pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/103-0-real-Ivshina_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle organization GO:0007051 46 32 3,000 6,762E-08 1,627E-04 ! activation of caspase activity by cytochrome c GO:0008635 14 8 2,000 9,518E-08 1,145E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 3,031E-07 2,431E-04 ! mitotic spindle organization GO:0007052 21 12 2,000 3,726E-07 2,241E-04 ! nuclear export GO:0051168 97 55 3,000 6,285E-07 3,024E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 7,266E-07 2,914E-04 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 1,147E-06 3,942E-04 ! protein export from nucleus GO:0006611 36 19 2,000 1,632E-06 4,907E-04 ! regulation of caspase activity GO:0043281 122 72 3,000 1,868E-06 4,993E-04 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 2,085E-06 5,017E-04 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 2,236E-06 4,89E-04 ! apoptotic nuclear changes GO:0030262 32 22 2,000 2,587E-06 5,186E-04 ! regulation of peptidase activity GO:0052547 134 79 3,000 2,711E-06 5,018E-04 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 3,394E-06 5,832E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 5,664E-06 9,086E-04 ! interphase GO:0051325 213 98 3,000 6,41E-06 9,64E-04 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,185E-05 1,677E-03 ! RNA export from nucleus GO:0006405 56 37 2,000 1,289E-05 1,722E-03 ! nucleus organization GO:0006997 67 38 2,000 1,398E-05 1,77E-03 ! negative regulation of protein ubiquitination GO:0031397 9 5 1,000 1,465E-05 1,763E-03 ! regulation of centrosome cycle GO:0046605 7 5 1,000 1,465E-05 1,679E-03 ! base conversion or substitution editing GO:0016553 5 5 1,000 1,465E-05 1,602E-03 ! activation of Ras GTPase activity GO:0032856 10 5 1,000 1,465E-05 1,533E-03 GO:0032862|activation of Rho GTPase activity, ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 2,337E-05 2,343E-03 ! cellular component disassembly GO:0022411 86 48 2,000 2,842E-05 2,735E-03 ! activation of caspase activity GO:0006919 84 48 2,000 2,842E-05 2,63E-03 ! microtubule nucleation GO:0007020 20 7 1,000 3,072E-05 2,738E-03 ! response to UV GO:0009411 104 53 2,000 3,833E-05 3,293E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 4,093E-05 3,396E-03 ! regulation of focal adhesion formation GO:0051893 22 8 1,000 4,093E-05 3,283E-03 ! positive regulation of caspase activity GO:0043280 95 55 2,000 4,285E-05 3,326E-03 GO:0010952|positive regulation of peptidase activity, ! keratinocyte proliferation GO:0043616 14 9 1,000 5,258E-05 3,954E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 5,258E-05 3,834E-03 ! DNA catabolic process GO:0006308 86 59 2,000 5,292E-05 3,745E-03 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 6,442E-05 4,429E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 6,568E-05 4,389E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 6,568E-05 4,271E-03 ! regulation of phosphatase activity GO:0010921 28 10 1,000 6,568E-05 4,158E-03 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 6,568E-05 4,052E-03 ! regulation of stress fiber formation GO:0051492 30 10 1,000 6,568E-05 3,95E-03 ! positive regulation of Rho GTPase activity GO:0032321 24 10 1,000 6,568E-05 3,854E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 7,745E-05 4,437E-03 ! regulation of actin filament bundle formation GO:0032231 33 11 1,000 8,021E-05 4,488E-03 ! negative regulation of kinase activity GO:0033673 131 68 2,000 8,096E-05 4,427E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 8,096E-05 4,329E-03 ! negative regulation of transferase activity GO:0051348 140 72 2,000 9,602E-05 5,022E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 9,618E-05 4,923E-03 ! positive regulation of cell growth GO:0030307 22 12 1,000 9,618E-05 4,821E-03 ! positive regulation of Ras GTPase activity GO:0032320 35 13 1,000 1,136E-04 5,577E-03 ! regulation of S phase GO:0033261 23 14 1,000 1,324E-04 6,371E-03 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 1,324E-04 6,246E-03 ! negative regulation of caspase activity GO:0043154 22 14 1,000 1,324E-04 6,126E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 1,324E-04 6,011E-03 ! positive regulation of cell size GO:0045793 27 15 1,000 1,527E-04 6,802E-03 ! response to unfolded protein GO:0006986 131 85 2,000 1,573E-04 6,88E-03 ! cellular respiration GO:0045333 135 88 2,000 1,743E-04 7,489E-03 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 1,743E-04 7,358E-03 ! regulation of dephosphorylation GO:0035303 43 16 1,000 1,743E-04 7,232E-03 ! neuron recognition GO:0008038 35 16 1,000 1,743E-04 7,109E-03 ! regulation of cell cycle process GO:0010564 149 90 2,000 1,863E-04 7,47E-03 ! response to protein stimulus GO:0051789 149 91 2,000 1,925E-04 7,592E-03 ! gene silencing by RNA GO:0031047 36 17 1,000 1,974E-04 7,661E-03 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 1,974E-04 7,539E-03 ! skin development GO:0043588 36 19 1,000 2,478E-04 9,317E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 2,478E-04 9,174E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! protein import into nucleus, docking GO:0000059 41 20 1,000 2,752E-04 0,01003102 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 2,752E-04 9,881E-03 ! negative regulation of translation GO:0017148 29 20 1,000 2,752E-04 9,736E-03 ! regulation of Rho GTPase activity GO:0032319 43 21 1,000 3,039E-04 0,01059667 ! positive regulation of B cell activation GO:0050871 38 22 1,000 3,34E-04 0,01148093 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 3,656E-04 0,01238765 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 3,656E-04 0,0122156 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 3,985E-04 0,01313339 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 3,985E-04 0,01295591 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 4,328E-04 0,013884 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 4,328E-04 0,01370132 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 4,328E-04 0,01352338 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 4,685E-04 0,01445131 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 5,056E-04 0,01539794 ! fat cell differentiation GO:0045444 50 27 1,000 5,056E-04 0,01520546 ! negative regulation of protein modification process GO:0031400 60 28 1,000 5,441E-04 0,01616044 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 5,441E-04 0,01596337 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 5,839E-04 0,01692616 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 5,839E-04 0,01672466 ! regulation of B cell activation GO:0050864 50 30 1,000 6,251E-04 0,01769477 ! response to heat GO:0009408 50 30 1,000 6,251E-04 0,01748901 ! regulation of ARF GTPase activity GO:0032312 65 32 1,000 7,117E-04 0,01968181 ! gene silencing GO:0016458 65 32 1,000 7,117E-04 0,01945816 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 8,518E-04 0,02302619 ! regulation of microtubule-based process GO:0032886 78 35 1,000 8,518E-04 0,02277034 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 1,004E-03 0,02654615 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! RNA modification GO:0009451 57 39 1,000 1,057E-03 0,02765555 ! keratinocyte differentiation GO:0030216 62 41 1,000 1,168E-03 0,03022814 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 1,285E-03 0,03288282 ! epidermal cell differentiation GO:0009913 68 46 1,000 1,469E-03 0,03720653 ! response to insulin stimulus GO:0032868 95 46 1,000 1,469E-03 0,03681896 ! response to calcium ion GO:0051592 81 47 1,000 1,533E-03 0,03802952 ! positive regulation of cell cycle GO:0045787 89 48 1,000 1,599E-03 0,03924771 ! regulation of ARF protein signal transduction GO:0032012 102 48 1,000 1,599E-03 0,03885127 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 1,599E-03 0,03846276 ! response to temperature stimulus GO:0009266 76 49 1,000 1,665E-03 0,03967179 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 1,803E-03 0,04252408 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of growth GO:0045927 90 52 1,000 1,873E-03 0,04376186 ! regulation of translational initiation GO:0006446 82 53 1,000 1,945E-03 0,04500595 ! cell recognition GO:0008037 85 54 1,000 2,019E-03 0,0462561 ! regulation of protein catabolic process GO:0042176 116 55 1,000 2,093E-03 0,04751207 ! positive regulation of organelle organization GO:0010638 100 56 1,000 2,169E-03 0,04877362 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 2,485E-03 0,0553677 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 2,568E-03 0,05667563 ! regulation of mitosis GO:0007088 105 63 1,000 2,736E-03 0,05984267 GO:0051783|regulation of nuclear division, ! negative regulation of cell growth GO:0030308 132 67 1,000 3,088E-03 0,06693092 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 3,179E-03 0,06829072 ! negative regulation of cell size GO:0045792 134 69 1,000 3,271E-03 0,06965312 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 3,271E-03 0,06904213 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 3,556E-03 0,07439592 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 3,556E-03 0,07375458 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 3,556E-03 0,0731242 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 3,752E-03 0,07649956 ! regulation of catabolic process GO:0009894 161 76 1,000 3,953E-03 0,07991799 ! regulation of actin filament-based process GO:0032970 152 77 1,000 4,055E-03 0,08130269 ! positive regulation of ligase activity GO:0051351 124 77 1,000 4,055E-03 0,08063077 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 4,055E-03 0,07996986 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 4,263E-03 0,08339287 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 4,263E-03 0,08272034 ! response to metal ion GO:0010038 140 80 1,000 4,369E-03 0,0840978 ! protein import into nucleus GO:0006606 158 80 1,000 4,369E-03 0,08343036 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 4,476E-03 0,08480358 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 161 81 1,000 4,476E-03 0,08414105 ! negative regulation of growth GO:0045926 155 84 1,000 4,805E-03 0,08962034 ! regulation of ligase activity GO:0051340 142 84 1,000 4,805E-03 0,08893095 ! positive regulation of cell activation GO:0050867 145 85 1,000 4,917E-03 0,09030904 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 5,03E-03 0,09168814 ! mitochondrion organization GO:0007005 148 86 1,000 5,03E-03 0,09099875 ! protein localization in nucleus GO:0034504 176 87 1,000 5,145E-03 0,09237364 ! positive regulation of protein modification process GO:0031401 136 88 1,000 5,26E-03 0,09374946 ! regulation of cell adhesion GO:0030155 212 89 1,000 5,377E-03 0,09512614 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 5,856E-03 0,1028439 GO:0010498|proteasomal protein catabolic process, ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 6,103E-03 0,10639763 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 6,128E-03 0,10607243 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 6,128E-03 0,10531477 ! positive regulation of helicase activity GO:0051096 11 5 0,000 6,128E-03 0,10456786 ! neuron fate determination GO:0048664 7 5 0,000 6,128E-03 0,10383146 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,128E-03 0,10310537 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 6,128E-03 0,10238936 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 6,128E-03 0,10168323 ! polyol transport GO:0015791 12 5 0,000 6,128E-03 0,10098677 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 6,128E-03 0,10029978 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 6,128E-03 0,09962208 ! response to superoxide GO:0000303 10 5 0,000 6,128E-03 0,09895347 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,128E-03 0,09829378 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 6,128E-03 0,09764283 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 6,128E-03 0,09700045 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 6,128E-03 0,09636646 ! female meiosis GO:0007143 7 5 0,000 6,128E-03 0,0957407 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 6,128E-03 0,09512302 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 6,128E-03 0,09451325 ! cobalt ion transport GO:0006824 11 5 0,000 6,128E-03 0,09391126 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 6,128E-03 0,09331688 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 6,128E-03 0,09272999 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 6,128E-03 0,09215042 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 6,128E-03 0,09157806 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 6,128E-03 0,09101276 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 6,128E-03 0,0904544 ! embryonic camera-type eye development GO:0031076 10 5 0,000 6,128E-03 0,08990285 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 6,128E-03 0,08935799 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 6,128E-03 0,08881968 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 6,128E-03 0,08828783 ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,128E-03 0,08776231 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 6,128E-03 0,087243 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 6,128E-03 0,08672981 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 6,128E-03 0,08622262 ! negative chemotaxis GO:0050919 14 5 0,000 6,128E-03 0,08572132 ! positive regulation of histone modification GO:0031058 5 5 0,000 6,128E-03 0,08522582 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,128E-03 0,08473602 ! sensory perception of bitter taste GO:0050913 7 5 0,000 6,128E-03 0,08425182 ! behavioral response to pain GO:0048266 9 5 0,000 6,128E-03 0,08377311 ! clathrin coat assembly GO:0048268 14 5 0,000 6,128E-03 0,08329982 ! Notch receptor processing GO:0007220 8 5 0,000 6,128E-03 0,08283184 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,128E-03 0,08236909 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 6,128E-03 0,08191149 ! micturition GO:0060073 9 5 0,000 6,128E-03 0,08145894 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 6,128E-03 0,08101136 ! copulation GO:0007620 9 5 0,000 6,128E-03 0,08056868 ! glial cell fate commitment GO:0021781 13 5 0,000 6,128E-03 0,0801308 ! protein maturation by protein folding GO:0022417 13 5 0,000 6,128E-03 0,07969766 ! spermidine metabolic process GO:0008216 7 5 0,000 6,128E-03 0,07926918 ! regulation of potassium ion transport GO:0043266 10 5 0,000 6,128E-03 0,07884528 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 6,128E-03 0,07842589 ! apoptotic cell clearance GO:0043277 20 5 0,000 6,128E-03 0,07801094 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 6,128E-03 0,07760036 ! lipoprotein particle clearance GO:0034381 10 5 0,000 6,128E-03 0,07719407 ! grooming behavior GO:0007625 6 5 0,000 6,128E-03 0,07679202 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 6,128E-03 0,07639413 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 6,128E-03 0,07600035 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,128E-03 0,0756106 ! response to protozoan GO:0001562 10 5 0,000 6,128E-03 0,07522484 ! positive regulation of glycolysis GO:0045821 14 5 0,000 6,128E-03 0,07484298 ! lymph vessel development GO:0001945 10 5 0,000 6,128E-03 0,07446499 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 6,128E-03 0,07409079 ! endochondral ossification GO:0001958 16 5 0,000 6,128E-03 0,07372034 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 6,128E-03 0,07335357 ! parathyroid gland development GO:0060017 13 5 0,000 6,128E-03 0,07299043 ! anagen GO:0042640 6 5 0,000 6,128E-03 0,07263088 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 6,128E-03 0,07227484 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 6,128E-03 0,07192228 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 6,128E-03 0,07157314 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 6,128E-03 0,07122738 ! dorsal spinal cord development GO:0021516 7 5 0,000 6,128E-03 0,07088494 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 6,128E-03 0,07054578 ! sphingoid catabolic process GO:0046521 6 5 0,000 6,128E-03 0,07020985 ! skeletal myofibril assembly GO:0014866 10 5 0,000 6,128E-03 0,0698771 ! smooth muscle tissue development GO:0048745 28 5 0,000 6,128E-03 0,06954749 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,128E-03 0,06922098 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 6,128E-03 0,06889751 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 6,128E-03 0,06857706 ! cardiac muscle fiber development GO:0048739 10 5 0,000 6,128E-03 0,06825957 ! transepithelial chloride transport GO:0030321 9 5 0,000 6,128E-03 0,06794501 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,128E-03 0,06763334 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 6,128E-03 0,06732451 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 6,128E-03 0,06701849 ! neutrophil mediated immunity GO:0002446 7 5 0,000 6,128E-03 0,06671524 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 6,128E-03 0,06641472 ! histidine catabolic process GO:0006548 6 5 0,000 6,128E-03 0,0661169 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 6,128E-03 0,06582173 ! microvillus organization GO:0032528 7 5 0,000 6,128E-03 0,06552919 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 6,128E-03 0,06523924 ! L-serine biosynthetic process GO:0006564 6 5 0,000 6,128E-03 0,06495184 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 6,128E-03 0,06466696 ! tryptophan metabolic process GO:0006568 9 5 0,000 6,128E-03 0,06438458 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 6,128E-03 0,06410464 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 6,128E-03 0,06382713 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 6,128E-03 0,06355202 ! polyol catabolic process GO:0046174 7 5 0,000 6,128E-03 0,06327926 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 6,128E-03 0,06300884 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 6,128E-03 0,06274071 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 6,128E-03 0,06247486 ! muscle cell migration GO:0014812 8 5 0,000 6,128E-03 0,06221126 ! mitochondrial fission GO:0000266 8 5 0,000 6,128E-03 0,06194986 ! sister chromatid cohesion GO:0007062 12 5 0,000 6,128E-03 0,06169066 ! mRNA transcription GO:0009299 9 5 0,000 6,128E-03 0,06143362 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 6,128E-03 0,0611787 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 6,128E-03 0,0609259 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 6,128E-03 0,06067518 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 6,128E-03 0,06042651 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 6,128E-03 0,06017987 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 6,128E-03 0,05993523 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 6,128E-03 0,05969258 ! response to food GO:0032094 6 5 0,000 6,128E-03 0,05945189 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 6,128E-03 0,05921312 ! positive regulation of transporter activity GO:0032411 8 5 0,000 6,128E-03 0,05897627 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 6,128E-03 0,05874131 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,128E-03 0,05850821 ! paraxial mesoderm development GO:0048339 14 5 0,000 6,128E-03 0,05827695 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 6,128E-03 0,05804751 ! forebrain neuron development GO:0021884 13 5 0,000 6,128E-03 0,05781987 ! lipoprotein catabolic process GO:0042159 11 5 0,000 6,128E-03 0,05759401 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 6,128E-03 0,05736991 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 6,128E-03 0,05714755 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,128E-03 0,0569269 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 6,128E-03 0,05670795 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 6,128E-03 0,05649068 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,128E-03 0,05627507 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 6,128E-03 0,05606109 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 6,128E-03 0,05584874 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 6,128E-03 0,05563799 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 6,128E-03 0,05542883 ! basic amino acid transport GO:0015802 11 5 0,000 6,128E-03 0,05522123 ! cellular glucose homeostasis GO:0001678 5 5 0,000 6,128E-03 0,05501518 ! early endosome to late endosome transport GO:0045022 12 5 0,000 6,128E-03 0,05481066 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,128E-03 0,05460766 ! depyrimidination GO:0045008 10 5 0,000 6,128E-03 0,05440615 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,128E-03 0,05420613 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 6,128E-03 0,05400757 ! zinc ion homeostasis GO:0055069 8 5 0,000 6,128E-03 0,05381047 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 6,128E-03 0,05361479 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 6,128E-03 0,05342054 ! forebrain morphogenesis GO:0048853 13 5 0,000 6,128E-03 0,05322768 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 6,128E-03 0,05303621 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 6,128E-03 0,05284612 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 6,128E-03 0,05265738 ! peptidyl-arginine modification GO:0018195 9 5 0,000 6,128E-03 0,05246999 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,128E-03 0,05228393 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,128E-03 0,05209918 ! response to arsenic GO:0046685 10 5 0,000 6,128E-03 0,05191573 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 6,128E-03 0,05173357 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 6,128E-03 0,05155268 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 6,128E-03 0,05137306 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 6,128E-03 0,05119468 ! response to cadmium ion GO:0046686 7 5 0,000 6,128E-03 0,05101754 ! bile acid biosynthetic process GO:0006699 6 5 0,000 6,128E-03 0,05084161 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 6,128E-03 0,0506669 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 6,128E-03 0,05049338 ! decidualization GO:0046697 11 5 0,000 6,128E-03 0,05032105 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 6,128E-03 0,05014989 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 6,128E-03 0,04997989 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 6,128E-03 0,04981104 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 6,128E-03 0,04964333 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 6,128E-03 0,04947674 ! neural tube patterning GO:0021532 7 5 0,000 6,128E-03 0,04931126 ! embryonic cleavage GO:0040016 6 5 0,000 6,128E-03 0,04914689 ! peroxisome fission GO:0016559 5 5 0,000 6,128E-03 0,04898361 ! histone demethylation GO:0016577 10 5 0,000 6,128E-03 0,04882142 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 6,128E-03 0,04866029 ! mitotic recombination GO:0006312 9 5 0,000 6,128E-03 0,04850022 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 6,128E-03 0,04834121 ! metaphase plate congression GO:0051310 7 5 0,000 6,128E-03 0,04818323 ! regulation of sterol transport GO:0032371 7 5 0,000 6,128E-03 0,04802628 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 6,128E-03 0,04787035 ! enteric nervous system development GO:0048484 8 5 0,000 6,128E-03 0,04771543 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 6,128E-03 0,04756151 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 6,128E-03 0,04740858 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 6,128E-03 0,04725663 ! muscle cell proliferation GO:0033002 11 5 0,000 6,128E-03 0,04710565 ! skeletal muscle regeneration GO:0043403 8 5 0,000 6,128E-03 0,04695563 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 6,128E-03 0,04680656 ! plasminogen activation GO:0031639 5 5 0,000 6,128E-03 0,04665844 ! B cell homeostasis GO:0001782 13 5 0,000 6,128E-03 0,04651125 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 6,128E-03 0,04636499 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 6,128E-03 0,04621965 ! metaphase GO:0051323 8 5 0,000 6,128E-03 0,04607521 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 6,128E-03 0,04593168 ! cellular response to nutrient GO:0031670 8 5 0,000 6,128E-03 0,04578903 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 6,128E-03 0,04564727 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 6,128E-03 0,04550638 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 6,128E-03 0,04536636 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 6,128E-03 0,0452272 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 6,128E-03 0,04508889 ! response to redox state GO:0051775 5 5 0,000 6,128E-03 0,04495143 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 6,128E-03 0,0448148 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 6,128E-03 0,04467899 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,128E-03 0,04454401 ! regulation of telomerase activity GO:0051972 6 5 0,000 6,128E-03 0,04440984 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,128E-03 0,04427648 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 6,128E-03 0,04414392 ! porphyrin catabolic process GO:0006787 12 5 0,000 6,128E-03 0,04401214 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 6,128E-03 0,04388115 ! striatum development GO:0021756 9 5 0,000 6,128E-03 0,04375094 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 6,128E-03 0,0436215 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 6,128E-03 0,04349283 ! glial cell migration GO:0008347 11 5 0,000 6,128E-03 0,0433649 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,128E-03 0,04323774 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 6,128E-03 0,04311131 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 6,128E-03 0,04298562 ! somatic stem cell maintenance GO:0035019 15 5 0,000 6,128E-03 0,04286066 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 6,128E-03 0,04273643 ! negative regulation of lipase activity GO:0060192 8 5 0,000 6,128E-03 0,04261291 ! neuroprotection GO:0043526 6 5 0,000 6,128E-03 0,04249011 ! neural plate development GO:0001840 8 5 0,000 6,128E-03 0,04236801 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 6,128E-03 0,04224661 ! regulation of sensory perception GO:0051931 7 5 0,000 6,128E-03 0,04212591 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 6,128E-03 0,04200589 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 6,128E-03 0,04188656 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 6,128E-03 0,0417679 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 6,128E-03 0,04164991 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 6,128E-03 0,04153259 ! sequestering of calcium ion GO:0051208 7 5 0,000 6,128E-03 0,04141592 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 6,128E-03 0,04129991 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 6,128E-03 0,04118455 ! spindle assembly GO:0051225 6 5 0,000 6,128E-03 0,04106983 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 6,128E-03 0,04095574 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 6,128E-03 0,04084229 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 6,128E-03 0,04072947 ! drug metabolic process GO:0017144 6 5 0,000 6,128E-03 0,04061727 ! stem cell division GO:0017145 11 5 0,000 6,128E-03 0,04050568 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 6,128E-03 0,04039471 ! organ regeneration GO:0031100 7 5 0,000 6,128E-03 0,04028434 ! carnitine metabolic process GO:0009437 7 5 0,000 6,128E-03 0,04017457 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 6,128E-03 0,0400654 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 6,128E-03 0,03995682 ! mRNA transport GO:0051028 169 96 1,000 6,228E-03 0,04049658 ! response to virus GO:0009615 160 98 1,000 6,481E-03 0,04203205 ! cell cycle arrest GO:0007050 213 100 1,000 6,74E-03 0,04358935 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 7,349E-03 0,04740567 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 7,349E-03 0,04727891 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 7,349E-03 0,04715284 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 7,349E-03 0,04702743 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 7,349E-03 0,04690269 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 7,349E-03 0,04677861 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 7,349E-03 0,04665518 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 7,349E-03 0,0465324 ! sleep GO:0030431 13 6 0,000 7,349E-03 0,04641027 ! response to oxygen radical GO:0000305 11 6 0,000 7,349E-03 0,04628878 ! positive regulation of axon extension GO:0045773 11 6 0,000 7,349E-03 0,04616792 ! myoblast cell fate commitment GO:0048625 16 6 0,000 7,349E-03 0,04604769 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 7,349E-03 0,04592809 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 7,349E-03 0,0458091 ! regulation of interferon-beta production GO:0032648 8 6 0,000 7,349E-03 0,04569073 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 7,349E-03 0,04557297 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 7,349E-03 0,04545582 ! forebrain regionalization GO:0021871 8 6 0,000 7,349E-03 0,04533927 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 7,349E-03 0,04522331 ! male meiosis GO:0007140 7 6 0,000 7,349E-03 0,04510794 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 7,349E-03 0,04499317 ! response to zinc ion GO:0010043 9 6 0,000 7,349E-03 0,04487897 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 7,349E-03 0,04476535 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 7,349E-03 0,04465231 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 7,349E-03 0,04453983 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 7,349E-03 0,04442792 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 7,349E-03 0,04431658 ! malate metabolic process GO:0006108 11 6 0,000 7,349E-03 0,04420578 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 7,349E-03 0,04409555 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 7,349E-03 0,04398586 ! protein refolding GO:0042026 15 6 0,000 7,349E-03 0,04387671 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 7,349E-03 0,0437681 ! opsonization GO:0008228 8 6 0,000 7,349E-03 0,04366003 ! mating behavior GO:0007617 7 6 0,000 7,349E-03 0,0435525 ! neuron remodeling GO:0016322 15 6 0,000 7,349E-03 0,04344549 ! erythrocyte maturation GO:0043249 7 6 0,000 7,349E-03 0,043339 ! embryonic hemopoiesis GO:0035162 14 6 0,000 7,349E-03 0,04323304 ! equilibrioception GO:0050957 14 6 0,000 7,349E-03 0,04312759 ! protein amino acid dealkylation GO:0008214 12 6 0,000 7,349E-03 0,04302266 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 7,349E-03 0,04291824 ! photoreceptor cell development GO:0042461 10 6 0,000 7,349E-03 0,04281432 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 7,349E-03 0,0427109 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 7,349E-03 0,04260799 ! response to interferon-gamma GO:0034341 15 6 0,000 7,349E-03 0,04250556 ! toxin metabolic process GO:0009404 11 6 0,000 7,349E-03 0,04240363 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 7,349E-03 0,04230219 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 7,349E-03 0,04220123 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 7,349E-03 0,04210075 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 7,349E-03 0,04200075 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 7,349E-03 0,04190122 ! cGMP-mediated signaling GO:0019934 13 6 0,000 7,349E-03 0,04180216 ! activation of MAPKKK activity GO:0000185 12 6 0,000 7,349E-03 0,04170357 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 7,349E-03 0,04160544 ! thymic T cell selection GO:0045061 12 6 0,000 7,349E-03 0,04150778 ! protein lipoylation GO:0009249 10 6 0,000 7,349E-03 0,04141057 ! cysteine metabolic process GO:0006534 10 6 0,000 7,349E-03 0,04131382 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 7,349E-03 0,04121751 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 7,349E-03 0,04112166 ! glutamate catabolic process GO:0006538 10 6 0,000 7,349E-03 0,04102625 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 7,349E-03 0,04093128 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 7,349E-03 0,04083675 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 7,349E-03 0,04074266 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 7,349E-03 0,040649 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 7,349E-03 0,04055577 ! hyperosmotic response GO:0006972 9 6 0,000 7,349E-03 0,04046296 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 7,349E-03 0,04037058 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 7,349E-03 0,04027862 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 7,349E-03 0,04018708 ! urea metabolic process GO:0019627 7 6 0,000 7,349E-03 0,04009595 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 7,349E-03 0,04000524 ! neutrophil activation GO:0042119 8 6 0,000 7,349E-03 0,03991493 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 7,349E-03 0,03982503 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 7,349E-03 0,03973554 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 7,349E-03 0,03964644 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 7,349E-03 0,03955775 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 7,349E-03 0,03946945 ! neuron apoptosis GO:0051402 9 6 0,000 7,349E-03 0,03938155 ! nucleoside salvage GO:0043174 9 6 0,000 7,349E-03 0,03929403 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 7,349E-03 0,0392069 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 7,349E-03 0,03912016 ! T cell mediated immunity GO:0002456 16 6 0,000 7,349E-03 0,03903381 ! negative regulation of platelet activation GO:0010544 9 6 0,000 7,349E-03 0,03894783 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 7,349E-03 0,03886223 ! carnitine transport GO:0015879 10 6 0,000 7,349E-03 0,038777 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 7,349E-03 0,03869215 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,349E-03 0,03860767 ! positive regulation of exocytosis GO:0045921 8 6 0,000 7,349E-03 0,03852356 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 7,349E-03 0,03843981 ! 5S class rRNA transcription GO:0042791 11 6 0,000 7,349E-03 0,03835643 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 7,349E-03 0,03827341 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 7,349E-03 0,03819074 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 7,349E-03 0,03810844 ! sodium ion homeostasis GO:0055078 11 6 0,000 7,349E-03 0,03802648 ! establishment of spindle localization GO:0051293 12 6 0,000 7,349E-03 0,03794488 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 7,349E-03 0,03786363 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 7,349E-03 0,03778272 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 7,349E-03 0,03770216 ! neural nucleus development GO:0048857 14 6 0,000 7,349E-03 0,03762194 ! response to UV-C GO:0010225 11 6 0,000 7,349E-03 0,03754207 ! astrocyte development GO:0014002 15 6 0,000 7,349E-03 0,03746253 ! protein targeting to lysosome GO:0006622 10 6 0,000 7,349E-03 0,03738333 ! purine base biosynthetic process GO:0009113 17 6 0,000 7,349E-03 0,03730446 ! interaction with symbiont GO:0051702 13 6 0,000 7,349E-03 0,03722592 ! regulation of dendrite development GO:0050773 16 6 0,000 7,349E-03 0,03714772 ! skeletal muscle contraction GO:0003009 6 6 0,000 7,349E-03 0,03706984 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 7,349E-03 0,03699229 ! response to copper ion GO:0046688 10 6 0,000 7,349E-03 0,03691506 ! response to exogenous dsRNA GO:0043330 10 6 0,000 7,349E-03 0,03683815 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 7,349E-03 0,03676157 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,349E-03 0,0366853 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 7,349E-03 0,03660935 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 7,349E-03 0,03653371 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 7,349E-03 0,03645838 ! regulation of dopamine secretion GO:0014059 14 6 0,000 7,349E-03 0,03638336 ! nucleoside catabolic process GO:0009164 7 6 0,000 7,349E-03 0,03630865 ! hair follicle maturation GO:0048820 7 6 0,000 7,349E-03 0,03623425 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 7,349E-03 0,03616015 ! Schwann cell development GO:0014044 15 6 0,000 7,349E-03 0,03608635 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 7,349E-03 0,03601286 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 7,349E-03 0,03593966 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 7,349E-03 0,03586676 ! subpallium development GO:0021544 10 6 0,000 7,349E-03 0,03579416 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 7,349E-03 0,03572185 ! histone ubiquitination GO:0016574 8 6 0,000 7,349E-03 0,03564983 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 7,349E-03 0,0355781 ! maintenance of organ identity GO:0048496 9 6 0,000 7,349E-03 0,03550665 ! G2 phase GO:0051319 16 6 0,000 7,349E-03 0,0354355 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 7,349E-03 0,03536463 ! establishment of planar polarity GO:0001736 7 6 0,000 7,349E-03 0,03529404 ! regulation of mast cell activation GO:0033003 12 6 0,000 7,349E-03 0,03522373 ! membrane to membrane docking GO:0022614 14 6 0,000 7,349E-03 0,03515371 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 7,349E-03 0,03508396 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 7,349E-03 0,03501448 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 7,349E-03 0,03494528 ! receptor internalization GO:0031623 10 6 0,000 7,349E-03 0,03487636 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 7,349E-03 0,0348077 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 7,349E-03 0,03473932 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 7,349E-03 0,0346712 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 7,349E-03 0,03460335 ! protein deubiquitination GO:0016579 14 6 0,000 7,349E-03 0,03453577 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 7,349E-03 0,03446845 ! protein destabilization GO:0031648 9 6 0,000 7,349E-03 0,03440139 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 7,349E-03 0,03433459 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 7,349E-03 0,03426805 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 7,349E-03 0,03420177 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 7,349E-03 0,03413574 ! progesterone metabolic process GO:0042448 10 6 0,000 7,349E-03 0,03406997 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 7,349E-03 0,03400445 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 7,349E-03 0,03393918 ! negative regulation of axon extension GO:0030517 21 6 0,000 7,349E-03 0,03387416 ! removal of superoxide radicals GO:0019430 11 6 0,000 7,349E-03 0,0338094 ! triglyceride catabolic process GO:0019433 10 6 0,000 7,349E-03 0,03374487 ! determination of adult lifespan GO:0008340 15 6 0,000 7,349E-03 0,0336806 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 7,349E-03 0,03361657 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 7,349E-03 0,03355278 ! cerebellar cortex formation GO:0021697 8 6 0,000 7,349E-03 0,03348923 ! catecholamine transport GO:0051937 9 6 0,000 7,349E-03 0,03342592 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 7,349E-03 0,03336286 ! sensory cilium assembly GO:0035058 10 6 0,000 7,349E-03 0,03330003 ! organ or tissue specific immune response GO:0002251 7 6 0,000 7,349E-03 0,03323743 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 7,349E-03 0,03317507 ! maternal placenta development GO:0001893 12 6 0,000 7,349E-03 0,03311295 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 7,349E-03 0,03305105 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 7,349E-03 0,03298939 ! negative regulation of B cell activation GO:0050869 13 6 0,000 7,349E-03 0,03292796 ! protein amino acid prenylation GO:0018346 16 6 0,000 7,349E-03 0,03286675 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 7,349E-03 0,03280578 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 7,349E-03 0,03274503 ! positive regulation of coagulation GO:0050820 12 6 0,000 7,349E-03 0,0326845 ! tRNA transcription GO:0009304 14 7 0,000 8,569E-03 0,03803883 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 8,569E-03 0,03796878 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 8,569E-03 0,03789898 ! behavioral response to cocaine GO:0048148 14 7 0,000 8,569E-03 0,03782944 ! regulation of helicase activity GO:0051095 15 7 0,000 8,569E-03 0,03776016 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 8,569E-03 0,03769113 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 8,569E-03 0,03762235 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 8,569E-03 0,03755382 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 8,569E-03 0,03748554 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 8,569E-03 0,03741751 ! prostate gland development GO:0030850 13 7 0,000 8,569E-03 0,03734972 ! nucleotide-sugar transport GO:0015780 12 7 0,000 8,569E-03 0,03728218 ! synaptonemal complex assembly GO:0007130 10 7 0,000 8,569E-03 0,03721489 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 8,569E-03 0,03714783 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 8,569E-03 0,03708102 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 8,569E-03 0,03701445 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 8,569E-03 0,03694811 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 8,569E-03 0,03688202 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 8,569E-03 0,03681616 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 8,569E-03 0,03675053 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 8,569E-03 0,03668514 ! SMAD protein complex assembly GO:0007183 12 7 0,000 8,569E-03 0,03661998 ! glycolipid transport GO:0046836 10 7 0,000 8,569E-03 0,03655505 ! protein amino acid sulfation GO:0006477 10 7 0,000 8,569E-03 0,03649035 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 8,569E-03 0,03642588 ! neuron adhesion GO:0007158 12 7 0,000 8,569E-03 0,03636164 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 8,569E-03 0,03629762 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 8,569E-03 0,03623383 ! actin-myosin filament sliding GO:0033275 11 7 0,000 8,569E-03 0,03617026 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 8,569E-03 0,03610691 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 8,569E-03 0,03604379 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 8,569E-03 0,03598089 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 8,569E-03 0,0359182 ! mRNA stabilization GO:0048255 18 7 0,000 8,569E-03 0,03585573 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 8,569E-03 0,03579348 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 8,569E-03 0,03573145 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 8,569E-03 0,03566963 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 8,569E-03 0,03560803 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 8,569E-03 0,03554663 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 8,569E-03 0,03548545 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 8,569E-03 0,03542448 ! lipoprotein transport GO:0042953 14 7 0,000 8,569E-03 0,03536372 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 8,569E-03 0,03530316 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 8,569E-03 0,03524282 ! rhythmic behavior GO:0007622 15 7 0,000 8,569E-03 0,03518267 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 8,569E-03 0,03512274 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 8,569E-03 0,03506301 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 8,569E-03 0,03500348 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 8,569E-03 0,03494415 ! regulation of odontogenesis GO:0042481 13 7 0,000 8,569E-03 0,03488502 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 8,569E-03 0,03482609 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 8,569E-03 0,03476736 ! mechanosensory behavior GO:0007638 14 7 0,000 8,569E-03 0,03470883 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 8,569E-03 0,0346505 ! positive regulation of isotype switching GO:0045830 15 7 0,000 8,569E-03 0,03459236 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 8,569E-03 0,03453442 ! protein-cofactor linkage GO:0018065 13 7 0,000 8,569E-03 0,03447667 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 8,569E-03 0,03441911 ! spinal cord patterning GO:0021511 13 7 0,000 8,569E-03 0,03436175 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 8,569E-03 0,03430457 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 8,569E-03 0,03424759 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 8,569E-03 0,03419079 ! adrenal gland development GO:0030325 17 7 0,000 8,569E-03 0,03413418 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 8,569E-03 0,03407776 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 8,569E-03 0,03402153 ! ovulation GO:0030728 9 7 0,000 8,569E-03 0,03396548 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 8,569E-03 0,03390962 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 8,569E-03 0,03385394 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 8,569E-03 0,03379844 ! proline biosynthetic process GO:0006561 10 7 0,000 8,569E-03 0,03374312 ! thyroid hormone generation GO:0006590 13 7 0,000 8,569E-03 0,03368799 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 8,569E-03 0,03363303 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 8,569E-03 0,03357825 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 8,569E-03 0,03352365 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 8,569E-03 0,03346923 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 8,569E-03 0,03341499 ! galactose metabolic process GO:0006012 13 7 0,000 8,569E-03 0,03336092 ! vesicle fusion GO:0006906 17 7 0,000 8,569E-03 0,03330702 ! response to dietary excess GO:0002021 8 7 0,000 8,569E-03 0,0332533 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 8,569E-03 0,03319975 ! intracellular pH reduction GO:0051452 11 7 0,000 8,569E-03 0,03314638 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 8,569E-03 0,03309317 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 8,569E-03 0,03304014 ! organ growth GO:0035265 15 7 0,000 8,569E-03 0,03298728 ! purine salvage GO:0043101 10 7 0,000 8,569E-03 0,03293458 ! nucleoside transport GO:0015858 8 7 0,000 8,569E-03 0,03288205 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 8,569E-03 0,03282969 ! parturition GO:0007567 14 7 0,000 8,569E-03 0,0327775 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 8,569E-03 0,03272547 ! rRNA modification GO:0000154 14 7 0,000 8,569E-03 0,03267361 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 8,569E-03 0,03262191 ! spindle checkpoint GO:0031577 15 7 0,000 8,569E-03 0,03257037 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 8,569E-03 0,032519 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 8,569E-03 0,03246779 ! macrophage differentiation GO:0030225 11 7 0,000 8,569E-03 0,03241674 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 8,569E-03 0,03236585 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 8,569E-03 0,03231512 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 8,569E-03 0,03226455 ! hyaluronan metabolic process GO:0030212 8 7 0,000 8,569E-03 0,03221414 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 8,569E-03 0,03216388 ! anterograde axon cargo transport GO:0008089 18 7 0,000 8,569E-03 0,03211378 ! fibrinolysis GO:0042730 10 7 0,000 8,569E-03 0,03206384 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 8,569E-03 0,03201405 ! eating behavior GO:0042755 7 7 0,000 8,569E-03 0,03196441 ! B cell lineage commitment GO:0002326 21 7 0,000 8,569E-03 0,03191493 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 8,569E-03 0,03186561 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 8,569E-03 0,03181643 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 8,569E-03 0,03176741 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 8,569E-03 0,03171853 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 8,569E-03 0,03166981 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 8,569E-03 0,03162124 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 8,569E-03 0,03157281 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 8,569E-03 0,03152454 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 8,569E-03 0,03147641 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 8,569E-03 0,03142843 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 8,569E-03 0,03138059 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 8,569E-03 0,0313329 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 8,569E-03 0,03128535 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 8,569E-03 0,03123795 ! regulation of meiosis GO:0040020 12 7 0,000 8,569E-03 0,03119069 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 8,569E-03 0,03114358 ! T cell lineage commitment GO:0002360 16 7 0,000 8,569E-03 0,0310966 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 8,569E-03 0,03104977 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 8,569E-03 0,03100308 ! oxygen homeostasis GO:0032364 12 7 0,000 8,569E-03 0,03095653 ! transcription termination GO:0006353 13 7 0,000 8,569E-03 0,03091012 ! response to tumor cell GO:0002347 13 7 0,000 8,569E-03 0,03086384 ! regulation of respiratory burst GO:0060263 11 7 0,000 8,569E-03 0,03081771 ! coenzyme A metabolic process GO:0015936 12 7 0,000 8,569E-03 0,03077171 ! anaphase GO:0051322 17 7 0,000 8,569E-03 0,03072585 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 8,569E-03 0,03068013 ! axonal fasciculation GO:0007413 18 7 0,000 8,569E-03 0,03063454 ! negative regulation of nuclear division GO:0051784 14 7 0,000 8,569E-03 0,03058909 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 8,569E-03 0,03054377 ! peptidyl-threonine modification GO:0018210 25 7 0,000 8,569E-03 0,03049859 ! diuresis GO:0030146 12 7 0,000 8,569E-03 0,03045354 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 8,569E-03 0,03040862 ! thiamin metabolic process GO:0006772 7 7 0,000 8,569E-03 0,03036384 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 8,569E-03 0,03031919 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 8,569E-03 0,03027467 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 8,569E-03 0,03023027 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 8,569E-03 0,03018601 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 8,569E-03 0,03014188 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 8,569E-03 0,03009788 ! melanin biosynthetic process GO:0042438 8 7 0,000 8,569E-03 0,030054 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 8,569E-03 0,03001026 ! dopamine biosynthetic process GO:0042416 18 7 0,000 8,569E-03 0,02996664 ! glycolipid catabolic process GO:0019377 15 7 0,000 8,569E-03 0,02992315 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 8,569E-03 0,02987978 ! lymph node development GO:0048535 10 7 0,000 8,569E-03 0,02983654 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 8,569E-03 0,02979342 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 8,569E-03 0,02975043 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 8,569E-03 0,02970756 ! endosome to lysosome transport GO:0008333 11 7 0,000 8,569E-03 0,02966482 ! protein modification by small protein removal GO:0070646 16 7 0,000 8,569E-03 0,02962219 ! adult feeding behavior GO:0008343 9 7 0,000 8,569E-03 0,02957969 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 8,569E-03 0,02953732 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 8,569E-03 0,02949506 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 8,569E-03 0,02945292 ! muscle adaptation GO:0043500 14 7 0,000 8,569E-03 0,02941091 ! embryonic heart tube development GO:0035050 10 7 0,000 8,569E-03 0,02936901 ! retina homeostasis GO:0001895 12 7 0,000 8,569E-03 0,02932724 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 8,569E-03 0,02928558 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 8,569E-03 0,02924404 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 8,569E-03 0,02920262 ! protein prenylation GO:0018342 18 7 0,000 8,569E-03 0,02916131 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 8,569E-03 0,02912012 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 8,569E-03 0,02907905 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 8,569E-03 0,02903809 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 9,787E-03 0,03311993 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 9,787E-03 0,03307342 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 9,787E-03 0,03302703 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 9,787E-03 0,03298077 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 9,787E-03 0,03293465 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 9,787E-03 0,03288865 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 9,787E-03 0,03284278 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 9,787E-03 0,03279704 ! neutral lipid catabolic process GO:0046461 13 8 0,000 9,787E-03 0,03275142 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 9,787E-03 0,03270593 ! meiotic prophase I GO:0007128 13 8 0,000 9,787E-03 0,03266057 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 9,787E-03 0,03261533 ! oligopeptide transport GO:0006857 15 8 0,000 9,787E-03 0,03257022 ! UTP metabolic process GO:0046051 8 8 0,000 9,787E-03 0,03252524 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 9,787E-03 0,03248037 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 9,787E-03 0,03243564 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 9,787E-03 0,03239102 ! macrophage chemotaxis GO:0048246 12 8 0,000 9,787E-03 0,03234653 ! succinate metabolic process GO:0006105 14 8 0,000 9,787E-03 0,03230216 ! membrane hyperpolarization GO:0060081 10 8 0,000 9,787E-03 0,03225791 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 9,787E-03 0,03221378 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 9,787E-03 0,03216977 ! T-helper 1 type immune response GO:0042088 12 8 0,000 9,787E-03 0,03212588 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 9,787E-03 0,03208211 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 9,787E-03 0,03203846 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 9,787E-03 0,03199493 ! ganglioside metabolic process GO:0001573 19 8 0,000 9,787E-03 0,03195152 ! reflex GO:0060004 16 8 0,000 9,787E-03 0,03190823 ! negative regulation of endocytosis GO:0045806 11 8 0,000 9,787E-03 0,03186505 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 9,787E-03 0,03182199 ! endothelial cell differentiation GO:0045446 17 8 0,000 9,787E-03 0,03177904 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 9,787E-03 0,03173622 ! glycerolipid catabolic process GO:0046503 13 8 0,000 9,787E-03 0,0316935 ! hemoglobin metabolic process GO:0020027 13 8 0,000 9,787E-03 0,0316509 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 9,787E-03 0,03160842 ! pigment granule organization GO:0048753 16 8 0,000 9,787E-03 0,03156605 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 9,787E-03 0,03152379 ! astrocyte differentiation GO:0048708 18 8 0,000 9,787E-03 0,03148165 ! histidine metabolic process GO:0006547 16 8 0,000 9,787E-03 0,03143962 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 9,787E-03 0,0313977 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 9,787E-03 0,03135589 ! glycine catabolic process GO:0006546 13 8 0,000 9,787E-03 0,03131419 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 9,787E-03 0,03127261 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 9,787E-03 0,03123113 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 9,787E-03 0,03118976 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 9,787E-03 0,03114851 ! regulation of pigmentation during development GO:0048070 24 8 0,000 9,787E-03 0,03110736 ! melanin metabolic process GO:0006582 15 8 0,000 9,787E-03 0,03106632 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 9,787E-03 0,03102539 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 9,787E-03 0,03098457 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 9,787E-03 0,03094385 ! macrophage activation GO:0042116 12 8 0,000 9,787E-03 0,03090324 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 9,787E-03 0,03086274 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 9,787E-03 0,03082235 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 9,787E-03 0,03078205 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 9,787E-03 0,03074187 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 9,787E-03 0,03070179 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 9,787E-03 0,03066181 ! regulation of vascular permeability GO:0043114 12 8 0,000 9,787E-03 0,03062194 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 9,787E-03 0,03058217 ! osteoblast development GO:0002076 16 8 0,000 9,787E-03 0,03054251 ! positive regulation of vasodilation GO:0045909 13 8 0,000 9,787E-03 0,03050294 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 9,787E-03 0,03046348 ! negative regulation of translational initiation GO:0045947 10 8 0,000 9,787E-03 0,03042412 ! Schwann cell differentiation GO:0014037 19 8 0,000 9,787E-03 0,03038487 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 9,787E-03 0,03034571 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 9,787E-03 0,03030666 ! response to UV-B GO:0010224 16 8 0,000 9,787E-03 0,0302677 ! protein targeting to vacuole GO:0006623 12 8 0,000 9,787E-03 0,03022885 ! protein retention in ER lumen GO:0006621 14 8 0,000 9,787E-03 0,03019009 ! intermediate filament organization GO:0045109 12 8 0,000 9,787E-03 0,03015144 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 9,787E-03 0,03011288 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 9,787E-03 0,03007442 ! cellular extravasation GO:0045123 12 8 0,000 9,787E-03 0,03003606 ! cardiac muscle cell development GO:0055013 13 8 0,000 9,787E-03 0,0299978 ! regulation of circadian rhythm GO:0042752 16 8 0,000 9,787E-03 0,02995963 ! response to antibiotic GO:0046677 11 8 0,000 9,787E-03 0,02992157 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 9,787E-03 0,02988359 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 9,787E-03 0,02984572 ! DNA topological change GO:0006265 12 8 0,000 9,787E-03 0,02980794 ! response to tropane GO:0014073 15 8 0,000 9,787E-03 0,02977025 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 9,787E-03 0,02973267 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 9,787E-03 0,02969517 ! melanosome transport GO:0032402 13 8 0,000 9,787E-03 0,02965777 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 9,787E-03 0,02962047 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 9,787E-03 0,02958326 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 9,787E-03 0,02954614 ! mast cell activation GO:0045576 14 8 0,000 9,787E-03 0,02950911 ! multicellular organismal aging GO:0010259 18 8 0,000 9,787E-03 0,02947218 ! dendrite morphogenesis GO:0048813 13 8 0,000 9,787E-03 0,02943534 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 9,787E-03 0,02939859 ! nucleosome disassembly GO:0006337 14 8 0,000 9,787E-03 0,02936193 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 9,787E-03 0,02932537 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 9,787E-03 0,0292889 ! leukocyte activation during immune response GO:0002366 13 8 0,000 9,787E-03 0,02925251 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 9,787E-03 0,02921622 ! establishment of chromosome localization GO:0051303 12 8 0,000 9,787E-03 0,02918001 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 9,787E-03 0,0291439 ! intracellular lipid transport GO:0032365 13 8 0,000 9,787E-03 0,02910788 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 9,787E-03 0,02907194 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 9,787E-03 0,02903609 ! regulation of macrophage activation GO:0043030 15 8 0,000 9,787E-03 0,02900033 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 9,787E-03 0,02896466 ! positive regulation of epidermis development GO:0045684 13 8 0,000 9,787E-03 0,02892908 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 9,787E-03 0,02889358 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 9,787E-03 0,02885818 ! hormone catabolic process GO:0042447 17 8 0,000 9,787E-03 0,02882285 ! positive regulation of glucose import GO:0046326 8 8 0,000 9,787E-03 0,02878762 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 9,787E-03 0,02875247 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 9,787E-03 0,0287174 ! ATP catabolic process GO:0006200 11 8 0,000 9,787E-03 0,02868243 ! blastocyst growth GO:0001832 19 8 0,000 9,787E-03 0,02864753 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 9,787E-03 0,02861272 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 9,787E-03 0,028578 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 9,787E-03 0,02854336 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 9,787E-03 0,0285088 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 9,787E-03 0,02847433 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 9,787E-03 0,02843994 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 9,787E-03 0,02840564 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 9,787E-03 0,02837141 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 9,787E-03 0,02833727 ! amino sugar catabolic process GO:0046348 10 8 0,000 9,787E-03 0,02830321 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 9,787E-03 0,02826923 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 9,787E-03 0,02823534 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 9,787E-03 0,02820152 ! behavioral response to nicotine GO:0035095 12 8 0,000 9,787E-03 0,02816779 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 9,787E-03 0,02813414 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 9,787E-03 0,02810056 ! NAD biosynthetic process GO:0009435 13 8 0,000 9,787E-03 0,02806707 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01100415 0,03151904 ! axon extension GO:0048675 15 9 0,000 0,01100415 0,03148156 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01100415 0,03144417 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01100415 0,03140687 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01100415 0,03136966 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01100415 0,03133253 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01100415 0,0312955 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01100415 0,03125855 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01100415 0,03122169 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01100415 0,03118491 ! phosphate transport GO:0006817 19 9 0,000 0,01100415 0,03114823 ! reproductive behavior GO:0019098 19 9 0,000 0,01100415 0,03111162 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01100415 0,03107511 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01100415 0,03103868 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01100415 0,03100233 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01100415 0,03096607 ! GTP metabolic process GO:0046039 9 9 0,000 0,01100415 0,0309299 ! RNA methylation GO:0001510 15 9 0,000 0,01100415 0,03089381 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01100415 0,0308578 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01100415 0,03082188 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01100415 0,03078604 ! artery development GO:0060840 24 9 0,000 0,01100415 0,03075028 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01100415 0,03071461 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01100415 0,03067902 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01100415 0,03064351 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01100415 0,03060808 ! chemosensory behavior GO:0007635 20 9 0,000 0,01100415 0,03057274 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01100415 0,03053748 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01100415 0,03050229 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01100415 0,03046719 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01100415 0,03043217 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01100415 0,03039723 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01100415 0,03036238 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01100415 0,0303276 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01100415 0,0302929 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01100415 0,03025828 ! protein targeting to ER GO:0045047 22 9 0,000 0,01100415 0,03022373 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01100415 0,03018927 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01100415 0,03015489 ! T cell selection GO:0045058 23 9 0,000 0,01100415 0,03012058 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,01100415 0,03008635 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01100415 0,0300522 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01100415 0,03001813 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01100415 0,02998414 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01100415 0,02995022 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01100415 0,02991637 ! mannose metabolic process GO:0006013 13 9 0,000 0,01100415 0,02988261 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01100415 0,02984892 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01100415 0,02981531 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01100415 0,02978177 ! receptor clustering GO:0043113 18 9 0,000 0,01100415 0,0297483 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01100415 0,02971492 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01100415 0,0296816 ! ruffle organization GO:0031529 15 9 0,000 0,01100415 0,02964837 ! retinol metabolic process GO:0042572 18 9 0,000 0,01100415 0,0296152 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01100415 0,02958211 ! behavioral fear response GO:0001662 22 9 0,000 0,01100415 0,0295491 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01100415 0,02951616 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01100415 0,02948329 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01100415 0,02945049 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01100415 0,02941777 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01100415 0,02938512 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01100415 0,02935254 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01100415 0,02932003 ! segment specification GO:0007379 13 9 0,000 0,01100415 0,0292876 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01100415 0,02925524 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01100415 0,02922295 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01100415 0,02919073 ! response to amine stimulus GO:0014075 13 9 0,000 0,01100415 0,02915858 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01100415 0,0291265 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01100415 0,0290945 ! erythrocyte development GO:0048821 15 9 0,000 0,01100415 0,02906256 ! gas homeostasis GO:0033483 16 9 0,000 0,01100415 0,02903069 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01100415 0,0289989 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01100415 0,02896717 ! renal water homeostasis GO:0003091 14 9 0,000 0,01100415 0,02893551 ! postreplication repair GO:0006301 22 9 0,000 0,01100415 0,02890392 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01100415 0,0288724 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01100415 0,02884095 ! icosanoid secretion GO:0032309 15 9 0,000 0,01100415 0,02880957 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01100415 0,02877825 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01100415 0,028747 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01100415 0,02871583 ! regulation of cell division GO:0051302 15 9 0,000 0,01100415 0,02868471 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01100415 0,02865367 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01100415 0,02862269 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01100415 0,02859178 ! sterol catabolic process GO:0016127 11 9 0,000 0,01100415 0,02856094 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01100415 0,02853016 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01100415 0,02849945 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01100415 0,02846881 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01100415 0,02843823 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01100415 0,02840772 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01100415 0,02837727 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01100415 0,02834689 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01100415 0,02831657 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01100415 0,02828632 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01100415 0,02825613 ! purine base metabolic process GO:0006144 21 9 0,000 0,01100415 0,028226 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01100415 0,02819594 ! pigment granule transport GO:0051904 17 9 0,000 0,01100415 0,02816595 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01100415 0,02813602 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01100415 0,02810615 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01100415 0,02807634 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01100415 0,0280466 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01100415 0,02801692 ! mitochondrion localization GO:0051646 15 9 0,000 0,01100415 0,02798731 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01221954 0,03104563 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01221954 0,03101288 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01221954 0,0309802 ! synapsis GO:0007129 13 10 0,000 0,01221954 0,03094759 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01221954 0,03091505 ! N-glycan processing GO:0006491 20 10 0,000 0,01221954 0,03088257 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01221954 0,03085017 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01221954 0,03081783 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01221954 0,03078556 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01221954 0,03075336 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01221954 0,03072122 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,01221954 0,03068916 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01221954 0,03065715 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01221954 0,03062522 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01221954 0,03059335 ! androgen metabolic process GO:0008209 17 10 0,000 0,01221954 0,03056155 ! phospholipid efflux GO:0033700 16 10 0,000 0,01221954 0,03052981 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01221954 0,03049814 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01221954 0,03046654 ! lung alveolus development GO:0048286 26 10 0,000 0,01221954 0,030435 ! pathogenesis GO:0009405 13 10 0,000 0,01221954 0,03040353 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01221954 0,03037212 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01221954 0,03034077 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01221954 0,0303095 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01221954 0,03027828 ! endoderm development GO:0007492 16 10 0,000 0,01221954 0,03024713 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01221954 0,03021604 ! arginine catabolic process GO:0006527 13 10 0,000 0,01221954 0,03018502 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01221954 0,03015406 ! proline metabolic process GO:0006560 13 10 0,000 0,01221954 0,03012317 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01221954 0,03009233 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01221954 0,03006156 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01221954 0,03003086 ! V(D)J recombination GO:0033151 28 10 0,000 0,01221954 0,03000021 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01221954 0,02996963 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01221954 0,02993911 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 18 10 0,000 0,01221954 0,02990866 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01221954 0,02987826 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01221954 0,02984793 ! multicellular organism growth GO:0035264 18 10 0,000 0,01221954 0,02981766 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01221954 0,02978745 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01221954 0,0297573 ! epithelial cell development GO:0002064 20 10 0,000 0,01221954 0,02972721 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01221954 0,02969718 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01221954 0,02966722 ! macroautophagy GO:0016236 17 10 0,000 0,01221954 0,02963731 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01221954 0,02960746 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01221954 0,02957768 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01221954 0,02954795 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01221954 0,02951828 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01221954 0,02948868 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01221954 0,02945913 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01221954 0,02942964 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01221954 0,02940021 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01221954 0,02937084 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01221954 0,02934153 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01221954 0,02931227 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01221954 0,02928308 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01221954 0,02925394 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01221954 0,02922486 ! response to dsRNA GO:0043331 20 10 0,000 0,01221954 0,02919584 ! DNA ligation GO:0006266 19 10 0,000 0,01221954 0,02916688 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01221954 0,02913797 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01221954 0,02910912 ! melanosome localization GO:0032400 16 10 0,000 0,01221954 0,02908033 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01221954 0,02905159 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01221954 0,02902291 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01221954 0,02899429 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01221954 0,02896572 ! mRNA cleavage GO:0006379 17 10 0,000 0,01221954 0,02893722 ! protein sumoylation GO:0016925 15 10 0,000 0,01221954 0,02890876 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01221954 0,02888036 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01221954 0,02885202 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01221954 0,02882374 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01221954 0,0287955 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01221954 0,02876733 ! salivary gland development GO:0007431 27 10 0,000 0,01221954 0,02873921 ! prophase GO:0051324 15 10 0,000 0,01221954 0,02871114 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01221954 0,02868313 ! apical protein localization GO:0045176 15 10 0,000 0,01221954 0,02865518 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01221954 0,02862727 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01221954 0,02859943 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01221954 0,02857163 ! midbrain development GO:0030901 13 10 0,000 0,01221954 0,02854389 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01221954 0,02851621 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01221954 0,02848858 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01221954 0,028461 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01221954 0,02843347 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01221954 0,028406 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01221954 0,02837858 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01221954 0,02835122 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01221954 0,0283239 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01221954 0,02829664 ! oocyte development GO:0048599 17 10 0,000 0,01221954 0,02826943 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01221954 0,02824228 ! blastocyst formation GO:0001825 17 10 0,000 0,01221954 0,02821517 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01221954 0,02818812 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01221954 0,02816112 ! activation of innate immune response GO:0002218 12 10 0,000 0,01221954 0,02813417 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01221954 0,02810728 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01221954 0,02808043 ! response to nicotine GO:0035094 20 10 0,000 0,01221954 0,02805364 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01221954 0,02802689 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01221954 0,0280002 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01221954 0,02797356 ! localization within membrane GO:0051668 20 10 0,000 0,01221954 0,02794697 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01343347 0,03069414 ! respiratory burst GO:0045730 17 11 0,000 0,01343347 0,03066502 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01343347 0,03063596 ! neuron fate specification GO:0048665 17 11 0,000 0,01343347 0,03060694 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01343347 0,03057799 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01343347 0,03054909 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01343347 0,03052024 ! thyroid gland development GO:0030878 26 11 0,000 0,01343347 0,03049145 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01343347 0,03046271 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01343347 0,03043402 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01343347 0,03040539 ! response to pain GO:0048265 24 11 0,000 0,01343347 0,03037682 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01343347 0,03034829 ! T cell proliferation GO:0042098 26 11 0,000 0,01343347 0,03031982 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01343347 0,03029141 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01343347 0,03026305 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01343347 0,03023474 ! bone resorption GO:0045453 16 11 0,000 0,01343347 0,03020648 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01343347 0,03017828 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01343347 0,03015012 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01343347 0,03012203 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01343347 0,03009398 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01343347 0,03006598 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01343347 0,03003804 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01343347 0,03001015 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01343347 0,02998231 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01343347 0,02995453 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01343347 0,02992679 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01343347 0,02989911 ! lipid digestion GO:0044241 18 11 0,000 0,01343347 0,02987147 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01343347 0,02984389 ! UV protection GO:0009650 19 11 0,000 0,01343347 0,02981636 ! adult heart development GO:0007512 14 11 0,000 0,01343347 0,02978888 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01343347 0,02976145 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01343347 0,02973407 ! temperature homeostasis GO:0001659 17 11 0,000 0,01343347 0,02970674 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01343347 0,02967946 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01343347 0,02965223 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01343347 0,02962505 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01343347 0,02959792 ! regulation of organ growth GO:0046620 13 11 0,000 0,01343347 0,02957084 ! pigment granule localization GO:0051875 20 11 0,000 0,01343347 0,02954381 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01343347 0,02951683 ! vasoconstriction GO:0042310 18 11 0,000 0,01343347 0,0294899 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01343347 0,02946302 ! embryonic axis specification GO:0000578 18 11 0,000 0,01343347 0,02943619 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01343347 0,0294094 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01343347 0,02938267 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01343347 0,02935598 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01343347 0,02932934 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01343347 0,02930275 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01343347 0,02927621 ! zymogen activation GO:0031638 15 11 0,000 0,01343347 0,02924971 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01343347 0,02922327 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01343347 0,02919687 ! nucleosome positioning GO:0016584 15 11 0,000 0,01343347 0,02917052 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01343347 0,02914421 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01343347 0,02911796 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01343347 0,02909175 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01343347 0,02906559 ! acid secretion GO:0046717 18 11 0,000 0,01343347 0,02903947 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01343347 0,0290134 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01343347 0,02898738 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01343347 0,02896141 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01343347 0,02893548 ! oocyte differentiation GO:0009994 18 11 0,000 0,01343347 0,0289096 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01343347 0,02888376 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01343347 0,02885798 ! cholesterol efflux GO:0033344 19 11 0,000 0,01343347 0,02883223 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01343347 0,02880654 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01343347 0,02878088 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01343347 0,02875528 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01343347 0,02872972 ! embryonic gut development GO:0048566 15 11 0,000 0,01343347 0,0287042 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01343347 0,02867873 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01343347 0,02865331 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01343347 0,02862793 ! defense response to fungus GO:0050832 13 11 0,000 0,01343347 0,0286026 ! developmental induction GO:0031128 19 11 0,000 0,01343347 0,02857731 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01343347 0,02855206 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01343347 0,02852686 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01343347 0,0285017 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01343347 0,02847659 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01343347 0,02845153 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01343347 0,0284265 ! nucleus localization GO:0051647 19 11 0,000 0,01343347 0,02840152 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01343347 0,02837659 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01464595 0,03091067 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01464595 0,03088358 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01464595 0,03085654 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01464595 0,03082954 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01464595 0,03080259 ! virus-host interaction GO:0019048 29 12 0,000 0,01464595 0,03077569 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01464595 0,03074883 ! cartilage condensation GO:0001502 20 12 0,000 0,01464595 0,03072203 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01464595 0,03069526 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01464595 0,03066855 ! protein complex disassembly GO:0043241 27 12 0,000 0,01464595 0,03064188 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01464595 0,03061526 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01464595 0,03058868 ! hippocampus development GO:0021766 26 12 0,000 0,01464595 0,03056215 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,01464595 0,03053567 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01464595 0,03050923 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01464595 0,03048284 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01464595 0,03045649 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01464595 0,03043019 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01464595 0,03040394 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01464595 0,03037773 ! drug transport GO:0015893 16 12 0,000 0,01464595 0,03035156 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01464595 0,03032544 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01464595 0,03029937 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01464595 0,03027334 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01464595 0,03024735 ! focal adhesion formation GO:0048041 35 12 0,000 0,01464595 0,03022141 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01464595 0,03019551 ! forebrain cell migration GO:0021885 21 12 0,000 0,01464595 0,03016966 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01464595 0,03014385 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01464595 0,03011809 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01464595 0,03009237 ! entry into host cell GO:0030260 32 12 0,000 0,01464595 0,03006669 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01464595 0,03004106 ! monoamine transport GO:0015844 18 12 0,000 0,01464595 0,03001547 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01464595 0,02998993 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01464595 0,02996442 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01464595 0,02993897 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01464595 0,02991355 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01464595 0,02988818 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01464595 0,02986285 ! protein homotetramerization GO:0051289 21 12 0,000 0,01464595 0,02983756 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01464595 0,02981232 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01464595 0,02978712 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01464595 0,02976196 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01464595 0,02973685 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01464595 0,02971177 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01464595 0,02968674 ! cranial nerve development GO:0021545 20 12 0,000 0,01464595 0,02966175 ! fucose catabolic process GO:0019317 22 12 0,000 0,01464595 0,02963681 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01464595 0,0296119 ! histone acetylation GO:0016573 26 12 0,000 0,01464595 0,02958704 ! histone methylation GO:0016571 26 12 0,000 0,01464595 0,02956222 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01464595 0,02953744 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01464595 0,0295127 ! gland morphogenesis GO:0022612 29 12 0,000 0,01464595 0,029488 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01464595 0,02946335 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01464595 0,02943873 ! T cell homeostasis GO:0043029 25 12 0,000 0,01464595 0,02941416 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01464595 0,02938963 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01464595 0,02936514 ! spleen development GO:0048536 22 12 0,000 0,01464595 0,02934069 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01464595 0,02931628 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01464595 0,02929191 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01464595 0,02926758 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01464595 0,02924329 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01464595 0,02921904 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01464595 0,02919483 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01464595 0,02917066 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01464595 0,02914654 ! response to cold GO:0009409 17 12 0,000 0,01464595 0,02912245 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01464595 0,0290984 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01464595 0,02907439 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01585698 0,03145252 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01585698 0,03142661 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01585698 0,03140074 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01585698 0,03137492 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01585698 0,03134914 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01585698 0,0313234 ! lipid localization GO:0010876 28 13 0,000 0,01585698 0,03129771 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01585698 0,03127205 ! organelle fusion GO:0048284 32 13 0,000 0,01585698 0,03124644 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01585698 0,03122087 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01585698 0,03119534 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01585698 0,03116986 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01585698 0,03114441 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01585698 0,03111901 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01585698 0,03109365 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01585698 0,03106833 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01585698 0,03104305 ! methionine metabolic process GO:0006555 27 13 0,000 0,01585698 0,03101781 ! plasma membrane organization GO:0007009 24 13 0,000 0,01585698 0,03099261 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01585698 0,03096745 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01585698 0,03094234 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01585698 0,03091726 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01585698 0,03089223 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01585698 0,03086724 ! response to X-ray GO:0010165 25 13 0,000 0,01585698 0,03084228 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01585698 0,03081737 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01585698 0,0307925 ! exocrine system development GO:0035272 32 13 0,000 0,01585698 0,03076766 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01585698 0,03074287 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01585698 0,03071812 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01585698 0,03069341 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01585698 0,03066873 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01585698 0,0306441 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01585698 0,03061951 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01585698 0,03059495 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01585698 0,03057044 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01585698 0,03054596 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01585698 0,03052152 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01585698 0,03049713 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01585698 0,03047277 ! ribosome assembly GO:0042255 17 13 0,000 0,01585698 0,03044845 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01585698 0,03042417 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01585698 0,03039992 ! chromatin silencing GO:0006342 26 13 0,000 0,01585698 0,03037572 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01585698 0,03035155 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01585698 0,03032743 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01585698 0,03030334 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01585698 0,03027929 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01585698 0,03025528 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01585698 0,0302313 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01585698 0,03020737 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01585698 0,03018347 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01585698 0,03015961 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01585698 0,03013579 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01585698 0,030112 ! embryonic placenta development GO:0001892 23 13 0,000 0,01585698 0,03008825 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01585698 0,03006454 ! insulin secretion GO:0030073 23 13 0,000 0,01585698 0,03004087 ! actin filament polymerization GO:0030041 24 13 0,000 0,01585698 0,03001723 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01585698 0,02999364 ! acrosome reaction GO:0007340 18 13 0,000 0,01585698 0,02997007 ! rRNA transcription GO:0009303 25 14 0,000 0,01706657 0,0322309 ! lactation GO:0007595 26 14 0,000 0,01706657 0,03220562 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01706657 0,03218038 ! reproductive cellular process GO:0048610 20 14 0,000 0,01706657 0,03215518 ! tRNA modification GO:0006400 20 14 0,000 0,01706657 0,03213002 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01706657 0,0321049 ! water transport GO:0006833 21 14 0,000 0,01706657 0,03207981 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01706657 0,03205477 ! non-recombinational repair GO:0000726 25 14 0,000 0,01706657 0,03202977 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01706657 0,0320048 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01706657 0,03197988 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01706657 0,03195499 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01706657 0,03193014 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01706657 0,03190533 ! palate development GO:0060021 31 14 0,000 0,01706657 0,03188056 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01706657 0,03185583 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01706657 0,03183113 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01706657 0,03180648 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01706657 0,03178186 ! arginine metabolic process GO:0006525 17 14 0,000 0,01706657 0,03175728 ! regulation of heart rate GO:0002027 24 14 0,000 0,01706657 0,03173274 ! organic alcohol transport GO:0015850 29 14 0,000 0,01706657 0,03170823 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01706657 0,03168377 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01706657 0,03165934 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01706657 0,03163495 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01706657 0,03161059 ! L-amino acid transport GO:0015807 30 14 0,000 0,01706657 0,03158628 ! bone mineralization GO:0030282 17 14 0,000 0,01706657 0,031562 ! stem cell development GO:0048864 43 14 0,000 0,01706657 0,03153776 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01706657 0,03151355 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01706657 0,03148939 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01706657 0,03146526 ! cerebellum development GO:0021549 21 14 0,000 0,01706657 0,03144117 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01706657 0,03141711 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01706657 0,03139309 ! response to gamma radiation GO:0010332 28 14 0,000 0,01706657 0,03136911 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01706657 0,03134516 ! cofactor transport GO:0051181 26 14 0,000 0,01706657 0,03132125 ! NADP metabolic process GO:0006739 24 14 0,000 0,01706657 0,03129738 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01706657 0,03127354 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01706657 0,03124974 ! intestinal absorption GO:0050892 25 14 0,000 0,01706657 0,03122598 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01706657 0,03120225 ! oxygen transport GO:0015671 21 14 0,000 0,01706657 0,03117856 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01706657 0,0311549 ! male genitalia development GO:0030539 24 14 0,000 0,01706657 0,03113128 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01706657 0,0311077 ! regulation of axon extension GO:0030516 37 14 0,000 0,01706657 0,03108415 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01706657 0,03106064 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0182747 0,03323427 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0182747 0,03320917 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,0182747 0,0331841 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,0182747 0,03315908 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0182747 0,03313409 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0182747 0,03310914 ! copper ion transport GO:0006825 20 15 0,000 0,0182747 0,03308423 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0182747 0,03305935 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0182747 0,03303451 ! sulfate transport GO:0008272 23 15 0,000 0,0182747 0,03300971 ! response to cAMP GO:0051591 22 15 0,000 0,0182747 0,03298495 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0182747 0,03296022 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0182747 0,03293553 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0182747 0,03291088 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0182747 0,03288627 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0182747 0,03286169 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0182747 0,03283715 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0182747 0,03281264 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0182747 0,03278817 ! pituitary gland development GO:0021983 29 15 0,000 0,0182747 0,03276374 ! vesicle coating GO:0006901 33 15 0,000 0,0182747 0,03273934 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,0182747 0,03271498 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0182747 0,03269066 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,0182747 0,03266637 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0182747 0,03264212 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,0182747 0,03261791 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0182747 0,03259373 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0182747 0,03256958 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0182747 0,03254548 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0182747 0,0325214 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0182747 0,03249737 ! histone deacetylation GO:0016575 20 15 0,000 0,0182747 0,03247337 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0182747 0,0324494 ! tissue regeneration GO:0042246 26 15 0,000 0,0182747 0,03242547 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0182747 0,03240158 ! water homeostasis GO:0030104 27 15 0,000 0,0182747 0,03237772 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0182747 0,03235389 ! muscle maintenance GO:0046716 26 15 0,000 0,0182747 0,0323301 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0182747 0,03230635 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0182747 0,03228263 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0182747 0,03225894 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0182747 0,03223529 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0182747 0,03221168 ! cell killing GO:0001906 29 15 0,000 0,0182747 0,0321881 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,0182747 0,03216455 ! detection of bacterium GO:0016045 18 15 0,000 0,0182747 0,03214104 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,0182747 0,03211756 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0182747 0,03209412 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0182747 0,03207071 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0182747 0,03204733 ! peptide hormone processing GO:0016486 23 15 0,000 0,0182747 0,03202399 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,0194814 0,03411371 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,0194814 0,0340889 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,0194814 0,03406413 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,0194814 0,03403939 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,0194814 0,03401469 ! bone remodeling GO:0046849 27 16 0,000 0,0194814 0,03399002 ! filopodium assembly GO:0046847 32 16 0,000 0,0194814 0,03396539 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,0194814 0,0339408 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,0194814 0,03391624 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,0194814 0,03389171 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,0194814 0,03386722 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,0194814 0,03384277 ! startle response GO:0001964 28 16 0,000 0,0194814 0,03381835 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,0194814 0,03379397 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,0194814 0,03376962 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,0194814 0,03374531 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,0194814 0,03372104 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,0194814 0,03369679 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,0194814 0,03367259 ! protein polyubiquitination GO:0000209 34 16 0,000 0,0194814 0,03364841 ! glutamate metabolic process GO:0006536 22 16 0,000 0,0194814 0,03362427 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,0194814 0,03360017 ! response to osmotic stress GO:0006970 25 16 0,000 0,0194814 0,0335761 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,0194814 0,03355207 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,0194814 0,03352807 ! fructose metabolic process GO:0006000 25 16 0,000 0,0194814 0,0335041 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,0194814 0,03348017 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,0194814 0,03345627 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,0194814 0,03343241 ! negative regulation of immune response GO:0050777 35 16 0,000 0,0194814 0,03340858 ! axon cargo transport GO:0008088 43 16 0,000 0,0194814 0,03338479 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,0194814 0,03336102 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,0194814 0,0333373 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,0194814 0,0333136 ! DNA replication initiation GO:0006270 27 16 0,000 0,0194814 0,03328994 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,0194814 0,03326632 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,0194814 0,03324272 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,0194814 0,03321916 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,0194814 0,03319564 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,0194814 0,03317214 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,0194814 0,03314868 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,0194814 0,03312526 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,0194814 0,03310186 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,0194814 0,0330785 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,0194814 0,03305518 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,0194814 0,03303188 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,0194814 0,03300862 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,0194814 0,03298539 ! defense response to virus GO:0051607 37 16 0,000 0,0194814 0,03296219 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,02068664 0,03497686 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,02068664 0,03495229 ! metencephalon development GO:0022037 30 17 0,000 0,02068664 0,03492777 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,02068664 0,03490327 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,02068664 0,03487881 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,02068664 0,03485439 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,02068664 0,03483 ! signal complex assembly GO:0007172 41 17 0,000 0,02068664 0,03480564 ! endothelial cell migration GO:0043542 28 17 0,000 0,02068664 0,03478132 ! inositol metabolic process GO:0006020 28 17 0,000 0,02068664 0,03475703 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,02068664 0,03473278 ! glial cell development GO:0021782 27 17 0,000 0,02068664 0,03470855 ! limbic system development GO:0021761 36 17 0,000 0,02068664 0,03468437 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,02068664 0,03466021 ! adult walking behavior GO:0007628 33 17 0,000 0,02068664 0,03463609 ! heart looping GO:0001947 30 17 0,000 0,02068664 0,03461201 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,02068664 0,03458795 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,02068664 0,03456394 ! myoblast differentiation GO:0045445 45 17 0,000 0,02068664 0,03453995 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,02068664 0,034516 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,02068664 0,03449208 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,02068664 0,03446819 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,02068664 0,03444434 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02068664 0,03442052 ! glycine metabolic process GO:0006544 28 17 0,000 0,02068664 0,03439673 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,02068664 0,03437297 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02068664 0,03434925 ! NAD metabolic process GO:0019674 29 17 0,000 0,02068664 0,03432556 ! membrane budding GO:0006900 37 17 0,000 0,02068664 0,03430191 ! DNA integration GO:0015074 29 17 0,000 0,02068664 0,03427828 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,02068664 0,03425469 ! regulation of protein binding GO:0043393 33 17 0,000 0,02068664 0,03423113 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,02068664 0,03420761 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,02068664 0,03418411 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,02068664 0,03416065 ! genitalia development GO:0048806 30 17 0,000 0,02068664 0,03413722 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,02068664 0,03411382 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,02068664 0,03409046 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,02068664 0,03406712 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,02068664 0,03404382 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,02068664 0,03402055 ! steroid catabolic process GO:0006706 31 17 0,000 0,02068664 0,03399731 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,02068664 0,03397411 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,02068664 0,03395093 ! gas transport GO:0015669 25 17 0,000 0,02068664 0,03392779 ! organic cation transport GO:0015695 31 17 0,000 0,02068664 0,03390468 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,02068664 0,0338816 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,02068664 0,03385855 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,02068664 0,03383553 ! microspike assembly GO:0030035 36 17 0,000 0,02068664 0,03381255 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,02068664 0,03378959 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,02068664 0,03376667 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,02189045 0,03570741 ! neuron maturation GO:0042551 42 18 0,000 0,02189045 0,03568322 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,02189045 0,03565906 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,02189045 0,03563493 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,02189045 0,03561084 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,02189045 0,03558677 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,02189045 0,03556275 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,02189045 0,03553875 ! memory GO:0007613 31 18 0,000 0,02189045 0,03551479 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02189045 0,03549085 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,02189045 0,03546695 ! patterning of blood vessels GO:0001569 39 18 0,000 0,02189045 0,03544309 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,02189045 0,03541925 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,02189045 0,03539545 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,02189045 0,03537168 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,02189045 0,03534794 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02189045 0,03532423 ! response to retinoic acid GO:0032526 26 18 0,000 0,02189045 0,03530055 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,02189045 0,03527691 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,02189045 0,0352533 ! response to fungus GO:0009620 21 18 0,000 0,02189045 0,03522972 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,02189045 0,03520617 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,02189045 0,03518265 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,02189045 0,03515916 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,02189045 0,03513571 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,02189045 0,03511228 ! vitamin transport GO:0051180 27 18 0,000 0,02189045 0,03508889 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,02189045 0,03506553 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,02189045 0,0350422 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,02189045 0,0350189 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,02189045 0,03499563 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,02189045 0,03497239 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,02189045 0,03494919 ! nerve development GO:0021675 28 18 0,000 0,02189045 0,03492601 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,02189045 0,03490287 ! protein secretion GO:0009306 39 19 0,000 0,02309282 0,03679558 ! positive regulation of translation GO:0045727 30 19 0,000 0,02309282 0,03677123 ! negative regulation of defense response GO:0031348 25 19 0,000 0,02309282 0,03674691 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,02309282 0,03672262 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,02309282 0,03669836 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,02309282 0,03667414 ! lipid phosphorylation GO:0046834 35 19 0,000 0,02309282 0,03664995 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02309282 0,03662579 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,02309282 0,03660166 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,02309282 0,03657757 ! bile acid metabolic process GO:0008206 29 19 0,000 0,02309282 0,0365535 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,02309282 0,03652947 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,02309282 0,03650547 ! cerebral cortex development GO:0021987 36 19 0,000 0,02309282 0,0364815 ! pigmentation during development GO:0048066 41 19 0,000 0,02309282 0,03645756 ! response to vitamin A GO:0033189 27 19 0,000 0,02309282 0,03643365 ! heme metabolic process GO:0042168 36 19 0,000 0,02309282 0,03640978 ! actin filament bundle formation GO:0051017 42 19 0,000 0,02309282 0,03638593 ! neuromuscular junction development GO:0007528 34 19 0,000 0,02309282 0,03636212 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,02309282 0,03633834 ! plasma membrane fusion GO:0045026 28 19 0,000 0,02309282 0,03631459 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,02309282 0,03629087 ! peptide cross-linking GO:0018149 37 19 0,000 0,02309282 0,03626718 ! heart process GO:0003015 30 19 0,000 0,02309282 0,03624352 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,02309282 0,0362199 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,02309282 0,0361963 ! visual learning GO:0008542 36 19 0,000 0,02309282 0,03617274 ! cellular pigmentation GO:0033059 36 19 0,000 0,02309282 0,0361492 ! G1 phase GO:0051318 40 19 0,000 0,02309282 0,0361257 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,02309282 0,03610222 ! cell-cell junction organization GO:0045216 35 19 0,000 0,02309282 0,03607878 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,02309282 0,03605537 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,02309282 0,03603199 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,02309282 0,03600863 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,02309282 0,03598531 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,02309282 0,03596202 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,02309282 0,03593876 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,02309282 0,03591553 ! cilium assembly GO:0042384 37 19 0,000 0,02309282 0,03589233 ! peptide hormone secretion GO:0030072 31 19 0,000 0,02309282 0,03586916 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,02429375 0,03771017 ! positive regulation of ossification GO:0045778 47 20 0,000 0,02429375 0,03768585 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,02429375 0,03766157 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,02429375 0,03763732 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,02429375 0,0376131 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,02429375 0,03758891 ! cAMP metabolic process GO:0046058 36 20 0,000 0,02429375 0,03756475 ! response to vitamin GO:0033273 31 20 0,000 0,02429375 0,03754063 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,02429375 0,03751653 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,02429375 0,03749247 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,02429375 0,03746843 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,02429375 0,03744443 ! response to alkaloid GO:0043279 38 20 0,000 0,02429375 0,03742046 ! retinoid metabolic process GO:0001523 32 20 0,000 0,02429375 0,03739652 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,02429375 0,03737261 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,02429375 0,03734873 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,02429375 0,03732488 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,02429375 0,03730106 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,02429375 0,03727727 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,02429375 0,03725351 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,02429375 0,03722978 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,02429375 0,03720608 ! body fluid secretion GO:0007589 31 20 0,000 0,02429375 0,03718242 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,02429375 0,03715878 ! peptide secretion GO:0002790 35 20 0,000 0,02429375 0,03713517 ! stem cell differentiation GO:0048863 53 20 0,000 0,02429375 0,03711159 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,02429375 0,03708804 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,02429375 0,03706453 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,02429375 0,03704104 ! sensory perception of pain GO:0019233 30 20 0,000 0,02429375 0,03701758 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,02429375 0,03699415 ! diencephalon development GO:0021536 34 20 0,000 0,02429375 0,03697075 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,02429375 0,03694738 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,02429375 0,03692404 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,02429375 0,03690073 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,02429375 0,03687745 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,02429375 0,0368542 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,02429375 0,03683098 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,02429375 0,03680778 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,02429375 0,03678462 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,02429375 0,03676148 ! regulation of glucose import GO:0046324 29 20 0,000 0,02429375 0,03673838 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,02429375 0,0367153 ! actin filament-based movement GO:0030048 43 20 0,000 0,02429375 0,03669225 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,02429375 0,03666923 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,02429375 0,03664624 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,02429375 0,03662328 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,02429375 0,03660035 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,02429375 0,03657745 ! regulation of cell killing GO:0031341 42 21 0,000 0,02549324 0,03835944 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,02549324 0,03833546 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,02549324 0,03831152 ! hormone secretion GO:0046879 38 21 0,000 0,02549324 0,0382876 ! glycerol metabolic process GO:0006071 34 21 0,000 0,02549324 0,03826372 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,02549324 0,03823986 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,02549324 0,03821604 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,02549324 0,03819224 ! axis specification GO:0009798 38 21 0,000 0,02549324 0,03816847 ! ovarian follicle development GO:0001541 35 21 0,000 0,02549324 0,03814474 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,02549324 0,03812103 ! smooth muscle contraction GO:0006939 46 21 0,000 0,02549324 0,03809735 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,02549324 0,0380737 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,02549324 0,03805009 ! cell aging GO:0007569 44 21 0,000 0,02549324 0,0380265 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,02549324 0,03800294 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,02549324 0,0379794 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,02549324 0,0379559 ! cytolysis GO:0019835 24 21 0,000 0,02549324 0,03793243 ! vasodilation GO:0042311 39 21 0,000 0,02549324 0,03790898 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,02549324 0,03788557 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,02549324 0,03786218 ! oogenesis GO:0048477 36 21 0,000 0,02549324 0,03783883 ! DNA modification GO:0006304 34 21 0,000 0,02549324 0,0378155 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,02549324 0,0377922 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,02549324 0,03776893 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,02549324 0,03774568 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,02549324 0,03772247 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,02549324 0,03769929 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,02549324 0,03767613 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,02549324 0,037653 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,02549324 0,0376299 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,02549324 0,03760683 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,02549324 0,03758379 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,02549324 0,03756077 ! collagen catabolic process GO:0030574 28 21 0,000 0,02549324 0,03753778 ! sperm-egg recognition GO:0035036 21 21 0,000 0,02549324 0,03751482 ! gut development GO:0048565 39 21 0,000 0,02549324 0,03749189 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,0266913 0,03922985 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,0266913 0,0392059 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,0266913 0,03918198 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,0266913 0,03915809 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,0266913 0,03913423 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,0266913 0,03911039 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,0266913 0,03908659 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,0266913 0,03906281 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,0266913 0,03903907 ! regeneration GO:0031099 41 22 0,000 0,0266913 0,03901535 ! keratinization GO:0031424 28 22 0,000 0,0266913 0,03899166 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,0266913 0,038968 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,0266913 0,03894437 ! sensory perception of taste GO:0050909 28 22 0,000 0,0266913 0,03892077 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,0266913 0,03889719 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,0266913 0,03887365 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,0266913 0,03885013 ! vacuolar transport GO:0007034 36 22 0,000 0,0266913 0,03882664 ! lysosome organization GO:0007040 41 22 0,000 0,0266913 0,03880318 ! central nervous system neuron development GO:0021954 46 22 0,000 0,0266913 0,03877975 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,0266913 0,03875635 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,0266913 0,03873297 ! fucose metabolic process GO:0006004 39 22 0,000 0,0266913 0,03870962 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,0266913 0,0386863 ! ureteric bud development GO:0001657 43 22 0,000 0,0266913 0,03866301 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,0266913 0,03863975 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,0266913 0,03861652 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,0266913 0,03859331 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,0266913 0,03857013 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,0266913 0,03854698 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,0266913 0,03852385 ! sarcomere organization GO:0045214 30 22 0,000 0,0266913 0,03850076 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,0266913 0,03847769 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,0266913 0,03845465 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,0266913 0,03843164 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,0266913 0,03840865 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,0266913 0,03838569 ! protein stabilization GO:0050821 39 22 0,000 0,0266913 0,03836276 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,02788792 0,04005871 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,02788792 0,04003481 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,02788792 0,04001094 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,02788792 0,03998709 ! gluconeogenesis GO:0006094 33 23 0,000 0,02788792 0,03996328 ! viral genome replication GO:0019079 41 23 0,000 0,02788792 0,03993949 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,02788792 0,03991573 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,02788792 0,039892 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,02788792 0,0398683 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,02788792 0,03984462 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,02788792 0,03982098 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,02788792 0,03979736 ! visual behavior GO:0007632 42 23 0,000 0,02788792 0,03977377 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,02788792 0,0397502 ! response to ethanol GO:0045471 46 23 0,000 0,02788792 0,03972667 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,02788792 0,03970316 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,02788792 0,03967968 ! peroxisome organization GO:0007031 37 23 0,000 0,02788792 0,03965623 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,02788792 0,03963281 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,02788792 0,03960941 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,02788792 0,03958604 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,02788792 0,0395627 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,02788792 0,03953939 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,02788792 0,0395161 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,02788792 0,03949285 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,02788792 0,03946961 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,02788792 0,03944641 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,02788792 0,03942323 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,02788792 0,03940008 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,02788792 0,03937696 ! fatty acid transport GO:0015908 44 23 0,000 0,02788792 0,03935387 ! platelet activation GO:0030168 37 23 0,000 0,02788792 0,0393308 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,02788792 0,03930776 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,02788792 0,03928474 ! hormone transport GO:0009914 40 23 0,000 0,02788792 0,03926176 ! cell-cell recognition GO:0009988 25 23 0,000 0,02788792 0,0392388 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,02788792 0,03921586 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,02788792 0,03919296 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,02788792 0,03917008 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,02788792 0,03914723 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,02788792 0,0391244 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,02908312 0,04077738 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,02908312 0,04075363 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,02908312 0,04072991 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,02908312 0,04070621 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,02908312 0,04068255 ! vesicle docking GO:0048278 47 24 0,000 0,02908312 0,04065891 ! spinal cord development GO:0021510 47 24 0,000 0,02908312 0,0406353 ! vacuole organization GO:0007033 43 24 0,000 0,02908312 0,04061171 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,02908312 0,04058815 ! digestive system process GO:0022600 39 24 0,000 0,02908312 0,04056463 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,02908312 0,04054112 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,02908312 0,04051765 ! regulation of behavior GO:0050795 43 24 0,000 0,02908312 0,0404942 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,02908312 0,04047078 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,02908312 0,04044739 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,02908312 0,04042402 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,02908312 0,04040068 ! membrane depolarization GO:0051899 39 24 0,000 0,02908312 0,04037737 ! pallium development GO:0021543 49 24 0,000 0,02908312 0,04035408 ! pentose metabolic process GO:0019321 35 24 0,000 0,02908312 0,04033082 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,02908312 0,04030759 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,02908312 0,04028439 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,02908312 0,04026121 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,02908312 0,04023806 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,02908312 0,04021493 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,02908312 0,04019183 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,02908312 0,04016876 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,02908312 0,04014571 ! regulation of amine transport GO:0051952 40 24 0,000 0,02908312 0,04012269 ! protein tetramerization GO:0051262 52 24 0,000 0,02908312 0,0400997 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,03027688 0,04172175 ! myelination GO:0042552 45 25 0,000 0,03027688 0,04169787 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,03027688 0,04167401 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,03027688 0,04165019 ! phototransduction GO:0007602 33 25 0,000 0,03027688 0,04162639 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,03027688 0,04160261 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,03027688 0,04157887 ! sperm motility GO:0030317 31 25 0,000 0,03027688 0,04155515 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,03027688 0,04153146 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,03027688 0,04150779 ! receptor metabolic process GO:0043112 46 25 0,000 0,03027688 0,04148415 ! chromosome condensation GO:0030261 45 25 0,000 0,03027688 0,04146054 ! response to starvation GO:0042594 42 25 0,000 0,03027688 0,04143696 ! osteoblast differentiation GO:0001649 60 25 0,000 0,03027688 0,0414134 ! neural crest cell development GO:0014032 54 25 0,000 0,03027688 0,04138987 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,03027688 0,04136637 ! negative regulation of cell development GO:0010721 73 25 0,000 0,03027688 0,04134289 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,03027688 0,04131944 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,03027688 0,04129602 ! interaction with host GO:0051701 62 25 0,000 0,03027688 0,04127262 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,03027688 0,04124925 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,03027688 0,0412259 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,03027688 0,04120259 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,03027688 0,0411793 ! immunoglobulin production GO:0002377 55 25 0,000 0,03027688 0,04115603 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,03027688 0,04113279 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,03027688 0,04110958 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,03027688 0,04108639 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,03027688 0,04106323 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,03027688 0,0410401 ! telomere organization GO:0032200 43 25 0,000 0,03027688 0,04101699 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,03027688 0,04099391 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,03027688 0,04097085 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,03146922 0,04256039 ! embryonic pattern specification GO:0009880 44 26 0,000 0,03146922 0,04253648 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,03146922 0,0425126 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,03146922 0,04248874 ! initiation of viral infection GO:0019059 57 26 0,000 0,03146922 0,04246491 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,03146922 0,04244111 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,03146922 0,04241733 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,03146922 0,04239358 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,03146922 0,04236986 ! molting cycle process GO:0022404 50 26 0,000 0,03146922 0,04234616 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,03146922 0,04232249 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,03146922 0,04229885 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,03146922 0,04227523 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,03146922 0,04225164 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,03146922 0,04222807 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,03146922 0,04220453 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,03146922 0,04218102 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,03146922 0,04215753 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,03146922 0,04213407 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,03146922 0,04211064 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,03146922 0,04208723 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,03146922 0,04206385 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,03146922 0,0420405 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,03146922 0,04201717 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,03146922 0,04199386 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,03146922 0,04197058 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,03146922 0,04194733 ! blastocyst development GO:0001824 49 26 0,000 0,03146922 0,0419241 ! leukocyte proliferation GO:0070661 52 26 0,000 0,03146922 0,0419009 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,03146922 0,04187773 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,03146922 0,04185458 ! neuron fate commitment GO:0048663 48 27 0,000 0,03266012 0,04341451 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,03266012 0,04339054 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,03266012 0,04336659 ! iron ion transport GO:0006826 59 27 0,000 0,03266012 0,04334267 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,03266012 0,04331878 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,03266012 0,04329491 ! protein amino acid acylation GO:0043543 55 27 0,000 0,03266012 0,04327107 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,03266012 0,04324725 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,03266012 0,04322347 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,03266012 0,0431997 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,03266012 0,04317597 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,03266012 0,04315226 ! autophagy GO:0006914 41 27 0,000 0,03266012 0,04312857 ! male gonad development GO:0008584 44 27 0,000 0,03266012 0,04310491 ! response to toxin GO:0009636 47 27 0,000 0,03266012 0,04308128 ! primary neural tube formation GO:0014020 51 27 0,000 0,03266012 0,04305768 ! base-excision repair GO:0006284 41 27 0,000 0,03266012 0,0430341 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,03266012 0,04301054 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,03266012 0,04298701 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,03266012 0,04296351 ! glutathione metabolic process GO:0006749 39 27 0,000 0,03266012 0,04294003 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,03266012 0,04291658 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,03266012 0,04289315 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,03266012 0,04286975 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,03266012 0,04284638 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,03384961 0,04438265 ! circadian rhythm GO:0007623 50 28 0,000 0,03384961 0,04435847 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,03384961 0,04433433 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,03384961 0,04431021 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,03384961 0,04428611 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,03384961 0,04426204 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,03384961 0,044238 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,03384961 0,04421398 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,03384961 0,04418999 ! synaptogenesis GO:0007416 42 28 0,000 0,03384961 0,04416603 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,03384961 0,04414209 ! lipid oxidation GO:0034440 43 28 0,000 0,03384961 0,04411818 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,03384961 0,04409429 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,03384961 0,04407043 ! translational initiation GO:0006413 65 29 0,000 0,03503767 0,04559255 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,03503767 0,04556791 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,03503767 0,04554329 ! regulation of pH GO:0006885 43 29 0,000 0,03503767 0,0455187 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,03503767 0,04549414 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,03503767 0,0454696 ! catechol metabolic process GO:0009712 54 29 0,000 0,03503767 0,04544509 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,03503767 0,0454206 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,03503767 0,04539614 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,03503767 0,04537171 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,03503767 0,0453473 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,03503767 0,04532292 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,03503767 0,04529857 ! cell fate determination GO:0001709 60 29 0,000 0,03503767 0,04527424 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,03503767 0,04524994 ! detection of light stimulus GO:0009583 38 29 0,000 0,03503767 0,04522566 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,03503767 0,04520141 ! tissue homeostasis GO:0001894 48 29 0,000 0,03503767 0,04517719 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,03503767 0,04515299 ! phenol metabolic process GO:0018958 55 30 0,000 0,03622431 0,04665722 ! zinc ion transport GO:0006829 45 30 0,000 0,03622431 0,04663226 ! membrane docking GO:0022406 61 30 0,000 0,03622431 0,04660732 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,03622431 0,04658241 ! cell junction assembly GO:0034329 78 30 0,000 0,03622431 0,04655753 ! regulation of innate immune response GO:0045088 51 30 0,000 0,03622431 0,04653267 ! acute-phase response GO:0006953 49 30 0,000 0,03622431 0,04650784 ! myofibril assembly GO:0030239 47 30 0,000 0,03622431 0,04648303 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,03622431 0,04645826 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,03622431 0,0464335 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,03622431 0,04640878 ! phospholipid transport GO:0015914 51 30 0,000 0,03622431 0,04638408 ! ensheathment of neurons GO:0007272 57 30 0,000 0,03622431 0,04635941 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,03622431 0,04633476 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,03622431 0,04631014 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,03622431 0,04628555 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,03622431 0,04626098 ! eye morphogenesis GO:0048592 60 30 0,000 0,03622431 0,04623644 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,03740953 0,04772393 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,03740953 0,04769864 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,03740953 0,04767337 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,03740953 0,04764813 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,03740953 0,04762292 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,03740953 0,04759774 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,03740953 0,04757258 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,03740953 0,04754745 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,03740953 0,04752235 ! ovulation cycle process GO:0022602 49 31 0,000 0,03740953 0,04749727 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,03740953 0,04747222 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,03740953 0,04744719 ! peptide transport GO:0015833 55 31 0,000 0,03740953 0,04742219 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,03740953 0,04739722 ! iron ion homeostasis GO:0055072 54 31 0,000 0,03740953 0,04737228 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,03740953 0,04734736 ! mesoderm formation GO:0001707 69 31 0,000 0,03740953 0,04732246 ! natural killer cell activation GO:0030101 45 31 0,000 0,03740953 0,0472976 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,03740953 0,04727275 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,03740953 0,04724794 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,03740953 0,04722315 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,03740953 0,04719839 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,03740953 0,04717365 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,03859333 0,04864094 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,03859333 0,04861547 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,03859333 0,04859003 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,03859333 0,04856462 ! cholesterol transport GO:0030301 56 32 0,000 0,03859333 0,04853923 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,03859333 0,04851387 ! spliceosome assembly GO:0000245 67 32 0,000 0,03859333 0,04848854 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,03859333 0,04846323 ! metanephros development GO:0001656 74 32 0,000 0,03859333 0,04843795 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,03859333 0,0484127 ! response to ionizing radiation GO:0010212 65 32 0,000 0,03859333 0,04838747 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,03859333 0,04836227 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,03859333 0,04833709 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,03859333 0,04831194 ! muscle cell development GO:0055001 49 32 0,000 0,03859333 0,04828682 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,03859333 0,04826172 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,03859333 0,04823665 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,03859333 0,04821161 ! ovulation cycle GO:0042698 51 32 0,000 0,03859333 0,04818659 ! peripheral nervous system development GO:0007422 64 32 0,000 0,03859333 0,04816159 ! BMP signaling pathway GO:0030509 64 32 0,000 0,03859333 0,04813663 ! hindbrain development GO:0030902 61 32 0,000 0,03859333 0,04811168 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,03859333 0,04808677 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,03859333 0,04806188 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,03859333 0,04803702 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,03977571 0,04948313 ! post-embryonic development GO:0009791 69 33 0,000 0,03977571 0,04945756 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,03977571 0,04943201 ! protein targeting to membrane GO:0006612 68 33 0,000 0,03977571 0,04940649 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,03977571 0,049381 ! ceramide metabolic process GO:0006672 64 33 0,000 0,03977571 0,04935553 ! formation of primary germ layer GO:0001704 72 33 0,000 0,03977571 0,04933009 ! cell fate specification GO:0001708 52 33 0,000 0,03977571 0,04930467 ! sterol transport GO:0015918 57 33 0,000 0,03977571 0,04927928 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,03977571 0,04925392 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,03977571 0,04922858 ! adult locomotory behavior GO:0008344 59 33 0,000 0,03977571 0,04920327 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,03977571 0,04917799 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,03977571 0,04915273 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,04095668 0,05058613 ! glial cell differentiation GO:0010001 63 34 0,000 0,04095668 0,05056018 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,04095668 0,05053425 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,04095668 0,05050835 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,04095668 0,05048247 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,04095668 0,05045662 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,04095668 0,0504308 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,04095668 0,050405 ! mismatch repair GO:0006298 46 34 0,000 0,04095668 0,05037923 ! spermatid development GO:0007286 63 34 0,000 0,04095668 0,05035349 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,04095668 0,05032777 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,04095668 0,05030208 ! placenta development GO:0001890 53 34 0,000 0,04095668 0,05027642 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,04095668 0,05025078 ! regulation of muscle development GO:0048634 70 35 0,000 0,04213624 0,05167166 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,04213624 0,05164534 ! negative regulation of secretion GO:0051048 63 35 0,000 0,04213624 0,05161904 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,04213624 0,05159277 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,04213624 0,05156653 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,04213624 0,05154031 ! odontogenesis GO:0042476 66 35 0,000 0,04213624 0,05151412 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,04213624 0,05148796 ! female gonad development GO:0008585 58 35 0,000 0,04213624 0,05146183 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,04213624 0,05143572 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,04213624 0,05140963 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,04213624 0,05138358 ! cytokine production GO:0001816 59 35 0,000 0,04213624 0,05135755 ! neural tube formation GO:0001841 67 35 0,000 0,04213624 0,05133154 ! vesicle localization GO:0051648 64 35 0,000 0,04213624 0,05130556 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,04331439 0,05271341 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,04331439 0,05268676 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,04331439 0,05266014 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,04331439 0,05263354 ! cell junction organization GO:0034330 86 36 0,000 0,04331439 0,05260697 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,04331439 0,05258043 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,04331439 0,05255391 ! positive regulation of cell development GO:0010720 80 36 0,000 0,04331439 0,05252743 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,04331439 0,05250096 ! regulation of proteolysis GO:0030162 72 36 0,000 0,04331439 0,05247453 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,04331439 0,05244812 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,04331439 0,05242174 ! aerobic respiration GO:0009060 55 36 0,000 0,04331439 0,05239538 ! embryonic organ development GO:0048568 57 36 0,000 0,04331439 0,05236905 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,04331439 0,05234275 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,04331439 0,05231647 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,04449112 0,05371081 ! meiosis I GO:0007127 65 37 0,000 0,04449112 0,05368387 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,04449112 0,05365696 ! sister chromatid segregation GO:0000819 58 37 0,000 0,04449112 0,05363008 ! actomyosin structure organization GO:0031032 62 37 0,000 0,04449112 0,05360322 ! organic anion transport GO:0015711 68 37 0,000 0,04449112 0,0535764 ! tissue remodeling GO:0048771 76 37 0,000 0,04449112 0,05354959 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,04449112 0,05352282 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,04449112 0,05349607 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,04449112 0,05346935 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,04449112 0,05344265 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,04449112 0,05341599 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,04449112 0,05338935 ! glycogen metabolic process GO:0005977 61 37 0,000 0,04449112 0,05336273 ! pigment metabolic process GO:0042440 80 37 0,000 0,04449112 0,05333614 ! spermatid differentiation GO:0048515 66 37 0,000 0,04449112 0,05330958 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,04449112 0,05328305 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,04566645 0,05466342 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,04566645 0,05463624 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,04566645 0,05460908 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,04566645 0,05458195 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,04566645 0,05455485 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,04566645 0,05452778 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,04566645 0,05450073 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,04566645 0,05447371 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,04566645 0,05444672 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,04566645 0,05441975 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,04566645 0,05439281 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,04566645 0,0543659 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,04566645 0,05433901 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,04566645 0,05431215 ! glucan metabolic process GO:0044042 62 38 0,000 0,04566645 0,05428531 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,04684037 0,0556533 ! mammary gland development GO:0030879 86 39 0,000 0,04684037 0,05562583 ! learning GO:0007612 77 39 0,000 0,04684037 0,05559838 ! ear morphogenesis GO:0042471 60 39 0,000 0,04684037 0,05557097 ! organic ether metabolic process GO:0018904 55 39 0,000 0,04684037 0,05554358 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,04684037 0,05551622 ! segmentation GO:0035282 67 39 0,000 0,04684037 0,05548889 ! ion transmembrane transport GO:0034220 66 39 0,000 0,04684037 0,05546158 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,04684037 0,0554343 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,04684037 0,05540704 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,04684037 0,05537982 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,04684037 0,05535262 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,04801288 0,05671036 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,04801288 0,05668253 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,04801288 0,05665473 ! feeding behavior GO:0007631 59 40 0,000 0,04801288 0,05662696 ! negative regulation of binding GO:0051100 72 40 0,000 0,04801288 0,05659921 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,04801288 0,0565715 ! mesenchymal cell development GO:0014031 87 40 0,000 0,04801288 0,05654381 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,04801288 0,05651614 ! maintenance of protein location GO:0045185 91 40 0,000 0,04801288 0,05648851 ! cytokinesis GO:0000910 72 40 0,000 0,04801288 0,0564609 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,04918399 0,05780981 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,04918399 0,05778159 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,04918399 0,05775339 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,04918399 0,05772522 ! gliogenesis GO:0042063 88 41 0,000 0,04918399 0,05769707 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,04918399 0,05766895 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,04918399 0,05764086 ! T cell differentiation GO:0030217 81 41 0,000 0,04918399 0,0576128 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,04918399 0,05758476 ! female gamete generation GO:0007292 61 41 0,000 0,04918399 0,05755676 ! polyol metabolic process GO:0019751 66 41 0,000 0,04918399 0,05752878 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,04918399 0,05750082 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,0503537 0,05883973 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,0503537 0,05881117 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,0503537 0,05878264 ! regulation of tube size GO:0035150 71 42 0,000 0,0503537 0,05875413 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,0503537 0,05872565 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,0503537 0,0586972 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,0503537 0,05866877 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,0503537 0,05864037 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,0503537 0,058612 ! neuron migration GO:0001764 79 42 0,000 0,0503537 0,05858366 ! regulation of protein secretion GO:0050708 71 42 0,000 0,0503537 0,05855535 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,0503537 0,05852706 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,05152201 0,05985609 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,05152201 0,0598272 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,05152201 0,05979834 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,05152201 0,05976951 ! glucose transport GO:0015758 65 43 0,000 0,05152201 0,05974071 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,05152201 0,05971193 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,05152201 0,05968318 ! neural tube development GO:0021915 77 43 0,000 0,05152201 0,05965446 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,05152201 0,05962577 ! striated muscle contraction GO:0006941 77 43 0,000 0,05152201 0,0595971 ! phagocytosis GO:0006909 90 43 0,000 0,05152201 0,05956846 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,05152201 0,05953985 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,05268893 0,06085912 ! hexose transport GO:0008645 67 44 0,000 0,05268893 0,06082992 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,05268893 0,06080075 ! male sex differentiation GO:0046661 76 44 0,000 0,05268893 0,0607716 ! double-strand break repair GO:0006302 81 44 0,000 0,05268893 0,06074248 ! biopolymer methylation GO:0043414 84 44 0,000 0,05268893 0,06071339 ! B cell differentiation GO:0030183 107 44 0,000 0,05268893 0,06068432 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,05268893 0,06065529 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,05268893 0,06062628 ! developmental growth GO:0048589 82 44 0,000 0,05268893 0,0605973 ! maintenance of location in cell GO:0051651 97 44 0,000 0,05268893 0,06056835 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,05385444 0,0618786 ! glycolysis GO:0006096 65 45 0,000 0,05385444 0,06184906 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,05385444 0,06181955 ! leukocyte migration GO:0050900 68 45 0,000 0,05385444 0,06179007 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,05385444 0,06176062 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,05385444 0,0617312 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,05385444 0,0617018 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,05385444 0,06167243 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,05385444 0,06164309 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,05385444 0,06161378 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,05385444 0,0615845 ! cell growth GO:0016049 84 45 0,000 0,05385444 0,06155524 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,05501856 0,06285596 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,05501856 0,06282613 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,05501856 0,06279632 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,05501856 0,06276655 ! pigmentation GO:0043473 100 46 0,000 0,05501856 0,0627368 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,05501856 0,06270708 ! positive regulation of defense response GO:0031349 76 47 0,000 0,05618128 0,06400197 ! endosome transport GO:0016197 108 47 0,000 0,05618128 0,06397168 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,05618128 0,06394142 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,05618128 0,06391119 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,05618128 0,06388099 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,05618128 0,06385081 ! JNK cascade GO:0007254 91 47 0,000 0,05618128 0,06382067 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,05618128 0,06379055 ! methylation GO:0032259 90 47 0,000 0,05618128 0,06376046 ! protein homooligomerization GO:0051260 76 47 0,000 0,05618128 0,0637304 ! mitochondrial transport GO:0006839 82 48 0,000 0,05734262 0,06501712 ! Notch signaling pathway GO:0007219 96 48 0,000 0,05734262 0,0649865 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,05734262 0,0649559 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,05734262 0,06492533 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,05734262 0,0648948 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,05734262 0,06486429 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,05734262 0,0648338 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,05850256 0,06611421 ! regulation of action potential GO:0001508 95 49 0,000 0,05850256 0,06608317 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,05850256 0,06605216 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,05850256 0,06602118 ! regulation of ion transport GO:0043269 77 49 0,000 0,05850256 0,06599023 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,05850256 0,06595931 ! peptide metabolic process GO:0006518 76 49 0,000 0,05850256 0,06592841 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,05850256 0,06589755 ! endocrine system development GO:0035270 104 49 0,000 0,05850256 0,06586671 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,05850256 0,0658359 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,05850256 0,06580512 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,05850256 0,06577437 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,05850256 0,06574365 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,05966111 0,0670143 ! neuromuscular process GO:0050905 99 50 0,000 0,05966111 0,06698303 ! regulation of ossification GO:0030278 117 50 0,000 0,05966111 0,06695179 ! inner ear development GO:0048839 79 50 0,000 0,05966111 0,06692058 ! histone modification GO:0016570 91 50 0,000 0,05966111 0,06688939 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,05966111 0,06685824 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,05966111 0,06682711 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,05966111 0,06679602 ! positive regulation of binding GO:0051099 78 51 0,000 0,06081828 0,0680599 ! viral infectious cycle GO:0019058 99 51 0,000 0,06081828 0,06802826 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,06081828 0,06799665 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,06081828 0,06796506 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,06081828 0,06793351 ! excretion GO:0007588 83 51 0,000 0,06081828 0,06790199 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,06081828 0,06787049 ! chromatin remodeling GO:0006338 109 51 0,000 0,06081828 0,06783903 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,06081828 0,06780759 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,06081828 0,06777619 ! vesicle organization GO:0016050 107 51 0,000 0,06081828 0,06774481 ! regulation of cell shape GO:0008360 125 51 0,000 0,06081828 0,06771346 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,06081828 0,06768214 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,06197406 0,06893647 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,06197406 0,06890462 ! membrane fusion GO:0006944 110 52 0,000 0,06197406 0,06887279 ! covalent chromatin modification GO:0016569 101 52 0,000 0,06197406 0,06884099 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,06197406 0,06880923 ! amino acid activation GO:0043038 92 52 0,000 0,06197406 0,06877749 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,06197406 0,06874578 ! synapse organization GO:0050808 85 52 0,000 0,06197406 0,0687141 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,06312846 0,0699618 ! RNA catabolic process GO:0006401 93 53 0,000 0,06312846 0,06992959 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,06312846 0,06989741 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,06312846 0,06986526 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,06312846 0,06983314 ! cell maturation GO:0048469 100 53 0,000 0,06312846 0,06980105 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,06312846 0,06976898 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,06312846 0,06973695 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,06428148 0,07097808 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,06428148 0,07094552 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,06428148 0,07091299 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,06428148 0,07088049 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,06428148 0,07084802 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,06428148 0,07081558 ! chloride transport GO:0006821 90 55 0,000 0,06543311 0,07205129 ! glucose catabolic process GO:0006007 82 55 0,000 0,06543311 0,07201833 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,06543311 0,0719854 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,06543311 0,0719525 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,06543311 0,07191963 ! aging GO:0007568 103 55 0,000 0,06543311 0,07188679 ! gastrulation GO:0007369 112 55 0,000 0,06543311 0,07185398 ! heart morphogenesis GO:0003007 97 55 0,000 0,06543311 0,0718212 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,06543311 0,07178845 ! RNA elongation GO:0006354 79 55 0,000 0,06543311 0,07175573 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,06543311 0,07172303 ! regulation of actin filament length GO:0030832 105 56 0,000 0,06658336 0,07295063 ! sensory perception of smell GO:0007608 80 56 0,000 0,06658336 0,07291742 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,06658336 0,07288425 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,06658336 0,0728511 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,06658336 0,07281799 ! regulation of DNA replication GO:0006275 101 56 0,000 0,06658336 0,0727849 ! proton transport GO:0015992 94 56 0,000 0,06658336 0,07275185 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,06773224 0,07397357 ! muscle fiber development GO:0048747 112 57 0,000 0,06773224 0,07394001 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,06773224 0,07390647 ! lipid modification GO:0030258 97 57 0,000 0,06773224 0,07387297 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,06773224 0,0738395 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,06773224 0,07380606 ! maintenance of location GO:0051235 118 57 0,000 0,06773224 0,07377265 ! hydrogen transport GO:0006818 97 58 0,000 0,06887974 0,07498854 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,06887974 0,07495462 ! regulation of endocytosis GO:0030100 91 58 0,000 0,06887974 0,07492073 ! adult behavior GO:0030534 99 58 0,000 0,06887974 0,07488688 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,06887974 0,07485306 ! positive regulation of secretion GO:0051047 95 59 0,000 0,07002587 0,07606422 ! regulation of cellular component size GO:0032535 109 59 0,000 0,07002587 0,0760299 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,07002587 0,0759956 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,07002587 0,07596134 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,07002587 0,07592711 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,07002587 0,0758929 ! establishment of organelle localization GO:0051656 109 59 0,000 0,07002587 0,07585873 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,07117063 0,07706414 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,07117063 0,07702948 ! regulation of heart contraction GO:0008016 110 60 0,000 0,07117063 0,07699484 ! camera-type eye development GO:0043010 116 60 0,000 0,07117063 0,07696024 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,07117063 0,07692566 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,07117063 0,07689112 ! kidney development GO:0001822 122 60 0,000 0,07117063 0,07685661 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,07231401 0,07805631 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,07231401 0,0780213 ! mesoderm development GO:0007498 119 61 0,000 0,07231401 0,07798633 ! tRNA processing GO:0008033 89 61 0,000 0,07231401 0,07795139 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,07231401 0,07791648 ! ear development GO:0043583 103 62 0,000 0,07345603 0,07911155 ! viral reproductive process GO:0022415 126 62 0,000 0,07345603 0,07907615 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,07345603 0,07904079 ! gonad development GO:0008406 98 62 0,000 0,07345603 0,07900545 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,07345603 0,07897015 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,07459667 0,0801606 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,07459667 0,08012482 ! detection of external stimulus GO:0009581 91 63 0,000 0,07459667 0,08008906 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,07459667 0,08005334 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,07573595 0,08123972 ! cell redox homeostasis GO:0045454 102 64 0,000 0,07573595 0,08120352 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,07573595 0,08116735 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,07573595 0,08113121 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,07573595 0,0810951 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,07573595 0,08105903 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,07687387 0,08224034 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,07687387 0,08220379 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,07687387 0,08216727 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,07687387 0,08213078 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,07687387 0,08209433 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,07801042 0,0832711 ! actin filament organization GO:0007015 148 66 0,000 0,07801042 0,08323418 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,07801042 0,08319728 ! extracellular matrix organization GO:0030198 133 66 0,000 0,07801042 0,08316042 ! secondary metabolic process GO:0019748 116 66 0,000 0,07801042 0,08312359 ! developmental maturation GO:0021700 116 66 0,000 0,07801042 0,08308679 ! cell projection assembly GO:0030031 120 66 0,000 0,07801042 0,08305003 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,07914561 0,08422129 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,07914561 0,08418406 ! activation of MAPK activity GO:0000187 115 67 0,000 0,07914561 0,08414686 ! lung development GO:0030324 144 67 0,000 0,07914561 0,08410969 ! chromosome segregation GO:0007059 113 67 0,000 0,07914561 0,08407255 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,07914561 0,08403545 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,07914561 0,08399838 ! hexose catabolic process GO:0019320 104 67 0,000 0,07914561 0,08396135 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,07914561 0,08392434 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,07914561 0,08388737 ! adaptive immune response GO:0002250 119 67 0,000 0,07914561 0,08385043 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,07914561 0,08381353 ! amino acid transport GO:0006865 125 68 0,000 0,08027944 0,08497683 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,08027944 0,08493946 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,08027944 0,08490212 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 0,000 0,08027944 0,08486482 ! regulation of lipase activity GO:0060191 130 68 0,000 0,08027944 0,08482755 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,08027944 0,08479031 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,08141191 0,08594869 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,08141191 0,08591099 ! urogenital system development GO:0001655 137 69 0,000 0,08141191 0,08587333 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,08141191 0,0858357 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,08141191 0,0857981 ! antigen processing and presentation GO:0019882 104 69 0,000 0,08141191 0,08576054 ! appendage morphogenesis GO:0035107 135 70 0,000 0,08254303 0,08691402 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,08254303 0,086876 ! amine catabolic process GO:0009310 117 71 0,000 0,08367279 0,08802655 ! reproductive structure development GO:0048608 113 71 0,000 0,08367279 0,08798808 ! appendage development GO:0048736 136 71 0,000 0,08367279 0,08794964 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,08367279 0,08791124 ! B cell activation GO:0042113 160 71 0,000 0,08367279 0,08787286 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,08367279 0,08783452 ! regulation of immune effector process GO:0002697 137 71 0,000 0,08367279 0,08779622 ! acute inflammatory response GO:0002526 113 72 0,000 0,0848012 0,08894145 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,0848012 0,08890269 ! carbohydrate transport GO:0008643 110 72 0,000 0,0848012 0,08886397 ! respiratory system development GO:0060541 153 72 0,000 0,0848012 0,08882528 ! learning or memory GO:0007611 147 73 0,000 0,08592825 0,08996665 ! regulation of blood pressure GO:0008217 125 73 0,000 0,08592825 0,08992752 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,08592825 0,08988842 ! axon guidance GO:0007411 139 73 0,000 0,08592825 0,08984936 ! fertilization GO:0009566 90 73 0,000 0,08592825 0,08981033 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,08705395 0,09094738 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,08705395 0,09090791 ! neurotransmitter transport GO:0006836 123 74 0,000 0,08705395 0,09086847 ! meiosis GO:0007126 121 74 0,000 0,08705395 0,09082906 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,08705395 0,09078969 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,08705395 0,09075035 ! eye development GO:0001654 143 74 0,000 0,08705395 0,09071105 ! organelle localization GO:0051640 136 74 0,000 0,08705395 0,09067178 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,08817831 0,09180312 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,08817831 0,09176341 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,08817831 0,09172374 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,08817831 0,0916841 ! meiotic cell cycle GO:0051321 122 75 0,000 0,08817831 0,0916445 ! rhythmic process GO:0048511 128 75 0,000 0,08817831 0,09160493 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,08817831 0,09156539 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,08930132 0,09269153 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,08930132 0,09265156 ! defense response to bacterium GO:0042742 89 76 0,000 0,08930132 0,09261162 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,08930132 0,09257172 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,08930132 0,09253186 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,09042298 0,09365376 ! blood coagulation GO:0007596 146 78 0,000 0,0915433 0,09477331 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,0915433 0,09473255 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,0915433 0,09469182 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,0915433 0,09465113 ! protein oligomerization GO:0051259 139 78 0,000 0,0915433 0,09461047 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,09266227 0,09572582 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,09266227 0,09568473 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,09266227 0,09564368 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,09266227 0,09560267 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,09377991 0,0967143 ! muscle cell differentiation GO:0042692 159 80 0,000 0,09377991 0,09667286 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,09377991 0,09663146 ! inorganic anion transport GO:0015698 138 80 0,000 0,09377991 0,09659009 ! T cell activation GO:0042110 168 81 0,000 0,0948962 0,09769801 ! response to hypoxia GO:0001666 171 81 0,000 0,0948962 0,09765623 ! digestion GO:0007586 112 81 0,000 0,0948962 0,09761448 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,0948962 0,09757276 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,0948962 0,09753108 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,0948962 0,09748944 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,09601116 0,09859276 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,09601116 0,0985507 ! response to drug GO:0042493 143 82 0,000 0,09601116 0,09850868 ! response to nutrient GO:0007584 125 82 0,000 0,09601116 0,09846669 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,09601116 0,09842473 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,09601116 0,09838281 ! response to oxygen levels GO:0070482 176 83 0,000 0,09712478 0,09948157 ! regulation of lyase activity GO:0051339 160 83 0,000 0,09712478 0,09943924 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,09823706 0,10053525 ! hemostasis GO:0007599 158 84 0,000 0,09823706 0,10049251 ! negative regulation of transport GO:0051051 153 84 0,000 0,09823706 0,1004498 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,09823706 0,10040713 ! nucleosome assembly GO:0006334 122 85 0,000 0,09934802 0,1014995 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,09934802 0,10145642 ! amine biosynthetic process GO:0009309 138 86 0,000 0,10045764 0,10254606 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,10045764 0,10250258 ! chromatin assembly GO:0031497 124 86 0,000 0,10045764 0,10245912 ! tube morphogenesis GO:0035239 176 86 0,000 0,10045764 0,10241571 ! alcohol catabolic process GO:0046164 130 86 0,000 0,10045764 0,10237233 ! amine transport GO:0015837 155 86 0,000 0,10045764 0,10232899 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,10156593 0,10341414 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,10156593 0,1033704 ! regulation of protein transport GO:0051223 154 87 0,000 0,10156593 0,10332669 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 0,000 0,10267289 0,10440869 ! gland development GO:0048732 206 88 0,000 0,10267289 0,10436458 ! regulation of neurological system process GO:0031644 148 88 0,000 0,10267289 0,10432051 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,10267289 0,10427648 ! cellular defense response GO:0006968 114 89 0,000 0,10377852 0,10535491 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,10377852 0,10531047 ! ossification GO:0001503 188 90 0,000 0,10488283 0,10638621 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,10488283 0,10634138 ! sex differentiation GO:0007548 145 90 0,000 0,10488283 0,10629659 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,10488283 0,10625183 ! bone development GO:0060348 189 91 0,000 0,10598582 0,10732402 ! sterol metabolic process GO:0016125 152 91 0,000 0,10598582 0,10727887 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,10598582 0,10723376 ! regulation of defense response GO:0031347 149 92 0,000 0,10708748 0,10830285 ! nucleosome organization GO:0034728 138 92 0,000 0,10708748 0,10825734 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,10708748 0,10821188 ! vitamin metabolic process GO:0006766 139 92 0,000 0,10708748 0,10816645 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,10818782 0,10923202 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,10818782 0,1091862 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,10818782 0,10914042 ! regulation of membrane potential GO:0042391 164 93 0,000 0,10818782 0,10909468 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,10818782 0,10904897 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,10928684 0,11011061 ! female pregnancy GO:0007565 164 94 0,000 0,10928684 0,11006452 ! transcription initiation GO:0006352 153 94 0,000 0,10928684 0,11001847 ! regulation of T cell activation GO:0050863 158 94 0,000 0,10928684 0,10997246 ! forebrain development GO:0030900 188 95 0,000 0,11038455 0,11103061 ! leukocyte differentiation GO:0002521 202 96 0,000 0,11148094 0,11208656 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,11148094 0,11203974 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,11148094 0,11199296 ! detection of stimulus GO:0051606 151 96 0,000 0,11148094 0,11194622 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,11257601 0,1129987 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,11257601 0,11295158 ! protein ubiquitination GO:0016567 217 97 0,000 0,11257601 0,11290449 ! hormone metabolic process GO:0042445 157 97 0,000 0,11257601 0,11285745 ! regulation of protein localization GO:0032880 176 97 0,000 0,11257601 0,11281045 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,11366977 0,11385906 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,11366977 0,11381168 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,11476222 0,1148577 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,11476222 0,11480994 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,11476222 0,11476222 GO:0060538|skeletal muscle organ development,