pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-pos-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/88-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of translation GO:0017148 32 20 2,000 2,431E-06 5,94E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 6,935E-06 8,472E-03 ! placenta development GO:0001890 53 35 2,000 1,377E-05 0,01121027 ! spermidine metabolic process GO:0008216 7 5 1,000 1,707E-05 0,01042554 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 1,000 1,707E-05 8,34E-03 GO:0046516|hypusine metabolic process, ! enteric nervous system development GO:0048484 8 5 1,000 1,707E-05 6,95E-03 ! interaction with symbiont GO:0051702 14 6 1,000 2,558E-05 8,929E-03 ! response to exogenous dsRNA GO:0043330 13 6 1,000 2,558E-05 7,813E-03 ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 1,000 3,579E-05 9,714E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 4,768E-05 0,01164708 ! negative regulation of translational initiation GO:0045947 12 8 1,000 4,768E-05 0,01058825 ! B cell receptor signaling pathway GO:0050853 22 8 1,000 4,768E-05 9,706E-03 ! cell maturation GO:0048469 107 55 2,000 5,417E-05 0,01017911 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 1,000 6,125E-05 0,01068727 GO:0010469|regulation of receptor activity, ! pyrimidine base metabolic process GO:0006206 22 9 1,000 6,125E-05 9,975E-03 ! mitochondrion localization GO:0051646 18 9 1,000 6,125E-05 9,351E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 7,649E-05 0,01099232 ! positive regulation of phagocytosis GO:0050766 14 10 1,000 7,649E-05 0,01038164 ! response to dsRNA GO:0043331 23 10 1,000 7,649E-05 9,835E-03 ! regulation of mitosis GO:0007088 112 63 2,000 8,138E-05 9,941E-03 GO:0051783|regulation of nuclear division, ! T cell receptor signaling pathway GO:0050852 29 11 1,000 9,341E-05 0,01086683 ! developmental maturation GO:0021700 128 69 2,000 1,068E-04 0,01185759 ! polyamine metabolic process GO:0006595 18 12 1,000 1,12E-04 0,01189622 ! regulation of phagocytosis GO:0050764 17 12 1,000 1,12E-04 0,01140054 ! autonomic nervous system development GO:0048483 24 12 1,000 1,12E-04 0,01094452 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,12E-04 0,01052358 ! embryonic placenta development GO:0001892 21 12 1,000 1,12E-04 0,01013382 ! biogenic amine catabolic process GO:0042402 24 13 1,000 1,323E-04 0,01153886 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 1,777E-04 0,01497218 ! cell killing GO:0001906 32 15 1,000 1,777E-04 0,01447311 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 1,000 2,029E-04 0,01599363 ! pituitary gland development GO:0021983 30 16 1,000 2,029E-04 0,01549382 ! nucleobase metabolic process GO:0009112 43 17 1,000 2,298E-04 0,0170132 ! cellular amino acid derivative catabolic process GO:0042219 30 17 1,000 2,298E-04 0,01651281 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 1,000 2,298E-04 0,01604102 ! regulation of cell cycle process GO:0010564 161 90 2,000 2,348E-04 0,01593502 ! neural crest cell migration GO:0001755 41 18 1,000 2,583E-04 0,01705629 ! neuron maturation GO:0042551 46 19 1,000 2,885E-04 0,01854561 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 2,885E-04 0,01807008 ! response to lipopolysaccharide GO:0032496 34 19 1,000 2,885E-04 0,01761833 ! peptide cross-linking GO:0018149 39 19 1,000 2,885E-04 0,01718861 ! positive regulation of angiogenesis GO:0045766 50 20 1,000 3,203E-04 0,01862802 ! diencephalon development GO:0021536 36 21 1,000 3,537E-04 0,0200931 ! cellular response to starvation GO:0009267 37 22 1,000 3,887E-04 0,02158188 ! ureteric bud development GO:0001657 50 22 1,000 3,887E-04 0,02110229 ! gut development GO:0048565 44 22 1,000 3,887E-04 0,02064354 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 4,254E-04 0,02210989 ! response to molecule of bacterial origin GO:0002237 40 23 1,000 4,254E-04 0,02164927 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 1,000 4,636E-04 0,0231159 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! platelet activation GO:0030168 41 24 1,000 4,636E-04 0,02265359 ! interaction with host GO:0051701 66 25 1,000 5,035E-04 0,02412031 ! liver development GO:0001889 55 25 1,000 5,035E-04 0,02365646 ! positive regulation of nuclear division GO:0051785 41 26 1,000 5,45E-04 0,0251231 GO:0045840|positive regulation of mitosis, ! neural crest cell development GO:0014032 59 26 1,000 5,45E-04 0,02465786 GO:0014033|neural crest cell differentiation, ! insulin receptor signaling pathway GO:0008286 66 27 1,000 5,881E-04 0,02612428 ! response to starvation GO:0042594 47 27 1,000 5,881E-04 0,02565777 ! cellular response to nutrient levels GO:0031669 45 27 1,000 5,881E-04 0,02520763 ! acute-phase response GO:0006953 50 30 1,000 7,271E-04 0,0306241 ! immune response-activating signal transduction GO:0002757 58 30 1,000 7,271E-04 0,03010505 GO:0002764|immune response-regulating signal transduction, ! cell fate determination GO:0001709 64 30 1,000 7,271E-04 0,0296033 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 7,765E-04 0,03109992 ! metanephros development GO:0001656 81 32 1,000 8,276E-04 0,03261072 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 8,803E-04 0,03413485 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 9,345E-04 0,03567153 ! positive regulation of endocytosis GO:0045807 56 35 1,000 9,903E-04 0,03722003 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 1,107E-03 0,04096114 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 1,167E-03 0,04255559 ! mesenchymal cell development GO:0014031 94 41 1,000 1,358E-03 0,04878477 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! embryonic epithelial tube formation GO:0001838 85 41 1,000 1,358E-03 0,04807775 ! maintenance of location in cell GO:0051651 101 45 1,000 1,634E-03 0,0570236 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 1,707E-03 0,0587265 ! negative regulation of cell migration GO:0030336 122 46 1,000 1,707E-03 0,05791085 ! response to insulin stimulus GO:0032868 98 47 1,000 1,781E-03 0,05960594 ! positive regulation of cell cycle GO:0045787 96 48 1,000 1,857E-03 0,06130541 ! protein homooligomerization GO:0051260 84 49 1,000 1,934E-03 0,06300894 ! endocrine system development GO:0035270 109 50 1,000 2,013E-03 0,06471625 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 2,176E-03 0,06902608 ! regulation of angiogenesis GO:0045765 125 54 1,000 2,344E-03 0,07341337 ! regulation of translational initiation GO:0006446 87 54 1,000 2,344E-03 0,07248409 ! regulation of cell shape GO:0008360 142 54 1,000 2,344E-03 0,07157803 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 2,344E-03 0,07069436 ! negative regulation of cell motion GO:0051271 142 55 1,000 2,43E-03 0,07240651 ! positive regulation of organelle organization GO:0010638 108 58 1,000 2,698E-03 0,07942636 ! maintenance of location GO:0051235 124 58 1,000 2,698E-03 0,07848081 ! regulation of endocytosis GO:0030100 104 60 1,000 2,885E-03 0,08290759 ! kidney development GO:0001822 133 60 1,000 2,885E-03 0,08194355 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 3,275E-03 0,09195001 ! activation of MAPK activity GO:0000187 124 67 1,000 3,582E-03 0,09944714 ! urogenital system development GO:0001655 149 69 1,000 3,795E-03 0,10415854 ! activation of immune response GO:0002253 120 70 1,000 3,903E-03 0,10594168 ! acute inflammatory response GO:0002526 118 74 1,000 4,35E-03 0,11679311 ! organelle localization GO:0051640 155 74 1,000 4,35E-03 0,11552362 ! amine catabolic process GO:0009310 136 77 1,000 4,701E-03 0,12349008 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 4,701E-03 0,12217636 ! blood coagulation GO:0007596 151 79 1,000 4,942E-03 0,12708084 GO:0050817|coagulation, ! protein oligomerization GO:0051259 149 79 1,000 4,942E-03 0,12575708 ! meiosis GO:0007126 143 81 1,000 5,188E-03 0,13066421 GO:0051327|M phase of meiotic cell cycle, ! cell-substrate adhesion GO:0031589 189 82 1,000 5,313E-03 0,13245304 ! meiotic cell cycle GO:0051321 144 82 1,000 5,313E-03 0,13111513 ! hemostasis GO:0007599 165 85 1,000 5,697E-03 0,13918576 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 5,697E-03 0,13780768 ! tube morphogenesis GO:0035239 194 89 1,000 6,229E-03 0,14918075 ! gland development GO:0048732 220 91 1,000 6,502E-03 0,1542265 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 6,594E-03 0,15490574 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 6,594E-03 0,15343045 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 6,594E-03 0,15198299 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 6,594E-03 0,15056259 ! positive regulation of helicase activity GO:0051096 12 5 0,000 6,594E-03 0,1491685 ! neuron fate determination GO:0048664 7 5 0,000 6,594E-03 0,14779998 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,594E-03 0,14645634 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 6,594E-03 0,14513691 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 6,594E-03 0,14384105 ! polyol transport GO:0015791 12 5 0,000 6,594E-03 0,14256812 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 6,594E-03 0,14131752 ! response to superoxide GO:0000303 10 5 0,000 6,594E-03 0,14008867 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,594E-03 0,13888101 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 6,594E-03 0,137694 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 6,594E-03 0,1365271 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 6,594E-03 0,13537981 ! female meiosis GO:0007143 10 5 0,000 6,594E-03 0,13425165 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 6,594E-03 0,13314213 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 6,594E-03 0,1320508 ! hypothalamus development GO:0021854 9 5 0,000 6,594E-03 0,13097722 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 6,594E-03 0,12992095 ! cobalt ion transport GO:0006824 11 5 0,000 6,594E-03 0,12888158 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 6,594E-03 0,12785871 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 6,594E-03 0,12685195 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 6,594E-03 0,12586092 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 6,594E-03 0,12488525 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 6,594E-03 0,1239246 ! embryonic camera-type eye development GO:0031076 12 5 0,000 6,594E-03 0,12297861 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 6,594E-03 0,12204695 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,594E-03 0,1211293 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 6,594E-03 0,12022535 ! transposition GO:0032196 9 5 0,000 6,594E-03 0,1193348 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 6,594E-03 0,11845733 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 6,594E-03 0,11759268 ! negative chemotaxis GO:0050919 16 5 0,000 6,594E-03 0,11674056 ! positive regulation of histone modification GO:0031058 6 5 0,000 6,594E-03 0,1159007 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,594E-03 0,11507284 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 6,594E-03 0,11425672 ! behavioral response to pain GO:0048266 10 5 0,000 6,594E-03 0,11345209 ! clathrin coat assembly GO:0048268 15 5 0,000 6,594E-03 0,11265872 ! Notch receptor processing GO:0007220 11 5 0,000 6,594E-03 0,11187637 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,594E-03 0,11110481 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 6,594E-03 0,11034382 ! micturition GO:0060073 9 5 0,000 6,594E-03 0,10959318 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 6,594E-03 0,10885269 ! copulation GO:0007620 9 5 0,000 6,594E-03 0,10812213 ! glial cell fate commitment GO:0021781 14 5 0,000 6,594E-03 0,10740132 ! protein maturation by protein folding GO:0022417 14 5 0,000 6,594E-03 0,10669005 ! bioluminescence GO:0008218 9 5 0,000 6,594E-03 0,10598814 ! regulation of potassium ion transport GO:0043266 10 5 0,000 6,594E-03 0,10529541 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 6,594E-03 0,10461167 ! apoptotic cell clearance GO:0043277 23 5 0,000 6,594E-03 0,10393676 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 6,594E-03 0,1032705 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 6,594E-03 0,10261272 ! lipoprotein particle clearance GO:0034381 10 5 0,000 6,594E-03 0,10196328 ! grooming behavior GO:0007625 6 5 0,000 6,594E-03 0,101322 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 6,594E-03 0,10068873 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 6,594E-03 0,10006334 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 6,594E-03 0,09944566 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,594E-03 0,09883557 ! response to protozoan GO:0001562 13 5 0,000 6,594E-03 0,09823291 ! positive regulation of glycolysis GO:0045821 13 5 0,000 6,594E-03 0,09763756 ! lymph vessel development GO:0001945 10 5 0,000 6,594E-03 0,09704938 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 6,594E-03 0,09646825 ! endochondral ossification GO:0001958 17 5 0,000 6,594E-03 0,09589403 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 6,594E-03 0,09532661 ! single strand break repair GO:0000012 8 5 0,000 6,594E-03 0,09476587 ! parathyroid gland development GO:0060017 14 5 0,000 6,594E-03 0,09421168 ! anagen GO:0042640 7 5 0,000 6,594E-03 0,09366394 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 6,594E-03 0,09312253 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 6,594E-03 0,09258734 ! cytokine secretion GO:0050663 15 5 0,000 6,594E-03 0,09205827 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 6,594E-03 0,09153521 ! ceramide catabolic process GO:0046514 7 5 0,000 6,594E-03 0,09101806 ! skeletal myofibril assembly GO:0014866 12 5 0,000 6,594E-03 0,09050673 ! smooth muscle tissue development GO:0048745 32 5 0,000 6,594E-03 0,0900011 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,594E-03 0,0895011 ! epithelial cell proliferation GO:0050673 9 5 0,000 6,594E-03 0,08900662 ! cardiac muscle fiber development GO:0048739 12 5 0,000 6,594E-03 0,08851757 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,594E-03 0,08803387 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 6,594E-03 0,08755542 ! neutrophil mediated immunity GO:0002446 7 5 0,000 6,594E-03 0,08708215 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 6,594E-03 0,08661396 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 6,594E-03 0,08615079 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 6,594E-03 0,08569254 ! glycine biosynthetic process GO:0006545 7 5 0,000 6,594E-03 0,08523914 ! microvillus organization GO:0032528 8 5 0,000 6,594E-03 0,08479051 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 6,594E-03 0,08434658 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 6,594E-03 0,08390728 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 6,594E-03 0,08347253 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 6,594E-03 0,08304225 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 6,594E-03 0,0826164 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 6,594E-03 0,08219489 ! polyol catabolic process GO:0046174 9 5 0,000 6,594E-03 0,08177765 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 6,594E-03 0,08136463 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 6,594E-03 0,08095577 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 6,594E-03 0,08055099 ! muscle cell migration GO:0014812 8 5 0,000 6,594E-03 0,08015024 ! mitochondrial fission GO:0000266 8 5 0,000 6,594E-03 0,07975345 ! sister chromatid cohesion GO:0007062 15 5 0,000 6,594E-03 0,07936058 ! response to tumor necrosis factor GO:0034612 10 5 0,000 6,594E-03 0,07897156 ! mRNA transcription GO:0009299 10 5 0,000 6,594E-03 0,07858633 ! nerve growth factor processing GO:0032455 9 5 0,000 6,594E-03 0,07820484 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 6,594E-03 0,07782704 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 6,594E-03 0,07745287 ! anaerobic glycolysis GO:0019642 6 5 0,000 6,594E-03 0,07708228 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 6,594E-03 0,07671523 ! monocyte activation GO:0042117 10 5 0,000 6,594E-03 0,07635165 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 6,594E-03 0,0759915 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 6,594E-03 0,07563473 ! response to food GO:0032094 6 5 0,000 6,594E-03 0,0752813 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 6,594E-03 0,07493115 ! positive regulation of transporter activity GO:0032411 8 5 0,000 6,594E-03 0,07458425 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 6,594E-03 0,07424054 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,594E-03 0,07389999 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 6,594E-03 0,07356255 ! forebrain neuron development GO:0021884 13 5 0,000 6,594E-03 0,07322817 ! lipoprotein catabolic process GO:0042159 11 5 0,000 6,594E-03 0,07289682 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 6,594E-03 0,07256846 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 6,594E-03 0,07224304 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 6,594E-03 0,07192052 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,594E-03 0,07160088 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 6,594E-03 0,07128406 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 6,594E-03 0,07097003 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 6,594E-03 0,07065876 ! lipid glycosylation GO:0030259 7 5 0,000 6,594E-03 0,07035021 ! nucleobase transport GO:0015851 6 5 0,000 6,594E-03 0,07004434 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,594E-03 0,06974111 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 6,594E-03 0,06944051 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 6,594E-03 0,06914248 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 6,594E-03 0,068847 ! basic amino acid transport GO:0015802 12 5 0,000 6,594E-03 0,06855403 ! cellular glucose homeostasis GO:0001678 6 5 0,000 6,594E-03 0,06826355 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 6,594E-03 0,06797552 ! actin nucleation GO:0045010 11 5 0,000 6,594E-03 0,06768991 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,594E-03 0,06740668 ! depurination GO:0045007 5 5 0,000 6,594E-03 0,06712582 ! depyrimidination GO:0045008 10 5 0,000 6,594E-03 0,06684729 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,594E-03 0,06657106 ! regulation of centrosome cycle GO:0046605 7 5 0,000 6,594E-03 0,06629711 ! G2/M transition checkpoint GO:0031576 8 5 0,000 6,594E-03 0,0660254 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 6,594E-03 0,06575591 ! zinc ion homeostasis GO:0055069 9 5 0,000 6,594E-03 0,06548861 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 6,594E-03 0,06522347 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 6,594E-03 0,06496047 ! forebrain morphogenesis GO:0048853 13 5 0,000 6,594E-03 0,06469959 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 6,594E-03 0,06444079 ! activated T cell proliferation GO:0050798 16 5 0,000 6,594E-03 0,06418405 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 6,594E-03 0,06392936 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 6,594E-03 0,06367667 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,594E-03 0,06342597 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,594E-03 0,06317724 ! gamma-delta T cell activation GO:0046629 6 5 0,000 6,594E-03 0,06293046 ! response to arsenic GO:0046685 11 5 0,000 6,594E-03 0,06268559 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 6,594E-03 0,06244263 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 6,594E-03 0,06220153 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 6,594E-03 0,0619623 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 6,594E-03 0,06172489 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 6,594E-03 0,0614893 ! response to mercury ion GO:0046689 8 5 0,000 6,594E-03 0,0612555 ! response to cadmium ion GO:0046686 7 5 0,000 6,594E-03 0,06102348 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 6,594E-03 0,0607932 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 6,594E-03 0,06056465 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 6,594E-03 0,06033782 ! bile acid biosynthetic process GO:0006699 7 5 0,000 6,594E-03 0,06011268 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 6,594E-03 0,05988921 ! ganglioside catabolic process GO:0006689 12 5 0,000 6,594E-03 0,0596674 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 6,594E-03 0,05944722 ! decidualization GO:0046697 11 5 0,000 6,594E-03 0,05922867 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 6,594E-03 0,05901171 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 6,594E-03 0,05879634 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 6,594E-03 0,05858254 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 6,594E-03 0,05837028 ! embryonic cleavage GO:0040016 6 5 0,000 6,594E-03 0,05815956 ! peroxisome fission GO:0016559 5 5 0,000 6,594E-03 0,05795035 ! histone demethylation GO:0016577 13 5 0,000 6,594E-03 0,05774264 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 6,594E-03 0,05753642 ! mitotic recombination GO:0006312 9 5 0,000 6,594E-03 0,05733166 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 6,594E-03 0,05712836 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 6,594E-03 0,05692649 ! metaphase plate congression GO:0051310 7 5 0,000 6,594E-03 0,05672605 ! regulation of sterol transport GO:0032371 7 5 0,000 6,594E-03 0,05652701 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 6,594E-03 0,05632936 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 6,594E-03 0,05613309 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 6,594E-03 0,05593819 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 6,594E-03 0,05574463 ! muscle cell proliferation GO:0033002 12 5 0,000 6,594E-03 0,05555241 ! skeletal muscle regeneration GO:0043403 8 5 0,000 6,594E-03 0,0553615 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 6,594E-03 0,05517191 ! B cell homeostasis GO:0001782 13 5 0,000 6,594E-03 0,05498361 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 6,594E-03 0,05479659 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 6,594E-03 0,05461084 ! metaphase GO:0051323 11 5 0,000 6,594E-03 0,05442634 ! melatonin biosynthetic process GO:0030187 7 5 0,000 6,594E-03 0,05424309 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 6,594E-03 0,05406107 ! cellular response to nutrient GO:0031670 8 5 0,000 6,594E-03 0,05388026 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 6,594E-03 0,05370066 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 6,594E-03 0,05352225 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 6,594E-03 0,05334502 ! regulation of hair follicle development GO:0051797 10 5 0,000 6,594E-03 0,05316897 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 6,594E-03 0,05299407 ! response to redox state GO:0051775 6 5 0,000 6,594E-03 0,05282032 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 6,594E-03 0,0526477 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 6,594E-03 0,05247621 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,594E-03 0,05230584 ! brown fat cell differentiation GO:0050873 7 5 0,000 6,594E-03 0,05213656 ! regulation of telomerase activity GO:0051972 7 5 0,000 6,594E-03 0,05196838 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,594E-03 0,05180128 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 6,594E-03 0,05163525 ! porphyrin catabolic process GO:0006787 12 5 0,000 6,594E-03 0,05147028 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 6,594E-03 0,05130636 ! striatum development GO:0021756 14 5 0,000 6,594E-03 0,05114348 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 6,594E-03 0,05098164 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 6,594E-03 0,05082081 ! glial cell migration GO:0008347 10 5 0,000 6,594E-03 0,050661 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,594E-03 0,05050219 ! neural plate morphogenesis GO:0001839 7 5 0,000 6,594E-03 0,05034437 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 6,594E-03 0,05018753 ! somatic stem cell maintenance GO:0035019 15 5 0,000 6,594E-03 0,05003167 ! T cell activation during immune response GO:0002286 9 5 0,000 6,594E-03 0,04987677 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 6,594E-03 0,04972283 ! negative regulation of lipase activity GO:0060192 8 5 0,000 6,594E-03 0,04956984 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 6,594E-03 0,04941778 ! neuroprotection GO:0043526 8 5 0,000 6,594E-03 0,04926666 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 6,594E-03 0,04911646 ! regulation of sensory perception GO:0051931 8 5 0,000 6,594E-03 0,04896717 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 6,594E-03 0,04881878 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 6,594E-03 0,04867129 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 6,594E-03 0,04852469 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 6,594E-03 0,04837897 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 6,594E-03 0,04823412 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 6,594E-03 0,04809014 ! sequestering of calcium ion GO:0051208 7 5 0,000 6,594E-03 0,04794702 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 6,594E-03 0,04780474 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 6,594E-03 0,04766331 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 6,594E-03 0,04752271 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 6,594E-03 0,04738293 ! spindle assembly GO:0051225 6 5 0,000 6,594E-03 0,04724398 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 6,594E-03 0,04710584 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 6,594E-03 0,04696851 ! protein palmitoylation GO:0018345 12 5 0,000 6,594E-03 0,04683197 ! drug metabolic process GO:0017144 7 5 0,000 6,594E-03 0,04669622 ! stem cell division GO:0017145 11 5 0,000 6,594E-03 0,04656126 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 6,594E-03 0,04642708 ! organ regeneration GO:0031100 7 5 0,000 6,594E-03 0,04629367 ! carnitine metabolic process GO:0009437 8 5 0,000 6,594E-03 0,04616102 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 6,594E-03 0,04602914 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 6,782E-03 0,04720067 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 6,782E-03 0,04706658 ! nitrogen compound catabolic process GO:0044270 167 94 1,000 6,923E-03 0,04791337 ! biogenic amine metabolic process GO:0006576 162 97 1,000 7,356E-03 0,05076553 ! forebrain development GO:0030900 210 98 1,000 7,503E-03 0,0516339 ! positive regulation of immune response GO:0050778 175 100 1,000 7,801E-03 0,05353321 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 7,908E-03 0,05411691 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 7,908E-03 0,05396575 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 7,908E-03 0,05381542 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 7,908E-03 0,05366594 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 7,908E-03 0,05351728 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 7,908E-03 0,05336944 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 7,908E-03 0,05322242 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 7,908E-03 0,0530762 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 7,908E-03 0,05293079 ! response to oxygen radical GO:0000305 11 6 0,000 7,908E-03 0,05278617 ! positive regulation of axon extension GO:0045773 13 6 0,000 7,908E-03 0,05264233 ! myoblast cell fate commitment GO:0048625 18 6 0,000 7,908E-03 0,05249928 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 7,908E-03 0,05235701 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 7,908E-03 0,05221551 ! regulation of interferon-beta production GO:0032648 8 6 0,000 7,908E-03 0,05207476 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 7,908E-03 0,05193478 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 7,908E-03 0,05179554 ! forebrain regionalization GO:0021871 9 6 0,000 7,908E-03 0,05165705 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 7,908E-03 0,0515193 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 7,908E-03 0,05138228 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 7,908E-03 0,05124599 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 7,908E-03 0,05111041 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 7,908E-03 0,05097556 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 7,908E-03 0,05084141 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 7,908E-03 0,05070797 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 7,908E-03 0,05057523 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 7,908E-03 0,05044318 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 7,908E-03 0,05031181 ! malate metabolic process GO:0006108 13 6 0,000 7,908E-03 0,05018113 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 7,908E-03 0,05005113 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 7,908E-03 0,0499218 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 7,908E-03 0,04979314 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 7,908E-03 0,04966513 ! protein refolding GO:0042026 15 6 0,000 7,908E-03 0,04953779 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 7,908E-03 0,04941109 ! opsonization GO:0008228 8 6 0,000 7,908E-03 0,04928504 ! mating behavior GO:0007617 7 6 0,000 7,908E-03 0,04915964 ! erythrocyte maturation GO:0043249 8 6 0,000 7,908E-03 0,04903487 ! embryonic hemopoiesis GO:0035162 16 6 0,000 7,908E-03 0,04891073 ! protein amino acid dealkylation GO:0008214 15 6 0,000 7,908E-03 0,04878721 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 7,908E-03 0,04866432 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 7,908E-03 0,04854205 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 7,908E-03 0,04842039 ! response to interferon-gamma GO:0034341 16 6 0,000 7,908E-03 0,04829934 ! toxin metabolic process GO:0009404 11 6 0,000 7,908E-03 0,04817889 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 7,908E-03 0,04805905 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 7,908E-03 0,04793979 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 7,908E-03 0,04782113 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 7,908E-03 0,04770305 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 7,908E-03 0,04758556 ! cGMP-mediated signaling GO:0019934 14 6 0,000 7,908E-03 0,04746864 ! dorsal spinal cord development GO:0021516 10 6 0,000 7,908E-03 0,0473523 ! activation of MAPKKK activity GO:0000185 12 6 0,000 7,908E-03 0,04723652 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 7,908E-03 0,04712131 ! thymic T cell selection GO:0045061 16 6 0,000 7,908E-03 0,04700666 ! sphingoid catabolic process GO:0046521 8 6 0,000 7,908E-03 0,04689257 ! protein lipoylation GO:0009249 10 6 0,000 7,908E-03 0,04677902 ! transepithelial chloride transport GO:0030321 12 6 0,000 7,908E-03 0,04666603 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 7,908E-03 0,04655358 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 7,908E-03 0,04644168 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 7,908E-03 0,0463303 ! glutamate catabolic process GO:0006538 12 6 0,000 7,908E-03 0,04621947 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 7,908E-03 0,04610916 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 7,908E-03 0,04599937 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 7,908E-03 0,04589011 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 7,908E-03 0,04578137 ! hyperosmotic response GO:0006972 10 6 0,000 7,908E-03 0,04567314 ! L-serine biosynthetic process GO:0006564 7 6 0,000 7,908E-03 0,04556542 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 7,908E-03 0,0454582 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 7,908E-03 0,04535149 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 7,908E-03 0,04524529 ! urea metabolic process GO:0019627 7 6 0,000 7,908E-03 0,04513957 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 7,908E-03 0,04503435 ! neutrophil activation GO:0042119 7 6 0,000 7,908E-03 0,04492962 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 7,908E-03 0,04482538 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 7,908E-03 0,04472161 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 7,908E-03 0,04461833 ! paraxial mesoderm development GO:0048339 16 6 0,000 7,908E-03 0,04451552 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 7,908E-03 0,04441319 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 7,908E-03 0,04431132 ! neuron apoptosis GO:0051402 15 6 0,000 7,908E-03 0,04420992 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 7,908E-03 0,04410899 ! T cell mediated immunity GO:0002456 17 6 0,000 7,908E-03 0,04400851 ! negative regulation of platelet activation GO:0010544 9 6 0,000 7,908E-03 0,04390849 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 7,908E-03 0,04380893 ! carnitine transport GO:0015879 10 6 0,000 7,908E-03 0,04370981 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,908E-03 0,04361114 ! positive regulation of exocytosis GO:0045921 11 6 0,000 7,908E-03 0,04351292 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 7,908E-03 0,04341514 ! early endosome to late endosome transport GO:0045022 16 6 0,000 7,908E-03 0,0433178 ! 5S class rRNA transcription GO:0042791 13 6 0,000 7,908E-03 0,04322089 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 7,908E-03 0,04312441 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 7,908E-03 0,04302837 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 7,908E-03 0,04293275 ! sodium ion homeostasis GO:0055078 12 6 0,000 7,908E-03 0,04283755 ! establishment of spindle localization GO:0051293 16 6 0,000 7,908E-03 0,04274278 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 7,908E-03 0,04264843 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 7,908E-03 0,04255449 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 7,908E-03 0,04246096 ! response to UV-C GO:0010225 14 6 0,000 7,908E-03 0,04236784 ! astrocyte development GO:0014002 16 6 0,000 7,908E-03 0,04227514 ! protein targeting to lysosome GO:0006622 12 6 0,000 7,908E-03 0,04218283 ! purine base biosynthetic process GO:0009113 17 6 0,000 7,908E-03 0,04209093 ! regulation of dendrite development GO:0050773 16 6 0,000 7,908E-03 0,04199943 ! peptidyl-arginine modification GO:0018195 13 6 0,000 7,908E-03 0,04190832 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 7,908E-03 0,04181761 ! response to copper ion GO:0046688 10 6 0,000 7,908E-03 0,04172729 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 7,908E-03 0,04163736 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,908E-03 0,04154782 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 7,908E-03 0,04145866 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 7,908E-03 0,04136989 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 7,908E-03 0,04128149 ! regulation of dopamine secretion GO:0014059 14 6 0,000 7,908E-03 0,04119347 ! nucleoside catabolic process GO:0009164 10 6 0,000 7,908E-03 0,04110582 ! hair follicle maturation GO:0048820 8 6 0,000 7,908E-03 0,04101855 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 7,908E-03 0,04093165 ! Schwann cell development GO:0014044 15 6 0,000 7,908E-03 0,04084511 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 7,908E-03 0,04075894 ! response to pheromone GO:0019236 6 6 0,000 7,908E-03 0,04067313 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 7,908E-03 0,04058768 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 7,908E-03 0,04050259 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 7,908E-03 0,04041786 ! base conversion or substitution editing GO:0016553 6 6 0,000 7,908E-03 0,04033348 ! subpallium development GO:0021544 15 6 0,000 7,908E-03 0,04024945 ! neural tube patterning GO:0021532 8 6 0,000 7,908E-03 0,04016577 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 7,908E-03 0,04008244 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 7,908E-03 0,03999946 ! maintenance of organ identity GO:0048496 9 6 0,000 7,908E-03 0,03991681 ! G2 phase GO:0051319 16 6 0,000 7,908E-03 0,03983451 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 7,908E-03 0,03975254 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 7,908E-03 0,03967092 ! oxygen homeostasis GO:0032364 10 6 0,000 7,908E-03 0,03958962 ! establishment of planar polarity GO:0001736 7 6 0,000 7,908E-03 0,03950866 ! regulation of mast cell activation GO:0033003 13 6 0,000 7,908E-03 0,03942803 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 7,908E-03 0,03934773 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 7,908E-03 0,03926776 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 7,908E-03 0,03918811 ! receptor internalization GO:0031623 11 6 0,000 7,908E-03 0,03910878 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 7,908E-03 0,03902977 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 7,908E-03 0,03895108 ! neutrophil homeostasis GO:0001780 11 6 0,000 7,908E-03 0,03887271 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 7,908E-03 0,03879465 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 7,908E-03 0,03871691 ! protein deubiquitination GO:0016579 16 6 0,000 7,908E-03 0,03863947 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 7,908E-03 0,03856235 ! protein destabilization GO:0031648 9 6 0,000 7,908E-03 0,03848553 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 7,908E-03 0,03840902 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 7,908E-03 0,03833281 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 7,908E-03 0,0382569 ! regulation of viral transcription GO:0046782 11 6 0,000 7,908E-03 0,0381813 ! progesterone metabolic process GO:0042448 12 6 0,000 7,908E-03 0,03810599 ! negative regulation of axon extension GO:0030517 24 6 0,000 7,908E-03 0,03803098 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 7,908E-03 0,03795626 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 7,908E-03 0,03788184 ! triglyceride catabolic process GO:0019433 10 6 0,000 7,908E-03 0,0378077 ! determination of adult lifespan GO:0008340 17 6 0,000 7,908E-03 0,03773386 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 7,908E-03 0,03766031 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 7,908E-03 0,03758704 ! neural plate development GO:0001840 9 6 0,000 7,908E-03 0,03751405 ! catecholamine transport GO:0051937 9 6 0,000 7,908E-03 0,03744135 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 7,908E-03 0,03736893 ! sensory cilium assembly GO:0035058 10 6 0,000 7,908E-03 0,03729679 ! organ or tissue specific immune response GO:0002251 8 6 0,000 7,908E-03 0,03722493 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 7,908E-03 0,03715334 ! maternal placenta development GO:0001893 12 6 0,000 7,908E-03 0,03708203 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 7,908E-03 0,03701099 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 7,908E-03 0,03694022 ! negative regulation of B cell activation GO:0050869 14 6 0,000 7,908E-03 0,03686973 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 7,908E-03 0,0367995 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 7,908E-03 0,03672954 ! positive regulation of coagulation GO:0050820 13 6 0,000 7,908E-03 0,03665984 ! cellular anion homeostasis GO:0030002 11 6 0,000 7,908E-03 0,03659041 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 9,22E-03 0,04258057 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 9,22E-03 0,04250023 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 9,22E-03 0,04242019 ! behavioral response to cocaine GO:0048148 14 7 0,000 9,22E-03 0,04234045 ! regulation of helicase activity GO:0051095 16 7 0,000 9,22E-03 0,04226102 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 9,22E-03 0,04218188 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 9,22E-03 0,04210303 ! sleep GO:0030431 16 7 0,000 9,22E-03 0,04202448 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 9,22E-03 0,04194622 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 9,22E-03 0,04186826 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 9,22E-03 0,04179058 ! prostate gland development GO:0030850 14 7 0,000 9,22E-03 0,04171319 ! nucleotide-sugar transport GO:0015780 11 7 0,000 9,22E-03 0,04163608 ! synaptonemal complex assembly GO:0007130 10 7 0,000 9,22E-03 0,04155927 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 9,22E-03 0,04148273 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 9,22E-03 0,04140647 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 9,22E-03 0,0413305 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 9,22E-03 0,0412548 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 9,22E-03 0,04117938 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 9,22E-03 0,04110424 ! SMAD protein complex assembly GO:0007183 13 7 0,000 9,22E-03 0,04102937 ! glycolipid transport GO:0046836 11 7 0,000 9,22E-03 0,04095477 ! protein amino acid sulfation GO:0006477 10 7 0,000 9,22E-03 0,04088044 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 9,22E-03 0,04080638 ! neuron adhesion GO:0007158 14 7 0,000 9,22E-03 0,04073259 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 9,22E-03 0,04065906 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 9,22E-03 0,04058581 ! establishment of tissue polarity GO:0007164 8 7 0,000 9,22E-03 0,04051281 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 9,22E-03 0,04044008 ! mRNA stabilization GO:0048255 18 7 0,000 9,22E-03 0,0403676 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 9,22E-03 0,04029539 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 9,22E-03 0,04022343 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 9,22E-03 0,04015173 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 9,22E-03 0,04008029 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 9,22E-03 0,0400091 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 9,22E-03 0,03993816 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 9,22E-03 0,03986747 ! lipoprotein transport GO:0042953 14 7 0,000 9,22E-03 0,03979704 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 9,22E-03 0,03972685 ! rhythmic behavior GO:0007622 17 7 0,000 9,22E-03 0,0396569 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 9,22E-03 0,03958721 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 9,22E-03 0,03951776 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 9,22E-03 0,03944855 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 9,22E-03 0,03937958 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 9,22E-03 0,03931086 ! regulation of odontogenesis GO:0042481 14 7 0,000 9,22E-03 0,03924237 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 9,22E-03 0,03917413 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 9,22E-03 0,03910611 ! mechanosensory behavior GO:0007638 16 7 0,000 9,22E-03 0,03903834 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 9,22E-03 0,0389708 ! positive regulation of isotype switching GO:0045830 17 7 0,000 9,22E-03 0,03890349 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 9,22E-03 0,03883642 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 9,22E-03 0,03876957 ! protein-cofactor linkage GO:0018065 13 7 0,000 9,22E-03 0,03870296 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 9,22E-03 0,03863657 ! spinal cord patterning GO:0021511 14 7 0,000 9,22E-03 0,03857041 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 9,22E-03 0,03850448 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 9,22E-03 0,03843877 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 9,22E-03 0,03837329 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 9,22E-03 0,03830803 ! adrenal gland development GO:0030325 17 7 0,000 9,22E-03 0,03824299 ! cysteine metabolic process GO:0006534 13 7 0,000 9,22E-03 0,03817817 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 9,22E-03 0,03811357 ! ovulation GO:0030728 10 7 0,000 9,22E-03 0,03804919 ! adenohypophysis development GO:0021984 11 7 0,000 9,22E-03 0,03798503 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 9,22E-03 0,03792108 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 9,22E-03 0,03785735 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 9,22E-03 0,03779383 ! microtubule nucleation GO:0007020 21 7 0,000 9,22E-03 0,03773052 ! proline biosynthetic process GO:0006561 10 7 0,000 9,22E-03 0,03766743 ! tryptophan metabolic process GO:0006568 11 7 0,000 9,22E-03 0,03760454 ! thyroid hormone generation GO:0006590 13 7 0,000 9,22E-03 0,03754187 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 9,22E-03 0,0374794 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 9,22E-03 0,03741715 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 9,22E-03 0,03735509 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 9,22E-03 0,03729325 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 9,22E-03 0,03723161 ! galactose metabolic process GO:0006012 13 7 0,000 9,22E-03 0,03717017 ! vesicle fusion GO:0006906 20 7 0,000 9,22E-03 0,03710893 ! response to dietary excess GO:0002021 8 7 0,000 9,22E-03 0,0370479 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 9,22E-03 0,03698706 ! intracellular pH reduction GO:0051452 13 7 0,000 9,22E-03 0,03692643 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 9,22E-03 0,03686599 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 9,22E-03 0,03680575 ! organ growth GO:0035265 15 7 0,000 9,22E-03 0,03674571 ! nucleoside transport GO:0015858 11 7 0,000 9,22E-03 0,03668587 ! nucleoside salvage GO:0043174 11 7 0,000 9,22E-03 0,03662621 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 9,22E-03 0,03656676 ! male sex determination GO:0030238 15 7 0,000 9,22E-03 0,03650749 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 9,22E-03 0,03644842 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 9,22E-03 0,03638953 ! parturition GO:0007567 16 7 0,000 9,22E-03 0,03633084 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 9,22E-03 0,03627234 ! rRNA modification GO:0000154 14 7 0,000 9,22E-03 0,03621402 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 9,22E-03 0,03615589 ! spindle checkpoint GO:0031577 16 7 0,000 9,22E-03 0,03609795 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 9,22E-03 0,0360402 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 9,22E-03 0,03598262 ! monocyte differentiation GO:0030224 16 7 0,000 9,22E-03 0,03592523 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 9,22E-03 0,03586803 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 9,22E-03 0,035811 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 9,22E-03 0,03575416 ! hyaluronan metabolic process GO:0030212 9 7 0,000 9,22E-03 0,0356975 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 9,22E-03 0,03564102 ! anterograde axon cargo transport GO:0008089 18 7 0,000 9,22E-03 0,03558471 ! fibrinolysis GO:0042730 11 7 0,000 9,22E-03 0,03552858 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 9,22E-03 0,03547263 ! skeletal muscle contraction GO:0003009 8 7 0,000 9,22E-03 0,03541686 ! eating behavior GO:0042755 8 7 0,000 9,22E-03 0,03536126 ! B cell lineage commitment GO:0002326 21 7 0,000 9,22E-03 0,03530583 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 9,22E-03 0,03525058 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 9,22E-03 0,0351955 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 9,22E-03 0,0351406 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 9,22E-03 0,03508586 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 9,22E-03 0,03503129 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 9,22E-03 0,0349769 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 9,22E-03 0,03492267 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 9,22E-03 0,03486861 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 9,22E-03 0,03481472 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 9,22E-03 0,03476099 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 9,22E-03 0,03470743 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 9,22E-03 0,03465403 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 9,22E-03 0,0346008 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 9,22E-03 0,03454773 ! histone ubiquitination GO:0016574 9 7 0,000 9,22E-03 0,03449483 ! regulation of meiosis GO:0040020 12 7 0,000 9,22E-03 0,03444208 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 9,22E-03 0,0343895 ! T cell lineage commitment GO:0002360 16 7 0,000 9,22E-03 0,03433708 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 9,22E-03 0,03428481 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 9,22E-03 0,03423271 ! membrane to membrane docking GO:0022614 14 7 0,000 9,22E-03 0,03418076 ! transcription termination GO:0006353 14 7 0,000 9,22E-03 0,03412897 ! coenzyme A metabolic process GO:0015936 12 7 0,000 9,22E-03 0,03407734 ! anaphase GO:0051322 18 7 0,000 9,22E-03 0,03402586 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 9,22E-03 0,03397454 ! axonal fasciculation GO:0007413 19 7 0,000 9,22E-03 0,03392338 ! negative regulation of nuclear division GO:0051784 15 7 0,000 9,22E-03 0,03387236 GO:0045839|negative regulation of mitosis, ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 9,22E-03 0,0338215 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 9,22E-03 0,0337708 ! diuresis GO:0030146 12 7 0,000 9,22E-03 0,03372024 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 9,22E-03 0,03366984 ! thiamin metabolic process GO:0006772 7 7 0,000 9,22E-03 0,03361958 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 9,22E-03 0,03356948 ! antibiotic transport GO:0042891 9 7 0,000 9,22E-03 0,03351953 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 9,22E-03 0,03346972 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 9,22E-03 0,03342006 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 9,22E-03 0,03337055 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 9,22E-03 0,03332119 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 9,22E-03 0,03327197 ! melanin biosynthetic process GO:0042438 10 7 0,000 9,22E-03 0,03322289 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 9,22E-03 0,03317396 ! dopamine biosynthetic process GO:0042416 18 7 0,000 9,22E-03 0,03312518 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 9,22E-03 0,03307654 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 9,22E-03 0,03302804 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 9,22E-03 0,03297968 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 9,22E-03 0,03293146 ! endosome to lysosome transport GO:0008333 12 7 0,000 9,22E-03 0,03288339 ! protein modification by small protein removal GO:0070646 19 7 0,000 9,22E-03 0,03283545 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 9,22E-03 0,03278766 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 9,22E-03 0,03274 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 9,22E-03 0,03269248 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 9,22E-03 0,0326451 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 9,22E-03 0,03259786 ! muscle adaptation GO:0043500 13 7 0,000 9,22E-03 0,03255075 ! embryonic heart tube development GO:0035050 14 7 0,000 9,22E-03 0,03250378 ! retina homeostasis GO:0001895 12 7 0,000 9,22E-03 0,03245695 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 9,22E-03 0,03241025 ! protein amino acid prenylation GO:0018346 19 7 0,000 9,22E-03 0,03236368 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 9,22E-03 0,03231725 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 9,22E-03 0,03227095 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01053064 0,03680452 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01053064 0,03675194 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,01053064 0,03669951 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01053064 0,03664723 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01053064 0,0365951 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01053064 0,03654312 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01053064 0,03649129 ! male meiosis GO:0007140 9 8 0,000 0,01053064 0,0364396 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01053064 0,03638806 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01053064 0,03633666 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01053064 0,03628541 ! meiotic prophase I GO:0007128 14 8 0,000 0,01053064 0,03623431 ! response to zinc ion GO:0010043 12 8 0,000 0,01053064 0,03618334 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,01053064 0,03613252 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01053064 0,03608185 ! oligopeptide transport GO:0006857 16 8 0,000 0,01053064 0,03603131 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01053064 0,03598092 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01053064 0,03593067 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01053064 0,03588055 ! signal peptide processing GO:0006465 12 8 0,000 0,01053064 0,03583058 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01053064 0,03578075 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01053064 0,03573105 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01053064 0,03568149 ! succinate metabolic process GO:0006105 17 8 0,000 0,01053064 0,03563207 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01053064 0,03558279 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01053064 0,03553364 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01053064 0,03548463 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01053064 0,03543575 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01053064 0,03538701 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01053064 0,0353384 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01053064 0,03528993 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01053064 0,03524159 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01053064 0,03519338 ! reflex GO:0060004 17 8 0,000 0,01053064 0,0351453 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01053064 0,03509735 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01053064 0,03504953 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01053064 0,03500185 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01053064 0,03495429 ! pigment granule organization GO:0048753 17 8 0,000 0,01053064 0,03490686 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01053064 0,03485956 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01053064 0,03481239 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01053064 0,03476535 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01053064 0,03471843 ! histidine catabolic process GO:0006548 10 8 0,000 0,01053064 0,03467164 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01053064 0,03462498 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01053064 0,03457844 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01053064 0,03453202 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,01053064 0,03448573 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01053064 0,03443957 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01053064 0,03439353 ! melanin metabolic process GO:0006582 17 8 0,000 0,01053064 0,03434761 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01053064 0,03430181 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01053064 0,03425614 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01053064 0,03421058 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01053064 0,03416515 ! macrophage activation GO:0042116 13 8 0,000 0,01053064 0,03411984 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01053064 0,03407465 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01053064 0,03402957 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01053064 0,03398462 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01053064 0,03393979 ! purine salvage GO:0043101 12 8 0,000 0,01053064 0,03389507 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01053064 0,03385047 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01053064 0,03380599 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01053064 0,03376162 ! osteoblast development GO:0002076 17 8 0,000 0,01053064 0,03371738 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01053064 0,03367324 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01053064 0,03362923 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01053064 0,03358532 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01053064 0,03354154 ! response to UV-B GO:0010224 17 8 0,000 0,01053064 0,03349786 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01053064 0,0334543 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01053064 0,03341085 ! intermediate filament organization GO:0045109 12 8 0,000 0,01053064 0,03336752 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01053064 0,0333243 ! cellular extravasation GO:0045123 13 8 0,000 0,01053064 0,03328119 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01053064 0,03323819 ! response to antibiotic GO:0046677 11 8 0,000 0,01053064 0,0331953 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01053064 0,03315252 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01053064 0,03310986 ! DNA topological change GO:0006265 12 8 0,000 0,01053064 0,0330673 ! response to tropane GO:0014073 15 8 0,000 0,01053064 0,03302485 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01053064 0,03298251 ! melanosome transport GO:0032402 13 8 0,000 0,01053064 0,03294028 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 0,01053064 0,03289816 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01053064 0,03285614 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01053064 0,03281423 ! mast cell activation GO:0045576 14 8 0,000 0,01053064 0,03277243 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01053064 0,03273074 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01053064 0,03268915 ! gas homeostasis GO:0033483 14 8 0,000 0,01053064 0,03264766 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01053064 0,03260628 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01053064 0,03256501 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01053064 0,03252384 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01053064 0,03248277 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01053064 0,03244181 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01053064 0,03240095 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01053064 0,0323602 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01053064 0,03231954 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01053064 0,03227899 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01053064 0,03223854 ! response to tumor cell GO:0002347 16 8 0,000 0,01053064 0,03219819 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01053064 0,03215795 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,01053064 0,0321178 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01053064 0,03207775 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01053064 0,03203781 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01053064 0,03199796 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01053064 0,03195821 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01053064 0,03191856 ! hormone catabolic process GO:0042447 17 8 0,000 0,01053064 0,03187901 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01053064 0,03183955 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01053064 0,03180019 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01053064 0,03176094 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01053064 0,03172177 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01053064 0,03168271 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01053064 0,03164374 ! adult feeding behavior GO:0008343 10 8 0,000 0,01053064 0,03160486 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01053064 0,03156608 ! ATP catabolic process GO:0006200 11 8 0,000 0,01053064 0,0315274 ! blastocyst growth GO:0001832 19 8 0,000 0,01053064 0,03148881 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01053064 0,03145032 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01053064 0,03141191 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01053064 0,03137361 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01053064 0,03133539 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01053064 0,03129727 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01053064 0,03125924 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01053064 0,03122131 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01053064 0,03118346 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01053064 0,03114571 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01053064 0,03110805 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01053064 0,03107048 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01053064 0,031033 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01053064 0,03099561 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01053064 0,03095831 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01053064 0,0309211 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01053064 0,03088398 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01053064 0,03084695 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,01053064 0,03081001 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,01053064 0,03077316 ! axon extension GO:0048675 16 9 0,000 0,01183932 0,03455609 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01183932 0,03451486 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01183932 0,03447372 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,01183932 0,03443268 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01183932 0,03439174 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01183932 0,03435089 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01183932 0,03431014 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01183932 0,03426949 ! reproductive behavior GO:0019098 22 9 0,000 0,01183932 0,03422893 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01183932 0,03418847 ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01183932 0,03414811 ! UTP metabolic process GO:0046051 10 9 0,000 0,01183932 0,03410784 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01183932 0,03406767 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01183932 0,03402759 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01183932 0,0339876 ! artery development GO:0060840 25 9 0,000 0,01183932 0,03394771 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01183932 0,03390791 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01183932 0,03386821 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01183932 0,0338286 ! equilibrioception GO:0050957 20 9 0,000 0,01183932 0,03378908 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01183932 0,03374965 ! chemosensory behavior GO:0007635 21 9 0,000 0,01183932 0,03371031 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01183932 0,03367107 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01183932 0,03363192 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01183932 0,03359286 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01183932 0,03355389 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01183932 0,03351501 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01183932 0,03347621 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01183932 0,03343751 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01183932 0,0333989 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01183932 0,03336038 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01183932 0,03332195 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01183932 0,0332836 ! protein targeting to ER GO:0045047 25 9 0,000 0,01183932 0,03324534 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01183932 0,03320718 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01183932 0,03316909 ! T cell selection GO:0045058 27 9 0,000 0,01183932 0,0331311 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,01183932 0,03309319 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01183932 0,03305537 ! glycine catabolic process GO:0006546 15 9 0,000 0,01183932 0,03301764 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01183932 0,03297999 ! endosome organization GO:0007032 20 9 0,000 0,01183932 0,03294243 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01183932 0,03290495 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01183932 0,03286756 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01183932 0,03283025 ! mannose metabolic process GO:0006013 13 9 0,000 0,01183932 0,03279303 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01183932 0,03275589 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01183932 0,03271883 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01183932 0,03268186 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01183932 0,03264498 ! receptor clustering GO:0043113 20 9 0,000 0,01183932 0,03260817 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01183932 0,03257145 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01183932 0,03253481 ! retinol metabolic process GO:0042572 20 9 0,000 0,01183932 0,03249826 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01183932 0,03246178 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01183932 0,03242539 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01183932 0,03238908 ! macrophage differentiation GO:0030225 15 9 0,000 0,01183932 0,03235285 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01183932 0,0323167 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01183932 0,03228064 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01183932 0,03224465 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01183932 0,03220874 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01183932 0,03217291 ! response to amine stimulus GO:0014075 13 9 0,000 0,01183932 0,03213717 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01183932 0,0321015 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01183932 0,03206591 ! erythrocyte development GO:0048821 17 9 0,000 0,01183932 0,0320304 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01183932 0,03199497 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01183932 0,03195961 ! renal water homeostasis GO:0003091 15 9 0,000 0,01183932 0,03192434 ! postreplication repair GO:0006301 25 9 0,000 0,01183932 0,03188914 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01183932 0,03185402 ! icosanoid secretion GO:0032309 15 9 0,000 0,01183932 0,03181898 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01183932 0,03178401 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01183932 0,03174912 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01183932 0,03171431 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01183932 0,03167957 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01183932 0,03164491 ! sterol catabolic process GO:0016127 14 9 0,000 0,01183932 0,03161033 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01183932 0,03157582 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01183932 0,03154138 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01183932 0,03150703 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01183932 0,03147274 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01183932 0,03143853 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01183932 0,0314044 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01183932 0,03137034 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01183932 0,03133635 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01183932 0,03130243 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01183932 0,03126859 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01183932 0,03123483 ! purine base metabolic process GO:0006144 25 9 0,000 0,01183932 0,03120113 ! pigment granule transport GO:0051904 17 9 0,000 0,01183932 0,03116751 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01183932 0,03113396 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01183932 0,03110048 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01183932 0,03106708 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01183932 0,03103374 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01183932 0,03100048 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,0131463 0,03438587 ! regulation of developmental growth GO:0048638 16 10 0,000 0,0131463 0,03434909 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,0131463 0,0343124 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,0131463 0,03427578 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0131463 0,03423924 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,0131463 0,03420277 ! associative learning GO:0008306 21 10 0,000 0,0131463 0,03416639 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,0131463 0,03413008 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0131463 0,03409385 ! phosphate transport GO:0006817 24 10 0,000 0,0131463 0,03405769 ! cell volume homeostasis GO:0006884 17 10 0,000 0,0131463 0,03402161 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,0131463 0,03398561 ! CTP metabolic process GO:0046036 11 10 0,000 0,0131463 0,03394969 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,0131463 0,03391384 ! GTP metabolic process GO:0046039 11 10 0,000 0,0131463 0,03387806 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,0131463 0,03384236 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,0131463 0,03380674 ! social behavior GO:0035176 29 10 0,000 0,0131463 0,03377119 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,0131463 0,03373572 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,0131463 0,03370032 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,0131463 0,03366499 ! androgen metabolic process GO:0008209 17 10 0,000 0,0131463 0,03362974 ! phospholipid efflux GO:0033700 19 10 0,000 0,0131463 0,03359456 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0131463 0,03355946 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,0131463 0,03352443 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,0131463 0,03348947 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,0131463 0,03345459 ! lung alveolus development GO:0048286 26 10 0,000 0,0131463 0,03341977 ! pathogenesis GO:0009405 17 10 0,000 0,0131463 0,03338503 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0131463 0,03335037 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,0131463 0,03331577 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,0131463 0,03328125 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,0131463 0,03324679 ! endoderm development GO:0007492 18 10 0,000 0,0131463 0,03321241 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,0131463 0,0331781 ! arginine catabolic process GO:0006527 17 10 0,000 0,0131463 0,03314386 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0131463 0,03310969 ! proline metabolic process GO:0006560 13 10 0,000 0,0131463 0,0330756 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,0131463 0,03304157 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,0131463 0,03300761 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,0131463 0,03297372 ! V(D)J recombination GO:0033151 34 10 0,000 0,0131463 0,0329399 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,0131463 0,03290615 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,0131463 0,03287247 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,0131463 0,03283886 ! B cell proliferation GO:0042100 19 10 0,000 0,0131463 0,03280531 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,0131463 0,03277184 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,0131463 0,03273843 ! multicellular organism growth GO:0035264 19 10 0,000 0,0131463 0,03270509 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,0131463 0,03267182 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,0131463 0,03263862 ! ruffle organization GO:0031529 17 10 0,000 0,0131463 0,03260549 ! epithelial cell development GO:0002064 21 10 0,000 0,0131463 0,03257242 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,0131463 0,03253942 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0131463 0,03250648 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,0131463 0,03247361 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,0131463 0,03244081 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,0131463 0,03240808 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,0131463 0,03237541 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,0131463 0,0323428 ! motor axon guidance GO:0008045 22 10 0,000 0,0131463 0,03231026 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0131463 0,03227779 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0131463 0,03224538 ! protein heterooligomerization GO:0051291 17 10 0,000 0,0131463 0,03221304 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0131463 0,03218076 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0131463 0,03214855 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,0131463 0,0321164 ! segment specification GO:0007379 15 10 0,000 0,0131463 0,03208432 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,0131463 0,0320523 ! blastoderm segmentation GO:0007350 19 10 0,000 0,0131463 0,03202034 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,0131463 0,03198845 ! DNA ligation GO:0006266 18 10 0,000 0,0131463 0,03195662 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,0131463 0,03192485 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0131463 0,03189315 ! melanosome localization GO:0032400 16 10 0,000 0,0131463 0,03186151 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,0131463 0,03182993 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,0131463 0,03179842 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,0131463 0,03176697 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0131463 0,03173558 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,0131463 0,03170425 ! induction of an organ GO:0001759 17 10 0,000 0,0131463 0,03167298 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,0131463 0,03164178 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,0131463 0,03161063 ! protein sumoylation GO:0016925 17 10 0,000 0,0131463 0,03157955 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,0131463 0,03154853 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0131463 0,03151757 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0131463 0,03148667 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0131463 0,03145583 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,0131463 0,03142505 ! salivary gland development GO:0007431 28 10 0,000 0,0131463 0,03139433 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,0131463 0,03136367 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,0131463 0,03133308 ! midbrain development GO:0030901 14 10 0,000 0,0131463 0,03130254 ! musculoskeletal movement GO:0050881 16 10 0,000 0,0131463 0,03127206 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,0131463 0,03124164 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,0131463 0,03121128 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,0131463 0,03118097 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,0131463 0,03115073 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,0131463 0,03112055 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0131463 0,03109042 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0131463 0,03106035 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,0131463 0,03103034 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,0131463 0,03100039 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,0131463 0,03097049 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0131463 0,03094066 ! blastocyst formation GO:0001825 18 10 0,000 0,0131463 0,03091088 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,0131463 0,03088116 ! cerebellar cortex development GO:0021695 16 10 0,000 0,0131463 0,03085149 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,0131463 0,03082188 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,0131463 0,03079233 ! response to nicotine GO:0035094 20 10 0,000 0,0131463 0,03076284 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,0131463 0,0307334 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,0131463 0,03070402 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01445159 0,03372037 ! respiratory burst GO:0045730 17 11 0,000 0,01445159 0,03368819 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01445159 0,03365608 ! neuron fate specification GO:0048665 18 11 0,000 0,01445159 0,03362402 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01445159 0,03359203 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01445159 0,0335601 ! thyroid gland development GO:0030878 26 11 0,000 0,01445159 0,03352823 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,01445159 0,03349642 ! synapsis GO:0007129 14 11 0,000 0,01445159 0,03346467 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01445159 0,03343298 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,01445159 0,03340135 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,01445159 0,03336978 ! response to pain GO:0048265 27 11 0,000 0,01445159 0,03333827 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01445159 0,03330681 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,01445159 0,03327542 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01445159 0,03324409 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01445159 0,03321282 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01445159 0,0331816 ! bone resorption GO:0045453 16 11 0,000 0,01445159 0,03315044 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01445159 0,03311935 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,01445159 0,03308831 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01445159 0,03305732 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01445159 0,0330264 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01445159 0,03299554 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01445159 0,03296473 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01445159 0,03293398 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01445159 0,03290328 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01445159 0,03287265 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01445159 0,03284207 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01445159 0,03281155 ! UV protection GO:0009650 20 11 0,000 0,01445159 0,03278108 ! adult heart development GO:0007512 16 11 0,000 0,01445159 0,03275067 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01445159 0,03272032 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01445159 0,03269002 ! macroautophagy GO:0016236 19 11 0,000 0,01445159 0,03265978 ! temperature homeostasis GO:0001659 18 11 0,000 0,01445159 0,0326296 ! behavioral fear response GO:0001662 27 11 0,000 0,01445159 0,03259947 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01445159 0,03256939 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01445159 0,03253938 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01445159 0,03250941 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01445159 0,03247951 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01445159 0,03244965 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01445159 0,03241986 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01445159 0,03239011 ! regulation of organ growth GO:0046620 14 11 0,000 0,01445159 0,03236042 ! pigment granule localization GO:0051875 20 11 0,000 0,01445159 0,03233079 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01445159 0,03230121 ! vasoconstriction GO:0042310 20 11 0,000 0,01445159 0,03227168 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01445159 0,03224221 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01445159 0,03221279 ! embryonic axis specification GO:0000578 19 11 0,000 0,01445159 0,03218343 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01445159 0,03215412 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01445159 0,03212486 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,01445159 0,03209566 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01445159 0,03206651 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01445159 0,03203741 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01445159 0,03200836 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01445159 0,03197937 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01445159 0,03195043 ! prophase GO:0051324 17 11 0,000 0,01445159 0,03192154 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01445159 0,0318927 ! nucleosome positioning GO:0016584 15 11 0,000 0,01445159 0,03186392 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01445159 0,03183519 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01445159 0,03180651 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01445159 0,03177788 ! apical protein localization GO:0045176 18 11 0,000 0,01445159 0,0317493 ! acid secretion GO:0046717 20 11 0,000 0,01445159 0,03172078 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01445159 0,0316923 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01445159 0,03166388 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01445159 0,0316355 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01445159 0,03160718 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01445159 0,03157891 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01445159 0,03155069 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01445159 0,03152252 ! cholesterol efflux GO:0033344 21 11 0,000 0,01445159 0,0314944 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01445159 0,03146633 ! oocyte development GO:0048599 20 11 0,000 0,01445159 0,03143831 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01445159 0,03141034 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01445159 0,03138242 ! embryonic gut development GO:0048566 19 11 0,000 0,01445159 0,03135455 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01445159 0,03132673 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,01445159 0,03129896 ! activation of innate immune response GO:0002218 16 11 0,000 0,01445159 0,03127123 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,01445159 0,03124356 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01445159 0,03121594 ! lysogeny GO:0030069 22 11 0,000 0,01445159 0,03118836 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01445159 0,03116083 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01445159 0,03113335 ! regulation of embryonic development GO:0045995 35 11 0,000 0,01445159 0,03110592 ! nucleus localization GO:0051647 22 11 0,000 0,01445159 0,03107854 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01575518 0,03385217 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01575518 0,03382242 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,01575518 0,03379273 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01575518 0,03376308 ! virus-host interaction GO:0019048 30 12 0,000 0,01575518 0,03373349 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,01575518 0,03370395 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01575518 0,03367447 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01575518 0,03364503 ! protein complex disassembly GO:0043241 28 12 0,000 0,01575518 0,03361565 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01575518 0,03358631 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,01575518 0,03355703 ! hippocampus development GO:0021766 29 12 0,000 0,01575518 0,0335278 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,01575518 0,03349862 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01575518 0,03346949 ! T cell proliferation GO:0042098 32 12 0,000 0,01575518 0,03344041 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01575518 0,03341138 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01575518 0,03338241 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01575518 0,03335348 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01575518 0,0333246 ! drug transport GO:0015893 16 12 0,000 0,01575518 0,03329577 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01575518 0,033267 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01575518 0,03323827 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01575518 0,03320959 ! focal adhesion formation GO:0048041 37 12 0,000 0,01575518 0,03318096 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01575518 0,03315238 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,01575518 0,03312385 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01575518 0,03309537 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01575518 0,03306694 ! lipid digestion GO:0044241 21 12 0,000 0,01575518 0,03303855 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01575518 0,03301022 ! entry into host cell GO:0030260 34 12 0,000 0,01575518 0,03298193 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01575518 0,03295369 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01575518 0,0329255 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01575518 0,03289736 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01575518 0,03286927 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01575518 0,03284122 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01575518 0,03281323 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01575518 0,03278528 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01575518 0,03275737 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01575518 0,03272952 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01575518 0,03270171 ! cranial nerve development GO:0021545 23 12 0,000 0,01575518 0,03267395 ! fucose catabolic process GO:0019317 25 12 0,000 0,01575518 0,03264624 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01575518 0,03261857 ! histone acetylation GO:0016573 27 12 0,000 0,01575518 0,03259095 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01575518 0,03256338 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01575518 0,03253585 ! zymogen activation GO:0031638 18 12 0,000 0,01575518 0,03250837 ! T cell homeostasis GO:0043029 28 12 0,000 0,01575518 0,03248094 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01575518 0,03245355 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01575518 0,03242621 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,01575518 0,03239892 ! oocyte differentiation GO:0009994 21 12 0,000 0,01575518 0,03237167 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,01575518 0,03234447 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01575518 0,03231731 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01575518 0,0322902 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,01575518 0,03226313 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01575518 0,03223611 ! defense response to fungus GO:0050832 15 12 0,000 0,01575518 0,03220913 ! developmental induction GO:0031128 22 12 0,000 0,01575518 0,0321822 GO:0045168|cell-cell signaling involved in cell fate specification, ! lamellipodium assembly GO:0030032 24 12 0,000 0,01575518 0,03215532 ! response to cold GO:0009409 17 12 0,000 0,01575518 0,03212848 ! establishment of cell polarity GO:0030010 21 12 0,000 0,01575518 0,03210168 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01575518 0,03207493 ! localization within membrane GO:0051668 26 12 0,000 0,01575518 0,03204822 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,0170571 0,03466762 ! cGMP metabolic process GO:0046068 18 13 0,000 0,0170571 0,03463881 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,0170571 0,03461004 ! regulation of chemokine production GO:0032642 18 13 0,000 0,0170571 0,03458131 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,0170571 0,03455264 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,0170571 0,03452401 ! peroxisomal transport GO:0043574 28 13 0,000 0,0170571 0,03449543 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,0170571 0,0344669 ! cartilage condensation GO:0001502 22 13 0,000 0,0170571 0,03443842 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,0170571 0,03440998 ! organelle fusion GO:0048284 36 13 0,000 0,0170571 0,03438159 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,0170571 0,03435324 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,0170571 0,03432495 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,0170571 0,03429669 ! endocrine pancreas development GO:0031018 25 13 0,000 0,0170571 0,03426849 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,0170571 0,03424033 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,0170571 0,03421222 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,0170571 0,03418415 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,0170571 0,03415613 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,0170571 0,03412816 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,0170571 0,03410023 ! methionine metabolic process GO:0006555 31 13 0,000 0,0170571 0,03407235 ! plasma membrane organization GO:0007009 27 13 0,000 0,0170571 0,03404451 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,0170571 0,03401672 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,0170571 0,03398898 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,0170571 0,03396127 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,0170571 0,03393362 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,0170571 0,03390601 ! cytokine metabolic process GO:0042107 24 13 0,000 0,0170571 0,03387844 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,0170571 0,03385092 ! exocrine system development GO:0035272 34 13 0,000 0,0170571 0,03382344 ! asymmetric protein localization GO:0008105 24 13 0,000 0,0170571 0,03379601 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,0170571 0,03376863 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,0170571 0,03374128 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,0170571 0,03371398 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,0170571 0,03368673 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,0170571 0,03365952 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,0170571 0,03363235 ! protein homotetramerization GO:0051289 24 13 0,000 0,0170571 0,03360523 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,0170571 0,03357815 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,0170571 0,03355111 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,0170571 0,03352412 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,0170571 0,03349717 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,0170571 0,03347027 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,0170571 0,03344341 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,0170571 0,03341659 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,0170571 0,03338981 ! histone methylation GO:0016571 29 13 0,000 0,0170571 0,03336308 ! chromatin silencing GO:0006342 29 13 0,000 0,0170571 0,03333639 ! gland morphogenesis GO:0022612 31 13 0,000 0,0170571 0,03330974 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,0170571 0,03328313 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,0170571 0,03325657 ! regulation of epidermis development GO:0045682 19 13 0,000 0,0170571 0,03323005 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,0170571 0,03320357 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,0170571 0,03317714 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,0170571 0,03315074 ! spleen development GO:0048536 24 13 0,000 0,0170571 0,03312439 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,0170571 0,03309808 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,0170571 0,03307181 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,0170571 0,03304559 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,0170571 0,0330194 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,0170571 0,03299326 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,0170571 0,03296715 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,0170571 0,03294109 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,0170571 0,03291507 ! insulin secretion GO:0030073 24 13 0,000 0,0170571 0,0328891 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,0170571 0,03286316 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,0170571 0,03283726 ! acrosome reaction GO:0007340 19 13 0,000 0,0170571 0,0328114 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,0170571 0,03278559 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,0170571 0,03275981 ! rRNA transcription GO:0009303 28 14 0,000 0,01835732 0,03522933 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,01835732 0,03520168 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,01835732 0,03517407 ! water transport GO:0006833 21 14 0,000 0,01835732 0,0351465 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,01835732 0,03511898 ! non-recombinational repair GO:0000726 29 14 0,000 0,01835732 0,0350915 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,01835732 0,03506406 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,01835732 0,03503667 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,01835732 0,03500932 ! RNA polyadenylation GO:0043631 32 14 0,000 0,01835732 0,03498201 ! lipid localization GO:0010876 32 14 0,000 0,01835732 0,03495474 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,01835732 0,03492752 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,01835732 0,03490034 ! regulated secretory pathway GO:0045055 24 14 0,000 0,01835732 0,0348732 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,01835732 0,0348461 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,01835732 0,03481905 ! arginine metabolic process GO:0006525 21 14 0,000 0,01835732 0,03479204 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,01835732 0,03476507 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,01835732 0,03473814 ! regulation of heart rate GO:0002027 25 14 0,000 0,01835732 0,03471125 ! fear response GO:0042596 34 14 0,000 0,01835732 0,0346844 ! organic alcohol transport GO:0015850 29 14 0,000 0,01835732 0,0346576 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,01835732 0,03463084 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,01835732 0,03460412 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01835732 0,03457744 ! neutral amino acid transport GO:0015804 28 14 0,000 0,01835732 0,0345508 ! bone mineralization GO:0030282 18 14 0,000 0,01835732 0,0345242 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,01835732 0,03449764 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,01835732 0,03447113 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,01835732 0,03444465 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,01835732 0,03441822 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,01835732 0,03439182 ! regulation of cellular pH GO:0030641 27 14 0,000 0,01835732 0,03436547 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,01835732 0,03433915 ! ribosome assembly GO:0042255 18 14 0,000 0,01835732 0,03431288 ! cerebellum development GO:0021549 23 14 0,000 0,01835732 0,03428665 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,01835732 0,03426045 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,01835732 0,0342343 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,01835732 0,03420819 ! response to gamma radiation GO:0010332 30 14 0,000 0,01835732 0,03418212 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,01835732 0,03415608 ! NADP metabolic process GO:0006739 24 14 0,000 0,01835732 0,03413009 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,01835732 0,03410413 ! oxygen transport GO:0015671 22 14 0,000 0,01835732 0,03407822 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01835732 0,03405234 ! male genitalia development GO:0030539 26 14 0,000 0,01835732 0,03402651 ! regulation of RNA stability GO:0043487 33 14 0,000 0,01835732 0,03400071 ! regulation of axon extension GO:0030516 43 14 0,000 0,01835732 0,03397495 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,01835732 0,03394923 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,01835732 0,03392355 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,01835732 0,03389791 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01965586 0,03626833 ! lactation GO:0007595 30 15 0,000 0,01965586 0,03624096 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,01965586 0,03621363 ! reproductive cellular process GO:0048610 22 15 0,000 0,01965586 0,03618634 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01965586 0,03615909 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,01965586 0,03613188 ! superoxide anion generation GO:0042554 22 15 0,000 0,01965586 0,03610472 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,01965586 0,03607759 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,01965586 0,03605051 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,01965586 0,03602346 ! copper ion transport GO:0006825 22 15 0,000 0,01965586 0,03599646 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,01965586 0,03596949 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,01965586 0,03594257 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,01965586 0,03591569 ! sulfate transport GO:0008272 27 15 0,000 0,01965586 0,03588884 ! response to cAMP GO:0051591 25 15 0,000 0,01965586 0,03586204 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,01965586 0,03583528 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,01965586 0,03580856 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,01965586 0,03578187 ! response to hexose stimulus GO:0009746 25 15 0,000 0,01965586 0,03575523 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,01965586 0,03572863 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,01965586 0,03570206 ! vesicle coating GO:0006901 38 15 0,000 0,01965586 0,03567554 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,01965586 0,03564905 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,01965586 0,03562261 ! regulation of exocytosis GO:0017157 26 15 0,000 0,01965586 0,0355962 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,01965586 0,03556983 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,01965586 0,0355435 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,01965586 0,03551721 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,01965586 0,03549096 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,01965586 0,03546475 ! regulation of vasodilation GO:0042312 27 15 0,000 0,01965586 0,03543858 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,01965586 0,03541244 ! histone deacetylation GO:0016575 24 15 0,000 0,01965586 0,03538635 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01965586 0,03536029 ! water homeostasis GO:0030104 28 15 0,000 0,01965586 0,03533427 ! cofactor transport GO:0051181 30 15 0,000 0,01965586 0,03530829 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01965586 0,03528235 ! muscle maintenance GO:0046716 26 15 0,000 0,01965586 0,03525644 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,01965586 0,03523057 ! intestinal absorption GO:0050892 31 15 0,000 0,01965586 0,03520475 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01965586 0,03517896 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,01965586 0,0351532 ! heme biosynthetic process GO:0006783 33 15 0,000 0,01965586 0,03512749 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,01965586 0,03510181 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,01965586 0,03507617 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,01965586 0,03505056 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,01965586 0,035025 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,01965586 0,03499947 ! actin filament polymerization GO:0030041 27 15 0,000 0,01965586 0,03497398 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,01965586 0,03494853 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,02095272 0,03722728 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02095272 0,03720022 ! positive regulation of cell size GO:0045793 29 16 0,000 0,02095272 0,03717321 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,02095272 0,03714623 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,02095272 0,03711929 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,02095272 0,0370924 ! bone remodeling GO:0046849 28 16 0,000 0,02095272 0,03706554 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,02095272 0,03703872 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,02095272 0,03701193 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02095272 0,03698519 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,02095272 0,03695849 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,02095272 0,03693182 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,02095272 0,03690519 ! startle response GO:0001964 28 16 0,000 0,02095272 0,03687861 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,02095272 0,03685206 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,02095272 0,03682554 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,02095272 0,03679907 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,02095272 0,03677263 ! protein polyubiquitination GO:0000209 41 16 0,000 0,02095272 0,03674623 ! glutamate metabolic process GO:0006536 25 16 0,000 0,02095272 0,03671987 ! response to osmotic stress GO:0006970 27 16 0,000 0,02095272 0,03669355 ! lysosomal transport GO:0007041 31 16 0,000 0,02095272 0,03666727 ! fructose metabolic process GO:0006000 25 16 0,000 0,02095272 0,03664102 ! L-amino acid transport GO:0015807 33 16 0,000 0,02095272 0,03661481 ! stem cell development GO:0048864 46 16 0,000 0,02095272 0,03658864 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02095272 0,0365625 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02095272 0,03653641 ! intermediate filament-based process GO:0045103 36 16 0,000 0,02095272 0,03651035 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,02095272 0,03648432 ! negative regulation of immune response GO:0050777 38 16 0,000 0,02095272 0,03645834 ! axon cargo transport GO:0008088 46 16 0,000 0,02095272 0,03643239 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,02095272 0,03640648 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,02095272 0,0363806 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,02095272 0,03635476 ! DNA replication initiation GO:0006270 28 16 0,000 0,02095272 0,03632896 ! neuron recognition GO:0008038 40 16 0,000 0,02095272 0,0363032 ! mRNA splice site selection GO:0006376 44 16 0,000 0,02095272 0,03627747 ! tissue regeneration GO:0042246 27 16 0,000 0,02095272 0,03625177 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,02095272 0,03622612 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,02095272 0,0362005 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,02095272 0,03617492 ! biomineral formation GO:0031214 22 16 0,000 0,02095272 0,03614937 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,02095272 0,03612386 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,02095272 0,03609838 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,02095272 0,03607294 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02095272 0,03604754 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,02095272 0,03602217 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,02095272 0,03599684 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,02095272 0,03597154 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,02095272 0,03594628 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02095272 0,03592106 ! peptide hormone processing GO:0016486 27 16 0,000 0,02095272 0,03589587 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,02224791 0,03808804 ! metencephalon development GO:0022037 32 17 0,000 0,02224791 0,03806137 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,02224791 0,03803473 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,02224791 0,03800814 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,02224791 0,03798158 ! signal complex assembly GO:0007172 47 17 0,000 0,02224791 0,03795505 ! filopodium assembly GO:0046847 42 17 0,000 0,02224791 0,03792857 ! endothelial cell migration GO:0043542 31 17 0,000 0,02224791 0,03790212 ! gene silencing by RNA GO:0031047 38 17 0,000 0,02224791 0,0378757 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,02224791 0,03784933 ! glial cell development GO:0021782 28 17 0,000 0,02224791 0,03782299 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,02224791 0,03779669 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,02224791 0,03777042 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,02224791 0,03774419 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,02224791 0,037718 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,02224791 0,03769184 ! myoblast differentiation GO:0045445 50 17 0,000 0,02224791 0,03766572 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,02224791 0,03763964 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,02224791 0,03761359 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,02224791 0,03758758 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,02224791 0,0375616 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,02224791 0,03753566 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,02224791 0,03750975 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,02224791 0,03748389 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,02224791 0,03745805 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,02224791 0,03743226 ! membrane budding GO:0006900 42 17 0,000 0,02224791 0,03740649 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,02224791 0,03738077 ! regulation of protein binding GO:0043393 33 17 0,000 0,02224791 0,03735508 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,02224791 0,03732942 ! genitalia development GO:0048806 32 17 0,000 0,02224791 0,0373038 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,02224791 0,03727821 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,02224791 0,03725266 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,02224791 0,03722715 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,02224791 0,03720167 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,02224791 0,03717622 ! steroid catabolic process GO:0006706 34 17 0,000 0,02224791 0,03715081 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,02224791 0,03712543 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,02224791 0,03710009 ! gas transport GO:0015669 26 17 0,000 0,02224791 0,03707478 ! organic cation transport GO:0015695 32 17 0,000 0,02224791 0,03704951 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,02224791 0,03702427 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,02224791 0,03699907 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,02354141 0,03912358 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,02354141 0,03909699 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,02354141 0,03907043 ! limbic system development GO:0021761 40 18 0,000 0,02354141 0,0390439 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02354141 0,03901741 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,02354141 0,03899096 ! adult walking behavior GO:0007628 36 18 0,000 0,02354141 0,03896454 ! patterning of blood vessels GO:0001569 43 18 0,000 0,02354141 0,03893816 ! heart looping GO:0001947 34 18 0,000 0,02354141 0,03891182 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,02354141 0,03888551 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,02354141 0,03885923 ! centrosome cycle GO:0007098 26 18 0,000 0,02354141 0,038833 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,02354141 0,03880679 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,02354141 0,03878063 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,02354141 0,03875449 ! glycine metabolic process GO:0006544 30 18 0,000 0,02354141 0,0387284 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02354141 0,03870233 ! response to retinoic acid GO:0032526 31 18 0,000 0,02354141 0,03867631 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,02354141 0,03865031 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,02354141 0,03862436 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,02354141 0,03859843 ! DNA integration GO:0015074 32 18 0,000 0,02354141 0,03857255 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,02354141 0,03854669 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,02354141 0,03852088 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,02354141 0,03849509 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,02354141 0,03846934 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,02354141 0,03844363 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,02354141 0,03841795 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,02354141 0,0383923 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,02354141 0,03836669 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,02354141 0,03834111 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,02354141 0,03831557 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,02354141 0,03829006 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,02354141 0,03826458 ! detection of bacterium GO:0016045 22 18 0,000 0,02354141 0,03823914 ! nerve development GO:0021675 34 18 0,000 0,02354141 0,03821373 ! defense response to virus GO:0051607 43 18 0,000 0,02354141 0,03818836 ! microspike assembly GO:0030035 46 18 0,000 0,02354141 0,03816302 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,02354141 0,03813771 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,02354141 0,03811244 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,02483324 0,04017722 ! positive regulation of translation GO:0045727 31 19 0,000 0,02483324 0,04015063 ! negative regulation of defense response GO:0031348 27 19 0,000 0,02483324 0,04012408 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,02483324 0,04009756 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,02483324 0,04007108 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,02483324 0,04004463 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,02483324 0,04001821 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,02483324 0,03999183 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,02483324 0,03996549 ! inositol metabolic process GO:0006020 33 19 0,000 0,02483324 0,03993918 ! memory GO:0007613 34 19 0,000 0,02483324 0,0399129 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,02483324 0,03988666 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,02483324 0,03986045 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,02483324 0,03983428 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,02483324 0,03980814 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,02483324 0,03978204 ! cerebral cortex development GO:0021987 40 19 0,000 0,02483324 0,03975597 ! pigmentation during development GO:0048066 42 19 0,000 0,02483324 0,03972993 ! response to vitamin A GO:0033189 32 19 0,000 0,02483324 0,03970393 ! heme metabolic process GO:0042168 40 19 0,000 0,02483324 0,03967796 ! neuromuscular junction development GO:0007528 43 19 0,000 0,02483324 0,03965203 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,02483324 0,03962613 ! response to fungus GO:0009620 26 19 0,000 0,02483324 0,03960027 ! protein export from nucleus GO:0006611 40 19 0,000 0,02483324 0,03957443 ! heart process GO:0003015 32 19 0,000 0,02483324 0,03954864 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,02483324 0,03952287 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,02483324 0,03949714 ! visual learning GO:0008542 38 19 0,000 0,02483324 0,03947144 ! cellular pigmentation GO:0033059 37 19 0,000 0,02483324 0,03944578 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,02483324 0,03942015 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,02483324 0,03939455 ! vitamin transport GO:0051180 31 19 0,000 0,02483324 0,03936899 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,02483324 0,03934346 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,02483324 0,03931796 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,02483324 0,03929249 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,02483324 0,03926706 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,02483324 0,03924166 ! cilium assembly GO:0042384 38 19 0,000 0,02483324 0,03921629 ! peptide hormone secretion GO:0030072 32 19 0,000 0,02483324 0,03919096 ! protein secretion GO:0009306 45 20 0,000 0,0261234 0,04120043 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,0261234 0,04117385 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,0261234 0,0411473 ! positive regulation of ossification GO:0045778 50 20 0,000 0,0261234 0,04112079 ! skin development GO:0043588 42 20 0,000 0,0261234 0,04109431 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,0261234 0,04106786 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,0261234 0,04104145 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,0261234 0,04101508 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,0261234 0,04098874 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,0261234 0,04096243 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,0261234 0,04093615 ! response to vitamin GO:0033273 36 20 0,000 0,0261234 0,04090991 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,0261234 0,0408837 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,0261234 0,04085753 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,0261234 0,04083139 ! bile acid metabolic process GO:0008206 34 20 0,000 0,0261234 0,04080528 ! response to alkaloid GO:0043279 38 20 0,000 0,0261234 0,04077921 ! retinoid metabolic process GO:0001523 34 20 0,000 0,0261234 0,04075317 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,0261234 0,04072716 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,0261234 0,04070119 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,0261234 0,04067525 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,0261234 0,04064934 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,0261234 0,04062346 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,0261234 0,04059762 ! actin filament bundle formation GO:0051017 47 20 0,000 0,0261234 0,04057181 ! body fluid secretion GO:0007589 33 20 0,000 0,0261234 0,04054604 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,0261234 0,04052029 ! peptide secretion GO:0002790 38 20 0,000 0,0261234 0,04049458 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,0261234 0,0404689 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,0261234 0,04044326 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,0261234 0,04041765 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,0261234 0,04039206 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,0261234 0,04036652 ! cell-cell junction organization GO:0045216 43 20 0,000 0,0261234 0,040341 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,0261234 0,04031552 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,0261234 0,04029006 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,0261234 0,04026464 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,0261234 0,04023926 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,0261234 0,0402139 ! regulation of glucose import GO:0046324 30 20 0,000 0,0261234 0,04018858 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,0261234 0,04016329 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,0261234 0,04013803 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,0261234 0,0401128 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,0261234 0,0400876 ! regulation of cell killing GO:0031341 46 21 0,000 0,02741188 0,04203844 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,02741188 0,04201207 ! hormone secretion GO:0046879 39 21 0,000 0,02741188 0,04198573 ! lipid phosphorylation GO:0046834 43 21 0,000 0,02741188 0,04195942 ! cAMP metabolic process GO:0046058 41 21 0,000 0,02741188 0,04193315 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,02741188 0,04190691 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,02741188 0,0418807 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,02741188 0,04185452 ! ovarian follicle development GO:0001541 39 21 0,000 0,02741188 0,04182838 ! smooth muscle contraction GO:0006939 48 21 0,000 0,02741188 0,04180227 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,02741188 0,04177619 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,02741188 0,04175015 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,02741188 0,04172413 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,02741188 0,04169815 ! plasma membrane fusion GO:0045026 33 21 0,000 0,02741188 0,04167221 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,02741188 0,04164629 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,02741188 0,04162041 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,02741188 0,04159456 ! sensory perception of pain GO:0019233 33 21 0,000 0,02741188 0,04156874 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,02741188 0,04154295 ! collagen fibril organization GO:0030199 62 21 0,000 0,02741188 0,04151719 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,02741188 0,04149147 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,02741188 0,04146578 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,02741188 0,04144012 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,02741188 0,04141449 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,02741188 0,0413889 ! collagen catabolic process GO:0030574 29 21 0,000 0,02741188 0,04136333 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,02741188 0,0413378 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,02741188 0,0413123 ! sperm-egg recognition GO:0035036 23 21 0,000 0,02741188 0,04128683 ! actin filament-based movement GO:0030048 47 21 0,000 0,02741188 0,04126139 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,02741188 0,04123598 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,0286987 0,04314519 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,0286987 0,04311865 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,0286987 0,04309215 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,0286987 0,04306568 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,0286987 0,04303925 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,0286987 0,04301284 ! microtubule-based transport GO:0010970 59 22 0,000 0,0286987 0,04298647 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,0286987 0,04296013 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,0286987 0,04293382 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,0286987 0,04290755 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,0286987 0,0428813 ! vacuolar transport GO:0007034 41 22 0,000 0,0286987 0,04285509 ! central nervous system neuron development GO:0021954 47 22 0,000 0,0286987 0,04282891 ! fucose metabolic process GO:0006004 44 22 0,000 0,0286987 0,04280277 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,0286987 0,04277665 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,0286987 0,04275057 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,0286987 0,04272452 ! cell aging GO:0007569 48 22 0,000 0,0286987 0,0426985 ! stem cell differentiation GO:0048863 57 22 0,000 0,0286987 0,04267251 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,0286987 0,04264655 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,0286987 0,04262063 ! cytolysis GO:0019835 27 22 0,000 0,0286987 0,04259473 ! renal system process GO:0003014 42 22 0,000 0,0286987 0,04256887 ! vasodilation GO:0042311 40 22 0,000 0,0286987 0,04254304 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,0286987 0,04251724 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,0286987 0,04249147 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,0286987 0,04246574 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,0286987 0,04244003 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,0286987 0,04241436 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,0286987 0,04238871 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,0286987 0,0423631 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,0286987 0,04233752 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,0286987 0,04231197 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,0286987 0,04228645 ! sarcomere organization GO:0045214 32 22 0,000 0,0286987 0,04226096 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,0286987 0,0422355 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,0286987 0,04221007 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,0286987 0,04218468 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,0286987 0,04215931 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,0286987 0,04213397 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,0286987 0,04210867 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,0286987 0,04208339 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,0286987 0,04205815 ! protein stabilization GO:0050821 41 22 0,000 0,0286987 0,04203293 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,02998385 0,04388889 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,02998385 0,04386261 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,02998385 0,04383636 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,02998385 0,04381014 ! gluconeogenesis GO:0006094 38 23 0,000 0,02998385 0,04378396 ! glycerol metabolic process GO:0006071 40 23 0,000 0,02998385 0,0437578 ! viral genome replication GO:0019079 44 23 0,000 0,02998385 0,04373168 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,02998385 0,04370558 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,02998385 0,04367952 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,02998385 0,04365349 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,02998385 0,04362749 ! regeneration GO:0031099 42 23 0,000 0,02998385 0,04360152 ! axis specification GO:0009798 43 23 0,000 0,02998385 0,04357558 ! visual behavior GO:0007632 46 23 0,000 0,02998385 0,04354968 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,02998385 0,0435238 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,02998385 0,04349796 ! response to ethanol GO:0045471 47 23 0,000 0,02998385 0,04347214 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,02998385 0,04344636 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,02998385 0,0434206 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,02998385 0,04339488 ! peroxisome organization GO:0007031 43 23 0,000 0,02998385 0,04336919 ! lysosome organization GO:0007040 47 23 0,000 0,02998385 0,04334353 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,02998385 0,04331789 ! vesicle targeting GO:0006903 49 23 0,000 0,02998385 0,04329229 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,02998385 0,04326672 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,02998385 0,04324118 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,02998385 0,04321567 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,02998385 0,04319019 ! DNA modification GO:0006304 36 23 0,000 0,02998385 0,04316474 ! fatty acid transport GO:0015908 47 23 0,000 0,02998385 0,04313932 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,02998385 0,04311392 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,02998385 0,04308856 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,02998385 0,04306323 ! hormone transport GO:0009914 41 23 0,000 0,02998385 0,04303793 ! cell-cell recognition GO:0009988 28 23 0,000 0,02998385 0,04301266 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,02998385 0,04298742 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,02998385 0,0429622 GO:0006099|tricarboxylic acid cycle, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,03126734 0,04477498 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,03126734 0,04474875 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,03126734 0,04472255 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,03126734 0,04469638 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,03126734 0,04467024 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,03126734 0,04464414 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,03126734 0,04461806 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,03126734 0,04459201 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,03126734 0,044566 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,03126734 0,04454001 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,03126734 0,04451405 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,03126734 0,04448813 ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,03126734 0,04446223 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,03126734 0,04443637 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,03126734 0,04441053 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,03126734 0,04438473 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,03126734 0,04435895 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,03126734 0,04433321 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,03126734 0,04430749 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,03126734 0,04428181 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,03126734 0,04425615 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,03126734 0,04423053 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,03126734 0,04420493 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,03126734 0,04417936 ! membrane depolarization GO:0051899 45 24 0,000 0,03126734 0,04415383 ! pallium development GO:0021543 56 24 0,000 0,03126734 0,04412832 ! oogenesis GO:0048477 44 24 0,000 0,03126734 0,04410284 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,03126734 0,04407739 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,03126734 0,04405197 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,03126734 0,04402658 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,03126734 0,04400122 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,03126734 0,04397589 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,03126734 0,04395059 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,03126734 0,04392531 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,03126734 0,04390007 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,03126734 0,04387485 ! regulation of amine transport GO:0051952 41 24 0,000 0,03126734 0,04384967 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,03126734 0,04382451 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,03254917 0,04559496 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,03254917 0,04556883 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,03254917 0,04554274 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,03254917 0,04551667 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,03254917 0,04549063 ! leukocyte adhesion GO:0007159 55 25 0,000 0,03254917 0,04546462 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,03254917 0,04543864 ! phototransduction GO:0007602 37 25 0,000 0,03254917 0,04541269 ! keratinization GO:0031424 37 25 0,000 0,03254917 0,04538677 ! vasculogenesis GO:0001570 49 25 0,000 0,03254917 0,04536088 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,03254917 0,04533502 ! vacuole organization GO:0007033 49 25 0,000 0,03254917 0,04530918 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,03254917 0,04528338 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,03254917 0,04525761 ! receptor metabolic process GO:0043112 53 25 0,000 0,03254917 0,04523186 ! chromosome condensation GO:0030261 48 25 0,000 0,03254917 0,04520615 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,03254917 0,04518046 ! regulation of behavior GO:0050795 48 25 0,000 0,03254917 0,04515481 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,03254917 0,04512918 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,03254917 0,04510358 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,03254917 0,04507801 ! immunoglobulin production GO:0002377 62 25 0,000 0,03254917 0,04505247 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,03254917 0,04502696 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,03254917 0,04500148 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,03254917 0,04497603 ! protein tetramerization GO:0051262 57 25 0,000 0,03254917 0,0449506 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,03382933 0,04669212 ! myelination GO:0042552 50 26 0,000 0,03382933 0,04666576 ! initiation of viral infection GO:0019059 60 26 0,000 0,03382933 0,04663942 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,03382933 0,04661312 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,03382933 0,04658684 ! molting cycle process GO:0022404 52 26 0,000 0,03382933 0,0465606 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,03382933 0,04653438 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,03382933 0,04650819 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,03382933 0,04648204 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,03382933 0,04645591 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,03382933 0,04642981 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,03382933 0,04640374 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,03382933 0,0463777 ! digestive system process GO:0022600 49 26 0,000 0,03382933 0,04635169 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,03382933 0,04632571 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,03382933 0,04629975 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,03382933 0,04627383 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,03382933 0,04624794 ! osteoblast differentiation GO:0001649 63 26 0,000 0,03382933 0,04622207 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,03382933 0,04619623 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,03382933 0,04617042 ! negative regulation of cell development GO:0010721 83 26 0,000 0,03382933 0,04614465 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,03382933 0,0461189 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,03382933 0,04609317 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,03382933 0,04606748 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,03382933 0,04604182 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,03382933 0,04601618 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,03382933 0,04599057 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,03382933 0,04596499 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,03382933 0,04593944 ! blastocyst development GO:0001824 50 26 0,000 0,03382933 0,04591392 ! telomere organization GO:0032200 46 26 0,000 0,03382933 0,04588843 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,03382933 0,04586296 ! neural tube closure GO:0001843 58 26 0,000 0,03382933 0,04583753 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,03382933 0,04581212 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,03382933 0,04578674 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,03382933 0,04576138 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,03510784 0,04746456 ! embryonic pattern specification GO:0009880 49 27 0,000 0,03510784 0,0474383 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,03510784 0,04741208 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,03510784 0,04738589 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,03510784 0,04735972 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,03510784 0,04733358 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,03510784 0,04730748 ! iron ion transport GO:0006826 65 27 0,000 0,03510784 0,0472814 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,03510784 0,04725535 ! superoxide metabolic process GO:0006801 41 27 0,000 0,03510784 0,04722932 ! tube lumen formation GO:0035148 59 27 0,000 0,03510784 0,04720333 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,03510784 0,04717737 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,03510784 0,04715143 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,03510784 0,04712552 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,03510784 0,04709964 ! response to toxin GO:0009636 49 27 0,000 0,03510784 0,04707379 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,03510784 0,04704797 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,03510784 0,04702218 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,03510784 0,04699641 ! leukocyte proliferation GO:0070661 59 27 0,000 0,03510784 0,04697068 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,03510784 0,04694497 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,03638469 0,04862571 ! neuron fate commitment GO:0048663 52 28 0,000 0,03638469 0,04859913 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,03638469 0,04857257 ! protein amino acid acylation GO:0043543 59 28 0,000 0,03638469 0,04854604 ! vesicle docking GO:0048278 55 28 0,000 0,03638469 0,04851954 ! circadian rhythm GO:0007623 56 28 0,000 0,03638469 0,04849307 ! dendrite development GO:0016358 67 28 0,000 0,03638469 0,04846663 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,03638469 0,04844022 ! fat cell differentiation GO:0045444 57 28 0,000 0,03638469 0,04841384 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,03638469 0,04838748 ! sperm motility GO:0030317 37 28 0,000 0,03638469 0,04836115 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,03638469 0,04833486 ! base-excision repair GO:0006284 41 28 0,000 0,03638469 0,04830859 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,03638469 0,04828235 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,03638469 0,04825614 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,03638469 0,04822995 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,03638469 0,0482038 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,03638469 0,04817767 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,03638469 0,04815157 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,03638469 0,0481255 ! glutathione metabolic process GO:0006749 42 28 0,000 0,03638469 0,04809946 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,03638469 0,04807345 ! lipid oxidation GO:0034440 48 28 0,000 0,03638469 0,04804746 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,03638469 0,0480215 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,03638469 0,04799557 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,03765989 0,0496509 ! translational initiation GO:0006413 66 29 0,000 0,03765989 0,04962412 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,03765989 0,04959736 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,03765989 0,04957064 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,03765989 0,04954395 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,03765989 0,04951728 ! autophagy GO:0006914 47 29 0,000 0,03765989 0,04949065 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,03765989 0,04946404 ! primary neural tube formation GO:0014020 61 29 0,000 0,03765989 0,04943746 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,03765989 0,04941091 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,03765989 0,04938439 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,03765989 0,04935789 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,03765989 0,04933143 ! somitogenesis GO:0001756 52 29 0,000 0,03765989 0,04930499 ! synaptogenesis GO:0007416 46 29 0,000 0,03765989 0,04927858 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,03765989 0,0492522 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,03765989 0,04922585 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,03765989 0,04919952 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,03765989 0,04917323 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,03893344 0,05080896 ! phenol metabolic process GO:0018958 56 30 0,000 0,03893344 0,05078184 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,03893344 0,05075474 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,03893344 0,05072767 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,03893344 0,05070063 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,03893344 0,05067362 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,03893344 0,05064664 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,03893344 0,05061968 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,03893344 0,05059276 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,03893344 0,05056586 ! myofibril assembly GO:0030239 50 30 0,000 0,03893344 0,05053899 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,03893344 0,05051215 ! determination of left/right symmetry GO:0007368 53 30 0,000 0,03893344 0,05048534 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,03893344 0,05045856 ! phospholipid transport GO:0015914 65 30 0,000 0,03893344 0,0504318 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,03893344 0,05040508 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,03893344 0,05037838 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,03893344 0,05035171 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,03893344 0,05032507 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,03893344 0,05029846 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,03893344 0,05027187 ! regulation of coagulation GO:0050818 52 30 0,000 0,03893344 0,05024532 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,04020533 0,05185936 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,04020533 0,05183199 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,04020533 0,05180465 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,04020533 0,05177735 ! cell junction assembly GO:0034329 85 31 0,000 0,04020533 0,05175007 ! regulation of innate immune response GO:0045088 57 31 0,000 0,04020533 0,05172281 ! ovulation cycle process GO:0022602 55 31 0,000 0,04020533 0,05169559 ! peptide transport GO:0015833 60 31 0,000 0,04020533 0,0516684 ! male gonad development GO:0008584 56 31 0,000 0,04020533 0,05164123 ! iron ion homeostasis GO:0055072 60 31 0,000 0,04020533 0,0516141 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,04020533 0,05158699 ! detection of light stimulus GO:0009583 44 31 0,000 0,04020533 0,05155991 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,04020533 0,05153286 ! natural killer cell activation GO:0030101 50 31 0,000 0,04020533 0,05150583 ! ensheathment of neurons GO:0007272 64 31 0,000 0,04020533 0,05147884 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,04020533 0,05145187 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,04020533 0,05142493 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,04020533 0,05139802 ! eye morphogenesis GO:0048592 65 31 0,000 0,04020533 0,05137114 ! response to heat GO:0009408 54 31 0,000 0,04020533 0,05134429 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,04020533 0,05131746 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,04147558 0,05291115 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,04147558 0,05288353 ! collagen metabolic process GO:0032963 49 32 0,000 0,04147558 0,05285594 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,04147558 0,05282839 ! spindle organization GO:0007051 50 32 0,000 0,04147558 0,05280086 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,04147558 0,05277336 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,04147558 0,05274588 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,04147558 0,05271844 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,04147558 0,05269103 ! muscle cell development GO:0055001 52 32 0,000 0,04147558 0,05266364 ! mesoderm formation GO:0001707 73 32 0,000 0,04147558 0,05263628 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,04147558 0,05260895 ! ovulation cycle GO:0042698 57 32 0,000 0,04147558 0,05258165 ! peripheral nervous system development GO:0007422 68 32 0,000 0,04147558 0,05255438 ! BMP signaling pathway GO:0030509 71 32 0,000 0,04147558 0,05252713 ! hindbrain development GO:0030902 65 32 0,000 0,04147558 0,05249992 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,04147558 0,05247273 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,04147558 0,05244557 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,04147558 0,05241844 ! gene silencing GO:0016458 71 32 0,000 0,04147558 0,05239134 ! regulation of pH GO:0006885 56 33 0,000 0,04274418 0,05396591 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,04274418 0,05393804 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,04274418 0,05391019 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,04274418 0,05388237 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,04274418 0,05385459 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,04274418 0,05382683 ! response to ionizing radiation GO:0010212 74 33 0,000 0,04274418 0,05379909 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,04274418 0,05377139 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,04274418 0,05374372 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,04274418 0,05371607 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,04274418 0,05368845 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,04274418 0,05366086 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,04274418 0,0536333 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,04274418 0,05360577 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,04401114 0,05516635 ! glial cell differentiation GO:0010001 67 34 0,000 0,04401114 0,05513806 ! post-embryonic development GO:0009791 76 34 0,000 0,04401114 0,0551098 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,04401114 0,05508157 ! cholesterol transport GO:0030301 62 34 0,000 0,04401114 0,05505337 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,04401114 0,05502519 ! spliceosome assembly GO:0000245 75 34 0,000 0,04401114 0,05499705 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,04401114 0,05496893 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,04401114 0,05494084 ! formation of primary germ layer GO:0001704 76 34 0,000 0,04401114 0,05491278 ! cell fate specification GO:0001708 56 34 0,000 0,04401114 0,05488475 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,04401114 0,05485675 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,04401114 0,05482877 ! adult locomotory behavior GO:0008344 62 34 0,000 0,04401114 0,05480083 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,04527646 0,05634763 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,04527646 0,05631894 ! negative regulation of secretion GO:0051048 68 35 0,000 0,04527646 0,05629028 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,04527646 0,05626165 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,04527646 0,05623304 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,04527646 0,05620447 ! membrane docking GO:0022406 69 35 0,000 0,04527646 0,05617593 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,04527646 0,05614741 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,04527646 0,05611892 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,04527646 0,05609047 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,04527646 0,05606204 ! ceramide metabolic process GO:0006672 72 35 0,000 0,04527646 0,05603364 ! telencephalon development GO:0021537 81 35 0,000 0,04527646 0,05600527 ! sterol transport GO:0015918 63 35 0,000 0,04527646 0,05597692 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,04527646 0,05594861 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,04527646 0,05592032 ! vesicle localization GO:0051648 70 35 0,000 0,04527646 0,05589207 ! regulation of muscle development GO:0048634 82 36 0,000 0,04654014 0,05742301 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,04654014 0,05739403 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,04654014 0,05736507 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,04654014 0,05733614 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,04654014 0,05730724 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,04654014 0,05727837 ! positive regulation of cell development GO:0010720 85 36 0,000 0,04654014 0,05724953 ! protein targeting to membrane GO:0006612 75 36 0,000 0,04654014 0,05722072 ! regulation of proteolysis GO:0030162 77 36 0,000 0,04654014 0,05719194 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,04654014 0,05716318 ! aerobic respiration GO:0009060 56 36 0,000 0,04654014 0,05713446 ! cytokine production GO:0001816 68 36 0,000 0,04654014 0,05710576 ! embryonic organ development GO:0048568 67 36 0,000 0,04654014 0,05707709 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,04654014 0,05704845 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,04654014 0,05701984 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,04780219 0,05853671 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,04780219 0,05850738 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,04780219 0,05847809 ! sister chromatid segregation GO:0000819 65 37 0,000 0,04780219 0,05844882 ! odontogenesis GO:0042476 74 37 0,000 0,04780219 0,05841958 ! actomyosin structure organization GO:0031032 68 37 0,000 0,04780219 0,05839037 ! cell junction organization GO:0034330 96 37 0,000 0,04780219 0,05836119 ! tissue remodeling GO:0048771 78 37 0,000 0,04780219 0,05833204 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,04780219 0,05830292 ! female gonad development GO:0008585 71 37 0,000 0,04780219 0,05827382 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,04780219 0,05824476 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,04780219 0,05821572 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,04780219 0,05818672 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,04780219 0,05815774 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,04906259 0,05966148 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,04906259 0,0596318 ! meiosis I GO:0007127 74 38 0,000 0,04906259 0,05960215 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,04906259 0,05957252 ! organic anion transport GO:0015711 82 38 0,000 0,04906259 0,05954293 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,04906259 0,05951336 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,04906259 0,05948383 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,04906259 0,05945432 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,04906259 0,05942485 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,04906259 0,0593954 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,04906259 0,05936598 ! regulation of protein stability GO:0031647 77 38 0,000 0,04906259 0,05933659 ! spermatid development GO:0007286 69 38 0,000 0,04906259 0,05930723 ! glycogen metabolic process GO:0005977 63 38 0,000 0,04906259 0,0592779 ! pigment metabolic process GO:0042440 87 38 0,000 0,04906259 0,0592486 ! neural tube formation GO:0001841 79 38 0,000 0,04906259 0,05921933 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,05032137 0,06070869 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,05032137 0,06067873 ! negative regulation of binding GO:0051100 71 39 0,000 0,05032137 0,06064879 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,05032137 0,06061889 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,05032137 0,06058901 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,05032137 0,06055916 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,05032137 0,06052935 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,05032137 0,06049956 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,05032137 0,0604698 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,05032137 0,06044007 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,05032137 0,06041037 ! glucan metabolic process GO:0044042 64 39 0,000 0,05032137 0,0603807 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,05157851 0,06185877 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,05157851 0,06182841 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,05157851 0,06179809 ! learning GO:0007612 82 40 0,000 0,05157851 0,0617678 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,05157851 0,06173753 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,05157851 0,0617073 ! lipid homeostasis GO:0055088 75 40 0,000 0,05157851 0,0616771 ! mismatch repair GO:0006298 58 40 0,000 0,05157851 0,06164692 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,05157851 0,06161678 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,05157851 0,06158666 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,05157851 0,06155657 ! RNA export from nucleus GO:0006405 61 41 0,000 0,05283403 0,06302418 ! mRNA catabolic process GO:0006402 79 41 0,000 0,05283403 0,06299343 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,05283403 0,0629627 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,05283403 0,062932 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,05283403 0,06290133 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,05283403 0,06287069 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,05283403 0,06284008 ! gliogenesis GO:0042063 91 41 0,000 0,05283403 0,0628095 ! feeding behavior GO:0007631 69 41 0,000 0,05283403 0,06277895 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,05283403 0,06274843 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,05283403 0,06271794 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,05283403 0,06268748 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,05283403 0,06265705 ! spermatid differentiation GO:0048515 73 41 0,000 0,05283403 0,06262665 ! RNA modification GO:0009451 64 41 0,000 0,05283403 0,06259628 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,05408792 0,06405079 ! ear morphogenesis GO:0042471 64 42 0,000 0,05408792 0,06401976 ! organic ether metabolic process GO:0018904 59 42 0,000 0,05408792 0,06398875 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,05408792 0,06395778 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,05408792 0,06392684 ! T cell differentiation GO:0030217 93 42 0,000 0,05408792 0,06389593 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,05408792 0,06386504 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,05408792 0,06383419 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,05408792 0,06380337 ! regulation of protein secretion GO:0050708 77 42 0,000 0,05408792 0,06377258 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,05408792 0,06374181 ! cytokinesis GO:0000910 84 42 0,000 0,05408792 0,06371108 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,05408792 0,06368037 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,05534018 0,06512334 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,05534018 0,06509199 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,05534018 0,06506066 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,05534018 0,06502937 ! regulation of tube size GO:0035150 76 43 0,000 0,05534018 0,06499811 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,05534018 0,06496687 ! glucose transport GO:0015758 66 43 0,000 0,05534018 0,06493567 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,05534018 0,06490449 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,05534018 0,06487335 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,05534018 0,06484223 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,05534018 0,06481115 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,05534018 0,0647801 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,05534018 0,06474907 ! segmentation GO:0035282 78 43 0,000 0,05534018 0,06471807 ! ion transmembrane transport GO:0034220 79 43 0,000 0,05534018 0,06468711 ! neuron migration GO:0001764 85 43 0,000 0,05534018 0,06465617 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,05534018 0,06462527 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,05659082 0,06605417 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,05659082 0,06602262 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,05659082 0,06599111 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,05659082 0,06595963 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,05659082 0,06592817 ! hexose transport GO:0008645 68 44 0,000 0,05659082 0,06589675 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,05659082 0,06586535 ! striated muscle contraction GO:0006941 85 44 0,000 0,05659082 0,06583399 ! phagocytosis GO:0006909 105 44 0,000 0,05659082 0,06580265 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,05659082 0,06577135 ! double-strand break repair GO:0006302 85 44 0,000 0,05659082 0,06574007 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,05783984 0,06715909 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,05783984 0,06712719 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,05783984 0,06709531 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,05783984 0,06706347 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,05783984 0,06703166 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,05783984 0,06699987 ! biopolymer methylation GO:0043414 91 45 0,000 0,05783984 0,06696812 ! B cell differentiation GO:0030183 124 45 0,000 0,05783984 0,0669364 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,05783984 0,0669047 ! female gamete generation GO:0007292 71 45 0,000 0,05783984 0,06687304 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,05783984 0,06684141 ! polyol metabolic process GO:0019751 77 45 0,000 0,05783984 0,0668098 ! developmental growth GO:0048589 88 45 0,000 0,05783984 0,06677823 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,05908724 0,06818618 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,05908724 0,06815398 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 0,000 0,05908724 0,06812182 ! glycolysis GO:0006096 71 46 0,000 0,05908724 0,06808969 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,05908724 0,06805758 ! leukocyte migration GO:0050900 75 46 0,000 0,05908724 0,06802551 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,05908724 0,06799347 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,05908724 0,06796146 ! pigmentation GO:0043473 103 46 0,000 0,05908724 0,06792948 ! cell growth GO:0016049 90 46 0,000 0,05908724 0,06789752 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,05908724 0,0678656 ! neural tube development GO:0021915 91 47 0,000 0,06033303 0,06926391 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,06033303 0,06923137 ! positive regulation of defense response GO:0031349 88 48 0,000 0,0615772 0,07062587 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,0615772 0,07059273 ! mitochondrial transport GO:0006839 94 48 0,000 0,0615772 0,07055962 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,0615772 0,07052654 ! cellular component disassembly GO:0022411 89 48 0,000 0,0615772 0,07049349 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,0615772 0,07046047 ! endosome transport GO:0016197 127 48 0,000 0,0615772 0,07042748 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,0615772 0,07039453 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,0615772 0,0703616 ! male sex differentiation GO:0046661 93 48 0,000 0,0615772 0,07032871 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,0615772 0,07029584 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,0615772 0,07026301 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,0615772 0,07023021 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,0615772 0,07019743 ! methylation GO:0032259 97 48 0,000 0,0615772 0,07016469 ! response to calcium ion GO:0051592 94 49 0,000 0,06281976 0,07154717 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,06281976 0,07151383 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,06281976 0,07148052 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,06281976 0,07144724 ! JNK cascade GO:0007254 106 49 0,000 0,06281976 0,07141399 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,06281976 0,07138078 ! regulation of action potential GO:0001508 102 50 0,000 0,06406071 0,072757 ! regulation of ion transport GO:0043269 86 50 0,000 0,06406071 0,07272319 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,06406071 0,07268941 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,06406071 0,07265567 ! activation of caspase activity GO:0006919 95 50 0,000 0,06406071 0,07262195 ! regulation of ossification GO:0030278 123 50 0,000 0,06406071 0,07258827 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,06406071 0,07255462 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,06406071 0,072521 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,06406071 0,07248741 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,06406071 0,07245385 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,06406071 0,07242032 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,06530005 0,07378724 ! viral infectious cycle GO:0019058 104 51 0,000 0,06530005 0,07375313 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,06530005 0,07371905 ! peptide metabolic process GO:0006518 80 51 0,000 0,06530005 0,073685 ! response to temperature stimulus GO:0009266 84 51 0,000 0,06530005 0,07365098 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,06530005 0,07361699 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,06530005 0,07358303 ! positive regulation of binding GO:0051099 88 52 0,000 0,06653778 0,0749432 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,06653778 0,07490866 ! Notch signaling pathway GO:0007219 111 52 0,000 0,06653778 0,07487416 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,06653778 0,07483969 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,06653778 0,07480525 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,06653778 0,07477084 ! excretion GO:0007588 87 52 0,000 0,06653778 0,07473646 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,06653778 0,07470211 ! histone modification GO:0016570 104 52 0,000 0,06653778 0,0746678 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,06653778 0,07463352 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,06653778 0,07459927 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,06653778 0,07456505 ! amino acid activation GO:0043038 98 52 0,000 0,06653778 0,07453086 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,06777391 0,07588069 ! positive regulation of growth GO:0045927 96 53 0,000 0,06777391 0,07584593 ! inner ear development GO:0048839 89 53 0,000 0,06777391 0,0758112 ! chromatin remodeling GO:0006338 122 53 0,000 0,06777391 0,07577651 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,06777391 0,07574184 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,06777391 0,07570721 ! vesicle organization GO:0016050 127 53 0,000 0,06777391 0,07567261 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,06777391 0,07563804 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,06777391 0,0756035 ! cartilage development GO:0051216 99 53 0,000 0,06777391 0,07556899 ! synapse organization GO:0050808 102 53 0,000 0,06777391 0,07553452 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,06900844 0,07687534 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,06900844 0,0768403 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,06900844 0,07680529 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,06900844 0,07677032 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,06900844 0,07673538 ! membrane fusion GO:0006944 122 54 0,000 0,06900844 0,07670046 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,06900844 0,07666558 ! covalent chromatin modification GO:0016569 115 54 0,000 0,06900844 0,07663074 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,06900844 0,07659592 ! RNA catabolic process GO:0006401 103 55 0,000 0,07024137 0,077929 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,07024137 0,07789363 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,07024137 0,07785829 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,07024137 0,07782298 ! cell recognition GO:0008037 98 55 0,000 0,07024137 0,0777877 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,07024137 0,07775245 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,07024137 0,07771724 ! response to UV GO:0009411 120 55 0,000 0,07024137 0,07768206 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,0714727 0,07900805 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,0714727 0,07897232 ! glucose catabolic process GO:0006007 88 56 0,000 0,0714727 0,07893662 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,0714727 0,07890095 ! regulation of DNA replication GO:0006275 105 56 0,000 0,0714727 0,07886531 ! RNA elongation GO:0006354 90 56 0,000 0,0714727 0,07882971 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 0,000 0,07270243 0,08014984 ! chloride transport GO:0006821 102 57 0,000 0,07270243 0,08011368 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,07270243 0,08007756 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,07270243 0,08004148 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,07270243 0,08000542 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,07270243 0,0799694 ! heart morphogenesis GO:0003007 105 57 0,000 0,07270243 0,07993341 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,07270243 0,07989745 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,07270243 0,07986153 ! regulation of actin filament length GO:0030832 118 58 0,000 0,07393057 0,0811741 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,07393057 0,08113764 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,07393057 0,0811012 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,07393057 0,0810648 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,07393057 0,08102844 ! aging GO:0007568 112 58 0,000 0,07393057 0,0809921 ! gastrulation GO:0007369 122 58 0,000 0,07393057 0,0809558 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,07393057 0,08091953 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,07393057 0,08088329 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,07393057 0,08084708 ! nuclear export GO:0051168 110 59 0,000 0,07515712 0,08215161 ! establishment of organelle localization GO:0051656 122 59 0,000 0,07515712 0,08211487 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,07638208 0,08341592 ! lipid modification GO:0030258 112 60 0,000 0,07638208 0,08337865 ! DNA catabolic process GO:0006308 94 60 0,000 0,07638208 0,08334141 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,07638208 0,0833042 ! adult behavior GO:0030534 104 60 0,000 0,07638208 0,08326703 ! positive regulation of secretion GO:0051047 110 61 0,000 0,07760544 0,08456294 ! regulation of cellular component size GO:0032535 125 61 0,000 0,07760544 0,08452523 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,07760544 0,08448757 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,07760544 0,08444993 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,07760544 0,08441233 ! regulation of heart contraction GO:0008016 123 61 0,000 0,07760544 0,08437477 ! camera-type eye development GO:0043010 126 61 0,000 0,07760544 0,08433723 ! proton transport GO:0015992 117 61 0,000 0,07760544 0,08429973 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,07760544 0,08426227 ! viral reproductive process GO:0022415 132 62 0,000 0,07882723 0,08555083 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,07882723 0,08551284 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,07882723 0,08547489 ! tRNA processing GO:0008033 102 62 0,000 0,07882723 0,08543696 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,07882723 0,08539908 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,08004743 0,08668256 ! mesoderm development GO:0007498 128 63 0,000 0,08004743 0,08664416 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,08004743 0,08660579 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,08004743 0,08656745 ! hydrogen transport GO:0006818 121 64 0,000 0,08126605 0,08784644 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,08126605 0,08780758 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,08126605 0,08776877 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,08126605 0,08772998 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,08248308 0,08900449 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,08248308 0,0889652 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,08248308 0,08892594 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,08248308 0,08888671 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,08248308 0,08884752 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,08248308 0,08880836 ! ear development GO:0043583 114 66 0,000 0,08369854 0,09007733 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,08369854 0,09003767 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,08369854 0,08999804 ! gonad development GO:0008406 115 66 0,000 0,08369854 0,08995844 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,08369854 0,08991888 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,08491243 0,09118288 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,08491243 0,09114282 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,08491243 0,09110279 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,08491243 0,0910628 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,08491243 0,09102284 ! secondary metabolic process GO:0019748 125 67 0,000 0,08491243 0,09098292 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,08491243 0,09094303 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,08612474 0,09220102 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,08612474 0,09216064 ! hexose catabolic process GO:0019320 113 68 0,000 0,08612474 0,09212028 ! extracellular matrix organization GO:0030198 146 68 0,000 0,08612474 0,09207997 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,08612474 0,09203969 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,08612474 0,09199945 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,08612474 0,09195924 ! viral reproduction GO:0016032 142 68 0,000 0,08612474 0,09191906 ! regulation of lipase activity GO:0060191 137 68 0,000 0,08612474 0,09187892 ! adaptive immune response GO:0002250 126 68 0,000 0,08612474 0,09183882 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,08612474 0,09179875 ! cell projection assembly GO:0030031 138 68 0,000 0,08612474 0,09175871 ! negative regulation of cell size GO:0045792 144 69 0,000 0,08733547 0,09300809 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,08733547 0,09296757 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,08733547 0,09292707 ! lung development GO:0030324 165 69 0,000 0,08733547 0,09288662 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,08733547 0,0928462 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,08733547 0,09280581 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,08733547 0,09276546 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,08733547 0,09272515 ! single fertilization GO:0007338 83 69 0,000 0,08733547 0,09268487 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,08854464 0,0939273 ! cell redox homeostasis GO:0045454 114 70 0,000 0,08854464 0,09388653 ! germ cell development GO:0007281 133 70 0,000 0,08854464 0,0938458 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,08854464 0,0938051 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,08975224 0,09504323 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,08975224 0,09500205 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,08975224 0,0949609 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,08975224 0,0949198 ! appendage morphogenesis GO:0035107 150 72 0,000 0,09095828 0,09615364 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,09095828 0,09611205 ! respiratory tube development GO:0030323 171 72 0,000 0,09095828 0,0960705 ! actin filament organization GO:0007015 167 72 0,000 0,09095828 0,09602898 ! B cell activation GO:0042113 179 72 0,000 0,09095828 0,0959875 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,09095828 0,09594606 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,09095828 0,09590465 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,09095828 0,09586327 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,09095828 0,09582194 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,09095828 0,09578063 ! appendage development GO:0048736 151 73 0,000 0,09216275 0,09700715 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,09216275 0,09696537 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,09216275 0,09692363 ! regulation of immune effector process GO:0002697 156 73 0,000 0,09216275 0,09688192 ! amino acid transport GO:0006865 148 74 0,000 0,09336565 0,09810421 ! regulation of caspase activity GO:0043281 136 74 0,000 0,09336565 0,09806203 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,09336565 0,09801989 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,09336565 0,09797779 ! respiratory system development GO:0060541 175 74 0,000 0,09336565 0,09793572 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,094567 0,0991533 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,094567 0,09911076 ! reproductive structure development GO:0048608 131 75 0,000 0,094567 0,09906826 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,094567 0,0990258 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,094567 0,09898337 ! eye development GO:0001654 155 75 0,000 0,094567 0,09894098 ! axon guidance GO:0007411 162 75 0,000 0,094567 0,09889862 ! rhythmic process GO:0048511 142 75 0,000 0,094567 0,09885631 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,09576679 0,1000677 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,09576679 0,10002491 ! learning or memory GO:0007611 161 76 0,000 0,09576679 0,09998217 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,09576679 0,09993946 ! regulation of blood pressure GO:0008217 134 76 0,000 0,09576679 0,09989679 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,09576679 0,09985415 ! neurotransmitter transport GO:0006836 142 77 0,000 0,09696503 0,10106039 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,09696503 0,1010173 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,09696503 0,10097424 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,09696503 0,10093121 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,09696503 0,10088823 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,09696503 0,10084528 ! regulation of catabolic process GO:0009894 173 77 0,000 0,09696503 0,10080237 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,09816171 0,102003 ! antigen processing and presentation GO:0019882 117 78 0,000 0,09816171 0,10195963 ! fertilization GO:0009566 99 78 0,000 0,09816171 0,1019163 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,09816171 0,101873 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,09935683 0,10306953 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,09935683 0,10302578 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,09935683 0,10298207 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,09935683 0,1029384 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,09935683 0,10289476 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,10055041 0,10408672 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,10055041 0,10404263 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,10055041 0,10399858 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,10055041 0,10395457 ! muscle cell differentiation GO:0042692 178 81 0,000 0,10174244 0,10514246 ! response to hypoxia GO:0001666 178 81 0,000 0,10174244 0,10509801 ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,10174244 0,10505359 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,10174244 0,1050092 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,10293292 0,10619305 ! protein import into nucleus GO:0006606 174 82 0,000 0,10293292 0,10614822 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,10412186 0,10732899 ! exocytosis GO:0006887 153 83 0,000 0,10412186 0,10728372 ! response to drug GO:0042493 149 83 0,000 0,10412186 0,1072385 ! response to oxygen levels GO:0070482 183 83 0,000 0,10412186 0,1071933 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,10412186 0,10714815 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,10412186 0,10710304 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,10412186 0,10705796 ! nuclear import GO:0051170 177 83 0,000 0,10412186 0,10701292 ! inorganic anion transport GO:0015698 156 83 0,000 0,10412186 0,10696792 ! response to metal ion GO:0010038 158 84 0,000 0,10530926 0,1081423 ! T cell activation GO:0042110 189 84 0,000 0,10530926 0,10809686 ! response to nutrient GO:0007584 135 84 0,000 0,10530926 0,10805146 ! digestion GO:0007586 130 84 0,000 0,10530926 0,1080061 ! regulation of ligase activity GO:0051340 147 84 0,000 0,10530926 0,10796077 ! negative regulation of transport GO:0051051 164 85 0,000 0,10649512 0,10913069 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,10649512 0,10908493 ! negative regulation of growth GO:0045926 168 85 0,000 0,10649512 0,10903922 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,10649512 0,10899353 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,10649512 0,10894789 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,10649512 0,10890229 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,10767943 0,1100673 ! regulation of lyase activity GO:0051339 169 86 0,000 0,10767943 0,11002127 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,10767943 0,10997527 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,10886222 0,11113681 ! mitochondrion organization GO:0007005 159 87 0,000 0,10886222 0,11109039 ! alcohol catabolic process GO:0046164 142 87 0,000 0,10886222 0,111044 ! nucleosome assembly GO:0006334 126 87 0,000 0,10886222 0,11099766 ! regulation of protein transport GO:0051223 165 87 0,000 0,10886222 0,11095135 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,11004346 0,1121085 ! amine biosynthetic process GO:0009309 146 88 0,000 0,11004346 0,11206177 ! sensory perception of smell GO:0007608 117 88 0,000 0,11004346 0,11201507 ! chromatin assembly GO:0031497 128 88 0,000 0,11004346 0,11196842 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,11004346 0,11192181 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,11122318 0,11307458 ! regulation of DNA binding GO:0051101 167 89 0,000 0,11122318 0,11302755 ! cellular defense response GO:0006968 123 89 0,000 0,11122318 0,11298055 ! protein localization in nucleus GO:0034504 192 89 0,000 0,11122318 0,11293359 ! regulation of neurological system process GO:0031644 175 89 0,000 0,11122318 0,11288667 ! response to inorganic substance GO:0010035 173 90 0,000 0,11240136 0,1140351 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,11240136 0,11398776 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,11240136 0,11394047 ! response to unfolded protein GO:0006986 139 90 0,000 0,11240136 0,11389321 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,11357802 0,11503777 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,11357802 0,11499009 ! defense response to bacterium GO:0042742 112 91 0,000 0,11357802 0,11494246 ! bone development GO:0060348 206 92 0,000 0,11475314 0,11608362 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,11475314 0,11603557 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,11475314 0,11598756 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,11592675 0,11712533 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,11592675 0,11707691 ! vitamin metabolic process GO:0006766 153 93 0,000 0,11592675 0,11702853 ! female pregnancy GO:0007565 166 94 0,000 0,11709883 0,11816292 ! sterol metabolic process GO:0016125 166 94 0,000 0,11709883 0,11811414 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,11709883 0,11806539 ! regulation of membrane potential GO:0042391 179 94 0,000 0,11709883 0,11801668 ! regulation of defense response GO:0031347 171 95 0,000 0,11826939 0,11914727 ! nucleosome organization GO:0034728 143 95 0,000 0,11826939 0,11909815 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,11826939 0,11904908 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,11826939 0,11900005 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,11826939 0,11895106 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,11826939 0,11890211 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,11826939 0,1188532 ! sex differentiation GO:0007548 171 96 0,000 0,11943843 0,11997865 ! response to protein stimulus GO:0051789 158 96 0,000 0,11943843 0,11992934 ! regulation of T cell activation GO:0050863 175 96 0,000 0,11943843 0,11988007 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,12060595 0,1210022 ! transcription initiation GO:0006352 171 97 0,000 0,12060595 0,12095252 ! regulation of protein localization GO:0032880 188 97 0,000 0,12060595 0,12090289 ! leukocyte differentiation GO:0002521 232 98 0,000 0,12177196 0,1220217 ! interphase of mitotic cell cycle GO:0051329 224 98 0,000 0,12177196 0,12197167 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,12177196 0,12192168 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,12409944 0,12420112 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,12409944 0,12415026 ! hormone metabolic process GO:0042445 171 100 0,000 0,12409944 0,12409944