pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-pos-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/93-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 2,000 9,744E-08 2,381E-04 ! steroid hormone receptor signaling pathway GO:0030518 146 66 4,000 3,37E-07 4,117E-04 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 4,000 4,869E-07 3,965E-04 ! neuroblast proliferation GO:0007405 25 11 2,000 1,593E-06 9,728E-04 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 2,000 3,497E-06 1,709E-03 GO:0060675|ureteric bud morphogenesis, ! estrogen receptor signaling pathway GO:0030520 45 20 2,000 1,085E-05 4,418E-03 ! ureteric bud development GO:0001657 50 22 2,000 1,461E-05 5,1E-03 ! regulation of neuron differentiation GO:0045664 187 85 3,000 3,608E-05 0,01101721 ! Notch receptor processing GO:0007220 11 5 1,000 4,613E-05 0,01252077 ! muscle cell migration GO:0014812 8 5 1,000 4,613E-05 0,01126869 ! metanephros development GO:0001656 81 32 2,000 4,634E-05 0,01029096 ! inner ear morphogenesis GO:0042472 51 34 2,000 5,573E-05 0,01134548 ! cell fate specification GO:0001708 56 34 2,000 5,573E-05 0,01047275 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 6,909E-05 0,01205662 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 6,909E-05 0,01125285 GO:0045686|negative regulation of glial cell differentiation, ! response to exogenous dsRNA GO:0043330 13 6 1,000 6,909E-05 0,01054954 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 7,202E-05 0,01035032 ! embryonic skeletal system morphogenesis GO:0048704 68 38 2,000 7,808E-05 0,01059666 ! cytokinesis during cell cycle GO:0033205 14 7 1,000 9,659E-05 0,01241987 ! amyloid precursor protein catabolic process GO:0042987 15 7 1,000 9,659E-05 0,01179888 ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 1,000 9,659E-05 0,01123703 ! ear morphogenesis GO:0042471 64 42 2,000 1,056E-04 0,01172513 ! cytokinesis GO:0000910 84 42 2,000 1,056E-04 0,01121534 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 1,286E-04 0,01309144 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 1,286E-04 0,01256778 ! B cell receptor signaling pathway GO:0050853 22 8 1,000 1,286E-04 0,0120844 ! branching morphogenesis of a tube GO:0048754 102 45 2,000 1,299E-04 0,01175405 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,651E-04 0,01440702 ! amyloid precursor protein metabolic process GO:0042982 18 9 1,000 1,651E-04 0,01391023 ! pyrimidine base metabolic process GO:0006206 22 9 1,000 1,651E-04 0,01344655 ! morphogenesis of a branching structure GO:0001763 116 52 2,000 2,001E-04 0,01577126 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 2,061E-04 0,01573553 ! regulation of gliogenesis GO:0014013 23 10 1,000 2,061E-04 0,0152587 GO:0045685|regulation of glial cell differentiation, ! response to dsRNA GO:0043331 23 10 1,000 2,061E-04 0,01480991 ! induction of an organ GO:0001759 17 10 1,000 2,061E-04 0,01438677 ! inner ear development GO:0048839 89 53 2,000 2,118E-04 0,01437326 ! embryonic skeletal system development GO:0048706 101 54 2,000 2,239E-04 0,01478441 ! epithelial tube morphogenesis GO:0060562 114 54 2,000 2,239E-04 0,01439534 ! thyroid gland development GO:0030878 26 11 1,000 2,516E-04 0,01575819 ! thymus development GO:0048538 29 11 1,000 2,516E-04 0,01536424 ! T cell receptor signaling pathway GO:0050852 29 11 1,000 2,516E-04 0,0149895 ! hippocampus development GO:0021766 29 12 1,000 3,015E-04 0,01753446 ! developmental induction GO:0031128 22 12 1,000 3,015E-04 0,01712668 GO:0045168|cell-cell signaling involved in cell fate specification, ! kidney development GO:0001822 133 60 2,000 3,06E-04 0,01699249 ! skeletal system morphogenesis GO:0048705 118 63 2,000 3,535E-04 0,01919118 ! membrane protein proteolysis GO:0033619 33 13 1,000 3,558E-04 0,01889401 GO:0006509|membrane protein ectodomain proteolysis, ! ear development GO:0043583 114 66 2,000 4,055E-04 0,02107491 ! urogenital system development GO:0001655 149 69 2,000 4,621E-04 0,02351758 ! sulfate transport GO:0008272 27 15 1,000 4,776E-04 0,02381003 ! glycoprotein catabolic process GO:0006516 33 15 1,000 4,776E-04 0,02333383 ! nucleobase metabolic process GO:0009112 43 17 1,000 6,168E-04 0,02954713 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 1,000 6,168E-04 0,02897891 ! limbic system development GO:0021761 40 18 1,000 6,93E-04 0,03194127 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 7,734E-04 0,0349888 ! response to lipopolysaccharide GO:0032496 34 19 1,000 7,734E-04 0,03435264 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 8,497E-04 0,03706778 ! negative regulation of translation GO:0017148 32 20 1,000 8,581E-04 0,03677864 ! tube morphogenesis GO:0035239 194 89 2,000 9,709E-04 0,04089558 ! gluconeogenesis GO:0006094 38 23 1,000 1,138E-03 0,04711473 ! response to molecule of bacterial origin GO:0002237 40 23 1,000 1,138E-03 0,04632948 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 1,24E-03 0,049643 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 1,000 1,24E-03 0,04884231 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! pallium development GO:0021543 56 24 1,000 1,24E-03 0,04806703 ! pyruvate metabolic process GO:0006090 43 26 1,000 1,456E-03 0,05556019 ! negative regulation of cell development GO:0010721 83 26 1,000 1,456E-03 0,05470541 GO:0050768|negative regulation of neurogenesis, ! response to estradiol stimulus GO:0032355 43 26 1,000 1,456E-03 0,05387654 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 1,57E-03 0,05723788 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 1,688E-03 0,0606492 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 1,811E-03 0,06410771 ! immune response-activating signal transduction GO:0002757 58 30 1,000 1,937E-03 0,06761074 GO:0002764|immune response-regulating signal transduction, ! response to heat GO:0009408 54 31 1,000 2,068E-03 0,07115581 ! mesoderm formation GO:0001707 73 32 1,000 2,203E-03 0,07474055 ! hexose biosynthetic process GO:0019319 53 32 1,000 2,203E-03 0,07371671 ! formation of primary germ layer GO:0001704 76 34 1,000 2,484E-03 0,08202029 ! mesoderm morphogenesis GO:0048332 80 35 1,000 2,631E-03 0,08571119 ! telencephalon development GO:0021537 81 35 1,000 2,631E-03 0,08458341 ! monosaccharide biosynthetic process GO:0046364 57 36 1,000 2,782E-03 0,08827209 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 2,937E-03 0,09199095 ! actomyosin structure organization GO:0031032 68 37 1,000 2,937E-03 0,0908265 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 3,096E-03 0,09454156 ! alcohol biosynthetic process GO:0046165 65 42 1,000 3,771E-03 0,11372196 ! epithelial cell differentiation GO:0030855 83 43 1,000 3,949E-03 0,11765016 ! phagocytosis GO:0006909 105 44 1,000 4,131E-03 0,12159737 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 4,507E-03 0,13108638 ! negative regulation of cell migration GO:0030336 122 46 1,000 4,507E-03 0,12954419 ! response to insulin stimulus GO:0032868 98 47 1,000 4,701E-03 0,1335416 ! endosome transport GO:0016197 127 48 1,000 4,899E-03 0,13755364 ! JAK-STAT cascade GO:0007259 82 48 1,000 4,899E-03 0,13599053 ! endocrine system development GO:0035270 109 50 1,000 5,305E-03 0,1456178 ! response to temperature stimulus GO:0009266 84 51 1,000 5,514E-03 0,1496681 ! response to estrogen stimulus GO:0043627 98 52 1,000 5,726E-03 0,15372943 ! Notch signaling pathway GO:0007219 111 52 1,000 5,726E-03 0,15205846 ! regulation of translational initiation GO:0006446 87 54 1,000 6,163E-03 0,16188197 ! negative regulation of cell motion GO:0051271 142 55 1,000 6,386E-03 0,16597168 ! skeletal muscle fiber development GO:0048741 130 56 1,000 6,613E-03 0,1700694 ! muscle fiber development GO:0048747 131 57 1,000 6,844E-03 0,17417448 ! gastrulation GO:0007369 122 58 1,000 7,079E-03 0,17828626 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 7,804E-03 0,19454676 ! regulation of mitosis GO:0007088 112 63 1,000 8,306E-03 0,20495319 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 1,000 8,306E-03 0,20290366 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 8,561E-03 0,20708625 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 8,561E-03 0,20505599 ! chromosome segregation GO:0007059 127 67 1,000 9,35E-03 0,22177757 ! activation of immune response GO:0002253 120 70 1,000 0,01017055 0,23891024 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 0,01017055 0,2366349 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01078542 0,24857344 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01078542 0,24625032 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01078542 0,24397022 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01078542 0,24173197 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01078542 0,2395344 ! neuron fate determination GO:0048664 7 5 0,000 0,01078542 0,23737643 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01078542 0,235257 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01078542 0,23317508 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01078542 0,23112969 ! polyol transport GO:0015791 12 5 0,000 0,01078542 0,22911986 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01078542 0,22714469 ! response to superoxide GO:0000303 10 5 0,000 0,01078542 0,22520328 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01078542 0,22329478 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01078542 0,22141835 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01078542 0,2195732 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01078542 0,21775855 ! female meiosis GO:0007143 10 5 0,000 0,01078542 0,21597364 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01078542 0,21421776 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01078542 0,2124902 ! hypothalamus development GO:0021854 9 5 0,000 0,01078542 0,21079027 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01078542 0,20911733 ! cobalt ion transport GO:0006824 11 5 0,000 0,01078542 0,20747074 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01078542 0,20584988 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01078542 0,20425414 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01078542 0,20268296 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01078542 0,20113576 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01078542 0,199612 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01078542 0,19811116 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01078542 0,19663272 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01078542 0,19517618 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01078542 0,19374106 ! transposition GO:0032196 9 5 0,000 0,01078542 0,19232689 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01078542 0,19093322 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01078542 0,1895596 ! negative chemotaxis GO:0050919 16 5 0,000 0,01078542 0,1882056 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01078542 0,18687081 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01078542 0,18555482 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01078542 0,18425723 ! behavioral response to pain GO:0048266 10 5 0,000 0,01078542 0,18297767 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01078542 0,18171575 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01078542 0,18047112 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01078542 0,17924343 ! micturition GO:0060073 9 5 0,000 0,01078542 0,17803233 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01078542 0,17683748 ! copulation GO:0007620 9 5 0,000 0,01078542 0,17565856 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01078542 0,17449526 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01078542 0,17334726 ! bioluminescence GO:0008218 9 5 0,000 0,01078542 0,17221428 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01078542 0,171096 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01078542 0,16999216 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01078542 0,16890246 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01078542 0,16782665 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01078542 0,16676446 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01078542 0,16571562 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01078542 0,1646799 ! grooming behavior GO:0007625 6 5 0,000 0,01078542 0,16365704 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01078542 0,16264682 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01078542 0,16164898 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01078542 0,16066332 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01078542 0,1596896 ! response to protozoan GO:0001562 13 5 0,000 0,01078542 0,15872762 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,01078542 0,15777715 ! lymph vessel development GO:0001945 10 5 0,000 0,01078542 0,156838 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01078542 0,15590997 ! endochondral ossification GO:0001958 17 5 0,000 0,01078542 0,15499285 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01078542 0,15408646 ! single strand break repair GO:0000012 8 5 0,000 0,01078542 0,15319061 ! parathyroid gland development GO:0060017 14 5 0,000 0,01078542 0,15230511 ! anagen GO:0042640 7 5 0,000 0,01078542 0,15142979 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01078542 0,15056448 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01078542 0,149709 ! cytokine secretion GO:0050663 15 5 0,000 0,01078542 0,14886319 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01078542 0,14802688 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01078542 0,14719991 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01078542 0,14638213 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01078542 0,14557339 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01078542 0,14477354 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01078542 0,14398243 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01078542 0,14319991 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01078542 0,14242586 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01078542 0,14166013 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01078542 0,14090259 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01078542 0,14015311 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01078542 0,13941156 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01078542 0,13867781 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01078542 0,13795175 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01078542 0,13723325 ! microvillus organization GO:0032528 8 5 0,000 0,01078542 0,1365222 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01078542 0,13581848 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01078542 0,13512197 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01078542 0,13443257 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01078542 0,13375017 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01078542 0,13307467 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01078542 0,13240595 ! polyol catabolic process GO:0046174 9 5 0,000 0,01078542 0,13174392 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01078542 0,13108848 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01078542 0,13043953 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01078542 0,12979697 ! mitochondrial fission GO:0000266 8 5 0,000 0,01078542 0,12916071 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01078542 0,12853065 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01078542 0,12790672 ! mRNA transcription GO:0009299 10 5 0,000 0,01078542 0,12728881 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01078542 0,12667685 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01078542 0,12607074 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01078542 0,1254704 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01078542 0,12487575 ! monocyte activation GO:0042117 10 5 0,000 0,01078542 0,12428672 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01078542 0,12370321 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01078542 0,12312516 ! response to food GO:0032094 6 5 0,000 0,01078542 0,12255248 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01078542 0,12198511 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01078542 0,12142297 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01078542 0,12086598 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01078542 0,12031408 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,01078542 0,1197672 ! forebrain neuron development GO:0021884 13 5 0,000 0,01078542 0,11922527 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01078542 0,11868822 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01078542 0,11815598 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01078542 0,1176285 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01078542 0,11710571 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01078542 0,11658754 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01078542 0,11607394 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01078542 0,11556484 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01078542 0,11506019 ! lipid glycosylation GO:0030259 7 5 0,000 0,01078542 0,11455993 ! nucleobase transport GO:0015851 6 5 0,000 0,01078542 0,114064 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01078542 0,11357235 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01078542 0,11308491 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01078542 0,11260164 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01078542 0,11212249 ! basic amino acid transport GO:0015802 12 5 0,000 0,01078542 0,11164739 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01078542 0,1111763 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01078542 0,11070918 ! actin nucleation GO:0045010 11 5 0,000 0,01078542 0,11024596 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01078542 0,1097866 ! depurination GO:0045007 5 5 0,000 0,01078542 0,10933105 ! depyrimidination GO:0045008 10 5 0,000 0,01078542 0,10887927 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01078542 0,10843121 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01078542 0,10798682 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01078542 0,10754606 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01078542 0,10710888 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01078542 0,10667524 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01078542 0,1062451 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01078542 0,10581841 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01078542 0,10539514 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01078542 0,10497524 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01078542 0,10455867 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01078542 0,10414539 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01078542 0,10373537 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01078542 0,10332857 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01078542 0,10292494 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01078542 0,10252445 ! response to arsenic GO:0046685 11 5 0,000 0,01078542 0,10212707 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01078542 0,10173276 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01078542 0,10134148 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01078542 0,1009532 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01078542 0,10056788 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01078542 0,10018549 ! response to mercury ion GO:0046689 8 5 0,000 0,01078542 0,099806 ! response to cadmium ion GO:0046686 7 5 0,000 0,01078542 0,09942937 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01078542 0,09905558 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01078542 0,09868459 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01078542 0,09831636 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01078542 0,09795087 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01078542 0,09758809 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01078542 0,09722799 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01078542 0,09687053 ! decidualization GO:0046697 11 5 0,000 0,01078542 0,09651569 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01078542 0,09616345 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01078542 0,09581376 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01078542 0,09546661 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01078542 0,09512196 ! embryonic cleavage GO:0040016 6 5 0,000 0,01078542 0,0947798 ! peroxisome fission GO:0016559 5 5 0,000 0,01078542 0,09444009 ! histone demethylation GO:0016577 13 5 0,000 0,01078542 0,0941028 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01078542 0,09376792 ! mitotic recombination GO:0006312 9 5 0,000 0,01078542 0,0934354 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01078542 0,09310524 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01078542 0,09277741 ! metaphase plate congression GO:0051310 7 5 0,000 0,01078542 0,09245187 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01078542 0,09212862 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01078542 0,09180761 ! enteric nervous system development GO:0048484 8 5 0,000 0,01078542 0,09148883 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01078542 0,09117226 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01078542 0,09085788 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01078542 0,09054565 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01078542 0,09023556 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01078542 0,08992759 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01078542 0,08962171 ! B cell homeostasis GO:0001782 13 5 0,000 0,01078542 0,08931791 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01078542 0,08901616 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01078542 0,08871645 ! metaphase GO:0051323 11 5 0,000 0,01078542 0,08841874 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01078542 0,08812302 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01078542 0,08782928 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01078542 0,08753749 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01078542 0,08724763 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01078542 0,08695968 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01078542 0,08667363 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01078542 0,08638946 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01078542 0,08610714 ! response to redox state GO:0051775 6 5 0,000 0,01078542 0,08582666 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01078542 0,085548 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01078542 0,08527115 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01078542 0,08499608 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01078542 0,08472278 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01078542 0,08445123 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01078542 0,08418142 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01078542 0,08391333 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01078542 0,08364693 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01078542 0,08338223 ! striatum development GO:0021756 14 5 0,000 0,01078542 0,08311919 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01078542 0,08285781 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01078542 0,08259807 ! glial cell migration GO:0008347 10 5 0,000 0,01078542 0,08233995 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01078542 0,08208344 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01078542 0,08182852 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01078542 0,08157518 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01078542 0,08132341 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01078542 0,08107318 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01078542 0,08082449 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01078542 0,08057732 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01078542 0,08033166 ! neuroprotection GO:0043526 8 5 0,000 0,01078542 0,08008749 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01078542 0,0798448 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01078542 0,07960358 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01078542 0,07936381 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01078542 0,07912548 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01078542 0,07888858 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01078542 0,07865309 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01078542 0,078419 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01078542 0,0781863 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01078542 0,07795498 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01078542 0,07772503 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,01078542 0,07749642 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01078542 0,07726916 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01078542 0,07704323 ! spindle assembly GO:0051225 6 5 0,000 0,01078542 0,07681861 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01078542 0,0765953 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01078542 0,07637329 ! protein palmitoylation GO:0018345 12 5 0,000 0,01078542 0,07615256 ! drug metabolic process GO:0017144 7 5 0,000 0,01078542 0,0759331 ! stem cell division GO:0017145 11 5 0,000 0,01078542 0,0757149 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01078542 0,07549795 ! organ regeneration GO:0031100 7 5 0,000 0,01078542 0,07528224 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01078542 0,07506776 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01078542 0,0748545 ! rhythmic process GO:0048511 142 75 1,000 0,01160559 0,08031857 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,01281383 0,08842993 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01292869 0,08897122 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01292869 0,0887213 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01292869 0,08847278 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01292869 0,08822565 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01292869 0,0879799 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01292869 0,08773551 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01292869 0,08749247 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01292869 0,08725078 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01292869 0,08701042 ! response to oxygen radical GO:0000305 11 6 0,000 0,01292869 0,08677138 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01292869 0,08653365 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01292869 0,08629722 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01292869 0,08606208 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01292869 0,08582821 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01292869 0,08559562 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01292869 0,08536428 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01292869 0,08513418 ! forebrain regionalization GO:0021871 9 6 0,000 0,01292869 0,08490533 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01292869 0,0846777 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01292869 0,08445129 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01292869 0,08422609 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01292869 0,08400208 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01292869 0,08377926 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01292869 0,08355763 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01292869 0,08333716 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01292869 0,08311785 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01292869 0,08289969 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01292869 0,08268268 ! malate metabolic process GO:0006108 13 6 0,000 0,01292869 0,0824668 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01292869 0,08225204 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01292869 0,0820384 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01292869 0,08182586 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01292869 0,08161443 ! protein refolding GO:0042026 15 6 0,000 0,01292869 0,08140408 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01292869 0,08119481 ! opsonization GO:0008228 8 6 0,000 0,01292869 0,08098662 ! mating behavior GO:0007617 7 6 0,000 0,01292869 0,08077949 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01292869 0,08057342 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01292869 0,0803684 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01292869 0,08016442 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01292869 0,07996147 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01292869 0,07975955 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01292869 0,07955865 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01292869 0,07935875 ! toxin metabolic process GO:0009404 11 6 0,000 0,01292869 0,07915986 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01292869 0,07896196 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01292869 0,07876504 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01292869 0,07856911 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01292869 0,07837415 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01292869 0,07818015 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01292869 0,07798712 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01292869 0,07779503 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01292869 0,07760389 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01292869 0,07741368 ! thymic T cell selection GO:0045061 16 6 0,000 0,01292869 0,07722441 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01292869 0,07703605 ! protein lipoylation GO:0009249 10 6 0,000 0,01292869 0,07684862 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01292869 0,07666209 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01292869 0,07647647 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01292869 0,07629175 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01292869 0,07610791 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01292869 0,07592496 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01292869 0,07574288 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01292869 0,07556168 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01292869 0,07538134 ! hyperosmotic response GO:0006972 10 6 0,000 0,01292869 0,07520186 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01292869 0,07502324 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01292869 0,07484546 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01292869 0,07466852 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01292869 0,07449241 ! urea metabolic process GO:0019627 7 6 0,000 0,01292869 0,07431714 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01292869 0,07414268 ! neutrophil activation GO:0042119 7 6 0,000 0,01292869 0,07396905 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01292869 0,07379622 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01292869 0,0736242 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01292869 0,07345298 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01292869 0,07328256 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01292869 0,07311292 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01292869 0,07294407 ! neuron apoptosis GO:0051402 15 6 0,000 0,01292869 0,072776 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01292869 0,0726087 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01292869 0,07244216 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01292869 0,07227639 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01292869 0,07211138 ! carnitine transport GO:0015879 10 6 0,000 0,01292869 0,07194711 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01292869 0,0717836 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01292869 0,07162082 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01292869 0,07145878 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01292869 0,07129748 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01292869 0,0711369 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01292869 0,07097704 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01292869 0,0708179 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01292869 0,07065947 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01292869 0,07050175 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01292869 0,07034473 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01292869 0,07018841 ! neural nucleus development GO:0048857 19 6 0,000 0,01292869 0,07003278 ! response to UV-C GO:0010225 14 6 0,000 0,01292869 0,06987784 ! astrocyte development GO:0014002 16 6 0,000 0,01292869 0,06972358 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01292869 0,06957001 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01292869 0,0694171 ! interaction with symbiont GO:0051702 14 6 0,000 0,01292869 0,06926487 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01292869 0,06911331 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01292869 0,06896241 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01292869 0,06881216 ! response to copper ion GO:0046688 10 6 0,000 0,01292869 0,06866257 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01292869 0,06851363 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01292869 0,06836533 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01292869 0,06821767 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01292869 0,06807065 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01292869 0,06792426 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01292869 0,0677785 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01292869 0,06763337 ! hair follicle maturation GO:0048820 8 6 0,000 0,01292869 0,06748885 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01292869 0,06734495 ! Schwann cell development GO:0014044 15 6 0,000 0,01292869 0,06720166 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01292869 0,06705899 ! response to pheromone GO:0019236 6 6 0,000 0,01292869 0,06691691 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01292869 0,06677544 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01292869 0,06663456 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01292869 0,06649428 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01292869 0,06635459 ! subpallium development GO:0021544 15 6 0,000 0,01292869 0,06621548 ! neural tube patterning GO:0021532 8 6 0,000 0,01292869 0,06607695 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01292869 0,065939 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01292869 0,06580163 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01292869 0,06566483 ! G2 phase GO:0051319 16 6 0,000 0,01292869 0,06552859 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01292869 0,06539292 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01292869 0,06525782 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01292869 0,06512326 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01292869 0,06498926 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01292869 0,06485582 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01292869 0,06472291 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01292869 0,06459056 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01292869 0,06445874 ! receptor internalization GO:0031623 11 6 0,000 0,01292869 0,06432746 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01292869 0,06419671 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01292869 0,0640665 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01292869 0,06393681 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01292869 0,06380764 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01292869 0,063679 ! protein deubiquitination GO:0016579 16 6 0,000 0,01292869 0,06355087 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01292869 0,06342326 ! protein destabilization GO:0031648 9 6 0,000 0,01292869 0,06329616 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01292869 0,06316957 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01292869 0,06304348 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01292869 0,06291789 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01292869 0,06279281 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01292869 0,06266822 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01292869 0,06254412 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01292869 0,06242052 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01292869 0,0622974 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01292869 0,06217477 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01292869 0,06205262 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01292869 0,06193095 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01292869 0,06180975 ! neural plate development GO:0001840 9 6 0,000 0,01292869 0,06168903 ! catecholamine transport GO:0051937 9 6 0,000 0,01292869 0,06156878 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01292869 0,06144899 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01292869 0,06132967 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01292869 0,06121082 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01292869 0,06109242 ! maternal placenta development GO:0001893 12 6 0,000 0,01292869 0,06097448 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01292869 0,060857 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01292869 0,06073997 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01292869 0,06062338 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01292869 0,06050725 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01292869 0,06039155 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01292869 0,0602763 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01292869 0,06016149 GO:0055081|anion homeostasis, ! meiosis GO:0007126 143 81 1,000 0,01343769 0,06241116 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 144 82 1,000 0,01375449 0,06376135 ! inorganic anion transport GO:0015698 156 83 1,000 0,01407453 0,06512138 ! tRNA transcription GO:0009304 17 7 0,000 0,01506737 0,06958333 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01506737 0,06945204 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01506737 0,06932125 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01506737 0,06919095 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01506737 0,06906113 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01506737 0,0689318 ! sleep GO:0030431 16 7 0,000 0,01506737 0,06880296 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01506737 0,0686746 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01506737 0,06854671 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01506737 0,0684193 ! prostate gland development GO:0030850 14 7 0,000 0,01506737 0,06829236 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01506737 0,0681659 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01506737 0,0680399 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01506737 0,06791436 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01506737 0,06778929 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01506737 0,06766468 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01506737 0,06754052 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01506737 0,06741682 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01506737 0,06729357 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01506737 0,06717077 ! glycolipid transport GO:0046836 11 7 0,000 0,01506737 0,06704842 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01506737 0,06692652 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01506737 0,06680505 ! neuron adhesion GO:0007158 14 7 0,000 0,01506737 0,06668403 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,01506737 0,06656344 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01506737 0,06644329 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01506737 0,06632357 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01506737 0,06620429 ! mRNA stabilization GO:0048255 18 7 0,000 0,01506737 0,06608543 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01506737 0,065967 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01506737 0,06584899 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01506737 0,0657314 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01506737 0,06561423 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01506737 0,06549748 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01506737 0,06538114 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01506737 0,06526522 ! lipoprotein transport GO:0042953 14 7 0,000 0,01506737 0,06514971 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01506737 0,0650346 ! rhythmic behavior GO:0007622 17 7 0,000 0,01506737 0,0649199 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01506737 0,0648056 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01506737 0,06469171 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01506737 0,06457822 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01506737 0,06446512 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01506737 0,06435242 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01506737 0,06424011 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01506737 0,06412819 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01506737 0,06401667 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01506737 0,06390553 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01506737 0,06379477 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01506737 0,0636844 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01506737 0,06357441 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01506737 0,0634648 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01506737 0,06335557 ! spinal cord patterning GO:0021511 14 7 0,000 0,01506737 0,06324671 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01506737 0,06313822 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01506737 0,06303011 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01506737 0,06292236 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01506737 0,06281499 ! adrenal gland development GO:0030325 17 7 0,000 0,01506737 0,06270798 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01506737 0,06260133 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01506737 0,06249505 ! ovulation GO:0030728 10 7 0,000 0,01506737 0,06238912 ! adenohypophysis development GO:0021984 11 7 0,000 0,01506737 0,06228356 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01506737 0,06217835 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01506737 0,0620735 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01506737 0,061969 ! microtubule nucleation GO:0007020 21 7 0,000 0,01506737 0,06186485 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01506737 0,06176105 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01506737 0,06165759 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01506737 0,06155449 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01506737 0,06145173 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01506737 0,06134931 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01506737 0,06124723 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01506737 0,06114549 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01506737 0,06104409 ! galactose metabolic process GO:0006012 13 7 0,000 0,01506737 0,06094302 ! vesicle fusion GO:0006906 20 7 0,000 0,01506737 0,06084229 ! response to dietary excess GO:0002021 8 7 0,000 0,01506737 0,06074189 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01506737 0,06064182 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01506737 0,06054208 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01506737 0,06044267 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01506737 0,06034358 ! organ growth GO:0035265 15 7 0,000 0,01506737 0,06024482 ! nucleoside transport GO:0015858 11 7 0,000 0,01506737 0,06014638 ! nucleoside salvage GO:0043174 11 7 0,000 0,01506737 0,06004826 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01506737 0,05995046 ! male sex determination GO:0030238 15 7 0,000 0,01506737 0,05985298 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01506737 0,05975582 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01506737 0,05965897 ! parturition GO:0007567 16 7 0,000 0,01506737 0,05956243 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01506737 0,05946621 ! rRNA modification GO:0000154 14 7 0,000 0,01506737 0,0593703 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01506737 0,05927469 ! spindle checkpoint GO:0031577 16 7 0,000 0,01506737 0,05917939 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01506737 0,0590844 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01506737 0,05898972 ! monocyte differentiation GO:0030224 16 7 0,000 0,01506737 0,05889533 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01506737 0,05880125 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01506737 0,05870747 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01506737 0,05861399 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01506737 0,0585208 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01506737 0,05842791 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01506737 0,05833531 ! fibrinolysis GO:0042730 11 7 0,000 0,01506737 0,05824301 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01506737 0,058151 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01506737 0,05805928 ! eating behavior GO:0042755 8 7 0,000 0,01506737 0,05796785 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01506737 0,0578767 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01506737 0,05778585 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01506737 0,05769527 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01506737 0,05760498 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01506737 0,05751497 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01506737 0,05742525 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01506737 0,0573358 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01506737 0,05724663 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01506737 0,05715774 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01506737 0,05706912 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01506737 0,05698078 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01506737 0,05689271 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01506737 0,05680491 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01506737 0,05671739 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01506737 0,05663013 ! histone ubiquitination GO:0016574 9 7 0,000 0,01506737 0,05654314 ! regulation of meiosis GO:0040020 12 7 0,000 0,01506737 0,05645642 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01506737 0,05636996 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01506737 0,05628377 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01506737 0,05619784 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01506737 0,05611217 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01506737 0,05602676 ! transcription termination GO:0006353 14 7 0,000 0,01506737 0,05594162 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01506737 0,05585673 ! anaphase GO:0051322 18 7 0,000 0,01506737 0,0557721 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01506737 0,05568772 ! axonal fasciculation GO:0007413 19 7 0,000 0,01506737 0,0556036 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01506737 0,05551973 GO:0045839|negative regulation of mitosis, ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01506737 0,05543612 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01506737 0,05535276 ! diuresis GO:0030146 12 7 0,000 0,01506737 0,05526964 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01506737 0,05518678 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01506737 0,05510417 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01506737 0,0550218 ! antibiotic transport GO:0042891 9 7 0,000 0,01506737 0,05493968 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01506737 0,0548578 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01506737 0,05477617 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01506737 0,05469477 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01506737 0,05461363 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01506737 0,05453272 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01506737 0,05445205 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01506737 0,05437161 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01506737 0,05429142 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01506737 0,05421146 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01506737 0,05413174 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01506737 0,05405225 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01506737 0,053973 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01506737 0,05389397 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01506737 0,05381518 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01506737 0,05373662 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01506737 0,05365828 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01506737 0,05358018 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01506737 0,0535023 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01506737 0,05342465 ! muscle adaptation GO:0043500 13 7 0,000 0,01506737 0,05334722 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01506737 0,05327002 ! retina homeostasis GO:0001895 12 7 0,000 0,01506737 0,05319304 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01506737 0,05311628 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01506737 0,05303975 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01506737 0,05296343 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01506737 0,05288733 ! response to unfolded protein GO:0006986 139 90 1,000 0,01640407 0,05749662 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,01640407 0,05741425 ! ossification GO:0001503 205 91 1,000 0,01674943 0,05853915 ! gland development GO:0048732 220 91 1,000 0,01674943 0,05845552 ! bone development GO:0060348 206 92 1,000 0,0170979 0,05958653 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,0170979 0,05950165 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01720148 0,05977697 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01720148 0,05969206 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,01720148 0,05960739 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01720148 0,05952296 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01720148 0,05943877 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01720148 0,05935482 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01720148 0,0592711 ! male meiosis GO:0007140 9 8 0,000 0,01720148 0,05918762 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01720148 0,05910437 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01720148 0,05902136 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01720148 0,05893858 ! meiotic prophase I GO:0007128 14 8 0,000 0,01720148 0,05885604 ! response to zinc ion GO:0010043 12 8 0,000 0,01720148 0,05877372 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,01720148 0,05869163 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01720148 0,05860978 ! oligopeptide transport GO:0006857 16 8 0,000 0,01720148 0,05852815 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01720148 0,05844675 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01720148 0,05836557 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01720148 0,05828462 ! signal peptide processing GO:0006465 12 8 0,000 0,01720148 0,05820389 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01720148 0,05812339 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01720148 0,05804311 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01720148 0,05796305 ! succinate metabolic process GO:0006105 17 8 0,000 0,01720148 0,05788321 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01720148 0,05780359 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01720148 0,05772419 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01720148 0,05764501 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01720148 0,05756604 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01720148 0,05748729 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01720148 0,05740876 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01720148 0,05733044 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01720148 0,05725233 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01720148 0,05717444 ! reflex GO:0060004 17 8 0,000 0,01720148 0,05709675 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01720148 0,05701928 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01720148 0,05694202 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01720148 0,05686497 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01720148 0,05678812 ! pigment granule organization GO:0048753 17 8 0,000 0,01720148 0,05671148 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01720148 0,05663505 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01720148 0,05655883 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01720148 0,05648281 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01720148 0,05640699 ! histidine catabolic process GO:0006548 10 8 0,000 0,01720148 0,05633138 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01720148 0,05625597 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01720148 0,05618076 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01720148 0,05610575 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,01720148 0,05603095 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01720148 0,05595634 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01720148 0,05588193 ! melanin metabolic process GO:0006582 17 8 0,000 0,01720148 0,05580772 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01720148 0,0557337 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01720148 0,05565988 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01720148 0,05558626 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01720148 0,05551283 ! macrophage activation GO:0042116 13 8 0,000 0,01720148 0,05543959 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01720148 0,05536655 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01720148 0,0552937 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01720148 0,05522104 ! purine salvage GO:0043101 12 8 0,000 0,01720148 0,05514857 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01720148 0,05507629 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01720148 0,0550042 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01720148 0,0549323 ! osteoblast development GO:0002076 17 8 0,000 0,01720148 0,05486059 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01720148 0,05478906 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01720148 0,05471772 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01720148 0,05464657 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01720148 0,0545756 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01720148 0,05450481 ! response to UV-B GO:0010224 17 8 0,000 0,01720148 0,05443421 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01720148 0,05436379 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01720148 0,05429355 ! intermediate filament organization GO:0045109 12 8 0,000 0,01720148 0,0542235 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01720148 0,05415362 ! cellular extravasation GO:0045123 13 8 0,000 0,01720148 0,05408393 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01720148 0,05401441 ! response to antibiotic GO:0046677 11 8 0,000 0,01720148 0,05394507 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01720148 0,05387591 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01720148 0,05380693 ! DNA topological change GO:0006265 12 8 0,000 0,01720148 0,05373812 ! response to tropane GO:0014073 15 8 0,000 0,01720148 0,05366949 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01720148 0,05360103 ! melanosome transport GO:0032402 13 8 0,000 0,01720148 0,05353275 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 0,01720148 0,05346464 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01720148 0,05339671 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01720148 0,05332895 ! mast cell activation GO:0045576 14 8 0,000 0,01720148 0,05326136 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01720148 0,05319394 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01720148 0,05312669 ! gas homeostasis GO:0033483 14 8 0,000 0,01720148 0,05305961 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01720148 0,0529927 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01720148 0,05292596 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01720148 0,05285938 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01720148 0,05279298 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01720148 0,05272674 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01720148 0,05266066 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01720148 0,05259476 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01720148 0,05252901 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01720148 0,05246343 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01720148 0,05239802 ! response to tumor cell GO:0002347 16 8 0,000 0,01720148 0,05233277 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01720148 0,05226767 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,01720148 0,05220275 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01720148 0,05213798 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01720148 0,05207337 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01720148 0,05200892 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01720148 0,05194464 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01720148 0,05188051 ! hormone catabolic process GO:0042447 17 8 0,000 0,01720148 0,05181654 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01720148 0,05175272 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01720148 0,05168907 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01720148 0,05162557 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01720148 0,05156222 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01720148 0,05149903 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01720148 0,051436 ! adult feeding behavior GO:0008343 10 8 0,000 0,01720148 0,05137312 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01720148 0,05131039 ! ATP catabolic process GO:0006200 11 8 0,000 0,01720148 0,05124782 ! blastocyst growth GO:0001832 19 8 0,000 0,01720148 0,0511854 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01720148 0,05112313 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01720148 0,05106101 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01720148 0,05099904 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01720148 0,05093722 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01720148 0,05087556 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01720148 0,05081404 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01720148 0,05075267 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01720148 0,05069145 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01720148 0,05063037 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01720148 0,05056945 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01720148 0,05050867 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01720148 0,05044803 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01720148 0,05038754 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01720148 0,0503272 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01720148 0,050267 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01720148 0,05020694 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01720148 0,05014703 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,01720148 0,05008726 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,01720148 0,05002763 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,01780406 0,05171856 ! response to protein stimulus GO:0051789 158 96 1,000 0,01852244 0,05374146 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 0,01925292 0,05579464 ! forebrain development GO:0030900 210 98 1,000 0,01925292 0,05572853 ! axon extension GO:0048675 16 9 0,000 0,01933102 0,05588839 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01933102 0,05582233 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01933102 0,05575642 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,01933102 0,05569067 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01933102 0,05562507 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01933102 0,05555963 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01933102 0,05549434 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01933102 0,05542921 ! reproductive behavior GO:0019098 22 9 0,000 0,01933102 0,05536423 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01933102 0,0552994 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01933102 0,05523472 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01933102 0,0551702 ! UTP metabolic process GO:0046051 10 9 0,000 0,01933102 0,05510582 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01933102 0,05504159 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01933102 0,05497752 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01933102 0,05491359 ! artery development GO:0060840 25 9 0,000 0,01933102 0,05484981 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01933102 0,05478618 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01933102 0,0547227 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01933102 0,05465936 ! equilibrioception GO:0050957 20 9 0,000 0,01933102 0,05459617 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01933102 0,05453313 ! chemosensory behavior GO:0007635 21 9 0,000 0,01933102 0,05447023 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01933102 0,05440747 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01933102 0,05434486 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01933102 0,0542824 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01933102 0,05422008 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01933102 0,0541579 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01933102 0,05409586 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01933102 0,05403397 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01933102 0,05397221 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01933102 0,0539106 ! protein targeting to ER GO:0045047 25 9 0,000 0,01933102 0,05384913 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01933102 0,0537878 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01933102 0,05372661 ! T cell selection GO:0045058 27 9 0,000 0,01933102 0,05366555 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,01933102 0,05360464 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01933102 0,05354386 ! glycine catabolic process GO:0006546 15 9 0,000 0,01933102 0,05348322 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01933102 0,05342272 ! endosome organization GO:0007032 20 9 0,000 0,01933102 0,05336236 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01933102 0,05330213 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01933102 0,05324204 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01933102 0,05318208 ! mannose metabolic process GO:0006013 13 9 0,000 0,01933102 0,05312226 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01933102 0,05306257 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01933102 0,05300302 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01933102 0,0529436 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01933102 0,05288431 ! receptor clustering GO:0043113 20 9 0,000 0,01933102 0,05282515 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01933102 0,05276613 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01933102 0,05270724 ! retinol metabolic process GO:0042572 20 9 0,000 0,01933102 0,05264848 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01933102 0,05258985 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01933102 0,05253135 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01933102 0,05247299 ! macrophage differentiation GO:0030225 15 9 0,000 0,01933102 0,05241475 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01933102 0,05235664 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01933102 0,05229866 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01933102 0,0522408 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01933102 0,05218308 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01933102 0,05212548 ! response to amine stimulus GO:0014075 13 9 0,000 0,01933102 0,05206801 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01933102 0,05201067 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01933102 0,05195345 ! erythrocyte development GO:0048821 17 9 0,000 0,01933102 0,05189636 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01933102 0,05183939 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01933102 0,05178255 ! renal water homeostasis GO:0003091 15 9 0,000 0,01933102 0,05172583 ! postreplication repair GO:0006301 25 9 0,000 0,01933102 0,05166924 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01933102 0,05161277 ! icosanoid secretion GO:0032309 15 9 0,000 0,01933102 0,05155643 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01933102 0,0515002 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01933102 0,0514441 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01933102 0,05138813 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01933102 0,05133227 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01933102 0,05127653 ! sterol catabolic process GO:0016127 14 9 0,000 0,01933102 0,05122092 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01933102 0,05116542 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01933102 0,05111005 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01933102 0,0510548 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01933102 0,05099966 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01933102 0,05094465 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01933102 0,05088975 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01933102 0,05083497 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01933102 0,05078031 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01933102 0,05072576 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01933102 0,05067134 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01933102 0,05061703 ! purine base metabolic process GO:0006144 25 9 0,000 0,01933102 0,05056283 ! pigment granule transport GO:0051904 17 9 0,000 0,01933102 0,05050876 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01933102 0,05045479 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01933102 0,05040095 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01933102 0,05034721 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01933102 0,0502936 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01933102 0,05024009 ! mitochondrion localization GO:0051646 18 9 0,000 0,01933102 0,0501867 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,01999539 0,05185641 GO:0060538|skeletal muscle organ development, ! positive regulation of immune response GO:0050778 175 100 1,000 0,01999539 0,05180141 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,02145601 0,05552652 ! regulation of developmental growth GO:0048638 16 10 0,000 0,02145601 0,05546776 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,02145601 0,05540913 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02145601 0,05535062 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02145601 0,05529223 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02145601 0,05523397 ! associative learning GO:0008306 21 10 0,000 0,02145601 0,05517583 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,02145601 0,05511781 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02145601 0,05505991 ! phosphate transport GO:0006817 24 10 0,000 0,02145601 0,05500214 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02145601 0,05494448 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02145601 0,05488695 ! CTP metabolic process GO:0046036 11 10 0,000 0,02145601 0,05482954 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,02145601 0,05477224 ! GTP metabolic process GO:0046039 11 10 0,000 0,02145601 0,05471507 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,02145601 0,05465802 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,02145601 0,05460108 ! social behavior GO:0035176 29 10 0,000 0,02145601 0,05454426 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02145601 0,05448756 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02145601 0,05443098 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02145601 0,05437452 ! androgen metabolic process GO:0008209 17 10 0,000 0,02145601 0,05431817 ! phospholipid efflux GO:0033700 19 10 0,000 0,02145601 0,05426194 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02145601 0,05420583 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02145601 0,05414983 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,02145601 0,05409395 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02145601 0,05403818 ! lung alveolus development GO:0048286 26 10 0,000 0,02145601 0,05398253 ! pathogenesis GO:0009405 17 10 0,000 0,02145601 0,05392699 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02145601 0,05387157 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02145601 0,05381626 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02145601 0,05376106 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02145601 0,05370598 ! endoderm development GO:0007492 18 10 0,000 0,02145601 0,05365101 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02145601 0,05359615 ! arginine catabolic process GO:0006527 17 10 0,000 0,02145601 0,05354141 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02145601 0,05348677 ! proline metabolic process GO:0006560 13 10 0,000 0,02145601 0,05343225 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02145601 0,05337784 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02145601 0,05332354 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02145601 0,05326935 ! V(D)J recombination GO:0033151 34 10 0,000 0,02145601 0,05321527 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02145601 0,0531613 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02145601 0,05310743 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02145601 0,05305368 ! B cell proliferation GO:0042100 19 10 0,000 0,02145601 0,05300004 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02145601 0,0529465 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02145601 0,05289307 ! multicellular organism growth GO:0035264 19 10 0,000 0,02145601 0,05283976 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02145601 0,05278654 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02145601 0,05273344 ! ruffle organization GO:0031529 17 10 0,000 0,02145601 0,05268044 ! epithelial cell development GO:0002064 21 10 0,000 0,02145601 0,05262755 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02145601 0,05257476 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02145601 0,05252208 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02145601 0,05246951 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02145601 0,05241704 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,02145601 0,05236467 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02145601 0,05231241 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,02145601 0,05226026 ! motor axon guidance GO:0008045 22 10 0,000 0,02145601 0,0522082 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02145601 0,05215626 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02145601 0,05210441 ! protein heterooligomerization GO:0051291 17 10 0,000 0,02145601 0,05205267 ! brain morphogenesis GO:0048854 23 10 0,000 0,02145601 0,05200103 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02145601 0,05194949 ! segment specification GO:0007379 15 10 0,000 0,02145601 0,05189806 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,02145601 0,05184672 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,02145601 0,05179549 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02145601 0,05174436 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02145601 0,05169333 ! DNA ligation GO:0006266 18 10 0,000 0,02145601 0,0516424 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02145601 0,05159157 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02145601 0,05154084 ! melanosome localization GO:0032400 16 10 0,000 0,02145601 0,05149021 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02145601 0,05143968 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,02145601 0,05138925 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02145601 0,05133892 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02145601 0,05128869 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02145601 0,05123855 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02145601 0,05118851 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02145601 0,05113857 ! protein sumoylation GO:0016925 17 10 0,000 0,02145601 0,05108873 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02145601 0,05103898 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02145601 0,05098934 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02145601 0,05093978 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02145601 0,05089033 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02145601 0,05084097 ! salivary gland development GO:0007431 28 10 0,000 0,02145601 0,0507917 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02145601 0,05074253 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,02145601 0,05069346 ! midbrain development GO:0030901 14 10 0,000 0,02145601 0,05064448 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02145601 0,0505956 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02145601 0,05054681 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02145601 0,05049811 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,02145601 0,05044951 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02145601 0,050401 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02145601 0,05035258 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02145601 0,05030426 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02145601 0,05025603 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02145601 0,05020789 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,02145601 0,05015984 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,02145601 0,05011189 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02145601 0,05006403 ! blastocyst formation GO:0001825 18 10 0,000 0,02145601 0,05001626 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02145601 0,04996858 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02145601 0,04992099 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02145601 0,04987349 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02145601 0,04982608 ! response to nicotine GO:0035094 20 10 0,000 0,02145601 0,04977876 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02145601 0,04973153 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02145601 0,0496844 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02357646 0,05454288 ! respiratory burst GO:0045730 17 11 0,000 0,02357646 0,05449128 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02357646 0,05443978 ! neuron fate specification GO:0048665 18 11 0,000 0,02357646 0,05438837 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02357646 0,05433706 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02357646 0,05428585 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,02357646 0,05423473 ! synapsis GO:0007129 14 11 0,000 0,02357646 0,05418371 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02357646 0,05413279 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,02357646 0,05408196 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,02357646 0,05403122 ! response to pain GO:0048265 27 11 0,000 0,02357646 0,05398058 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02357646 0,05393004 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02357646 0,05387959 ! blood vessel remodeling GO:0001974 30 11 0,000 0,02357646 0,05382924 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02357646 0,05377898 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,02357646 0,05372881 ! bone resorption GO:0045453 16 11 0,000 0,02357646 0,05367874 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02357646 0,05362876 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,02357646 0,05357887 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02357646 0,05352907 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02357646 0,05347937 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02357646 0,05342976 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02357646 0,05338024 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,02357646 0,05333082 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02357646 0,05328148 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02357646 0,05323224 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,02357646 0,05318309 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,02357646 0,05313403 ! UV protection GO:0009650 20 11 0,000 0,02357646 0,05308505 ! adult heart development GO:0007512 16 11 0,000 0,02357646 0,05303617 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,02357646 0,05298738 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02357646 0,05293868 ! macroautophagy GO:0016236 19 11 0,000 0,02357646 0,05289007 ! temperature homeostasis GO:0001659 18 11 0,000 0,02357646 0,05284154 ! behavioral fear response GO:0001662 27 11 0,000 0,02357646 0,05279311 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02357646 0,05274477 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02357646 0,05269651 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,02357646 0,05264834 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02357646 0,05260026 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,02357646 0,05255227 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02357646 0,05250436 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02357646 0,05245654 ! regulation of organ growth GO:0046620 14 11 0,000 0,02357646 0,05240881 ! pigment granule localization GO:0051875 20 11 0,000 0,02357646 0,05236117 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02357646 0,05231361 ! vasoconstriction GO:0042310 20 11 0,000 0,02357646 0,05226614 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02357646 0,05221875 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02357646 0,05217145 ! embryonic axis specification GO:0000578 19 11 0,000 0,02357646 0,05212424 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02357646 0,05207711 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02357646 0,05203007 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02357646 0,05198311 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02357646 0,05193623 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02357646 0,05188944 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02357646 0,05184274 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02357646 0,05179612 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02357646 0,05174958 ! prophase GO:0051324 17 11 0,000 0,02357646 0,05170313 ! nucleosome positioning GO:0016584 15 11 0,000 0,02357646 0,05165676 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02357646 0,05161047 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02357646 0,05156426 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02357646 0,05151814 ! apical protein localization GO:0045176 18 11 0,000 0,02357646 0,0514721 ! acid secretion GO:0046717 20 11 0,000 0,02357646 0,05142615 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02357646 0,05138027 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,02357646 0,05133448 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,02357646 0,05128877 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02357646 0,05124314 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,02357646 0,05119759 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02357646 0,05115212 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 0,02357646 0,05110673 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02357646 0,05106142 ! oocyte development GO:0048599 20 11 0,000 0,02357646 0,05101619 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,02357646 0,05097105 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,02357646 0,05092598 ! embryonic gut development GO:0048566 19 11 0,000 0,02357646 0,05088099 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02357646 0,05083608 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02357646 0,05079126 ! activation of innate immune response GO:0002218 16 11 0,000 0,02357646 0,05074651 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02357646 0,05070183 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,02357646 0,05065724 ! lysogeny GO:0030069 22 11 0,000 0,02357646 0,05061273 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02357646 0,05056829 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02357646 0,05052393 ! regulation of embryonic development GO:0045995 35 11 0,000 0,02357646 0,05047965 ! nucleus localization GO:0051647 22 11 0,000 0,02357646 0,05043545 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02569237 0,05491378 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02569237 0,05486578 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,02569237 0,05481786 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02569237 0,05477003 ! virus-host interaction GO:0019048 30 12 0,000 0,02569237 0,05472228 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,02569237 0,05467461 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02569237 0,05462702 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02569237 0,05457952 ! protein complex disassembly GO:0043241 28 12 0,000 0,02569237 0,0545321 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02569237 0,05448477 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,02569237 0,05443751 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,02569237 0,05439034 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02569237 0,05434325 ! T cell proliferation GO:0042098 32 12 0,000 0,02569237 0,05429624 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02569237 0,05424931 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02569237 0,05420246 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02569237 0,0541557 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02569237 0,05410901 ! drug transport GO:0015893 16 12 0,000 0,02569237 0,0540624 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02569237 0,05401588 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02569237 0,05396943 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02569237 0,05392307 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02569237 0,05387678 ! focal adhesion formation GO:0048041 37 12 0,000 0,02569237 0,05383058 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02569237 0,05378445 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02569237 0,0537384 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02569237 0,05369243 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02569237 0,05364654 ! lipid digestion GO:0044241 21 12 0,000 0,02569237 0,05360073 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02569237 0,05355499 ! entry into host cell GO:0030260 34 12 0,000 0,02569237 0,05350934 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02569237 0,05346376 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02569237 0,05341826 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02569237 0,05337283 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02569237 0,05332749 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02569237 0,05328222 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02569237 0,05323702 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02569237 0,05319191 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02569237 0,05314687 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02569237 0,0531019 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02569237 0,05305702 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02569237 0,05301221 ! cranial nerve development GO:0021545 23 12 0,000 0,02569237 0,05296747 ! fucose catabolic process GO:0019317 25 12 0,000 0,02569237 0,05292281 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02569237 0,05287822 ! histone acetylation GO:0016573 27 12 0,000 0,02569237 0,05283371 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02569237 0,05278928 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02569237 0,05274492 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,02569237 0,05270063 ! zymogen activation GO:0031638 18 12 0,000 0,02569237 0,05265642 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02569237 0,05261228 ! T cell homeostasis GO:0043029 28 12 0,000 0,02569237 0,05256822 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02569237 0,05252423 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02569237 0,05248031 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02569237 0,05243647 ! oocyte differentiation GO:0009994 21 12 0,000 0,02569237 0,0523927 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02569237 0,052349 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02569237 0,05230538 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02569237 0,05226182 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02569237 0,05221835 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02569237 0,05217494 ! defense response to fungus GO:0050832 15 12 0,000 0,02569237 0,0521316 ! embryonic placenta development GO:0001892 21 12 0,000 0,02569237 0,05208834 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02569237 0,05204515 ! response to cold GO:0009409 17 12 0,000 0,02569237 0,05200203 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02569237 0,05195898 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02569237 0,05191601 ! localization within membrane GO:0051668 26 12 0,000 0,02569237 0,0518731 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02780375 0,05608965 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02780375 0,05604337 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02780375 0,05599717 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02780375 0,05595104 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02780375 0,05590499 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02780375 0,05585901 ! peroxisomal transport GO:0043574 28 13 0,000 0,02780375 0,05581312 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02780375 0,05576729 ! cartilage condensation GO:0001502 22 13 0,000 0,02780375 0,05572154 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02780375 0,05567587 ! organelle fusion GO:0048284 36 13 0,000 0,02780375 0,05563027 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02780375 0,05558475 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02780375 0,0555393 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02780375 0,05549392 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02780375 0,05544862 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,02780375 0,05540339 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02780375 0,05535824 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02780375 0,05531316 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02780375 0,05526815 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02780375 0,05522322 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02780375 0,05517836 ! methionine metabolic process GO:0006555 31 13 0,000 0,02780375 0,05513357 ! plasma membrane organization GO:0007009 27 13 0,000 0,02780375 0,05508886 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02780375 0,05504421 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02780375 0,05499964 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02780375 0,05495515 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02780375 0,05491072 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,02780375 0,05486637 ! cytokine metabolic process GO:0042107 24 13 0,000 0,02780375 0,05482208 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,02780375 0,05477787 ! exocrine system development GO:0035272 34 13 0,000 0,02780375 0,05473373 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02780375 0,05468966 ! monoamine transport GO:0015844 21 13 0,000 0,02780375 0,05464566 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,02780375 0,05460174 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,02780375 0,05455788 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02780375 0,05451409 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02780375 0,05447038 ! protein homotetramerization GO:0051289 24 13 0,000 0,02780375 0,05442673 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02780375 0,05438316 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02780375 0,05433965 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02780375 0,05429621 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02780375 0,05425284 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02780375 0,05420955 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02780375 0,05416632 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,02780375 0,05412316 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02780375 0,05408006 ! histone methylation GO:0016571 29 13 0,000 0,02780375 0,05403704 ! chromatin silencing GO:0006342 29 13 0,000 0,02780375 0,05399409 ! gland morphogenesis GO:0022612 31 13 0,000 0,02780375 0,0539512 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02780375 0,05390838 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,02780375 0,05386563 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02780375 0,05382295 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02780375 0,05378033 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02780375 0,05373779 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02780375 0,05369531 ! spleen development GO:0048536 24 13 0,000 0,02780375 0,05365289 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02780375 0,05361055 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02780375 0,05356827 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02780375 0,05352605 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02780375 0,05348391 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02780375 0,05344183 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02780375 0,05339981 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02780375 0,05335786 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02780375 0,05331598 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02780375 0,05327417 ! insulin secretion GO:0030073 24 13 0,000 0,02780375 0,05323241 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02780375 0,05319073 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02780375 0,05314911 ! acrosome reaction GO:0007340 19 13 0,000 0,02780375 0,05310755 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02780375 0,05306606 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02780375 0,05302464 ! rRNA transcription GO:0009303 28 14 0,000 0,02991062 0,05699816 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,02991062 0,05695373 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,02991062 0,05690938 ! water transport GO:0006833 21 14 0,000 0,02991062 0,05686509 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,02991062 0,05682087 ! non-recombinational repair GO:0000726 29 14 0,000 0,02991062 0,05677672 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,02991062 0,05673264 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,02991062 0,05668863 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,02991062 0,05664468 ! RNA polyadenylation GO:0043631 32 14 0,000 0,02991062 0,0566008 ! lipid localization GO:0010876 32 14 0,000 0,02991062 0,056557 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,02991062 0,05651325 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,02991062 0,05646958 ! regulated secretory pathway GO:0045055 24 14 0,000 0,02991062 0,05642598 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,02991062 0,05638244 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,02991062 0,05633897 ! arginine metabolic process GO:0006525 21 14 0,000 0,02991062 0,05629556 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,02991062 0,05625222 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,02991062 0,05620895 ! regulation of heart rate GO:0002027 25 14 0,000 0,02991062 0,05616575 ! fear response GO:0042596 34 14 0,000 0,02991062 0,05612261 ! organic alcohol transport GO:0015850 29 14 0,000 0,02991062 0,05607954 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,02991062 0,05603653 ! embryo implantation GO:0007566 30 14 0,000 0,02991062 0,05599359 ! neutral amino acid transport GO:0015804 28 14 0,000 0,02991062 0,05595072 ! bone mineralization GO:0030282 18 14 0,000 0,02991062 0,05590791 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,02991062 0,05586517 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,02991062 0,05582249 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,02991062 0,05577988 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,02991062 0,05573733 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,02991062 0,05569485 ! regulation of cellular pH GO:0030641 27 14 0,000 0,02991062 0,05565243 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,02991062 0,05561008 ! ribosome assembly GO:0042255 18 14 0,000 0,02991062 0,05556779 ! cerebellum development GO:0021549 23 14 0,000 0,02991062 0,05552556 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,02991062 0,0554834 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,02991062 0,0554413 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,02991062 0,05539927 ! response to gamma radiation GO:0010332 30 14 0,000 0,02991062 0,0553573 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,02991062 0,0553154 ! NADP metabolic process GO:0006739 24 14 0,000 0,02991062 0,05527355 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,02991062 0,05523178 ! oxygen transport GO:0015671 22 14 0,000 0,02991062 0,05519006 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02991062 0,05514841 ! male genitalia development GO:0030539 26 14 0,000 0,02991062 0,05510682 ! regulation of RNA stability GO:0043487 33 14 0,000 0,02991062 0,05506529 ! regulation of axon extension GO:0030516 43 14 0,000 0,02991062 0,05502382 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,02991062 0,05498242 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,02991062 0,05494108 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,02991062 0,0548998 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03201298 0,05871449 ! lactation GO:0007595 30 15 0,000 0,03201298 0,05867045 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,03201298 0,05862647 ! reproductive cellular process GO:0048610 22 15 0,000 0,03201298 0,05858255 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03201298 0,0585387 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,03201298 0,05849492 ! superoxide anion generation GO:0042554 22 15 0,000 0,03201298 0,0584512 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,03201298 0,05840755 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,03201298 0,05836396 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,03201298 0,05832044 ! copper ion transport GO:0006825 22 15 0,000 0,03201298 0,05827698 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,03201298 0,05823359 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,03201298 0,05819026 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,03201298 0,05814699 ! response to cAMP GO:0051591 25 15 0,000 0,03201298 0,05810379 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,03201298 0,05806066 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,03201298 0,05801759 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,03201298 0,05797458 ! response to hexose stimulus GO:0009746 25 15 0,000 0,03201298 0,05793163 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,03201298 0,05788875 ! vesicle coating GO:0006901 38 15 0,000 0,03201298 0,05784594 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,03201298 0,05780318 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,03201298 0,05776049 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,03201298 0,05771786 ! regulation of exocytosis GO:0017157 26 15 0,000 0,03201298 0,0576753 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,03201298 0,0576328 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,03201298 0,05759036 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,03201298 0,05754798 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,03201298 0,05750567 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,03201298 0,05746341 ! regulation of vasodilation GO:0042312 27 15 0,000 0,03201298 0,05742122 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,03201298 0,05737909 ! histone deacetylation GO:0016575 24 15 0,000 0,03201298 0,05733703 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03201298 0,05729502 ! water homeostasis GO:0030104 28 15 0,000 0,03201298 0,05725308 ! cofactor transport GO:0051181 30 15 0,000 0,03201298 0,0572112 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03201298 0,05716938 ! muscle maintenance GO:0046716 26 15 0,000 0,03201298 0,05712762 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,03201298 0,05708592 ! intestinal absorption GO:0050892 31 15 0,000 0,03201298 0,05704428 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03201298 0,0570027 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,03201298 0,05696118 ! heme biosynthetic process GO:0006783 33 15 0,000 0,03201298 0,05691973 ! cell killing GO:0001906 32 15 0,000 0,03201298 0,05687833 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,03201298 0,056837 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,03201298 0,05679572 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,03201298 0,0567545 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,03201298 0,05671335 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,03201298 0,05667225 ! actin filament polymerization GO:0030041 27 15 0,000 0,03201298 0,05663121 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,03201298 0,05659024 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,03411084 0,06025509 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03411084 0,06021155 ! positive regulation of cell size GO:0045793 29 16 0,000 0,03411084 0,06016808 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,03411084 0,06012467 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,03411084 0,06008132 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,03411084 0,06003803 ! bone remodeling GO:0046849 28 16 0,000 0,03411084 0,05999481 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,03411084 0,05995165 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,03411084 0,05990855 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03411084 0,05986551 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,03411084 0,05982253 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,03411084 0,05977962 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,03411084 0,05973677 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,03411084 0,05969397 ! startle response GO:0001964 28 16 0,000 0,03411084 0,05965124 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,03411084 0,05960857 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,03411084 0,05956597 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,03411084 0,05952342 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,03411084 0,05948093 ! protein polyubiquitination GO:0000209 41 16 0,000 0,03411084 0,05943851 ! glutamate metabolic process GO:0006536 25 16 0,000 0,03411084 0,05939614 ! pituitary gland development GO:0021983 30 16 0,000 0,03411084 0,05935384 ! response to osmotic stress GO:0006970 27 16 0,000 0,03411084 0,05931159 ! lysosomal transport GO:0007041 31 16 0,000 0,03411084 0,05926941 ! fructose metabolic process GO:0006000 25 16 0,000 0,03411084 0,05922728 ! L-amino acid transport GO:0015807 33 16 0,000 0,03411084 0,05918522 ! stem cell development GO:0048864 46 16 0,000 0,03411084 0,05914321 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03411084 0,05910127 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03411084 0,05905938 ! intermediate filament-based process GO:0045103 36 16 0,000 0,03411084 0,05901755 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,03411084 0,05897579 ! negative regulation of immune response GO:0050777 38 16 0,000 0,03411084 0,05893408 ! axon cargo transport GO:0008088 46 16 0,000 0,03411084 0,05889243 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,03411084 0,05885084 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,03411084 0,05880931 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,03411084 0,05876783 ! DNA replication initiation GO:0006270 28 16 0,000 0,03411084 0,05872642 ! neuron recognition GO:0008038 40 16 0,000 0,03411084 0,05868506 ! mRNA splice site selection GO:0006376 44 16 0,000 0,03411084 0,05864376 ! tissue regeneration GO:0042246 27 16 0,000 0,03411084 0,05860252 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,03411084 0,05856134 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,03411084 0,05852022 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,03411084 0,05847915 ! biomineral formation GO:0031214 22 16 0,000 0,03411084 0,05843814 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,03411084 0,05839719 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,03411084 0,05835629 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,03411084 0,05831546 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03411084 0,05827468 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,03411084 0,05823395 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,03411084 0,05819329 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,03411084 0,05815268 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,03411084 0,05811213 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03411084 0,05807163 ! peptide hormone processing GO:0016486 27 16 0,000 0,03411084 0,05803119 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,03620422 0,06154969 ! metencephalon development GO:0022037 32 17 0,000 0,03620422 0,06150689 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,03620422 0,06146415 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,03620422 0,06142146 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,03620422 0,06137884 ! signal complex assembly GO:0007172 47 17 0,000 0,03620422 0,06133627 ! filopodium assembly GO:0046847 42 17 0,000 0,03620422 0,06129377 ! endothelial cell migration GO:0043542 31 17 0,000 0,03620422 0,06125132 ! gene silencing by RNA GO:0031047 38 17 0,000 0,03620422 0,06120893 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,03620422 0,0611666 ! glial cell development GO:0021782 28 17 0,000 0,03620422 0,06112433 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,03620422 0,06108212 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,03620422 0,06103996 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,03620422 0,06099787 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,03620422 0,06095583 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,03620422 0,06091385 ! myoblast differentiation GO:0045445 50 17 0,000 0,03620422 0,06087192 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,03620422 0,06083006 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,03620422 0,06078825 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,03620422 0,0607465 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,03620422 0,06070481 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,03620422 0,06066317 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,03620422 0,06062159 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,03620422 0,06058007 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,03620422 0,06053861 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,03620422 0,0604972 ! membrane budding GO:0006900 42 17 0,000 0,03620422 0,06045585 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,03620422 0,06041455 ! regulation of protein binding GO:0043393 33 17 0,000 0,03620422 0,06037331 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,03620422 0,06033213 ! genitalia development GO:0048806 32 17 0,000 0,03620422 0,06029101 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,03620422 0,06024994 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,03620422 0,06020892 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,03620422 0,06016796 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,03620422 0,06012706 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,03620422 0,06008621 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,03620422 0,06004542 ! steroid catabolic process GO:0006706 34 17 0,000 0,03620422 0,06000468 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,03620422 0,059964 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,03620422 0,05992338 ! gas transport GO:0015669 26 17 0,000 0,03620422 0,05988281 ! organic cation transport GO:0015695 32 17 0,000 0,03620422 0,05984229 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,03620422 0,05980183 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,03620422 0,05976142 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,03829312 0,06316684 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,03829312 0,06312421 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,03829312 0,06308165 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03829312 0,06303914 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,03829312 0,06299669 ! adult walking behavior GO:0007628 36 18 0,000 0,03829312 0,0629543 ! patterning of blood vessels GO:0001569 43 18 0,000 0,03829312 0,06291196 ! heart looping GO:0001947 34 18 0,000 0,03829312 0,06286968 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,03829312 0,06282746 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,03829312 0,06278529 ! centrosome cycle GO:0007098 26 18 0,000 0,03829312 0,06274318 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,03829312 0,06270113 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,03829312 0,06265913 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,03829312 0,06261719 ! glycine metabolic process GO:0006544 30 18 0,000 0,03829312 0,06257531 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03829312 0,06253348 ! response to retinoic acid GO:0032526 31 18 0,000 0,03829312 0,06249171 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,03829312 0,06244999 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,03829312 0,06240833 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,03829312 0,06236672 ! DNA integration GO:0015074 32 18 0,000 0,03829312 0,06232517 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,03829312 0,06228368 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,03829312 0,06224224 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,03829312 0,06220085 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,03829312 0,06215952 ! neural crest cell migration GO:0001755 41 18 0,000 0,03829312 0,06211825 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,03829312 0,06207703 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,03829312 0,06203586 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,03829312 0,06199475 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,03829312 0,0619537 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,03829312 0,0619127 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,03829312 0,06187175 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,03829312 0,06183085 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,03829312 0,06179002 ! detection of bacterium GO:0016045 22 18 0,000 0,03829312 0,06174923 ! nerve development GO:0021675 34 18 0,000 0,03829312 0,0617085 ! defense response to virus GO:0051607 43 18 0,000 0,03829312 0,06166782 ! microspike assembly GO:0030035 46 18 0,000 0,03829312 0,0616272 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,03829312 0,06158662 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,03829312 0,06154611 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,04037755 0,06485361 ! positive regulation of translation GO:0045727 31 19 0,000 0,04037755 0,064811 ! negative regulation of defense response GO:0031348 27 19 0,000 0,04037755 0,06476845 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,04037755 0,06472595 ! neuron maturation GO:0042551 46 19 0,000 0,04037755 0,0646835 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,04037755 0,06464112 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,04037755 0,06459878 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,04037755 0,06455651 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,04037755 0,06451429 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,04037755 0,06447212 ! inositol metabolic process GO:0006020 33 19 0,000 0,04037755 0,06443001 ! memory GO:0007613 34 19 0,000 0,04037755 0,06438795 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,04037755 0,06434595 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,04037755 0,064304 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,04037755 0,06426211 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,04037755 0,06422028 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,04037755 0,06417849 ! cerebral cortex development GO:0021987 40 19 0,000 0,04037755 0,06413676 ! pigmentation during development GO:0048066 42 19 0,000 0,04037755 0,06409509 ! response to vitamin A GO:0033189 32 19 0,000 0,04037755 0,06405347 ! heme metabolic process GO:0042168 40 19 0,000 0,04037755 0,0640119 ! neuromuscular junction development GO:0007528 43 19 0,000 0,04037755 0,06397039 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,04037755 0,06392893 ! response to fungus GO:0009620 26 19 0,000 0,04037755 0,06388753 ! peptide cross-linking GO:0018149 39 19 0,000 0,04037755 0,06384618 ! protein export from nucleus GO:0006611 40 19 0,000 0,04037755 0,06380488 ! heart process GO:0003015 32 19 0,000 0,04037755 0,06376363 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,04037755 0,06372244 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,04037755 0,06368131 ! visual learning GO:0008542 38 19 0,000 0,04037755 0,06364022 ! cellular pigmentation GO:0033059 37 19 0,000 0,04037755 0,06359919 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,04037755 0,06355821 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,04037755 0,06351728 ! vitamin transport GO:0051180 31 19 0,000 0,04037755 0,06347641 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,04037755 0,06343559 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,04037755 0,06339482 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,04037755 0,06335411 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,04037755 0,06331344 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,04037755 0,06327283 ! cilium assembly GO:0042384 38 19 0,000 0,04037755 0,06323227 ! peptide hormone secretion GO:0030072 32 19 0,000 0,04037755 0,06319176 ! protein secretion GO:0009306 45 20 0,000 0,04245752 0,06640442 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,04245752 0,06636194 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,04245752 0,06631951 ! positive regulation of ossification GO:0045778 50 20 0,000 0,04245752 0,06627713 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,04245752 0,06623481 ! skin development GO:0043588 42 20 0,000 0,04245752 0,06619254 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,04245752 0,06615032 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,04245752 0,06610816 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,04245752 0,06606606 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,04245752 0,066024 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,04245752 0,065982 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,04245752 0,06594006 ! response to vitamin GO:0033273 36 20 0,000 0,04245752 0,06589816 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,04245752 0,06585632 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,04245752 0,06581454 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,04245752 0,0657728 ! bile acid metabolic process GO:0008206 34 20 0,000 0,04245752 0,06573112 ! response to alkaloid GO:0043279 38 20 0,000 0,04245752 0,06568949 ! retinoid metabolic process GO:0001523 34 20 0,000 0,04245752 0,06564792 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,04245752 0,06560639 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,04245752 0,06556492 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,04245752 0,06552351 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,04245752 0,06548214 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,04245752 0,06544083 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,04245752 0,06539956 ! actin filament bundle formation GO:0051017 47 20 0,000 0,04245752 0,06535836 ! body fluid secretion GO:0007589 33 20 0,000 0,04245752 0,0653172 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,04245752 0,06527609 ! peptide secretion GO:0002790 38 20 0,000 0,04245752 0,06523504 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,04245752 0,06519403 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,04245752 0,06515308 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,04245752 0,06511218 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,04245752 0,06507134 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,04245752 0,06503054 ! cell-cell junction organization GO:0045216 43 20 0,000 0,04245752 0,06498979 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,04245752 0,0649491 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,04245752 0,06490845 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,04245752 0,06486786 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,04245752 0,06482732 ! regulation of glucose import GO:0046324 30 20 0,000 0,04245752 0,06478683 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,04245752 0,06474639 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,04245752 0,06470599 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,04245752 0,06466565 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,04245752 0,06462536 ! regulation of cell killing GO:0031341 46 21 0,000 0,04453304 0,06774234 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,04453304 0,06770019 ! hormone secretion GO:0046879 39 21 0,000 0,04453304 0,06765809 ! lipid phosphorylation GO:0046834 43 21 0,000 0,04453304 0,06761604 ! cAMP metabolic process GO:0046058 41 21 0,000 0,04453304 0,06757404 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,04453304 0,06753209 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,04453304 0,0674902 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,04453304 0,06744836 ! ovarian follicle development GO:0001541 39 21 0,000 0,04453304 0,06740657 ! smooth muscle contraction GO:0006939 48 21 0,000 0,04453304 0,06736483 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,04453304 0,06732315 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,04453304 0,06728151 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,04453304 0,06723993 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,04453304 0,0671984 ! plasma membrane fusion GO:0045026 33 21 0,000 0,04453304 0,06715692 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,04453304 0,06711549 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,04453304 0,06707411 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,04453304 0,06703278 ! sensory perception of pain GO:0019233 33 21 0,000 0,04453304 0,06699151 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,04453304 0,06695028 ! diencephalon development GO:0021536 36 21 0,000 0,04453304 0,06690911 ! collagen fibril organization GO:0030199 62 21 0,000 0,04453304 0,06686798 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,04453304 0,06682691 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,04453304 0,06678588 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,04453304 0,06674491 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,04453304 0,06670399 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,04453304 0,06666312 ! collagen catabolic process GO:0030574 29 21 0,000 0,04453304 0,06662229 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,04453304 0,06658152 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,04453304 0,0665408 ! sperm-egg recognition GO:0035036 23 21 0,000 0,04453304 0,06650013 ! actin filament-based movement GO:0030048 47 21 0,000 0,04453304 0,0664595 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,04453304 0,06641893 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,04660411 0,06946544 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,04660411 0,06942308 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,04660411 0,06938078 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,04660411 0,06933852 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,04660411 0,06929632 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,04660411 0,06925417 ! microtubule-based transport GO:0010970 59 22 0,000 0,04660411 0,06921207 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,04660411 0,06917002 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,04660411 0,06912802 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,04660411 0,06908608 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,04660411 0,06904418 ! cellular response to starvation GO:0009267 37 22 0,000 0,04660411 0,06900233 ! vacuolar transport GO:0007034 41 22 0,000 0,04660411 0,06896054 ! central nervous system neuron development GO:0021954 47 22 0,000 0,04660411 0,0689188 ! fucose metabolic process GO:0006004 44 22 0,000 0,04660411 0,0688771 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,04660411 0,06883546 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,04660411 0,06879387 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,04660411 0,06875233 ! cell aging GO:0007569 48 22 0,000 0,04660411 0,06871083 ! stem cell differentiation GO:0048863 57 22 0,000 0,04660411 0,06866939 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,04660411 0,068628 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,04660411 0,06858666 ! cytolysis GO:0019835 27 22 0,000 0,04660411 0,06854537 ! renal system process GO:0003014 42 22 0,000 0,04660411 0,06850412 ! vasodilation GO:0042311 40 22 0,000 0,04660411 0,06846293 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,04660411 0,06842179 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,04660411 0,06838069 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,04660411 0,06833965 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,04660411 0,06829865 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,04660411 0,06825771 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,04660411 0,06821681 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,04660411 0,06817596 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,04660411 0,06813516 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,04660411 0,06809441 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,04660411 0,06805371 ! sarcomere organization GO:0045214 32 22 0,000 0,04660411 0,06801305 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,04660411 0,06797245 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,04660411 0,06793189 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,04660411 0,06789138 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,04660411 0,06785092 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,04660411 0,06781051 ! gut development GO:0048565 44 22 0,000 0,04660411 0,06777015 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,04660411 0,06772983 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,04660411 0,06768957 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,04660411 0,06764935 ! protein stabilization GO:0050821 41 22 0,000 0,04660411 0,06760918 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,04867076 0,07056539 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,04867076 0,07052353 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,04867076 0,07048173 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,04867076 0,07043997 ! glycerol metabolic process GO:0006071 40 23 0,000 0,04867076 0,07039827 ! viral genome replication GO:0019079 44 23 0,000 0,04867076 0,07035661 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,04867076 0,07031501 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,04867076 0,07027345 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,04867076 0,07023194 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,04867076 0,07019048 ! regeneration GO:0031099 42 23 0,000 0,04867076 0,07014907 ! axis specification GO:0009798 43 23 0,000 0,04867076 0,07010771 ! visual behavior GO:0007632 46 23 0,000 0,04867076 0,0700664 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,04867076 0,07002513 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,04867076 0,06998392 ! response to ethanol GO:0045471 47 23 0,000 0,04867076 0,06994275 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,04867076 0,06990163 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,04867076 0,06986056 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,04867076 0,06981954 ! peroxisome organization GO:0007031 43 23 0,000 0,04867076 0,06977856 ! lysosome organization GO:0007040 47 23 0,000 0,04867076 0,06973764 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,04867076 0,06969676 ! vesicle targeting GO:0006903 49 23 0,000 0,04867076 0,06965593 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,04867076 0,06961515 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,04867076 0,06957441 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,04867076 0,06953373 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,04867076 0,06949309 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,04867076 0,0694525 ! DNA modification GO:0006304 36 23 0,000 0,04867076 0,06941195 ! fatty acid transport GO:0015908 47 23 0,000 0,04867076 0,06937146 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,04867076 0,06933101 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,04867076 0,0692906 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,04867076 0,06925025 ! hormone transport GO:0009914 41 23 0,000 0,04867076 0,06920994 ! cell-cell recognition GO:0009988 28 23 0,000 0,04867076 0,06916968 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,04867076 0,06912946 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,04867076 0,06908929 GO:0006099|tricarboxylic acid cycle, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,05073299 0,07197485 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,05073299 0,07193308 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,05073299 0,07189135 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,05073299 0,07184968 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,05073299 0,07180805 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,05073299 0,07176647 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,05073299 0,07172494 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,05073299 0,07168345 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,05073299 0,07164202 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,05073299 0,07160063 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,05073299 0,07155929 ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,05073299 0,071518 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,05073299 0,07147676 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,05073299 0,07143556 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,05073299 0,07139441 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,05073299 0,07135331 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,05073299 0,07131225 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,05073299 0,07127124 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,05073299 0,07123028 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,05073299 0,07118937 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,05073299 0,0711485 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,05073299 0,07110768 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,05073299 0,07106691 ! membrane depolarization GO:0051899 45 24 0,000 0,05073299 0,07102619 ! oogenesis GO:0048477 44 24 0,000 0,05073299 0,07098551 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,05073299 0,07094487 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,05073299 0,07090429 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,05073299 0,07086375 ! platelet activation GO:0030168 41 24 0,000 0,05073299 0,07082325 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,05073299 0,07078281 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,05073299 0,0707424 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,05073299 0,07070205 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,05073299 0,07066174 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,05073299 0,07062148 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,05073299 0,07058126 ! regulation of amine transport GO:0051952 41 24 0,000 0,05073299 0,07054109 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,05073299 0,07050096 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,0527908 0,07331889 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,0527908 0,07327723 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,0527908 0,07323562 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,0527908 0,07319406 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,0527908 0,07315254 ! leukocyte adhesion GO:0007159 55 25 0,000 0,0527908 0,07311107 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,0527908 0,07306965 ! phototransduction GO:0007602 37 25 0,000 0,0527908 0,07302827 ! keratinization GO:0031424 37 25 0,000 0,0527908 0,07298695 ! vasculogenesis GO:0001570 49 25 0,000 0,0527908 0,07294566 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,0527908 0,07290443 ! vacuole organization GO:0007033 49 25 0,000 0,0527908 0,07286324 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,0527908 0,0728221 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,0527908 0,072781 ! receptor metabolic process GO:0043112 53 25 0,000 0,0527908 0,07273995 ! chromosome condensation GO:0030261 48 25 0,000 0,0527908 0,07269895 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,0527908 0,07265799 ! regulation of behavior GO:0050795 48 25 0,000 0,0527908 0,07261708 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,0527908 0,07257621 ! interaction with host GO:0051701 66 25 0,000 0,0527908 0,0725354 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,0527908 0,07249462 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,0527908 0,0724539 ! immunoglobulin production GO:0002377 62 25 0,000 0,0527908 0,07241321 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,0527908 0,07237258 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,0527908 0,07233199 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,0527908 0,07229144 ! liver development GO:0001889 55 25 0,000 0,0527908 0,07225094 ! protein tetramerization GO:0051262 57 25 0,000 0,0527908 0,07221049 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,05484421 0,07497729 ! myelination GO:0042552 50 26 0,000 0,05484421 0,07493536 ! initiation of viral infection GO:0019059 60 26 0,000 0,05484421 0,07489347 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,05484421 0,07485163 ! molting cycle process GO:0022404 52 26 0,000 0,05484421 0,07480984 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,05484421 0,07476809 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,05484421 0,07472639 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,05484421 0,07468474 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,05484421 0,07464313 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,05484421 0,07460157 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,05484421 0,07456005 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,05484421 0,07451859 ! digestive system process GO:0022600 49 26 0,000 0,05484421 0,07447716 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,05484421 0,07443579 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,05484421 0,07439446 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,05484421 0,07435317 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,05484421 0,07431193 ! osteoblast differentiation GO:0001649 63 26 0,000 0,05484421 0,07427074 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,05484421 0,07422959 ! neural crest cell development GO:0014032 59 26 0,000 0,05484421 0,07418849 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,05484421 0,07414744 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,05484421 0,07410643 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,05484421 0,07406546 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,05484421 0,07402454 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,05484421 0,07398366 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,05484421 0,07394283 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,05484421 0,07390205 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,05484421 0,07386131 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,05484421 0,07382062 ! blastocyst development GO:0001824 50 26 0,000 0,05484421 0,07377997 ! telomere organization GO:0032200 46 26 0,000 0,05484421 0,07373936 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,05484421 0,0736988 ! neural tube closure GO:0001843 58 26 0,000 0,05484421 0,07365828 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,05484421 0,07361781 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,05484421 0,07357738 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,05484421 0,073537 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,05689323 0,07624255 ! embryonic pattern specification GO:0009880 49 27 0,000 0,05689323 0,07620075 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,05689323 0,076159 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,05689323 0,07611729 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,05689323 0,07607562 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,05689323 0,07603401 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,05689323 0,07599244 ! iron ion transport GO:0006826 65 27 0,000 0,05689323 0,07595091 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,05689323 0,07590943 ! superoxide metabolic process GO:0006801 41 27 0,000 0,05689323 0,07586799 ! tube lumen formation GO:0035148 59 27 0,000 0,05689323 0,0758266 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,05689323 0,07578526 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,05689323 0,07574396 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,05689323 0,0757027 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,05689323 0,07566149 ! response to starvation GO:0042594 47 27 0,000 0,05689323 0,07562033 ! response to toxin GO:0009636 49 27 0,000 0,05689323 0,07557921 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,05689323 0,07553813 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,05689323 0,0754971 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,05689323 0,07545612 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,05689323 0,07541517 ! leukocyte proliferation GO:0070661 59 27 0,000 0,05689323 0,07537428 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,05689323 0,07533342 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,05893786 0,07799849 ! neuron fate commitment GO:0048663 52 28 0,000 0,05893786 0,07795626 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,05893786 0,07791407 ! protein amino acid acylation GO:0043543 59 28 0,000 0,05893786 0,07787193 ! vesicle docking GO:0048278 55 28 0,000 0,05893786 0,07782984 ! circadian rhythm GO:0007623 56 28 0,000 0,05893786 0,07778779 ! dendrite development GO:0016358 67 28 0,000 0,05893786 0,07774579 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,05893786 0,07770383 ! fat cell differentiation GO:0045444 57 28 0,000 0,05893786 0,07766192 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,05893786 0,07762006 ! sperm motility GO:0030317 37 28 0,000 0,05893786 0,07757823 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,05893786 0,07753646 ! base-excision repair GO:0006284 41 28 0,000 0,05893786 0,07749473 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,05893786 0,07745304 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,05893786 0,0774114 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,05893786 0,0773698 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,05893786 0,07732825 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,05893786 0,07728674 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,05893786 0,07724528 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,05893786 0,07720386 ! glutathione metabolic process GO:0006749 42 28 0,000 0,05893786 0,07716249 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,05893786 0,07712116 ! lipid oxidation GO:0034440 48 28 0,000 0,05893786 0,07707987 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,05893786 0,07703863 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,05893786 0,07699744 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,06097812 0,07962028 ! translational initiation GO:0006413 66 29 0,000 0,06097812 0,07957775 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,06097812 0,07953527 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,06097812 0,07949282 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,06097812 0,07945043 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,06097812 0,07940808 ! autophagy GO:0006914 47 29 0,000 0,06097812 0,07936577 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,06097812 0,07932351 ! primary neural tube formation GO:0014020 61 29 0,000 0,06097812 0,07928129 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,06097812 0,07923912 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,06097812 0,079197 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,06097812 0,07915492 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,06097812 0,07911288 ! somitogenesis GO:0001756 52 29 0,000 0,06097812 0,07907089 ! synaptogenesis GO:0007416 46 29 0,000 0,06097812 0,07902894 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,06097812 0,07898704 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,06097812 0,07894518 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,06097812 0,07890336 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,06301401 0,08149457 ! phenol metabolic process GO:0018958 56 30 0,000 0,06301401 0,08145145 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,06301401 0,08140837 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,06301401 0,08136535 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,06301401 0,08132236 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,06301401 0,08127943 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,06301401 0,08123654 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,06301401 0,08119369 ! acute-phase response GO:0006953 50 30 0,000 0,06301401 0,08115089 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,06301401 0,08110813 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,06301401 0,08106542 ! myofibril assembly GO:0030239 50 30 0,000 0,06301401 0,08102276 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,06301401 0,08098013 ! determination of left/right symmetry GO:0007368 53 30 0,000 0,06301401 0,08093756 ! cell fate determination GO:0001709 64 30 0,000 0,06301401 0,08089503 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,06301401 0,08085254 ! phospholipid transport GO:0015914 65 30 0,000 0,06301401 0,0808101 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,06301401 0,0807677 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,06301401 0,08072535 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,06301401 0,08068304 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,06301401 0,08064077 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,06301401 0,08059855 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,06301401 0,08055638 ! regulation of coagulation GO:0050818 52 30 0,000 0,06301401 0,08051424 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,06504555 0,08306653 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,06504555 0,08302313 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,06504555 0,08297978 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,06504555 0,08293647 ! cell junction assembly GO:0034329 85 31 0,000 0,06504555 0,08289321 ! regulation of innate immune response GO:0045088 57 31 0,000 0,06504555 0,08284999 ! ovulation cycle process GO:0022602 55 31 0,000 0,06504555 0,08280681 ! peptide transport GO:0015833 60 31 0,000 0,06504555 0,08276368 ! male gonad development GO:0008584 56 31 0,000 0,06504555 0,0827206 ! iron ion homeostasis GO:0055072 60 31 0,000 0,06504555 0,08267756 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,06504555 0,08263457 ! detection of light stimulus GO:0009583 44 31 0,000 0,06504555 0,08259162 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,06504555 0,08254871 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,06504555 0,08250585 ! natural killer cell activation GO:0030101 50 31 0,000 0,06504555 0,08246304 ! ensheathment of neurons GO:0007272 64 31 0,000 0,06504555 0,08242027 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,06504555 0,08237754 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,06504555 0,08233486 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,06504555 0,08229222 ! eye morphogenesis GO:0048592 65 31 0,000 0,06504555 0,08224962 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,06504555 0,08220707 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,06707274 0,08472528 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,06707274 0,08468149 ! collagen metabolic process GO:0032963 49 32 0,000 0,06707274 0,08463775 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,06707274 0,08459406 ! spindle organization GO:0007051 50 32 0,000 0,06707274 0,08455041 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,06707274 0,0845068 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,06707274 0,08446324 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,06707274 0,08441973 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,06707274 0,08437626 ! muscle cell development GO:0055001 52 32 0,000 0,06707274 0,08433283 ! ovulation cycle GO:0042698 57 32 0,000 0,06707274 0,08428945 ! peripheral nervous system development GO:0007422 68 32 0,000 0,06707274 0,08424611 ! BMP signaling pathway GO:0030509 71 32 0,000 0,06707274 0,08420282 ! hindbrain development GO:0030902 65 32 0,000 0,06707274 0,08415958 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,06707274 0,08411637 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,06707274 0,08407321 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,06707274 0,0840301 ! gene silencing GO:0016458 71 32 0,000 0,06707274 0,08398703 ! regulation of pH GO:0006885 56 33 0,000 0,06909558 0,08647567 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,06909558 0,08643139 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,06909558 0,08638716 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,06909558 0,08634297 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,06909558 0,08629883 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,06909558 0,08625473 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,06909558 0,08621068 ! response to ionizing radiation GO:0010212 74 33 0,000 0,06909558 0,08616667 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,06909558 0,08612271 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,06909558 0,08607879 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,06909558 0,08603492 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,06909558 0,08599109 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,06909558 0,08594731 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,06909558 0,08590357 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,06909558 0,08585987 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,0711141 0,08832321 ! glial cell differentiation GO:0010001 67 34 0,000 0,0711141 0,08827833 ! post-embryonic development GO:0009791 76 34 0,000 0,0711141 0,0882335 ! cholesterol transport GO:0030301 62 34 0,000 0,0711141 0,08818871 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,0711141 0,08814396 ! spliceosome assembly GO:0000245 75 34 0,000 0,0711141 0,08809927 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,0711141 0,08805461 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,0711141 0,08801001 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,0711141 0,08796545 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,0711141 0,08792093 ! adult locomotory behavior GO:0008344 62 34 0,000 0,0711141 0,08787646 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,0711141 0,08783203 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,0731283 0,0902741 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,0731283 0,09022851 ! negative regulation of secretion GO:0051048 68 35 0,000 0,0731283 0,09018296 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,0731283 0,09013746 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,0731283 0,090092 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,0731283 0,09004659 ! membrane docking GO:0022406 69 35 0,000 0,0731283 0,09000123 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,0731283 0,08995591 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,0731283 0,08991064 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,0731283 0,08986541 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,0731283 0,08982023 ! ceramide metabolic process GO:0006672 72 35 0,000 0,0731283 0,0897751 ! sterol transport GO:0015918 63 35 0,000 0,0731283 0,08973001 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,0731283 0,08968496 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,0731283 0,08963996 ! placenta development GO:0001890 53 35 0,000 0,0731283 0,08959501 ! vesicle localization GO:0051648 70 35 0,000 0,0731283 0,0895501 ! regulation of muscle development GO:0048634 82 36 0,000 0,07513819 0,09196523 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,07513819 0,09191918 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,07513819 0,09187317 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,07513819 0,09182721 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,07513819 0,0917813 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,07513819 0,09173543 ! positive regulation of cell development GO:0010720 85 36 0,000 0,07513819 0,09168961 ! protein targeting to membrane GO:0006612 75 36 0,000 0,07513819 0,09164383 ! regulation of proteolysis GO:0030162 77 36 0,000 0,07513819 0,0915981 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,07513819 0,09155242 ! aerobic respiration GO:0009060 56 36 0,000 0,07513819 0,09150678 ! cytokine production GO:0001816 68 36 0,000 0,07513819 0,09146119 ! embryonic organ development GO:0048568 67 36 0,000 0,07513819 0,09141564 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,07513819 0,09137013 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,07714378 0,09376231 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,07714378 0,09371569 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,07714378 0,09366911 ! sister chromatid segregation GO:0000819 65 37 0,000 0,07714378 0,09362258 ! odontogenesis GO:0042476 74 37 0,000 0,07714378 0,09357609 ! cell junction organization GO:0034330 96 37 0,000 0,07714378 0,09352965 ! tissue remodeling GO:0048771 78 37 0,000 0,07714378 0,09348326 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,07714378 0,09343691 ! female gonad development GO:0008585 71 37 0,000 0,07714378 0,09339061 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,07714378 0,09334435 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,07714378 0,09329814 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,07714378 0,09325198 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,07914507 0,09562384 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,07914507 0,09557657 ! meiosis I GO:0007127 74 38 0,000 0,07914507 0,09552935 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,07914507 0,09548218 ! organic anion transport GO:0015711 82 38 0,000 0,07914507 0,09543505 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,07914507 0,09538797 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,07914507 0,09534093 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,07914507 0,09529394 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,07914507 0,095247 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,07914507 0,0952001 ! regulation of protein stability GO:0031647 77 38 0,000 0,07914507 0,09515325 ! spermatid development GO:0007286 69 38 0,000 0,07914507 0,09510645 ! glycogen metabolic process GO:0005977 63 38 0,000 0,07914507 0,09505969 ! pigment metabolic process GO:0042440 87 38 0,000 0,07914507 0,09501298 ! neural tube formation GO:0001841 79 38 0,000 0,07914507 0,09496631 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,08114208 0,09731473 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,08114208 0,09726698 ! negative regulation of binding GO:0051100 71 39 0,000 0,08114208 0,09721928 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,08114208 0,09717162 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,08114208 0,09712401 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,08114208 0,09707645 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,08114208 0,09702893 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,08114208 0,09698146 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,08114208 0,09693404 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,08114208 0,09688666 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,08114208 0,09683933 ! glucan metabolic process GO:0044042 64 39 0,000 0,08114208 0,09679204 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,08313482 0,09912072 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,08313482 0,09907237 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,08313482 0,09902406 ! learning GO:0007612 82 40 0,000 0,08313482 0,09897581 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,08313482 0,0989276 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,08313482 0,09887943 ! lipid homeostasis GO:0055088 75 40 0,000 0,08313482 0,09883132 ! mismatch repair GO:0006298 58 40 0,000 0,08313482 0,09878325 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,08313482 0,09873522 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,08313482 0,09868725 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,08313482 0,09863932 ! RNA export from nucleus GO:0006405 61 41 0,000 0,08512328 0,1009496 ! mRNA catabolic process GO:0006402 79 41 0,000 0,08512328 0,10090062 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,08512328 0,10085169 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,08512328 0,1008028 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,08512328 0,10075397 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,08512328 0,10070517 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,08512328 0,10065643 ! gliogenesis GO:0042063 91 41 0,000 0,08512328 0,10060773 ! feeding behavior GO:0007631 69 41 0,000 0,08512328 0,10055908 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,08512328 0,10051048 ! mesenchymal cell development GO:0014031 94 41 0,000 0,08512328 0,10046193 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,08512328 0,10041342 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,08512328 0,10036495 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,08512328 0,10031654 ! spermatid differentiation GO:0048515 73 41 0,000 0,08512328 0,10026817 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,08512328 0,10021985 ! RNA modification GO:0009451 64 41 0,000 0,08512328 0,10017157 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,0871075 0,10245721 ! organic ether metabolic process GO:0018904 59 42 0,000 0,0871075 0,1024079 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,0871075 0,10235864 ! T cell differentiation GO:0030217 93 42 0,000 0,0871075 0,10230943 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,0871075 0,10226027 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,0871075 0,10221115 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,0871075 0,10216208 ! regulation of protein secretion GO:0050708 77 42 0,000 0,0871075 0,10211306 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,0871075 0,10206408 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,0871075 0,10201516 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,08908746 0,10428398 GO:0090047|positive regulation of transcription regulator activity, ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,08908746 0,10423404 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,08908746 0,10418414 ! regulation of tube size GO:0035150 76 43 0,000 0,08908746 0,10413429 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,08908746 0,10408449 ! glucose transport GO:0015758 66 43 0,000 0,08908746 0,10403474 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,08908746 0,10398503 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,08908746 0,10393537 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,08908746 0,10388576 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,08908746 0,1038362 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,08908746 0,10378668 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,08908746 0,10373721 ! segmentation GO:0035282 78 43 0,000 0,08908746 0,10368779 ! ion transmembrane transport GO:0034220 79 43 0,000 0,08908746 0,10363842 ! neuron migration GO:0001764 85 43 0,000 0,08908746 0,10358909 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,08908746 0,10353981 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,09106319 0,10578572 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,09106319 0,10573544 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,09106319 0,10568521 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,09106319 0,10563503 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,09106319 0,10558489 ! hexose transport GO:0008645 68 44 0,000 0,09106319 0,10553481 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,09106319 0,10548477 ! striated muscle contraction GO:0006941 85 44 0,000 0,09106319 0,10543477 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,09106319 0,10538483 ! double-strand break repair GO:0006302 85 44 0,000 0,09106319 0,10533493 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,09303469 0,10756448 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,09303469 0,10751359 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,09303469 0,10746276 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,09303469 0,10741197 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,09303469 0,10736124 ! biopolymer methylation GO:0043414 91 45 0,000 0,09303469 0,10731055 ! B cell differentiation GO:0030183 124 45 0,000 0,09303469 0,1072599 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,09303469 0,10720931 ! female gamete generation GO:0007292 71 45 0,000 0,09303469 0,10715876 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,09303469 0,10710826 ! polyol metabolic process GO:0019751 77 45 0,000 0,09303469 0,10705781 ! developmental growth GO:0048589 88 45 0,000 0,09303469 0,10700741 ! maintenance of location in cell GO:0051651 101 45 0,000 0,09303469 0,10695705 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,09500196 0,10916735 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,09500196 0,10911603 ! glycolysis GO:0006096 71 46 0,000 0,09500196 0,10906475 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,09500196 0,10901352 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,09500196 0,10896234 ! leukocyte migration GO:0050900 75 46 0,000 0,09500196 0,10891121 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,09500196 0,10886013 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,09500196 0,10880909 ! pigmentation GO:0043473 103 46 0,000 0,09500196 0,1087581 ! cell growth GO:0016049 90 46 0,000 0,09500196 0,10870716 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,09500196 0,10865627 ! neural tube development GO:0021915 91 47 0,000 0,09696503 0,11084958 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,09696503 0,11079774 ! positive regulation of cell cycle GO:0045787 96 48 0,000 0,09892389 0,1129832 ! positive regulation of defense response GO:0031349 88 48 0,000 0,09892389 0,1129304 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,09892389 0,11287765 ! mitochondrial transport GO:0006839 94 48 0,000 0,09892389 0,11282496 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,09892389 0,11277231 ! cellular component disassembly GO:0022411 89 48 0,000 0,09892389 0,11271971 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,09892389 0,11266716 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,09892389 0,11261466 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,09892389 0,11256221 ! male sex differentiation GO:0046661 93 48 0,000 0,09892389 0,1125098 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,09892389 0,11245745 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,09892389 0,11240514 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,09892389 0,11235289 ! methylation GO:0032259 97 48 0,000 0,09892389 0,11230068 ! response to calcium ion GO:0051592 94 49 0,000 0,10087855 0,11446647 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,10087855 0,11441333 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,10087855 0,11436024 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,10087855 0,11430719 ! JNK cascade GO:0007254 106 49 0,000 0,10087855 0,1142542 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,10087855 0,11420125 ! protein homooligomerization GO:0051260 84 49 0,000 0,10087855 0,11414836 ! regulation of action potential GO:0001508 102 50 0,000 0,10282904 0,11630154 ! regulation of ion transport GO:0043269 86 50 0,000 0,10282904 0,11624773 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,10282904 0,11619396 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,10282904 0,11614024 ! activation of caspase activity GO:0006919 95 50 0,000 0,10282904 0,11608657 ! regulation of ossification GO:0030278 123 50 0,000 0,10282904 0,11603295 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,10282904 0,11597938 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,10282904 0,11592586 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,10282904 0,11587239 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,10282904 0,11581897 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,10282904 0,11576559 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,10477534 0,11790242 ! viral infectious cycle GO:0019058 104 51 0,000 0,10477534 0,11784814 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,10477534 0,11779391 ! peptide metabolic process GO:0006518 80 51 0,000 0,10477534 0,11773972 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,10477534 0,11768559 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,10477534 0,11763151 ! positive regulation of binding GO:0051099 88 52 0,000 0,10671748 0,11975691 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,10671748 0,11970193 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,10671748 0,11964699 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,10671748 0,11959211 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,10671748 0,11953728 ! excretion GO:0007588 87 52 0,000 0,10671748 0,11948249 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,10671748 0,11942776 ! histone modification GO:0016570 104 52 0,000 0,10671748 0,11937308 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,10671748 0,11931844 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,10671748 0,11926386 ! amino acid activation GO:0043038 98 52 0,000 0,10671748 0,11920933 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,10865546 0,12131869 ! positive regulation of growth GO:0045927 96 53 0,000 0,10865546 0,12126326 ! chromatin remodeling GO:0006338 122 53 0,000 0,10865546 0,12120789 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,10865546 0,12115257 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,10865546 0,1210973 ! vesicle organization GO:0016050 127 53 0,000 0,10865546 0,12104208 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,10865546 0,12098691 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,10865546 0,12093179 ! cartilage development GO:0051216 99 53 0,000 0,10865546 0,12087672 ! synapse organization GO:0050808 102 53 0,000 0,10865546 0,1208217 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,11058929 0,12291612 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,11058929 0,12286022 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,11058929 0,12280438 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,11058929 0,12274858 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,11058929 0,12269284 ! membrane fusion GO:0006944 122 54 0,000 0,11058929 0,12263714 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,11058929 0,1225815 ! covalent chromatin modification GO:0016569 115 54 0,000 0,11058929 0,12252591 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,11058929 0,12247037 ! regulation of cell shape GO:0008360 142 54 0,000 0,11058929 0,12241488 ! RNA catabolic process GO:0006401 103 55 0,000 0,11251898 0,1244945 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,11251898 0,12443814 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,11251898 0,12438184 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,11251898 0,12432558 ! cell recognition GO:0008037 98 55 0,000 0,11251898 0,12426937 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,11251898 0,12421322 ! cell maturation GO:0048469 107 55 0,000 0,11251898 0,12415712 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,11251898 0,12410106 ! response to UV GO:0009411 120 55 0,000 0,11251898 0,12404506 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,11444453 0,12611096 ! glucose catabolic process GO:0006007 88 56 0,000 0,11444453 0,1260541 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,11444453 0,12599729 ! regulation of DNA replication GO:0006275 105 56 0,000 0,11444453 0,12594054 ! RNA elongation GO:0006354 90 56 0,000 0,11444453 0,12588383 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 0,000 0,11636596 0,12793972 ! chloride transport GO:0006821 102 57 0,000 0,11636596 0,12788216 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,11636596 0,12782466 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,11636596 0,12776721 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,11636596 0,12770981 ! heart morphogenesis GO:0003007 105 57 0,000 0,11636596 0,12765247 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,11636596 0,12759517 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,11636596 0,12753793 ! regulation of actin filament length GO:0030832 118 58 0,000 0,11828328 0,12958119 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,11828328 0,12952311 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,11828328 0,12946508 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,11828328 0,1294071 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,11828328 0,12934917 ! aging GO:0007568 112 58 0,000 0,11828328 0,1292913 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,11828328 0,12923348 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,11828328 0,1291757 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,11828328 0,12911799 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,11828328 0,12906032 ! maintenance of location GO:0051235 124 58 0,000 0,11828328 0,1290027 ! nuclear export GO:0051168 110 59 0,000 0,12019649 0,1310308 ! establishment of organelle localization GO:0051656 122 59 0,000 0,12019649 0,13097236 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,1221056 0,13299331 ! lipid modification GO:0030258 112 60 0,000 0,1221056 0,13293404 ! DNA catabolic process GO:0006308 94 60 0,000 0,1221056 0,13287483 ! regulation of endocytosis GO:0030100 104 60 0,000 0,1221056 0,13281567 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,1221056 0,13275656 ! adult behavior GO:0030534 104 60 0,000 0,1221056 0,1326975 ! positive regulation of secretion GO:0051047 110 61 0,000 0,12401063 0,13470785 ! regulation of cellular component size GO:0032535 125 61 0,000 0,12401063 0,13464798 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,12401063 0,13458817 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,12401063 0,1345284 ! regulation of heart contraction GO:0008016 123 61 0,000 0,12401063 0,13446869 ! camera-type eye development GO:0043010 126 61 0,000 0,12401063 0,13440903 ! proton transport GO:0015992 117 61 0,000 0,12401063 0,13434943 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,12401063 0,13428988 ! viral reproductive process GO:0022415 132 62 0,000 0,12591157 0,13628798 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,12591157 0,13622762 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,12591157 0,13616732 ! tRNA processing GO:0008033 102 62 0,000 0,12591157 0,13610706 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,12591157 0,13604687 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,12780844 0,13803538 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,12780844 0,13797438 ! hydrogen transport GO:0006818 121 64 0,000 0,12970125 0,1399559 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,12970125 0,13989411 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,12970125 0,13983237 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,13159001 0,14180608 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,13159001 0,14174356 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,13159001 0,14168109 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,13159001 0,14161867 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,13159001 0,14155631 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,13159001 0,14149401 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,13347471 0,14345742 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,13347471 0,14339434 ! gonad development GO:0008406 115 66 0,000 0,13347471 0,14333131 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,13535538 0,145287 ! activation of MAPK activity GO:0000187 124 67 0,000 0,13535538 0,14522319 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,13535538 0,14515944 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,13535538 0,14509575 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,13535538 0,14503211 ! secondary metabolic process GO:0019748 125 67 0,000 0,13535538 0,14496852 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,13535538 0,144905 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,13723203 0,14684969 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,13723203 0,1467854 ! hexose catabolic process GO:0019320 113 68 0,000 0,13723203 0,14672116 ! extracellular matrix organization GO:0030198 146 68 0,000 0,13723203 0,14665697 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,13723203 0,14659285 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,13723203 0,14652878 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,13723203 0,14646476 ! viral reproduction GO:0016032 142 68 0,000 0,13723203 0,1464008 ! regulation of lipase activity GO:0060191 137 68 0,000 0,13723203 0,1463369 ! adaptive immune response GO:0002250 126 68 0,000 0,13723203 0,14627306 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,13723203 0,14620926 ! cell projection assembly GO:0030031 138 68 0,000 0,13723203 0,14614553 ! negative regulation of cell size GO:0045792 144 69 0,000 0,13910465 0,14807523 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,13910465 0,14801074 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,13910465 0,1479463 ! lung development GO:0030324 165 69 0,000 0,13910465 0,14788192 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,13910465 0,1478176 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,13910465 0,14775333 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,13910465 0,14768912 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,13910465 0,14762496 ! developmental maturation GO:0021700 128 69 0,000 0,13910465 0,14756086 ! single fertilization GO:0007338 83 69 0,000 0,13910465 0,14749681 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,14097326 0,14941331 ! cell redox homeostasis GO:0045454 114 70 0,000 0,14097326 0,14934851 ! germ cell development GO:0007281 133 70 0,000 0,14097326 0,14928378 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,14283787 0,15119277 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,14283787 0,15112729 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,14283787 0,15106186 ! appendage morphogenesis GO:0035107 150 72 0,000 0,14469848 0,15296338 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,14469848 0,15289722 ! respiratory tube development GO:0030323 171 72 0,000 0,14469848 0,15283112 ! actin filament organization GO:0007015 167 72 0,000 0,14469848 0,15276507 ! B cell activation GO:0042113 179 72 0,000 0,14469848 0,15269908 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,14469848 0,15263315 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,14469848 0,15256728 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,14469848 0,15250146 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,14469848 0,1524357 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,14469848 0,15236999 ! appendage development GO:0048736 151 73 0,000 0,1465551 0,15425856 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,1465551 0,15419213 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,1465551 0,15412575 ! regulation of immune effector process GO:0002697 156 73 0,000 0,1465551 0,15405943 ! acute inflammatory response GO:0002526 118 74 0,000 0,14840775 0,15593984 ! amino acid transport GO:0006865 148 74 0,000 0,14840775 0,1558728 ! regulation of caspase activity GO:0043281 136 74 0,000 0,14840775 0,15580582 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,14840775 0,15573889 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,14840775 0,15567202 ! respiratory system development GO:0060541 175 74 0,000 0,14840775 0,15560521 ! organelle localization GO:0051640 155 74 0,000 0,14840775 0,15553845 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,15025643 0,15740843 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,15025643 0,15734096 ! reproductive structure development GO:0048608 131 75 0,000 0,15025643 0,15727355 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,15025643 0,15720619 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,15025643 0,15713889 ! eye development GO:0001654 155 75 0,000 0,15025643 0,15707165 ! axon guidance GO:0007411 162 75 0,000 0,15025643 0,15700447 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,15210115 0,15886409 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,15210115 0,1587962 ! learning or memory GO:0007611 161 76 0,000 0,15210115 0,15872836 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,15210115 0,15866059 ! regulation of blood pressure GO:0008217 134 76 0,000 0,15210115 0,15859287 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,15210115 0,15852521 ! amine catabolic process GO:0009310 136 77 0,000 0,15394191 0,1603753 ! neurotransmitter transport GO:0006836 142 77 0,000 0,15394191 0,16030694 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,15394191 0,16023864 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,15394191 0,16017039 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,15394191 0,16010221 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,15394191 0,16003408 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,15394191 0,15996601 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,15394191 0,15989799 ! regulation of catabolic process GO:0009894 173 77 0,000 0,15394191 0,15983004 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,15577873 0,16166841 ! antigen processing and presentation GO:0019882 117 78 0,000 0,15577873 0,16159976 ! fertilization GO:0009566 99 78 0,000 0,15577873 0,16153117 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,15577873 0,16146264 ! blood coagulation GO:0007596 151 79 0,000 0,15761161 0,16329312 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,15761161 0,16322389 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,15761161 0,16315473 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,15761161 0,16308563 ! protein oligomerization GO:0051259 149 79 0,000 0,15761161 0,16301658 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,15761161 0,1629476 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,15944057 0,16476874 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,15944057 0,16469907 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,15944057 0,16462946 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,15944057 0,16455991 ! muscle cell differentiation GO:0042692 178 81 0,000 0,1612656 0,16637326 ! response to hypoxia GO:0001666 178 81 0,000 0,1612656 0,16630303 ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,1612656 0,16623286 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,1612656 0,16616274 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,16308673 0,16796833 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,16308673 0,16789755 ! protein import into nucleus GO:0006606 174 82 0,000 0,16308673 0,16782682 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,16490395 0,16962541 ! exocytosis GO:0006887 153 83 0,000 0,16490395 0,16955402 ! response to drug GO:0042493 149 83 0,000 0,16490395 0,16948269 ! response to oxygen levels GO:0070482 183 83 0,000 0,16490395 0,16941142 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,16490395 0,16934021 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,16490395 0,16926905 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,16490395 0,16919796 ! nuclear import GO:0051170 177 83 0,000 0,16490395 0,16912693 ! response to metal ion GO:0010038 158 84 0,000 0,16671728 0,17091494 ! T cell activation GO:0042110 189 84 0,000 0,16671728 0,17084325 ! response to nutrient GO:0007584 135 84 0,000 0,16671728 0,17077162 ! digestion GO:0007586 130 84 0,000 0,16671728 0,17070005 ! regulation of ligase activity GO:0051340 147 84 0,000 0,16671728 0,17062853 ! hemostasis GO:0007599 165 85 0,000 0,16852672 0,1724082 ! negative regulation of transport GO:0051051 164 85 0,000 0,16852672 0,17233603 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,16852672 0,17226392 ! negative regulation of growth GO:0045926 168 85 0,000 0,16852672 0,17219187 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,16852672 0,17211989 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,16852672 0,17204796 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,17033228 0,17381861 ! regulation of lyase activity GO:0051339 169 86 0,000 0,17033228 0,17374604 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,17033228 0,17367352 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,17213397 0,17543734 ! mitochondrion organization GO:0007005 159 87 0,000 0,17213397 0,17536418 ! alcohol catabolic process GO:0046164 142 87 0,000 0,17213397 0,17529108 ! nucleosome assembly GO:0006334 126 87 0,000 0,17213397 0,17521804 ! regulation of protein transport GO:0051223 165 87 0,000 0,17213397 0,17514506 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,1739318 0,17690066 ! amine biosynthetic process GO:0009309 146 88 0,000 0,1739318 0,17682705 ! sensory perception of smell GO:0007608 117 88 0,000 0,1739318 0,17675349 ! chromatin assembly GO:0031497 128 88 0,000 0,1739318 0,17668 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,1739318 0,17660657 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,17572578 0,178354 ! regulation of DNA binding GO:0051101 167 89 0,000 0,17572578 0,17827993 ! cellular defense response GO:0006968 123 89 0,000 0,17572578 0,17820593 ! protein localization in nucleus GO:0034504 192 89 0,000 0,17572578 0,17813198 ! regulation of neurological system process GO:0031644 175 89 0,000 0,17572578 0,1780581 ! response to inorganic substance GO:0010035 173 90 0,000 0,17751591 0,17979742 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,17751591 0,17972291 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,17751591 0,17964846 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,17930221 0,18138107 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,17930221 0,181306 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,18108467 0,18303262 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,18286332 0,18475396 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,18286332 0,18467759 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,18286332 0,18460127 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,18286332 0,18452502 ! vitamin metabolic process GO:0006766 153 93 0,000 0,18286332 0,18444884 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,18463815 0,18616219 ! female pregnancy GO:0007565 166 94 0,000 0,18463815 0,18608539 ! sterol metabolic process GO:0016125 166 94 0,000 0,18463815 0,18600866 ! regulation of membrane potential GO:0042391 179 94 0,000 0,18463815 0,18593198 ! regulation of defense response GO:0031347 171 95 0,000 0,18640917 0,18763807 ! nucleosome organization GO:0034728 143 95 0,000 0,18640917 0,18756079 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,18640917 0,18748358 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,18640917 0,18740642 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,18640917 0,18732933 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,18640917 0,18725231 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,18640917 0,18717534 ! sex differentiation GO:0007548 171 96 0,000 0,1881764 0,1888722 ! regulation of T cell activation GO:0050863 175 96 0,000 0,1881764 0,18879464 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,18993984 0,19048564 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,18993984 0,19040748 ! transcription initiation GO:0006352 171 97 0,000 0,18993984 0,19032938 ! regulation of protein localization GO:0032880 188 97 0,000 0,18993984 0,19025134 ! leukocyte differentiation GO:0002521 232 98 0,000 0,1916995 0,1919352 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,1916995 0,19185657 ! mRNA transport GO:0051028 185 100 0,000 0,19520751 0,19528744 ! hormone metabolic process GO:0042445 171 100 0,000 0,19520751 0,19520751