pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-pos-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/88-Desmedt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of translation GO:0017148 22 16 2,000 2,515E-06 5,786E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 2,000 1,154E-05 0,01327623 ! placenta development GO:0001890 37 28 2,000 1,451E-05 0,01112623 ! Ras protein signal transduction GO:0007265 162 100 3,000 2,464E-05 0,01416691 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 1,000 2,838E-05 0,01305352 GO:0046516|hypusine metabolic process, ! enteric nervous system development GO:0048484 8 5 1,000 2,838E-05 0,01087794 ! negative regulation of translational initiation GO:0045947 7 6 1,000 4,252E-05 0,01397099 ! interaction with symbiont GO:0051702 8 6 1,000 4,252E-05 0,01222461 ! response to exogenous dsRNA GO:0043330 8 6 1,000 4,252E-05 0,01086632 ! regulation of smooth muscle cell migration GO:0014910 19 7 1,000 5,947E-05 0,01367695 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 1,000 5,947E-05 0,01243359 ! B cell receptor signaling pathway GO:0050853 11 7 1,000 5,947E-05 0,01139746 ! cell maturation GO:0048469 60 45 2,000 6,164E-05 0,01090473 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 1,000 7,92E-05 0,01301176 ! mitochondrion localization GO:0051646 12 8 1,000 7,92E-05 0,01214431 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 1,000 1,017E-04 0,01462261 GO:0010469|regulation of receptor activity, ! positive regulation of phagocytosis GO:0050766 11 9 1,000 1,017E-04 0,01376246 ! pyrimidine base metabolic process GO:0006206 14 9 1,000 1,017E-04 0,01299788 ! embryonic placenta development GO:0001892 12 9 1,000 1,017E-04 0,01231378 ! regulation of mitosis GO:0007088 84 54 2,000 1,066E-04 0,01226149 GO:0051783|regulation of nuclear division, ! developmental maturation GO:0021700 75 57 2,000 1,253E-04 0,01372774 ! polyamine metabolic process GO:0006595 14 10 1,000 1,27E-04 0,0132791 ! response to dsRNA GO:0043331 18 10 1,000 1,27E-04 0,01270174 ! T cell receptor signaling pathway GO:0050852 18 10 1,000 1,27E-04 0,0121725 ! regulation of phagocytosis GO:0050764 14 11 1,000 1,551E-04 0,01426716 ! biogenic amine catabolic process GO:0042402 21 11 1,000 1,551E-04 0,01371843 ! autonomic nervous system development GO:0048483 23 12 1,000 1,859E-04 0,01583549 ! peptidyl-lysine modification GO:0018205 18 12 1,000 1,859E-04 0,01526994 ! neuron maturation GO:0042551 21 14 1,000 2,558E-04 0,02028465 ! pituitary gland development GO:0021983 23 14 1,000 2,558E-04 0,0196085 ! cellular response to starvation GO:0009267 21 14 1,000 2,558E-04 0,01897597 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 2,558E-04 0,01838297 ! cell killing GO:0001906 20 14 1,000 2,558E-04 0,01782591 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 1,000 2,948E-04 0,01994211 ! cellular amino acid derivative catabolic process GO:0042219 27 15 1,000 2,948E-04 0,01937233 ! diencephalon development GO:0021536 25 16 1,000 3,366E-04 0,02150186 ! neural crest cell migration GO:0001755 24 16 1,000 3,366E-04 0,02092072 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 1,000 3,366E-04 0,02037018 ! regulation of cell cycle process GO:0010564 122 81 2,000 3,555E-04 0,02096397 ! nucleobase metabolic process GO:0009112 31 17 1,000 3,81E-04 0,0219085 ! positive regulation of angiogenesis GO:0045766 35 18 1,000 4,282E-04 0,02402027 ! peptide cross-linking GO:0018149 31 18 1,000 4,282E-04 0,02344836 ! cellular response to nutrient levels GO:0031669 27 18 1,000 4,282E-04 0,02290305 ! gut development GO:0048565 26 18 1,000 4,282E-04 0,02238253 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 1,000 4,781E-04 0,02443378 ! response to starvation GO:0042594 30 19 1,000 4,781E-04 0,02390261 ! response to lipopolysaccharide GO:0032496 26 19 1,000 4,781E-04 0,02339404 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 5,858E-04 0,02807104 ! platelet activation GO:0030168 28 21 1,000 5,858E-04 0,02749816 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 5,858E-04 0,0269482 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 6,4E-04 0,02886443 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 1,000 6,437E-04 0,02847252 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! ureteric bud development GO:0001657 32 22 1,000 6,437E-04 0,0279353 ! regulation of translation GO:0006417 151 100 2,000 6,591E-04 0,02807151 ! interaction with host GO:0051701 37 23 1,000 7,043E-04 0,0294518 ! cell fate determination GO:0001709 45 23 1,000 7,043E-04 0,02892588 ! response to molecule of bacterial origin GO:0002237 30 23 1,000 7,043E-04 0,02841841 ! liver development GO:0001889 40 23 1,000 7,043E-04 0,02792843 ! neural crest cell development GO:0014032 39 24 1,000 7,675E-04 0,02991906 GO:0014033|neural crest cell differentiation, ! insulin receptor signaling pathway GO:0008286 40 24 1,000 7,675E-04 0,02942041 ! positive regulation of nuclear division GO:0051785 39 25 1,000 8,333E-04 0,03142094 GO:0045840|positive regulation of mitosis, ! acute-phase response GO:0006953 42 27 1,000 9,729E-04 0,03609252 ! positive regulation of endocytosis GO:0045807 33 28 1,000 1,047E-03 0,03821114 ! immune response-activating signal transduction GO:0002757 38 28 1,000 1,047E-03 0,0376141 GO:0002764|immune response-regulating signal transduction, ! embryonic epithelial tube formation GO:0001838 44 30 1,000 1,202E-03 0,04252936 ! metanephros development GO:0001656 58 31 1,000 1,283E-03 0,04472591 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 1,283E-03 0,04405836 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 1,368E-03 0,04625515 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 1,543E-03 0,05144885 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 1,543E-03 0,05071387 ! protein homooligomerization GO:0051260 52 35 1,000 1,635E-03 0,0529734 ! mesenchymal cell development GO:0014031 64 38 1,000 1,926E-03 0,06152255 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of location in cell GO:0051651 69 38 1,000 1,926E-03 0,06067978 ! morphogenesis of embryonic epithelium GO:0016331 60 39 1,000 2,028E-03 0,06302829 ! regulation of cell shape GO:0008360 78 42 1,000 2,349E-03 0,07202838 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 2,461E-03 0,07446867 ! response to insulin stimulus GO:0032868 63 43 1,000 2,461E-03 0,07350155 ! epithelial tube morphogenesis GO:0060562 65 43 1,000 2,461E-03 0,07255922 ! negative regulation of cell migration GO:0030336 92 44 1,000 2,575E-03 0,07497237 ! positive regulation of cell cycle GO:0045787 77 45 1,000 2,692E-03 0,07739629 ! regulation of translational initiation GO:0006446 64 45 1,000 2,692E-03 0,07644078 ! endocrine system development GO:0035270 83 47 1,000 2,933E-03 0,08227397 ! regulation of endocytosis GO:0030100 63 48 1,000 3,058E-03 0,08472655 ! regulation of angiogenesis GO:0045765 94 49 1,000 3,184E-03 0,08718755 ! maintenance of location GO:0051235 84 49 1,000 3,184E-03 0,08616182 ! positive regulation of organelle organization GO:0010638 82 51 1,000 3,445E-03 0,09213278 ! negative regulation of cell motion GO:0051271 104 51 1,000 3,445E-03 0,09107378 ! kidney development GO:0001822 90 53 1,000 3,715E-03 0,0971058 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 4,285E-03 0,11073232 ! activation of MAPK activity GO:0000187 84 59 1,000 4,584E-03 0,11714283 ! regulation of vesicle-mediated transport GO:0060627 79 60 1,000 4,737E-03 0,11972325 ! meiosis GO:0007126 96 61 1,000 4,892E-03 0,12230616 GO:0051327|M phase of meiotic cell cycle, ! urogenital system development GO:0001655 101 61 1,000 4,892E-03 0,12099104 ! amine catabolic process GO:0009310 90 62 1,000 5,05E-03 0,12356266 ! meiotic cell cycle GO:0051321 97 62 1,000 5,05E-03 0,122262 ! organelle localization GO:0051640 96 62 1,000 5,05E-03 0,12098844 ! activation of immune response GO:0002253 83 65 1,000 5,537E-03 0,13128979 ! protein oligomerization GO:0051259 100 65 1,000 5,537E-03 0,1299501 ! cell-substrate adhesion GO:0031589 121 66 1,000 5,704E-03 0,13251655 ! acute inflammatory response GO:0002526 92 68 1,000 6,045E-03 0,13903023 ! tube morphogenesis GO:0035239 118 73 1,000 6,937E-03 0,15796249 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 7,122E-03 0,16058812 ! blood coagulation GO:0007596 116 75 1,000 7,309E-03 0,16321266 GO:0050817|coagulation, ! regulation of cell morphogenesis GO:0022604 140 76 1,000 7,499E-03 0,16583596 ! gland development GO:0048732 148 77 1,000 7,69E-03 0,1684579 ! nitrogen compound catabolic process GO:0044270 114 78 1,000 7,884E-03 0,17107834 ! forebrain development GO:0030900 131 80 1,000 8,279E-03 0,17796205 ! hemostasis GO:0007599 125 81 1,000 8,48E-03 0,18058625 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 8,552E-03 0,18045148 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 8,552E-03 0,17881102 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 8,552E-03 0,17720011 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 8,552E-03 0,17561796 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 8,552E-03 0,17406382 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 8,552E-03 0,17253695 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 8,552E-03 0,17103662 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 8,552E-03 0,16956217 ! sleep GO:0030431 11 5 0,000 8,552E-03 0,16811292 ! negative regulation of bone resorption GO:0045779 10 5 0,000 8,552E-03 0,16668824 ! nucleotide-sugar transport GO:0015780 8 5 0,000 8,552E-03 0,16528749 ! regulation of interferon-beta production GO:0032648 5 5 0,000 8,552E-03 0,1639101 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 8,552E-03 0,16255547 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 8,552E-03 0,16122305 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 8,552E-03 0,15991229 ! tongue development GO:0043586 6 5 0,000 8,552E-03 0,15862268 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 8,552E-03 0,15735369 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 8,552E-03 0,15610486 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 8,552E-03 0,15487568 ! cobalt ion transport GO:0006824 9 5 0,000 8,552E-03 0,15366572 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 8,552E-03 0,15247451 ! SMAD protein complex assembly GO:0007183 9 5 0,000 8,552E-03 0,15130163 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 8,552E-03 0,15014666 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 8,552E-03 0,14900918 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 8,552E-03 0,14788881 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 8,552E-03 0,14678516 ! embryonic camera-type eye development GO:0031076 8 5 0,000 8,552E-03 0,14569787 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 8,552E-03 0,14462656 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 8,552E-03 0,14357089 ! adaptation of signaling pathway GO:0022401 7 5 0,000 8,552E-03 0,14253052 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 8,552E-03 0,14150512 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 8,552E-03 0,14049437 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 8,552E-03 0,13949796 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 8,552E-03 0,13851558 ! positive regulation of histone modification GO:0031058 5 5 0,000 8,552E-03 0,13754694 ! malate metabolic process GO:0006108 7 5 0,000 8,552E-03 0,13659175 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 8,552E-03 0,13564974 ! behavioral response to pain GO:0048266 7 5 0,000 8,552E-03 0,13472063 ! clathrin coat assembly GO:0048268 11 5 0,000 8,552E-03 0,13380416 ! phototransduction, visible light GO:0007603 6 5 0,000 8,552E-03 0,13290008 ! regulation of dopamine uptake GO:0051584 9 5 0,000 8,552E-03 0,13200813 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 8,552E-03 0,13112808 ! mating behavior GO:0007617 6 5 0,000 8,552E-03 0,13025968 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 8,552E-03 0,12940271 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 8,552E-03 0,12855694 ! rhythmic behavior GO:0007622 12 5 0,000 8,552E-03 0,12772215 ! copulation GO:0007620 7 5 0,000 8,552E-03 0,12689814 ! glial cell fate commitment GO:0021781 12 5 0,000 8,552E-03 0,12608469 ! protein maturation by protein folding GO:0022417 12 5 0,000 8,552E-03 0,1252816 ! embryonic hemopoiesis GO:0035162 10 5 0,000 8,552E-03 0,12448868 ! regulation of potassium ion transport GO:0043266 9 5 0,000 8,552E-03 0,12370573 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 8,552E-03 0,12293257 ! apoptotic cell clearance GO:0043277 13 5 0,000 8,552E-03 0,12216902 ! lipoprotein particle clearance GO:0034381 9 5 0,000 8,552E-03 0,12141489 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 8,552E-03 0,12067001 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 8,552E-03 0,11993422 ! response to protozoan GO:0001562 9 5 0,000 8,552E-03 0,11920734 ! positive regulation of glycolysis GO:0045821 11 5 0,000 8,552E-03 0,11848923 ! lymph vessel development GO:0001945 7 5 0,000 8,552E-03 0,11777971 ! endochondral ossification GO:0001958 12 5 0,000 8,552E-03 0,11707864 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 8,552E-03 0,11638587 ! parathyroid gland development GO:0060017 8 5 0,000 8,552E-03 0,11570125 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 8,552E-03 0,11502463 ! anagen GO:0042640 6 5 0,000 8,552E-03 0,11435588 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 8,552E-03 0,11369487 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 8,552E-03 0,11304145 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 8,552E-03 0,1123955 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 8,552E-03 0,11175689 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 8,552E-03 0,11112549 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 8,552E-03 0,11050119 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 8,552E-03 0,10988386 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 8,552E-03 0,1092734 ! epithelial cell proliferation GO:0050673 6 5 0,000 8,552E-03 0,10866968 ! cardiac muscle fiber development GO:0048739 7 5 0,000 8,552E-03 0,10807259 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 8,552E-03 0,10748203 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 8,552E-03 0,10689789 ! neutrophil mediated immunity GO:0002446 6 5 0,000 8,552E-03 0,10632006 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 8,552E-03 0,10574845 ! ovulation GO:0030728 6 5 0,000 8,552E-03 0,10518295 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 8,552E-03 0,10462347 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 8,552E-03 0,1040699 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 8,552E-03 0,10352217 ! response to pH GO:0009268 9 5 0,000 8,552E-03 0,10298017 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 8,552E-03 0,10244381 ! proline biosynthetic process GO:0006561 6 5 0,000 8,552E-03 0,10191301 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 8,552E-03 0,10138769 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 8,552E-03 0,10086775 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 8,552E-03 0,10035312 ! polyol catabolic process GO:0046174 7 5 0,000 8,552E-03 0,09984371 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 8,552E-03 0,09933945 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 8,552E-03 0,09884026 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 8,552E-03 0,09834606 ! sister chromatid cohesion GO:0007062 9 5 0,000 8,552E-03 0,09785678 ! nerve growth factor processing GO:0032455 7 5 0,000 8,552E-03 0,09737234 ! urea metabolic process GO:0019627 6 5 0,000 8,552E-03 0,09689267 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 8,552E-03 0,0964177 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 8,552E-03 0,09594737 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 8,552E-03 0,09548161 ! neutrophil activation GO:0042119 5 5 0,000 8,552E-03 0,09502035 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 8,552E-03 0,09456352 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 8,552E-03 0,09411106 ! response to food GO:0032094 5 5 0,000 8,552E-03 0,09366291 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 8,552E-03 0,09321901 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 8,552E-03 0,0927793 ! paraxial mesoderm development GO:0048339 9 5 0,000 8,552E-03 0,09234372 ! forebrain neuron development GO:0021884 7 5 0,000 8,552E-03 0,0919122 ! melanosome organization GO:0032438 7 5 0,000 8,552E-03 0,09148471 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 8,552E-03 0,09106117 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 8,552E-03 0,09064153 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 8,552E-03 0,09022574 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 8,552E-03 0,08981375 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 8,552E-03 0,08940551 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 8,552E-03 0,08900096 ! nucleoside transport GO:0015858 6 5 0,000 8,552E-03 0,08860005 ! nucleoside salvage GO:0043174 7 5 0,000 8,552E-03 0,08820274 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 8,552E-03 0,08780898 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 8,552E-03 0,08741872 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 8,552E-03 0,08703191 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 8,552E-03 0,08664851 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 8,552E-03 0,08626847 ! early endosome to late endosome transport GO:0045022 11 5 0,000 8,552E-03 0,08589175 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 8,552E-03 0,08551831 ! depyrimidination GO:0045008 8 5 0,000 8,552E-03 0,0851481 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 8,552E-03 0,08478109 ! 5S class rRNA transcription GO:0042791 8 5 0,000 8,552E-03 0,08441722 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 8,552E-03 0,08405646 ! regulation of centrosome cycle GO:0046605 7 5 0,000 8,552E-03 0,08369877 ! neuronal ion channel clustering GO:0045161 7 5 0,000 8,552E-03 0,08334412 ! sodium ion homeostasis GO:0055078 6 5 0,000 8,552E-03 0,08299245 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 8,552E-03 0,08264375 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 8,552E-03 0,08229796 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 8,552E-03 0,08195505 ! monocyte differentiation GO:0030224 8 5 0,000 8,552E-03 0,08161499 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 8,552E-03 0,08127773 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 8,552E-03 0,08094326 ! centrosome duplication GO:0051298 5 5 0,000 8,552E-03 0,08061152 ! response to UV-C GO:0010225 6 5 0,000 8,552E-03 0,0802825 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 8,552E-03 0,07995615 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 8,552E-03 0,07963244 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 8,552E-03 0,07931134 ! regulation of dendrite development GO:0050773 12 5 0,000 8,552E-03 0,07899282 ! peptidyl-arginine modification GO:0018195 7 5 0,000 8,552E-03 0,07867685 ! positive regulation of organ growth GO:0046622 6 5 0,000 8,552E-03 0,07836339 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 8,552E-03 0,07805243 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 8,552E-03 0,07774392 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 8,552E-03 0,07743784 ! regulation of dopamine secretion GO:0014059 12 5 0,000 8,552E-03 0,07713416 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 8,552E-03 0,07683286 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 8,552E-03 0,0765339 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 8,552E-03 0,07623726 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 8,552E-03 0,0759429 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 8,552E-03 0,07565081 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 8,552E-03 0,07536096 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 8,552E-03 0,07507333 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 8,552E-03 0,07478788 ! neural tube patterning GO:0021532 6 5 0,000 8,552E-03 0,07450459 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 8,552E-03 0,07422344 ! histone demethylation GO:0016577 9 5 0,000 8,552E-03 0,07394441 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 8,552E-03 0,07366746 ! regulation of sterol transport GO:0032371 7 5 0,000 8,552E-03 0,07339258 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 8,552E-03 0,07311975 ! establishment of planar polarity GO:0001736 6 5 0,000 8,552E-03 0,07284893 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 8,552E-03 0,07258012 ! muscle cell proliferation GO:0033002 8 5 0,000 8,552E-03 0,07231328 ! transcription termination GO:0006353 8 5 0,000 8,552E-03 0,07204839 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 8,552E-03 0,07178544 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 8,552E-03 0,07152441 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 8,552E-03 0,07126526 ! regulation of respiratory burst GO:0060263 8 5 0,000 8,552E-03 0,07100798 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 8,552E-03 0,07075256 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 8,552E-03 0,07049897 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 8,552E-03 0,07024719 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 8,552E-03 0,0699972 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 8,552E-03 0,06974898 ! apical protein localization GO:0045176 6 5 0,000 8,552E-03 0,06950252 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 8,552E-03 0,06925779 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 8,552E-03 0,06901478 ! galactolipid metabolic process GO:0019374 7 5 0,000 8,552E-03 0,06877347 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 8,552E-03 0,06853384 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 8,552E-03 0,06829587 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 8,552E-03 0,06805956 ! triglyceride catabolic process GO:0019433 6 5 0,000 8,552E-03 0,06782487 ! glial cell migration GO:0008347 10 5 0,000 8,552E-03 0,06759179 ! determination of adult lifespan GO:0008340 8 5 0,000 8,552E-03 0,06736031 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 8,552E-03 0,06713042 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 8,552E-03 0,06690208 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 8,552E-03 0,06667529 ! somatic stem cell maintenance GO:0035019 13 5 0,000 8,552E-03 0,06645004 ! cerebellar cortex formation GO:0021697 6 5 0,000 8,552E-03 0,0662263 ! neural plate development GO:0001840 6 5 0,000 8,552E-03 0,06600407 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 8,552E-03 0,06578332 ! regulation of sensory perception GO:0051931 6 5 0,000 8,552E-03 0,06556404 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 8,552E-03 0,06534622 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 8,552E-03 0,06512984 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 8,552E-03 0,06491489 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 8,552E-03 0,06470135 ! sensory cilium assembly GO:0035058 6 5 0,000 8,552E-03 0,06448922 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 8,552E-03 0,06427847 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 8,552E-03 0,06406909 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 8,552E-03 0,06386108 ! spindle assembly GO:0051225 5 5 0,000 8,552E-03 0,06365441 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 8,552E-03 0,06344907 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 8,552E-03 0,06324505 ! protein amino acid prenylation GO:0018346 9 5 0,000 8,552E-03 0,06304235 ! organ regeneration GO:0031100 7 5 0,000 8,552E-03 0,06284093 ! NAD biosynthetic process GO:0009435 7 5 0,000 8,552E-03 0,0626408 ! carnitine metabolic process GO:0009437 5 5 0,000 8,552E-03 0,06244194 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 8,552E-03 0,06224434 ! cellular anion homeostasis GO:0030002 6 5 0,000 8,552E-03 0,06204799 GO:0055081|anion homeostasis, ! biogenic amine metabolic process GO:0006576 121 83 1,000 8,887E-03 0,06428017 ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 9,304E-03 0,06708088 ! tRNA transcription GO:0009304 11 6 0,000 0,01025369 0,07369842 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01025369 0,07346883 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01025369 0,07324067 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01025369 0,07301392 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01025369 0,07278856 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01025369 0,0725646 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01025369 0,07234201 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01025369 0,07212078 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01025369 0,0719009 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01025369 0,07168235 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01025369 0,07146514 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01025369 0,07124923 ! prostate gland development GO:0030850 9 6 0,000 0,01025369 0,07103462 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01025369 0,07082131 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01025369 0,07060927 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01025369 0,07039849 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01025369 0,07018897 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01025369 0,0699807 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01025369 0,06977365 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01025369 0,06956783 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01025369 0,06936322 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01025369 0,06915981 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01025369 0,06895759 ! neuron adhesion GO:0007158 9 6 0,000 0,01025369 0,06875654 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01025369 0,06855667 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01025369 0,06835796 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01025369 0,06816039 ! signal peptide processing GO:0006465 8 6 0,000 0,01025369 0,06796396 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01025369 0,06776866 ! mRNA stabilization GO:0048255 15 6 0,000 0,01025369 0,06757448 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01025369 0,06738141 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01025369 0,06718944 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01025369 0,06699856 ! opsonization GO:0008228 8 6 0,000 0,01025369 0,06680877 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01025369 0,06662004 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01025369 0,06643238 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01025369 0,06624577 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01025369 0,06606021 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01025369 0,06587568 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01025369 0,06569219 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01025369 0,06550971 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01025369 0,06532824 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01025369 0,06514778 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01025369 0,06496831 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01025369 0,06478982 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01025369 0,06461231 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01025369 0,06443578 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01025369 0,0642602 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01025369 0,06408558 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01025369 0,06391191 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01025369 0,06373918 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01025369 0,06356737 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01025369 0,06339649 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01025369 0,06322653 ! thymic T cell selection GO:0045061 12 6 0,000 0,01025369 0,06305747 ! protein lipoylation GO:0009249 10 6 0,000 0,01025369 0,06288932 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01025369 0,06272206 ! pigment granule organization GO:0048753 11 6 0,000 0,01025369 0,06255569 ! drug transport GO:0015893 6 6 0,000 0,01025369 0,0623902 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01025369 0,06222558 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01025369 0,06206183 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01025369 0,06189894 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01025369 0,0617369 ! histidine metabolic process GO:0006547 6 6 0,000 0,01025369 0,0615757 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01025369 0,06141535 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01025369 0,06125583 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01025369 0,06109714 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01025369 0,06093926 ! adenohypophysis development GO:0021984 10 6 0,000 0,01025369 0,0607822 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01025369 0,06062595 ! hyperosmotic response GO:0006972 8 6 0,000 0,01025369 0,0604705 ! microtubule nucleation GO:0007020 10 6 0,000 0,01025369 0,06031584 ! ER overload response GO:0006983 7 6 0,000 0,01025369 0,06016198 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01025369 0,06000889 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01025369 0,05985659 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01025369 0,05970505 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01025369 0,05955428 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01025369 0,05940427 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01025369 0,05925501 ! response to dietary excess GO:0002021 7 6 0,000 0,01025369 0,0591065 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01025369 0,05895874 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01025369 0,05881171 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01025369 0,05866541 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01025369 0,05851984 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01025369 0,05837499 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01025369 0,05823085 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01025369 0,05808743 ! neuron apoptosis GO:0051402 8 6 0,000 0,01025369 0,0579447 ! organic alcohol transport GO:0015850 9 6 0,000 0,01025369 0,05780268 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01025369 0,05766136 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01025369 0,05752072 ! male sex determination GO:0030238 9 6 0,000 0,01025369 0,05738077 ! carnitine transport GO:0015879 8 6 0,000 0,01025369 0,05724149 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01025369 0,05710289 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01025369 0,05696496 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01025369 0,0568277 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01025369 0,05669109 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01025369 0,05655514 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01025369 0,05641984 ! parturition GO:0007567 12 6 0,000 0,01025369 0,05628519 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01025369 0,05615118 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01025369 0,0560178 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01025369 0,05588506 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01025369 0,05575294 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01025369 0,05562145 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01025369 0,05549058 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01025369 0,05536032 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01025369 0,05523067 ! macrophage differentiation GO:0030225 10 6 0,000 0,01025369 0,05510162 ! astrocyte development GO:0014002 14 6 0,000 0,01025369 0,05497318 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01025369 0,05484534 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01025369 0,05471809 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01025369 0,05459142 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01025369 0,05446535 ! eating behavior GO:0042755 6 6 0,000 0,01025369 0,05433985 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01025369 0,05421493 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01025369 0,05409058 ! response to copper ion GO:0046688 9 6 0,000 0,01025369 0,05396681 ! DNA topological change GO:0006265 8 6 0,000 0,01025369 0,0538436 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01025369 0,05372094 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01025369 0,05359885 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01025369 0,05347731 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01025369 0,05335632 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01025369 0,05323588 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01025369 0,05311598 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01025369 0,05299662 ! gas homeostasis GO:0033483 11 6 0,000 0,01025369 0,05287779 ! hair follicle maturation GO:0048820 7 6 0,000 0,01025369 0,0527595 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01025369 0,05264173 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01025369 0,05252449 ! Schwann cell development GO:0014044 14 6 0,000 0,01025369 0,05240777 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01025369 0,05229156 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01025369 0,05217587 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01025369 0,05206069 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01025369 0,05194602 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01025369 0,05183186 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01025369 0,05171819 ! histone ubiquitination GO:0016574 7 6 0,000 0,01025369 0,05160502 ! regulation of meiosis GO:0040020 10 6 0,000 0,01025369 0,05149235 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01025369 0,05138016 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01025369 0,05126847 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01025369 0,05115726 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01025369 0,05104653 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01025369 0,05093627 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01025369 0,0508265 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01025369 0,05071719 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01025369 0,05060836 ! receptor internalization GO:0031623 9 6 0,000 0,01025369 0,05049999 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01025369 0,05039208 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01025369 0,05028464 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01025369 0,05017765 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01025369 0,05007111 ! protein deubiquitination GO:0016579 8 6 0,000 0,01025369 0,04996503 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01025369 0,0498594 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01025369 0,04975421 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01025369 0,04964946 ! axonal fasciculation GO:0007413 9 6 0,000 0,01025369 0,04954516 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01025369 0,04944129 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01025369 0,04933786 ! midbrain development GO:0030901 6 6 0,000 0,01025369 0,04923485 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01025369 0,04913228 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01025369 0,04903013 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01025369 0,04892841 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01025369 0,04882711 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01025369 0,04872623 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01025369 0,04862576 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01025369 0,04852571 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01025369 0,04842607 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01025369 0,04832683 ! adult feeding behavior GO:0008343 6 6 0,000 0,01025369 0,04822801 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01025369 0,04812958 ! blastocyst growth GO:0001832 15 6 0,000 0,01025369 0,04803156 ! pigment granule transport GO:0051904 12 6 0,000 0,01025369 0,04793393 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01025369 0,0478367 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01025369 0,04773987 ! catecholamine transport GO:0051937 7 6 0,000 0,01025369 0,04764342 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01025369 0,04754737 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01025369 0,0474517 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01025369 0,04735642 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01025369 0,04726151 ! protein prenylation GO:0018342 10 6 0,000 0,01025369 0,04716699 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01025369 0,04707284 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01025369 0,04697907 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01025369 0,04688568 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01025369 0,04679265 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01025369 0,04669999 ! cell fate commitment GO:0045165 141 92 1,000 0,01082855 0,04922069 ! positive regulation of immune response GO:0050778 121 92 1,000 0,01082855 0,04912361 ! peptidyl-amino acid modification GO:0018193 147 93 1,000 0,01105482 0,05005137 ! in utero embryonic development GO:0001701 147 96 1,000 0,01174615 0,05307693 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,01195273 0,05390448 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01195273 0,05379899 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01195273 0,05369391 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01195273 0,05358924 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01195273 0,05348499 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01195273 0,05338113 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01195273 0,05327768 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01195273 0,05317463 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01195273 0,05307197 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01195273 0,05296972 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01195273 0,05286785 ! reproductive behavior GO:0019098 12 7 0,000 0,01195273 0,05276638 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01195273 0,05266529 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01195273 0,05256459 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01195273 0,05246428 ! oligopeptide transport GO:0006857 11 7 0,000 0,01195273 0,05236435 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01195273 0,0522648 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01195273 0,05216562 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,01195273 0,05206682 ! RNA methylation GO:0001510 11 7 0,000 0,01195273 0,0519684 ! pericardium development GO:0060039 8 7 0,000 0,01195273 0,05187034 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01195273 0,05177266 ! fibril organization GO:0043206 13 7 0,000 0,01195273 0,05167534 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01195273 0,05157839 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01195273 0,0514818 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01195273 0,05138557 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01195273 0,05128971 ! lipoprotein transport GO:0042953 9 7 0,000 0,01195273 0,05119419 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01195273 0,05109904 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01195273 0,05100423 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01195273 0,05090978 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01195273 0,05081568 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01195273 0,05072192 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01195273 0,05062851 ! chemosensory behavior GO:0007635 9 7 0,000 0,01195273 0,05053545 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01195273 0,05044272 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01195273 0,05035033 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01195273 0,05025829 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01195273 0,05016657 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01195273 0,0500752 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01195273 0,04998415 ! reflex GO:0060004 12 7 0,000 0,01195273 0,04989343 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01195273 0,04980305 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01195273 0,04971299 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01195273 0,04962325 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01195273 0,04953384 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01195273 0,04944475 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01195273 0,04935598 ! spinal cord patterning GO:0021511 7 7 0,000 0,01195273 0,04926753 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01195273 0,0491794 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01195273 0,04909158 ! adrenal gland development GO:0030325 17 7 0,000 0,01195273 0,04900407 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01195273 0,04891687 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01195273 0,04882999 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01195273 0,04874341 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01195273 0,04865714 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01195273 0,04857117 ! endosome organization GO:0007032 10 7 0,000 0,01195273 0,04848551 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01195273 0,04840014 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01195273 0,04831508 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01195273 0,04823032 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01195273 0,04814585 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01195273 0,04806168 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01195273 0,04797781 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01195273 0,04789422 ! galactose metabolic process GO:0006012 10 7 0,000 0,01195273 0,04781093 ! vesicle fusion GO:0006906 15 7 0,000 0,01195273 0,04772792 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01195273 0,0476452 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01195273 0,04756277 ! organ growth GO:0035265 11 7 0,000 0,01195273 0,04748063 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01195273 0,04739876 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01195273 0,04731718 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01195273 0,04723588 ! retinol metabolic process GO:0042572 9 7 0,000 0,01195273 0,04715486 ! behavioral fear response GO:0001662 13 7 0,000 0,01195273 0,04707411 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01195273 0,04699365 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01195273 0,04691345 ! rRNA modification GO:0000154 12 7 0,000 0,01195273 0,04683353 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01195273 0,04675388 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01195273 0,0466745 ! response to UV-B GO:0010224 11 7 0,000 0,01195273 0,04659539 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01195273 0,04651655 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01195273 0,04643798 ! intermediate filament organization GO:0045109 11 7 0,000 0,01195273 0,04635967 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01195273 0,04628162 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01195273 0,04620384 ! fibrinolysis GO:0042730 9 7 0,000 0,01195273 0,04612631 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01195273 0,04604905 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01195273 0,04597204 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01195273 0,0458953 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01195273 0,0458188 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01195273 0,04574257 ! response to tropane GO:0014073 13 7 0,000 0,01195273 0,04566658 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01195273 0,04559085 ! melanosome localization GO:0032400 10 7 0,000 0,01195273 0,04551537 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01195273 0,04544014 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01195273 0,04536515 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01195273 0,04529042 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01195273 0,04521592 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01195273 0,04514168 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01195273 0,04506768 ! mast cell activation GO:0045576 9 7 0,000 0,01195273 0,04499392 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01195273 0,0449204 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,01195273 0,04484712 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01195273 0,04477408 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01195273 0,04470127 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01195273 0,04462871 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01195273 0,04455637 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01195273 0,04448428 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01195273 0,04441241 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01195273 0,04434078 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01195273 0,04426938 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01195273 0,0441982 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01195273 0,04412726 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01195273 0,04405654 ! response to tumor cell GO:0002347 12 7 0,000 0,01195273 0,04398605 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01195273 0,04391579 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01195273 0,04384575 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,01195273 0,04377593 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01195273 0,04370633 ! diuresis GO:0030146 12 7 0,000 0,01195273 0,04363696 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01195273 0,0435678 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01195273 0,04349886 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01195273 0,04343015 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01195273 0,04336164 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01195273 0,04329336 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01195273 0,04322529 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01195273 0,04315743 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01195273 0,04308978 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01195273 0,04302235 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01195273 0,04295513 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01195273 0,04288812 ! lymph node development GO:0048535 9 7 0,000 0,01195273 0,04282131 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01195273 0,04275472 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01195273 0,04268833 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01195273 0,04262214 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01195273 0,04255616 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01195273 0,04249039 ! ATP catabolic process GO:0006200 10 7 0,000 0,01195273 0,04242482 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01195273 0,04235945 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01195273 0,04229428 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01195273 0,04222931 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01195273 0,04216454 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01195273 0,04209997 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01195273 0,0420356 ! muscle adaptation GO:0043500 12 7 0,000 0,01195273 0,04197142 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01195273 0,04190744 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01195273 0,04184366 ! retina homeostasis GO:0001895 9 7 0,000 0,01195273 0,04178006 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01195273 0,04171667 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01195273 0,04165346 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01195273 0,04159044 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01195273 0,04152762 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01195273 0,04146498 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01195273 0,04140253 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,01269687 0,04391397 ! regulation of body fluid levels GO:0050878 154 100 1,000 0,01269687 0,04384803 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01364895 0,04706534 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01364895 0,04699489 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01364895 0,04692464 ! axon extension GO:0048675 11 8 0,000 0,01364895 0,0468546 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01364895 0,04678478 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01364895 0,04671516 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01364895 0,04664574 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01364895 0,04657654 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01364895 0,04650753 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,01364895 0,04643873 ! phosphate transport GO:0006817 10 8 0,000 0,01364895 0,04637014 ! N-glycan processing GO:0006491 12 8 0,000 0,01364895 0,04630175 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01364895 0,04623356 ! UTP metabolic process GO:0046051 8 8 0,000 0,01364895 0,04616557 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01364895 0,04609778 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01364895 0,04603018 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01364895 0,04596279 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01364895 0,04589559 ! succinate metabolic process GO:0006105 14 8 0,000 0,01364895 0,04582859 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01364895 0,04576179 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01364895 0,04569517 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01364895 0,04562876 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01364895 0,04556253 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01364895 0,0454965 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01364895 0,04543066 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01364895 0,04536501 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01364895 0,04529955 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01364895 0,04523427 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01364895 0,04516919 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01364895 0,04510429 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01364895 0,04503958 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01364895 0,04497505 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01364895 0,04491071 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01364895 0,04484655 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01364895 0,04478257 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01364895 0,04471878 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01364895 0,04465517 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01364895 0,04459174 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01364895 0,04452849 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01364895 0,04446542 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01364895 0,04440252 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01364895 0,04433981 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01364895 0,04427727 ! melanin metabolic process GO:0006582 12 8 0,000 0,01364895 0,04421491 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01364895 0,04415272 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01364895 0,04409071 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01364895 0,04402887 ! macrophage activation GO:0042116 12 8 0,000 0,01364895 0,04396721 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01364895 0,04390571 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01364895 0,04384439 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01364895 0,04378324 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01364895 0,04372226 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01364895 0,04366145 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01364895 0,04360081 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01364895 0,04354034 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01364895 0,04348003 ! ruffle organization GO:0031529 11 8 0,000 0,01364895 0,0434199 ! osteoblast development GO:0002076 13 8 0,000 0,01364895 0,04335992 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01364895 0,04330012 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01364895 0,04324048 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01364895 0,043181 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01364895 0,04312168 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01364895 0,04306253 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01364895 0,04300354 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01364895 0,04294471 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01364895 0,04288604 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01364895 0,04282754 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01364895 0,04276919 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01364895 0,042711 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01364895 0,04265297 ! segment specification GO:0007379 10 8 0,000 0,01364895 0,04259509 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01364895 0,04253738 ! cellular extravasation GO:0045123 11 8 0,000 0,01364895 0,04247982 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01364895 0,04242241 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01364895 0,04236516 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01364895 0,04230807 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01364895 0,04225112 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01364895 0,04219433 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01364895 0,0421377 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01364895 0,04208121 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01364895 0,04202488 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01364895 0,0419687 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01364895 0,04191266 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01364895 0,04185678 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01364895 0,04180105 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01364895 0,04174546 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01364895 0,04169002 ! icosanoid secretion GO:0032309 12 8 0,000 0,01364895 0,04163473 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01364895 0,04157958 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01364895 0,04152458 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01364895 0,04146973 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01364895 0,04141502 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01364895 0,04136045 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01364895 0,04130603 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01364895 0,04125175 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01364895 0,04119762 ! sterol catabolic process GO:0016127 9 8 0,000 0,01364895 0,04114362 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01364895 0,04108977 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01364895 0,04103606 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01364895 0,04098249 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01364895 0,04092905 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01364895 0,04087576 ! prophase GO:0051324 11 8 0,000 0,01364895 0,04082261 ! S phase GO:0051320 8 8 0,000 0,01364895 0,04076959 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01364895 0,04071671 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01364895 0,04066397 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01364895 0,04061136 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01364895 0,0405589 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01364895 0,04050656 ! hormone catabolic process GO:0042447 13 8 0,000 0,01364895 0,04045436 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01364895 0,0404023 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01364895 0,04035037 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01364895 0,04029857 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01364895 0,0402469 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01364895 0,04019537 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01364895 0,04014397 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01364895 0,0400927 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01364895 0,04004156 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01364895 0,03999055 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01364895 0,03993968 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01364895 0,03988893 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01364895 0,03983831 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01364895 0,03978781 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01364895 0,03973745 GO:0000076|DNA replication checkpoint, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01364895 0,03968721 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01534235 0,04455481 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01534235 0,04449863 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01534235 0,04444259 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01534235 0,04438668 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01534235 0,04433092 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01534235 0,0442753 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01534235 0,04421982 ! CTP metabolic process GO:0046036 9 9 0,000 0,01534235 0,04416447 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01534235 0,04410927 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01534235 0,0440542 ! GTP metabolic process GO:0046039 9 9 0,000 0,01534235 0,04399927 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01534235 0,04394447 ! social behavior GO:0035176 14 9 0,000 0,01534235 0,04388982 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01534235 0,0438353 ! artery development GO:0060840 19 9 0,000 0,01534235 0,04378091 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01534235 0,04372666 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01534235 0,04367254 ! response to pain GO:0048265 16 9 0,000 0,01534235 0,04361856 ! protein complex disassembly GO:0043241 17 9 0,000 0,01534235 0,04356471 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01534235 0,04351099 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01534235 0,0434574 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01534235 0,04340395 ! lung alveolus development GO:0048286 17 9 0,000 0,01534235 0,04335063 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01534235 0,04329744 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01534235 0,04324438 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01534235 0,04319145 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01534235 0,04313865 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01534235 0,04308597 ! protein targeting to ER GO:0045047 19 9 0,000 0,01534235 0,04303343 ! T cell selection GO:0045058 18 9 0,000 0,01534235 0,04298101 ! endoderm development GO:0007492 12 9 0,000 0,01534235 0,04292873 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01534235 0,04287656 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01534235 0,04282453 ! arginine catabolic process GO:0006527 10 9 0,000 0,01534235 0,04277262 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01534235 0,04272084 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01534235 0,04266918 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01534235 0,04261765 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01534235 0,04256624 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01534235 0,04251496 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01534235 0,04246379 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01534235 0,04241276 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01534235 0,04236184 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01534235 0,04231105 ! mannose metabolic process GO:0006013 9 9 0,000 0,01534235 0,04226037 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01534235 0,04220982 ! receptor clustering GO:0043113 15 9 0,000 0,01534235 0,04215939 ! epithelial cell development GO:0002064 10 9 0,000 0,01534235 0,04210908 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01534235 0,04205889 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01534235 0,04200882 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01534235 0,04195887 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01534235 0,04190904 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01534235 0,04185933 ! motor axon guidance GO:0008045 14 9 0,000 0,01534235 0,04180973 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01534235 0,04176025 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01534235 0,04171089 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01534235 0,04166164 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01534235 0,04161252 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01534235 0,0415635 ! DNA ligation GO:0006266 14 9 0,000 0,01534235 0,0415146 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01534235 0,04146582 ! response to amine stimulus GO:0014075 13 9 0,000 0,01534235 0,04141715 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01534235 0,0413686 ! erythrocyte development GO:0048821 11 9 0,000 0,01534235 0,04132016 ! renal water homeostasis GO:0003091 14 9 0,000 0,01534235 0,04127183 ! postreplication repair GO:0006301 11 9 0,000 0,01534235 0,04122361 ! mRNA cleavage GO:0006379 13 9 0,000 0,01534235 0,04117551 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01534235 0,04112752 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01534235 0,04107964 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01534235 0,04103188 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01534235 0,04098422 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01534235 0,04093667 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01534235 0,04088924 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01534235 0,04084191 ! acid secretion GO:0046717 14 9 0,000 0,01534235 0,0407947 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01534235 0,04074759 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01534235 0,04070059 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01534235 0,0406537 ! purine base metabolic process GO:0006144 18 9 0,000 0,01534235 0,04060692 ! oocyte differentiation GO:0009994 12 9 0,000 0,01534235 0,04056024 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01534235 0,04051368 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01534235 0,04046722 ! spleen development GO:0048536 15 9 0,000 0,01534235 0,04042086 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01534235 0,04037461 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01534235 0,04032847 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01534235 0,04028243 ! detection of calcium ion GO:0005513 13 9 0,000 0,01534235 0,0402365 ! blastocyst formation GO:0001825 12 9 0,000 0,01534235 0,04019068 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01534235 0,04014495 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01534235 0,04009933 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01534235 0,04005382 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01534235 0,0400084 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01534235 0,03996309 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01534235 0,03991789 ! prepulse inhibition GO:0060134 14 9 0,000 0,01534235 0,03987278 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01534235 0,03982778 ! insulin secretion GO:0030073 17 9 0,000 0,01534235 0,03978288 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01534235 0,03973808 ! response to nicotine GO:0035094 16 9 0,000 0,01534235 0,03969338 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01534235 0,03964878 ! nucleus localization GO:0051647 15 9 0,000 0,01534235 0,03960428 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01534235 0,03955988 ! localization within membrane GO:0051668 15 9 0,000 0,01534235 0,03951558 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01703295 0,04382078 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01703295 0,04377182 ! neuron fate specification GO:0048665 11 10 0,000 0,01703295 0,04372296 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01703295 0,04367422 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01703295 0,04362559 ! thyroid gland development GO:0030878 19 10 0,000 0,01703295 0,04357706 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,01703295 0,04352864 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,01703295 0,04348033 ! synapsis GO:0007129 13 10 0,000 0,01703295 0,04343212 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01703295 0,04338403 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01703295 0,04333604 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01703295 0,04328815 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01703295 0,04324037 ! sulfate transport GO:0008272 12 10 0,000 0,01703295 0,0431927 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01703295 0,04314513 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01703295 0,04309766 ! androgen metabolic process GO:0008209 13 10 0,000 0,01703295 0,0430503 ! phospholipid efflux GO:0033700 16 10 0,000 0,01703295 0,04300305 ! hippocampus development GO:0021766 19 10 0,000 0,01703295 0,0429559 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01703295 0,04290885 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01703295 0,0428619 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01703295 0,04281506 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01703295 0,04276831 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01703295 0,04272168 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,01703295 0,04267514 ! pathogenesis GO:0009405 13 10 0,000 0,01703295 0,0426287 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01703295 0,04258237 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01703295 0,04253613 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01703295 0,04249 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01703295 0,04244396 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01703295 0,04239803 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,01703295 0,04235219 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01703295 0,04230645 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01703295 0,04226082 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01703295 0,04221528 GO:0005978|glycogen biosynthetic process, ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01703295 0,04216983 ! response to X-ray GO:0010165 16 10 0,000 0,01703295 0,04212449 ! B cell proliferation GO:0042100 14 10 0,000 0,01703295 0,04207924 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01703295 0,04203409 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01703295 0,04198904 ! forebrain cell migration GO:0021885 17 10 0,000 0,01703295 0,04194409 ! lipid digestion GO:0044241 15 10 0,000 0,01703295 0,04189923 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01703295 0,04185446 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01703295 0,04180979 ! UV protection GO:0009650 14 10 0,000 0,01703295 0,04176522 ! entry into host cell GO:0030260 20 10 0,000 0,01703295 0,04172074 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01703295 0,04167636 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01703295 0,04163207 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01703295 0,04158787 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01703295 0,04154377 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01703295 0,04149976 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01703295 0,04145585 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01703295 0,04141203 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01703295 0,0413683 ! regulation of organ growth GO:0046620 11 10 0,000 0,01703295 0,04132466 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01703295 0,04128111 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01703295 0,04123766 ! embryonic axis specification GO:0000578 12 10 0,000 0,01703295 0,0411943 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01703295 0,04115103 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01703295 0,04110785 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01703295 0,04106476 ! cranial nerve development GO:0021545 12 10 0,000 0,01703295 0,04102176 ! fucose catabolic process GO:0019317 16 10 0,000 0,01703295 0,04097885 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01703295 0,04093603 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01703295 0,04089329 ! protein sumoylation GO:0016925 12 10 0,000 0,01703295 0,04085065 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01703295 0,0408081 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01703295 0,04076564 ! zymogen activation GO:0031638 14 10 0,000 0,01703295 0,04072326 ! salivary gland development GO:0007431 22 10 0,000 0,01703295 0,04068097 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01703295 0,04063877 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01703295 0,04059666 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01703295 0,04055463 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01703295 0,0405127 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,01703295 0,04047084 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01703295 0,04042908 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01703295 0,0403874 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01703295 0,0403458 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,01703295 0,0403043 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01703295 0,04026287 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01703295 0,04022154 ! detection of bacterium GO:0016045 10 10 0,000 0,01703295 0,04018028 ! embryonic gut development GO:0048566 11 10 0,000 0,01703295 0,04013912 ! activation of innate immune response GO:0002218 10 10 0,000 0,01703295 0,04009803 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,01703295 0,04005703 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01703295 0,04001611 ! developmental induction GO:0031128 13 10 0,000 0,01703295 0,03997528 GO:0045168|cell-cell signaling involved in cell fate specification, ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01703295 0,03993453 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01703295 0,03989387 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01703295 0,03985328 ! rRNA transcription GO:0009303 17 11 0,000 0,01872073 0,04375781 ! respiratory burst GO:0045730 14 11 0,000 0,01872073 0,04371339 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01872073 0,04366905 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01872073 0,04362481 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01872073 0,04358065 ! virus-host interaction GO:0019048 17 11 0,000 0,01872073 0,04353659 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,01872073 0,04349261 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,01872073 0,04344872 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,01872073 0,04340493 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,01872073 0,04336121 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01872073 0,04331759 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,01872073 0,04327406 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,01872073 0,04323061 ! mating GO:0007618 14 11 0,000 0,01872073 0,04318725 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01872073 0,04314397 ! T cell proliferation GO:0042098 20 11 0,000 0,01872073 0,04310079 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01872073 0,04305769 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,01872073 0,04301467 ! bone resorption GO:0045453 16 11 0,000 0,01872073 0,04297174 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01872073 0,0429289 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01872073 0,04288614 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01872073 0,04284347 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01872073 0,04280088 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01872073 0,04275838 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01872073 0,04271596 ! syncytium formation GO:0006949 15 11 0,000 0,01872073 0,04267362 ! plasma membrane organization GO:0007009 18 11 0,000 0,01872073 0,04263137 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01872073 0,0425892 ! focal adhesion formation GO:0048041 24 11 0,000 0,01872073 0,04254712 ! mitotic spindle organization GO:0007052 15 11 0,000 0,01872073 0,04250512 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,01872073 0,0424632 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01872073 0,04242137 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01872073 0,04237961 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01872073 0,04233794 ! adult heart development GO:0007512 11 11 0,000 0,01872073 0,04229635 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01872073 0,04225484 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01872073 0,04221342 ! temperature homeostasis GO:0001659 16 11 0,000 0,01872073 0,04217207 ! L-glutamate transport GO:0015813 16 11 0,000 0,01872073 0,04213081 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,01872073 0,04208962 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01872073 0,04204852 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01872073 0,0420075 ! stem cell development GO:0048864 29 11 0,000 0,01872073 0,04196656 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01872073 0,04192569 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01872073 0,04188491 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01872073 0,0418442 ! vasoconstriction GO:0042310 15 11 0,000 0,01872073 0,04180358 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01872073 0,04176303 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01872073 0,04172256 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01872073 0,04168217 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,01872073 0,04164186 ! ribosome assembly GO:0042255 13 11 0,000 0,01872073 0,04160163 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01872073 0,04156147 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,01872073 0,04152139 ! chromatin silencing GO:0006342 19 11 0,000 0,01872073 0,04148139 ! nucleosome positioning GO:0016584 13 11 0,000 0,01872073 0,04144147 ! T cell homeostasis GO:0043029 20 11 0,000 0,01872073 0,04140162 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01872073 0,04136185 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,01872073 0,04132216 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01872073 0,04128254 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01872073 0,04124299 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01872073 0,04120353 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01872073 0,04116414 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01872073 0,04112482 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01872073 0,04108558 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,01872073 0,04104641 ! male genitalia development GO:0030539 13 11 0,000 0,01872073 0,04100732 ! cholesterol efflux GO:0033344 19 11 0,000 0,01872073 0,0409683 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,01872073 0,04092936 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01872073 0,04089049 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01872073 0,04085169 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01872073 0,04081297 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01872073 0,04077432 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01872073 0,04073575 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01872073 0,04069725 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01872073 0,04065882 ! lysogeny GO:0030069 18 11 0,000 0,01872073 0,04062046 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,01872073 0,04058217 ! acrosome reaction GO:0007340 13 11 0,000 0,01872073 0,04054396 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01872073 0,04050582 ! lactation GO:0007595 20 12 0,000 0,02040572 0,04411011 ! reproductive cellular process GO:0048610 14 12 0,000 0,02040572 0,04406869 ! tRNA modification GO:0006400 14 12 0,000 0,02040572 0,04402735 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,02040572 0,04398608 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,02040572 0,0439449 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,02040572 0,04390379 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,02040572 0,04386276 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,02040572 0,0438218 ! non-recombinational repair GO:0000726 19 12 0,000 0,02040572 0,04378093 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,02040572 0,04374012 ! peroxisomal transport GO:0043574 21 12 0,000 0,02040572 0,0436994 ! cartilage condensation GO:0001502 18 12 0,000 0,02040572 0,04365875 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,02040572 0,04361817 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,02040572 0,04357767 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,02040572 0,04353725 ! heart looping GO:0001947 15 12 0,000 0,02040572 0,0434969 ! palate development GO:0060021 15 12 0,000 0,02040572 0,04345662 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,02040572 0,04341642 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,02040572 0,0433763 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,02040572 0,04333624 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,02040572 0,04329627 ! arginine metabolic process GO:0006525 13 12 0,000 0,02040572 0,04325636 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,02040572 0,04321653 ! methionine metabolic process GO:0006555 13 12 0,000 0,02040572 0,04317677 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,02040572 0,04313709 ! Golgi organization GO:0007030 18 12 0,000 0,02040572 0,04309748 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,02040572 0,04305794 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,02040572 0,04301847 ! monoamine transport GO:0015844 13 12 0,000 0,02040572 0,04297908 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02040572 0,04293976 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,02040572 0,0429005 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,02040572 0,04286133 ! L-amino acid transport GO:0015807 20 12 0,000 0,02040572 0,04282222 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,02040572 0,04278318 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,02040572 0,04274422 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,02040572 0,04270533 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02040572 0,0426665 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,02040572 0,04262775 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,02040572 0,04258907 ! cerebellum development GO:0021549 13 12 0,000 0,02040572 0,04255046 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,02040572 0,04251191 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,02040572 0,04247344 ! histone acetylation GO:0016573 23 12 0,000 0,02040572 0,04243504 ! histone methylation GO:0016571 15 12 0,000 0,02040572 0,0423967 ! gland morphogenesis GO:0022612 23 12 0,000 0,02040572 0,04235844 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,02040572 0,04232025 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,02040572 0,04228212 ! response to gamma radiation GO:0010332 20 12 0,000 0,02040572 0,04224406 ! regulation of epidermis development GO:0045682 17 12 0,000 0,02040572 0,04220607 ! intestinal absorption GO:0050892 19 12 0,000 0,02040572 0,04216815 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,02040572 0,0421303 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,02040572 0,04209251 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,02040572 0,0420548 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,02040572 0,04201715 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,02040572 0,04197956 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,02040572 0,04194205 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,02040572 0,0419046 ! microspike assembly GO:0030035 23 12 0,000 0,02040572 0,04186722 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,02040572 0,0418299 ! response to cold GO:0009409 14 12 0,000 0,02040572 0,04179266 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,02208791 0,04519767 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,02208791 0,0451575 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02208791 0,04511739 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02208791 0,04507736 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,02208791 0,0450374 ! water transport GO:0006833 17 13 0,000 0,02208791 0,04499751 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02208791 0,04495769 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02208791 0,04491794 ! lipid localization GO:0010876 24 13 0,000 0,02208791 0,04487826 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02208791 0,04483865 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02208791 0,04479911 ! organelle fusion GO:0048284 28 13 0,000 0,02208791 0,04475963 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02208791 0,04472023 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02208791 0,0446809 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,02208791 0,04464164 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02208791 0,04460245 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02208791 0,04456332 ! response to hexose stimulus GO:0009746 19 13 0,000 0,02208791 0,04452426 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,02208791 0,04448528 ! glutamate metabolic process GO:0006536 18 13 0,000 0,02208791 0,04444636 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02208791 0,0444075 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02208791 0,04436872 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02208791 0,04433 ! NAD metabolic process GO:0019674 21 13 0,000 0,02208791 0,04429136 ! exocrine system development GO:0035272 27 13 0,000 0,02208791 0,04425277 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02208791 0,04421426 ! bone mineralization GO:0030282 15 13 0,000 0,02208791 0,04417581 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02208791 0,04413743 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02208791 0,04409912 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02208791 0,04406087 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02208791 0,04402269 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,02208791 0,04398458 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02208791 0,04394653 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,02208791 0,04390854 ! genitalia development GO:0048806 15 13 0,000 0,02208791 0,04387063 ! regulation of cellular pH GO:0030641 20 13 0,000 0,02208791 0,04383277 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,02208791 0,04379499 ! cellular pigmentation GO:0033059 24 13 0,000 0,02208791 0,04375727 ! tissue regeneration GO:0042246 21 13 0,000 0,02208791 0,04371961 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02208791 0,04368202 ! cofactor transport GO:0051181 19 13 0,000 0,02208791 0,04364449 ! NADP metabolic process GO:0006739 18 13 0,000 0,02208791 0,04360703 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02208791 0,04356963 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02208791 0,04353229 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02208791 0,04349502 ! gas transport GO:0015669 18 13 0,000 0,02208791 0,04345781 ! regulation of RNA stability GO:0043487 28 13 0,000 0,02208791 0,04342067 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02208791 0,04338359 ! regulation of axon extension GO:0030516 23 13 0,000 0,02208791 0,04334657 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,02208791 0,04330962 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02208791 0,04327273 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02208791 0,0432359 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02208791 0,04319914 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02208791 0,04316243 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02208791 0,04312579 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,0237673 0,04636539 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,0237673 0,0463261 ! superoxide anion generation GO:0042554 18 14 0,000 0,0237673 0,04628687 ! regulation of S phase GO:0033261 18 14 0,000 0,0237673 0,04624771 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,0237673 0,04620862 ! myotube differentiation GO:0014902 21 14 0,000 0,0237673 0,04616959 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,0237673 0,04613063 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,0237673 0,04609173 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,0237673 0,0460529 ! inositol metabolic process GO:0006020 20 14 0,000 0,0237673 0,04601414 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,0237673 0,04597544 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,0237673 0,0459368 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,0237673 0,04589823 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,0237673 0,04585973 ! gene silencing by RNA GO:0031047 20 14 0,000 0,0237673 0,04582129 ! response to cAMP GO:0051591 19 14 0,000 0,0237673 0,04578291 ! limbic system development GO:0021761 25 14 0,000 0,0237673 0,0457446 ! startle response GO:0001964 21 14 0,000 0,0237673 0,04570635 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,0237673 0,04566817 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,0237673 0,04563005 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,0237673 0,04559199 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,0237673 0,045554 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,0237673 0,04551607 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,0237673 0,0454782 ! glycine metabolic process GO:0006544 22 14 0,000 0,0237673 0,0454404 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,0237673 0,04540265 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,0237673 0,04536498 ! regulation of heart rate GO:0002027 23 14 0,000 0,0237673 0,04532736 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,0237673 0,04528981 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,0237673 0,04525231 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,0237673 0,04521488 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,0237673 0,04517752 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,0237673 0,04514021 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,0237673 0,04510297 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,0237673 0,04506578 ! axon cargo transport GO:0008088 27 14 0,000 0,0237673 0,04502866 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,0237673 0,0449916 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,0237673 0,0449546 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,0237673 0,04491766 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,0237673 0,04488078 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0237673 0,04484397 ! mRNA splice site selection GO:0006376 26 14 0,000 0,0237673 0,04480721 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,0237673 0,04477051 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,0237673 0,04473387 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,0237673 0,0446973 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,0237673 0,04466078 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,0237673 0,04462432 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,0237673 0,04458792 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,0237673 0,04455159 ! muscle maintenance GO:0046716 19 14 0,000 0,0237673 0,04451531 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,0237673 0,04447908 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,0237673 0,04444292 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,0237673 0,04440682 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,0237673 0,04437078 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,0237673 0,04433479 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,0237673 0,04429886 ! cilium assembly GO:0042384 20 14 0,000 0,0237673 0,04426299 ! peptide hormone secretion GO:0030072 23 14 0,000 0,0237673 0,04422718 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,02544391 0,04730881 ! positive regulation of cell size GO:0045793 20 15 0,000 0,02544391 0,04727059 ! metencephalon development GO:0022037 19 15 0,000 0,02544391 0,04723244 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02544391 0,04719435 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,02544391 0,04715632 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,02544391 0,04711835 ! skin development GO:0043588 25 15 0,000 0,02544391 0,04708044 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,02544391 0,0470426 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,02544391 0,04700481 ! lipid phosphorylation GO:0046834 23 15 0,000 0,02544391 0,04696709 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,02544391 0,04692942 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,02544391 0,04689182 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,02544391 0,04685428 ! bile acid metabolic process GO:0008206 22 15 0,000 0,02544391 0,04681679 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,02544391 0,04677937 ! adult walking behavior GO:0007628 25 15 0,000 0,02544391 0,04674201 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02544391 0,0467047 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,02544391 0,04666746 ! myoblast differentiation GO:0045445 27 15 0,000 0,02544391 0,04663027 ! centrosome cycle GO:0007098 16 15 0,000 0,02544391 0,04659315 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,02544391 0,04655608 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,02544391 0,04651907 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,02544391 0,04648212 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,02544391 0,04644523 ! cerebral cortex development GO:0021987 29 15 0,000 0,02544391 0,0464084 ! response to osmotic stress GO:0006970 22 15 0,000 0,02544391 0,04637163 ! vesicle coating GO:0006901 25 15 0,000 0,02544391 0,04633491 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,02544391 0,04629825 ! DNA integration GO:0015074 22 15 0,000 0,02544391 0,04626165 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,02544391 0,04622511 ! peptide secretion GO:0002790 27 15 0,000 0,02544391 0,04618863 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,02544391 0,0461522 ! regulation of vasodilation GO:0042312 24 15 0,000 0,02544391 0,04611583 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,02544391 0,04607952 ! neuron recognition GO:0008038 22 15 0,000 0,02544391 0,04604327 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,02544391 0,04600707 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,02544391 0,04597093 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,02544391 0,04593485 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,02544391 0,04589882 ! biomineral formation GO:0031214 18 15 0,000 0,02544391 0,04586285 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,02544391 0,04582693 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,02544391 0,04579107 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,02544391 0,04575527 ! dopamine metabolic process GO:0042417 30 15 0,000 0,02544391 0,04571953 ! organic cation transport GO:0015695 19 15 0,000 0,02544391 0,04568383 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,02544391 0,0456482 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,02544391 0,04561262 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,02544391 0,0455771 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,02544391 0,04554163 ! defense response to virus GO:0051607 27 15 0,000 0,02544391 0,04550622 ! peptide hormone processing GO:0016486 19 15 0,000 0,02544391 0,04547086 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,02544391 0,04543555 ! protein secretion GO:0009306 27 16 0,000 0,02711773 0,04838696 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,02711773 0,04834945 ! hormone secretion GO:0046879 25 16 0,000 0,02711773 0,048312 ! bone remodeling GO:0046849 24 16 0,000 0,02711773 0,0482746 ! endothelial cell migration GO:0043542 22 16 0,000 0,02711773 0,04823727 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,02711773 0,04819999 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,02711773 0,04816277 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02711773 0,04812561 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,02711773 0,0480885 ! glial cell development GO:0021782 24 16 0,000 0,02711773 0,04805145 ! patterning of blood vessels GO:0001569 24 16 0,000 0,02711773 0,04801446 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,02711773 0,04797753 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,02711773 0,04794065 ! protein polyubiquitination GO:0000209 26 16 0,000 0,02711773 0,04790383 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,02711773 0,04786707 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,02711773 0,04783036 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,02711773 0,04779371 ! fructose metabolic process GO:0006000 20 16 0,000 0,02711773 0,04775711 ! regulation of protein binding GO:0043393 27 16 0,000 0,02711773 0,04772057 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,02711773 0,04768409 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,02711773 0,04764766 ! protein export from nucleus GO:0006611 24 16 0,000 0,02711773 0,04761129 ! negative regulation of immune response GO:0050777 28 16 0,000 0,02711773 0,04757497 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,02711773 0,04753871 ! DNA replication initiation GO:0006270 25 16 0,000 0,02711773 0,0475025 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,02711773 0,04746635 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,02711773 0,04743026 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,02711773 0,04739422 ! oogenesis GO:0048477 23 16 0,000 0,02711773 0,04735823 ! G1 phase GO:0051318 27 16 0,000 0,02711773 0,0473223 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,02711773 0,04728642 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02711773 0,0472506 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,02711773 0,04721483 ! steroid catabolic process GO:0006706 22 16 0,000 0,02711773 0,04717911 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02711773 0,04714345 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,02711773 0,04710785 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,02711773 0,04707229 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,02711773 0,04703679 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,02711773 0,04700135 ! sperm-egg recognition GO:0035036 16 16 0,000 0,02711773 0,04696595 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,02711773 0,04693062 ! nerve development GO:0021675 18 16 0,000 0,02711773 0,04689533 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,02711773 0,0468601 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,02878878 0,04971035 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,02878878 0,04967306 ! negative regulation of defense response GO:0031348 19 17 0,000 0,02878878 0,04963583 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,02878878 0,04959864 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,02878878 0,04956152 ! glycerol metabolic process GO:0006071 20 17 0,000 0,02878878 0,04952445 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,02878878 0,04948744 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,02878878 0,04945048 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02878878 0,04941358 ! signal complex assembly GO:0007172 29 17 0,000 0,02878878 0,04937673 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,02878878 0,04933993 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,02878878 0,04930319 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,02878878 0,04926651 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,02878878 0,04922988 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,02878878 0,04919331 ! memory GO:0007613 25 17 0,000 0,02878878 0,04915679 ! keratinization GO:0031424 17 17 0,000 0,02878878 0,04912032 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,02878878 0,04908391 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,02878878 0,04904755 ! retinoid metabolic process GO:0001523 22 17 0,000 0,02878878 0,04901124 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,02878878 0,04897499 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,02878878 0,0489388 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,02878878 0,04890265 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,02878878 0,04886656 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,02878878 0,04883052 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,02878878 0,04879454 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,02878878 0,04875861 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,02878878 0,04872273 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,02878878 0,0486869 ! membrane budding GO:0006900 29 17 0,000 0,02878878 0,04865113 ! heme metabolic process GO:0042168 27 17 0,000 0,02878878 0,04861541 ! actin filament bundle formation GO:0051017 26 17 0,000 0,02878878 0,04857974 ! neuromuscular junction development GO:0007528 23 17 0,000 0,02878878 0,04854413 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,02878878 0,04850856 ! body fluid secretion GO:0007589 27 17 0,000 0,02878878 0,04847305 ! stem cell differentiation GO:0048863 36 17 0,000 0,02878878 0,04843759 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,02878878 0,04840219 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,02878878 0,04836683 ! sensory perception of pain GO:0019233 23 17 0,000 0,02878878 0,04833153 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,02878878 0,04829627 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,02878878 0,04826107 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,02878878 0,04822592 ! synaptogenesis GO:0007416 24 17 0,000 0,02878878 0,04819082 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,02878878 0,04815578 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02878878 0,04812078 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,02878878 0,04808583 ! cell-cell junction organization GO:0045216 25 17 0,000 0,02878878 0,04805094 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,02878878 0,04801609 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,02878878 0,0479813 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,02878878 0,04794655 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,02878878 0,04791186 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,02878878 0,04787722 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,02878878 0,04784262 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,03045705 0,05057849 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,03045705 0,050542 ! positive regulation of translation GO:0045727 28 18 0,000 0,03045705 0,05050556 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,03045705 0,05046917 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,03045705 0,05043284 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,03045705 0,05039656 ! cAMP metabolic process GO:0046058 33 18 0,000 0,03045705 0,05036032 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,03045705 0,05032415 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,03045705 0,05028802 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,03045705 0,05025195 ! axis specification GO:0009798 26 18 0,000 0,03045705 0,05021592 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,03045705 0,05017995 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,03045705 0,05014403 ! pancreas development GO:0031016 26 18 0,000 0,03045705 0,05010816 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,03045705 0,05007235 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,03045705 0,05003658 ! glutamine metabolic process GO:0006541 23 18 0,000 0,03045705 0,05000086 ! response to retinoic acid GO:0032526 25 18 0,000 0,03045705 0,0499652 ! pigmentation during development GO:0048066 31 18 0,000 0,03045705 0,04992959 ! central nervous system neuron development GO:0021954 30 18 0,000 0,03045705 0,04989403 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,03045705 0,04985851 ! fucose metabolic process GO:0006004 26 18 0,000 0,03045705 0,04982305 ! response to fungus GO:0009620 19 18 0,000 0,03045705 0,04978764 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,03045705 0,04975228 ! heart process GO:0003015 27 18 0,000 0,03045705 0,04971697 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,03045705 0,04968171 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,03045705 0,0496465 ! visual learning GO:0008542 35 18 0,000 0,03045705 0,04961134 ! somitogenesis GO:0001756 24 18 0,000 0,03045705 0,04957623 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,03045705 0,04954117 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,03045705 0,04950616 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,03045705 0,04947119 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,03045705 0,04943628 ! vitamin transport GO:0051180 24 18 0,000 0,03045705 0,04940142 ! hormone transport GO:0009914 27 18 0,000 0,03045705 0,0493666 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,03045705 0,04933184 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,03045705 0,04929712 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,03045705 0,04926246 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,03045705 0,04922784 ! cell-cell recognition GO:0009988 20 18 0,000 0,03045705 0,04919327 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,03045705 0,04915875 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,03045705 0,04912427 ! regulation of glucose import GO:0046324 21 18 0,000 0,03045705 0,04908985 GO:0010827|regulation of glucose transport, ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,03045705 0,04905547 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,03045705 0,04902114 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,03045705 0,04898686 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,03212255 0,05162953 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,03212255 0,05159348 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,03212255 0,05155747 ! positive regulation of ossification GO:0045778 30 19 0,000 0,03212255 0,05152152 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,03212255 0,05148562 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,03212255 0,05144976 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,03212255 0,05141396 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,03212255 0,05137821 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,03212255 0,0513425 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,03212255 0,05130685 ! regeneration GO:0031099 32 19 0,000 0,03212255 0,05127124 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,03212255 0,05123569 ! response to alkaloid GO:0043279 32 19 0,000 0,03212255 0,05120018 ! sensory perception of taste GO:0050909 23 19 0,000 0,03212255 0,05116472 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,03212255 0,05112932 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,03212255 0,05109396 ! smooth muscle contraction GO:0006939 36 19 0,000 0,03212255 0,05105865 ! peroxisome organization GO:0007031 29 19 0,000 0,03212255 0,05102338 ! digestive system process GO:0022600 30 19 0,000 0,03212255 0,05098817 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,03212255 0,05095301 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,03212255 0,05091789 ! response to vitamin A GO:0033189 26 19 0,000 0,03212255 0,05088282 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,03212255 0,05084781 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,03212255 0,05081283 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,03212255 0,05077791 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,03212255 0,05074304 ! sex determination GO:0007530 29 19 0,000 0,03212255 0,05070821 ! plasma membrane fusion GO:0045026 23 19 0,000 0,03212255 0,05067343 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,03212255 0,0506387 ! cytolysis GO:0019835 20 19 0,000 0,03212255 0,05060401 ! renal system process GO:0003014 35 19 0,000 0,03212255 0,05056938 ! vasodilation GO:0042311 33 19 0,000 0,03212255 0,05053479 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,03212255 0,05050025 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,03212255 0,05046575 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,03212255 0,0504313 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,03212255 0,0503969 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,03212255 0,05036255 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,03212255 0,05032824 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,03212255 0,05029398 ! sarcomere organization GO:0045214 23 19 0,000 0,03212255 0,05025977 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,03212255 0,0502256 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,03212255 0,05019148 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,03212255 0,05015741 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,03212255 0,05012338 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,03212255 0,0500894 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,03212255 0,05005546 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,03212255 0,05002157 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,03212255 0,04998773 ! protein stabilization GO:0050821 26 19 0,000 0,03212255 0,04995393 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,03378528 0,05250416 ! iron ion transport GO:0006826 37 20 0,000 0,03378528 0,0524687 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,03378528 0,0524333 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,03378528 0,05239794 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,03378528 0,05236263 ! response to vitamin GO:0033273 29 20 0,000 0,03378528 0,05232737 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,03378528 0,05229216 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,03378528 0,05225699 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,03378528 0,05222187 ! spinal cord development GO:0021510 31 20 0,000 0,03378528 0,0521868 ! response to ethanol GO:0045471 37 20 0,000 0,03378528 0,05215178 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,03378528 0,0521168 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,03378528 0,05208187 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,03378528 0,05204699 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,03378528 0,05201215 ! chromosome condensation GO:0030261 31 20 0,000 0,03378528 0,05197736 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,03378528 0,05194261 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,03378528 0,05190792 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,03378528 0,05187326 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,03378528 0,05183866 ! pallium development GO:0021543 38 20 0,000 0,03378528 0,0518041 ! DNA modification GO:0006304 28 20 0,000 0,03378528 0,05176959 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,03378528 0,05173512 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,03378528 0,0517007 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,03378528 0,05166632 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,03378528 0,05163199 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,03378528 0,05159771 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,03378528 0,05156347 ! collagen catabolic process GO:0030574 25 20 0,000 0,03378528 0,05152928 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,03378528 0,05149513 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,03378528 0,05146103 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,03378528 0,05142697 ! alditol metabolic process GO:0019400 24 20 0,000 0,03378528 0,05139296 ! actin filament-based movement GO:0030048 34 20 0,000 0,03378528 0,05135899 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,03544525 0,05384682 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,03544525 0,05381128 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,03544525 0,05377578 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,03544525 0,05374033 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,03544525 0,05370493 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,03544525 0,05366958 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,03544525 0,05363427 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,03544525 0,053599 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,03544525 0,05356379 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,03544525 0,05352862 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,03544525 0,0534935 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,03544525 0,05345842 ! protein amino acid acylation GO:0043543 37 21 0,000 0,03544525 0,05342339 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,03544525 0,0533884 ! vesicle docking GO:0048278 27 21 0,000 0,03544525 0,05335346 ! phototransduction GO:0007602 25 21 0,000 0,03544525 0,05331857 ! dendrite development GO:0016358 35 21 0,000 0,03544525 0,05328372 ! visual behavior GO:0007632 39 21 0,000 0,03544525 0,05324891 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,03544525 0,05321416 ! ovarian follicle development GO:0001541 30 21 0,000 0,03544525 0,05317944 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,03544525 0,05314478 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,03544525 0,05311015 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,03544525 0,05307558 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,03544525 0,05304105 ! cell aging GO:0007569 32 21 0,000 0,03544525 0,05300656 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,03544525 0,05297212 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,03544525 0,05293772 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,03544525 0,05290337 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,03544525 0,05286906 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,03544525 0,05283479 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,03544525 0,05280057 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,03544525 0,0527664 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,03544525 0,05273227 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,03544525 0,05269818 ! fatty acid transport GO:0015908 30 21 0,000 0,03544525 0,05266414 ! immunoglobulin production GO:0002377 33 21 0,000 0,03544525 0,05263014 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,03544525 0,05259618 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,03544525 0,05256227 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,03544525 0,05252841 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,03544525 0,05249458 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,03544525 0,0524608 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,03544525 0,05242707 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,03544525 0,05239337 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,03544525 0,05235972 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,03544525 0,05232611 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,03544525 0,05229255 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,03544525 0,05225903 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,03544525 0,05222555 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,03544525 0,05219212 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,03710247 0,05459737 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,03710247 0,05456246 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,03710247 0,05452759 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,03710247 0,05449277 ! viral genome replication GO:0019079 29 22 0,000 0,03710247 0,054458 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,03710247 0,05442327 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,03710247 0,05438858 ! leukocyte adhesion GO:0007159 38 22 0,000 0,03710247 0,05435394 ! molting cycle process GO:0022404 40 22 0,000 0,03710247 0,05431934 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,03710247 0,05428479 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,03710247 0,05425027 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,03710247 0,05421581 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,03710247 0,05418139 ! vasculogenesis GO:0001570 33 22 0,000 0,03710247 0,05414701 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,03710247 0,05411267 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,03710247 0,05407838 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,03710247 0,05404413 ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,03710247 0,05400993 ! lysosome organization GO:0007040 37 22 0,000 0,03710247 0,05397576 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,03710247 0,05394165 GO:0051693|actin filament capping, ! coenzyme catabolic process GO:0009109 33 22 0,000 0,03710247 0,05390757 ! regulation of behavior GO:0050795 38 22 0,000 0,03710247 0,05387354 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,03710247 0,05383955 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,03710247 0,0538056 ! membrane depolarization GO:0051899 35 22 0,000 0,03710247 0,0537717 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,03710247 0,05373784 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,03710247 0,05370402 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,03710247 0,05367024 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,03710247 0,05363651 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,03710247 0,05360282 ! blastocyst development GO:0001824 37 22 0,000 0,03710247 0,05356917 ! neural tube closure GO:0001843 33 22 0,000 0,03710247 0,05353556 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,03710247 0,053502 ! protein tetramerization GO:0051262 39 22 0,000 0,03710247 0,05346847 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,03875693 0,05581775 ! neuron fate commitment GO:0048663 32 23 0,000 0,03875693 0,05578282 ! embryonic pattern specification GO:0009880 31 23 0,000 0,03875693 0,05574793 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,03875693 0,05571309 ! myelination GO:0042552 35 23 0,000 0,03875693 0,05567829 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,03875693 0,05564354 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,03875693 0,05560883 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,03875693 0,05557416 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,03875693 0,05553953 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,03875693 0,05550495 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,03875693 0,05547041 ! vesicle targeting GO:0006903 32 23 0,000 0,03875693 0,05543591 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,03875693 0,05540146 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,03875693 0,05536705 ! osteoblast differentiation GO:0001649 40 23 0,000 0,03875693 0,05533268 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,03875693 0,05529835 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,03875693 0,05526407 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,03875693 0,05522983 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,03875693 0,05519563 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,03875693 0,05516148 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,03875693 0,05512736 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,03875693 0,05509329 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,03875693 0,05505926 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,03875693 0,05502528 ! pentose metabolic process GO:0019321 31 23 0,000 0,03875693 0,05499133 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,03875693 0,05495743 ! spermatid development GO:0007286 33 23 0,000 0,03875693 0,05492357 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,03875693 0,05488975 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,03875693 0,05485597 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,03875693 0,05482223 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,03875693 0,05478854 ! telomere organization GO:0032200 32 23 0,000 0,03875693 0,05475488 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,03875693 0,05472127 ! regulation of amine transport GO:0051952 38 23 0,000 0,03875693 0,0546877 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,04040865 0,05698338 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,04040865 0,05694846 ! initiation of viral infection GO:0019059 42 24 0,000 0,04040865 0,05691359 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,04040865 0,05687876 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,04040865 0,05684397 ! superoxide metabolic process GO:0006801 32 24 0,000 0,04040865 0,05680922 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,04040865 0,05677452 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,04040865 0,05673986 ! fat cell differentiation GO:0045444 37 24 0,000 0,04040865 0,05670524 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,04040865 0,05667067 ! sperm motility GO:0030317 27 24 0,000 0,04040865 0,05663613 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,04040865 0,05660164 ! vacuole organization GO:0007033 39 24 0,000 0,04040865 0,05656719 ! receptor metabolic process GO:0043112 37 24 0,000 0,04040865 0,05653278 ! response to toxin GO:0009636 38 24 0,000 0,04040865 0,05649841 ! primary neural tube formation GO:0014020 35 24 0,000 0,04040865 0,05646409 ! negative regulation of cell development GO:0010721 56 24 0,000 0,04040865 0,05642981 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,04040865 0,05639557 ! base-excision repair GO:0006284 31 24 0,000 0,04040865 0,05636137 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,04040865 0,05632721 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,04040865 0,05629309 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,04040865 0,05625901 ! glutathione metabolic process GO:0006749 29 24 0,000 0,04040865 0,05622498 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,04040865 0,05619099 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,04040865 0,05615703 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,04040865 0,05612312 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,04205762 0,05837811 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,04205762 0,0583429 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,04205762 0,05830773 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,04205762 0,05827261 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,04205762 0,05823752 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,04205762 0,05820248 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,04205762 0,05816748 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,04205762 0,05813253 ! peptide transport GO:0015833 43 25 0,000 0,04205762 0,05809761 ! male gonad development GO:0008584 33 25 0,000 0,04205762 0,05806274 ! iron ion homeostasis GO:0055072 39 25 0,000 0,04205762 0,05802791 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,04205762 0,05799312 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,04205762 0,05795837 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,04205762 0,05792367 ! phospholipid transport GO:0015914 35 25 0,000 0,04205762 0,057889 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,04205762 0,05785438 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,04205762 0,0578198 ! detection of light stimulus GO:0009583 30 25 0,000 0,04205762 0,05778526 ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,04205762 0,05775076 ! leukocyte proliferation GO:0070661 39 25 0,000 0,04205762 0,0577163 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,04205762 0,05768189 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,04370385 0,05990397 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,04370385 0,05986829 ! translational initiation GO:0006413 43 26 0,000 0,04370385 0,05983265 ! regulation of pH GO:0006885 36 26 0,000 0,04370385 0,05979706 ! circadian rhythm GO:0007623 42 26 0,000 0,04370385 0,05976151 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,04370385 0,059726 ! post-embryonic development GO:0009791 42 26 0,000 0,04370385 0,05969053 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,04370385 0,05965511 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,04370385 0,05961973 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,04370385 0,05958439 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,04370385 0,05954909 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,04370385 0,05951383 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,04370385 0,05947862 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,04370385 0,05944344 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,04370385 0,05940831 ! regulation of coagulation GO:0050818 39 26 0,000 0,04370385 0,05937322 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,04534735 0,0615696 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,04534735 0,06153328 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,04534735 0,06149699 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,04534735 0,06146076 ! membrane docking GO:0022406 39 27 0,000 0,04534735 0,06142456 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,04534735 0,06138841 ! catechol metabolic process GO:0009712 43 27 0,000 0,04534735 0,0613523 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,04534735 0,06131623 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,04534735 0,0612802 ! myofibril assembly GO:0030239 36 27 0,000 0,04534735 0,06124422 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,04534735 0,06120828 ! response to ionizing radiation GO:0010212 47 27 0,000 0,04534735 0,06117238 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,04534735 0,06113652 ! natural killer cell activation GO:0030101 35 27 0,000 0,04534735 0,0611007 ! lipid oxidation GO:0034440 38 27 0,000 0,04534735 0,06106493 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,04534735 0,0610292 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,04534735 0,06099351 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,04534735 0,06095786 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,04534735 0,06092226 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,04534735 0,06088669 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,04534735 0,06085117 ! gene silencing GO:0016458 41 27 0,000 0,04534735 0,06081569 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,04698812 0,06297941 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,04698812 0,06294273 ! phenol metabolic process GO:0018958 44 28 0,000 0,04698812 0,06290609 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,04698812 0,0628695 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,04698812 0,06283295 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,04698812 0,06279644 ! cell junction assembly GO:0034329 56 28 0,000 0,04698812 0,06275997 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,04698812 0,06272354 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,04698812 0,06268716 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,04698812 0,06265082 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,04698812 0,06261452 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,04698812 0,06257827 ! response to organic cyclic substance GO:0014070 47 28 0,000 0,04698812 0,06254205 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,04698812 0,06250588 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,04698812 0,06246975 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,04698812 0,06243366 ! mesoderm formation GO:0001707 46 28 0,000 0,04698812 0,06239761 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,04698812 0,06236161 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,04698812 0,06232564 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,04698812 0,06228972 ! ensheathment of neurons GO:0007272 43 28 0,000 0,04698812 0,06225384 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,04698812 0,062218 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,04698812 0,0621822 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,04698812 0,06214644 ! neural tube formation GO:0001841 41 28 0,000 0,04698812 0,06211073 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,04698812 0,06207505 ! regulation of B cell activation GO:0050864 42 28 0,000 0,04698812 0,06203942 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,04862616 0,06416532 ! regulation of innate immune response GO:0045088 38 29 0,000 0,04862616 0,06412853 ! ovulation cycle process GO:0022602 41 29 0,000 0,04862616 0,06409178 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,04862616 0,06405507 ! protein targeting to membrane GO:0006612 53 29 0,000 0,04862616 0,06401841 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,04862616 0,06398178 ! mismatch repair GO:0006298 34 29 0,000 0,04862616 0,0639452 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,04862616 0,06390866 ! muscle cell development GO:0055001 38 29 0,000 0,04862616 0,06387216 ! formation of primary germ layer GO:0001704 48 29 0,000 0,04862616 0,06383571 ! telencephalon development GO:0021537 52 29 0,000 0,04862616 0,06379929 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,04862616 0,06376292 ! eye morphogenesis GO:0048592 51 29 0,000 0,04862616 0,06372659 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,04862616 0,0636903 ! tissue homeostasis GO:0001894 42 29 0,000 0,04862616 0,06365405 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,05026147 0,06575733 ! collagen metabolic process GO:0032963 40 30 0,000 0,05026147 0,06571995 ! organic anion transport GO:0015711 51 30 0,000 0,05026147 0,06568261 ! cholesterol transport GO:0030301 46 30 0,000 0,05026147 0,06564531 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,05026147 0,06560805 ! spliceosome assembly GO:0000245 49 30 0,000 0,05026147 0,06557084 ! spindle organization GO:0007051 37 30 0,000 0,05026147 0,06553367 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,05026147 0,06549654 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,05026147 0,06545945 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,05026147 0,06542241 ! ceramide metabolic process GO:0006672 43 30 0,000 0,05026147 0,0653854 ! ovulation cycle GO:0042698 43 30 0,000 0,05026147 0,06534844 ! hindbrain development GO:0030902 45 30 0,000 0,05026147 0,06531152 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,05026147 0,06527464 ! adult locomotory behavior GO:0008344 47 30 0,000 0,05026147 0,06523781 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,05026147 0,06520101 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,05026147 0,06516426 ! response to heat GO:0009408 41 30 0,000 0,05026147 0,06512754 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,05026147 0,06509087 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,05026147 0,06505424 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,05189408 0,06712957 ! negative regulation of secretion GO:0051048 49 31 0,000 0,05189408 0,06709183 ! mammary gland development GO:0030879 57 31 0,000 0,05189408 0,06705414 ! glial cell differentiation GO:0010001 55 31 0,000 0,05189408 0,06701649 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,05189408 0,06697889 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,05189408 0,06694132 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,05189408 0,0669038 ! odontogenesis GO:0042476 50 31 0,000 0,05189408 0,06686632 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,05189408 0,06682888 ! segmentation GO:0035282 41 31 0,000 0,05189408 0,06679148 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,05189408 0,06675412 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,05189408 0,06671681 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,05189408 0,06667954 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,05189408 0,06664231 ! cell fate specification GO:0001708 37 31 0,000 0,05189408 0,06660512 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,05189408 0,06656797 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,05189408 0,06653087 ! RNA modification GO:0009451 40 31 0,000 0,05189408 0,0664938 ! regulation of muscle development GO:0048634 48 32 0,000 0,05352396 0,06854405 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,05352396 0,06850591 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,05352396 0,06846781 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,05352396 0,06842975 ! meiosis I GO:0007127 52 32 0,000 0,05352396 0,06839173 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,05352396 0,06835376 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,05352396 0,06831583 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,05352396 0,06827793 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,05352396 0,06824009 ! peripheral nervous system development GO:0007422 53 32 0,000 0,05352396 0,06820228 ! regulation of protein stability GO:0031647 48 32 0,000 0,05352396 0,06816452 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,05352396 0,06812679 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,05352396 0,06808911 ! cytokine production GO:0001816 44 32 0,000 0,05352396 0,06805147 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,05352396 0,06801388 ! vesicle localization GO:0051648 47 32 0,000 0,05352396 0,06797632 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,05515114 0,07000421 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,05515114 0,0699656 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,05515114 0,06992703 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,05515114 0,0698885 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,05515114 0,06985002 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,05515114 0,06981157 ! sister chromatid segregation GO:0000819 46 33 0,000 0,05515114 0,06977317 ! ear morphogenesis GO:0042471 42 33 0,000 0,05515114 0,06973482 ! actomyosin structure organization GO:0031032 43 33 0,000 0,05515114 0,0696965 ! cell junction organization GO:0034330 63 33 0,000 0,05515114 0,06965823 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,05515114 0,06961999 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,05515114 0,0695818 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,05515114 0,06954366 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,05515114 0,06950555 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,05515114 0,06946749 ! female gonad development GO:0008585 49 33 0,000 0,05515114 0,06942946 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,05515114 0,06939148 ! positive regulation of cell development GO:0010720 54 33 0,000 0,05515114 0,06935354 ! lipid homeostasis GO:0055088 55 33 0,000 0,05515114 0,06931564 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,05515114 0,06927779 ! regulation of proteolysis GO:0030162 50 33 0,000 0,05515114 0,06923997 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,05515114 0,0692022 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,05515114 0,06916447 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,05515114 0,06912677 ! cytokinesis GO:0000910 52 33 0,000 0,05515114 0,06908912 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,05515114 0,06905151 ! mRNA catabolic process GO:0006402 48 34 0,000 0,05677562 0,07104675 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,05677562 0,07100811 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,05677562 0,07096952 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,05677562 0,07093097 ! feeding behavior GO:0007631 45 34 0,000 0,05677562 0,07089247 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,05677562 0,070854 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,05677562 0,07081558 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,05677562 0,07077719 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,05677562 0,07073885 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,05677562 0,07070055 ! neuron migration GO:0001764 46 34 0,000 0,05677562 0,0706623 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,05677562 0,07062408 ! female gamete generation GO:0007292 43 34 0,000 0,05677562 0,0705859 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,05677562 0,07054777 ! polyol metabolic process GO:0019751 44 34 0,000 0,05677562 0,07050968 ! aerobic respiration GO:0009060 47 34 0,000 0,05677562 0,07047163 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,05677562 0,07043361 ! embryonic organ development GO:0048568 45 34 0,000 0,05677562 0,07039565 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,05677562 0,07035772 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,05839739 0,07232849 ! Notch signaling pathway GO:0007219 56 35 0,000 0,05839739 0,07228956 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,05839739 0,07225067 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,05839739 0,07221183 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,05839739 0,07217303 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,05839739 0,07213427 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,05839739 0,07209555 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,05839739 0,07205687 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,05839739 0,07201823 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,05839739 0,07197964 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,05839739 0,07194108 ! glycogen metabolic process GO:0005977 48 35 0,000 0,05839739 0,07190257 ! pigment metabolic process GO:0042440 61 35 0,000 0,05839739 0,0718641 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,05839739 0,07182567 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,06001647 0,0737776 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,06001647 0,07373819 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,06001647 0,07369882 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,06001647 0,07365949 ! negative regulation of binding GO:0051100 58 36 0,000 0,06001647 0,07362021 ! organic ether metabolic process GO:0018904 46 36 0,000 0,06001647 0,07358096 ! tissue remodeling GO:0048771 62 36 0,000 0,06001647 0,07354176 ! neural tube development GO:0021915 50 36 0,000 0,06001647 0,0735026 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,06001647 0,07346348 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,06001647 0,07342441 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,06001647 0,07338537 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,06001647 0,07334638 ! glucan metabolic process GO:0044042 49 36 0,000 0,06001647 0,07330743 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,06163286 0,07524182 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,06163286 0,0752019 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,06163286 0,07516203 ! learning GO:0007612 67 37 0,000 0,06163286 0,07512219 ! ion transmembrane transport GO:0034220 56 37 0,000 0,06163286 0,0750824 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,06163286 0,07504266 ! regulation of protein secretion GO:0050708 51 37 0,000 0,06163286 0,07500295 ! amino acid activation GO:0043038 52 37 0,000 0,06163286 0,07496329 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,06163286 0,07492367 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,06324656 0,07684474 ! gliogenesis GO:0042063 71 38 0,000 0,06324656 0,07680417 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,06324656 0,07676364 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,06324656 0,07672315 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,06324656 0,07668271 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,06324656 0,0766423 ! phagocytosis GO:0006909 60 38 0,000 0,06324656 0,07660194 ! pigmentation GO:0043473 74 38 0,000 0,06324656 0,07656163 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,06485758 0,07847051 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,06485758 0,07842925 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,06485758 0,07838804 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,06485758 0,07834687 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,06485758 0,07830574 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,06485758 0,07826466 ! male sex differentiation GO:0046661 53 39 0,000 0,06485758 0,07822362 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,06485758 0,07818262 ! chromatin remodeling GO:0006338 68 39 0,000 0,06485758 0,07814166 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,06485758 0,07810075 ! JNK cascade GO:0007254 54 39 0,000 0,06485758 0,07805988 ! developmental growth GO:0048589 62 39 0,000 0,06485758 0,07801906 ! cell growth GO:0016049 61 39 0,000 0,06485758 0,07797827 ! synapse organization GO:0050808 55 39 0,000 0,06485758 0,07793753 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,06646592 0,07982852 ! response to calcium ion GO:0051592 58 40 0,000 0,06646592 0,07978686 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,06646592 0,07974524 ! regulation of tube size GO:0035150 60 40 0,000 0,06646592 0,07970366 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,06646592 0,07966212 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,06646592 0,07962063 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,06646592 0,07957919 ! peptide metabolic process GO:0006518 56 40 0,000 0,06646592 0,07953778 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,06646592 0,07949642 ! inner ear development GO:0048839 57 40 0,000 0,06646592 0,0794551 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,06646592 0,07941383 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,06646592 0,07937259 ! double-strand break repair GO:0006302 67 40 0,000 0,06646592 0,0793314 ! B cell differentiation GO:0030183 62 40 0,000 0,06646592 0,07929026 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,06646592 0,07924915 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,06646592 0,07920809 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,06646592 0,07916707 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,06646592 0,0791261 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,06807159 0,08099568 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,06807159 0,0809538 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,06807159 0,08091196 ! glucose transport GO:0015758 52 41 0,000 0,06807159 0,08087017 ! endosome transport GO:0016197 71 41 0,000 0,06807159 0,08082842 ! striated muscle contraction GO:0006941 62 41 0,000 0,06807159 0,08078671 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,06807159 0,08074505 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,06807159 0,08070343 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,06807159 0,08066185 ! biopolymer methylation GO:0043414 62 41 0,000 0,06807159 0,08062031 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,06807159 0,08057882 ! mitochondrial transport GO:0006839 60 42 0,000 0,06967458 0,08243392 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,06967458 0,08239154 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,06967458 0,0823492 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,06967458 0,0823069 ! cellular component disassembly GO:0022411 64 42 0,000 0,06967458 0,08226465 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,06967458 0,08222244 ! hexose transport GO:0008645 54 42 0,000 0,06967458 0,08218028 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,06967458 0,08213815 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,06967458 0,08209607 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,06967458 0,08205404 ! excretion GO:0007588 63 42 0,000 0,06967458 0,08201205 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,06967458 0,0819701 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,06967458 0,08192819 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,06967458 0,08188632 ! positive regulation of binding GO:0051099 59 43 0,000 0,07127491 0,08372436 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 0,000 0,07127491 0,08368162 ! leukocyte migration GO:0050900 60 43 0,000 0,07127491 0,08363893 ! neuromuscular process GO:0050905 79 43 0,000 0,07127491 0,08359628 ! activation of caspase activity GO:0006919 65 43 0,000 0,07127491 0,08355367 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,07127491 0,0835111 ! tRNA processing GO:0008033 49 43 0,000 0,07127491 0,08346858 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,07127491 0,08342611 ! vesicle organization GO:0016050 79 43 0,000 0,07127491 0,08338367 ! methylation GO:0032259 64 43 0,000 0,07127491 0,08334128 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,07287258 0,08516613 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,07287258 0,08512287 ! glycolysis GO:0006096 53 44 0,000 0,07287258 0,08507966 ! regulation of action potential GO:0001508 71 44 0,000 0,07287258 0,0850365 ! regulation of ion transport GO:0043269 57 44 0,000 0,07287258 0,08499338 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,07287258 0,0849503 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,07287258 0,08490726 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,07287258 0,08486427 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,07287258 0,08482132 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,07287258 0,08477842 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,07287258 0,08473556 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,07287258 0,08469274 ! RNA catabolic process GO:0006401 64 45 0,000 0,07446759 0,08650276 ! positive regulation of defense response GO:0031349 59 45 0,000 0,07446759 0,08645909 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,07446759 0,08641547 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,07446759 0,08637189 ! cell recognition GO:0008037 58 45 0,000 0,07446759 0,08632836 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,07446759 0,08628487 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,07605995 0,08808554 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,07605995 0,08804121 ! cell redox homeostasis GO:0045454 63 46 0,000 0,07605995 0,08799693 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,07605995 0,08795269 ! regulation of ossification GO:0030278 71 46 0,000 0,07605995 0,08790849 ! histone modification GO:0016570 68 46 0,000 0,07605995 0,08786434 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,07605995 0,08782023 ! response to UV GO:0009411 75 46 0,000 0,07605995 0,08777616 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,07764966 0,08956581 ! viral infectious cycle GO:0019058 71 47 0,000 0,07764966 0,08952092 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,07764966 0,08947607 ! covalent chromatin modification GO:0016569 75 47 0,000 0,07764966 0,08943126 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,07764966 0,0893865 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,07764966 0,08934178 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,07764966 0,08929711 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,07764966 0,08925249 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,07764966 0,08920791 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,07764966 0,08916337 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,07764966 0,08911888 ! chloride transport GO:0006821 67 48 0,000 0,07923673 0,090895 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,07923673 0,09084969 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,07923673 0,09080442 ! response to temperature stimulus GO:0009266 62 48 0,000 0,07923673 0,0907592 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,07923673 0,09071403 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,07923673 0,0906689 ! gastrulation GO:0007369 73 48 0,000 0,07923673 0,09062381 ! heart morphogenesis GO:0003007 65 48 0,000 0,07923673 0,09057877 ! regulation of DNA replication GO:0006275 75 48 0,000 0,07923673 0,09053377 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,07923673 0,09048882 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,07923673 0,09044391 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,07923673 0,09039905 ! nuclear export GO:0051168 69 48 0,000 0,07923673 0,09035423 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,07923673 0,09030946 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,07923673 0,09026473 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,08082116 0,09202409 ! sensory perception of smell GO:0007608 61 49 0,000 0,08082116 0,09197856 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,08082116 0,09193307 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,08082116 0,09188762 ! RNA elongation GO:0006354 62 49 0,000 0,08082116 0,09184222 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,08082116 0,09179687 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,08082116 0,09175156 ! germ cell development GO:0007281 68 49 0,000 0,08082116 0,0917063 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,08082116 0,09166108 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,08082116 0,0916159 ! cartilage development GO:0051216 70 49 0,000 0,08082116 0,09157077 ! regulation of actin filament length GO:0030832 72 50 0,000 0,08240295 0,09331698 ! ear development GO:0043583 72 50 0,000 0,08240295 0,09327105 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,08240295 0,09322518 ! membrane fusion GO:0006944 80 50 0,000 0,08240295 0,09317934 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,08240295 0,09313355 ! lipid modification GO:0030258 73 50 0,000 0,08240295 0,09308781 ! positive regulation of growth GO:0045927 67 50 0,000 0,08240295 0,09304211 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,08240295 0,09299646 ! proton transport GO:0015992 75 50 0,000 0,08240295 0,09295085 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,08240295 0,09290529 ! positive regulation of secretion GO:0051047 71 51 0,000 0,08398211 0,09463932 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 0,000 0,08398211 0,09459297 ! hydrogen transport GO:0006818 77 51 0,000 0,08398211 0,09454667 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,08398211 0,09450042 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,08398211 0,09445421 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,08398211 0,09440804 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,08398211 0,09436192 ! adult behavior GO:0030534 80 51 0,000 0,08398211 0,09431584 ! transition metal ion transport GO:0000041 74 52 0,000 0,08555864 0,09603947 ! regulation of cellular component size GO:0032535 74 52 0,000 0,08555864 0,09599262 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,08555864 0,09594582 ! aging GO:0007568 79 52 0,000 0,08555864 0,09589906 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,08555864 0,09585235 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,08555864 0,09580568 ! establishment of organelle localization GO:0051656 85 52 0,000 0,08555864 0,09575906 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,08713255 0,09747318 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,08713255 0,0974258 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,08713255 0,09737846 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,08713255 0,09733116 ! single fertilization GO:0007338 59 53 0,000 0,08713255 0,09728392 ! cell projection assembly GO:0030031 76 53 0,000 0,08713255 0,09723671 ! amino acid transport GO:0006865 84 54 0,000 0,08870384 0,09894221 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,08870384 0,09889425 ! glucose catabolic process GO:0006007 66 54 0,000 0,08870384 0,09884633 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,08870384 0,09879847 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,08870384 0,09875065 ! DNA catabolic process GO:0006308 67 54 0,000 0,08870384 0,09870287 ! detection of external stimulus GO:0009581 66 54 0,000 0,08870384 0,09865514 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,08870384 0,09860746 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,08870384 0,09855982 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,08870384 0,09851223 ! exocytosis GO:0006887 74 55 0,000 0,09027252 0,10020598 ! mesoderm development GO:0007498 76 55 0,000 0,09027252 0,10015764 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,09027252 0,10010935 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,09027252 0,1000611 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,09183858 0,10174795 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,09183858 0,10169896 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,09183858 0,10165002 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,09183858 0,10160113 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,09340204 0,1032811 ! carbohydrate transport GO:0008643 74 57 0,000 0,09340204 0,10323147 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,09340204 0,10318189 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,09340204 0,10313236 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,09340204 0,10308287 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,09340204 0,10303343 ! camera-type eye development GO:0043010 88 57 0,000 0,09340204 0,10298403 ! secondary metabolic process GO:0019748 84 57 0,000 0,09340204 0,10293469 ! gonad development GO:0008406 79 57 0,000 0,09340204 0,10288539 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,0949629 0,10455465 ! viral reproductive process GO:0022415 87 58 0,000 0,0949629 0,10450463 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,0949629 0,10445465 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,0949629 0,10440472 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,0949629 0,10435483 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,09652116 0,10601655 ! lung development GO:0030324 94 59 0,000 0,09652116 0,10596595 ! actin filament organization GO:0007015 95 59 0,000 0,09652116 0,10591539 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,09652116 0,10586489 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,09652116 0,10581443 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,09807682 0,10746865 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,09807682 0,10741747 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,09807682 0,10736635 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,09807682 0,10731527 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,09807682 0,10726424 ! regulation of heart contraction GO:0008016 91 60 0,000 0,09807682 0,10721326 ! fertilization GO:0009566 68 60 0,000 0,09807682 0,10716233 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,09807682 0,10711144 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,0996299 0,10875594 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,0996299 0,10870435 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,0996299 0,10865281 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,0996299 0,10860131 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,0996299 0,10854987 ! extracellular matrix organization GO:0030198 103 61 0,000 0,0996299 0,10849847 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,0996299 0,10844712 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,0996299 0,10839582 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,0996299 0,10834457 ! neurotransmitter transport GO:0006836 81 62 0,000 0,10118039 0,10997869 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,10118039 0,10992674 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,10118039 0,10987484 ! respiratory tube development GO:0030323 99 62 0,000 0,10118039 0,10982298 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,10118039 0,10977118 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,10118039 0,10971943 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,1027283 0,11134547 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,1027283 0,11129303 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,1027283 0,11124063 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,1027283 0,11118828 ! viral reproduction GO:0016032 92 63 0,000 0,1027283 0,11113598 ! regulation of lipase activity GO:0060191 109 63 0,000 0,1027283 0,11108373 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,10427363 0,11270177 ! negative regulation of cell size GO:0045792 108 64 0,000 0,10427363 0,11264883 ! appendage morphogenesis GO:0035107 93 64 0,000 0,10427363 0,11259594 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,10427363 0,11254311 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,10427363 0,11249032 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,10427363 0,11243758 ! hexose catabolic process GO:0019320 82 64 0,000 0,10427363 0,11238489 ! respiratory system development GO:0060541 100 64 0,000 0,10427363 0,11233225 ! adaptive immune response GO:0002250 94 64 0,000 0,10427363 0,11227966 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,10581639 0,11388756 ! regulation of caspase activity GO:0043281 97 65 0,000 0,10581639 0,11383429 ! appendage development GO:0048736 94 65 0,000 0,10581639 0,11378107 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,10581639 0,1137279 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,10581639 0,11367478 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,10581639 0,11362171 ! defense response to bacterium GO:0042742 73 65 0,000 0,10581639 0,11356869 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,10581639 0,11351572 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,10581639 0,1134628 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,10735659 0,11506065 ! antigen processing and presentation GO:0019882 96 66 0,000 0,10735659 0,11500705 ! axon guidance GO:0007411 99 66 0,000 0,10735659 0,11495351 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,10735659 0,11490002 ! regulation of immune effector process GO:0002697 101 66 0,000 0,10735659 0,11484658 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,10889421 0,11643733 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,10889421 0,11638322 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,10889421 0,11632916 ! learning or memory GO:0007611 123 68 0,000 0,11042928 0,11791427 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,11042928 0,11785955 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,11042928 0,11780489 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,11042928 0,11775027 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,11042928 0,11769571 ! rhythmic process GO:0048511 105 68 0,000 0,11042928 0,11764119 ! inorganic anion transport GO:0015698 93 68 0,000 0,11042928 0,11758673 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,11196179 0,1191634 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,11196179 0,11910828 ! response to drug GO:0042493 108 69 0,000 0,11196179 0,11905322 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,11196179 0,1189982 ! response to metal ion GO:0010038 103 70 0,000 0,11349174 0,1205686 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,11349174 0,12051293 ! humoral immune response GO:0006959 86 70 0,000 0,11349174 0,12045732 ! eye development GO:0001654 111 70 0,000 0,11349174 0,12040176 ! amine transport GO:0015837 101 70 0,000 0,11349174 0,12034625 ! positive regulation of phosphorylation GO:0042327 102 70 0,000 0,11349174 0,12029079 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,11349174 0,12023538 ! regulation of catabolic process GO:0009894 106 70 0,000 0,11349174 0,12018002 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,11501915 0,1217414 ! muscle cell differentiation GO:0042692 104 71 0,000 0,11501915 0,1216854 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,11501915 0,12162945 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,11501915 0,12157355 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,11501915 0,12151771 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,11501915 0,12146192 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,11501915 0,12140617 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,11654402 0,12295929 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 0,000 0,11654402 0,12290291 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 0,000 0,11654402 0,12284658 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,11654402 0,12279031 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,11654402 0,12273409 ! negative regulation of transport GO:0051051 116 73 0,000 0,11806634 0,12428036 ! regulation of blood pressure GO:0008217 107 73 0,000 0,11806634 0,12422351 ! mitochondrion organization GO:0007005 104 73 0,000 0,11806634 0,12416671 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,11806634 0,12410996 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,11806634 0,12405326 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,11958613 0,12559274 ! response to oxygen levels GO:0070482 137 74 0,000 0,11958613 0,12553542 ! digestion GO:0007586 97 74 0,000 0,11958613 0,12547815 ! protein import into nucleus GO:0006606 118 74 0,000 0,11958613 0,12542093 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,11958613 0,12536377 ! response to inorganic substance GO:0010035 115 75 0,000 0,12110339 0,12689649 ! negative regulation of growth GO:0045926 123 75 0,000 0,12110339 0,12683871 ! response to nutrient GO:0007584 104 75 0,000 0,12110339 0,12678097 ! regulation of ligase activity GO:0051340 114 75 0,000 0,12110339 0,12672329 ! nuclear import GO:0051170 121 75 0,000 0,12110339 0,12666567 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,12110339 0,12660809 ! amine biosynthetic process GO:0009309 97 76 0,000 0,12261812 0,12813343 ! tRNA metabolic process GO:0006399 95 76 0,000 0,12261812 0,12807524 ! response to unfolded protein GO:0006986 99 76 0,000 0,12261812 0,1280171 ! regulation of protein transport GO:0051223 114 76 0,000 0,12261812 0,12795902 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,12413033 0,12947834 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,12413033 0,12941965 ! regulation of DNA binding GO:0051101 119 77 0,000 0,12413033 0,12936101 ! sex differentiation GO:0007548 105 77 0,000 0,12413033 0,12930242 ! protein ubiquitination GO:0016567 125 77 0,000 0,12413033 0,12924389 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,12413033 0,12918541 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,12413033 0,12912698 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,12413033 0,1290686 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,12564001 0,13057932 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,12564001 0,13052034 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,12714718 0,13202642 ! cellular respiration GO:0045333 107 79 0,000 0,12714718 0,13196684 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,12714718 0,13190732 ! T cell activation GO:0042110 134 79 0,000 0,12714718 0,13184785 ! regulation of lyase activity GO:0051339 133 79 0,000 0,12714718 0,13178843 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,12714718 0,13172906 ! chromatin assembly GO:0031497 102 80 0,000 0,12865184 0,13322793 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,12865184 0,13316797 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,12865184 0,13310807 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,12865184 0,13304822 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,12865184 0,13298842 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,13015399 0,13448077 ! mRNA transport GO:0051028 121 81 0,000 0,13015399 0,13442038 ! response to protein stimulus GO:0051789 111 81 0,000 0,13015399 0,13436005 ! regulation of neurological system process GO:0031644 122 81 0,000 0,13015399 0,13429977 ! vitamin metabolic process GO:0006766 103 81 0,000 0,13015399 0,13423955 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,13015399 0,13417937 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,13165364 0,1356646 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,13165364 0,13560384 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,13315079 0,13708452 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of cell adhesion GO:0030155 159 83 0,000 0,13315079 0,13702319 ! regulation of defense response GO:0031347 117 84 0,000 0,13464544 0,13849934 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,13464544 0,13843743 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,13464544 0,13837557 ! sterol metabolic process GO:0016125 120 84 0,000 0,13464544 0,13831377 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,13613761 0,13978415 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,13613761 0,13972177 ! rRNA metabolic process GO:0016072 107 85 0,000 0,13613761 0,13965945 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,13613761 0,13959719 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,13613761 0,13953498 ! regulation of protein localization GO:0032880 132 85 0,000 0,13613761 0,13947283 ! regulation of membrane potential GO:0042391 128 85 0,000 0,13613761 0,13941073 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,13613761 0,13934868 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,13762728 0,14081083 ! cell cycle arrest GO:0007050 150 86 0,000 0,13762728 0,14074822 ! interphase of mitotic cell cycle GO:0051329 156 86 0,000 0,13762728 0,14068567 ! nucleosome organization GO:0034728 114 87 0,000 0,13911447 0,14214273 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,13911447 0,14207961 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,13911447 0,14201655 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,13911447 0,14195354 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,13911447 0,14189059 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,13911447 0,1418277 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,14059918 0,14327786 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,14059918 0,1432144 ! interphase GO:0051325 159 88 0,000 0,14059918 0,14315101 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,14059918 0,14308767 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,14059918 0,14302438 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,14059918 0,14296115 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,14208142 0,14440445 ! reproductive developmental process GO:0003006 127 89 0,000 0,14208142 0,14434067 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,14208142 0,14427694 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,14208142 0,14421327 ! regulation of T cell activation GO:0050863 128 89 0,000 0,14208142 0,14414966 ! leukocyte differentiation GO:0002521 143 90 0,000 0,14356119 0,14558674 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,14356119 0,14552258 ! hormone metabolic process GO:0042445 121 90 0,000 0,14356119 0,14545847 ! RNA localization GO:0006403 135 91 0,000 0,14503848 0,14689058 ! ATP metabolic process GO:0046034 137 91 0,000 0,14503848 0,14682593 ! response to virus GO:0009615 122 91 0,000 0,14503848 0,14676133 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,14651332 0,14818849 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,14651332 0,14812336 ! DNA recombination GO:0006310 146 92 0,000 0,14651332 0,14805827 ! sulfur metabolic process GO:0006790 118 92 0,000 0,14651332 0,14799325 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,14798569 0,14941488 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,14798569 0,14934932 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,14798569 0,14928381 ! electron transport chain GO:0022900 123 94 0,000 0,14945561 0,15070053 ! response to oxidative stress GO:0006979 141 94 0,000 0,14945561 0,15063449 ! regulation of binding GO:0051098 151 95 0,000 0,15092308 0,15204691 ! angiogenesis GO:0001525 149 95 0,000 0,15092308 0,15198034 ! carboxylic acid transport GO:0046942 147 95 0,000 0,15092308 0,15191382 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,1523881 0,15332136 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,1523881 0,15325432 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,1523881 0,15318734 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,1523881 0,15312042 ! protein maturation GO:0051604 129 96 0,000 0,1523881 0,15305355 ! response to light stimulus GO:0009416 153 96 0,000 0,1523881 0,15298675 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,15385068 0,15438768 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,15385068 0,15432035 ! calcium ion transport GO:0006816 167 99 0,000 0,15676852 0,15717855 ! extracellular structure organization GO:0043062 156 99 0,000 0,15676852 0,15711006 ! protein import GO:0017038 156 99 0,000 0,15676852 0,15704163 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,15822379 0,15843043 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,15822379 0,15836149 ! divalent metal ion transport GO:0070838 171 100 0,000 0,15822379 0,15829261 ! protein localization in organelle GO:0033365 161 100 0,000 0,15822379 0,15822379