pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-pos-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/55-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 2,649E-05 0,06092342 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 1,000 2,649E-05 0,03046171 ! wound healing, spreading of epidermal cells GO:0035313 10 6 1,000 3,969E-05 0,03043035 ! interaction with symbiont GO:0051702 8 6 1,000 3,969E-05 0,02282276 ! negative regulation of JAK-STAT cascade GO:0046426 15 7 1,000 5,551E-05 0,02553518 ! integrin-mediated signaling pathway GO:0007229 81 49 2,000 7,183E-05 0,02753571 ! mitochondrion localization GO:0051646 12 8 1,000 7,394E-05 0,02429419 ! cell-matrix adhesion GO:0007160 114 61 2,000 1,385E-04 0,03980585 ! dicarboxylic acid transport GO:0006835 22 12 1,000 1,736E-04 0,04435629 ! neutral amino acid transport GO:0015804 19 12 1,000 1,736E-04 0,03992066 ! cell-substrate adhesion GO:0031589 121 66 2,000 1,751E-04 0,03660402 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 1,000 2,049E-04 0,03927535 ! heterophilic cell adhesion GO:0007157 29 14 1,000 2,388E-04 0,04225302 ! cellular response to starvation GO:0009267 21 14 1,000 2,388E-04 0,03923494 ! cell killing GO:0001906 20 14 1,000 2,388E-04 0,03661928 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 2,753E-04 0,03957146 ! memory GO:0007613 25 17 1,000 3,558E-04 0,04814031 ! inactivation of MAPK activity GO:0000188 27 17 1,000 3,558E-04 0,04546584 ! cell-substrate junction assembly GO:0007044 39 17 1,000 3,558E-04 0,04307291 ! cellular response to nutrient levels GO:0031669 27 18 1,000 3,999E-04 0,04598683 ! response to starvation GO:0042594 30 19 1,000 4,465E-04 0,04889923 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 5,472E-04 0,05720424 ! leukocyte adhesion GO:0007159 38 22 1,000 6,013E-04 0,06012694 ! interaction with host GO:0051701 37 23 1,000 6,579E-04 0,06304455 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 6,579E-04 0,06052277 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 7,785E-04 0,06886411 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of chromosome organization GO:0033044 35 25 1,000 7,785E-04 0,06631359 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 8,425E-04 0,06920282 ! negative regulation of protein kinase cascade GO:0010741 51 26 1,000 8,425E-04 0,06681652 ! negative regulation of protein modification process GO:0031400 50 26 1,000 8,425E-04 0,0645893 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 1,000 9,778E-04 0,0725497 ! cell junction assembly GO:0034329 56 28 1,000 9,778E-04 0,07028252 ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 9,778E-04 0,06815274 ! ceramide metabolic process GO:0006672 43 30 1,000 1,123E-03 0,07596665 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 1,278E-03 0,08397183 ! cell junction organization GO:0034330 63 33 1,000 1,359E-03 0,08681707 ! sphingoid metabolic process GO:0046519 47 33 1,000 1,359E-03 0,08447066 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 1,442E-03 0,08729849 ! regulation of Rab protein signal transduction GO:0032483 52 35 1,000 1,528E-03 0,09012258 GO:0032313|regulation of Rab GTPase activity, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 1,000 1,707E-03 0,09815292 ! pigmentation GO:0043473 74 38 1,000 1,8E-03 0,10097511 ! maintenance of location in cell GO:0051651 69 38 1,000 1,8E-03 0,09857094 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 2,196E-03 0,11743394 ! regulation of DNA replication GO:0006275 75 48 1,000 2,859E-03 0,14943097 ! maintenance of location GO:0051235 84 49 1,000 2,977E-03 0,15217151 ! sphingolipid metabolic process GO:0006665 72 52 1,000 3,347E-03 0,16733528 ! skeletal system morphogenesis GO:0048705 78 53 1,000 3,474E-03 0,17002301 ! amino acid transport GO:0006865 84 54 1,000 3,604E-03 0,17270674 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 4,008E-03 0,18810986 ! membrane lipid metabolic process GO:0006643 79 57 1,000 4,008E-03 0,18434767 ! negative regulation of kinase activity GO:0033673 100 58 1,000 4,146E-03 0,18699593 ! negative regulation of transferase activity GO:0051348 105 61 1,000 4,576E-03 0,20241447 ! negative regulation of cell growth GO:0030308 106 62 1,000 4,724E-03 0,20500495 ! organelle localization GO:0051640 96 62 1,000 4,724E-03 0,20120856 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 4,874E-03 0,20381828 ! negative regulation of cell size GO:0045792 108 64 1,000 5,026E-03 0,2064244 ! learning or memory GO:0007611 123 68 1,000 5,656E-03 0,22822203 ! regulation of Ras GTPase activity GO:0032318 110 68 1,000 5,656E-03 0,22428717 ! amine transport GO:0015837 101 70 1,000 5,984E-03 0,23326745 ! negative regulation of organelle organization GO:0010639 115 72 1,000 6,32E-03 0,24227528 ! negative regulation of growth GO:0045926 123 75 1,000 6,841E-03 0,25792812 ! regulation of GTPase activity GO:0043087 129 80 1,000 7,75E-03 0,2875004 ! regulation of cell cycle process GO:0010564 122 81 1,000 7,938E-03 0,28980318 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 8,268E-03 0,29712105 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 8,268E-03 0,29254995 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 8,268E-03 0,28811738 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 8,268E-03 0,28381712 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 8,268E-03 0,27964334 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 8,268E-03 0,27559054 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 8,268E-03 0,27165353 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 8,268E-03 0,26782742 ! sleep GO:0030431 11 5 0,000 8,268E-03 0,2641076 ! negative regulation of bone resorption GO:0045779 10 5 0,000 8,268E-03 0,26048968 ! nucleotide-sugar transport GO:0015780 8 5 0,000 8,268E-03 0,25696955 ! regulation of interferon-beta production GO:0032648 5 5 0,000 8,268E-03 0,25354329 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 8,268E-03 0,2502072 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 8,268E-03 0,24695775 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 8,268E-03 0,24379163 ! tongue development GO:0043586 6 5 0,000 8,268E-03 0,24070566 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 8,268E-03 0,23769684 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 8,268E-03 0,23476231 ! cobalt ion transport GO:0006824 9 5 0,000 8,268E-03 0,23189935 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 8,268E-03 0,22910539 ! SMAD protein complex assembly GO:0007183 9 5 0,000 8,268E-03 0,22637794 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 8,268E-03 0,22371467 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 8,268E-03 0,22111334 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 8,268E-03 0,2185718 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 8,268E-03 0,21608803 ! embryonic camera-type eye development GO:0031076 8 5 0,000 8,268E-03 0,21366008 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 8,268E-03 0,21128608 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 8,268E-03 0,20896425 ! adaptation of signaling pathway GO:0022401 7 5 0,000 8,268E-03 0,2066929 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 8,268E-03 0,2044704 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 8,268E-03 0,20229518 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 8,268E-03 0,20016576 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 8,268E-03 0,1980807 ! positive regulation of histone modification GO:0031058 5 5 0,000 8,268E-03 0,19603863 ! malate metabolic process GO:0006108 7 5 0,000 8,268E-03 0,19403823 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 8,268E-03 0,19207825 ! behavioral response to pain GO:0048266 7 5 0,000 8,268E-03 0,19015747 ! clathrin coat assembly GO:0048268 11 5 0,000 8,268E-03 0,18827472 ! phototransduction, visible light GO:0007603 6 5 0,000 8,268E-03 0,18642889 ! regulation of dopamine uptake GO:0051584 9 5 0,000 8,268E-03 0,1846189 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 8,268E-03 0,18284372 ! mating behavior GO:0007617 6 5 0,000 8,268E-03 0,18110235 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 8,268E-03 0,17939384 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 8,268E-03 0,17771726 ! rhythmic behavior GO:0007622 12 5 0,000 8,268E-03 0,17607173 ! copulation GO:0007620 7 5 0,000 8,268E-03 0,17445639 ! glial cell fate commitment GO:0021781 12 5 0,000 8,268E-03 0,17287043 ! protein maturation by protein folding GO:0022417 12 5 0,000 8,268E-03 0,17131304 ! embryonic hemopoiesis GO:0035162 10 5 0,000 8,268E-03 0,16978346 ! regulation of potassium ion transport GO:0043266 9 5 0,000 8,268E-03 0,16828095 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 8,268E-03 0,1668048 ! apoptotic cell clearance GO:0043277 13 5 0,000 8,268E-03 0,16535432 ! lipoprotein particle clearance GO:0034381 9 5 0,000 8,268E-03 0,16392885 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 8,268E-03 0,16252775 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 8,268E-03 0,1611504 ! response to protozoan GO:0001562 9 5 0,000 8,268E-03 0,15979619 ! positive regulation of glycolysis GO:0045821 11 5 0,000 8,268E-03 0,15846456 ! lymph vessel development GO:0001945 7 5 0,000 8,268E-03 0,15715493 ! endochondral ossification GO:0001958 12 5 0,000 8,268E-03 0,15586678 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 8,268E-03 0,15459957 ! parathyroid gland development GO:0060017 8 5 0,000 8,268E-03 0,1533528 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 8,268E-03 0,15212598 ! anagen GO:0042640 6 5 0,000 8,268E-03 0,15091863 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 8,268E-03 0,14973029 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 8,268E-03 0,14856052 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 8,268E-03 0,14740889 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 8,268E-03 0,14627498 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 8,268E-03 0,14515837 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 8,268E-03 0,14405869 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 8,268E-03 0,14297554 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 8,268E-03 0,14190856 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 8,268E-03 0,14085739 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 8,268E-03 0,13982167 ! cardiac muscle fiber development GO:0048739 7 5 0,000 8,268E-03 0,13880107 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 8,268E-03 0,13779527 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 8,268E-03 0,13680394 ! neutrophil mediated immunity GO:0002446 6 5 0,000 8,268E-03 0,13582676 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 8,268E-03 0,13486345 ! ovulation GO:0030728 6 5 0,000 8,268E-03 0,13391371 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 8,268E-03 0,13297725 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 8,268E-03 0,1320538 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 8,268E-03 0,13114308 ! response to pH GO:0009268 9 5 0,000 8,268E-03 0,13024484 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 8,268E-03 0,12935882 ! proline biosynthetic process GO:0006561 6 5 0,000 8,268E-03 0,12848478 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 8,268E-03 0,12762246 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 8,268E-03 0,12677165 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 8,268E-03 0,1259321 ! polyol catabolic process GO:0046174 7 5 0,000 8,268E-03 0,1251036 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 8,268E-03 0,12428593 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 8,268E-03 0,12347888 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 8,268E-03 0,12268224 ! sister chromatid cohesion GO:0007062 9 5 0,000 8,268E-03 0,12189581 ! nerve growth factor processing GO:0032455 7 5 0,000 8,268E-03 0,12111941 ! urea metabolic process GO:0019627 6 5 0,000 8,268E-03 0,12035283 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 8,268E-03 0,11959589 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 8,268E-03 0,11884842 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 8,268E-03 0,11811023 ! neutrophil activation GO:0042119 5 5 0,000 8,268E-03 0,11738115 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 8,268E-03 0,11666102 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 8,268E-03 0,11594968 ! response to food GO:0032094 5 5 0,000 8,268E-03 0,11524695 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 8,268E-03 0,11455269 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 8,268E-03 0,11386675 ! paraxial mesoderm development GO:0048339 9 5 0,000 8,268E-03 0,11318897 ! forebrain neuron development GO:0021884 7 5 0,000 8,268E-03 0,11251921 ! melanosome organization GO:0032438 7 5 0,000 8,268E-03 0,11185734 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 8,268E-03 0,1112032 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 8,268E-03 0,11055667 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 8,268E-03 0,10991761 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 8,268E-03 0,1092859 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 8,268E-03 0,10866141 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 8,268E-03 0,10804402 ! nucleoside transport GO:0015858 6 5 0,000 8,268E-03 0,1074336 ! nucleoside salvage GO:0043174 7 5 0,000 8,268E-03 0,10683004 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 8,268E-03 0,10623322 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 8,268E-03 0,10564304 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 8,268E-03 0,10505938 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 8,268E-03 0,10448213 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 8,268E-03 0,10391119 ! early endosome to late endosome transport GO:0045022 11 5 0,000 8,268E-03 0,10334645 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 8,268E-03 0,10278782 ! depyrimidination GO:0045008 8 5 0,000 8,268E-03 0,1022352 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 8,268E-03 0,10168849 ! 5S class rRNA transcription GO:0042791 8 5 0,000 8,268E-03 0,10114759 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 8,268E-03 0,10061242 ! regulation of centrosome cycle GO:0046605 7 5 0,000 8,268E-03 0,10008288 ! neuronal ion channel clustering GO:0045161 7 5 0,000 8,268E-03 0,09955888 ! sodium ion homeostasis GO:0055078 6 5 0,000 8,268E-03 0,09904035 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 8,268E-03 0,09852719 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 8,268E-03 0,09801931 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 8,268E-03 0,09751665 ! monocyte differentiation GO:0030224 8 5 0,000 8,268E-03 0,09701912 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 8,268E-03 0,09652663 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 8,268E-03 0,09603913 ! centrosome duplication GO:0051298 5 5 0,000 8,268E-03 0,09555652 ! response to UV-C GO:0010225 6 5 0,000 8,268E-03 0,09507873 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 8,268E-03 0,09460571 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 8,268E-03 0,09413736 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 8,268E-03 0,09367363 ! regulation of dendrite development GO:0050773 12 5 0,000 8,268E-03 0,09321445 ! peptidyl-arginine modification GO:0018195 7 5 0,000 8,268E-03 0,09275974 ! positive regulation of organ growth GO:0046622 6 5 0,000 8,268E-03 0,09230945 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 8,268E-03 0,09186351 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 8,268E-03 0,09142186 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 8,268E-03 0,09098444 ! regulation of dopamine secretion GO:0014059 12 5 0,000 8,268E-03 0,09055118 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 8,268E-03 0,09012202 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 8,268E-03 0,08969692 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 8,268E-03 0,08927581 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 8,268E-03 0,08885863 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 8,268E-03 0,08844533 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 8,268E-03 0,08803587 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 8,268E-03 0,08763017 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 8,268E-03 0,0872282 ! neural tube patterning GO:0021532 6 5 0,000 8,268E-03 0,08682989 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 8,268E-03 0,08643521 ! histone demethylation GO:0016577 9 5 0,000 8,268E-03 0,0860441 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 8,268E-03 0,08565652 ! regulation of sterol transport GO:0032371 7 5 0,000 8,268E-03 0,08527241 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 8,268E-03 0,08489173 ! enteric nervous system development GO:0048484 8 5 0,000 8,268E-03 0,08451443 ! establishment of planar polarity GO:0001736 6 5 0,000 8,268E-03 0,08414047 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 8,268E-03 0,08376981 ! muscle cell proliferation GO:0033002 8 5 0,000 8,268E-03 0,0834024 ! transcription termination GO:0006353 8 5 0,000 8,268E-03 0,0830382 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 8,268E-03 0,08267716 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 8,268E-03 0,08231925 ! regulation of respiratory burst GO:0060263 8 5 0,000 8,268E-03 0,08196443 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 8,268E-03 0,08161265 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 8,268E-03 0,08126388 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 8,268E-03 0,08091807 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 8,268E-03 0,0805752 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 8,268E-03 0,08023522 ! apical protein localization GO:0045176 6 5 0,000 8,268E-03 0,0798981 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 8,268E-03 0,07956379 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 8,268E-03 0,07923228 ! galactolipid metabolic process GO:0019374 7 5 0,000 8,268E-03 0,07890351 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 8,268E-03 0,07857747 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 8,268E-03 0,0782541 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 8,268E-03 0,07793339 ! triglyceride catabolic process GO:0019433 6 5 0,000 8,268E-03 0,07761529 ! glial cell migration GO:0008347 10 5 0,000 8,268E-03 0,07729978 ! determination of adult lifespan GO:0008340 8 5 0,000 8,268E-03 0,07698683 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 8,268E-03 0,0766764 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 8,268E-03 0,07636846 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 8,268E-03 0,07606299 ! somatic stem cell maintenance GO:0035019 13 5 0,000 8,268E-03 0,07575995 ! cerebellar cortex formation GO:0021697 6 5 0,000 8,268E-03 0,07545931 ! neural plate development GO:0001840 6 5 0,000 8,268E-03 0,07516106 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 8,268E-03 0,07486515 ! regulation of sensory perception GO:0051931 6 5 0,000 8,268E-03 0,07457156 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 8,268E-03 0,07428026 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 8,268E-03 0,07399123 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 8,268E-03 0,07370445 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 8,268E-03 0,07341987 ! sensory cilium assembly GO:0035058 6 5 0,000 8,268E-03 0,07313749 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 8,268E-03 0,07285727 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 8,268E-03 0,07257919 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 8,268E-03 0,07230322 ! spindle assembly GO:0051225 5 5 0,000 8,268E-03 0,07202934 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 8,268E-03 0,07175754 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 8,268E-03 0,07148777 ! protein amino acid prenylation GO:0018346 9 5 0,000 8,268E-03 0,07122003 ! organ regeneration GO:0031100 7 5 0,000 8,268E-03 0,07095428 ! NAD biosynthetic process GO:0009435 7 5 0,000 8,268E-03 0,07069051 ! carnitine metabolic process GO:0009437 5 5 0,000 8,268E-03 0,07042869 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 8,268E-03 0,07016881 ! cellular anion homeostasis GO:0030002 6 5 0,000 8,268E-03 0,06991083 GO:0055081|anion homeostasis, ! regulation of cell adhesion GO:0030155 159 83 1,000 8,32E-03 0,0700986 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 8,711E-03 0,07312051 ! tRNA transcription GO:0009304 11 6 0,000 9,913E-03 0,08291141 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 9,913E-03 0,08261101 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 9,913E-03 0,08231277 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 9,913E-03 0,08201668 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 9,913E-03 0,08172272 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 9,913E-03 0,08143085 ! regulation of helicase activity GO:0051095 11 6 0,000 9,913E-03 0,08114106 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 9,913E-03 0,08085333 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 9,913E-03 0,08056763 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 9,913E-03 0,08028394 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 9,913E-03 0,08000224 ! positive regulation of axon extension GO:0045773 8 6 0,000 9,913E-03 0,07972251 ! prostate gland development GO:0030850 9 6 0,000 9,913E-03 0,07944473 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 9,913E-03 0,07916888 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 9,913E-03 0,07889494 ! forebrain neuron differentiation GO:0021879 9 6 0,000 9,913E-03 0,07862289 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 9,913E-03 0,07835271 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 9,913E-03 0,07808438 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 9,913E-03 0,07781788 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 9,913E-03 0,07755319 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 9,913E-03 0,0772903 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 9,913E-03 0,07702918 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 9,913E-03 0,07676983 ! neuron adhesion GO:0007158 9 6 0,000 9,913E-03 0,07651221 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 9,913E-03 0,07625632 ! establishment of tissue polarity GO:0007164 7 6 0,000 9,913E-03 0,07600213 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 9,913E-03 0,07574963 ! signal peptide processing GO:0006465 8 6 0,000 9,913E-03 0,0754988 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 9,913E-03 0,07524963 ! mRNA stabilization GO:0048255 15 6 0,000 9,913E-03 0,0750021 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 9,913E-03 0,07475619 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 9,913E-03 0,07451189 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 9,913E-03 0,07426918 ! opsonization GO:0008228 8 6 0,000 9,913E-03 0,07402805 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 9,913E-03 0,07378847 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 9,913E-03 0,07355045 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 9,913E-03 0,07331395 ! protein amino acid dealkylation GO:0008214 11 6 0,000 9,913E-03 0,07307897 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 9,913E-03 0,07284549 ! photoreceptor cell development GO:0042461 10 6 0,000 9,913E-03 0,0726135 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 9,913E-03 0,07238298 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 9,913E-03 0,07215392 ! mechanosensory behavior GO:0007638 8 6 0,000 9,913E-03 0,0719263 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 9,913E-03 0,07170012 ! negative regulation of endocytosis GO:0045806 8 6 0,000 9,913E-03 0,07147535 ! response to interferon-gamma GO:0034341 12 6 0,000 9,913E-03 0,07125199 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 9,913E-03 0,07103003 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 9,913E-03 0,07080944 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 9,913E-03 0,07059021 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 9,913E-03 0,07037234 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 9,913E-03 0,07015581 ! cGMP-mediated signaling GO:0019934 10 6 0,000 9,913E-03 0,06994061 ! activation of MAPKKK activity GO:0000185 10 6 0,000 9,913E-03 0,06972672 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 9,913E-03 0,06951414 ! thymic T cell selection GO:0045061 12 6 0,000 9,913E-03 0,06930285 ! protein lipoylation GO:0009249 10 6 0,000 9,913E-03 0,06909284 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 9,913E-03 0,0688841 ! pigment granule organization GO:0048753 11 6 0,000 9,913E-03 0,06867662 ! drug transport GO:0015893 6 6 0,000 9,913E-03 0,06847038 ! cysteine metabolic process GO:0006534 7 6 0,000 9,913E-03 0,06826538 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 9,913E-03 0,06806161 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 9,913E-03 0,06785904 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 9,913E-03 0,06765768 ! histidine metabolic process GO:0006547 6 6 0,000 9,913E-03 0,06745751 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 9,913E-03 0,06725852 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 9,913E-03 0,0670607 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 9,913E-03 0,06686404 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 9,913E-03 0,06666853 ! adenohypophysis development GO:0021984 10 6 0,000 9,913E-03 0,06647416 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 9,913E-03 0,06628092 ! hyperosmotic response GO:0006972 8 6 0,000 9,913E-03 0,06608881 ! microtubule nucleation GO:0007020 10 6 0,000 9,913E-03 0,0658978 ! ER overload response GO:0006983 7 6 0,000 9,913E-03 0,06570789 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 9,913E-03 0,06551908 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 9,913E-03 0,06533134 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 9,913E-03 0,06514468 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 9,913E-03 0,06495908 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 9,913E-03 0,06477454 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 9,913E-03 0,06459104 ! response to dietary excess GO:0002021 7 6 0,000 9,913E-03 0,06440858 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 9,913E-03 0,06422715 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 9,913E-03 0,06404674 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 9,913E-03 0,06386733 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 9,913E-03 0,06368893 ! glycerol ether catabolic process GO:0044269 8 6 0,000 9,913E-03 0,06351153 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 9,913E-03 0,06333511 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 9,913E-03 0,06315966 ! neuron apoptosis GO:0051402 8 6 0,000 9,913E-03 0,06298519 ! organic alcohol transport GO:0015850 9 6 0,000 9,913E-03 0,06281168 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 9,913E-03 0,06263912 ! T cell mediated immunity GO:0002456 12 6 0,000 9,913E-03 0,0624675 ! male sex determination GO:0030238 9 6 0,000 9,913E-03 0,06229683 ! carnitine transport GO:0015879 8 6 0,000 9,913E-03 0,06212708 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 9,913E-03 0,06195826 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 9,913E-03 0,06179035 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 9,913E-03 0,06162335 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 9,913E-03 0,06145725 ! positive regulation of exocytosis GO:0045921 6 6 0,000 9,913E-03 0,06129204 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 9,913E-03 0,06112772 ! parturition GO:0007567 12 6 0,000 9,913E-03 0,06096427 ! negative regulation of translational initiation GO:0045947 7 6 0,000 9,913E-03 0,0608017 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 9,913E-03 0,06064 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 9,913E-03 0,06047915 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 9,913E-03 0,06031915 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 9,913E-03 0,06016 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 9,913E-03 0,06000168 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 9,913E-03 0,05984419 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 9,913E-03 0,05968753 ! macrophage differentiation GO:0030225 10 6 0,000 9,913E-03 0,05953169 ! astrocyte development GO:0014002 14 6 0,000 9,913E-03 0,05937666 ! hyaluronan metabolic process GO:0030212 6 6 0,000 9,913E-03 0,05922244 ! purine base biosynthetic process GO:0009113 14 6 0,000 9,913E-03 0,05906901 ! anterograde axon cargo transport GO:0008089 8 6 0,000 9,913E-03 0,05891638 ! skeletal muscle contraction GO:0003009 6 6 0,000 9,913E-03 0,05876453 ! eating behavior GO:0042755 6 6 0,000 9,913E-03 0,05861347 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 9,913E-03 0,05846317 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 9,913E-03 0,05831365 ! response to copper ion GO:0046688 9 6 0,000 9,913E-03 0,05816489 ! DNA topological change GO:0006265 8 6 0,000 9,913E-03 0,05801689 ! response to exogenous dsRNA GO:0043330 8 6 0,000 9,913E-03 0,05786964 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 9,913E-03 0,05772313 ! establishment of melanosome localization GO:0032401 9 6 0,000 9,913E-03 0,05757737 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 9,913E-03 0,05743234 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 9,913E-03 0,05728804 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 9,913E-03 0,05714446 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 9,913E-03 0,0570016 ! nucleoside catabolic process GO:0009164 6 6 0,000 9,913E-03 0,05685945 ! gas homeostasis GO:0033483 11 6 0,000 9,913E-03 0,05671801 ! hair follicle maturation GO:0048820 7 6 0,000 9,913E-03 0,05657727 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 9,913E-03 0,05643722 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 9,913E-03 0,05629787 ! Schwann cell development GO:0014044 14 6 0,000 9,913E-03 0,05615921 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 9,913E-03 0,05602122 ! dendrite morphogenesis GO:0048813 9 6 0,000 9,913E-03 0,05588392 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 9,913E-03 0,05574728 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 9,913E-03 0,05561131 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 9,913E-03 0,05547601 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 9,913E-03 0,05534135 ! histone ubiquitination GO:0016574 7 6 0,000 9,913E-03 0,05520736 ! regulation of meiosis GO:0040020 10 6 0,000 9,913E-03 0,05507401 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 9,913E-03 0,0549413 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 9,913E-03 0,05480923 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 9,913E-03 0,05467779 ! regulation of mast cell activation GO:0033003 6 6 0,000 9,913E-03 0,05454698 ! membrane to membrane docking GO:0022614 12 6 0,000 9,913E-03 0,0544168 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 9,913E-03 0,05428723 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 9,913E-03 0,05415829 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 9,913E-03 0,05402995 ! receptor internalization GO:0031623 9 6 0,000 9,913E-03 0,05390222 ! neutrophil homeostasis GO:0001780 6 6 0,000 9,913E-03 0,05377509 ! coenzyme A metabolic process GO:0015936 9 6 0,000 9,913E-03 0,05364856 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 9,913E-03 0,05352262 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 9,913E-03 0,05339728 ! protein deubiquitination GO:0016579 8 6 0,000 9,913E-03 0,05327252 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 9,913E-03 0,05314834 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 9,913E-03 0,05302474 ! peptidyl-histidine modification GO:0018202 9 6 0,000 9,913E-03 0,05290171 ! axonal fasciculation GO:0007413 9 6 0,000 9,913E-03 0,05277926 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 9,913E-03 0,05265736 ! thiamin metabolic process GO:0006772 6 6 0,000 9,913E-03 0,05253603 ! midbrain development GO:0030901 6 6 0,000 9,913E-03 0,05241526 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 9,913E-03 0,05229504 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 9,913E-03 0,05217537 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 9,913E-03 0,05205625 ! progesterone metabolic process GO:0042448 8 6 0,000 9,913E-03 0,05193767 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 9,913E-03 0,05181963 ! glycolipid catabolic process GO:0019377 13 6 0,000 9,913E-03 0,05170213 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 9,913E-03 0,05158515 ! positive regulation of glucose import GO:0046326 6 6 0,000 9,913E-03 0,05146871 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 9,913E-03 0,05135279 ! adult feeding behavior GO:0008343 6 6 0,000 9,913E-03 0,05123739 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 9,913E-03 0,05112251 ! blastocyst growth GO:0001832 15 6 0,000 9,913E-03 0,05100814 ! pigment granule transport GO:0051904 12 6 0,000 9,913E-03 0,05089428 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 9,913E-03 0,05078093 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 9,913E-03 0,05066808 ! catecholamine transport GO:0051937 7 6 0,000 9,913E-03 0,05055574 ! organ or tissue specific immune response GO:0002251 7 6 0,000 9,913E-03 0,05044389 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 9,913E-03 0,05033253 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 9,913E-03 0,05022167 ! negative regulation of B cell activation GO:0050869 9 6 0,000 9,913E-03 0,05011129 ! protein prenylation GO:0018342 10 6 0,000 9,913E-03 0,0500014 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 9,913E-03 0,04989199 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 9,913E-03 0,04978305 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 9,913E-03 0,04967459 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 9,913E-03 0,0495666 ! positive regulation of coagulation GO:0050820 11 6 0,000 9,913E-03 0,04945909 ! DNA recombination GO:0006310 146 92 1,000 0,01014109 0,05048594 ! carboxylic acid transport GO:0046942 147 95 1,000 0,01078389 0,05357006 GO:0015849|organic acid transport, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,01155629 0,05728333 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01155629 0,05716014 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01155629 0,05703748 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01155629 0,05691534 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01155629 0,05679373 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01155629 0,05667263 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01155629 0,05655205 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01155629 0,05643199 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01155629 0,05631243 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01155629 0,05619337 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01155629 0,05607482 ! reproductive behavior GO:0019098 12 7 0,000 0,01155629 0,05595677 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01155629 0,05583921 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01155629 0,05572215 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01155629 0,05560558 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01155629 0,05548949 ! oligopeptide transport GO:0006857 11 7 0,000 0,01155629 0,05537389 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01155629 0,05525876 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01155629 0,05514412 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! RNA methylation GO:0001510 11 7 0,000 0,01155629 0,05502995 ! pericardium development GO:0060039 8 7 0,000 0,01155629 0,05491625 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01155629 0,05480302 ! fibril organization GO:0043206 13 7 0,000 0,01155629 0,05469026 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01155629 0,05457796 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01155629 0,05446612 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01155629 0,05435473 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01155629 0,05424381 ! lipoprotein transport GO:0042953 9 7 0,000 0,01155629 0,05413333 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01155629 0,0540233 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01155629 0,05391372 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01155629 0,05380459 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01155629 0,05369589 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01155629 0,05358763 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01155629 0,05347981 ! chemosensory behavior GO:0007635 9 7 0,000 0,01155629 0,05337242 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01155629 0,05326546 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01155629 0,05315893 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01155629 0,05305282 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01155629 0,05294714 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01155629 0,05284188 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01155629 0,05273703 ! reflex GO:0060004 12 7 0,000 0,01155629 0,0526326 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01155629 0,05252859 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01155629 0,05242498 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01155629 0,05232178 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01155629 0,05221899 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01155629 0,0521166 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01155629 0,05201461 ! spinal cord patterning GO:0021511 7 7 0,000 0,01155629 0,05191302 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01155629 0,05181182 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01155629 0,05171102 ! adrenal gland development GO:0030325 17 7 0,000 0,01155629 0,05161061 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01155629 0,05151059 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01155629 0,05141096 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01155629 0,05131171 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01155629 0,05121284 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01155629 0,05111436 ! endosome organization GO:0007032 10 7 0,000 0,01155629 0,05101625 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01155629 0,05091852 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01155629 0,05082116 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01155629 0,05072417 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01155629 0,05062755 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01155629 0,0505313 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01155629 0,05043542 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01155629 0,0503399 ! galactose metabolic process GO:0006012 10 7 0,000 0,01155629 0,05024474 ! vesicle fusion GO:0006906 15 7 0,000 0,01155629 0,05014993 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01155629 0,05005549 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01155629 0,0499614 ! organ growth GO:0035265 11 7 0,000 0,01155629 0,04986766 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01155629 0,04977428 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01155629 0,04968124 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01155629 0,04958855 ! retinol metabolic process GO:0042572 9 7 0,000 0,01155629 0,04949621 ! behavioral fear response GO:0001662 13 7 0,000 0,01155629 0,04940421 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01155629 0,04931255 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01155629 0,04922123 ! rRNA modification GO:0000154 12 7 0,000 0,01155629 0,04913025 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01155629 0,0490396 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01155629 0,04894929 ! response to UV-B GO:0010224 11 7 0,000 0,01155629 0,04885931 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01155629 0,04876966 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01155629 0,04868034 ! intermediate filament organization GO:0045109 11 7 0,000 0,01155629 0,04859134 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01155629 0,04850267 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01155629 0,04841433 ! fibrinolysis GO:0042730 9 7 0,000 0,01155629 0,0483263 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01155629 0,04823859 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01155629 0,04815121 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01155629 0,04806413 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01155629 0,04797737 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01155629 0,04789093 ! response to tropane GO:0014073 13 7 0,000 0,01155629 0,04780479 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01155629 0,04771897 ! melanosome localization GO:0032400 10 7 0,000 0,01155629 0,04763345 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01155629 0,04754824 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01155629 0,04746333 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01155629 0,04737873 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01155629 0,04729442 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01155629 0,04721042 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01155629 0,04712671 ! mast cell activation GO:0045576 9 7 0,000 0,01155629 0,0470433 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01155629 0,04696019 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,01155629 0,04687736 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01155629 0,04679483 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01155629 0,04671259 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01155629 0,04663064 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01155629 0,04654898 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01155629 0,0464676 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01155629 0,0463865 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01155629 0,04630569 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01155629 0,04622516 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01155629 0,0461449 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01155629 0,04606493 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01155629 0,04598523 ! response to tumor cell GO:0002347 12 7 0,000 0,01155629 0,04590581 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01155629 0,04582666 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01155629 0,04574779 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01155629 0,04566918 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,01155629 0,04559085 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01155629 0,04551278 ! diuresis GO:0030146 12 7 0,000 0,01155629 0,04543498 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01155629 0,04535745 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01155629 0,04528018 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01155629 0,04520317 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01155629 0,04512643 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01155629 0,04504994 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01155629 0,04497371 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01155629 0,04489775 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01155629 0,04482203 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01155629 0,04474657 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01155629 0,04467137 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01155629 0,04459642 ! lymph node development GO:0048535 9 7 0,000 0,01155629 0,04452172 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01155629 0,04444727 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01155629 0,04437306 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01155629 0,04429911 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01155629 0,0442254 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01155629 0,04415194 ! ATP catabolic process GO:0006200 10 7 0,000 0,01155629 0,04407872 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01155629 0,04400574 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01155629 0,043933 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01155629 0,0438605 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01155629 0,04378825 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01155629 0,04371623 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01155629 0,04364444 ! muscle adaptation GO:0043500 12 7 0,000 0,01155629 0,04357289 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01155629 0,04350158 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01155629 0,0434305 ! retina homeostasis GO:0001895 9 7 0,000 0,01155629 0,04335965 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01155629 0,04328903 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01155629 0,04321864 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01155629 0,04314848 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01155629 0,04307855 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01155629 0,04300884 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01155629 0,04293936 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01155629 0,04287011 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,01166837 0,04321619 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01319663 0,04879781 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01319663 0,04871948 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01319663 0,04864141 ! axon extension GO:0048675 11 8 0,000 0,01319663 0,04856358 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01319663 0,048486 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01319663 0,04840867 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01319663 0,04833159 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01319663 0,04825475 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01319663 0,04817815 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01319663 0,0481018 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,01319663 0,04802569 ! phosphate transport GO:0006817 10 8 0,000 0,01319663 0,04794982 ! N-glycan processing GO:0006491 12 8 0,000 0,01319663 0,04787419 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01319663 0,0477988 ! UTP metabolic process GO:0046051 8 8 0,000 0,01319663 0,04772364 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01319663 0,04764872 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01319663 0,04757404 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01319663 0,04749959 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01319663 0,04742537 ! succinate metabolic process GO:0006105 14 8 0,000 0,01319663 0,04735138 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01319663 0,04727763 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01319663 0,0472041 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01319663 0,0471308 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01319663 0,04705773 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01319663 0,04698489 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01319663 0,04691227 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01319663 0,04683987 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01319663 0,0467677 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01319663 0,04669575 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01319663 0,04662402 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01319663 0,04655251 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01319663 0,04648122 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01319663 0,04641015 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01319663 0,04633929 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01319663 0,04626865 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01319663 0,04619823 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01319663 0,04612802 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01319663 0,04605802 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01319663 0,04598824 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01319663 0,04591866 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01319663 0,0458493 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01319663 0,04578015 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01319663 0,0457112 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01319663 0,04564246 ! melanin metabolic process GO:0006582 12 8 0,000 0,01319663 0,04557393 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01319663 0,0455056 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01319663 0,04543748 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01319663 0,04536956 ! macrophage activation GO:0042116 12 8 0,000 0,01319663 0,04530185 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01319663 0,04523433 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01319663 0,04516702 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01319663 0,04509991 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01319663 0,04503299 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01319663 0,04496628 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01319663 0,04489976 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01319663 0,04483344 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01319663 0,04476731 ! ruffle organization GO:0031529 11 8 0,000 0,01319663 0,04470138 ! osteoblast development GO:0002076 13 8 0,000 0,01319663 0,04463564 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01319663 0,0445701 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01319663 0,04450475 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01319663 0,04443959 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01319663 0,04437462 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01319663 0,04430984 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01319663 0,04424524 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01319663 0,04418084 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01319663 0,04411662 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01319663 0,04405259 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01319663 0,04398875 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01319663 0,04392509 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01319663 0,04386161 ! segment specification GO:0007379 10 8 0,000 0,01319663 0,04379832 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01319663 0,04373521 ! cellular extravasation GO:0045123 11 8 0,000 0,01319663 0,04367228 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01319663 0,04360954 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01319663 0,04354697 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01319663 0,04348458 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01319663 0,04342237 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01319663 0,04336034 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01319663 0,04329848 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01319663 0,04323681 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01319663 0,0431753 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01319663 0,04311397 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01319663 0,04305282 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01319663 0,04299184 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01319663 0,04293103 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01319663 0,04287039 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01319663 0,04280993 ! icosanoid secretion GO:0032309 12 8 0,000 0,01319663 0,04274963 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01319663 0,0426895 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01319663 0,04262955 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01319663 0,04256976 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01319663 0,04251014 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01319663 0,04245068 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01319663 0,04239139 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01319663 0,04233227 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01319663 0,04227331 ! sterol catabolic process GO:0016127 9 8 0,000 0,01319663 0,04221452 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01319663 0,04215589 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01319663 0,04209742 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01319663 0,04203911 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01319663 0,04198096 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01319663 0,04192298 ! prophase GO:0051324 11 8 0,000 0,01319663 0,04186516 ! S phase GO:0051320 8 8 0,000 0,01319663 0,04180749 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01319663 0,04174998 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01319663 0,04169263 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01319663 0,04163544 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01319663 0,04157841 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01319663 0,04152153 ! hormone catabolic process GO:0042447 13 8 0,000 0,01319663 0,04146481 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01319663 0,04140824 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01319663 0,04135182 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01319663 0,04129556 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01319663 0,04123945 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01319663 0,0411835 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01319663 0,04112769 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01319663 0,04107204 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01319663 0,04101654 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01319663 0,04096118 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01319663 0,04090598 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01319663 0,04085093 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01319663 0,04079602 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01319663 0,04074126 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01319663 0,04068665 GO:0000076|DNA replication checkpoint, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01319663 0,04063218 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01483433 0,04561359 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01483433 0,04555269 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01483433 0,04549195 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01483433 0,04543138 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01483433 0,04537096 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01483433 0,04531071 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01483433 0,04525062 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01483433 0,04519068 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01483433 0,04513091 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01483433 0,04507129 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01483433 0,04501183 ! GTP metabolic process GO:0046039 9 9 0,000 0,01483433 0,04495252 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01483433 0,04489337 ! social behavior GO:0035176 14 9 0,000 0,01483433 0,04483438 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01483433 0,04477554 ! artery development GO:0060840 19 9 0,000 0,01483433 0,04471686 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01483433 0,04465833 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01483433 0,04459995 ! response to pain GO:0048265 16 9 0,000 0,01483433 0,04454173 ! protein complex disassembly GO:0043241 17 9 0,000 0,01483433 0,04448366 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01483433 0,04442573 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01483433 0,04436796 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01483433 0,04431034 ! lung alveolus development GO:0048286 17 9 0,000 0,01483433 0,04425287 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01483433 0,04419555 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01483433 0,04413838 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01483433 0,04408135 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01483433 0,04402447 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01483433 0,04396774 ! protein targeting to ER GO:0045047 19 9 0,000 0,01483433 0,04391115 ! T cell selection GO:0045058 18 9 0,000 0,01483433 0,04385471 ! endoderm development GO:0007492 12 9 0,000 0,01483433 0,04379841 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01483433 0,04374226 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01483433 0,04368625 ! arginine catabolic process GO:0006527 10 9 0,000 0,01483433 0,04363039 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01483433 0,04357467 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01483433 0,04351909 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01483433 0,04346365 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01483433 0,04340835 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01483433 0,04335319 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01483433 0,04329818 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01483433 0,0432433 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01483433 0,04318856 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01483433 0,04313396 ! mannose metabolic process GO:0006013 9 9 0,000 0,01483433 0,0430795 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01483433 0,04302518 ! receptor clustering GO:0043113 15 9 0,000 0,01483433 0,04297099 ! epithelial cell development GO:0002064 10 9 0,000 0,01483433 0,04291694 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01483433 0,04286302 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01483433 0,04280924 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01483433 0,04275559 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01483433 0,04270208 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01483433 0,04264871 ! motor axon guidance GO:0008045 14 9 0,000 0,01483433 0,04259546 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01483433 0,04254235 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01483433 0,04248937 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01483433 0,04243652 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01483433 0,04238381 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01483433 0,04233122 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01483433 0,04227877 ! DNA ligation GO:0006266 14 9 0,000 0,01483433 0,04222644 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01483433 0,04217425 ! response to amine stimulus GO:0014075 13 9 0,000 0,01483433 0,04212218 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01483433 0,04207024 ! erythrocyte development GO:0048821 11 9 0,000 0,01483433 0,04201843 ! renal water homeostasis GO:0003091 14 9 0,000 0,01483433 0,04196675 ! postreplication repair GO:0006301 11 9 0,000 0,01483433 0,04191519 ! mRNA cleavage GO:0006379 13 9 0,000 0,01483433 0,04186376 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01483433 0,04181246 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01483433 0,04176128 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01483433 0,04171023 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01483433 0,0416593 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01483433 0,04160849 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01483433 0,04155781 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01483433 0,04150726 ! acid secretion GO:0046717 14 9 0,000 0,01483433 0,04145682 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01483433 0,04140651 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01483433 0,04135632 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01483433 0,04130625 ! purine base metabolic process GO:0006144 18 9 0,000 0,01483433 0,04125631 ! oocyte differentiation GO:0009994 12 9 0,000 0,01483433 0,04120648 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01483433 0,04115677 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01483433 0,04110719 ! spleen development GO:0048536 15 9 0,000 0,01483433 0,04105772 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01483433 0,04100837 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01483433 0,04095914 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01483433 0,04091003 ! detection of calcium ion GO:0005513 13 9 0,000 0,01483433 0,04086104 ! blastocyst formation GO:0001825 12 9 0,000 0,01483433 0,04081216 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01483433 0,0407634 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01483433 0,04071475 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01483433 0,04066623 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01483433 0,04061781 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01483433 0,04056952 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01483433 0,04052134 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01483433 0,04047327 ! prepulse inhibition GO:0060134 14 9 0,000 0,01483433 0,04042531 ! embryonic placenta development GO:0001892 12 9 0,000 0,01483433 0,04037747 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01483433 0,04032975 ! insulin secretion GO:0030073 17 9 0,000 0,01483433 0,04028213 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01483433 0,04023463 ! response to nicotine GO:0035094 16 9 0,000 0,01483433 0,04018724 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01483433 0,04013996 ! nucleus localization GO:0051647 15 9 0,000 0,01483433 0,04009279 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01483433 0,04004573 ! localization within membrane GO:0051668 15 9 0,000 0,01483433 0,03999879 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01646942 0,04435557 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01646942 0,04430369 ! neuron fate specification GO:0048665 11 10 0,000 0,01646942 0,04425193 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01646942 0,0442003 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01646942 0,04414878 ! thyroid gland development GO:0030878 19 10 0,000 0,01646942 0,04409739 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,01646942 0,04404611 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,01646942 0,04399495 ! synapsis GO:0007129 13 10 0,000 0,01646942 0,04394392 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01646942 0,043893 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01646942 0,04384219 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01646942 0,04379151 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01646942 0,04374094 ! sulfate transport GO:0008272 12 10 0,000 0,01646942 0,04369049 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01646942 0,04364016 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01646942 0,04358994 ! androgen metabolic process GO:0008209 13 10 0,000 0,01646942 0,04353983 ! phospholipid efflux GO:0033700 16 10 0,000 0,01646942 0,04348985 ! hippocampus development GO:0021766 19 10 0,000 0,01646942 0,04343997 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01646942 0,04339021 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01646942 0,04334057 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01646942 0,04329103 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01646942 0,04324162 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01646942 0,04319231 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,01646942 0,04314312 ! pathogenesis GO:0009405 13 10 0,000 0,01646942 0,04309403 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01646942 0,04304506 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01646942 0,0429962 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01646942 0,04294745 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01646942 0,04289882 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01646942 0,04285029 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,01646942 0,04280187 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01646942 0,04275356 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01646942 0,04270536 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01646942 0,04265727 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01646942 0,04260929 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01646942 0,04256141 ! response to X-ray GO:0010165 16 10 0,000 0,01646942 0,04251364 ! B cell proliferation GO:0042100 14 10 0,000 0,01646942 0,04246598 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01646942 0,04241843 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01646942 0,04237098 ! forebrain cell migration GO:0021885 17 10 0,000 0,01646942 0,04232364 ! lipid digestion GO:0044241 15 10 0,000 0,01646942 0,0422764 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01646942 0,04222927 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01646942 0,04218224 ! UV protection GO:0009650 14 10 0,000 0,01646942 0,04213532 ! entry into host cell GO:0030260 20 10 0,000 0,01646942 0,04208851 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01646942 0,04204179 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01646942 0,04199518 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01646942 0,04194868 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01646942 0,04190227 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01646942 0,04185597 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01646942 0,04180977 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01646942 0,04176368 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01646942 0,04171768 ! regulation of organ growth GO:0046620 11 10 0,000 0,01646942 0,04167179 ! response to dsRNA GO:0043331 18 10 0,000 0,01646942 0,04162599 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01646942 0,0415803 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01646942 0,04153471 ! embryonic axis specification GO:0000578 12 10 0,000 0,01646942 0,04148922 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01646942 0,04144382 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01646942 0,04139853 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01646942 0,04135334 ! cranial nerve development GO:0021545 12 10 0,000 0,01646942 0,04130824 ! fucose catabolic process GO:0019317 16 10 0,000 0,01646942 0,04126324 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01646942 0,04121834 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01646942 0,04117354 ! protein sumoylation GO:0016925 12 10 0,000 0,01646942 0,04112883 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01646942 0,04108422 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01646942 0,04103971 ! zymogen activation GO:0031638 14 10 0,000 0,01646942 0,0409953 ! salivary gland development GO:0007431 22 10 0,000 0,01646942 0,04095098 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01646942 0,04090676 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01646942 0,04086263 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01646942 0,04081859 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01646942 0,04077466 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,01646942 0,04073081 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01646942 0,04068706 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01646942 0,04064341 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01646942 0,04059984 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,01646942 0,04055638 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01646942 0,040513 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01646942 0,04046972 ! detection of bacterium GO:0016045 10 10 0,000 0,01646942 0,04042653 ! embryonic gut development GO:0048566 11 10 0,000 0,01646942 0,04038343 ! activation of innate immune response GO:0002218 10 10 0,000 0,01646942 0,04034042 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,01646942 0,04029751 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01646942 0,04025468 ! developmental induction GO:0031128 13 10 0,000 0,01646942 0,04021195 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01646942 0,04016931 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01646942 0,04012675 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01646942 0,04008429 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01646942 0,04004192 ! rRNA transcription GO:0009303 17 11 0,000 0,01810188 0,04396443 ! respiratory burst GO:0045730 14 11 0,000 0,01810188 0,04391806 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01810188 0,04387178 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01810188 0,0438256 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01810188 0,04377952 ! virus-host interaction GO:0019048 17 11 0,000 0,01810188 0,04373353 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,01810188 0,04368764 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,01810188 0,04364184 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,01810188 0,04359615 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,01810188 0,04355054 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01810188 0,04350504 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,01810188 0,04345962 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,01810188 0,04341431 ! mating GO:0007618 14 11 0,000 0,01810188 0,04336908 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01810188 0,04332395 ! T cell proliferation GO:0042098 20 11 0,000 0,01810188 0,04327892 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01810188 0,04323398 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,01810188 0,04318913 ! bone resorption GO:0045453 16 11 0,000 0,01810188 0,04314437 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01810188 0,04309971 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01810188 0,04305514 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01810188 0,04301066 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01810188 0,04296627 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01810188 0,04292198 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01810188 0,04287777 ! syncytium formation GO:0006949 15 11 0,000 0,01810188 0,04283366 ! plasma membrane organization GO:0007009 18 11 0,000 0,01810188 0,04278964 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01810188 0,04274571 ! focal adhesion formation GO:0048041 24 11 0,000 0,01810188 0,04270187 ! mitotic spindle organization GO:0007052 15 11 0,000 0,01810188 0,04265811 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,01810188 0,04261445 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01810188 0,04257088 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01810188 0,04252739 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01810188 0,042484 ! adult heart development GO:0007512 11 11 0,000 0,01810188 0,04244069 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01810188 0,04239747 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01810188 0,04235434 ! temperature homeostasis GO:0001659 16 11 0,000 0,01810188 0,0423113 ! L-glutamate transport GO:0015813 16 11 0,000 0,01810188 0,04226834 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,01810188 0,04222548 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01810188 0,04218269 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01810188 0,04214 ! stem cell development GO:0048864 29 11 0,000 0,01810188 0,04209739 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01810188 0,04205487 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01810188 0,04201243 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,01810188 0,04197008 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01810188 0,04192781 ! vasoconstriction GO:0042310 15 11 0,000 0,01810188 0,04188563 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01810188 0,04184354 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01810188 0,04180153 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01810188 0,0417596 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,01810188 0,04171775 ! ribosome assembly GO:0042255 13 11 0,000 0,01810188 0,041676 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01810188 0,04163432 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,01810188 0,04159273 ! chromatin silencing GO:0006342 19 11 0,000 0,01810188 0,04155122 ! nucleosome positioning GO:0016584 13 11 0,000 0,01810188 0,04150979 ! T cell homeostasis GO:0043029 20 11 0,000 0,01810188 0,04146845 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01810188 0,04142718 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,01810188 0,041386 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01810188 0,0413449 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01810188 0,04130389 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01810188 0,04126295 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01810188 0,0412221 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01810188 0,04118132 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01810188 0,04114063 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,01810188 0,04110002 ! male genitalia development GO:0030539 13 11 0,000 0,01810188 0,04105949 ! cholesterol efflux GO:0033344 19 11 0,000 0,01810188 0,04101903 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,01810188 0,04097866 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,01810188 0,04093837 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01810188 0,04089815 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01810188 0,04085802 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01810188 0,04081796 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01810188 0,04077798 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01810188 0,04073808 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01810188 0,04069826 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01810188 0,04065851 ! lysogeny GO:0030069 18 11 0,000 0,01810188 0,04061885 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,01810188 0,04057926 ! acrosome reaction GO:0007340 13 11 0,000 0,01810188 0,04053975 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01810188 0,04050031 ! lactation GO:0007595 20 12 0,000 0,01973172 0,04410395 ! reproductive cellular process GO:0048610 14 12 0,000 0,01973172 0,04406113 ! tRNA modification GO:0006400 14 12 0,000 0,01973172 0,0440184 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,01973172 0,04397574 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,01973172 0,04393317 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,01973172 0,04389068 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,01973172 0,04384828 ! non-recombinational repair GO:0000726 19 12 0,000 0,01973172 0,04380595 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,01973172 0,04376371 ! peroxisomal transport GO:0043574 21 12 0,000 0,01973172 0,04372155 ! cartilage condensation GO:0001502 18 12 0,000 0,01973172 0,04367947 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,01973172 0,04363747 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,01973172 0,04359555 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01973172 0,04355371 ! heart looping GO:0001947 15 12 0,000 0,01973172 0,04351195 ! palate development GO:0060021 15 12 0,000 0,01973172 0,04347027 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,01973172 0,04342868 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,01973172 0,04338716 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,01973172 0,04334572 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01973172 0,04330436 ! arginine metabolic process GO:0006525 13 12 0,000 0,01973172 0,04326308 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,01973172 0,04322187 ! methionine metabolic process GO:0006555 13 12 0,000 0,01973172 0,04318075 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,01973172 0,0431397 ! Golgi organization GO:0007030 18 12 0,000 0,01973172 0,04309873 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,01973172 0,04305784 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,01973172 0,04301703 ! monoamine transport GO:0015844 13 12 0,000 0,01973172 0,04297629 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01973172 0,04293563 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,01973172 0,04289505 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-amino acid transport GO:0015807 20 12 0,000 0,01973172 0,04285455 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,01973172 0,04281412 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01973172 0,04277377 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,01973172 0,04273349 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01973172 0,04269329 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,01973172 0,04265316 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,01973172 0,04261311 ! cerebellum development GO:0021549 13 12 0,000 0,01973172 0,04257314 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01973172 0,04253324 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01973172 0,04249341 ! histone acetylation GO:0016573 23 12 0,000 0,01973172 0,04245366 ! histone methylation GO:0016571 15 12 0,000 0,01973172 0,04241399 ! autonomic nervous system development GO:0048483 23 12 0,000 0,01973172 0,04237438 ! gland morphogenesis GO:0022612 23 12 0,000 0,01973172 0,04233486 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,01973172 0,0422954 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,01973172 0,04225602 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,01973172 0,04221671 ! response to gamma radiation GO:0010332 20 12 0,000 0,01973172 0,04217748 ! regulation of epidermis development GO:0045682 17 12 0,000 0,01973172 0,04213832 ! intestinal absorption GO:0050892 19 12 0,000 0,01973172 0,04209923 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,01973172 0,04206021 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01973172 0,04202126 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,01973172 0,04198239 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,01973172 0,04194359 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,01973172 0,04190486 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01973172 0,0418662 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,01973172 0,04182762 ! microspike assembly GO:0030035 23 12 0,000 0,01973172 0,0417891 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,01973172 0,04175066 ! response to cold GO:0009409 14 12 0,000 0,01973172 0,04171228 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,02135896 0,04511075 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,02135896 0,04506936 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02135896 0,04502805 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02135896 0,04498682 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,02135896 0,04494566 ! water transport GO:0006833 17 13 0,000 0,02135896 0,04490457 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02135896 0,04486357 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02135896 0,04482263 ! lipid localization GO:0010876 24 13 0,000 0,02135896 0,04478177 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02135896 0,04474099 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02135896 0,04470028 ! organelle fusion GO:0048284 28 13 0,000 0,02135896 0,04465964 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02135896 0,04461908 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02135896 0,04457859 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02135896 0,04453817 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02135896 0,04449783 ! response to hexose stimulus GO:0009746 19 13 0,000 0,02135896 0,04445756 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,02135896 0,04441736 ! glutamate metabolic process GO:0006536 18 13 0,000 0,02135896 0,04437724 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02135896 0,04433719 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02135896 0,04429721 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02135896 0,0442573 ! NAD metabolic process GO:0019674 21 13 0,000 0,02135896 0,04421747 ! exocrine system development GO:0035272 27 13 0,000 0,02135896 0,0441777 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02135896 0,04413801 ! bone mineralization GO:0030282 15 13 0,000 0,02135896 0,04409839 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02135896 0,04405884 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02135896 0,04401936 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02135896 0,04397995 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02135896 0,04394061 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,02135896 0,04390134 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02135896 0,04386215 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,02135896 0,04382302 ! genitalia development GO:0048806 15 13 0,000 0,02135896 0,04378396 ! regulation of cellular pH GO:0030641 20 13 0,000 0,02135896 0,04374497 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,02135896 0,04370605 ! cellular pigmentation GO:0033059 24 13 0,000 0,02135896 0,0436672 ! tissue regeneration GO:0042246 21 13 0,000 0,02135896 0,04362842 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02135896 0,04358971 ! cofactor transport GO:0051181 19 13 0,000 0,02135896 0,04355107 ! NADP metabolic process GO:0006739 18 13 0,000 0,02135896 0,04351249 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02135896 0,04347399 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02135896 0,04343555 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02135896 0,04339718 ! gas transport GO:0015669 18 13 0,000 0,02135896 0,04335887 ! regulation of RNA stability GO:0043487 28 13 0,000 0,02135896 0,04332064 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02135896 0,04328247 ! regulation of axon extension GO:0030516 23 13 0,000 0,02135896 0,04324437 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,02135896 0,04320634 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02135896 0,04316837 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02135896 0,04313047 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02135896 0,04309264 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02135896 0,04305487 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02135896 0,04301717 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,02298358 0,04624868 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,02298358 0,04620826 ! superoxide anion generation GO:0042554 18 14 0,000 0,02298358 0,0461679 ! neuron maturation GO:0042551 21 14 0,000 0,02298358 0,04612761 ! regulation of S phase GO:0033261 18 14 0,000 0,02298358 0,0460874 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,02298358 0,04604725 ! myotube differentiation GO:0014902 21 14 0,000 0,02298358 0,04600717 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,02298358 0,04596717 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,02298358 0,04592723 ! inositol metabolic process GO:0006020 20 14 0,000 0,02298358 0,04588736 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,02298358 0,04584757 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,02298358 0,04580784 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,02298358 0,04576818 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,02298358 0,04572858 ! gene silencing by RNA GO:0031047 20 14 0,000 0,02298358 0,04568906 ! response to cAMP GO:0051591 19 14 0,000 0,02298358 0,04564961 ! limbic system development GO:0021761 25 14 0,000 0,02298358 0,04561022 ! startle response GO:0001964 21 14 0,000 0,02298358 0,0455709 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,02298358 0,04553165 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,02298358 0,04549246 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,02298358 0,04545335 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,02298358 0,0454143 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,02298358 0,04537532 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,02298358 0,0453364 ! glycine metabolic process GO:0006544 22 14 0,000 0,02298358 0,04529755 ! pituitary gland development GO:0021983 23 14 0,000 0,02298358 0,04525877 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,02298358 0,04522005 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,02298358 0,04518141 ! regulation of heart rate GO:0002027 23 14 0,000 0,02298358 0,04514282 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,02298358 0,0451043 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,02298358 0,04506585 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,02298358 0,04502746 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,02298358 0,04498914 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,02298358 0,04495089 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,02298358 0,0449127 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,02298358 0,04487457 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,02298358 0,04483651 ! axon cargo transport GO:0008088 27 14 0,000 0,02298358 0,04479851 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,02298358 0,04476058 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,02298358 0,04472271 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,02298358 0,04468491 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,02298358 0,04464717 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02298358 0,04460949 ! mRNA splice site selection GO:0006376 26 14 0,000 0,02298358 0,04457188 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,02298358 0,04453433 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,02298358 0,04449684 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,02298358 0,04445941 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,02298358 0,04442205 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,02298358 0,04438476 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,02298358 0,04434752 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,02298358 0,04431035 ! muscle maintenance GO:0046716 19 14 0,000 0,02298358 0,04427324 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,02298358 0,04423619 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,02298358 0,0441992 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,02298358 0,04416228 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,02298358 0,04412541 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,02298358 0,04408861 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,02298358 0,04405187 ! cilium assembly GO:0042384 20 14 0,000 0,02298358 0,04401519 ! peptide hormone secretion GO:0030072 23 14 0,000 0,02298358 0,04397857 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,02460561 0,04704314 ! positive regulation of cell size GO:0045793 20 15 0,000 0,02460561 0,04700406 ! metencephalon development GO:0022037 19 15 0,000 0,02460561 0,04696506 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02460561 0,04692611 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,02460561 0,04688724 ! skin development GO:0043588 25 15 0,000 0,02460561 0,04684842 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,02460561 0,04680967 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,02460561 0,04677099 ! lipid phosphorylation GO:0046834 23 15 0,000 0,02460561 0,04673236 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,02460561 0,04669381 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,02460561 0,04665531 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,02460561 0,04661688 ! bile acid metabolic process GO:0008206 22 15 0,000 0,02460561 0,04657851 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,02460561 0,04654021 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,02460561 0,04650197 ! adult walking behavior GO:0007628 25 15 0,000 0,02460561 0,04646379 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02460561 0,04642567 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,02460561 0,04638762 ! myoblast differentiation GO:0045445 27 15 0,000 0,02460561 0,04634963 ! centrosome cycle GO:0007098 16 15 0,000 0,02460561 0,0463117 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,02460561 0,04627383 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,02460561 0,04623602 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,02460561 0,04619828 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,02460561 0,0461606 ! cerebral cortex development GO:0021987 29 15 0,000 0,02460561 0,04612298 ! response to osmotic stress GO:0006970 22 15 0,000 0,02460561 0,04608542 ! vesicle coating GO:0006901 25 15 0,000 0,02460561 0,04604792 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,02460561 0,04601048 ! DNA integration GO:0015074 22 15 0,000 0,02460561 0,04597311 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,02460561 0,04593579 ! peptide secretion GO:0002790 27 15 0,000 0,02460561 0,04589854 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,02460561 0,04586134 ! regulation of vasodilation GO:0042312 24 15 0,000 0,02460561 0,04582421 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,02460561 0,04578713 ! neuron recognition GO:0008038 22 15 0,000 0,02460561 0,04575012 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,02460561 0,04571316 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,02460561 0,04567627 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,02460561 0,04563943 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,02460561 0,04560265 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,02460561 0,04556594 ! biomineral formation GO:0031214 18 15 0,000 0,02460561 0,04552928 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,02460561 0,04549268 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,02460561 0,04545614 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,02460561 0,04541966 ! dopamine metabolic process GO:0042417 30 15 0,000 0,02460561 0,04538323 ! organic cation transport GO:0015695 19 15 0,000 0,02460561 0,04534687 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,02460561 0,04531056 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,02460561 0,04527432 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,02460561 0,04523812 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,02460561 0,04520199 ! defense response to virus GO:0051607 27 15 0,000 0,02460561 0,04516592 ! peptide hormone processing GO:0016486 19 15 0,000 0,02460561 0,0451299 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,02460561 0,04509394 ! protein secretion GO:0009306 27 16 0,000 0,02622503 0,04802354 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,02622503 0,04798533 ! hormone secretion GO:0046879 25 16 0,000 0,02622503 0,04794719 ! bone remodeling GO:0046849 24 16 0,000 0,02622503 0,04790911 ! endothelial cell migration GO:0043542 22 16 0,000 0,02622503 0,04787108 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,02622503 0,04783312 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,02622503 0,04779522 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02622503 0,04775737 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,02622503 0,04771959 ! glial cell development GO:0021782 24 16 0,000 0,02622503 0,04768187 ! patterning of blood vessels GO:0001569 24 16 0,000 0,02622503 0,04764421 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,02622503 0,0476066 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,02622503 0,04756906 ! protein polyubiquitination GO:0000209 26 16 0,000 0,02622503 0,04753157 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,02622503 0,04749414 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,02622503 0,04745678 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,02622503 0,04741947 ! fructose metabolic process GO:0006000 20 16 0,000 0,02622503 0,04738222 ! regulation of protein binding GO:0043393 27 16 0,000 0,02622503 0,04734503 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,02622503 0,04730789 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,02622503 0,04727082 ! protein export from nucleus GO:0006611 24 16 0,000 0,02622503 0,0472338 ! negative regulation of immune response GO:0050777 28 16 0,000 0,02622503 0,04719684 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,02622503 0,04715994 ! DNA replication initiation GO:0006270 25 16 0,000 0,02622503 0,0471231 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,02622503 0,04708631 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,02622503 0,04704958 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,02622503 0,04701291 ! diencephalon development GO:0021536 25 16 0,000 0,02622503 0,0469763 ! oogenesis GO:0048477 23 16 0,000 0,02622503 0,04693974 ! neural crest cell migration GO:0001755 24 16 0,000 0,02622503 0,04690324 ! G1 phase GO:0051318 27 16 0,000 0,02622503 0,04686679 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,02622503 0,04683041 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02622503 0,04679408 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,02622503 0,0467578 ! steroid catabolic process GO:0006706 22 16 0,000 0,02622503 0,04672158 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02622503 0,04668542 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,02622503 0,04664931 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,02622503 0,04661326 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,02622503 0,04657727 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,02622503 0,04654133 ! sperm-egg recognition GO:0035036 16 16 0,000 0,02622503 0,04650545 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,02622503 0,04646962 ! nerve development GO:0021675 18 16 0,000 0,02622503 0,04643384 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,02622503 0,04639813 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,02622503 0,04636246 ! negative regulation of translation GO:0017148 22 16 0,000 0,02622503 0,04632685 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,02784185 0,04914525 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,02784185 0,04910756 ! negative regulation of defense response GO:0031348 19 17 0,000 0,02784185 0,04906993 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,02784185 0,04903236 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,02784185 0,04899484 ! glycerol metabolic process GO:0006071 20 17 0,000 0,02784185 0,04895739 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,02784185 0,04891999 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,02784185 0,04888264 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02784185 0,04884536 ! signal complex assembly GO:0007172 29 17 0,000 0,02784185 0,04880813 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,02784185 0,04877095 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,02784185 0,04873384 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,02784185 0,04869678 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,02784185 0,04865977 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,02784185 0,04862283 ! keratinization GO:0031424 17 17 0,000 0,02784185 0,04858593 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,02784185 0,0485491 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,02784185 0,04851232 ! retinoid metabolic process GO:0001523 22 17 0,000 0,02784185 0,0484756 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,02784185 0,04843893 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,02784185 0,04840231 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,02784185 0,04836576 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,02784185 0,04832925 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,02784185 0,04829281 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,02784185 0,04825641 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,02784185 0,04822008 ! membrane budding GO:0006900 29 17 0,000 0,02784185 0,04818379 ! heme metabolic process GO:0042168 27 17 0,000 0,02784185 0,04814757 ! actin filament bundle formation GO:0051017 26 17 0,000 0,02784185 0,04811139 ! neuromuscular junction development GO:0007528 23 17 0,000 0,02784185 0,04807527 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,02784185 0,04803921 ! body fluid secretion GO:0007589 27 17 0,000 0,02784185 0,0480032 ! stem cell differentiation GO:0048863 36 17 0,000 0,02784185 0,04796724 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02784185 0,04793133 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,02784185 0,04789548 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,02784185 0,04785969 ! sensory perception of pain GO:0019233 23 17 0,000 0,02784185 0,04782394 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,02784185 0,04778826 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,02784185 0,04775262 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,02784185 0,04771704 ! synaptogenesis GO:0007416 24 17 0,000 0,02784185 0,04768151 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,02784185 0,04764603 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02784185 0,0476106 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,02784185 0,04757523 ! cell-cell junction organization GO:0045216 25 17 0,000 0,02784185 0,04753991 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,02784185 0,04750465 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,02784185 0,04746943 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,02784185 0,04743427 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,02784185 0,04739916 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,02784185 0,0473641 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,02784185 0,04732909 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,02945609 0,05003619 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,02945609 0,04999926 ! positive regulation of translation GO:0045727 28 18 0,000 0,02945609 0,04996239 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,02945609 0,04992557 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,02945609 0,04988881 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02945609 0,0498521 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,02945609 0,04981544 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02945609 0,04977884 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,02945609 0,04974229 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,02945609 0,0497058 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,02945609 0,04966935 ! axis specification GO:0009798 26 18 0,000 0,02945609 0,04963297 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,02945609 0,04959663 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,02945609 0,04956035 ! pancreas development GO:0031016 26 18 0,000 0,02945609 0,04952412 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,02945609 0,04948795 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,02945609 0,04945182 ! glutamine metabolic process GO:0006541 23 18 0,000 0,02945609 0,04941575 ! response to retinoic acid GO:0032526 25 18 0,000 0,02945609 0,04937974 ! pigmentation during development GO:0048066 31 18 0,000 0,02945609 0,04934377 ! central nervous system neuron development GO:0021954 30 18 0,000 0,02945609 0,04930786 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,02945609 0,049272 ! fucose metabolic process GO:0006004 26 18 0,000 0,02945609 0,04923619 ! response to fungus GO:0009620 19 18 0,000 0,02945609 0,04920044 ! peptide cross-linking GO:0018149 31 18 0,000 0,02945609 0,04916473 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,02945609 0,04912908 ! heart process GO:0003015 27 18 0,000 0,02945609 0,04909348 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,02945609 0,04905793 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,02945609 0,04902243 ! visual learning GO:0008542 35 18 0,000 0,02945609 0,04898698 ! somitogenesis GO:0001756 24 18 0,000 0,02945609 0,04895159 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,02945609 0,04891624 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,02945609 0,04888095 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,02945609 0,04884571 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,02945609 0,04881052 ! vitamin transport GO:0051180 24 18 0,000 0,02945609 0,04877538 ! hormone transport GO:0009914 27 18 0,000 0,02945609 0,04874029 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,02945609 0,04870525 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,02945609 0,04867026 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02945609 0,04863532 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,02945609 0,04860043 ! cell-cell recognition GO:0009988 20 18 0,000 0,02945609 0,04856559 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,02945609 0,0485308 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,02945609 0,04849606 ! regulation of glucose import GO:0046324 21 18 0,000 0,02945609 0,04846137 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,02945609 0,04842673 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,02945609 0,04839214 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,02945609 0,0483576 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,02945609 0,04832311 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,03106773 0,05093071 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,03106773 0,05089443 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,03106773 0,05085821 ! positive regulation of ossification GO:0045778 30 19 0,000 0,03106773 0,05082204 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,03106773 0,05078592 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,03106773 0,05074985 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,03106773 0,05071383 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,03106773 0,05067786 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,03106773 0,05064194 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,03106773 0,05060608 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,03106773 0,05057026 ! regeneration GO:0031099 32 19 0,000 0,03106773 0,0505345 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,03106773 0,05049879 ! response to alkaloid GO:0043279 32 19 0,000 0,03106773 0,05046312 ! sensory perception of taste GO:0050909 23 19 0,000 0,03106773 0,05042751 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,03106773 0,05039195 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,03106773 0,05035644 ! smooth muscle contraction GO:0006939 36 19 0,000 0,03106773 0,05032097 ! peroxisome organization GO:0007031 29 19 0,000 0,03106773 0,05028556 ! digestive system process GO:0022600 30 19 0,000 0,03106773 0,0502502 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,03106773 0,05021489 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,03106773 0,05017962 ! response to vitamin A GO:0033189 26 19 0,000 0,03106773 0,05014441 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,03106773 0,05010924 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,03106773 0,05007413 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,03106773 0,05003906 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,03106773 0,05000405 ! sex determination GO:0007530 29 19 0,000 0,03106773 0,04996908 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,03106773 0,04993416 ! plasma membrane fusion GO:0045026 23 19 0,000 0,03106773 0,04989929 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,03106773 0,04986447 ! cytolysis GO:0019835 20 19 0,000 0,03106773 0,0498297 ! renal system process GO:0003014 35 19 0,000 0,03106773 0,04979497 ! vasodilation GO:0042311 33 19 0,000 0,03106773 0,04976029 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,03106773 0,04972567 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,03106773 0,04969109 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,03106773 0,04965656 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,03106773 0,04962207 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,03106773 0,04958764 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,03106773 0,04955325 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,03106773 0,04951891 ! sarcomere organization GO:0045214 23 19 0,000 0,03106773 0,04948461 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,03106773 0,04945037 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,03106773 0,04941617 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,03106773 0,04938202 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,03106773 0,04934792 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,03106773 0,04931386 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,03106773 0,04927985 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,03106773 0,04924589 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,03106773 0,04921197 ! protein stabilization GO:0050821 26 19 0,000 0,03106773 0,0491781 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,03267679 0,05168956 ! iron ion transport GO:0006826 37 20 0,000 0,03267679 0,05165404 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,03267679 0,05161856 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,03267679 0,05158313 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,03267679 0,05154775 ! response to vitamin GO:0033273 29 20 0,000 0,03267679 0,05151242 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,03267679 0,05147714 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,03267679 0,05144191 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,03267679 0,05140672 ! spinal cord development GO:0021510 31 20 0,000 0,03267679 0,05137158 ! response to ethanol GO:0045471 37 20 0,000 0,03267679 0,05133649 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,03267679 0,05130145 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,03267679 0,05126646 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,03267679 0,05123151 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,03267679 0,05119661 ! chromosome condensation GO:0030261 31 20 0,000 0,03267679 0,05116176 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,03267679 0,05112696 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,03267679 0,0510922 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,03267679 0,05105749 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,03267679 0,05102283 ! pallium development GO:0021543 38 20 0,000 0,03267679 0,05098821 ! DNA modification GO:0006304 28 20 0,000 0,03267679 0,05095364 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,03267679 0,05091912 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,03267679 0,05088465 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,03267679 0,05085022 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,03267679 0,05081584 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,03267679 0,0507815 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,03267679 0,05074721 ! collagen catabolic process GO:0030574 25 20 0,000 0,03267679 0,05071297 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,03267679 0,05067878 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,03267679 0,05064463 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,03267679 0,05061052 ! alditol metabolic process GO:0019400 24 20 0,000 0,03267679 0,05057646 ! actin filament-based movement GO:0030048 34 20 0,000 0,03267679 0,05054245 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,03428327 0,05299162 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,03428327 0,05295603 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,03428327 0,05292049 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,03428327 0,052885 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,03428327 0,05284955 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,03428327 0,05281415 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,03428327 0,0527788 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,03428327 0,0527435 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,03428327 0,05270824 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,03428327 0,05267303 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,03428327 0,05263787 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,03428327 0,05260276 ! protein amino acid acylation GO:0043543 37 21 0,000 0,03428327 0,05256769 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,03428327 0,05253267 ! vesicle docking GO:0048278 27 21 0,000 0,03428327 0,05249769 ! phototransduction GO:0007602 25 21 0,000 0,03428327 0,05246276 ! dendrite development GO:0016358 35 21 0,000 0,03428327 0,05242788 ! visual behavior GO:0007632 39 21 0,000 0,03428327 0,05239304 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,03428327 0,05235825 ! ovarian follicle development GO:0001541 30 21 0,000 0,03428327 0,05232351 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,03428327 0,05228881 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,03428327 0,05225416 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,03428327 0,05221956 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,03428327 0,052185 ! cell aging GO:0007569 32 21 0,000 0,03428327 0,05215048 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,03428327 0,05211601 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,03428327 0,05208159 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,03428327 0,05204721 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,03428327 0,05201288 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,03428327 0,0519786 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,03428327 0,05194435 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,03428327 0,05191016 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,03428327 0,05187601 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,03428327 0,0518419 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,03428327 0,05180784 ! fatty acid transport GO:0015908 30 21 0,000 0,03428327 0,05177382 ! immunoglobulin production GO:0002377 33 21 0,000 0,03428327 0,05173985 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,03428327 0,05170592 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,03428327 0,05167204 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,03428327 0,0516382 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,03428327 0,0516044 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,03428327 0,05157065 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,03428327 0,05153695 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,03428327 0,05150329 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,03428327 0,05146967 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,03428327 0,05143609 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,03428327 0,05140256 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,03428327 0,05136908 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,03428327 0,05133563 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,03428327 0,05130223 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,03428327 0,05126888 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,03588718 0,05363256 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,03588718 0,05359774 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,03588718 0,05356295 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,03588718 0,05352822 ! viral genome replication GO:0019079 29 22 0,000 0,03588718 0,05349353 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,03588718 0,05345888 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,03588718 0,05342428 ! molting cycle process GO:0022404 40 22 0,000 0,03588718 0,05338972 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,03588718 0,05335521 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,03588718 0,05332074 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,03588718 0,05328632 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,03588718 0,05325194 ! vasculogenesis GO:0001570 33 22 0,000 0,03588718 0,05321761 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,03588718 0,05318332 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,03588718 0,05314907 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,03588718 0,05311487 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,03588718 0,05308072 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,03588718 0,0530466 ! lysosome organization GO:0007040 37 22 0,000 0,03588718 0,05301253 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,03588718 0,05297851 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,03588718 0,05294452 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,03588718 0,05291058 ! regulation of behavior GO:0050795 38 22 0,000 0,03588718 0,05287669 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,03588718 0,05284284 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,03588718 0,05280903 ! membrane depolarization GO:0051899 35 22 0,000 0,03588718 0,05277526 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,03588718 0,05274154 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,03588718 0,05270786 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,03588718 0,05267423 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,03588718 0,05264063 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,03588718 0,05260708 ! blastocyst development GO:0001824 37 22 0,000 0,03588718 0,05257357 ! neural tube closure GO:0001843 33 22 0,000 0,03588718 0,05254011 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,03588718 0,05250669 ! protein tetramerization GO:0051262 39 22 0,000 0,03588718 0,05247331 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,03748851 0,05477991 ! neuron fate commitment GO:0048663 32 23 0,000 0,03748851 0,05474513 ! embryonic pattern specification GO:0009880 31 23 0,000 0,03748851 0,05471039 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,03748851 0,0546757 ! myelination GO:0042552 35 23 0,000 0,03748851 0,05464105 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,03748851 0,05460645 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,03748851 0,05457188 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,03748851 0,05453737 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,03748851 0,05450289 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,03748851 0,05446846 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,03748851 0,05443408 ! vesicle targeting GO:0006903 32 23 0,000 0,03748851 0,05439973 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,03748851 0,05436543 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,03748851 0,05433118 ! osteoblast differentiation GO:0001649 40 23 0,000 0,03748851 0,05429696 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,03748851 0,05426279 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,03748851 0,05422867 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,03748851 0,05419458 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,03748851 0,05416054 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,03748851 0,05412654 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,03748851 0,05409258 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,03748851 0,05405867 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,03748851 0,0540248 ! cell fate determination GO:0001709 45 23 0,000 0,03748851 0,05399097 ! pentose metabolic process GO:0019321 31 23 0,000 0,03748851 0,05395718 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,03748851 0,05392344 ! spermatid development GO:0007286 33 23 0,000 0,03748851 0,05388974 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,03748851 0,05385608 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,03748851 0,05382246 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,03748851 0,05378888 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,03748851 0,05375535 ! telomere organization GO:0032200 32 23 0,000 0,03748851 0,05372186 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,03748851 0,0536884 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,03748851 0,053655 ! regulation of amine transport GO:0051952 38 23 0,000 0,03748851 0,05362163 ! liver development GO:0001889 40 23 0,000 0,03748851 0,0535883 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,03908728 0,05583897 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,03908728 0,05580431 ! initiation of viral infection GO:0019059 42 24 0,000 0,03908728 0,05576969 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,03908728 0,05573511 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,03908728 0,05570058 ! superoxide metabolic process GO:0006801 32 24 0,000 0,03908728 0,05566609 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,03908728 0,05563164 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,03908728 0,05559724 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,03908728 0,05556288 ! fat cell differentiation GO:0045444 37 24 0,000 0,03908728 0,05552856 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,03908728 0,05549428 ! sperm motility GO:0030317 27 24 0,000 0,03908728 0,05546005 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,03908728 0,05542585 ! vacuole organization GO:0007033 39 24 0,000 0,03908728 0,0553917 ! receptor metabolic process GO:0043112 37 24 0,000 0,03908728 0,0553576 ! neural crest cell development GO:0014032 39 24 0,000 0,03908728 0,05532353 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,03908728 0,05528951 ! primary neural tube formation GO:0014020 35 24 0,000 0,03908728 0,05525552 ! negative regulation of cell development GO:0010721 56 24 0,000 0,03908728 0,05522158 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,03908728 0,05518768 ! base-excision repair GO:0006284 31 24 0,000 0,03908728 0,05515383 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,03908728 0,05512001 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,03908728 0,05508624 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,03908728 0,0550525 ! glutathione metabolic process GO:0006749 29 24 0,000 0,03908728 0,05501881 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,03908728 0,05498516 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,03908728 0,05495155 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,03908728 0,05491798 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,04068348 0,05712576 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,04068348 0,05709091 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,04068348 0,0570561 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,04068348 0,05702133 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,04068348 0,0569866 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,04068348 0,05695192 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,04068348 0,05691727 ! peptide transport GO:0015833 43 25 0,000 0,04068348 0,05688267 ! male gonad development GO:0008584 33 25 0,000 0,04068348 0,05684812 ! iron ion homeostasis GO:0055072 39 25 0,000 0,04068348 0,0568136 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,04068348 0,05677912 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,04068348 0,05674469 ! phospholipid transport GO:0015914 35 25 0,000 0,04068348 0,0567103 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,04068348 0,05667595 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,04068348 0,05664165 ! detection of light stimulus GO:0009583 30 25 0,000 0,04068348 0,05660738 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,04068348 0,05657315 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,04068348 0,05653897 ! leukocyte proliferation GO:0070661 39 25 0,000 0,04068348 0,05650483 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,04068348 0,05647073 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,04227712 0,05864739 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,04227712 0,05861204 ! translational initiation GO:0006413 43 26 0,000 0,04227712 0,05857673 ! regulation of pH GO:0006885 36 26 0,000 0,04227712 0,05854146 ! circadian rhythm GO:0007623 42 26 0,000 0,04227712 0,05850624 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,04227712 0,05847106 ! post-embryonic development GO:0009791 42 26 0,000 0,04227712 0,05843592 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,04227712 0,05840082 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,04227712 0,05836577 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,04227712 0,05833076 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,04227712 0,05829579 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,04227712 0,05826086 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,04227712 0,05822597 ! regulation of coagulation GO:0050818 39 26 0,000 0,04227712 0,05819113 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,0438682 0,06034501 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,0438682 0,06030894 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,0438682 0,06027292 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,0438682 0,06023693 ! membrane docking GO:0022406 39 27 0,000 0,0438682 0,06020099 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,0438682 0,06016509 ! catechol metabolic process GO:0009712 43 27 0,000 0,0438682 0,06012924 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,0438682 0,06009343 ! acute-phase response GO:0006953 42 27 0,000 0,0438682 0,06005766 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,0438682 0,06002193 ! myofibril assembly GO:0030239 36 27 0,000 0,0438682 0,05998624 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,0438682 0,0599506 ! response to ionizing radiation GO:0010212 47 27 0,000 0,0438682 0,059915 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,0438682 0,05987944 ! natural killer cell activation GO:0030101 35 27 0,000 0,0438682 0,05984393 ! lipid oxidation GO:0034440 38 27 0,000 0,0438682 0,05980846 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,0438682 0,05977302 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,0438682 0,05973763 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,0438682 0,05970229 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,0438682 0,05966698 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,0438682 0,05963172 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,0438682 0,05959649 ! gene silencing GO:0016458 41 27 0,000 0,0438682 0,05956131 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,04545673 0,0616817 ! phenol metabolic process GO:0018958 44 28 0,000 0,04545673 0,06164533 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,04545673 0,06160901 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,04545673 0,06157272 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,04545673 0,06153648 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,04545673 0,06150029 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,04545673 0,06146413 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,04545673 0,06142802 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,04545673 0,06139195 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,04545673 0,06135592 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,04545673 0,06131993 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,04545673 0,06128399 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,04545673 0,06124809 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,04545673 0,06121223 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,04545673 0,06117641 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,04545673 0,06114064 ! mesoderm formation GO:0001707 46 28 0,000 0,04545673 0,0611049 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,04545673 0,06106921 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,04545673 0,06103356 ! ensheathment of neurons GO:0007272 43 28 0,000 0,04545673 0,06099795 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,04545673 0,06096238 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,04545673 0,06092686 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,04545673 0,06089137 ! neural tube formation GO:0001841 41 28 0,000 0,04545673 0,06085593 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,04545673 0,06082053 ! placenta development GO:0001890 37 28 0,000 0,04545673 0,06078517 ! regulation of B cell activation GO:0050864 42 28 0,000 0,04545673 0,06074985 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,04704272 0,0628329 ! regulation of innate immune response GO:0045088 38 29 0,000 0,04704272 0,06279643 ! ovulation cycle process GO:0022602 41 29 0,000 0,04704272 0,06276001 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,04704272 0,06272362 ! protein targeting to membrane GO:0006612 53 29 0,000 0,04704272 0,06268728 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,04704272 0,06265098 ! mismatch repair GO:0006298 34 29 0,000 0,04704272 0,06261473 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,04704272 0,06257851 ! muscle cell development GO:0055001 38 29 0,000 0,04704272 0,06254234 ! formation of primary germ layer GO:0001704 48 29 0,000 0,04704272 0,06250621 ! telencephalon development GO:0021537 52 29 0,000 0,04704272 0,06247012 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,04704272 0,06243407 ! eye morphogenesis GO:0048592 51 29 0,000 0,04704272 0,06239807 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,04704272 0,0623621 ! tissue homeostasis GO:0001894 42 29 0,000 0,04704272 0,06232618 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,04862616 0,06438697 ! collagen metabolic process GO:0032963 40 30 0,000 0,04862616 0,06434992 ! organic anion transport GO:0015711 51 30 0,000 0,04862616 0,06431291 ! cholesterol transport GO:0030301 46 30 0,000 0,04862616 0,06427595 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,04862616 0,06423903 ! spliceosome assembly GO:0000245 49 30 0,000 0,04862616 0,06420216 ! spindle organization GO:0007051 37 30 0,000 0,04862616 0,06416532 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,04862616 0,06412853 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,04862616 0,06409178 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,04862616 0,06405507 ! ovulation cycle GO:0042698 43 30 0,000 0,04862616 0,06401841 ! hindbrain development GO:0030902 45 30 0,000 0,04862616 0,06398178 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,04862616 0,0639452 ! adult locomotory behavior GO:0008344 47 30 0,000 0,04862616 0,06390866 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,04862616 0,06387216 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,04862616 0,06383571 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,04862616 0,06379929 ! response to heat GO:0009408 41 30 0,000 0,04862616 0,06376292 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,04862616 0,06372659 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,04862616 0,0636903 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,05020705 0,06572352 ! negative regulation of secretion GO:0051048 49 31 0,000 0,05020705 0,06568613 ! mammary gland development GO:0030879 57 31 0,000 0,05020705 0,06564879 ! glial cell differentiation GO:0010001 55 31 0,000 0,05020705 0,06561149 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,05020705 0,06557423 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,05020705 0,06553702 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,05020705 0,06549984 ! odontogenesis GO:0042476 50 31 0,000 0,05020705 0,06546271 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,05020705 0,06542562 ! segmentation GO:0035282 41 31 0,000 0,05020705 0,06538858 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,05020705 0,06535157 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,05020705 0,06531461 ! metanephros development GO:0001656 58 31 0,000 0,05020705 0,06527769 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,05020705 0,06524081 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,05020705 0,06520397 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,05020705 0,06516717 ! cell fate specification GO:0001708 37 31 0,000 0,05020705 0,06513041 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,05020705 0,0650937 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,05020705 0,06505703 ! RNA modification GO:0009451 40 31 0,000 0,05020705 0,0650204 ! regulation of muscle development GO:0048634 48 32 0,000 0,05178542 0,06702671 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,05178542 0,06698901 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,05178542 0,06695135 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,05178542 0,06691374 ! meiosis I GO:0007127 52 32 0,000 0,05178542 0,06687617 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,05178542 0,06683864 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,05178542 0,06680115 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,05178542 0,06676371 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,05178542 0,06672631 ! peripheral nervous system development GO:0007422 53 32 0,000 0,05178542 0,06668895 ! regulation of protein stability GO:0031647 48 32 0,000 0,05178542 0,06665163 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,05178542 0,06661435 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,05178542 0,06657711 ! cytokine production GO:0001816 44 32 0,000 0,05178542 0,06653992 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,05178542 0,06650277 ! vesicle localization GO:0051648 47 32 0,000 0,05178542 0,06646566 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,05336125 0,06845001 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,05336125 0,06841185 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,05336125 0,06837374 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,05336125 0,06833567 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,05336125 0,06829764 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,05336125 0,06825966 ! sister chromatid segregation GO:0000819 46 33 0,000 0,05336125 0,06822172 ! ear morphogenesis GO:0042471 42 33 0,000 0,05336125 0,06818381 ! actomyosin structure organization GO:0031032 43 33 0,000 0,05336125 0,06814596 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,05336125 0,06810814 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,05336125 0,06807036 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,05336125 0,06803263 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,05336125 0,06799494 ! female gonad development GO:0008585 49 33 0,000 0,05336125 0,06795729 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,05336125 0,06791968 ! positive regulation of cell development GO:0010720 54 33 0,000 0,05336125 0,06788212 ! lipid homeostasis GO:0055088 55 33 0,000 0,05336125 0,06784459 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,05336125 0,06780711 ! regulation of proteolysis GO:0030162 50 33 0,000 0,05336125 0,06776967 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,05336125 0,06773227 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,05336125 0,06769491 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,05336125 0,06765759 ! cytokinesis GO:0000910 52 33 0,000 0,05336125 0,06762031 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,05336125 0,06758308 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,05493455 0,0695374 ! mRNA catabolic process GO:0006402 48 34 0,000 0,05493455 0,06949915 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,05493455 0,06946094 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,05493455 0,06942278 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,05493455 0,06938466 ! feeding behavior GO:0007631 45 34 0,000 0,05493455 0,06934657 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,05493455 0,06930853 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,05493455 0,06927054 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,05493455 0,06923258 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,05493455 0,06919466 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,05493455 0,06915679 ! neuron migration GO:0001764 46 34 0,000 0,05493455 0,06911896 ! female gamete generation GO:0007292 43 34 0,000 0,05493455 0,06908117 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,05493455 0,06904342 ! polyol metabolic process GO:0019751 44 34 0,000 0,05493455 0,06900571 ! aerobic respiration GO:0009060 47 34 0,000 0,05493455 0,06896804 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,05493455 0,06893042 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,05493455 0,06889283 ! embryonic organ development GO:0048568 45 34 0,000 0,05493455 0,06885529 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,05493455 0,06881779 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,05650532 0,070747 ! Notch signaling pathway GO:0007219 56 35 0,000 0,05650532 0,07070851 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,05650532 0,07067006 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,05650532 0,07063165 ! keratinocyte differentiation GO:0030216 47 35 0,000 0,05650532 0,07059329 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,05650532 0,07055496 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,05650532 0,07051668 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,05650532 0,07047844 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,05650532 0,07044024 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,05650532 0,07040208 ! glycogen metabolic process GO:0005977 48 35 0,000 0,05650532 0,07036396 ! pigment metabolic process GO:0042440 61 35 0,000 0,05650532 0,07032589 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,05650532 0,07028785 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,05650532 0,07024986 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,05807358 0,07216058 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,05807358 0,07212161 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,05807358 0,07208269 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,05807358 0,07204381 ! negative regulation of binding GO:0051100 58 36 0,000 0,05807358 0,07200497 ! organic ether metabolic process GO:0018904 46 36 0,000 0,05807358 0,07196618 ! tissue remodeling GO:0048771 62 36 0,000 0,05807358 0,07192743 ! neural tube development GO:0021915 50 36 0,000 0,05807358 0,07188871 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,05807358 0,07185004 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,05807358 0,07181141 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,05807358 0,07177283 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,05807358 0,07173428 ! glucan metabolic process GO:0044042 49 36 0,000 0,05807358 0,07169577 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,05963932 0,07358928 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,05963932 0,07354983 ! learning GO:0007612 67 37 0,000 0,05963932 0,07351041 ! ion transmembrane transport GO:0034220 56 37 0,000 0,05963932 0,07347104 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,05963932 0,07343171 ! regulation of protein secretion GO:0050708 51 37 0,000 0,05963932 0,07339242 ! amino acid activation GO:0043038 52 37 0,000 0,05963932 0,07335317 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,05963932 0,07331396 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,06120254 0,07519543 ! gliogenesis GO:0042063 71 38 0,000 0,06120254 0,07515528 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,06120254 0,07511518 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,06120254 0,07507512 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,06120254 0,0750351 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,06120254 0,07499512 ! phagocytosis GO:0006909 60 38 0,000 0,06120254 0,07495519 ! mesenchymal cell development GO:0014031 64 38 0,000 0,06120254 0,0749153 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,06276326 0,07678483 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,06276326 0,07674401 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,06276326 0,07670324 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,06276326 0,0766625 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,06276326 0,07662181 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,06276326 0,07658116 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,06276326 0,07654056 ! male sex differentiation GO:0046661 53 39 0,000 0,06276326 0,07649999 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,06276326 0,07645948 ! chromatin remodeling GO:0006338 68 39 0,000 0,06276326 0,076419 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,06276326 0,07637857 ! JNK cascade GO:0007254 54 39 0,000 0,06276326 0,07633818 ! developmental growth GO:0048589 62 39 0,000 0,06276326 0,07629783 ! cell growth GO:0016049 61 39 0,000 0,06276326 0,07625752 ! synapse organization GO:0050808 55 39 0,000 0,06276326 0,07621726 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,06432147 0,07806827 ! response to calcium ion GO:0051592 58 40 0,000 0,06432147 0,0780271 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,06432147 0,07798596 ! regulation of tube size GO:0035150 60 40 0,000 0,06432147 0,07794488 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,06432147 0,07790383 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,06432147 0,07786283 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,06432147 0,07782187 ! peptide metabolic process GO:0006518 56 40 0,000 0,06432147 0,07778095 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,06432147 0,07774008 ! inner ear development GO:0048839 57 40 0,000 0,06432147 0,07769925 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,06432147 0,07765846 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,06432147 0,07761772 ! double-strand break repair GO:0006302 67 40 0,000 0,06432147 0,07757702 ! B cell differentiation GO:0030183 62 40 0,000 0,06432147 0,07753636 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,06432147 0,07749574 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,06432147 0,07745517 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,06432147 0,07741464 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,06432147 0,07737415 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,06587718 0,07920413 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,06587718 0,07916275 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,06587718 0,07912141 ! glucose transport GO:0015758 52 41 0,000 0,06587718 0,07908012 ! endosome transport GO:0016197 71 41 0,000 0,06587718 0,07903887 ! striated muscle contraction GO:0006941 62 41 0,000 0,06587718 0,07899766 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,06587718 0,07895649 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,06587718 0,07891537 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,06587718 0,07887429 ! biopolymer methylation GO:0043414 62 41 0,000 0,06587718 0,07883325 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,06587718 0,07879225 ! mitochondrial transport GO:0006839 60 42 0,000 0,06743039 0,08060805 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,06743039 0,08056618 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,06743039 0,08052435 ! cellular component disassembly GO:0022411 64 42 0,000 0,06743039 0,08048256 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,06743039 0,08044081 ! hexose transport GO:0008645 54 42 0,000 0,06743039 0,08039911 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,06743039 0,08035746 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,06743039 0,08031584 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,06743039 0,08027427 ! excretion GO:0007588 63 42 0,000 0,06743039 0,08023274 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,06743039 0,08019126 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,06743039 0,08014981 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,06743039 0,08010841 ! regulation of cell shape GO:0008360 78 42 0,000 0,06743039 0,08006706 ! positive regulation of binding GO:0051099 59 43 0,000 0,06898111 0,08186612 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 0,000 0,06898111 0,0818239 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,06898111 0,08178172 ! leukocyte migration GO:0050900 60 43 0,000 0,06898111 0,08173959 ! neuromuscular process GO:0050905 79 43 0,000 0,06898111 0,0816975 ! activation of caspase activity GO:0006919 65 43 0,000 0,06898111 0,08165545 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,06898111 0,08161345 ! tRNA processing GO:0008033 49 43 0,000 0,06898111 0,08157149 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,06898111 0,08152957 ! vesicle organization GO:0016050 79 43 0,000 0,06898111 0,08148769 ! response to insulin stimulus GO:0032868 63 43 0,000 0,06898111 0,08144586 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,06898111 0,08140407 ! methylation GO:0032259 64 43 0,000 0,06898111 0,08136233 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,07052933 0,08314581 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,07052933 0,08310321 ! glycolysis GO:0006096 53 44 0,000 0,07052933 0,08306066 ! regulation of action potential GO:0001508 71 44 0,000 0,07052933 0,08301815 ! regulation of ion transport GO:0043269 57 44 0,000 0,07052933 0,08297569 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,07052933 0,08293327 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,07052933 0,08289089 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,07052933 0,08284855 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,07052933 0,08280626 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,07052933 0,08276401 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,07052933 0,08272181 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,07052933 0,08267965 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,07052933 0,08263753 ! positive regulation of cell cycle GO:0045787 77 45 0,000 0,07207508 0,08440564 ! RNA catabolic process GO:0006401 64 45 0,000 0,07207508 0,08436268 ! positive regulation of defense response GO:0031349 59 45 0,000 0,07207508 0,08431977 ! regulation of translational initiation GO:0006446 64 45 0,000 0,07207508 0,08427691 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,07207508 0,08423408 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,07207508 0,0841913 ! cell recognition GO:0008037 58 45 0,000 0,07207508 0,08414856 ! cell maturation GO:0048469 60 45 0,000 0,07207508 0,08410587 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,07207508 0,08406322 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,07361834 0,08581965 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,07361834 0,08577618 ! cell redox homeostasis GO:0045454 63 46 0,000 0,07361834 0,08573274 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,07361834 0,08568936 ! regulation of ossification GO:0030278 71 46 0,000 0,07361834 0,08564601 ! histone modification GO:0016570 68 46 0,000 0,07361834 0,08560272 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,07361834 0,08555946 ! response to UV GO:0009411 75 46 0,000 0,07361834 0,08551625 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,07515912 0,08726197 ! viral infectious cycle GO:0019058 71 47 0,000 0,07515912 0,08721795 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,07515912 0,08717396 ! endocrine system development GO:0035270 83 47 0,000 0,07515912 0,08713002 ! covalent chromatin modification GO:0016569 75 47 0,000 0,07515912 0,08708613 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,07515912 0,08704228 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,07515912 0,08699847 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,07515912 0,08695471 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,07515912 0,08691099 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,07515912 0,08686732 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,07515912 0,08682369 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,07515912 0,0867801 ! chloride transport GO:0006821 67 48 0,000 0,07669742 0,08851183 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,07669742 0,08846744 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,07669742 0,0884231 ! response to temperature stimulus GO:0009266 62 48 0,000 0,07669742 0,0883788 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,07669742 0,08833454 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,07669742 0,08829033 ! gastrulation GO:0007369 73 48 0,000 0,07669742 0,08824616 ! heart morphogenesis GO:0003007 65 48 0,000 0,07669742 0,08820204 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,07669742 0,08815796 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,07669742 0,08811392 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,07669742 0,08806993 ! regulation of endocytosis GO:0030100 63 48 0,000 0,07669742 0,08802599 ! nuclear export GO:0051168 69 48 0,000 0,07669742 0,08798208 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,07669742 0,08793822 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,07669742 0,08789441 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,07823326 0,08960981 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,07823326 0,08956521 ! sensory perception of smell GO:0007608 61 49 0,000 0,07823326 0,08952065 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,07823326 0,08947613 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,07823326 0,08943166 ! RNA elongation GO:0006354 62 49 0,000 0,07823326 0,08938723 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,07823326 0,08934285 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,07823326 0,08929851 ! germ cell development GO:0007281 68 49 0,000 0,07823326 0,08925422 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,07823326 0,08920996 ! cartilage development GO:0051216 70 49 0,000 0,07823326 0,08916576 ! regulation of actin filament length GO:0030832 72 50 0,000 0,07976663 0,09086838 ! ear development GO:0043583 72 50 0,000 0,07976663 0,09082339 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,07976663 0,09077845 ! membrane fusion GO:0006944 80 50 0,000 0,07976663 0,09073356 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,07976663 0,0906887 ! lipid modification GO:0030258 73 50 0,000 0,07976663 0,0906439 ! positive regulation of growth GO:0045927 67 50 0,000 0,07976663 0,09059914 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,07976663 0,09055442 ! proton transport GO:0015992 75 50 0,000 0,07976663 0,09050974 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,07976663 0,09046511 ! positive regulation of secretion GO:0051047 71 51 0,000 0,08129754 0,09215591 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 0,000 0,08129754 0,09211051 ! hydrogen transport GO:0006818 77 51 0,000 0,08129754 0,09206516 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,08129754 0,09201985 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,08129754 0,09197459 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,08129754 0,09192937 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,08129754 0,09188419 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,08129754 0,09183906 ! adult behavior GO:0030534 80 51 0,000 0,08129754 0,09179398 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,08129754 0,09174894 ! transition metal ion transport GO:0000041 74 52 0,000 0,08282598 0,09342804 ! regulation of cellular component size GO:0032535 74 52 0,000 0,08282598 0,09338224 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,08282598 0,09333648 ! aging GO:0007568 79 52 0,000 0,08282598 0,09329078 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,08282598 0,09324511 ! establishment of organelle localization GO:0051656 85 52 0,000 0,08282598 0,09319949 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,08435198 0,09487019 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,08435198 0,09482383 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,08435198 0,0947775 ! kidney development GO:0001822 90 53 0,000 0,08435198 0,09473122 ! single fertilization GO:0007338 59 53 0,000 0,08435198 0,09468499 ! cell projection assembly GO:0030031 76 53 0,000 0,08435198 0,0946388 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,08587552 0,09630117 ! regulation of mitosis GO:0007088 84 54 0,000 0,08587552 0,09625424 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,08587552 0,09620735 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,08587552 0,09616051 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,08587552 0,09611372 ! DNA catabolic process GO:0006308 67 54 0,000 0,08587552 0,09606697 ! detection of external stimulus GO:0009581 66 54 0,000 0,08587552 0,09602027 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,08587552 0,09597361 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,08587552 0,095927 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,08587552 0,09588043 ! exocytosis GO:0006887 74 55 0,000 0,08739661 0,0975314 ! mesoderm development GO:0007498 76 55 0,000 0,08739661 0,0974841 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,08739661 0,09743684 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,08739661 0,09738963 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,08891526 0,09903395 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,08891526 0,09898601 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,08891526 0,09893812 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,08891526 0,09889028 ! carbohydrate transport GO:0008643 74 57 0,000 0,09043147 0,10052797 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,09043147 0,10047941 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,09043147 0,10043089 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,09043147 0,10038242 ! camera-type eye development GO:0043010 88 57 0,000 0,09043147 0,100334 ! secondary metabolic process GO:0019748 84 57 0,000 0,09043147 0,10028562 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,09043147 0,10023729 ! developmental maturation GO:0021700 75 57 0,000 0,09043147 0,10018901 ! gonad development GO:0008406 79 57 0,000 0,09043147 0,10014077 ! viral reproductive process GO:0022415 87 58 0,000 0,09194524 0,10176807 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,09194524 0,10171912 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,09194524 0,10167022 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,09194524 0,10162136 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,09345658 0,10324214 ! activation of MAPK activity GO:0000187 84 59 0,000 0,09345658 0,10319258 ! lung development GO:0030324 94 59 0,000 0,09345658 0,10314306 ! actin filament organization GO:0007015 95 59 0,000 0,09345658 0,10309359 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,09345658 0,10304417 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,09345658 0,1029948 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,09496549 0,10460758 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,09496549 0,10455751 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,09496549 0,10450748 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,09496549 0,1044575 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,09496549 0,10440757 ! regulation of heart contraction GO:0008016 91 60 0,000 0,09496549 0,10435768 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,09496549 0,10430785 ! fertilization GO:0009566 68 60 0,000 0,09496549 0,10425806 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,09496549 0,10420832 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,09647198 0,10581094 ! meiosis GO:0007126 96 61 0,000 0,09647198 0,10576051 GO:0051327|M phase of meiotic cell cycle, ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,09647198 0,10571012 ! urogenital system development GO:0001655 101 61 0,000 0,09647198 0,10565979 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,09647198 0,1056095 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,09647198 0,10555925 ! extracellular matrix organization GO:0030198 103 61 0,000 0,09647198 0,10550906 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,09647198 0,10545891 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,09647198 0,10540881 ! amine catabolic process GO:0009310 90 62 0,000 0,09797604 0,10700138 ! neurotransmitter transport GO:0006836 81 62 0,000 0,09797604 0,10695059 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,09797604 0,10689986 ! respiratory tube development GO:0030323 99 62 0,000 0,09797604 0,10684917 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,09797604 0,10679853 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,09797604 0,10674794 ! meiotic cell cycle GO:0051321 97 62 0,000 0,09797604 0,1066974 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,09947769 0,10828144 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,09947769 0,10823022 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,09947769 0,10817905 ! viral reproduction GO:0016032 92 63 0,000 0,09947769 0,10812792 ! regulation of lipase activity GO:0060191 109 63 0,000 0,09947769 0,10807685 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,10097692 0,10965388 ! appendage morphogenesis GO:0035107 93 64 0,000 0,10097692 0,10960214 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,10097692 0,10955044 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,10097692 0,10949879 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,10097692 0,10944718 ! hexose catabolic process GO:0019320 82 64 0,000 0,10097692 0,10939563 ! respiratory system development GO:0060541 100 64 0,000 0,10097692 0,10934413 ! adaptive immune response GO:0002250 94 64 0,000 0,10097692 0,10929267 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,10247375 0,11086059 ! regulation of caspase activity GO:0043281 97 65 0,000 0,10247375 0,11080847 ! appendage development GO:0048736 94 65 0,000 0,10247375 0,1107564 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,10247375 0,11070438 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,10247375 0,1106524 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,10247375 0,11060048 ! defense response to bacterium GO:0042742 73 65 0,000 0,10247375 0,1105486 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,10247375 0,11049677 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,10247375 0,110445 ! activation of immune response GO:0002253 83 65 0,000 0,10247375 0,11039326 ! protein oligomerization GO:0051259 100 65 0,000 0,10247375 0,11034158 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,10396816 0,11189835 ! antigen processing and presentation GO:0019882 96 66 0,000 0,10396816 0,11184601 ! axon guidance GO:0007411 99 66 0,000 0,10396816 0,11179373 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,10396816 0,11174149 ! regulation of immune effector process GO:0002697 101 66 0,000 0,10396816 0,11168929 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,10546018 0,11323922 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,10546018 0,11318638 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,10546018 0,11313359 ! acute inflammatory response GO:0002526 92 68 0,000 0,10694979 0,1146781 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,10694979 0,11462466 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,10694979 0,11457128 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,10694979 0,11451794 ! rhythmic process GO:0048511 105 68 0,000 0,10694979 0,11446465 ! inorganic anion transport GO:0015698 93 68 0,000 0,10694979 0,11441141 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,10843702 0,11594846 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,10843702 0,11589458 ! response to drug GO:0042493 108 69 0,000 0,10843702 0,11584075 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,10843702 0,11578697 ! response to metal ion GO:0010038 103 70 0,000 0,10992184 0,11731798 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,10992184 0,11726356 ! humoral immune response GO:0006959 86 70 0,000 0,10992184 0,1172092 ! eye development GO:0001654 111 70 0,000 0,10992184 0,11715488 ! positive regulation of phosphorylation GO:0042327 102 70 0,000 0,10992184 0,11710062 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,10992184 0,11704641 ! regulation of catabolic process GO:0009894 106 70 0,000 0,10992184 0,11699224 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,11140429 0,1185152 ! muscle cell differentiation GO:0042692 104 71 0,000 0,11140429 0,11846041 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,11140429 0,11840566 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,11140429 0,11835097 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,11140429 0,11829633 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,11140429 0,11824174 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,11140429 0,1181872 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,11288434 0,11970216 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 0,000 0,11288434 0,119647 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 0,000 0,11288434 0,11959189 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,11288434 0,11953683 ! negative regulation of transport GO:0051051 116 73 0,000 0,11436202 0,12104586 ! regulation of blood pressure GO:0008217 107 73 0,000 0,11436202 0,12099018 ! tube morphogenesis GO:0035239 118 73 0,000 0,11436202 0,12093455 ! mitochondrion organization GO:0007005 104 73 0,000 0,11436202 0,12087897 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,11436202 0,12082345 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,11436202 0,12076797 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,11583732 0,12226977 ! response to oxygen levels GO:0070482 137 74 0,000 0,11583732 0,12221369 ! digestion GO:0007586 97 74 0,000 0,11583732 0,12215765 ! protein import into nucleus GO:0006606 118 74 0,000 0,11583732 0,12210167 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,11583732 0,12204573 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,11583732 0,12198985 ! blood coagulation GO:0007596 116 75 0,000 0,11731025 0,12348447 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,11731025 0,12342798 ! response to nutrient GO:0007584 104 75 0,000 0,11731025 0,12337154 ! regulation of ligase activity GO:0051340 114 75 0,000 0,11731025 0,12331516 ! nuclear import GO:0051170 121 75 0,000 0,11731025 0,12325882 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,11731025 0,12320254 ! amine biosynthetic process GO:0009309 97 76 0,000 0,1187808 0,12469003 ! tRNA metabolic process GO:0006399 95 76 0,000 0,1187808 0,12463314 ! response to unfolded protein GO:0006986 99 76 0,000 0,1187808 0,12457631 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,1187808 0,12451953 ! regulation of protein transport GO:0051223 114 76 0,000 0,1187808 0,1244628 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,120249 0,12594385 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,120249 0,12588652 ! regulation of DNA binding GO:0051101 119 77 0,000 0,120249 0,12582925 ! gland development GO:0048732 148 77 0,000 0,120249 0,12577203 ! sex differentiation GO:0007548 105 77 0,000 0,120249 0,12571486 ! protein ubiquitination GO:0016567 125 77 0,000 0,120249 0,12565774 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,120249 0,12560068 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,120249 0,12554366 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,120249 0,1254867 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,12171483 0,12695878 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,12171483 0,12690123 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,12171483 0,12684373 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,1231783 0,12831073 ! cellular respiration GO:0045333 107 79 0,000 0,1231783 0,12825264 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,1231783 0,12819461 ! T cell activation GO:0042110 134 79 0,000 0,1231783 0,12813663 ! regulation of lyase activity GO:0051339 133 79 0,000 0,1231783 0,1280787 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,1231783 0,12802083 ! chromatin assembly GO:0031497 102 80 0,000 0,12463942 0,12948088 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,12463942 0,12942242 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,12463942 0,12936402 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,12463942 0,12930567 ! forebrain development GO:0030900 131 80 0,000 0,12463942 0,12924737 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,12609818 0,13070114 ! hemostasis GO:0007599 125 81 0,000 0,12609818 0,13064226 ! mRNA transport GO:0051028 121 81 0,000 0,12609818 0,13058344 ! response to protein stimulus GO:0051789 111 81 0,000 0,12609818 0,13052467 ! regulation of neurological system process GO:0031644 122 81 0,000 0,12609818 0,13046596 ! vitamin metabolic process GO:0006766 103 81 0,000 0,12609818 0,13040729 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,12609818 0,13034868 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,1275546 0,13179496 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,1275546 0,13173578 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,12900868 0,13317772 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,12900868 0,13311797 ! regulation of defense response GO:0031347 117 84 0,000 0,13046041 0,13455558 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,13046041 0,13449527 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,13046041 0,13443502 ! sterol metabolic process GO:0016125 120 84 0,000 0,13046041 0,13437481 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,13190981 0,13580688 ! rRNA metabolic process GO:0016072 107 85 0,000 0,13190981 0,13574612 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,13190981 0,13568541 ! transcription initiation GO:0006352 118 85 0,000 0,13190981 0,13562475 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,13190981 0,13556415 ! regulation of protein localization GO:0032880 132 85 0,000 0,13190981 0,13550361 ! regulation of membrane potential GO:0042391 128 85 0,000 0,13190981 0,13544311 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,13190981 0,13538267 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,13335688 0,13680679 ! cell cycle arrest GO:0007050 150 86 0,000 0,13335688 0,1367458 ! interphase of mitotic cell cycle GO:0051329 156 86 0,000 0,13335688 0,13668486 ! nucleosome organization GO:0034728 114 87 0,000 0,13480162 0,13810411 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,13480162 0,13804262 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,13480162 0,13798118 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,13480162 0,1379198 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,13480162 0,13785848 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,13480162 0,13779721 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,13624403 0,1392098 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,13624403 0,13914799 ! interphase GO:0051325 159 88 0,000 0,13624403 0,13908623 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,13624403 0,13902452 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,13624403 0,13896287 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,13624403 0,13890127 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,13768412 0,14030725 ! reproductive developmental process GO:0003006 127 89 0,000 0,13768412 0,14024512 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,13768412 0,14018303 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,13768412 0,14012101 ! regulation of T cell activation GO:0050863 128 89 0,000 0,13768412 0,14005903 ! leukocyte differentiation GO:0002521 143 90 0,000 0,13912189 0,14145904 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,13912189 0,14139653 ! hormone metabolic process GO:0042445 121 90 0,000 0,13912189 0,14133408 ! RNA localization GO:0006403 135 91 0,000 0,14055735 0,14272932 ! ATP metabolic process GO:0046034 137 91 0,000 0,14055735 0,14266633 ! response to virus GO:0009615 122 91 0,000 0,14055735 0,1426034 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,14199049 0,14399389 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,14199049 0,14393043 ! cell fate commitment GO:0045165 141 92 0,000 0,14199049 0,14386702 ! positive regulation of immune response GO:0050778 121 92 0,000 0,14199049 0,14380367 ! sulfur metabolic process GO:0006790 118 92 0,000 0,14199049 0,14374038 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,14342133 0,14512497 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,14342133 0,14506115 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,14342133 0,14499739 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,14342133 0,14493368 ! electron transport chain GO:0022900 123 94 0,000 0,14484987 0,146313 ! response to oxidative stress GO:0006979 141 94 0,000 0,14484987 0,14624877 ! regulation of binding GO:0051098 151 95 0,000 0,1462761 0,14762397 ! angiogenesis GO:0001525 149 95 0,000 0,1462761 0,14755922 ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,14770004 0,14893033 ! in utero embryonic development GO:0001701 147 96 0,000 0,14770004 0,14886507 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,14770004 0,14879986 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,14770004 0,14873471 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,14770004 0,14866962 ! protein maturation GO:0051604 129 96 0,000 0,14770004 0,14860459 ! response to light stimulus GO:0009416 153 96 0,000 0,14770004 0,14853961 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,14912168 0,14990379 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,14912168 0,1498383 ! calcium ion transport GO:0006816 167 99 0,000 0,1519581 0,15262168 ! extracellular structure organization GO:0043062 156 99 0,000 0,1519581 0,15255506 ! protein import GO:0017038 156 99 0,000 0,1519581 0,1524885 ! regulation of translation GO:0006417 151 100 0,000 0,15337289 0,1538411 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,15337289 0,15377404 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,15337289 0,15370703 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,15337289 0,15364009 ! divalent metal ion transport GO:0070838 171 100 0,000 0,15337289 0,1535732 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,15337289 0,15350637 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,15337289 0,1534396 ! protein localization in organelle GO:0033365 161 100 0,000 0,15337289 0,15337289