pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-pos-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/55-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 1,63E-05 0,03921636 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 1,000 1,63E-05 0,01960818 ! interaction with symbiont GO:0051702 13 6 1,000 2,443E-05 0,01959212 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 3,417E-05 0,02055489 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 3,417E-05 0,01644391 ! mitochondrion localization GO:0051646 15 9 1,000 5,849E-05 0,02345285 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 6,207E-05 0,0213336 ! cell-matrix adhesion GO:0007160 163 75 2,000 1,271E-04 0,03822201 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 1,472E-04 0,03936091 ! neutral amino acid transport GO:0015804 26 14 1,000 1,472E-04 0,03542482 ! cell-substrate adhesion GO:0031589 171 81 2,000 1,597E-04 0,03493539 ! heterophilic cell adhesion GO:0007157 39 15 1,000 1,697E-04 0,03403445 ! cell killing GO:0001906 29 15 1,000 1,697E-04 0,03141642 ! dicarboxylic acid transport GO:0006835 38 16 1,000 1,938E-04 0,03331259 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 2,195E-04 0,03520849 ! memory GO:0007613 31 18 1,000 2,467E-04 0,03710357 ! cell-substrate junction assembly GO:0007044 54 18 1,000 2,467E-04 0,03492101 ! cellular response to starvation GO:0009267 33 20 1,000 3,059E-04 0,04088976 ! inactivation of MAPK activity GO:0000188 39 21 1,000 3,378E-04 0,04278029 ! leukocyte adhesion GO:0007159 50 23 1,000 4,063E-04 0,04888301 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 4,429E-04 0,05074601 ! response to starvation GO:0042594 42 25 1,000 4,81E-04 0,05260844 ! interaction with host GO:0051701 62 25 1,000 4,81E-04 0,05032112 ! cellular response to nutrient levels GO:0031669 41 25 1,000 4,81E-04 0,0482244 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 5,207E-04 0,05011237 GO:0045936|negative regulation of phosphate metabolic process, ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 5,619E-04 0,05199723 ! regulation of chromosome organization GO:0033044 42 27 1,000 5,619E-04 0,0500714 ! negative regulation of protein modification process GO:0031400 60 28 1,000 6,046E-04 0,05195472 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 6,489E-04 0,05383493 ! cell junction assembly GO:0034329 78 30 1,000 6,947E-04 0,05571203 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 6,947E-04 0,05391487 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 7,42E-04 0,05578647 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 7,908E-04 0,05765521 ! ceramide metabolic process GO:0006672 64 33 1,000 8,411E-04 0,05952108 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 8,93E-04 0,06138406 ! cell junction organization GO:0034330 86 36 1,000 1,001E-03 0,06690967 ! sphingoid metabolic process GO:0046519 70 36 1,000 1,001E-03 0,0651013 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 1,001E-03 0,06338811 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 1,235E-03 0,07621866 ! maintenance of location in cell GO:0051651 97 44 1,000 1,494E-03 0,08983455 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 1,562E-03 0,09164502 ! pigmentation GO:0043473 100 46 1,000 1,631E-03 0,09345314 ! regulation of DNA replication GO:0006275 101 56 1,000 2,408E-03 0,13471314 ! maintenance of location GO:0051235 118 57 1,000 2,493E-03 0,13632752 ! skeletal system morphogenesis GO:0048705 105 59 1,000 2,668E-03 0,14266984 ! regulation of Rab protein signal transduction GO:0032483 92 59 1,000 2,668E-03 0,13956832 GO:0032313|regulation of Rab GTPase activity, ! sphingolipid metabolic process GO:0006665 107 61 1,000 2,849E-03 0,14586106 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 3,426E-03 0,1717152 ! negative regulation of cell growth GO:0030308 132 67 1,000 3,426E-03 0,16821081 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 3,426E-03 0,16484659 ! amino acid transport GO:0006865 125 68 1,000 3,527E-03 0,16637602 ! negative regulation of kinase activity GO:0033673 131 68 1,000 3,527E-03 0,16317648 ! membrane lipid metabolic process GO:0006643 117 68 1,000 3,527E-03 0,16009768 ! negative regulation of cell size GO:0045792 134 69 1,000 3,629E-03 0,16169158 ! negative regulation of transferase activity GO:0051348 140 72 1,000 3,944E-03 0,17253985 ! learning or memory GO:0007611 147 73 1,000 4,052E-03 0,17409034 ! organelle localization GO:0051640 136 74 1,000 4,161E-03 0,17564395 ! negative regulation of organelle organization GO:0010639 161 78 1,000 4,611E-03 0,19129144 ! negative regulation of growth GO:0045926 155 84 1,000 5,327E-03 0,21723088 ! amine transport GO:0015837 155 86 1,000 5,576E-03 0,22360175 ! regulation of cell adhesion GO:0030155 212 89 1,000 5,96E-03 0,23506689 ! regulation of cell cycle process GO:0010564 149 90 1,000 6,09E-03 0,23633934 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 6,458E-03 0,24665048 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 6,458E-03 0,24279657 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 6,458E-03 0,23906123 ! positive regulation of helicase activity GO:0051096 11 5 0,000 6,458E-03 0,23543909 ! neuron fate determination GO:0048664 7 5 0,000 6,458E-03 0,23192508 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,458E-03 0,22851442 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 6,458E-03 0,22520261 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 6,458E-03 0,22198543 ! polyol transport GO:0015791 12 5 0,000 6,458E-03 0,21885888 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 6,458E-03 0,21581917 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 6,458E-03 0,21286274 ! response to superoxide GO:0000303 10 5 0,000 6,458E-03 0,20998622 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,458E-03 0,2071864 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 6,458E-03 0,20446027 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 6,458E-03 0,20180494 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 6,458E-03 0,1992177 ! female meiosis GO:0007143 7 5 0,000 6,458E-03 0,19669595 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 6,458E-03 0,19423725 ! cobalt ion transport GO:0006824 11 5 0,000 6,458E-03 0,19183926 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 6,458E-03 0,18949976 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 6,458E-03 0,18721663 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 6,458E-03 0,18498786 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 6,458E-03 0,18281153 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 6,458E-03 0,18068582 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 6,458E-03 0,17860897 ! embryonic camera-type eye development GO:0031076 10 5 0,000 6,458E-03 0,17657932 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 6,458E-03 0,17459528 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 6,458E-03 0,17265534 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 6,458E-03 0,17075802 ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,458E-03 0,16890196 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 6,458E-03 0,16708581 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 6,458E-03 0,1653083 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 6,458E-03 0,16356821 ! negative chemotaxis GO:0050919 14 5 0,000 6,458E-03 0,16186438 ! positive regulation of histone modification GO:0031058 5 5 0,000 6,458E-03 0,16019567 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,458E-03 0,15856102 ! sensory perception of bitter taste GO:0050913 7 5 0,000 6,458E-03 0,1569594 ! behavioral response to pain GO:0048266 9 5 0,000 6,458E-03 0,1553898 ! clathrin coat assembly GO:0048268 14 5 0,000 6,458E-03 0,15385129 ! Notch receptor processing GO:0007220 8 5 0,000 6,458E-03 0,15234294 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,458E-03 0,15086389 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 6,458E-03 0,14941327 ! micturition GO:0060073 9 5 0,000 6,458E-03 0,14799029 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 6,458E-03 0,14659415 ! copulation GO:0007620 9 5 0,000 6,458E-03 0,14522411 ! glial cell fate commitment GO:0021781 13 5 0,000 6,458E-03 0,14387945 ! protein maturation by protein folding GO:0022417 13 5 0,000 6,458E-03 0,14255945 ! spermidine metabolic process GO:0008216 7 5 0,000 6,458E-03 0,14126346 ! regulation of potassium ion transport GO:0043266 10 5 0,000 6,458E-03 0,13999081 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 6,458E-03 0,13874089 ! apoptotic cell clearance GO:0043277 20 5 0,000 6,458E-03 0,1375131 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 6,458E-03 0,13630684 ! lipoprotein particle clearance GO:0034381 10 5 0,000 6,458E-03 0,13512157 ! grooming behavior GO:0007625 6 5 0,000 6,458E-03 0,13395673 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 6,458E-03 0,1328118 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 6,458E-03 0,13168627 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,458E-03 0,13057967 ! response to protozoan GO:0001562 10 5 0,000 6,458E-03 0,1294915 ! positive regulation of glycolysis GO:0045821 14 5 0,000 6,458E-03 0,12842132 ! lymph vessel development GO:0001945 10 5 0,000 6,458E-03 0,12736869 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 6,458E-03 0,12633317 ! endochondral ossification GO:0001958 16 5 0,000 6,458E-03 0,12531436 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 6,458E-03 0,12431184 ! parathyroid gland development GO:0060017 13 5 0,000 6,458E-03 0,12332524 ! anagen GO:0042640 6 5 0,000 6,458E-03 0,12235418 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 6,458E-03 0,12139828 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 6,458E-03 0,12045721 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 6,458E-03 0,11953062 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 6,458E-03 0,11861817 ! dorsal spinal cord development GO:0021516 7 5 0,000 6,458E-03 0,11771955 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 6,458E-03 0,11683444 ! sphingoid catabolic process GO:0046521 6 5 0,000 6,458E-03 0,11596254 ! skeletal myofibril assembly GO:0014866 10 5 0,000 6,458E-03 0,11510356 ! smooth muscle tissue development GO:0048745 28 5 0,000 6,458E-03 0,11425721 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,458E-03 0,11342321 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 6,458E-03 0,11260131 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 6,458E-03 0,11179122 ! cardiac muscle fiber development GO:0048739 10 5 0,000 6,458E-03 0,11099272 ! transepithelial chloride transport GO:0030321 9 5 0,000 6,458E-03 0,11020553 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,458E-03 0,10942944 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 6,458E-03 0,1086642 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 6,458E-03 0,10790958 ! neutrophil mediated immunity GO:0002446 7 5 0,000 6,458E-03 0,10716538 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 6,458E-03 0,10643137 ! histidine catabolic process GO:0006548 6 5 0,000 6,458E-03 0,10570735 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 6,458E-03 0,10499311 ! microvillus organization GO:0032528 7 5 0,000 6,458E-03 0,10428846 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 6,458E-03 0,1035932 ! L-serine biosynthetic process GO:0006564 6 5 0,000 6,458E-03 0,10290715 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 6,458E-03 0,10223013 ! tryptophan metabolic process GO:0006568 9 5 0,000 6,458E-03 0,10156196 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 6,458E-03 0,10090247 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 6,458E-03 0,10025149 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 6,458E-03 0,09960885 ! polyol catabolic process GO:0046174 7 5 0,000 6,458E-03 0,0989744 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 6,458E-03 0,09834798 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 6,458E-03 0,09772944 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 6,458E-03 0,09711863 ! muscle cell migration GO:0014812 8 5 0,000 6,458E-03 0,09651541 ! mitochondrial fission GO:0000266 8 5 0,000 6,458E-03 0,09591963 ! sister chromatid cohesion GO:0007062 12 5 0,000 6,458E-03 0,09533117 ! mRNA transcription GO:0009299 9 5 0,000 6,458E-03 0,09474988 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 6,458E-03 0,09417564 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 6,458E-03 0,09360831 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 6,458E-03 0,09304779 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 6,458E-03 0,09249393 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 6,458E-03 0,09194663 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 6,458E-03 0,09140577 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 6,458E-03 0,09087123 ! response to food GO:0032094 6 5 0,000 6,458E-03 0,09034291 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 6,458E-03 0,0898207 ! positive regulation of transporter activity GO:0032411 8 5 0,000 6,458E-03 0,08930448 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 6,458E-03 0,08879417 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,458E-03 0,08828966 ! paraxial mesoderm development GO:0048339 14 5 0,000 6,458E-03 0,08779085 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 6,458E-03 0,08729764 ! forebrain neuron development GO:0021884 13 5 0,000 6,458E-03 0,08680995 ! lipoprotein catabolic process GO:0042159 11 5 0,000 6,458E-03 0,08632767 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 6,458E-03 0,08585072 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 6,458E-03 0,08537901 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,458E-03 0,08491246 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 6,458E-03 0,08445098 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 6,458E-03 0,08399449 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,458E-03 0,0835429 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 6,458E-03 0,08309615 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 6,458E-03 0,08265415 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 6,458E-03 0,08221683 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 6,458E-03 0,08178411 ! basic amino acid transport GO:0015802 11 5 0,000 6,458E-03 0,08135592 ! cellular glucose homeostasis GO:0001678 5 5 0,000 6,458E-03 0,08093219 ! early endosome to late endosome transport GO:0045022 12 5 0,000 6,458E-03 0,08051285 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,458E-03 0,08009784 ! depyrimidination GO:0045008 10 5 0,000 6,458E-03 0,07968708 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,458E-03 0,07928051 ! regulation of centrosome cycle GO:0046605 7 5 0,000 6,458E-03 0,07887807 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 6,458E-03 0,0784797 ! zinc ion homeostasis GO:0055069 8 5 0,000 6,458E-03 0,07808533 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 6,458E-03 0,0776949 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 6,458E-03 0,07730836 ! forebrain morphogenesis GO:0048853 13 5 0,000 6,458E-03 0,07692564 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 6,458E-03 0,0765467 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 6,458E-03 0,07617147 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 6,458E-03 0,0757999 ! peptidyl-arginine modification GO:0018195 9 5 0,000 6,458E-03 0,07543194 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,458E-03 0,07506754 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,458E-03 0,07470664 ! response to arsenic GO:0046685 10 5 0,000 6,458E-03 0,07434919 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 6,458E-03 0,07399514 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 6,458E-03 0,07364446 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 6,458E-03 0,07329708 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 6,458E-03 0,07295296 ! response to cadmium ion GO:0046686 7 5 0,000 6,458E-03 0,07261206 ! bile acid biosynthetic process GO:0006699 6 5 0,000 6,458E-03 0,07227433 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 6,458E-03 0,07193972 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 6,458E-03 0,0716082 ! decidualization GO:0046697 11 5 0,000 6,458E-03 0,07127973 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 6,458E-03 0,07095425 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 6,458E-03 0,07063173 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 6,458E-03 0,07031213 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 6,458E-03 0,06999541 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 6,458E-03 0,06968153 ! base conversion or substitution editing GO:0016553 5 5 0,000 6,458E-03 0,06937045 ! neural tube patterning GO:0021532 7 5 0,000 6,458E-03 0,06906213 ! embryonic cleavage GO:0040016 6 5 0,000 6,458E-03 0,06875655 ! peroxisome fission GO:0016559 5 5 0,000 6,458E-03 0,06845366 ! histone demethylation GO:0016577 10 5 0,000 6,458E-03 0,06815342 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 6,458E-03 0,06785581 ! mitotic recombination GO:0006312 9 5 0,000 6,458E-03 0,06756078 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 6,458E-03 0,06726831 ! metaphase plate congression GO:0051310 7 5 0,000 6,458E-03 0,06697836 ! regulation of sterol transport GO:0032371 7 5 0,000 6,458E-03 0,0666909 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 6,458E-03 0,0664059 ! enteric nervous system development GO:0048484 8 5 0,000 6,458E-03 0,06612332 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 6,458E-03 0,06584314 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 6,458E-03 0,06556532 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 6,458E-03 0,06528983 ! muscle cell proliferation GO:0033002 11 5 0,000 6,458E-03 0,06501665 ! skeletal muscle regeneration GO:0043403 8 5 0,000 6,458E-03 0,06474575 ! plasminogen activation GO:0031639 5 5 0,000 6,458E-03 0,0644771 ! B cell homeostasis GO:0001782 13 5 0,000 6,458E-03 0,06421066 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 6,458E-03 0,06394642 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 6,458E-03 0,06368435 ! metaphase GO:0051323 8 5 0,000 6,458E-03 0,06342441 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 6,458E-03 0,06316659 ! cellular response to nutrient GO:0031670 8 5 0,000 6,458E-03 0,06291085 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 6,458E-03 0,06265718 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 6,458E-03 0,06240554 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 6,458E-03 0,06215592 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 6,458E-03 0,06190829 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 6,458E-03 0,06166262 ! response to redox state GO:0051775 5 5 0,000 6,458E-03 0,06141889 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 6,458E-03 0,06117709 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 6,458E-03 0,06093718 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,458E-03 0,06069914 ! regulation of telomerase activity GO:0051972 6 5 0,000 6,458E-03 0,06046296 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,458E-03 0,06022861 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 6,458E-03 0,05999606 ! porphyrin catabolic process GO:0006787 12 5 0,000 6,458E-03 0,05976531 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 6,458E-03 0,05953632 ! striatum development GO:0021756 9 5 0,000 6,458E-03 0,05930908 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 6,458E-03 0,05908358 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 6,458E-03 0,05885977 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 6,458E-03 0,05863766 ! glial cell migration GO:0008347 11 5 0,000 6,458E-03 0,05841722 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,458E-03 0,05819843 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 6,458E-03 0,05798127 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 6,458E-03 0,05776573 ! somatic stem cell maintenance GO:0035019 15 5 0,000 6,458E-03 0,05755178 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 6,458E-03 0,05733941 ! negative regulation of lipase activity GO:0060192 8 5 0,000 6,458E-03 0,0571286 ! neuroprotection GO:0043526 6 5 0,000 6,458E-03 0,05691934 ! neural plate development GO:0001840 8 5 0,000 6,458E-03 0,05671161 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 6,458E-03 0,05650538 ! regulation of sensory perception GO:0051931 7 5 0,000 6,458E-03 0,05630065 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 6,458E-03 0,0560974 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 6,458E-03 0,05589561 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 6,458E-03 0,05569527 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 6,458E-03 0,05549636 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 6,458E-03 0,05529886 ! sequestering of calcium ion GO:0051208 7 5 0,000 6,458E-03 0,05510277 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 6,458E-03 0,05490806 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 6,458E-03 0,05471472 ! spindle assembly GO:0051225 6 5 0,000 6,458E-03 0,05452274 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 6,458E-03 0,0543321 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 6,458E-03 0,05414279 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 6,458E-03 0,05395479 ! drug metabolic process GO:0017144 6 5 0,000 6,458E-03 0,0537681 ! stem cell division GO:0017145 11 5 0,000 6,458E-03 0,05358269 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 6,458E-03 0,05339856 ! organ regeneration GO:0031100 7 5 0,000 6,458E-03 0,05321569 ! carnitine metabolic process GO:0009437 7 5 0,000 6,458E-03 0,05303406 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 6,458E-03 0,05285367 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 6,458E-03 0,05267451 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 7,04E-03 0,05722334 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 7,745E-03 0,06274418 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 7,745E-03 0,06253363 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 7,745E-03 0,06232448 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 7,745E-03 0,06211674 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 7,745E-03 0,06191037 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 7,745E-03 0,06170537 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 7,745E-03 0,06150172 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 7,745E-03 0,06129941 ! sleep GO:0030431 13 6 0,000 7,745E-03 0,06109843 ! response to oxygen radical GO:0000305 11 6 0,000 7,745E-03 0,06089876 ! positive regulation of axon extension GO:0045773 11 6 0,000 7,745E-03 0,06070039 ! myoblast cell fate commitment GO:0048625 16 6 0,000 7,745E-03 0,06050331 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 7,745E-03 0,06030751 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 7,745E-03 0,06011297 ! regulation of interferon-beta production GO:0032648 8 6 0,000 7,745E-03 0,05991968 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 7,745E-03 0,05972763 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 7,745E-03 0,05953681 ! forebrain regionalization GO:0021871 8 6 0,000 7,745E-03 0,0593472 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 7,745E-03 0,0591588 ! male meiosis GO:0007140 7 6 0,000 7,745E-03 0,05897159 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 7,745E-03 0,05878556 ! response to zinc ion GO:0010043 9 6 0,000 7,745E-03 0,0586007 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 7,745E-03 0,05841699 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 7,745E-03 0,05823444 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 7,745E-03 0,05805302 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 7,745E-03 0,05787274 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 7,745E-03 0,05769356 ! malate metabolic process GO:0006108 11 6 0,000 7,745E-03 0,0575155 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 7,745E-03 0,05733853 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 7,745E-03 0,05716264 ! protein refolding GO:0042026 15 6 0,000 7,745E-03 0,05698783 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 7,745E-03 0,05681409 ! opsonization GO:0008228 8 6 0,000 7,745E-03 0,0566414 ! mating behavior GO:0007617 7 6 0,000 7,745E-03 0,05646976 ! neuron remodeling GO:0016322 15 6 0,000 7,745E-03 0,05629916 ! erythrocyte maturation GO:0043249 7 6 0,000 7,745E-03 0,05612958 ! embryonic hemopoiesis GO:0035162 14 6 0,000 7,745E-03 0,05596102 ! equilibrioception GO:0050957 14 6 0,000 7,745E-03 0,05579348 ! protein amino acid dealkylation GO:0008214 12 6 0,000 7,745E-03 0,05562693 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 7,745E-03 0,05546137 ! photoreceptor cell development GO:0042461 10 6 0,000 7,745E-03 0,0552968 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 7,745E-03 0,0551332 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 7,745E-03 0,05497056 ! response to interferon-gamma GO:0034341 15 6 0,000 7,745E-03 0,05480889 ! toxin metabolic process GO:0009404 11 6 0,000 7,745E-03 0,05464816 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 7,745E-03 0,05448837 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 7,745E-03 0,05432951 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 7,745E-03 0,05417157 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 7,745E-03 0,05401455 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 7,745E-03 0,05385844 ! cGMP-mediated signaling GO:0019934 13 6 0,000 7,745E-03 0,05370323 ! activation of MAPKKK activity GO:0000185 12 6 0,000 7,745E-03 0,05354891 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 7,745E-03 0,05339548 ! thymic T cell selection GO:0045061 12 6 0,000 7,745E-03 0,05324292 ! protein lipoylation GO:0009249 10 6 0,000 7,745E-03 0,05309123 ! cysteine metabolic process GO:0006534 10 6 0,000 7,745E-03 0,0529404 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 7,745E-03 0,05279043 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 7,745E-03 0,0526413 ! glutamate catabolic process GO:0006538 10 6 0,000 7,745E-03 0,05249302 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 7,745E-03 0,05234556 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 7,745E-03 0,05219894 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 7,745E-03 0,05205313 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 7,745E-03 0,05190814 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 7,745E-03 0,05176395 ! hyperosmotic response GO:0006972 9 6 0,000 7,745E-03 0,05162056 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 7,745E-03 0,05147796 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 7,745E-03 0,05133615 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 7,745E-03 0,05119511 ! urea metabolic process GO:0019627 7 6 0,000 7,745E-03 0,05105485 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 7,745E-03 0,05091536 ! neutrophil activation GO:0042119 8 6 0,000 7,745E-03 0,05077662 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 7,745E-03 0,05063864 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 7,745E-03 0,05050141 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 7,745E-03 0,05036492 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 7,745E-03 0,05022917 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 7,745E-03 0,05009414 ! neuron apoptosis GO:0051402 9 6 0,000 7,745E-03 0,04995984 ! nucleoside salvage GO:0043174 9 6 0,000 7,745E-03 0,04982626 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 7,745E-03 0,04969339 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 7,745E-03 0,04956123 ! T cell mediated immunity GO:0002456 16 6 0,000 7,745E-03 0,04942976 ! negative regulation of platelet activation GO:0010544 9 6 0,000 7,745E-03 0,049299 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 7,745E-03 0,04916892 ! carnitine transport GO:0015879 10 6 0,000 7,745E-03 0,04903953 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 7,745E-03 0,04891082 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,745E-03 0,04878278 ! positive regulation of exocytosis GO:0045921 8 6 0,000 7,745E-03 0,04865541 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 7,745E-03 0,0485287 ! 5S class rRNA transcription GO:0042791 11 6 0,000 7,745E-03 0,04840265 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 7,745E-03 0,04827726 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 7,745E-03 0,04815251 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 7,745E-03 0,0480284 ! sodium ion homeostasis GO:0055078 11 6 0,000 7,745E-03 0,04790494 ! establishment of spindle localization GO:0051293 12 6 0,000 7,745E-03 0,04778211 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 7,745E-03 0,0476599 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 7,745E-03 0,04753832 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 7,745E-03 0,04741736 ! neural nucleus development GO:0048857 14 6 0,000 7,745E-03 0,04729701 ! response to UV-C GO:0010225 11 6 0,000 7,745E-03 0,04717727 ! astrocyte development GO:0014002 15 6 0,000 7,745E-03 0,04705813 ! protein targeting to lysosome GO:0006622 10 6 0,000 7,745E-03 0,0469396 ! purine base biosynthetic process GO:0009113 17 6 0,000 7,745E-03 0,04682166 ! regulation of dendrite development GO:0050773 16 6 0,000 7,745E-03 0,04670431 ! skeletal muscle contraction GO:0003009 6 6 0,000 7,745E-03 0,04658755 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 7,745E-03 0,04647137 ! response to copper ion GO:0046688 10 6 0,000 7,745E-03 0,04635577 ! response to exogenous dsRNA GO:0043330 10 6 0,000 7,745E-03 0,04624075 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 7,745E-03 0,04612629 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,745E-03 0,0460124 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 7,745E-03 0,04589907 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 7,745E-03 0,04578629 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 7,745E-03 0,04567407 ! regulation of dopamine secretion GO:0014059 14 6 0,000 7,745E-03 0,0455624 ! nucleoside catabolic process GO:0009164 7 6 0,000 7,745E-03 0,04545127 ! hair follicle maturation GO:0048820 7 6 0,000 7,745E-03 0,04534068 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 7,745E-03 0,04523063 ! Schwann cell development GO:0014044 15 6 0,000 7,745E-03 0,04512112 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 7,745E-03 0,04501213 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 7,745E-03 0,04490367 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 7,745E-03 0,04479572 ! subpallium development GO:0021544 10 6 0,000 7,745E-03 0,0446883 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 7,745E-03 0,04458139 ! histone ubiquitination GO:0016574 8 6 0,000 7,745E-03 0,04447499 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 7,745E-03 0,0443691 ! maintenance of organ identity GO:0048496 9 6 0,000 7,745E-03 0,04426371 ! G2 phase GO:0051319 16 6 0,000 7,745E-03 0,04415882 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 7,745E-03 0,04405442 ! establishment of planar polarity GO:0001736 7 6 0,000 7,745E-03 0,04395052 ! regulation of mast cell activation GO:0033003 12 6 0,000 7,745E-03 0,04384711 ! membrane to membrane docking GO:0022614 14 6 0,000 7,745E-03 0,04374418 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 7,745E-03 0,04364174 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 7,745E-03 0,04353977 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 7,745E-03 0,04343828 ! receptor internalization GO:0031623 10 6 0,000 7,745E-03 0,04333726 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 7,745E-03 0,04323671 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 7,745E-03 0,04313662 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 7,745E-03 0,043037 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 7,745E-03 0,04293784 ! protein deubiquitination GO:0016579 14 6 0,000 7,745E-03 0,04283913 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 7,745E-03 0,04274087 ! protein destabilization GO:0031648 9 6 0,000 7,745E-03 0,04264307 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 7,745E-03 0,04254571 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 7,745E-03 0,0424488 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 7,745E-03 0,04235232 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 7,745E-03 0,04225628 ! progesterone metabolic process GO:0042448 10 6 0,000 7,745E-03 0,04216068 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 7,745E-03 0,04206551 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 7,745E-03 0,04197077 ! negative regulation of axon extension GO:0030517 21 6 0,000 7,745E-03 0,04187645 ! removal of superoxide radicals GO:0019430 11 6 0,000 7,745E-03 0,04178256 ! triglyceride catabolic process GO:0019433 10 6 0,000 7,745E-03 0,04168909 ! determination of adult lifespan GO:0008340 15 6 0,000 7,745E-03 0,04159603 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 7,745E-03 0,04150339 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 7,745E-03 0,04141116 ! cerebellar cortex formation GO:0021697 8 6 0,000 7,745E-03 0,04131934 ! catecholamine transport GO:0051937 9 6 0,000 7,745E-03 0,04122792 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 7,745E-03 0,04113691 ! sensory cilium assembly GO:0035058 10 6 0,000 7,745E-03 0,0410463 ! organ or tissue specific immune response GO:0002251 7 6 0,000 7,745E-03 0,04095609 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 7,745E-03 0,04086627 ! maternal placenta development GO:0001893 12 6 0,000 7,745E-03 0,04077685 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 7,745E-03 0,04068782 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 7,745E-03 0,04059917 ! negative regulation of B cell activation GO:0050869 13 6 0,000 7,745E-03 0,04051092 ! protein amino acid prenylation GO:0018346 16 6 0,000 7,745E-03 0,04042304 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 7,745E-03 0,04033554 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 7,745E-03 0,04024843 ! positive regulation of coagulation GO:0050820 12 6 0,000 7,745E-03 0,04016168 ! tRNA transcription GO:0009304 14 7 0,000 9,03E-03 0,04672506 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 9,03E-03 0,0466248 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 9,03E-03 0,04652496 ! behavioral response to cocaine GO:0048148 14 7 0,000 9,03E-03 0,04642554 ! regulation of helicase activity GO:0051095 15 7 0,000 9,03E-03 0,04632656 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 9,03E-03 0,04622799 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 9,03E-03 0,04612984 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 9,03E-03 0,04603211 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 9,03E-03 0,04593479 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 9,03E-03 0,04583788 ! prostate gland development GO:0030850 13 7 0,000 9,03E-03 0,04574138 ! nucleotide-sugar transport GO:0015780 12 7 0,000 9,03E-03 0,04564528 ! synaptonemal complex assembly GO:0007130 10 7 0,000 9,03E-03 0,04554959 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 9,03E-03 0,0454543 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 9,03E-03 0,0453594 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 9,03E-03 0,04526491 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 9,03E-03 0,0451708 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 9,03E-03 0,04507708 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 9,03E-03 0,04498376 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 9,03E-03 0,04489082 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 9,03E-03 0,04479826 ! SMAD protein complex assembly GO:0007183 12 7 0,000 9,03E-03 0,04470608 ! glycolipid transport GO:0046836 10 7 0,000 9,03E-03 0,04461428 ! protein amino acid sulfation GO:0006477 10 7 0,000 9,03E-03 0,04452286 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 9,03E-03 0,04443181 ! neuron adhesion GO:0007158 12 7 0,000 9,03E-03 0,04434113 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 9,03E-03 0,04425082 ! actin-myosin filament sliding GO:0033275 11 7 0,000 9,03E-03 0,04416088 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 9,03E-03 0,04407131 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 9,03E-03 0,04398209 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 9,03E-03 0,04389324 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 9,03E-03 0,04380475 ! mRNA stabilization GO:0048255 18 7 0,000 9,03E-03 0,04371661 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 9,03E-03 0,04362882 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 9,03E-03 0,04354139 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 9,03E-03 0,04345431 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 9,03E-03 0,04336757 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 9,03E-03 0,04328118 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 9,03E-03 0,04319514 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 9,03E-03 0,04310943 ! lipoprotein transport GO:0042953 14 7 0,000 9,03E-03 0,04302407 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 9,03E-03 0,04293904 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 9,03E-03 0,04285435 ! rhythmic behavior GO:0007622 15 7 0,000 9,03E-03 0,04276999 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 9,03E-03 0,04268596 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 9,03E-03 0,04260226 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 9,03E-03 0,04251889 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 9,03E-03 0,04243585 ! regulation of odontogenesis GO:0042481 13 7 0,000 9,03E-03 0,04235313 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 9,03E-03 0,04227073 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 9,03E-03 0,04218865 ! mechanosensory behavior GO:0007638 14 7 0,000 9,03E-03 0,04210689 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 9,03E-03 0,04202544 ! positive regulation of isotype switching GO:0045830 15 7 0,000 9,03E-03 0,04194431 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 9,03E-03 0,0418635 ! protein-cofactor linkage GO:0018065 13 7 0,000 9,03E-03 0,04178299 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 9,03E-03 0,04170279 ! spinal cord patterning GO:0021511 13 7 0,000 9,03E-03 0,0416229 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 9,03E-03 0,04154332 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 9,03E-03 0,04146404 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 9,03E-03 0,04138506 ! adrenal gland development GO:0030325 17 7 0,000 9,03E-03 0,04130638 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 9,03E-03 0,041228 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 9,03E-03 0,04114991 ! ovulation GO:0030728 9 7 0,000 9,03E-03 0,04107213 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 9,03E-03 0,04099463 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 9,03E-03 0,04091743 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 9,03E-03 0,04084052 ! microtubule nucleation GO:0007020 20 7 0,000 9,03E-03 0,04076389 ! proline biosynthetic process GO:0006561 10 7 0,000 9,03E-03 0,04068756 ! thyroid hormone generation GO:0006590 13 7 0,000 9,03E-03 0,0406115 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 9,03E-03 0,04053574 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 9,03E-03 0,04046025 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 9,03E-03 0,04038505 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 9,03E-03 0,04031012 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 9,03E-03 0,04023547 ! galactose metabolic process GO:0006012 13 7 0,000 9,03E-03 0,0401611 ! vesicle fusion GO:0006906 17 7 0,000 9,03E-03 0,040087 ! response to dietary excess GO:0002021 8 7 0,000 9,03E-03 0,04001318 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 9,03E-03 0,03993962 ! intracellular pH reduction GO:0051452 11 7 0,000 9,03E-03 0,03986634 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 9,03E-03 0,03979332 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 9,03E-03 0,03972058 ! organ growth GO:0035265 15 7 0,000 9,03E-03 0,03964809 ! purine salvage GO:0043101 10 7 0,000 9,03E-03 0,03957587 ! nucleoside transport GO:0015858 8 7 0,000 9,03E-03 0,03950392 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 9,03E-03 0,03943222 ! parturition GO:0007567 14 7 0,000 9,03E-03 0,03936079 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 9,03E-03 0,03928961 ! rRNA modification GO:0000154 14 7 0,000 9,03E-03 0,03921869 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 9,03E-03 0,03914803 ! spindle checkpoint GO:0031577 15 7 0,000 9,03E-03 0,03907762 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 9,03E-03 0,03900746 ! macrophage differentiation GO:0030225 11 7 0,000 9,03E-03 0,03893755 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 9,03E-03 0,0388679 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 9,03E-03 0,03879849 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 9,03E-03 0,03872933 ! hyaluronan metabolic process GO:0030212 8 7 0,000 9,03E-03 0,03866042 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 9,03E-03 0,03859175 ! anterograde axon cargo transport GO:0008089 18 7 0,000 9,03E-03 0,03852332 ! fibrinolysis GO:0042730 10 7 0,000 9,03E-03 0,03845514 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 9,03E-03 0,0383872 ! eating behavior GO:0042755 7 7 0,000 9,03E-03 0,0383195 ! B cell lineage commitment GO:0002326 21 7 0,000 9,03E-03 0,03825203 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 9,03E-03 0,03818481 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 9,03E-03 0,03811782 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 9,03E-03 0,03805106 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 9,03E-03 0,03798454 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 9,03E-03 0,03791825 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 9,03E-03 0,03785219 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 9,03E-03 0,03778636 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 9,03E-03 0,03772075 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 9,03E-03 0,03765538 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 9,03E-03 0,03759023 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 9,03E-03 0,03752531 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 9,03E-03 0,03746061 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 9,03E-03 0,03739614 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 9,03E-03 0,03733188 ! regulation of meiosis GO:0040020 12 7 0,000 9,03E-03 0,03726785 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 9,03E-03 0,03720403 ! T cell lineage commitment GO:0002360 16 7 0,000 9,03E-03 0,03714044 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 9,03E-03 0,03707706 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 9,03E-03 0,03701389 ! oxygen homeostasis GO:0032364 12 7 0,000 9,03E-03 0,03695094 ! transcription termination GO:0006353 13 7 0,000 9,03E-03 0,03688821 ! response to tumor cell GO:0002347 13 7 0,000 9,03E-03 0,03682569 ! regulation of respiratory burst GO:0060263 11 7 0,000 9,03E-03 0,03676337 ! coenzyme A metabolic process GO:0015936 12 7 0,000 9,03E-03 0,03670127 ! anaphase GO:0051322 17 7 0,000 9,03E-03 0,03663938 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 9,03E-03 0,0365777 ! axonal fasciculation GO:0007413 18 7 0,000 9,03E-03 0,03651623 ! negative regulation of nuclear division GO:0051784 14 7 0,000 9,03E-03 0,03645496 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 9,03E-03 0,03639389 ! peptidyl-threonine modification GO:0018210 25 7 0,000 9,03E-03 0,03633303 ! diuresis GO:0030146 12 7 0,000 9,03E-03 0,03627238 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 9,03E-03 0,03621192 ! thiamin metabolic process GO:0006772 7 7 0,000 9,03E-03 0,03615167 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 9,03E-03 0,03609162 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 9,03E-03 0,03603177 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 9,03E-03 0,03597211 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 9,03E-03 0,03591265 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 9,03E-03 0,03585339 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 9,03E-03 0,03579432 ! melanin biosynthetic process GO:0042438 8 7 0,000 9,03E-03 0,03573545 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 9,03E-03 0,03567677 ! dopamine biosynthetic process GO:0042416 18 7 0,000 9,03E-03 0,03561829 ! glycolipid catabolic process GO:0019377 15 7 0,000 9,03E-03 0,03555999 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 9,03E-03 0,03550189 ! lymph node development GO:0048535 10 7 0,000 9,03E-03 0,03544397 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 9,03E-03 0,03538625 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 9,03E-03 0,03532871 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 9,03E-03 0,03527135 ! endosome to lysosome transport GO:0008333 11 7 0,000 9,03E-03 0,03521419 ! protein modification by small protein removal GO:0070646 16 7 0,000 9,03E-03 0,03515721 ! adult feeding behavior GO:0008343 9 7 0,000 9,03E-03 0,03510041 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 9,03E-03 0,0350438 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 9,03E-03 0,03498737 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 9,03E-03 0,03493112 ! muscle adaptation GO:0043500 14 7 0,000 9,03E-03 0,03487505 ! embryonic heart tube development GO:0035050 10 7 0,000 9,03E-03 0,03481916 ! retina homeostasis GO:0001895 12 7 0,000 9,03E-03 0,03476345 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 9,03E-03 0,03470791 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 9,03E-03 0,03465256 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 9,03E-03 0,03459738 ! protein prenylation GO:0018342 18 7 0,000 9,03E-03 0,03454238 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 9,03E-03 0,03448755 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 9,03E-03 0,03443289 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 9,03E-03 0,03437841 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01031396 0,03920282 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01031396 0,03914099 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,01031396 0,03907935 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01031396 0,0390179 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01031396 0,03895665 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01031396 0,03889559 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01031396 0,03883472 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01031396 0,03877404 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01031396 0,03871355 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01031396 0,03865325 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01031396 0,03859313 ! meiotic prophase I GO:0007128 13 8 0,000 0,01031396 0,03853321 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01031396 0,03847347 ! oligopeptide transport GO:0006857 15 8 0,000 0,01031396 0,03841391 ! UTP metabolic process GO:0046051 8 8 0,000 0,01031396 0,03835454 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01031396 0,03829535 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01031396 0,03823634 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01031396 0,03817752 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01031396 0,03811887 ! succinate metabolic process GO:0006105 14 8 0,000 0,01031396 0,03806041 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01031396 0,03800212 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01031396 0,03794401 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01031396 0,03788609 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01031396 0,03782833 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01031396 0,03777075 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01031396 0,03771335 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01031396 0,03765612 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01031396 0,03759907 ! reflex GO:0060004 16 8 0,000 0,01031396 0,03754219 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01031396 0,03748548 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01031396 0,03742894 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01031396 0,03737257 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01031396 0,03731637 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01031396 0,03726034 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01031396 0,03720448 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01031396 0,03714878 ! pigment granule organization GO:0048753 16 8 0,000 0,01031396 0,03709325 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01031396 0,03703789 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01031396 0,03698269 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01031396 0,03692766 ! histidine metabolic process GO:0006547 16 8 0,000 0,01031396 0,03687279 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01031396 0,03681808 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01031396 0,03676353 ! glycine catabolic process GO:0006546 13 8 0,000 0,01031396 0,03670915 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01031396 0,03665493 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01031396 0,03660086 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01031396 0,03654696 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01031396 0,03649321 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01031396 0,03643963 ! melanin metabolic process GO:0006582 15 8 0,000 0,01031396 0,0363862 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01031396 0,03633292 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01031396 0,0362798 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01031396 0,03622684 ! macrophage activation GO:0042116 12 8 0,000 0,01031396 0,03617403 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01031396 0,03612138 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01031396 0,03606887 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01031396 0,03601653 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01031396 0,03596433 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01031396 0,03591228 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01031396 0,03586038 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01031396 0,03580864 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01031396 0,03575704 ! osteoblast development GO:0002076 16 8 0,000 0,01031396 0,03570559 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01031396 0,03565429 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01031396 0,03560314 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01031396 0,03555213 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01031396 0,03550127 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01031396 0,03545055 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01031396 0,03539998 ! response to UV-B GO:0010224 16 8 0,000 0,01031396 0,03534955 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01031396 0,03529927 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01031396 0,03524913 ! intermediate filament organization GO:0045109 12 8 0,000 0,01031396 0,03519913 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01031396 0,03514927 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01031396 0,03509956 ! cellular extravasation GO:0045123 12 8 0,000 0,01031396 0,03504998 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01031396 0,03500054 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01031396 0,03495125 ! response to antibiotic GO:0046677 11 8 0,000 0,01031396 0,03490209 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01031396 0,03485307 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01031396 0,03480419 ! DNA topological change GO:0006265 12 8 0,000 0,01031396 0,03475544 ! response to tropane GO:0014073 15 8 0,000 0,01031396 0,03470683 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01031396 0,03465836 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01031396 0,03461002 ! melanosome transport GO:0032402 13 8 0,000 0,01031396 0,03456182 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,01031396 0,03451375 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01031396 0,03446581 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01031396 0,03441801 ! mast cell activation GO:0045576 14 8 0,000 0,01031396 0,03437034 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01031396 0,0343228 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01031396 0,03427539 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01031396 0,03422812 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01031396 0,03418097 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01031396 0,03413396 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01031396 0,03408707 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01031396 0,03404031 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01031396 0,03399368 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01031396 0,03394718 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01031396 0,0339008 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01031396 0,03385455 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01031396 0,03380843 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01031396 0,03376243 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01031396 0,03371656 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01031396 0,03367081 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01031396 0,03362518 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01031396 0,03357968 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01031396 0,03353431 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01031396 0,03348905 ! hormone catabolic process GO:0042447 17 8 0,000 0,01031396 0,03344392 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01031396 0,0333989 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01031396 0,03335401 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01031396 0,03330924 ! ATP catabolic process GO:0006200 11 8 0,000 0,01031396 0,03326459 ! blastocyst growth GO:0001832 19 8 0,000 0,01031396 0,03322006 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01031396 0,03317565 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01031396 0,03313136 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01031396 0,03308718 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01031396 0,03304312 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01031396 0,03299918 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01031396 0,03295536 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01031396 0,03291165 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01031396 0,03286806 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01031396 0,03282458 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01031396 0,03278122 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01031396 0,03273798 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01031396 0,03269484 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01031396 0,03265182 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01031396 0,03260892 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01031396 0,03256612 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01031396 0,03252344 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01031396 0,03248087 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01159589 0,03647022 ! axon extension GO:0048675 15 9 0,000 0,01159589 0,03642261 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01159589 0,03637512 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01159589 0,03632776 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01159589 0,03628052 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01159589 0,0362334 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01159589 0,03618641 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01159589 0,03613953 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01159589 0,03609278 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01159589 0,03604615 ! phosphate transport GO:0006817 19 9 0,000 0,01159589 0,03599964 ! reproductive behavior GO:0019098 19 9 0,000 0,01159589 0,03595325 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01159589 0,03590697 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01159589 0,03586082 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01159589 0,03581479 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01159589 0,03576887 ! GTP metabolic process GO:0046039 9 9 0,000 0,01159589 0,03572307 ! RNA methylation GO:0001510 15 9 0,000 0,01159589 0,03567739 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01159589 0,03563183 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01159589 0,03558638 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01159589 0,03554104 ! artery development GO:0060840 24 9 0,000 0,01159589 0,03549583 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01159589 0,03545072 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01159589 0,03540574 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01159589 0,03536086 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01159589 0,0353161 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01159589 0,03527145 ! chemosensory behavior GO:0007635 20 9 0,000 0,01159589 0,03522692 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01159589 0,0351825 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01159589 0,03513819 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01159589 0,03509399 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01159589 0,0350499 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01159589 0,03500592 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01159589 0,03496205 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01159589 0,0349183 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01159589 0,03487465 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01159589 0,03483111 ! protein targeting to ER GO:0045047 22 9 0,000 0,01159589 0,03478768 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01159589 0,03474436 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01159589 0,03470114 ! T cell selection GO:0045058 23 9 0,000 0,01159589 0,03465804 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,01159589 0,03461504 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01159589 0,03457214 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01159589 0,03452936 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01159589 0,03448667 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01159589 0,0344441 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01159589 0,03440163 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01159589 0,03435926 ! mannose metabolic process GO:0006013 13 9 0,000 0,01159589 0,034317 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01159589 0,03427484 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01159589 0,03423278 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01159589 0,03419083 ! receptor clustering GO:0043113 18 9 0,000 0,01159589 0,03414898 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01159589 0,03410724 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01159589 0,03406559 ! ruffle organization GO:0031529 15 9 0,000 0,01159589 0,03402405 ! retinol metabolic process GO:0042572 18 9 0,000 0,01159589 0,03398261 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01159589 0,03394126 ! behavioral fear response GO:0001662 22 9 0,000 0,01159589 0,03390002 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01159589 0,03385888 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01159589 0,03381784 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01159589 0,0337769 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01159589 0,03373606 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01159589 0,03369531 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01159589 0,03365467 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01159589 0,03361412 ! segment specification GO:0007379 13 9 0,000 0,01159589 0,03357367 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01159589 0,03353332 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01159589 0,03349306 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01159589 0,0334529 ! response to amine stimulus GO:0014075 13 9 0,000 0,01159589 0,03341284 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01159589 0,03337287 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01159589 0,033333 ! erythrocyte development GO:0048821 15 9 0,000 0,01159589 0,03329322 ! gas homeostasis GO:0033483 16 9 0,000 0,01159589 0,03325354 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01159589 0,03321395 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01159589 0,03317446 ! renal water homeostasis GO:0003091 14 9 0,000 0,01159589 0,03313506 ! postreplication repair GO:0006301 22 9 0,000 0,01159589 0,03309575 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01159589 0,03305654 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01159589 0,03301742 ! icosanoid secretion GO:0032309 15 9 0,000 0,01159589 0,03297839 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01159589 0,03293946 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01159589 0,03290061 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01159589 0,03286186 ! regulation of cell division GO:0051302 15 9 0,000 0,01159589 0,0328232 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01159589 0,03278463 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01159589 0,03274615 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01159589 0,03270776 ! sterol catabolic process GO:0016127 11 9 0,000 0,01159589 0,03266946 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01159589 0,03263125 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01159589 0,03259313 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01159589 0,0325551 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01159589 0,03251716 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01159589 0,0324793 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01159589 0,03244153 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01159589 0,03240386 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01159589 0,03236626 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01159589 0,03232876 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01159589 0,03229134 ! purine base metabolic process GO:0006144 21 9 0,000 0,01159589 0,03225401 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01159589 0,03221677 ! pigment granule transport GO:0051904 17 9 0,000 0,01159589 0,03217961 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01159589 0,03214253 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01159589 0,03210555 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01159589 0,03206864 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01159589 0,03203182 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01159589 0,03199509 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01287621 0,03548701 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,01287621 0,03544641 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01287621 0,0354059 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01287621 0,03536548 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,01287621 0,03532515 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01287621 0,03528492 ! synapsis GO:0007129 13 10 0,000 0,01287621 0,03524478 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01287621 0,03520473 ! N-glycan processing GO:0006491 20 10 0,000 0,01287621 0,03516477 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01287621 0,0351249 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01287621 0,03508512 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01287621 0,03504543 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01287621 0,03500583 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01287621 0,03496632 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,01287621 0,0349269 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01287621 0,03488757 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01287621 0,03484832 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01287621 0,03480917 ! androgen metabolic process GO:0008209 17 10 0,000 0,01287621 0,0347701 ! phospholipid efflux GO:0033700 16 10 0,000 0,01287621 0,03473112 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01287621 0,03469223 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01287621 0,03465342 ! lung alveolus development GO:0048286 26 10 0,000 0,01287621 0,0346147 ! pathogenesis GO:0009405 13 10 0,000 0,01287621 0,03457607 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01287621 0,03453753 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01287621 0,03449906 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01287621 0,03446069 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01287621 0,0344224 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01287621 0,0343842 ! endoderm development GO:0007492 16 10 0,000 0,01287621 0,03434608 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01287621 0,03430804 ! arginine catabolic process GO:0006527 13 10 0,000 0,01287621 0,03427009 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01287621 0,03423222 ! proline metabolic process GO:0006560 13 10 0,000 0,01287621 0,03419444 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01287621 0,03415674 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01287621 0,03411912 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01287621 0,03408158 ! V(D)J recombination GO:0033151 28 10 0,000 0,01287621 0,03404413 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01287621 0,03400676 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01287621 0,03396947 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01287621 0,03393227 ! B cell proliferation GO:0042100 18 10 0,000 0,01287621 0,03389514 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01287621 0,0338581 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01287621 0,03382114 ! multicellular organism growth GO:0035264 18 10 0,000 0,01287621 0,03378425 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01287621 0,03374745 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01287621 0,03371073 ! epithelial cell development GO:0002064 20 10 0,000 0,01287621 0,03367409 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01287621 0,03363752 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01287621 0,03360104 ! macroautophagy GO:0016236 17 10 0,000 0,01287621 0,03356464 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01287621 0,03352831 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01287621 0,03349207 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01287621 0,0334559 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01287621 0,03341981 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01287621 0,03338379 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01287621 0,03334786 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01287621 0,033312 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01287621 0,03327622 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01287621 0,03324052 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01287621 0,03320489 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01287621 0,03316934 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01287621 0,03313386 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01287621 0,03309846 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01287621 0,03306314 ! response to dsRNA GO:0043331 20 10 0,000 0,01287621 0,03302789 ! DNA ligation GO:0006266 19 10 0,000 0,01287621 0,03299272 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01287621 0,03295762 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01287621 0,03292259 ! melanosome localization GO:0032400 16 10 0,000 0,01287621 0,03288764 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01287621 0,03285277 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01287621 0,03281797 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01287621 0,03278324 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01287621 0,03274858 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01287621 0,032714 ! mRNA cleavage GO:0006379 17 10 0,000 0,01287621 0,03267949 ! protein sumoylation GO:0016925 15 10 0,000 0,01287621 0,03264506 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01287621 0,03261069 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01287621 0,0325764 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01287621 0,03254219 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01287621 0,03250804 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01287621 0,03247396 ! salivary gland development GO:0007431 27 10 0,000 0,01287621 0,03243996 ! prophase GO:0051324 15 10 0,000 0,01287621 0,03240603 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01287621 0,03237216 ! apical protein localization GO:0045176 15 10 0,000 0,01287621 0,03233837 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01287621 0,03230465 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01287621 0,032271 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01287621 0,03223742 ! midbrain development GO:0030901 13 10 0,000 0,01287621 0,03220391 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01287621 0,03217047 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01287621 0,0321371 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01287621 0,03210379 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01287621 0,03207056 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01287621 0,03203739 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01287621 0,0320043 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01287621 0,03197127 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01287621 0,03193831 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01287621 0,03190542 ! oocyte development GO:0048599 17 10 0,000 0,01287621 0,03187259 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01287621 0,03183984 ! blastocyst formation GO:0001825 17 10 0,000 0,01287621 0,03180715 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01287621 0,03177452 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01287621 0,03174197 ! activation of innate immune response GO:0002218 12 10 0,000 0,01287621 0,03170948 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01287621 0,03167706 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01287621 0,0316447 ! response to nicotine GO:0035094 20 10 0,000 0,01287621 0,03161241 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01287621 0,03158018 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01287621 0,03154802 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01287621 0,03151593 ! localization within membrane GO:0051668 20 10 0,000 0,01287621 0,0314839 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01415491 0,03457534 ! respiratory burst GO:0045730 17 11 0,000 0,01415491 0,03454028 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01415491 0,03450528 ! neuron fate specification GO:0048665 17 11 0,000 0,01415491 0,03447036 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01415491 0,0344355 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01415491 0,03440072 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01415491 0,03436601 ! thyroid gland development GO:0030878 26 11 0,000 0,01415491 0,03433136 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01415491 0,03429679 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01415491 0,03426229 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01415491 0,03422785 ! response to pain GO:0048265 24 11 0,000 0,01415491 0,03419349 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01415491 0,03415919 ! T cell proliferation GO:0042098 26 11 0,000 0,01415491 0,03412496 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01415491 0,0340908 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01415491 0,03405671 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01415491 0,03402269 ! bone resorption GO:0045453 16 11 0,000 0,01415491 0,03398874 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01415491 0,03395485 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01415491 0,03392103 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01415491 0,03388728 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01415491 0,03385359 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01415491 0,03381997 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01415491 0,03378642 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01415491 0,03375294 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01415491 0,03371952 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01415491 0,03368617 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01415491 0,03365288 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01415491 0,03361966 ! lipid digestion GO:0044241 18 11 0,000 0,01415491 0,0335865 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01415491 0,03355341 ! UV protection GO:0009650 19 11 0,000 0,01415491 0,03352039 ! adult heart development GO:0007512 14 11 0,000 0,01415491 0,03348743 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01415491 0,03345453 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01415491 0,0334217 ! temperature homeostasis GO:0001659 17 11 0,000 0,01415491 0,03338893 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01415491 0,03335623 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01415491 0,03332359 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01415491 0,03329102 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01415491 0,03325851 ! regulation of organ growth GO:0046620 13 11 0,000 0,01415491 0,03322606 ! pigment granule localization GO:0051875 20 11 0,000 0,01415491 0,03319368 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01415491 0,03316136 ! vasoconstriction GO:0042310 18 11 0,000 0,01415491 0,0331291 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01415491 0,0330969 ! embryonic axis specification GO:0000578 18 11 0,000 0,01415491 0,03306477 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01415491 0,0330327 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01415491 0,03300069 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01415491 0,03296874 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01415491 0,03293686 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01415491 0,03290504 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01415491 0,03287327 ! zymogen activation GO:0031638 15 11 0,000 0,01415491 0,03284157 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01415491 0,03280994 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01415491 0,03277836 ! nucleosome positioning GO:0016584 15 11 0,000 0,01415491 0,03274684 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01415491 0,03271538 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01415491 0,03268399 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01415491 0,03265265 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01415491 0,03262137 ! acid secretion GO:0046717 18 11 0,000 0,01415491 0,03259016 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01415491 0,032559 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01415491 0,0325279 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01415491 0,03249686 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01415491 0,03246588 ! oocyte differentiation GO:0009994 18 11 0,000 0,01415491 0,03243496 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01415491 0,0324041 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01415491 0,0323733 ! cholesterol efflux GO:0033344 19 11 0,000 0,01415491 0,03234256 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01415491 0,03231187 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01415491 0,03228124 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01415491 0,03225068 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01415491 0,03222016 ! embryonic gut development GO:0048566 15 11 0,000 0,01415491 0,03218971 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01415491 0,03215931 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01415491 0,03212897 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01415491 0,03209869 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01415491 0,03206847 ! defense response to fungus GO:0050832 13 11 0,000 0,01415491 0,0320383 ! developmental induction GO:0031128 19 11 0,000 0,01415491 0,03200819 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01415491 0,03197813 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01415491 0,03194814 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01415491 0,03191819 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01415491 0,03188831 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01415491 0,03185848 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01415491 0,0318287 ! nucleus localization GO:0051647 19 11 0,000 0,01415491 0,03179898 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01415491 0,03176932 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,015432 0,03460334 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,015432 0,03457112 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,015432 0,03453896 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,015432 0,03450686 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,015432 0,03447482 ! virus-host interaction GO:0019048 29 12 0,000 0,015432 0,03444284 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,015432 0,03441092 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,015432 0,03437906 ! cartilage condensation GO:0001502 20 12 0,000 0,015432 0,03434725 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,015432 0,03431551 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,015432 0,03428382 ! protein complex disassembly GO:0043241 27 12 0,000 0,015432 0,0342522 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,015432 0,03422063 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,015432 0,03418912 ! hippocampus development GO:0021766 26 12 0,000 0,015432 0,03415767 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,015432 0,03412627 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,015432 0,03409493 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,015432 0,03406365 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,015432 0,03403243 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,015432 0,03400127 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,015432 0,03397016 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,015432 0,03393911 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,015432 0,03390811 ! drug transport GO:0015893 16 12 0,000 0,015432 0,03387717 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,015432 0,03384629 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,015432 0,03381547 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,015432 0,0337847 ! polyamine metabolic process GO:0006595 17 12 0,000 0,015432 0,03375398 ! focal adhesion formation GO:0048041 35 12 0,000 0,015432 0,03372333 ! mitotic spindle organization GO:0007052 21 12 0,000 0,015432 0,03369272 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,015432 0,03366218 ! forebrain cell migration GO:0021885 21 12 0,000 0,015432 0,03363169 ! asymmetric protein localization GO:0008105 20 12 0,000 0,015432 0,03360125 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,015432 0,03357087 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,015432 0,03354054 ! entry into host cell GO:0030260 32 12 0,000 0,015432 0,03351027 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,015432 0,03348006 ! monoamine transport GO:0015844 18 12 0,000 0,015432 0,03344989 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,015432 0,03341979 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,015432 0,03338973 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,015432 0,03335973 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,015432 0,03332979 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,015432 0,03329989 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,015432 0,03327006 ! protein homotetramerization GO:0051289 21 12 0,000 0,015432 0,03324027 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,015432 0,03321054 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,015432 0,03318086 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,015432 0,03315123 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,015432 0,03312166 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,015432 0,03309214 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,015432 0,03306267 ! cranial nerve development GO:0021545 20 12 0,000 0,015432 0,03303326 ! fucose catabolic process GO:0019317 22 12 0,000 0,015432 0,0330039 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,015432 0,03297458 ! histone acetylation GO:0016573 26 12 0,000 0,015432 0,03294533 ! histone methylation GO:0016571 26 12 0,000 0,015432 0,03291612 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,015432 0,03288696 ! autonomic nervous system development GO:0048483 24 12 0,000 0,015432 0,03285786 ! gland morphogenesis GO:0022612 29 12 0,000 0,015432 0,03282881 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,015432 0,03279981 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,015432 0,03277086 ! T cell homeostasis GO:0043029 25 12 0,000 0,015432 0,03274196 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,015432 0,03271311 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,015432 0,03268432 ! spleen development GO:0048536 22 12 0,000 0,015432 0,03265557 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,015432 0,03262687 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,015432 0,03259823 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,015432 0,03256963 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,015432 0,03254109 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,015432 0,03251259 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,015432 0,03248415 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,015432 0,03245575 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,015432 0,03242741 ! response to cold GO:0009409 17 12 0,000 0,015432 0,03239911 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,015432 0,03237087 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,015432 0,03234267 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01670747 0,03498536 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01670747 0,03495493 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01670747 0,03492456 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01670747 0,03489425 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01670747 0,03486398 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01670747 0,03483377 ! lipid localization GO:0010876 28 13 0,000 0,01670747 0,03480361 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01670747 0,03477351 ! organelle fusion GO:0048284 32 13 0,000 0,01670747 0,03474345 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01670747 0,03471345 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01670747 0,0346835 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01670747 0,0346536 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01670747 0,03462375 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01670747 0,03459395 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01670747 0,03456421 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01670747 0,03453451 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01670747 0,03450487 ! methionine metabolic process GO:0006555 27 13 0,000 0,01670747 0,03447528 ! plasma membrane organization GO:0007009 24 13 0,000 0,01670747 0,03444574 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01670747 0,03441624 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01670747 0,0343868 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01670747 0,03435741 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01670747 0,03432807 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01670747 0,03429878 ! response to X-ray GO:0010165 25 13 0,000 0,01670747 0,03426954 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01670747 0,03424035 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01670747 0,03421121 ! exocrine system development GO:0035272 32 13 0,000 0,01670747 0,03418212 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01670747 0,03415308 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01670747 0,03412409 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01670747 0,03409514 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01670747 0,03406625 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01670747 0,0340374 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01670747 0,03400861 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01670747 0,03397986 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01670747 0,03395116 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01670747 0,03392251 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01670747 0,03389391 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01670747 0,03386535 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01670747 0,03383685 ! ribosome assembly GO:0042255 17 13 0,000 0,01670747 0,03380839 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01670747 0,03377998 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01670747 0,03375161 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,01670747 0,0337233 ! chromatin silencing GO:0006342 26 13 0,000 0,01670747 0,03369503 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01670747 0,03366681 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01670747 0,03363864 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01670747 0,03361051 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01670747 0,03358243 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01670747 0,0335544 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01670747 0,03352642 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01670747 0,03349848 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01670747 0,03347059 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01670747 0,03344274 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01670747 0,03341494 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01670747 0,03338719 ! embryonic placenta development GO:0001892 23 13 0,000 0,01670747 0,03335948 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01670747 0,03333182 ! insulin secretion GO:0030073 23 13 0,000 0,01670747 0,0333042 ! actin filament polymerization GO:0030041 24 13 0,000 0,01670747 0,03327663 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01670747 0,03324911 ! acrosome reaction GO:0007340 18 13 0,000 0,01670747 0,03322163 ! rRNA transcription GO:0009303 25 14 0,000 0,01798133 0,0357251 ! lactation GO:0007595 26 14 0,000 0,01798133 0,03569562 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01798133 0,03566619 ! reproductive cellular process GO:0048610 20 14 0,000 0,01798133 0,03563681 ! tRNA modification GO:0006400 20 14 0,000 0,01798133 0,03560748 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01798133 0,0355782 ! regulation of S phase GO:0033261 23 14 0,000 0,01798133 0,03554897 ! water transport GO:0006833 21 14 0,000 0,01798133 0,03551978 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01798133 0,03549064 ! non-recombinational repair GO:0000726 25 14 0,000 0,01798133 0,03546155 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,01798133 0,03543251 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01798133 0,03540351 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01798133 0,03537456 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01798133 0,03534566 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01798133 0,03531681 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01798133 0,035288 ! palate development GO:0060021 31 14 0,000 0,01798133 0,03525924 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01798133 0,03523053 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01798133 0,03520186 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01798133 0,03517324 ! arginine metabolic process GO:0006525 17 14 0,000 0,01798133 0,03514467 ! regulation of heart rate GO:0002027 24 14 0,000 0,01798133 0,03511615 ! organic alcohol transport GO:0015850 29 14 0,000 0,01798133 0,03508766 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01798133 0,03505923 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,01798133 0,03503084 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01798133 0,0350025 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01798133 0,0349742 ! L-amino acid transport GO:0015807 30 14 0,000 0,01798133 0,03494595 ! bone mineralization GO:0030282 17 14 0,000 0,01798133 0,03491775 ! stem cell development GO:0048864 43 14 0,000 0,01798133 0,03488959 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01798133 0,03486148 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01798133 0,03483341 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01798133 0,03480538 ! cerebellum development GO:0021549 21 14 0,000 0,01798133 0,0347774 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01798133 0,03474947 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01798133 0,03472158 ! response to gamma radiation GO:0010332 28 14 0,000 0,01798133 0,03469374 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01798133 0,03466594 ! cofactor transport GO:0051181 26 14 0,000 0,01798133 0,03463818 ! NADP metabolic process GO:0006739 24 14 0,000 0,01798133 0,03461047 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01798133 0,03458281 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01798133 0,03455518 ! intestinal absorption GO:0050892 25 14 0,000 0,01798133 0,03452761 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01798133 0,03450007 ! oxygen transport GO:0015671 21 14 0,000 0,01798133 0,03447258 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01798133 0,03444514 ! male genitalia development GO:0030539 24 14 0,000 0,01798133 0,03441773 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01798133 0,03439037 ! regulation of axon extension GO:0030516 37 14 0,000 0,01798133 0,03436306 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,01798133 0,03433579 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01798133 0,03430856 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01925359 0,03670692 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01925359 0,03667786 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,01925359 0,03664884 ! superoxide anion generation GO:0042554 20 15 0,000 0,01925359 0,03661987 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01925359 0,03659095 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01925359 0,03656207 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01925359 0,03653323 ! copper ion transport GO:0006825 20 15 0,000 0,01925359 0,03650444 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01925359 0,0364757 ! sulfate transport GO:0008272 23 15 0,000 0,01925359 0,036447 ! response to cAMP GO:0051591 22 15 0,000 0,01925359 0,03641835 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01925359 0,03638974 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01925359 0,03636118 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01925359 0,03633266 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01925359 0,03630418 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01925359 0,03627576 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01925359 0,03624737 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01925359 0,03621903 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01925359 0,03619073 ! pituitary gland development GO:0021983 29 15 0,000 0,01925359 0,03616248 ! vesicle coating GO:0006901 33 15 0,000 0,01925359 0,03613427 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01925359 0,03610611 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01925359 0,03607799 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01925359 0,03604991 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01925359 0,03602188 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01925359 0,03599389 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01925359 0,03596595 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01925359 0,03593804 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01925359 0,03591019 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01925359 0,03588237 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01925359 0,0358546 ! histone deacetylation GO:0016575 20 15 0,000 0,01925359 0,03582687 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01925359 0,03579918 ! tissue regeneration GO:0042246 26 15 0,000 0,01925359 0,03577154 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01925359 0,03574393 ! water homeostasis GO:0030104 27 15 0,000 0,01925359 0,03571638 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01925359 0,03568886 ! muscle maintenance GO:0046716 26 15 0,000 0,01925359 0,03566139 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01925359 0,03563395 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01925359 0,03560656 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01925359 0,03557922 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01925359 0,03555191 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01925359 0,03552465 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,01925359 0,03549742 ! detection of bacterium GO:0016045 18 15 0,000 0,01925359 0,03547024 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01925359 0,03544311 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01925359 0,03541601 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01925359 0,03538895 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01925359 0,03536194 ! peptide hormone processing GO:0016486 23 15 0,000 0,01925359 0,03533497 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,02052424 0,0376382 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02052424 0,03760954 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,02052424 0,03758092 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02052424 0,03755234 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02052424 0,0375238 ! bone remodeling GO:0046849 27 16 0,000 0,02052424 0,03749531 ! filopodium assembly GO:0046847 32 16 0,000 0,02052424 0,03746686 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02052424 0,03743846 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02052424 0,03741009 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02052424 0,03738177 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02052424 0,0373535 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,02052424 0,03732526 ! startle response GO:0001964 28 16 0,000 0,02052424 0,03729707 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02052424 0,03726892 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,02052424 0,03724082 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02052424 0,03721275 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,02052424 0,03718473 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02052424 0,03715675 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,02052424 0,03712881 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02052424 0,03710092 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02052424 0,03707307 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,02052424 0,03704525 ! response to osmotic stress GO:0006970 25 16 0,000 0,02052424 0,03701748 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,02052424 0,03698976 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,02052424 0,03696207 ! fructose metabolic process GO:0006000 25 16 0,000 0,02052424 0,03693442 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02052424 0,03690682 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02052424 0,03687926 ! intermediate filament-based process GO:0045103 32 16 0,000 0,02052424 0,03685173 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,02052424 0,03682425 ! negative regulation of immune response GO:0050777 35 16 0,000 0,02052424 0,03679681 ! axon cargo transport GO:0008088 43 16 0,000 0,02052424 0,03676941 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02052424 0,03674206 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02052424 0,03671474 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,02052424 0,03668746 ! DNA replication initiation GO:0006270 27 16 0,000 0,02052424 0,03666023 ! neuron recognition GO:0008038 35 16 0,000 0,02052424 0,03663303 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02052424 0,03660587 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02052424 0,03657876 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02052424 0,03655168 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,02052424 0,03652465 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,02052424 0,03649765 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02052424 0,0364707 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,02052424 0,03644378 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02052424 0,03641691 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02052424 0,03639007 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02052424 0,03636327 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02052424 0,03633651 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02052424 0,0363098 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02052424 0,03628312 ! defense response to virus GO:0051607 37 16 0,000 0,02052424 0,03625648 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,02179329 0,03847003 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,02179329 0,03844182 ! metencephalon development GO:0022037 30 17 0,000 0,02179329 0,03841366 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,02179329 0,03838554 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,02179329 0,03835746 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,02179329 0,03832942 ! signal complex assembly GO:0007172 41 17 0,000 0,02179329 0,03830142 ! endothelial cell migration GO:0043542 28 17 0,000 0,02179329 0,03827347 ! inositol metabolic process GO:0006020 28 17 0,000 0,02179329 0,03824555 ! gene silencing by RNA GO:0031047 36 17 0,000 0,02179329 0,03821767 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,02179329 0,03818984 ! glial cell development GO:0021782 27 17 0,000 0,02179329 0,03816204 ! limbic system development GO:0021761 36 17 0,000 0,02179329 0,03813429 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,02179329 0,03810658 ! adult walking behavior GO:0007628 33 17 0,000 0,02179329 0,0380789 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,02179329 0,03805127 ! heart looping GO:0001947 30 17 0,000 0,02179329 0,03802368 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,02179329 0,03799612 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,02179329 0,03796861 ! myoblast differentiation GO:0045445 45 17 0,000 0,02179329 0,03794113 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,02179329 0,0379137 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,02179329 0,03788631 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,02179329 0,03785895 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,02179329 0,03783164 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02179329 0,03780436 ! glycine metabolic process GO:0006544 28 17 0,000 0,02179329 0,03777712 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,02179329 0,03774993 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02179329 0,03772277 ! NAD metabolic process GO:0019674 29 17 0,000 0,02179329 0,03769565 ! membrane budding GO:0006900 37 17 0,000 0,02179329 0,03766857 ! DNA integration GO:0015074 29 17 0,000 0,02179329 0,03764153 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,02179329 0,03761453 ! regulation of protein binding GO:0043393 33 17 0,000 0,02179329 0,03758756 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,02179329 0,03756064 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,02179329 0,03753375 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,02179329 0,0375069 ! genitalia development GO:0048806 30 17 0,000 0,02179329 0,03748009 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,02179329 0,03745332 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,02179329 0,03742659 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,02179329 0,03739989 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,02179329 0,03737323 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,02179329 0,03734662 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,02179329 0,03732003 ! steroid catabolic process GO:0006706 31 17 0,000 0,02179329 0,03729349 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,02179329 0,03726699 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,02179329 0,03724052 ! gas transport GO:0015669 25 17 0,000 0,02179329 0,03721409 ! organic cation transport GO:0015695 31 17 0,000 0,02179329 0,03718769 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,02179329 0,03716134 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,02179329 0,03713502 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,02179329 0,03710874 ! microspike assembly GO:0030035 36 17 0,000 0,02179329 0,0370825 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,02179329 0,03705629 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,02179329 0,03703012 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,02306073 0,03915605 ! neuron maturation GO:0042551 42 18 0,000 0,02306073 0,03912843 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,02306073 0,03910086 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,02306073 0,03907332 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,02306073 0,03904583 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,02306073 0,03901837 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,02306073 0,03899095 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,02306073 0,03896357 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02306073 0,03893622 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,02306073 0,03890892 ! patterning of blood vessels GO:0001569 39 18 0,000 0,02306073 0,03888165 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,02306073 0,03885442 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,02306073 0,03882723 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,02306073 0,03880008 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,02306073 0,03877297 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02306073 0,03874589 ! response to retinoic acid GO:0032526 26 18 0,000 0,02306073 0,03871885 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,02306073 0,03869185 ! response to fungus GO:0009620 21 18 0,000 0,02306073 0,03866489 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,02306073 0,03863797 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,02306073 0,03861108 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,02306073 0,03858423 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,02306073 0,03855741 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,02306073 0,03853064 ! vitamin transport GO:0051180 27 18 0,000 0,02306073 0,0385039 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,02306073 0,0384772 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,02306073 0,03845053 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,02306073 0,0384239 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,02306073 0,03839731 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,02306073 0,03837076 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,02306073 0,03834424 ! nerve development GO:0021675 28 18 0,000 0,02306073 0,03831776 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,02306073 0,03829132 ! protein secretion GO:0009306 39 19 0,000 0,02432657 0,04036534 ! positive regulation of translation GO:0045727 30 19 0,000 0,02432657 0,04033752 ! negative regulation of defense response GO:0031348 25 19 0,000 0,02432657 0,04030974 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,02432657 0,04028199 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,02432657 0,04025429 ! skin development GO:0043588 36 19 0,000 0,02432657 0,04022662 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,02432657 0,040199 ! lipid phosphorylation GO:0046834 35 19 0,000 0,02432657 0,04017141 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02432657 0,04014385 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,02432657 0,04011634 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,02432657 0,04008886 ! bile acid metabolic process GO:0008206 29 19 0,000 0,02432657 0,04006142 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,02432657 0,04003402 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,02432657 0,04000666 ! cerebral cortex development GO:0021987 36 19 0,000 0,02432657 0,03997933 ! pigmentation during development GO:0048066 41 19 0,000 0,02432657 0,03995204 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,02432657 0,03992479 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,02432657 0,03989757 ! heme metabolic process GO:0042168 36 19 0,000 0,02432657 0,03987039 ! actin filament bundle formation GO:0051017 42 19 0,000 0,02432657 0,03984325 ! neuromuscular junction development GO:0007528 34 19 0,000 0,02432657 0,03981615 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,02432657 0,03978908 ! plasma membrane fusion GO:0045026 28 19 0,000 0,02432657 0,03976205 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,02432657 0,03973506 ! peptide cross-linking GO:0018149 37 19 0,000 0,02432657 0,0397081 ! protein export from nucleus GO:0006611 36 19 0,000 0,02432657 0,03968118 ! heart process GO:0003015 30 19 0,000 0,02432657 0,03965429 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,02432657 0,03962745 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,02432657 0,03960063 ! visual learning GO:0008542 36 19 0,000 0,02432657 0,03957386 ! cellular pigmentation GO:0033059 36 19 0,000 0,02432657 0,03954712 ! G1 phase GO:0051318 40 19 0,000 0,02432657 0,03952042 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,02432657 0,03949375 ! cell-cell junction organization GO:0045216 35 19 0,000 0,02432657 0,03946712 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,02432657 0,03944052 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,02432657 0,03941397 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,02432657 0,03938744 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,02432657 0,03936095 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,02432657 0,0393345 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,02432657 0,03930808 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,02432657 0,0392817 ! cilium assembly GO:0042384 37 19 0,000 0,02432657 0,03925536 ! peptide hormone secretion GO:0030072 31 19 0,000 0,02432657 0,03922905 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,02559082 0,04124013 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,02559082 0,04121253 ! positive regulation of ossification GO:0045778 47 20 0,000 0,02559082 0,04118496 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,02559082 0,04115743 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,02559082 0,04112994 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,02559082 0,04110248 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,02559082 0,04107506 ! cAMP metabolic process GO:0046058 36 20 0,000 0,02559082 0,04104768 ! response to vitamin GO:0033273 31 20 0,000 0,02559082 0,04102033 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,02559082 0,04099302 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,02559082 0,04096574 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,02559082 0,04093851 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,02559082 0,0409113 ! response to alkaloid GO:0043279 38 20 0,000 0,02559082 0,04088414 ! retinoid metabolic process GO:0001523 32 20 0,000 0,02559082 0,04085701 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,02559082 0,04082992 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,02559082 0,04080286 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,02559082 0,04077584 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,02559082 0,04074885 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,02559082 0,0407219 GO:0032392|DNA geometric change, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,02559082 0,04069499 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,02559082 0,04066811 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,02559082 0,04064126 ! body fluid secretion GO:0007589 31 20 0,000 0,02559082 0,04061445 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,02559082 0,04058768 ! peptide secretion GO:0002790 35 20 0,000 0,02559082 0,04056094 ! stem cell differentiation GO:0048863 53 20 0,000 0,02559082 0,04053424 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,02559082 0,04050757 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,02559082 0,04048094 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,02559082 0,04045435 ! sensory perception of pain GO:0019233 30 20 0,000 0,02559082 0,04042778 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,02559082 0,04040126 ! diencephalon development GO:0021536 34 20 0,000 0,02559082 0,04037476 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,02559082 0,0403483 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,02559082 0,04032188 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,02559082 0,04029549 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,02559082 0,04026914 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,02559082 0,04024282 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,02559082 0,04021653 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,02559082 0,04019028 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,02559082 0,04016407 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,02559082 0,04013788 ! regulation of glucose import GO:0046324 29 20 0,000 0,02559082 0,04011173 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,02559082 0,04008562 ! actin filament-based movement GO:0030048 43 20 0,000 0,02559082 0,04005954 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,02559082 0,04003349 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,02559082 0,04000748 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,02559082 0,0399815 ! negative regulation of translation GO:0017148 29 20 0,000 0,02559082 0,03995556 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,02559082 0,03992965 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,02559082 0,03990377 ! regulation of cell killing GO:0031341 42 21 0,000 0,02685347 0,0418455 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,02685347 0,04181841 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,02685347 0,04179136 ! hormone secretion GO:0046879 38 21 0,000 0,02685347 0,04176435 ! glycerol metabolic process GO:0006071 34 21 0,000 0,02685347 0,04173737 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,02685347 0,04171042 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,02685347 0,04168351 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,02685347 0,04165664 ! axis specification GO:0009798 38 21 0,000 0,02685347 0,0416298 ! ovarian follicle development GO:0001541 35 21 0,000 0,02685347 0,04160299 ! smooth muscle contraction GO:0006939 46 21 0,000 0,02685347 0,04157622 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,02685347 0,04154948 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,02685347 0,04152278 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,02685347 0,04149611 ! cell aging GO:0007569 44 21 0,000 0,02685347 0,04146948 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,02685347 0,04144288 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,02685347 0,04141631 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,02685347 0,04138978 ! cytolysis GO:0019835 24 21 0,000 0,02685347 0,04136328 ! vasodilation GO:0042311 39 21 0,000 0,02685347 0,04133682 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,02685347 0,04131039 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,02685347 0,04128399 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,02685347 0,04125763 ! oogenesis GO:0048477 36 21 0,000 0,02685347 0,0412313 ! DNA modification GO:0006304 34 21 0,000 0,02685347 0,041205 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,02685347 0,04117874 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,02685347 0,04115251 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,02685347 0,04112632 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,02685347 0,04110016 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,02685347 0,04107403 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,02685347 0,04104793 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,02685347 0,04102187 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,02685347 0,04099584 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,02685347 0,04096985 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,02685347 0,04094388 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,02685347 0,04091795 ! collagen catabolic process GO:0030574 28 21 0,000 0,02685347 0,04089206 ! sperm-egg recognition GO:0035036 21 21 0,000 0,02685347 0,04086619 ! gut development GO:0048565 39 21 0,000 0,02685347 0,04084036 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,02811452 0,04273124 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,02811452 0,04270426 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,02811452 0,04267732 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,02811452 0,04265041 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,02811452 0,04262353 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,02811452 0,04259669 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,02811452 0,04256988 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,02811452 0,04254311 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,02811452 0,04251637 ! regeneration GO:0031099 41 22 0,000 0,02811452 0,04248966 ! keratinization GO:0031424 28 22 0,000 0,02811452 0,04246299 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,02811452 0,04243635 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,02811452 0,04240975 ! sensory perception of taste GO:0050909 28 22 0,000 0,02811452 0,04238317 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,02811452 0,04235664 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,02811452 0,04233013 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,02811452 0,04230366 ! vacuolar transport GO:0007034 36 22 0,000 0,02811452 0,04227722 ! lysosome organization GO:0007040 41 22 0,000 0,02811452 0,04225081 ! central nervous system neuron development GO:0021954 46 22 0,000 0,02811452 0,04222444 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,02811452 0,04219809 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,02811452 0,04217179 ! fucose metabolic process GO:0006004 39 22 0,000 0,02811452 0,04214551 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,02811452 0,04211927 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,02811452 0,04209306 ! ureteric bud development GO:0001657 43 22 0,000 0,02811452 0,04206688 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,02811452 0,04204074 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,02811452 0,04201462 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,02811452 0,04198855 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,02811452 0,0419625 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,02811452 0,04193648 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,02811452 0,0419105 ! sarcomere organization GO:0045214 30 22 0,000 0,02811452 0,04188455 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,02811452 0,04185863 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,02811452 0,04183274 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,02811452 0,04180689 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,02811452 0,04178107 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,02811452 0,04175528 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,02811452 0,04172952 ! protein stabilization GO:0050821 39 22 0,000 0,02811452 0,04170379 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,02937399 0,04354517 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,02937399 0,04351836 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,02937399 0,04349158 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,02937399 0,04346483 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,02937399 0,04343812 ! gluconeogenesis GO:0006094 33 23 0,000 0,02937399 0,04341143 ! viral genome replication GO:0019079 41 23 0,000 0,02937399 0,04338478 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,02937399 0,04335817 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,02937399 0,04333158 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,02937399 0,04330503 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,02937399 0,04327851 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,02937399 0,04325203 ! visual behavior GO:0007632 42 23 0,000 0,02937399 0,04322557 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,02937399 0,04319915 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,02937399 0,04317276 ! response to ethanol GO:0045471 46 23 0,000 0,02937399 0,04314641 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,02937399 0,04312008 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,02937399 0,04309379 ! peroxisome organization GO:0007031 37 23 0,000 0,02937399 0,04306753 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,02937399 0,0430413 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,02937399 0,0430151 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,02937399 0,04298894 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,02937399 0,0429628 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,02937399 0,0429367 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,02937399 0,04291063 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,02937399 0,0428846 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,02937399 0,04285859 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,02937399 0,04283261 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,02937399 0,04280667 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,02937399 0,04278076 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,02937399 0,04275488 ! fatty acid transport GO:0015908 44 23 0,000 0,02937399 0,04272903 ! platelet activation GO:0030168 37 23 0,000 0,02937399 0,04270321 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,02937399 0,04267742 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,02937399 0,04265167 ! hormone transport GO:0009914 40 23 0,000 0,02937399 0,04262594 ! cell-cell recognition GO:0009988 25 23 0,000 0,02937399 0,04260025 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,02937399 0,04257459 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,02937399 0,04254895 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,02937399 0,04252335 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,02937399 0,04249778 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,02937399 0,04247224 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,03063186 0,04426442 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,03063186 0,04423785 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,03063186 0,04421131 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,03063186 0,04418481 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,03063186 0,04415833 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,03063186 0,04413189 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,03063186 0,04410548 ! vesicle docking GO:0048278 47 24 0,000 0,03063186 0,0440791 ! spinal cord development GO:0021510 47 24 0,000 0,03063186 0,04405275 ! vacuole organization GO:0007033 43 24 0,000 0,03063186 0,04402644 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,03063186 0,04400015 ! digestive system process GO:0022600 39 24 0,000 0,03063186 0,0439739 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,03063186 0,04394768 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,03063186 0,04392149 ! regulation of behavior GO:0050795 43 24 0,000 0,03063186 0,04389533 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,03063186 0,0438692 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,03063186 0,0438431 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,03063186 0,04381704 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,03063186 0,043791 ! membrane depolarization GO:0051899 39 24 0,000 0,03063186 0,043765 ! pallium development GO:0021543 49 24 0,000 0,03063186 0,04373902 ! pentose metabolic process GO:0019321 35 24 0,000 0,03063186 0,04371308 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,03063186 0,04368717 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,03063186 0,04366129 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,03063186 0,04363544 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,03063186 0,04360962 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,03063186 0,04358383 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,03063186 0,04355807 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,03063186 0,04353234 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,03063186 0,04350664 ! regulation of amine transport GO:0051952 40 24 0,000 0,03063186 0,04348098 ! protein tetramerization GO:0051262 52 24 0,000 0,03063186 0,04345534 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,03188814 0,04521089 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,03188814 0,04518426 ! myelination GO:0042552 45 25 0,000 0,03188814 0,04515767 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,03188814 0,0451311 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,03188814 0,04510457 ! phototransduction GO:0007602 33 25 0,000 0,03188814 0,04507807 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,03188814 0,0450516 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,03188814 0,04502516 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,03188814 0,04499875 ! sperm motility GO:0030317 31 25 0,000 0,03188814 0,04497238 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,03188814 0,04494603 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,03188814 0,04491972 ! receptor metabolic process GO:0043112 46 25 0,000 0,03188814 0,04489343 ! chromosome condensation GO:0030261 45 25 0,000 0,03188814 0,04486718 ! osteoblast differentiation GO:0001649 60 25 0,000 0,03188814 0,04484096 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,03188814 0,04481476 ! neural crest cell development GO:0014032 54 25 0,000 0,03188814 0,0447886 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,03188814 0,04476247 ! negative regulation of cell development GO:0010721 73 25 0,000 0,03188814 0,04473637 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,03188814 0,0447103 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,03188814 0,04468426 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,03188814 0,04465825 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,03188814 0,04463227 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,03188814 0,04460632 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,03188814 0,0445804 ! immunoglobulin production GO:0002377 55 25 0,000 0,03188814 0,04455451 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,03188814 0,04452866 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,03188814 0,04450283 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,03188814 0,04447703 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,03188814 0,04445126 ! telomere organization GO:0032200 43 25 0,000 0,03188814 0,04442552 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,03188814 0,04439981 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,03188814 0,04437413 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,03314284 0,04609345 ! embryonic pattern specification GO:0009880 44 26 0,000 0,03314284 0,04606683 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,03314284 0,04604023 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,03314284 0,04601366 ! initiation of viral infection GO:0019059 57 26 0,000 0,03314284 0,04598713 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,03314284 0,04596062 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,03314284 0,04593415 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,03314284 0,0459077 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,03314284 0,04588129 ! molting cycle process GO:0022404 50 26 0,000 0,03314284 0,0458549 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,03314284 0,04582855 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,03314284 0,04580223 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,03314284 0,04577593 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,03314284 0,04574967 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,03314284 0,04572344 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,03314284 0,04569724 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,03314284 0,04567106 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,03314284 0,04564492 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,03314284 0,04561881 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,03314284 0,04559273 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,03314284 0,04556667 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,03314284 0,04554065 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,03314284 0,04551466 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,03314284 0,04548869 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,03314284 0,04546276 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,03314284 0,04543685 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,03314284 0,04541098 ! blastocyst development GO:0001824 49 26 0,000 0,03314284 0,04538513 ! leukocyte proliferation GO:0070661 52 26 0,000 0,03314284 0,04535932 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,03314284 0,04533353 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,03314284 0,04530777 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,03439595 0,04699413 ! neuron fate commitment GO:0048663 48 27 0,000 0,03439595 0,04696746 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,03439595 0,04694082 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,03439595 0,04691421 ! iron ion transport GO:0006826 59 27 0,000 0,03439595 0,04688763 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,03439595 0,04686108 ! protein amino acid acylation GO:0043543 55 27 0,000 0,03439595 0,04683456 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,03439595 0,04680807 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,03439595 0,04678161 ! fat cell differentiation GO:0045444 50 27 0,000 0,03439595 0,04675518 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,03439595 0,04672878 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,03439595 0,04670241 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,03439595 0,04667607 ! autophagy GO:0006914 41 27 0,000 0,03439595 0,04664976 ! male gonad development GO:0008584 44 27 0,000 0,03439595 0,04662347 ! response to toxin GO:0009636 47 27 0,000 0,03439595 0,04659722 ! primary neural tube formation GO:0014020 51 27 0,000 0,03439595 0,046571 ! base-excision repair GO:0006284 41 27 0,000 0,03439595 0,04654481 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,03439595 0,04651864 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,03439595 0,04649251 ! glutathione metabolic process GO:0006749 39 27 0,000 0,03439595 0,04646641 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,03439595 0,04644033 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,03439595 0,04641428 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,03439595 0,04638827 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,03439595 0,04636228 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,03564749 0,04802231 ! circadian rhythm GO:0007623 50 28 0,000 0,03564749 0,04799544 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,03564749 0,0479686 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,03564749 0,04794178 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,03564749 0,047915 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,03564749 0,04788825 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,03564749 0,04786152 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,03564749 0,04783483 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,03564749 0,04780817 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,03564749 0,04778153 ! synaptogenesis GO:0007416 42 28 0,000 0,03564749 0,04775493 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,03564749 0,04772835 ! lipid oxidation GO:0034440 43 28 0,000 0,03564749 0,04770181 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,03564749 0,04767529 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,03564749 0,04764881 ! translational initiation GO:0006413 65 29 0,000 0,03689744 0,04929219 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,03689744 0,04926483 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,03689744 0,04923751 ! regulation of pH GO:0006885 43 29 0,000 0,03689744 0,04921022 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,03689744 0,04918295 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,03689744 0,04915572 ! catechol metabolic process GO:0009712 54 29 0,000 0,03689744 0,04912852 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,03689744 0,04910134 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,03689744 0,0490742 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,03689744 0,04904709 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,03689744 0,04902001 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,03689744 0,04899295 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,03689744 0,04896593 ! cell fate determination GO:0001709 60 29 0,000 0,03689744 0,04893894 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,03689744 0,04891197 ! detection of light stimulus GO:0009583 38 29 0,000 0,03689744 0,04888504 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,03689744 0,04885813 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,03689744 0,04883126 ! tissue homeostasis GO:0001894 48 29 0,000 0,03689744 0,04880441 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,03689744 0,0487776 ! phenol metabolic process GO:0018958 55 30 0,000 0,03814581 0,05040023 ! zinc ion transport GO:0006829 45 30 0,000 0,03814581 0,05037256 ! membrane docking GO:0022406 61 30 0,000 0,03814581 0,05034493 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,03814581 0,05031733 ! regulation of innate immune response GO:0045088 51 30 0,000 0,03814581 0,05028976 ! acute-phase response GO:0006953 49 30 0,000 0,03814581 0,05026222 ! myofibril assembly GO:0030239 47 30 0,000 0,03814581 0,05023471 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,03814581 0,05020723 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,03814581 0,05017978 ! phospholipid transport GO:0015914 51 30 0,000 0,03814581 0,05015236 ! ensheathment of neurons GO:0007272 57 30 0,000 0,03814581 0,05012497 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,03814581 0,0500976 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,03814581 0,05007027 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,03814581 0,05004297 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,03814581 0,0500157 ! eye morphogenesis GO:0048592 60 30 0,000 0,03814581 0,04998846 ! regulation of B cell activation GO:0050864 50 30 0,000 0,03814581 0,04996125 ! response to heat GO:0009408 50 30 0,000 0,03814581 0,04993407 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,0393926 0,05153812 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,0393926 0,05151011 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,0393926 0,05148213 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,0393926 0,05145418 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,0393926 0,05142626 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,0393926 0,05139837 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,0393926 0,05137051 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,0393926 0,05134269 ! ovulation cycle process GO:0022602 49 31 0,000 0,0393926 0,05131489 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,0393926 0,05128712 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,0393926 0,05125938 ! peptide transport GO:0015833 55 31 0,000 0,0393926 0,05123168 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,0393926 0,051204 ! iron ion homeostasis GO:0055072 54 31 0,000 0,0393926 0,05117635 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,0393926 0,05114873 ! mesoderm formation GO:0001707 69 31 0,000 0,0393926 0,05112114 ! natural killer cell activation GO:0030101 45 31 0,000 0,0393926 0,05109358 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,0393926 0,05106606 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,0393926 0,05103856 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,0393926 0,05101109 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,0393926 0,05098365 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,0393926 0,05095624 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,04063782 0,05253874 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,04063782 0,05251053 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,04063782 0,05248234 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,04063782 0,05245418 ! cholesterol transport GO:0030301 56 32 0,000 0,04063782 0,05242606 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,04063782 0,05239796 ! spliceosome assembly GO:0000245 67 32 0,000 0,04063782 0,0523699 ! spindle organization GO:0007051 46 32 0,000 0,04063782 0,05234186 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,04063782 0,05231386 ! metanephros development GO:0001656 74 32 0,000 0,04063782 0,05228588 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,04063782 0,05225794 ! response to ionizing radiation GO:0010212 65 32 0,000 0,04063782 0,05223002 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,04063782 0,05220214 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,04063782 0,05217428 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,04063782 0,05214645 ! muscle cell development GO:0055001 49 32 0,000 0,04063782 0,05211866 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,04063782 0,05209089 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,04063782 0,05206315 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,04063782 0,05203544 ! ovulation cycle GO:0042698 51 32 0,000 0,04063782 0,05200777 ! peripheral nervous system development GO:0007422 64 32 0,000 0,04063782 0,05198012 ! BMP signaling pathway GO:0030509 64 32 0,000 0,04063782 0,0519525 ! hindbrain development GO:0030902 61 32 0,000 0,04063782 0,05192491 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,04063782 0,05189735 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,04063782 0,05186981 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,04063782 0,05184231 ! gene silencing GO:0016458 65 32 0,000 0,04063782 0,05181484 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,04188147 0,05337225 ! post-embryonic development GO:0009791 69 33 0,000 0,04188147 0,053344 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,04188147 0,05331577 ! protein targeting to membrane GO:0006612 68 33 0,000 0,04188147 0,05328758 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,04188147 0,05325942 ! formation of primary germ layer GO:0001704 72 33 0,000 0,04188147 0,05323128 ! cell fate specification GO:0001708 52 33 0,000 0,04188147 0,05320318 ! sterol transport GO:0015918 57 33 0,000 0,04188147 0,0531751 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,04188147 0,05314705 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,04188147 0,05311904 ! adult locomotory behavior GO:0008344 59 33 0,000 0,04188147 0,05309105 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,04188147 0,05306309 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,04188147 0,05303517 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,04312355 0,0545793 ! glial cell differentiation GO:0010001 63 34 0,000 0,04312355 0,0545506 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,04312355 0,05452194 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,04312355 0,0544933 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,04312355 0,0544647 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,04312355 0,05443612 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,04312355 0,05440758 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,04312355 0,05437906 ! mismatch repair GO:0006298 46 34 0,000 0,04312355 0,05435058 ! spermatid development GO:0007286 63 34 0,000 0,04312355 0,05432212 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,04312355 0,05429369 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,04312355 0,0542653 ! placenta development GO:0001890 53 34 0,000 0,04312355 0,05423693 ! regulation of muscle development GO:0048634 70 35 0,000 0,04436405 0,05576798 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,04436405 0,05573886 ! negative regulation of secretion GO:0051048 63 35 0,000 0,04436405 0,05570977 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,04436405 0,0556807 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,04436405 0,05565167 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,04436405 0,05562267 ! odontogenesis GO:0042476 66 35 0,000 0,04436405 0,0555937 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,04436405 0,05556476 ! female gonad development GO:0008585 58 35 0,000 0,04436405 0,05553585 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,04436405 0,05550697 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,04436405 0,05547812 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,04436405 0,0554493 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,04436405 0,05542051 ! cytokine production GO:0001816 59 35 0,000 0,04436405 0,05539175 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,04436405 0,05536302 ! neural tube formation GO:0001841 67 35 0,000 0,04436405 0,05533432 ! vesicle localization GO:0051648 64 35 0,000 0,04436405 0,05530565 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,04560299 0,05682072 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,04560299 0,0567913 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,04560299 0,05676192 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,04560299 0,05673258 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,04560299 0,05670326 ! positive regulation of cell development GO:0010720 80 36 0,000 0,04560299 0,05667397 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,04560299 0,05664471 ! regulation of proteolysis GO:0030162 72 36 0,000 0,04560299 0,05661548 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,04560299 0,05658628 ! aerobic respiration GO:0009060 55 36 0,000 0,04560299 0,05655711 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,04560299 0,05652798 ! embryonic organ development GO:0048568 57 36 0,000 0,04560299 0,05649887 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,04560299 0,05646979 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,04560299 0,05644074 ! RNA export from nucleus GO:0006405 56 37 0,000 0,04684037 0,05794238 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,04684037 0,0579126 ! meiosis I GO:0007127 65 37 0,000 0,04684037 0,05788286 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,04684037 0,05785314 ! sister chromatid segregation GO:0000819 58 37 0,000 0,04684037 0,05782346 ! actomyosin structure organization GO:0031032 62 37 0,000 0,04684037 0,05779381 ! organic anion transport GO:0015711 68 37 0,000 0,04684037 0,05776419 ! tissue remodeling GO:0048771 76 37 0,000 0,04684037 0,05773459 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,04684037 0,05770503 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,04684037 0,0576755 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,04684037 0,057646 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,04684037 0,05761653 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,04684037 0,05758709 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,04684037 0,05755767 ! glycogen metabolic process GO:0005977 61 37 0,000 0,04684037 0,05752829 ! pigment metabolic process GO:0042440 80 37 0,000 0,04684037 0,05749894 ! spermatid differentiation GO:0048515 66 37 0,000 0,04684037 0,05746962 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,04684037 0,05744033 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,04807618 0,05892577 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,04807618 0,05889577 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,04807618 0,0588658 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,04807618 0,05883585 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,04807618 0,05880594 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,04807618 0,05877606 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,04807618 0,05874621 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,04807618 0,05871639 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,04807618 0,0586866 ! lipid homeostasis GO:0055088 67 38 0,000 0,04807618 0,05865684 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,04807618 0,05862711 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,04807618 0,05859741 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,04807618 0,05856774 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,04807618 0,0585381 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,04807618 0,05850849 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,04807618 0,05847891 ! glucan metabolic process GO:0044042 62 38 0,000 0,04807618 0,05844936 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,04931043 0,05991964 ! mammary gland development GO:0030879 86 39 0,000 0,04931043 0,0598894 ! learning GO:0007612 77 39 0,000 0,04931043 0,05985918 ! ear morphogenesis GO:0042471 60 39 0,000 0,04931043 0,05982899 ! organic ether metabolic process GO:0018904 55 39 0,000 0,04931043 0,05979884 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,04931043 0,05976871 ! segmentation GO:0035282 67 39 0,000 0,04931043 0,05973862 ! ion transmembrane transport GO:0034220 66 39 0,000 0,04931043 0,05970855 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,04931043 0,05967852 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,04931043 0,05964852 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,04931043 0,05961854 ! RNA modification GO:0009451 57 39 0,000 0,04931043 0,0595886 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,04931043 0,05955868 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,05054312 0,06101694 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,05054312 0,06098634 ! feeding behavior GO:0007631 59 40 0,000 0,05054312 0,06095577 ! negative regulation of binding GO:0051100 72 40 0,000 0,05054312 0,06092523 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,05054312 0,06089472 ! mesenchymal cell development GO:0014031 87 40 0,000 0,05054312 0,06086424 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,05054312 0,06083379 ! maintenance of protein location GO:0045185 91 40 0,000 0,05054312 0,06080338 ! cytokinesis GO:0000910 72 40 0,000 0,05054312 0,06077299 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,05177426 0,06222221 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,05177426 0,06219114 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,05177426 0,06216011 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,05177426 0,06212911 ! gliogenesis GO:0042063 88 41 0,000 0,05177426 0,06209814 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,05177426 0,0620672 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,05177426 0,06203629 ! T cell differentiation GO:0030217 81 41 0,000 0,05177426 0,06200541 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,05177426 0,06197456 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,05177426 0,06194374 ! female gamete generation GO:0007292 61 41 0,000 0,05177426 0,06191295 ! polyol metabolic process GO:0019751 66 41 0,000 0,05177426 0,0618822 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,05177426 0,06185147 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,05300383 0,06328895 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,05300383 0,06325755 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,05300383 0,06322619 ! regulation of tube size GO:0035150 71 42 0,000 0,05300383 0,06319486 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,05300383 0,06316356 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,05300383 0,06313229 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,05300383 0,06310105 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,05300383 0,06306984 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,05300383 0,06303867 ! neuron migration GO:0001764 79 42 0,000 0,05300383 0,06300752 ! regulation of protein secretion GO:0050708 71 42 0,000 0,05300383 0,06297641 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,05300383 0,06294532 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,05423186 0,06437191 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,05423186 0,06434016 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,05423186 0,06430845 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,05423186 0,06427678 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,05423186 0,06424513 ! glucose transport GO:0015758 65 43 0,000 0,05423186 0,06421351 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,05423186 0,06418193 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,05423186 0,06415037 ! neural tube development GO:0021915 77 43 0,000 0,05423186 0,06411885 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,05423186 0,06408735 ! striated muscle contraction GO:0006941 77 43 0,000 0,05423186 0,06405589 ! phagocytosis GO:0006909 90 43 0,000 0,05423186 0,06402446 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,05423186 0,06399306 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,05545833 0,06540821 ! hexose transport GO:0008645 67 44 0,000 0,05545833 0,06537616 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,05545833 0,06534415 ! male sex differentiation GO:0046661 76 44 0,000 0,05545833 0,06531216 ! double-strand break repair GO:0006302 81 44 0,000 0,05545833 0,06528021 ! biopolymer methylation GO:0043414 84 44 0,000 0,05545833 0,06524829 ! B cell differentiation GO:0030183 107 44 0,000 0,05545833 0,0652164 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,05545833 0,06518454 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,05545833 0,06515271 ! developmental growth GO:0048589 82 44 0,000 0,05545833 0,06512091 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,05668326 0,06652679 ! glycolysis GO:0006096 65 45 0,000 0,05668326 0,06649435 ! leukocyte migration GO:0050900 68 45 0,000 0,05668326 0,06646195 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,05668326 0,06642957 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,05668326 0,06639723 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,05668326 0,06636492 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,05668326 0,06633264 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,05668326 0,0663004 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,05668326 0,06626818 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,05668326 0,066236 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,05668326 0,06620384 ! cell growth GO:0016049 84 45 0,000 0,05668326 0,06617172 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,05790663 0,0675671 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,05790663 0,06753435 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,05790663 0,06750163 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,05790663 0,06746894 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,05790663 0,06743628 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,05790663 0,06740366 ! response to insulin stimulus GO:0032868 95 46 0,000 0,05790663 0,06737106 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,05790663 0,0673385 ! positive regulation of defense response GO:0031349 76 47 0,000 0,05912846 0,06872613 ! response to calcium ion GO:0051592 81 47 0,000 0,05912846 0,06869294 ! endosome transport GO:0016197 108 47 0,000 0,05912846 0,06865979 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,05912846 0,06862667 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,05912846 0,06859358 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,05912846 0,06856052 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,05912846 0,06852749 ! JNK cascade GO:0007254 91 47 0,000 0,05912846 0,0684945 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,05912846 0,06846154 ! methylation GO:0032259 90 47 0,000 0,05912846 0,06842861 ! protein homooligomerization GO:0051260 76 47 0,000 0,05912846 0,06839571 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,06034875 0,06977371 ! mitochondrial transport GO:0006839 82 48 0,000 0,06034875 0,0697402 ! Notch signaling pathway GO:0007219 96 48 0,000 0,06034875 0,06970671 ! cellular component disassembly GO:0022411 86 48 0,000 0,06034875 0,06967327 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,06034875 0,06963985 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,06034875 0,06960647 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,06034875 0,06957311 ! activation of caspase activity GO:0006919 84 48 0,000 0,06034875 0,06953979 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,06034875 0,0695065 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,06034875 0,06947325 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,06034875 0,06944002 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,06034875 0,06940683 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,06156749 0,07077467 ! regulation of action potential GO:0001508 95 49 0,000 0,06156749 0,07074087 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,06156749 0,0707071 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,06156749 0,07067337 ! regulation of ion transport GO:0043269 77 49 0,000 0,06156749 0,07063967 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,06156749 0,070606 ! peptide metabolic process GO:0006518 76 49 0,000 0,06156749 0,07057236 ! response to temperature stimulus GO:0009266 76 49 0,000 0,06156749 0,07053875 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,06156749 0,07050518 ! endocrine system development GO:0035270 104 49 0,000 0,06156749 0,07047164 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,06156749 0,07043813 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,06156749 0,07040465 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,06156749 0,0703712 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,06156749 0,07033779 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,06278469 0,07169434 ! neuromuscular process GO:0050905 99 50 0,000 0,06278469 0,07166033 ! regulation of ossification GO:0030278 117 50 0,000 0,06278469 0,07162635 ! inner ear development GO:0048839 79 50 0,000 0,06278469 0,07159241 ! histone modification GO:0016570 91 50 0,000 0,06278469 0,07155849 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,06278469 0,07152461 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,06278469 0,07149076 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,06278469 0,07145694 ! positive regulation of binding GO:0051099 78 51 0,000 0,06400036 0,07280608 ! viral infectious cycle GO:0019058 99 51 0,000 0,06400036 0,07277168 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,06400036 0,0727373 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,06400036 0,07270296 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,06400036 0,07266865 ! excretion GO:0007588 83 51 0,000 0,06400036 0,07263437 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,06400036 0,07260012 ! chromatin remodeling GO:0006338 109 51 0,000 0,06400036 0,07256591 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,06400036 0,07253173 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,06400036 0,07249758 ! vesicle organization GO:0016050 107 51 0,000 0,06400036 0,07246347 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,06400036 0,07242938 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,06400036 0,07239533 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,06400036 0,07236131 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,06521449 0,07369942 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,06521449 0,07366482 ! membrane fusion GO:0006944 110 52 0,000 0,06521449 0,07363025 ! positive regulation of growth GO:0045927 90 52 0,000 0,06521449 0,07359571 ! covalent chromatin modification GO:0016569 101 52 0,000 0,06521449 0,07356121 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,06521449 0,07352674 ! amino acid activation GO:0043038 92 52 0,000 0,06521449 0,0734923 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,06521449 0,07345789 ! synapse organization GO:0050808 85 52 0,000 0,06521449 0,07342352 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,06642708 0,07475377 ! RNA catabolic process GO:0006401 93 53 0,000 0,06642708 0,07471882 ! regulation of translational initiation GO:0006446 82 53 0,000 0,06642708 0,07468391 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,06642708 0,07464902 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,06642708 0,07461417 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,06642708 0,07457936 ! cell maturation GO:0048469 100 53 0,000 0,06642708 0,07454457 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,06642708 0,07450982 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,06642708 0,0744751 ! response to UV GO:0009411 104 53 0,000 0,06642708 0,07444041 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,06763814 0,07576228 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,06763814 0,07572702 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,06763814 0,0756918 ! cell recognition GO:0008037 85 54 0,000 0,06763814 0,07565661 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,06763814 0,07562146 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,06763814 0,07558633 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,06763814 0,07555124 ! chloride transport GO:0006821 90 55 0,000 0,06884767 0,07686659 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,06884767 0,07683094 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,06884767 0,07679532 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,06884767 0,07675973 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,06884767 0,07672418 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,06884767 0,07668866 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,06884767 0,07665317 ! aging GO:0007568 103 55 0,000 0,06884767 0,07661772 ! gastrulation GO:0007369 112 55 0,000 0,06884767 0,07658229 ! heart morphogenesis GO:0003007 97 55 0,000 0,06884767 0,0765469 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,06884767 0,07651155 ! RNA elongation GO:0006354 79 55 0,000 0,06884767 0,07647622 ! nuclear export GO:0051168 97 55 0,000 0,06884767 0,07644093 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,06884767 0,07640567 ! regulation of actin filament length GO:0030832 105 56 0,000 0,07005567 0,07771044 ! sensory perception of smell GO:0007608 80 56 0,000 0,07005567 0,07767463 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,07005567 0,07763885 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,07005567 0,07760311 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,07005567 0,0775674 ! proton transport GO:0015992 94 56 0,000 0,07005567 0,07753172 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,07005567 0,07749607 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 0,000 0,07126215 0,07879445 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,07126215 0,07875826 ! muscle fiber development GO:0048747 112 57 0,000 0,07126215 0,0787221 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,07126215 0,07868597 ! lipid modification GO:0030258 97 57 0,000 0,07126215 0,07864988 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,07126215 0,07861382 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,07126215 0,07857779 ! hydrogen transport GO:0006818 97 58 0,000 0,0724671 0,07986983 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,0724671 0,07983326 ! regulation of endocytosis GO:0030100 91 58 0,000 0,0724671 0,07979672 ! adult behavior GO:0030534 99 58 0,000 0,0724671 0,07976022 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,0724671 0,07972375 ! positive regulation of secretion GO:0051047 95 59 0,000 0,07367052 0,08101064 ! regulation of cellular component size GO:0032535 109 59 0,000 0,07367052 0,08097363 ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,07367052 0,08093666 ! DNA catabolic process GO:0006308 86 59 0,000 0,07367052 0,08089972 ! establishment of organelle localization GO:0051656 109 59 0,000 0,07367052 0,08086281 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,07487243 0,08214458 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,07487243 0,08210714 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,07487243 0,08206973 ! regulation of heart contraction GO:0008016 110 60 0,000 0,07487243 0,08203236 ! camera-type eye development GO:0043010 116 60 0,000 0,07487243 0,08199502 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,07487243 0,08195772 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,07487243 0,08192045 ! kidney development GO:0001822 122 60 0,000 0,07487243 0,08188321 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,07607281 0,0831582 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,07607281 0,08312043 ! mesoderm development GO:0007498 119 61 0,000 0,07607281 0,0830827 ! tRNA processing GO:0008033 89 61 0,000 0,07607281 0,08304501 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,07607281 0,08300734 ! ear development GO:0043583 103 62 0,000 0,07727168 0,08427727 ! viral reproductive process GO:0022415 126 62 0,000 0,07727168 0,08423909 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,07727168 0,08420094 ! gonad development GO:0008406 98 62 0,000 0,07727168 0,08416282 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,07727168 0,08412474 ! regulation of mitosis GO:0007088 105 63 0,000 0,07846903 0,08538964 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,07846903 0,08535104 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,07846903 0,08531247 ! detection of external stimulus GO:0009581 91 63 0,000 0,07846903 0,08527394 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,07846903 0,08523544 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,07846903 0,08519697 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,07966487 0,08645633 ! cell redox homeostasis GO:0045454 102 64 0,000 0,07966487 0,08641735 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,07966487 0,0863784 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,07966487 0,0863395 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,07966487 0,08630062 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,07966487 0,08626178 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,0808592 0,08751562 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,0808592 0,08747627 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,0808592 0,08743696 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,0808592 0,08739768 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,0808592 0,08735843 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,08205201 0,08860733 ! actin filament organization GO:0007015 148 66 0,000 0,08205201 0,08856758 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,08205201 0,08852787 ! extracellular matrix organization GO:0030198 133 66 0,000 0,08205201 0,08848819 ! secondary metabolic process GO:0019748 116 66 0,000 0,08205201 0,08844854 ! developmental maturation GO:0021700 116 66 0,000 0,08205201 0,08840893 ! cell projection assembly GO:0030031 120 66 0,000 0,08205201 0,08836936 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,08324332 0,08961227 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,08324332 0,08957219 ! activation of MAPK activity GO:0000187 115 67 0,000 0,08324332 0,08953215 ! lung development GO:0030324 144 67 0,000 0,08324332 0,08949215 ! chromosome segregation GO:0007059 113 67 0,000 0,08324332 0,08945218 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,08324332 0,08941224 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,08324332 0,08937235 ! hexose catabolic process GO:0019320 104 67 0,000 0,08324332 0,08933248 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,08324332 0,08929266 ! adaptive immune response GO:0002250 119 67 0,000 0,08324332 0,08925286 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,08324332 0,08921311 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,08443312 0,09044795 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,08443312 0,09040769 ! viral reproduction GO:0016032 134 68 0,000 0,08443312 0,09036748 ! regulation of lipase activity GO:0060191 130 68 0,000 0,08443312 0,0903273 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,08443312 0,09028715 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,08443312 0,09024704 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,08562142 0,09147652 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,08562142 0,09143592 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,08562142 0,09139535 ! urogenital system development GO:0001655 137 69 0,000 0,08562142 0,09135482 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,08562142 0,09131433 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,08562142 0,09127387 ! antigen processing and presentation GO:0019882 104 69 0,000 0,08562142 0,09123345 ! appendage morphogenesis GO:0035107 135 70 0,000 0,08680821 0,09245708 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,08680821 0,09241617 ! amine catabolic process GO:0009310 117 71 0,000 0,0879935 0,09363661 ! reproductive structure development GO:0048608 113 71 0,000 0,0879935 0,09359521 ! appendage development GO:0048736 136 71 0,000 0,0879935 0,09355385 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,0879935 0,09351253 ! B cell activation GO:0042113 160 71 0,000 0,0879935 0,09347124 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,0879935 0,09342999 ! regulation of immune effector process GO:0002697 137 71 0,000 0,0879935 0,09338878 ! acute inflammatory response GO:0002526 113 72 0,000 0,0891773 0,09460343 ! regulation of caspase activity GO:0043281 122 72 0,000 0,0891773 0,09456173 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,0891773 0,09452008 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,0891773 0,09447846 ! carbohydrate transport GO:0008643 110 72 0,000 0,0891773 0,09443687 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,0891773 0,09439532 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,0891773 0,09435381 ! respiratory system development GO:0060541 153 72 0,000 0,0891773 0,09431234 ! regulation of blood pressure GO:0008217 125 73 0,000 0,09035959 0,09552073 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,09035959 0,09547878 ! axon guidance GO:0007411 139 73 0,000 0,09035959 0,09543686 ! fertilization GO:0009566 90 73 0,000 0,09035959 0,09539499 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,09154039 0,0965992 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,09154039 0,09655685 ! neurotransmitter transport GO:0006836 123 74 0,000 0,09154039 0,09651454 ! meiosis GO:0007126 121 74 0,000 0,09154039 0,09647227 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,09154039 0,09643003 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,09154039 0,09638783 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,09154039 0,09634566 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,09154039 0,09630353 ! eye development GO:0001654 143 74 0,000 0,09154039 0,09626144 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,0927197 0,09745898 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,0927197 0,09741642 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,0927197 0,0973739 ! meiotic cell cycle GO:0051321 122 75 0,000 0,0927197 0,09733141 ! rhythmic process GO:0048511 128 75 0,000 0,0927197 0,09728896 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,0927197 0,09724655 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,09389751 0,09843896 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,09389751 0,09839609 ! defense response to bacterium GO:0042742 89 76 0,000 0,09389751 0,09835325 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,09389751 0,09831045 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,09389751 0,09826769 ! regulation of catabolic process GO:0009894 161 76 0,000 0,09389751 0,09822497 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,09507384 0,09941228 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,09507384 0,0993691 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,09507384 0,09932595 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,09507384 0,09928284 ! blood coagulation GO:0007596 146 78 0,000 0,09624868 0,10046608 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,09624868 0,10042251 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,09624868 0,10037899 ! protein oligomerization GO:0051259 139 78 0,000 0,09624868 0,10033549 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,09742203 0,10151468 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,09742203 0,10147074 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,09742203 0,10142683 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,09742203 0,10138296 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,09742203 0,10133913 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,09742203 0,10129533 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,09742203 0,10125158 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,0985939 0,10242527 ! response to metal ion GO:0010038 140 80 0,000 0,0985939 0,10238106 ! muscle cell differentiation GO:0042692 159 80 0,000 0,0985939 0,10233689 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,0985939 0,10229276 ! protein import into nucleus GO:0006606 158 80 0,000 0,0985939 0,10224867 ! inorganic anion transport GO:0015698 138 80 0,000 0,0985939 0,10220462 ! T cell activation GO:0042110 168 81 0,000 0,09976428 0,10337332 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,09976428 0,10332882 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 0,000 0,09976428 0,10328436 ! digestion GO:0007586 112 81 0,000 0,09976428 0,10323994 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,09976428 0,10319555 ! nuclear import GO:0051170 161 81 0,000 0,09976428 0,10315121 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,09976428 0,1031069 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,10093318 0,10427018 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,10093318 0,10422543 ! response to drug GO:0042493 143 82 0,000 0,10093318 0,10418071 ! response to nutrient GO:0007584 125 82 0,000 0,10093318 0,10413604 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,10093318 0,1040914 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,10093318 0,1040468 ! response to oxygen levels GO:0070482 176 83 0,000 0,10210061 0,10520517 ! regulation of lyase activity GO:0051339 160 83 0,000 0,10210061 0,10516013 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,10326656 0,10631551 ! hemostasis GO:0007599 158 84 0,000 0,10326656 0,10627003 ! negative regulation of transport GO:0051051 153 84 0,000 0,10326656 0,1062246 ! regulation of ligase activity GO:0051340 142 84 0,000 0,10326656 0,1061792 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,10326656 0,10613385 ! response to unfolded protein GO:0006986 131 85 0,000 0,10443103 0,10728482 ! nucleosome assembly GO:0006334 122 85 0,000 0,10443103 0,10723903 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,10443103 0,10719328 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,10443103 0,10714757 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,10559403 0,10829464 ! response to inorganic substance GO:0010035 153 86 0,000 0,10559403 0,1082485 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,10559403 0,1082024 ! chromatin assembly GO:0031497 124 86 0,000 0,10559403 0,10815634 ! tube morphogenesis GO:0035239 176 86 0,000 0,10559403 0,10811031 ! mitochondrion organization GO:0007005 148 86 0,000 0,10559403 0,10806433 ! alcohol catabolic process GO:0046164 130 86 0,000 0,10559403 0,10801838 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,10675556 0,10916016 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,10675556 0,10911379 ! protein localization in nucleus GO:0034504 176 87 0,000 0,10675556 0,10906746 ! regulation of protein transport GO:0051223 154 87 0,000 0,10675556 0,10902117 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,10791561 0,11015909 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,10791561 0,11011237 ! regulation of DNA binding GO:0051101 155 88 0,000 0,10791561 0,11006569 ! gland development GO:0048732 206 88 0,000 0,10791561 0,11001905 ! regulation of neurological system process GO:0031644 148 88 0,000 0,10791561 0,10997246 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,10791561 0,1099259 ! cellular defense response GO:0006968 114 89 0,000 0,1090742 0,11105905 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,1090742 0,11101207 ! ossification GO:0001503 188 90 0,000 0,11023133 0,11214231 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,11023133 0,11209492 ! sex differentiation GO:0007548 145 90 0,000 0,11023133 0,11204756 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,11023133 0,11200024 ! bone development GO:0060348 189 91 0,000 0,11138699 0,11312667 ! sterol metabolic process GO:0016125 152 91 0,000 0,11138699 0,11307894 ! response to protein stimulus GO:0051789 149 91 0,000 0,11138699 0,11303125 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,11138699 0,1129836 ! regulation of defense response GO:0031347 149 92 0,000 0,11254118 0,11410623 ! nucleosome organization GO:0034728 138 92 0,000 0,11254118 0,11405817 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,11254118 0,11401014 ! vitamin metabolic process GO:0006766 139 92 0,000 0,11254118 0,11396216 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,11369392 0,11508101 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,11369392 0,11503262 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,11369392 0,11498427 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,11369392 0,11493595 ! regulation of membrane potential GO:0042391 164 93 0,000 0,11369392 0,11488768 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,11369392 0,11483945 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,1148452 0,11595365 ! female pregnancy GO:0007565 164 94 0,000 0,1148452 0,11590501 ! transcription initiation GO:0006352 153 94 0,000 0,1148452 0,11585641 ! regulation of T cell activation GO:0050863 158 94 0,000 0,1148452 0,11580785 ! interphase of mitotic cell cycle GO:0051329 209 95 0,000 0,11599502 0,11691831 ! forebrain development GO:0030900 188 95 0,000 0,11599502 0,11686935 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,11599502 0,11682043 ! leukocyte differentiation GO:0002521 202 96 0,000 0,11714338 0,1179276 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,11714338 0,11787828 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,11714338 0,117829 ! positive regulation of immune response GO:0050778 156 96 0,000 0,11714338 0,11777976 ! detection of stimulus GO:0051606 151 96 0,000 0,11714338 0,11773056 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,11829029 0,11883359 ! protein ubiquitination GO:0016567 217 97 0,000 0,11829029 0,11878399 ! hormone metabolic process GO:0042445 157 97 0,000 0,11829029 0,11873443 ! regulation of protein localization GO:0032880 176 97 0,000 0,11829029 0,11868492 ! response to virus GO:0009615 160 98 0,000 0,11943575 0,11978425 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,11943575 0,11973434 ! interphase GO:0051325 213 98 0,000 0,11943575 0,11968447 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,11943575 0,11963464 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,12057976 0,1207303 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,12057976 0,12068007 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,12057976 0,1206299 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 0,000 0,12172232 0,12172232