pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/1022-0-real-Parker_GPL1390-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL1390.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 51 50 6,000 1,092E-15 3,901E-12 ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 2,000 1,73E-08 3,089E-05 ! G1/S transition of mitotic cell cycle GO:0000082 47 46 3,000 2,7E-08 3,214E-05 ! cyclin-dependent protein kinase regulator activity GO:0016538 11 11 2,000 5,091E-08 4,545E-05 ! protein kinase regulator activity GO:0019887 64 64 3,000 1,044E-07 7,457E-05 ! protein serine/threonine kinase inhibitor activity GO:0030291 14 14 2,000 1,122E-07 6,677E-05 ! kinase regulator activity GO:0019207 77 77 3,000 2,213E-07 1,129E-04 ! interphase of mitotic cell cycle GO:0051329 84 82 3,000 2,854E-07 1,274E-04 GO:0051325|interphase, ! protein kinase inhibitor activity GO:0004860 28 28 2,000 1,004E-06 3,983E-04 ! kinase inhibitor activity GO:0019210 30 30 2,000 1,243E-06 4,439E-04 ! induction of apoptosis by intracellular signals GO:0008629 46 43 2,000 3,759E-06 1,22E-03 ! negative regulation of protein ubiquitination GO:0031397 5 5 1,000 5,061E-06 1,506E-03 ! response to UV GO:0009411 50 49 2,000 5,598E-06 1,538E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 7,589E-06 1,936E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 7 7 1,000 1,062E-05 2,528E-03 GO:0010921|regulation of phosphatase activity, ! regulation of focal adhesion formation GO:0051893 9 7 1,000 1,062E-05 2,37E-03 ! negative regulation of protein kinase activity GO:0006469 67 61 2,000 1,088E-05 2,286E-03 ! negative regulation of kinase activity GO:0033673 68 62 2,000 1,143E-05 2,268E-03 ! negative regulation of transferase activity GO:0051348 71 65 2,000 1,318E-05 2,478E-03 ! keratinocyte proliferation GO:0043616 8 8 1,000 1,415E-05 2,527E-03 ! T cell homeostasis GO:0043029 9 8 1,000 1,415E-05 2,407E-03 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 8 8 1,000 1,415E-05 2,297E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 9 9 1,000 1,819E-05 2,824E-03 ! middle ear morphogenesis GO:0042474 9 9 1,000 1,819E-05 2,707E-03 ! positive regulation of Rho GTPase activity GO:0032321 9 9 1,000 1,819E-05 2,598E-03 ! regulation of dephosphorylation GO:0035303 12 10 1,000 2,273E-05 3,122E-03 ! regulation of stress fiber formation GO:0051492 13 10 1,000 2,273E-05 3,006E-03 ! thymus development GO:0048538 12 11 1,000 2,777E-05 3,541E-03 ! regulation of actin filament bundle formation GO:0032231 14 11 1,000 2,777E-05 3,419E-03 ! positive regulation of B cell proliferation GO:0030890 15 11 1,000 2,777E-05 3,305E-03 ! cell cycle arrest GO:0007050 92 87 2,000 3,171E-05 3,653E-03 ! positive regulation of Ras GTPase activity GO:0032320 12 12 1,000 3,331E-05 3,717E-03 ! lymphocyte homeostasis GO:0002260 14 12 1,000 3,331E-05 3,604E-03 ! negative regulation of caspase activity GO:0043154 12 12 1,000 3,331E-05 3,498E-03 ! protein tyrosine phosphatase activity GO:0004725 104 92 2,000 3,749E-05 3,825E-03 ! positive regulation of GTPase activity GO:0043547 14 13 1,000 3,935E-05 3,903E-03 ! positive regulation of cell growth GO:0030307 13 13 1,000 3,935E-05 3,798E-03 ! regulation of protein ubiquitination GO:0031396 13 13 1,000 3,935E-05 3,698E-03 ! release of cytochrome c from mitochondria GO:0001836 14 14 1,000 4,589E-05 4,202E-03 ! regulation of B cell proliferation GO:0030888 18 14 1,000 4,589E-05 4,097E-03 ! skin development GO:0043588 16 15 1,000 5,293E-05 4,61E-03 ! negative regulation of peptidase activity GO:0010466 16 15 1,000 5,293E-05 4,5E-03 ! positive regulation of cell size GO:0045793 16 16 1,000 6,046E-05 5,021E-03 ! regulation of Rho GTPase activity GO:0032319 17 17 1,000 6,85E-05 5,559E-03 ! G2/M transition of mitotic cell cycle GO:0000086 17 17 1,000 6,85E-05 5,436E-03 ! chaperone binding GO:0051087 18 18 1,000 7,703E-05 5,98E-03 ! negative regulation of translation GO:0017148 20 18 1,000 7,703E-05 5,852E-03 ! cellular response to unfolded protein GO:0034620 21 19 1,000 8,605E-05 6,402E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 21 20 1,000 9,558E-05 6,965E-03 ! leukocyte homeostasis GO:0001776 22 20 1,000 9,558E-05 6,826E-03 ! regulation of cell-matrix adhesion GO:0001952 22 20 1,000 9,558E-05 6,692E-03 GO:0010810|regulation of cell-substrate adhesion, ! growth cone GO:0030426 22 21 1,000 1,056E-04 7,251E-03 ! apoptotic mitochondrial changes GO:0008637 21 21 1,000 1,056E-04 7,115E-03 ! positive regulation of fibroblast proliferation GO:0048146 22 21 1,000 1,056E-04 6,983E-03 ! site of polarized growth GO:0030427 23 22 1,000 1,161E-04 7,538E-03 ! positive regulation of cell adhesion GO:0045785 23 22 1,000 1,161E-04 7,404E-03 ! positive regulation of B cell activation GO:0050871 26 22 1,000 1,161E-04 7,274E-03 ! negative regulation of phosphorylation GO:0042326 26 22 1,000 1,161E-04 7,149E-03 ! androgen receptor binding GO:0050681 23 23 1,000 1,271E-04 7,694E-03 ! negative regulation of phosphorus metabolic process GO:0010563 27 23 1,000 1,271E-04 7,565E-03 GO:0045936|negative regulation of phosphate metabolic process, ! nucleotide-excision repair, DNA damage removal GO:0000718 24 23 1,000 1,271E-04 7,441E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 24 24 1,000 1,386E-04 7,984E-03 ! regulation of fibroblast proliferation GO:0048145 25 24 1,000 1,386E-04 7,857E-03 ! negative regulation of protein modification process GO:0031400 28 24 1,000 1,386E-04 7,734E-03 ! RNA export from nucleus GO:0006405 27 25 1,000 1,506E-04 8,274E-03 ! actin filament GO:0005884 28 25 1,000 1,506E-04 8,149E-03 ! cyclin-dependent protein kinase activity GO:0004693 26 25 1,000 1,506E-04 8,027E-03 ! fat cell differentiation GO:0045444 26 26 1,000 1,631E-04 8,564E-03 ! response to endoplasmic reticulum stress GO:0034976 29 26 1,000 1,631E-04 8,44E-03 ! cellular response to extracellular stimulus GO:0031668 27 26 1,000 1,631E-04 8,32E-03 ! ER-nuclear signaling pathway GO:0006984 31 28 1,000 1,895E-04 9,532E-03 ! negative regulation of hydrolase activity GO:0051346 32 30 1,000 2,179E-04 0,01080871 ! regulation of Wnt receptor signaling pathway GO:0030111 35 32 1,000 2,483E-04 0,01214569 ! regulation of B cell activation GO:0050864 36 32 1,000 2,483E-04 0,01198156 ! steroid hormone receptor binding GO:0035258 33 33 1,000 2,642E-04 0,01257937 ! androgen receptor signaling pathway GO:0030521 34 33 1,000 2,642E-04 0,01241386 ! metanephros development GO:0001656 35 35 1,000 2,975E-04 0,01379618 ! response to calcium ion GO:0051592 39 35 1,000 2,975E-04 0,0136193 ! positive regulation of leukocyte proliferation GO:0070665 40 36 1,000 3,149E-04 0,0142321 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! ear morphogenesis GO:0042471 39 38 1,000 3,51E-04 0,01566993 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 40 38 1,000 3,51E-04 0,01547648 ! positive regulation of cell cycle GO:0045787 39 39 1,000 3,699E-04 0,01610754 ! nuclear export GO:0051168 42 40 1,000 3,892E-04 0,0167442 ! protein serine/threonine phosphatase activity GO:0004722 42 40 1,000 3,892E-04 0,01654487 ! response to insulin stimulus GO:0032868 45 40 1,000 3,892E-04 0,01635022 ! embryonic skeletal system morphogenesis GO:0048704 42 41 1,000 4,09E-04 0,01698191 ! positive regulation of growth GO:0045927 42 42 1,000 4,292E-04 0,01761887 ! keratinocyte differentiation GO:0030216 46 43 1,000 4,5E-04 0,01826091 ! regulation of mast cell proliferation GO:0070666 48 44 1,000 4,712E-04 0,01890782 ! RNA elongation from RNA polymerase II promoter GO:0006368 48 46 1,000 5,152E-04 0,02044016 ! regulation of leukocyte proliferation GO:0070663 50 46 1,000 5,152E-04 0,02021554 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epidermal cell differentiation GO:0009913 51 48 1,000 5,61E-04 0,02177479 ! protein N-terminus binding GO:0047485 51 48 1,000 5,61E-04 0,02154065 ! lamellipodium GO:0030027 53 49 1,000 5,846E-04 0,02220932 ! RNA elongation GO:0006354 51 49 1,000 5,846E-04 0,02197554 ! DNA damage response, signal transduction GO:0042770 58 52 1,000 6,584E-04 0,02449048 ! positive regulation of protein amino acid phosphorylation GO:0001934 54 52 1,000 6,584E-04 0,024238 ! embryonic skeletal system development GO:0048706 54 53 1,000 6,839E-04 0,02492133 ! DNA catabolic process GO:0006308 55 54 1,000 7,099E-04 0,025608 ! response to peptide hormone stimulus GO:0043434 60 55 1,000 7,364E-04 0,02629788 ! nucleotide-excision repair GO:0006289 58 55 1,000 7,364E-04 0,02603751 ! ear development GO:0043583 60 57 1,000 7,908E-04 0,02768683 ! kidney development GO:0001822 60 57 1,000 7,908E-04 0,02741802 ! positive regulation of phosphorylation GO:0042327 59 57 1,000 7,908E-04 0,02715439 ! steroid hormone receptor signaling pathway GO:0030518 58 57 1,000 7,908E-04 0,02689577 ! positive regulation of phosphorus metabolic process GO:0010562 61 58 1,000 8,187E-04 0,0275823 GO:0045937|positive regulation of phosphate metabolic process, ! homeostasis of number of cells GO:0048872 62 58 1,000 8,187E-04 0,02732453 ! intracellular receptor-mediated signaling pathway GO:0030522 64 63 1,000 9,654E-04 0,0319196 ! negative regulation of cell growth GO:0030308 68 65 1,000 1,027E-03 0,03365596 ! response to metal ion GO:0010038 69 65 1,000 1,027E-03 0,03335 ! positive regulation of protein modification process GO:0031401 69 65 1,000 1,027E-03 0,03304955 ! skeletal system morphogenesis GO:0048705 66 65 1,000 1,027E-03 0,03275446 ! urogenital system development GO:0001655 69 66 1,000 1,059E-03 0,03346549 ! response to unfolded protein GO:0006986 68 66 1,000 1,059E-03 0,03317193 ! negative regulation of cell size GO:0045792 70 67 1,000 1,091E-03 0,03388147 ! positive regulation of lymphocyte activation GO:0051251 72 67 1,000 1,091E-03 0,03358939 ! regulation of caspase activity GO:0043281 70 67 1,000 1,091E-03 0,0333023 ! nuclear hormone receptor binding GO:0035257 68 67 1,000 1,091E-03 0,03302008 ! transcription initiation from RNA polymerase II promoter GO:0006367 71 67 1,000 1,091E-03 0,0327426 ! protein import into nucleus GO:0006606 72 68 1,000 1,124E-03 0,03344005 ! regulation of actin cytoskeleton organization GO:0032956 74 68 1,000 1,124E-03 0,03316369 ! regulation of endopeptidase activity GO:0052548 72 69 1,000 1,157E-03 0,0338599 ! nuclear import GO:0051170 74 70 1,000 1,19E-03 0,03455832 ! response to inorganic substance GO:0010035 74 70 1,000 1,19E-03 0,03427963 ! cell cortex GO:0005938 74 70 1,000 1,19E-03 0,03400539 ! regulation of actin filament-based process GO:0032970 77 71 1,000 1,224E-03 0,03469921 ! response to protein stimulus GO:0051789 74 72 1,000 1,259E-03 0,03539517 ! hormone receptor binding GO:0051427 75 73 1,000 1,294E-03 0,03609319 ! regulation of peptidase activity GO:0052547 78 74 1,000 1,329E-03 0,03679323 ! protein localization in nucleus GO:0034504 78 74 1,000 1,329E-03 0,0365102 ! regulation of Rho protein signal transduction GO:0035023 79 74 1,000 1,329E-03 0,0362315 ! establishment of RNA localization GO:0051236 78 75 1,000 1,365E-03 0,0369271 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! positive regulation of cell activation GO:0050867 80 75 1,000 1,365E-03 0,03664945 GO:0002696|positive regulation of leukocyte activation, ! RNA localization GO:0006403 80 77 1,000 1,438E-03 0,03832409 ! regulation of cell adhesion GO:0030155 82 78 1,000 1,475E-03 0,03902536 ! negative regulation of growth GO:0045926 84 80 1,000 1,551E-03 0,0407305 ! regulation of Ras GTPase activity GO:0032318 84 80 1,000 1,551E-03 0,0404332 ! protein kinase binding GO:0019901 89 80 1,000 1,551E-03 0,0401402 ! transcription initiation GO:0006352 86 82 1,000 1,629E-03 0,04184772 ! mitochondrion organization GO:0007005 86 83 1,000 1,668E-03 0,04255737 ! cell leading edge GO:0031252 90 83 1,000 1,668E-03 0,04225554 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 92 89 1,000 1,915E-03 0,04816524 ! in utero embryonic development GO:0001701 97 95 1,000 2,178E-03 0,05440056 ! regulation of lymphocyte activation GO:0051249 100 95 1,000 2,178E-03 0,05402278 ! regulation of GTPase activity GO:0043087 104 97 1,000 2,27E-03 0,05589965 ! protein C-terminus binding GO:0008022 106 99 1,000 2,363E-03 0,0577948 ! regulation of cellular component biogenesis GO:0044087 106 99 1,000 2,363E-03 0,05740164 ! kinase binding GO:0019900 108 99 1,000 2,363E-03 0,05701379 ! tRNA transcription GO:0009304 5 5 0,000 3,728E-03 0,08934207 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 5 5 0,000 3,728E-03 0,08874646 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 3,728E-03 0,08815873 ! benzene and derivative metabolic process GO:0042537 5 5 0,000 3,728E-03 0,08757874 ! response to oxygen radical GO:0000305 5 5 0,000 3,728E-03 0,08700633 ! positive regulation of axon extension GO:0045773 6 5 0,000 3,728E-03 0,08644135 ! negative regulation of bone resorption GO:0045779 5 5 0,000 3,728E-03 0,08588367 ! positive regulation of lipid biosynthetic process GO:0046889 5 5 0,000 3,728E-03 0,08533313 ! regulation of interferon-beta production GO:0032648 6 5 0,000 3,728E-03 0,08478961 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! sodium-independent organic anion transmembrane transporter activity GO:0015347 6 5 0,000 3,728E-03 0,08425297 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 3,728E-03 0,08372307 ! negative regulation of transmembrane transport GO:0034763 5 5 0,000 3,728E-03 0,0831998 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! hypothalamus development GO:0021854 5 5 0,000 3,728E-03 0,08268303 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 3,728E-03 0,08217264 ! N-terminal protein lipidation GO:0006498 5 5 0,000 3,728E-03 0,08166852 ! glycolipid transport GO:0046836 5 5 0,000 3,728E-03 0,08117054 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 5 5 0,000 3,728E-03 0,0806786 ! phosphoinositide 3-kinase binding GO:0043548 5 5 0,000 3,728E-03 0,08019258 ! protein amino acid sulfation GO:0006477 5 5 0,000 3,728E-03 0,07971239 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 6 5 0,000 3,728E-03 0,07923791 ! embryonic camera-type eye development GO:0031076 7 5 0,000 3,728E-03 0,07876904 GO:0048596|embryonic camera-type eye morphogenesis, ! opioid peptide activity GO:0001515 5 5 0,000 3,728E-03 0,0783057 ! selenocysteine incorporation GO:0001514 5 5 0,000 3,728E-03 0,07784777 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 5 5 0,000 3,728E-03 0,07739517 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 5 5 0,000 3,728E-03 0,07694779 ! elastic fiber assembly GO:0048251 5 5 0,000 3,728E-03 0,07650557 ! regulation of mitochondrial membrane permeability GO:0046902 5 5 0,000 3,728E-03 0,07606839 ! neurofilament cytoskeleton organization GO:0060052 5 5 0,000 3,728E-03 0,07563618 ! ruffle membrane GO:0032587 5 5 0,000 3,728E-03 0,07520886 ! regulation of histone modification GO:0031056 5 5 0,000 3,728E-03 0,07478634 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 3,728E-03 0,07436854 ! behavioral response to pain GO:0048266 5 5 0,000 3,728E-03 0,07395538 ! clathrin coat assembly GO:0048268 6 5 0,000 3,728E-03 0,07354679 ! Notch receptor processing GO:0007220 5 5 0,000 3,728E-03 0,07314268 ! cerebral cortex radially oriented cell migration GO:0021799 5 5 0,000 3,728E-03 0,072743 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 6 5 0,000 3,728E-03 0,07234765 ! serotonin receptor signaling pathway GO:0007210 5 5 0,000 3,728E-03 0,07195659 ! oxidoreductase activity, oxidizing metal ions GO:0016722 5 5 0,000 3,728E-03 0,07156972 ! response to lipid GO:0033993 5 5 0,000 3,728E-03 0,071187 ! cytoplasmic dynein complex GO:0005868 6 5 0,000 3,728E-03 0,07080834 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 3,728E-03 0,0704337 ! positive regulation of muscle cell differentiation GO:0051149 5 5 0,000 3,728E-03 0,07006299 ! smooth muscle cell differentiation GO:0051145 5 5 0,000 3,728E-03 0,06969617 ! exo-alpha-sialidase activity GO:0004308 5 5 0,000 3,728E-03 0,06933317 GO:0016997|alpha-sialidase activity, ! regulation of odontogenesis GO:0042481 5 5 0,000 3,728E-03 0,06897393 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 3,728E-03 0,06861839 ! formate-tetrahydrofolate ligase activity GO:0004329 5 5 0,000 3,728E-03 0,06826651 ! negative regulation of heart contraction GO:0045822 5 5 0,000 3,728E-03 0,06791821 ! ovulation from ovarian follicle GO:0001542 5 5 0,000 3,728E-03 0,06757344 ! DNA ligation during DNA repair GO:0051103 5 5 0,000 3,728E-03 0,06723216 ! 1-acylglycerophosphocholine O-acyltransferase activity GO:0047184 5 5 0,000 3,728E-03 0,06689431 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 3,728E-03 0,06655984 ! negative regulation of endocytosis GO:0045806 5 5 0,000 3,728E-03 0,0662287 ! microfibril GO:0001527 5 5 0,000 3,728E-03 0,06590083 GO:0043205|fibril, ! parathyroid gland development GO:0060017 5 5 0,000 3,728E-03 0,0655762 ! toxin metabolic process GO:0009404 5 5 0,000 3,728E-03 0,06525475 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 3,728E-03 0,06493643 ! cytokine secretion GO:0050663 5 5 0,000 3,728E-03 0,06462121 ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 5 5 0,000 3,728E-03 0,06430903 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 3,728E-03 0,06399985 ! skeletal myofibril assembly GO:0014866 5 5 0,000 3,728E-03 0,06369363 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 5 0,000 3,728E-03 0,06339033 ! epithelial cell proliferation GO:0050673 5 5 0,000 3,728E-03 0,0630899 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 5 5 0,000 3,728E-03 0,0627923 ! regulation of retroviral genome replication GO:0045091 5 5 0,000 3,728E-03 0,0624975 ! negative regulation of survival gene product expression GO:0008634 5 5 0,000 3,728E-03 0,06220546 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 3,728E-03 0,06191613 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of defense response to virus by host GO:0050691 5 5 0,000 3,728E-03 0,06162948 ! transmembrane-ephrin receptor activity GO:0005005 5 5 0,000 3,728E-03 0,06134548 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 3,728E-03 0,06106408 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 3,728E-03 0,06078524 ! glutamate catabolic process GO:0006538 6 5 0,000 3,728E-03 0,06050895 ! positive regulation of isotype switching to IgG isotypes GO:0048304 9 5 0,000 3,728E-03 0,06023515 ! microvillus organization GO:0032528 5 5 0,000 3,728E-03 0,05996382 GO:0030033|microvillus assembly, ! tyrosine catabolic process GO:0006572 5 5 0,000 3,728E-03 0,05969493 ! L-serine biosynthetic process GO:0006564 5 5 0,000 3,728E-03 0,05942843 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 3,728E-03 0,0591643 ! pericentriolar material GO:0000242 6 5 0,000 3,728E-03 0,05890252 ! polyol biosynthetic process GO:0046173 5 5 0,000 3,728E-03 0,05864303 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 6 5 0,000 3,728E-03 0,05838583 ! platelet-derived growth factor alpha-receptor activity GO:0005018 5 5 0,000 3,728E-03 0,05813087 ! proton-transporting V-type ATPase, V0 domain GO:0033179 5 5 0,000 3,728E-03 0,05787812 ! fibroblast growth factor receptor activity GO:0005007 5 5 0,000 3,728E-03 0,05762757 ! protein-DNA loading ATPase activity GO:0033170 5 5 0,000 3,728E-03 0,05737917 GO:0003689|DNA clamp loader activity, ! insulin-like growth factor receptor activity GO:0005010 5 5 0,000 3,728E-03 0,05713291 ! response to tumor necrosis factor GO:0034612 6 5 0,000 3,728E-03 0,05688875 ! mRNA transcription GO:0009299 6 5 0,000 3,728E-03 0,05664667 ! response to ATP GO:0033198 5 5 0,000 3,728E-03 0,05640665 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 5 5 0,000 3,728E-03 0,05616864 ! adenosine receptor activity, G-protein coupled GO:0001609 5 5 0,000 3,728E-03 0,05593264 ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 3,728E-03 0,05569861 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 5 5 0,000 3,728E-03 0,05546654 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 3,728E-03 0,05523638 ! multivesicular body GO:0005771 5 5 0,000 3,728E-03 0,05500813 ! positive regulation of transporter activity GO:0032411 5 5 0,000 3,728E-03 0,05478176 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 5 5 0,000 3,728E-03 0,05455725 ! forebrain neuron development GO:0021884 6 5 0,000 3,728E-03 0,05433457 ! insulin-like growth factor I binding GO:0031994 5 5 0,000 3,728E-03 0,05411369 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 5 5 0,000 3,728E-03 0,05389461 ! demethylase activity GO:0032451 5 5 0,000 3,728E-03 0,05367729 ! peptidyl-histidine phosphorylation GO:0018106 5 5 0,000 3,728E-03 0,05346172 ! epithelial cell maturation GO:0002070 5 5 0,000 3,728E-03 0,05324787 ! nitric-oxide synthase regulator activity GO:0030235 5 5 0,000 3,728E-03 0,05303573 ! regulation of immunoglobulin secretion GO:0051023 5 5 0,000 3,728E-03 0,05282527 ! zymogen granule GO:0042588 5 5 0,000 3,728E-03 0,05261648 ! guanylate cyclase regulator activity GO:0030249 5 5 0,000 3,728E-03 0,05240932 GO:0010851|cyclase regulator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 3,728E-03 0,0522038 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! cellular glucose homeostasis GO:0001678 5 5 0,000 3,728E-03 0,05199988 ! early endosome to late endosome transport GO:0045022 5 5 0,000 3,728E-03 0,05179754 ! positive regulation of translational initiation GO:0045948 5 5 0,000 3,728E-03 0,05159678 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 3,728E-03 0,05139756 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 3,728E-03 0,05119988 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! semaphorin receptor activity GO:0017154 6 5 0,000 3,728E-03 0,05100371 ! proteoglycan binding GO:0043394 9 5 0,000 3,728E-03 0,05080904 ! regulation of collagen metabolic process GO:0010712 6 5 0,000 3,728E-03 0,05061585 ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 6 5 0,000 3,728E-03 0,05042412 ! zinc ion homeostasis GO:0055069 5 5 0,000 3,728E-03 0,05023384 GO:0006882|cellular zinc ion homeostasis, ! deoxyribonucleoside metabolic process GO:0009120 6 5 0,000 3,728E-03 0,05004499 ! nucleoside monophosphate catabolic process GO:0009125 5 5 0,000 3,728E-03 0,04985756 ! activated T cell proliferation GO:0050798 6 5 0,000 3,728E-03 0,04967152 ! advanced glycation end-product receptor activity GO:0050785 5 5 0,000 3,728E-03 0,04948687 ! dynein binding GO:0045502 5 5 0,000 3,728E-03 0,04930359 ! regulation of dendrite development GO:0050773 5 5 0,000 3,728E-03 0,04912165 ! cardiac muscle cell development GO:0055013 5 5 0,000 3,728E-03 0,04894106 ! anterograde axon cargo transport GO:0008089 5 5 0,000 3,728E-03 0,04876179 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 3,728E-03 0,04858383 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 3,728E-03 0,04840716 GO:0003923|GPI-anchor transamidase activity, ! lymphoid progenitor cell differentiation GO:0002320 5 5 0,000 3,728E-03 0,04823177 ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 3,728E-03 0,04805765 ! MutLalpha complex binding GO:0032405 6 5 0,000 3,728E-03 0,04788478 ! sphingomyelin catabolic process GO:0006685 6 5 0,000 3,728E-03 0,04771315 ! high-density lipoprotein binding GO:0008035 5 5 0,000 3,728E-03 0,04754274 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 3,728E-03 0,04737355 ! positive regulation of B cell differentiation GO:0045579 5 5 0,000 3,728E-03 0,04720556 ! regulation of acetylcholine secretion GO:0014056 5 5 0,000 3,728E-03 0,04703876 ! centromeric DNA binding GO:0019237 5 5 0,000 3,728E-03 0,04687313 ! cyclohydrolase activity GO:0019238 5 5 0,000 3,728E-03 0,04670866 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 3,728E-03 0,04654534 ! positive T cell selection GO:0043368 9 5 0,000 3,728E-03 0,04638317 ! neural tube patterning GO:0021532 5 5 0,000 3,728E-03 0,04622211 ! amylase activity GO:0016160 5 5 0,000 3,728E-03 0,04606217 ! metaphase plate congression GO:0051310 5 5 0,000 3,728E-03 0,04590334 ! regulation of sterol transport GO:0032371 5 5 0,000 3,728E-03 0,0457456 GO:0032374|regulation of cholesterol transport, ! sympathetic nervous system development GO:0048485 5 5 0,000 3,728E-03 0,04558893 ! oxygen homeostasis GO:0032364 5 5 0,000 3,728E-03 0,04543334 ! skeletal muscle regeneration GO:0043403 5 5 0,000 3,728E-03 0,0452788 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 5 5 0,000 3,728E-03 0,04512532 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 5 5 0,000 3,728E-03 0,04497287 ! SAP kinase activity GO:0016909 5 5 0,000 3,728E-03 0,04482144 ! positive regulation of pseudopodium assembly GO:0031274 5 5 0,000 3,728E-03 0,04467104 GO:0031272|regulation of pseudopodium assembly, ! phosphatidylserine binding GO:0001786 5 5 0,000 3,728E-03 0,04452163 ! alpha-mannosidase activity GO:0004559 6 5 0,000 3,728E-03 0,04437323 ! alpha-glucosidase activity GO:0004558 6 5 0,000 3,728E-03 0,04422581 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 3,728E-03 0,04407937 ! myeloid dendritic cell activation GO:0001773 5 5 0,000 3,728E-03 0,04393389 GO:0043011|myeloid dendritic cell differentiation, ! anaphase GO:0051322 5 5 0,000 3,728E-03 0,04378937 GO:0000090|mitotic anaphase, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 3,728E-03 0,0436458 ! ribonuclease H activity GO:0004523 5 5 0,000 3,728E-03 0,04350316 ! CARD domain binding GO:0050700 5 5 0,000 3,728E-03 0,04336146 ! regulation of muscle cell apoptosis GO:0010660 5 5 0,000 3,728E-03 0,04322068 ! AP-2 adaptor complex GO:0030122 5 5 0,000 3,728E-03 0,0430808 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 5 5 0,000 3,728E-03 0,04294183 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 3,728E-03 0,04280376 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 3,728E-03 0,04266657 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 3,728E-03 0,04253025 ! negative regulation of macrophage differentiation GO:0045650 5 5 0,000 3,728E-03 0,0423948 ! negative regulation of osteoclast differentiation GO:0045671 5 5 0,000 3,728E-03 0,04226022 ! ceramidase activity GO:0017040 5 5 0,000 3,728E-03 0,04212648 ! negative regulation of osteoblast differentiation GO:0045668 6 5 0,000 3,728E-03 0,04199359 ! GTP-Rho binding GO:0017049 5 5 0,000 3,728E-03 0,04186154 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 3,728E-03 0,04173031 ! chondroitin sulfotransferase activity GO:0034481 5 5 0,000 3,728E-03 0,0415999 ! positive regulation of T-helper 2 cell differentiation GO:0045630 5 5 0,000 3,728E-03 0,04147031 ! alcohol transmembrane transporter activity GO:0015665 5 5 0,000 3,728E-03 0,04134152 GO:0015166|polyol transmembrane transporter activity, ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 3,728E-03 0,04121352 ! TAP complex GO:0042825 5 5 0,000 3,728E-03 0,04108632 ! bHLH transcription factor binding GO:0043425 5 5 0,000 3,728E-03 0,0409599 ! actinin binding GO:0042805 6 5 0,000 3,728E-03 0,04083426 ! secretory granule organization GO:0033363 5 5 0,000 3,728E-03 0,04070938 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 5 5 0,000 3,728E-03 0,04058527 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 3,728E-03 0,04046191 ! striatum development GO:0021756 5 5 0,000 3,728E-03 0,0403393 ! photoreceptor inner segment GO:0001917 5 5 0,000 3,728E-03 0,04021743 ! regulation of T cell mediated cytotoxicity GO:0001914 9 5 0,000 3,728E-03 0,04009629 ! aldehyde-lyase activity GO:0016832 5 5 0,000 3,728E-03 0,03997588 ! regulation of mitochondrial depolarization GO:0051900 5 5 0,000 3,728E-03 0,03985619 ! T cell activation during immune response GO:0002286 5 5 0,000 3,728E-03 0,03973722 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 3,728E-03 0,03961895 ! 1-aminocyclopropane-1-carboxylate synthase activity GO:0016847 5 5 0,000 3,728E-03 0,03950139 ! dystroglycan complex GO:0016011 6 5 0,000 3,728E-03 0,03938452 ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 5 5 0,000 3,728E-03 0,03926834 ! neural plate development GO:0001840 5 5 0,000 3,728E-03 0,03915285 ! toll-like receptor signaling pathway GO:0002224 5 5 0,000 3,728E-03 0,03903803 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 3,728E-03 0,03892388 ! phosphopantetheine binding GO:0031177 5 5 0,000 3,728E-03 0,0388104 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 3,728E-03 0,03869758 ! negative regulation of actin filament bundle formation GO:0032232 8 5 0,000 3,728E-03 0,03858542 GO:0051497|negative regulation of stress fiber formation, ! organ or tissue specific immune response GO:0002251 5 5 0,000 3,728E-03 0,0384739 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 3,728E-03 0,03836302 ! diacylglycerol metabolic process GO:0046339 5 5 0,000 3,728E-03 0,03825278 ! cytoplasmic microtubule organization GO:0031122 5 5 0,000 3,728E-03 0,03814318 ! retina homeostasis GO:0001895 5 5 0,000 3,728E-03 0,0380342 ! release of sequestered calcium ion into cytosol GO:0051209 10 5 0,000 3,728E-03 0,03792584 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 5 5 0,000 3,728E-03 0,03781809 ! regulation of growth hormone secretion GO:0060123 6 5 0,000 3,728E-03 0,03771096 ! collagen type IV GO:0005587 5 5 0,000 3,728E-03 0,03760443 ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 3,728E-03 0,0374985 ! testosterone 17-beta-dehydrogenase (NADP+) activity GO:0047045 5 5 0,000 3,728E-03 0,03739317 ! retrograde protein transport, ER to cytosol GO:0030970 5 5 0,000 3,728E-03 0,03728843 ! spindle assembly GO:0051225 5 5 0,000 3,728E-03 0,03718427 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 3,728E-03 0,03708069 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 5 5 0,000 3,728E-03 0,03697769 GO:0022011|myelination in the peripheral nervous system, ! drug metabolic process GO:0017144 5 5 0,000 3,728E-03 0,03687526 ! protein amino acid prenylation GO:0018346 5 5 0,000 3,728E-03 0,03677339 ! stem cell division GO:0017145 5 5 0,000 3,728E-03 0,03667209 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 3,728E-03 0,03657134 ! phospholipid scrambling GO:0017121 5 5 0,000 3,728E-03 0,03647115 GO:0017128|phospholipid scramblase activity, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 5 5 0,000 3,728E-03 0,0363715 ! regulation of humoral immune response GO:0002920 9 5 0,000 3,728E-03 0,03627239 ! H3/H4 histone acetyltransferase activity GO:0004406 5 5 0,000 3,728E-03 0,03617383 ! regulation of interferon-alpha biosynthetic process GO:0045354 6 5 0,000 3,728E-03 0,0360758 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 3,728E-03 0,03597829 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of cAMP biosynthetic process GO:0030819 5 5 0,000 3,728E-03 0,03588132 GO:0030816|positive regulation of cAMP metabolic process, ! phagocytic vesicle GO:0045335 5 5 0,000 3,728E-03 0,03578486 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 3,728E-03 0,03568892 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 3,728E-03 0,0355935 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 3,728E-03 0,03549858 ! polyol transport GO:0015791 6 5 0,000 3,728E-03 0,03540417 ! cell adhesion mediated by integrin GO:0033627 6 5 0,000 3,728E-03 0,03531026 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 3,728E-03 0,03521685 ! glycerol-3-phosphate metabolic process GO:0006072 5 5 0,000 3,728E-03 0,03512393 ! platelet activating factor metabolic process GO:0046469 5 5 0,000 3,728E-03 0,0350315 ! cobalt ion transport GO:0006824 5 5 0,000 3,728E-03 0,03493955 ! response to zinc ion GO:0010043 5 5 0,000 3,728E-03 0,03484809 ! poly(U) RNA binding GO:0008266 5 5 0,000 3,728E-03 0,0347571 ! negative regulation of cell-cell adhesion GO:0022408 5 5 0,000 3,728E-03 0,03466658 ! adaptation of signaling pathway GO:0022401 5 5 0,000 3,728E-03 0,03457654 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! glucocorticoid receptor signaling pathway GO:0042921 5 5 0,000 3,728E-03 0,03448696 GO:0031958|corticosteroid receptor signaling pathway, ! regulation of gluconeogenesis GO:0006111 5 5 0,000 3,728E-03 0,03439785 ! sensory perception of bitter taste GO:0050913 5 5 0,000 3,728E-03 0,0343092 ! regulation of dopamine uptake GO:0051584 5 5 0,000 3,728E-03 0,034221 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! opsonization GO:0008228 5 5 0,000 3,728E-03 0,03413325 ! protein maturation by protein folding GO:0022417 5 5 0,000 3,728E-03 0,03404596 ! neuron remodeling GO:0016322 6 5 0,000 3,728E-03 0,0339591 ! neurexin binding GO:0042043 5 5 0,000 3,728E-03 0,03387269 ! sensory perception of temperature stimulus GO:0050951 5 5 0,000 3,728E-03 0,03378672 ! regulation of potassium ion transport GO:0043266 5 5 0,000 3,728E-03 0,03370119 ! low-density lipoprotein particle GO:0034362 5 5 0,000 3,728E-03 0,03361608 ! chemoattractant activity GO:0042056 5 5 0,000 3,728E-03 0,03353141 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 6 5 0,000 3,728E-03 0,03344716 ! lipoic acid binding GO:0031405 5 5 0,000 3,728E-03 0,03336333 ! lithium ion binding GO:0031403 6 5 0,000 3,728E-03 0,03327992 ! lipoprotein particle clearance GO:0034381 5 5 0,000 3,728E-03 0,03319693 ! grooming behavior GO:0007625 5 5 0,000 3,728E-03 0,03311435 ! sequestering of actin monomers GO:0042989 5 5 0,000 3,728E-03 0,03303218 ! cobalamin binding GO:0031419 5 5 0,000 3,728E-03 0,03295042 ! retinoic acid binding GO:0001972 5 5 0,000 3,728E-03 0,03286906 ! response to axon injury GO:0048678 5 5 0,000 3,728E-03 0,0327881 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 3,728E-03 0,03270754 ! regulation of activin receptor signaling pathway GO:0032925 5 5 0,000 3,728E-03 0,03262737 ! positive regulation of neurotransmitter secretion GO:0001956 5 5 0,000 3,728E-03 0,0325476 ! mitochondrial genome maintenance GO:0000002 5 5 0,000 3,728E-03 0,03246822 ! protein-lysine 6-oxidase activity GO:0004720 6 5 0,000 3,728E-03 0,03238922 ! female pronucleus GO:0001939 5 5 0,000 3,728E-03 0,0323106 ! F-actin capping protein complex GO:0008290 5 5 0,000 3,728E-03 0,03223237 ! DNA topoisomerase activity GO:0003916 5 5 0,000 3,728E-03 0,03215451 ! poly(ADP-ribose) glycohydrolase activity GO:0004649 6 5 0,000 3,728E-03 0,03207703 ! spinal cord dorsal/ventral patterning GO:0021513 5 5 0,000 3,728E-03 0,03199992 ! dorsal spinal cord development GO:0021516 5 5 0,000 3,728E-03 0,03192319 ! ceramide catabolic process GO:0046514 5 5 0,000 3,728E-03 0,03184681 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 3,728E-03 0,03177081 ! neutrophil mediated immunity GO:0002446 5 5 0,000 3,728E-03 0,03169516 ! regulation of oligodendrocyte differentiation GO:0048713 5 5 0,000 3,728E-03 0,03161988 ! Rap GTPase activator activity GO:0046582 5 5 0,000 3,728E-03 0,03154495 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 6 5 0,000 3,728E-03 0,03147037 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 5 5 0,000 3,728E-03 0,03139615 ! positive regulation of filopodium assembly GO:0051491 5 5 0,000 3,728E-03 0,03132228 GO:0051489|regulation of filopodium assembly, ! heart trabecula formation GO:0060347 5 5 0,000 3,728E-03 0,03124875 GO:0060343|trabecula formation, ! amine oxidase activity GO:0008131 6 5 0,000 3,728E-03 0,03117557 ! neutrophil activation GO:0042119 5 5 0,000 3,728E-03 0,03110273 ! regulation of response to food GO:0032095 5 5 0,000 3,728E-03 0,03103023 ! response to food GO:0032094 5 5 0,000 3,728E-03 0,03095807 ! hedgehog receptor activity GO:0008158 5 5 0,000 3,728E-03 0,03088624 ! protein phosphatase 1 binding GO:0008157 5 5 0,000 3,728E-03 0,03081474 ! lipoprotein catabolic process GO:0042159 5 5 0,000 3,728E-03 0,03074358 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 3,728E-03 0,03067274 ! organ growth GO:0035265 7 5 0,000 3,728E-03 0,03060223 ! positive regulation of multicellular organismal metabolic process GO:0044253 6 5 0,000 3,728E-03 0,03053204 ! small-subunit processome GO:0032040 5 5 0,000 3,728E-03 0,03046217 ! UDP-glucosyltransferase activity GO:0035251 5 5 0,000 3,728E-03 0,03039262 ! myosin heavy chain binding GO:0032036 5 5 0,000 3,728E-03 0,03032339 ! nucleoside salvage GO:0043174 7 5 0,000 3,728E-03 0,03025447 GO:0006166|purine ribonucleoside salvage, ! nucleobase transport GO:0015851 5 5 0,000 3,728E-03 0,03018587 ! GPI anchor binding GO:0034235 6 5 0,000 3,728E-03 0,03011758 ! thrombin receptor activity GO:0015057 5 5 0,000 3,728E-03 0,03004959 ! nucleotide-excision repair complex GO:0000109 6 5 0,000 3,728E-03 0,02998191 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 5 5 0,000 3,728E-03 0,02991454 ! dendritic shaft GO:0043198 5 5 0,000 3,728E-03 0,02984746 ! terminal button GO:0043195 8 5 0,000 3,728E-03 0,02978069 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 3,728E-03 0,02971422 GO:0016274|protein-arginine N-methyltransferase activity, ! ferrous iron binding GO:0008198 6 5 0,000 3,728E-03 0,02964804 ! eukaryotic initiation factor 4E binding GO:0008190 5 5 0,000 3,728E-03 0,02958215 ! G2/M transition checkpoint GO:0031576 5 5 0,000 3,728E-03 0,02951656 GO:0031572|G2/M transition DNA damage checkpoint, ! negative regulation of peptide secretion GO:0002792 6 5 0,000 3,728E-03 0,02945126 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 5 5 0,000 3,728E-03 0,02938624 ! response to UV-C GO:0010225 5 5 0,000 3,728E-03 0,02932152 ! carbonyl reductase (NADPH) activity GO:0004090 5 5 0,000 3,728E-03 0,02925707 ! regulation of alpha-beta T cell proliferation GO:0046640 9 5 0,000 3,728E-03 0,02919291 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! positive regulation of organ growth GO:0046622 5 5 0,000 3,728E-03 0,02912903 ! 1-alkyl-2-acetylglycerophosphocholine esterase activity GO:0003847 5 5 0,000 3,728E-03 0,02906543 ! IgE binding GO:0019863 5 5 0,000 3,728E-03 0,02900211 ! 3-beta-hydroxy-delta5-steroid dehydrogenase activity GO:0003854 5 5 0,000 3,728E-03 0,02893906 ! monoamine transmembrane transporter activity GO:0008504 5 5 0,000 3,728E-03 0,02887629 ! response to cadmium ion GO:0046686 5 5 0,000 3,728E-03 0,02881378 ! regulation of interleukin-4 production GO:0032673 5 5 0,000 3,728E-03 0,02875155 ! hair follicle maturation GO:0048820 5 5 0,000 3,728E-03 0,02868959 ! regulation of interleukin-10 production GO:0032653 5 5 0,000 3,728E-03 0,02862789 ! ribosomal large subunit biogenesis GO:0042273 5 5 0,000 3,728E-03 0,02856646 ! base conversion or substitution editing GO:0016553 5 5 0,000 3,728E-03 0,02850529 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 3,728E-03 0,02844438 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 3,728E-03 0,02838373 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 3,728E-03 0,02832334 GO:0005218|intracellular ligand-gated calcium channel activity, ! general transcriptional repressor activity GO:0016565 5 5 0,000 3,728E-03 0,0282632 ! peroxisome fission GO:0016559 5 5 0,000 3,728E-03 0,02820332 ! alpha-tubulin binding GO:0043014 5 5 0,000 3,728E-03 0,0281437 ! mitotic recombination GO:0006312 5 5 0,000 3,728E-03 0,02808432 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 3,728E-03 0,0280252 ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 3,728E-03 0,02796632 ! positive regulation of chemokine production GO:0032722 5 5 0,000 3,728E-03 0,02790769 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 3,728E-03 0,02784931 ! muscle cell proliferation GO:0033002 5 5 0,000 3,728E-03 0,02779117 ! membrane to membrane docking GO:0022614 5 5 0,000 3,728E-03 0,02773327 ! translation activator activity GO:0008494 5 5 0,000 3,728E-03 0,02767561 ! N-formyl peptide receptor activity GO:0004982 5 5 0,000 3,728E-03 0,02761819 ! coenzyme A biosynthetic process GO:0015937 6 5 0,000 3,728E-03 0,02756101 ! histamine receptor activity GO:0004969 5 5 0,000 3,728E-03 0,02750407 ! dopamine receptor activity GO:0004952 5 5 0,000 3,728E-03 0,02744736 ! galactosidase activity GO:0015925 5 5 0,000 3,728E-03 0,02739088 ! prostaglandin E receptor activity GO:0004957 6 5 0,000 3,728E-03 0,02733464 ! cellular response to nutrient GO:0031670 5 5 0,000 3,728E-03 0,02727862 ! basic amino acid transmembrane transporter activity GO:0015174 5 5 0,000 3,728E-03 0,02722284 ! ATP-gated cation channel activity GO:0004931 7 5 0,000 3,728E-03 0,02716728 ! cytochrome-b5 reductase activity GO:0004128 5 5 0,000 3,728E-03 0,02711195 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 3,728E-03 0,02705685 ! glycine transmembrane transporter activity GO:0015187 5 5 0,000 3,728E-03 0,02700196 ! tyrosine phosphorylation of STAT protein GO:0007260 6 5 0,000 3,728E-03 0,0269473 ! tricarboxylic acid cycle enzyme complex GO:0045239 5 5 0,000 3,728E-03 0,02689287 ! RNA polymerase I transcription factor activity GO:0003701 5 5 0,000 3,728E-03 0,02683865 ! progesterone metabolic process GO:0042448 5 5 0,000 3,728E-03 0,02678464 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 5 5 0,000 3,728E-03 0,02673086 ! disaccharide metabolic process GO:0005984 5 5 0,000 3,728E-03 0,02667729 ! 5'-3' exonuclease activity GO:0008409 5 5 0,000 3,728E-03 0,02662394 ! type II transforming growth factor beta receptor binding GO:0005114 5 5 0,000 3,728E-03 0,0265708 ! histone acetyltransferase binding GO:0035035 5 5 0,000 3,728E-03 0,02651787 ! endosome to lysosome transport GO:0008333 5 5 0,000 3,728E-03 0,02646515 ! glial cell migration GO:0008347 5 5 0,000 3,728E-03 0,02641264 ! S-acyltransferase activity GO:0016417 5 5 0,000 3,728E-03 0,02636033 ! phosphoinositide 3-kinase regulator activity GO:0035014 5 5 0,000 3,728E-03 0,02630824 ! phosphatidylinositol-4-phosphate 3-kinase activity GO:0035005 5 5 0,000 3,728E-03 0,02625635 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 3,728E-03 0,02620466 ! nucleobase transmembrane transporter activity GO:0015205 5 5 0,000 3,728E-03 0,02615318 ! asparaginase activity GO:0004067 5 5 0,000 3,728E-03 0,0261019 ! insemination GO:0007320 5 5 0,000 3,728E-03 0,02605082 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 3,728E-03 0,02599994 ! negative regulation of smooth muscle contraction GO:0045986 6 5 0,000 3,728E-03 0,02594926 ! aminoacylase activity GO:0004046 5 5 0,000 3,728E-03 0,02589877 ! receptor biosynthetic process GO:0032800 5 5 0,000 3,728E-03 0,02584848 ! penetration of zona pellucida GO:0007341 5 5 0,000 3,728E-03 0,02579839 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 6 5 0,000 3,728E-03 0,02574849 ! aldehyde reductase activity GO:0004032 5 5 0,000 3,728E-03 0,02569878 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 5 0,000 3,728E-03 0,02564926 ! unconventional myosin complex GO:0016461 5 5 0,000 3,728E-03 0,02559994 ! carnitine metabolic process GO:0009437 5 5 0,000 3,728E-03 0,0255508 GO:0006577|betaine metabolic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 6 6 0,000 4,472E-03 0,03059184 ! regulation of helicase activity GO:0051095 6 6 0,000 4,472E-03 0,03053335 ! testosterone 17-beta-dehydrogenase activity GO:0050327 6 6 0,000 4,472E-03 0,03047508 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 6 6 0,000 4,472E-03 0,03041703 ! tumor necrosis factor-mediated signaling pathway GO:0033209 6 6 0,000 4,472E-03 0,03035921 ! negative regulation of small GTPase mediated signal transduction GO:0051058 7 6 0,000 4,472E-03 0,0303016 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 7 6 0,000 4,472E-03 0,03024421 ! regulation of hormone biosynthetic process GO:0046885 6 6 0,000 4,472E-03 0,03018704 ! ephrin receptor binding GO:0046875 7 6 0,000 4,472E-03 0,03013008 ! biotin binding GO:0009374 7 6 0,000 4,472E-03 0,03007334 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 4,472E-03 0,03001681 ! insulin receptor substrate binding GO:0043560 7 6 0,000 4,472E-03 0,02996049 ! drug:hydrogen antiporter activity GO:0015307 6 6 0,000 4,472E-03 0,02990439 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 4,472E-03 0,02984849 ! carbohydrate phosphorylation GO:0046835 6 6 0,000 4,472E-03 0,0297928 ! regulation of respiratory gaseous exchange GO:0043576 6 6 0,000 4,472E-03 0,02973732 ! neuron adhesion GO:0007158 6 6 0,000 4,472E-03 0,02968205 ! establishment of tissue polarity GO:0007164 7 6 0,000 4,472E-03 0,02962698 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 6 6 0,000 4,472E-03 0,02957212 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 4,472E-03 0,02951745 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 6 0,000 4,472E-03 0,02946299 ! regulation of cardiac muscle cell proliferation GO:0060043 6 6 0,000 4,472E-03 0,02940873 ! positive regulation of receptor-mediated endocytosis GO:0048260 6 6 0,000 4,472E-03 0,02935467 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 6 6 0,000 4,472E-03 0,02930081 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 4,472E-03 0,02924715 ! eukaryotic translation elongation factor 1 complex GO:0005853 6 6 0,000 4,472E-03 0,02919368 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 4,472E-03 0,02914041 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 6 6 0,000 4,472E-03 0,02908733 ! cytoplasmic microtubule GO:0005881 7 6 0,000 4,472E-03 0,02903444 ! Arp2/3 protein complex GO:0005885 7 6 0,000 4,472E-03 0,02898175 ! neurofilament GO:0005883 6 6 0,000 4,472E-03 0,02892924 ! glial cell fate commitment GO:0021781 6 6 0,000 4,472E-03 0,02887693 ! dynactin complex GO:0005869 6 6 0,000 4,472E-03 0,02882481 ! fibroblast growth factor receptor antagonist activity GO:0030353 6 6 0,000 4,472E-03 0,02877287 GO:0005104|fibroblast growth factor receptor binding, GO:0005152|interleukin-1 receptor antagonist activity, ! translation repressor activity GO:0030371 6 6 0,000 4,472E-03 0,02872112 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 6 6 0,000 4,472E-03 0,02866956 ! lipopolysaccharide binding GO:0001530 6 6 0,000 4,472E-03 0,02861818 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 4,472E-03 0,02856698 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 4,472E-03 0,02851597 ! negative regulation of viral genome replication GO:0045071 6 6 0,000 4,472E-03 0,02846514 ! traversing start control point of mitotic cell cycle GO:0007089 6 6 0,000 4,472E-03 0,02841449 ! protein lipoylation GO:0009249 6 6 0,000 4,472E-03 0,02836402 ! cysteine metabolic process GO:0006534 6 6 0,000 4,472E-03 0,02831373 ! regulation of isotype switching to IgG isotypes GO:0048302 10 6 0,000 4,472E-03 0,02826361 ! histidine catabolic process GO:0006548 6 6 0,000 4,472E-03 0,02821368 GO:0009077|histidine family amino acid catabolic process, ! centromeric heterochromatin GO:0005721 6 6 0,000 4,472E-03 0,02816392 ! mitochondrial respiratory chain complex assembly GO:0033108 6 6 0,000 4,472E-03 0,02811434 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 6 6 0,000 4,472E-03 0,02806493 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 6 6 0,000 4,472E-03 0,02801569 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 6 6 0,000 4,472E-03 0,02796662 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 6 0,000 4,472E-03 0,02791773 ! microtubule nucleation GO:0007020 6 6 0,000 4,472E-03 0,02786901 ! proline biosynthetic process GO:0006561 7 6 0,000 4,472E-03 0,02782046 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 4,472E-03 0,02777207 ! transforming growth factor beta receptor activity, type I GO:0005025 6 6 0,000 4,472E-03 0,02772386 ! phasic smooth muscle contraction GO:0014821 6 6 0,000 4,472E-03 0,02767581 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 4,472E-03 0,02762793 ! peptidoglycan metabolic process GO:0000270 6 6 0,000 4,472E-03 0,02758021 GO:0009253|peptidoglycan catabolic process, ! cerebral cortex neuron differentiation GO:0021895 6 6 0,000 4,472E-03 0,02753266 ! paraxial mesoderm development GO:0048339 6 6 0,000 4,472E-03 0,02748527 ! melanosome organization GO:0032438 6 6 0,000 4,472E-03 0,02743805 ! mitochondrial outer membrane translocase complex GO:0005742 6 6 0,000 4,472E-03 0,02739098 ! flotillin complex GO:0016600 6 6 0,000 4,472E-03 0,02734408 ! positive regulation of neuroblast proliferation GO:0002052 6 6 0,000 4,472E-03 0,02729734 ! positive regulation of vasoconstriction GO:0045907 6 6 0,000 4,472E-03 0,02725075 ! negative regulation of DNA recombination GO:0045910 6 6 0,000 4,472E-03 0,02720433 ! positive regulation of exocytosis GO:0045921 7 6 0,000 4,472E-03 0,02715807 ! protein tyrosine kinase activator activity GO:0030296 6 6 0,000 4,472E-03 0,02711196 ! positive regulation of fatty acid metabolic process GO:0045923 6 6 0,000 4,472E-03 0,027066 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 4,472E-03 0,02702021 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of mitotic cell cycle GO:0045931 6 6 0,000 4,472E-03 0,02697456 ! nonhomologous end joining complex GO:0070419 6 6 0,000 4,472E-03 0,02692908 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! DNA damage response, signal transduction resulting in transcription GO:0042772 9 6 0,000 4,472E-03 0,02688374 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! vinculin binding GO:0017166 6 6 0,000 4,472E-03 0,02683856 ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 4,472E-03 0,02679353 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 4,472E-03 0,02674865 ! sodium ion homeostasis GO:0055078 6 6 0,000 4,472E-03 0,02670392 ! protein heterooligomerization GO:0051291 6 6 0,000 4,472E-03 0,02665934 ! negative regulation of gliogenesis GO:0014014 6 6 0,000 4,472E-03 0,0266149 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 8 6 0,000 4,472E-03 0,02657062 ! translation termination factor activity GO:0008079 6 6 0,000 4,472E-03 0,02652648 GO:0003747|translation release factor activity, ! centrosome duplication GO:0051298 6 6 0,000 4,472E-03 0,02648249 ! astrocyte development GO:0014002 6 6 0,000 4,472E-03 0,02643865 ! protein targeting to lysosome GO:0006622 6 6 0,000 4,472E-03 0,02639495 ! purine base biosynthetic process GO:0009113 7 6 0,000 4,472E-03 0,02635139 ! fibrinolysis GO:0042730 7 6 0,000 4,472E-03 0,02630798 ! peptidyl-asparagine modification GO:0018196 6 6 0,000 4,472E-03 0,02626471 GO:0018279|protein amino acid N-linked glycosylation via asparagine, GO:0004579|dolichyl-diphosphooligosaccharide-protein glycotransferase activity, ! eating behavior GO:0042755 6 6 0,000 4,472E-03 0,02622158 ! B cell lineage commitment GO:0002326 6 6 0,000 4,472E-03 0,02617859 ! thiamin and derivative metabolic process GO:0042723 6 6 0,000 4,472E-03 0,02613575 ! response to exogenous dsRNA GO:0043330 6 6 0,000 4,472E-03 0,02609304 ! enucleate erythrocyte differentiation GO:0043353 6 6 0,000 4,472E-03 0,02605048 ! melanosome transport GO:0032402 6 6 0,000 4,472E-03 0,02600805 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 6 6 0,000 4,472E-03 0,02596576 GO:0014066|regulation of phosphoinositide 3-kinase cascade, ! mast cell activation GO:0045576 6 6 0,000 4,472E-03 0,02592361 ! regulation of dopamine secretion GO:0014059 6 6 0,000 4,472E-03 0,02588159 ! regulation of protein kinase B signaling cascade GO:0051896 6 6 0,000 4,472E-03 0,02583971 ! negative regulation of focal adhesion formation GO:0051895 8 6 0,000 4,472E-03 0,02579797 ! nucleoside catabolic process GO:0009164 7 6 0,000 4,472E-03 0,02575636 ! transcription initiation factor activity GO:0016986 6 6 0,000 4,472E-03 0,02571488 ! negative regulation of T cell differentiation GO:0045581 6 6 0,000 4,472E-03 0,02567354 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 4,472E-03 0,02563233 ! Schwann cell development GO:0014044 6 6 0,000 4,472E-03 0,02559125 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 6 0,000 4,472E-03 0,02555031 ! G-protein coupled photoreceptor activity GO:0008020 6 6 0,000 4,472E-03 0,02550949 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 4,472E-03 0,02546881 ! regulation of chondrocyte differentiation GO:0032330 6 6 0,000 4,472E-03 0,02542825 ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 4,472E-03 0,02538783 ! superoxide-generating NADPH oxidase activity GO:0016175 6 6 0,000 4,472E-03 0,02534753 ! nuclear envelope lumen GO:0005641 6 6 0,000 4,472E-03 0,02530736 ! RNA polymerase II transcription elongation factor activity GO:0016944 7 6 0,000 4,472E-03 0,02526731 ! regulation of meiosis GO:0040020 6 6 0,000 4,472E-03 0,0252274 GO:0051445|regulation of meiotic cell cycle, ! establishment of nucleus localization GO:0040023 8 6 0,000 4,472E-03 0,02518761 ! lipoxygenase activity GO:0016165 6 6 0,000 4,472E-03 0,02514794 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 4,472E-03 0,0251084 ! alpha DNA polymerase:primase complex GO:0005658 7 6 0,000 4,472E-03 0,02506898 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 4,472E-03 0,02502969 ! DNA replication factor C complex GO:0005663 6 6 0,000 4,472E-03 0,02499052 ! nuclear origin of replication recognition complex GO:0005664 6 6 0,000 4,472E-03 0,02495147 GO:0000808|origin recognition complex, ! DNA replication factor A complex GO:0005662 6 6 0,000 4,472E-03 0,02491255 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 4,472E-03 0,02487374 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 4,472E-03 0,02483506 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 4,472E-03 0,02479649 ! chromatin silencing complex GO:0005677 6 6 0,000 4,472E-03 0,02475805 GO:0034979|NAD-dependent protein deacetylase activity, GO:0017136|NAD-dependent histone deacetylase activity, ! U12-type spliceosomal complex GO:0005689 7 6 0,000 4,472E-03 0,02471973 ! B cell homeostasis GO:0001782 7 6 0,000 4,472E-03 0,02468152 ! regulation of respiratory burst GO:0060263 6 6 0,000 4,472E-03 0,02464343 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 10 6 0,000 4,472E-03 0,02460546 GO:0002820|negative regulation of adaptive immune response, ! immunological synapse GO:0001772 6 6 0,000 4,472E-03 0,0245676 ! MutLalpha complex GO:0032389 6 6 0,000 4,472E-03 0,02452987 ! leading edge membrane GO:0031256 6 6 0,000 4,472E-03 0,02449224 ! bis(5'-adenosyl)-triphosphatase activity GO:0047710 6 6 0,000 4,472E-03 0,02445474 ! peptidyl-histidine modification GO:0018202 6 6 0,000 4,472E-03 0,02441734 ! exodeoxyribonuclease activity GO:0004529 6 6 0,000 4,472E-03 0,02438006 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! COPII vesicle coat GO:0030127 6 6 0,000 4,472E-03 0,0243429 GO:0012507|ER to Golgi transport vesicle membrane, ! peptidyl-threonine modification GO:0018210 6 6 0,000 4,472E-03 0,02430585 ! diuresis GO:0030146 6 6 0,000 4,472E-03 0,02426891 GO:0030147|natriuresis, ! definitive hemopoiesis GO:0060216 6 6 0,000 4,472E-03 0,02423208 ! glutathione biosynthetic process GO:0006750 6 6 0,000 4,472E-03 0,02419537 ! HLA-B specific inhibitory MHC class I receptor activity GO:0030109 6 6 0,000 4,472E-03 0,02415876 ! BBSome GO:0034464 6 6 0,000 4,472E-03 0,02412227 ! regulation of keratinocyte differentiation GO:0045616 6 6 0,000 4,472E-03 0,02408589 ! glycerophosphodiester phosphodiesterase activity GO:0008889 6 6 0,000 4,472E-03 0,02404961 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 4,472E-03 0,02401345 ! sodium channel regulator activity GO:0017080 6 6 0,000 4,472E-03 0,02397739 ! glycolipid catabolic process GO:0019377 6 6 0,000 4,472E-03 0,02394144 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 6 6 0,000 4,472E-03 0,0239056 ! nicotinamide nucleotide biosynthetic process GO:0019359 6 6 0,000 4,472E-03 0,02386987 ! porphyrin catabolic process GO:0006787 8 6 0,000 4,472E-03 0,02383424 GO:0033015|tetrapyrrole catabolic process, ! removal of superoxide radicals GO:0019430 6 6 0,000 4,472E-03 0,02379872 ! positive regulation of glucose import GO:0046326 7 6 0,000 4,472E-03 0,02376331 GO:0010828|positive regulation of glucose transport, ! triglyceride catabolic process GO:0019433 6 6 0,000 4,472E-03 0,023728 ! myeloid cell homeostasis GO:0002262 6 6 0,000 4,472E-03 0,02369279 ! lamin binding GO:0005521 6 6 0,000 4,472E-03 0,02365769 ! ectodermal gut morphogenesis GO:0048567 6 6 0,000 4,472E-03 0,0236227 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 6 6 0,000 4,472E-03 0,0235878 ! pattern recognition receptor signaling pathway GO:0002221 6 6 0,000 4,472E-03 0,02355301 ! negative regulation of calcium ion transport GO:0051926 6 6 0,000 4,472E-03 0,02351832 ! peroxiredoxin activity GO:0051920 6 6 0,000 4,472E-03 0,02348374 ! complement binding GO:0001848 8 6 0,000 4,472E-03 0,02344925 ! catecholamine transport GO:0051937 6 6 0,000 4,472E-03 0,02341487 ! regulation of sensory perception GO:0051931 6 6 0,000 4,472E-03 0,02338059 GO:0051930|regulation of sensory perception of pain, ! muscle adaptation GO:0043500 6 6 0,000 4,472E-03 0,02334641 ! hemopoietic progenitor cell differentiation GO:0002244 6 6 0,000 4,472E-03 0,02331232 ! dipeptidase activity GO:0016805 6 6 0,000 4,472E-03 0,02327834 ! ether hydrolase activity GO:0016803 6 6 0,000 4,472E-03 0,02324446 ! FACIT collagen GO:0005593 6 6 0,000 4,472E-03 0,02321067 ! actin filament polymerization GO:0030041 8 6 0,000 4,472E-03 0,02317698 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 4,472E-03 0,02314339 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 6 6 0,000 4,472E-03 0,0231099 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 6 0,000 4,472E-03 0,02307651 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 4,472E-03 0,02304321 ! negative regulation of synaptic transmission GO:0050805 7 6 0,000 4,472E-03 0,02301 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 4,472E-03 0,0229769 ! organ regeneration GO:0031100 6 6 0,000 4,472E-03 0,02294388 ! Golgi transport complex GO:0017119 6 6 0,000 4,472E-03 0,02291096 ! sheet-forming collagen GO:0030935 6 6 0,000 4,472E-03 0,02287814 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 4,472E-03 0,02284541 ! positive regulation of coagulation GO:0050820 7 6 0,000 4,472E-03 0,02281277 ! defense response to Gram-negative bacterium GO:0050829 6 6 0,000 4,472E-03 0,02278023 ! positive regulation of MHC class II biosynthetic process GO:0045348 6 6 0,000 4,472E-03 0,02274778 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 6 6 0,000 4,472E-03 0,02271542 ! thioredoxin-disulfide reductase activity GO:0004791 6 6 0,000 4,472E-03 0,02268316 ! sphingomyelin phosphodiesterase activity GO:0004767 7 6 0,000 4,472E-03 0,02265098 ! regulation of cGMP metabolic process GO:0030823 6 6 0,000 4,472E-03 0,0226189 ! myoblast cell fate commitment GO:0048625 6 6 0,000 4,472E-03 0,02258691 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 4,472E-03 0,022555 ! DNA synthesis during DNA repair GO:0000731 7 6 0,000 4,472E-03 0,02252319 ! neutral lipid biosynthetic process GO:0046460 6 6 0,000 4,472E-03 0,02249147 GO:0046463|acylglycerol biosynthetic process, ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 6 6 0,000 4,472E-03 0,02245983 ! nuclear telomere cap complex GO:0000783 6 6 0,000 4,472E-03 0,02242829 GO:0000782|telomere cap complex, ! Golgi to endosome transport GO:0006895 6 6 0,000 4,472E-03 0,02239683 ! negative regulation of JAK-STAT cascade GO:0046426 7 6 0,000 4,472E-03 0,02236547 ! sterol carrier activity GO:0005498 6 6 0,000 4,472E-03 0,02233419 ! positive regulation of cell-cell adhesion GO:0022409 6 6 0,000 4,472E-03 0,02230299 ! succinate metabolic process GO:0006105 6 6 0,000 4,472E-03 0,02227189 ! myelin sheath GO:0043209 6 6 0,000 4,472E-03 0,02224087 ! perikaryon GO:0043204 7 6 0,000 4,472E-03 0,02220993 ! oxaloacetate metabolic process GO:0006107 7 6 0,000 4,472E-03 0,02217909 ! malate metabolic process GO:0006108 6 6 0,000 4,472E-03 0,02214833 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 6 6 0,000 4,472E-03 0,02211765 ! posttranscriptional gene silencing by RNA GO:0035194 6 6 0,000 4,472E-03 0,02208706 GO:0016441|posttranscriptional gene silencing, ! mating behavior GO:0007617 6 6 0,000 4,472E-03 0,02205655 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 4,472E-03 0,02202613 ! rhythmic behavior GO:0007622 7 6 0,000 4,472E-03 0,02199579 ! copulation GO:0007620 6 6 0,000 4,472E-03 0,02196553 ! erythrocyte maturation GO:0043249 6 6 0,000 4,472E-03 0,02193536 ! equilibrioception GO:0050957 6 6 0,000 4,472E-03 0,02190527 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 4,472E-03 0,02187526 ! G-protein coupled receptor kinase activity GO:0004703 6 6 0,000 4,472E-03 0,02184534 ! chemosensory behavior GO:0007635 6 6 0,000 4,472E-03 0,0218155 ! synaptic transmission, dopaminergic GO:0001963 7 6 0,000 4,472E-03 0,02178573 ! mechanosensory behavior GO:0007638 6 6 0,000 4,472E-03 0,02175605 ! response to interferon-gamma GO:0034341 6 6 0,000 4,472E-03 0,02172645 ! spinal cord patterning GO:0021511 6 6 0,000 4,472E-03 0,02169693 ! cGMP-mediated signaling GO:0019934 6 6 0,000 4,472E-03 0,02166749 ! protein geranylgeranyltransferase activity GO:0004661 6 6 0,000 4,472E-03 0,02163813 ! activation of MAPKKK activity GO:0000185 6 6 0,000 4,472E-03 0,02160885 ! nerve growth factor receptor signaling pathway GO:0048011 8 6 0,000 4,472E-03 0,02157965 ! glucosyltransferase activity GO:0046527 6 6 0,000 4,472E-03 0,02155053 ! sphingoid catabolic process GO:0046521 6 6 0,000 4,472E-03 0,02152149 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 4,472E-03 0,02149252 ! activin receptor activity GO:0017002 6 6 0,000 4,472E-03 0,02146363 ! ovulation GO:0030728 6 6 0,000 4,472E-03 0,02143482 ! dopamine binding GO:0035240 7 6 0,000 4,472E-03 0,02140609 ! hyperosmotic response GO:0006972 6 6 0,000 4,472E-03 0,02137743 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 6 6 0,000 4,472E-03 0,02134885 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 6 0,000 4,472E-03 0,02132035 ! nuclear localization sequence binding GO:0008139 6 6 0,000 4,472E-03 0,02129192 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 4,472E-03 0,02126357 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 4,472E-03 0,0212353 ! copper ion transmembrane transporter activity GO:0005375 6 6 0,000 4,472E-03 0,02120709 ! poly(A) RNA binding GO:0008143 6 6 0,000 4,472E-03 0,02117897 ! positive transcription elongation factor activity GO:0008159 6 6 0,000 4,472E-03 0,02115092 ! regulation of glycogen metabolic process GO:0070873 7 6 0,000 4,472E-03 0,02112294 GO:0032881|regulation of polysaccharide metabolic process, ! maintenance of protein location in nucleus GO:0051457 6 6 0,000 4,472E-03 0,02109504 ! intracellular pH reduction GO:0051452 6 6 0,000 4,472E-03 0,02106721 GO:0045851|pH reduction, ! purine salvage GO:0043101 8 6 0,000 4,472E-03 0,02103945 ! nucleotide-sugar transmembrane transporter activity GO:0005338 6 6 0,000 4,472E-03 0,02101177 ! neurotrophin binding GO:0043121 6 6 0,000 4,472E-03 0,02098416 ! ciliary rootlet GO:0035253 6 6 0,000 4,472E-03 0,02095662 ! neurotransmitter catabolic process GO:0042135 10 6 0,000 4,472E-03 0,02092915 ! ruffle organization GO:0031529 6 6 0,000 4,472E-03 0,02090176 ! T cell mediated immunity GO:0002456 6 6 0,000 4,472E-03 0,02087443 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 7 6 0,000 4,472E-03 0,02084718 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! carnitine transport GO:0015879 6 6 0,000 4,472E-03 0,02082 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 4,472E-03 0,02079289 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! palmitoyl-CoA hydrolase activity GO:0016290 6 6 0,000 4,472E-03 0,02076585 ! S-methyltransferase activity GO:0008172 6 6 0,000 4,472E-03 0,02073889 ! phospholipase D activity GO:0004630 6 6 0,000 4,472E-03 0,02071199 ! rRNA modification GO:0000154 6 6 0,000 4,472E-03 0,02068516 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 4,472E-03 0,0206584 ! neuronal ion channel clustering GO:0045161 6 6 0,000 4,472E-03 0,02063171 ! response to UV-B GO:0010224 6 6 0,000 4,472E-03 0,02060509 ! interaction with symbiont GO:0051702 6 6 0,000 4,472E-03 0,02057853 ! negative regulation of insulin receptor signaling pathway GO:0046627 6 6 0,000 4,472E-03 0,02055205 ! IgG binding GO:0019864 6 6 0,000 4,472E-03 0,02052563 ! positive regulation of cytokine production during immune response GO:0002720 6 6 0,000 4,472E-03 0,02049928 ! base-excision repair, AP site formation GO:0006285 6 6 0,000 4,472E-03 0,020473 ! benzodiazepine receptor activity GO:0008503 6 6 0,000 4,472E-03 0,02044679 ! response to copper ion GO:0046688 6 6 0,000 4,472E-03 0,02042064 ! DNA topological change GO:0006265 6 6 0,000 4,472E-03 0,02039456 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 4,472E-03 0,02036855 ! dendrite morphogenesis GO:0048813 6 6 0,000 4,472E-03 0,0203426 ! regulation of interleukin-1 beta production GO:0032651 6 6 0,000 4,472E-03 0,02031672 ! regulation of myeloid cell apoptosis GO:0033032 6 6 0,000 4,472E-03 0,02029091 ! positive regulation of tumor necrosis factor production GO:0032760 6 6 0,000 4,472E-03 0,02026516 ! nucleosome disassembly GO:0006337 6 6 0,000 4,472E-03 0,02023947 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! inositol trisphosphate 3-kinase activity GO:0008440 6 6 0,000 4,472E-03 0,02021385 ! regulation of mast cell activation GO:0033003 6 6 0,000 4,472E-03 0,0201883 ! guanylyltransferase activity GO:0070568 6 6 0,000 4,472E-03 0,02016281 ! receptor internalization GO:0031623 7 6 0,000 4,472E-03 0,02013738 ! neuropeptide Y receptor activity GO:0004983 6 6 0,000 4,472E-03 0,02011202 ! ATP-dependent peptidase activity GO:0004176 6 6 0,000 4,472E-03 0,02008672 ! serine-type carboxypeptidase activity GO:0004185 6 6 0,000 4,472E-03 0,02006149 GO:0070008|serine-type exopeptidase activity, ! protein deubiquitination GO:0016579 6 6 0,000 4,472E-03 0,02003631 ! negative regulation of neuroblast proliferation GO:0007406 6 6 0,000 4,472E-03 0,02001121 ! NuRD complex GO:0016581 6 6 0,000 4,472E-03 0,01998616 ! nucleosome positioning GO:0016584 6 6 0,000 4,472E-03 0,01996118 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 4,472E-03 0,01993626 ! alpha-adrenergic receptor activity GO:0004936 8 6 0,000 4,472E-03 0,0199114 ! glycine binding GO:0016594 8 6 0,000 4,472E-03 0,0198866 ! costamere GO:0043034 7 6 0,000 4,472E-03 0,01986187 ! A band GO:0031672 6 6 0,000 4,472E-03 0,0198372 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 4,472E-03 0,01981258 ! dopamine biosynthetic process GO:0042416 7 6 0,000 4,472E-03 0,01978803 ! procollagen-proline dioxygenase activity GO:0019798 6 6 0,000 4,472E-03 0,01976354 ! negative regulation of axon extension GO:0030517 6 6 0,000 4,472E-03 0,01973911 ! actin monomer binding GO:0003785 6 6 0,000 4,472E-03 0,01971474 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 4,472E-03 0,01969043 ! lysozyme activity GO:0003796 6 6 0,000 4,472E-03 0,01966619 ! regulation of Rac protein signal transduction GO:0035020 6 6 0,000 4,472E-03 0,019642 ! ATP catabolic process GO:0006200 6 6 0,000 4,472E-03 0,01961787 ! determination of adult lifespan GO:0008340 6 6 0,000 4,472E-03 0,01959379 ! somatic stem cell maintenance GO:0035019 6 6 0,000 4,472E-03 0,01956978 ! negative regulation of organic acid transport GO:0032891 6 6 0,000 4,472E-03 0,01954583 ! establishment of apical/basal cell polarity GO:0035089 6 6 0,000 4,472E-03 0,01952193 ! calcium-dependent phospholipase A2 activity GO:0047498 6 6 0,000 4,472E-03 0,0194981 ! O-acetyltransferase activity GO:0016413 6 6 0,000 4,472E-03 0,01947432 ! CoA-ligase activity GO:0016405 6 6 0,000 4,472E-03 0,0194506 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 4,472E-03 0,01942694 ! IkappaB kinase complex GO:0008385 6 6 0,000 4,472E-03 0,01940333 ! pyrimidine nucleotide catabolic process GO:0006244 6 6 0,000 4,472E-03 0,01937978 ! store-operated calcium channel activity GO:0015279 6 6 0,000 4,472E-03 0,01935629 ! aminomethyltransferase activity GO:0004047 6 6 0,000 4,472E-03 0,01933286 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 6 6 0,000 4,472E-03 0,01930948 ! alkaline phosphatase activity GO:0004035 6 6 0,000 4,472E-03 0,01928616 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 6 6 0,000 4,472E-03 0,0192629 ! oligosaccharide biosynthetic process GO:0009312 7 7 0,000 5,215E-03 0,02243869 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 5,215E-03 0,02241169 ! sleep GO:0030431 7 7 0,000 5,215E-03 0,02238475 ! synaptonemal complex assembly GO:0007130 7 7 0,000 5,215E-03 0,02235788 GO:0070193|synaptonemal complex organization, ! forebrain regionalization GO:0021871 7 7 0,000 5,215E-03 0,02233107 ! cell proliferation in forebrain GO:0021846 7 7 0,000 5,215E-03 0,02230433 ! proteasome regulatory particle GO:0005838 8 7 0,000 5,215E-03 0,02227765 ! meiotic prophase I GO:0007128 7 7 0,000 5,215E-03 0,02225103 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 7 0,000 5,215E-03 0,02222448 ! SMAD protein nuclear translocation GO:0007184 8 7 0,000 5,215E-03 0,02219799 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 7 7 0,000 5,215E-03 0,02217156 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 5,215E-03 0,0221452 ! diphosphotransferase activity GO:0016778 8 7 0,000 5,215E-03 0,0221189 ! actin-myosin filament sliding GO:0033275 7 7 0,000 5,215E-03 0,02209266 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! signal peptide processing GO:0006465 7 7 0,000 5,215E-03 0,02206648 ! glycine hydroxymethyltransferase activity GO:0004372 8 7 0,000 5,215E-03 0,02204037 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 5,215E-03 0,02201432 ! macrophage chemotaxis GO:0048246 7 7 0,000 5,215E-03 0,02198833 ! cerebral cortex cell migration GO:0021795 7 7 0,000 5,215E-03 0,0219624 ! tachykinin receptor signaling pathway GO:0007217 7 7 0,000 5,215E-03 0,02193653 ! membrane hyperpolarization GO:0060081 7 7 0,000 5,215E-03 0,02191072 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 5,215E-03 0,02188497 ! enoyl-CoA hydratase activity GO:0004300 7 7 0,000 5,215E-03 0,02185929 ! DNA replication origin binding GO:0003688 7 7 0,000 5,215E-03 0,02183366 ! ATPase binding GO:0051117 7 7 0,000 5,215E-03 0,02180809 ! positive regulation of glycolysis GO:0045821 7 7 0,000 5,215E-03 0,02178259 ! positive regulation of isotype switching GO:0045830 11 7 0,000 5,215E-03 0,02175714 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 8 7 0,000 5,215E-03 0,02173175 ! ribonucleoside triphosphate catabolic process GO:0009203 7 7 0,000 5,215E-03 0,02170642 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! protein-cofactor linkage GO:0018065 7 7 0,000 5,215E-03 0,02168116 ! positive regulation of chemokine biosynthetic process GO:0045080 7 7 0,000 5,215E-03 0,02165594 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 7 7 0,000 5,215E-03 0,02163079 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! thymic T cell selection GO:0045061 11 7 0,000 5,215E-03 0,0216057 ! structural constituent of tooth enamel GO:0030345 7 7 0,000 5,215E-03 0,02158066 ! transepithelial chloride transport GO:0030321 7 7 0,000 5,215E-03 0,02155569 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 5,215E-03 0,02153077 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 5,215E-03 0,0215059 ! glycine catabolic process GO:0006546 7 7 0,000 5,215E-03 0,0214811 GO:0009071|serine family amino acid catabolic process, ! deoxyribonucleotide biosynthetic process GO:0009263 8 7 0,000 5,215E-03 0,02145635 ! cytoskeletal anchoring at plasma membrane GO:0007016 8 7 0,000 5,215E-03 0,02143166 ! response to pH GO:0009268 7 7 0,000 5,215E-03 0,02140703 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 5,215E-03 0,02138245 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! polyamine biosynthetic process GO:0006596 7 7 0,000 5,215E-03 0,02135793 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 7 7 0,000 5,215E-03 0,02133346 ! endosome organization GO:0007032 7 7 0,000 5,215E-03 0,02130905 ! thyroid hormone generation GO:0006590 7 7 0,000 5,215E-03 0,0212847 ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 5,215E-03 0,0212604 GO:0021940|positive regulation of granule cell precursor proliferation, ! reverse cholesterol transport GO:0043691 7 7 0,000 5,215E-03 0,02123616 ! tumor necrosis factor receptor activity GO:0005031 7 7 0,000 5,215E-03 0,02121197 ! indolalkylamine metabolic process GO:0006586 7 7 0,000 5,215E-03 0,02118784 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! proton-transporting V-type ATPase, V1 domain GO:0033180 7 7 0,000 5,215E-03 0,02116376 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 5,215E-03 0,02113974 ! retinoid X receptor binding GO:0046965 7 7 0,000 5,215E-03 0,02111577 ! central nervous system neuron axonogenesis GO:0021955 7 7 0,000 5,215E-03 0,02109186 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 5,215E-03 0,021068 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! platelet-derived growth factor receptor activity GO:0005017 7 7 0,000 5,215E-03 0,02104419 ! urea metabolic process GO:0019627 7 7 0,000 5,215E-03 0,02102044 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! retinoic acid receptor signaling pathway GO:0048384 7 7 0,000 5,215E-03 0,02099674 ! regulation of type I interferon production GO:0032479 8 7 0,000 5,215E-03 0,0209731 ! peroxisomal matrix GO:0005782 7 7 0,000 5,215E-03 0,02094951 GO:0031907|microbody lumen, ! methyltransferase complex GO:0034708 7 7 0,000 5,215E-03 0,02092597 GO:0035097|histone methyltransferase complex, ! response to dietary excess GO:0002021 7 7 0,000 5,215E-03 0,02090248 ! p53 binding GO:0002039 7 7 0,000 5,215E-03 0,02087905 ! osteoblast development GO:0002076 8 7 0,000 5,215E-03 0,02085567 ! positive regulation of nitric-oxide synthase activity GO:0051000 7 7 0,000 5,215E-03 0,02083234 ! lipid phosphatase activity GO:0042577 7 7 0,000 5,215E-03 0,02080906 ! male sex determination GO:0030238 7 7 0,000 5,215E-03 0,02078584 ! clathrin binding GO:0030276 8 7 0,000 5,215E-03 0,02076267 ! negative regulation of translational initiation GO:0045947 7 7 0,000 5,215E-03 0,02073955 ! determination of anterior/posterior axis, embryo GO:0008595 7 7 0,000 5,215E-03 0,02071648 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 7 7 0,000 5,215E-03 0,02069346 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 5,215E-03 0,02067049 GO:0030204|chondroitin sulfate metabolic process, ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 5,215E-03 0,02064757 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 5,215E-03 0,02062471 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 5,215E-03 0,02060189 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 5,215E-03 0,02057913 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 8 7 0,000 5,215E-03 0,02055642 ! hyaluronan metabolic process GO:0030212 8 7 0,000 5,215E-03 0,02053375 ! protein retention in ER lumen GO:0006621 7 7 0,000 5,215E-03 0,02051114 ! cardiac muscle cell differentiation GO:0055007 7 7 0,000 5,215E-03 0,02048857 ! peptidyl-arginine modification GO:0018195 7 7 0,000 5,215E-03 0,02046606 ! regulation of circadian rhythm GO:0042752 7 7 0,000 5,215E-03 0,02044359 ! Hsp90 protein binding GO:0051879 7 7 0,000 5,215E-03 0,02042118 ! MutSalpha complex binding GO:0032407 8 7 0,000 5,215E-03 0,02039881 ! regulation of fat cell differentiation GO:0045598 7 7 0,000 5,215E-03 0,02037649 ! establishment of melanosome localization GO:0032401 7 7 0,000 5,215E-03 0,02035422 ! gas homeostasis GO:0033483 7 7 0,000 5,215E-03 0,020332 ! cranial nerve morphogenesis GO:0021602 7 7 0,000 5,215E-03 0,02030983 ! subpallium development GO:0021544 7 7 0,000 5,215E-03 0,0202877 ! laminin-1 complex GO:0005606 7 7 0,000 5,215E-03 0,02026563 GO:0043256|laminin complex, ! molybdopterin cofactor biosynthetic process GO:0032324 7 7 0,000 5,215E-03 0,0202436 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 8 7 0,000 5,215E-03 0,02022162 ! eye photoreceptor cell differentiation GO:0001754 10 7 0,000 5,215E-03 0,02019969 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 7 7 0,000 5,215E-03 0,0201778 ! positive regulation of immunoglobulin mediated immune response GO:0002891 11 7 0,000 5,215E-03 0,02015597 GO:0002714|positive regulation of B cell mediated immunity, ! protein sumoylation GO:0016925 7 7 0,000 5,215E-03 0,02013418 ! establishment of chromosome localization GO:0051303 7 7 0,000 5,215E-03 0,02011243 GO:0050000|chromosome localization, ! regulation of lipid transport GO:0032368 7 7 0,000 5,215E-03 0,02009074 ! regulation of cell division GO:0051302 7 7 0,000 5,215E-03 0,02006909 ! chromatin assembly complex GO:0005678 7 7 0,000 5,215E-03 0,02004748 ! sex chromatin GO:0001739 7 7 0,000 5,215E-03 0,02002593 GO:0000803|sex chromosome, ! oligosaccharyl transferase activity GO:0004576 7 7 0,000 5,215E-03 0,02000442 ! chitinase activity GO:0004568 7 7 0,000 5,215E-03 0,01998295 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 7 7 0,000 5,215E-03 0,01996154 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 7 7 0,000 5,215E-03 0,01994016 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 10 7 0,000 5,215E-03 0,01991884 ! inhibitory MHC class I receptor activity GO:0032396 7 7 0,000 5,215E-03 0,01989756 GO:0030110|HLA-C specific inhibitory MHC class I receptor activity, ! ER to Golgi transport vesicle GO:0030134 7 7 0,000 5,215E-03 0,01987632 ! molybdenum ion binding GO:0030151 7 7 0,000 5,215E-03 0,01985513 ! centriolar satellite GO:0034451 8 7 0,000 5,215E-03 0,01983399 ! positive regulation of epidermis development GO:0045684 7 7 0,000 5,215E-03 0,01981289 ! proteasome regulator activity GO:0010860 7 7 0,000 5,215E-03 0,01979183 ! antibiotic transport GO:0042891 7 7 0,000 5,215E-03 0,01977082 ! negative regulation of transmission of nerve impulse GO:0051970 8 7 0,000 5,215E-03 0,01974985 ! regulation of synaptic transmission, glutamatergic GO:0051966 7 7 0,000 5,215E-03 0,01972893 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 5,215E-03 0,01970806 ! aspartate family amino acid catabolic process GO:0009068 7 7 0,000 5,215E-03 0,01968722 ! Wnt receptor activity GO:0042813 7 7 0,000 5,215E-03 0,01966643 ! regulation of protein homodimerization activity GO:0043496 7 7 0,000 5,215E-03 0,01964569 ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 7 7 0,000 5,215E-03 0,01962499 ! positive regulation of viral reproduction GO:0048524 7 7 0,000 5,215E-03 0,01960433 ! negative regulation of viral reproduction GO:0048525 7 7 0,000 5,215E-03 0,01958371 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 9 7 0,000 5,215E-03 0,01956314 ! blastocyst growth GO:0001832 7 7 0,000 5,215E-03 0,01954262 ! pigment granule transport GO:0051904 7 7 0,000 5,215E-03 0,01952213 ! lymphocyte activation during immune response GO:0002285 7 7 0,000 5,215E-03 0,01950169 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 5,215E-03 0,01948129 ! negative regulation of fibrinolysis GO:0051918 7 7 0,000 5,215E-03 0,01946093 ! negative regulation of telomere maintenance GO:0032205 7 7 0,000 5,215E-03 0,01944062 ! cerebellar cortex formation GO:0021697 8 7 0,000 5,215E-03 0,01942035 ! activation of innate immune response GO:0002218 7 7 0,000 5,215E-03 0,01940012 GO:0002758|innate immune response-activating signal transduction, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 7 7 0,000 5,215E-03 0,01937993 ! natural killer cell mediated immunity GO:0002228 7 7 0,000 5,215E-03 0,01935978 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of synaptic transmission, dopaminergic GO:0032225 7 7 0,000 5,215E-03 0,01933968 ! regulation of synaptic transmission, GABAergic GO:0032228 7 7 0,000 5,215E-03 0,01931962 ! flavin-containing monooxygenase activity GO:0004499 7 7 0,000 5,215E-03 0,0192996 ! regulation of muscle adaptation GO:0043502 7 7 0,000 5,215E-03 0,01927962 ! sequestering of metal ion GO:0051238 7 7 0,000 5,215E-03 0,01925968 ! regulation of T cell receptor signaling pathway GO:0050856 8 7 0,000 5,215E-03 0,01923979 ! membrane attack complex GO:0005579 7 7 0,000 5,215E-03 0,01921993 ! fibrinogen complex GO:0005577 7 7 0,000 5,215E-03 0,01920012 ! septin complex GO:0031105 9 7 0,000 5,215E-03 0,01918034 GO:0032156|septin cytoskeleton, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 7 7 0,000 5,215E-03 0,01916061 ! positive regulation of microtubule polymerization GO:0031116 7 7 0,000 5,215E-03 0,01914092 ! cellular anion homeostasis GO:0030002 7 7 0,000 5,215E-03 0,01912127 GO:0055081|anion homeostasis, ! positive regulation of cyclic nucleotide metabolic process GO:0030801 7 7 0,000 5,215E-03 0,01910165 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! behavioral response to cocaine GO:0048148 9 7 0,000 5,215E-03 0,01908208 ! autophagic vacuole formation GO:0000045 8 7 0,000 5,215E-03 0,01906255 ! negative regulation of smooth muscle cell proliferation GO:0048662 7 7 0,000 5,215E-03 0,01904306 ! translation initiation factor binding GO:0031369 7 7 0,000 5,215E-03 0,01902361 ! regulation of lipid catabolic process GO:0050994 7 7 0,000 5,215E-03 0,0190042 ! activin binding GO:0048185 7 7 0,000 5,215E-03 0,01898482 ! syncytium formation by plasma membrane fusion GO:0000768 7 7 0,000 5,215E-03 0,01896549 GO:0007520|myoblast fusion, ! nucleotide-excision repair, DNA incision GO:0033683 7 7 0,000 5,215E-03 0,0189462 ! oligosaccharyltransferase complex GO:0008250 7 7 0,000 5,215E-03 0,01892694 ! phototransduction, visible light GO:0007603 7 7 0,000 5,215E-03 0,01890773 ! positive regulation of neurotransmitter transport GO:0051590 7 7 0,000 5,215E-03 0,01888855 ! lipoprotein transport GO:0042953 7 7 0,000 5,215E-03 0,01886941 ! cell division site part GO:0032155 7 7 0,000 5,215E-03 0,01885032 GO:0032153|cell division site, ! laminin binding GO:0043236 9 7 0,000 5,215E-03 0,01883126 ! detection of mechanical stimulus involved in sensory perception GO:0050974 7 7 0,000 5,215E-03 0,01881223 ! phospholipid efflux GO:0033700 7 7 0,000 5,215E-03 0,01879325 ! DNA insertion or deletion binding GO:0032135 7 7 0,000 5,215E-03 0,01877431 GO:0032138|single base insertion or deletion binding, ! glucocorticoid metabolic process GO:0008211 7 7 0,000 5,215E-03 0,0187554 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 7 7 0,000 5,215E-03 0,01873653 ! poly-purine tract binding GO:0070717 7 7 0,000 5,215E-03 0,0187177 ! T-helper 1 type immune response GO:0042088 7 7 0,000 5,215E-03 0,01869891 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 5,215E-03 0,01868015 GO:0032107|regulation of response to nutrient levels, ! amyloid precursor protein catabolic process GO:0042987 7 7 0,000 5,215E-03 0,01866144 ! leukocyte degranulation GO:0043299 7 7 0,000 5,215E-03 0,01864275 ! sodium:phosphate symporter activity GO:0005436 7 7 0,000 5,215E-03 0,01862411 ! bile acid and bile salt transport GO:0015721 7 7 0,000 5,215E-03 0,01860551 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 5,215E-03 0,01858694 ! glycerol ether biosynthetic process GO:0046504 7 7 0,000 5,215E-03 0,01856841 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 5,215E-03 0,01854991 GO:0046513|ceramide biosynthetic process, ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 5,215E-03 0,01853145 ! pigment granule organization GO:0048753 7 7 0,000 5,215E-03 0,01851303 ! eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 7 7 0,000 5,215E-03 0,01849465 ! regulation of interleukin-8 biosynthetic process GO:0045414 8 7 0,000 5,215E-03 0,0184763 ! regulation of pigmentation during development GO:0048070 10 7 0,000 5,215E-03 0,01845799 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 7 7 0,000 5,215E-03 0,01843972 ! macrophage activation GO:0042116 7 7 0,000 5,215E-03 0,01842148 ! positive regulation of activated T cell proliferation GO:0042104 7 7 0,000 5,215E-03 0,01840327 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 7 7 0,000 5,215E-03 0,01838511 ! galactose metabolic process GO:0006012 7 7 0,000 5,215E-03 0,01836697 ! vesicle fusion GO:0006906 7 7 0,000 5,215E-03 0,01834888 ! positive regulation of insulin secretion GO:0032024 7 7 0,000 5,215E-03 0,01833082 ! glycerol ether catabolic process GO:0044269 7 7 0,000 5,215E-03 0,01831279 GO:0046464|acylglycerol catabolic process, ! virus-infected cell apoptosis GO:0006926 7 7 0,000 5,215E-03 0,01829481 ! NuA4 histone acetyltransferase complex GO:0035267 8 7 0,000 5,215E-03 0,01827685 ! nucleoside transmembrane transporter activity GO:0005337 7 7 0,000 5,215E-03 0,01825893 GO:0015858|nucleoside transport, ! regulation of vascular permeability GO:0043114 7 7 0,000 5,215E-03 0,01824105 ! regulation of multicellular organismal metabolic process GO:0044246 8 7 0,000 5,215E-03 0,0182232 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 5,215E-03 0,01820539 ! peptidyl-proline dioxygenase activity GO:0031543 7 7 0,000 5,215E-03 0,01818761 ! inclusion body GO:0016234 7 7 0,000 5,215E-03 0,01816987 ! parturition GO:0007567 7 7 0,000 5,215E-03 0,01815216 ! tRNA methyltransferase activity GO:0008175 7 7 0,000 5,215E-03 0,01813448 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 7 7 0,000 5,215E-03 0,01811684 ! intercalated disc GO:0014704 8 7 0,000 5,215E-03 0,01809923 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 5,215E-03 0,01808166 ! neural nucleus development GO:0048857 7 7 0,000 5,215E-03 0,01806412 ! intermediate filament organization GO:0045109 8 7 0,000 5,215E-03 0,01804662 ! skeletal muscle contraction GO:0003009 7 7 0,000 5,215E-03 0,01802915 ! response to antibiotic GO:0046677 7 7 0,000 5,215E-03 0,01801171 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 7 7 0,000 5,215E-03 0,01799431 ! preribosome GO:0030684 7 7 0,000 5,215E-03 0,01797694 ! positive regulation of production of molecular mediator of immune response GO:0002702 7 7 0,000 5,215E-03 0,01795961 ! hydrogen-exporting ATPase activity, phosphorylative mechanism GO:0008553 7 7 0,000 5,215E-03 0,0179423 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 7 7 0,000 5,215E-03 0,01792504 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 5,215E-03 0,0179078 ! regulation of interleukin-1 production GO:0032652 7 7 0,000 5,215E-03 0,0178906 ! phosphofructokinase activity GO:0008443 7 7 0,000 5,215E-03 0,01787343 ! postreplication repair GO:0006301 7 7 0,000 5,215E-03 0,01785629 ! gap junction channel activity GO:0005243 7 7 0,000 5,215E-03 0,01783919 ! transcription from RNA polymerase I promoter GO:0006360 7 7 0,000 5,215E-03 0,01782212 ! mitochondrion morphogenesis GO:0070584 8 7 0,000 5,215E-03 0,01780508 ! transcription termination GO:0006353 8 7 0,000 5,215E-03 0,01778807 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 7 7 0,000 5,215E-03 0,0177711 ! tetracycline transporter activity GO:0008493 7 7 0,000 5,215E-03 0,01775416 GO:0042895|antibiotic transporter activity, ! cytidylyltransferase activity GO:0070567 7 7 0,000 5,215E-03 0,01773725 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 5,215E-03 0,01772037 ! melanocortin receptor activity GO:0004977 7 7 0,000 5,215E-03 0,01770353 ! coenzyme A metabolic process GO:0015936 8 7 0,000 5,215E-03 0,01768672 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 7 0,000 5,215E-03 0,01766994 ! regulation of macrophage activation GO:0043030 7 7 0,000 5,215E-03 0,01765319 ! cytidine deaminase activity GO:0004126 7 7 0,000 5,215E-03 0,01763647 ! inositol trisphosphate kinase activity GO:0051766 7 7 0,000 5,215E-03 0,01761978 ! apical protein localization GO:0045176 7 7 0,000 5,215E-03 0,01760313 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 5,215E-03 0,01758651 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 5,215E-03 0,01756992 ! virion binding GO:0046790 10 7 0,000 5,215E-03 0,01755336 ! nonprotein amino acid metabolic process GO:0019794 7 7 0,000 5,215E-03 0,01753683 ! protein prenyltransferase activity GO:0008318 7 7 0,000 5,215E-03 0,01752033 ! protein modification by small protein removal GO:0070646 7 7 0,000 5,215E-03 0,01750386 ! adult feeding behavior GO:0008343 7 7 0,000 5,215E-03 0,01748743 ! CoA carboxylase activity GO:0016421 7 7 0,000 5,215E-03 0,01747102 ! microtubule basal body GO:0005932 7 7 0,000 5,215E-03 0,01745465 ! positive regulation of NF-kappaB import into nucleus GO:0042346 7 7 0,000 5,215E-03 0,01743831 ! embryonic heart tube development GO:0035050 7 7 0,000 5,215E-03 0,01742199 ! kainate selective glutamate receptor activity GO:0015277 7 7 0,000 5,215E-03 0,01740571 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 5,215E-03 0,01738946 ! positive regulation of smooth muscle contraction GO:0045987 7 7 0,000 5,215E-03 0,01737324 ! rRNA transcription GO:0009303 8 8 0,000 5,958E-03 0,0198299 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 8 8 0,000 5,958E-03 0,01981143 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 5,958E-03 0,019793 ! sodium:hydrogen antiporter activity GO:0015385 8 8 0,000 5,958E-03 0,01977461 GO:0005451|monovalent cation:hydrogen antiporter activity, ! negative regulation of lipid biosynthetic process GO:0051055 9 8 0,000 5,958E-03 0,01975625 ! cation:chloride symporter activity GO:0015377 9 8 0,000 5,958E-03 0,01973792 ! positive regulation of small GTPase mediated signal transduction GO:0051057 8 8 0,000 5,958E-03 0,01971963 GO:0046579|positive regulation of Ras protein signal transduction, ! forebrain neuron differentiation GO:0021879 9 8 0,000 5,958E-03 0,01970137 ! male meiosis GO:0007140 8 8 0,000 5,958E-03 0,01968314 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 8 8 0,000 5,958E-03 0,01966495 ! N-glycan processing GO:0006491 8 8 0,000 5,958E-03 0,0196468 ! regulation of smooth muscle cell migration GO:0014910 9 8 0,000 5,958E-03 0,01962867 ! protein self-association GO:0043621 8 8 0,000 5,958E-03 0,01961058 ! RNA methylation GO:0001510 8 8 0,000 5,958E-03 0,01959252 ! prostaglandin biosynthetic process GO:0001516 9 8 0,000 5,958E-03 0,0195745 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 8 8 0,000 5,958E-03 0,01955651 ! regulation of activated T cell proliferation GO:0046006 8 8 0,000 5,958E-03 0,01953855 ! hexokinase activity GO:0004396 8 8 0,000 5,958E-03 0,01952062 ! neurofilament cytoskeleton GO:0060053 8 8 0,000 5,958E-03 0,01950273 ! guanylate cyclase activity GO:0004383 8 8 0,000 5,958E-03 0,01948487 ! integral to mitochondrial membrane GO:0032592 8 8 0,000 5,958E-03 0,01946704 ! troponin complex GO:0005861 9 8 0,000 5,958E-03 0,01944925 ! smoothened signaling pathway GO:0007224 8 8 0,000 5,958E-03 0,01943149 ! negative regulation of muscle cell differentiation GO:0051148 8 8 0,000 5,958E-03 0,01941376 ! ganglioside metabolic process GO:0001573 8 8 0,000 5,958E-03 0,01939606 ! reflex GO:0060004 11 8 0,000 5,958E-03 0,0193784 ! small protein activating enzyme activity GO:0008641 10 8 0,000 5,958E-03 0,01936076 ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 5,958E-03 0,01934316 ! hemoglobin metabolic process GO:0020027 8 8 0,000 5,958E-03 0,01932559 ! protein targeting to ER GO:0045047 9 8 0,000 5,958E-03 0,01930806 ! positive regulation of survival gene product expression GO:0045885 8 8 0,000 5,958E-03 0,01929055 ! arginine catabolic process GO:0006527 8 8 0,000 5,958E-03 0,01927308 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 5,958E-03 0,01925564 ! malate dehydrogenase activity GO:0016615 8 8 0,000 5,958E-03 0,01923823 ! inner mitochondrial membrane organization GO:0007007 9 8 0,000 5,958E-03 0,01922085 ! telomere maintenance via telomerase GO:0007004 8 8 0,000 5,958E-03 0,0192035 GO:0010833|telomere maintenance via telomere lengthening, ! DNA secondary structure binding GO:0000217 8 8 0,000 5,958E-03 0,01918618 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 9 8 0,000 5,958E-03 0,0191689 ! proline metabolic process GO:0006560 9 8 0,000 5,958E-03 0,01915165 ! melanosome membrane GO:0033162 10 8 0,000 5,958E-03 0,01913442 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 5,958E-03 0,01911723 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 5,958E-03 0,01910007 ! melanin metabolic process GO:0006582 9 8 0,000 5,958E-03 0,01908294 ! death receptor activity GO:0005035 8 8 0,000 5,958E-03 0,01906584 ! Golgi lumen GO:0005796 8 8 0,000 5,958E-03 0,01904877 ! smooth endoplasmic reticulum GO:0005790 9 8 0,000 5,958E-03 0,01903173 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 5,958E-03 0,01901473 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 9 8 0,000 5,958E-03 0,01899775 GO:0048500|signal recognition particle, ! Golgi cisterna GO:0031985 9 8 0,000 5,958E-03 0,0189808 ! positive regulation of mesenchymal cell proliferation GO:0002053 8 8 0,000 5,958E-03 0,01896389 ! Rac protein signal transduction GO:0016601 8 8 0,000 5,958E-03 0,018947 ! positive regulation of calcium ion transport into cytosol GO:0010524 11 8 0,000 5,958E-03 0,01893014 ! lens development in camera-type eye GO:0002088 8 8 0,000 5,958E-03 0,01891331 ! positive regulation of vasodilation GO:0045909 8 8 0,000 5,958E-03 0,01889652 ! intestinal cholesterol absorption GO:0030299 8 8 0,000 5,958E-03 0,01887975 ! negative regulation of muscle contraction GO:0045932 9 8 0,000 5,958E-03 0,01886301 ! positive regulation vascular endothelial growth factor production GO:0010575 8 8 0,000 5,958E-03 0,01884631 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 8 8 0,000 5,958E-03 0,01882963 ! Schwann cell differentiation GO:0014037 8 8 0,000 5,958E-03 0,01881298 ! sodium:dicarboxylate symporter activity GO:0017153 8 8 0,000 5,958E-03 0,01879636 ! axon guidance receptor activity GO:0008046 8 8 0,000 5,958E-03 0,01877977 ! protein targeting to vacuole GO:0006623 8 8 0,000 5,958E-03 0,01876321 ! response to tropane GO:0014073 10 8 0,000 5,958E-03 0,01874668 GO:0042220|response to cocaine, ! purine nucleoside triphosphate catabolic process GO:0009146 8 8 0,000 5,958E-03 0,01873018 ! melanosome localization GO:0032400 8 8 0,000 5,958E-03 0,0187137 ! response to amine stimulus GO:0014075 10 8 0,000 5,958E-03 0,01869726 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 8 8 0,000 5,958E-03 0,01868084 ! sphingomyelin metabolic process GO:0006684 9 8 0,000 5,958E-03 0,01866446 ! regulation of mitochondrial membrane potential GO:0051881 8 8 0,000 5,958E-03 0,0186481 ! synaptic vesicle endocytosis GO:0048488 8 8 0,000 5,958E-03 0,01863177 ! holo TFIIH complex GO:0005675 8 8 0,000 5,958E-03 0,01861547 ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 5,958E-03 0,0185992 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 8 0,000 5,958E-03 0,01858295 ! negative regulation of cytokine secretion GO:0050710 8 8 0,000 5,958E-03 0,01856674 ! regulation of myoblast differentiation GO:0045661 8 8 0,000 5,958E-03 0,01855055 ! vitamin transporter activity GO:0051183 8 8 0,000 5,958E-03 0,01853439 ! positive regulation of erythrocyte differentiation GO:0045648 8 8 0,000 5,958E-03 0,01851826 ! neuromuscular process controlling posture GO:0050884 8 8 0,000 5,958E-03 0,01850216 ! heparan sulfate sulfotransferase activity GO:0034483 8 8 0,000 5,958E-03 0,01848608 ! regulation of epidermal cell differentiation GO:0045604 8 8 0,000 5,958E-03 0,01847003 ! regulation of T-helper 2 cell differentiation GO:0045628 8 8 0,000 5,958E-03 0,01845401 ! positive regulation of T-helper cell differentiation GO:0045624 8 8 0,000 5,958E-03 0,01843802 ! branched chain family amino acid catabolic process GO:0009083 8 8 0,000 5,958E-03 0,01842206 ! regulation of synaptogenesis GO:0051963 8 8 0,000 5,958E-03 0,01840612 ! oocyte differentiation GO:0009994 8 8 0,000 5,958E-03 0,01839022 GO:0048599|oocyte development, ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 8 8 0,000 5,958E-03 0,01837433 GO:0003756|protein disulfide isomerase activity, ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 5,958E-03 0,01835848 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 8 0,000 5,958E-03 0,01834265 ! beta-1,3-galactosyltransferase activity GO:0048531 8 8 0,000 5,958E-03 0,01832686 ! establishment of pigment granule localization GO:0051905 8 8 0,000 5,958E-03 0,01831108 ! regulation of telomere maintenance GO:0032204 8 8 0,000 5,958E-03 0,01829534 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 5,958E-03 0,01827962 ! amino sugar catabolic process GO:0046348 8 8 0,000 5,958E-03 0,01826393 GO:0006043|glucosamine catabolic process, ! regulation of amino acid transport GO:0051955 8 8 0,000 5,958E-03 0,01824827 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 5,958E-03 0,01823263 ! T cell receptor signaling pathway GO:0050852 13 8 0,000 5,958E-03 0,01821702 ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 8 0,000 5,958E-03 0,01820144 ! cholesterol transporter activity GO:0017127 8 8 0,000 5,958E-03 0,01818588 ! GABA receptor binding GO:0050811 8 8 0,000 5,958E-03 0,01817035 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 8 8 0,000 5,958E-03 0,01815485 ! regulation of microtubule polymerization GO:0031113 8 8 0,000 5,958E-03 0,01813937 ! regulation of developmental growth GO:0048638 8 8 0,000 5,958E-03 0,01812392 ! GMP binding GO:0019002 10 8 0,000 5,958E-03 0,01810849 GO:0030553|cGMP binding, ! regulation of epithelial cell differentiation GO:0030856 8 8 0,000 5,958E-03 0,01809309 ! negative regulation of cellular catabolic process GO:0031330 9 8 0,000 5,958E-03 0,01807772 ! prostate gland development GO:0030850 8 8 0,000 5,958E-03 0,01806238 ! 7S RNA binding GO:0008312 9 8 0,000 5,958E-03 0,01804706 ! phosphate transport GO:0006817 9 8 0,000 5,958E-03 0,01803176 ! neutral lipid catabolic process GO:0046461 8 8 0,000 5,958E-03 0,01801649 ! protein phosphorylated amino acid binding GO:0045309 10 8 0,000 5,958E-03 0,01800125 ! reproductive behavior GO:0019098 8 8 0,000 5,958E-03 0,01798603 ! cell volume homeostasis GO:0006884 9 8 0,000 5,958E-03 0,01797084 ! regulation of long-term neuronal synaptic plasticity GO:0048169 8 8 0,000 5,958E-03 0,01795568 ! oligopeptide transport GO:0006857 8 8 0,000 5,958E-03 0,01794054 GO:0015198|oligopeptide transporter activity, ! induction of positive chemotaxis GO:0050930 8 8 0,000 5,958E-03 0,01792542 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 5,958E-03 0,01791034 ! regulation of dopamine metabolic process GO:0042053 8 8 0,000 5,958E-03 0,01789527 GO:0042069|regulation of catecholamine metabolic process, ! regulation of carbohydrate biosynthetic process GO:0043255 8 8 0,000 5,958E-03 0,01788023 ! titin binding GO:0031432 8 8 0,000 5,958E-03 0,01786522 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 5,958E-03 0,01785023 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 8 0,000 5,958E-03 0,01783527 ! bone resorption GO:0045453 8 8 0,000 5,958E-03 0,01782033 ! glycerolipid catabolic process GO:0046503 8 8 0,000 5,958E-03 0,01780542 ! endoderm development GO:0007492 8 8 0,000 5,958E-03 0,01779053 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 5,958E-03 0,01777567 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 5,958E-03 0,01776083 ! astrocyte differentiation GO:0048708 8 8 0,000 5,958E-03 0,01774602 ! embryonic cranial skeleton morphogenesis GO:0048701 8 8 0,000 5,958E-03 0,01773123 ! syncytium formation GO:0006949 8 8 0,000 5,958E-03 0,01771647 ! embryonic eye morphogenesis GO:0048048 10 8 0,000 5,958E-03 0,01770173 ! B cell proliferation GO:0042100 8 8 0,000 5,958E-03 0,01768702 ! mannose metabolic process GO:0006013 10 8 0,000 5,958E-03 0,01767232 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 8 8 0,000 5,958E-03 0,01765766 ! asymmetric protein localization GO:0008105 8 8 0,000 5,958E-03 0,01764302 ! tumor necrosis factor binding GO:0043120 8 8 0,000 5,958E-03 0,0176284 ! synaptic transmission, glutamatergic GO:0035249 9 8 0,000 5,958E-03 0,01761381 ! neuron apoptosis GO:0051402 8 8 0,000 5,958E-03 0,01759924 ! macroautophagy GO:0016236 9 8 0,000 5,958E-03 0,01758469 ! Cajal body GO:0015030 8 8 0,000 5,958E-03 0,01757017 ! O-methyltransferase activity GO:0008171 9 8 0,000 5,958E-03 0,01755568 ! H4/H2A histone acetyltransferase complex GO:0043189 9 8 0,000 5,958E-03 0,0175412 ! PcG protein complex GO:0031519 8 8 0,000 5,958E-03 0,01752675 ! ferric iron binding GO:0008199 9 8 0,000 5,958E-03 0,01751233 ! spindle checkpoint GO:0031577 8 8 0,000 5,958E-03 0,01749793 ! G1 DNA damage checkpoint GO:0031571 8 8 0,000 5,958E-03 0,01748355 ! segment specification GO:0007379 8 8 0,000 5,958E-03 0,01746919 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 5,958E-03 0,01745486 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 5,958E-03 0,01744056 ! cellular extravasation GO:0045123 9 8 0,000 5,958E-03 0,01742627 ! pronucleus GO:0045120 8 8 0,000 5,958E-03 0,01741201 ! regulation of insulin receptor signaling pathway GO:0046626 8 8 0,000 5,958E-03 0,01739778 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 8 8 0,000 5,958E-03 0,01738356 ! Rac GTPase activator activity GO:0030675 9 8 0,000 5,958E-03 0,01736937 ! regulation of DNA repair GO:0006282 8 8 0,000 5,958E-03 0,0173552 ! transcription-coupled nucleotide-excision repair GO:0006283 9 8 0,000 5,958E-03 0,01734106 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 5,958E-03 0,01732694 ! antigen processing and presentation of exogenous antigen GO:0019884 9 8 0,000 5,958E-03 0,01731284 ! DNA ligation GO:0006266 8 8 0,000 5,958E-03 0,01729876 ! regulation of T cell differentiation in the thymus GO:0033081 8 8 0,000 5,958E-03 0,01728471 ! negative regulation of systemic arterial blood pressure GO:0003085 8 8 0,000 5,958E-03 0,01727068 ! multicellular organismal aging GO:0010259 8 8 0,000 5,958E-03 0,01725667 ! erythrocyte development GO:0048821 8 8 0,000 5,958E-03 0,01724269 ! interleukin-1 receptor activity GO:0004908 8 8 0,000 5,958E-03 0,01722873 ! positive regulation of monooxygenase activity GO:0032770 8 8 0,000 5,958E-03 0,01721479 ! protein import into peroxisome matrix GO:0016558 8 8 0,000 5,958E-03 0,01720087 ! gamma-tubulin binding GO:0043015 8 8 0,000 5,958E-03 0,01718698 ! ribosome binding GO:0043022 9 8 0,000 5,958E-03 0,01717311 ! NADPH oxidase complex GO:0043020 8 8 0,000 5,958E-03 0,01715926 ! mRNA polyadenylation GO:0006378 8 8 0,000 5,958E-03 0,01714543 ! sodium:amino acid symporter activity GO:0005283 8 8 0,000 5,958E-03 0,01713163 ! adenylyltransferase activity GO:0070566 8 8 0,000 5,958E-03 0,01711784 ! zymogen activation GO:0031638 8 8 0,000 5,958E-03 0,01710408 ! axonal fasciculation GO:0007413 8 8 0,000 5,958E-03 0,01709034 ! negative regulation of nuclear division GO:0051784 8 8 0,000 5,958E-03 0,01707663 GO:0045839|negative regulation of mitosis, ! caspase inhibitor activity GO:0043027 8 8 0,000 5,958E-03 0,01706293 ! energy coupled proton transport, against electrochemical gradient GO:0015988 8 8 0,000 5,958E-03 0,01704926 GO:0015991|ATP hydrolysis coupled proton transport, ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 8 8 0,000 5,958E-03 0,01703561 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 5,958E-03 0,01702198 ! thyroid hormone receptor activity GO:0004887 8 8 0,000 5,958E-03 0,01700838 ! wide pore channel activity GO:0022829 8 8 0,000 5,958E-03 0,01699479 ! ligand-regulated transcription factor activity GO:0003706 8 8 0,000 5,958E-03 0,01698123 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 5,958E-03 0,01696769 ! hormone catabolic process GO:0042447 8 8 0,000 5,958E-03 0,01695417 ! positive regulation of ATPase activity GO:0032781 8 8 0,000 5,958E-03 0,01694067 ! biogenic amine catabolic process GO:0042402 11 8 0,000 5,958E-03 0,01692719 ! Notch binding GO:0005112 8 8 0,000 5,958E-03 0,01691374 ! death receptor binding GO:0005123 8 8 0,000 5,958E-03 0,0169003 ! ATPase regulator activity GO:0060590 8 8 0,000 5,958E-03 0,01688689 ! pyrimidine base metabolic process GO:0006206 10 8 0,000 5,958E-03 0,0168735 ! epidermal growth factor receptor binding GO:0005154 9 8 0,000 5,958E-03 0,01686013 ! dihydropyridine-sensitive calcium channel activity GO:0015270 8 8 0,000 5,958E-03 0,01684678 ! calcium-release channel activity GO:0015278 8 8 0,000 5,958E-03 0,01683345 ! tubulin-tyrosine ligase activity GO:0004835 8 8 0,000 5,958E-03 0,01682014 ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 5,958E-03 0,01680686 ! nucleus localization GO:0051647 10 8 0,000 5,958E-03 0,01679359 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 5,958E-03 0,01678035 ! negative regulation of immune effector process GO:0002698 12 8 0,000 5,958E-03 0,01676712 ! C-X-C chemokine receptor activity GO:0016494 8 8 0,000 5,958E-03 0,01675392 ! adenosine deaminase activity GO:0004000 8 8 0,000 5,958E-03 0,01674074 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 9 9 0,000 6,701E-03 0,01881214 ! respiratory burst GO:0045730 9 9 0,000 6,701E-03 0,01879736 ! telencephalon cell migration GO:0022029 9 9 0,000 6,701E-03 0,01878261 ! 'de novo' posttranslational protein folding GO:0051084 9 9 0,000 6,701E-03 0,01876788 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 6,701E-03 0,01875317 ! cGMP metabolic process GO:0046068 9 9 0,000 6,701E-03 0,01873848 GO:0006182|cGMP biosynthetic process, ! regulation of epidermal growth factor receptor activity GO:0007176 9 9 0,000 6,701E-03 0,01872382 GO:0010469|regulation of receptor activity, ! inositol trisphosphate phosphatase activity GO:0046030 11 9 0,000 6,701E-03 0,01870918 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! axon part GO:0033267 12 9 0,000 6,701E-03 0,01869457 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 9 9 0,000 6,701E-03 0,01867997 ! RNA polyadenylation GO:0043631 9 9 0,000 6,701E-03 0,0186654 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 9 0,000 6,701E-03 0,01865085 ! regulation of receptor-mediated endocytosis GO:0048259 9 9 0,000 6,701E-03 0,01863633 ! artery development GO:0060840 9 9 0,000 6,701E-03 0,01862182 GO:0048844|artery morphogenesis, ! photoreceptor cell development GO:0042461 12 9 0,000 6,701E-03 0,01860734 GO:0046530|photoreceptor cell differentiation, ! microtubule bundle formation GO:0001578 9 9 0,000 6,701E-03 0,01859289 ! regulation of mesenchymal cell proliferation GO:0010464 9 9 0,000 6,701E-03 0,01857845 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 12 9 0,000 6,701E-03 0,01856404 GO:0046330|positive regulation of JNK cascade, ! positive regulation of heart contraction GO:0045823 10 9 0,000 6,701E-03 0,01854965 ! lung alveolus development GO:0048286 9 9 0,000 6,701E-03 0,01853528 ! ciliary or flagellar motility GO:0001539 9 9 0,000 6,701E-03 0,01852093 ! beta-amyloid binding GO:0001540 10 9 0,000 6,701E-03 0,01850661 ! pathogenesis GO:0009405 9 9 0,000 6,701E-03 0,01849231 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 10 9 0,000 6,701E-03 0,01847803 ! regulated secretory pathway GO:0045055 9 9 0,000 6,701E-03 0,01846377 ! regulation of S phase of mitotic cell cycle GO:0007090 9 9 0,000 6,701E-03 0,01844953 ! estrogen receptor binding GO:0030331 9 9 0,000 6,701E-03 0,01843532 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 10 9 0,000 6,701E-03 0,01842113 ! regulation of defense response to virus by virus GO:0050690 9 9 0,000 6,701E-03 0,01840696 ! histidine metabolic process GO:0006547 9 9 0,000 6,701E-03 0,01839281 GO:0009075|histidine family amino acid metabolic process, ! L-phenylalanine metabolic process GO:0006558 10 9 0,000 6,701E-03 0,01837868 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 9 9 0,000 6,701E-03 0,01836458 GO:0005978|glycogen biosynthetic process, ! V(D)J recombination GO:0033151 9 9 0,000 6,701E-03 0,01835049 ! nucleobase biosynthetic process GO:0046112 11 9 0,000 6,701E-03 0,01833643 ! regulation of Cdc42 protein signal transduction GO:0032489 9 9 0,000 6,701E-03 0,01832239 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of calcium ion transport into cytosol GO:0010522 12 9 0,000 6,701E-03 0,01830837 ! entry into host cell GO:0030260 9 9 0,000 6,701E-03 0,01829438 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 9 9 0,000 6,701E-03 0,0182804 ! regulation of lipoprotein lipase activity GO:0051004 9 9 0,000 6,701E-03 0,01826645 ! retinoic acid metabolic process GO:0042573 9 9 0,000 6,701E-03 0,01825251 ! retinol metabolic process GO:0042572 9 9 0,000 6,701E-03 0,0182386 ! behavioral fear response GO:0001662 9 9 0,000 6,701E-03 0,01822471 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 10 9 0,000 6,701E-03 0,01821084 ! regulation of vascular endothelial growth factor production GO:0010574 9 9 0,000 6,701E-03 0,01819699 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 9 9 0,000 6,701E-03 0,01818316 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! motor axon guidance GO:0008045 9 9 0,000 6,701E-03 0,01816936 ! regulation of gliogenesis GO:0014013 9 9 0,000 6,701E-03 0,01815557 GO:0045685|regulation of glial cell differentiation, ! recycling endosome membrane GO:0055038 10 9 0,000 6,701E-03 0,01814181 ! pigment granule localization GO:0051875 9 9 0,000 6,701E-03 0,01812806 ! platelet-derived growth factor binding GO:0048407 10 9 0,000 6,701E-03 0,01811434 ! glycosphingolipid biosynthetic process GO:0006688 9 9 0,000 6,701E-03 0,01810064 ! nucleoside diphosphate metabolic process GO:0009132 10 9 0,000 6,701E-03 0,01808696 ! phosphoinositide 3-kinase cascade GO:0014065 9 9 0,000 6,701E-03 0,0180733 ! cell wall macromolecule catabolic process GO:0016998 10 9 0,000 6,701E-03 0,01805966 ! purine ribonucleotide catabolic process GO:0009154 9 9 0,000 6,701E-03 0,01804604 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 9 9 0,000 6,701E-03 0,01803244 ! nitric oxide metabolic process GO:0046209 9 9 0,000 6,701E-03 0,01801886 GO:0006809|nitric oxide biosynthetic process, ! mismatch repair complex GO:0032300 9 9 0,000 6,701E-03 0,0180053 ! icosanoid secretion GO:0032309 9 9 0,000 6,701E-03 0,01799176 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 10 9 0,000 6,701E-03 0,01797825 GO:0010092|specification of organ identity, ! retinal ganglion cell axon guidance GO:0031290 9 9 0,000 6,701E-03 0,01796475 ! morphogenesis of a polarized epithelium GO:0001738 9 9 0,000 6,701E-03 0,01795127 ! sterol catabolic process GO:0016127 9 9 0,000 6,701E-03 0,01793781 GO:0006707|cholesterol catabolic process, ! prophase GO:0051324 9 9 0,000 6,701E-03 0,01792438 ! peptidyl-lysine modification GO:0018205 9 9 0,000 6,701E-03 0,01791096 ! pancreatic ribonuclease activity GO:0004522 9 9 0,000 6,701E-03 0,01789756 ! clathrin coat of coated pit GO:0030132 12 9 0,000 6,701E-03 0,01788419 ! SNARE complex GO:0031201 10 9 0,000 6,701E-03 0,01787083 ! ubiquinone metabolic process GO:0006743 10 9 0,000 6,701E-03 0,0178575 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! snRNA binding GO:0017069 9 9 0,000 6,701E-03 0,01784418 ! regulation of macrophage differentiation GO:0045649 9 9 0,000 6,701E-03 0,01783088 ! regulation of osteoclast differentiation GO:0045670 10 9 0,000 6,701E-03 0,01781761 ! positive regulation of neuron differentiation GO:0045666 9 9 0,000 6,701E-03 0,01780435 ! negative regulation of lymphocyte differentiation GO:0045620 9 9 0,000 6,701E-03 0,01779111 ! methionine biosynthetic process GO:0009086 10 9 0,000 6,701E-03 0,01777789 ! peptidoglycan binding GO:0042834 9 9 0,000 6,701E-03 0,0177647 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 6,701E-03 0,01775152 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! pyridine nucleotide biosynthetic process GO:0019363 9 9 0,000 6,701E-03 0,01773836 ! intramolecular transferase activity, phosphotransferases GO:0016868 9 9 0,000 6,701E-03 0,01772522 ! cholesterol efflux GO:0033344 9 9 0,000 6,701E-03 0,0177121 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 9 9 0,000 6,701E-03 0,017699 ! metalloenzyme inhibitor activity GO:0048551 10 9 0,000 6,701E-03 0,01768592 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! leukocyte mediated cytotoxicity GO:0001909 9 9 0,000 6,701E-03 0,01767285 ! anterior/posterior axis specification GO:0009948 9 9 0,000 6,701E-03 0,01765981 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 6,701E-03 0,01764679 ! detection of calcium ion GO:0005513 10 9 0,000 6,701E-03 0,01763378 ! negative regulation of glucose import GO:0046325 9 9 0,000 6,701E-03 0,0176208 GO:0010829|negative regulation of glucose transport, ! regulation of fibrinolysis GO:0051917 9 9 0,000 6,701E-03 0,01760783 ! trophectodermal cell differentiation GO:0001829 9 9 0,000 6,701E-03 0,01759489 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 9 0,000 6,701E-03 0,01758196 ! hydrolase activity, acting on ether bonds GO:0016801 9 9 0,000 6,701E-03 0,01756905 ! desmosome GO:0030057 9 9 0,000 6,701E-03 0,01755616 ! prepulse inhibition GO:0060134 9 9 0,000 6,701E-03 0,01754329 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 9 0,000 6,701E-03 0,01753044 ! negative regulation of B cell activation GO:0050869 9 9 0,000 6,701E-03 0,0175176 ! anchoring collagen GO:0030934 9 9 0,000 6,701E-03 0,01750479 ! axon extension GO:0048675 10 9 0,000 6,701E-03 0,01749199 ! neuron fate specification GO:0048665 9 9 0,000 6,701E-03 0,01747921 ! positive regulation of glucose metabolic process GO:0010907 9 9 0,000 6,701E-03 0,01746646 ! cortical actin cytoskeleton organization GO:0030866 9 9 0,000 6,701E-03 0,01745372 ! virus-host interaction GO:0019048 13 9 0,000 6,701E-03 0,01744099 ! rough endoplasmic reticulum membrane GO:0030867 9 9 0,000 6,701E-03 0,01742829 ! pentose-phosphate shunt GO:0006098 9 9 0,000 6,701E-03 0,01741561 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 6,701E-03 0,01740294 ! DNA bending activity GO:0008301 9 9 0,000 6,701E-03 0,01739029 ! social behavior GO:0035176 9 9 0,000 6,701E-03 0,01737766 ! secondary active sulfate transmembrane transporter activity GO:0008271 9 9 0,000 6,701E-03 0,01736505 ! dipeptidyl-peptidase activity GO:0008239 11 9 0,000 6,701E-03 0,01735246 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 6,701E-03 0,01733989 ! very-low-density lipoprotein particle GO:0034361 9 9 0,000 6,701E-03 0,01732733 GO:0034385|triglyceride-rich lipoprotein particle, ! high-density lipoprotein particle GO:0034364 9 9 0,000 6,701E-03 0,01731479 ! amyloid precursor protein metabolic process GO:0042982 10 9 0,000 6,701E-03 0,01730227 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 11 9 0,000 6,701E-03 0,01728977 ! blood vessel remodeling GO:0001974 10 9 0,000 6,701E-03 0,01727729 ! C-X-C chemokine binding GO:0019958 9 9 0,000 6,701E-03 0,01726482 ! 3'-5'-exoribonuclease activity GO:0000175 9 9 0,000 6,701E-03 0,01725238 ! exosome (RNase complex) GO:0000178 9 9 0,000 6,701E-03 0,01723995 ! inositol phosphate-mediated signaling GO:0048016 9 9 0,000 6,701E-03 0,01722753 ! DNA N-glycosylase activity GO:0019104 9 9 0,000 6,701E-03 0,01721514 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 9 9 0,000 6,701E-03 0,01720276 GO:0033549|MAP kinase phosphatase activity, ! ER overload response GO:0006983 11 9 0,000 6,701E-03 0,01719041 ! zinc ion transmembrane transporter activity GO:0005385 9 9 0,000 6,701E-03 0,01717806 ! glucose transmembrane transporter activity GO:0005355 9 9 0,000 6,701E-03 0,01716574 ! retrograde transport, endosome to Golgi GO:0042147 10 9 0,000 6,701E-03 0,01715344 ! phagocytosis, engulfment GO:0006911 10 9 0,000 6,701E-03 0,01714115 ! neurotransmitter biosynthetic process GO:0042136 10 9 0,000 6,701E-03 0,01712888 ! carbohydrate phosphatase activity GO:0019203 9 9 0,000 6,701E-03 0,01711663 ! glutathione peroxidase activity GO:0004602 9 9 0,000 6,701E-03 0,01710439 ! acyl-CoA thioesterase activity GO:0016291 9 9 0,000 6,701E-03 0,01709217 ! lysophospholipase activity GO:0004622 9 9 0,000 6,701E-03 0,01707997 ! brain morphogenesis GO:0048854 9 9 0,000 6,701E-03 0,01706779 ! apolipoprotein binding GO:0034185 9 9 0,000 6,701E-03 0,01705563 ! synaptic vesicle membrane GO:0030672 9 9 0,000 6,701E-03 0,01704348 ! RNA-dependent DNA replication GO:0006278 9 9 0,000 6,701E-03 0,01703135 ! positive regulation of systemic arterial blood pressure GO:0003084 10 9 0,000 6,701E-03 0,01701923 ! kinesin binding GO:0019894 9 9 0,000 6,701E-03 0,01700714 ! nucleoside bisphosphate metabolic process GO:0033865 10 9 0,000 6,701E-03 0,01699506 ! renal water homeostasis GO:0003091 9 9 0,000 6,701E-03 0,016983 ! positive regulation of interleukin-6 production GO:0032755 9 9 0,000 6,701E-03 0,01697095 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 6,701E-03 0,01695893 ! histone methylation GO:0016571 10 9 0,000 6,701E-03 0,01694692 ! mRNA cleavage GO:0006379 9 9 0,000 6,701E-03 0,01693492 ! negative regulation of tumor necrosis factor production GO:0032720 9 9 0,000 6,701E-03 0,01692295 ! regulation of transcription from RNA polymerase III promoter GO:0006359 9 9 0,000 6,701E-03 0,01691099 ! sarcoplasmic reticulum membrane GO:0033017 10 9 0,000 6,701E-03 0,01689904 ! opioid receptor activity GO:0004985 9 9 0,000 6,701E-03 0,01688712 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 6,701E-03 0,01687521 ! salivary gland development GO:0007431 10 9 0,000 6,701E-03 0,01686332 ! glucosidase activity GO:0015926 10 9 0,000 6,701E-03 0,01685144 ! adrenoceptor activity GO:0004935 11 9 0,000 6,701E-03 0,01683958 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 9 9 0,000 6,701E-03 0,01682774 ! positive regulation of leukocyte migration GO:0002687 9 9 0,000 6,701E-03 0,01681591 ! purine base metabolic process GO:0006144 11 9 0,000 6,701E-03 0,0168041 ! mRNA 3'-UTR binding GO:0003730 9 9 0,000 6,701E-03 0,01679231 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 9 9 0,000 6,701E-03 0,01678054 ! receptor inhibitor activity GO:0030547 9 9 0,000 6,701E-03 0,01676878 GO:0048019|receptor antagonist activity, ! negative regulation of BMP signaling pathway GO:0030514 9 9 0,000 6,701E-03 0,01675703 ! ionotropic glutamate receptor complex GO:0008328 11 9 0,000 6,701E-03 0,01674531 ! transforming growth factor beta receptor binding GO:0005160 9 9 0,000 6,701E-03 0,0167336 ! palmitoyltransferase activity GO:0016409 9 9 0,000 6,701E-03 0,0167219 ! arylsulfatase activity GO:0004065 9 9 0,000 6,701E-03 0,01671023 ! phospholipase inhibitor activity GO:0004859 9 9 0,000 6,701E-03 0,01669857 ! behavioral response to nicotine GO:0035095 9 9 0,000 6,701E-03 0,01668692 ! adenylate kinase activity GO:0004017 10 9 0,000 6,701E-03 0,01667529 ! alcohol dehydrogenase (NAD) activity GO:0004022 9 9 0,000 6,701E-03 0,01666368 ! mitochondrion localization GO:0051646 9 9 0,000 6,701E-03 0,01665208 ! localization within membrane GO:0051668 9 9 0,000 6,701E-03 0,0166405 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 10 0,000 7,443E-03 0,01847033 ! lipid particle GO:0005811 10 10 0,000 7,443E-03 0,01845751 ! myotube differentiation GO:0014902 10 10 0,000 7,443E-03 0,0184447 ! generation of neurons in the forebrain GO:0021872 11 10 0,000 7,443E-03 0,01843191 ! regulation of cellular amine metabolic process GO:0033238 10 10 0,000 7,443E-03 0,01841913 ! synapsis GO:0007129 10 10 0,000 7,443E-03 0,01840638 GO:0070192|chromosome organization involved in meiosis, ! filopodium assembly GO:0046847 12 10 0,000 7,443E-03 0,01839364 ! UTP metabolic process GO:0046051 10 10 0,000 7,443E-03 0,01838092 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 10 10 0,000 7,443E-03 0,01836822 ! COPI coating of Golgi vesicle GO:0048205 10 10 0,000 7,443E-03 0,01835553 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 10 10 0,000 7,443E-03 0,01834286 ! platelet alpha granule membrane GO:0031092 11 10 0,000 7,443E-03 0,01833021 ! macromolecule transmembrane transporter activity GO:0022884 10 10 0,000 7,443E-03 0,01831758 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! lipoprotein receptor binding GO:0070325 10 10 0,000 7,443E-03 0,01830496 GO:0050750|low-density lipoprotein receptor binding, ! thyroid hormone receptor coactivator activity GO:0030375 10 10 0,000 7,443E-03 0,01829237 GO:0010861|thyroid hormone receptor activator activity, ! auditory receptor cell differentiation GO:0042491 11 10 0,000 7,443E-03 0,01827979 ! regulation of chemokine biosynthetic process GO:0045073 10 10 0,000 7,443E-03 0,01826722 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 10 10 0,000 7,443E-03 0,01825468 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 7,443E-03 0,01824215 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 10 10 0,000 7,443E-03 0,01822964 ! nucleotide-sugar metabolic process GO:0009225 11 10 0,000 7,443E-03 0,01821714 ! regulation of catecholamine secretion GO:0050433 10 10 0,000 7,443E-03 0,01820466 ! melanocyte differentiation GO:0030318 10 10 0,000 7,443E-03 0,0181922 GO:0050931|pigment cell differentiation, ! ER-Golgi intermediate compartment membrane GO:0033116 10 10 0,000 7,443E-03 0,01817976 ! deoxyribonucleotide catabolic process GO:0009264 10 10 0,000 7,443E-03 0,01816733 ! L-serine metabolic process GO:0006563 11 10 0,000 7,443E-03 0,01815492 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 10 10 0,000 7,443E-03 0,01814253 ! lipase inhibitor activity GO:0055102 10 10 0,000 7,443E-03 0,01813016 ! autophagic vacuole GO:0005776 11 10 0,000 7,443E-03 0,0181178 ! NAD metabolic process GO:0019674 10 10 0,000 7,443E-03 0,01810546 ! stereocilium GO:0032420 10 10 0,000 7,443E-03 0,01809313 GO:0032421|stereocilium bundle, ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 7,443E-03 0,01808082 ! regulation of sodium ion transport GO:0002028 10 10 0,000 7,443E-03 0,01806853 ! forebrain cell migration GO:0021885 10 10 0,000 7,443E-03 0,01805626 ! organelle subcompartment GO:0031984 11 10 0,000 7,443E-03 0,018044 ! chondrocyte differentiation GO:0002062 10 10 0,000 7,443E-03 0,01803176 ! negative regulation of ossification GO:0030279 10 10 0,000 7,443E-03 0,01801953 ! regulation of smoothened signaling pathway GO:0008589 10 10 0,000 7,443E-03 0,01800732 ! heparan sulfate proteoglycan metabolic process GO:0030201 10 10 0,000 7,443E-03 0,01799513 ! phosphatidylcholine biosynthetic process GO:0006656 12 10 0,000 7,443E-03 0,01798296 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 10 10 0,000 7,443E-03 0,0179708 ! protein homotetramerization GO:0051289 11 10 0,000 7,443E-03 0,01795865 ! oligodendrocyte development GO:0014003 10 10 0,000 7,443E-03 0,01794653 ! positive regulation of phagocytosis GO:0050766 10 10 0,000 7,443E-03 0,01793442 ! response to dsRNA GO:0043331 10 10 0,000 7,443E-03 0,01792233 ! mismatch repair complex binding GO:0032404 11 10 0,000 7,443E-03 0,01791025 ! snRNA metabolic process GO:0016073 10 10 0,000 7,443E-03 0,01789819 GO:0016180|snRNA processing, ! cranial nerve development GO:0021545 10 10 0,000 7,443E-03 0,01788614 ! fucose catabolic process GO:0019317 11 10 0,000 7,443E-03 0,01787411 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 10 10 0,000 7,443E-03 0,0178621 ! retinal binding GO:0016918 10 10 0,000 7,443E-03 0,01785011 ! leukocyte activation during immune response GO:0002366 10 10 0,000 7,443E-03 0,01783813 GO:0002263|cell activation during immune response, ! cerebellum morphogenesis GO:0021587 11 10 0,000 7,443E-03 0,01782616 GO:0021696|cerebellar cortex morphogenesis, ! photoreceptor outer segment GO:0001750 10 10 0,000 7,443E-03 0,01781421 ! negative regulation of MAPKKK cascade GO:0043409 10 10 0,000 7,443E-03 0,01780228 ! regulation of T-helper 2 type immune response GO:0002828 10 10 0,000 7,443E-03 0,01779037 ! ribonuclease P activity GO:0004526 10 10 0,000 7,443E-03 0,01777847 ! midbrain development GO:0030901 10 10 0,000 7,443E-03 0,01776658 ! musculoskeletal movement GO:0050881 10 10 0,000 7,443E-03 0,01775472 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 10 10 0,000 7,443E-03 0,01774286 ! regulation of T-helper cell differentiation GO:0045622 10 10 0,000 7,443E-03 0,01773103 ! fatty-acid ligase activity GO:0015645 10 10 0,000 7,443E-03 0,01771921 GO:0004467|long-chain-fatty-acid-CoA ligase activity, ! regulation of mRNA stability GO:0043488 10 10 0,000 7,443E-03 0,0177074 ! quaternary ammonium group transport GO:0015697 10 10 0,000 7,443E-03 0,01769561 ! regulation of RNA splicing GO:0043484 10 10 0,000 7,443E-03 0,01768384 ! embryonic gut development GO:0048566 10 10 0,000 7,443E-03 0,01767208 ! positive regulation of amine transport GO:0051954 10 10 0,000 7,443E-03 0,01766034 ! defense response to Gram-positive bacterium GO:0050830 10 10 0,000 7,443E-03 0,01764861 ! mRNA 3'-end processing GO:0031124 10 10 0,000 7,443E-03 0,0176369 ! lysogeny GO:0030069 10 10 0,000 7,443E-03 0,0176252 GO:0019047|provirus integration, ! lamellipodium assembly GO:0030032 11 10 0,000 7,443E-03 0,01761352 ! establishment of cell polarity GO:0030010 10 10 0,000 7,443E-03 0,01760186 ! regulation of synapse organization GO:0050807 10 10 0,000 7,443E-03 0,01759021 ! cell wall macromolecule metabolic process GO:0044036 11 10 0,000 7,443E-03 0,01757858 ! acyl-CoA binding GO:0000062 10 10 0,000 7,443E-03 0,01756696 ! negative regulation of muscle development GO:0048635 11 10 0,000 7,443E-03 0,01755536 GO:0045843|negative regulation of striated muscle development, ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 7,443E-03 0,01754377 ! GDP binding GO:0019003 10 10 0,000 7,443E-03 0,0175322 ! photoreceptor activity GO:0009881 10 10 0,000 7,443E-03 0,01752064 ! somatic diversification of immune receptors via somatic mutation GO:0002566 10 10 0,000 7,443E-03 0,0175091 GO:0016446|somatic hypermutation of immunoglobulin genes, ! cortical cytoskeleton organization GO:0030865 10 10 0,000 7,443E-03 0,01749757 ! nitric-oxide synthase binding GO:0050998 11 10 0,000 7,443E-03 0,01748606 ! nuclear chromosome, telomeric region GO:0000784 10 10 0,000 7,443E-03 0,01747456 ! nucleotidase activity GO:0008252 10 10 0,000 7,443E-03 0,01746308 ! detection of mechanical stimulus GO:0050982 10 10 0,000 7,443E-03 0,01745161 ! protein complex disassembly GO:0043241 11 10 0,000 7,443E-03 0,01744016 GO:0043624|cellular protein complex disassembly, ! androgen metabolic process GO:0008209 10 10 0,000 7,443E-03 0,01742873 ! lateral plasma membrane GO:0016328 10 10 0,000 7,443E-03 0,01741731 ! estrogen metabolic process GO:0008210 10 10 0,000 7,443E-03 0,0174059 ! nucleocytoplasmic transporter activity GO:0005487 10 10 0,000 7,443E-03 0,01739451 ! retinol dehydrogenase activity GO:0004745 10 10 0,000 7,443E-03 0,01738313 ! negative regulation of cell-matrix adhesion GO:0001953 12 10 0,000 7,443E-03 0,01737177 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 11 10 0,000 7,443E-03 0,01736042 ! interleukin-1 binding GO:0019966 10 10 0,000 7,443E-03 0,01734909 ! endothelial cell differentiation GO:0045446 10 10 0,000 7,443E-03 0,01733777 ! cullin-RING ubiquitin ligase complex GO:0031461 10 10 0,000 7,443E-03 0,01732647 ! acid phosphatase activity GO:0003993 10 10 0,000 7,443E-03 0,01731518 ! sodium:potassium-exchanging ATPase activity GO:0005391 11 10 0,000 7,443E-03 0,01730391 ! calcium-transporting ATPase activity GO:0005388 12 10 0,000 7,443E-03 0,01729265 ! telomeric DNA binding GO:0042162 11 10 0,000 7,443E-03 0,01728141 ! regulation of intracellular pH GO:0051453 10 10 0,000 7,443E-03 0,01727018 ! lipid digestion GO:0044241 10 10 0,000 7,443E-03 0,01725897 ! multicellular organism growth GO:0035264 10 10 0,000 7,443E-03 0,01724777 ! receptor clustering GO:0043113 10 10 0,000 7,443E-03 0,01723658 ! L-glutamate transmembrane transporter activity GO:0005313 10 10 0,000 7,443E-03 0,01722541 GO:0015172|acidic amino acid transmembrane transporter activity, ! brush border membrane GO:0031526 11 10 0,000 7,443E-03 0,01721425 ! adult heart development GO:0007512 12 10 0,000 7,443E-03 0,01720311 ! actin cytoskeleton reorganization GO:0031532 12 10 0,000 7,443E-03 0,01719198 ! signalosome GO:0008180 10 10 0,000 7,443E-03 0,01718087 ! prefoldin complex GO:0016272 10 10 0,000 7,443E-03 0,01716977 ! neuromuscular junction GO:0031594 10 10 0,000 7,443E-03 0,01715869 ! regulation of bone resorption GO:0045124 11 10 0,000 7,443E-03 0,01714762 ! positive regulation of peptide secretion GO:0002793 10 10 0,000 7,443E-03 0,01713656 ! alpha-beta T cell differentiation GO:0046632 11 10 0,000 7,443E-03 0,01712552 ! negative regulation of myeloid leukocyte differentiation GO:0002762 10 10 0,000 7,443E-03 0,01711449 ! positive regulation of T cell mediated immunity GO:0002711 14 10 0,000 7,443E-03 0,01710348 ! taste receptor activity GO:0008527 10 10 0,000 7,443E-03 0,01709248 ! Ran GTPase binding GO:0008536 10 10 0,000 7,443E-03 0,0170815 ! endocytic vesicle membrane GO:0030666 10 10 0,000 7,443E-03 0,01707053 ! regulation of interleukin-12 production GO:0032655 10 10 0,000 7,443E-03 0,01705957 ! ribosome assembly GO:0042255 10 10 0,000 7,443E-03 0,01704863 ! DNA methylation GO:0006306 12 10 0,000 7,443E-03 0,0170377 GO:0006305|DNA alkylation, ! protein-hormone receptor activity GO:0016500 10 10 0,000 7,443E-03 0,01702678 ! bile acid transmembrane transporter activity GO:0015125 10 10 0,000 7,443E-03 0,01701588 ! proteasome accessory complex GO:0022624 11 10 0,000 7,443E-03 0,017005 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 13 10 0,000 7,443E-03 0,01699412 ! prostaglandin receptor activity GO:0004955 11 10 0,000 7,443E-03 0,01698326 ! regulation of isotype switching GO:0045191 14 10 0,000 7,443E-03 0,01697242 ! peptide transporter activity GO:0015197 10 10 0,000 7,443E-03 0,01696159 ! regulation of leukocyte migration GO:0002685 10 10 0,000 7,443E-03 0,01695077 ! retinoid-X receptor activity GO:0004886 10 10 0,000 7,443E-03 0,01693997 ! GTPase inhibitor activity GO:0005095 10 10 0,000 7,443E-03 0,01692918 ! pattern recognition receptor activity GO:0008329 10 10 0,000 7,443E-03 0,0169184 ! gamma-tubulin complex GO:0000930 12 10 0,000 7,443E-03 0,01690764 ! germ cell migration GO:0008354 10 10 0,000 7,443E-03 0,01689689 ! regulation of organic acid transport GO:0032890 10 10 0,000 7,443E-03 0,01688616 ! negative regulation of mast cell proliferation GO:0070667 10 10 0,000 7,443E-03 0,01687543 GO:0042130|negative regulation of T cell proliferation, ! cardiac cell differentiation GO:0035051 11 10 0,000 7,443E-03 0,01686473 ! amiloride-sensitive sodium channel activity GO:0015280 10 10 0,000 7,443E-03 0,01685403 ! sterol transporter activity GO:0015248 10 10 0,000 7,443E-03 0,01684335 ! regulation of embryonic development GO:0045995 11 10 0,000 7,443E-03 0,01683268 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 11 11 0,000 8,184E-03 0,01849796 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 11 0,000 8,184E-03 0,01848626 ! negative regulation of blood pressure GO:0045776 11 11 0,000 8,184E-03 0,01847457 ! RNA cap binding GO:0000339 12 11 0,000 8,184E-03 0,0184629 ! CTP metabolic process GO:0046036 12 11 0,000 8,184E-03 0,01845125 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 11 0,000 8,184E-03 0,0184396 ! response to pain GO:0048265 11 11 0,000 8,184E-03 0,01842798 ! axonemal dynein complex GO:0005858 11 11 0,000 8,184E-03 0,01841637 ! eukaryotic translation initiation factor 3 complex GO:0005852 11 11 0,000 8,184E-03 0,01840477 ! dopamine receptor signaling pathway GO:0007212 13 11 0,000 8,184E-03 0,01839319 ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 11 0,000 8,184E-03 0,01838162 ! endocrine pancreas development GO:0031018 11 11 0,000 8,184E-03 0,01837006 ! regulation of interferon-gamma biosynthetic process GO:0045072 12 11 0,000 8,184E-03 0,01835853 ! regulation of exit from mitosis GO:0007096 11 11 0,000 8,184E-03 0,018347 ! chylomicron GO:0042627 11 11 0,000 8,184E-03 0,01833549 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 11 11 0,000 8,184E-03 0,018324 ! glycolipid biosynthetic process GO:0009247 11 11 0,000 8,184E-03 0,01831251 ! transforming growth factor beta binding GO:0050431 11 11 0,000 8,184E-03 0,01830105 ! glutamate metabolic process GO:0006536 12 11 0,000 8,184E-03 0,0182896 ! ribonucleotide catabolic process GO:0009261 11 11 0,000 8,184E-03 0,01827816 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 8,184E-03 0,01826673 ! vascular endothelial growth factor receptor activity GO:0005021 11 11 0,000 8,184E-03 0,01825532 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 11 11 0,000 8,184E-03 0,01824393 GO:0045125|bioactive lipid receptor activity, ! Rac GTPase binding GO:0048365 11 11 0,000 8,184E-03 0,01823255 ! epithelial cell development GO:0002064 11 11 0,000 8,184E-03 0,01822118 ! filamentous actin GO:0031941 11 11 0,000 8,184E-03 0,01820983 ! temperature homeostasis GO:0001659 11 11 0,000 8,184E-03 0,01819849 ! structural constituent of epidermis GO:0030280 13 11 0,000 8,184E-03 0,01818716 ! protein targeting to peroxisome GO:0006625 11 11 0,000 8,184E-03 0,01817585 ! spectrin GO:0008091 11 11 0,000 8,184E-03 0,01816456 ! cytoskeletal adaptor activity GO:0008093 14 11 0,000 8,184E-03 0,01815328 ! negative regulation of axonogenesis GO:0050771 13 11 0,000 8,184E-03 0,01814201 ! regulation of phagocytosis GO:0050764 11 11 0,000 8,184E-03 0,01813075 ! nucleoside triphosphate catabolic process GO:0009143 11 11 0,000 8,184E-03 0,01811951 ! synaptic vesicle exocytosis GO:0016079 12 11 0,000 8,184E-03 0,01810829 ! regulation of B cell differentiation GO:0045577 15 11 0,000 8,184E-03 0,01809707 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 11 11 0,000 8,184E-03 0,01808587 ! basal lamina GO:0005605 12 11 0,000 8,184E-03 0,01807469 ! gastrulation with mouth forming second GO:0001702 12 11 0,000 8,184E-03 0,01806352 ! spinal cord motor neuron differentiation GO:0021522 11 11 0,000 8,184E-03 0,01805236 ! hindbrain morphogenesis GO:0021575 13 11 0,000 8,184E-03 0,01804122 ! regulation of hormone metabolic process GO:0032350 12 11 0,000 8,184E-03 0,01803009 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 11 0,000 8,184E-03 0,01801897 GO:0050706|regulation of interleukin-1 beta secretion, ! COPI vesicle coat GO:0030126 11 11 0,000 8,184E-03 0,01800787 GO:0030663|COPI coated vesicle membrane, ! clathrin coat of trans-Golgi network vesicle GO:0030130 14 11 0,000 8,184E-03 0,01799678 ! tRNA-specific ribonuclease activity GO:0004549 11 11 0,000 8,184E-03 0,01798571 ! cofactor transporter activity GO:0051184 11 11 0,000 8,184E-03 0,01797465 ! cobalt ion binding GO:0050897 11 11 0,000 8,184E-03 0,0179636 ! pseudouridine synthase activity GO:0009982 12 11 0,000 8,184E-03 0,01795256 ! aromatic amino acid family catabolic process GO:0009074 12 11 0,000 8,184E-03 0,01794154 ! serine family amino acid biosynthetic process GO:0009070 11 11 0,000 8,184E-03 0,01793054 ! histone deacetylase binding GO:0042826 11 11 0,000 8,184E-03 0,01791954 ! spleen development GO:0048536 12 11 0,000 8,184E-03 0,01790856 ! regulation of RNA stability GO:0043487 11 11 0,000 8,184E-03 0,0178976 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 12 11 0,000 8,184E-03 0,01788664 ! acid-thiol ligase activity GO:0016878 11 11 0,000 8,184E-03 0,0178757 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 11 11 0,000 8,184E-03 0,01786478 ! blastocyst formation GO:0001825 11 11 0,000 8,184E-03 0,01785386 ! cerebellar cortex development GO:0021695 12 11 0,000 8,184E-03 0,01784296 ! ADP binding GO:0043531 11 11 0,000 8,184E-03 0,01783208 ! folic acid binding GO:0005542 11 11 0,000 8,184E-03 0,0178212 ! FK506 binding GO:0005528 11 11 0,000 8,184E-03 0,01781034 GO:0005527|macrolide binding, ! defense response to fungus GO:0050832 11 11 0,000 8,184E-03 0,0177995 ! extracellular matrix binding GO:0050840 13 11 0,000 8,184E-03 0,01778866 ! microspike assembly GO:0030035 13 11 0,000 8,184E-03 0,01777784 ! cytoplasmic sequestering of protein GO:0051220 11 11 0,000 8,184E-03 0,01776704 ! regulation of synapse structure and activity GO:0050803 11 11 0,000 8,184E-03 0,01775624 ! organ formation GO:0048645 12 11 0,000 8,184E-03 0,01774546 ! embryonic hindlimb morphogenesis GO:0035116 11 11 0,000 8,184E-03 0,01773469 ! embryonic forelimb morphogenesis GO:0035115 11 11 0,000 8,184E-03 0,01772394 ! cellular copper ion homeostasis GO:0006878 12 11 0,000 8,184E-03 0,0177132 ! glycosaminoglycan catabolic process GO:0006027 11 11 0,000 8,184E-03 0,01770247 ! Golgi vesicle budding GO:0048194 11 11 0,000 8,184E-03 0,01769175 ! regulation of positive chemotaxis GO:0050926 11 11 0,000 8,184E-03 0,01768105 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 11 11 0,000 8,184E-03 0,01767036 ! ion channel inhibitor activity GO:0008200 13 11 0,000 8,184E-03 0,01765968 GO:0016248|channel inhibitor activity, ! positive regulation of transcription factor import into nucleus GO:0042993 12 11 0,000 8,184E-03 0,01764902 ! MAP kinase kinase activity GO:0004708 11 11 0,000 8,184E-03 0,01763837 GO:0004712|protein serine/threonine/tyrosine kinase activity, ! cation:amino acid symporter activity GO:0005416 11 11 0,000 8,184E-03 0,01762773 ! mannosyltransferase activity GO:0000030 11 11 0,000 8,184E-03 0,0176171 ! cAMP-dependent protein kinase activity GO:0004691 11 11 0,000 8,184E-03 0,01760649 ! FMN binding GO:0010181 11 11 0,000 8,184E-03 0,01759589 ! response to X-ray GO:0010165 12 11 0,000 8,184E-03 0,0175853 ! focal adhesion formation GO:0048041 13 11 0,000 8,184E-03 0,01757473 ! actin polymerization or depolymerization GO:0008154 13 11 0,000 8,184E-03 0,01756417 ! substrate-bound cell migration GO:0006929 11 11 0,000 8,184E-03 0,01755362 ! integrator complex GO:0032039 11 11 0,000 8,184E-03 0,01754308 ! UV protection GO:0009650 11 11 0,000 8,184E-03 0,01753256 ! L-glutamate transport GO:0015813 11 11 0,000 8,184E-03 0,01752205 GO:0015800|acidic amino acid transport, ! retinol binding GO:0019841 11 11 0,000 8,184E-03 0,01751155 ! regulation of organ growth GO:0046620 12 11 0,000 8,184E-03 0,01750106 ! regulation of cytokine production during immune response GO:0002718 11 11 0,000 8,184E-03 0,01749059 ! regulation of T cell mediated immunity GO:0002709 15 11 0,000 8,184E-03 0,01748013 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 11 11 0,000 8,184E-03 0,01746968 ! regulation of interleukin-8 production GO:0032677 12 11 0,000 8,184E-03 0,01745924 ! histone acetylation GO:0016573 11 11 0,000 8,184E-03 0,01744882 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 12 11 0,000 8,184E-03 0,01743841 ! delayed rectifier potassium channel activity GO:0005251 11 11 0,000 8,184E-03 0,01742801 ! organic cation transmembrane transporter activity GO:0015101 11 11 0,000 8,184E-03 0,01741762 ! chromatin silencing GO:0006342 11 11 0,000 8,184E-03 0,01740725 ! gland morphogenesis GO:0022612 12 11 0,000 8,184E-03 0,01739689 ! sulfate transmembrane transporter activity GO:0015116 11 11 0,000 8,184E-03 0,01738654 ! hexose transmembrane transporter activity GO:0015149 11 11 0,000 8,184E-03 0,0173762 ! icosanoid receptor activity GO:0004953 12 11 0,000 8,184E-03 0,01736588 GO:0004954|prostanoid receptor activity, ! non-G-protein coupled 7TM receptor activity GO:0004926 12 11 0,000 8,184E-03 0,01735557 ! negative regulation of neurological system process GO:0031645 12 11 0,000 8,184E-03 0,01734527 ! acid secretion GO:0046717 11 11 0,000 8,184E-03 0,01733498 ! nitric oxide mediated signal transduction GO:0007263 11 11 0,000 8,184E-03 0,0173247 ! thyroid hormone metabolic process GO:0042403 11 11 0,000 8,184E-03 0,01731444 ! quinone cofactor metabolic process GO:0042375 12 11 0,000 8,184E-03 0,01730419 ! insulin-like growth factor receptor binding GO:0005159 12 11 0,000 8,184E-03 0,01729395 ! midbody GO:0030496 11 11 0,000 8,184E-03 0,01728372 ! interferon-alpha/beta receptor binding GO:0005132 11 11 0,000 8,184E-03 0,01727351 ! cAMP-dependent protein kinase complex GO:0005952 11 11 0,000 8,184E-03 0,0172633 ! water channel activity GO:0015250 11 11 0,000 8,184E-03 0,01725311 ! response to nicotine GO:0035094 11 11 0,000 8,184E-03 0,01724293 ! response to cold GO:0009409 11 11 0,000 8,184E-03 0,01723277 ! adenylate cyclase activity GO:0004016 11 11 0,000 8,184E-03 0,01722261 ! 'de novo' protein folding GO:0006458 12 12 0,000 8,925E-03 0,01877087 ! centriole GO:0005814 12 12 0,000 8,925E-03 0,01875982 ! organellar large ribosomal subunit GO:0000315 13 12 0,000 8,925E-03 0,01874879 GO:0005762|mitochondrial large ribosomal subunit, ! cadmium ion binding GO:0046870 13 12 0,000 8,925E-03 0,01873777 ! folic acid and derivative biosynthetic process GO:0009396 12 12 0,000 8,925E-03 0,01872676 ! bone remodeling GO:0046849 12 12 0,000 8,925E-03 0,01871576 ! peroxisomal transport GO:0043574 12 12 0,000 8,925E-03 0,01870478 ! retina development in camera-type eye GO:0060041 13 12 0,000 8,925E-03 0,01869381 ! hair follicle morphogenesis GO:0031069 12 12 0,000 8,925E-03 0,01868285 ! voltage-gated sodium channel complex GO:0001518 13 12 0,000 8,925E-03 0,0186719 GO:0034706|sodium channel complex, ! regulation of excitatory postsynaptic membrane potential GO:0060079 14 12 0,000 8,925E-03 0,01866097 ! hippocampus development GO:0021766 12 12 0,000 8,925E-03 0,01865005 ! negative regulation of lipid metabolic process GO:0045833 13 12 0,000 8,925E-03 0,01863915 ! T cell selection GO:0045058 16 12 0,000 8,925E-03 0,01862825 ! cation:cation antiporter activity GO:0015491 12 12 0,000 8,925E-03 0,01861737 ! induction of apoptosis via death domain receptors GO:0008625 12 12 0,000 8,925E-03 0,0186065 ! T-tubule GO:0030315 13 12 0,000 8,925E-03 0,01859565 ! methionine metabolic process GO:0006555 13 12 0,000 8,925E-03 0,0185848 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 14 12 0,000 8,925E-03 0,01857397 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! peptide antigen binding GO:0042605 12 12 0,000 8,925E-03 0,01856316 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 8,925E-03 0,01855235 ! cell-cell junction assembly GO:0007043 12 12 0,000 8,925E-03 0,01854156 ! mitotic spindle organization GO:0007052 12 12 0,000 8,925E-03 0,01853078 ! fear response GO:0042596 12 12 0,000 8,925E-03 0,01852001 ! negative regulation of mitotic cell cycle GO:0045930 13 12 0,000 8,925E-03 0,01850926 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 8,925E-03 0,01849851 ! copper ion homeostasis GO:0055070 13 12 0,000 8,925E-03 0,01848778 ! lipoprotein receptor activity GO:0030228 12 12 0,000 8,925E-03 0,01847707 ! axon cargo transport GO:0008088 12 12 0,000 8,925E-03 0,01846636 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 13 12 0,000 8,925E-03 0,01845567 ! transcription elongation factor complex GO:0008023 13 12 0,000 8,925E-03 0,01844499 ! nuclear outer membrane GO:0005640 12 12 0,000 8,925E-03 0,01843432 ! beta-tubulin binding GO:0048487 12 12 0,000 8,925E-03 0,01842366 ! autonomic nervous system development GO:0048483 12 12 0,000 8,925E-03 0,01841302 ! positive regulation of interleukin-1 secretion GO:0050716 12 12 0,000 8,925E-03 0,01840239 GO:0050704|regulation of interleukin-1 secretion, ! exoribonuclease activity GO:0004532 12 12 0,000 8,925E-03 0,01839177 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! cofactor transport GO:0051181 12 12 0,000 8,925E-03 0,01838116 ! regulation of epidermis development GO:0045682 12 12 0,000 8,925E-03 0,01837057 ! protein-chromophore linkage GO:0018298 12 12 0,000 8,925E-03 0,01835999 ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 12 12 0,000 8,925E-03 0,01834942 ! cell killing GO:0001906 12 12 0,000 8,925E-03 0,01833886 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 12 0,000 8,925E-03 0,01832831 ! regulation of fatty acid oxidation GO:0046320 13 12 0,000 8,925E-03 0,01831778 ! detection of bacterium GO:0016045 13 12 0,000 8,925E-03 0,01830726 ! positive regulation of neuron apoptosis GO:0043525 12 12 0,000 8,925E-03 0,01829675 ! dystrophin-associated glycoprotein complex GO:0016010 14 12 0,000 8,925E-03 0,01828625 ! internal side of plasma membrane GO:0009898 14 12 0,000 8,925E-03 0,01827577 ! RNA 3'-end processing GO:0031123 12 12 0,000 8,925E-03 0,01826529 ! developmental induction GO:0031128 13 12 0,000 8,925E-03 0,01825483 GO:0045168|cell-cell signaling involved in cell fate specification, ! fibrillar collagen GO:0005583 13 12 0,000 8,925E-03 0,01824438 ! positive regulation of calcium-mediated signaling GO:0050850 14 12 0,000 8,925E-03 0,01823395 ! inner ear receptor cell differentiation GO:0060113 13 12 0,000 8,925E-03 0,01822352 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 8,925E-03 0,01821311 ! very-long-chain fatty acid metabolic process GO:0000038 12 12 0,000 8,925E-03 0,01820271 ! negative regulation of cell projection organization GO:0031345 14 12 0,000 8,925E-03 0,01819232 ! thyroid gland development GO:0030878 12 12 0,000 8,925E-03 0,01818194 ! non-recombinational repair GO:0000726 12 12 0,000 8,925E-03 0,01817157 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 12 12 0,000 8,925E-03 0,01816122 ! lipid localization GO:0010876 12 12 0,000 8,925E-03 0,01815088 GO:0019915|lipid storage, ! regulation of glycolysis GO:0006110 12 12 0,000 8,925E-03 0,01814055 ! response to cAMP GO:0051591 12 12 0,000 8,925E-03 0,01813023 ! negative regulation of transcription factor import into nucleus GO:0042992 12 12 0,000 8,925E-03 0,01811992 ! T cell proliferation GO:0042098 17 12 0,000 8,925E-03 0,01810962 ! negative regulation of protein amino acid phosphorylation GO:0001933 16 12 0,000 8,925E-03 0,01809934 ! receptor signaling protein tyrosine kinase activity GO:0004716 13 12 0,000 8,925E-03 0,01808907 ! two-component signal transduction system (phosphorelay) GO:0000160 13 12 0,000 8,925E-03 0,01807881 ! peptide or protein amino-terminal blocking GO:0018409 13 12 0,000 8,925E-03 0,01806856 ! drug transport GO:0015893 12 12 0,000 8,925E-03 0,01805832 ! GTP-dependent protein binding GO:0030742 12 12 0,000 8,925E-03 0,0180481 ! regulation of interleukin-6 biosynthetic process GO:0045408 12 12 0,000 8,925E-03 0,01803788 ! T cell receptor complex GO:0042101 12 12 0,000 8,925E-03 0,01802768 ! membrane protein proteolysis GO:0033619 13 12 0,000 8,925E-03 0,01801749 GO:0006509|membrane protein ectodomain proteolysis, ! protein disulfide oxidoreductase activity GO:0015035 12 12 0,000 8,925E-03 0,01800731 ! histone acetyltransferase complex GO:0000123 13 12 0,000 8,925E-03 0,01799714 ! dendritic spine GO:0043197 12 12 0,000 8,925E-03 0,01798699 ! ATP-binding cassette (ABC) transporter complex GO:0043190 12 12 0,000 8,925E-03 0,01797684 ! alpha-beta T cell activation GO:0046631 13 12 0,000 8,925E-03 0,01796671 ! organic anion transmembrane transporter activity GO:0008514 13 12 0,000 8,925E-03 0,01795659 ! vasoconstriction GO:0042310 13 12 0,000 8,925E-03 0,01794648 ! DNA unwinding during replication GO:0006268 12 12 0,000 8,925E-03 0,01793638 ! cellular amino acid derivative catabolic process GO:0042219 16 12 0,000 8,925E-03 0,01792629 ! mRNA splice site selection GO:0006376 13 12 0,000 8,925E-03 0,01791621 ! phosphate transmembrane transporter activity GO:0015114 13 12 0,000 8,925E-03 0,01790615 ! trans-Golgi network transport vesicle membrane GO:0012510 15 12 0,000 8,925E-03 0,01789609 ! ubiquitin protein ligase binding GO:0031625 12 12 0,000 8,925E-03 0,01788605 ! monosaccharide transmembrane transporter activity GO:0015145 12 12 0,000 8,925E-03 0,01787602 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 12 12 0,000 8,925E-03 0,017866 ! hexosaminidase activity GO:0015929 12 12 0,000 8,925E-03 0,01785599 ! diacylglycerol kinase activity GO:0004143 13 12 0,000 8,925E-03 0,01784599 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 8,925E-03 0,017836 ! activation of NF-kappaB-inducing kinase activity GO:0007250 12 12 0,000 8,925E-03 0,01782603 ! protein kinase C binding GO:0005080 13 12 0,000 8,925E-03 0,01781606 ! catecholamine biosynthetic process GO:0042423 13 12 0,000 8,925E-03 0,01780611 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 15 12 0,000 8,925E-03 0,01779617 ! establishment or maintenance of apical/basal cell polarity GO:0035088 12 12 0,000 8,925E-03 0,01778624 ! L-fucose metabolic process GO:0042354 14 12 0,000 8,925E-03 0,01777632 ! acylglycerol O-acyltransferase activity GO:0016411 12 12 0,000 8,925E-03 0,01776641 ! C-acyltransferase activity GO:0016408 12 12 0,000 8,925E-03 0,01775651 ! steroid hydroxylase activity GO:0008395 12 12 0,000 8,925E-03 0,01774663 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 8,925E-03 0,01773675 ! calcium-activated potassium channel activity GO:0015269 14 12 0,000 8,925E-03 0,01772689 ! SWI/SNF-type complex GO:0070603 13 12 0,000 8,925E-03 0,01771703 GO:0016514|SWI/SNF complex, ! cilium part GO:0044441 12 12 0,000 8,925E-03 0,01770719 ! positive regulation of translation GO:0045727 13 13 0,000 9,666E-03 0,01916563 ! ER-associated protein catabolic process GO:0030433 13 13 0,000 9,666E-03 0,019155 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 9,666E-03 0,01914438 ! superoxide anion generation GO:0042554 13 13 0,000 9,666E-03 0,01913376 ! pteridine and derivative biosynthetic process GO:0042559 14 13 0,000 9,666E-03 0,01912316 ! cis-Golgi network GO:0005801 14 13 0,000 9,666E-03 0,01911257 ! regulation of S phase GO:0033261 17 13 0,000 9,666E-03 0,019102 ! regulation of chemokine production GO:0032642 13 13 0,000 9,666E-03 0,01909143 ! phospholipid catabolic process GO:0009395 14 13 0,000 9,666E-03 0,01908088 ! endothelial cell migration GO:0043542 13 13 0,000 9,666E-03 0,01907034 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 13 13 0,000 9,666E-03 0,01905981 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 9,666E-03 0,01904929 ! cartilage condensation GO:0001502 14 13 0,000 9,666E-03 0,01903878 ! organelle fusion GO:0048284 14 13 0,000 9,666E-03 0,01902828 ! positive regulation of lipid metabolic process GO:0045834 13 13 0,000 9,666E-03 0,0190178 ! pseudouridine synthesis GO:0001522 14 13 0,000 9,666E-03 0,01900733 ! negative regulation of gene expression, epigenetic GO:0045814 13 13 0,000 9,666E-03 0,01899687 ! regulation of interleukin-2 biosynthetic process GO:0045076 13 13 0,000 9,666E-03 0,01898642 ! negative regulation of proteolysis GO:0045861 13 13 0,000 9,666E-03 0,01897598 ! regulation of mRNA processing GO:0050684 13 13 0,000 9,666E-03 0,01896555 ! arginine metabolic process GO:0006525 13 13 0,000 9,666E-03 0,01895514 ! WW domain binding GO:0050699 14 13 0,000 9,666E-03 0,01894474 ! cholesterol binding GO:0015485 13 13 0,000 9,666E-03 0,01893434 ! negative regulation of microtubule depolymerization GO:0007026 15 13 0,000 9,666E-03 0,01892396 GO:0031114|regulation of microtubule depolymerization, ! Golgi organization GO:0007030 16 13 0,000 9,666E-03 0,01891359 ! negative regulation of endothelial cell migration GO:0010596 13 13 0,000 9,666E-03 0,01890324 ! integral to peroxisomal membrane GO:0005779 13 13 0,000 9,666E-03 0,01889289 GO:0031231|intrinsic to peroxisomal membrane, ! integral to membrane of membrane fraction GO:0000299 14 13 0,000 9,666E-03 0,01888255 ! regulation of heart rate GO:0002027 14 13 0,000 9,666E-03 0,01887223 ! positive regulation of carbohydrate metabolic process GO:0045913 14 13 0,000 9,666E-03 0,01886192 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 14 13 0,000 9,666E-03 0,01885162 ! negative regulation of immune response GO:0050777 17 13 0,000 9,666E-03 0,01884133 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 13 0,000 9,666E-03 0,01883105 ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 9,666E-03 0,01882078 ! response to estradiol stimulus GO:0032355 14 13 0,000 9,666E-03 0,01881052 ! anaphase-promoting complex GO:0005680 13 13 0,000 9,666E-03 0,01880028 ! nucleotide diphosphatase activity GO:0004551 13 13 0,000 9,666E-03 0,01879004 ! NADP metabolic process GO:0006739 13 13 0,000 9,666E-03 0,01877982 ! regulation of erythrocyte differentiation GO:0045646 13 13 0,000 9,666E-03 0,01876961 ! intestinal absorption GO:0050892 13 13 0,000 9,666E-03 0,01875941 ! eukaryotic cell surface binding GO:0043499 14 13 0,000 9,666E-03 0,01874922 ! digestive tract morphogenesis GO:0048546 13 13 0,000 9,666E-03 0,01873904 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 14 13 0,000 9,666E-03 0,01872887 ! regulation of cellular carbohydrate catabolic process GO:0043471 14 13 0,000 9,666E-03 0,01871871 GO:0043470|regulation of carbohydrate catabolic process, ! tropomyosin binding GO:0005523 13 13 0,000 9,666E-03 0,01870857 ! carbon-sulfur lyase activity GO:0016846 13 13 0,000 9,666E-03 0,01869843 ! embryonic placenta development GO:0001892 13 13 0,000 9,666E-03 0,01868831 ! positive regulation of protein polymerization GO:0032273 13 13 0,000 9,666E-03 0,0186782 ! insulin secretion GO:0030073 13 13 0,000 9,666E-03 0,0186681 ! positive regulation of cellular catabolic process GO:0031331 14 13 0,000 9,666E-03 0,018658 ! G1 phase of mitotic cell cycle GO:0000080 13 13 0,000 9,666E-03 0,01864792 ! replisome GO:0030894 14 13 0,000 9,666E-03 0,01863786 GO:0043601|nuclear replisome, ! regulation of nitric-oxide synthase activity GO:0050999 13 13 0,000 9,666E-03 0,0186278 ! double-strand break repair via homologous recombination GO:0000724 13 13 0,000 9,666E-03 0,01861775 GO:0000725|recombinational repair, ! copper ion transport GO:0006825 13 13 0,000 9,666E-03 0,01860771 ! regulation of cell-cell adhesion GO:0022407 13 13 0,000 9,666E-03 0,01859769 ! forelimb morphogenesis GO:0035136 13 13 0,000 9,666E-03 0,01858767 ! mating GO:0007618 13 13 0,000 9,666E-03 0,01857767 ! phosphatidylinositol phosphate kinase activity GO:0016307 14 13 0,000 9,666E-03 0,01856768 ! MAP kinase activity GO:0004707 14 13 0,000 9,666E-03 0,01855769 ! cytokine biosynthetic process GO:0042089 13 13 0,000 9,666E-03 0,01854772 ! ventral spinal cord development GO:0021517 13 13 0,000 9,666E-03 0,01853776 ! prenyltransferase activity GO:0004659 14 13 0,000 9,666E-03 0,01852781 ! platelet-derived growth factor receptor signaling pathway GO:0048008 15 13 0,000 9,666E-03 0,01851787 ! regulation of skeletal muscle fiber development GO:0048742 13 13 0,000 9,666E-03 0,01850794 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 15 13 0,000 9,666E-03 0,01849802 ! protein kinase C activity GO:0004697 15 13 0,000 9,666E-03 0,01848811 ! oligodendrocyte differentiation GO:0048709 13 13 0,000 9,666E-03 0,01847822 ! water transporter activity GO:0005372 13 13 0,000 9,666E-03 0,01846833 ! exocrine system development GO:0035272 14 13 0,000 9,666E-03 0,01845845 ! dicarboxylic acid transmembrane transporter activity GO:0005310 13 13 0,000 9,666E-03 0,01844859 ! monoamine transport GO:0015844 13 13 0,000 9,666E-03 0,01843873 ! CoA hydrolase activity GO:0016289 13 13 0,000 9,666E-03 0,01842889 ! embryo implantation GO:0007566 13 13 0,000 9,666E-03 0,01841905 ! G1/S transition checkpoint GO:0031575 13 13 0,000 9,666E-03 0,01840923 ! positive regulation of alpha-beta T cell differentiation GO:0046638 13 13 0,000 9,666E-03 0,01839942 ! immunoglobulin binding GO:0019865 13 13 0,000 9,666E-03 0,01838962 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 9,666E-03 0,01837982 ! anchored to plasma membrane GO:0046658 14 13 0,000 9,666E-03 0,01837004 ! MHC class I protein binding GO:0042288 13 13 0,000 9,666E-03 0,01836027 ! histone deacetylation GO:0016575 13 13 0,000 9,666E-03 0,01835051 ! calcium channel regulator activity GO:0005246 14 13 0,000 9,666E-03 0,01834076 ! neuroblast proliferation GO:0007405 13 13 0,000 9,666E-03 0,01833102 ! peptide biosynthetic process GO:0043043 14 13 0,000 9,666E-03 0,01832129 ! response to gamma radiation GO:0010332 13 13 0,000 9,666E-03 0,01831157 ! sarcomere organization GO:0045214 13 13 0,000 9,666E-03 0,01830186 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 15 13 0,000 9,666E-03 0,01829216 ! cAMP binding GO:0030552 13 13 0,000 9,666E-03 0,01828247 ! fucosyltransferase activity GO:0008417 14 13 0,000 9,666E-03 0,01827279 ! cilium assembly GO:0042384 13 13 0,000 9,666E-03 0,01826313 ! negative regulation of leukocyte proliferation GO:0070664 13 13 0,000 9,666E-03 0,01825347 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! bacterial binding GO:0008367 13 13 0,000 9,666E-03 0,01824382 ! regulation of NF-kappaB import into nucleus GO:0042345 13 13 0,000 9,666E-03 0,01823418 ! acrosome reaction GO:0007340 13 13 0,000 9,666E-03 0,01822456 ! microtubule-based flagellum GO:0009434 13 13 0,000 9,666E-03 0,01821494 ! nucleolar part GO:0044452 13 13 0,000 9,666E-03 0,01820533 ! axoneme part GO:0044447 13 13 0,000 9,666E-03 0,01819573 ! tRNA modification GO:0006400 14 14 0,000 0,01040602 0,01957844 ! positive regulation of blood pressure GO:0045777 15 14 0,000 0,01040602 0,01956813 ! transferase activity, transferring amino-acyl groups GO:0016755 14 14 0,000 0,01040602 0,01955783 ! negative regulation of bone remodeling GO:0046851 14 14 0,000 0,01040602 0,01954754 ! 2'-deoxyribonucleotide metabolic process GO:0009394 15 14 0,000 0,01040602 0,01953727 GO:0019692|deoxyribose phosphate metabolic process, ! transcription from RNA polymerase III promoter GO:0006383 14 14 0,000 0,01040602 0,019527 ! guanylate kinase activity GO:0004385 16 14 0,000 0,01040602 0,01951674 ! striated muscle thin filament GO:0005865 15 14 0,000 0,01040602 0,0195065 ! patterning of blood vessels GO:0001569 14 14 0,000 0,01040602 0,01949626 ! mechanoreceptor differentiation GO:0042490 15 14 0,000 0,01040602 0,01948604 ! palate development GO:0060021 15 14 0,000 0,01040602 0,01947583 ! centrosome cycle GO:0007098 14 14 0,000 0,01040602 0,01946563 ! regulation of defense response to virus GO:0050688 14 14 0,000 0,01040602 0,01945544 ! cAMP-dependent protein kinase regulator activity GO:0008603 14 14 0,000 0,01040602 0,01944525 ! ephrin receptor activity GO:0005003 16 14 0,000 0,01040602 0,01943508 ! protein polyubiquitination GO:0000209 15 14 0,000 0,01040602 0,01942492 ! glycine metabolic process GO:0006544 15 14 0,000 0,01040602 0,01941478 ! plasma membrane organization GO:0007009 14 14 0,000 0,01040602 0,01940464 ! tyrosine metabolic process GO:0006570 16 14 0,000 0,01040602 0,01939451 ! response to retinoic acid GO:0032526 14 14 0,000 0,01040602 0,01938439 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 16 14 0,000 0,01040602 0,01937429 ! lysosomal transport GO:0007041 14 14 0,000 0,01040602 0,01936419 ! rough endoplasmic reticulum GO:0005791 14 14 0,000 0,01040602 0,0193541 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 14 14 0,000 0,01040602 0,01934403 ! regulation of the force of heart contraction GO:0002026 15 14 0,000 0,01040602 0,01933397 ! bone mineralization GO:0030282 14 14 0,000 0,01040602 0,01932391 ! protein kinase activator activity GO:0030295 14 14 0,000 0,01040602 0,01931387 ! NLS-bearing substrate import into nucleus GO:0006607 15 14 0,000 0,01040602 0,01930383 ! cerebellum development GO:0021549 15 14 0,000 0,01040602 0,01929381 ! G1 phase GO:0051318 14 14 0,000 0,01040602 0,0192838 ! negative regulation of blood coagulation GO:0030195 16 14 0,000 0,01040602 0,0192738 ! negative regulation of protein secretion GO:0050709 14 14 0,000 0,01040602 0,01926381 ! water homeostasis GO:0030104 14 14 0,000 0,01040602 0,01925382 ! peptide hormone binding GO:0017046 14 14 0,000 0,01040602 0,01924385 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,01040602 0,01923389 ! glutamine family amino acid biosynthetic process GO:0009084 15 14 0,000 0,01040602 0,01922394 ! regulation of ATPase activity GO:0043462 15 14 0,000 0,01040602 0,019214 ! racemase and epimerase activity GO:0016854 14 14 0,000 0,01040602 0,01920407 ! regulation of leukocyte mediated cytotoxicity GO:0001910 18 14 0,000 0,01040602 0,01919415 ! positive regulation of calcium ion transport GO:0051928 17 14 0,000 0,01040602 0,01918424 ! regulation of blood vessel endothelial cell migration GO:0043535 14 14 0,000 0,01040602 0,01917435 ! regulation of calcium-mediated signaling GO:0050848 16 14 0,000 0,01040602 0,01916446 ! positive regulation of synaptic transmission GO:0050806 14 14 0,000 0,01040602 0,01915458 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 16 14 0,000 0,01040602 0,01914471 ! lactation GO:0007595 15 14 0,000 0,01040602 0,01913485 ! reproductive cellular process GO:0048610 14 14 0,000 0,01040602 0,019125 ! positive regulation of cell killing GO:0031343 18 14 0,000 0,01040602 0,01911517 ! sulfur amino acid biosynthetic process GO:0000097 15 14 0,000 0,01040602 0,01910534 ! dicarboxylic acid transport GO:0006835 14 14 0,000 0,01040602 0,01909552 ! inorganic anion exchanger activity GO:0005452 15 14 0,000 0,01040602 0,01908571 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 15 14 0,000 0,01040602 0,01907591 ! negative regulation of cytokine biosynthetic process GO:0042036 14 14 0,000 0,01040602 0,01906613 ! negative regulation of ion transport GO:0043271 14 14 0,000 0,01040602 0,01905635 ! retinoic acid receptor binding GO:0042974 14 14 0,000 0,01040602 0,01904658 ! startle response GO:0001964 14 14 0,000 0,01040602 0,01903682 ! 2 iron, 2 sulfur cluster binding GO:0051537 14 14 0,000 0,01040602 0,01902708 ! activation of MAPKK activity GO:0000186 15 14 0,000 0,01040602 0,01901734 ! response to hexose stimulus GO:0009746 14 14 0,000 0,01040602 0,01900761 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! cytokine metabolic process GO:0042107 14 14 0,000 0,01040602 0,01899789 ! organic alcohol transport GO:0015850 15 14 0,000 0,01040602 0,01898819 ! preassembly of GPI anchor in ER membrane GO:0016254 15 14 0,000 0,01040602 0,01897849 ! calcium ion transmembrane transporter activity GO:0015085 16 14 0,000 0,01040602 0,0189688 ! eukaryotic translation initiation factor 4F complex GO:0016281 14 14 0,000 0,01040602 0,01895912 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,01040602 0,01894945 ! L-amino acid transport GO:0015807 14 14 0,000 0,01040602 0,0189398 ! microfilament motor activity GO:0000146 14 14 0,000 0,01040602 0,01893015 ! stem cell development GO:0048864 14 14 0,000 0,01040602 0,01892051 GO:0019827|stem cell maintenance, ! positive regulation of protein import into nucleus GO:0042307 15 14 0,000 0,01040602 0,01891088 ! DNA replication initiation GO:0006270 14 14 0,000 0,01040602 0,01890126 ! T cell differentiation in the thymus GO:0033077 18 14 0,000 0,01040602 0,01889165 ! regulation of cellular pH GO:0030641 14 14 0,000 0,01040602 0,01888205 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,01040602 0,01887246 ! calcium activated cation channel activity GO:0005227 16 14 0,000 0,01040602 0,01886288 ! sulfuric ester hydrolase activity GO:0008484 15 14 0,000 0,01040602 0,01885331 ! serotonin receptor activity GO:0004993 14 14 0,000 0,01040602 0,01884375 ! positive regulation of bone mineralization GO:0030501 15 14 0,000 0,01040602 0,0188342 ! synaptic transmission, cholinergic GO:0007271 15 14 0,000 0,01040602 0,01882466 ! dopamine metabolic process GO:0042417 17 14 0,000 0,01040602 0,01881513 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,01040602 0,01880561 ! ion gated channel activity GO:0022839 16 14 0,000 0,01040602 0,0187961 ! male genitalia development GO:0030539 14 14 0,000 0,01040602 0,01878659 ! regulation of axon extension GO:0030516 15 14 0,000 0,01040602 0,0187771 ! regulation of BMP signaling pathway GO:0030510 14 14 0,000 0,01040602 0,01876762 ! estrogen receptor signaling pathway GO:0030520 14 14 0,000 0,01040602 0,01875814 ! interleukin-1 receptor binding GO:0005149 14 14 0,000 0,01040602 0,01874868 ! defense response to virus GO:0051607 19 14 0,000 0,01040602 0,01873922 ! cadherin binding GO:0045296 16 14 0,000 0,01040602 0,01872978 ! negative regulation of hormone secretion GO:0046888 16 15 0,000 0,01114552 0,02005071 ! nuclear replication fork GO:0043596 16 15 0,000 0,01114552 0,02004061 ! phosphoinositide phosphorylation GO:0046854 16 15 0,000 0,01114552 0,02003053 GO:0046834|lipid phosphorylation, ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,01114552 0,02002045 ! cardiac muscle contraction GO:0060048 16 15 0,000 0,01114552 0,02001039 ! polysome GO:0005844 16 15 0,000 0,01114552 0,02000033 ! mitotic chromosome condensation GO:0007076 15 15 0,000 0,01114552 0,01999029 ! regulation of viral genome replication GO:0045069 15 15 0,000 0,01114552 0,01998025 ! regulation of survival gene product expression GO:0045884 15 15 0,000 0,01114552 0,01997022 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 15 0,000 0,01114552 0,01996021 ! glycoprotein catabolic process GO:0006516 15 15 0,000 0,01114552 0,0199502 ! DNA duplex unwinding GO:0032508 15 15 0,000 0,01114552 0,01994021 GO:0032392|DNA geometric change, ! glutamine metabolic process GO:0006541 16 15 0,000 0,01114552 0,01993022 ! proton-transporting V-type ATPase complex GO:0033176 15 15 0,000 0,01114552 0,01992025 ! response to vitamin A GO:0033189 15 15 0,000 0,01114552 0,01991028 ! protease binding GO:0002020 16 15 0,000 0,01114552 0,01990033 ! regulation of ion transmembrane transporter activity GO:0032412 15 15 0,000 0,01114552 0,01989038 ! actin filament bundle formation GO:0051017 15 15 0,000 0,01114552 0,01988045 ! calcium ion-dependent exocytosis GO:0017156 15 15 0,000 0,01114552 0,01987052 ! purine nucleoside monophosphate metabolic process GO:0009126 16 15 0,000 0,01114552 0,01986061 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! protein export from nucleus GO:0006611 15 15 0,000 0,01114552 0,0198507 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,01114552 0,01984081 ! positive regulation of biomineral formation GO:0070169 16 15 0,000 0,01114552 0,01983092 ! positive regulation of oxidoreductase activity GO:0051353 15 15 0,000 0,01114552 0,01982104 ! filopodium GO:0030175 15 15 0,000 0,01114552 0,01981118 ! negative regulation of inflammatory response GO:0050728 15 15 0,000 0,01114552 0,01980132 ! positive regulation of transmission of nerve impulse GO:0051971 15 15 0,000 0,01114552 0,01979148 ! branched chain family amino acid metabolic process GO:0009081 15 15 0,000 0,01114552 0,01978164 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01114552 0,01977181 ! heme biosynthetic process GO:0006783 15 15 0,000 0,01114552 0,019762 ! SMAD binding GO:0046332 16 15 0,000 0,01114552 0,01975219 ! nerve development GO:0021675 16 15 0,000 0,01114552 0,01974239 ! epithelial to mesenchymal transition GO:0001837 16 15 0,000 0,01114552 0,0197326 ! mannose binding GO:0005537 15 15 0,000 0,01114552 0,01972282 ! phosphoprotein binding GO:0051219 17 15 0,000 0,01114552 0,01971306 ! mismatched DNA binding GO:0030983 15 15 0,000 0,01114552 0,0197033 ! antigen receptor-mediated signaling pathway GO:0050851 21 15 0,000 0,01114552 0,01969355 ! regulation of skeletal muscle tissue development GO:0048641 15 15 0,000 0,01114552 0,01968381 ! synaptonemal complex GO:0000795 15 15 0,000 0,01114552 0,01967408 ! N-terminal protein amino acid modification GO:0031365 16 15 0,000 0,01114552 0,01966436 ! positive regulation of protein complex assembly GO:0031334 15 15 0,000 0,01114552 0,01965465 ! water transport GO:0006833 15 15 0,000 0,01114552 0,01964494 GO:0042044|fluid transport, ! phosphatidylinositol metabolic process GO:0046488 16 15 0,000 0,01114552 0,01963525 ! viral genome replication GO:0019079 15 15 0,000 0,01114552 0,01962557 ! phosphatidylcholine metabolic process GO:0046470 17 15 0,000 0,01114552 0,0196159 ! inositol metabolic process GO:0006020 15 15 0,000 0,01114552 0,01960624 ! sulfate transport GO:0008272 15 15 0,000 0,01114552 0,01959658 ! protein-lipid complex GO:0032994 15 15 0,000 0,01114552 0,01958694 GO:0034358|plasma lipoprotein particle, ! positive regulation of ion transport GO:0043270 18 15 0,000 0,01114552 0,0195773 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 15 15 0,000 0,01114552 0,01956768 ! heart looping GO:0001947 15 15 0,000 0,01114552 0,01955806 ! isoprenoid biosynthetic process GO:0008299 16 15 0,000 0,01114552 0,01954846 ! protein histidine kinase activity GO:0004673 16 15 0,000 0,01114552 0,01953886 GO:0000155|two-component sensor activity, ! cardiac muscle tissue development GO:0048738 15 15 0,000 0,01114552 0,01952927 ! regulation of striated muscle contraction GO:0006942 16 15 0,000 0,01114552 0,0195197 ! response to osmotic stress GO:0006970 16 15 0,000 0,01114552 0,01951013 ! fructose metabolic process GO:0006000 15 15 0,000 0,01114552 0,01950057 ! ubiquitin binding GO:0043130 15 15 0,000 0,01114552 0,01949102 ! vesicle coating GO:0006901 16 15 0,000 0,01114552 0,01948148 ! DNA integration GO:0015074 16 15 0,000 0,01114552 0,01947195 ! alcohol binding GO:0043178 16 15 0,000 0,01114552 0,01946242 ! disulfide oxidoreductase activity GO:0015036 15 15 0,000 0,01114552 0,01945291 ! intermediate filament cytoskeleton organization GO:0045104 16 15 0,000 0,01114552 0,01944341 ! regulation of vasodilation GO:0042312 15 15 0,000 0,01114552 0,01943392 ! genitalia development GO:0048806 15 15 0,000 0,01114552 0,01942443 ! structural constituent of eye lens GO:0005212 15 15 0,000 0,01114552 0,01941496 ! regulation of monooxygenase activity GO:0032768 15 15 0,000 0,01114552 0,01940549 ! voltage-gated sodium channel activity GO:0005248 17 15 0,000 0,01114552 0,01939603 ! ribonucleoprotein binding GO:0043021 16 15 0,000 0,01114552 0,01938658 ! proton-transporting ATP synthase complex GO:0045259 15 15 0,000 0,01114552 0,01937715 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 15 15 0,000 0,01114552 0,01936772 ! regulation of immunoglobulin production GO:0002637 19 15 0,000 0,01114552 0,0193583 ! retinoic acid receptor activity GO:0003708 15 15 0,000 0,01114552 0,01934889 ! receptor activator activity GO:0030546 15 15 0,000 0,01114552 0,01933948 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 15 15 0,000 0,01114552 0,01933009 ! protein transmembrane transporter activity GO:0008320 15 15 0,000 0,01114552 0,01932071 ! histone binding GO:0042393 15 15 0,000 0,01114552 0,01931133 ! phosphoinositide 3-kinase activity GO:0035004 16 15 0,000 0,01114552 0,01930197 ! sialyltransferase activity GO:0008373 15 15 0,000 0,01114552 0,01929261 ! platelet-derived growth factor receptor binding GO:0005161 16 15 0,000 0,01114552 0,01928326 ! drug transporter activity GO:0015238 15 15 0,000 0,01114552 0,01927393 ! negative regulation of homeostatic process GO:0032845 15 15 0,000 0,01114552 0,0192646 ! phosphoinositide 3-kinase complex GO:0005942 16 15 0,000 0,01114552 0,01925528 ! binding of sperm to zona pellucida GO:0007339 16 15 0,000 0,01114552 0,01924597 ! peptide hormone processing GO:0016486 17 15 0,000 0,01114552 0,01923666 ! aldo-keto reductase activity GO:0004033 15 15 0,000 0,01114552 0,01922737 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,01114552 0,01921809 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 16 16 0,000 0,01188453 0,02048245 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,01188453 0,02047257 ! positive regulation of hormone secretion GO:0046887 17 16 0,000 0,01188453 0,0204627 ! protein amino acid ADP-ribosylation GO:0006471 18 16 0,000 0,01188453 0,02045284 ! response to vitamin GO:0033273 16 16 0,000 0,01188453 0,02044299 ! gene silencing by RNA GO:0031047 16 16 0,000 0,01188453 0,02043314 ! regulation of postsynaptic membrane potential GO:0060078 18 16 0,000 0,01188453 0,02042331 ! kinesin complex GO:0005871 16 16 0,000 0,01188453 0,02041349 ! cornified envelope GO:0001533 18 16 0,000 0,01188453 0,02040367 ! regulation of transmembrane transporter activity GO:0022898 16 16 0,000 0,01188453 0,02039387 GO:0032409|regulation of transporter activity, ! negative regulation of epithelial cell proliferation GO:0050680 17 16 0,000 0,01188453 0,02038407 ! pyrimidine ribonucleotide metabolic process GO:0009218 18 16 0,000 0,01188453 0,02037429 ! pituitary gland development GO:0021983 16 16 0,000 0,01188453 0,02036451 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 18 16 0,000 0,01188453 0,02035474 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 19 16 0,000 0,01188453 0,02034499 ! cell-substrate junction assembly GO:0007044 18 16 0,000 0,01188453 0,02033524 ! peptidyl-serine phosphorylation GO:0018105 16 16 0,000 0,01188453 0,0203255 ! branching involved in ureteric bud morphogenesis GO:0001658 16 16 0,000 0,01188453 0,02031577 GO:0060675|ureteric bud morphogenesis, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 16 16 0,000 0,01188453 0,02030605 ! nucleobase metabolic process GO:0009112 19 16 0,000 0,01188453 0,02029634 ! beta-catenin binding GO:0008013 17 16 0,000 0,01188453 0,02028664 ! regulation of steroid metabolic process GO:0019218 17 16 0,000 0,01188453 0,02027694 ! neuron recognition GO:0008038 17 16 0,000 0,01188453 0,02026726 ! oogenesis GO:0048477 19 16 0,000 0,01188453 0,02025759 ! low-density lipoprotein binding GO:0030169 17 16 0,000 0,01188453 0,02024792 ! clathrin vesicle coat GO:0030125 19 16 0,000 0,01188453 0,02023826 ! COPI-coated vesicle GO:0030137 16 16 0,000 0,01188453 0,02022862 ! sphingolipid biosynthetic process GO:0030148 16 16 0,000 0,01188453 0,02021898 ! biomineral formation GO:0031214 16 16 0,000 0,01188453 0,02020935 ! vitamin transport GO:0051180 16 16 0,000 0,01188453 0,02019973 ! folic acid and derivative metabolic process GO:0006760 16 16 0,000 0,01188453 0,02019012 ! organic cation transport GO:0015695 16 16 0,000 0,01188453 0,02018052 ! proximal/distal pattern formation GO:0009954 16 16 0,000 0,01188453 0,02017093 ! regulation of glucose import GO:0046324 17 16 0,000 0,01188453 0,02016135 GO:0010827|regulation of glucose transport, ! aromatic compound biosynthetic process GO:0019438 17 16 0,000 0,01188453 0,02015178 ! aromatic compound catabolic process GO:0019439 18 16 0,000 0,01188453 0,02014221 ! negative regulation of coagulation GO:0050819 18 16 0,000 0,01188453 0,02013266 ! tRNA binding GO:0000049 16 16 0,000 0,01188453 0,02012311 ! regulation of cell killing GO:0031341 20 16 0,000 0,01188453 0,02011357 ! negative regulation of defense response GO:0031348 16 16 0,000 0,01188453 0,02010405 ! regulation of neuronal synaptic plasticity GO:0048168 16 16 0,000 0,01188453 0,02009453 ! hindlimb morphogenesis GO:0035137 16 16 0,000 0,01188453 0,02008502 ! bile acid metabolic process GO:0008206 16 16 0,000 0,01188453 0,02007552 ! axis specification GO:0009798 16 16 0,000 0,01188453 0,02006602 ! adult walking behavior GO:0007628 17 16 0,000 0,01188453 0,02005654 ! C-C chemokine binding GO:0019957 16 16 0,000 0,01188453 0,02004707 GO:0016493|C-C chemokine receptor activity, ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 18 16 0,000 0,01188453 0,0200376 ! protein phosphatase binding GO:0019903 17 16 0,000 0,01188453 0,02002815 ! epidermis morphogenesis GO:0048730 16 16 0,000 0,01188453 0,0200187 ! acyl-CoA dehydrogenase activity GO:0003995 16 16 0,000 0,01188453 0,02000926 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01188453 0,01999983 ! SH2 domain binding GO:0042169 19 16 0,000 0,01188453 0,01999041 ! UDP-galactosyltransferase activity GO:0035250 17 16 0,000 0,01188453 0,019981 ! RNA methyltransferase activity GO:0008173 16 16 0,000 0,01188453 0,0199716 ! neutral amino acid transport GO:0015804 16 16 0,000 0,01188453 0,0199622 ! glucuronosyltransferase activity GO:0015020 17 16 0,000 0,01188453 0,01995282 ! regulation of alpha-beta T cell differentiation GO:0046637 16 16 0,000 0,01188453 0,01994344 ! cellular pigmentation GO:0033059 16 16 0,000 0,01188453 0,01993407 ! mannosidase activity GO:0015923 19 16 0,000 0,01188453 0,01992471 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 16 16 0,000 0,01188453 0,01991536 ! negative regulation of tissue remodeling GO:0034104 16 16 0,000 0,01188453 0,01990602 ! positive regulation of neurological system process GO:0031646 16 16 0,000 0,01188453 0,01989669 ! neuromuscular synaptic transmission GO:0007274 16 16 0,000 0,01188453 0,01988737 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,01188453 0,01987805 ! sperm-egg recognition GO:0035036 17 16 0,000 0,01188453 0,01986875 ! axoneme GO:0005930 16 16 0,000 0,01188453 0,01985945 ! anion exchanger activity GO:0015380 18 17 0,000 0,01262303 0,02108364 ! neuron maturation GO:0042551 18 17 0,000 0,01262303 0,02107379 ! metencephalon development GO:0022037 18 17 0,000 0,01262303 0,02106394 ! regulation of lipid biosynthetic process GO:0046890 18 17 0,000 0,01262303 0,0210541 ! reciprocal meiotic recombination GO:0007131 17 17 0,000 0,01262303 0,02104427 ! hemoglobin complex GO:0005833 18 17 0,000 0,01262303 0,02103445 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 17 17 0,000 0,01262303 0,02102464 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 17 17 0,000 0,01262303 0,02101484 ! protein amino acid deacetylation GO:0006476 17 17 0,000 0,01262303 0,02100505 ! protein amino acid acetylation GO:0006473 19 17 0,000 0,01262303 0,02099526 ! positive regulation of nucleocytoplasmic transport GO:0046824 18 17 0,000 0,01262303 0,02098549 ! regulation of neurotransmitter secretion GO:0046928 18 17 0,000 0,01262303 0,02097572 ! striated muscle thick filament GO:0005863 19 17 0,000 0,01262303 0,02096597 GO:0032982|myosin filament, ! gamma-aminobutyric acid signaling pathway GO:0007214 17 17 0,000 0,01262303 0,02095622 ! glial cell development GO:0021782 17 17 0,000 0,01262303 0,02094648 ! regulation of muscle cell differentiation GO:0051147 17 17 0,000 0,01262303 0,02093675 ! pancreas development GO:0031016 17 17 0,000 0,01262303 0,02092703 ! acetylcholine receptor activity GO:0015464 17 17 0,000 0,01262303 0,02091732 ! nuclear heterochromatin GO:0005720 18 17 0,000 0,01262303 0,02090762 ! calcium-dependent protein binding GO:0048306 19 17 0,000 0,01262303 0,02089793 ! cerebral cortex development GO:0021987 17 17 0,000 0,01262303 0,02088824 ! cellular response to starvation GO:0009267 18 17 0,000 0,01262303 0,02087857 ! signal sequence binding GO:0005048 17 17 0,000 0,01262303 0,0208689 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 17 17 0,000 0,01262303 0,02085925 ! cellular macromolecular complex disassembly GO:0034623 18 17 0,000 0,01262303 0,0208496 ! transforming growth factor beta receptor activity GO:0005024 17 17 0,000 0,01262303 0,02083996 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,01262303 0,02083033 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 17 17 0,000 0,01262303 0,02082071 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 17 0,000 0,01262303 0,02081109 ! actin filament bundle GO:0032432 17 17 0,000 0,01262303 0,02080149 GO:0001725|stress fiber, ! small nucleolar ribonucleoprotein complex GO:0005732 17 17 0,000 0,01262303 0,0207919 ! response to lipopolysaccharide GO:0032496 17 17 0,000 0,01262303 0,02078231 ! plasma membrane fusion GO:0045026 18 17 0,000 0,01262303 0,02077273 ! regulation of protein binding GO:0043393 18 17 0,000 0,01262303 0,02076317 ! recycling endosome GO:0055037 18 17 0,000 0,01262303 0,02075361 ! prostaglandin metabolic process GO:0006693 18 17 0,000 0,01262303 0,02074405 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 19 17 0,000 0,01262303 0,02073451 ! regulation of immunoglobulin mediated immune response GO:0002889 21 17 0,000 0,01262303 0,02072498 GO:0002712|regulation of B cell mediated immunity, ! receptor signaling complex scaffold activity GO:0030159 17 17 0,000 0,01262303 0,02071546 ! positive regulation of cytokine secretion GO:0050715 17 17 0,000 0,01262303 0,02070594 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 17 0,000 0,01262303 0,02069643 ! endodeoxyribonuclease activity GO:0004520 17 17 0,000 0,01262303 0,02068694 ! sphingolipid catabolic process GO:0030149 18 17 0,000 0,01262303 0,02067745 ! steroid catabolic process GO:0006706 17 17 0,000 0,01262303 0,02066796 ! oxygen transport GO:0015671 18 17 0,000 0,01262303 0,02065849 GO:0005344|oxygen transporter activity, ! phosphatidylinositol binding GO:0005545 19 17 0,000 0,01262303 0,02064903 ! hyaluronic acid binding GO:0005540 17 17 0,000 0,01262303 0,02063957 ! negative regulation of T cell activation GO:0050868 17 17 0,000 0,01262303 0,02063013 ! regulation of glucose metabolic process GO:0010906 17 17 0,000 0,01262303 0,02062069 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 17 17 0,000 0,01262303 0,02061126 ! glycosaminoglycan biosynthetic process GO:0006024 17 17 0,000 0,01262303 0,02060184 ! MAP kinase kinase kinase activity GO:0004709 18 17 0,000 0,01262303 0,02059243 ! L-ascorbic acid binding GO:0031418 17 17 0,000 0,01262303 0,02058303 ! negative regulation of endothelial cell proliferation GO:0001937 17 17 0,000 0,01262303 0,02057363 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 18 17 0,000 0,01262303 0,02056425 ! photoreceptor cell maintenance GO:0045494 17 17 0,000 0,01262303 0,02055487 ! response to carbohydrate stimulus GO:0009743 17 17 0,000 0,01262303 0,0205455 ! calmodulin-dependent protein kinase activity GO:0004683 19 17 0,000 0,01262303 0,02053614 ! fucose metabolic process GO:0006004 19 17 0,000 0,01262303 0,02052679 ! D-ribose metabolic process GO:0006014 18 17 0,000 0,01262303 0,02051745 ! membrane budding GO:0006900 18 17 0,000 0,01262303 0,02050811 ! AMP binding GO:0016208 17 17 0,000 0,01262303 0,02049879 ! nuclear ubiquitin ligase complex GO:0000152 17 17 0,000 0,01262303 0,02048947 ! body fluid secretion GO:0007589 18 17 0,000 0,01262303 0,02048016 ! response to fungus GO:0009620 17 17 0,000 0,01262303 0,02047086 ! positive regulation of alpha-beta T cell activation GO:0046635 21 17 0,000 0,01262303 0,02046157 ! intermediate filament-based process GO:0045103 18 17 0,000 0,01262303 0,02045228 ! rRNA binding GO:0019843 17 17 0,000 0,01262303 0,02044301 ! nucleotide-excision repair, DNA gap filling GO:0006297 18 17 0,000 0,01262303 0,02043374 ! regulation of interleukin-2 production GO:0032663 17 17 0,000 0,01262303 0,02042448 ! voltage-gated chloride channel activity GO:0005247 17 17 0,000 0,01262303 0,02041523 ! DNA fragmentation involved in apoptosis GO:0006309 17 17 0,000 0,01262303 0,02040599 ! neutrophil chemotaxis GO:0030593 18 17 0,000 0,01262303 0,02039676 ! long-chain fatty acid transport GO:0015909 17 17 0,000 0,01262303 0,02038753 ! tissue regeneration GO:0042246 17 17 0,000 0,01262303 0,02037831 ! detection of biotic stimulus GO:0009595 18 17 0,000 0,01262303 0,02036911 ! muscle maintenance GO:0046716 18 17 0,000 0,01262303 0,02035991 ! cell-cell junction organization GO:0045216 17 17 0,000 0,01262303 0,02035071 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 17 17 0,000 0,01262303 0,02034153 ! somatic recombination of immunoglobulin gene segments GO:0016447 17 17 0,000 0,01262303 0,02033236 ! cell-cell adherens junction GO:0005913 17 17 0,000 0,01262303 0,02032319 ! triacylglycerol lipase activity GO:0004806 17 17 0,000 0,01262303 0,02031403 ! ATP-dependent DNA helicase activity GO:0004003 17 17 0,000 0,01262303 0,02030488 ! positive regulation of ossification GO:0045778 19 18 0,000 0,01336103 0,02148232 ! pteridine and derivative metabolic process GO:0042558 19 18 0,000 0,01336103 0,02147265 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,01336103 0,02146299 GO:0005763|mitochondrial small ribosomal subunit, ! signal complex assembly GO:0007172 18 18 0,000 0,01336103 0,02145334 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 19 18 0,000 0,01336103 0,0214437 ! limbic system development GO:0021761 18 18 0,000 0,01336103 0,02143407 ! cellular response to hydrogen peroxide GO:0070301 18 18 0,000 0,01336103 0,02142444 GO:0042744|hydrogen peroxide catabolic process, ! MHC class II protein complex GO:0042613 18 18 0,000 0,01336103 0,02141482 ! positive regulation of proteolysis GO:0045862 19 18 0,000 0,01336103 0,02140522 ! deoxyribonucleotide metabolic process GO:0009262 19 18 0,000 0,01336103 0,02139562 ! lysosome organization GO:0007040 18 18 0,000 0,01336103 0,02138603 ! central nervous system neuron development GO:0021954 19 18 0,000 0,01336103 0,02137645 ! fatty acid beta-oxidation GO:0006635 18 18 0,000 0,01336103 0,02136687 ! regulation of viral reproduction GO:0050792 18 18 0,000 0,01336103 0,02135731 ! peptide cross-linking GO:0018149 20 18 0,000 0,01336103 0,02134775 ! ventricular cardiac muscle morphogenesis GO:0055010 19 18 0,000 0,01336103 0,02133821 ! presynaptic membrane GO:0042734 19 18 0,000 0,01336103 0,02132867 ! embryonic digit morphogenesis GO:0042733 20 18 0,000 0,01336103 0,02131914 ! neural crest cell migration GO:0001755 18 18 0,000 0,01336103 0,02130962 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,01336103 0,0213001 ! positive regulation of adaptive immune response GO:0002821 22 18 0,000 0,01336103 0,0212906 ! positive regulation of intracellular transport GO:0032388 19 18 0,000 0,01336103 0,0212811 ! negative regulation of intracellular transport GO:0032387 18 18 0,000 0,01336103 0,02127161 ! peptidyl-serine modification GO:0018209 18 18 0,000 0,01336103 0,02126213 ! cell-cell recognition GO:0009988 19 18 0,000 0,01336103 0,02125266 ! vitamin D receptor binding GO:0042809 19 18 0,000 0,01336103 0,0212432 ! porphyrin biosynthetic process GO:0006779 18 18 0,000 0,01336103 0,02123375 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 18 0,000 0,01336103 0,0212243 ! actin filament-based movement GO:0030048 18 18 0,000 0,01336103 0,02121486 ! Rab GTPase binding GO:0017137 18 18 0,000 0,01336103 0,02120544 ! histone deacetylase activity GO:0004407 19 18 0,000 0,01336103 0,02119601 GO:0033558|protein deacetylase activity, ! protein import into nucleus, docking GO:0000059 18 18 0,000 0,01336103 0,0211866 ! negative regulation of cell cycle process GO:0010948 18 18 0,000 0,01336103 0,0211772 ! glycerol metabolic process GO:0006071 19 18 0,000 0,01336103 0,0211678 ! post-Golgi vesicle-mediated transport GO:0006892 18 18 0,000 0,01336103 0,02115842 ! intra-Golgi vesicle-mediated transport GO:0006891 18 18 0,000 0,01336103 0,02114904 ! aminoglycan catabolic process GO:0006026 18 18 0,000 0,01336103 0,02113967 ! aminoglycan biosynthetic process GO:0006023 18 18 0,000 0,01336103 0,02113031 ! small conjugating protein binding GO:0032182 18 18 0,000 0,01336103 0,02112095 ! memory GO:0007613 19 18 0,000 0,01336103 0,02111161 ! C21-steroid hormone metabolic process GO:0008207 18 18 0,000 0,01336103 0,02110227 ! regulation of DNA recombination GO:0000018 22 18 0,000 0,01336103 0,02109294 ! protein phosphatase type 2A complex GO:0000159 20 18 0,000 0,01336103 0,02108362 ! inactivation of MAPK activity GO:0000188 19 18 0,000 0,01336103 0,02107431 ! pigmentation during development GO:0048066 21 18 0,000 0,01336103 0,021065 ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 18 0,000 0,01336103 0,02105571 ! acetylcholine binding GO:0042166 19 18 0,000 0,01336103 0,02104642 ! neurotransmitter:sodium symporter activity GO:0005328 18 18 0,000 0,01336103 0,02103714 ! neurotransmitter metabolic process GO:0042133 23 18 0,000 0,01336103 0,02102787 ! neuromuscular junction development GO:0007528 21 18 0,000 0,01336103 0,0210186 ! nonmotile primary cilium GO:0031513 19 18 0,000 0,01336103 0,02100935 ! coreceptor activity GO:0015026 18 18 0,000 0,01336103 0,0210001 ! behavioral interaction between organisms GO:0051705 18 18 0,000 0,01336103 0,02099086 ! carbonate dehydratase activity GO:0004089 19 18 0,000 0,01336103 0,02098163 ! cytolysis GO:0019835 18 18 0,000 0,01336103 0,02097241 ! phosphate binding GO:0042301 19 18 0,000 0,01336103 0,02096319 ! transport vesicle membrane GO:0030658 21 18 0,000 0,01336103 0,02095399 ! specific transcriptional repressor activity GO:0016566 18 18 0,000 0,01336103 0,02094479 ! DNA modification GO:0006304 20 18 0,000 0,01336103 0,0209356 ! bicarbonate transmembrane transporter activity GO:0015106 19 18 0,000 0,01336103 0,02092642 ! detection of chemical stimulus GO:0009593 19 18 0,000 0,01336103 0,02091724 ! ionotropic glutamate receptor activity GO:0004970 20 18 0,000 0,01336103 0,02090808 ! aspartic-type endopeptidase activity GO:0004190 19 18 0,000 0,01336103 0,02089892 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 18 18 0,000 0,01336103 0,02088977 ! 3'-5' exonuclease activity GO:0008408 18 18 0,000 0,01336103 0,02088063 ! RNA polymerase II transcription mediator activity GO:0016455 19 18 0,000 0,01336103 0,02087149 ! water-soluble vitamin biosynthetic process GO:0042364 19 18 0,000 0,01336103 0,02086237 ! connexon complex GO:0005922 18 18 0,000 0,01336103 0,02085325 ! solute:hydrogen antiporter activity GO:0015299 18 18 0,000 0,01336103 0,02084414 ! mRNA export from nucleus GO:0006406 21 19 0,000 0,01409853 0,02198508 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 20 19 0,000 0,01409853 0,02197549 ! regulation of interferon-gamma production GO:0032649 20 19 0,000 0,01409853 0,0219659 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 20 19 0,000 0,01409853 0,02195632 ! anion:anion antiporter activity GO:0015301 20 19 0,000 0,01409853 0,02194675 ! cAMP metabolic process GO:0046058 19 19 0,000 0,01409853 0,02193718 ! spindle microtubule GO:0005876 20 19 0,000 0,01409853 0,02192763 ! ovarian follicle development GO:0001541 19 19 0,000 0,01409853 0,02191808 ! retinoid metabolic process GO:0001523 19 19 0,000 0,01409853 0,02190855 GO:0016101|diterpenoid metabolic process, ! caspase activator activity GO:0008656 19 19 0,000 0,01409853 0,02189902 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 21 19 0,000 0,01409853 0,02188949 ! vacuolar transport GO:0007034 19 19 0,000 0,01409853 0,02187998 ! threonine-type endopeptidase activity GO:0004298 19 19 0,000 0,01409853 0,02187048 GO:0070003|threonine-type peptidase activity, ! myofibril assembly GO:0030239 19 19 0,000 0,01409853 0,02186098 GO:0055002|striated muscle cell development, ! monocarboxylic acid transmembrane transporter activity GO:0008028 20 19 0,000 0,01409853 0,02185149 ! positive regulation of multicellular organism growth GO:0040018 19 19 0,000 0,01409853 0,02184201 ! cell projection membrane GO:0031253 20 19 0,000 0,01409853 0,02183254 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,01409853 0,02182308 ! transcriptional repressor complex GO:0017053 19 19 0,000 0,01409853 0,02181362 ! vitamin A metabolic process GO:0006776 19 19 0,000 0,01409853 0,02180417 ! positive regulation of myeloid cell differentiation GO:0045639 20 19 0,000 0,01409853 0,02179473 ! negative regulation of myeloid cell differentiation GO:0045638 19 19 0,000 0,01409853 0,0217853 ! glutamine family amino acid catabolic process GO:0009065 21 19 0,000 0,01409853 0,02177588 ! leukotriene biosynthetic process GO:0019370 19 19 0,000 0,01409853 0,02176647 GO:0043450|alkene biosynthetic process, ! gas transport GO:0015669 20 19 0,000 0,01409853 0,02175706 ! retinoid binding GO:0005501 19 19 0,000 0,01409853 0,02174766 GO:0019840|isoprenoid binding, ! peptide hormone secretion GO:0030072 20 19 0,000 0,01409853 0,02173827 ! protein stabilization GO:0050821 20 19 0,000 0,01409853 0,02172889 ! cellular monovalent inorganic cation homeostasis GO:0030004 20 19 0,000 0,01409853 0,02171952 ! myeloid leukocyte differentiation GO:0002573 21 19 0,000 0,01409853 0,02171015 ! microtubule-based transport GO:0010970 19 19 0,000 0,01409853 0,02170079 ! protein complex scaffold GO:0032947 19 19 0,000 0,01409853 0,02169144 ! SNAP receptor activity GO:0005484 21 19 0,000 0,01409853 0,0216821 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,01409853 0,02167277 GO:0006479|protein amino acid methylation, ! regulation of systemic arterial blood pressure by hormone GO:0001990 19 19 0,000 0,01409853 0,02166344 GO:0050886|endocrine process, ! visual behavior GO:0007632 22 19 0,000 0,01409853 0,02165412 GO:0008542|visual learning, ! 4 iron, 4 sulfur cluster binding GO:0051539 21 19 0,000 0,01409853 0,02164481 ! glycoprotein binding GO:0001948 23 19 0,000 0,01409853 0,02163551 ! sensory perception of taste GO:0050909 19 19 0,000 0,01409853 0,02162622 ! myoblast differentiation GO:0045445 19 19 0,000 0,01409853 0,02161693 ! cell differentiation in spinal cord GO:0021515 19 19 0,000 0,01409853 0,02160766 ! immune response-activating cell surface receptor signaling pathway GO:0002429 25 19 0,000 0,01409853 0,02159839 ! myosin binding GO:0017022 19 19 0,000 0,01409853 0,02158912 ! organic acid:sodium symporter activity GO:0005343 19 19 0,000 0,01409853 0,02157987 ! cell aging GO:0007569 19 19 0,000 0,01409853 0,02157062 ! stem cell differentiation GO:0048863 19 19 0,000 0,01409853 0,02156139 ! regulation of myeloid leukocyte differentiation GO:0002761 21 19 0,000 0,01409853 0,02155216 ! heart process GO:0003015 20 19 0,000 0,01409853 0,02154293 GO:0060047|heart contraction, ! mismatch repair GO:0006298 19 19 0,000 0,01409853 0,02153372 ! secretory granule membrane GO:0030667 20 19 0,000 0,01409853 0,02152451 ! MHC protein binding GO:0042287 19 19 0,000 0,01409853 0,02151531 ! extracellular-glutamate-gated ion channel activity GO:0005234 21 19 0,000 0,01409853 0,02150612 ! chloride transmembrane transporter activity GO:0015108 20 19 0,000 0,01409853 0,02149694 ! GABA-A receptor activity GO:0004890 20 19 0,000 0,01409853 0,02148777 ! response to cytokine stimulus GO:0034097 20 19 0,000 0,01409853 0,0214786 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,01409853 0,02146944 ! translation elongation factor activity GO:0003746 22 19 0,000 0,01409853 0,02146029 ! insulin receptor binding GO:0005158 20 19 0,000 0,01409853 0,02145114 ! phosphoprotein phosphatase inhibitor activity GO:0004864 21 19 0,000 0,01409853 0,02144201 ! protein secretion GO:0009306 20 20 0,000 0,01483552 0,02255328 ! positive regulation of angiogenesis GO:0045766 22 20 0,000 0,01483552 0,02254368 ! proteasome core complex GO:0005839 20 20 0,000 0,01483552 0,02253409 ! positive regulation of bone remodeling GO:0046852 21 20 0,000 0,01483552 0,02252451 ! heterophilic cell adhesion GO:0007157 21 20 0,000 0,01483552 0,02251494 ! glutathione transferase activity GO:0004364 20 20 0,000 0,01483552 0,02250538 ! microtubule organizing center organization GO:0031023 20 20 0,000 0,01483552 0,02249582 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 20 20 0,000 0,01483552 0,02248627 ! actomyosin GO:0042641 20 20 0,000 0,01483552 0,02247673 ! positive regulation of innate immune response GO:0045089 20 20 0,000 0,01483552 0,0224672 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 20 0,000 0,01483552 0,02245767 ! vacuole organization GO:0007033 20 20 0,000 0,01483552 0,02244816 ! oxidoreductase activity, acting on heme group of donors GO:0016675 21 20 0,000 0,01483552 0,02243865 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! purine ribonucleoside metabolic process GO:0046128 23 20 0,000 0,01483552 0,02242915 GO:0042278|purine nucleoside metabolic process, ! chromosome condensation GO:0030261 20 20 0,000 0,01483552 0,02241966 ! regulation of exocytosis GO:0017157 21 20 0,000 0,01483552 0,02241018 ! vitamin biosynthetic process GO:0009110 21 20 0,000 0,01483552 0,0224007 ! glycosphingolipid metabolic process GO:0006687 20 20 0,000 0,01483552 0,02239123 ! kinase activator activity GO:0019209 20 20 0,000 0,01483552 0,02238177 ! diencephalon development GO:0021536 20 20 0,000 0,01483552 0,02237232 ! nuclear inner membrane GO:0005637 20 20 0,000 0,01483552 0,02236288 ! positive regulation of locomotion GO:0040017 20 20 0,000 0,01483552 0,02235344 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! synaptic vesicle transport GO:0048489 21 20 0,000 0,01483552 0,02234401 ! proteoglycan biosynthetic process GO:0030166 20 20 0,000 0,01483552 0,02233459 ! regulation of blood coagulation GO:0030193 22 20 0,000 0,01483552 0,02232518 ! positive regulation of osteoblast differentiation GO:0045669 22 20 0,000 0,01483552 0,02231578 ! regulation of generation of precursor metabolites and energy GO:0043467 21 20 0,000 0,01483552 0,02230638 ! ligase activity, forming carbon-sulfur bonds GO:0016877 20 20 0,000 0,01483552 0,02229699 ! phosphorus-oxygen lyase activity GO:0016849 20 20 0,000 0,01483552 0,02228761 ! embryonic organ morphogenesis GO:0048562 22 20 0,000 0,01483552 0,02227824 ! alditol metabolic process GO:0019400 21 20 0,000 0,01483552 0,02226888 ! liver development GO:0001889 20 20 0,000 0,01483552 0,02225952 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 20 0,000 0,01483552 0,02225017 ! chromosome, telomeric region GO:0000781 21 20 0,000 0,01483552 0,02224083 ! calcium-independent cell-cell adhesion GO:0016338 20 20 0,000 0,01483552 0,0222315 ! response to alkaloid GO:0043279 22 20 0,000 0,01483552 0,02222217 ! transmembrane receptor protein phosphatase activity GO:0019198 27 20 0,000 0,01483552 0,02221285 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! smooth muscle contraction GO:0006939 21 20 0,000 0,01483552 0,02220354 ! heme metabolic process GO:0042168 22 20 0,000 0,01483552 0,02219424 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 20 20 0,000 0,01483552 0,02218495 ! sex determination GO:0007530 20 20 0,000 0,01483552 0,02217566 ! negative regulation of protein catabolic process GO:0042177 21 20 0,000 0,01483552 0,02216638 ! peptide secretion GO:0002790 21 20 0,000 0,01483552 0,02215711 ! regulation of alpha-beta T cell activation GO:0046634 24 20 0,000 0,01483552 0,02214785 ! interaction with host GO:0051701 24 20 0,000 0,01483552 0,02213859 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 26 20 0,000 0,01483552 0,02212935 ! vasodilation GO:0042311 21 20 0,000 0,01483552 0,02212011 ! regulation of tumor necrosis factor production GO:0032680 20 20 0,000 0,01483552 0,02211087 ! regulation of chromosome organization GO:0033044 20 20 0,000 0,01483552 0,02210165 ! inward rectifier potassium channel activity GO:0005242 20 20 0,000 0,01483552 0,02209243 ! activation of JUN kinase activity GO:0007257 20 20 0,000 0,01483552 0,02208322 ! cyclic nucleotide binding GO:0030551 22 20 0,000 0,01483552 0,02207402 ! somatic diversification of immunoglobulins GO:0016445 20 20 0,000 0,01483552 0,02206483 ! microvillus GO:0005902 20 20 0,000 0,01483552 0,02205564 ! tumor necrosis factor receptor binding GO:0005164 20 20 0,000 0,01483552 0,02204646 ! ATP-dependent RNA helicase activity GO:0004004 20 20 0,000 0,01483552 0,02203729 ! positive regulation of protein catabolic process GO:0045732 22 21 0,000 0,01557202 0,0231217 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 22 21 0,000 0,01557202 0,02311209 ! oligosaccharide metabolic process GO:0009311 23 21 0,000 0,01557202 0,02310249 ! regulation of anti-apoptosis GO:0045767 21 21 0,000 0,01557202 0,02309289 ! hormone secretion GO:0046879 22 21 0,000 0,01557202 0,02308331 ! protein amino acid O-linked glycosylation GO:0006493 22 21 0,000 0,01557202 0,02307373 ! transition metal ion transmembrane transporter activity GO:0046915 21 21 0,000 0,01557202 0,02306416 ! voltage-gated calcium channel complex GO:0005891 24 21 0,000 0,01557202 0,0230546 GO:0034704|calcium channel complex, ! dicarboxylic acid metabolic process GO:0043648 22 21 0,000 0,01557202 0,02304504 ! protein phosphatase type 2A regulator activity GO:0008601 23 21 0,000 0,01557202 0,02303549 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 24 21 0,000 0,01557202 0,02302596 ! histone-lysine N-methyltransferase activity GO:0018024 23 21 0,000 0,01557202 0,02301643 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! activation of pro-apoptotic gene products GO:0008633 22 21 0,000 0,01557202 0,0230069 ! mitochondrial membrane organization GO:0007006 22 21 0,000 0,01557202 0,02299739 ! central nervous system neuron differentiation GO:0021953 22 21 0,000 0,01557202 0,02298788 ! Golgi stack GO:0005795 25 21 0,000 0,01557202 0,02297838 ! regulation of endothelial cell migration GO:0010594 21 21 0,000 0,01557202 0,02296889 ! muscle cell development GO:0055001 21 21 0,000 0,01557202 0,02295941 ! cholesterol biosynthetic process GO:0006695 22 21 0,000 0,01557202 0,02294993 ! regulation of vasoconstriction GO:0019229 22 21 0,000 0,01557202 0,02294046 ! deacetylase activity GO:0019213 22 21 0,000 0,01557202 0,022931 ! phosphatase inhibitor activity GO:0019212 23 21 0,000 0,01557202 0,02292155 ! regulation of fatty acid metabolic process GO:0019217 22 21 0,000 0,01557202 0,02291211 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,01557202 0,02290267 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! sensory perception of pain GO:0019233 21 21 0,000 0,01557202 0,02289324 ! pentose metabolic process GO:0019321 22 21 0,000 0,01557202 0,02288382 ! collagen fibril organization GO:0030199 22 21 0,000 0,01557202 0,02287441 ! platelet activation GO:0030168 23 21 0,000 0,01557202 0,022865 ! response to glucocorticoid stimulus GO:0051384 22 21 0,000 0,01557202 0,0228556 ! trans-Golgi network transport vesicle GO:0030140 24 21 0,000 0,01557202 0,02284621 ! glutathione metabolic process GO:0006749 21 21 0,000 0,01557202 0,02283683 ! DNA-directed RNA polymerase complex GO:0000428 22 21 0,000 0,01557202 0,02282746 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! terpenoid metabolic process GO:0006721 21 21 0,000 0,01557202 0,02281809 ! cyclase activity GO:0009975 21 21 0,000 0,01557202 0,02280873 ! intramolecular transferase activity GO:0016866 22 21 0,000 0,01557202 0,02279938 ! negative regulation of cytokine production GO:0001818 21 21 0,000 0,01557202 0,02279003 ! fatty acid binding GO:0005504 21 21 0,000 0,01557202 0,0227807 ! gut development GO:0048565 21 21 0,000 0,01557202 0,02277137 ! acetyl-CoA catabolic process GO:0046356 21 21 0,000 0,01557202 0,02276205 GO:0006099|tricarboxylic acid cycle, ! phosphoinositide phospholipase C activity GO:0004435 21 21 0,000 0,01557202 0,02275273 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! protein tetramerization GO:0051262 22 21 0,000 0,01557202 0,02274343 ! regulation of microtubule polymerization or depolymerization GO:0031110 23 21 0,000 0,01557202 0,02273413 ! sulfur amino acid metabolic process GO:0000096 22 21 0,000 0,01557202 0,02272484 ! voltage-gated anion channel activity GO:0008308 21 21 0,000 0,01557202 0,02271556 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,01557202 0,02270628 ! cellular polysaccharide biosynthetic process GO:0033692 21 21 0,000 0,01557202 0,02269701 ! positive regulation of JAK-STAT cascade GO:0046427 22 21 0,000 0,01557202 0,02268775 ! sterol binding GO:0032934 21 21 0,000 0,01557202 0,0226785 ! regulation of chemotaxis GO:0050920 21 21 0,000 0,01557202 0,02266926 ! regulation of carbohydrate metabolic process GO:0006109 22 21 0,000 0,01557202 0,02266002 GO:0010675|regulation of cellular carbohydrate metabolic process, ! superoxide metabolic process GO:0006801 21 21 0,000 0,01557202 0,02265079 ! calcium-dependent cell-cell adhesion GO:0016339 21 21 0,000 0,01557202 0,02264156 ! phosphatase binding GO:0019902 22 21 0,000 0,01557202 0,02263235 ! NAD+ ADP-ribosyltransferase activity GO:0003950 21 21 0,000 0,01557202 0,02262314 ! positive regulation of cytoskeleton organization GO:0051495 21 21 0,000 0,01557202 0,02261394 ! negative regulation of DNA replication GO:0008156 25 21 0,000 0,01557202 0,02260475 ! vesicle targeting GO:0006903 22 21 0,000 0,01557202 0,02259556 ! vesicle docking during exocytosis GO:0006904 21 21 0,000 0,01557202 0,02258639 ! cell structure disassembly during apoptosis GO:0006921 21 21 0,000 0,01557202 0,02257722 ! RNA-dependent ATPase activity GO:0008186 21 21 0,000 0,01557202 0,02256805 ! renal system process GO:0003014 22 21 0,000 0,01557202 0,0225589 ! base-excision repair GO:0006284 21 21 0,000 0,01557202 0,02254975 ! positive regulation of leukocyte mediated immunity GO:0002705 25 21 0,000 0,01557202 0,02254061 GO:0002708|positive regulation of lymphocyte mediated immunity, ! nuclear-transcribed mRNA catabolic process GO:0000956 22 21 0,000 0,01557202 0,02253148 ! apoptotic protease activator activity GO:0016505 21 21 0,000 0,01557202 0,02252235 ! fatty acid transport GO:0015908 21 21 0,000 0,01557202 0,02251323 ! sarcoplasmic reticulum GO:0016529 22 21 0,000 0,01557202 0,02250412 ! positive regulation of tissue remodeling GO:0034105 22 21 0,000 0,01557202 0,02249502 ! collagen catabolic process GO:0030574 21 21 0,000 0,01557202 0,02248592 ! pyrimidine nucleotide biosynthetic process GO:0006221 25 21 0,000 0,01557202 0,02247683 ! regulation of multi-organism process GO:0043900 21 21 0,000 0,01557202 0,02246775 ! ubiquitin-specific protease activity GO:0004843 22 21 0,000 0,01557202 0,02245868 ! positive regulation of DNA replication GO:0045740 23 22 0,000 0,01630802 0,02351067 ! leukocyte adhesion GO:0007159 27 22 0,000 0,01630802 0,02350118 ! glutamate signaling pathway GO:0007215 25 22 0,000 0,01630802 0,0234917 ! potassium channel regulator activity GO:0015459 24 22 0,000 0,01630802 0,02348223 ! peroxisome organization GO:0007031 22 22 0,000 0,01630802 0,02347276 ! cellular response to reactive oxygen species GO:0034614 22 22 0,000 0,01630802 0,02346331 ! polysaccharide catabolic process GO:0000272 22 22 0,000 0,01630802 0,02345386 ! response to starvation GO:0042594 23 22 0,000 0,01630802 0,02344441 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 22 22 0,000 0,01630802 0,02343498 ! coenzyme catabolic process GO:0009109 22 22 0,000 0,01630802 0,02342555 ! regulation of insulin secretion GO:0050796 23 22 0,000 0,01630802 0,02341613 ! membrane depolarization GO:0051899 24 22 0,000 0,01630802 0,02340672 ! somitogenesis GO:0001756 23 22 0,000 0,01630802 0,02339732 ! regulation of cytokine secretion GO:0050707 22 22 0,000 0,01630802 0,02338792 ! natural killer cell activation GO:0030101 22 22 0,000 0,01630802 0,02337853 ! aromatic amino acid family metabolic process GO:0009072 25 22 0,000 0,01630802 0,02336915 ! basal plasma membrane GO:0009925 22 22 0,000 0,01630802 0,02335978 GO:0045178|basal part of cell, ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 22 22 0,000 0,01630802 0,02335041 ! camera-type eye morphogenesis GO:0048593 25 22 0,000 0,01630802 0,02334105 ! telomere organization GO:0032200 23 22 0,000 0,01630802 0,0233317 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 24 22 0,000 0,01630802 0,02332236 GO:0060606|tube closure, ! response to molecule of bacterial origin GO:0002237 22 22 0,000 0,01630802 0,02331302 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 22 0,000 0,01630802 0,02330369 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 22 22 0,000 0,01630802 0,02329437 GO:0016444|somatic cell DNA recombination, ! cortical actin cytoskeleton GO:0030864 22 22 0,000 0,01630802 0,02328506 ! initiation of viral infection GO:0019059 22 22 0,000 0,01630802 0,02327575 ! RNA polymerase complex GO:0030880 23 22 0,000 0,01630802 0,02326645 ! regulation of neurotransmitter transport GO:0051588 23 22 0,000 0,01630802 0,02325716 ! macromolecular complex disassembly GO:0032984 23 22 0,000 0,01630802 0,02324787 ! response to ethanol GO:0045471 25 22 0,000 0,01630802 0,0232386 ! syntaxin binding GO:0019905 23 22 0,000 0,01630802 0,02322933 ! regulation of nitric oxide biosynthetic process GO:0045428 22 22 0,000 0,01630802 0,02322007 ! digestive system process GO:0022600 24 22 0,000 0,01630802 0,02321081 ! neurotransmitter transporter activity GO:0005326 22 22 0,000 0,01630802 0,02320156 ! autophagy GO:0006914 24 22 0,000 0,01630802 0,02319232 ! carbohydrate kinase activity GO:0019200 22 22 0,000 0,01630802 0,02318309 ! neuropeptide hormone activity GO:0005184 23 22 0,000 0,01630802 0,02317387 ! transaminase activity GO:0008483 23 22 0,000 0,01630802 0,02316465 ! sarcoplasm GO:0016528 23 22 0,000 0,01630802 0,02315544 ! metallocarboxypeptidase activity GO:0004181 23 22 0,000 0,01630802 0,02314623 ! cellular response to nutrient levels GO:0031669 23 22 0,000 0,01630802 0,02313704 ! positive regulation of nuclear division GO:0051785 22 22 0,000 0,01630802 0,02312785 GO:0045840|positive regulation of mitosis, ! nerve-nerve synaptic transmission GO:0007270 25 22 0,000 0,01630802 0,02311867 ! small conjugating protein-specific protease activity GO:0019783 24 22 0,000 0,01630802 0,02310949 ! pyrimidine nucleoside metabolic process GO:0006213 25 22 0,000 0,01630802 0,02310033 ! solute:cation antiporter activity GO:0015298 22 22 0,000 0,01630802 0,02309117 ! translational initiation GO:0006413 23 23 0,000 0,01704351 0,02412302 ! NF-kappaB binding GO:0051059 23 23 0,000 0,01704351 0,02411346 ! vesicle docking GO:0048278 23 23 0,000 0,01704351 0,02410391 ! muscle myosin complex GO:0005859 25 23 0,000 0,01704351 0,02409437 ! vasculogenesis GO:0001570 25 23 0,000 0,01704351 0,02408484 ! regulation of innate immune response GO:0045088 23 23 0,000 0,01704351 0,02407531 ! positive regulation of epithelial cell proliferation GO:0050679 24 23 0,000 0,01704351 0,02406579 ! sperm motility GO:0030317 23 23 0,000 0,01704351 0,02405628 ! response to corticosteroid stimulus GO:0031960 24 23 0,000 0,01704351 0,02404677 ! apoptotic nuclear changes GO:0030262 23 23 0,000 0,01704351 0,02403727 ! barbed-end actin filament capping GO:0051016 23 23 0,000 0,01704351 0,02402779 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 24 23 0,000 0,01704351 0,0240183 ! regulation of behavior GO:0050795 23 23 0,000 0,01704351 0,02400883 ! cardiac muscle tissue morphogenesis GO:0055008 24 23 0,000 0,01704351 0,02399936 GO:0060415|muscle tissue morphogenesis, ! cyclic nucleotide biosynthetic process GO:0009190 23 23 0,000 0,01704351 0,0239899 ! leukotriene metabolic process GO:0006691 23 23 0,000 0,01704351 0,02398045 ! positive regulation of T cell differentiation GO:0045582 27 23 0,000 0,01704351 0,023971 ! glycolipid metabolic process GO:0006664 23 23 0,000 0,01704351 0,02396157 ! regulation of ARF GTPase activity GO:0032312 26 23 0,000 0,01704351 0,02395214 ! pallium development GO:0021543 23 23 0,000 0,01704351 0,02394271 ! GABA receptor activity GO:0016917 24 23 0,000 0,01704351 0,0239333 ! positive regulation of MAPKKK cascade GO:0043410 30 23 0,000 0,01704351 0,02392389 ! regulation of response to biotic stimulus GO:0002831 23 23 0,000 0,01704351 0,02391449 ! MHC class II receptor activity GO:0032395 23 23 0,000 0,01704351 0,0239051 ! nicotinamide metabolic process GO:0006769 23 23 0,000 0,01704351 0,02389571 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of neuron differentiation GO:0045665 23 23 0,000 0,01704351 0,02388633 ! aspartate family amino acid metabolic process GO:0009066 24 23 0,000 0,01704351 0,02387696 ! cell surface binding GO:0043498 25 23 0,000 0,01704351 0,0238676 ! collagen binding GO:0005518 27 23 0,000 0,01704351 0,02385824 ! insulin-like growth factor binding GO:0005520 23 23 0,000 0,01704351 0,02384889 ! regulation of amine transport GO:0051952 23 23 0,000 0,01704351 0,02383955 ! tissue homeostasis GO:0001894 24 23 0,000 0,01704351 0,02383022 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 25 23 0,000 0,01704351 0,02382089 ! protein import into nucleus, translocation GO:0000060 25 23 0,000 0,01704351 0,02381157 ! gluconeogenesis GO:0006094 24 23 0,000 0,01704351 0,02380226 ! iron ion transport GO:0006826 24 23 0,000 0,01704351 0,02379296 ! N-acetylglucosamine metabolic process GO:0006044 23 23 0,000 0,01704351 0,02378366 ! molting cycle process GO:0022404 23 23 0,000 0,01704351 0,02377437 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! circadian rhythm GO:0007623 24 23 0,000 0,01704351 0,02376508 ! tube lumen formation GO:0035148 26 23 0,000 0,01704351 0,02375581 ! insulin receptor signaling pathway GO:0008286 28 23 0,000 0,01704351 0,02374654 ! multicellular organismal response to stress GO:0033555 23 23 0,000 0,01704351 0,02373728 ! immune response-activating signal transduction GO:0002757 29 23 0,000 0,01704351 0,02372802 ! lymphocyte proliferation GO:0046651 29 23 0,000 0,01704351 0,02371878 ! fibroblast growth factor receptor signaling pathway GO:0008543 24 23 0,000 0,01704351 0,02370954 ! regulation of bone mineralization GO:0030500 25 23 0,000 0,01704351 0,0237003 ! single-stranded RNA binding GO:0003727 24 23 0,000 0,01704351 0,02369108 ! brush border GO:0005903 25 23 0,000 0,01704351 0,02368186 ! caveola GO:0005901 24 23 0,000 0,01704351 0,02367265 ! gap junction GO:0005921 23 23 0,000 0,01704351 0,02366344 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 25 24 0,000 0,01777851 0,02467433 ! regulation of transmembrane transport GO:0034762 24 24 0,000 0,01777851 0,02466474 ! heterotrimeric G-protein complex GO:0005834 24 24 0,000 0,01777851 0,02465516 ! protein amino acid acylation GO:0043543 26 24 0,000 0,01777851 0,02464559 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 24 0,000 0,01777851 0,02463603 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 25 24 0,000 0,01777851 0,02462647 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,01777851 0,02461692 ! MHC class I protein complex GO:0042612 24 24 0,000 0,01777851 0,02460738 ! G-protein chemoattractant receptor activity GO:0001637 24 24 0,000 0,01777851 0,02459785 GO:0004950|chemokine receptor activity, ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 24 24 0,000 0,01777851 0,02458832 ! early endosome membrane GO:0031901 26 24 0,000 0,01777851 0,0245788 ! primary neural tube formation GO:0014020 26 24 0,000 0,01777851 0,02456929 ! ARF GTPase activator activity GO:0008060 27 24 0,000 0,01777851 0,02455979 ! hydrogen peroxide metabolic process GO:0042743 24 24 0,000 0,01777851 0,02455029 ! immunoglobulin production GO:0002377 28 24 0,000 0,01777851 0,0245408 GO:0002440|production of molecular mediator of immune response, ! lipid kinase activity GO:0001727 26 24 0,000 0,01777851 0,02453132 ! positive regulation of protein secretion GO:0050714 26 24 0,000 0,01777851 0,02452184 ! MHC class I receptor activity GO:0032393 24 24 0,000 0,01777851 0,02451237 ! RNA splicing factor activity, transesterification mechanism GO:0031202 24 24 0,000 0,01777851 0,02450291 ! fat-soluble vitamin metabolic process GO:0006775 24 24 0,000 0,01777851 0,02449346 ! regulation of osteoblast differentiation GO:0045667 27 24 0,000 0,01777851 0,02448401 ! cellular alkene metabolic process GO:0043449 24 24 0,000 0,01777851 0,02447458 ! somatic diversification of immune receptors GO:0002200 24 24 0,000 0,01777851 0,02446514 ! calcium-dependent phospholipid binding GO:0005544 24 24 0,000 0,01777851 0,02445572 ! positive regulation of JUN kinase activity GO:0043507 24 24 0,000 0,01777851 0,0244463 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 26 24 0,000 0,01777851 0,02443689 ! Z disc GO:0030018 27 24 0,000 0,01777851 0,02442749 ! negative regulation of lymphocyte activation GO:0051250 24 24 0,000 0,01777851 0,0244181 ! alkaloid metabolic process GO:0009820 24 24 0,000 0,01777851 0,02440871 ! neuron fate commitment GO:0048663 24 24 0,000 0,01777851 0,02439933 ! DNA catabolic process, endonucleolytic GO:0000737 24 24 0,000 0,01777851 0,02438995 ! glucosamine metabolic process GO:0006041 24 24 0,000 0,01777851 0,02438059 ! regulation of transcription factor import into nucleus GO:0042990 25 24 0,000 0,01777851 0,02437123 ! glucose transport GO:0015758 24 24 0,000 0,01777851 0,02436188 ! dendrite development GO:0016358 26 24 0,000 0,01777851 0,02435253 ! catechol metabolic process GO:0009712 27 24 0,000 0,01777851 0,02434319 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! phospholipase A2 activity GO:0004623 26 24 0,000 0,01777851 0,02433386 ! immune response-regulating signal transduction GO:0002764 30 24 0,000 0,01777851 0,02432454 ! regulation of production of molecular mediator of immune response GO:0002700 28 24 0,000 0,01777851 0,02431522 ! DNA-directed DNA polymerase activity GO:0003887 25 24 0,000 0,01777851 0,02430591 ! synaptogenesis GO:0007416 25 24 0,000 0,01777851 0,02429661 ! selenium binding GO:0008430 24 24 0,000 0,01777851 0,02428732 ! leukocyte proliferation GO:0070661 30 24 0,000 0,01777851 0,02427803 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 26 24 0,000 0,01777851 0,02426875 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 25 25 0,000 0,018513 0,02526173 ! phenol metabolic process GO:0018958 28 25 0,000 0,018513 0,02525208 ! myelination GO:0042552 26 25 0,000 0,018513 0,02524243 ! epidermal growth factor receptor signaling pathway GO:0007173 28 25 0,000 0,018513 0,0252328 ! hexose transport GO:0008645 25 25 0,000 0,018513 0,02522317 GO:0015749|monosaccharide transport, ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 27 25 0,000 0,018513 0,02521355 ! PML body GO:0016605 28 25 0,000 0,018513 0,02520394 ! regulation of cellular ketone metabolic process GO:0010565 26 25 0,000 0,018513 0,02519433 ! negative regulation of cell development GO:0010721 28 25 0,000 0,018513 0,02518474 GO:0050768|negative regulation of neurogenesis, ! regulation of biomineral formation GO:0070167 27 25 0,000 0,018513 0,02517515 ! cell fate determination GO:0001709 25 25 0,000 0,018513 0,02516556 ! regulation of oxidoreductase activity GO:0051341 25 25 0,000 0,018513 0,02515599 ! group transfer coenzyme metabolic process GO:0006752 26 25 0,000 0,018513 0,02514642 ! hormone transport GO:0009914 26 25 0,000 0,018513 0,02513686 ! neuromuscular process controlling balance GO:0050885 26 25 0,000 0,018513 0,0251273 ! porphyrin metabolic process GO:0006778 27 25 0,000 0,018513 0,02511776 GO:0033013|tetrapyrrole metabolic process, ! blastocyst development GO:0001824 25 25 0,000 0,018513 0,02510822 ! regulation of JUN kinase activity GO:0043506 25 25 0,000 0,018513 0,02509868 ! cell adhesion molecule binding GO:0050839 27 25 0,000 0,018513 0,02508916 ! negative regulation of actin filament depolymerization GO:0030835 25 25 0,000 0,018513 0,02507964 ! acetyl-CoA metabolic process GO:0006084 25 25 0,000 0,018513 0,02507013 ! membrane lipid catabolic process GO:0046466 26 25 0,000 0,018513 0,02506063 ! zinc ion transport GO:0006829 26 25 0,000 0,018513 0,02505113 ! heterochromatin GO:0000792 26 25 0,000 0,018513 0,02504164 ! cellular iron ion homeostasis GO:0006879 25 25 0,000 0,018513 0,02503216 ! phototransduction GO:0007602 25 25 0,000 0,018513 0,02502269 ! keratinization GO:0031424 26 25 0,000 0,018513 0,02501322 ! spinal cord development GO:0021510 25 25 0,000 0,018513 0,02500376 ! regulation of smooth muscle contraction GO:0006940 28 25 0,000 0,018513 0,0249943 ! response to toxin GO:0009636 25 25 0,000 0,018513 0,02498486 ! regulation of peptide secretion GO:0002791 26 25 0,000 0,018513 0,02497542 ! determination of left/right symmetry GO:0007368 25 25 0,000 0,018513 0,02496599 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 25 0,000 0,018513 0,02495656 ! regulation of interleukin-6 production GO:0032675 25 25 0,000 0,018513 0,02494715 ! voltage-gated calcium channel activity GO:0005245 28 25 0,000 0,018513 0,02493773 ! phospholipid transport GO:0015914 26 25 0,000 0,018513 0,02492833 ! peptidase activator activity GO:0016504 25 25 0,000 0,018513 0,02491894 ! protein localization in mitochondrion GO:0070585 26 25 0,000 0,018513 0,02490955 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 25 25 0,000 0,018513 0,02490016 ! regulation of microtubule cytoskeleton organization GO:0070507 27 25 0,000 0,018513 0,02489079 ! ethanolamine and derivative metabolic process GO:0042439 28 25 0,000 0,018513 0,02488142 ! small nuclear ribonucleoprotein complex GO:0030532 25 25 0,000 0,018513 0,02487206 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 25 25 0,000 0,018513 0,02486271 ! negative regulation of transcription regulator activity GO:0090048 26 25 0,000 0,018513 0,02485336 GO:0043433|negative regulation of transcription factor activity, ! acetylgalactosaminyltransferase activity GO:0008376 27 25 0,000 0,018513 0,02484402 ! solute:solute antiporter activity GO:0015300 26 26 0,000 0,019247 0,02581932 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 27 26 0,000 0,019247 0,02580963 ! regeneration GO:0031099 26 26 0,000 0,019247 0,02579994 ! cholesterol homeostasis GO:0042632 26 26 0,000 0,019247 0,02579026 GO:0055092|sterol homeostasis, ! peptidyl-tyrosine phosphorylation GO:0018108 27 26 0,000 0,019247 0,02578058 ! ureteric bud development GO:0001657 26 26 0,000 0,019247 0,02577092 ! neural crest cell development GO:0014032 26 26 0,000 0,019247 0,02576126 GO:0014033|neural crest cell differentiation, ! negative regulation of protein kinase cascade GO:0010741 27 26 0,000 0,019247 0,02575161 ! cellular response to oxidative stress GO:0034599 26 26 0,000 0,019247 0,02574196 ! lipid oxidation GO:0034440 26 26 0,000 0,019247 0,02573232 GO:0019395|fatty acid oxidation, ! positive regulation of lymphocyte differentiation GO:0045621 30 26 0,000 0,019247 0,02572269 ! pyridine nucleotide metabolic process GO:0019362 26 26 0,000 0,019247 0,02571307 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 26 26 0,000 0,019247 0,02570345 ! carboxy-lyase activity GO:0016831 26 26 0,000 0,019247 0,02569385 ! myeloid leukocyte activation GO:0002274 27 26 0,000 0,019247 0,02568424 ! negative regulation of neuron apoptosis GO:0043524 26 26 0,000 0,019247 0,02567465 ! negative regulation of catabolic process GO:0009895 28 26 0,000 0,019247 0,02566506 ! lysine N-acetyltransferase activity GO:0004468 26 26 0,000 0,019247 0,02565548 GO:0004402|histone acetyltransferase activity, ! regulation of actin filament depolymerization GO:0030834 26 26 0,000 0,019247 0,02564591 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,019247 0,02563634 ! determination of bilateral symmetry GO:0009855 26 26 0,000 0,019247 0,02562678 GO:0009799|determination of symmetry, ! regulation of cellular catabolic process GO:0031329 28 26 0,000 0,019247 0,02561723 ! pyruvate metabolic process GO:0006090 27 26 0,000 0,019247 0,02560769 ! cellular component assembly involved in morphogenesis GO:0010927 26 26 0,000 0,019247 0,02559815 ! histone methyltransferase activity GO:0042054 29 26 0,000 0,019247 0,02558862 ! regulation of endothelial cell proliferation GO:0001936 27 26 0,000 0,019247 0,0255791 ! chemokine binding GO:0019956 26 26 0,000 0,019247 0,02556958 ! receptor metabolic process GO:0043112 28 26 0,000 0,019247 0,02556007 ! nucleotide kinase activity GO:0019201 30 26 0,000 0,019247 0,02555057 ! histone deacetylase complex GO:0000118 27 26 0,000 0,019247 0,02554108 ! phospholipase C activity GO:0004629 27 26 0,000 0,019247 0,02553159 ! negative regulation of leukocyte activation GO:0002695 26 26 0,000 0,019247 0,02552211 ! receptor regulator activity GO:0030545 26 26 0,000 0,019247 0,02551263 ! galactosyltransferase activity GO:0008378 27 26 0,000 0,019247 0,02550317 ! response to heat GO:0009408 26 26 0,000 0,019247 0,02549371 ! positive regulation of immune effector process GO:0002699 30 26 0,000 0,019247 0,02548426 ! mRNA catabolic process GO:0006402 28 27 0,000 0,0199805 0,02644565 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 28 27 0,000 0,0199805 0,02643585 ! actomyosin structure organization GO:0031032 28 27 0,000 0,0199805 0,02642606 ! nucleotide receptor activity, G-protein coupled GO:0001608 27 27 0,000 0,0199805 0,02641627 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 28 27 0,000 0,0199805 0,0264065 ! iron ion homeostasis GO:0055072 27 27 0,000 0,0199805 0,02639673 ! lipoprotein binding GO:0008034 29 27 0,000 0,0199805 0,02638697 ! deaminase activity GO:0019239 27 27 0,000 0,0199805 0,02637721 ! mesoderm formation GO:0001707 28 27 0,000 0,0199805 0,02636746 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 27 27 0,000 0,0199805 0,02635772 ! phospholipid transporter activity GO:0005548 29 27 0,000 0,0199805 0,02634799 ! neural tube formation GO:0001841 29 27 0,000 0,0199805 0,02633826 ! mitotic sister chromatid segregation GO:0000070 27 27 0,000 0,0199805 0,02632854 ! regulation of smooth muscle cell proliferation GO:0048660 27 27 0,000 0,0199805 0,02631883 ! integrin complex GO:0008305 28 27 0,000 0,0199805 0,02630913 ! nuclear chromatin GO:0000790 28 27 0,000 0,0199805 0,02629943 ! collagen metabolic process GO:0032963 27 27 0,000 0,0199805 0,02628974 ! post-embryonic development GO:0009791 29 27 0,000 0,0199805 0,02628006 ! antigen processing and presentation of peptide antigen GO:0048002 28 27 0,000 0,0199805 0,02627038 ! ovulation cycle process GO:0022602 27 27 0,000 0,0199805 0,02626071 ! SNARE binding GO:0000149 28 27 0,000 0,0199805 0,02625105 ! biogenic amine biosynthetic process GO:0042401 28 27 0,000 0,0199805 0,0262414 ! spindle pole GO:0000922 28 27 0,000 0,0199805 0,02623175 ! anion:cation symporter activity GO:0015296 28 27 0,000 0,0199805 0,02622211 ! trans-Golgi network GO:0005802 29 28 0,000 0,0207135 0,0271741 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 28 0,000 0,0207135 0,02716412 ! cholesterol transport GO:0030301 28 28 0,000 0,0207135 0,02715415 GO:0015918|sterol transport, ! thyroid hormone receptor binding GO:0046966 29 28 0,000 0,0207135 0,02714418 ! dynein complex GO:0030286 29 28 0,000 0,0207135 0,02713422 ! formation of primary germ layer GO:0001704 29 28 0,000 0,0207135 0,02712427 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 30 28 0,000 0,0207135 0,02711433 ! ovulation cycle GO:0042698 28 28 0,000 0,0207135 0,0271044 ! peptidyl-tyrosine modification GO:0018212 29 28 0,000 0,0207135 0,02709447 ! deoxyribonuclease activity GO:0004536 28 28 0,000 0,0207135 0,02708455 ! cofactor catabolic process GO:0051187 30 28 0,000 0,0207135 0,02707463 ! DNA damage checkpoint GO:0000077 31 28 0,000 0,0207135 0,02706473 ! negative regulation of actin filament polymerization GO:0030837 28 28 0,000 0,0207135 0,02705483 ! cortical cytoskeleton GO:0030863 29 28 0,000 0,0207135 0,02704493 ! icosanoid biosynthetic process GO:0046456 29 28 0,000 0,0207135 0,02703505 ! amino sugar metabolic process GO:0006040 28 28 0,000 0,0207135 0,02702517 ! membrane docking GO:0022406 28 28 0,000 0,0207135 0,0270153 ! sister chromatid segregation GO:0000819 28 28 0,000 0,0207135 0,02700544 ! detection of light stimulus involved in sensory perception GO:0050962 28 28 0,000 0,0207135 0,02699558 GO:0050908|detection of light stimulus involved in visual perception, ! cell junction assembly GO:0034329 30 28 0,000 0,0207135 0,02698573 ! complement activation, classical pathway GO:0006958 31 28 0,000 0,0207135 0,02697589 ! multicellular organismal catabolic process GO:0044243 28 28 0,000 0,0207135 0,02696606 ! response to mechanical stimulus GO:0009612 28 28 0,000 0,0207135 0,02695623 ! caspase regulator activity GO:0043028 28 28 0,000 0,0207135 0,02694641 ! ensheathment of neurons GO:0007272 29 28 0,000 0,0207135 0,0269366 GO:0008366|axon ensheathment, ! DNA polymerase activity GO:0034061 29 28 0,000 0,0207135 0,02692679 ! calcium-mediated signaling GO:0019722 28 28 0,000 0,0207135 0,02691699 ! neurotransmitter secretion GO:0007269 29 28 0,000 0,0207135 0,0269072 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 28 28 0,000 0,0207135 0,02689742 ! glycogen metabolic process GO:0005977 29 28 0,000 0,0207135 0,02688764 ! RNA helicase activity GO:0003724 28 28 0,000 0,0207135 0,02687787 ! Rho GTPase activator activity GO:0005100 32 28 0,000 0,0207135 0,02686811 ! symbiosis, encompassing mutualism through parasitism GO:0044403 32 28 0,000 0,0207135 0,02685835 ! transferase activity, transferring nitrogenous groups GO:0016769 30 29 0,000 0,021446 0,02779806 ! spliceosomal snRNP biogenesis GO:0000387 30 29 0,000 0,021446 0,02778797 ! odontogenesis of dentine-containing tooth GO:0042475 30 29 0,000 0,021446 0,02777789 ! scavenger receptor activity GO:0005044 30 29 0,000 0,021446 0,02776782 ! spindle organization GO:0007051 30 29 0,000 0,021446 0,02775776 ! mesoderm morphogenesis GO:0048332 30 29 0,000 0,021446 0,0277477 ! male gonad development GO:0008584 29 29 0,000 0,021446 0,02773765 ! response to organic cyclic substance GO:0014070 31 29 0,000 0,021446 0,02772761 ! negative regulation of MAP kinase activity GO:0043407 30 29 0,000 0,021446 0,02771757 ! sterol biosynthetic process GO:0016126 30 29 0,000 0,021446 0,02770755 ! endocytic vesicle GO:0030139 29 29 0,000 0,021446 0,02769752 ! Rho GTPase binding GO:0017048 32 29 0,000 0,021446 0,02768751 ! serine family amino acid metabolic process GO:0009069 30 29 0,000 0,021446 0,0276775 ! fatty acid catabolic process GO:0009062 30 29 0,000 0,021446 0,02766751 ! regulation of calcium ion transport GO:0051924 32 29 0,000 0,021446 0,02765751 ! negative regulation of protein polymerization GO:0032272 29 29 0,000 0,021446 0,02764753 ! glucan metabolic process GO:0044042 30 29 0,000 0,021446 0,02763755 GO:0006073|cellular glucan metabolic process, ! regulation of synaptic plasticity GO:0048167 29 29 0,000 0,021446 0,02762758 ! proteoglycan metabolic process GO:0006029 30 29 0,000 0,021446 0,02761762 ! xenobiotic metabolic process GO:0006805 29 29 0,000 0,021446 0,02760766 ! negative regulation of response to external stimulus GO:0032102 29 29 0,000 0,021446 0,02759771 ! positive regulation of T cell proliferation GO:0042102 33 29 0,000 0,021446 0,02758777 ! steroid dehydrogenase activity GO:0016229 29 29 0,000 0,021446 0,02757784 ! regulation of protein import into nucleus GO:0042306 30 29 0,000 0,021446 0,02756791 ! clathrin coated vesicle membrane GO:0030665 32 29 0,000 0,021446 0,02755799 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 30 29 0,000 0,021446 0,02754808 ! cytosolic small ribosomal subunit GO:0022627 29 29 0,000 0,021446 0,02753817 ! detection of visible light GO:0009584 29 29 0,000 0,021446 0,02752827 ! tumor necrosis factor receptor superfamily binding GO:0032813 29 29 0,000 0,021446 0,02751838 ! acetylglucosaminyltransferase activity GO:0008375 30 29 0,000 0,021446 0,0275085 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,021446 0,02749862 ! gene silencing GO:0016458 29 29 0,000 0,021446 0,02748875 ! hormone binding GO:0042562 30 30 0,000 0,022178 0,0284168 ! negative regulation of DNA metabolic process GO:0051053 34 30 0,000 0,022178 0,02840661 ! inner ear morphogenesis GO:0042472 31 30 0,000 0,022178 0,02839643 ! GPI anchor biosynthetic process GO:0006506 32 30 0,000 0,022178 0,02838625 ! acrosomal vesicle GO:0001669 32 30 0,000 0,022178 0,02837608 ! negative regulation of DNA binding GO:0043392 31 30 0,000 0,022178 0,02836592 ! triglyceride metabolic process GO:0006641 31 30 0,000 0,022178 0,02835576 ! erythrocyte differentiation GO:0030218 32 30 0,000 0,022178 0,02834561 ! glutamate receptor activity GO:0008066 33 30 0,000 0,022178 0,02833547 ! ceramide metabolic process GO:0006672 30 30 0,000 0,022178 0,02832533 ! cell fate specification GO:0001708 31 30 0,000 0,022178 0,02831521 ! hexose biosynthetic process GO:0019319 32 30 0,000 0,022178 0,02830509 ! PDZ domain binding GO:0030165 32 30 0,000 0,022178 0,02829498 ! AP-type membrane coat adaptor complex GO:0030119 31 30 0,000 0,022178 0,02828487 GO:0030131|clathrin adaptor complex, ! embryonic epithelial tube formation GO:0001838 32 30 0,000 0,022178 0,02827477 ! negative regulation of cell activation GO:0050866 31 30 0,000 0,022178 0,02826468 ! negative regulation of protein transport GO:0051224 30 30 0,000 0,022178 0,0282546 ! negative regulation of protein complex assembly GO:0031333 30 30 0,000 0,022178 0,02824452 ! regulation of JAK-STAT cascade GO:0046425 32 30 0,000 0,022178 0,02823445 ! drug binding GO:0008144 30 30 0,000 0,022178 0,02822439 ! multicellular organismal macromolecule metabolic process GO:0044259 30 30 0,000 0,022178 0,02821433 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 33 30 0,000 0,022178 0,02820429 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,022178 0,02819425 ! regulation of systemic arterial blood pressure GO:0003073 32 30 0,000 0,022178 0,02818421 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 31 30 0,000 0,022178 0,02817419 ! aminopeptidase activity GO:0004177 32 30 0,000 0,022178 0,02816417 ! detection of light stimulus GO:0009583 30 30 0,000 0,022178 0,02815415 ! L-amino acid transmembrane transporter activity GO:0015179 30 30 0,000 0,022178 0,02814415 ! regulation of microtubule-based process GO:0032886 32 30 0,000 0,022178 0,02813415 ! cysteine-type endopeptidase inhibitor activity GO:0004869 32 30 0,000 0,022178 0,02812416 ! meiosis I GO:0007127 31 31 0,000 0,0229095 0,02904148 ! negative regulation of cell adhesion GO:0007162 33 31 0,000 0,0229095 0,02903117 ! striated muscle cell differentiation GO:0051146 31 31 0,000 0,0229095 0,02902087 ! GPI anchor metabolic process GO:0006505 33 31 0,000 0,0229095 0,02901058 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,0229095 0,0290003 ! spliceosome assembly GO:0000245 32 31 0,000 0,0229095 0,02899002 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 32 31 0,000 0,0229095 0,02897975 GO:0004601|peroxidase activity, ! unsaturated fatty acid biosynthetic process GO:0006636 32 31 0,000 0,0229095 0,02896949 ! NAD or NADH binding GO:0051287 31 31 0,000 0,0229095 0,02895923 ! positive regulation of neurogenesis GO:0050769 32 31 0,000 0,0229095 0,02894899 ! cyclic nucleotide metabolic process GO:0009187 31 31 0,000 0,0229095 0,02893875 ! nucleotide catabolic process GO:0009166 32 31 0,000 0,0229095 0,02892851 ! replication fork GO:0005657 32 31 0,000 0,0229095 0,02891829 ! placenta development GO:0001890 31 31 0,000 0,0229095 0,02890807 ! condensed nuclear chromosome GO:0000794 32 31 0,000 0,0229095 0,02889786 ! regulation of pH GO:0006885 31 31 0,000 0,0229095 0,02888765 ! protein methyltransferase activity GO:0008276 36 31 0,000 0,0229095 0,02887746 ! acute-phase response GO:0006953 32 31 0,000 0,0229095 0,02886727 ! peptide transport GO:0015833 32 31 0,000 0,0229095 0,02885709 ! respiratory gaseous exchange GO:0007585 32 31 0,000 0,0229095 0,02884691 ! DNA integrity checkpoint GO:0031570 34 31 0,000 0,0229095 0,02883674 ! Golgi-associated vesicle membrane GO:0030660 34 31 0,000 0,0229095 0,02882658 ! regulation of protein stability GO:0031647 32 31 0,000 0,0229095 0,02881643 ! sarcolemma GO:0042383 33 31 0,000 0,0229095 0,02880628 ! vesicle localization GO:0051648 32 31 0,000 0,0229095 0,02879614 ! microtubule organizing center part GO:0044450 34 31 0,000 0,0229095 0,02878601 ! response to hydrogen peroxide GO:0042542 34 32 0,000 0,02364051 0,02969408 ! DNA helicase activity GO:0003678 34 32 0,000 0,02364051 0,02968364 ! NADP or NADPH binding GO:0050661 33 32 0,000 0,02364051 0,0296732 ! pigment biosynthetic process GO:0046148 34 32 0,000 0,02364051 0,02966278 ! purinergic nucleotide receptor activity GO:0001614 34 32 0,000 0,02364051 0,02965236 GO:0016502|nucleotide receptor activity, ! female gonad development GO:0008585 32 32 0,000 0,02364051 0,02964195 ! late endosome membrane GO:0031902 32 32 0,000 0,02364051 0,02963154 ! positive regulation of cell development GO:0010720 33 32 0,000 0,02364051 0,02962115 ! hindbrain development GO:0030902 35 32 0,000 0,02364051 0,02961076 ! aerobic respiration GO:0009060 32 32 0,000 0,02364051 0,02960037 ! positive regulation of catabolic process GO:0009896 34 32 0,000 0,02364051 0,02959 ! regulation of muscle development GO:0048634 33 32 0,000 0,02364051 0,02957963 GO:0016202|regulation of striated muscle tissue development, ! cation:sugar symporter activity GO:0005402 32 32 0,000 0,02364051 0,02956927 GO:0005351|sugar:hydrogen symporter activity, ! sphingoid metabolic process GO:0046519 32 32 0,000 0,02364051 0,02955892 ! response to ionizing radiation GO:0010212 33 32 0,000 0,02364051 0,02954857 ! flagellum GO:0019861 32 32 0,000 0,02364051 0,02953823 ! regulation of lymphocyte mediated immunity GO:0002706 36 32 0,000 0,02364051 0,0295279 ! I band GO:0031674 35 32 0,000 0,02364051 0,02951757 ! JAK-STAT cascade GO:0007259 34 32 0,000 0,02364051 0,02950726 ! double-stranded RNA binding GO:0003725 33 32 0,000 0,02364051 0,02949695 ! cellular response to insulin stimulus GO:0032869 37 32 0,000 0,02364051 0,02948664 ! adult locomotory behavior GO:0008344 33 32 0,000 0,02364051 0,02947635 ! pyrimidine nucleotide metabolic process GO:0006220 37 32 0,000 0,02364051 0,02946606 ! positive regulation of transcription factor activity GO:0051091 34 33 0,000 0,02437102 0,03036599 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of secretion GO:0051048 34 33 0,000 0,02437102 0,03035539 ! establishment or maintenance of cell polarity GO:0007163 33 33 0,000 0,02437102 0,03034481 ! platelet alpha granule lumen GO:0031093 34 33 0,000 0,02437102 0,03033423 ! negative regulation of binding GO:0051100 34 33 0,000 0,02437102 0,03032366 ! organelle envelope lumen GO:0031970 34 33 0,000 0,02437102 0,0303131 ! protein targeting to membrane GO:0006612 35 33 0,000 0,02437102 0,03030255 ! vesicle coat GO:0030120 36 33 0,000 0,02437102 0,030292 ! endoribonuclease activity GO:0004521 34 33 0,000 0,02437102 0,03028146 ! eye morphogenesis GO:0048592 38 33 0,000 0,02437102 0,03027093 ! embryonic organ development GO:0048568 36 33 0,000 0,02437102 0,0302604 ! monosaccharide biosynthetic process GO:0046364 35 33 0,000 0,02437102 0,03024988 ! glial cell differentiation GO:0010001 33 33 0,000 0,02437102 0,03023937 ! cell junction organization GO:0034330 35 33 0,000 0,02437102 0,03022887 ! tissue remodeling GO:0048771 35 33 0,000 0,02437102 0,03021837 ! segmentation GO:0035282 34 33 0,000 0,02437102 0,03020788 ! positive regulation of gene-specific transcription GO:0043193 34 33 0,000 0,02437102 0,0301974 ! energy coupled proton transport, down electrochemical gradient GO:0015985 33 33 0,000 0,02437102 0,03018693 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 35 33 0,000 0,02437102 0,03017646 ! hormone biosynthetic process GO:0042446 33 33 0,000 0,02437102 0,030166 ! O-acyltransferase activity GO:0008374 33 33 0,000 0,02437102 0,03015555 ! response to xenobiotic stimulus GO:0009410 33 33 0,000 0,02437102 0,0301451 ! cellular amide metabolic process GO:0043603 34 34 0,000 0,02510103 0,03103732 ! sugar transmembrane transporter activity GO:0051119 34 34 0,000 0,02510103 0,03102658 GO:0015144|carbohydrate transmembrane transporter activity, ! neural tube development GO:0021915 36 34 0,000 0,02510103 0,03101584 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 34 0,000 0,02510103 0,03100512 ! neutral lipid metabolic process GO:0006638 35 34 0,000 0,02510103 0,03099439 GO:0006639|acylglycerol metabolic process, ! lipid homeostasis GO:0055088 34 34 0,000 0,02510103 0,03098368 ! telencephalon development GO:0021537 34 34 0,000 0,02510103 0,03097298 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 35 34 0,000 0,02510103 0,03096228 ! integral to Golgi membrane GO:0030173 34 34 0,000 0,02510103 0,03095158 ! intramolecular oxidoreductase activity GO:0016860 35 34 0,000 0,02510103 0,0309409 ! collagen GO:0005581 35 34 0,000 0,02510103 0,03093022 ! development of primary female sexual characteristics GO:0046545 34 34 0,000 0,02510103 0,03091955 GO:0046660|female sex differentiation, ! DNA-directed RNA polymerase activity GO:0003899 35 34 0,000 0,02510103 0,03090889 GO:0034062|RNA polymerase activity, ! leukocyte chemotaxis GO:0030595 35 34 0,000 0,02510103 0,03089824 GO:0060326|cell chemotaxis, ! sodium channel activity GO:0005272 36 34 0,000 0,02510103 0,03088759 ! carboxypeptidase activity GO:0004180 35 34 0,000 0,02510103 0,03087695 ! spermatid development GO:0007286 34 34 0,000 0,02510103 0,03086632 ! BMP signaling pathway GO:0030509 35 34 0,000 0,02510103 0,03085569 ! specific RNA polymerase II transcription factor activity GO:0003704 35 34 0,000 0,02510103 0,03084508 ! positive regulation of DNA metabolic process GO:0051054 40 35 0,000 0,02583055 0,03173061 ! mitotic cell cycle checkpoint GO:0007093 35 35 0,000 0,02583055 0,0317197 ! regulation of intracellular protein transport GO:0033157 37 35 0,000 0,02583055 0,0317088 ! vesicle lumen GO:0031983 37 35 0,000 0,02583055 0,0316979 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! regulation of action potential in neuron GO:0019228 38 35 0,000 0,02583055 0,03168701 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 39 35 0,000 0,02583055 0,03167613 ! cytokine production GO:0001816 35 35 0,000 0,02583055 0,03166526 ! carbon-carbon lyase activity GO:0016830 35 35 0,000 0,02583055 0,03165439 ! embryonic pattern specification GO:0009880 36 35 0,000 0,02583055 0,03164353 ! regulation of metal ion transport GO:0010959 38 35 0,000 0,02583055 0,03163268 ! energy reserve metabolic process GO:0006112 36 35 0,000 0,02583055 0,03162183 ! metalloexopeptidase activity GO:0008235 36 35 0,000 0,02583055 0,031611 ! protein serine/threonine phosphatase complex GO:0008287 38 35 0,000 0,02583055 0,03160017 ! phagocytosis GO:0006909 37 35 0,000 0,02583055 0,03158935 ! regulation of ARF protein signal transduction GO:0032012 40 35 0,000 0,02583055 0,03157853 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 37 35 0,000 0,02583055 0,03156772 ! ion transmembrane transport GO:0034220 35 35 0,000 0,02583055 0,03155693 ! neuropeptide receptor activity GO:0008188 35 35 0,000 0,02583055 0,03154613 ! oxygen binding GO:0019825 36 35 0,000 0,02583055 0,03153535 ! regulation of leukocyte mediated immunity GO:0002703 39 35 0,000 0,02583055 0,03152457 ! erythrocyte homeostasis GO:0034101 37 35 0,000 0,02583055 0,0315138 ! peripheral nervous system development GO:0007422 37 35 0,000 0,02583055 0,03150304 ! female gamete generation GO:0007292 38 35 0,000 0,02583055 0,03149228 ! polyol metabolic process GO:0019751 36 35 0,000 0,02583055 0,03148153 ! negative regulation of adenylate cyclase activity GO:0007194 38 36 0,000 0,02655957 0,032359 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of hormone secretion GO:0046883 38 36 0,000 0,02655957 0,03234796 ! monocarboxylic acid binding GO:0033293 37 36 0,000 0,02655957 0,03233693 ! polysaccharide biosynthetic process GO:0000271 36 36 0,000 0,02655957 0,03232591 ! regulation of axonogenesis GO:0050770 39 36 0,000 0,02655957 0,0323149 ! glycerol ether metabolic process GO:0006662 37 36 0,000 0,02655957 0,03230389 ! regulation of proteolysis GO:0030162 37 36 0,000 0,02655957 0,03229289 ! integral to endoplasmic reticulum membrane GO:0030176 36 36 0,000 0,02655957 0,0322819 ! regulation of adaptive immune response GO:0002819 40 36 0,000 0,02655957 0,03227092 ! oxidoreduction coenzyme metabolic process GO:0006733 37 36 0,000 0,02655957 0,03225994 ! isoprenoid metabolic process GO:0006720 37 36 0,000 0,02655957 0,03224897 ! spermatid differentiation GO:0048515 36 36 0,000 0,02655957 0,03223801 ! phosphoinositide biosynthetic process GO:0046489 38 36 0,000 0,02655957 0,03222705 ! ER to Golgi vesicle-mediated transport GO:0006888 36 36 0,000 0,02655957 0,03221611 ! condensed chromosome kinetochore GO:0000777 37 36 0,000 0,02655957 0,03220517 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 38 36 0,000 0,02655957 0,03219424 ! neuropeptide binding GO:0042923 36 36 0,000 0,02655957 0,03218331 ! organic anion transport GO:0015711 37 36 0,000 0,02655957 0,0321724 ! carbohydrate homeostasis GO:0033500 38 36 0,000 0,02655957 0,03216149 GO:0042593|glucose homeostasis, ! complement activation GO:0006956 39 36 0,000 0,02655957 0,03215058 ! antigen binding GO:0003823 36 36 0,000 0,02655957 0,03213969 ! extrinsic to plasma membrane GO:0019897 36 36 0,000 0,02655957 0,0321288 ! cytokinesis GO:0000910 40 36 0,000 0,02655957 0,03211792 ! coated pit GO:0005905 42 36 0,000 0,02655957 0,03210705 ! protein amino acid N-linked glycosylation GO:0006487 40 37 0,000 0,02728809 0,03297658 ! ribonucleoside metabolic process GO:0009119 43 37 0,000 0,02728809 0,03296542 ! DNA-dependent ATPase activity GO:0008094 39 37 0,000 0,02728809 0,03295427 ! regulation of T cell differentiation GO:0045580 41 37 0,000 0,02728809 0,03294313 ! biopolymer methylation GO:0043414 42 37 0,000 0,02728809 0,032932 ! intrinsic to Golgi membrane GO:0031228 37 37 0,000 0,02728809 0,03292087 ! protein homooligomerization GO:0051260 38 37 0,000 0,02728809 0,03290975 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 38 37 0,000 0,02728809 0,03289864 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 41 37 0,000 0,02728809 0,03288754 ! regulation of T cell proliferation GO:0042129 41 37 0,000 0,02728809 0,03287644 ! multicellular organismal metabolic process GO:0044236 38 37 0,000 0,02728809 0,03286536 ! amino acid binding GO:0016597 40 37 0,000 0,02728809 0,03285428 ! maintenance of protein location GO:0045185 38 37 0,000 0,02728809 0,0328432 ! maintenance of location in cell GO:0051651 38 37 0,000 0,02728809 0,03283214 ! solute:hydrogen symporter activity GO:0015295 37 37 0,000 0,02728809 0,03282108 ! proton-transporting two-sector ATPase complex GO:0016469 37 37 0,000 0,02728809 0,03281003 ! odontogenesis GO:0042476 40 38 0,000 0,02801612 0,03367404 ! organic ether metabolic process GO:0018904 39 38 0,000 0,02801612 0,03366271 ! alcohol biosynthetic process GO:0046165 40 38 0,000 0,02801612 0,03365139 ! monovalent inorganic cation homeostasis GO:0055067 39 38 0,000 0,02801612 0,03364007 ! positive regulation of DNA binding GO:0043388 39 38 0,000 0,02801612 0,03362876 ! B cell differentiation GO:0030183 40 38 0,000 0,02801612 0,03361746 ! clathrin coat GO:0030118 43 38 0,000 0,02801612 0,03360617 ! regulation of endocytosis GO:0030100 39 38 0,000 0,02801612 0,03359489 ! dorsal/ventral pattern formation GO:0009953 38 38 0,000 0,02801612 0,03358361 ! cell growth GO:0016049 40 38 0,000 0,02801612 0,03357234 ! positive regulation of defense response GO:0031349 38 38 0,000 0,02801612 0,03356108 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 38 0,000 0,02801612 0,03354982 ! condensed chromosome, centromeric region GO:0000779 39 38 0,000 0,02801612 0,03353858 ! learning GO:0007612 42 38 0,000 0,02801612 0,03352734 ! negative regulation of protein complex disassembly GO:0043242 40 38 0,000 0,02801612 0,0335161 ! monocarboxylic acid transport GO:0015718 39 38 0,000 0,02801612 0,03350488 ! endosome transport GO:0016197 40 38 0,000 0,02801612 0,03349366 ! hormone-mediated signaling GO:0009755 39 38 0,000 0,02801612 0,03348245 ! N-methyltransferase activity GO:0008170 42 38 0,000 0,02801612 0,03347125 ! cytosolic large ribosomal subunit GO:0022625 38 38 0,000 0,02801612 0,03346006 ! pigment metabolic process GO:0042440 42 38 0,000 0,02801612 0,03344887 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 38 38 0,000 0,02801612 0,03343769 ! RNA modification GO:0009451 39 38 0,000 0,02801612 0,03342652 ! regulation of nucleocytoplasmic transport GO:0046822 41 39 0,000 0,02874365 0,0342831 ! Notch signaling pathway GO:0007219 41 39 0,000 0,02874365 0,03427165 ! induction of apoptosis by extracellular signals GO:0008624 39 39 0,000 0,02874365 0,03426021 ! keratin filament GO:0045095 41 39 0,000 0,02874365 0,03424878 ! ER-Golgi intermediate compartment GO:0005793 42 39 0,000 0,02874365 0,03423735 ! peroxisomal membrane GO:0005778 40 39 0,000 0,02874365 0,03422594 GO:0031903|microbody membrane, ! mitochondrial respiratory chain complex I GO:0005747 39 39 0,000 0,02874365 0,03421453 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! actin filament binding GO:0051015 39 39 0,000 0,02874365 0,03420313 ! regulation of protein secretion GO:0050708 41 39 0,000 0,02874365 0,03419174 ! cis-trans isomerase activity GO:0016859 39 39 0,000 0,02874365 0,03418035 ! regulation of cell morphogenesis involved in differentiation GO:0010769 42 39 0,000 0,02874365 0,03416897 ! viral infectious cycle GO:0019058 39 39 0,000 0,02874365 0,0341576 ! mammary gland development GO:0030879 41 39 0,000 0,02874365 0,03414624 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 39 0,000 0,02874365 0,03413488 ! amine receptor activity GO:0008227 41 39 0,000 0,02874365 0,03412353 ! positive regulation of response to external stimulus GO:0032103 39 39 0,000 0,02874365 0,03411219 ! monosaccharide binding GO:0048029 39 39 0,000 0,02874365 0,03410086 ! NADH dehydrogenase (ubiquinone) activity GO:0008137 39 39 0,000 0,02874365 0,03408953 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! phosphotransferase activity, phosphate group as acceptor GO:0016776 44 40 0,000 0,02947069 0,03494019 ! response to estrogen stimulus GO:0043627 41 40 0,000 0,02947069 0,03492859 ! peptide metabolic process GO:0006518 41 40 0,000 0,02947069 0,034917 ! regulation of Rab protein signal transduction GO:0032483 41 40 0,000 0,02947069 0,03490542 GO:0032313|regulation of Rab GTPase activity, ! T cell differentiation GO:0030217 45 40 0,000 0,02947069 0,03489385 ! regulation of multicellular organism growth GO:0040014 42 40 0,000 0,02947069 0,03488228 ! regulation of gene expression, epigenetic GO:0040029 43 40 0,000 0,02947069 0,03487072 ! neuron migration GO:0001764 42 40 0,000 0,02947069 0,03485917 ! inositol or phosphatidylinositol kinase activity GO:0004428 42 40 0,000 0,02947069 0,03484763 ! structural constituent of muscle GO:0008307 43 40 0,000 0,02947069 0,03483609 ! gliogenesis GO:0042063 40 40 0,000 0,02947069 0,03482457 ! feeding behavior GO:0007631 40 40 0,000 0,02947069 0,03481305 ! nucleus organization GO:0006997 40 40 0,000 0,02947069 0,03480153 ! positive regulation of cytokine biosynthetic process GO:0042108 41 40 0,000 0,02947069 0,03479003 ! sulfur compound biosynthetic process GO:0044272 41 40 0,000 0,02947069 0,03477853 ! inorganic anion transmembrane transporter activity GO:0015103 42 40 0,000 0,02947069 0,03476704 ! chromatin remodeling GO:0006338 43 40 0,000 0,02947069 0,03475556 ! activation of adenylate cyclase activity GO:0007190 42 41 0,000 0,03019724 0,03560064 ! positive regulation of binding GO:0051099 42 41 0,000 0,03019724 0,03558889 ! response to reactive oxygen species GO:0000302 43 41 0,000 0,03019724 0,03557715 ! solute:sodium symporter activity GO:0015370 41 41 0,000 0,03019724 0,03556541 ! regulation of translational initiation GO:0006446 41 41 0,000 0,03019724 0,03555369 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 44 41 0,000 0,03019724 0,03554197 GO:0046328|regulation of JNK cascade, ! mesenchymal cell development GO:0014031 43 41 0,000 0,03019724 0,03553026 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! heterocycle biosynthetic process GO:0018130 43 41 0,000 0,03019724 0,03551855 ! exonuclease activity GO:0004527 42 41 0,000 0,03019724 0,03550686 ! regulation of myeloid cell differentiation GO:0045637 43 41 0,000 0,03019724 0,03549517 ! positive regulation of cytokine production GO:0001819 42 41 0,000 0,03019724 0,03548349 ! hydro-lyase activity GO:0016836 44 41 0,000 0,03019724 0,03547182 ! positive regulation of protein transport GO:0051222 44 41 0,000 0,03019724 0,03546015 ! receptor-mediated endocytosis GO:0006898 43 41 0,000 0,03019724 0,0354485 ! regulation of neuron projection development GO:0010975 44 41 0,000 0,03019724 0,03543685 ! metal cluster binding GO:0051540 43 41 0,000 0,03019724 0,03542521 GO:0051536|iron-sulfur cluster binding, ! development of primary male sexual characteristics GO:0046546 41 41 0,000 0,03019724 0,03541357 ! double-strand break repair GO:0006302 41 41 0,000 0,03019724 0,03540195 ! Rab GTPase activator activity GO:0005097 42 41 0,000 0,03019724 0,03539033 ! RNA catabolic process GO:0006401 44 42 0,000 0,03092328 0,03622935 ! organellar ribosome GO:0000313 43 42 0,000 0,03092328 0,03621746 GO:0005761|mitochondrial ribosome, ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 44 42 0,000 0,03092328 0,03620559 ! damaged DNA binding GO:0003684 42 42 0,000 0,03092328 0,03619372 ! MHC protein complex GO:0042611 42 42 0,000 0,03092328 0,03618186 ! regulation of epithelial cell proliferation GO:0050678 44 42 0,000 0,03092328 0,03617001 ! negative regulation of cell migration GO:0030336 44 42 0,000 0,03092328 0,03615817 ! icosanoid metabolic process GO:0006690 43 42 0,000 0,03092328 0,03614633 ! chemokine activity GO:0008009 42 42 0,000 0,03092328 0,0361345 ! ruffle GO:0001726 44 42 0,000 0,03092328 0,03612268 ! pigmentation GO:0043473 46 42 0,000 0,03092328 0,03611087 ! developmental growth GO:0048589 42 42 0,000 0,03092328 0,03609907 ! methylation GO:0032259 47 42 0,000 0,03092328 0,03608727 ! glycolysis GO:0006096 42 42 0,000 0,03092328 0,03607548 ! morphogenesis of embryonic epithelium GO:0016331 44 42 0,000 0,03092328 0,0360637 ! regulation of tube size GO:0035150 44 42 0,000 0,03092328 0,03605192 GO:0050880|regulation of blood vessel size, ! branching morphogenesis of a tube GO:0048754 43 42 0,000 0,03092328 0,03604016 ! general RNA polymerase II transcription factor activity GO:0016251 44 42 0,000 0,03092328 0,0360284 ! cellular amino acid derivative biosynthetic process GO:0042398 43 42 0,000 0,03092328 0,03601665 ! positive regulation of adenylate cyclase activity GO:0045762 44 43 0,000 0,03164884 0,03684969 ! transferase activity, transferring pentosyl groups GO:0016763 45 43 0,000 0,03164884 0,03683768 ! epithelial cell differentiation GO:0030855 45 43 0,000 0,03164884 0,03682568 ! detection of stimulus involved in sensory perception GO:0050906 43 43 0,000 0,03164884 0,03681368 ! sulfotransferase activity GO:0008146 44 43 0,000 0,03164884 0,03680169 ! cellular polysaccharide metabolic process GO:0044264 44 43 0,000 0,03164884 0,03678971 ! channel regulator activity GO:0016247 46 43 0,000 0,03164884 0,03677774 ! histone modification GO:0016570 44 43 0,000 0,03164884 0,03676578 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 45 43 0,000 0,03164884 0,03675382 ! synaptosome GO:0019717 47 43 0,000 0,03164884 0,03674187 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 45 44 0,000 0,0323739 0,0375714 ! platelet alpha granule GO:0031091 46 44 0,000 0,0323739 0,03755919 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 44 44 0,000 0,0323739 0,03754699 ! regulation of ossification GO:0030278 48 44 0,000 0,0323739 0,0375348 ! cell recognition GO:0008037 46 44 0,000 0,0323739 0,03752262 ! positive regulation of cyclase activity GO:0031281 45 44 0,000 0,0323739 0,03751044 ! regulation of lymphocyte differentiation GO:0045619 48 44 0,000 0,0323739 0,03749828 ! regulation of actin filament polymerization GO:0030833 45 44 0,000 0,0323739 0,03748612 ! cellular component disassembly GO:0022411 45 44 0,000 0,0323739 0,03747397 ! regulation of protein complex disassembly GO:0043244 46 44 0,000 0,0323739 0,03746182 ! regulation of ion transport GO:0043269 47 44 0,000 0,0323739 0,03744969 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 50 44 0,000 0,0323739 0,03743756 ! inner ear development GO:0048839 46 44 0,000 0,0323739 0,03742544 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 48 44 0,000 0,0323739 0,03741333 ! amino acid transmembrane transporter activity GO:0015171 44 44 0,000 0,0323739 0,03740123 ! negative regulation of immune system process GO:0002683 49 44 0,000 0,0323739 0,03738913 ! chemokine receptor binding GO:0042379 44 44 0,000 0,0323739 0,03737704 ! regulation of action potential GO:0001508 50 45 0,000 0,03309847 0,03820123 ! regulation of gene-specific transcription GO:0032583 47 45 0,000 0,03309847 0,03818889 ! cellular amino acid biosynthetic process GO:0008652 47 45 0,000 0,03309847 0,03817656 ! response to temperature stimulus GO:0009266 45 45 0,000 0,03309847 0,03816423 ! nucleoside monophosphate biosynthetic process GO:0009124 50 45 0,000 0,03309847 0,03815191 ! positive regulation of lyase activity GO:0051349 46 45 0,000 0,03309847 0,0381396 ! regulation of neuron apoptosis GO:0043523 45 45 0,000 0,03309847 0,0381273 ! excretion GO:0007588 46 45 0,000 0,03309847 0,038115 ! protein phosphatase regulator activity GO:0019888 49 45 0,000 0,03309847 0,03810271 ! JNK cascade GO:0007254 45 45 0,000 0,03309847 0,03809043 ! SH3/SH2 adaptor activity GO:0005070 48 45 0,000 0,03309847 0,03807816 ! regulation of cell shape GO:0008360 46 45 0,000 0,03309847 0,0380659 ! epithelial tube morphogenesis GO:0060562 47 45 0,000 0,03309847 0,03805364 ! microbody part GO:0044438 46 45 0,000 0,03309847 0,0380414 GO:0044439|peroxisomal part, ! auxiliary transport protein activity GO:0015457 50 46 0,000 0,03382254 0,0388611 ! ATP synthesis coupled electron transport GO:0042773 46 46 0,000 0,03382254 0,0388486 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! microtubule binding GO:0008017 49 46 0,000 0,03382254 0,0388361 ! regulation of inflammatory response GO:0050727 46 46 0,000 0,03382254 0,03882362 ! transport vesicle GO:0030133 49 46 0,000 0,03382254 0,03881115 ! glutamine family amino acid metabolic process GO:0009064 49 46 0,000 0,03382254 0,03879868 ! synapse organization GO:0050808 51 46 0,000 0,03382254 0,03878622 ! nuclear matrix GO:0016363 49 46 0,000 0,03382254 0,03877377 ! striated muscle contraction GO:0006941 49 46 0,000 0,03382254 0,03876132 ! unsaturated fatty acid metabolic process GO:0033559 47 46 0,000 0,03382254 0,03874889 ! antioxidant activity GO:0016209 47 46 0,000 0,03382254 0,03873646 ! activation of caspase activity GO:0006919 49 46 0,000 0,03382254 0,03872404 ! aging GO:0007568 48 46 0,000 0,03382254 0,03871163 ! male sex differentiation GO:0046661 46 46 0,000 0,03382254 0,03869923 ! coated vesicle membrane GO:0030662 49 46 0,000 0,03382254 0,03868683 ! covalent chromatin modification GO:0016569 47 46 0,000 0,03382254 0,03867444 ! protein amino acid lipidation GO:0006497 50 47 0,000 0,03454612 0,03948918 ! stress-activated protein kinase signaling pathway GO:0031098 47 47 0,000 0,03454612 0,03947654 ! carbohydrate transport GO:0008643 47 47 0,000 0,03454612 0,03946391 ! proteasome complex GO:0000502 48 47 0,000 0,03454612 0,03945129 ! immunoglobulin mediated immune response GO:0016064 50 47 0,000 0,03454612 0,03943868 ! phosphatase regulator activity GO:0019208 51 47 0,000 0,03454612 0,03942608 ! vesicle organization GO:0016050 50 47 0,000 0,03454612 0,03941348 ! vascular process in circulatory system GO:0003018 49 47 0,000 0,03454612 0,03940089 ! cell cortex part GO:0044448 51 47 0,000 0,03454612 0,03938831 ! lipid modification GO:0030258 49 48 0,000 0,03526921 0,04019992 ! cytokine-mediated signaling pathway GO:0019221 49 48 0,000 0,03526921 0,04018709 ! morphogenesis of a branching structure GO:0001763 49 48 0,000 0,03526921 0,04017427 ! mitochondrial transport GO:0006839 49 48 0,000 0,03526921 0,04016146 ! viral reproductive process GO:0022415 52 48 0,000 0,03526921 0,04014866 ! leukocyte migration GO:0050900 49 48 0,000 0,03526921 0,04013586 ! neuromuscular process GO:0050905 49 48 0,000 0,03526921 0,04012308 ! gastrulation GO:0007369 50 48 0,000 0,03526921 0,0401103 ! detection of abiotic stimulus GO:0009582 48 48 0,000 0,03526921 0,04009753 ! heterocycle catabolic process GO:0046700 53 48 0,000 0,03526921 0,04008477 ! B cell mediated immunity GO:0019724 51 48 0,000 0,03526921 0,04007201 ! transferase activity, transferring sulfur-containing groups GO:0016782 50 49 0,000 0,0359918 0,04088 ! single-stranded DNA binding GO:0003697 49 49 0,000 0,0359918 0,040867 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 54 49 0,000 0,0359918 0,04085401 ! intrinsic to endoplasmic reticulum membrane GO:0031227 50 49 0,000 0,0359918 0,04084103 ! ribonuclease activity GO:0004540 50 49 0,000 0,0359918 0,04082806 ! positive regulation of organelle organization GO:0010638 49 49 0,000 0,0359918 0,04081509 ! water-soluble vitamin metabolic process GO:0006767 50 49 0,000 0,0359918 0,04080214 ! negative regulation of cell motion GO:0051271 51 49 0,000 0,0359918 0,04078919 ! nucleosome GO:0000786 49 49 0,000 0,0359918 0,04077625 ! kinetochore GO:0000776 50 49 0,000 0,0359918 0,04076331 ! membrane fusion GO:0006944 51 49 0,000 0,0359918 0,04075039 ! endocrine system development GO:0035270 49 49 0,000 0,0359918 0,04073747 ! glycosaminoglycan metabolic process GO:0030203 53 50 0,000 0,03671391 0,04154162 ! regulation of actin polymerization or depolymerization GO:0008064 51 50 0,000 0,03671391 0,04152846 ! basement membrane GO:0005604 51 50 0,000 0,03671391 0,04151531 ! regulation of intracellular transport GO:0032386 52 50 0,000 0,03671391 0,04150217 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,03671391 0,04148904 ! maintenance of location GO:0051235 51 50 0,000 0,03671391 0,04147591 ! nuclear periphery GO:0034399 53 50 0,000 0,03671391 0,0414628 ! cell redox homeostasis GO:0045454 51 50 0,000 0,03671391 0,04144969 ! integrin binding GO:0005178 53 50 0,000 0,03671391 0,04143659 ! regulation of DNA replication GO:0006275 56 50 0,000 0,03671391 0,04142349 ! amino acid activation GO:0043038 50 50 0,000 0,03671391 0,04141041 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! establishment of organelle localization GO:0051656 53 50 0,000 0,03671391 0,04139733 ! regulation of bone remodeling GO:0046850 55 51 0,000 0,03743552 0,04219768 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 52 51 0,000 0,03743552 0,04218436 ! late endosome GO:0005770 51 51 0,000 0,03743552 0,04217105 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 56 51 0,000 0,03743552 0,04215775 ! ligase activity, forming carbon-oxygen bonds GO:0016875 51 51 0,000 0,03743552 0,04214446 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! negative regulation of response to stimulus GO:0048585 55 51 0,000 0,03743552 0,04213118 ! carbon-oxygen lyase activity GO:0016835 54 51 0,000 0,03743552 0,04211791 ! skeletal muscle fiber development GO:0048741 54 51 0,000 0,03743552 0,04210464 ! lipoprotein biosynthetic process GO:0042158 54 51 0,000 0,03743552 0,04209138 ! heart morphogenesis GO:0003007 54 51 0,000 0,03743552 0,04207814 ! steroid hormone receptor activity GO:0003707 53 51 0,000 0,03743552 0,04206489 ! antiporter activity GO:0015297 52 51 0,000 0,03743552 0,04205166 ! respiratory electron transport chain GO:0022904 52 52 0,000 0,03815664 0,04284823 ! positive regulation of cell migration GO:0030335 55 52 0,000 0,03815664 0,04283476 ! Golgi-associated vesicle GO:0005798 55 52 0,000 0,03815664 0,04282129 ! sphingolipid metabolic process GO:0006665 53 52 0,000 0,03815664 0,04280784 ! cell maturation GO:0048469 55 52 0,000 0,03815664 0,0427944 ! regulation of protein polymerization GO:0032271 53 52 0,000 0,03815664 0,04278096 ! regulation of actin filament length GO:0030832 53 52 0,000 0,03815664 0,04276753 ! regulation of cell projection organization GO:0031344 55 52 0,000 0,03815664 0,04275411 ! chloride transport GO:0006821 53 52 0,000 0,03815664 0,0427407 ! positive regulation of caspase activity GO:0043280 55 52 0,000 0,03815664 0,0427273 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 55 52 0,000 0,03815664 0,0427139 ! regulation of muscle contraction GO:0006937 56 52 0,000 0,03815664 0,04270052 ! negative regulation of cytoskeleton organization GO:0051494 57 52 0,000 0,03815664 0,04268714 ! glucose catabolic process GO:0006007 52 52 0,000 0,03815664 0,04267377 ! generation of a signal involved in cell-cell signaling GO:0003001 54 52 0,000 0,03815664 0,04266041 ! small ribosomal subunit GO:0015935 52 52 0,000 0,03815664 0,04264706 ! cytokine receptor activity GO:0004896 53 52 0,000 0,03815664 0,04263372 ! activation of phospholipase C activity GO:0007202 55 53 0,000 0,03887727 0,04342531 GO:0010863|positive regulation of phospholipase C activity, ! nucleoside monophosphate metabolic process GO:0009123 58 53 0,000 0,03887727 0,04341173 ! nucleoside metabolic process GO:0009116 61 53 0,000 0,03887727 0,04339816 ! N-acetyltransferase activity GO:0008080 54 53 0,000 0,03887727 0,0433846 ! synaptic vesicle GO:0008021 57 53 0,000 0,03887727 0,04337105 ! pyridoxal phosphate binding GO:0030170 56 53 0,000 0,03887727 0,0433575 GO:0070279|vitamin B6 binding, ! viral reproduction GO:0016032 57 53 0,000 0,03887727 0,04334397 ! cell projection assembly GO:0030031 56 53 0,000 0,03887727 0,04333044 ! proton transport GO:0015992 53 53 0,000 0,03887727 0,04331692 ! mRNA binding GO:0003729 55 53 0,000 0,03887727 0,04330341 ! single fertilization GO:0007338 55 53 0,000 0,03887727 0,0432899 ! axon GO:0030424 58 54 0,000 0,03959741 0,04407804 ! heat shock protein binding GO:0031072 54 54 0,000 0,03959741 0,0440643 ! regulation of neurotransmitter levels GO:0001505 60 54 0,000 0,03959741 0,04405057 ! double-stranded DNA binding GO:0003690 55 54 0,000 0,03959741 0,04403685 ! positive regulation of phospholipase activity GO:0010518 56 54 0,000 0,03959741 0,04402314 ! tRNA processing GO:0008033 55 54 0,000 0,03959741 0,04400944 ! regulation of cellular response to stress GO:0080135 57 54 0,000 0,03959741 0,04399575 ! growth factor receptor binding GO:0070851 56 54 0,000 0,03959741 0,04398206 ! regulation of protein catabolic process GO:0042176 57 54 0,000 0,03959741 0,04396839 ! regulation of tissue remodeling GO:0034103 58 54 0,000 0,03959741 0,04395472 ! regulation of cellular component size GO:0032535 56 55 0,000 0,04031705 0,04473965 ! hydrogen transport GO:0006818 55 55 0,000 0,04031705 0,04472575 ! glycerophospholipid biosynthetic process GO:0046474 59 55 0,000 0,04031705 0,04471186 ! large ribosomal subunit GO:0015934 56 55 0,000 0,04031705 0,04469798 ! protein amino acid autophosphorylation GO:0046777 57 55 0,000 0,04031705 0,04468411 ! positive regulation of secretion GO:0051047 60 56 0,000 0,04103621 0,04546705 ! regulation of mitosis GO:0007088 56 56 0,000 0,04103621 0,04545295 GO:0051783|regulation of nuclear division, ! actin filament organization GO:0007015 59 56 0,000 0,04103621 0,04543886 ! regulation of phospholipase activity GO:0010517 58 56 0,000 0,04103621 0,04542477 ! coenzyme biosynthetic process GO:0009108 59 56 0,000 0,04103621 0,04541069 ! cellular amino acid catabolic process GO:0009063 59 56 0,000 0,04103621 0,04539663 ! cartilage development GO:0051216 59 56 0,000 0,04103621 0,04538257 ! regulation of protein complex assembly GO:0043254 57 56 0,000 0,04103621 0,04536852 ! receptor signaling protein serine/threonine kinase activity GO:0004702 58 56 0,000 0,04103621 0,04535448 ! mesoderm development GO:0007498 57 56 0,000 0,04103621 0,04534044 ! camera-type eye development GO:0043010 59 56 0,000 0,04103621 0,04532642 ! regulation of transcription factor activity GO:0051090 59 57 0,000 0,04175488 0,04610596 GO:0090046|regulation of transcription regulator activity, ! chromosome segregation GO:0007059 59 57 0,000 0,04175488 0,04609171 ! positive regulation of T cell activation GO:0050870 62 57 0,000 0,04175488 0,04607746 ! positive regulation of lipase activity GO:0060193 59 57 0,000 0,04175488 0,04606323 ! integrin-mediated signaling pathway GO:0007229 61 57 0,000 0,04175488 0,046049 ! adult behavior GO:0030534 60 57 0,000 0,04175488 0,04603479 ! myosin complex GO:0016459 59 57 0,000 0,04175488 0,04602058 ! regulation of angiogenesis GO:0045765 60 58 0,000 0,04247306 0,04679768 ! lysosomal membrane GO:0005765 59 58 0,000 0,04247306 0,04678325 ! extracellular matrix organization GO:0030198 59 58 0,000 0,04247306 0,04676882 ! positive regulation of cell motion GO:0051272 61 58 0,000 0,04247306 0,0467544 ! regulation of vesicle-mediated transport GO:0060627 60 58 0,000 0,04247306 0,04674 ! detection of external stimulus GO:0009581 59 58 0,000 0,04247306 0,0467256 ! secondary metabolic process GO:0019748 59 58 0,000 0,04247306 0,04671121 ! translation initiation factor activity GO:0003743 58 58 0,000 0,04247306 0,04669682 ! dendrite GO:0030425 61 59 0,000 0,04319074 0,04747127 ! molecular adaptor activity GO:0060090 65 59 0,000 0,04319074 0,04745666 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 60 59 0,000 0,04319074 0,04744206 GO:0051213|dioxygenase activity, ! embryonic limb morphogenesis GO:0030326 63 59 0,000 0,04319074 0,04742748 GO:0035113|embryonic appendage morphogenesis, ! ubiquitin thiolesterase activity GO:0004221 62 59 0,000 0,04319074 0,0474129 ! regulation of heart contraction GO:0008016 62 59 0,000 0,04319074 0,04739833 ! copper ion binding GO:0005507 61 59 0,000 0,04319074 0,04738376 ! activation of immune response GO:0002253 68 59 0,000 0,04319074 0,04736921 ! aminoglycan metabolic process GO:0006022 62 59 0,000 0,04319074 0,04735467 ! amine transmembrane transporter activity GO:0005275 59 59 0,000 0,04319074 0,04734013 ! chromatin remodeling complex GO:0016585 61 59 0,000 0,04319074 0,04732561 ! cell soma GO:0043025 63 59 0,000 0,04319074 0,04731109 ! regulation of homeostatic process GO:0032844 68 59 0,000 0,04319074 0,04729658 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 61 60 0,000 0,04390794 0,04806722 ! multicellular organism reproduction GO:0032504 62 60 0,000 0,04390794 0,04805249 GO:0048609|reproductive process in a multicellular organism, ! occluding junction GO:0070160 60 60 0,000 0,04390794 0,04803777 GO:0005923|tight junction, ! regulation of lipid metabolic process GO:0019216 63 60 0,000 0,04390794 0,04802305 ! myeloid cell differentiation GO:0030099 64 60 0,000 0,04390794 0,04800835 ! oxygen and reactive oxygen species metabolic process GO:0006800 60 60 0,000 0,04390794 0,04799365 ! regulation of cytokine biosynthetic process GO:0042035 63 60 0,000 0,04390794 0,04797897 ! lymphocyte mediated immunity GO:0002449 63 60 0,000 0,04390794 0,04796429 ! chloride channel activity GO:0005254 61 60 0,000 0,04390794 0,04794962 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 62 61 0,000 0,04462466 0,04871741 ! cell cycle checkpoint GO:0000075 64 61 0,000 0,04462466 0,04870252 ! fertilization GO:0009566 64 61 0,000 0,04462466 0,04868764 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 65 61 0,000 0,04462466 0,04867277 ! gonad development GO:0008406 61 61 0,000 0,04462466 0,04865791 ! protein maturation by peptide bond cleavage GO:0051605 64 61 0,000 0,04462466 0,04864305 ! regulation of immune effector process GO:0002697 65 61 0,000 0,04462466 0,04862821 ! amine catabolic process GO:0009310 68 62 0,000 0,04534088 0,04939362 ! phosphoinositide metabolic process GO:0030384 66 62 0,000 0,04534088 0,04937855 ! glycerolipid biosynthetic process GO:0045017 66 62 0,000 0,04534088 0,0493635 ! coated membrane GO:0048475 67 62 0,000 0,04534088 0,04934845 GO:0030117|membrane coat, ! hexose catabolic process GO:0019320 63 62 0,000 0,04534088 0,04933342 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 63 62 0,000 0,04534088 0,04931839 ! extracellular ligand-gated ion channel activity GO:0005230 67 62 0,000 0,04534088 0,04930337 ! germ cell development GO:0007281 62 62 0,000 0,04534088 0,04928836 ! ligand-dependent nuclear receptor activity GO:0004879 65 62 0,000 0,04534088 0,04927336 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 70 63 0,000 0,04605661 0,05003595 ! mitochondrial respiratory chain GO:0005746 65 63 0,000 0,04605661 0,05002073 ! negative regulation of ligase activity GO:0051352 64 63 0,000 0,04605661 0,05000552 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein oligomerization GO:0051259 64 63 0,000 0,04605661 0,04999032 ! transition metal ion transport GO:0000041 65 63 0,000 0,04605661 0,04997513 ! appendage morphogenesis GO:0035107 67 63 0,000 0,04605661 0,04995995 GO:0035108|limb morphogenesis, ! activation of MAPK activity GO:0000187 69 63 0,000 0,04605661 0,04994478 ! cellular defense response GO:0006968 64 63 0,000 0,04605661 0,04992962 ! B cell activation GO:0042113 66 63 0,000 0,04605661 0,04991446 ! antigen processing and presentation GO:0019882 64 63 0,000 0,04605661 0,04989932 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 65 63 0,000 0,04605661 0,04988419 ! microtubule motor activity GO:0003777 67 63 0,000 0,04605661 0,04986906 ! organelle localization GO:0051640 66 63 0,000 0,04605661 0,04985394 ! transforming growth factor beta receptor signaling pathway GO:0007179 67 64 0,000 0,04677186 0,05061282 ! lung development GO:0030324 65 64 0,000 0,04677186 0,05059749 ! respiratory chain GO:0070469 66 64 0,000 0,04677186 0,05058216 ! developmental maturation GO:0021700 67 64 0,000 0,04677186 0,05056685 ! amino acid transport GO:0006865 64 64 0,000 0,04677186 0,05055154 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 66 64 0,000 0,04677186 0,05053625 ! anion channel activity GO:0005253 65 64 0,000 0,04677186 0,05052096 ! cellular hormone metabolic process GO:0034754 65 65 0,000 0,04748662 0,0512775 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 65 0,000 0,04748662 0,051262 ! nuclear pore GO:0005643 69 65 0,000 0,04748662 0,05124651 ! regulation of MAPKKK cascade GO:0043408 72 65 0,000 0,04748662 0,05123103 ! rhythmic process GO:0048511 66 65 0,000 0,04748662 0,05121556 ! regulation of lipase activity GO:0060191 67 65 0,000 0,04748662 0,05120009 ! adaptive immune response GO:0002250 68 65 0,000 0,04748662 0,05118464 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! appendage development GO:0048736 69 65 0,000 0,04748662 0,05116919 GO:0060173|limb development, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 67 65 0,000 0,04748662 0,05115376 ! lipoprotein metabolic process GO:0042157 68 65 0,000 0,04748662 0,05113833 ! DNA-dependent DNA replication GO:0006261 66 65 0,000 0,04748662 0,05112291 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 71 66 0,000 0,04820089 0,05187624 ! endoplasmic reticulum lumen GO:0005788 66 66 0,000 0,04820089 0,05186061 ! response to steroid hormone stimulus GO:0048545 69 66 0,000 0,04820089 0,05184499 ! diacylglycerol binding GO:0019992 71 66 0,000 0,04820089 0,05182938 ! amine binding GO:0043176 70 66 0,000 0,04820089 0,05181378 ! response to nutrient GO:0007584 67 66 0,000 0,04820089 0,05179819 ! acetyltransferase activity GO:0016407 68 66 0,000 0,04820089 0,0517826 ! respiratory tube development GO:0030323 68 67 0,000 0,04891467 0,05253362 ! mRNA transport GO:0051028 70 67 0,000 0,04891467 0,05251783 ! intracellular protein transmembrane transport GO:0065002 70 67 0,000 0,04891467 0,05250204 ! tubulin binding GO:0015631 70 67 0,000 0,04891467 0,05248627 ! activation of protein kinase activity GO:0032147 70 67 0,000 0,04891467 0,0524705 ! Ras GTPase binding GO:0017016 70 67 0,000 0,04891467 0,05245474 ! humoral immune response GO:0006959 70 67 0,000 0,04891467 0,052439 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 69 67 0,000 0,04891467 0,05242326 ! ubiquitin ligase complex GO:0000151 71 67 0,000 0,04891467 0,05240753 ! nucleosome assembly GO:0006334 69 67 0,000 0,04891467 0,05239181 ! muscle cell differentiation GO:0042692 68 68 0,000 0,04962797 0,05313987 ! fatty acid biosynthetic process GO:0006633 70 68 0,000 0,04962797 0,05312395 ! lymphocyte differentiation GO:0030098 75 68 0,000 0,04962797 0,05310803 ! protein-DNA complex GO:0032993 69 68 0,000 0,04962797 0,05309212 ! learning or memory GO:0007611 72 68 0,000 0,04962797 0,05307621 ! chloride ion binding GO:0031404 70 68 0,000 0,04962797 0,05306032 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 71 68 0,000 0,04962797 0,05304444 ! chromatin assembly GO:0031497 70 68 0,000 0,04962797 0,05302857 ! leukocyte mediated immunity GO:0002443 71 68 0,000 0,04962797 0,05301271 ! extrinsic to membrane GO:0019898 68 68 0,000 0,04962797 0,05299685 ! calcium channel activity GO:0005262 73 68 0,000 0,04962797 0,05298101 ! ribonucleoprotein complex assembly GO:0022618 69 68 0,000 0,04962797 0,05296518 ! respiratory system development GO:0060541 69 68 0,000 0,04962797 0,05294935 ! N-acyltransferase activity GO:0016410 69 68 0,000 0,04962797 0,05293354 ! eye development GO:0001654 74 69 0,000 0,05034078 0,05367779 ! positive regulation of ligase activity GO:0051351 71 69 0,000 0,05034078 0,05366177 ! sarcomere GO:0030017 75 69 0,000 0,05034078 0,05364576 ! cAMP-mediated signaling GO:0019933 72 69 0,000 0,05034078 0,05362975 ! axon guidance GO:0007411 74 69 0,000 0,05034078 0,05361376 ! focal adhesion GO:0005925 75 69 0,000 0,05034078 0,05359777 ! regulation of DNA binding GO:0051101 72 70 0,000 0,05105311 0,05433998 ! carboxylic acid transmembrane transporter activity GO:0046943 71 70 0,000 0,05105311 0,05432379 ! early endosome GO:0005769 79 70 0,000 0,05105311 0,05430761 ! response to hypoxia GO:0001666 76 70 0,000 0,05105311 0,05429144 ! female pregnancy GO:0007565 71 70 0,000 0,05105311 0,05427527 ! rRNA processing GO:0006364 70 70 0,000 0,05105311 0,05425912 ! cytosolic ribosome GO:0022626 70 70 0,000 0,05105311 0,05424298 ! cell-matrix adhesion GO:0007160 76 71 0,000 0,05176495 0,05498293 ! FAD binding GO:0050660 72 71 0,000 0,05176495 0,05496658 ! response to oxygen levels GO:0070482 77 71 0,000 0,05176495 0,05495024 ! mitochondrial outer membrane GO:0005741 75 71 0,000 0,05176495 0,05493391 ! defense response to bacterium GO:0042742 71 71 0,000 0,05176495 0,05491759 ! steroid biosynthetic process GO:0006694 72 71 0,000 0,05176495 0,05490128 ! monosaccharide catabolic process GO:0046365 72 71 0,000 0,05176495 0,05488498 ! regulation of synaptic transmission GO:0050804 73 71 0,000 0,05176495 0,05486869 ! reproductive structure development GO:0048608 71 71 0,000 0,05176495 0,05485241 ! neurotransmitter transport GO:0006836 73 71 0,000 0,05176495 0,05483614 ! organic acid transmembrane transporter activity GO:0005342 72 71 0,000 0,05176495 0,05481988 ! phospholipase activity GO:0004620 75 71 0,000 0,05176495 0,05480362 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 75 71 0,000 0,05176495 0,05478738 ! cell projection part GO:0044463 75 71 0,000 0,05176495 0,05477115 ! amine biosynthetic process GO:0009309 75 72 0,000 0,0524763 0,05550737 ! meiosis GO:0007126 73 72 0,000 0,0524763 0,05549093 GO:0051327|M phase of meiotic cell cycle, ! elevation of cytosolic calcium ion concentration GO:0007204 77 72 0,000 0,0524763 0,0554745 ! acute inflammatory response GO:0002526 76 72 0,000 0,0524763 0,05545808 ! cholesterol metabolic process GO:0008203 74 72 0,000 0,0524763 0,05544168 ! lipid transporter activity GO:0005319 77 72 0,000 0,0524763 0,05542528 ! regulation of ubiquitin-protein ligase activity GO:0051438 74 72 0,000 0,0524763 0,05540889 ! cell-substrate adherens junction GO:0005924 78 72 0,000 0,0524763 0,05539251 ! negative regulation of transport GO:0051051 74 73 0,000 0,05318717 0,05612629 ! vacuolar membrane GO:0005774 74 73 0,000 0,05318717 0,05610971 ! rRNA metabolic process GO:0016072 73 73 0,000 0,05318717 0,05609314 ! meiotic cell cycle GO:0051321 75 73 0,000 0,05318717 0,05607658 ! negative regulation of organelle organization GO:0010639 78 73 0,000 0,05318717 0,05606003 ! regulation of protein transport GO:0051223 77 73 0,000 0,05318717 0,05604349 GO:0070201|regulation of establishment of protein localization, ! exopeptidase activity GO:0008238 78 73 0,000 0,05318717 0,05602696 ! cytosolic calcium ion homeostasis GO:0051480 78 73 0,000 0,05318717 0,05601043 ! nucleosome organization GO:0034728 76 74 0,000 0,05389755 0,05674179 ! neuropeptide signaling pathway GO:0007218 79 74 0,000 0,05389755 0,05672507 ! pore complex GO:0046930 78 74 0,000 0,05389755 0,05670836 ! myofibril GO:0030016 80 74 0,000 0,05389755 0,05669165 ! regulation of blood pressure GO:0008217 76 74 0,000 0,05389755 0,05667496 ! apical junction complex GO:0043296 74 74 0,000 0,05389755 0,05665828 ! cellular carbohydrate catabolic process GO:0044275 75 74 0,000 0,05389755 0,0566416 ! development of primary sexual characteristics GO:0045137 74 74 0,000 0,05389755 0,05662494 ! membrane raft GO:0045121 78 74 0,000 0,05389755 0,05660828 ! cellular response to hormone stimulus GO:0032870 81 74 0,000 0,05389755 0,05659164 ! serine-type endopeptidase inhibitor activity GO:0004867 75 74 0,000 0,05389755 0,056575 ! nuclear chromosome part GO:0044454 76 74 0,000 0,05389755 0,05655838 ! response to drug GO:0042493 77 75 0,000 0,05460745 0,05728649 ! small GTPase binding GO:0031267 78 75 0,000 0,05460745 0,05726967 ! regulation of catabolic process GO:0009894 80 75 0,000 0,05460745 0,05725285 ! cell-substrate junction GO:0030055 82 75 0,000 0,05460745 0,05723605 ! membrane lipid biosynthetic process GO:0046467 77 75 0,000 0,05460745 0,05721925 ! phosphoinositide-mediated signaling GO:0048015 79 75 0,000 0,05460745 0,05720247 ! tube morphogenesis GO:0035239 79 75 0,000 0,05460745 0,05718569 ! cellular lipid catabolic process GO:0044242 77 75 0,000 0,05460745 0,05716893 ! cysteine-type endopeptidase activity GO:0004197 75 75 0,000 0,05460745 0,05715217 ! structural constituent of cytoskeleton GO:0005200 81 75 0,000 0,05460745 0,05713543 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 80 76 0,000 0,05531687 0,05786073 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 76 76 0,000 0,05531687 0,05784379 ! regulation of ligase activity GO:0051340 78 76 0,000 0,05531687 0,05782685 ! vitamin metabolic process GO:0006766 77 76 0,000 0,05531687 0,05780993 ! inorganic anion transport GO:0015698 78 76 0,000 0,05531687 0,05779302 ! chromosome, centromeric region GO:0000775 78 76 0,000 0,05531687 0,05777611 ! apicolateral plasma membrane GO:0016327 76 76 0,000 0,05531687 0,05775922 ! T cell activation GO:0042110 82 76 0,000 0,05531687 0,05774234 ! digestion GO:0007586 80 76 0,000 0,05531687 0,05772546 ! cell-substrate adhesion GO:0031589 81 76 0,000 0,05531687 0,0577086 ! cilium GO:0005929 77 76 0,000 0,05531687 0,05769175 ! contractile fiber part GO:0044449 82 76 0,000 0,05531687 0,0576749 ! regulation of adenylate cyclase activity GO:0045761 80 77 0,000 0,0560258 0,058397 ! nuclear speck GO:0016607 80 77 0,000 0,0560258 0,05837996 ! G-protein-coupled receptor binding GO:0001664 78 77 0,000 0,0560258 0,05836293 ! endonuclease activity GO:0004519 80 77 0,000 0,0560258 0,05834591 ! regulation of transmission of nerve impulse GO:0051969 79 77 0,000 0,0560258 0,0583289 ! hydrogen ion transmembrane transporter activity GO:0015078 78 77 0,000 0,0560258 0,0583119 ! extracellular matrix structural constituent GO:0005201 80 77 0,000 0,0560258 0,05829491 ! vacuolar part GO:0044437 78 77 0,000 0,0560258 0,05827793 ! thiolester hydrolase activity GO:0016790 81 78 0,000 0,05673425 0,05899767 ! potassium channel complex GO:0034705 81 78 0,000 0,05673425 0,05898049 GO:0008076|voltage-gated potassium channel complex, ! cofactor biosynthetic process GO:0051188 81 78 0,000 0,05673425 0,05896333 ! blood coagulation GO:0007596 81 78 0,000 0,05673425 0,05894617 GO:0050817|coagulation, ! phospholipid biosynthetic process GO:0008654 83 79 0,000 0,05744221 0,05966438 ! biogenic amine metabolic process GO:0006576 85 79 0,000 0,05744221 0,05964703 ! phosphoric diester hydrolase activity GO:0008081 82 79 0,000 0,05744221 0,05962969 ! positive regulation of MAP kinase activity GO:0043406 85 79 0,000 0,05744221 0,05961236 ! regulation of cyclase activity GO:0031279 82 79 0,000 0,05744221 0,05959504 ! regulation of neuron differentiation GO:0045664 82 79 0,000 0,05744221 0,05957773 ! regulation of T cell activation GO:0050863 84 79 0,000 0,05744221 0,05956043 ! regulation of cAMP biosynthetic process GO:0030817 82 79 0,000 0,05744221 0,05954315 ! exocytosis GO:0006887 81 79 0,000 0,05744221 0,05952587 ! nitrogen compound catabolic process GO:0044270 89 79 0,000 0,05744221 0,0595086 ! regulation of protein localization GO:0032880 83 79 0,000 0,05744221 0,05949134 ! regulation of DNA metabolic process GO:0051052 90 80 0,000 0,05814969 0,0602066 ! alcohol catabolic process GO:0046164 83 80 0,000 0,05814969 0,06018915 ! GTPase binding GO:0051020 83 80 0,000 0,05814969 0,0601717 ! regulation of cell cycle process GO:0010564 84 80 0,000 0,05814969 0,06015427 ! regulation of lyase activity GO:0051339 83 80 0,000 0,05814969 0,06013685 ! ATP biosynthetic process GO:0006754 85 80 0,000 0,05814969 0,06011944 ! one-carbon metabolic process GO:0006730 87 80 0,000 0,05814969 0,06010204 ! monooxygenase activity GO:0004497 82 80 0,000 0,05814969 0,06008465 ! condensed chromosome GO:0000793 82 80 0,000 0,05814969 0,06006727 ! contractile fiber GO:0043292 86 80 0,000 0,05814969 0,0600499 ! protein ubiquitination GO:0016567 86 80 0,000 0,05814969 0,06003254 ! ossification GO:0001503 85 81 0,000 0,05885669 0,06074487 ! cellular carbohydrate biosynthetic process GO:0034637 83 81 0,000 0,05885669 0,06072732 ! sterol metabolic process GO:0016125 83 81 0,000 0,05885669 0,06070978 ! regulation of cAMP metabolic process GO:0030814 84 81 0,000 0,05885669 0,06069224 ! protein binding, bridging GO:0030674 86 81 0,000 0,05885669 0,06067472 ! regulation of neurological system process GO:0031644 83 81 0,000 0,05885669 0,06065721 ! protein transporter activity GO:0008565 85 82 0,000 0,05956321 0,06136763 ! positive regulation of immune response GO:0050778 91 82 0,000 0,05956321 0,06134993 ! regulation of defense response GO:0031347 82 82 0,000 0,05956321 0,06133224 ! bone development GO:0060348 86 82 0,000 0,05956321 0,06131456 ! carboxylesterase activity GO:0004091 86 82 0,000 0,05956321 0,06129689 ! organelle outer membrane GO:0031968 87 83 0,000 0,06026924 0,06200561 ! SH3 domain binding GO:0017124 97 83 0,000 0,06026924 0,06198775 ! hemostasis GO:0007599 86 83 0,000 0,06026924 0,0619699 ! oxidative phosphorylation GO:0006119 83 83 0,000 0,06026924 0,06195206 ! heparin binding GO:0008201 90 83 0,000 0,06026924 0,06193423 ! amine transport GO:0015837 83 83 0,000 0,06026924 0,06191641 ! extracellular matrix part GO:0044420 85 83 0,000 0,06026924 0,06189861 ! phosphoinositide binding GO:0035091 90 83 0,000 0,06026924 0,06188081 ! regulation of nucleotide biosynthetic process GO:0030808 87 84 0,000 0,06097479 0,06258723 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 85 84 0,000 0,06097479 0,06256925 GO:0010498|proteasomal protein catabolic process, ! Ras GTPase activator activity GO:0005099 89 84 0,000 0,06097479 0,06255127 ! regulation of membrane potential GO:0042391 92 84 0,000 0,06097479 0,06253331 ! perinuclear region of cytoplasm GO:0048471 91 85 0,000 0,06167986 0,06323824 ! cellular respiration GO:0045333 85 85 0,000 0,06167986 0,06322009 ! transmembrane receptor protein kinase activity GO:0019199 88 85 0,000 0,06167986 0,06320195 ! outer membrane GO:0019867 89 85 0,000 0,06167986 0,06318382 ! DNA recombination GO:0006310 86 85 0,000 0,06167986 0,0631657 ! neurotransmitter receptor activity GO:0030594 86 85 0,000 0,06167986 0,06314759 ! leukocyte differentiation GO:0002521 95 86 0,000 0,06238445 0,06385064 ! Golgi vesicle transport GO:0048193 86 86 0,000 0,06238445 0,06383234 ! pigment granule GO:0048770 90 86 0,000 0,06238445 0,06381406 GO:0042470|melanosome, ! neurotransmitter binding GO:0042165 88 86 0,000 0,06238445 0,06379578 ! anion binding GO:0043168 89 86 0,000 0,06238445 0,06377752 ! sex differentiation GO:0007548 86 86 0,000 0,06238445 0,06375927 ! UDP-glycosyltransferase activity GO:0008194 91 86 0,000 0,06238445 0,06374102 ! spindle GO:0005819 89 87 0,000 0,06308856 0,064442 ! microtubule cytoskeleton organization GO:0000226 92 87 0,000 0,06308856 0,06442358 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 93 87 0,000 0,06308856 0,06440516 ! regulation of cyclic nucleotide metabolic process GO:0030799 90 87 0,000 0,06308856 0,06438675 ! protein processing GO:0016485 92 87 0,000 0,06308856 0,06436836 ! ATP-dependent helicase activity GO:0008026 92 88 0,000 0,06379219 0,06506766 GO:0070035|purine NTP-dependent helicase activity, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 89 88 0,000 0,06379219 0,06504908 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 89 88 0,000 0,06379219 0,06503052 ! skeletal muscle tissue development GO:0007519 92 88 0,000 0,06379219 0,06501196 GO:0060538|skeletal muscle organ development, ! lipase activity GO:0016298 92 88 0,000 0,06379219 0,06499341 ! detection of stimulus GO:0051606 90 88 0,000 0,06379219 0,06497487 ! carboxylic acid catabolic process GO:0046395 93 89 0,000 0,06449533 0,06567232 GO:0016054|organic acid catabolic process, ! sulfur metabolic process GO:0006790 90 89 0,000 0,06449533 0,0656536 ! negative regulation of multicellular organismal process GO:0051241 93 89 0,000 0,06449533 0,06563489 ! regulation of binding GO:0051098 93 90 0,000 0,065198 0,06633107 ! intermediate filament GO:0005882 92 90 0,000 0,065198 0,06631218 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 95 90 0,000 0,065198 0,0662933 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! nuclear membrane GO:0031965 92 90 0,000 0,065198 0,06627442 ! external side of plasma membrane GO:0009897 99 90 0,000 0,065198 0,06625556 ! growth factor binding GO:0019838 92 90 0,000 0,065198 0,06623672 ! regulation of nucleotide metabolic process GO:0006140 93 90 0,000 0,065198 0,06621788 ! adherens junction GO:0005912 96 90 0,000 0,065198 0,06619905 ! ATP metabolic process GO:0046034 96 91 0,000 0,06590019 0,066893 ! homophilic cell adhesion GO:0007156 93 91 0,000 0,06590019 0,06687399 ! ribonucleoside triphosphate biosynthetic process GO:0009201 97 91 0,000 0,06590019 0,06685499 ! protein modification by small protein conjugation GO:0032446 98 91 0,000 0,06590019 0,066836 ! forebrain development GO:0030900 95 91 0,000 0,06590019 0,06681703 ! carbohydrate biosynthetic process GO:0016051 93 91 0,000 0,06590019 0,06679806 ! apical plasma membrane GO:0016324 96 91 0,000 0,06590019 0,0667791 ! intermediate filament cytoskeleton GO:0045111 93 91 0,000 0,06590019 0,06676016 ! structure-specific DNA binding GO:0043566 93 92 0,000 0,06660189 0,06745189 ! angiogenesis GO:0001525 95 92 0,000 0,06660189 0,06743276 ! glycerophospholipid metabolic process GO:0006650 98 92 0,000 0,06660189 0,06741365 ! nucleoside triphosphate biosynthetic process GO:0009142 98 92 0,000 0,06660189 0,06739455 ! clathrin-coated vesicle GO:0030136 100 92 0,000 0,06660189 0,06737546 ! gland development GO:0048732 95 92 0,000 0,06660189 0,06735637 ! DNA packaging GO:0006323 94 92 0,000 0,06660189 0,0673373 ! anatomical structure homeostasis GO:0060249 96 93 0,000 0,06730312 0,06802701 ! receptor complex GO:0043235 97 93 0,000 0,06730312 0,06800777 ! voltage-gated potassium channel activity GO:0005249 99 93 0,000 0,06730312 0,06798853 ! hormone metabolic process GO:0042445 96 93 0,000 0,06730312 0,0679693 ! translational elongation GO:0006414 97 94 0,000 0,06800387 0,06865757 ! nucleotidyltransferase activity GO:0016779 96 94 0,000 0,06800387 0,06863816 ! metalloendopeptidase activity GO:0004222 105 94 0,000 0,06800387 0,06861877 ! carbohydrate catabolic process GO:0016052 95 94 0,000 0,06800387 0,06859938 ! protein maturation GO:0051604 99 94 0,000 0,06800387 0,06858001 ! solute:cation symporter activity GO:0015294 95 94 0,000 0,06800387 0,06856065 ! carboxylic acid binding GO:0031406 99 95 0,000 0,06870414 0,0692471 ! regulation of response to external stimulus GO:0032101 97 95 0,000 0,06870414 0,06922756 ! response to virus GO:0009615 102 95 0,000 0,06870414 0,06920803 ! peroxisome GO:0005777 97 96 0,000 0,06940393 0,06989324 GO:0042579|microbody, ! integral to organelle membrane GO:0031301 96 96 0,000 0,06940393 0,06987354 ! Wnt receptor signaling pathway GO:0016055 104 96 0,000 0,06940393 0,06985384 ! translation factor activity, nucleic acid binding GO:0008135 99 96 0,000 0,06940393 0,06983416 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 97 96 0,000 0,06940393 0,06981449 ! cell fate commitment GO:0045165 98 96 0,000 0,06940393 0,06979483 ! response to nutrient levels GO:0031667 98 96 0,000 0,06940393 0,06977518 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 101 97 0,000 0,07010325 0,0704584 ! microtubule associated complex GO:0005875 104 97 0,000 0,07010325 0,07043857 ! peptidyl-amino acid modification GO:0018193 99 97 0,000 0,07010325 0,07041876 ! anchoring junction GO:0070161 103 97 0,000 0,07010325 0,07039896 ! reproductive developmental process GO:0003006 97 97 0,000 0,07010325 0,07037917 ! unfolded protein binding GO:0051082 100 98 0,000 0,07080208 0,07106077 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 99 98 0,000 0,07080208 0,07104081 ! polysaccharide metabolic process GO:0005976 102 98 0,000 0,07080208 0,07102085 ! protein modification by small protein conjugation or removal GO:0070647 105 98 0,000 0,07080208 0,07100091 ! chromatin binding GO:0003682 102 99 0,000 0,07150044 0,0716811 ! nuclear chromosome GO:0000228 102 99 0,000 0,07150044 0,07166098 ! anterior/posterior pattern formation GO:0009952 102 99 0,000 0,07150044 0,07164087 ! Ras protein signal transduction GO:0007265 105 99 0,000 0,07150044 0,07162078 ! electron transport chain GO:0022900 102 100 0,000 0,07219832 0,07229955 ! tRNA metabolic process GO:0006399 101 100 0,000 0,07219832 0,07227928 ! protein polymerization GO:0051258 114 100 0,000 0,07219832 0,07225903 ! cytokine binding GO:0019955 101 100 0,000 0,07219832 0,07223878 ! regulation of cell morphogenesis GO:0022604 104 100 0,000 0,07219832 0,07221855 ! chromatin assembly or disassembly GO:0006333 104 100 0,000 0,07219832 0,07219832