid hormone receptor activator activity, ! auditory receptor cell differentiation GO:0042491 11 10 0,000 0,01080961 0,02541219 ! regulation of chemokine biosynthetic process GO:0045073 10 10 0,000 0,01080961 0,02539547 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 10 10 0,000 0,01080961 0,02537878 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 0,01080961 0,0253621 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 10 10 0,000 0,01080961 0,02534545 ! nucleotide-sugar metabolic process GO:0009225 11 10 0,000 0,01080961 0,02532882 ! regulation of catecholamine secretion GO:0050433 10 10 0,000 0,01080961 0,02531221 ! melanocyte differentiation GO:0030318 10 10 0,000 0,01080961 0,02529562 GO:0050931|pigment cell differentiation, ! ER-Golgi intermediate compartment membrane GO:0033116 10 10 0,000 0,01080961 0,02527906 ! deoxyribonucleotide catabolic process GO:0009264 10 10 0,000 0,01080961 0,02526251 ! L-serine metabolic process GO:0006563 11 10 0,000 0,01080961 0,02524599 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 10 10 0,000 0,01080961 0,02522949 ! lipase inhibitor activity GO:0055102 10 10 0,000 0,01080961 0,02521301 ! autophagic vacuole GO:0005776 11 10 0,000 0,01080961 0,02519655 ! NAD metabolic process GO:0019674 10 10 0,000 0,01080961 0,02518012 ! stereocilium GO:0032420 10 10 0,000 0,01080961 0,0251637 GO:0032421|stereocilium bundle, ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 0,01080961 0,02514731 ! regulation of sodium ion transport GO:0002028 10 10 0,000 0,01080961 0,02513094 ! forebrain cell migration GO:0021885 10 10 0,000 0,01080961 0,02511459 ! organelle subcompartment GO:0031984 11 10 0,000 0,01080961 0,02509826 ! chondrocyte differentiation GO:0002062 10 10 0,000 0,01080961 0,02508195 ! negative regulation of ossification GO:0030279 10 10 0,000 0,01080961 0,02506566 ! regulation of smoothened signaling pathway GO:0008589 10 10 0,000 0,01080961 0,0250494 ! heparan sulfate proteoglycan metabolic process GO:0030201 10 10 0,000 0,01080961 0,02503315 ! phosphatidylcholine biosynthetic process GO:0006656 12 10 0,000 0,01080961 0,02501693 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 10 10 0,000 0,01080961 0,02500073 ! protein homotetramerization GO:0051289 11 10 0,000 0,01080961 0,02498454 ! oligodendrocyte development GO:0014003 10 10 0,000 0,01080961 0,02496838 ! positive regulation of phagocytosis GO:0050766 10 10 0,000 0,01080961 0,02495224 ! response to dsRNA GO:0043331 10 10 0,000 0,01080961 0,02493612 ! mismatch repair complex binding GO:0032404 11 10 0,000 0,01080961 0,02492003 ! snRNA metabolic process GO:0016073 10 10 0,000 0,01080961 0,02490395 GO:0016180|snRNA processing, ! cranial nerve development GO:0021545 10 10 0,000 0,01080961 0,02488789 ! fucose catabolic process GO:0019317 11 10 0,000 0,01080961 0,02487186 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 10 10 0,000 0,01080961 0,02485584 ! retinal binding GO:0016918 10 10 0,000 0,01080961 0,02483985 ! leukocyte activation during immune response GO:0002366 10 10 0,000 0,01080961 0,02482387 GO:0002263|cell activation during immune response, ! cerebellum morphogenesis GO:0021587 11 10 0,000 0,01080961 0,02480792 GO:0021696|cerebellar cortex morphogenesis, ! photoreceptor outer segment GO:0001750 10 10 0,000 0,01080961 0,02479198 ! negative regulation of MAPKKK cascade GO:0043409 10 10 0,000 0,01080961 0,02477607 ! regulation of T-helper 2 type immune response GO:0002828 10 10 0,000 0,01080961 0,02476018 ! ribonuclease P activity GO:0004526 10 10 0,000 0,01080961 0,02474431 ! midbrain development GO:0030901 10 10 0,000 0,01080961 0,02472846 ! musculoskeletal movement GO:0050881 10 10 0,000 0,01080961 0,02471263 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 10 10 0,000 0,01080961 0,02469681 ! regulation of T-helper cell differentiation GO:0045622 10 10 0,000 0,01080961 0,02468102 ! fatty-acid ligase activity GO:0015645 10 10 0,000 0,01080961 0,02466525 GO:0004467|long-chain-fatty-acid-CoA ligase activity, ! regulation of mRNA stability GO:0043488 10 10 0,000 0,01080961 0,0246495 ! quaternary ammonium group transport GO:0015697 10 10 0,000 0,01080961 0,02463377 ! regulation of RNA splicing GO:0043484 10 10 0,000 0,01080961 0,02461806 ! embryonic gut development GO:0048566 10 10 0,000 0,01080961 0,02460237 ! positive regulation of amine transport GO:0051954 10 10 0,000 0,01080961 0,0245867 ! defense response to Gram-positive bacterium GO:0050830 10 10 0,000 0,01080961 0,02457105 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,01080961 0,02455542 ! lysogeny GO:0030069 10 10 0,000 0,01080961 0,02453981 GO:0019047|provirus integration, ! lamellipodium assembly GO:0030032 11 10 0,000 0,01080961 0,02452422 ! establishment of cell polarity GO:0030010 10 10 0,000 0,01080961 0,02450865 ! regulation of synapse organization GO:0050807 10 10 0,000 0,01080961 0,0244931 ! cell wall macromolecule metabolic process GO:0044036 11 10 0,000 0,01080961 0,02447757 ! acyl-CoA binding GO:0000062 10 10 0,000 0,01080961 0,02446205 ! negative regulation of muscle development GO:0048635 11 10 0,000 0,01080961 0,02444656 GO:0045843|negative regulation of striated muscle development, ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 0,01080961 0,02443109 ! GDP binding GO:0019003 10 10 0,000 0,01080961 0,02441564 ! photoreceptor activity GO:0009881 10 10 0,000 0,01080961 0,0244002 ! somatic diversification of immune receptors via somatic mutation GO:0002566 10 10 0,000 0,01080961 0,02438479 GO:0016446|somatic hypermutation of immunoglobulin genes, ! cortical cytoskeleton organization GO:0030865 10 10 0,000 0,01080961 0,02436939 ! nitric-oxide synthase binding GO:0050998 11 10 0,000 0,01080961 0,02435402 ! nuclear chromosome, telomeric region GO:0000784 10 10 0,000 0,01080961 0,02433866 ! nucleotidase activity GO:0008252 10 10 0,000 0,01080961 0,02432333 ! detection of mechanical stimulus GO:0050982 10 10 0,000 0,01080961 0,02430801 ! protein complex disassembly GO:0043241 11 10 0,000 0,01080961 0,02429271 GO:0043624|cellular protein complex disassembly, ! androgen metabolic process GO:0008209 10 10 0,000 0,01080961 0,02427743 ! lateral plasma membrane GO:0016328 10 10 0,000 0,01080961 0,02426217 ! estrogen metabolic process GO:0008210 10 10 0,000 0,01080961 0,02424693 ! nucleocytoplasmic transporter activity GO:0005487 10 10 0,000 0,01080961 0,02423171 ! retinol dehydrogenase activity GO:0004745 10 10 0,000 0,01080961 0,02421651 ! negative regulation of cell-matrix adhesion GO:0001953 12 10 0,000 0,01080961 0,02420133 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 11 10 0,000 0,01080961 0,02418617 ! interleukin-1 binding GO:0019966 10 10 0,000 0,01080961 0,02417102 ! endothelial cell differentiation GO:0045446 10 10 0,000 0,01080961 0,0241559 ! cullin-RING ubiquitin ligase complex GO:0031461 10 10 0,000 0,01080961 0,02414079 ! acid phosphatase activity GO:0003993 10 10 0,000 0,01080961 0,0241257 ! sodium:potassium-exchanging ATPase activity GO:0005391 11 10 0,000 0,01080961 0,02411063 ! telomeric DNA binding GO:0042162 11 10 0,000 0,01080961 0,02409558 ! regulation of intracellular pH GO:0051453 10 10 0,000 0,01080961 0,02408055 ! lipid digestion GO:0044241 10 10 0,000 0,01080961 0,02406554 ! multicellular organism growth GO:0035264 10 10 0,000 0,01080961 0,02405054 ! receptor clustering GO:0043113 10 10 0,000 0,01080961 0,02403557 ! L-glutamate transmembrane transporter activity GO:0005313 10 10 0,000 0,01080961 0,02402061 GO:0015172|acidic amino acid transmembrane transporter activity, ! brush border membrane GO:0031526 11 10 0,000 0,01080961 0,02400567 ! adult heart development GO:0007512 12 10 0,000 0,01080961 0,02399075 ! actin cytoskeleton reorganization GO:0031532 12 10 0,000 0,01080961 0,02397585 ! signalosome GO:0008180 10 10 0,000 0,01080961 0,02396097 ! prefoldin complex GO:0016272 10 10 0,000 0,01080961 0,0239461 ! neuromuscular junction GO:0031594 10 10 0,000 0,01080961 0,02393126 ! regulation of bone resorption GO:0045124 11 10 0,000 0,01080961 0,02391643 ! positive regulation of peptide secretion GO:0002793 10 10 0,000 0,01080961 0,02390162 ! alpha-beta T cell differentiation GO:0046632 11 10 0,000 0,01080961 0,02388683 ! negative regulation of myeloid leukocyte differentiation GO:0002762 10 10 0,000 0,01080961 0,02387206 ! positive regulation of T cell mediated immunity GO:0002711 14 10 0,000 0,01080961 0,02385731 ! taste receptor activity GO:0008527 10 10 0,000 0,01080961 0,02384257 ! endocytic vesicle membrane GO:0030666 10 10 0,000 0,01080961 0,02382785 ! regulation of interleukin-12 production GO:0032655 10 10 0,000 0,01080961 0,02381315 ! ribosome assembly GO:0042255 10 10 0,000 0,01080961 0,02379847 ! DNA methylation GO:0006306 12 10 0,000 0,01080961 0,02378381 GO:0006305|DNA alkylation, ! protein-hormone receptor activity GO:0016500 10 10 0,000 0,01080961 0,02376916 ! bile acid transmembrane transporter activity GO:0015125 10 10 0,000 0,01080961 0,02375454 ! proteasome accessory complex GO:0022624 11 10 0,000 0,01080961 0,02373993 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 13 10 0,000 0,01080961 0,02372534 ! prostaglandin receptor activity GO:0004955 11 10 0,000 0,01080961 0,02371076 ! regulation of isotype switching GO:0045191 14 10 0,000 0,01080961 0,02369621 ! peptide transporter activity GO:0015197 10 10 0,000 0,01080961 0,02368167 ! regulation of leukocyte migration GO:0002685 10 10 0,000 0,01080961 0,02366715 ! retinoid-X receptor activity GO:0004886 10 10 0,000 0,01080961 0,02365265 ! GTPase inhibitor activity GO:0005095 10 10 0,000 0,01080961 0,02363816 ! pattern recognition receptor activity GO:0008329 10 10 0,000 0,01080961 0,0236237 ! gamma-tubulin complex GO:0000930 12 10 0,000 0,01080961 0,02360925 ! germ cell migration GO:0008354 10 10 0,000 0,01080961 0,02359482 ! regulation of organic acid transport GO:0032890 10 10 0,000 0,01080961 0,0235804 ! negative regulation of mast cell proliferation GO:0070667 10 10 0,000 0,01080961 0,02356601 GO:0042130|negative regulation of T cell proliferation, ! cardiac cell differentiation GO:0035051 11 10 0,000 0,01080961 0,02355163 ! amiloride-sensitive sodium channel activity GO:0015280 10 10 0,000 0,01080961 0,02353727 ! sterol transporter activity GO:0015248 10 10 0,000 0,01080961 0,02352293 ! regulation of embryonic development GO:0045995 11 10 0,000 0,01080961 0,0235086 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 11 11 0,000 0,01188453 0,02583058 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 11 0,000 0,01188453 0,02581487 ! negative regulation of blood pressure GO:0045776 11 11 0,000 0,01188453 0,02579917 ! RNA cap binding GO:0000339 12 11 0,000 0,01188453 0,0257835 ! CTP metabolic process GO:0046036 12 11 0,000 0,01188453 0,02576785 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 11 0,000 0,01188453 0,02575221 ! response to pain GO:0048265 11 11 0,000 0,01188453 0,02573659 ! axonemal dynein complex GO:0005858 11 11 0,000 0,01188453 0,02572099 ! eukaryotic translation initiation factor 3 complex GO:0005852 11 11 0,000 0,01188453 0,02570542 ! dopamine receptor signaling pathway GO:0007212 13 11 0,000 0,01188453 0,02568986 ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 11 0,000 0,01188453 0,02567431 ! endocrine pancreas development GO:0031018 11 11 0,000 0,01188453 0,02565879 ! regulation of interferon-gamma biosynthetic process GO:0045072 12 11 0,000 0,01188453 0,02564329 ! regulation of exit from mitosis GO:0007096 11 11 0,000 0,01188453 0,0256278 ! chylomicron GO:0042627 11 11 0,000 0,01188453 0,02561234 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 11 11 0,000 0,01188453 0,02559689 ! glycolipid biosynthetic process GO:0009247 11 11 0,000 0,01188453 0,02558146 ! transforming growth factor beta binding GO:0050431 11 11 0,000 0,01188453 0,02556605 ! glutamate metabolic process GO:0006536 12 11 0,000 0,01188453 0,02555066 ! ribonucleotide catabolic process GO:0009261 11 11 0,000 0,01188453 0,02553528 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 0,01188453 0,02551993 ! vascular endothelial growth factor receptor activity GO:0005021 11 11 0,000 0,01188453 0,02550459 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 11 11 0,000 0,01188453 0,02548927 GO:0045125|bioactive lipid receptor activity, ! Rac GTPase binding GO:0048365 11 11 0,000 0,01188453 0,02547397 ! epithelial cell development GO:0002064 11 11 0,000 0,01188453 0,02545869 ! filamentous actin GO:0031941 11 11 0,000 0,01188453 0,02544343 ! temperature homeostasis GO:0001659 11 11 0,000 0,01188453 0,02542819 ! structural constituent of epidermis GO:0030280 13 11 0,000 0,01188453 0,02541296 ! protein targeting to peroxisome GO:0006625 11 11 0,000 0,01188453 0,02539775 ! spectrin GO:0008091 11 11 0,000 0,01188453 0,02538256 ! cytoskeletal adaptor activity GO:0008093 14 11 0,000 0,01188453 0,02536739 ! negative regulation of axonogenesis GO:0050771 13 11 0,000 0,01188453 0,02535223 ! regulation of phagocytosis GO:0050764 11 11 0,000 0,01188453 0,0253371 ! nucleoside triphosphate catabolic process GO:0009143 11 11 0,000 0,01188453 0,02532198 ! synaptic vesicle exocytosis GO:0016079 12 11 0,000 0,01188453 0,02530688 ! regulation of B cell differentiation GO:0045577 15 11 0,000 0,01188453 0,0252918 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 11 11 0,000 0,01188453 0,02527674 ! basal lamina GO:0005605 12 11 0,000 0,01188453 0,02526169 ! gastrulation with mouth forming second GO:0001702 12 11 0,000 0,01188453 0,02524666 ! spinal cord motor neuron differentiation GO:0021522 11 11 0,000 0,01188453 0,02523165 ! hindbrain morphogenesis GO:0021575 13 11 0,000 0,01188453 0,02521666 ! regulation of hormone metabolic process GO:0032350 12 11 0,000 0,01188453 0,02520169 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 11 0,000 0,01188453 0,02518673 GO:0050706|regulation of interleukin-1 beta secretion, ! COPI vesicle coat GO:0030126 11 11 0,000 0,01188453 0,02517179 GO:0030663|COPI coated vesicle membrane, ! clathrin coat of trans-Golgi network vesicle GO:0030130 14 11 0,000 0,01188453 0,02515687 ! tRNA-specific ribonuclease activity GO:0004549 11 11 0,000 0,01188453 0,02514197 ! cofactor transporter activity GO:0051184 11 11 0,000 0,01188453 0,02512708 ! cobalt ion binding GO:0050897 11 11 0,000 0,01188453 0,02511221 ! pseudouridine synthase activity GO:0009982 12 11 0,000 0,01188453 0,02509736 ! aromatic amino acid family catabolic process GO:0009074 12 11 0,000 0,01188453 0,02508253 ! serine family amino acid biosynthetic process GO:0009070 11 11 0,000 0,01188453 0,02506771 ! histone deacetylase binding GO:0042826 11 11 0,000 0,01188453 0,02505292 ! thymus development GO:0048538 12 11 0,000 0,01188453 0,02503814 ! spleen development GO:0048536 12 11 0,000 0,01188453 0,02502337 ! regulation of RNA stability GO:0043487 11 11 0,000 0,01188453 0,02500863 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 12 11 0,000 0,01188453 0,0249939 ! acid-thiol ligase activity GO:0016878 11 11 0,000 0,01188453 0,02497919 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 11 11 0,000 0,01188453 0,02496449 ! blastocyst formation GO:0001825 11 11 0,000 0,01188453 0,02494982 ! cerebellar cortex development GO:0021695 12 11 0,000 0,01188453 0,02493516 ! ADP binding GO:0043531 11 11 0,000 0,01188453 0,02492052 ! folic acid binding GO:0005542 11 11 0,000 0,01188453 0,02490589 ! FK506 binding GO:0005528 11 11 0,000 0,01188453 0,02489129 GO:0005527|macrolide binding, ! defense response to fungus GO:0050832 11 11 0,000 0,01188453 0,02487669 ! extracellular matrix binding GO:0050840 13 11 0,000 0,01188453 0,02486212 ! microspike assembly GO:0030035 13 11 0,000 0,01188453 0,02484757 ! cytoplasmic sequestering of protein GO:0051220 11 11 0,000 0,01188453 0,02483303 ! regulation of synapse structure and activity GO:0050803 11 11 0,000 0,01188453 0,0248185 ! organ formation GO:0048645 12 11 0,000 0,01188453 0,024804 ! embryonic hindlimb morphogenesis GO:0035116 11 11 0,000 0,01188453 0,02478951 ! embryonic forelimb morphogenesis GO:0035115 11 11 0,000 0,01188453 0,02477504 ! cellular copper ion homeostasis GO:0006878 12 11 0,000 0,01188453 0,02476058 ! glycosaminoglycan catabolic process GO:0006027 11 11 0,000 0,01188453 0,02474615 ! Golgi vesicle budding GO:0048194 11 11 0,000 0,01188453 0,02473173 ! regulation of positive chemotaxis GO:0050926 11 11 0,000 0,01188453 0,02471732 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 11 11 0,000 0,01188453 0,02470293 ! ion channel inhibitor activity GO:0008200 13 11 0,000 0,01188453 0,02468856 GO:0016248|channel inhibitor activity, ! positive regulation of transcription factor import into nucleus GO:0042993 12 11 0,000 0,01188453 0,02467421 ! MAP kinase kinase activity GO:0004708 11 11 0,000 0,01188453 0,02465987 GO:0004712|protein serine/threonine/tyrosine kinase activity, ! cation:amino acid symporter activity GO:0005416 11 11 0,000 0,01188453 0,02464555 ! mannosyltransferase activity GO:0000030 11 11 0,000 0,01188453 0,02463125 ! cAMP-dependent protein kinase activity GO:0004691 11 11 0,000 0,01188453 0,02461696 ! FMN binding GO:0010181 11 11 0,000 0,01188453 0,02460269 ! response to X-ray GO:0010165 12 11 0,000 0,01188453 0,02458844 ! focal adhesion formation GO:0048041 13 11 0,000 0,01188453 0,0245742 ! actin polymerization or depolymerization GO:0008154 13 11 0,000 0,01188453 0,02455998 ! substrate-bound cell migration GO:0006929 11 11 0,000 0,01188453 0,02454577 ! integrator complex GO:0032039 11 11 0,000 0,01188453 0,02453158 ! UV protection GO:0009650 11 11 0,000 0,01188453 0,02451741 ! L-glutamate transport GO:0015813 11 11 0,000 0,01188453 0,02450326 GO:0015800|acidic amino acid transport, ! retinol binding GO:0019841 11 11 0,000 0,01188453 0,02448912 ! regulation of organ growth GO:0046620 12 11 0,000 0,01188453 0,024475 ! regulation of cytokine production during immune response GO:0002718 11 11 0,000 0,01188453 0,02446089 ! regulation of T cell mediated immunity GO:0002709 15 11 0,000 0,01188453 0,0244468 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 11 11 0,000 0,01188453 0,02443272 ! regulation of interleukin-8 production GO:0032677 12 11 0,000 0,01188453 0,02441867 ! histone acetylation GO:0016573 11 11 0,000 0,01188453 0,02440462 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 12 11 0,000 0,01188453 0,0243906 ! delayed rectifier potassium channel activity GO:0005251 11 11 0,000 0,01188453 0,02437659 ! organic cation transmembrane transporter activity GO:0015101 11 11 0,000 0,01188453 0,0243626 ! chromatin silencing GO:0006342 11 11 0,000 0,01188453 0,02434862 ! gland morphogenesis GO:0022612 12 11 0,000 0,01188453 0,02433466 ! sulfate transmembrane transporter activity GO:0015116 11 11 0,000 0,01188453 0,02432071 ! hexose transmembrane transporter activity GO:0015149 11 11 0,000 0,01188453 0,02430678 ! icosanoid receptor activity GO:0004953 12 11 0,000 0,01188453 0,02429287 GO:0004954|prostanoid receptor activity, ! non-G-protein coupled 7TM receptor activity GO:0004926 12 11 0,000 0,01188453 0,02427897 ! negative regulation of neurological system process GO:0031645 12 11 0,000 0,01188453 0,02426509 ! acid secretion GO:0046717 11 11 0,000 0,01188453 0,02425122 ! nitric oxide mediated signal transduction GO:0007263 11 11 0,000 0,01188453 0,02423737 ! thyroid hormone metabolic process GO:0042403 11 11 0,000 0,01188453 0,02422354 ! quinone cofactor metabolic process GO:0042375 12 11 0,000 0,01188453 0,02420972 ! insulin-like growth factor receptor binding GO:0005159 12 11 0,000 0,01188453 0,02419592 ! midbody GO:0030496 11 11 0,000 0,01188453 0,02418213 ! interferon-alpha/beta receptor binding GO:0005132 11 11 0,000 0,01188453 0,02416836 ! cAMP-dependent protein kinase complex GO:0005952 11 11 0,000 0,01188453 0,02415461 ! water channel activity GO:0015250 11 11 0,000 0,01188453 0,02414087 ! response to nicotine GO:0035094 11 11 0,000 0,01188453 0,02412714 ! response to cold GO:0009409 11 11 0,000 0,01188453 0,02411343 ! adenylate cyclase activity GO:0004016 11 11 0,000 0,01188453 0,02409974 ! 'de novo' protein folding GO:0006458 12 12 0,000 0,01295835 0,02626234 ! centriole GO:0005814 12 12 0,000 0,01295835 0,02624745 ! organellar large ribosomal subunit GO:0000315 13 12 0,000 0,01295835 0,02623257 GO:0005762|mitochondrial large ribosomal subunit, ! cadmium ion binding GO:0046870 13 12 0,000 0,01295835 0,02621771 ! folic acid and derivative biosynthetic process GO:0009396 12 12 0,000 0,01295835 0,02620286 ! bone remodeling GO:0046849 12 12 0,000 0,01295835 0,02618803 ! peroxisomal transport GO:0043574 12 12 0,000 0,01295835 0,02617322 ! retina development in camera-type eye GO:0060041 13 12 0,000 0,01295835 0,02615842 ! hair follicle morphogenesis GO:0031069 12 12 0,000 0,01295835 0,02614364 ! voltage-gated sodium channel complex GO:0001518 13 12 0,000 0,01295835 0,02612888 GO:0034706|sodium channel complex, ! regulation of excitatory postsynaptic membrane potential GO:0060079 14 12 0,000 0,01295835 0,02611414 ! hippocampus development GO:0021766 12 12 0,000 0,01295835 0,02609941 ! negative regulation of lipid metabolic process GO:0045833 13 12 0,000 0,01295835 0,0260847 ! T cell selection GO:0045058 16 12 0,000 0,01295835 0,02607 ! cation:cation antiporter activity GO:0015491 12 12 0,000 0,01295835 0,02605532 ! induction of apoptosis via death domain receptors GO:0008625 12 12 0,000 0,01295835 0,02604066 ! T-tubule GO:0030315 13 12 0,000 0,01295835 0,02602601 ! methionine metabolic process GO:0006555 13 12 0,000 0,01295835 0,02601138 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 14 12 0,000 0,01295835 0,02599677 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! peptide antigen binding GO:0042605 12 12 0,000 0,01295835 0,02598217 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 0,01295835 0,02596759 ! cell-cell junction assembly GO:0007043 12 12 0,000 0,01295835 0,02595303 ! fear response GO:0042596 12 12 0,000 0,01295835 0,02593848 ! negative regulation of mitotic cell cycle GO:0045930 13 12 0,000 0,01295835 0,02592395 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 0,01295835 0,02590944 ! copper ion homeostasis GO:0055070 13 12 0,000 0,01295835 0,02589494 ! lipoprotein receptor activity GO:0030228 12 12 0,000 0,01295835 0,02588045 ! axon cargo transport GO:0008088 12 12 0,000 0,01295835 0,02586599 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 13 12 0,000 0,01295835 0,02585154 ! transcription elongation factor complex GO:0008023 13 12 0,000 0,01295835 0,0258371 ! nuclear outer membrane GO:0005640 12 12 0,000 0,01295835 0,02582268 ! beta-tubulin binding GO:0048487 12 12 0,000 0,01295835 0,02580828 ! autonomic nervous system development GO:0048483 12 12 0,000 0,01295835 0,0257939 ! positive regulation of interleukin-1 secretion GO:0050716 12 12 0,000 0,01295835 0,02577953 GO:0050704|regulation of interleukin-1 secretion, ! exoribonuclease activity GO:0004532 12 12 0,000 0,01295835 0,02576517 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! cofactor transport GO:0051181 12 12 0,000 0,01295835 0,02575084 ! regulation of epidermis development GO:0045682 12 12 0,000 0,01295835 0,02573651 ! protein-chromophore linkage GO:0018298 12 12 0,000 0,01295835 0,02572221 ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 12 12 0,000 0,01295835 0,02570792 ! cell killing GO:0001906 12 12 0,000 0,01295835 0,02569364 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 12 0,000 0,01295835 0,02567938 ! lymphocyte homeostasis GO:0002260 14 12 0,000 0,01295835 0,02566514 ! regulation of fatty acid oxidation GO:0046320 13 12 0,000 0,01295835 0,02565092 ! detection of bacterium GO:0016045 13 12 0,000 0,01295835 0,0256367 ! positive regulation of neuron apoptosis GO:0043525 12 12 0,000 0,01295835 0,02562251 ! dystrophin-associated glycoprotein complex GO:0016010 14 12 0,000 0,01295835 0,02560833 ! internal side of plasma membrane GO:0009898 14 12 0,000 0,01295835 0,02559417 ! RNA 3'-end processing GO:0031123 12 12 0,000 0,01295835 0,02558002 ! developmental induction GO:0031128 13 12 0,000 0,01295835 0,02556588 GO:0045168|cell-cell signaling involved in cell fate specification, ! fibrillar collagen GO:0005583 13 12 0,000 0,01295835 0,02555177 ! positive regulation of calcium-mediated signaling GO:0050850 14 12 0,000 0,01295835 0,02553767 ! inner ear receptor cell differentiation GO:0060113 13 12 0,000 0,01295835 0,02552358 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 0,01295835 0,02550951 ! very-long-chain fatty acid metabolic process GO:0000038 12 12 0,000 0,01295835 0,02549546 ! negative regulation of cell projection organization GO:0031345 14 12 0,000 0,01295835 0,02548142 ! thyroid gland development GO:0030878 12 12 0,000 0,01295835 0,02546739 ! non-recombinational repair GO:0000726 12 12 0,000 0,01295835 0,02545338 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 12 12 0,000 0,01295835 0,02543939 ! lipid localization GO:0010876 12 12 0,000 0,01295835 0,02542541 GO:0019915|lipid storage, ! regulation of glycolysis GO:0006110 12 12 0,000 0,01295835 0,02541145 ! response to cAMP GO:0051591 12 12 0,000 0,01295835 0,0253975 ! negative regulation of transcription factor import into nucleus GO:0042992 12 12 0,000 0,01295835 0,02538357 ! T cell proliferation GO:0042098 17 12 0,000 0,01295835 0,02536966 ! negative regulation of protein amino acid phosphorylation GO:0001933 16 12 0,000 0,01295835 0,02535575 ! receptor signaling protein tyrosine kinase activity GO:0004716 13 12 0,000 0,01295835 0,02534187 ! two-component signal transduction system (phosphorelay) GO:0000160 13 12 0,000 0,01295835 0,025328 ! peptide or protein amino-terminal blocking GO:0018409 13 12 0,000 0,01295835 0,02531414 ! drug transport GO:0015893 12 12 0,000 0,01295835 0,0253003 ! GTP-dependent protein binding GO:0030742 12 12 0,000 0,01295835 0,02528648 ! regulation of interleukin-6 biosynthetic process GO:0045408 12 12 0,000 0,01295835 0,02527267 ! T cell receptor complex GO:0042101 12 12 0,000 0,01295835 0,02525887 ! membrane protein proteolysis GO:0033619 13 12 0,000 0,01295835 0,02524509 GO:0006509|membrane protein ectodomain proteolysis, ! protein disulfide oxidoreductase activity GO:0015035 12 12 0,000 0,01295835 0,02523133 ! histone acetyltransferase complex GO:0000123 13 12 0,000 0,01295835 0,02521758 ! dendritic spine GO:0043197 12 12 0,000 0,01295835 0,02520384 ! ATP-binding cassette (ABC) transporter complex GO:0043190 12 12 0,000 0,01295835 0,02519012 ! alpha-beta T cell activation GO:0046631 13 12 0,000 0,01295835 0,02517642 ! organic anion transmembrane transporter activity GO:0008514 13 12 0,000 0,01295835 0,02516273 ! vasoconstriction GO:0042310 13 12 0,000 0,01295835 0,02514905 ! DNA unwinding during replication GO:0006268 12 12 0,000 0,01295835 0,02513539 ! cellular amino acid derivative catabolic process GO:0042219 16 12 0,000 0,01295835 0,02512174 ! mRNA splice site selection GO:0006376 13 12 0,000 0,01295835 0,02510811 ! phosphate transmembrane transporter activity GO:0015114 13 12 0,000 0,01295835 0,0250945 ! trans-Golgi network transport vesicle membrane GO:0012510 15 12 0,000 0,01295835 0,0250809 ! ubiquitin protein ligase binding GO:0031625 12 12 0,000 0,01295835 0,02506731 ! monosaccharide transmembrane transporter activity GO:0015145 12 12 0,000 0,01295835 0,02505374 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 12 12 0,000 0,01295835 0,02504018 ! hexosaminidase activity GO:0015929 12 12 0,000 0,01295835 0,02502664 ! diacylglycerol kinase activity GO:0004143 13 12 0,000 0,01295835 0,02501311 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 0,01295835 0,0249996 ! activation of NF-kappaB-inducing kinase activity GO:0007250 12 12 0,000 0,01295835 0,0249861 ! protein kinase C binding GO:0005080 13 12 0,000 0,01295835 0,02497261 ! catecholamine biosynthetic process GO:0042423 13 12 0,000 0,01295835 0,02495914 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 15 12 0,000 0,01295835 0,02494569 ! establishment or maintenance of apical/basal cell polarity GO:0035088 12 12 0,000 0,01295835 0,02493225 ! L-fucose metabolic process GO:0042354 14 12 0,000 0,01295835 0,02491882 ! acylglycerol O-acyltransferase activity GO:0016411 12 12 0,000 0,01295835 0,02490541 ! C-acyltransferase activity GO:0016408 12 12 0,000 0,01295835 0,02489201 ! steroid hydroxylase activity GO:0008395 12 12 0,000 0,01295835 0,02487863 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01295835 0,02486526 ! calcium-activated potassium channel activity GO:0015269 14 12 0,000 0,01295835 0,02485191 ! SWI/SNF-type complex GO:0070603 13 12 0,000 0,01295835 0,02483857 GO:0016514|SWI/SNF complex, ! cilium part GO:0044441 12 12 0,000 0,01295835 0,02482524 ! positive regulation of translation GO:0045727 13 13 0,000 0,01403107 0,02686593 ! ER-associated protein catabolic process GO:0030433 13 13 0,000 0,01403107 0,02685153 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01403107 0,02683715 ! superoxide anion generation GO:0042554 13 13 0,000 0,01403107 0,02682278 ! pteridine and derivative biosynthetic process GO:0042559 14 13 0,000 0,01403107 0,02680843 ! cis-Golgi network GO:0005801 14 13 0,000 0,01403107 0,02679409 ! regulation of chemokine production GO:0032642 13 13 0,000 0,01403107 0,02677977 ! phospholipid catabolic process GO:0009395 14 13 0,000 0,01403107 0,02676547 ! endothelial cell migration GO:0043542 13 13 0,000 0,01403107 0,02675118 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 13 13 0,000 0,01403107 0,0267369 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01403107 0,02672264 ! cartilage condensation GO:0001502 14 13 0,000 0,01403107 0,0267084 ! organelle fusion GO:0048284 14 13 0,000 0,01403107 0,02669417 ! positive regulation of lipid metabolic process GO:0045834 13 13 0,000 0,01403107 0,02667995 ! pseudouridine synthesis GO:0001522 14 13 0,000 0,01403107 0,02666576 ! negative regulation of gene expression, epigenetic GO:0045814 13 13 0,000 0,01403107 0,02665157 ! regulation of interleukin-2 biosynthetic process GO:0045076 13 13 0,000 0,01403107 0,0266374 ! negative regulation of proteolysis GO:0045861 13 13 0,000 0,01403107 0,02662325 ! regulation of mRNA processing GO:0050684 13 13 0,000 0,01403107 0,02660911 ! arginine metabolic process GO:0006525 13 13 0,000 0,01403107 0,02659499 ! WW domain binding GO:0050699 14 13 0,000 0,01403107 0,02658088 ! cholesterol binding GO:0015485 13 13 0,000 0,01403107 0,02656678 ! negative regulation of microtubule depolymerization GO:0007026 15 13 0,000 0,01403107 0,02655271 GO:0031114|regulation of microtubule depolymerization, ! Golgi organization GO:0007030 16 13 0,000 0,01403107 0,02653864 ! negative regulation of endothelial cell migration GO:0010596 13 13 0,000 0,01403107 0,02652459 ! integral to peroxisomal membrane GO:0005779 13 13 0,000 0,01403107 0,02651056 GO:0031231|intrinsic to peroxisomal membrane, ! integral to membrane of membrane fraction GO:0000299 14 13 0,000 0,01403107 0,02649654 ! regulation of heart rate GO:0002027 14 13 0,000 0,01403107 0,02648253 ! positive regulation of carbohydrate metabolic process GO:0045913 14 13 0,000 0,01403107 0,02646854 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 14 13 0,000 0,01403107 0,02645457 ! negative regulation of immune response GO:0050777 17 13 0,000 0,01403107 0,02644061 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 13 0,000 0,01403107 0,02642666 ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01403107 0,02641273 ! response to estradiol stimulus GO:0032355 14 13 0,000 0,01403107 0,02639882 ! anaphase-promoting complex GO:0005680 13 13 0,000 0,01403107 0,02638492 ! nucleotide diphosphatase activity GO:0004551 13 13 0,000 0,01403107 0,02637103 ! NADP metabolic process GO:0006739 13 13 0,000 0,01403107 0,02635716 ! regulation of erythrocyte differentiation GO:0045646 13 13 0,000 0,01403107 0,0263433 ! intestinal absorption GO:0050892 13 13 0,000 0,01403107 0,02632946 ! eukaryotic cell surface binding GO:0043499 14 13 0,000 0,01403107 0,02631563 ! digestive tract morphogenesis GO:0048546 13 13 0,000 0,01403107 0,02630181 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 14 13 0,000 0,01403107 0,02628801 ! regulation of cellular carbohydrate catabolic process GO:0043471 14 13 0,000 0,01403107 0,02627423 GO:0043470|regulation of carbohydrate catabolic process, ! tropomyosin binding GO:0005523 13 13 0,000 0,01403107 0,02626046 ! carbon-sulfur lyase activity GO:0016846 13 13 0,000 0,01403107 0,0262467 ! embryonic placenta development GO:0001892 13 13 0,000 0,01403107 0,02623296 ! positive regulation of protein polymerization GO:0032273 13 13 0,000 0,01403107 0,02621923 ! insulin secretion GO:0030073 13 13 0,000 0,01403107 0,02620552 ! positive regulation of cellular catabolic process GO:0031331 14 13 0,000 0,01403107 0,02619182 ! G1 phase of mitotic cell cycle GO:0000080 13 13 0,000 0,01403107 0,02617814 ! replisome GO:0030894 14 13 0,000 0,01403107 0,02616447 GO:0043601|nuclear replisome, ! regulation of nitric-oxide synthase activity GO:0050999 13 13 0,000 0,01403107 0,02615081 ! double-strand break repair via homologous recombination GO:0000724 13 13 0,000 0,01403107 0,02613717 GO:0000725|recombinational repair, ! copper ion transport GO:0006825 13 13 0,000 0,01403107 0,02612354 ! regulation of cell-cell adhesion GO:0022407 13 13 0,000 0,01403107 0,02610993 ! forelimb morphogenesis GO:0035136 13 13 0,000 0,01403107 0,02609633 ! mating GO:0007618 13 13 0,000 0,01403107 0,02608275 ! phosphatidylinositol phosphate kinase activity GO:0016307 14 13 0,000 0,01403107 0,02606918 ! MAP kinase activity GO:0004707 14 13 0,000 0,01403107 0,02605562 ! cytokine biosynthetic process GO:0042089 13 13 0,000 0,01403107 0,02604208 ! ventral spinal cord development GO:0021517 13 13 0,000 0,01403107 0,02602855 ! prenyltransferase activity GO:0004659 14 13 0,000 0,01403107 0,02601503 ! platelet-derived growth factor receptor signaling pathway GO:0048008 15 13 0,000 0,01403107 0,02600153 ! regulation of skeletal muscle fiber development GO:0048742 13 13 0,000 0,01403107 0,02598805 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 15 13 0,000 0,01403107 0,02597457 ! protein kinase C activity GO:0004697 15 13 0,000 0,01403107 0,02596112 ! oligodendrocyte differentiation GO:0048709 13 13 0,000 0,01403107 0,02594767 ! water transporter activity GO:0005372 13 13 0,000 0,01403107 0,02593424 ! exocrine system development GO:0035272 14 13 0,000 0,01403107 0,02592082 ! dicarboxylic acid transmembrane transporter activity GO:0005310 13 13 0,000 0,01403107 0,02590742 ! monoamine transport GO:0015844 13 13 0,000 0,01403107 0,02589403 ! CoA hydrolase activity GO:0016289 13 13 0,000 0,01403107 0,02588066 ! embryo implantation GO:0007566 13 13 0,000 0,01403107 0,0258673 ! G1/S transition checkpoint GO:0031575 13 13 0,000 0,01403107 0,02585395 ! positive regulation of alpha-beta T cell differentiation GO:0046638 13 13 0,000 0,01403107 0,02584062 ! immunoglobulin binding GO:0019865 13 13 0,000 0,01403107 0,0258273 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,01403107 0,02581399 ! anchored to plasma membrane GO:0046658 14 13 0,000 0,01403107 0,0258007 ! MHC class I protein binding GO:0042288 13 13 0,000 0,01403107 0,02578742 ! histone deacetylation GO:0016575 13 13 0,000 0,01403107 0,02577415 ! calcium channel regulator activity GO:0005246 14 13 0,000 0,01403107 0,0257609 ! neuroblast proliferation GO:0007405 13 13 0,000 0,01403107 0,02574766 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01403107 0,02573444 ! response to gamma radiation GO:0010332 13 13 0,000 0,01403107 0,02572123 ! sarcomere organization GO:0045214 13 13 0,000 0,01403107 0,02570803 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 15 13 0,000 0,01403107 0,02569485 ! cAMP binding GO:0030552 13 13 0,000 0,01403107 0,02568168 ! fucosyltransferase activity GO:0008417 14 13 0,000 0,01403107 0,02566852 ! cilium assembly GO:0042384 13 13 0,000 0,01403107 0,02565538 ! negative regulation of leukocyte proliferation GO:0070664 13 13 0,000 0,01403107 0,02564225 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! bacterial binding GO:0008367 13 13 0,000 0,01403107 0,02562913 ! regulation of NF-kappaB import into nucleus GO:0042345 13 13 0,000 0,01403107 0,02561603 ! acrosome reaction GO:0007340 13 13 0,000 0,01403107 0,02560294 ! microtubule-based flagellum GO:0009434 13 13 0,000 0,01403107 0,02558986 ! nucleolar part GO:0044452 13 13 0,000 0,01403107 0,0255768 ! axoneme part GO:0044447 13 13 0,000 0,01403107 0,02556375 ! tRNA modification GO:0006400 14 14 0,000 0,0151027 0,02750217 ! positive regulation of blood pressure GO:0045777 15 14 0,000 0,0151027 0,02748815 ! transferase activity, transferring amino-acyl groups GO:0016755 14 14 0,000 0,0151027 0,02747415 ! negative regulation of bone remodeling GO:0046851 14 14 0,000 0,0151027 0,02746016 ! 2'-deoxyribonucleotide metabolic process GO:0009394 15 14 0,000 0,0151027 0,02744619 GO:0019692|deoxyribose phosphate metabolic process, ! transcription from RNA polymerase III promoter GO:0006383 14 14 0,000 0,0151027 0,02743223 ! guanylate kinase activity GO:0004385 16 14 0,000 0,0151027 0,02741828 ! striated muscle thin filament GO:0005865 15 14 0,000 0,0151027 0,02740435 ! patterning of blood vessels GO:0001569 14 14 0,000 0,0151027 0,02739043 ! mechanoreceptor differentiation GO:0042490 15 14 0,000 0,0151027 0,02737653 ! palate development GO:0060021 15 14 0,000 0,0151027 0,02736264 ! centrosome cycle GO:0007098 14 14 0,000 0,0151027 0,02734876 ! regulation of defense response to virus GO:0050688 14 14 0,000 0,0151027 0,0273349 ! cAMP-dependent protein kinase regulator activity GO:0008603 14 14 0,000 0,0151027 0,02732105 ! ephrin receptor activity GO:0005003 16 14 0,000 0,0151027 0,02730722 ! protein polyubiquitination GO:0000209 15 14 0,000 0,0151027 0,0272934 ! glycine metabolic process GO:0006544 15 14 0,000 0,0151027 0,02727959 ! plasma membrane organization GO:0007009 14 14 0,000 0,0151027 0,0272658 ! tyrosine metabolic process GO:0006570 16 14 0,000 0,0151027 0,02725202 ! response to retinoic acid GO:0032526 14 14 0,000 0,0151027 0,02723826 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 16 14 0,000 0,0151027 0,02722451 ! lysosomal transport GO:0007041 14 14 0,000 0,0151027 0,02721077 ! rough endoplasmic reticulum GO:0005791 14 14 0,000 0,0151027 0,02719705 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 14 14 0,000 0,0151027 0,02718334 ! regulation of the force of heart contraction GO:0002026 15 14 0,000 0,0151027 0,02716965 ! bone mineralization GO:0030282 14 14 0,000 0,0151027 0,02715597 ! protein kinase activator activity GO:0030295 14 14 0,000 0,0151027 0,0271423 ! NLS-bearing substrate import into nucleus GO:0006607 15 14 0,000 0,0151027 0,02712865 ! cerebellum development GO:0021549 15 14 0,000 0,0151027 0,02711501 ! G1 phase GO:0051318 14 14 0,000 0,0151027 0,02710138 ! negative regulation of blood coagulation GO:0030195 16 14 0,000 0,0151027 0,02708777 ! negative regulation of protein secretion GO:0050709 14 14 0,000 0,0151027 0,02707417 ! water homeostasis GO:0030104 14 14 0,000 0,0151027 0,02706059 ! peptide hormone binding GO:0017046 14 14 0,000 0,0151027 0,02704702 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,0151027 0,02703346 ! glutamine family amino acid biosynthetic process GO:0009084 15 14 0,000 0,0151027 0,02701992 ! regulation of ATPase activity GO:0043462 15 14 0,000 0,0151027 0,02700639 ! racemase and epimerase activity GO:0016854 14 14 0,000 0,0151027 0,02699287 ! regulation of leukocyte mediated cytotoxicity GO:0001910 18 14 0,000 0,0151027 0,02697937 ! positive regulation of calcium ion transport GO:0051928 17 14 0,000 0,0151027 0,02696588 ! regulation of blood vessel endothelial cell migration GO:0043535 14 14 0,000 0,0151027 0,0269524 ! regulation of calcium-mediated signaling GO:0050848 16 14 0,000 0,0151027 0,02693894 ! positive regulation of synaptic transmission GO:0050806 14 14 0,000 0,0151027 0,02692549 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 16 14 0,000 0,0151027 0,02691205 ! lactation GO:0007595 15 14 0,000 0,0151027 0,02689863 ! reproductive cellular process GO:0048610 14 14 0,000 0,0151027 0,02688522 ! positive regulation of cell killing GO:0031343 18 14 0,000 0,0151027 0,02687183 ! sulfur amino acid biosynthetic process GO:0000097 15 14 0,000 0,0151027 0,02685844 ! dicarboxylic acid transport GO:0006835 14 14 0,000 0,0151027 0,02684507 ! inorganic anion exchanger activity GO:0005452 15 14 0,000 0,0151027 0,02683172 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 15 14 0,000 0,0151027 0,02681838 ! negative regulation of cytokine biosynthetic process GO:0042036 14 14 0,000 0,0151027 0,02680505 ! negative regulation of ion transport GO:0043271 14 14 0,000 0,0151027 0,02679173 ! retinoic acid receptor binding GO:0042974 14 14 0,000 0,0151027 0,02677843 ! startle response GO:0001964 14 14 0,000 0,0151027 0,02676514 ! 2 iron, 2 sulfur cluster binding GO:0051537 14 14 0,000 0,0151027 0,02675186 ! activation of MAPKK activity GO:0000186 15 14 0,000 0,0151027 0,0267386 ! response to hexose stimulus GO:0009746 14 14 0,000 0,0151027 0,02672535 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! cytokine metabolic process GO:0042107 14 14 0,000 0,0151027 0,02671211 ! organic alcohol transport GO:0015850 15 14 0,000 0,0151027 0,02669889 ! preassembly of GPI anchor in ER membrane GO:0016254 15 14 0,000 0,0151027 0,02668568 ! eukaryotic translation initiation factor 4F complex GO:0016281 14 14 0,000 0,0151027 0,02667248 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,0151027 0,0266593 ! L-amino acid transport GO:0015807 14 14 0,000 0,0151027 0,02664612 ! microfilament motor activity GO:0000146 14 14 0,000 0,0151027 0,02663297 ! stem cell development GO:0048864 14 14 0,000 0,0151027 0,02661982 GO:0019827|stem cell maintenance, ! positive regulation of protein import into nucleus GO:0042307 15 14 0,000 0,0151027 0,02660669 ! DNA replication initiation GO:0006270 14 14 0,000 0,0151027 0,02659357 ! T cell differentiation in the thymus GO:0033077 18 14 0,000 0,0151027 0,02658046 ! regulation of cellular pH GO:0030641 14 14 0,000 0,0151027 0,02656737 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,0151027 0,02655429 ! calcium activated cation channel activity GO:0005227 16 14 0,000 0,0151027 0,02654122 ! sulfuric ester hydrolase activity GO:0008484 15 14 0,000 0,0151027 0,02652816 ! serotonin receptor activity GO:0004993 14 14 0,000 0,0151027 0,02651512 ! positive regulation of bone mineralization GO:0030501 15 14 0,000 0,0151027 0,02650209 ! synaptic transmission, cholinergic GO:0007271 15 14 0,000 0,0151027 0,02648907 ! dopamine metabolic process GO:0042417 17 14 0,000 0,0151027 0,02647607 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,0151027 0,02646308 ! ion gated channel activity GO:0022839 16 14 0,000 0,0151027 0,0264501 ! male genitalia development GO:0030539 14 14 0,000 0,0151027 0,02643713 ! regulation of axon extension GO:0030516 15 14 0,000 0,0151027 0,02642418 ! regulation of BMP signaling pathway GO:0030510 14 14 0,000 0,0151027 0,02641124 ! estrogen receptor signaling pathway GO:0030520 14 14 0,000 0,0151027 0,02639831 ! interleukin-1 receptor binding GO:0005149 14 14 0,000 0,0151027 0,0263854 ! defense response to virus GO:0051607 19 14 0,000 0,0151027 0,0263725 ! cadherin binding GO:0045296 16 14 0,000 0,0151027 0,02635961 ! negative regulation of hormone secretion GO:0046888 16 15 0,000 0,01617324 0,02821429 ! nuclear replication fork GO:0043596 16 15 0,000 0,01617324 0,02820052 ! phosphoinositide phosphorylation GO:0046854 16 15 0,000 0,01617324 0,02818675 GO:0046834|lipid phosphorylation, ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,01617324 0,028173 ! cardiac muscle contraction GO:0060048 16 15 0,000 0,01617324 0,02815927 ! polysome GO:0005844 16 15 0,000 0,01617324 0,02814554 ! mitotic chromosome condensation GO:0007076 15 15 0,000 0,01617324 0,02813183 ! regulation of viral genome replication GO:0045069 15 15 0,000 0,01617324 0,02811814 ! regulation of survival gene product expression GO:0045884 15 15 0,000 0,01617324 0,02810445 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 15 0,000 0,01617324 0,02809079 ! glycoprotein catabolic process GO:0006516 15 15 0,000 0,01617324 0,02807713 ! DNA duplex unwinding GO:0032508 15 15 0,000 0,01617324 0,02806349 GO:0032392|DNA geometric change, ! glutamine metabolic process GO:0006541 16 15 0,000 0,01617324 0,02804986 ! proton-transporting V-type ATPase complex GO:0033176 15 15 0,000 0,01617324 0,02803624 ! response to vitamin A GO:0033189 15 15 0,000 0,01617324 0,02802264 ! protease binding GO:0002020 16 15 0,000 0,01617324 0,02800905 ! regulation of ion transmembrane transporter activity GO:0032412 15 15 0,000 0,01617324 0,02799547 ! actin filament bundle formation GO:0051017 15 15 0,000 0,01617324 0,02798191 ! calcium ion-dependent exocytosis GO:0017156 15 15 0,000 0,01617324 0,02796836 ! purine nucleoside monophosphate metabolic process GO:0009126 16 15 0,000 0,01617324 0,02795482 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,01617324 0,02794129 ! positive regulation of biomineral formation GO:0070169 16 15 0,000 0,01617324 0,02792778 ! positive regulation of oxidoreductase activity GO:0051353 15 15 0,000 0,01617324 0,02791428 ! filopodium GO:0030175 15 15 0,000 0,01617324 0,0279008 ! negative regulation of inflammatory response GO:0050728 15 15 0,000 0,01617324 0,02788733 ! positive regulation of transmission of nerve impulse GO:0051971 15 15 0,000 0,01617324 0,02787387 ! branched chain family amino acid metabolic process GO:0009081 15 15 0,000 0,01617324 0,02786042 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01617324 0,02784699 ! heme biosynthetic process GO:0006783 15 15 0,000 0,01617324 0,02783357 ! SMAD binding GO:0046332 16 15 0,000 0,01617324 0,02782016 ! nerve development GO:0021675 16 15 0,000 0,01617324 0,02780677 ! epithelial to mesenchymal transition GO:0001837 16 15 0,000 0,01617324 0,02779339 ! mannose binding GO:0005537 15 15 0,000 0,01617324 0,02778002 ! phosphoprotein binding GO:0051219 17 15 0,000 0,01617324 0,02776666 ! mismatched DNA binding GO:0030983 15 15 0,000 0,01617324 0,02775332 ! antigen receptor-mediated signaling pathway GO:0050851 21 15 0,000 0,01617324 0,02773999 ! regulation of skeletal muscle tissue development GO:0048641 15 15 0,000 0,01617324 0,02772667 ! synaptonemal complex GO:0000795 15 15 0,000 0,01617324 0,02771337 ! N-terminal protein amino acid modification GO:0031365 16 15 0,000 0,01617324 0,02770007 ! positive regulation of protein complex assembly GO:0031334 15 15 0,000 0,01617324 0,0276868 ! water transport GO:0006833 15 15 0,000 0,01617324 0,02767353 GO:0042044|fluid transport, ! phosphatidylinositol metabolic process GO:0046488 16 15 0,000 0,01617324 0,02766028 ! viral genome replication GO:0019079 15 15 0,000 0,01617324 0,02764703 ! phosphatidylcholine metabolic process GO:0046470 17 15 0,000 0,01617324 0,02763381 ! inositol metabolic process GO:0006020 15 15 0,000 0,01617324 0,02762059 ! sulfate transport GO:0008272 15 15 0,000 0,01617324 0,02760739 ! protein-lipid complex GO:0032994 15 15 0,000 0,01617324 0,0275942 GO:0034358|plasma lipoprotein particle, ! positive regulation of ion transport GO:0043270 18 15 0,000 0,01617324 0,02758102 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 15 15 0,000 0,01617324 0,02756785 ! heart looping GO:0001947 15 15 0,000 0,01617324 0,0275547 ! isoprenoid biosynthetic process GO:0008299 16 15 0,000 0,01617324 0,02754156 ! protein histidine kinase activity GO:0004673 16 15 0,000 0,01617324 0,02752843 GO:0000155|two-component sensor activity, ! cardiac muscle tissue development GO:0048738 15 15 0,000 0,01617324 0,02751532 ! regulation of striated muscle contraction GO:0006942 16 15 0,000 0,01617324 0,02750222 ! response to osmotic stress GO:0006970 16 15 0,000 0,01617324 0,02748913 ! fructose metabolic process GO:0006000 15 15 0,000 0,01617324 0,02747605 ! ubiquitin binding GO:0043130 15 15 0,000 0,01617324 0,02746298 ! vesicle coating GO:0006901 16 15 0,000 0,01617324 0,02744993 ! DNA integration GO:0015074 16 15 0,000 0,01617324 0,02743689 ! alcohol binding GO:0043178 16 15 0,000 0,01617324 0,02742386 ! disulfide oxidoreductase activity GO:0015036 15 15 0,000 0,01617324 0,02741085 ! intermediate filament cytoskeleton organization GO:0045104 16 15 0,000 0,01617324 0,02739784 ! regulation of vasodilation GO:0042312 15 15 0,000 0,01617324 0,02738485 ! genitalia development GO:0048806 15 15 0,000 0,01617324 0,02737187 ! structural constituent of eye lens GO:0005212 15 15 0,000 0,01617324 0,02735891 ! regulation of monooxygenase activity GO:0032768 15 15 0,000 0,01617324 0,02734595 ! voltage-gated sodium channel activity GO:0005248 17 15 0,000 0,01617324 0,02733301 ! ribonucleoprotein binding GO:0043021 16 15 0,000 0,01617324 0,02732008 ! proton-transporting ATP synthase complex GO:0045259 15 15 0,000 0,01617324 0,02730717 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 15 15 0,000 0,01617324 0,02729426 ! regulation of immunoglobulin production GO:0002637 19 15 0,000 0,01617324 0,02728137 ! retinoic acid receptor activity GO:0003708 15 15 0,000 0,01617324 0,02726849 ! receptor activator activity GO:0030546 15 15 0,000 0,01617324 0,02725562 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 15 15 0,000 0,01617324 0,02724276 ! protein transmembrane transporter activity GO:0008320 15 15 0,000 0,01617324 0,02722992 ! phosphoinositide 3-kinase activity GO:0035004 16 15 0,000 0,01617324 0,02721709 ! sialyltransferase activity GO:0008373 15 15 0,000 0,01617324 0,02720427 ! platelet-derived growth factor receptor binding GO:0005161 16 15 0,000 0,01617324 0,02719146 ! drug transporter activity GO:0015238 15 15 0,000 0,01617324 0,02717866 ! negative regulation of homeostatic process GO:0032845 15 15 0,000 0,01617324 0,02716588 ! phosphoinositide 3-kinase complex GO:0005942 16 15 0,000 0,01617324 0,02715311 ! binding of sperm to zona pellucida GO:0007339 16 15 0,000 0,01617324 0,02714035 ! peptide hormone processing GO:0016486 17 15 0,000 0,01617324 0,0271276 ! aldo-keto reductase activity GO:0004033 15 15 0,000 0,01617324 0,02711486 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,01617324 0,02710214 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 16 16 0,000 0,01724269 0,0288807 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,01724269 0,02886716 ! positive regulation of hormone secretion GO:0046887 17 16 0,000 0,01724269 0,02885364 ! protein amino acid ADP-ribosylation GO:0006471 18 16 0,000 0,01724269 0,02884012 ! response to vitamin GO:0033273 16 16 0,000 0,01724269 0,02882662 ! regulation of postsynaptic membrane potential GO:0060078 18 16 0,000 0,01724269 0,02881313 ! kinesin complex GO:0005871 16 16 0,000 0,01724269 0,02879965 ! cornified envelope GO:0001533 18 16 0,000 0,01724269 0,02878619 ! regulation of transmembrane transporter activity GO:0022898 16 16 0,000 0,01724269 0,02877274 GO:0032409|regulation of transporter activity, ! negative regulation of epithelial cell proliferation GO:0050680 17 16 0,000 0,01724269 0,0287593 ! pyrimidine ribonucleotide metabolic process GO:0009218 18 16 0,000 0,01724269 0,02874587 ! pituitary gland development GO:0021983 16 16 0,000 0,01724269 0,02873246 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 18 16 0,000 0,01724269 0,02871906 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 19 16 0,000 0,01724269 0,02870567 ! cell-substrate junction assembly GO:0007044 18 16 0,000 0,01724269 0,02869229 ! peptidyl-serine phosphorylation GO:0018105 16 16 0,000 0,01724269 0,02867893 ! branching involved in ureteric bud morphogenesis GO:0001658 16 16 0,000 0,01724269 0,02866558 GO:0060675|ureteric bud morphogenesis, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 16 16 0,000 0,01724269 0,02865224 ! nucleobase metabolic process GO:0009112 19 16 0,000 0,01724269 0,02863891 ! beta-catenin binding GO:0008013 17 16 0,000 0,01724269 0,0286256 ! regulation of steroid metabolic process GO:0019218 17 16 0,000 0,01724269 0,0286123 ! neuron recognition GO:0008038 17 16 0,000 0,01724269 0,02859901 ! oogenesis GO:0048477 19 16 0,000 0,01724269 0,02858573 ! low-density lipoprotein binding GO:0030169 17 16 0,000 0,01724269 0,02857246 ! clathrin vesicle coat GO:0030125 19 16 0,000 0,01724269 0,02855921 ! COPI-coated vesicle GO:0030137 16 16 0,000 0,01724269 0,02854597 ! sphingolipid biosynthetic process GO:0030148 16 16 0,000 0,01724269 0,02853274 ! biomineral formation GO:0031214 16 16 0,000 0,01724269 0,02851953 ! vitamin transport GO:0051180 16 16 0,000 0,01724269 0,02850632 ! folic acid and derivative metabolic process GO:0006760 16 16 0,000 0,01724269 0,02849313 ! organic cation transport GO:0015695 16 16 0,000 0,01724269 0,02847995 ! proximal/distal pattern formation GO:0009954 16 16 0,000 0,01724269 0,02846679 ! regulation of glucose import GO:0046324 17 16 0,000 0,01724269 0,02845363 GO:0010827|regulation of glucose transport, ! aromatic compound biosynthetic process GO:0019438 17 16 0,000 0,01724269 0,02844049 ! aromatic compound catabolic process GO:0019439 18 16 0,000 0,01724269 0,02842736 ! negative regulation of coagulation GO:0050819 18 16 0,000 0,01724269 0,02841424 ! tRNA binding GO:0000049 16 16 0,000 0,01724269 0,02840113 ! regulation of cell killing GO:0031341 20 16 0,000 0,01724269 0,02838804 ! negative regulation of defense response GO:0031348 16 16 0,000 0,01724269 0,02837496 ! regulation of neuronal synaptic plasticity GO:0048168 16 16 0,000 0,01724269 0,02836189 ! hindlimb morphogenesis GO:0035137 16 16 0,000 0,01724269 0,02834883 ! bile acid metabolic process GO:0008206 16 16 0,000 0,01724269 0,02833578 ! axis specification GO:0009798 16 16 0,000 0,01724269 0,02832275 ! adult walking behavior GO:0007628 17 16 0,000 0,01724269 0,02830973 ! C-C chemokine binding GO:0019957 16 16 0,000 0,01724269 0,02829672 GO:0016493|C-C chemokine receptor activity, ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 18 16 0,000 0,01724269 0,02828372 ! protein phosphatase binding GO:0019903 17 16 0,000 0,01724269 0,02827073 ! epidermis morphogenesis GO:0048730 16 16 0,000 0,01724269 0,02825776 ! acyl-CoA dehydrogenase activity GO:0003995 16 16 0,000 0,01724269 0,0282448 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01724269 0,02823185 ! SH2 domain binding GO:0042169 19 16 0,000 0,01724269 0,02821891 ! UDP-galactosyltransferase activity GO:0035250 17 16 0,000 0,01724269 0,02820598 ! RNA methyltransferase activity GO:0008173 16 16 0,000 0,01724269 0,02819307 ! neutral amino acid transport GO:0015804 16 16 0,000 0,01724269 0,02818016 ! glucuronosyltransferase activity GO:0015020 17 16 0,000 0,01724269 0,02816727 ! regulation of alpha-beta T cell differentiation GO:0046637 16 16 0,000 0,01724269 0,02815439 ! cellular pigmentation GO:0033059 16 16 0,000 0,01724269 0,02814153 ! mannosidase activity GO:0015923 19 16 0,000 0,01724269 0,02812867 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 16 16 0,000 0,01724269 0,02811583 ! negative regulation of tissue remodeling GO:0034104 16 16 0,000 0,01724269 0,02810299 ! positive regulation of neurological system process GO:0031646 16 16 0,000 0,01724269 0,02809017 ! neuromuscular synaptic transmission GO:0007274 16 16 0,000 0,01724269 0,02807736 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,01724269 0,02806457 ! sperm-egg recognition GO:0035036 17 16 0,000 0,01724269 0,02805178 ! axoneme GO:0005930 16 16 0,000 0,01724269 0,02803901 ! anion exchanger activity GO:0015380 18 17 0,000 0,01831105 0,02976275 ! neuron maturation GO:0042551 18 17 0,000 0,01831105 0,02974921 ! metencephalon development GO:0022037 18 17 0,000 0,01831105 0,02973569 ! regulation of lipid biosynthetic process GO:0046890 18 17 0,000 0,01831105 0,02972217 ! reciprocal meiotic recombination GO:0007131 17 17 0,000 0,01831105 0,02970866 ! hemoglobin complex GO:0005833 18 17 0,000 0,01831105 0,02969517 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 17 17 0,000 0,01831105 0,02968169 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 17 17 0,000 0,01831105 0,02966823 ! protein amino acid deacetylation GO:0006476 17 17 0,000 0,01831105 0,02965477 ! protein amino acid acetylation GO:0006473 19 17 0,000 0,01831105 0,02964133 ! positive regulation of nucleocytoplasmic transport GO:0046824 18 17 0,000 0,01831105 0,0296279 ! regulation of neurotransmitter secretion GO:0046928 18 17 0,000 0,01831105 0,02961448 ! striated muscle thick filament GO:0005863 19 17 0,000 0,01831105 0,02960107 GO:0032982|myosin filament, ! gamma-aminobutyric acid signaling pathway GO:0007214 17 17 0,000 0,01831105 0,02958768 ! glial cell development GO:0021782 17 17 0,000 0,01831105 0,0295743 ! regulation of muscle cell differentiation GO:0051147 17 17 0,000 0,01831105 0,02956093 ! pancreas development GO:0031016 17 17 0,000 0,01831105 0,02954757 ! acetylcholine receptor activity GO:0015464 17 17 0,000 0,01831105 0,02953422 ! nuclear heterochromatin GO:0005720 18 17 0,000 0,01831105 0,02952089 ! calcium-dependent protein binding GO:0048306 19 17 0,000 0,01831105 0,02950757 ! cerebral cortex development GO:0021987 17 17 0,000 0,01831105 0,02949426 ! cellular response to starvation GO:0009267 18 17 0,000 0,01831105 0,02948096 ! signal sequence binding GO:0005048 17 17 0,000 0,01831105 0,02946768 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 17 17 0,000 0,01831105 0,0294544 ! cellular macromolecular complex disassembly GO:0034623 18 17 0,000 0,01831105 0,02944114 ! transforming growth factor beta receptor activity GO:0005024 17 17 0,000 0,01831105 0,02942789 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,01831105 0,02941465 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 17 17 0,000 0,01831105 0,02940143 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 17 0,000 0,01831105 0,02938821 ! actin filament bundle GO:0032432 17 17 0,000 0,01831105 0,02937501 GO:0001725|stress fiber, ! small nucleolar ribonucleoprotein complex GO:0005732 17 17 0,000 0,01831105 0,02936182 ! response to lipopolysaccharide GO:0032496 17 17 0,000 0,01831105 0,02934864 ! plasma membrane fusion GO:0045026 18 17 0,000 0,01831105 0,02933547 ! regulation of protein binding GO:0043393 18 17 0,000 0,01831105 0,02932232 ! recycling endosome GO:0055037 18 17 0,000 0,01831105 0,02930918 ! prostaglandin metabolic process GO:0006693 18 17 0,000 0,01831105 0,02929604 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 19 17 0,000 0,01831105 0,02928292 ! regulation of immunoglobulin mediated immune response GO:0002889 21 17 0,000 0,01831105 0,02926982 GO:0002712|regulation of B cell mediated immunity, ! receptor signaling complex scaffold activity GO:0030159 17 17 0,000 0,01831105 0,02925672 ! positive regulation of cytokine secretion GO:0050715 17 17 0,000 0,01831105 0,02924364 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 17 0,000 0,01831105 0,02923056 ! endodeoxyribonuclease activity GO:0004520 17 17 0,000 0,01831105 0,0292175 ! sphingolipid catabolic process GO:0030149 18 17 0,000 0,01831105 0,02920445 ! steroid catabolic process GO:0006706 17 17 0,000 0,01831105 0,02919142 ! oxygen transport GO:0015671 18 17 0,000 0,01831105 0,02917839 GO:0005344|oxygen transporter activity, ! phosphatidylinositol binding GO:0005545 19 17 0,000 0,01831105 0,02916538 ! hyaluronic acid binding GO:0005540 17 17 0,000 0,01831105 0,02915237 ! negative regulation of T cell activation GO:0050868 17 17 0,000 0,01831105 0,02913938 ! regulation of glucose metabolic process GO:0010906 17 17 0,000 0,01831105 0,0291264 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 17 17 0,000 0,01831105 0,02911343 ! glycosaminoglycan biosynthetic process GO:0006024 17 17 0,000 0,01831105 0,02910048 ! MAP kinase kinase kinase activity GO:0004709 18 17 0,000 0,01831105 0,02908753 ! L-ascorbic acid binding GO:0031418 17 17 0,000 0,01831105 0,0290746 ! negative regulation of endothelial cell proliferation GO:0001937 17 17 0,000 0,01831105 0,02906168 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 18 17 0,000 0,01831105 0,02904877 ! photoreceptor cell maintenance GO:0045494 17 17 0,000 0,01831105 0,02903587 ! response to carbohydrate stimulus GO:0009743 17 17 0,000 0,01831105 0,02902298 ! calmodulin-dependent protein kinase activity GO:0004683 19 17 0,000 0,01831105 0,0290101 ! fucose metabolic process GO:0006004 19 17 0,000 0,01831105 0,02899724 ! D-ribose metabolic process GO:0006014 18 17 0,000 0,01831105 0,02898438 ! membrane budding GO:0006900 18 17 0,000 0,01831105 0,02897154 ! AMP binding GO:0016208 17 17 0,000 0,01831105 0,02895871 ! nuclear ubiquitin ligase complex GO:0000152 17 17 0,000 0,01831105 0,02894589 ! body fluid secretion GO:0007589 18 17 0,000 0,01831105 0,02893308 ! response to fungus GO:0009620 17 17 0,000 0,01831105 0,02892029 ! positive regulation of alpha-beta T cell activation GO:0046635 21 17 0,000 0,01831105 0,0289075 ! intermediate filament-based process GO:0045103 18 17 0,000 0,01831105 0,02889473 ! rRNA binding GO:0019843 17 17 0,000 0,01831105 0,02888197 ! nucleotide-excision repair, DNA gap filling GO:0006297 18 17 0,000 0,01831105 0,02886921 ! regulation of interleukin-2 production GO:0032663 17 17 0,000 0,01831105 0,02885647 ! voltage-gated chloride channel activity GO:0005247 17 17 0,000 0,01831105 0,02884375 ! neutrophil chemotaxis GO:0030593 18 17 0,000 0,01831105 0,02883103 ! long-chain fatty acid transport GO:0015909 17 17 0,000 0,01831105 0,02881832 ! tissue regeneration GO:0042246 17 17 0,000 0,01831105 0,02880563 ! detection of biotic stimulus GO:0009595 18 17 0,000 0,01831105 0,02879294 ! muscle maintenance GO:0046716 18 17 0,000 0,01831105 0,02878027 ! cell-cell junction organization GO:0045216 17 17 0,000 0,01831105 0,02876761 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 17 17 0,000 0,01831105 0,02875496 ! somatic recombination of immunoglobulin gene segments GO:0016447 17 17 0,000 0,01831105 0,02874232 ! cell-cell adherens junction GO:0005913 17 17 0,000 0,01831105 0,02872969 ! triacylglycerol lipase activity GO:0004806 17 17 0,000 0,01831105 0,02871707 ! ATP-dependent DNA helicase activity GO:0004003 17 17 0,000 0,01831105 0,02870447 ! positive regulation of ossification GO:0045778 19 18 0,000 0,01937832 0,03036419 ! pteridine and derivative metabolic process GO:0042558 19 18 0,000 0,01937832 0,03035088 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,01937832 0,03033757 GO:0005763|mitochondrial small ribosomal subunit, ! signal complex assembly GO:0007172 18 18 0,000 0,01937832 0,03032427 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 19 18 0,000 0,01937832 0,03031099 ! limbic system development GO:0021761 18 18 0,000 0,01937832 0,03029772 ! cellular response to hydrogen peroxide GO:0070301 18 18 0,000 0,01937832 0,03028446 GO:0042744|hydrogen peroxide catabolic process, ! MHC class II protein complex GO:0042613 18 18 0,000 0,01937832 0,03027121 ! positive regulation of proteolysis GO:0045862 19 18 0,000 0,01937832 0,03025798 ! deoxyribonucleotide metabolic process GO:0009262 19 18 0,000 0,01937832 0,03024475 ! lysosome organization GO:0007040 18 18 0,000 0,01937832 0,03023154 ! central nervous system neuron development GO:0021954 19 18 0,000 0,01937832 0,03021834 ! fatty acid beta-oxidation GO:0006635 18 18 0,000 0,01937832 0,03020515 ! regulation of viral reproduction GO:0050792 18 18 0,000 0,01937832 0,03019197 ! peptide cross-linking GO:0018149 20 18 0,000 0,01937832 0,0301788 ! ventricular cardiac muscle morphogenesis GO:0055010 19 18 0,000 0,01937832 0,03016565 ! presynaptic membrane GO:0042734 19 18 0,000 0,01937832 0,0301525 ! embryonic digit morphogenesis GO:0042733 20 18 0,000 0,01937832 0,03013937 ! neural crest cell migration GO:0001755 18 18 0,000 0,01937832 0,03012625 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,01937832 0,03011314 ! positive regulation of adaptive immune response GO:0002821 22 18 0,000 0,01937832 0,03010004 ! positive regulation of intracellular transport GO:0032388 19 18 0,000 0,01937832 0,03008695 ! negative regulation of intracellular transport GO:0032387 18 18 0,000 0,01937832 0,03007388 ! peptidyl-serine modification GO:0018209 18 18 0,000 0,01937832 0,03006081 ! cell-cell recognition GO:0009988 19 18 0,000 0,01937832 0,03004776 ! vitamin D receptor binding GO:0042809 19 18 0,000 0,01937832 0,03003472 ! porphyrin biosynthetic process GO:0006779 18 18 0,000 0,01937832 0,03002169 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 18 0,000 0,01937832 0,03000867 ! actin filament-based movement GO:0030048 18 18 0,000 0,01937832 0,02999566 ! Rab GTPase binding GO:0017137 18 18 0,000 0,01937832 0,02998267 ! histone deacetylase activity GO:0004407 19 18 0,000 0,01937832 0,02996968 GO:0033558|protein deacetylase activity, ! negative regulation of cell cycle process GO:0010948 18 18 0,000 0,01937832 0,02995671 ! glycerol metabolic process GO:0006071 19 18 0,000 0,01937832 0,02994375 ! post-Golgi vesicle-mediated transport GO:0006892 18 18 0,000 0,01937832 0,02993079 ! intra-Golgi vesicle-mediated transport GO:0006891 18 18 0,000 0,01937832 0,02991785 ! aminoglycan catabolic process GO:0006026 18 18 0,000 0,01937832 0,02990492 ! aminoglycan biosynthetic process GO:0006023 18 18 0,000 0,01937832 0,02989201 ! small conjugating protein binding GO:0032182 18 18 0,000 0,01937832 0,0298791 ! memory GO:0007613 19 18 0,000 0,01937832 0,0298662 ! C21-steroid hormone metabolic process GO:0008207 18 18 0,000 0,01937832 0,02985332 ! regulation of DNA recombination GO:0000018 22 18 0,000 0,01937832 0,02984045 ! inactivation of MAPK activity GO:0000188 19 18 0,000 0,01937832 0,02982758 ! pigmentation during development GO:0048066 21 18 0,000 0,01937832 0,02981473 ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 18 0,000 0,01937832 0,02980189 ! acetylcholine binding GO:0042166 19 18 0,000 0,01937832 0,02978906 ! neurotransmitter:sodium symporter activity GO:0005328 18 18 0,000 0,01937832 0,02977625 ! neurotransmitter metabolic process GO:0042133 23 18 0,000 0,01937832 0,02976344 ! neuromuscular junction development GO:0007528 21 18 0,000 0,01937832 0,02975064 ! nonmotile primary cilium GO:0031513 19 18 0,000 0,01937832 0,02973786 ! coreceptor activity GO:0015026 18 18 0,000 0,01937832 0,02972508 ! behavioral interaction between organisms GO:0051705 18 18 0,000 0,01937832 0,02971232 ! carbonate dehydratase activity GO:0004089 19 18 0,000 0,01937832 0,02969957 ! cytolysis GO:0019835 18 18 0,000 0,01937832 0,02968683 ! phosphate binding GO:0042301 19 18 0,000 0,01937832 0,0296741 ! transport vesicle membrane GO:0030658 21 18 0,000 0,01937832 0,02966138 ! specific transcriptional repressor activity GO:0016566 18 18 0,000 0,01937832 0,02964867 ! DNA modification GO:0006304 20 18 0,000 0,01937832 0,02963597 ! bicarbonate transmembrane transporter activity GO:0015106 19 18 0,000 0,01937832 0,02962329 ! detection of chemical stimulus GO:0009593 19 18 0,000 0,01937832 0,02961061 ! ionotropic glutamate receptor activity GO:0004970 20 18 0,000 0,01937832 0,02959794 ! aspartic-type endopeptidase activity GO:0004190 19 18 0,000 0,01937832 0,02958529 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 18 18 0,000 0,01937832 0,02957265 ! 3'-5' exonuclease activity GO:0008408 18 18 0,000 0,01937832 0,02956002 ! RNA polymerase II transcription mediator activity GO:0016455 19 18 0,000 0,01937832 0,02954739 ! water-soluble vitamin biosynthetic process GO:0042364 19 18 0,000 0,01937832 0,02953478 ! connexon complex GO:0005922 18 18 0,000 0,01937832 0,02952218 ! solute:hydrogen antiporter activity GO:0015299 18 18 0,000 0,01937832 0,02950959 ! mRNA export from nucleus GO:0006406 21 19 0,000 0,02044451 0,03111992 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 20 19 0,000 0,02044451 0,03110666 ! regulation of interferon-gamma production GO:0032649 20 19 0,000 0,02044451 0,03109341 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 20 19 0,000 0,02044451 0,03108018 ! anion:anion antiporter activity GO:0015301 20 19 0,000 0,02044451 0,03106695 ! cAMP metabolic process GO:0046058 19 19 0,000 0,02044451 0,03105374 ! spindle microtubule GO:0005876 20 19 0,000 0,02044451 0,03104053 ! ovarian follicle development GO:0001541 19 19 0,000 0,02044451 0,03102734 ! retinoid metabolic process GO:0001523 19 19 0,000 0,02044451 0,03101416 GO:0016101|diterpenoid metabolic process, ! caspase activator activity GO:0008656 19 19 0,000 0,02044451 0,03100099 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 21 19 0,000 0,02044451 0,03098783 ! vacuolar transport GO:0007034 19 19 0,000 0,02044451 0,03097469 ! threonine-type endopeptidase activity GO:0004298 19 19 0,000 0,02044451 0,03096155 GO:0070003|threonine-type peptidase activity, ! myofibril assembly GO:0030239 19 19 0,000 0,02044451 0,03094842 GO:0055002|striated muscle cell development, ! monocarboxylic acid transmembrane transporter activity GO:0008028 20 19 0,000 0,02044451 0,03093531 ! positive regulation of multicellular organism growth GO:0040018 19 19 0,000 0,02044451 0,03092221 ! cell projection membrane GO:0031253 20 19 0,000 0,02044451 0,03090912 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,02044451 0,03089604 ! transcriptional repressor complex GO:0017053 19 19 0,000 0,02044451 0,03088297 ! vitamin A metabolic process GO:0006776 19 19 0,000 0,02044451 0,03086991 ! positive regulation of myeloid cell differentiation GO:0045639 20 19 0,000 0,02044451 0,03085686 ! negative regulation of myeloid cell differentiation GO:0045638 19 19 0,000 0,02044451 0,03084383 ! glutamine family amino acid catabolic process GO:0009065 21 19 0,000 0,02044451 0,0308308 ! leukotriene biosynthetic process GO:0019370 19 19 0,000 0,02044451 0,03081779 GO:0043450|alkene biosynthetic process, ! gas transport GO:0015669 20 19 0,000 0,02044451 0,03080478 ! retinoid binding GO:0005501 19 19 0,000 0,02044451 0,03079179 GO:0019840|isoprenoid binding, ! peptide hormone secretion GO:0030072 20 19 0,000 0,02044451 0,03077881 ! protein stabilization GO:0050821 20 19 0,000 0,02044451 0,03076584 ! cellular monovalent inorganic cation homeostasis GO:0030004 20 19 0,000 0,02044451 0,03075288 ! myeloid leukocyte differentiation GO:0002573 21 19 0,000 0,02044451 0,03073993 ! microtubule-based transport GO:0010970 19 19 0,000 0,02044451 0,03072699 ! protein complex scaffold GO:0032947 19 19 0,000 0,02044451 0,03071407 ! SNAP receptor activity GO:0005484 21 19 0,000 0,02044451 0,03070115 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,02044451 0,03068824 GO:0006479|protein amino acid methylation, ! regulation of systemic arterial blood pressure by hormone GO:0001990 19 19 0,000 0,02044451 0,03067535 GO:0050886|endocrine process, ! visual behavior GO:0007632 22 19 0,000 0,02044451 0,03066247 GO:0008542|visual learning, ! 4 iron, 4 sulfur cluster binding GO:0051539 21 19 0,000 0,02044451 0,03064959 ! glycoprotein binding GO:0001948 23 19 0,000 0,02044451 0,03063673 ! sensory perception of taste GO:0050909 19 19 0,000 0,02044451 0,03062388 ! myoblast differentiation GO:0045445 19 19 0,000 0,02044451 0,03061104 ! cell differentiation in spinal cord GO:0021515 19 19 0,000 0,02044451 0,03059821 ! immune response-activating cell surface receptor signaling pathway GO:0002429 25 19 0,000 0,02044451 0,03058539 ! myosin binding GO:0017022 19 19 0,000 0,02044451 0,03057259 ! organic acid:sodium symporter activity GO:0005343 19 19 0,000 0,02044451 0,03055979 ! cell aging GO:0007569 19 19 0,000 0,02044451 0,030547 ! stem cell differentiation GO:0048863 19 19 0,000 0,02044451 0,03053423 ! regulation of myeloid leukocyte differentiation GO:0002761 21 19 0,000 0,02044451 0,03052146 ! heart process GO:0003015 20 19 0,000 0,02044451 0,03050871 GO:0060047|heart contraction, ! mismatch repair GO:0006298 19 19 0,000 0,02044451 0,03049596 ! secretory granule membrane GO:0030667 20 19 0,000 0,02044451 0,03048323 ! MHC protein binding GO:0042287 19 19 0,000 0,02044451 0,03047051 ! extracellular-glutamate-gated ion channel activity GO:0005234 21 19 0,000 0,02044451 0,03045779 ! chloride transmembrane transporter activity GO:0015108 20 19 0,000 0,02044451 0,03044509 ! GABA-A receptor activity GO:0004890 20 19 0,000 0,02044451 0,0304324 ! response to cytokine stimulus GO:0034097 20 19 0,000 0,02044451 0,03041972 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,02044451 0,03040705 ! translation elongation factor activity GO:0003746 22 19 0,000 0,02044451 0,03039439 ! insulin receptor binding GO:0005158 20 19 0,000 0,02044451 0,03038175 ! phosphoprotein phosphatase inhibitor activity GO:0004864 21 19 0,000 0,02044451 0,03036911 ! protein secretion GO:0009306 20 20 0,000 0,0215096 0,03193796 ! positive regulation of angiogenesis GO:0045766 22 20 0,000 0,0215096 0,03192468 ! proteasome core complex GO:0005839 20 20 0,000 0,0215096 0,03191142 ! positive regulation of bone remodeling GO:0046852 21 20 0,000 0,0215096 0,03189817 ! heterophilic cell adhesion GO:0007157 21 20 0,000 0,0215096 0,03188493 ! glutathione transferase activity GO:0004364 20 20 0,000 0,0215096 0,0318717 ! microtubule organizing center organization GO:0031023 20 20 0,000 0,0215096 0,03185848 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 20 20 0,000 0,0215096 0,03184527 ! actomyosin GO:0042641 20 20 0,000 0,0215096 0,03183207 ! positive regulation of innate immune response GO:0045089 20 20 0,000 0,0215096 0,03181889 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 20 0,000 0,0215096 0,03180571 ! vacuole organization GO:0007033 20 20 0,000 0,0215096 0,03179255 ! oxidoreductase activity, acting on heme group of donors GO:0016675 21 20 0,000 0,0215096 0,03177939 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! purine ribonucleoside metabolic process GO:0046128 23 20 0,000 0,0215096 0,03176625 GO:0042278|purine nucleoside metabolic process, ! chromosome condensation GO:0030261 20 20 0,000 0,0215096 0,03175312 ! regulation of exocytosis GO:0017157 21 20 0,000 0,0215096 0,03174 ! vitamin biosynthetic process GO:0009110 21 20 0,000 0,0215096 0,03172689 ! glycosphingolipid metabolic process GO:0006687 20 20 0,000 0,0215096 0,03171379 ! kinase activator activity GO:0019209 20 20 0,000 0,0215096 0,0317007 ! diencephalon development GO:0021536 20 20 0,000 0,0215096 0,03168762 ! nuclear inner membrane GO:0005637 20 20 0,000 0,0215096 0,03167455 ! positive regulation of locomotion GO:0040017 20 20 0,000 0,0215096 0,0316615 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! synaptic vesicle transport GO:0048489 21 20 0,000 0,0215096 0,03164845 ! proteoglycan biosynthetic process GO:0030166 20 20 0,000 0,0215096 0,03163542 ! negative regulation of Wnt receptor signaling pathway GO:0030178 21 20 0,000 0,0215096 0,03162239 ! leukocyte homeostasis GO:0001776 22 20 0,000 0,0215096 0,03160938 ! regulation of blood coagulation GO:0030193 22 20 0,000 0,0215096 0,03159638 ! positive regulation of osteoblast differentiation GO:0045669 22 20 0,000 0,0215096 0,03158338 ! regulation of generation of precursor metabolites and energy GO:0043467 21 20 0,000 0,0215096 0,0315704 ! ligase activity, forming carbon-sulfur bonds GO:0016877 20 20 0,000 0,0215096 0,03155743 ! phosphorus-oxygen lyase activity GO:0016849 20 20 0,000 0,0215096 0,03154447 ! embryonic organ morphogenesis GO:0048562 22 20 0,000 0,0215096 0,03153152 ! alditol metabolic process GO:0019400 21 20 0,000 0,0215096 0,03151859 ! liver development GO:0001889 20 20 0,000 0,0215096 0,03150566 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 20 0,000 0,0215096 0,03149274 ! chromosome, telomeric region GO:0000781 21 20 0,000 0,0215096 0,03147983 ! calcium-independent cell-cell adhesion GO:0016338 20 20 0,000 0,0215096 0,03146694 ! response to alkaloid GO:0043279 22 20 0,000 0,0215096 0,03145405 ! transmembrane receptor protein phosphatase activity GO:0019198 27 20 0,000 0,0215096 0,03144118 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! smooth muscle contraction GO:0006939 21 20 0,000 0,0215096 0,03142831 ! heme metabolic process GO:0042168 22 20 0,000 0,0215096 0,03141546 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 20 20 0,000 0,0215096 0,03140261 ! sex determination GO:0007530 20 20 0,000 0,0215096 0,03138978 ! negative regulation of protein catabolic process GO:0042177 21 20 0,000 0,0215096 0,03137696 ! peptide secretion GO:0002790 21 20 0,000 0,0215096 0,03136415 ! regulation of alpha-beta T cell activation GO:0046634 24 20 0,000 0,0215096 0,03135134 ! interaction with host GO:0051701 24 20 0,000 0,0215096 0,03133855 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 26 20 0,000 0,0215096 0,03132577 ! vasodilation GO:0042311 21 20 0,000 0,0215096 0,031313 ! regulation of tumor necrosis factor production GO:0032680 20 20 0,000 0,0215096 0,03130024 ! regulation of chromosome organization GO:0033044 20 20 0,000 0,0215096 0,03128749 ! inward rectifier potassium channel activity GO:0005242 20 20 0,000 0,0215096 0,03127475 ! activation of JUN kinase activity GO:0007257 20 20 0,000 0,0215096 0,03126202 ! cyclic nucleotide binding GO:0030551 22 20 0,000 0,0215096 0,03124931 ! somatic diversification of immunoglobulins GO:0016445 20 20 0,000 0,0215096 0,0312366 ! microvillus GO:0005902 20 20 0,000 0,0215096 0,0312239 ! tumor necrosis factor receptor binding GO:0005164 20 20 0,000 0,0215096 0,03121121 ! ATP-dependent RNA helicase activity GO:0004004 20 20 0,000 0,0215096 0,03119853 ! positive regulation of protein catabolic process GO:0045732 22 21 0,000 0,02257361 0,03272853 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 22 21 0,000 0,02257361 0,03271525 ! growth cone GO:0030426 22 21 0,000 0,02257361 0,03270198 ! oligosaccharide metabolic process GO:0009311 23 21 0,000 0,02257361 0,03268872 ! regulation of anti-apoptosis GO:0045767 21 21 0,000 0,02257361 0,03267547 ! hormone secretion GO:0046879 22 21 0,000 0,02257361 0,03266223 ! protein amino acid O-linked glycosylation GO:0006493 22 21 0,000 0,02257361 0,032649 ! transition metal ion transmembrane transporter activity GO:0046915 21 21 0,000 0,02257361 0,03263578 ! voltage-gated calcium channel complex GO:0005891 24 21 0,000 0,02257361 0,03262257 GO:0034704|calcium channel complex, ! dicarboxylic acid metabolic process GO:0043648 22 21 0,000 0,02257361 0,03260937 ! protein phosphatase type 2A regulator activity GO:0008601 23 21 0,000 0,02257361 0,03259619 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 24 21 0,000 0,02257361 0,03258301 ! histone-lysine N-methyltransferase activity GO:0018024 23 21 0,000 0,02257361 0,03256985 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! activation of pro-apoptotic gene products GO:0008633 22 21 0,000 0,02257361 0,03255669 ! mitochondrial membrane organization GO:0007006 22 21 0,000 0,02257361 0,03254355 ! central nervous system neuron differentiation GO:0021953 22 21 0,000 0,02257361 0,03253042 ! Golgi stack GO:0005795 25 21 0,000 0,02257361 0,03251729 ! regulation of endothelial cell migration GO:0010594 21 21 0,000 0,02257361 0,03250418 ! muscle cell development GO:0055001 21 21 0,000 0,02257361 0,03249108 ! cholesterol biosynthetic process GO:0006695 22 21 0,000 0,02257361 0,03247799 ! regulation of vasoconstriction GO:0019229 22 21 0,000 0,02257361 0,03246491 ! deacetylase activity GO:0019213 22 21 0,000 0,02257361 0,03245184 ! phosphatase inhibitor activity GO:0019212 23 21 0,000 0,02257361 0,03243878 ! regulation of fatty acid metabolic process GO:0019217 22 21 0,000 0,02257361 0,03242573 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,02257361 0,03241269 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! sensory perception of pain GO:0019233 21 21 0,000 0,02257361 0,03239967 ! pentose metabolic process GO:0019321 22 21 0,000 0,02257361 0,03238665 ! collagen fibril organization GO:0030199 22 21 0,000 0,02257361 0,03237364 ! platelet activation GO:0030168 23 21 0,000 0,02257361 0,03236065 ! response to glucocorticoid stimulus GO:0051384 22 21 0,000 0,02257361 0,03234766 ! trans-Golgi network transport vesicle GO:0030140 24 21 0,000 0,02257361 0,03233469 ! glutathione metabolic process GO:0006749 21 21 0,000 0,02257361 0,03232172 ! DNA-directed RNA polymerase complex GO:0000428 22 21 0,000 0,02257361 0,03230877 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! terpenoid metabolic process GO:0006721 21 21 0,000 0,02257361 0,03229582 ! cyclase activity GO:0009975 21 21 0,000 0,02257361 0,03228289 ! intramolecular transferase activity GO:0016866 22 21 0,000 0,02257361 0,03226996 ! negative regulation of cytokine production GO:0001818 21 21 0,000 0,02257361 0,03225705 ! fatty acid binding GO:0005504 21 21 0,000 0,02257361 0,03224415 ! gut development GO:0048565 21 21 0,000 0,02257361 0,03223126 ! acetyl-CoA catabolic process GO:0046356 21 21 0,000 0,02257361 0,03221837 GO:0006099|tricarboxylic acid cycle, ! phosphoinositide phospholipase C activity GO:0004435 21 21 0,000 0,02257361 0,0322055 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! protein tetramerization GO:0051262 22 21 0,000 0,02257361 0,03219264 ! regulation of microtubule polymerization or depolymerization GO:0031110 23 21 0,000 0,02257361 0,03217979 ! sulfur amino acid metabolic process GO:0000096 22 21 0,000 0,02257361 0,03216695 ! voltage-gated anion channel activity GO:0008308 21 21 0,000 0,02257361 0,03215412 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,02257361 0,0321413 ! cellular polysaccharide biosynthetic process GO:0033692 21 21 0,000 0,02257361 0,03212849 ! positive regulation of JAK-STAT cascade GO:0046427 22 21 0,000 0,02257361 0,03211569 ! sterol binding GO:0032934 21 21 0,000 0,02257361 0,0321029 ! regulation of chemotaxis GO:0050920 21 21 0,000 0,02257361 0,03209012 ! regulation of carbohydrate metabolic process GO:0006109 22 21 0,000 0,02257361 0,03207735 GO:0010675|regulation of cellular carbohydrate metabolic process, ! superoxide metabolic process GO:0006801 21 21 0,000 0,02257361 0,03206459 ! calcium-dependent cell-cell adhesion GO:0016339 21 21 0,000 0,02257361 0,03205184 ! phosphatase binding GO:0019902 22 21 0,000 0,02257361 0,0320391 ! NAD+ ADP-ribosyltransferase activity GO:0003950 21 21 0,000 0,02257361 0,03202637 ! positive regulation of cytoskeleton organization GO:0051495 21 21 0,000 0,02257361 0,03201365 ! negative regulation of DNA replication GO:0008156 25 21 0,000 0,02257361 0,03200094 ! vesicle targeting GO:0006903 22 21 0,000 0,02257361 0,03198824 ! vesicle docking during exocytosis GO:0006904 21 21 0,000 0,02257361 0,03197555 ! RNA-dependent ATPase activity GO:0008186 21 21 0,000 0,02257361 0,03196288 ! renal system process GO:0003014 22 21 0,000 0,02257361 0,03195021 ! base-excision repair GO:0006284 21 21 0,000 0,02257361 0,03193755 ! positive regulation of leukocyte mediated immunity GO:0002705 25 21 0,000 0,02257361 0,0319249 GO:0002708|positive regulation of lymphocyte mediated immunity, ! nuclear-transcribed mRNA catabolic process GO:0000956 22 21 0,000 0,02257361 0,03191226 ! apoptotic protease activator activity GO:0016505 21 21 0,000 0,02257361 0,03189963 ! fatty acid transport GO:0015908 21 21 0,000 0,02257361 0,03188701 ! sarcoplasmic reticulum GO:0016529 22 21 0,000 0,02257361 0,03187441 ! positive regulation of tissue remodeling GO:0034105 22 21 0,000 0,02257361 0,03186181 ! collagen catabolic process GO:0030574 21 21 0,000 0,02257361 0,03184922 ! pyrimidine nucleotide biosynthetic process GO:0006221 25 21 0,000 0,02257361 0,03183664 ! regulation of multi-organism process GO:0043900 21 21 0,000 0,02257361 0,03182407 ! ubiquitin-specific protease activity GO:0004843 22 21 0,000 0,02257361 0,03181151 ! positive regulation of DNA replication GO:0045740 23 22 0,000 0,02363654 0,03329628 ! site of polarized growth GO:0030427 23 22 0,000 0,02363654 0,03328315 ! leukocyte adhesion GO:0007159 27 22 0,000 0,02363654 0,03327004 ! glutamate signaling pathway GO:0007215 25 22 0,000 0,02363654 0,03325693 ! potassium channel regulator activity GO:0015459 24 22 0,000 0,02363654 0,03324383 ! peroxisome organization GO:0007031 22 22 0,000 0,02363654 0,03323074 ! cellular response to reactive oxygen species GO:0034614 22 22 0,000 0,02363654 0,03321766 ! polysaccharide catabolic process GO:0000272 22 22 0,000 0,02363654 0,03320459 ! response to starvation GO:0042594 23 22 0,000 0,02363654 0,03319154 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 22 22 0,000 0,02363654 0,03317849 ! coenzyme catabolic process GO:0009109 22 22 0,000 0,02363654 0,03316545 ! regulation of insulin secretion GO:0050796 23 22 0,000 0,02363654 0,03315243 ! membrane depolarization GO:0051899 24 22 0,000 0,02363654 0,03313941 ! somitogenesis GO:0001756 23 22 0,000 0,02363654 0,0331264 ! regulation of cytokine secretion GO:0050707 22 22 0,000 0,02363654 0,03311341 ! natural killer cell activation GO:0030101 22 22 0,000 0,02363654 0,03310042 ! aromatic amino acid family metabolic process GO:0009072 25 22 0,000 0,02363654 0,03308745 ! basal plasma membrane GO:0009925 22 22 0,000 0,02363654 0,03307448 GO:0045178|basal part of cell, ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 22 22 0,000 0,02363654 0,03306153 ! camera-type eye morphogenesis GO:0048593 25 22 0,000 0,02363654 0,03304858 ! telomere organization GO:0032200 23 22 0,000 0,02363654 0,03303565 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 24 22 0,000 0,02363654 0,03302272 GO:0060606|tube closure, ! response to molecule of bacterial origin GO:0002237 22 22 0,000 0,02363654 0,03300981 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 22 0,000 0,02363654 0,0329969 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 22 22 0,000 0,02363654 0,03298401 GO:0016444|somatic cell DNA recombination, ! cortical actin cytoskeleton GO:0030864 22 22 0,000 0,02363654 0,03297112 ! initiation of viral infection GO:0019059 22 22 0,000 0,02363654 0,03295825 ! RNA polymerase complex GO:0030880 23 22 0,000 0,02363654 0,03294539 ! regulation of neurotransmitter transport GO:0051588 23 22 0,000 0,02363654 0,03293253 ! macromolecular complex disassembly GO:0032984 23 22 0,000 0,02363654 0,03291969 ! response to ethanol GO:0045471 25 22 0,000 0,02363654 0,03290685 ! syntaxin binding GO:0019905 23 22 0,000 0,02363654 0,03289403 ! regulation of nitric oxide biosynthetic process GO:0045428 22 22 0,000 0,02363654 0,03288122 ! digestive system process GO:0022600 24 22 0,000 0,02363654 0,03286841 ! neurotransmitter transporter activity GO:0005326 22 22 0,000 0,02363654 0,03285562 ! autophagy GO:0006914 24 22 0,000 0,02363654 0,03284283 ! carbohydrate kinase activity GO:0019200 22 22 0,000 0,02363654 0,03283006 ! neuropeptide hormone activity GO:0005184 23 22 0,000 0,02363654 0,03281729 ! transaminase activity GO:0008483 23 22 0,000 0,02363654 0,03280454 ! sarcoplasm GO:0016528 23 22 0,000 0,02363654 0,03279179 ! cellular response to nutrient levels GO:0031669 23 22 0,000 0,02363654 0,03277906 ! positive regulation of nuclear division GO:0051785 22 22 0,000 0,02363654 0,03276634 GO:0045840|positive regulation of mitosis, ! nerve-nerve synaptic transmission GO:0007270 25 22 0,000 0,02363654 0,03275362 ! small conjugating protein-specific protease activity GO:0019783 24 22 0,000 0,02363654 0,03274092 ! pyrimidine nucleoside metabolic process GO:0006213 25 22 0,000 0,02363654 0,03272822 ! solute:cation antiporter activity GO:0015298 22 22 0,000 0,02363654 0,03271553 ! translational initiation GO:0006413 23 23 0,000 0,02469838 0,03417199 ! NF-kappaB binding GO:0051059 23 23 0,000 0,02469838 0,03415876 ! vesicle docking GO:0048278 23 23 0,000 0,02469838 0,03414553 ! muscle myosin complex GO:0005859 25 23 0,000 0,02469838 0,03413232 ! vasculogenesis GO:0001570 25 23 0,000 0,02469838 0,03411912 ! regulation of innate immune response GO:0045088 23 23 0,000 0,02469838 0,03410592 ! positive regulation of epithelial cell proliferation GO:0050679 24 23 0,000 0,02469838 0,03409274 ! sperm motility GO:0030317 23 23 0,000 0,02469838 0,03407957 ! response to corticosteroid stimulus GO:0031960 24 23 0,000 0,02469838 0,0340664 ! barbed-end actin filament capping GO:0051016 23 23 0,000 0,02469838 0,03405325 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 24 23 0,000 0,02469838 0,03404011 ! regulation of behavior GO:0050795 23 23 0,000 0,02469838 0,03402697 ! cardiac muscle tissue morphogenesis GO:0055008 24 23 0,000 0,02469838 0,03401385 GO:0060415|muscle tissue morphogenesis, ! cyclic nucleotide biosynthetic process GO:0009190 23 23 0,000 0,02469838 0,03400074 ! leukotriene metabolic process GO:0006691 23 23 0,000 0,02469838 0,03398764 ! positive regulation of T cell differentiation GO:0045582 27 23 0,000 0,02469838 0,03397454 ! glycolipid metabolic process GO:0006664 23 23 0,000 0,02469838 0,03396146 ! pallium development GO:0021543 23 23 0,000 0,02469838 0,03394839 ! GABA receptor activity GO:0016917 24 23 0,000 0,02469838 0,03393533 ! positive regulation of MAPKKK cascade GO:0043410 30 23 0,000 0,02469838 0,03392228 ! regulation of response to biotic stimulus GO:0002831 23 23 0,000 0,02469838 0,03390923 ! MHC class II receptor activity GO:0032395 23 23 0,000 0,02469838 0,0338962 ! nicotinamide metabolic process GO:0006769 23 23 0,000 0,02469838 0,03388318 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of neuron differentiation GO:0045665 23 23 0,000 0,02469838 0,03387017 ! aspartate family amino acid metabolic process GO:0009066 24 23 0,000 0,02469838 0,03385717 ! cell surface binding GO:0043498 25 23 0,000 0,02469838 0,03384417 ! collagen binding GO:0005518 27 23 0,000 0,02469838 0,03383119 ! insulin-like growth factor binding GO:0005520 23 23 0,000 0,02469838 0,03381822 ! regulation of amine transport GO:0051952 23 23 0,000 0,02469838 0,03380526 ! tissue homeostasis GO:0001894 24 23 0,000 0,02469838 0,0337923 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 25 23 0,000 0,02469838 0,03377936 ! protein import into nucleus, translocation GO:0000060 25 23 0,000 0,02469838 0,03376643 ! gluconeogenesis GO:0006094 24 23 0,000 0,02469838 0,03375351 ! iron ion transport GO:0006826 24 23 0,000 0,02469838 0,0337406 ! nucleotide-excision repair, DNA damage removal GO:0000718 24 23 0,000 0,02469838 0,03372769 ! N-acetylglucosamine metabolic process GO:0006044 23 23 0,000 0,02469838 0,0337148 ! molting cycle process GO:0022404 23 23 0,000 0,02469838 0,03370192 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! circadian rhythm GO:0007623 24 23 0,000 0,02469838 0,03368904 ! tube lumen formation GO:0035148 26 23 0,000 0,02469838 0,03367618 ! insulin receptor signaling pathway GO:0008286 28 23 0,000 0,02469838 0,03366333 ! multicellular organismal response to stress GO:0033555 23 23 0,000 0,02469838 0,03365048 ! immune response-activating signal transduction GO:0002757 29 23 0,000 0,02469838 0,03363765 ! lymphocyte proliferation GO:0046651 29 23 0,000 0,02469838 0,03362483 ! fibroblast growth factor receptor signaling pathway GO:0008543 24 23 0,000 0,02469838 0,03361201 ! regulation of bone mineralization GO:0030500 25 23 0,000 0,02469838 0,03359921 ! single-stranded RNA binding GO:0003727 24 23 0,000 0,02469838 0,03358641 ! brush border GO:0005903 25 23 0,000 0,02469838 0,03357363 ! caveola GO:0005901 24 23 0,000 0,02469838 0,03356085 ! gap junction GO:0005921 23 23 0,000 0,02469838 0,03354809 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 25 24 0,000 0,02575914 0,03497562 ! regulation of transmembrane transport GO:0034762 24 24 0,000 0,02575914 0,03496233 ! heterotrimeric G-protein complex GO:0005834 24 24 0,000 0,02575914 0,03494905 ! protein amino acid acylation GO:0043543 26 24 0,000 0,02575914 0,03493577 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 24 0,000 0,02575914 0,03492251 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 25 24 0,000 0,02575914 0,03490925 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,02575914 0,03489601 ! MHC class I protein complex GO:0042612 24 24 0,000 0,02575914 0,03488278 ! G-protein chemoattractant receptor activity GO:0001637 24 24 0,000 0,02575914 0,03486956 GO:0004950|chemokine receptor activity, ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 24 24 0,000 0,02575914 0,03485634 ! early endosome membrane GO:0031901 26 24 0,000 0,02575914 0,03484314 ! primary neural tube formation GO:0014020 26 24 0,000 0,02575914 0,03482995 ! hydrogen peroxide metabolic process GO:0042743 24 24 0,000 0,02575914 0,03481676 ! immunoglobulin production GO:0002377 28 24 0,000 0,02575914 0,03480359 GO:0002440|production of molecular mediator of immune response, ! lipid kinase activity GO:0001727 26 24 0,000 0,02575914 0,03479043 ! positive regulation of protein secretion GO:0050714 26 24 0,000 0,02575914 0,03477727 ! MHC class I receptor activity GO:0032393 24 24 0,000 0,02575914 0,03476413 ! RNA splicing factor activity, transesterification mechanism GO:0031202 24 24 0,000 0,02575914 0,034751 ! fat-soluble vitamin metabolic process GO:0006775 24 24 0,000 0,02575914 0,03473787 ! regulation of osteoblast differentiation GO:0045667 27 24 0,000 0,02575914 0,03472476 ! cellular alkene metabolic process GO:0043449 24 24 0,000 0,02575914 0,03471166 ! somatic diversification of immune receptors GO:0002200 24 24 0,000 0,02575914 0,03469856 ! calcium-dependent phospholipid binding GO:0005544 24 24 0,000 0,02575914 0,03468548 ! positive regulation of JUN kinase activity GO:0043507 24 24 0,000 0,02575914 0,0346724 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 26 24 0,000 0,02575914 0,03465934 ! Z disc GO:0030018 27 24 0,000 0,02575914 0,03464628 ! negative regulation of lymphocyte activation GO:0051250 24 24 0,000 0,02575914 0,03463324 ! alkaloid metabolic process GO:0009820 24 24 0,000 0,02575914 0,03462021 ! neuron fate commitment GO:0048663 24 24 0,000 0,02575914 0,03460718 ! glucosamine metabolic process GO:0006041 24 24 0,000 0,02575914 0,03459417 ! regulation of transcription factor import into nucleus GO:0042990 25 24 0,000 0,02575914 0,03458116 ! glucose transport GO:0015758 24 24 0,000 0,02575914 0,03456816 ! dendrite development GO:0016358 26 24 0,000 0,02575914 0,03455518 ! catechol metabolic process GO:0009712 27 24 0,000 0,02575914 0,0345422 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! phospholipase A2 activity GO:0004623 26 24 0,000 0,02575914 0,03452924 ! immune response-regulating signal transduction GO:0002764 30 24 0,000 0,02575914 0,03451628 ! regulation of production of molecular mediator of immune response GO:0002700 28 24 0,000 0,02575914 0,03450333 ! DNA-directed DNA polymerase activity GO:0003887 25 24 0,000 0,02575914 0,0344904 ! synaptogenesis GO:0007416 25 24 0,000 0,02575914 0,03447747 ! selenium binding GO:0008430 24 24 0,000 0,02575914 0,03446455 ! leukocyte proliferation GO:0070661 30 24 0,000 0,02575914 0,03445164 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 26 24 0,000 0,02575914 0,03443874 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 25 25 0,000 0,02681882 0,03584206 ! phenol metabolic process GO:0018958 28 25 0,000 0,02681882 0,03582865 ! myelination GO:0042552 26 25 0,000 0,02681882 0,03581526 ! epidermal growth factor receptor signaling pathway GO:0007173 28 25 0,000 0,02681882 0,03580187 ! hexose transport GO:0008645 25 25 0,000 0,02681882 0,03578849 GO:0015749|monosaccharide transport, ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 27 25 0,000 0,02681882 0,03577512 ! PML body GO:0016605 28 25 0,000 0,02681882 0,03576176 ! regulation of cellular ketone metabolic process GO:0010565 26 25 0,000 0,02681882 0,03574841 ! negative regulation of cell development GO:0010721 28 25 0,000 0,02681882 0,03573507 GO:0050768|negative regulation of neurogenesis, ! regulation of biomineral formation GO:0070167 27 25 0,000 0,02681882 0,03572174 ! cell fate determination GO:0001709 25 25 0,000 0,02681882 0,03570842 ! regulation of oxidoreductase activity GO:0051341 25 25 0,000 0,02681882 0,03569512 ! group transfer coenzyme metabolic process GO:0006752 26 25 0,000 0,02681882 0,03568182 ! hormone transport GO:0009914 26 25 0,000 0,02681882 0,03566853 ! neuromuscular process controlling balance GO:0050885 26 25 0,000 0,02681882 0,03565525 ! porphyrin metabolic process GO:0006778 27 25 0,000 0,02681882 0,03564198 GO:0033013|tetrapyrrole metabolic process, ! blastocyst development GO:0001824 25 25 0,000 0,02681882 0,03562872 ! regulation of JUN kinase activity GO:0043506 25 25 0,000 0,02681882 0,03561547 ! cell adhesion molecule binding GO:0050839 27 25 0,000 0,02681882 0,03560223 ! negative regulation of actin filament depolymerization GO:0030835 25 25 0,000 0,02681882 0,035589 ! acetyl-CoA metabolic process GO:0006084 25 25 0,000 0,02681882 0,03557578 ! membrane lipid catabolic process GO:0046466 26 25 0,000 0,02681882 0,03556257 ! zinc ion transport GO:0006829 26 25 0,000 0,02681882 0,03554937 ! heterochromatin GO:0000792 26 25 0,000 0,02681882 0,03553618 ! cellular iron ion homeostasis GO:0006879 25 25 0,000 0,02681882 0,03552299 ! phototransduction GO:0007602 25 25 0,000 0,02681882 0,03550982 ! keratinization GO:0031424 26 25 0,000 0,02681882 0,03549666 ! spinal cord development GO:0021510 25 25 0,000 0,02681882 0,03548351 ! cyclin-dependent protein kinase activity GO:0004693 26 25 0,000 0,02681882 0,03547037 ! regulation of smooth muscle contraction GO:0006940 28 25 0,000 0,02681882 0,03545724 ! response to toxin GO:0009636 25 25 0,000 0,02681882 0,03544411 ! regulation of peptide secretion GO:0002791 26 25 0,000 0,02681882 0,035431 ! determination of left/right symmetry GO:0007368 25 25 0,000 0,02681882 0,0354179 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 25 0,000 0,02681882 0,0354048 ! regulation of interleukin-6 production GO:0032675 25 25 0,000 0,02681882 0,03539172 ! voltage-gated calcium channel activity GO:0005245 28 25 0,000 0,02681882 0,03537865 ! phospholipid transport GO:0015914 26 25 0,000 0,02681882 0,03536558 ! peptidase activator activity GO:0016504 25 25 0,000 0,02681882 0,03535253 ! protein localization in mitochondrion GO:0070585 26 25 0,000 0,02681882 0,03533948 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 25 25 0,000 0,02681882 0,03532645 ! ethanolamine and derivative metabolic process GO:0042439 28 25 0,000 0,02681882 0,03531342 ! small nuclear ribonucleoprotein complex GO:0030532 25 25 0,000 0,02681882 0,0353004 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 25 25 0,000 0,02681882 0,0352874 ! negative regulation of transcription regulator activity GO:0090048 26 25 0,000 0,02681882 0,0352744 GO:0043433|negative regulation of transcription factor activity, ! acetylgalactosaminyltransferase activity GO:0008376 27 25 0,000 0,02681882 0,03526141 ! solute:solute antiporter activity GO:0015300 26 26 0,000 0,02787741 0,03663977 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 27 26 0,000 0,02787741 0,03662629 ! regeneration GO:0031099 26 26 0,000 0,02787741 0,03661281 ! cholesterol homeostasis GO:0042632 26 26 0,000 0,02787741 0,03659935 GO:0055092|sterol homeostasis, ! peptidyl-tyrosine phosphorylation GO:0018108 27 26 0,000 0,02787741 0,0365859 ! ureteric bud development GO:0001657 26 26 0,000 0,02787741 0,03657246 ! neural crest cell development GO:0014032 26 26 0,000 0,02787741 0,03655903 GO:0014033|neural crest cell differentiation, ! negative regulation of protein kinase cascade GO:0010741 27 26 0,000 0,02787741 0,03654561 ! cellular response to oxidative stress GO:0034599 26 26 0,000 0,02787741 0,0365322 ! lipid oxidation GO:0034440 26 26 0,000 0,02787741 0,0365188 GO:0019395|fatty acid oxidation, ! positive regulation of lymphocyte differentiation GO:0045621 30 26 0,000 0,02787741 0,03650541 ! pyridine nucleotide metabolic process GO:0019362 26 26 0,000 0,02787741 0,03649202 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 26 26 0,000 0,02787741 0,03647865 ! carboxy-lyase activity GO:0016831 26 26 0,000 0,02787741 0,03646529 ! myeloid leukocyte activation GO:0002274 27 26 0,000 0,02787741 0,03645194 ! negative regulation of neuron apoptosis GO:0043524 26 26 0,000 0,02787741 0,0364386 ! negative regulation of catabolic process GO:0009895 28 26 0,000 0,02787741 0,03642526 ! lysine N-acetyltransferase activity GO:0004468 26 26 0,000 0,02787741 0,03641194 GO:0004402|histone acetyltransferase activity, ! regulation of actin filament depolymerization GO:0030834 26 26 0,000 0,02787741 0,03639863 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,02787741 0,03638532 ! determination of bilateral symmetry GO:0009855 26 26 0,000 0,02787741 0,03637203 GO:0009799|determination of symmetry, ! regulation of cellular catabolic process GO:0031329 28 26 0,000 0,02787741 0,03635874 ! pyruvate metabolic process GO:0006090 27 26 0,000 0,02787741 0,03634547 ! cellular component assembly involved in morphogenesis GO:0010927 26 26 0,000 0,02787741 0,03633221 ! histone methyltransferase activity GO:0042054 29 26 0,000 0,02787741 0,03631895 ! regulation of endothelial cell proliferation GO:0001936 27 26 0,000 0,02787741 0,03630571 ! chemokine binding GO:0019956 26 26 0,000 0,02787741 0,03629247 ! receptor metabolic process GO:0043112 28 26 0,000 0,02787741 0,03627924 ! nucleotide kinase activity GO:0019201 30 26 0,000 0,02787741 0,03626603 ! histone deacetylase complex GO:0000118 27 26 0,000 0,02787741 0,03625282 ! phospholipase C activity GO:0004629 27 26 0,000 0,02787741 0,03623962 ! negative regulation of leukocyte activation GO:0002695 26 26 0,000 0,02787741 0,03622643 ! receptor regulator activity GO:0030545 26 26 0,000 0,02787741 0,03621326 ! galactosyltransferase activity GO:0008378 27 26 0,000 0,02787741 0,03620009 ! positive regulation of immune effector process GO:0002699 30 26 0,000 0,02787741 0,03618693 ! mRNA catabolic process GO:0006402 28 27 0,000 0,02893493 0,03754602 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 28 27 0,000 0,02893493 0,03753238 ! actomyosin structure organization GO:0031032 28 27 0,000 0,02893493 0,03751875 ! nucleotide receptor activity, G-protein coupled GO:0001608 27 27 0,000 0,02893493 0,03750513 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! iron ion homeostasis GO:0055072 27 27 0,000 0,02893493 0,03749152 ! lipoprotein binding GO:0008034 29 27 0,000 0,02893493 0,03747792 ! mesoderm formation GO:0001707 28 27 0,000 0,02893493 0,03746434 ! phospholipid transporter activity GO:0005548 29 27 0,000 0,02893493 0,03745076 ! neural tube formation GO:0001841 29 27 0,000 0,02893493 0,03743719 ! mitotic sister chromatid segregation GO:0000070 27 27 0,000 0,02893493 0,03742363 ! regulation of smooth muscle cell proliferation GO:0048660 27 27 0,000 0,02893493 0,03741008 ! integrin complex GO:0008305 28 27 0,000 0,02893493 0,03739654 ! collagen metabolic process GO:0032963 27 27 0,000 0,02893493 0,03738301 ! post-embryonic development GO:0009791 29 27 0,000 0,02893493 0,03736949 ! antigen processing and presentation of peptide antigen GO:0048002 28 27 0,000 0,02893493 0,03735598 ! ovulation cycle process GO:0022602 27 27 0,000 0,02893493 0,03734248 ! SNARE binding GO:0000149 28 27 0,000 0,02893493 0,03732899 ! biogenic amine biosynthetic process GO:0042401 28 27 0,000 0,02893493 0,03731551 ! spindle pole GO:0000922 28 27 0,000 0,02893493 0,03730203 ! anion:cation symporter activity GO:0015296 28 27 0,000 0,02893493 0,03728857 ! trans-Golgi network GO:0005802 29 28 0,000 0,02999137 0,03863607 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 28 0,000 0,02999137 0,03862213 ! cholesterol transport GO:0030301 28 28 0,000 0,02999137 0,03860821 GO:0015918|sterol transport, ! thyroid hormone receptor binding GO:0046966 29 28 0,000 0,02999137 0,0385943 ! dynein complex GO:0030286 29 28 0,000 0,02999137 0,0385804 ! formation of primary germ layer GO:0001704 29 28 0,000 0,02999137 0,0385665 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 30 28 0,000 0,02999137 0,03855262 ! ovulation cycle GO:0042698 28 28 0,000 0,02999137 0,03853875 ! peptidyl-tyrosine modification GO:0018212 29 28 0,000 0,02999137 0,03852488 ! deoxyribonuclease activity GO:0004536 28 28 0,000 0,02999137 0,03851103 ! cofactor catabolic process GO:0051187 30 28 0,000 0,02999137 0,03849719 ! DNA damage checkpoint GO:0000077 31 28 0,000 0,02999137 0,03848336 ! negative regulation of actin filament polymerization GO:0030837 28 28 0,000 0,02999137 0,03846953 ! cortical cytoskeleton GO:0030863 29 28 0,000 0,02999137 0,03845572 ! icosanoid biosynthetic process GO:0046456 29 28 0,000 0,02999137 0,03844192 ! amino sugar metabolic process GO:0006040 28 28 0,000 0,02999137 0,03842812 ! membrane docking GO:0022406 28 28 0,000 0,02999137 0,03841434 ! sister chromatid segregation GO:0000819 28 28 0,000 0,02999137 0,03840057 ! detection of light stimulus involved in sensory perception GO:0050962 28 28 0,000 0,02999137 0,0383868 GO:0050908|detection of light stimulus involved in visual perception, ! cell junction assembly GO:0034329 30 28 0,000 0,02999137 0,03837305 ! complement activation, classical pathway GO:0006958 31 28 0,000 0,02999137 0,0383593 ! multicellular organismal catabolic process GO:0044243 28 28 0,000 0,02999137 0,03834557 ! response to mechanical stimulus GO:0009612 28 28 0,000 0,02999137 0,03833185 ! caspase regulator activity GO:0043028 28 28 0,000 0,02999137 0,03831813 ! ensheathment of neurons GO:0007272 29 28 0,000 0,02999137 0,03830443 GO:0008366|axon ensheathment, ! DNA polymerase activity GO:0034061 29 28 0,000 0,02999137 0,03829073 ! calcium-mediated signaling GO:0019722 28 28 0,000 0,02999137 0,03827705 ! neurotransmitter secretion GO:0007269 29 28 0,000 0,02999137 0,03826337 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 28 28 0,000 0,02999137 0,03824971 ! glycogen metabolic process GO:0005977 29 28 0,000 0,02999137 0,03823605 ! RNA helicase activity GO:0003724 28 28 0,000 0,02999137 0,0382224 ! Rho GTPase activator activity GO:0005100 32 28 0,000 0,02999137 0,03820877 ! symbiosis, encompassing mutualism through parasitism GO:0044403 32 28 0,000 0,02999137 0,03819514 ! transferase activity, transferring nitrogenous groups GO:0016769 30 29 0,000 0,03104673 0,03952509 ! spliceosomal snRNP biogenesis GO:0000387 30 29 0,000 0,03104673 0,039511 ! odontogenesis of dentine-containing tooth GO:0042475 30 29 0,000 0,03104673 0,03949693 ! scavenger receptor activity GO:0005044 30 29 0,000 0,03104673 0,03948286 ! mesoderm morphogenesis GO:0048332 30 29 0,000 0,03104673 0,0394688 ! male gonad development GO:0008584 29 29 0,000 0,03104673 0,03945476 ! response to organic cyclic substance GO:0014070 31 29 0,000 0,03104673 0,03944072 ! negative regulation of MAP kinase activity GO:0043407 30 29 0,000 0,03104673 0,0394267 ! sterol biosynthetic process GO:0016126 30 29 0,000 0,03104673 0,03941268 ! endocytic vesicle GO:0030139 29 29 0,000 0,03104673 0,03939868 ! Rho GTPase binding GO:0017048 32 29 0,000 0,03104673 0,03938468 ! serine family amino acid metabolic process GO:0009069 30 29 0,000 0,03104673 0,03937069 ! fatty acid catabolic process GO:0009062 30 29 0,000 0,03104673 0,03935672 ! regulation of calcium ion transport GO:0051924 32 29 0,000 0,03104673 0,03934275 ! negative regulation of protein polymerization GO:0032272 29 29 0,000 0,03104673 0,03932879 ! glucan metabolic process GO:0044042 30 29 0,000 0,03104673 0,03931485 GO:0006073|cellular glucan metabolic process, ! regulation of synaptic plasticity GO:0048167 29 29 0,000 0,03104673 0,03930091 ! proteoglycan metabolic process GO:0006029 30 29 0,000 0,03104673 0,03928699 ! xenobiotic metabolic process GO:0006805 29 29 0,000 0,03104673 0,03927307 ! negative regulation of response to external stimulus GO:0032102 29 29 0,000 0,03104673 0,03925916 ! positive regulation of T cell proliferation GO:0042102 33 29 0,000 0,03104673 0,03924526 ! steroid dehydrogenase activity GO:0016229 29 29 0,000 0,03104673 0,03923138 ! regulation of protein import into nucleus GO:0042306 30 29 0,000 0,03104673 0,0392175 ! clathrin coated vesicle membrane GO:0030665 32 29 0,000 0,03104673 0,03920363 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 30 29 0,000 0,03104673 0,03918977 ! cytosolic small ribosomal subunit GO:0022627 29 29 0,000 0,03104673 0,03917593 ! detection of visible light GO:0009584 29 29 0,000 0,03104673 0,03916209 ! tumor necrosis factor receptor superfamily binding GO:0032813 29 29 0,000 0,03104673 0,03914826 ! acetylglucosaminyltransferase activity GO:0008375 30 29 0,000 0,03104673 0,03913444 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,03104673 0,03912063 ! hormone binding GO:0042562 30 30 0,000 0,03210101 0,04043482 ! negative regulation of DNA metabolic process GO:0051053 34 30 0,000 0,03210101 0,04042056 ! inner ear morphogenesis GO:0042472 31 30 0,000 0,03210101 0,04040632 ! GPI anchor biosynthetic process GO:0006506 32 30 0,000 0,03210101 0,04039208 ! acrosomal vesicle GO:0001669 32 30 0,000 0,03210101 0,04037785 ! negative regulation of DNA binding GO:0043392 31 30 0,000 0,03210101 0,04036363 ! triglyceride metabolic process GO:0006641 31 30 0,000 0,03210101 0,04034943 ! erythrocyte differentiation GO:0030218 32 30 0,000 0,03210101 0,04033523 ! glutamate receptor activity GO:0008066 33 30 0,000 0,03210101 0,04032104 ! ceramide metabolic process GO:0006672 30 30 0,000 0,03210101 0,04030686 ! cell fate specification GO:0001708 31 30 0,000 0,03210101 0,0402927 ! hexose biosynthetic process GO:0019319 32 30 0,000 0,03210101 0,04027854 ! PDZ domain binding GO:0030165 32 30 0,000 0,03210101 0,04026439 ! AP-type membrane coat adaptor complex GO:0030119 31 30 0,000 0,03210101 0,04025025 GO:0030131|clathrin adaptor complex, ! embryonic epithelial tube formation GO:0001838 32 30 0,000 0,03210101 0,04023613 ! negative regulation of cell activation GO:0050866 31 30 0,000 0,03210101 0,04022201 ! negative regulation of protein transport GO:0051224 30 30 0,000 0,03210101 0,0402079 ! negative regulation of protein complex assembly GO:0031333 30 30 0,000 0,03210101 0,0401938 ! regulation of JAK-STAT cascade GO:0046425 32 30 0,000 0,03210101 0,04017971 ! drug binding GO:0008144 30 30 0,000 0,03210101 0,04016563 ! multicellular organismal macromolecule metabolic process GO:0044259 30 30 0,000 0,03210101 0,04015157 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 33 30 0,000 0,03210101 0,04013751 ! regulation of systemic arterial blood pressure GO:0003073 32 30 0,000 0,03210101 0,04012346 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 31 30 0,000 0,03210101 0,04010942 ! aminopeptidase activity GO:0004177 32 30 0,000 0,03210101 0,04009539 ! detection of light stimulus GO:0009583 30 30 0,000 0,03210101 0,04008137 ! L-amino acid transmembrane transporter activity GO:0015179 30 30 0,000 0,03210101 0,04006736 ! cysteine-type endopeptidase inhibitor activity GO:0004869 32 30 0,000 0,03210101 0,04005336 ! meiosis I GO:0007127 31 31 0,000 0,03315422 0,04135303 ! negative regulation of cell adhesion GO:0007162 33 31 0,000 0,03315422 0,04133859 ! striated muscle cell differentiation GO:0051146 31 31 0,000 0,03315422 0,04132416 ! GPI anchor metabolic process GO:0006505 33 31 0,000 0,03315422 0,04130975 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,03315422 0,04129534 ! spliceosome assembly GO:0000245 32 31 0,000 0,03315422 0,04128094 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 32 31 0,000 0,03315422 0,04126655 GO:0004601|peroxidase activity, ! unsaturated fatty acid biosynthetic process GO:0006636 32 31 0,000 0,03315422 0,04125217 ! NAD or NADH binding GO:0051287 31 31 0,000 0,03315422 0,0412378 ! positive regulation of neurogenesis GO:0050769 32 31 0,000 0,03315422 0,04122344 ! cyclic nucleotide metabolic process GO:0009187 31 31 0,000 0,03315422 0,0412091 ! nucleotide catabolic process GO:0009166 32 31 0,000 0,03315422 0,04119476 ! replication fork GO:0005657 32 31 0,000 0,03315422 0,04118043 ! placenta development GO:0001890 31 31 0,000 0,03315422 0,04116611 ! regulation of pH GO:0006885 31 31 0,000 0,03315422 0,0411518 ! protein methyltransferase activity GO:0008276 36 31 0,000 0,03315422 0,0411375 ! acute-phase response GO:0006953 32 31 0,000 0,03315422 0,04112321 ! peptide transport GO:0015833 32 31 0,000 0,03315422 0,04110893 ! respiratory gaseous exchange GO:0007585 32 31 0,000 0,03315422 0,04109467 ! DNA integrity checkpoint GO:0031570 34 31 0,000 0,03315422 0,04108041 ! Golgi-associated vesicle membrane GO:0030660 34 31 0,000 0,03315422 0,04106616 ! regulation of protein stability GO:0031647 32 31 0,000 0,03315422 0,04105192 ! sarcolemma GO:0042383 33 31 0,000 0,03315422 0,04103769 ! vesicle localization GO:0051648 32 31 0,000 0,03315422 0,04102347 ! microtubule organizing center part GO:0044450 34 31 0,000 0,03315422 0,04100926 ! response to hydrogen peroxide GO:0042542 34 32 0,000 0,03420636 0,04229602 ! DNA helicase activity GO:0003678 34 32 0,000 0,03420636 0,04228138 ! NADP or NADPH binding GO:0050661 33 32 0,000 0,03420636 0,04226675 ! pigment biosynthetic process GO:0046148 34 32 0,000 0,03420636 0,04225213 ! purinergic nucleotide receptor activity GO:0001614 34 32 0,000 0,03420636 0,04223752 GO:0016502|nucleotide receptor activity, ! female gonad development GO:0008585 32 32 0,000 0,03420636 0,04222292 ! late endosome membrane GO:0031902 32 32 0,000 0,03420636 0,04220833 ! positive regulation of cell development GO:0010720 33 32 0,000 0,03420636 0,04219375 ! regulation of Wnt receptor signaling pathway GO:0030111 35 32 0,000 0,03420636 0,04217918 ! hindbrain development GO:0030902 35 32 0,000 0,03420636 0,04216462 ! aerobic respiration GO:0009060 32 32 0,000 0,03420636 0,04215007 ! positive regulation of catabolic process GO:0009896 34 32 0,000 0,03420636 0,04213553 ! regulation of muscle development GO:0048634 33 32 0,000 0,03420636 0,042121 GO:0016202|regulation of striated muscle tissue development, ! cation:sugar symporter activity GO:0005402 32 32 0,000 0,03420636 0,04210648 GO:0005351|sugar:hydrogen symporter activity, ! sphingoid metabolic process GO:0046519 32 32 0,000 0,03420636 0,04209197 ! response to ionizing radiation GO:0010212 33 32 0,000 0,03420636 0,04207747 ! flagellum GO:0019861 32 32 0,000 0,03420636 0,04206298 ! regulation of lymphocyte mediated immunity GO:0002706 36 32 0,000 0,03420636 0,0420485 ! I band GO:0031674 35 32 0,000 0,03420636 0,04203403 ! JAK-STAT cascade GO:0007259 34 32 0,000 0,03420636 0,04201957 ! cellular response to insulin stimulus GO:0032869 37 32 0,000 0,03420636 0,04200512 ! adult locomotory behavior GO:0008344 33 32 0,000 0,03420636 0,04199069 ! pyrimidine nucleotide metabolic process GO:0006220 37 32 0,000 0,03420636 0,04197626 ! positive regulation of transcription factor activity GO:0051091 34 33 0,000 0,03525742 0,0432512 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of secretion GO:0051048 34 33 0,000 0,03525742 0,04323635 ! establishment or maintenance of cell polarity GO:0007163 33 33 0,000 0,03525742 0,0432215 ! platelet alpha granule lumen GO:0031093 34 33 0,000 0,03525742 0,04320667 ! negative regulation of binding GO:0051100 34 33 0,000 0,03525742 0,04319185 ! protein targeting to membrane GO:0006612 35 33 0,000 0,03525742 0,04317704 ! vesicle coat GO:0030120 36 33 0,000 0,03525742 0,04316224 ! endoribonuclease activity GO:0004521 34 33 0,000 0,03525742 0,04314744 ! eye morphogenesis GO:0048592 38 33 0,000 0,03525742 0,04313266 ! embryonic organ development GO:0048568 36 33 0,000 0,03525742 0,04311789 ! monosaccharide biosynthetic process GO:0046364 35 33 0,000 0,03525742 0,04310313 ! glial cell differentiation GO:0010001 33 33 0,000 0,03525742 0,04308838 ! cell junction organization GO:0034330 35 33 0,000 0,03525742 0,04307364 ! tissue remodeling GO:0048771 35 33 0,000 0,03525742 0,04305891 ! segmentation GO:0035282 34 33 0,000 0,03525742 0,04304419 ! positive regulation of gene-specific transcription GO:0043193 34 33 0,000 0,03525742 0,04302947 ! energy coupled proton transport, down electrochemical gradient GO:0015985 33 33 0,000 0,03525742 0,04301477 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 35 33 0,000 0,03525742 0,04300008 ! hormone biosynthetic process GO:0042446 33 33 0,000 0,03525742 0,0429854 ! O-acyltransferase activity GO:0008374 33 33 0,000 0,03525742 0,04297073 ! response to xenobiotic stimulus GO:0009410 33 33 0,000 0,03525742 0,04295607 ! cellular amide metabolic process GO:0043603 34 34 0,000 0,03630741 0,04422024 ! sugar transmembrane transporter activity GO:0051119 34 34 0,000 0,03630741 0,04420517 GO:0015144|carbohydrate transmembrane transporter activity, ! neural tube development GO:0021915 36 34 0,000 0,03630741 0,0441901 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 34 0,000 0,03630741 0,04417504 ! neutral lipid metabolic process GO:0006638 35 34 0,000 0,03630741 0,04416 GO:0006639|acylglycerol metabolic process, ! lipid homeostasis GO:0055088 34 34 0,000 0,03630741 0,04414496 ! telencephalon development GO:0021537 34 34 0,000 0,03630741 0,04412994 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 35 34 0,000 0,03630741 0,04411492 ! integral to Golgi membrane GO:0030173 34 34 0,000 0,03630741 0,04409992 ! intramolecular oxidoreductase activity GO:0016860 35 34 0,000 0,03630741 0,04408492 ! collagen GO:0005581 35 34 0,000 0,03630741 0,04406994 ! development of primary female sexual characteristics GO:0046545 34 34 0,000 0,03630741 0,04405496 GO:0046660|female sex differentiation, ! DNA-directed RNA polymerase activity GO:0003899 35 34 0,000 0,03630741 0,04404 GO:0034062|RNA polymerase activity, ! leukocyte chemotaxis GO:0030595 35 34 0,000 0,03630741 0,04402504 GO:0060326|cell chemotaxis, ! sodium channel activity GO:0005272 36 34 0,000 0,03630741 0,0440101 ! spermatid development GO:0007286 34 34 0,000 0,03630741 0,04399516 ! BMP signaling pathway GO:0030509 35 34 0,000 0,03630741 0,04398024 ! specific RNA polymerase II transcription factor activity GO:0003704 35 34 0,000 0,03630741 0,04396533 ! positive regulation of DNA metabolic process GO:0051054 40 35 0,000 0,03735632 0,04522015 ! mitotic cell cycle checkpoint GO:0007093 35 35 0,000 0,03735632 0,04520482 ! regulation of intracellular protein transport GO:0033157 37 35 0,000 0,03735632 0,04518951 ! vesicle lumen GO:0031983 37 35 0,000 0,03735632 0,04517421 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! metanephros development GO:0001656 35 35 0,000 0,03735632 0,04515891 ! regulation of action potential in neuron GO:0019228 38 35 0,000 0,03735632 0,04514363 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 39 35 0,000 0,03735632 0,04512836 ! cytokine production GO:0001816 35 35 0,000 0,03735632 0,0451131 ! carbon-carbon lyase activity GO:0016830 35 35 0,000 0,03735632 0,04509785 ! embryonic pattern specification GO:0009880 36 35 0,000 0,03735632 0,04508261 ! regulation of metal ion transport GO:0010959 38 35 0,000 0,03735632 0,04506738 ! energy reserve metabolic process GO:0006112 36 35 0,000 0,03735632 0,04505216 ! phagocytosis GO:0006909 37 35 0,000 0,03735632 0,04503695 ! ion transmembrane transport GO:0034220 35 35 0,000 0,03735632 0,04502175 ! neuropeptide receptor activity GO:0008188 35 35 0,000 0,03735632 0,04500656 ! oxygen binding GO:0019825 36 35 0,000 0,03735632 0,04499138 ! regulation of leukocyte mediated immunity GO:0002703 39 35 0,000 0,03735632 0,04497621 ! erythrocyte homeostasis GO:0034101 37 35 0,000 0,03735632 0,04496105 ! peripheral nervous system development GO:0007422 37 35 0,000 0,03735632 0,0449459 ! female gamete generation GO:0007292 38 35 0,000 0,03735632 0,04493076 ! polyol metabolic process GO:0019751 36 35 0,000 0,03735632 0,04491563 ! negative regulation of adenylate cyclase activity GO:0007194 38 36 0,000 0,03840417 0,04615998 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of hormone secretion GO:0046883 38 36 0,000 0,03840417 0,04614445 ! monocarboxylic acid binding GO:0033293 37 36 0,000 0,03840417 0,04612893 ! polysaccharide biosynthetic process GO:0000271 36 36 0,000 0,03840417 0,04611341 ! regulation of axonogenesis GO:0050770 39 36 0,000 0,03840417 0,04609791 ! glycerol ether metabolic process GO:0006662 37 36 0,000 0,03840417 0,04608242 ! regulation of proteolysis GO:0030162 37 36 0,000 0,03840417 0,04606694 ! integral to endoplasmic reticulum membrane GO:0030176 36 36 0,000 0,03840417 0,04605148 ! regulation of adaptive immune response GO:0002819 40 36 0,000 0,03840417 0,04603602 ! oxidoreduction coenzyme metabolic process GO:0006733 37 36 0,000 0,03840417 0,04602057 ! isoprenoid metabolic process GO:0006720 37 36 0,000 0,03840417 0,04600513 ! spermatid differentiation GO:0048515 36 36 0,000 0,03840417 0,0459897 ! phosphoinositide biosynthetic process GO:0046489 38 36 0,000 0,03840417 0,04597429 ! ER to Golgi vesicle-mediated transport GO:0006888 36 36 0,000 0,03840417 0,04595888 ! condensed chromosome kinetochore GO:0000777 37 36 0,000 0,03840417 0,04594348 ! neuropeptide binding GO:0042923 36 36 0,000 0,03840417 0,0459281 ! organic anion transport GO:0015711 37 36 0,000 0,03840417 0,04591272 ! carbohydrate homeostasis GO:0033500 38 36 0,000 0,03840417 0,04589735 GO:0042593|glucose homeostasis, ! complement activation GO:0006956 39 36 0,000 0,03840417 0,045882 ! antigen binding GO:0003823 36 36 0,000 0,03840417 0,04586665 ! extrinsic to plasma membrane GO:0019897 36 36 0,000 0,03840417 0,04585132 ! cytokinesis GO:0000910 40 36 0,000 0,03840417 0,04583599 ! coated pit GO:0005905 42 36 0,000 0,03840417 0,04582068 ! protein amino acid N-linked glycosylation GO:0006487 40 37 0,000 0,03945095 0,04705389 ! ribonucleoside metabolic process GO:0009119 43 37 0,000 0,03945095 0,04703818 ! DNA-dependent ATPase activity GO:0008094 39 37 0,000 0,03945095 0,04702248 ! regulation of T cell differentiation GO:0045580 41 37 0,000 0,03945095 0,04700679 ! biopolymer methylation GO:0043414 42 37 0,000 0,03945095 0,04699111 ! intrinsic to Golgi membrane GO:0031228 37 37 0,000 0,03945095 0,04697544 ! protein homooligomerization GO:0051260 38 37 0,000 0,03945095 0,04695978 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 38 37 0,000 0,03945095 0,04694413 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 41 37 0,000 0,03945095 0,04692849 ! regulation of T cell proliferation GO:0042129 41 37 0,000 0,03945095 0,04691287 ! multicellular organismal metabolic process GO:0044236 38 37 0,000 0,03945095 0,04689725 ! amino acid binding GO:0016597 40 37 0,000 0,03945095 0,04688164 ! maintenance of protein location GO:0045185 38 37 0,000 0,03945095 0,04686605 ! maintenance of location in cell GO:0051651 38 37 0,000 0,03945095 0,04685046 ! solute:hydrogen symporter activity GO:0015295 37 37 0,000 0,03945095 0,04683489 ! proton-transporting two-sector ATPase complex GO:0016469 37 37 0,000 0,03945095 0,04681932 ! ear morphogenesis GO:0042471 39 38 0,000 0,04049666 0,04804437 ! odontogenesis GO:0042476 40 38 0,000 0,04049666 0,04802842 ! organic ether metabolic process GO:0018904 39 38 0,000 0,04049666 0,04801247 ! alcohol biosynthetic process GO:0046165 40 38 0,000 0,04049666 0,04799654 ! monovalent inorganic cation homeostasis GO:0055067 39 38 0,000 0,04049666 0,04798061 ! positive regulation of DNA binding GO:0043388 39 38 0,000 0,04049666 0,0479647 ! B cell differentiation GO:0030183 40 38 0,000 0,04049666 0,04794879 ! clathrin coat GO:0030118 43 38 0,000 0,04049666 0,0479329 ! regulation of endocytosis GO:0030100 39 38 0,000 0,04049666 0,04791702 ! dorsal/ventral pattern formation GO:0009953 38 38 0,000 0,04049666 0,04790115 ! cell growth GO:0016049 40 38 0,000 0,04049666 0,04788529 ! positive regulation of defense response GO:0031349 38 38 0,000 0,04049666 0,04786943 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 38 0,000 0,04049666 0,04785359 ! condensed chromosome, centromeric region GO:0000779 39 38 0,000 0,04049666 0,04783776 ! learning GO:0007612 42 38 0,000 0,04049666 0,04782195 ! negative regulation of protein complex disassembly GO:0043242 40 38 0,000 0,04049666 0,04780614 ! monocarboxylic acid transport GO:0015718 39 38 0,000 0,04049666 0,04779034 ! endosome transport GO:0016197 40 38 0,000 0,04049666 0,04777455 ! hormone-mediated signaling GO:0009755 39 38 0,000 0,04049666 0,04775877 ! N-methyltransferase activity GO:0008170 42 38 0,000 0,04049666 0,04774301 ! cytosolic large ribosomal subunit GO:0022625 38 38 0,000 0,04049666 0,04772725 ! pigment metabolic process GO:0042440 42 38 0,000 0,04049666 0,0477115 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 38 38 0,000 0,04049666 0,04769577 ! regulation of nucleocytoplasmic transport GO:0046822 41 39 0,000 0,0415413 0,04890998 ! Notch signaling pathway GO:0007219 41 39 0,000 0,0415413 0,04889386 ! induction of apoptosis by extracellular signals GO:0008624 39 39 0,000 0,0415413 0,04887775 ! keratin filament GO:0045095 41 39 0,000 0,0415413 0,04886165 ! ER-Golgi intermediate compartment GO:0005793 42 39 0,000 0,0415413 0,04884556 ! peroxisomal membrane GO:0005778 40 39 0,000 0,0415413 0,04882949 GO:0031903|microbody membrane, ! mitochondrial respiratory chain complex I GO:0005747 39 39 0,000 0,0415413 0,04881342 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! actin filament binding GO:0051015 39 39 0,000 0,0415413 0,04879736 ! regulation of protein secretion GO:0050708 41 39 0,000 0,0415413 0,04878131 ! cis-trans isomerase activity GO:0016859 39 39 0,000 0,0415413 0,04876528 ! regulation of cell morphogenesis involved in differentiation GO:0010769 42 39 0,000 0,0415413 0,04874925 ! viral infectious cycle GO:0019058 39 39 0,000 0,0415413 0,04873324 ! mammary gland development GO:0030879 41 39 0,000 0,0415413 0,04871723 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 39 0,000 0,0415413 0,04870124 ! amine receptor activity GO:0008227 41 39 0,000 0,0415413 0,04868526 ! positive regulation of response to external stimulus GO:0032103 39 39 0,000 0,0415413 0,04866928 ! monosaccharide binding GO:0048029 39 39 0,000 0,0415413 0,04865332 ! NADH dehydrogenase (ubiquinone) activity GO:0008137 39 39 0,000 0,0415413 0,04863737 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! phosphotransferase activity, phosphate group as acceptor GO:0016776 44 40 0,000 0,04258487 0,04984287 ! response to estrogen stimulus GO:0043627 41 40 0,000 0,04258487 0,04982654 ! peptide metabolic process GO:0006518 41 40 0,000 0,04258487 0,04981021 ! regulation of Rab protein signal transduction GO:0032483 41 40 0,000 0,04258487 0,0497939 GO:0032313|regulation of Rab GTPase activity, ! T cell differentiation GO:0030217 45 40 0,000 0,04258487 0,04977761 ! regulation of multicellular organism growth GO:0040014 42 40 0,000 0,04258487 0,04976132 ! regulation of gene expression, epigenetic GO:0040029 43 40 0,000 0,04258487 0,04974504 ! neuron migration GO:0001764 42 40 0,000 0,04258487 0,04972877 ! inositol or phosphatidylinositol kinase activity GO:0004428 42 40 0,000 0,04258487 0,04971252 ! structural constituent of muscle GO:0008307 43 40 0,000 0,04258487 0,04969627 ! gliogenesis GO:0042063 40 40 0,000 0,04258487 0,04968003 ! feeding behavior GO:0007631 40 40 0,000 0,04258487 0,04966381 ! positive regulation of cytokine biosynthetic process GO:0042108 41 40 0,000 0,04258487 0,0496476 ! sulfur compound biosynthetic process GO:0044272 41 40 0,000 0,04258487 0,04963139 ! inorganic anion transmembrane transporter activity GO:0015103 42 40 0,000 0,04258487 0,0496152 ! chromatin remodeling GO:0006338 43 40 0,000 0,04258487 0,04959902 ! activation of adenylate cyclase activity GO:0007190 42 41 0,000 0,04362738 0,05079667 ! positive regulation of binding GO:0051099 42 41 0,000 0,04362738 0,05078011 ! response to reactive oxygen species GO:0000302 43 41 0,000 0,04362738 0,05076357 ! solute:sodium symporter activity GO:0015370 41 41 0,000 0,04362738 0,05074703 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 44 41 0,000 0,04362738 0,05073051 GO:0046328|regulation of JNK cascade, ! mesenchymal cell development GO:0014031 43 41 0,000 0,04362738 0,05071399 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! heterocycle biosynthetic process GO:0018130 43 41 0,000 0,04362738 0,05069749 ! exonuclease activity GO:0004527 42 41 0,000 0,04362738 0,050681 ! regulation of myeloid cell differentiation GO:0045637 43 41 0,000 0,04362738 0,05066452 ! positive regulation of cytokine production GO:0001819 42 41 0,000 0,04362738 0,05064805 ! hydro-lyase activity GO:0016836 44 41 0,000 0,04362738 0,05063159 ! positive regulation of protein transport GO:0051222 44 41 0,000 0,04362738 0,05061514 ! receptor-mediated endocytosis GO:0006898 43 41 0,000 0,04362738 0,0505987 ! regulation of neuron projection development GO:0010975 44 41 0,000 0,04362738 0,05058227 ! metal cluster binding GO:0051540 43 41 0,000 0,04362738 0,05056585 GO:0051536|iron-sulfur cluster binding, ! embryonic skeletal system morphogenesis GO:0048704 42 41 0,000 0,04362738 0,05054944 ! development of primary male sexual characteristics GO:0046546 41 41 0,000 0,04362738 0,05053305 ! double-strand break repair GO:0006302 41 41 0,000 0,04362738 0,05051666 ! Rab GTPase activator activity GO:0005097 42 41 0,000 0,04362738 0,05050029 ! RNA catabolic process GO:0006401 44 42 0,000 0,04466883 0,05168904 ! organellar ribosome GO:0000313 43 42 0,000 0,04466883 0,0516723 GO:0005761|mitochondrial ribosome, ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 44 42 0,000 0,04466883 0,05165557 ! damaged DNA binding GO:0003684 42 42 0,000 0,04466883 0,05163884 ! MHC protein complex GO:0042611 42 42 0,000 0,04466883 0,05162213 ! regulation of epithelial cell proliferation GO:0050678 44 42 0,000 0,04466883 0,05160543 ! negative regulation of cell migration GO:0030336 44 42 0,000 0,04466883 0,05158874 ! icosanoid metabolic process GO:0006690 43 42 0,000 0,04466883 0,05157206 ! chemokine activity GO:0008009 42 42 0,000 0,04466883 0,05155539 ! ruffle GO:0001726 44 42 0,000 0,04466883 0,05153874 ! pigmentation GO:0043473 46 42 0,000 0,04466883 0,05152209 ! developmental growth GO:0048589 42 42 0,000 0,04466883 0,05150545 ! methylation GO:0032259 47 42 0,000 0,04466883 0,05148883 ! glycolysis GO:0006096 42 42 0,000 0,04466883 0,05147221 ! morphogenesis of embryonic epithelium GO:0016331 44 42 0,000 0,04466883 0,05145561 ! regulation of tube size GO:0035150 44 42 0,000 0,04466883 0,05143902 GO:0050880|regulation of blood vessel size, ! branching morphogenesis of a tube GO:0048754 43 42 0,000 0,04466883 0,05142243 ! general RNA polymerase II transcription factor activity GO:0016251 44 42 0,000 0,04466883 0,05140586 ! cellular amino acid derivative biosynthetic process GO:0042398 43 42 0,000 0,04466883 0,0513893 ! positive regulation of adenylate cyclase activity GO:0045762 44 43 0,000 0,04570921 0,05256927 ! transferase activity, transferring pentosyl groups GO:0016763 45 43 0,000 0,04570921 0,05255235 ! epithelial cell differentiation GO:0030855 45 43 0,000 0,04570921 0,05253544 ! detection of stimulus involved in sensory perception GO:0050906 43 43 0,000 0,04570921 0,05251853 ! sulfotransferase activity GO:0008146 44 43 0,000 0,04570921 0,05250164 ! cellular polysaccharide metabolic process GO:0044264 44 43 0,000 0,04570921 0,05248476 ! channel regulator activity GO:0016247 46 43 0,000 0,04570921 0,05246789 ! histone modification GO:0016570 44 43 0,000 0,04570921 0,05245103 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 45 43 0,000 0,04570921 0,05243418 ! synaptosome GO:0019717 47 43 0,000 0,04570921 0,05241734 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 45 44 0,000 0,04674853 0,05359198 ! platelet alpha granule GO:0031091 46 44 0,000 0,04674853 0,05357478 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 44 44 0,000 0,04674853 0,05355759 ! regulation of ossification GO:0030278 48 44 0,000 0,04674853 0,05354041 ! cell recognition GO:0008037 46 44 0,000 0,04674853 0,05352325 ! positive regulation of cyclase activity GO:0031281 45 44 0,000 0,04674853 0,05350609 ! regulation of lymphocyte differentiation GO:0045619 48 44 0,000 0,04674853 0,05348895 ! regulation of actin filament polymerization GO:0030833 45 44 0,000 0,04674853 0,05347182 ! regulation of protein complex disassembly GO:0043244 46 44 0,000 0,04674853 0,05345469 ! regulation of ion transport GO:0043269 47 44 0,000 0,04674853 0,05343758 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 50 44 0,000 0,04674853 0,05342048 ! inner ear development GO:0048839 46 44 0,000 0,04674853 0,05340339 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 48 44 0,000 0,04674853 0,05338632 ! amino acid transmembrane transporter activity GO:0015171 44 44 0,000 0,04674853 0,05336925 ! negative regulation of immune system process GO:0002683 49 44 0,000 0,04674853 0,05335219 ! chemokine receptor binding GO:0042379 44 44 0,000 0,04674853 0,05333515 ! regulation of action potential GO:0001508 50 45 0,000 0,04778679 0,05450228 ! regulation of gene-specific transcription GO:0032583 47 45 0,000 0,04778679 0,05448488 ! cellular amino acid biosynthetic process GO:0008652 47 45 0,000 0,04778679 0,05446749 ! nucleoside monophosphate biosynthetic process GO:0009124 50 45 0,000 0,04778679 0,05445011 ! positive regulation of lyase activity GO:0051349 46 45 0,000 0,04778679 0,05443274 ! regulation of neuron apoptosis GO:0043523 45 45 0,000 0,04778679 0,05441538 ! excretion GO:0007588 46 45 0,000 0,04778679 0,05439803 ! protein phosphatase regulator activity GO:0019888 49 45 0,000 0,04778679 0,0543807 ! JNK cascade GO:0007254 45 45 0,000 0,04778679 0,05436337 ! SH3/SH2 adaptor activity GO:0005070 48 45 0,000 0,04778679 0,05434606 ! regulation of cell shape GO:0008360 46 45 0,000 0,04778679 0,05432876 ! epithelial tube morphogenesis GO:0060562 47 45 0,000 0,04778679 0,05431147 ! microbody part GO:0044438 46 45 0,000 0,04778679 0,05429419 GO:0044439|peroxisomal part, ! auxiliary transport protein activity GO:0015457 50 46 0,000 0,04882399 0,05545498 ! ATP synthesis coupled electron transport GO:0042773 46 46 0,000 0,04882399 0,05543735 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! microtubule binding GO:0008017 49 46 0,000 0,04882399 0,05541973 ! regulation of inflammatory response GO:0050727 46 46 0,000 0,04882399 0,05540212 ! transport vesicle GO:0030133 49 46 0,000 0,04882399 0,05538452 ! glutamine family amino acid metabolic process GO:0009064 49 46 0,000 0,04882399 0,05536693 ! synapse organization GO:0050808 51 46 0,000 0,04882399 0,05534936 ! striated muscle contraction GO:0006941 49 46 0,000 0,04882399 0,05533179 ! unsaturated fatty acid metabolic process GO:0033559 47 46 0,000 0,04882399 0,05531424 ! antioxidant activity GO:0016209 47 46 0,000 0,04882399 0,05529669 ! aging GO:0007568 48 46 0,000 0,04882399 0,05527916 ! male sex differentiation GO:0046661 46 46 0,000 0,04882399 0,05526164 ! coated vesicle membrane GO:0030662 49 46 0,000 0,04882399 0,05524413 ! covalent chromatin modification GO:0016569 47 46 0,000 0,04882399 0,05522663 ! RNA elongation from RNA polymerase II promoter GO:0006368 48 46 0,000 0,04882399 0,05520914 ! protein amino acid lipidation GO:0006497 50 47 0,000 0,04986013 0,05636294 ! stress-activated protein kinase signaling pathway GO:0031098 47 47 0,000 0,04986013 0,0563451 ! carbohydrate transport GO:0008643 47 47 0,000 0,04986013 0,05632728 ! proteasome complex GO:0000502 48 47 0,000 0,04986013 0,05630946 ! immunoglobulin mediated immune response GO:0016064 50 47 0,000 0,04986013 0,05629166 ! phosphatase regulator activity GO:0019208 51 47 0,000 0,04986013 0,05627387 ! vesicle organization GO:0016050 50 47 0,000 0,04986013 0,05625609 ! vascular process in circulatory system GO:0003018 49 47 0,000 0,04986013 0,05623832 ! cell cortex part GO:0044448 51 47 0,000 0,04986013 0,05622056 ! lipid modification GO:0030258 49 48 0,000 0,05089521 0,05736957 ! cytokine-mediated signaling pathway GO:0019221 49 48 0,000 0,05089521 0,05735147 ! morphogenesis of a branching structure GO:0001763 49 48 0,000 0,05089521 0,05733337 ! mitochondrial transport GO:0006839 49 48 0,000 0,05089521 0,05731529 ! viral reproductive process GO:0022415 52 48 0,000 0,05089521 0,05729723 ! leukocyte migration GO:0050900 49 48 0,000 0,05089521 0,05727917 ! neuromuscular process GO:0050905 49 48 0,000 0,05089521 0,05726112 ! gastrulation GO:0007369 50 48 0,000 0,05089521 0,05724309 ! detection of abiotic stimulus GO:0009582 48 48 0,000 0,05089521 0,05722506 ! heterocycle catabolic process GO:0046700 53 48 0,000 0,05089521 0,05720705 ! B cell mediated immunity GO:0019724 51 48 0,000 0,05089521 0,05718905 ! transferase activity, transferring sulfur-containing groups GO:0016782 50 49 0,000 0,05192923 0,05833259 ! single-stranded DNA binding GO:0003697 49 49 0,000 0,05192923 0,05831424 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 54 49 0,000 0,05192923 0,05829591 ! intrinsic to endoplasmic reticulum membrane GO:0031227 50 49 0,000 0,05192923 0,05827759 ! ribonuclease activity GO:0004540 50 49 0,000 0,05192923 0,05825928 ! water-soluble vitamin metabolic process GO:0006767 50 49 0,000 0,05192923 0,05824099 ! negative regulation of cell motion GO:0051271 51 49 0,000 0,05192923 0,0582227 ! nucleosome GO:0000786 49 49 0,000 0,05192923 0,05820442 ! kinetochore GO:0000776 50 49 0,000 0,05192923 0,05818616 ! membrane fusion GO:0006944 51 49 0,000 0,05192923 0,05816791 ! endocrine system development GO:0035270 49 49 0,000 0,05192923 0,05814967 ! RNA elongation GO:0006354 51 49 0,000 0,05192923 0,05813144 ! glycosaminoglycan metabolic process GO:0030203 53 50 0,000 0,0529622 0,0592692 ! regulation of actin polymerization or depolymerization GO:0008064 51 50 0,000 0,0529622 0,05925063 ! basement membrane GO:0005604 51 50 0,000 0,0529622 0,05923208 ! regulation of intracellular transport GO:0032386 52 50 0,000 0,0529622 0,05921353 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,0529622 0,059195 ! maintenance of location GO:0051235 51 50 0,000 0,0529622 0,05917648 ! cell redox homeostasis GO:0045454 51 50 0,000 0,0529622 0,05915797 ! integrin binding GO:0005178 53 50 0,000 0,0529622 0,05913947 ! regulation of DNA replication GO:0006275 56 50 0,000 0,0529622 0,05912098 ! amino acid activation GO:0043038 50 50 0,000 0,0529622 0,05910251 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! establishment of organelle localization GO:0051656 53 50 0,000 0,0529622 0,05908404 ! regulation of bone remodeling GO:0046850 55 51 0,000 0,05399412 0,06021642 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 52 51 0,000 0,05399412 0,06019762 ! late endosome GO:0005770 51 51 0,000 0,05399412 0,06017883 ! ligase activity, forming carbon-oxygen bonds GO:0016875 51 51 0,000 0,05399412 0,06016006 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! negative regulation of response to stimulus GO:0048585 55 51 0,000 0,05399412 0,06014129 ! carbon-oxygen lyase activity GO:0016835 54 51 0,000 0,05399412 0,06012254 ! skeletal muscle fiber development GO:0048741 54 51 0,000 0,05399412 0,0601038 ! lipoprotein biosynthetic process GO:0042158 54 51 0,000 0,05399412 0,06008507 ! heart morphogenesis GO:0003007 54 51 0,000 0,05399412 0,06006635 ! antiporter activity GO:0015297 52 51 0,000 0,05399412 0,06004764 ! respiratory electron transport chain GO:0022904 52 52 0,000 0,05502497 0,06117503 ! positive regulation of cell migration GO:0030335 55 52 0,000 0,05502497 0,06115599 ! Golgi-associated vesicle GO:0005798 55 52 0,000 0,05502497 0,06113696 ! sphingolipid metabolic process GO:0006665 53 52 0,000 0,05502497 0,06111794 ! cell maturation GO:0048469 55 52 0,000 0,05502497 0,06109894 ! regulation of protein polymerization GO:0032271 53 52 0,000 0,05502497 0,06107994 ! regulation of actin filament length GO:0030832 53 52 0,000 0,05502497 0,06106096 ! regulation of cell projection organization GO:0031344 55 52 0,000 0,05502497 0,06104199 ! chloride transport GO:0006821 53 52 0,000 0,05502497 0,06102304 ! muscle fiber development GO:0048747 55 52 0,000 0,05502497 0,06100409 ! regulation of muscle contraction GO:0006937 56 52 0,000 0,05502497 0,06098516 ! negative regulation of cytoskeleton organization GO:0051494 57 52 0,000 0,05502497 0,06096624 ! glucose catabolic process GO:0006007 52 52 0,000 0,05502497 0,06094733 ! generation of a signal involved in cell-cell signaling GO:0003001 54 52 0,000 0,05502497 0,06092843 ! small ribosomal subunit GO:0015935 52 52 0,000 0,05502497 0,06090954 ! cytokine receptor activity GO:0004896 53 52 0,000 0,05502497 0,06089067 ! activation of phospholipase C activity GO:0007202 55 53 0,000 0,05605478 0,06201103 GO:0010863|positive regulation of phospholipase C activity, ! nucleoside monophosphate metabolic process GO:0009123 58 53 0,000 0,05605478 0,06199183 ! N-acetyltransferase activity GO:0008080 54 53 0,000 0,05605478 0,06197264 ! synaptic vesicle GO:0008021 57 53 0,000 0,05605478 0,06195346 ! pyridoxal phosphate binding GO:0030170 56 53 0,000 0,05605478 0,06193429 GO:0070279|vitamin B6 binding, ! viral reproduction GO:0016032 57 53 0,000 0,05605478 0,06191513 ! cell projection assembly GO:0030031 56 53 0,000 0,05605478 0,06189598 ! embryonic skeletal system development GO:0048706 54 53 0,000 0,05605478 0,06187685 ! proton transport GO:0015992 53 53 0,000 0,05605478 0,06185773 ! mRNA binding GO:0003729 55 53 0,000 0,05605478 0,06183862 ! single fertilization GO:0007338 55 53 0,000 0,05605478 0,06181952 ! axon GO:0030424 58 54 0,000 0,05708353 0,06293464 ! heat shock protein binding GO:0031072 54 54 0,000 0,05708353 0,06291521 ! regulation of neurotransmitter levels GO:0001505 60 54 0,000 0,05708353 0,0628958 ! double-stranded DNA binding GO:0003690 55 54 0,000 0,05708353 0,0628764 ! positive regulation of phospholipase activity GO:0010518 56 54 0,000 0,05708353 0,06285701 ! tRNA processing GO:0008033 55 54 0,000 0,05708353 0,06283764 ! regulation of cellular response to stress GO:0080135 57 54 0,000 0,05708353 0,06281827 ! growth factor receptor binding GO:0070851 56 54 0,000 0,05708353 0,06279892 ! regulation of tissue remodeling GO:0034103 58 54 0,000 0,05708353 0,06277958 ! regulation of cellular component size GO:0032535 56 55 0,000 0,05811123 0,06389015 ! hydrogen transport GO:0006818 55 55 0,000 0,05811123 0,06387049 ! glycerophospholipid biosynthetic process GO:0046474 59 55 0,000 0,05811123 0,06385084 ! nucleotide-excision repair GO:0006289 58 55 0,000 0,05811123 0,0638312 ! large ribosomal subunit GO:0015934 56 55 0,000 0,05811123 0,06381157 ! protein amino acid autophosphorylation GO:0046777 57 55 0,000 0,05811123 0,06379195 ! positive regulation of secretion GO:0051047 60 56 0,000 0,05913789 0,06489901 ! actin filament organization GO:0007015 59 56 0,000 0,05913789 0,06487907 ! regulation of phospholipase activity GO:0010517 58 56 0,000 0,05913789 0,06485915 ! coenzyme biosynthetic process GO:0009108 59 56 0,000 0,05913789 0,06483924 ! cellular amino acid catabolic process GO:0009063 59 56 0,000 0,05913789 0,06481933 ! cartilage development GO:0051216 59 56 0,000 0,05913789 0,06479944 ! regulation of protein complex assembly GO:0043254 57 56 0,000 0,05913789 0,06477957 ! receptor signaling protein serine/threonine kinase activity GO:0004702 58 56 0,000 0,05913789 0,0647597 ! mesoderm development GO:0007498 57 56 0,000 0,05913789 0,06473985 ! camera-type eye development GO:0043010 59 56 0,000 0,05913789 0,06472001 ! regulation of transcription factor activity GO:0051090 59 57 0,000 0,06016349 0,06582225 GO:0090046|regulation of transcription regulator activity, ! ear development GO:0043583 60 57 0,000 0,06016349 0,06580209 ! chromosome segregation GO:0007059 59 57 0,000 0,06016349 0,06578194 ! positive regulation of T cell activation GO:0050870 62 57 0,000 0,06016349 0,0657618 ! kidney development GO:0001822 60 57 0,000 0,06016349 0,06574168 ! positive regulation of lipase activity GO:0060193 59 57 0,000 0,06016349 0,06572157 ! integrin-mediated signaling pathway GO:0007229 61 57 0,000 0,06016349 0,06570147 ! adult behavior GO:0030534 60 57 0,000 0,06016349 0,06568139 ! myosin complex GO:0016459 59 57 0,000 0,06016349 0,06566131 ! regulation of angiogenesis GO:0045765 60 58 0,000 0,06118804 0,06675909 ! lysosomal membrane GO:0005765 59 58 0,000 0,06118804 0,0667387 ! extracellular matrix organization GO:0030198 59 58 0,000 0,06118804 0,06671832 ! positive regulation of cell motion GO:0051272 61 58 0,000 0,06118804 0,06669795 ! homeostasis of number of cells GO:0048872 62 58 0,000 0,06118804 0,0666776 ! regulation of vesicle-mediated transport GO:0060627 60 58 0,000 0,06118804 0,06665726 ! detection of external stimulus GO:0009581 59 58 0,000 0,06118804 0,06663693 ! secondary metabolic process GO:0019748 59 58 0,000 0,06118804 0,06661662 ! translation initiation factor activity GO:0003743 58 58 0,000 0,06118804 0,06659631 ! dendrite GO:0030425 61 59 0,000 0,06221155 0,06768965 ! molecular adaptor activity GO:0060090 65 59 0,000 0,06221155 0,06766904 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 60 59 0,000 0,06221155 0,06764843 GO:0051213|dioxygenase activity, ! embryonic limb morphogenesis GO:0030326 63 59 0,000 0,06221155 0,06762784 GO:0035113|embryonic appendage morphogenesis, ! ubiquitin thiolesterase activity GO:0004221 62 59 0,000 0,06221155 0,06760726 ! regulation of heart contraction GO:0008016 62 59 0,000 0,06221155 0,06758669 ! copper ion binding GO:0005507 61 59 0,000 0,06221155 0,06756613 ! activation of immune response GO:0002253 68 59 0,000 0,06221155 0,06754559 ! aminoglycan metabolic process GO:0006022 62 59 0,000 0,06221155 0,06752506 ! amine transmembrane transporter activity GO:0005275 59 59 0,000 0,06221155 0,06750454 ! chromatin remodeling complex GO:0016585 61 59 0,000 0,06221155 0,06748404 ! cell soma GO:0043025 63 59 0,000 0,06221155 0,06746354 ! regulation of homeostatic process GO:0032844 68 59 0,000 0,06221155 0,06744306 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 61 60 0,000 0,06323401 0,0685307 ! multicellular organism reproduction GO:0032504 62 60 0,000 0,06323401 0,06850991 GO:0048609|reproductive process in a multicellular organism, ! occluding junction GO:0070160 60 60 0,000 0,06323401 0,06848913 GO:0005923|tight junction, ! regulation of lipid metabolic process GO:0019216 63 60 0,000 0,06323401 0,06846836 ! myeloid cell differentiation GO:0030099 64 60 0,000 0,06323401 0,06844761 ! oxygen and reactive oxygen species metabolic process GO:0006800 60 60 0,000 0,06323401 0,06842686 ! regulation of cytokine biosynthetic process GO:0042035 63 60 0,000 0,06323401 0,06840614 ! lymphocyte mediated immunity GO:0002449 63 60 0,000 0,06323401 0,06838542 ! chloride channel activity GO:0005254 61 60 0,000 0,06323401 0,06836471 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 62 61 0,000 0,06425543 0,06944798 ! cell cycle checkpoint GO:0000075 64 61 0,000 0,06425543 0,06942697 ! fertilization GO:0009566 64 61 0,000 0,06425543 0,06940597 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 65 61 0,000 0,06425543 0,06938498 ! gonad development GO:0008406 61 61 0,000 0,06425543 0,069364 ! protein maturation by peptide bond cleavage GO:0051605 64 61 0,000 0,06425543 0,06934304 ! regulation of immune effector process GO:0002697 65 61 0,000 0,06425543 0,06932209 ! amine catabolic process GO:0009310 68 62 0,000 0,0652758 0,07040165 ! phosphoinositide metabolic process GO:0030384 66 62 0,000 0,0652758 0,0703804 ! glycerolipid biosynthetic process GO:0045017 66 62 0,000 0,0652758 0,07035915 ! coated membrane GO:0048475 67 62 0,000 0,0652758 0,07033792 GO:0030117|membrane coat, ! hexose catabolic process GO:0019320 63 62 0,000 0,0652758 0,0703167 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 63 62 0,000 0,0652758 0,0702955 ! extracellular ligand-gated ion channel activity GO:0005230 67 62 0,000 0,0652758 0,07027431 ! germ cell development GO:0007281 62 62 0,000 0,0652758 0,07025313 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 70 63 0,000 0,06629513 0,07132868 ! negative regulation of ligase activity GO:0051352 64 63 0,000 0,06629513 0,0713072 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein oligomerization GO:0051259 64 63 0,000 0,06629513 0,07128573 ! transition metal ion transport GO:0000041 65 63 0,000 0,06629513 0,07126427 ! appendage morphogenesis GO:0035107 67 63 0,000 0,06629513 0,07124282 GO:0035108|limb morphogenesis, ! activation of MAPK activity GO:0000187 69 63 0,000 0,06629513 0,07122139 ! cellular defense response GO:0006968 64 63 0,000 0,06629513 0,07119997 ! B cell activation GO:0042113 66 63 0,000 0,06629513 0,07117856 ! antigen processing and presentation GO:0019882 64 63 0,000 0,06629513 0,07115717 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 65 63 0,000 0,06629513 0,07113579 ! microtubule motor activity GO:0003777 67 63 0,000 0,06629513 0,07111442 ! organelle localization GO:0051640 66 63 0,000 0,06629513 0,07109306 ! transforming growth factor beta receptor signaling pathway GO:0007179 67 64 0,000 0,06731341 0,07216337 ! lung development GO:0030324 65 64 0,000 0,06731341 0,07214172 ! developmental maturation GO:0021700 67 64 0,000 0,06731341 0,07212007 ! amino acid transport GO:0006865 64 64 0,000 0,06731341 0,07209844 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 66 64 0,000 0,06731341 0,07207682 ! anion channel activity GO:0005253 65 64 0,000 0,06731341 0,07205521 ! cellular hormone metabolic process GO:0034754 65 65 0,000 0,06833066 0,0731222 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 65 0,000 0,06833066 0,07310029 ! regulation of MAPKKK cascade GO:0043408 72 65 0,000 0,06833066 0,0730784 ! rhythmic process GO:0048511 66 65 0,000 0,06833066 0,07305652 ! regulation of lipase activity GO:0060191 67 65 0,000 0,06833066 0,07303465 ! adaptive immune response GO:0002250 68 65 0,000 0,06833066 0,0730128 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! appendage development GO:0048736 69 65 0,000 0,06833066 0,07299096 GO:0060173|limb development, ! skeletal system morphogenesis GO:0048705 66 65 0,000 0,06833066 0,07296913 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 67 65 0,000 0,06833066 0,07294732 ! lipoprotein metabolic process GO:0042157 68 65 0,000 0,06833066 0,07292552 ! DNA-dependent DNA replication GO:0006261 66 65 0,000 0,06833066 0,07290373 ! endoplasmic reticulum lumen GO:0005788 66 66 0,000 0,06934686 0,07396584 ! urogenital system development GO:0001655 69 66 0,000 0,06934686 0,07394376 ! response to steroid hormone stimulus GO:0048545 69 66 0,000 0,06934686 0,07392169 ! diacylglycerol binding GO:0019992 71 66 0,000 0,06934686 0,07389963 ! amine binding GO:0043176 70 66 0,000 0,06934686 0,07387758 ! response to nutrient GO:0007584 67 66 0,000 0,06934686 0,07385555 ! acetyltransferase activity GO:0016407 68 66 0,000 0,06934686 0,07383353 ! respiratory tube development GO:0030323 68 67 0,000 0,07036203 0,07489204 ! intracellular protein transmembrane transport GO:0065002 70 67 0,000 0,07036203 0,07486973 ! tubulin binding GO:0015631 70 67 0,000 0,07036203 0,07484742 ! activation of protein kinase activity GO:0032147 70 67 0,000 0,07036203 0,07482514 ! humoral immune response GO:0006959 70 67 0,000 0,07036203 0,07480286 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 69 67 0,000 0,07036203 0,0747806 ! ubiquitin ligase complex GO:0000151 71 67 0,000 0,07036203 0,07475835 ! nucleosome assembly GO:0006334 69 67 0,000 0,07036203 0,07473611 ! transcription initiation from RNA polymerase II promoter GO:0006367 71 67 0,000 0,07036203 0,07471389 ! muscle cell differentiation GO:0042692 68 68 0,000 0,07137616 0,07576821 ! fatty acid biosynthetic process GO:0006633 70 68 0,000 0,07137616 0,07574569 ! lymphocyte differentiation GO:0030098 75 68 0,000 0,07137616 0,07572319 ! protein-DNA complex GO:0032993 69 68 0,000 0,07137616 0,0757007 ! learning or memory GO:0007611 72 68 0,000 0,07137616 0,07567822 ! chloride ion binding GO:0031404 70 68 0,000 0,07137616 0,07565576 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 71 68 0,000 0,07137616 0,07563331 ! chromatin assembly GO:0031497 70 68 0,000 0,07137616 0,07561087 ! leukocyte mediated immunity GO:0002443 71 68 0,000 0,07137616 0,07558845 ! extrinsic to membrane GO:0019898 68 68 0,000 0,07137616 0,07556604 ! calcium channel activity GO:0005262 73 68 0,000 0,07137616 0,07554364 ! ribonucleoprotein complex assembly GO:0022618 69 68 0,000 0,07137616 0,07552126 ! respiratory system development GO:0060541 69 68 0,000 0,07137616 0,07549889 ! N-acyltransferase activity GO:0016410 69 68 0,000 0,07137616 0,07547653 ! eye development GO:0001654 74 69 0,000 0,07238925 0,07652516 ! positive regulation of ligase activity GO:0051351 71 69 0,000 0,07238925 0,07650251 ! sarcomere GO:0030017 75 69 0,000 0,07238925 0,07647988 ! cAMP-mediated signaling GO:0019933 72 69 0,000 0,07238925 0,07645726 ! axon guidance GO:0007411 74 69 0,000 0,07238925 0,07643465 ! regulation of DNA binding GO:0051101 72 70 0,000 0,0734013 0,07748036 ! carboxylic acid transmembrane transporter activity GO:0046943 71 70 0,000 0,0734013 0,07745746 ! early endosome GO:0005769 79 70 0,000 0,0734013 0,07743458 ! response to hypoxia GO:0001666 76 70 0,000 0,0734013 0,07741171 ! female pregnancy GO:0007565 71 70 0,000 0,0734013 0,07738885 ! rRNA processing GO:0006364 70 70 0,000 0,0734013 0,07736601 ! cytosolic ribosome GO:0022626 70 70 0,000 0,0734013 0,07734318 ! cell-matrix adhesion GO:0007160 76 71 0,000 0,07441232 0,07838537 ! FAD binding GO:0050660 72 71 0,000 0,07441232 0,07836225 ! response to oxygen levels GO:0070482 77 71 0,000 0,07441232 0,07833915 ! mitochondrial outer membrane GO:0005741 75 71 0,000 0,07441232 0,07831606 ! defense response to bacterium GO:0042742 71 71 0,000 0,07441232 0,07829298 ! steroid biosynthetic process GO:0006694 72 71 0,000 0,07441232 0,07826992 ! monosaccharide catabolic process GO:0046365 72 71 0,000 0,07441232 0,07824688 ! regulation of synaptic transmission GO:0050804 73 71 0,000 0,07441232 0,07822384 ! reproductive structure development GO:0048608 71 71 0,000 0,07441232 0,07820082 ! neurotransmitter transport GO:0006836 73 71 0,000 0,07441232 0,07817781 ! organic acid transmembrane transporter activity GO:0005342 72 71 0,000 0,07441232 0,07815482 ! phospholipase activity GO:0004620 75 71 0,000 0,07441232 0,07813184 ! cell projection part GO:0044463 75 71 0,000 0,07441232 0,07810887 ! amine biosynthetic process GO:0009309 75 72 0,000 0,0754223 0,07914577 ! meiosis GO:0007126 73 72 0,000 0,0754223 0,07912252 GO:0051327|M phase of meiotic cell cycle, ! elevation of cytosolic calcium ion concentration GO:0007204 77 72 0,000 0,0754223 0,07909928 ! acute inflammatory response GO:0002526 76 72 0,000 0,0754223 0,07907606 ! cholesterol metabolic process GO:0008203 74 72 0,000 0,0754223 0,07905285 ! lipid transporter activity GO:0005319 77 72 0,000 0,0754223 0,07902965 ! regulation of ubiquitin-protein ligase activity GO:0051438 74 72 0,000 0,0754223 0,07900647 ! negative regulation of transport GO:0051051 74 73 0,000 0,07643125 0,08003989 ! vacuolar membrane GO:0005774 74 73 0,000 0,07643125 0,08001642 ! rRNA metabolic process GO:0016072 73 73 0,000 0,07643125 0,07999297 ! meiotic cell cycle GO:0051321 75 73 0,000 0,07643125 0,07996953 ! negative regulation of organelle organization GO:0010639 78 73 0,000 0,07643125 0,07994611 ! regulation of protein transport GO:0051223 77 73 0,000 0,07643125 0,0799227 GO:0070201|regulation of establishment of protein localization, ! cytosolic calcium ion homeostasis GO:0051480 78 73 0,000 0,07643125 0,0798993 ! nucleosome organization GO:0034728 76 74 0,000 0,07743917 0,08092926 ! neuropeptide signaling pathway GO:0007218 79 74 0,000 0,07743917 0,08090558 ! myofibril GO:0030016 80 74 0,000 0,07743917 0,08088192 ! regulation of blood pressure GO:0008217 76 74 0,000 0,07743917 0,08085827 ! apical junction complex GO:0043296 74 74 0,000 0,07743917 0,08083464 ! cellular carbohydrate catabolic process GO:0044275 75 74 0,000 0,07743917 0,08081101 ! development of primary sexual characteristics GO:0045137 74 74 0,000 0,07743917 0,08078741 ! membrane raft GO:0045121 78 74 0,000 0,07743917 0,08076381 ! cellular response to hormone stimulus GO:0032870 81 74 0,000 0,07743917 0,08074023 ! serine-type endopeptidase inhibitor activity GO:0004867 75 74 0,000 0,07743917 0,08071666 ! response to drug GO:0042493 77 75 0,000 0,07844606 0,08174231 ! membrane lipid biosynthetic process GO:0046467 77 75 0,000 0,07844606 0,08171846 ! phosphoinositide-mediated signaling GO:0048015 79 75 0,000 0,07844606 0,08169463 ! tube morphogenesis GO:0035239 79 75 0,000 0,07844606 0,08167081 ! cellular lipid catabolic process GO:0044242 77 75 0,000 0,07844606 0,08164701 ! cysteine-type endopeptidase activity GO:0004197 75 75 0,000 0,07844606 0,08162322 ! structural constituent of cytoskeleton GO:0005200 81 75 0,000 0,07844606 0,08159944 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 80 76 0,000 0,07945192 0,08262167 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 76 76 0,000 0,07945192 0,08259761 ! regulation of ligase activity GO:0051340 78 76 0,000 0,07945192 0,08257357 ! vitamin metabolic process GO:0006766 77 76 0,000 0,07945192 0,08254955 ! inorganic anion transport GO:0015698 78 76 0,000 0,07945192 0,08252554 ! chromosome, centromeric region GO:0000775 78 76 0,000 0,07945192 0,08250154 ! apicolateral plasma membrane GO:0016327 76 76 0,000 0,07945192 0,08247756 ! T cell activation GO:0042110 82 76 0,000 0,07945192 0,08245359 ! digestion GO:0007586 80 76 0,000 0,07945192 0,08242963 ! cell-substrate adhesion GO:0031589 81 76 0,000 0,07945192 0,08240569 ! cilium GO:0005929 77 76 0,000 0,07945192 0,08238177 ! contractile fiber part GO:0044449 82 76 0,000 0,07945192 0,08235785 ! regulation of adenylate cyclase activity GO:0045761 80 77 0,000 0,08045675 0,08337523 ! nuclear speck GO:0016607 80 77 0,000 0,08045675 0,08335104 ! G-protein-coupled receptor binding GO:0001664 78 77 0,000 0,08045675 0,08332687 ! endonuclease activity GO:0004519 80 77 0,000 0,08045675 0,08330271 ! regulation of transmission of nerve impulse GO:0051969 79 77 0,000 0,08045675 0,08327856 ! hydrogen ion transmembrane transporter activity GO:0015078 78 77 0,000 0,08045675 0,08325443 ! extracellular matrix structural constituent GO:0005201 80 77 0,000 0,08045675 0,08323031 ! vacuolar part GO:0044437 78 77 0,000 0,08045675 0,08320621 ! thiolester hydrolase activity GO:0016790 81 78 0,000 0,08146055 0,08421992 ! potassium channel complex GO:0034705 81 78 0,000 0,08146055 0,08419555 GO:0008076|voltage-gated potassium channel complex, ! cofactor biosynthetic process GO:0051188 81 78 0,000 0,08146055 0,08417118 ! blood coagulation GO:0007596 81 78 0,000 0,08146055 0,08414684 GO:0050817|coagulation, ! phospholipid biosynthetic process GO:0008654 83 79 0,000 0,08246332 0,08515804 ! biogenic amine metabolic process GO:0006576 85 79 0,000 0,08246332 0,08513342 ! phosphoric diester hydrolase activity GO:0008081 82 79 0,000 0,08246332 0,08510882 ! positive regulation of MAP kinase activity GO:0043406 85 79 0,000 0,08246332 0,08508423 ! regulation of cyclase activity GO:0031279 82 79 0,000 0,08246332 0,08505965 ! regulation of neuron differentiation GO:0045664 82 79 0,000 0,08246332 0,08503509 ! regulation of T cell activation GO:0050863 84 79 0,000 0,08246332 0,08501054 ! regulation of cAMP biosynthetic process GO:0030817 82 79 0,000 0,08246332 0,08498601 ! exocytosis GO:0006887 81 79 0,000 0,08246332 0,08496149 ! nitrogen compound catabolic process GO:0044270 89 79 0,000 0,08246332 0,08493698 ! regulation of protein localization GO:0032880 83 79 0,000 0,08246332 0,08491249 ! regulation of DNA metabolic process GO:0051052 90 80 0,000 0,08346506 0,08591921 ! alcohol catabolic process GO:0046164 83 80 0,000 0,08346506 0,08589445 ! regulation of lyase activity GO:0051339 83 80 0,000 0,08346506 0,0858697 ! one-carbon metabolic process GO:0006730 87 80 0,000 0,08346506 0,08584497 ! monooxygenase activity GO:0004497 82 80 0,000 0,08346506 0,08582026 ! contractile fiber GO:0043292 86 80 0,000 0,08346506 0,08579555 ! protein ubiquitination GO:0016567 86 80 0,000 0,08346506 0,08577086 ! ossification GO:0001503 85 81 0,000 0,08446579 0,08677426 ! cellular carbohydrate biosynthetic process GO:0034637 83 81 0,000 0,08446579 0,0867493 ! sterol metabolic process GO:0016125 83 81 0,000 0,08446579 0,08672436 ! regulation of cAMP metabolic process GO:0030814 84 81 0,000 0,08446579 0,08669943 ! protein binding, bridging GO:0030674 86 81 0,000 0,08446579 0,08667452 ! regulation of neurological system process GO:0031644 83 81 0,000 0,08446579 0,08664962 ! positive regulation of immune response GO:0050778 91 82 0,000 0,08546548 0,08764998 ! regulation of defense response GO:0031347 82 82 0,000 0,08546548 0,08762482 ! bone development GO:0060348 86 82 0,000 0,08546548 0,08759967 ! carboxylesterase activity GO:0004091 86 82 0,000 0,08546548 0,08757453 ! transcription initiation GO:0006352 86 82 0,000 0,08546548 0,08754941 ! organelle outer membrane GO:0031968 87 83 0,000 0,08646415 0,08854703 ! SH3 domain binding GO:0017124 97 83 0,000 0,08646415 0,08852164 ! hemostasis GO:0007599 86 83 0,000 0,08646415 0,08849627 ! oxidative phosphorylation GO:0006119 83 83 0,000 0,08646415 0,08847092 ! heparin binding GO:0008201 90 83 0,000 0,08646415 0,08844557 ! amine transport GO:0015837 83 83 0,000 0,08646415 0,08842024 ! extracellular matrix part GO:0044420 85 83 0,000 0,08646415 0,08839493 ! phosphoinositide binding GO:0035091 90 83 0,000 0,08646415 0,08836963 ! regulation of nucleotide biosynthetic process GO:0030808 87 84 0,000 0,0874618 0,08936369 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 85 84 0,000 0,0874618 0,08933813 GO:0010498|proteasomal protein catabolic process, ! Ras GTPase activator activity GO:0005099 89 84 0,000 0,0874618 0,08931258 ! regulation of membrane potential GO:0042391 92 84 0,000 0,0874618 0,08928705 ! perinuclear region of cytoplasm GO:0048471 91 85 0,000 0,08845843 0,09027867 ! transmembrane receptor protein kinase activity GO:0019199 88 85 0,000 0,08845843 0,09025288 ! outer membrane GO:0019867 89 85 0,000 0,08845843 0,0902271 ! DNA recombination GO:0006310 86 85 0,000 0,08845843 0,09020133 ! neurotransmitter receptor activity GO:0030594 86 85 0,000 0,08845843 0,09017558 ! leukocyte differentiation GO:0002521 95 86 0,000 0,08945404 0,09116449 ! Golgi vesicle transport GO:0048193 86 86 0,000 0,08945404 0,09113848 ! neurotransmitter binding GO:0042165 88 86 0,000 0,08945404 0,09111249 ! anion binding GO:0043168 89 86 0,000 0,08945404 0,09108651 ! sex differentiation GO:0007548 86 86 0,000 0,08945404 0,09106054 ! UDP-glycosyltransferase activity GO:0008194 91 86 0,000 0,08945404 0,09103459 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 93 87 0,000 0,09044863 0,09202053 ! regulation of cyclic nucleotide metabolic process GO:0030799 90 87 0,000 0,09044863 0,09199432 ! protein processing GO:0016485 92 87 0,000 0,09044863 0,09196813 ! ATP-dependent helicase activity GO:0008026 92 88 0,000 0,0914422 0,09295192 GO:0070035|purine NTP-dependent helicase activity, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 89 88 0,000 0,0914422 0,09292547 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 89 88 0,000 0,0914422 0,09289903 ! skeletal muscle tissue development GO:0007519 92 88 0,000 0,0914422 0,09287261 GO:0060538|skeletal muscle organ development, ! lipase activity GO:0016298 92 88 0,000 0,0914422 0,0928462 ! detection of stimulus GO:0051606 90 88 0,000 0,0914422 0,09281981 ! carboxylic acid catabolic process GO:0046395 93 89 0,000 0,09243475 0,09380065 GO:0016054|organic acid catabolic process, ! sulfur metabolic process GO:0006790 90 89 0,000 0,09243475 0,09377401 ! negative regulation of multicellular organismal process GO:0051241 93 89 0,000 0,09243475 0,09374737 ! regulation of binding GO:0051098 93 90 0,000 0,09342629 0,09472609 ! intermediate filament GO:0005882 92 90 0,000 0,09342629 0,0946992 ! nuclear membrane GO:0031965 92 90 0,000 0,09342629 0,09467233 ! external side of plasma membrane GO:0009897 99 90 0,000 0,09342629 0,09464547 ! growth factor binding GO:0019838 92 90 0,000 0,09342629 0,09461863 ! regulation of nucleotide metabolic process GO:0006140 93 90 0,000 0,09342629 0,0945918 ! homophilic cell adhesion GO:0007156 93 91 0,000 0,09441681 0,09556758 ! protein modification by small protein conjugation GO:0032446 98 91 0,000 0,09441681 0,0955405 ! forebrain development GO:0030900 95 91 0,000 0,09441681 0,09551343 ! carbohydrate biosynthetic process GO:0016051 93 91 0,000 0,09441681 0,09548638 ! apical plasma membrane GO:0016324 96 91 0,000 0,09441681 0,09545935 ! intermediate filament cytoskeleton GO:0045111 93 91 0,000 0,09441681 0,09543233 ! structure-specific DNA binding GO:0043566 93 92 0,000 0,09540631 0,09640519 ! angiogenesis GO:0001525 95 92 0,000 0,09540631 0,09637792 ! glycerophospholipid metabolic process GO:0006650 98 92 0,000 0,09540631 0,09635066 ! clathrin-coated vesicle GO:0030136 100 92 0,000 0,09540631 0,09632342 ! gland development GO:0048732 95 92 0,000 0,09540631 0,0962962 ! DNA packaging GO:0006323 94 92 0,000 0,09540631 0,09626899 ! anatomical structure homeostasis GO:0060249 96 93 0,000 0,09639481 0,09723894 ! receptor complex GO:0043235 97 93 0,000 0,09639481 0,09721148 ! voltage-gated potassium channel activity GO:0005249 99 93 0,000 0,09639481 0,09718404 ! hormone metabolic process GO:0042445 96 93 0,000 0,09639481 0,09715661 ! translational elongation GO:0006414 97 94 0,000 0,09738229 0,09812419 ! nucleotidyltransferase activity GO:0016779 96 94 0,000 0,09738229 0,09809651 ! metalloendopeptidase activity GO:0004222 105 94 0,000 0,09738229 0,09806885 ! carbohydrate catabolic process GO:0016052 95 94 0,000 0,09738229 0,0980412 ! protein maturation GO:0051604 99 94 0,000 0,09738229 0,09801357 ! solute:cation symporter activity GO:0015294 95 94 0,000 0,09738229 0,09798595 ! in utero embryonic development GO:0001701 97 95 0,000 0,09836875 0,09895065 ! carboxylic acid binding GO:0031406 99 95 0,000 0,09836875 0,09892279 ! regulation of response to external stimulus GO:0032101 97 95 0,000 0,09836875 0,09889494 ! peroxisome GO:0005777 97 96 0,000 0,09935421 0,09985755 GO:0042579|microbody, ! integral to organelle membrane GO:0031301 96 96 0,000 0,09935421 0,09982946 ! translation factor activity, nucleic acid binding GO:0008135 99 96 0,000 0,09935421 0,09980137 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 97 96 0,000 0,09935421 0,09977331 ! cell fate commitment GO:0045165 98 96 0,000 0,09935421 0,09974526 ! response to nutrient levels GO:0031667 98 96 0,000 0,09935421 0,09971722 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 101 97 0,000 0,10033866 0,10067697 ! peptidyl-amino acid modification GO:0018193 99 97 0,000 0,10033866 0,10064869 ! reproductive developmental process GO:0003006 97 97 0,000 0,10033866 0,10062043 ! unfolded protein binding GO:0051082 100 98 0,000 0,10132209 0,1015781 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 99 98 0,000 0,10132209 0,10154959 ! polysaccharide metabolic process GO:0005976 102 98 0,000 0,10132209 0,1015211 ! protein modification by small protein conjugation or removal GO:0070647 105 98 0,000 0,10132209 0,10149262 ! protein C-terminus binding GO:0008022 106 99 0,000 0,10230452 0,10244797 ! anterior/posterior pattern formation GO:0009952 102 99 0,000 0,10230452 0,10241925 ! tRNA metabolic process GO:0006399 101 100 0,000 0,10328595 0,10337279 ! cytokine binding GO:0019955 101 100 0,000 0,10328595 0,10334383 ! regulation of cell morphogenesis GO:0022604 104 100 0,000 0,10328595 0,10331488 ! chromatin assembly or disassembly GO:0006333 104 100 0,000 0,10328595 0,10328595