pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-pos-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/63-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of protein export from nucleus GO:0046825 10 7 3,000 1,687E-08 4,058E-05 ! organ growth GO:0035265 15 7 3,000 1,687E-08 2,029E-05 ! negative regulation of peptide secretion GO:0002792 10 7 3,000 1,687E-08 1,353E-05 GO:0046676|negative regulation of insulin secretion, ! dendrite morphogenesis GO:0048813 13 8 3,000 3,361E-08 2,022E-05 ! regulation of growth hormone secretion GO:0060123 16 8 3,000 3,361E-08 1,617E-05 ! axon extension GO:0048675 15 9 3,000 6,028E-08 2,417E-05 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 3,000 6,028E-08 2,072E-05 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 3,000 1,001E-07 3,01E-05 ! central nervous system neuron axonogenesis GO:0021955 22 10 3,000 1,001E-07 2,676E-05 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 5,000 3,066E-07 7,376E-05 ! cell cycle checkpoint GO:0000075 137 69 5,000 9,665E-07 2,114E-04 ! polyol catabolic process GO:0046174 7 5 2,000 1,041E-06 2,087E-04 GO:0019405|alditol catabolic process, ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 2,000 1,041E-06 1,927E-04 ! negative regulation of hormone secretion GO:0046888 25 17 3,000 1,105E-06 1,9E-04 ! positive regulation of hormone secretion GO:0046887 32 19 3,000 1,787E-06 2,866E-04 ! collagen catabolic process GO:0030574 28 21 3,000 2,739E-06 4,119E-04 ! central nervous system neuron development GO:0021954 46 22 3,000 3,335E-06 4,72E-04 ! central nervous system neuron differentiation GO:0021953 50 24 3,000 4,809E-06 6,428E-04 ! regulation of insulin secretion GO:0050796 37 25 3,000 5,704E-06 7,223E-04 ! telomere organization GO:0032200 43 25 3,000 5,704E-06 6,862E-04 GO:0000723|telomere maintenance, ! regulation of protein localization GO:0032880 176 97 5,000 7,145E-06 8,186E-04 ! multicellular organismal catabolic process GO:0044243 36 27 3,000 7,856E-06 8,591E-04 ! dendrite development GO:0016358 59 28 3,000 9,131E-06 9,552E-04 ! positive regulation of secretion GO:0051047 95 59 4,000 9,163E-06 9,186E-04 ! regulation of peptide secretion GO:0002791 47 29 3,000 1,055E-05 1,016E-03 ! multicellular organism reproduction GO:0032504 111 64 4,000 1,369E-05 1,267E-03 GO:0048609|reproductive process in a multicellular organism, ! collagen metabolic process GO:0032963 45 31 3,000 1,388E-05 1,237E-03 ! triglyceride metabolic process GO:0006641 43 31 3,000 1,388E-05 1,193E-03 ! telomere maintenance via telomerase GO:0007004 21 11 2,000 1,682E-05 1,395E-03 GO:0010833|telomere maintenance via telomere lengthening, ! activation of MAPK activity GO:0000187 115 67 4,000 1,715E-05 1,375E-03 ! DNA damage checkpoint GO:0000077 71 33 3,000 1,792E-05 1,39E-03 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 3,000 2,023E-05 1,521E-03 ! negative regulation of secretion GO:0051048 63 35 3,000 2,276E-05 1,659E-03 ! neutral lipid metabolic process GO:0006638 50 35 3,000 2,276E-05 1,61E-03 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 75 36 3,000 2,551E-05 1,753E-03 ! meiosis I GO:0007127 65 37 3,000 2,849E-05 1,904E-03 ! glycerol ether metabolic process GO:0006662 53 37 3,000 2,849E-05 1,853E-03 ! cellular carbohydrate catabolic process GO:0044275 15 13 2,000 2,895E-05 1,833E-03 ! RNA-dependent DNA replication GO:0006278 23 13 2,000 2,895E-05 1,786E-03 ! carbohydrate homeostasis GO:0033500 53 38 3,000 3,173E-05 1,908E-03 GO:0042593|glucose homeostasis, ! organic ether metabolic process GO:0018904 55 39 3,000 3,522E-05 2,067E-03 ! response to gamma radiation GO:0010332 28 14 2,000 3,672E-05 2,103E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 4,000 3,823E-05 2,139E-03 ! regulation of hormone secretion GO:0046883 62 40 3,000 3,899E-05 2,132E-03 ! multicellular organismal metabolic process GO:0044236 57 40 3,000 3,899E-05 2,085E-03 ! hormone-mediated signaling GO:0009755 74 41 3,000 4,305E-05 2,252E-03 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 4,741E-05 2,427E-03 ! neuron migration GO:0001764 79 42 3,000 4,741E-05 2,376E-03 ! regulation of ligase activity GO:0051340 142 84 4,000 5,138E-05 2,523E-03 ! fructose metabolic process GO:0006000 25 16 2,000 5,61E-05 2,699E-03 ! regulation of protein transport GO:0051223 154 87 4,000 6,08E-05 2,868E-03 GO:0070201|regulation of establishment of protein localization, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 2,000 6,788E-05 3,141E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 6,811E-05 3,092E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 6,811E-05 3,035E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 8,359E-05 3,657E-03 ! estrogen receptor signaling pathway GO:0030520 38 19 2,000 9,606E-05 4,127E-03 ! cellular response to starvation GO:0009267 33 20 2,000 1,126E-04 4,754E-03 ! response to UV GO:0009411 104 53 3,000 1,191E-04 4,941E-03 ! reciprocal meiotic recombination GO:0007131 39 21 2,000 1,309E-04 5,339E-03 ! positive regulation of caspase activity GO:0043280 95 55 3,000 1,377E-04 5,522E-03 GO:0010952|positive regulation of peptidase activity, ! regulation of multicellular organism growth GO:0040014 85 55 3,000 1,377E-04 5,432E-03 ! positive regulation of organelle organization GO:0010638 100 56 3,000 1,478E-04 5,734E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 2,000 1,511E-04 5,77E-03 ! regulation of intracellular transport GO:0032386 101 57 3,000 1,583E-04 5,952E-03 ! regulation of DNA recombination GO:0000018 48 23 2,000 1,731E-04 6,409E-03 ! DNA damage response, signal transduction GO:0042770 128 60 3,000 1,933E-04 7,047E-03 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 1,972E-04 7,081E-03 ! alditol metabolic process GO:0019400 38 24 2,000 1,972E-04 6,977E-03 ! positive regulation of histone modification GO:0031058 5 5 1,000 2,218E-04 7,734E-03 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 1,000 2,218E-04 7,623E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 2,218E-04 7,516E-03 ! regulation of hair follicle development GO:0051797 10 5 1,000 2,218E-04 7,412E-03 GO:0042634|regulation of hair cycle, ! regulation of telomerase activity GO:0051972 6 5 1,000 2,218E-04 7,31E-03 ! somatic stem cell maintenance GO:0035019 15 5 1,000 2,218E-04 7,211E-03 ! neural plate development GO:0001840 8 5 1,000 2,218E-04 7,115E-03 ! stem cell division GO:0017145 11 5 1,000 2,218E-04 7,021E-03 GO:0048103|somatic stem cell division, ! sperm motility GO:0030317 31 25 2,000 2,233E-04 6,977E-03 ! response to starvation GO:0042594 42 25 2,000 2,233E-04 6,888E-03 ! cellular response to nutrient levels GO:0031669 41 25 2,000 2,233E-04 6,801E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 2,515E-04 7,565E-03 GO:0045936|negative regulation of phosphate metabolic process, ! base-excision repair GO:0006284 41 27 2,000 2,82E-04 8,377E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 2,961E-04 8,689E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 3,135E-04 9,088E-03 ! negative regulation of ligase activity GO:0051352 112 68 3,000 3,135E-04 8,979E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 3,000 3,135E-04 8,874E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 3,000 3,316E-04 9,276E-03 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 1,000 3,316E-04 9,172E-03 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 1,000 3,316E-04 9,068E-03 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! response to UV-C GO:0010225 11 6 1,000 3,316E-04 8,966E-03 ! interaction with symbiont GO:0051702 13 6 1,000 3,316E-04 8,866E-03 ! response to exogenous dsRNA GO:0043330 10 6 1,000 3,316E-04 8,769E-03 ! positive regulation of pseudopodium assembly GO:0031274 14 6 1,000 3,316E-04 8,673E-03 GO:0031272|regulation of pseudopodium assembly, ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 3,316E-04 8,58E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 3,316E-04 8,489E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 3,499E-04 8,86E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 3,499E-04 8,768E-03 ! regulation of caspase activity GO:0043281 122 72 3,000 3,903E-04 9,68E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 3,000 3,903E-04 9,581E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 3,000 3,903E-04 9,485E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 3,903E-04 9,39E-03 ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 4,274E-04 0,01018126 GO:0043433|negative regulation of transcription factor activity, ! meiosis GO:0007126 121 74 3,000 4,333E-04 0,0102206 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 3,000 4,333E-04 0,01012138 ! meiotic cell cycle GO:0051321 122 75 3,000 4,56E-04 0,01055005 ! regulation of odontogenesis GO:0042481 13 7 1,000 4,629E-04 0,01060614 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 1,000 4,629E-04 0,01050608 ! spindle checkpoint GO:0031577 15 7 1,000 4,629E-04 0,0104079 ! macrophage differentiation GO:0030225 11 7 1,000 4,629E-04 0,01031153 ! fibrinolysis GO:0042730 10 7 1,000 4,629E-04 0,01021693 ! negative regulation of nuclear division GO:0051784 14 7 1,000 4,629E-04 0,01012404 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 1,000 4,629E-04 0,01003284 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 4,629E-04 9,943E-03 ! response to ionizing radiation GO:0010212 65 32 2,000 4,7E-04 0,01000664 ! hexose biosynthetic process GO:0019319 48 32 2,000 4,7E-04 9,919E-03 ! positive regulation of ligase activity GO:0051351 124 77 3,000 5,04E-04 0,01054522 ! regulation of peptidase activity GO:0052547 134 79 3,000 5,555E-04 0,01152238 ! regulation of microtubule-based process GO:0032886 78 35 2,000 6,137E-04 0,0126208 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 6,152E-04 0,01254435 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 6,152E-04 0,01243894 ! osteoblast development GO:0002076 16 8 1,000 6,152E-04 0,01233528 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 6,152E-04 0,01223334 ! multicellular organismal aging GO:0010259 18 8 1,000 6,152E-04 0,01213306 ! B cell receptor signaling pathway GO:0050853 16 8 1,000 6,152E-04 0,01203442 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 6,396E-04 0,01241072 ! monosaccharide biosynthetic process GO:0046364 52 36 2,000 6,672E-04 0,01284235 ! negative regulation of transport GO:0051051 153 84 3,000 7,005E-04 0,01337545 ! negative regulation of DNA binding GO:0043392 68 37 2,000 7,236E-04 0,01370779 ! autophagic vacuole formation GO:0000045 15 9 1,000 7,885E-04 0,01482211 ! DNA synthesis during DNA repair GO:0000731 14 9 1,000 7,885E-04 0,01470721 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 7,885E-04 0,01459408 GO:0010469|regulation of receptor activity, ! regulation of histone modification GO:0031056 12 9 1,000 7,885E-04 0,01448267 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 7,885E-04 0,01437296 ! regulation of cell division GO:0051302 15 9 1,000 7,885E-04 0,01426489 ! pyrimidine base metabolic process GO:0006206 17 9 1,000 7,885E-04 0,01415843 ! mitochondrion localization GO:0051646 15 9 1,000 7,885E-04 0,01405356 ! regulation of cell cycle process GO:0010564 149 90 3,000 9,075E-04 0,01605401 ! negative regulation of binding GO:0051100 72 40 2,000 9,105E-04 0,01599076 ! polyol metabolic process GO:0019751 66 41 2,000 9,79E-04 0,01706891 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 9,826E-04 0,0170083 ! macroautophagy GO:0016236 17 10 1,000 9,826E-04 0,01688682 ! alpha-beta T cell activation GO:0046631 23 10 1,000 9,826E-04 0,01676705 ! response to dsRNA GO:0043331 20 10 1,000 9,826E-04 0,01664897 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 9,826E-04 0,01653255 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 1,000 9,826E-04 0,01641774 ! establishment of cell polarity GO:0030010 16 10 1,000 9,826E-04 0,01630451 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 3,000 1,026E-03 0,01690152 GO:0010498|proteasomal protein catabolic process, ! alcohol biosynthetic process GO:0046165 59 42 2,000 1,051E-03 0,0171968 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 1,11E-03 0,01804718 ! negative regulation of muscle development GO:0048635 20 11 1,000 1,197E-03 0,01933241 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,197E-03 0,01920353 GO:0010812|negative regulation of cell-substrate adhesion, ! regulation of organ growth GO:0046620 13 11 1,000 1,197E-03 0,01907635 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 1,000 1,197E-03 0,01895085 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 1,000 1,197E-03 0,01882699 ! T cell receptor signaling pathway GO:0050852 23 11 1,000 1,197E-03 0,01870473 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 1,199E-03 0,01861819 ! hormone metabolic process GO:0042445 157 97 3,000 1,199E-03 0,01849884 ! double-strand break repair GO:0006302 81 44 2,000 1,204E-03 0,01844735 ! interphase GO:0051325 213 98 3,000 1,246E-03 0,01897245 ! cell cycle arrest GO:0007050 213 100 3,000 1,343E-03 0,0203166 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,432E-03 0,02153676 ! regulation of cell projection assembly GO:0060491 30 12 1,000 1,432E-03 0,02140299 ! regulation of interleukin-12 production GO:0032655 19 12 1,000 1,432E-03 0,02127087 ! regulation of interleukin-1 secretion GO:0050704 16 12 1,000 1,432E-03 0,02114037 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 1,432E-03 0,02101147 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of calcium-mediated signaling GO:0050850 24 12 1,000 1,432E-03 0,02088413 ! endosome transport GO:0016197 108 47 2,000 1,459E-03 0,02114039 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,55E-03 0,02233729 ! regulation of protein complex disassembly GO:0043244 113 49 2,000 1,646E-03 0,02357075 ! regulation of epidermis development GO:0045682 19 13 1,000 1,687E-03 0,02402213 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 1,687E-03 0,02388082 ! regulation of calcium-mediated signaling GO:0050848 25 13 1,000 1,687E-03 0,02374117 ! regulation of angiogenesis GO:0045765 114 52 2,000 1,954E-03 0,02733111 ! non-recombinational repair GO:0000726 25 14 1,000 1,962E-03 0,02729271 GO:0006303|double-strand break repair via nonhomologous end joining, ! hair follicle morphogenesis GO:0031069 26 14 1,000 1,962E-03 0,02713586 ! palate development GO:0060021 31 14 1,000 1,962E-03 0,0269808 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 1,962E-03 0,0268275 ! bone mineralization GO:0030282 17 14 1,000 1,962E-03 0,02667593 ! stem cell development GO:0048864 43 14 1,000 1,962E-03 0,02652606 GO:0019827|stem cell maintenance, ! negative regulation of cytoskeleton organization GO:0051494 124 54 2,000 2,178E-03 0,02927252 ! embryonic hindlimb morphogenesis GO:0035116 33 15 1,000 2,257E-03 0,03017286 ! cell killing GO:0001906 29 15 1,000 2,257E-03 0,03000616 ! aging GO:0007568 103 55 2,000 2,295E-03 0,03034594 ! positive regulation of cell migration GO:0030335 126 57 2,000 2,543E-03 0,03342829 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 2,572E-03 0,03362884 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 2,572E-03 0,03344707 GO:0031114|regulation of microtubule depolymerization, ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 1,000 2,572E-03 0,03326724 ! positive regulation of cytokine secretion GO:0050715 26 16 1,000 2,572E-03 0,03308934 ! biomineral formation GO:0031214 20 16 1,000 2,572E-03 0,03291334 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 2,572E-03 0,03273919 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of cell cycle process GO:0010948 32 17 1,000 2,906E-03 0,03679452 ! nucleobase metabolic process GO:0009112 37 17 1,000 2,906E-03 0,03660188 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 2,906E-03 0,03641124 ! neural crest cell migration GO:0001755 37 17 1,000 2,906E-03 0,03622258 ! negative regulation of blood coagulation GO:0030195 24 17 1,000 2,906E-03 0,03603587 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 2,906E-03 0,03585107 ! epidermis morphogenesis GO:0048730 40 18 1,000 3,259E-03 0,04000212 ! nerve development GO:0021675 28 18 1,000 3,259E-03 0,03979906 ! regulation of mitosis GO:0007088 105 63 2,000 3,38E-03 0,04107188 GO:0051783|regulation of nuclear division, ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 3,38E-03 0,04086548 ! positive regulation of cell motion GO:0051272 146 64 2,000 3,534E-03 0,04251404 ! skin development GO:0043588 36 19 1,000 3,631E-03 0,04346083 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 3,631E-03 0,04324567 ! cellular response to unfolded protein GO:0034620 33 19 1,000 3,631E-03 0,04303264 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to lipopolysaccharide GO:0032496 30 19 1,000 3,631E-03 0,0428217 ! proximal/distal pattern formation GO:0009954 32 19 1,000 3,631E-03 0,04261281 ! extracellular matrix organization GO:0030198 133 66 2,000 3,855E-03 0,04502215 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 2,000 4,022E-03 0,04674352 ! activation of immune response GO:0002253 105 67 2,000 4,022E-03 0,04651879 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 4,022E-03 0,04629734 ! stem cell differentiation GO:0048863 53 20 1,000 4,022E-03 0,04607688 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 4,022E-03 0,04585851 ! negative regulation of T cell activation GO:0050868 40 20 1,000 4,022E-03 0,04564219 ! negative regulation of coagulation GO:0050819 29 20 1,000 4,022E-03 0,04542791 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 4,193E-03 0,04713867 ! hindlimb morphogenesis GO:0035137 43 21 1,000 4,431E-03 0,04958849 ! axis specification GO:0009798 38 21 1,000 4,431E-03 0,04935892 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 4,431E-03 0,04913146 ! cell aging GO:0007569 44 21 1,000 4,431E-03 0,04890608 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 4,431E-03 0,04868277 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 4,431E-03 0,04846148 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 4,859E-03 0,05290194 ! apoptotic nuclear changes GO:0030262 32 22 1,000 4,859E-03 0,05266364 ! regulation of cytokine secretion GO:0050707 37 22 1,000 4,859E-03 0,05242748 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 4,859E-03 0,05219343 ! myeloid leukocyte differentiation GO:0002573 40 23 1,000 5,306E-03 0,05673385 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 5,306E-03 0,05648281 GO:0010810|regulation of cell-substrate adhesion, ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 1,000 5,306E-03 0,05623399 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to molecule of bacterial origin GO:0002237 34 23 1,000 5,306E-03 0,05598735 ! regulation of transcription factor activity GO:0051090 126 74 2,000 5,312E-03 0,05581425 GO:0090046|regulation of transcription regulator activity, ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 5,515E-03 0,05768829 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 5,77E-03 0,06009719 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 5,77E-03 0,05983815 ! leukocyte homeostasis GO:0001776 44 24 1,000 5,77E-03 0,05958133 ! negative regulation of organelle organization GO:0010639 161 78 2,000 6,149E-03 0,0632271 ! osteoblast differentiation GO:0001649 60 25 1,000 6,252E-03 0,06401235 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 6,252E-03 0,06374111 ! neural crest cell development GO:0014032 54 25 1,000 6,252E-03 0,06347216 GO:0014033|neural crest cell differentiation, ! interaction with host GO:0051701 62 25 1,000 6,252E-03 0,06320547 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 6,252E-03 0,06294102 ! positive regulation of protein secretion GO:0050714 36 25 1,000 6,252E-03 0,06267876 ! regulation of blood coagulation GO:0030193 40 25 1,000 6,252E-03 0,06241868 ! molting cycle process GO:0022404 50 26 1,000 6,752E-03 0,06713241 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! positive regulation of nuclear division GO:0051785 40 26 1,000 6,752E-03 0,06685615 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 6,752E-03 0,06658215 ! response to hypoxia GO:0001666 171 81 2,000 6,826E-03 0,06703164 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 7,27E-03 0,07110344 ! positive regulation of cell projection organization GO:0031346 58 27 1,000 7,27E-03 0,07081557 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 7,27E-03 0,07053003 ! spliceosomal snRNP biogenesis GO:0000387 36 27 1,000 7,27E-03 0,07024677 ! fat cell differentiation GO:0045444 50 27 1,000 7,27E-03 0,06996579 ! autophagy GO:0006914 41 27 1,000 7,27E-03 0,06968704 ! primary neural tube formation GO:0014020 51 27 1,000 7,27E-03 0,0694105 ! regulation of chromosome organization GO:0033044 42 27 1,000 7,27E-03 0,06913615 ! negative regulation of protein polymerization GO:0032272 55 27 1,000 7,27E-03 0,06886396 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 7,27E-03 0,06859391 ! response to oxygen levels GO:0070482 176 83 2,000 7,3E-03 0,06861171 ! negative regulation of growth GO:0045926 155 84 2,000 7,545E-03 0,07063315 ! regulation of actin filament depolymerization GO:0030834 58 28 1,000 7,805E-03 0,07278562 ! negative regulation of protein modification process GO:0031400 60 28 1,000 7,805E-03 0,07250459 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 7,805E-03 0,07222573 ! alcohol catabolic process GO:0046164 130 86 2,000 8,048E-03 0,07419013 ! negative regulation of protein complex assembly GO:0031333 59 29 1,000 8,357E-03 0,07674562 ! immune response-activating signal transduction GO:0002757 47 29 1,000 8,357E-03 0,07645381 GO:0002764|immune response-regulating signal transduction, ! regulation of coagulation GO:0050818 46 29 1,000 8,357E-03 0,07616421 ! positive regulation of protein modification process GO:0031401 136 88 2,000 8,571E-03 0,07781535 ! regulation of DNA binding GO:0051101 155 88 2,000 8,571E-03 0,07752281 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 8,926E-03 0,08043827 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 8,926E-03 0,08013813 ! regulation of B cell activation GO:0050864 50 30 1,000 8,926E-03 0,07984022 ! ossification GO:0001503 188 90 2,000 9,113E-03 0,08120531 ! bone development GO:0060348 189 91 2,000 9,391E-03 0,08337757 ! carbohydrate biosynthetic process GO:0016051 141 93 2,000 9,963E-03 0,08812764 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 9,963E-03 0,08780482 ! spliceosome assembly GO:0000245 67 32 1,000 0,01011542 0,08882376 ! spindle organization GO:0007051 46 32 1,000 0,01011542 0,08850076 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01011542 0,0881801 ! regulation of ARF GTPase activity GO:0032312 65 32 1,000 0,01011542 0,08786176 ! forebrain development GO:0030900 188 95 2,000 0,01055439 0,09134485 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 0,01055439 0,09101745 ! leukocyte differentiation GO:0002521 202 96 2,000 0,01085763 0,09329803 ! positive regulation of immune response GO:0050778 156 96 2,000 0,01085763 0,09296601 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01137053 0,09701237 ! regulation of muscle development GO:0048634 70 35 1,000 0,01202245 0,1022121 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01202245 0,1018522 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,01202245 0,10149482 ! neural tube formation GO:0001841 67 35 1,000 0,01202245 0,10113994 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 0,01269041 0,1063872 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,01269041 0,1060178 ! establishment or maintenance of cell polarity GO:0007163 83 37 1,000 0,01337423 0,11134393 ! regulation of protein stability GO:0031647 73 37 1,000 0,01337423 0,11095999 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01407375 0,11636235 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 1,000 0,01407375 0,11596384 GO:0006956|complement activation, ! nucleus organization GO:0006997 67 38 1,000 0,01407375 0,11556806 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,01407375 0,11517497 ! Rho protein signal transduction GO:0007266 74 39 1,000 0,01478881 0,12061652 ! mesenchymal cell development GO:0014031 87 40 1,000 0,01551924 0,12614629 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! cytokinesis GO:0000910 72 40 1,000 0,01551924 0,12572156 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,0162649 0,13131994 ! T cell differentiation GO:0030217 81 41 1,000 0,0162649 0,13088074 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,0162649 0,13044448 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,0162649 0,1300111 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,01702561 0,1356411 ! regulation of protein secretion GO:0050708 71 42 1,000 0,01702561 0,13519344 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 0,01780122 0,14088728 ! neural tube development GO:0021915 77 43 1,000 0,01780122 0,14042536 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,01780122 0,13996645 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,01859158 0,14570466 ! maintenance of location in cell GO:0051651 97 44 1,000 0,01859158 0,14523159 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 1,000 0,01939652 0,15102921 ! cell growth GO:0016049 84 45 1,000 0,01939652 0,15054202 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,0202159 0,15639694 ! response to calcium ion GO:0051592 81 47 1,000 0,02104956 0,16232447 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,02104956 0,16180586 ! cellular component disassembly GO:0022411 86 48 1,000 0,02189734 0,16778666 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,02189734 0,16725401 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,02189734 0,16672472 ! regulation of ARF protein signal transduction GO:0032012 102 48 1,000 0,02189734 0,16619878 ! activation of caspase activity GO:0006919 84 48 1,000 0,02189734 0,16567614 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,02189734 0,16515678 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,02189734 0,16464066 ! response to temperature stimulus GO:0009266 76 49 1,000 0,02275911 0,17058698 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,02275911 0,17005721 ! ribonucleoprotein complex assembly GO:0022618 95 49 1,000 0,02275911 0,16953072 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,02275911 0,16900747 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02351791 0,1741049 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02351791 0,17357083 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02351791 0,17304004 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02351791 0,17251248 ! neuron fate determination GO:0048664 7 5 0,000 0,02351791 0,17198812 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02351791 0,17146695 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02351791 0,17094892 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02351791 0,17043401 ! polyol transport GO:0015791 12 5 0,000 0,02351791 0,1699222 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02351791 0,16941345 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02351791 0,16890774 ! response to superoxide GO:0000303 10 5 0,000 0,02351791 0,16840504 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02351791 0,16790532 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02351791 0,16740856 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02351791 0,16691473 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02351791 0,1664238 ! female meiosis GO:0007143 7 5 0,000 0,02351791 0,16593575 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02351791 0,16545056 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02351791 0,1649682 ! cobalt ion transport GO:0006824 11 5 0,000 0,02351791 0,16448864 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02351791 0,16401186 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02351791 0,16353784 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02351791 0,16306655 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02351791 0,16259797 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02351791 0,16213207 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02351791 0,16166883 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02351791 0,16120824 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02351791 0,16075026 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02351791 0,16029488 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02351791 0,15984207 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02351791 0,15939181 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02351791 0,15894408 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02351791 0,15849886 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02351791 0,15805612 ! negative chemotaxis GO:0050919 14 5 0,000 0,02351791 0,15761585 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02351791 0,15717803 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02351791 0,15674264 ! behavioral response to pain GO:0048266 9 5 0,000 0,02351791 0,15630965 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02351791 0,15587904 ! Notch receptor processing GO:0007220 8 5 0,000 0,02351791 0,1554508 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02351791 0,15502491 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02351791 0,15460134 ! micturition GO:0060073 9 5 0,000 0,02351791 0,15418009 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02351791 0,15376112 ! copulation GO:0007620 9 5 0,000 0,02351791 0,15334442 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02351791 0,15292998 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02351791 0,15251777 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02351791 0,15210777 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02351791 0,15169998 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02351791 0,15129436 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02351791 0,15089091 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02351791 0,15048961 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02351791 0,15009043 ! grooming behavior GO:0007625 6 5 0,000 0,02351791 0,14969336 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02351791 0,1492984 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02351791 0,1489055 ! response to protozoan GO:0001562 10 5 0,000 0,02351791 0,14851468 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02351791 0,14812589 ! lymph vessel development GO:0001945 10 5 0,000 0,02351791 0,14773914 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02351791 0,14735441 ! endochondral ossification GO:0001958 16 5 0,000 0,02351791 0,14697167 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02351791 0,14659091 ! parathyroid gland development GO:0060017 13 5 0,000 0,02351791 0,14621212 ! anagen GO:0042640 6 5 0,000 0,02351791 0,14583529 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02351791 0,14546039 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02351791 0,14508742 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02351791 0,14471635 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02351791 0,14434717 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02351791 0,14397988 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02351791 0,14361445 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02351791 0,14325087 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02351791 0,14288912 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02351791 0,1425292 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02351791 0,14217109 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02351791 0,14181477 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02351791 0,14146023 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02351791 0,14110746 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02351791 0,14075645 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02351791 0,14040718 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02351791 0,14005963 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02351791 0,13971381 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02351791 0,13936968 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02351791 0,13902725 ! histidine catabolic process GO:0006548 6 5 0,000 0,02351791 0,1386865 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02351791 0,13834741 ! microvillus organization GO:0032528 7 5 0,000 0,02351791 0,13800998 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,02351791 0,13767419 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02351791 0,13734003 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02351791 0,13700749 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02351791 0,13667655 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02351791 0,13634721 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02351791 0,13601945 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02351791 0,13569327 ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02351791 0,13536864 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02351791 0,13504557 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02351791 0,13472403 ! muscle cell migration GO:0014812 8 5 0,000 0,02351791 0,13440402 ! mitochondrial fission GO:0000266 8 5 0,000 0,02351791 0,13408553 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02351791 0,13376854 ! mRNA transcription GO:0009299 9 5 0,000 0,02351791 0,13345305 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02351791 0,13313904 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02351791 0,13282651 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02351791 0,13251544 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02351791 0,13220582 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02351791 0,13189765 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02351791 0,13159091 ! response to food GO:0032094 6 5 0,000 0,02351791 0,1312856 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02351791 0,13098169 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02351791 0,1306792 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02351791 0,13037809 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02351791 0,13007837 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02351791 0,12978003 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,02351791 0,12948305 ! forebrain neuron development GO:0021884 13 5 0,000 0,02351791 0,12918742 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02351791 0,12889315 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02351791 0,12860021 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02351791 0,1283086 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02351791 0,12801831 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02351791 0,12772933 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02351791 0,12744165 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02351791 0,12715526 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02351791 0,12687016 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02351791 0,12658634 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02351791 0,12630378 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02351791 0,12602248 ! basic amino acid transport GO:0015802 11 5 0,000 0,02351791 0,12574243 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02351791 0,12546362 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02351791 0,12518604 ! depyrimidination GO:0045008 10 5 0,000 0,02351791 0,1249097 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02351791 0,12463456 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02351791 0,12436064 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02351791 0,12408792 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02351791 0,12381639 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02351791 0,12354605 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02351791 0,12327689 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02351791 0,1230089 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02351791 0,12274206 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02351791 0,12247639 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02351791 0,12221186 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02351791 0,12194847 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02351791 0,12168622 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02351791 0,12142509 ! response to arsenic GO:0046685 10 5 0,000 0,02351791 0,12116508 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02351791 0,12090618 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02351791 0,12064838 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02351791 0,12039168 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02351791 0,12013608 ! response to cadmium ion GO:0046686 7 5 0,000 0,02351791 0,11988155 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02351791 0,1196281 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02351791 0,11937572 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02351791 0,1191244 ! decidualization GO:0046697 11 5 0,000 0,02351791 0,11887414 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02351791 0,11862493 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02351791 0,11837676 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02351791 0,11812963 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02351791 0,11788352 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02351791 0,11763844 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02351791 0,11739438 ! neural tube patterning GO:0021532 7 5 0,000 0,02351791 0,11715133 ! embryonic cleavage GO:0040016 6 5 0,000 0,02351791 0,11690928 ! peroxisome fission GO:0016559 5 5 0,000 0,02351791 0,11666823 ! histone demethylation GO:0016577 10 5 0,000 0,02351791 0,11642817 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02351791 0,1161891 ! mitotic recombination GO:0006312 9 5 0,000 0,02351791 0,11595101 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02351791 0,11571389 ! metaphase plate congression GO:0051310 7 5 0,000 0,02351791 0,11547774 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02351791 0,11524255 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02351791 0,11500832 ! enteric nervous system development GO:0048484 8 5 0,000 0,02351791 0,11477503 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02351791 0,1145427 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02351791 0,1143113 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02351791 0,11408083 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02351791 0,11385129 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02351791 0,11362267 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02351791 0,11339497 ! plasminogen activation GO:0031639 5 5 0,000 0,02351791 0,11316818 ! B cell homeostasis GO:0001782 13 5 0,000 0,02351791 0,1129423 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02351791 0,11271731 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02351791 0,11249322 ! metaphase GO:0051323 8 5 0,000 0,02351791 0,11227002 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02351791 0,11204771 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02351791 0,11182627 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02351791 0,1116057 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02351791 0,11138601 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02351791 0,11116717 GO:0015991|ATP hydrolysis coupled proton transport, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02351791 0,1109492 ! response to redox state GO:0051775 5 5 0,000 0,02351791 0,11073208 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02351791 0,1105158 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02351791 0,11030037 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02351791 0,11008578 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02351791 0,10987202 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02351791 0,10965909 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02351791 0,10944699 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02351791 0,1092357 ! striatum development GO:0021756 9 5 0,000 0,02351791 0,10902523 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02351791 0,10881556 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02351791 0,1086067 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02351791 0,10839864 ! glial cell migration GO:0008347 11 5 0,000 0,02351791 0,10819138 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02351791 0,10798491 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02351791 0,10777922 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02351791 0,10757432 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02351791 0,10737019 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02351791 0,10716684 ! neuroprotection GO:0043526 6 5 0,000 0,02351791 0,10696426 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02351791 0,10676244 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02351791 0,10656138 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02351791 0,10636107 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02351791 0,10616152 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02351791 0,10596272 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02351791 0,10576466 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02351791 0,10556734 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02351791 0,10537075 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02351791 0,10517489 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02351791 0,10497976 ! spindle assembly GO:0051225 6 5 0,000 0,02351791 0,10478536 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02351791 0,10459167 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02351791 0,10439869 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02351791 0,10420643 ! drug metabolic process GO:0017144 6 5 0,000 0,02351791 0,10401487 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02351791 0,10382402 ! organ regeneration GO:0031100 7 5 0,000 0,02351791 0,10363387 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02351791 0,10344441 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02351791 0,10325564 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02351791 0,10306756 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,02363471 0,10339109 ! regulation of ossification GO:0030278 117 50 1,000 0,02363471 0,10320345 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,02363471 0,10301649 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,02452398 0,10669927 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,02452398 0,10650667 ! chromatin remodeling GO:0006338 109 51 1,000 0,02452398 0,10631476 ! vesicle organization GO:0016050 107 51 1,000 0,02452398 0,10612355 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,02452398 0,10593302 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,02452398 0,10574318 ! cartilage development GO:0051216 90 52 1,000 0,02542678 0,10943979 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,02634298 0,11318071 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,02634298 0,11297896 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02815516 0,12053616 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02815516 0,12032206 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02815516 0,12010872 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02815516 0,11989614 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02815516 0,11968431 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02815516 0,11947323 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02815516 0,11926289 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02815516 0,11905329 ! sleep GO:0030431 13 6 0,000 0,02815516 0,11884442 ! response to oxygen radical GO:0000305 11 6 0,000 0,02815516 0,11863629 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02815516 0,11842888 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02815516 0,1182222 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02815516 0,11801624 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02815516 0,11781099 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02815516 0,11760646 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02815516 0,11740264 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02815516 0,11719952 ! forebrain regionalization GO:0021871 8 6 0,000 0,02815516 0,1169971 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02815516 0,11679538 ! male meiosis GO:0007140 7 6 0,000 0,02815516 0,11659436 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02815516 0,11639402 ! response to zinc ion GO:0010043 9 6 0,000 0,02815516 0,11619438 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02815516 0,11599541 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02815516 0,11579713 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02815516 0,11559952 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02815516 0,11540259 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02815516 0,11520633 ! malate metabolic process GO:0006108 11 6 0,000 0,02815516 0,11501073 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02815516 0,1148158 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02815516 0,11462152 ! protein refolding GO:0042026 15 6 0,000 0,02815516 0,11442791 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02815516 0,11423494 ! opsonization GO:0008228 8 6 0,000 0,02815516 0,11404263 ! mating behavior GO:0007617 7 6 0,000 0,02815516 0,11385096 ! neuron remodeling GO:0016322 15 6 0,000 0,02815516 0,11365993 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02815516 0,11346955 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02815516 0,1132798 ! equilibrioception GO:0050957 14 6 0,000 0,02815516 0,11309069 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02815516 0,1129022 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02815516 0,11271434 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02815516 0,11252711 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02815516 0,1123405 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02815516 0,1121545 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02815516 0,11196913 ! toxin metabolic process GO:0009404 11 6 0,000 0,02815516 0,11178436 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02815516 0,1116002 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02815516 0,11141665 ! nuclear migration GO:0007097 12 6 0,000 0,02815516 0,1112337 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02815516 0,11105135 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02815516 0,11086959 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02815516 0,11068843 ! thymic T cell selection GO:0045061 12 6 0,000 0,02815516 0,11050786 ! protein lipoylation GO:0009249 10 6 0,000 0,02815516 0,11032788 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02815516 0,11014849 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02815516 0,10996968 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02815516 0,10979144 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02815516 0,10961379 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02815516 0,10943671 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02815516 0,10926019 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02815516 0,10908425 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02815516 0,10890888 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02815516 0,10873406 ! hyperosmotic response GO:0006972 9 6 0,000 0,02815516 0,10855981 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02815516 0,10838611 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02815516 0,10821297 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02815516 0,10804038 ! urea metabolic process GO:0019627 7 6 0,000 0,02815516 0,10786835 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02815516 0,10769685 ! neutrophil activation GO:0042119 8 6 0,000 0,02815516 0,10752591 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02815516 0,1073555 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02815516 0,10718563 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02815516 0,1070163 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02815516 0,10684751 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02815516 0,10667925 ! neuron apoptosis GO:0051402 9 6 0,000 0,02815516 0,10651151 ! nucleoside salvage GO:0043174 9 6 0,000 0,02815516 0,1063443 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02815516 0,10617762 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02815516 0,10601146 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02815516 0,10584581 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02815516 0,10568069 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,02815516 0,10551608 ! carnitine transport GO:0015879 10 6 0,000 0,02815516 0,10535198 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02815516 0,10518839 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02815516 0,1050253 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02815516 0,10486273 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02815516 0,10470065 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02815516 0,10453908 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02815516 0,104378 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02815516 0,10421742 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02815516 0,10405733 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02815516 0,10389773 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02815516 0,10373862 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02815516 0,10358 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02815516 0,10342186 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02815516 0,10326421 ! neural nucleus development GO:0048857 14 6 0,000 0,02815516 0,10310703 ! astrocyte development GO:0014002 15 6 0,000 0,02815516 0,10295034 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02815516 0,10279411 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02815516 0,10263836 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02815516 0,10248309 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02815516 0,10232828 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02815516 0,10217394 ! response to copper ion GO:0046688 10 6 0,000 0,02815516 0,10202006 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02815516 0,10186665 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02815516 0,10171369 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02815516 0,1015612 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02815516 0,10140916 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02815516 0,10125758 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02815516 0,10110645 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02815516 0,10095577 ! hair follicle maturation GO:0048820 7 6 0,000 0,02815516 0,10080554 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02815516 0,10065575 ! Schwann cell development GO:0014044 15 6 0,000 0,02815516 0,10050641 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02815516 0,10035751 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02815516 0,10020905 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02815516 0,10006104 ! subpallium development GO:0021544 10 6 0,000 0,02815516 0,09991345 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02815516 0,0997663 ! histone ubiquitination GO:0016574 8 6 0,000 0,02815516 0,09961959 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02815516 0,09947331 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02815516 0,09932745 ! G2 phase GO:0051319 16 6 0,000 0,02815516 0,09918202 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02815516 0,09903702 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02815516 0,09889244 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02815516 0,09874828 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02815516 0,09860454 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02815516 0,09846122 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02815516 0,09831832 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02815516 0,09817583 ! receptor internalization GO:0031623 10 6 0,000 0,02815516 0,09803375 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02815516 0,09789208 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02815516 0,09775082 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02815516 0,09760997 ! protein deubiquitination GO:0016579 14 6 0,000 0,02815516 0,09746953 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,02815516 0,09732948 ! protein destabilization GO:0031648 9 6 0,000 0,02815516 0,09718984 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02815516 0,0970506 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02815516 0,09691176 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02815516 0,09677332 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02815516 0,09663526 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02815516 0,09649761 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02815516 0,09636034 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02815516 0,09622347 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02815516 0,09608698 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02815516 0,09595088 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02815516 0,09581516 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02815516 0,09567983 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02815516 0,09554488 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02815516 0,09541031 ! catecholamine transport GO:0051937 9 6 0,000 0,02815516 0,09527612 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02815516 0,0951423 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02815516 0,09500886 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02815516 0,0948758 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02815516 0,09474311 ! maternal placenta development GO:0001893 12 6 0,000 0,02815516 0,09461078 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02815516 0,09447883 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02815516 0,09434724 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02815516 0,09421602 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02815516 0,09408517 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02815516 0,09395468 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02815516 0,09382454 ! regulation of actin filament length GO:0030832 105 56 1,000 0,02917041 0,0970733 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,02917041 0,09693922 ! regulation of DNA replication GO:0006275 101 56 1,000 0,02917041 0,09680551 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,03013869 0,09988112 ! maintenance of location GO:0051235 118 57 1,000 0,03013869 0,09974373 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,03111965 0,10284872 ! regulation of cellular component size GO:0032535 109 59 1,000 0,03211313 0,10598653 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,03211313 0,10584135 ! DNA catabolic process GO:0006308 86 59 1,000 0,03211313 0,10569656 ! tRNA transcription GO:0009304 14 7 0,000 0,03277055 0,10771302 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03277055 0,10756608 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03277055 0,10741953 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03277055 0,10727338 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03277055 0,10712763 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03277055 0,10698227 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03277055 0,10683731 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03277055 0,10669274 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03277055 0,10654856 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03277055 0,10640477 ! prostate gland development GO:0030850 13 7 0,000 0,03277055 0,10626137 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03277055 0,10611835 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03277055 0,10597572 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03277055 0,10583347 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03277055 0,1056916 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03277055 0,10555011 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03277055 0,105409 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03277055 0,10526827 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03277055 0,10512791 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03277055 0,10498793 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03277055 0,10484832 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03277055 0,10470907 ! glycolipid transport GO:0046836 10 7 0,000 0,03277055 0,1045702 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03277055 0,1044317 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03277055 0,10429356 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,03277055 0,10415579 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03277055 0,10401838 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03277055 0,10388134 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03277055 0,10374465 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03277055 0,10360832 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03277055 0,10347235 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03277055 0,10333674 ! mRNA stabilization GO:0048255 18 7 0,000 0,03277055 0,10320148 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03277055 0,10306658 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03277055 0,10293203 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03277055 0,10279783 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03277055 0,10266398 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03277055 0,10253047 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03277055 0,10239732 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03277055 0,1022645 ! lipoprotein transport GO:0042953 14 7 0,000 0,03277055 0,10213204 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03277055 0,10199991 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03277055 0,10186813 ! rhythmic behavior GO:0007622 15 7 0,000 0,03277055 0,10173669 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03277055 0,10160558 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03277055 0,10147482 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03277055 0,10134439 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03277055 0,10121429 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03277055 0,10108453 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03277055 0,1009551 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03277055 0,100826 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03277055 0,10069723 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03277055 0,10056879 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03277055 0,10044068 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03277055 0,10031289 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03277055 0,10018543 ! spinal cord patterning GO:0021511 13 7 0,000 0,03277055 0,10005829 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03277055 0,09993147 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03277055 0,09980498 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03277055 0,0996788 ! adrenal gland development GO:0030325 17 7 0,000 0,03277055 0,09955295 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03277055 0,09942741 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03277055 0,09930218 ! ovulation GO:0030728 9 7 0,000 0,03277055 0,09917727 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03277055 0,09905268 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03277055 0,0989284 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! microtubule nucleation GO:0007020 20 7 0,000 0,03277055 0,09880443 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03277055 0,09868077 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03277055 0,09855742 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03277055 0,09843437 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03277055 0,09831164 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03277055 0,09818921 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03277055 0,09806708 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03277055 0,09794526 ! galactose metabolic process GO:0006012 13 7 0,000 0,03277055 0,09782374 ! vesicle fusion GO:0006906 17 7 0,000 0,03277055 0,09770252 ! response to dietary excess GO:0002021 8 7 0,000 0,03277055 0,0975816 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03277055 0,09746098 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03277055 0,09734066 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03277055 0,09722063 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03277055 0,0971009 ! purine salvage GO:0043101 10 7 0,000 0,03277055 0,09698147 ! nucleoside transport GO:0015858 8 7 0,000 0,03277055 0,09686233 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03277055 0,09674348 ! parturition GO:0007567 14 7 0,000 0,03277055 0,09662492 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03277055 0,09650665 ! rRNA modification GO:0000154 14 7 0,000 0,03277055 0,09638867 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03277055 0,09627098 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03277055 0,09615358 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03277055 0,09603646 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03277055 0,09591963 ! centrosome duplication GO:0051298 13 7 0,000 0,03277055 0,09580308 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03277055 0,09568681 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03277055 0,09557083 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03277055 0,09545513 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03277055 0,0953397 ! eating behavior GO:0042755 7 7 0,000 0,03277055 0,09522456 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03277055 0,09510969 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03277055 0,0949951 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03277055 0,09488079 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03277055 0,09476675 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03277055 0,09465298 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03277055 0,09453949 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03277055 0,09442627 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03277055 0,09431332 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03277055 0,09420064 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03277055 0,09408823 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03277055 0,09397608 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03277055 0,09386421 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03277055 0,0937526 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03277055 0,09364125 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03277055 0,09353017 ! regulation of meiosis GO:0040020 12 7 0,000 0,03277055 0,09341935 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03277055 0,0933088 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03277055 0,0931985 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03277055 0,09308847 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03277055 0,09297869 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03277055 0,09286918 ! transcription termination GO:0006353 13 7 0,000 0,03277055 0,09275992 ! response to tumor cell GO:0002347 13 7 0,000 0,03277055 0,09265092 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03277055 0,09254218 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03277055 0,09243369 ! anaphase GO:0051322 17 7 0,000 0,03277055 0,09232545 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03277055 0,09221747 ! axonal fasciculation GO:0007413 18 7 0,000 0,03277055 0,09210974 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03277055 0,09200226 ! diuresis GO:0030146 12 7 0,000 0,03277055 0,09189503 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03277055 0,09178805 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03277055 0,09168132 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03277055 0,09157484 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03277055 0,0914686 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03277055 0,09136261 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03277055 0,09125687 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03277055 0,09115137 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03277055 0,09104611 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03277055 0,0909411 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03277055 0,09083633 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03277055 0,0907318 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03277055 0,09062751 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03277055 0,09052346 ! lymph node development GO:0048535 10 7 0,000 0,03277055 0,09041965 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03277055 0,09031607 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03277055 0,09021274 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03277055 0,09010964 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03277055 0,09000677 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03277055 0,08990414 ! adult feeding behavior GO:0008343 9 7 0,000 0,03277055 0,08980175 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03277055 0,08969958 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03277055 0,08959765 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03277055 0,08949595 ! muscle adaptation GO:0043500 14 7 0,000 0,03277055 0,08939448 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03277055 0,08929324 ! retina homeostasis GO:0001895 12 7 0,000 0,03277055 0,08919223 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03277055 0,08909145 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03277055 0,0889909 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03277055 0,08889057 ! protein prenylation GO:0018342 18 7 0,000 0,03277055 0,08879047 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03277055 0,08869059 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03277055 0,08859094 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 0,033119 0,08943244 ! regulation of protein complex assembly GO:0043254 117 61 1,000 0,03413712 0,09207836 ! detection of external stimulus GO:0009581 91 63 1,000 0,03620956 0,09755901 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03736416 0,10055724 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03736416 0,10044489 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03736416 0,10033279 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03736416 0,10022093 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03736416 0,10010933 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03736416 0,09999797 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03736416 0,09988686 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03736416 0,099776 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03736416 0,09966538 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03736416 0,09955501 ! meiotic prophase I GO:0007128 13 8 0,000 0,03736416 0,09944489 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03736416 0,099335 ! oligopeptide transport GO:0006857 15 8 0,000 0,03736416 0,09922536 ! UTP metabolic process GO:0046051 8 8 0,000 0,03736416 0,09911596 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03736416 0,0990068 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03736416 0,09889788 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03736416 0,0987892 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03736416 0,09868076 ! succinate metabolic process GO:0006105 14 8 0,000 0,03736416 0,09857256 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03736416 0,0984646 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03736416 0,09835687 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03736416 0,09824937 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03736416 0,09814211 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03736416 0,09803509 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03736416 0,0979283 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03736416 0,09782174 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03736416 0,09771541 ! reflex GO:0060004 16 8 0,000 0,03736416 0,09760931 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03736416 0,09750344 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03736416 0,09739781 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03736416 0,0972924 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03736416 0,09718722 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03736416 0,09708226 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,03736416 0,09697754 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03736416 0,09687303 ! pigment granule organization GO:0048753 16 8 0,000 0,03736416 0,09676876 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03736416 0,09666471 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03736416 0,09656088 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03736416 0,09645727 ! histidine metabolic process GO:0006547 16 8 0,000 0,03736416 0,09635389 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03736416 0,09625072 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03736416 0,09614778 ! glycine catabolic process GO:0006546 13 8 0,000 0,03736416 0,09604506 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03736416 0,09594256 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03736416 0,09584027 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,03736416 0,09573821 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03736416 0,09563636 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03736416 0,09553472 ! melanin metabolic process GO:0006582 15 8 0,000 0,03736416 0,09543331 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03736416 0,09533211 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03736416 0,09523112 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03736416 0,09513035 ! macrophage activation GO:0042116 12 8 0,000 0,03736416 0,09502978 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03736416 0,09492944 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,03736416 0,0948293 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03736416 0,09472937 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03736416 0,09462966 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03736416 0,09453015 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03736416 0,09443086 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03736416 0,09433177 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03736416 0,09423289 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03736416 0,09413422 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03736416 0,09403575 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03736416 0,09393749 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03736416 0,09383943 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03736416 0,09374158 ! response to UV-B GO:0010224 16 8 0,000 0,03736416 0,09364393 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03736416 0,09354649 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03736416 0,09344925 ! intermediate filament organization GO:0045109 12 8 0,000 0,03736416 0,09335221 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03736416 0,09325537 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,03736416 0,09315873 ! cellular extravasation GO:0045123 12 8 0,000 0,03736416 0,09306229 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03736416 0,09296606 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03736416 0,09287002 ! response to antibiotic GO:0046677 11 8 0,000 0,03736416 0,09277418 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03736416 0,09267853 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03736416 0,09258309 ! DNA topological change GO:0006265 12 8 0,000 0,03736416 0,09248784 ! response to tropane GO:0014073 15 8 0,000 0,03736416 0,09239278 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03736416 0,09229792 ! melanosome transport GO:0032402 13 8 0,000 0,03736416 0,09220326 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,03736416 0,09210879 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03736416 0,09201451 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03736416 0,09192043 ! mast cell activation GO:0045576 14 8 0,000 0,03736416 0,09182653 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03736416 0,09173283 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03736416 0,09163932 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03736416 0,091546 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03736416 0,09145288 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,03736416 0,09135994 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03736416 0,09126718 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03736416 0,09117462 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03736416 0,09108225 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03736416 0,09099006 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03736416 0,09089805 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03736416 0,09080624 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03736416 0,09071461 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03736416 0,09062316 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03736416 0,0905319 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03736416 0,09044082 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03736416 0,09034993 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03736416 0,09025921 ! hormone catabolic process GO:0042447 17 8 0,000 0,03736416 0,09016868 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03736416 0,09007833 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03736416 0,08998816 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03736416 0,08989818 ! ATP catabolic process GO:0006200 11 8 0,000 0,03736416 0,08980837 ! blastocyst growth GO:0001832 19 8 0,000 0,03736416 0,08971874 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03736416 0,08962929 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03736416 0,08954002 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03736416 0,08945092 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03736416 0,089362 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03736416 0,08927326 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03736416 0,0891847 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03736416 0,08909631 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03736416 0,0890081 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03736416 0,08892006 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03736416 0,08883219 GO:0006043|glucosamine catabolic process, ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03736416 0,0887445 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03736416 0,08865698 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03736416 0,08856963 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03736416 0,08848246 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03736416 0,08839545 ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,03832936 0,09058983 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,03832936 0,09050093 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 1,000 0,03832936 0,09041221 ! actin filament organization GO:0007015 148 66 1,000 0,03940669 0,0928624 ! developmental maturation GO:0021700 116 66 1,000 0,03940669 0,09277153 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,04049547 0,09524154 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,04049547 0,09514853 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,04049547 0,0950557 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,04159555 0,09754278 ! regulation of developmental growth GO:0048638 15 9 0,000 0,04193612 0,09824566 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,04193612 0,09815009 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04193612 0,09805471 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04193612 0,09795951 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04193612 0,0978645 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04193612 0,09776967 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04193612 0,09767502 ! phosphate transport GO:0006817 19 9 0,000 0,04193612 0,09758056 ! reproductive behavior GO:0019098 19 9 0,000 0,04193612 0,09748627 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04193612 0,09739218 ! CTP metabolic process GO:0046036 9 9 0,000 0,04193612 0,09729826 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04193612 0,09720452 ! GTP metabolic process GO:0046039 9 9 0,000 0,04193612 0,09711097 ! RNA methylation GO:0001510 15 9 0,000 0,04193612 0,09701759 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04193612 0,09692439 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,04193612 0,09683138 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04193612 0,09673854 ! artery development GO:0060840 24 9 0,000 0,04193612 0,09664588 GO:0048844|artery morphogenesis, ! regulation of glycolysis GO:0006110 21 9 0,000 0,04193612 0,09655339 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04193612 0,09646108 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04193612 0,09636895 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04193612 0,096277 ! chemosensory behavior GO:0007635 20 9 0,000 0,04193612 0,09618522 ! microtubule bundle formation GO:0001578 21 9 0,000 0,04193612 0,09609361 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,04193612 0,09600218 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04193612 0,09591093 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04193612 0,09581984 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04193612 0,09572893 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04193612 0,09563819 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04193612 0,09554763 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04193612 0,09545723 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04193612 0,09536701 ! protein targeting to ER GO:0045047 22 9 0,000 0,04193612 0,09527695 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04193612 0,09518707 ! T cell selection GO:0045058 23 9 0,000 0,04193612 0,09509736 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,04193612 0,09500781 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04193612 0,09491843 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04193612 0,09482922 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04193612 0,09474018 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04193612 0,09465131 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04193612 0,0945626 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04193612 0,09447406 ! mannose metabolic process GO:0006013 13 9 0,000 0,04193612 0,09438568 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04193612 0,09429747 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04193612 0,09420943 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04193612 0,09412154 ! receptor clustering GO:0043113 18 9 0,000 0,04193612 0,09403383 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04193612 0,09394627 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04193612 0,09385888 ! ruffle organization GO:0031529 15 9 0,000 0,04193612 0,09377165 ! retinol metabolic process GO:0042572 18 9 0,000 0,04193612 0,09368458 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04193612 0,09359768 ! behavioral fear response GO:0001662 22 9 0,000 0,04193612 0,09351093 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04193612 0,09342435 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04193612 0,09333792 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04193612 0,09325166 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,04193612 0,09316555 ! protein heterooligomerization GO:0051291 16 9 0,000 0,04193612 0,09307961 ! oligodendrocyte development GO:0014003 10 9 0,000 0,04193612 0,09299382 ! segment specification GO:0007379 13 9 0,000 0,04193612 0,09290819 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04193612 0,09282272 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04193612 0,0927374 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04193612 0,09265224 ! response to amine stimulus GO:0014075 13 9 0,000 0,04193612 0,09256724 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04193612 0,0924824 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04193612 0,09239771 ! erythrocyte development GO:0048821 15 9 0,000 0,04193612 0,09231317 ! gas homeostasis GO:0033483 16 9 0,000 0,04193612 0,09222879 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04193612 0,09214456 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04193612 0,09206049 ! renal water homeostasis GO:0003091 14 9 0,000 0,04193612 0,09197657 ! postreplication repair GO:0006301 22 9 0,000 0,04193612 0,0918928 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04193612 0,09180919 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04193612 0,09172572 ! icosanoid secretion GO:0032309 15 9 0,000 0,04193612 0,09164241 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04193612 0,09155925 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04193612 0,09147624 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04193612 0,09139338 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04193612 0,09131067 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04193612 0,09122811 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04193612 0,0911457 ! sterol catabolic process GO:0016127 11 9 0,000 0,04193612 0,09106344 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04193612 0,09098133 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04193612 0,09089936 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04193612 0,09081755 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04193612 0,09073588 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04193612 0,09065435 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,04193612 0,09057298 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04193612 0,09049174 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04193612 0,09041066 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04193612 0,09032972 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04193612 0,09024892 ! purine base metabolic process GO:0006144 21 9 0,000 0,04193612 0,09016827 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04193612 0,09008776 ! pigment granule transport GO:0051904 17 9 0,000 0,04193612 0,0900074 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04193612 0,08992718 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,04193612 0,0898471 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04193612 0,08976717 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04193612 0,08968737 ! negative regulation of cell size GO:0045792 134 69 1,000 0,04270681 0,09125453 ! appendage morphogenesis GO:0035107 135 70 1,000 0,04382913 0,09356955 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 1,000 0,04496237 0,09590377 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 1,000 0,04496237 0,09581882 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,04496237 0,09573403 ! acute inflammatory response GO:0002526 113 72 1,000 0,0461064 0,09808311 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,0461064 0,09799646 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04648651 0,09871715 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04648651 0,0986301 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,04648651 0,0985432 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,04648651 0,09845645 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04648651 0,09836986 ! synapsis GO:0007129 13 10 0,000 0,04648651 0,09828342 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04648651 0,09819713 ! N-glycan processing GO:0006491 20 10 0,000 0,04648651 0,09811099 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04648651 0,09802501 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,04648651 0,09793917 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04648651 0,09785348 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04648651 0,09776795 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04648651 0,09768256 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04648651 0,09759732 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04648651 0,09751223 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04648651 0,09742729 ! androgen metabolic process GO:0008209 17 10 0,000 0,04648651 0,0973425 ! phospholipid efflux GO:0033700 16 10 0,000 0,04648651 0,09725785 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04648651 0,09717336 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04648651 0,097089 ! lung alveolus development GO:0048286 26 10 0,000 0,04648651 0,0970048 ! pathogenesis GO:0009405 13 10 0,000 0,04648651 0,09692074 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04648651 0,09683682 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04648651 0,09675306 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,04648651 0,09666943 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04648651 0,09658595 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04648651 0,09650262 ! endoderm development GO:0007492 16 10 0,000 0,04648651 0,09641942 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04648651 0,09633638 ! arginine catabolic process GO:0006527 13 10 0,000 0,04648651 0,09625347 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04648651 0,09617071 ! proline metabolic process GO:0006560 13 10 0,000 0,04648651 0,09608809 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04648651 0,09600561 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,04648651 0,09592327 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04648651 0,09584107 ! V(D)J recombination GO:0033151 28 10 0,000 0,04648651 0,09575902 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04648651 0,0956771 ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04648651 0,09559533 ! B cell proliferation GO:0042100 18 10 0,000 0,04648651 0,09551369 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04648651 0,09543219 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04648651 0,09535084 ! multicellular organism growth GO:0035264 18 10 0,000 0,04648651 0,09526962 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04648651 0,09518854 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04648651 0,0951076 ! epithelial cell development GO:0002064 20 10 0,000 0,04648651 0,09502679 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04648651 0,09494612 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04648651 0,09486559 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04648651 0,0947852 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04648651 0,09470494 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04648651 0,09462482 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04648651 0,09454483 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,04648651 0,09446498 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04648651 0,09438526 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04648651 0,09430568 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04648651 0,09422623 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04648651 0,09414691 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04648651 0,09406773 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04648651 0,09398868 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,04648651 0,09390977 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04648651 0,09383098 ! DNA ligation GO:0006266 19 10 0,000 0,04648651 0,09375233 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04648651 0,09367381 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04648651 0,09359542 ! melanosome localization GO:0032400 16 10 0,000 0,04648651 0,09351717 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04648651 0,09343904 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04648651 0,09336105 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04648651 0,09328318 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04648651 0,09320544 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04648651 0,09312784 ! mRNA cleavage GO:0006379 17 10 0,000 0,04648651 0,09305036 ! protein sumoylation GO:0016925 15 10 0,000 0,04648651 0,09297301 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04648651 0,09289579 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04648651 0,0928187 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04648651 0,09274173 ! salivary gland development GO:0007431 27 10 0,000 0,04648651 0,0926649 ! prophase GO:0051324 15 10 0,000 0,04648651 0,09258819 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04648651 0,09251161 ! apical protein localization GO:0045176 15 10 0,000 0,04648651 0,09243515 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04648651 0,09235882 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04648651 0,09228262 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,04648651 0,09220654 ! midbrain development GO:0030901 13 10 0,000 0,04648651 0,09213059 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04648651 0,09205476 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04648651 0,09197906 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04648651 0,09190348 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04648651 0,09182802 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04648651 0,09175269 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04648651 0,09167749 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04648651 0,0916024 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,04648651 0,09152744 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,04648651 0,0914526 ! oocyte development GO:0048599 17 10 0,000 0,04648651 0,09137789 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04648651 0,09130329 ! blastocyst formation GO:0001825 17 10 0,000 0,04648651 0,09122882 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04648651 0,09115447 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04648651 0,09108024 ! activation of innate immune response GO:0002218 12 10 0,000 0,04648651 0,09100613 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04648651 0,09093214 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04648651 0,09085827 ! response to nicotine GO:0035094 20 10 0,000 0,04648651 0,09078452 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04648651 0,09071089 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04648651 0,09063738 ! localization within membrane GO:0051668 20 10 0,000 0,04648651 0,09056399 ! axon guidance GO:0007411 139 73 1,000 0,0472611 0,09199855 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,04842634 0,09419061 ! organelle localization GO:0051640 136 74 1,000 0,04842634 0,09411452 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,049602 0,09632157 ! respiratory burst GO:0045730 17 11 0,000 0,05101543 0,0989864 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05101543 0,09890663 ! neuron fate specification GO:0048665 17 11 0,000 0,05101543 0,098827 ! telencephalon cell migration GO:0022029 20 11 0,000 0,05101543 0,09874749 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,05101543 0,09866811 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,05101543 0,09858886 ! thyroid gland development GO:0030878 26 11 0,000 0,05101543 0,09850974 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,05101543 0,09843074 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05101543 0,09835187 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05101543 0,09827312 ! response to pain GO:0048265 24 11 0,000 0,05101543 0,09819451 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,05101543 0,09811601 ! T cell proliferation GO:0042098 26 11 0,000 0,05101543 0,09803765 ! blood vessel remodeling GO:0001974 29 11 0,000 0,05101543 0,0979594 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,05101543 0,09788129 ! bone resorption GO:0045453 16 11 0,000 0,05101543 0,09780329 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,05101543 0,09772542 ! ventral spinal cord development GO:0021517 21 11 0,000 0,05101543 0,09764768 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05101543 0,09757006 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05101543 0,09749256 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05101543 0,09741518 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05101543 0,09733793 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05101543 0,0972608 ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,05101543 0,09718379 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,05101543 0,09710691 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,05101543 0,09703014 ! lipid digestion GO:0044241 18 11 0,000 0,05101543 0,0969535 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,05101543 0,09687698 ! UV protection GO:0009650 19 11 0,000 0,05101543 0,09680058 ! adult heart development GO:0007512 14 11 0,000 0,05101543 0,0967243 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,05101543 0,09664814 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05101543 0,09657209 ! temperature homeostasis GO:0001659 17 11 0,000 0,05101543 0,09649617 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05101543 0,09642037 ! negative regulation of ossification GO:0030279 26 11 0,000 0,05101543 0,09634469 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,05101543 0,09626912 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,05101543 0,09619368 ! pigment granule localization GO:0051875 20 11 0,000 0,05101543 0,09611835 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,05101543 0,09604314 ! vasoconstriction GO:0042310 18 11 0,000 0,05101543 0,09596805 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05101543 0,09589307 ! embryonic axis specification GO:0000578 18 11 0,000 0,05101543 0,09581821 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05101543 0,09574347 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05101543 0,09566885 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05101543 0,09559434 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,05101543 0,09551995 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05101543 0,09544567 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05101543 0,09537151 ! zymogen activation GO:0031638 15 11 0,000 0,05101543 0,09529746 ! neuroblast proliferation GO:0007405 24 11 0,000 0,05101543 0,09522353 ! nucleosome positioning GO:0016584 15 11 0,000 0,05101543 0,09514972 ! regulation of isotype switching GO:0045191 22 11 0,000 0,05101543 0,09507601 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,05101543 0,09500242 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,05101543 0,09492895 ! acid secretion GO:0046717 18 11 0,000 0,05101543 0,09485559 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05101543 0,09478234 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,05101543 0,09470921 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,05101543 0,09463619 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,05101543 0,09456328 ! oocyte differentiation GO:0009994 18 11 0,000 0,05101543 0,09449048 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,05101543 0,09441779 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,05101543 0,09434522 ! cholesterol efflux GO:0033344 19 11 0,000 0,05101543 0,09427276 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05101543 0,09420041 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05101543 0,09412817 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,05101543 0,09405604 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,05101543 0,09398402 ! embryonic gut development GO:0048566 15 11 0,000 0,05101543 0,09391211 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,05101543 0,09384032 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05101543 0,09376863 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,05101543 0,09369705 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,05101543 0,09362558 ! defense response to fungus GO:0050832 13 11 0,000 0,05101543 0,09355422 ! developmental induction GO:0031128 19 11 0,000 0,05101543 0,09348296 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,05101543 0,09341182 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05101543 0,09334079 ! sequestering of metal ion GO:0051238 14 11 0,000 0,05101543 0,09326986 ! lamellipodium assembly GO:0030032 20 11 0,000 0,05101543 0,09319904 ! regulation of embryonic development GO:0045995 27 11 0,000 0,05101543 0,09312833 ! nucleus localization GO:0051647 19 11 0,000 0,05101543 0,09305772 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05101543 0,09298722 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,05198409 0,09468109 ! blood coagulation GO:0007596 146 78 1,000 0,05319027 0,09680468 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,05319027 0,09673151 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,05440638 0,09886839 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,055523 0,10082139 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,055523 0,10074535 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,055523 0,10066943 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,055523 0,10059363 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,055523 0,10051794 ! virus-host interaction GO:0019048 29 12 0,000 0,055523 0,10044236 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,055523 0,10036689 ! cartilage condensation GO:0001502 20 12 0,000 0,055523 0,10029154 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,055523 0,10021631 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,055523 0,10014118 ! protein complex disassembly GO:0043241 27 12 0,000 0,055523 0,10006617 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,055523 0,09999127 ! hippocampus development GO:0021766 26 12 0,000 0,055523 0,09991648 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,055523 0,09984181 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,055523 0,09976724 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,055523 0,09969279 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,055523 0,09961845 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,055523 0,09954422 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,055523 0,09947009 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,055523 0,09939608 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,055523 0,09932218 ! drug transport GO:0015893 16 12 0,000 0,055523 0,09924839 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,055523 0,09917471 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,055523 0,09910114 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,055523 0,09902768 ! polyamine metabolic process GO:0006595 17 12 0,000 0,055523 0,09895432 ! focal adhesion formation GO:0048041 35 12 0,000 0,055523 0,09888108 ! mitotic spindle organization GO:0007052 21 12 0,000 0,055523 0,09880794 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,055523 0,09873491 ! forebrain cell migration GO:0021885 21 12 0,000 0,055523 0,09866199 ! asymmetric protein localization GO:0008105 20 12 0,000 0,055523 0,09858918 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,055523 0,09851647 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,055523 0,09844387 ! entry into host cell GO:0030260 32 12 0,000 0,055523 0,09837138 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,055523 0,098299 ! monoamine transport GO:0015844 18 12 0,000 0,055523 0,09822672 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,055523 0,09815455 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,055523 0,09808248 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,055523 0,09801052 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,055523 0,09793866 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,055523 0,09786691 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,055523 0,09779527 ! protein homotetramerization GO:0051289 21 12 0,000 0,055523 0,09772373 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,055523 0,09765229 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,055523 0,09758096 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,055523 0,09750974 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,055523 0,09743861 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,055523 0,09736759 ! cranial nerve development GO:0021545 20 12 0,000 0,055523 0,09729668 ! fucose catabolic process GO:0019317 22 12 0,000 0,055523 0,09722586 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,055523 0,09715515 ! histone acetylation GO:0016573 26 12 0,000 0,055523 0,09708455 ! histone methylation GO:0016571 26 12 0,000 0,055523 0,09701404 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,055523 0,09694364 ! autonomic nervous system development GO:0048483 24 12 0,000 0,055523 0,09687334 ! gland morphogenesis GO:0022612 29 12 0,000 0,055523 0,09680314 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,055523 0,09673305 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,055523 0,09666305 ! T cell homeostasis GO:0043029 25 12 0,000 0,055523 0,09659316 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,055523 0,09652337 ! spleen development GO:0048536 22 12 0,000 0,055523 0,09645367 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,055523 0,09638408 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,055523 0,09631459 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,055523 0,0962452 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,055523 0,09617591 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,055523 0,09610672 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,055523 0,09603763 ! response to cold GO:0009409 17 12 0,000 0,055523 0,09596863 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,055523 0,09589974 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,055523 0,09583094 ! response to metal ion GO:0010038 140 80 1,000 0,0556323 0,09595076 ! T cell activation GO:0042110 168 81 1,000 0,05686791 0,09801159 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,05686791 0,09794143 GO:0045937|positive regulation of phosphate metabolic process, ! cGMP metabolic process GO:0046068 18 13 0,000 0,0600093 0,10327782 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,0600093 0,10320399 ! regulation of chemokine production GO:0032642 18 13 0,000 0,0600093 0,10313028 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,0600093 0,10305666 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,0600093 0,10298316 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,0600093 0,10290976 ! lipid localization GO:0010876 28 13 0,000 0,0600093 0,10283646 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,0600093 0,10276326 ! organelle fusion GO:0048284 32 13 0,000 0,0600093 0,10269018 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,0600093 0,10261719 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,0600093 0,10254431 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,0600093 0,10247153 ! endocrine pancreas development GO:0031018 22 13 0,000 0,0600093 0,10239886 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,0600093 0,10232628 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,0600093 0,10225382 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,0600093 0,10218145 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,0600093 0,10210918 ! methionine metabolic process GO:0006555 27 13 0,000 0,0600093 0,10203702 ! plasma membrane organization GO:0007009 24 13 0,000 0,0600093 0,10196496 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,0600093 0,101893 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,0600093 0,10182115 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,0600093 0,10174939 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,0600093 0,10167774 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,0600093 0,10160618 ! response to X-ray GO:0010165 25 13 0,000 0,0600093 0,10153473 ! cytokine metabolic process GO:0042107 22 13 0,000 0,0600093 0,10146338 ! exocrine system development GO:0035272 32 13 0,000 0,0600093 0,10139213 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,0600093 0,10132097 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,0600093 0,10124992 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,0600093 0,10117897 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,0600093 0,10110811 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,0600093 0,10103736 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,0600093 0,1009667 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,0600093 0,10089615 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,0600093 0,10082569 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,0600093 0,10075533 ! regulation of cellular pH GO:0030641 22 13 0,000 0,0600093 0,10068507 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,0600093 0,1006149 ! ribosome assembly GO:0042255 17 13 0,000 0,0600093 0,10054484 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,0600093 0,10047487 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,0600093 0,100405 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,0600093 0,10033522 ! chromatin silencing GO:0006342 26 13 0,000 0,0600093 0,10026555 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,0600093 0,10019597 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,0600093 0,10012648 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,0600093 0,10005709 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,0600093 0,0999878 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,0600093 0,09991861 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,0600093 0,09984951 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,0600093 0,0997805 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,0600093 0,09971159 ! embryonic placenta development GO:0001892 23 13 0,000 0,0600093 0,09964278 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,0600093 0,09957406 ! insulin secretion GO:0030073 23 13 0,000 0,0600093 0,09950544 ! actin filament polymerization GO:0030041 24 13 0,000 0,0600093 0,09943691 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,0600093 0,09936847 ! acrosome reaction GO:0007340 18 13 0,000 0,0600093 0,09930013 ! hemostasis GO:0007599 158 84 1,000 0,0606317 0,10026107 ! response to unfolded protein GO:0006986 131 85 1,000 0,06190489 0,10229614 ! response to inorganic substance GO:0010035 153 86 1,000 0,0631872 0,10434345 ! tube morphogenesis GO:0035239 176 86 1,000 0,0631872 0,10427188 ! mitochondrion organization GO:0007005 148 86 1,000 0,0631872 0,10420041 ! rRNA transcription GO:0009303 25 14 0,000 0,06447445 0,10625036 ! lactation GO:0007595 26 14 0,000 0,06447445 0,10617763 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,06447445 0,10610501 ! reproductive cellular process GO:0048610 20 14 0,000 0,06447445 0,10603248 ! tRNA modification GO:0006400 20 14 0,000 0,06447445 0,10596006 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,06447445 0,10588773 ! regulation of S phase GO:0033261 23 14 0,000 0,06447445 0,1058155 ! water transport GO:0006833 21 14 0,000 0,06447445 0,10574337 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,06447445 0,10567134 ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,06447445 0,1055994 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,06447445 0,10552757 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,06447445 0,10545583 ! RNA polyadenylation GO:0043631 30 14 0,000 0,06447445 0,10538419 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,06447445 0,10531264 ! regulated secretory pathway GO:0045055 23 14 0,000 0,06447445 0,10524119 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,06447445 0,10516985 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,06447445 0,10509859 ! arginine metabolic process GO:0006525 17 14 0,000 0,06447445 0,10502743 ! regulation of heart rate GO:0002027 24 14 0,000 0,06447445 0,10495637 ! organic alcohol transport GO:0015850 29 14 0,000 0,06447445 0,10488541 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,06447445 0,10481454 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,06447445 0,10474377 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,06447445 0,10467309 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,06447445 0,10460251 ! neutral amino acid transport GO:0015804 26 14 0,000 0,06447445 0,10453202 ! L-amino acid transport GO:0015807 30 14 0,000 0,06447445 0,10446163 ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,06447445 0,10439133 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,06447445 0,10432113 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06447445 0,10425102 ! cerebellum development GO:0021549 21 14 0,000 0,06447445 0,10418101 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,06447445 0,10411109 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,06447445 0,10404126 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,06447445 0,10397153 ! cofactor transport GO:0051181 26 14 0,000 0,06447445 0,10390189 ! NADP metabolic process GO:0006739 24 14 0,000 0,06447445 0,10383234 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,06447445 0,10376289 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,06447445 0,10369353 ! intestinal absorption GO:0050892 25 14 0,000 0,06447445 0,10362426 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,06447445 0,10355509 ! oxygen transport GO:0015671 21 14 0,000 0,06447445 0,103486 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06447445 0,10341701 ! male genitalia development GO:0030539 24 14 0,000 0,06447445 0,10334812 ! regulation of RNA stability GO:0043487 32 14 0,000 0,06447445 0,10327931 ! regulation of axon extension GO:0030516 37 14 0,000 0,06447445 0,10321059 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,06447445 0,10314197 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,06447445 0,10307344 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,06708763 0,10717984 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06891853 0,11003184 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06891853 0,10995887 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,06891853 0,109886 ! superoxide anion generation GO:0042554 20 15 0,000 0,06891853 0,10981323 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,06891853 0,10974056 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,06891853 0,10966798 ! copper ion transport GO:0006825 20 15 0,000 0,06891853 0,10959549 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,06891853 0,1095231 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,06891853 0,10945081 ! sulfate transport GO:0008272 23 15 0,000 0,06891853 0,10937861 ! response to cAMP GO:0051591 22 15 0,000 0,06891853 0,10930651 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,06891853 0,10923451 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,06891853 0,10916259 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,06891853 0,10909078 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,06891853 0,10901905 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,06891853 0,10894742 ! response to hexose stimulus GO:0009746 22 15 0,000 0,06891853 0,10887589 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,06891853 0,10880445 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,06891853 0,1087331 ! pituitary gland development GO:0021983 29 15 0,000 0,06891853 0,10866185 ! vesicle coating GO:0006901 33 15 0,000 0,06891853 0,10859069 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,06891853 0,10851962 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,06891853 0,10844865 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,06891853 0,10837776 ! regulation of exocytosis GO:0017157 22 15 0,000 0,06891853 0,10830698 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,06891853 0,10823628 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,06891853 0,10816567 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,06891853 0,10809516 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,06891853 0,10802474 ! regulation of vasodilation GO:0042312 26 15 0,000 0,06891853 0,10795441 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,06891853 0,10788418 ! histone deacetylation GO:0016575 20 15 0,000 0,06891853 0,10781403 ! mRNA splice site selection GO:0006376 38 15 0,000 0,06891853 0,10774398 ! tissue regeneration GO:0042246 26 15 0,000 0,06891853 0,10767401 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,06891853 0,10760414 ! water homeostasis GO:0030104 27 15 0,000 0,06891853 0,10753436 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06891853 0,10746467 ! muscle maintenance GO:0046716 26 15 0,000 0,06891853 0,10739506 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,06891853 0,10732555 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,06891853 0,10725613 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,06891853 0,1071868 ! dopamine metabolic process GO:0042417 35 15 0,000 0,06891853 0,10711756 ! heme biosynthetic process GO:0006783 29 15 0,000 0,06891853 0,1070484 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,06891853 0,10697934 ! detection of bacterium GO:0016045 18 15 0,000 0,06891853 0,10691037 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,06891853 0,10684148 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,06891853 0,10677268 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,06891853 0,10670398 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,06891853 0,10663536 ! peptide hormone processing GO:0016486 23 15 0,000 0,06891853 0,10656682 ! response to protein stimulus GO:0051789 149 91 1,000 0,0697314 0,1077545 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,07334164 0,11326059 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,07334164 0,11318794 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,07334164 0,11311538 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,07334164 0,11304292 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,07334164 0,11297055 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,07334164 0,11289827 ! bone remodeling GO:0046849 27 16 0,000 0,07334164 0,11282609 ! filopodium assembly GO:0046847 32 16 0,000 0,07334164 0,11275399 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,07334164 0,11268199 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,07334164 0,11261008 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,07334164 0,11253826 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,07334164 0,11246654 ! startle response GO:0001964 28 16 0,000 0,07334164 0,1123949 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,07334164 0,11232336 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,07334164 0,11225191 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,07334164 0,11218054 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,07334164 0,11210927 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,07334164 0,11203809 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,07334164 0,111967 ! protein polyubiquitination GO:0000209 34 16 0,000 0,07334164 0,111896 ! glutamate metabolic process GO:0006536 22 16 0,000 0,07334164 0,11182509 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,07334164 0,11175427 ! response to osmotic stress GO:0006970 25 16 0,000 0,07334164 0,11168354 ! lysosomal transport GO:0007041 26 16 0,000 0,07334164 0,1116129 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07334164 0,11154235 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07334164 0,11147189 ! intermediate filament-based process GO:0045103 32 16 0,000 0,07334164 0,11140151 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,07334164 0,11133123 ! negative regulation of immune response GO:0050777 35 16 0,000 0,07334164 0,11126103 ! axon cargo transport GO:0008088 43 16 0,000 0,07334164 0,11119092 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,07334164 0,1111209 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,07334164 0,11105097 ! DNA replication initiation GO:0006270 27 16 0,000 0,07334164 0,11098113 ! neuron recognition GO:0008038 35 16 0,000 0,07334164 0,11091137 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,07334164 0,11084171 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,07334164 0,11077213 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,07334164 0,11070263 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,07334164 0,11063323 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,07334164 0,11056391 GO:0046466|membrane lipid catabolic process, ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,07334164 0,11049468 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07334164 0,11042553 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,07334164 0,11035647 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,07334164 0,1102875 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,07334164 0,11021861 ! defense response to virus GO:0051607 37 16 0,000 0,07334164 0,11014981 ! female pregnancy GO:0007565 164 94 1,000 0,07376007 0,11070912 ! regulation of T cell activation GO:0050863 158 94 1,000 0,07376007 0,1106401 ! detection of stimulus GO:0051606 151 96 1,000 0,0764866 0,11465842 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,0777439 0,11647062 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,0777439 0,11639814 ! metencephalon development GO:0022037 30 17 0,000 0,0777439 0,11632575 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,0777439 0,11625346 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,0777439 0,11618125 ! signal complex assembly GO:0007172 41 17 0,000 0,0777439 0,11610913 ! endothelial cell migration GO:0043542 28 17 0,000 0,0777439 0,1160371 ! inositol metabolic process GO:0006020 28 17 0,000 0,0777439 0,11596517 ! gene silencing by RNA GO:0031047 36 17 0,000 0,0777439 0,11589332 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,0777439 0,11582156 ! glial cell development GO:0021782 27 17 0,000 0,0777439 0,11574988 ! limbic system development GO:0021761 36 17 0,000 0,0777439 0,1156783 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,0777439 0,11560681 ! adult walking behavior GO:0007628 33 17 0,000 0,0777439 0,1155354 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,0777439 0,11546408 ! heart looping GO:0001947 30 17 0,000 0,0777439 0,11539285 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,0777439 0,11532171 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,0777439 0,11525065 ! myoblast differentiation GO:0045445 45 17 0,000 0,0777439 0,11517969 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,0777439 0,11510881 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,0777439 0,11503801 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,0777439 0,11496731 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,0777439 0,11489669 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,0777439 0,11482616 ! glycine metabolic process GO:0006544 28 17 0,000 0,0777439 0,11475571 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,0777439 0,11468535 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,0777439 0,11461508 ! NAD metabolic process GO:0019674 29 17 0,000 0,0777439 0,11454489 ! membrane budding GO:0006900 37 17 0,000 0,0777439 0,11447479 ! DNA integration GO:0015074 29 17 0,000 0,0777439 0,11440478 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,0777439 0,11433485 ! regulation of protein binding GO:0043393 33 17 0,000 0,0777439 0,114265 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,0777439 0,11419525 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,0777439 0,11412557 ! genitalia development GO:0048806 30 17 0,000 0,0777439 0,11405598 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,0777439 0,11398648 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,0777439 0,11391706 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,0777439 0,11384772 ! steroid catabolic process GO:0006706 31 17 0,000 0,0777439 0,11377847 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,0777439 0,11370931 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,0777439 0,11364023 ! gas transport GO:0015669 25 17 0,000 0,0777439 0,11357123 ! organic cation transport GO:0015695 31 17 0,000 0,0777439 0,11350231 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,0777439 0,11343348 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,0777439 0,11336473 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,0777439 0,11329607 ! microspike assembly GO:0030035 36 17 0,000 0,0777439 0,11322749 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,08212538 0,11953639 ! neuron maturation GO:0042551 42 18 0,000 0,08212538 0,11946412 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,08212538 0,11939194 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,08212538 0,11931984 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,08212538 0,11924783 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,08212538 0,11917591 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,08212538 0,11910407 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,08212538 0,11903232 ! memory GO:0007613 31 18 0,000 0,08212538 0,11896066 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08212538 0,11888908 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,08212538 0,11881759 ! patterning of blood vessels GO:0001569 39 18 0,000 0,08212538 0,11874619 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,08212538 0,11867487 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,08212538 0,11860364 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,08212538 0,11853249 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08212538 0,11846143 ! response to retinoic acid GO:0032526 26 18 0,000 0,08212538 0,11839045 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,08212538 0,11831956 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,08212538 0,11824875 ! response to fungus GO:0009620 21 18 0,000 0,08212538 0,11817803 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,08212538 0,11810739 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,08212538 0,11803683 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,08212538 0,11796636 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,08212538 0,11789598 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,08212538 0,11782568 ! vitamin transport GO:0051180 27 18 0,000 0,08212538 0,11775546 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,08212538 0,11768532 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,08212538 0,11761527 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,08212538 0,11754531 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,08212538 0,11747542 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,08212538 0,11740562 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,08212538 0,1173359 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,08212538 0,11726627 ! protein secretion GO:0009306 39 19 0,000 0,08648619 0,12341979 ! positive regulation of translation GO:0045727 30 19 0,000 0,08648619 0,12334663 ! negative regulation of defense response GO:0031348 25 19 0,000 0,08648619 0,12327356 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,08648619 0,12320058 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,08648619 0,12312768 ! lipid phosphorylation GO:0046834 35 19 0,000 0,08648619 0,12305486 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,08648619 0,12298213 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,08648619 0,12290949 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,08648619 0,12283694 ! bile acid metabolic process GO:0008206 29 19 0,000 0,08648619 0,12276447 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,08648619 0,12269208 ! cerebral cortex development GO:0021987 36 19 0,000 0,08648619 0,12261978 ! pigmentation during development GO:0048066 41 19 0,000 0,08648619 0,12254757 ! response to vitamin A GO:0033189 27 19 0,000 0,08648619 0,12247544 ! heme metabolic process GO:0042168 36 19 0,000 0,08648619 0,1224034 ! actin filament bundle formation GO:0051017 42 19 0,000 0,08648619 0,12233144 ! neuromuscular junction development GO:0007528 34 19 0,000 0,08648619 0,12225956 ! plasma membrane fusion GO:0045026 28 19 0,000 0,08648619 0,12218777 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,08648619 0,12211606 ! peptide cross-linking GO:0018149 37 19 0,000 0,08648619 0,12204444 ! protein export from nucleus GO:0006611 36 19 0,000 0,08648619 0,1219729 ! heart process GO:0003015 30 19 0,000 0,08648619 0,12190145 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,08648619 0,12183008 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,08648619 0,12175879 ! visual learning GO:0008542 36 19 0,000 0,08648619 0,12168759 ! cellular pigmentation GO:0033059 36 19 0,000 0,08648619 0,12161647 ! G1 phase GO:0051318 40 19 0,000 0,08648619 0,12154543 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,08648619 0,12147447 ! cell-cell junction organization GO:0045216 35 19 0,000 0,08648619 0,1214036 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,08648619 0,12133281 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,08648619 0,1212621 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,08648619 0,12119148 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,08648619 0,12112094 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,08648619 0,12105048 ! cilium assembly GO:0042384 37 19 0,000 0,08648619 0,1209801 ! peptide hormone secretion GO:0030072 31 19 0,000 0,08648619 0,1209098 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,09082643 0,12690382 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,09082643 0,12683017 ! positive regulation of ossification GO:0045778 47 20 0,000 0,09082643 0,1267566 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,09082643 0,12668312 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,09082643 0,12660972 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,09082643 0,12653641 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,09082643 0,12646319 ! cAMP metabolic process GO:0046058 36 20 0,000 0,09082643 0,12639004 ! response to vitamin GO:0033273 31 20 0,000 0,09082643 0,12631698 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,09082643 0,12624401 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,09082643 0,12617112 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,09082643 0,12609832 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,09082643 0,1260256 ! response to alkaloid GO:0043279 38 20 0,000 0,09082643 0,12595296 ! retinoid metabolic process GO:0001523 32 20 0,000 0,09082643 0,12588041 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,09082643 0,12580794 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,09082643 0,12573555 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,09082643 0,12566325 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,09082643 0,12559103 GO:0032392|DNA geometric change, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,09082643 0,12551889 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,09082643 0,12544683 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,09082643 0,12537486 ! body fluid secretion GO:0007589 31 20 0,000 0,09082643 0,12530297 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,09082643 0,12523117 ! peptide secretion GO:0002790 35 20 0,000 0,09082643 0,12515944 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,09082643 0,1250878 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,09082643 0,12501624 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,09082643 0,12494476 ! sensory perception of pain GO:0019233 30 20 0,000 0,09082643 0,12487336 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,09082643 0,12480205 ! diencephalon development GO:0021536 34 20 0,000 0,09082643 0,12473081 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,09082643 0,12465966 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,09082643 0,12458859 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,09082643 0,1245176 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,09082643 0,12444669 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,09082643 0,12437586 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,09082643 0,12430511 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,09082643 0,12423444 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,09082643 0,12416385 ! regulation of glucose import GO:0046324 29 20 0,000 0,09082643 0,12409335 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,09082643 0,12402292 ! actin filament-based movement GO:0030048 43 20 0,000 0,09082643 0,12395257 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,09082643 0,1238823 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,09082643 0,12381212 ! negative regulation of translation GO:0017148 29 20 0,000 0,09082643 0,12374201 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,09082643 0,12367198 ! regulation of cell killing GO:0031341 42 21 0,000 0,09514619 0,12948061 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,09514619 0,12940742 ! hormone secretion GO:0046879 38 21 0,000 0,09514619 0,12933431 ! glycerol metabolic process GO:0006071 34 21 0,000 0,09514619 0,12926128 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,09514619 0,12918833 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,09514619 0,12911547 ! ovarian follicle development GO:0001541 35 21 0,000 0,09514619 0,12904269 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,09514619 0,12896999 ! smooth muscle contraction GO:0006939 46 21 0,000 0,09514619 0,12889737 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,09514619 0,12882483 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,09514619 0,12875238 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,09514619 0,12868 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,09514619 0,12860771 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,09514619 0,1285355 ! cytolysis GO:0019835 24 21 0,000 0,09514619 0,12846337 ! vasodilation GO:0042311 39 21 0,000 0,09514619 0,12839132 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,09514619 0,12831935 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,09514619 0,12824747 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,09514619 0,12817566 ! oogenesis GO:0048477 36 21 0,000 0,09514619 0,12810393 ! DNA modification GO:0006304 34 21 0,000 0,09514619 0,12803229 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,09514619 0,12796072 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,09514619 0,12788923 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,09514619 0,12781783 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,09514619 0,1277465 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,09514619 0,12767525 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,09514619 0,12760408 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,09514619 0,127533 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,09514619 0,12746199 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,09514619 0,12739106 ! sperm-egg recognition GO:0035036 21 21 0,000 0,09514619 0,1273202 ! gut development GO:0048565 39 21 0,000 0,09514619 0,12724943 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,09944557 0,13292557 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,09944557 0,13285177 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,09944557 0,13277804 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,09944557 0,1327044 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,09944557 0,13263084 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,09944557 0,13255736 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,09944557 0,13248396 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,09944557 0,13241064 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,09944557 0,13233741 ! regeneration GO:0031099 41 22 0,000 0,09944557 0,13226425 ! keratinization GO:0031424 28 22 0,000 0,09944557 0,13219118 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,09944557 0,13211818 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,09944557 0,13204527 ! sensory perception of taste GO:0050909 28 22 0,000 0,09944557 0,13197244 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,09944557 0,13189969 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,09944557 0,13182701 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,09944557 0,13175442 ! vacuolar transport GO:0007034 36 22 0,000 0,09944557 0,13168191 ! lysosome organization GO:0007040 41 22 0,000 0,09944557 0,13160948 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,09944557 0,13153713 ! fucose metabolic process GO:0006004 39 22 0,000 0,09944557 0,13146485 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,09944557 0,13139266 ! ureteric bud development GO:0001657 43 22 0,000 0,09944557 0,13132054 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,09944557 0,13124851 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,09944557 0,13117655 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,09944557 0,13110467 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,09944557 0,13103288 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,09944557 0,13096116 ! sarcomere organization GO:0045214 30 22 0,000 0,09944557 0,13088951 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,09944557 0,13081795 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,09944557 0,13074647 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,09944557 0,13067506 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,09944557 0,13060373 ! protein stabilization GO:0050821 39 22 0,000 0,09944557 0,13053248 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,10372466 0,13607499 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,10372466 0,13600083 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,10372466 0,13592676 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,10372466 0,13585276 ! gluconeogenesis GO:0006094 33 23 0,000 0,10372466 0,13577885 ! viral genome replication GO:0019079 41 23 0,000 0,10372466 0,13570502 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,10372466 0,13563126 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,10372466 0,13555759 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,10372466 0,135484 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,10372466 0,13541049 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,10372466 0,13533705 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,10372466 0,1352637 ! visual behavior GO:0007632 42 23 0,000 0,10372466 0,13519043 ! response to ethanol GO:0045471 46 23 0,000 0,10372466 0,13511723 ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,10372466 0,13504412 ! peroxisome organization GO:0007031 37 23 0,000 0,10372466 0,13497108 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,10372466 0,13489812 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,10372466 0,13482524 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,10372466 0,13475244 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,10372466 0,13467972 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,10372466 0,13460708 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,10372466 0,13453452 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,10372466 0,13446203 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,10372466 0,13438962 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,10372466 0,13431729 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,10372466 0,13424504 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,10372466 0,13417286 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,10372466 0,13410077 ! fatty acid transport GO:0015908 44 23 0,000 0,10372466 0,13402875 ! platelet activation GO:0030168 37 23 0,000 0,10372466 0,1339568 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,10372466 0,13388494 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,10372466 0,13381315 ! hormone transport GO:0009914 40 23 0,000 0,10372466 0,13374144 ! cell-cell recognition GO:0009988 25 23 0,000 0,10372466 0,13366981 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,10372466 0,13359825 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,10372466 0,13352677 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,10372466 0,13345536 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,10372466 0,13338403 GO:0006099|tricarboxylic acid cycle, ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,10798356 0,13878656 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,10798356 0,13871246 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,10798356 0,13863844 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,10798356 0,1385645 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,10798356 0,13849064 ! vesicle docking GO:0048278 47 24 0,000 0,10798356 0,13841686 ! spinal cord development GO:0021510 47 24 0,000 0,10798356 0,13834315 ! vacuole organization GO:0007033 43 24 0,000 0,10798356 0,13826953 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,10798356 0,13819598 ! digestive system process GO:0022600 39 24 0,000 0,10798356 0,13812251 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,10798356 0,13804912 ! regulation of behavior GO:0050795 43 24 0,000 0,10798356 0,13797581 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,10798356 0,13790257 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,10798356 0,13782941 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,10798356 0,13775633 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,10798356 0,13768333 ! membrane depolarization GO:0051899 39 24 0,000 0,10798356 0,1376104 ! pallium development GO:0021543 49 24 0,000 0,10798356 0,13753756 ! pentose metabolic process GO:0019321 35 24 0,000 0,10798356 0,13746479 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,10798356 0,13739209 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,10798356 0,13731947 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,10798356 0,13724693 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,10798356 0,13717447 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,10798356 0,13710208 GO:0033013|tetrapyrrole metabolic process, ! regulation of multi-organism process GO:0043900 36 24 0,000 0,10798356 0,13702977 ! regulation of amine transport GO:0051952 40 24 0,000 0,10798356 0,13695753 ! protein tetramerization GO:0051262 52 24 0,000 0,10798356 0,13688538 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,11222236 0,14218379 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,11222236 0,14210895 ! myelination GO:0042552 45 25 0,000 0,11222236 0,1420342 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,11222236 0,14195952 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,11222236 0,14188492 ! phototransduction GO:0007602 33 25 0,000 0,11222236 0,1418104 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,11222236 0,14173596 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,11222236 0,1416616 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,11222236 0,14158731 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,11222236 0,14151311 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,11222236 0,14143898 ! receptor metabolic process GO:0043112 46 25 0,000 0,11222236 0,14136493 ! chromosome condensation GO:0030261 45 25 0,000 0,11222236 0,14129095 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,11222236 0,14121705 ! negative regulation of cell development GO:0010721 73 25 0,000 0,11222236 0,14114323 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,11222236 0,14106949 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,11222236 0,14099583 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,11222236 0,14092224 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,11222236 0,14084873 ! immunoglobulin production GO:0002377 55 25 0,000 0,11222236 0,14077529 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,11222236 0,14070193 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,11222236 0,14062865 ! neural tube closure GO:0001843 49 25 0,000 0,11222236 0,14055544 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,11222236 0,14048231 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,11644117 0,1456877 ! embryonic pattern specification GO:0009880 44 26 0,000 0,11644117 0,14561198 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,11644117 0,14553634 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,11644117 0,14546077 ! initiation of viral infection GO:0019059 57 26 0,000 0,11644117 0,14538529 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,11644117 0,14530988 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,11644117 0,14523455 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,11644117 0,1451593 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,11644117 0,14508413 ! tube lumen formation GO:0035148 50 26 0,000 0,11644117 0,14500903 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,11644117 0,14493401 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,11644117 0,14485907 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,11644117 0,14478421 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,11644117 0,14470942 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,11644117 0,14463472 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,11644117 0,14456009 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,11644117 0,14448553 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,11644117 0,14441105 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,11644117 0,14433665 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,11644117 0,14426233 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,11644117 0,14418808 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,11644117 0,14411391 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,11644117 0,14403982 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,11644117 0,1439658 ! blastocyst development GO:0001824 49 26 0,000 0,11644117 0,14389186 ! leukocyte proliferation GO:0070661 52 26 0,000 0,11644117 0,14381799 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,11644117 0,1437442 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,11644117 0,14367049 ! neuron fate commitment GO:0048663 48 27 0,000 0,12064006 0,14877498 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,12064006 0,14869876 ! iron ion transport GO:0006826 59 27 0,000 0,12064006 0,14862262 ! protein amino acid acylation GO:0043543 55 27 0,000 0,12064006 0,14854656 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,12064006 0,14847058 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,12064006 0,14839468 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,12064006 0,14831885 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,12064006 0,1482431 ! male gonad development GO:0008584 44 27 0,000 0,12064006 0,14816742 ! response to toxin GO:0009636 47 27 0,000 0,12064006 0,14809183 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,12064006 0,14801631 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,12064006 0,14794087 ! glutathione metabolic process GO:0006749 39 27 0,000 0,12064006 0,1478655 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,12064006 0,14779022 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,12064006 0,14771501 ! circadian rhythm GO:0007623 50 28 0,000 0,12481914 0,15275425 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,12481914 0,15267659 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,12481914 0,15259901 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,12481914 0,15252151 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,12481914 0,15244409 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,12481914 0,15236674 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,12481914 0,15228948 ! synaptogenesis GO:0007416 42 28 0,000 0,12481914 0,15221229 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,12481914 0,15213518 ! lipid oxidation GO:0034440 43 28 0,000 0,12481914 0,15205815 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,12481914 0,1519812 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,12481914 0,15190432 ! translational initiation GO:0006413 65 29 0,000 0,12897849 0,15688688 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,12897849 0,15680761 ! regulation of pH GO:0006885 43 29 0,000 0,12897849 0,15672841 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,12897849 0,1566493 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,12897849 0,15657026 ! catechol metabolic process GO:0009712 54 29 0,000 0,12897849 0,15649131 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,12897849 0,15641243 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,12897849 0,15633363 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,12897849 0,15625491 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,12897849 0,15617628 ! cell fate determination GO:0001709 60 29 0,000 0,12897849 0,15609772 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,12897849 0,15601924 ! detection of light stimulus GO:0009583 38 29 0,000 0,12897849 0,15594083 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,12897849 0,15586251 ! tissue homeostasis GO:0001894 48 29 0,000 0,12897849 0,15578427 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,13311822 0,16070368 ! zinc ion transport GO:0006829 45 30 0,000 0,13311822 0,16062309 ! membrane docking GO:0022406 61 30 0,000 0,13311822 0,16054258 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,13311822 0,16046214 ! cell junction assembly GO:0034329 78 30 0,000 0,13311822 0,16038179 ! regulation of innate immune response GO:0045088 51 30 0,000 0,13311822 0,16030152 ! acute-phase response GO:0006953 49 30 0,000 0,13311822 0,16022133 ! myofibril assembly GO:0030239 47 30 0,000 0,13311822 0,16014122 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,13311822 0,16006119 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,13311822 0,15998124 ! phospholipid transport GO:0015914 51 30 0,000 0,13311822 0,15990137 ! ensheathment of neurons GO:0007272 57 30 0,000 0,13311822 0,15982158 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,13311822 0,15974186 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,13311822 0,15966223 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,13311822 0,15958268 ! eye morphogenesis GO:0048592 60 30 0,000 0,13311822 0,15950321 ! response to heat GO:0009408 50 30 0,000 0,13311822 0,15942381 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,13723841 0,16427642 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,13723841 0,16419473 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,13723841 0,16411313 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,13723841 0,1640316 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,13723841 0,16395015 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,13723841 0,16386879 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,13723841 0,16378751 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,13723841 0,1637063 ! ovulation cycle process GO:0022602 49 31 0,000 0,13723841 0,16362518 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,13723841 0,16354414 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,13723841 0,16346317 ! peptide transport GO:0015833 55 31 0,000 0,13723841 0,16338229 ! iron ion homeostasis GO:0055072 54 31 0,000 0,13723841 0,16330149 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,13723841 0,16322077 ! mesoderm formation GO:0001707 69 31 0,000 0,13723841 0,16314012 ! natural killer cell activation GO:0030101 45 31 0,000 0,13723841 0,16305956 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,13723841 0,16297908 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,13723841 0,16289867 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,13723841 0,16281835 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,13723841 0,1627381 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,14133915 0,16751822 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,14133915 0,16743574 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,14133915 0,16735334 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,14133915 0,16727103 ! cholesterol transport GO:0030301 56 32 0,000 0,14133915 0,16718879 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,14133915 0,16710663 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,14133915 0,16702456 ! metanephros development GO:0001656 74 32 0,000 0,14133915 0,16694256 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,14133915 0,16686065 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,14133915 0,16677881 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,14133915 0,16669706 ! muscle cell development GO:0055001 49 32 0,000 0,14133915 0,16661538 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,14133915 0,16653379 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,14133915 0,16645227 ! ovulation cycle GO:0042698 51 32 0,000 0,14133915 0,16637084 ! peripheral nervous system development GO:0007422 64 32 0,000 0,14133915 0,16628948 ! BMP signaling pathway GO:0030509 64 32 0,000 0,14133915 0,16620821 ! hindbrain development GO:0030902 61 32 0,000 0,14133915 0,16612701 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,14133915 0,1660459 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,14133915 0,16596486 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,14133915 0,1658839 ! gene silencing GO:0016458 65 32 0,000 0,14133915 0,16580302 ! post-embryonic development GO:0009791 69 33 0,000 0,14542054 0,1705077 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,14542054 0,17042465 ! protein targeting to membrane GO:0006612 68 33 0,000 0,14542054 0,17034168 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,14542054 0,17025879 ! ceramide metabolic process GO:0006672 64 33 0,000 0,14542054 0,17017598 ! formation of primary germ layer GO:0001704 72 33 0,000 0,14542054 0,17009325 ! cell fate specification GO:0001708 52 33 0,000 0,14542054 0,1700106 ! sterol transport GO:0015918 57 33 0,000 0,14542054 0,16992803 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,14542054 0,16984554 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,14542054 0,16976313 ! adult locomotory behavior GO:0008344 59 33 0,000 0,14542054 0,1696808 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,14542054 0,16959855 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,14542054 0,16951638 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,14948266 0,1741672 ! glial cell differentiation GO:0010001 63 34 0,000 0,14948266 0,1740829 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,14948266 0,17399868 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,14948266 0,17391454 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,14948266 0,17383049 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,14948266 0,17374651 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,14948266 0,17366261 ! mismatch repair GO:0006298 46 34 0,000 0,14948266 0,1735788 ! spermatid development GO:0007286 63 34 0,000 0,14948266 0,17349507 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,14948266 0,17341141 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,14948266 0,17332784 ! placenta development GO:0001890 53 34 0,000 0,14948266 0,17324435 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,1535256 0,1778443 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,1535256 0,17775871 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,1535256 0,17767321 ! odontogenesis GO:0042476 66 35 0,000 0,1535256 0,17758779 ! female gonad development GO:0008585 58 35 0,000 0,1535256 0,17750245 ! telencephalon development GO:0021537 68 35 0,000 0,1535256 0,1774172 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,1535256 0,17733202 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,1535256 0,17724693 ! cytokine production GO:0001816 59 35 0,000 0,1535256 0,17716192 ! vesicle localization GO:0051648 64 35 0,000 0,1535256 0,17707699 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,15754947 0,18163106 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,15754947 0,18154407 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,15754947 0,18145717 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,15754947 0,18137034 ! cell junction organization GO:0034330 86 36 0,000 0,15754947 0,18128361 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,15754947 0,18119695 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,15754947 0,18111038 ! positive regulation of cell development GO:0010720 80 36 0,000 0,15754947 0,18102389 ! regulation of proteolysis GO:0030162 72 36 0,000 0,15754947 0,18093748 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,15754947 0,18085115 ! aerobic respiration GO:0009060 55 36 0,000 0,15754947 0,18076491 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,15754947 0,18067875 ! embryonic organ development GO:0048568 57 36 0,000 0,15754947 0,18059267 ! RNA export from nucleus GO:0006405 56 37 0,000 0,16155434 0,18509511 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,16155434 0,18500701 ! sister chromatid segregation GO:0000819 58 37 0,000 0,16155434 0,184919 ! actomyosin structure organization GO:0031032 62 37 0,000 0,16155434 0,18483107 ! organic anion transport GO:0015711 68 37 0,000 0,16155434 0,18474322 ! tissue remodeling GO:0048771 76 37 0,000 0,16155434 0,18465545 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,16155434 0,18456777 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,16155434 0,18448018 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,16155434 0,18439266 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,16155434 0,18430523 ! pigment metabolic process GO:0042440 80 37 0,000 0,16155434 0,18421788 ! spermatid differentiation GO:0048515 66 37 0,000 0,16155434 0,18413062 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,16155434 0,18404343 ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,1655403 0,18849501 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,1655403 0,18840584 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,1655403 0,18831676 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,1655403 0,18822777 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,1655403 0,18813885 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,1655403 0,18805003 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,1655403 0,18796128 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,1655403 0,18787262 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,1655403 0,18778404 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,1655403 0,18769555 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,1655403 0,18760714 ! glucan metabolic process GO:0044042 62 38 0,000 0,1655403 0,18751881 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,16950744 0,19192231 ! mammary gland development GO:0030879 86 39 0,000 0,16950744 0,19183203 ! learning GO:0007612 77 39 0,000 0,16950744 0,19174185 ! ear morphogenesis GO:0042471 60 39 0,000 0,16950744 0,19165174 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,16950744 0,19156172 ! segmentation GO:0035282 67 39 0,000 0,16950744 0,19147179 ! ion transmembrane transport GO:0034220 66 39 0,000 0,16950744 0,19138194 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,16950744 0,19129217 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,16950744 0,19120249 ! RNA modification GO:0009451 57 39 0,000 0,16950744 0,19111289 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,16950744 0,19102337 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,17345586 0,19538146 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,17345586 0,19529003 ! feeding behavior GO:0007631 59 40 0,000 0,17345586 0,19519869 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,17345586 0,19510743 ! maintenance of protein location GO:0045185 91 40 0,000 0,17345586 0,19501626 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,17738563 0,19934135 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,17738563 0,19924829 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,17738563 0,19915531 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,17738563 0,19906242 ! gliogenesis GO:0042063 88 41 0,000 0,17738563 0,19896962 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,17738563 0,1988769 ! female gamete generation GO:0007292 61 41 0,000 0,17738563 0,19878427 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,18129685 0,20307273 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,18129685 0,20297823 ! regulation of tube size GO:0035150 71 42 0,000 0,18129685 0,20288382 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,18129685 0,2027895 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,18129685 0,20269527 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,18129685 0,20260113 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,18129685 0,20250707 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,1851896 0,20675925 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,1851896 0,20666335 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,1851896 0,20656754 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,1851896 0,20647182 ! glucose transport GO:0015758 65 43 0,000 0,1851896 0,20637619 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,1851896 0,20628064 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,1851896 0,20618519 ! striated muscle contraction GO:0006941 77 43 0,000 0,1851896 0,20608982 ! phagocytosis GO:0006909 90 43 0,000 0,1851896 0,20599454 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,1851896 0,20589935 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,18906398 0,2101099 ! hexose transport GO:0008645 67 44 0,000 0,18906398 0,21001289 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 0,000 0,18906398 0,20991598 ! biopolymer methylation GO:0043414 84 44 0,000 0,18906398 0,20981916 ! B cell differentiation GO:0030183 107 44 0,000 0,18906398 0,20972242 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,18906398 0,20962577 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,18906398 0,20952922 ! developmental growth GO:0048589 82 44 0,000 0,18906398 0,20943275 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,19292006 0,21360592 ! glycolysis GO:0006096 65 45 0,000 0,19292006 0,21350766 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,19292006 0,2134095 ! leukocyte migration GO:0050900 68 45 0,000 0,19292006 0,21331142 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,19292006 0,21321344 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,19292006 0,21311554 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,19292006 0,21301774 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,19292006 0,21292002 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,19292006 0,2128224 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,19292006 0,21272486 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,19292006 0,21262742 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,19675793 0,21675804 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,19675793 0,21665884 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,19675793 0,21655973 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,19675793 0,21646071 ! pigmentation GO:0043473 100 46 0,000 0,19675793 0,21636178 ! response to insulin stimulus GO:0032868 95 46 0,000 0,19675793 0,21626294 ! positive regulation of defense response GO:0031349 76 47 0,000 0,20057767 0,22036068 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,20057767 0,2202601 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,20057767 0,22015962 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,20057767 0,22005923 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,20057767 0,21995892 ! JNK cascade GO:0007254 91 47 0,000 0,20057767 0,21985872 ! methylation GO:0032259 90 47 0,000 0,20057767 0,2197586 ! protein homooligomerization GO:0051260 76 47 0,000 0,20057767 0,21965857 ! mitochondrial transport GO:0006839 82 48 0,000 0,20437938 0,22372011 ! Notch signaling pathway GO:0007219 96 48 0,000 0,20437938 0,22361837 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,20437938 0,22351672 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,20437938 0,22341517 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,20816314 0,22744801 ! regulation of action potential GO:0001508 95 49 0,000 0,20816314 0,22734476 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,20816314 0,22724161 ! regulation of ion transport GO:0043269 77 49 0,000 0,20816314 0,22713855 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,20816314 0,22703559 ! peptide metabolic process GO:0006518 76 49 0,000 0,20816314 0,22693272 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,20816314 0,22682994 ! endocrine system development GO:0035270 104 49 0,000 0,20816314 0,22672726 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,20816314 0,22662466 GO:0019724|B cell mediated immunity, ! neuromuscular process GO:0050905 99 50 0,000 0,21192902 0,23062019 ! inner ear development GO:0048839 79 50 0,000 0,21192902 0,23051593 ! histone modification GO:0016570 91 50 0,000 0,21192902 0,23041176 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,21192902 0,23030769 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,21192902 0,23020372 ! positive regulation of binding GO:0051099 78 51 0,000 0,21567712 0,2341693 ! viral infectious cycle GO:0019058 99 51 0,000 0,21567712 0,23406367 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,21567712 0,23395814 ! excretion GO:0007588 83 51 0,000 0,21567712 0,23385271 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,21567712 0,23374737 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,21567712 0,23364213 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,21567712 0,23353698 ! regulation of cell shape GO:0008360 125 51 0,000 0,21567712 0,23343192 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,21940752 0,23736264 ! membrane fusion GO:0006944 110 52 0,000 0,21940752 0,23725596 ! positive regulation of growth GO:0045927 90 52 0,000 0,21940752 0,23714937 ! covalent chromatin modification GO:0016569 101 52 0,000 0,21940752 0,23704288 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,21940752 0,23693649 ! amino acid activation GO:0043038 92 52 0,000 0,21940752 0,23683019 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 0,000 0,21940752 0,23672399 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,2231203 0,2406219 ! RNA catabolic process GO:0006401 93 53 0,000 0,2231203 0,24051409 ! regulation of translational initiation GO:0006446 82 53 0,000 0,2231203 0,24040638 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,2231203 0,24029877 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,2231203 0,24019125 ! cell maturation GO:0048469 100 53 0,000 0,2231203 0,24008383 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,2231203 0,23997651 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,22681555 0,24384191 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,22681555 0,24373301 ! cell recognition GO:0008037 85 54 0,000 0,22681555 0,2436242 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,22681555 0,24351549 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,22681555 0,24340687 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,22681555 0,24329835 ! chloride transport GO:0006821 90 55 0,000 0,23049334 0,24713323 ! glucose catabolic process GO:0006007 82 55 0,000 0,23049334 0,24702315 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,23049334 0,24691316 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,23049334 0,24680328 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,23049334 0,24669349 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,23049334 0,2465838 ! gastrulation GO:0007369 112 55 0,000 0,23049334 0,24647421 ! heart morphogenesis GO:0003007 97 55 0,000 0,23049334 0,24636471 ! RNA elongation GO:0006354 79 55 0,000 0,23049334 0,24625531 ! nuclear export GO:0051168 97 55 0,000 0,23049334 0,24614601 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,23049334 0,24603681 ! sensory perception of smell GO:0007608 80 56 0,000 0,23415375 0,24983323 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,23415375 0,24972249 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,23415375 0,24961184 ! proton transport GO:0015992 94 56 0,000 0,23415375 0,2495013 ! muscle fiber development GO:0048747 112 57 0,000 0,23779688 0,25327105 ! lipid modification GO:0030258 97 57 0,000 0,23779688 0,25315898 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,23779688 0,25304701 ! hydrogen transport GO:0006818 97 58 0,000 0,2414228 0,25679189 ! regulation of endocytosis GO:0030100 91 58 0,000 0,2414228 0,25667841 ! adult behavior GO:0030534 99 58 0,000 0,2414228 0,25656504 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,2414228 0,25645176 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,24503158 0,26017034 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,24503158 0,26005557 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,24503158 0,25994091 ! establishment of organelle localization GO:0051656 109 59 0,000 0,24503158 0,25982635 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,24862332 0,26351882 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,24862332 0,26340278 ! regulation of heart contraction GO:0008016 110 60 0,000 0,24862332 0,26328684 ! camera-type eye development GO:0043010 116 60 0,000 0,24862332 0,26317101 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,24862332 0,26305528 ! kidney development GO:0001822 122 60 0,000 0,24862332 0,26293965 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,25219809 0,26660308 ! mesoderm development GO:0007498 119 61 0,000 0,25219809 0,26648599 ! tRNA processing GO:0008033 89 61 0,000 0,25219809 0,26636901 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,25219809 0,26625213 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,25219809 0,26613535 ! ear development GO:0043583 103 62 0,000 0,25575597 0,26977153 ! viral reproductive process GO:0022415 126 62 0,000 0,25575597 0,26965332 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,25575597 0,2695352 ! gonad development GO:0008406 98 62 0,000 0,25575597 0,26941719 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,25575597 0,26929929 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,25929704 0,27290844 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,25929704 0,27278911 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,25929704 0,27266988 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,26282138 0,27625524 ! cell redox homeostasis GO:0045454 102 64 0,000 0,26282138 0,27613461 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,26282138 0,27601408 ! single fertilization GO:0007338 75 64 0,000 0,26282138 0,27589365 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,26632907 0,27945388 ! germ cell development GO:0007281 118 65 0,000 0,26632907 0,27933206 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,26982019 0,28287031 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,26982019 0,28274711 ! secondary metabolic process GO:0019748 116 66 0,000 0,26982019 0,28262402 ! cell projection assembly GO:0030031 120 66 0,000 0,26982019 0,28250103 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,2732948 0,28601448 ! lung development GO:0030324 144 67 0,000 0,2732948 0,28589013 ! chromosome segregation GO:0007059 113 67 0,000 0,2732948 0,28576588 ! hexose catabolic process GO:0019320 104 67 0,000 0,2732948 0,28564174 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,2732948 0,28551771 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,2732948 0,28539379 ! adaptive immune response GO:0002250 119 67 0,000 0,2732948 0,28526998 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! amino acid transport GO:0006865 125 68 0,000 0,276753 0,28875443 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,276753 0,28862927 ! viral reproduction GO:0016032 134 68 0,000 0,276753 0,28850421 ! regulation of lipase activity GO:0060191 130 68 0,000 0,276753 0,28837926 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,28019486 0,29183932 ! urogenital system development GO:0001655 137 69 0,000 0,28019486 0,29171303 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,28019486 0,29158686 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,28019486 0,2914608 ! antigen processing and presentation GO:0019882 104 69 0,000 0,28019486 0,29133484 ! respiratory tube development GO:0030323 150 70 0,000 0,28362045 0,29476924 ! amine catabolic process GO:0009310 117 71 0,000 0,28702985 0,29818386 ! reproductive structure development GO:0048608 113 71 0,000 0,28702985 0,29805516 ! B cell activation GO:0042113 160 71 0,000 0,28702985 0,29792658 ! regulation of immune effector process GO:0002697 137 71 0,000 0,28702985 0,29779811 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,29042314 0,30118882 ! carbohydrate transport GO:0008643 110 72 0,000 0,29042314 0,30105905 ! respiratory system development GO:0060541 153 72 0,000 0,29042314 0,3009294 ! learning or memory GO:0007611 147 73 0,000 0,29380039 0,30429777 ! regulation of blood pressure GO:0008217 125 73 0,000 0,29380039 0,30416684 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,29380039 0,30403601 ! fertilization GO:0009566 90 73 0,000 0,29380039 0,3039053 ! transition metal ion transport GO:0000041 126 74 0,000 0,29716167 0,3072501 ! neurotransmitter transport GO:0006836 123 74 0,000 0,29716167 0,30711812 ! exocytosis GO:0006887 133 74 0,000 0,29716167 0,30698625 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,29716167 0,3068545 ! eye development GO:0001654 143 74 0,000 0,29716167 0,30672286 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,30050708 0,31004289 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,30050708 0,30991 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,30050708 0,30977722 ! rhythmic process GO:0048511 128 75 0,000 0,30050708 0,30964455 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,30383666 0,31294136 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,30383666 0,31280745 ! defense response to bacterium GO:0042742 89 76 0,000 0,30383666 0,31267366 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,30383666 0,31253998 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,30383666 0,31240642 ! regulation of catabolic process GO:0009894 161 76 0,000 0,30383666 0,31227297 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,30715051 0,31554404 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,30715051 0,31540936 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,3104487 0,31866022 ! protein oligomerization GO:0051259 139 78 0,000 0,3104487 0,31852434 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,31373129 0,32175511 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,31373129 0,32161802 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,31373129 0,32148104 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,31373129 0,32134418 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,31699837 0,32455237 ! muscle cell differentiation GO:0042692 159 80 0,000 0,31699837 0,32441432 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,31699837 0,32427639 ! protein import into nucleus GO:0006606 158 80 0,000 0,31699837 0,32413858 ! inorganic anion transport GO:0015698 138 80 0,000 0,31699837 0,32400088 ! digestion GO:0007586 112 81 0,000 0,32025 0,32718535 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,32025 0,32704648 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,32025 0,32690772 ! nuclear import GO:0051170 161 81 0,000 0,32025 0,32676908 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,32025 0,32663056 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,32348626 0,3297915 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,32348626 0,32965181 ! response to drug GO:0042493 143 82 0,000 0,32348626 0,32951225 ! response to nutrient GO:0007584 125 82 0,000 0,32348626 0,3293728 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,32348626 0,32923347 ! regulation of lyase activity GO:0051339 160 83 0,000 0,32670721 0,33237106 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,32991294 0,33549051 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,32991294 0,33534877 ! nucleosome assembly GO:0006334 122 85 0,000 0,33310352 0,33844893 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,33310352 0,33830606 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,33310352 0,33816332 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,336279 0,34124305 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,336279 0,34109919 ! chromatin assembly GO:0031497 124 86 0,000 0,336279 0,34095545 ! amine transport GO:0015837 155 86 0,000 0,336279 0,34081183 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,33943947 0,34387005 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,33943947 0,34372532 ! protein localization in nucleus GO:0034504 176 87 0,000 0,33943947 0,34358072 ! cellular respiration GO:0045333 135 88 0,000 0,342585 0,3466188 ! gland development GO:0048732 206 88 0,000 0,342585 0,3464731 ! regulation of neurological system process GO:0031644 148 88 0,000 0,342585 0,34632752 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,342585 0,34618207 ! cellular defense response GO:0006968 114 89 0,000 0,34571565 0,34919893 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,34571565 0,34905239 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,3488315 0,35205058 ! sex differentiation GO:0007548 145 90 0,000 0,3488315 0,35190297 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,3488315 0,35175548 ! sterol metabolic process GO:0016125 152 91 0,000 0,35193261 0,35473392 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,35193261 0,35458537 ! regulation of defense response GO:0031347 149 92 0,000 0,35501906 0,35754535 ! nucleosome organization GO:0034728 138 92 0,000 0,35501906 0,35739575 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,35501906 0,35724628 ! vitamin metabolic process GO:0006766 139 92 0,000 0,35501906 0,35709693 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,35809091 0,36003624 ! regulation of membrane potential GO:0042391 164 93 0,000 0,35809091 0,35988585 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,36114823 0,36280694 ! transcription initiation GO:0006352 153 94 0,000 0,36114823 0,36265552 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,36721956 0,36859835 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,36721956 0,36844464 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,3702337 0,371314 ! protein ubiquitination GO:0016567 217 97 0,000 0,3702337 0,37115928 ! response to virus GO:0009615 160 98 0,000 0,37323358 0,37401083 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,37323358 0,37385512 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,37323358 0,37369954 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,37621928 0,37653228 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,37621928 0,37637571 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,37621928 0,37621928 GO:0060538|skeletal muscle organ development,