pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-pos-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/52-Desmedt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! autophagy GO:0006914 28 21 4,000 1,006E-08 2,314E-05 ! autophagic vacuole formation GO:0000045 8 5 2,000 4,437E-07 5,103E-04 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 2,000 4,437E-07 3,402E-04 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 2,000 4,437E-07 2,551E-04 ! estrogen receptor signaling pathway GO:0030520 30 18 3,000 4,511E-07 2,075E-04 ! macroautophagy GO:0016236 10 6 2,000 8,852E-07 3,393E-04 ! G1 phase of mitotic cell cycle GO:0000080 23 14 2,000 1,578E-05 5,185E-03 ! cellular response to starvation GO:0009267 21 14 2,000 1,578E-05 4,537E-03 ! G1 phase GO:0051318 27 16 2,000 2,416E-05 6,173E-03 ! cellular response to nutrient levels GO:0031669 27 18 2,000 3,502E-05 8,054E-03 ! response to starvation GO:0042594 30 19 2,000 4,148E-05 8,672E-03 ! steroid hormone receptor signaling pathway GO:0030518 96 58 3,000 5,615E-05 0,0107617 ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 5,664E-05 0,01002004 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 3,000 7,778E-05 0,01277744 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 8,553E-05 0,01311384 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 1,269E-04 0,01824521 ! microvillus organization GO:0032528 7 5 1,000 1,269E-04 0,01717196 GO:0030033|microvillus assembly, ! positive regulation of interleukin-4 production GO:0032753 8 5 1,000 1,269E-04 0,01621796 GO:0032754|positive regulation of interleukin-5 production, ! response to exogenous dsRNA GO:0043330 8 6 1,000 1,899E-04 0,022993 ! regulation of interleukin-5 production GO:0032674 9 6 1,000 1,899E-04 0,02184335 ! regulation of interleukin-13 production GO:0032656 11 6 1,000 1,899E-04 0,02080319 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 2,464E-04 0,02576444 ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 2,606E-04 0,02606293 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 2,653E-04 0,02542468 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 2,653E-04 0,02440769 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 2,653E-04 0,02346894 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 1,000 2,653E-04 0,02259972 ! negative regulation of interferon-gamma production GO:0032689 11 7 1,000 2,653E-04 0,02179258 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 1,000 2,653E-04 0,02104112 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 1,000 2,653E-04 0,02033974 ! regulation of protein homodimerization activity GO:0043496 15 7 1,000 2,653E-04 0,01968362 ! B cell receptor signaling pathway GO:0050853 11 7 1,000 2,653E-04 0,01906851 ! interphase GO:0051325 159 88 3,000 2,847E-04 0,01984021 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 3,529E-04 0,02387351 ! middle ear morphogenesis GO:0042474 9 8 1,000 3,529E-04 0,02319141 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 1,000 3,529E-04 0,0225472 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 3,529E-04 0,02193782 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 3,529E-04 0,02136051 ! regulation of interleukin-4 production GO:0032673 16 8 1,000 3,529E-04 0,0208128 ! regulation of telomere maintenance GO:0032204 10 8 1,000 3,529E-04 0,02029248 ! negative regulation of DNA replication initiation GO:0032297 9 8 1,000 3,529E-04 0,01979755 GO:0000076|DNA replication checkpoint, ! retinoic acid receptor signaling pathway GO:0048384 15 9 1,000 4,527E-04 0,02479022 ! positive regulation of phagocytosis GO:0050766 11 9 1,000 4,527E-04 0,0242137 ! regulation of DNA replication initiation GO:0030174 13 9 1,000 4,527E-04 0,02366339 ! oocyte differentiation GO:0009994 12 9 1,000 4,527E-04 0,02313754 GO:0048599|oocyte development, ! pyrimidine base metabolic process GO:0006206 14 9 1,000 4,527E-04 0,02263455 ! embryonic placenta development GO:0001892 12 9 1,000 4,527E-04 0,02215296 ! activation of caspase activity GO:0006919 65 43 2,000 4,966E-04 0,02379746 ! vesicle organization GO:0016050 79 43 2,000 4,966E-04 0,02331179 ! response to insulin stimulus GO:0032868 63 43 2,000 4,966E-04 0,02284556 ! response to dsRNA GO:0043331 18 10 1,000 5,645E-04 0,02546008 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 1,000 5,645E-04 0,02497046 ! T cell receptor signaling pathway GO:0050852 18 10 1,000 5,645E-04 0,02449932 ! cell maturation GO:0048469 60 45 2,000 5,681E-04 0,02419818 ! positive regulation of caspase activity GO:0043280 72 48 2,000 6,872E-04 0,02873671 GO:0010952|positive regulation of peptidase activity, ! detection of mechanical stimulus GO:0050982 15 11 1,000 6,884E-04 0,02827369 ! regulation of phagocytosis GO:0050764 14 11 1,000 6,884E-04 0,02777766 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 1,000 6,884E-04 0,02729873 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 8,211E-04 0,03200726 ! regulation of protein catabolic process GO:0042176 77 51 2,000 8,211E-04 0,03147381 ! cartilage condensation GO:0001502 18 12 1,000 8,242E-04 0,03107511 ! skeletal system morphogenesis GO:0048705 78 53 2,000 9,189E-04 0,03408764 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 1,000 9,718E-04 0,03547673 ! pituitary gland development GO:0021983 23 14 1,000 1,131E-03 0,04064828 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 1,131E-03 0,04002292 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 1,000 1,131E-03 0,03941651 ! regulation of T-helper 2 type immune response GO:0002828 21 14 1,000 1,131E-03 0,03882821 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 1,131E-03 0,0382572 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 1,136E-03 0,03786758 ! developmental maturation GO:0021700 75 57 2,000 1,136E-03 0,03732661 ! regulation of survival gene product expression GO:0045884 20 15 1,000 1,302E-03 0,04217967 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 1,302E-03 0,04159384 ! regulation of T-helper cell differentiation GO:0045622 23 15 1,000 1,302E-03 0,04102406 ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 1,302E-03 0,04046968 ! regulation of heart contraction GO:0008016 91 60 2,000 1,318E-03 0,04043212 ! cellular response to unfolded protein GO:0034620 19 16 1,000 1,485E-03 0,0449295 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of protein binding GO:0043393 27 16 1,000 1,485E-03 0,044346 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 1,000 1,485E-03 0,04377747 ! diencephalon development GO:0021536 25 16 1,000 1,485E-03 0,04322332 ! oogenesis GO:0048477 23 16 1,000 1,485E-03 0,04268303 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 1,000 1,485E-03 0,04215608 ! regulation of caspase activity GO:0043281 97 65 2,000 1,662E-03 0,04660386 ! zinc ion transport GO:0006829 20 17 1,000 1,679E-03 0,04651754 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 1,679E-03 0,04596376 ! nucleobase metabolic process GO:0009112 31 17 1,000 1,679E-03 0,04542301 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 1,813E-03 0,04848581 ! positive regulation of angiogenesis GO:0045766 35 18 1,000 1,884E-03 0,04981044 ! protein amino acid ADP-ribosylation GO:0006471 27 18 1,000 1,884E-03 0,04924441 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 1,884E-03 0,04869111 ! response to retinoic acid GO:0032526 25 18 1,000 1,884E-03 0,04815009 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 1,000 1,884E-03 0,04762097 ! regulation of catabolic process GO:0009894 106 70 2,000 2,056E-03 0,0513948 ! response to alkaloid GO:0043279 32 19 1,000 2,101E-03 0,05195817 ! response to vitamin A GO:0033189 26 19 1,000 2,101E-03 0,05140543 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 2,101E-03 0,05086432 ! apoptotic nuclear changes GO:0030262 24 19 1,000 2,101E-03 0,05033448 ! response to lipopolysaccharide GO:0032496 26 19 1,000 2,101E-03 0,04981557 ! protein stabilization GO:0050821 26 19 1,000 2,101E-03 0,04930725 ! regulation of peptidase activity GO:0052547 106 72 2,000 2,228E-03 0,05177086 ! response to vitamin GO:0033273 29 20 1,000 2,329E-03 0,05356574 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 2,41E-03 0,05487553 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 2,568E-03 0,05790894 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 2,568E-03 0,05734672 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 2,568E-03 0,05679531 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 2,568E-03 0,0562544 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 1,000 2,568E-03 0,0557237 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 1,000 2,568E-03 0,05520291 ! negative regulation of cytokine production GO:0001818 31 21 1,000 2,568E-03 0,05469178 ! response to unfolded protein GO:0006986 99 76 2,000 2,6E-03 0,05486243 ! gland development GO:0048732 148 77 2,000 2,699E-03 0,05642337 ! protein ubiquitination GO:0016567 125 77 2,000 2,699E-03 0,05591505 ! positive regulation of protein modification process GO:0031401 107 78 2,000 2,799E-03 0,05748551 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 1,000 2,818E-03 0,05736583 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of tumor necrosis factor production GO:0032680 28 22 1,000 2,818E-03 0,05686262 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 3,08E-03 0,06159365 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 3,08E-03 0,06106267 ! negative regulation of DNA replication GO:0008156 35 23 1,000 3,08E-03 0,06054077 ! negative regulation of catabolic process GO:0009895 34 23 1,000 3,08E-03 0,06002771 ! response to molecule of bacterial origin GO:0002237 30 23 1,000 3,08E-03 0,05952328 ! cell fate determination GO:0001709 45 23 1,000 3,08E-03 0,05902725 ! response to protein stimulus GO:0051789 111 81 2,000 3,115E-03 0,05922011 ! regulation of interferon-gamma production GO:0032649 30 24 1,000 3,352E-03 0,06319116 ! fat cell differentiation GO:0045444 37 24 1,000 3,352E-03 0,06267741 ! regulation of alpha-beta T cell activation GO:0046634 35 24 1,000 3,352E-03 0,06217195 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 3,57E-03 0,06568822 ! transcription initiation GO:0006352 118 85 2,000 3,57E-03 0,06516689 ! iron ion homeostasis GO:0055072 39 25 1,000 3,635E-03 0,06582921 ! response to estradiol stimulus GO:0032355 34 25 1,000 3,635E-03 0,06531492 ! regulation of chromosome organization GO:0033044 35 25 1,000 3,635E-03 0,0648086 ! protein modification by small protein conjugation GO:0032446 140 90 2,000 4,192E-03 0,07417499 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 4,233E-03 0,07432343 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of endocytosis GO:0045807 33 28 1,000 4,548E-03 0,07925061 ! immune response-activating signal transduction GO:0002757 38 28 1,000 4,548E-03 0,07865474 GO:0002764|immune response-regulating signal transduction, ! positive regulation of T cell differentiation GO:0045582 39 28 1,000 4,548E-03 0,07806776 ! placenta development GO:0001890 37 28 1,000 4,548E-03 0,07748948 ! regulation of binding GO:0051098 151 95 2,000 4,877E-03 0,08248015 ! carboxylic acid transport GO:0046942 147 95 2,000 4,877E-03 0,0818781 GO:0015849|organic acid transport, ! protein modification by small protein conjugation or removal GO:0070647 148 96 2,000 5,022E-03 0,08369348 ! organic anion transport GO:0015711 51 30 1,000 5,21E-03 0,0862084 ! response to heat GO:0009408 41 30 1,000 5,21E-03 0,08559262 ! mammary gland development GO:0030879 57 31 1,000 5,556E-03 0,09063679 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 5,556E-03 0,0899985 ! response to mechanical stimulus GO:0009612 43 31 1,000 5,556E-03 0,08936914 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 5,913E-03 0,09444646 ! regulation of protein stability GO:0031647 48 32 1,000 5,913E-03 0,09379511 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 1,000 5,913E-03 0,09315268 ! ear morphogenesis GO:0042471 42 33 1,000 6,28E-03 0,09826055 ! nucleus organization GO:0006997 49 33 1,000 6,28E-03 0,09759663 ! negative regulation of DNA binding GO:0043392 54 33 1,000 6,28E-03 0,09694162 ! DNA integrity checkpoint GO:0031570 57 34 1,000 6,657E-03 0,10207762 ! female gamete generation GO:0007292 43 34 1,000 6,657E-03 0,10140161 ! negative regulation of binding GO:0051100 58 36 1,000 7,442E-03 0,11260285 ! monocarboxylic acid transport GO:0015718 62 38 1,000 8,266E-03 0,12425412 ! pigmentation GO:0043473 74 38 1,000 8,266E-03 0,12344728 ! response to calcium ion GO:0051592 58 40 1,000 9,129E-03 0,13545822 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 9,129E-03 0,13458989 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 9,129E-03 0,13373263 ! protein amino acid lipidation GO:0006497 62 41 1,000 9,575E-03 0,13937901 ! regulation of T cell differentiation GO:0045580 59 41 1,000 9,575E-03 0,13850241 ! mitochondrial transport GO:0006839 60 42 1,000 0,01003031 0,1441857 ! cellular component disassembly GO:0022411 64 42 1,000 0,01003031 0,14329013 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 0,01049537 0,14900829 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,01049537 0,14809413 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 1,000 0,01049537 0,14719111 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,01096983 0,15291279 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,01145363 0,15869488 ! regulation of translational initiation GO:0006446 64 45 1,000 0,01145363 0,15774461 ! lipoprotein biosynthetic process GO:0042158 67 45 1,000 0,01145363 0,15680566 ! regulation of adaptive immune response GO:0002819 72 46 1,000 0,0119467 0,16258816 ! response to UV GO:0009411 75 46 1,000 0,0119467 0,16163176 ! response to estrogen stimulus GO:0043627 74 47 1,000 0,01244895 0,16744206 ! endocrine system development GO:0035270 83 47 1,000 0,01244895 0,16646856 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,01244895 0,16550631 ! response to temperature stimulus GO:0009266 62 48 1,000 0,01296033 0,17131477 ! regulation of DNA replication GO:0006275 75 48 1,000 0,01296033 0,17033583 ! regulation of endocytosis GO:0030100 63 48 1,000 0,01296033 0,16936801 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,01296033 0,16841113 ! positive regulation of cytokine production GO:0001819 73 48 1,000 0,01296033 0,167465 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,01348077 0,17321658 ! germ cell development GO:0007281 68 49 1,000 0,01348077 0,17225427 ! cartilage development GO:0051216 70 49 1,000 0,01348077 0,17130259 ! ear development GO:0043583 72 50 1,000 0,01401019 0,17705181 ! membrane fusion GO:0006944 80 50 1,000 0,01401019 0,17608432 ! positive regulation of cell migration GO:0030335 92 51 1,000 0,01454852 0,18185648 ! transition metal ion transport GO:0000041 74 52 1,000 0,0150957 0,18767622 ! cell projection assembly GO:0030031 76 53 1,000 0,01565165 0,1935419 ! DNA catabolic process GO:0006308 67 54 1,000 0,01621631 0,19945195 ! detection of external stimulus GO:0009581 66 54 1,000 0,01621631 0,19839103 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 0,01737149 0,21139905 ! positive regulation of cell motion GO:0051272 99 56 1,000 0,01737149 0,21028642 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01789117 0,21544336 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01789117 0,21432126 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01789117 0,21321078 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01789117 0,21211176 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01789117 0,21102401 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01789117 0,20994735 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01789117 0,20888163 ! sleep GO:0030431 11 5 0,000 0,01789117 0,20782667 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01789117 0,20678232 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01789117 0,20574841 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01789117 0,20472478 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01789117 0,20371129 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01789117 0,20270779 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01789117 0,20171412 ! tongue development GO:0043586 6 5 0,000 0,01789117 0,20073015 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01789117 0,19975573 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01789117 0,19879073 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01789117 0,197835 ! cobalt ion transport GO:0006824 9 5 0,000 0,01789117 0,19688843 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01789117 0,19595086 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01789117 0,19502218 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01789117 0,19410227 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01789117 0,19319099 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01789117 0,19228823 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01789117 0,19139387 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01789117 0,19050778 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01789117 0,18962987 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01789117 0,18876 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01789117 0,18789809 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01789117 0,187044 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01789117 0,18619765 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,01789117 0,18535892 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01789117 0,18452772 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01789117 0,18370393 ! malate metabolic process GO:0006108 7 5 0,000 0,01789117 0,18288747 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01789117 0,18207823 ! behavioral response to pain GO:0048266 7 5 0,000 0,01789117 0,18127613 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01789117 0,18048106 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01789117 0,17969293 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01789117 0,17891166 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01789117 0,17813715 ! mating behavior GO:0007617 6 5 0,000 0,01789117 0,17736931 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01789117 0,17660807 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01789117 0,17585334 ! rhythmic behavior GO:0007622 12 5 0,000 0,01789117 0,17510503 ! copulation GO:0007620 7 5 0,000 0,01789117 0,17436306 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01789117 0,17362735 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01789117 0,17289782 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01789117 0,1721744 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01789117 0,171457 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01789117 0,17074556 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01789117 0,17004 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01789117 0,16934025 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01789117 0,16864623 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01789117 0,16795788 ! response to protozoan GO:0001562 9 5 0,000 0,01789117 0,16727513 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,01789117 0,1665979 ! lymph vessel development GO:0001945 7 5 0,000 0,01789117 0,16592613 ! endochondral ossification GO:0001958 12 5 0,000 0,01789117 0,16525976 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01789117 0,16459872 ! parathyroid gland development GO:0060017 8 5 0,000 0,01789117 0,16394295 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01789117 0,16329239 ! anagen GO:0042640 6 5 0,000 0,01789117 0,16264696 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01789117 0,16200662 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01789117 0,1613713 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01789117 0,16074094 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01789117 0,16011549 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01789117 0,15949489 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01789117 0,15887908 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01789117 0,158268 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01789117 0,15766161 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01789117 0,15705985 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01789117 0,15646267 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01789117 0,15587 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01789117 0,15528182 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01789117 0,15469805 ! ovulation GO:0030728 6 5 0,000 0,01789117 0,15411866 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01789117 0,15354359 GO:0033135|regulation of peptidyl-serine phosphorylation, ! valine metabolic process GO:0006573 8 5 0,000 0,01789117 0,15297279 ! response to pH GO:0009268 9 5 0,000 0,01789117 0,15240623 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01789117 0,15184384 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01789117 0,15128559 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01789117 0,15073143 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01789117 0,15018132 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01789117 0,1496352 ! polyol catabolic process GO:0046174 7 5 0,000 0,01789117 0,14909305 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01789117 0,14855481 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01789117 0,14802044 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01789117 0,1474899 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01789117 0,14696315 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01789117 0,14644015 ! urea metabolic process GO:0019627 6 5 0,000 0,01789117 0,14592085 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01789117 0,14540523 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01789117 0,14489324 ! neutrophil activation GO:0042119 5 5 0,000 0,01789117 0,14438485 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01789117 0,14388 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01789117 0,14337868 ! response to food GO:0032094 5 5 0,000 0,01789117 0,14288084 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01789117 0,14238644 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01789117 0,14189545 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01789117 0,14140784 ! forebrain neuron development GO:0021884 7 5 0,000 0,01789117 0,14092357 ! melanosome organization GO:0032438 7 5 0,000 0,01789117 0,1404426 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01789117 0,1399649 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01789117 0,13949044 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01789117 0,13901919 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01789117 0,13855111 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01789117 0,13808618 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01789117 0,13762435 ! nucleoside transport GO:0015858 6 5 0,000 0,01789117 0,1371656 ! nucleoside salvage GO:0043174 7 5 0,000 0,01789117 0,1367099 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01789117 0,13625722 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01789117 0,13580753 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01789117 0,13536079 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01789117 0,13491699 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01789117 0,13447608 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01789117 0,13403805 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01789117 0,13360286 ! depyrimidination GO:0045008 8 5 0,000 0,01789117 0,13317049 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01789117 0,13274091 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01789117 0,13231409 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01789117 0,13189 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01789117 0,13146863 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01789117 0,13104994 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01789117 0,13063391 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01789117 0,13022051 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01789117 0,12980972 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01789117 0,12940151 ! monocyte differentiation GO:0030224 8 5 0,000 0,01789117 0,12899587 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01789117 0,12859275 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01789117 0,12819215 ! centrosome duplication GO:0051298 5 5 0,000 0,01789117 0,12779404 ! response to UV-C GO:0010225 6 5 0,000 0,01789117 0,12739839 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01789117 0,12700519 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01789117 0,1266144 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01789117 0,12622602 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01789117 0,12584 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01789117 0,12545634 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01789117 0,12507502 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01789117 0,124696 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01789117 0,12431928 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01789117 0,12394482 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01789117 0,12357262 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01789117 0,12320264 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01789117 0,12283487 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01789117 0,12246929 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01789117 0,12210588 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01789117 0,12174462 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01789117 0,12138549 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01789117 0,12102847 ! neural tube patterning GO:0021532 6 5 0,000 0,01789117 0,12067355 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01789117 0,1203207 ! histone demethylation GO:0016577 9 5 0,000 0,01789117 0,11996992 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01789117 0,11962117 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01789117 0,11927444 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01789117 0,11892971 ! enteric nervous system development GO:0048484 8 5 0,000 0,01789117 0,11858698 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01789117 0,11824621 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01789117 0,1179074 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01789117 0,11757052 ! transcription termination GO:0006353 8 5 0,000 0,01789117 0,11723556 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01789117 0,1169025 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01789117 0,11657133 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01789117 0,11624204 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,01789117 0,11591459 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01789117 0,11558899 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01789117 0,11526521 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01789117 0,11494324 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01789117 0,11462307 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01789117 0,11430467 ! apical protein localization GO:0045176 6 5 0,000 0,01789117 0,11398804 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01789117 0,11367315 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01789117 0,11336 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01789117 0,11304857 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01789117 0,11273885 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01789117 0,11243082 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01789117 0,11212447 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01789117 0,11181979 ! glial cell migration GO:0008347 10 5 0,000 0,01789117 0,11151675 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01789117 0,11121535 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01789117 0,11091558 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01789117 0,11061742 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01789117 0,11032086 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01789117 0,11002589 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01789117 0,10973248 ! neural plate development GO:0001840 6 5 0,000 0,01789117 0,10944064 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,01789117 0,10915035 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01789117 0,10886159 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01789117 0,10857436 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01789117 0,10828863 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01789117 0,10800441 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01789117 0,10772168 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01789117 0,10744042 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01789117 0,10716063 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01789117 0,10688229 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01789117 0,10660539 ! spindle assembly GO:0051225 5 5 0,000 0,01789117 0,10632993 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01789117 0,10605588 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01789117 0,10578324 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01789117 0,105512 ! organ regeneration GO:0031100 7 5 0,000 0,01789117 0,10524215 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01789117 0,10497368 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01789117 0,10470657 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,01789117 0,10444081 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01789117 0,10417641 GO:0055081|anion homeostasis, ! actin filament organization GO:0007015 95 59 1,000 0,01916788 0,11132859 ! regulation of vesicle-mediated transport GO:0060627 79 60 1,000 0,01978338 0,11461402 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,01978338 0,11432604 ! meiosis GO:0007126 96 61 1,000 0,02040711 0,117635 GO:0051327|M phase of meiotic cell cycle, ! lipoprotein metabolic process GO:0042157 89 61 1,000 0,02040711 0,11734091 ! meiotic cell cycle GO:0051321 97 62 1,000 0,02103903 0,12067273 ! tRNA transcription GO:0009304 11 6 0,000 0,02143141 0,12261752 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02143141 0,12231326 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,02143141 0,1220105 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02143141 0,12170924 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02143141 0,12140947 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,02143141 0,12111116 ! regulation of helicase activity GO:0051095 11 6 0,000 0,02143141 0,12081432 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02143141 0,12051893 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02143141 0,12022498 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02143141 0,11993247 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02143141 0,11964137 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02143141 0,11935168 ! prostate gland development GO:0030850 9 6 0,000 0,02143141 0,11906339 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02143141 0,11877649 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02143141 0,11849097 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02143141 0,11820682 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,02143141 0,11792403 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02143141 0,11764259 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02143141 0,11736249 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02143141 0,11708371 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02143141 0,11680627 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,02143141 0,11653013 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,02143141 0,11625529 ! neuron adhesion GO:0007158 9 6 0,000 0,02143141 0,11598175 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,02143141 0,11570949 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02143141 0,11543851 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02143141 0,11516879 ! signal peptide processing GO:0006465 8 6 0,000 0,02143141 0,11490034 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02143141 0,11463313 ! mRNA stabilization GO:0048255 15 6 0,000 0,02143141 0,11436716 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,02143141 0,11410242 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02143141 0,1138389 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02143141 0,1135766 ! opsonization GO:0008228 8 6 0,000 0,02143141 0,1133155 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02143141 0,11305561 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02143141 0,1127969 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02143141 0,11253937 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02143141 0,11228302 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02143141 0,11202783 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02143141 0,1117738 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02143141 0,11152091 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02143141 0,11126917 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02143141 0,11101857 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02143141 0,11076909 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02143141 0,11052073 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02143141 0,11027348 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02143141 0,11002733 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02143141 0,10978228 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02143141 0,10953832 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02143141 0,10929544 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02143141 0,10905364 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02143141 0,1088129 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,02143141 0,10857322 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02143141 0,1083346 ! thymic T cell selection GO:0045061 12 6 0,000 0,02143141 0,10809703 ! protein lipoylation GO:0009249 10 6 0,000 0,02143141 0,10786049 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02143141 0,10762499 ! pigment granule organization GO:0048753 11 6 0,000 0,02143141 0,10739051 ! drug transport GO:0015893 6 6 0,000 0,02143141 0,10715705 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02143141 0,10692461 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,02143141 0,10669317 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02143141 0,10646273 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02143141 0,10623328 ! histidine metabolic process GO:0006547 6 6 0,000 0,02143141 0,10600483 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02143141 0,10577735 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02143141 0,10555084 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,02143141 0,10532531 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,02143141 0,10510073 ! adenohypophysis development GO:0021984 10 6 0,000 0,02143141 0,10487711 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02143141 0,10465445 ! hyperosmotic response GO:0006972 8 6 0,000 0,02143141 0,10443272 ! microtubule nucleation GO:0007020 10 6 0,000 0,02143141 0,10421193 ! ER overload response GO:0006983 7 6 0,000 0,02143141 0,10399208 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02143141 0,10377314 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02143141 0,10355513 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02143141 0,10333804 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02143141 0,10312185 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02143141 0,10290656 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02143141 0,10269217 ! response to dietary excess GO:0002021 7 6 0,000 0,02143141 0,10247868 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02143141 0,10226607 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,02143141 0,10205434 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02143141 0,10184348 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02143141 0,10163349 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02143141 0,10142437 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,02143141 0,10121611 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02143141 0,1010087 ! neuron apoptosis GO:0051402 8 6 0,000 0,02143141 0,10080213 ! organic alcohol transport GO:0015850 9 6 0,000 0,02143141 0,10059642 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,02143141 0,10039154 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02143141 0,10018749 ! male sex determination GO:0030238 9 6 0,000 0,02143141 0,09998427 ! carnitine transport GO:0015879 8 6 0,000 0,02143141 0,09978187 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02143141 0,09958029 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02143141 0,09937952 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,02143141 0,09917957 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02143141 0,09898041 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02143141 0,09878205 ! parturition GO:0007567 12 6 0,000 0,02143141 0,09858449 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02143141 0,09838771 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02143141 0,09819172 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02143141 0,09799651 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,02143141 0,09780207 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,02143141 0,0976084 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02143141 0,0974155 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,02143141 0,09722336 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02143141 0,09703198 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02143141 0,09684134 ! macrophage differentiation GO:0030225 10 6 0,000 0,02143141 0,09665146 ! astrocyte development GO:0014002 14 6 0,000 0,02143141 0,09646232 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02143141 0,09627391 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02143141 0,09608625 ! interaction with symbiont GO:0051702 8 6 0,000 0,02143141 0,09589931 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02143141 0,09571309 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02143141 0,0955276 ! eating behavior GO:0042755 6 6 0,000 0,02143141 0,09534283 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02143141 0,09515877 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02143141 0,09497542 ! response to copper ion GO:0046688 9 6 0,000 0,02143141 0,09479278 ! DNA topological change GO:0006265 8 6 0,000 0,02143141 0,09461083 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,02143141 0,09442959 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02143141 0,09424903 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02143141 0,09406917 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02143141 0,09388999 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,02143141 0,09371149 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02143141 0,09353367 ! gas homeostasis GO:0033483 11 6 0,000 0,02143141 0,09335652 ! hair follicle maturation GO:0048820 7 6 0,000 0,02143141 0,09318005 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02143141 0,09300423 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02143141 0,09282908 ! Schwann cell development GO:0014044 14 6 0,000 0,02143141 0,09265459 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02143141 0,09248076 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02143141 0,09230757 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02143141 0,09213504 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02143141 0,09196314 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02143141 0,09179189 ! histone ubiquitination GO:0016574 7 6 0,000 0,02143141 0,09162127 ! regulation of meiosis GO:0040020 10 6 0,000 0,02143141 0,09145129 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,02143141 0,09128193 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02143141 0,0911132 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02143141 0,0909451 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02143141 0,09077761 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02143141 0,09061074 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02143141 0,09044448 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02143141 0,09027883 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02143141 0,09011379 ! receptor internalization GO:0031623 9 6 0,000 0,02143141 0,08994935 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02143141 0,08978551 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02143141 0,08962226 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02143141 0,08945961 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02143141 0,08929754 ! protein deubiquitination GO:0016579 8 6 0,000 0,02143141 0,08913606 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02143141 0,08897517 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,02143141 0,08881485 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02143141 0,08865511 ! axonal fasciculation GO:0007413 9 6 0,000 0,02143141 0,08849595 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02143141 0,08833735 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02143141 0,08817933 ! midbrain development GO:0030901 6 6 0,000 0,02143141 0,08802186 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02143141 0,08786496 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02143141 0,08770862 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02143141 0,08755283 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02143141 0,0873976 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02143141 0,08724291 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02143141 0,08708877 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02143141 0,08693517 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02143141 0,08678212 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02143141 0,0866296 ! adult feeding behavior GO:0008343 6 6 0,000 0,02143141 0,08647762 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02143141 0,08632617 ! blastocyst growth GO:0001832 15 6 0,000 0,02143141 0,08617525 ! pigment granule transport GO:0051904 12 6 0,000 0,02143141 0,08602486 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02143141 0,08587499 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02143141 0,08572564 ! catecholamine transport GO:0051937 7 6 0,000 0,02143141 0,08557681 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02143141 0,0854285 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02143141 0,0852807 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02143141 0,08513341 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02143141 0,08498663 ! protein prenylation GO:0018342 10 6 0,000 0,02143141 0,08484035 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02143141 0,08469458 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,02143141 0,0845493 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,02143141 0,08440453 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,02143141 0,08426025 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02143141 0,08411646 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,02167905 0,08494348 GO:0090046|regulation of transcription regulator activity, ! cell cycle checkpoint GO:0000075 108 64 1,000 0,02232712 0,08733398 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 0,02232712 0,08718571 ! positive regulation of T cell activation GO:0050870 94 65 1,000 0,02298317 0,08959542 ! activation of immune response GO:0002253 83 65 1,000 0,02298317 0,08944382 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,0249591 0,09696946 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,0249591 0,09680593 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,0249591 0,09664296 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,0249591 0,09648054 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,0249591 0,09631866 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0249591 0,09615732 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,0249591 0,09599652 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0249591 0,09583626 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,0249591 0,09567653 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,0249591 0,09551734 ! reproductive behavior GO:0019098 12 7 0,000 0,0249591 0,09535867 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,0249591 0,09520053 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,0249591 0,09504291 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,0249591 0,09488582 ! oligopeptide transport GO:0006857 11 7 0,000 0,0249591 0,09472924 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,0249591 0,09457318 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,0249591 0,09441763 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,0249591 0,09426259 ! RNA methylation GO:0001510 11 7 0,000 0,0249591 0,09410806 ! pericardium development GO:0060039 8 7 0,000 0,0249591 0,09395404 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,0249591 0,09380052 ! fibril organization GO:0043206 13 7 0,000 0,0249591 0,0936475 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,0249591 0,09349498 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0249591 0,09334296 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,0249591 0,09319143 ! lipoprotein transport GO:0042953 9 7 0,000 0,0249591 0,09304039 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,0249591 0,09288984 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0249591 0,09273977 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0249591 0,09259019 ! estrogen metabolic process GO:0008210 14 7 0,000 0,0249591 0,09244109 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,0249591 0,09229247 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,0249591 0,09214433 ! chemosensory behavior GO:0007635 9 7 0,000 0,0249591 0,09199667 ! microtubule bundle formation GO:0001578 8 7 0,000 0,0249591 0,09184947 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,0249591 0,09170275 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,0249591 0,09155649 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,0249591 0,0914107 ! leukocyte degranulation GO:0043299 10 7 0,000 0,0249591 0,09126537 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,0249591 0,09112051 ! reflex GO:0060004 12 7 0,000 0,0249591 0,0909761 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0249591 0,09083215 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,0249591 0,09068866 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0249591 0,09054561 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,0249591 0,09040302 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,0249591 0,09026088 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0249591 0,09011918 ! spinal cord patterning GO:0021511 7 7 0,000 0,0249591 0,08997793 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,0249591 0,08983712 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,0249591 0,08969675 ! adrenal gland development GO:0030325 17 7 0,000 0,0249591 0,08955682 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,0249591 0,08941732 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,0249591 0,08927826 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,0249591 0,08913963 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,0249591 0,08900142 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,0249591 0,08886365 ! endosome organization GO:0007032 10 7 0,000 0,0249591 0,0887263 ! thyroid hormone generation GO:0006590 11 7 0,000 0,0249591 0,08858938 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,0249591 0,08845288 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,0249591 0,0883168 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,0249591 0,08818114 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0249591 0,08804589 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,0249591 0,08791106 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0249591 0,08777663 ! galactose metabolic process GO:0006012 10 7 0,000 0,0249591 0,08764262 ! vesicle fusion GO:0006906 15 7 0,000 0,0249591 0,08750902 ! intracellular pH reduction GO:0051452 10 7 0,000 0,0249591 0,08737583 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,0249591 0,08724304 ! organ growth GO:0035265 11 7 0,000 0,0249591 0,08711065 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,0249591 0,08697867 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,0249591 0,08684708 ! retinol metabolic process GO:0042572 9 7 0,000 0,0249591 0,08671589 ! behavioral fear response GO:0001662 13 7 0,000 0,0249591 0,0865851 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,0249591 0,0864547 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,0249591 0,08632469 ! rRNA modification GO:0000154 12 7 0,000 0,0249591 0,08619507 ! protein heterooligomerization GO:0051291 10 7 0,000 0,0249591 0,08606585 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0249591 0,085937 ! response to UV-B GO:0010224 11 7 0,000 0,0249591 0,08580855 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,0249591 0,08568048 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,0249591 0,08555279 ! intermediate filament organization GO:0045109 11 7 0,000 0,0249591 0,08542547 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,0249591 0,08529854 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,0249591 0,08517199 ! fibrinolysis GO:0042730 9 7 0,000 0,0249591 0,08504581 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,0249591 0,08492 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,0249591 0,08479456 ! B cell lineage commitment GO:0002326 17 7 0,000 0,0249591 0,0846695 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,0249591 0,0845448 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,0249591 0,08442047 ! response to tropane GO:0014073 13 7 0,000 0,0249591 0,0842965 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,0249591 0,0841729 ! melanosome localization GO:0032400 10 7 0,000 0,0249591 0,08404966 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,0249591 0,08392678 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,0249591 0,08380426 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,0249591 0,0836821 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,0249591 0,08356029 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,0249591 0,08343884 ! mast cell activation GO:0045576 9 7 0,000 0,0249591 0,08331773 ! multicellular organismal aging GO:0010259 11 7 0,000 0,0249591 0,08319698 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,0249591 0,08307658 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,0249591 0,08295653 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,0249591 0,08283682 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,0249591 0,08271746 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,0249591 0,08259844 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,0249591 0,08247977 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,0249591 0,08236143 ! T cell lineage commitment GO:0002360 12 7 0,000 0,0249591 0,08224344 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,0249591 0,08212578 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,0249591 0,08200846 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,0249591 0,08189147 ! regulation of lipid transport GO:0032368 13 7 0,000 0,0249591 0,08177481 ! response to tumor cell GO:0002347 12 7 0,000 0,0249591 0,08165849 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,0249591 0,0815425 ! neuroblast proliferation GO:0007405 13 7 0,000 0,0249591 0,08142684 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,0249591 0,0813115 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,0249591 0,08119649 ! diuresis GO:0030146 12 7 0,000 0,0249591 0,08108181 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,0249591 0,08096745 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,0249591 0,08085341 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0249591 0,08073969 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,0249591 0,08062629 GO:0002688|regulation of leukocyte chemotaxis, ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0249591 0,08051321 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0249591 0,08040045 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,0249591 0,080288 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,0249591 0,08017586 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,0249591 0,08006404 ! lymph node development GO:0048535 9 7 0,000 0,0249591 0,07995253 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,0249591 0,07984133 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,0249591 0,07973044 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0249591 0,07961986 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,0249591 0,07950958 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,0249591 0,07939961 ! ATP catabolic process GO:0006200 10 7 0,000 0,0249591 0,07928994 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,0249591 0,07918058 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,0249591 0,07907151 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,0249591 0,07896275 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,0249591 0,07885428 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,0249591 0,07874612 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,0249591 0,07863825 ! muscle adaptation GO:0043500 12 7 0,000 0,0249591 0,07853067 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,0249591 0,07842339 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,0249591 0,0783164 ! retina homeostasis GO:0001895 9 7 0,000 0,0249591 0,0782097 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,0249591 0,07810329 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,0249591 0,07799717 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,0249591 0,07789134 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,0249591 0,0777858 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,0249591 0,07768054 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0249591 0,07757557 ! response to metal ion GO:0010038 103 70 1,000 0,02638092 0,08188408 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,02638092 0,08177373 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 1,000 0,02638092 0,08166367 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,02779367 0,08592128 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,02847426 0,08790712 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,02847426 0,08778929 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,02847426 0,08767176 ! axon extension GO:0048675 11 8 0,000 0,02847426 0,08755456 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,02847426 0,08743766 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,02847426 0,08732108 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,02847426 0,0872048 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,02847426 0,08708884 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,02847426 0,08697318 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,02847426 0,08685784 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,02847426 0,08674279 ! phosphate transport GO:0006817 10 8 0,000 0,02847426 0,08662805 ! N-glycan processing GO:0006491 12 8 0,000 0,02847426 0,08651362 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,02847426 0,08639948 ! UTP metabolic process GO:0046051 8 8 0,000 0,02847426 0,08628565 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,02847426 0,08617212 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,02847426 0,08605888 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,02847426 0,08594594 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,02847426 0,0858333 ! succinate metabolic process GO:0006105 14 8 0,000 0,02847426 0,08572095 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,02847426 0,0856089 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,02847426 0,08549714 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02847426 0,08538567 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,02847426 0,08527449 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,02847426 0,0851636 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,02847426 0,085053 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02847426 0,08494268 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,02847426 0,08483265 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,02847426 0,08472291 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,02847426 0,08461345 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,02847426 0,08450427 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,02847426 0,08439537 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,02847426 0,08428675 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,02847426 0,08417842 ! astrocyte differentiation GO:0048708 16 8 0,000 0,02847426 0,08407036 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,02847426 0,08396257 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,02847426 0,08385507 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,02847426 0,08374784 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,02847426 0,08364088 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,02847426 0,08353419 ! melanin metabolic process GO:0006582 12 8 0,000 0,02847426 0,08342778 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,02847426 0,08332164 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02847426 0,08321577 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,02847426 0,08311016 ! macrophage activation GO:0042116 12 8 0,000 0,02847426 0,08300483 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,02847426 0,08289976 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,02847426 0,08279495 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,02847426 0,08269041 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,02847426 0,08258614 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02847426 0,08248213 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,02847426 0,08237837 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,02847426 0,08227488 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,02847426 0,08217165 ! ruffle organization GO:0031529 11 8 0,000 0,02847426 0,08206868 ! osteoblast development GO:0002076 13 8 0,000 0,02847426 0,08196597 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,02847426 0,08186351 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,02847426 0,08176131 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,02847426 0,08165936 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,02847426 0,08155767 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,02847426 0,08145623 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,02847426 0,08135504 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,02847426 0,0812541 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,02847426 0,08115342 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,02847426 0,08105298 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,02847426 0,08095279 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,02847426 0,08085285 ! oligodendrocyte development GO:0014003 8 8 0,000 0,02847426 0,08075315 ! segment specification GO:0007379 10 8 0,000 0,02847426 0,0806537 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,02847426 0,0805545 ! cellular extravasation GO:0045123 11 8 0,000 0,02847426 0,08045554 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,02847426 0,08035682 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,02847426 0,08025834 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,02847426 0,08016011 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,02847426 0,08006211 ! snRNA metabolic process GO:0016073 10 8 0,000 0,02847426 0,07996436 GO:0016180|snRNA processing, ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,02847426 0,07986684 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,02847426 0,07976956 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,02847426 0,07967252 ! nucleosome disassembly GO:0006337 12 8 0,000 0,02847426 0,07957571 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,02847426 0,07947914 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,02847426 0,0793828 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,02847426 0,07928669 ! icosanoid secretion GO:0032309 12 8 0,000 0,02847426 0,07919082 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,02847426 0,07909518 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02847426 0,07899977 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,02847426 0,07890459 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,02847426 0,07880964 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,02847426 0,07871491 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,02847426 0,07862042 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,02847426 0,07852615 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,02847426 0,0784321 ! sterol catabolic process GO:0016127 9 8 0,000 0,02847426 0,07833829 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,02847426 0,07824469 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,02847426 0,07815132 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,02847426 0,07805817 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,02847426 0,07796525 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02847426 0,07787254 ! prophase GO:0051324 11 8 0,000 0,02847426 0,07778006 ! S phase GO:0051320 8 8 0,000 0,02847426 0,07768779 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,02847426 0,07759574 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,02847426 0,07750391 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,02847426 0,0774123 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,02847426 0,07732091 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,02847426 0,07722973 ! hormone catabolic process GO:0042447 13 8 0,000 0,02847426 0,07713876 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,02847426 0,07704801 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,02847426 0,07695747 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,02847426 0,07686715 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,02847426 0,07677703 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,02847426 0,07668713 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,02847426 0,07659744 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02847426 0,07650795 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,02847426 0,07641868 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,02847426 0,07632961 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,02847426 0,07624075 ! lamellipodium assembly GO:0030032 9 8 0,000 0,02847426 0,0761521 ! regulation of embryonic development GO:0045995 16 8 0,000 0,02847426 0,07606366 ! mitochondrion localization GO:0051646 12 8 0,000 0,02847426 0,07597541 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,02847426 0,07588738 ! mitochondrion organization GO:0007005 104 73 1,000 0,02851129 0,07589812 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 0,02851129 0,07581037 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,02923634 0,07764847 ! response to inorganic substance GO:0010035 115 75 1,000 0,02996874 0,07950184 ! response to nutrient GO:0007584 104 75 1,000 0,02996874 0,07941024 ! regulation of DNA binding GO:0051101 119 77 1,000 0,03145536 0,08325355 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,03197696 0,08453679 ! regulation of developmental growth GO:0048638 13 9 0,000 0,03197696 0,08443974 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,03197696 0,0843429 ! telencephalon cell migration GO:0022029 16 9 0,000 0,03197696 0,08424629 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,03197696 0,0841499 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,03197696 0,08405373 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,03197696 0,08395777 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,03197696 0,08386204 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03197696 0,08376653 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,03197696 0,08367123 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,03197696 0,08357615 ! GTP metabolic process GO:0046039 9 9 0,000 0,03197696 0,08348128 ! elastic fiber assembly GO:0048251 13 9 0,000 0,03197696 0,08338663 ! social behavior GO:0035176 14 9 0,000 0,03197696 0,0832922 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,03197696 0,08319798 ! artery development GO:0060840 19 9 0,000 0,03197696 0,08310397 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,03197696 0,08301017 ! regulation of glycolysis GO:0006110 15 9 0,000 0,03197696 0,08291658 ! response to pain GO:0048265 16 9 0,000 0,03197696 0,08282321 ! protein complex disassembly GO:0043241 17 9 0,000 0,03197696 0,08273004 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,03197696 0,08263709 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,03197696 0,08254434 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,03197696 0,0824518 ! lung alveolus development GO:0048286 17 9 0,000 0,03197696 0,08235947 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,03197696 0,08226735 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,03197696 0,08217543 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,03197696 0,08208372 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,03197696 0,08199221 ! ventral spinal cord development GO:0021517 11 9 0,000 0,03197696 0,0819009 ! protein targeting to ER GO:0045047 19 9 0,000 0,03197696 0,0818098 ! T cell selection GO:0045058 18 9 0,000 0,03197696 0,0817189 ! endoderm development GO:0007492 12 9 0,000 0,03197696 0,0816282 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,03197696 0,08153771 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,03197696 0,08144741 ! arginine catabolic process GO:0006527 10 9 0,000 0,03197696 0,08135731 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,03197696 0,08126741 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,03197696 0,08117772 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,03197696 0,08108821 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03197696 0,08099891 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,03197696 0,0809098 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,03197696 0,08082089 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,03197696 0,08073217 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,03197696 0,08064365 ! mannose metabolic process GO:0006013 9 9 0,000 0,03197696 0,08055532 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,03197696 0,08046719 ! receptor clustering GO:0043113 15 9 0,000 0,03197696 0,08037925 ! epithelial cell development GO:0002064 10 9 0,000 0,03197696 0,0802915 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,03197696 0,08020394 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,03197696 0,08011657 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,03197696 0,08002939 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,03197696 0,0799424 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,03197696 0,0798556 ! motor axon guidance GO:0008045 14 9 0,000 0,03197696 0,07976899 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,03197696 0,07968257 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,03197696 0,07959633 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,03197696 0,07951028 ! blastoderm segmentation GO:0007350 11 9 0,000 0,03197696 0,07942442 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,03197696 0,07933874 ! DNA ligation GO:0006266 14 9 0,000 0,03197696 0,07925324 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,03197696 0,07916793 ! response to amine stimulus GO:0014075 13 9 0,000 0,03197696 0,07908281 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,03197696 0,07899786 ! erythrocyte development GO:0048821 11 9 0,000 0,03197696 0,0789131 ! renal water homeostasis GO:0003091 14 9 0,000 0,03197696 0,07882852 ! postreplication repair GO:0006301 11 9 0,000 0,03197696 0,07874412 ! mRNA cleavage GO:0006379 13 9 0,000 0,03197696 0,0786599 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,03197696 0,07857587 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,03197696 0,07849201 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,03197696 0,07840833 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,03197696 0,07832482 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,03197696 0,0782415 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,03197696 0,07815835 ! acid secretion GO:0046717 14 9 0,000 0,03197696 0,07807538 ! musculoskeletal movement GO:0050881 11 9 0,000 0,03197696 0,07799259 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,03197696 0,07790997 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,03197696 0,07782752 ! purine base metabolic process GO:0006144 18 9 0,000 0,03197696 0,07774525 ! thymus development GO:0048538 15 9 0,000 0,03197696 0,07766316 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,03197696 0,07758123 ! spleen development GO:0048536 15 9 0,000 0,03197696 0,07749948 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,03197696 0,07741791 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,03197696 0,0773365 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,03197696 0,07725526 ! detection of calcium ion GO:0005513 13 9 0,000 0,03197696 0,0771742 ! blastocyst formation GO:0001825 12 9 0,000 0,03197696 0,0770933 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,03197696 0,07701258 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,03197696 0,07693202 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,03197696 0,07685163 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03197696 0,07677141 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,03197696 0,07669136 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,03197696 0,07661147 ! prepulse inhibition GO:0060134 14 9 0,000 0,03197696 0,07653175 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,03197696 0,07645219 ! insulin secretion GO:0030073 17 9 0,000 0,03197696 0,0763728 ! sequestering of metal ion GO:0051238 11 9 0,000 0,03197696 0,07629358 ! response to nicotine GO:0035094 16 9 0,000 0,03197696 0,07621452 ! establishment of cell polarity GO:0030010 12 9 0,000 0,03197696 0,07613562 ! nucleus localization GO:0051647 15 9 0,000 0,03197696 0,07605689 ! regulation of synapse organization GO:0050807 12 9 0,000 0,03197696 0,07597832 ! localization within membrane GO:0051668 15 9 0,000 0,03197696 0,07589991 ! forebrain development GO:0030900 131 80 1,000 0,03373897 0,07999963 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,03451425 0,08175363 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 1,000 0,03529647 0,08352045 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 1,000 0,03529647 0,08343461 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,03546723 0,08375218 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,03546723 0,08366628 ! neuron fate specification GO:0048665 11 10 0,000 0,03546723 0,08358056 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,03546723 0,08349501 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,03546723 0,08340964 ! thyroid gland development GO:0030878 19 10 0,000 0,03546723 0,08332444 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,03546723 0,08323941 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,03546723 0,08315456 ! synapsis GO:0007129 13 10 0,000 0,03546723 0,08306988 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,03546723 0,08298538 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,03546723 0,08290104 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,03546723 0,08281688 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,03546723 0,08273289 ! sulfate transport GO:0008272 12 10 0,000 0,03546723 0,08264906 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,03546723 0,08256541 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,03546723 0,08248193 ! androgen metabolic process GO:0008209 13 10 0,000 0,03546723 0,08239861 ! phospholipid efflux GO:0033700 16 10 0,000 0,03546723 0,08231547 ! hippocampus development GO:0021766 19 10 0,000 0,03546723 0,08223249 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,03546723 0,08214967 ! blood vessel remodeling GO:0001974 21 10 0,000 0,03546723 0,08206703 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,03546723 0,08198455 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,03546723 0,08190224 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,03546723 0,08182009 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,03546723 0,0817381 ! pathogenesis GO:0009405 13 10 0,000 0,03546723 0,08165628 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,03546723 0,08157463 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03546723 0,08149313 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,03546723 0,0814118 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,03546723 0,08133063 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,03546723 0,08124963 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,03546723 0,08116878 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,03546723 0,0810881 ! melanocyte differentiation GO:0030318 15 10 0,000 0,03546723 0,08100757 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,03546723 0,08092721 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,03546723 0,080847 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03546723 0,08076696 ! response to X-ray GO:0010165 16 10 0,000 0,03546723 0,08068707 ! B cell proliferation GO:0042100 14 10 0,000 0,03546723 0,08060734 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,03546723 0,08052777 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,03546723 0,08044835 ! forebrain cell migration GO:0021885 17 10 0,000 0,03546723 0,08036909 ! lipid digestion GO:0044241 15 10 0,000 0,03546723 0,08028999 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,03546723 0,08021104 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,03546723 0,08013225 ! UV protection GO:0009650 14 10 0,000 0,03546723 0,08005361 ! entry into host cell GO:0030260 20 10 0,000 0,03546723 0,07997512 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,03546723 0,07989679 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,03546723 0,07981862 ! negative regulation of ossification GO:0030279 19 10 0,000 0,03546723 0,07974059 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,03546723 0,07966272 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,03546723 0,079585 ! regulation of bone resorption GO:0045124 24 10 0,000 0,03546723 0,07950743 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,03546723 0,07943002 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,03546723 0,07935275 ! regulation of organ growth GO:0046620 11 10 0,000 0,03546723 0,07927563 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,03546723 0,07919867 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03546723 0,07912185 ! embryonic axis specification GO:0000578 12 10 0,000 0,03546723 0,07904518 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,03546723 0,07896866 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,03546723 0,07889229 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,03546723 0,07881606 ! cranial nerve development GO:0021545 12 10 0,000 0,03546723 0,07873999 ! fucose catabolic process GO:0019317 16 10 0,000 0,03546723 0,07866406 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,03546723 0,07858827 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,03546723 0,07851263 ! protein sumoylation GO:0016925 12 10 0,000 0,03546723 0,07843714 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03546723 0,07836179 ! zymogen activation GO:0031638 14 10 0,000 0,03546723 0,07828659 ! salivary gland development GO:0007431 22 10 0,000 0,03546723 0,07821153 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03546723 0,07813662 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,03546723 0,07806184 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,03546723 0,07798721 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,03546723 0,07791273 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,03546723 0,07783838 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,03546723 0,07776418 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03546723 0,07769012 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,03546723 0,0776162 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,03546723 0,07754242 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,03546723 0,07746878 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,03546723 0,07739528 ! detection of bacterium GO:0016045 10 10 0,000 0,03546723 0,07732192 ! embryonic gut development GO:0048566 11 10 0,000 0,03546723 0,0772487 ! activation of innate immune response GO:0002218 10 10 0,000 0,03546723 0,07717562 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,03546723 0,07710267 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,03546723 0,07702986 ! developmental induction GO:0031128 13 10 0,000 0,03546723 0,07695719 GO:0045168|cell-cell signaling involved in cell fate specification, ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,03546723 0,07688466 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,03546723 0,07681227 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,03546723 0,07674001 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,03768417 0,08146015 ! cell cycle arrest GO:0007050 150 86 1,000 0,03849357 0,08313165 ! rRNA transcription GO:0009303 17 11 0,000 0,03894511 0,08402791 ! respiratory burst GO:0045730 14 11 0,000 0,03894511 0,08394916 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,03894511 0,08387056 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,03894511 0,0837921 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,03894511 0,08371379 ! virus-host interaction GO:0019048 17 11 0,000 0,03894511 0,08363563 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,03894511 0,08355761 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,03894511 0,08347974 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,03894511 0,08340201 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,03894511 0,08332442 ! RNA polyadenylation GO:0043631 19 11 0,000 0,03894511 0,08324699 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,03894511 0,08316969 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 14 11 0,000 0,03894511 0,08309254 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,03894511 0,08301553 ! T cell proliferation GO:0042098 20 11 0,000 0,03894511 0,08293866 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,03894511 0,08286194 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,03894511 0,08278536 ! bone resorption GO:0045453 16 11 0,000 0,03894511 0,08270892 ! regulated secretory pathway GO:0045055 14 11 0,000 0,03894511 0,08263262 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,03894511 0,08255646 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,03894511 0,08248044 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,03894511 0,08240456 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,03894511 0,08232882 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,03894511 0,08225322 ! syncytium formation GO:0006949 15 11 0,000 0,03894511 0,08217776 ! plasma membrane organization GO:0007009 18 11 0,000 0,03894511 0,08210243 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,03894511 0,08202725 ! focal adhesion formation GO:0048041 24 11 0,000 0,03894511 0,0819522 ! mitotic spindle organization GO:0007052 15 11 0,000 0,03894511 0,08187729 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,03894511 0,08180252 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,03894511 0,08172788 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,03894511 0,08165338 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,03894511 0,08157901 ! adult heart development GO:0007512 11 11 0,000 0,03894511 0,08150478 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,03894511 0,08143069 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,03894511 0,08135673 ! temperature homeostasis GO:0001659 16 11 0,000 0,03894511 0,0812829 ! L-glutamate transport GO:0015813 16 11 0,000 0,03894511 0,08120921 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,03894511 0,08113565 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,03894511 0,08106222 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,03894511 0,08098893 ! stem cell development GO:0048864 29 11 0,000 0,03894511 0,08091577 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,03894511 0,08084274 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,03894511 0,08076984 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,03894511 0,08069708 ! vasoconstriction GO:0042310 15 11 0,000 0,03894511 0,08062444 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,03894511 0,08055194 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,03894511 0,08047957 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,03894511 0,08040732 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,03894511 0,08033521 ! ribosome assembly GO:0042255 13 11 0,000 0,03894511 0,08026322 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,03894511 0,08019137 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,03894511 0,08011964 ! chromatin silencing GO:0006342 19 11 0,000 0,03894511 0,08004804 ! nucleosome positioning GO:0016584 13 11 0,000 0,03894511 0,07997657 ! T cell homeostasis GO:0043029 20 11 0,000 0,03894511 0,07990522 ! regulation of isotype switching GO:0045191 19 11 0,000 0,03894511 0,07983401 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,03894511 0,07976292 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,03894511 0,07969195 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,03894511 0,07962112 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,03894511 0,07955041 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,03894511 0,07947982 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,03894511 0,07940936 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,03894511 0,07933902 ! male genitalia development GO:0030539 13 11 0,000 0,03894511 0,07926881 ! cholesterol efflux GO:0033344 19 11 0,000 0,03894511 0,07919872 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,03894511 0,07912876 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,03894511 0,07905892 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,03894511 0,0789892 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,03894511 0,07891961 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,03894511 0,07885014 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,03894511 0,07878079 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,03894511 0,07871156 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,03894511 0,07864245 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,03894511 0,07857347 ! lysogeny GO:0030069 18 11 0,000 0,03894511 0,07850461 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,03894511 0,07843586 ! acrosome reaction GO:0007340 13 11 0,000 0,03894511 0,07836724 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,03894511 0,07829874 ! protein processing GO:0016485 114 88 1,000 0,04013225 0,080615 ! regulation of T cell activation GO:0050863 128 89 1,000 0,04096143 0,0822088 ! lactation GO:0007595 20 12 0,000 0,04241065 0,08504316 ! reproductive cellular process GO:0048610 14 12 0,000 0,04241065 0,08496908 ! tRNA modification GO:0006400 14 12 0,000 0,04241065 0,08489513 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,04241065 0,0848213 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,04241065 0,08474761 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,04241065 0,08467404 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,04241065 0,08460061 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,04241065 0,0845273 ! non-recombinational repair GO:0000726 19 12 0,000 0,04241065 0,08445411 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,04241065 0,08438105 ! peroxisomal transport GO:0043574 21 12 0,000 0,04241065 0,08430812 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,04241065 0,08423532 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,04241065 0,08416264 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,04241065 0,08409009 ! heart looping GO:0001947 15 12 0,000 0,04241065 0,08401766 ! palate development GO:0060021 15 12 0,000 0,04241065 0,08394535 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,04241065 0,08387317 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,04241065 0,08380112 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,04241065 0,08372918 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,04241065 0,08365737 ! arginine metabolic process GO:0006525 13 12 0,000 0,04241065 0,08358569 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,04241065 0,08351413 ! methionine metabolic process GO:0006555 13 12 0,000 0,04241065 0,08344269 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,04241065 0,08337137 ! Golgi organization GO:0007030 18 12 0,000 0,04241065 0,08330017 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,04241065 0,08322909 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,04241065 0,08315814 ! monoamine transport GO:0015844 13 12 0,000 0,04241065 0,08308731 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04241065 0,0830166 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,04241065 0,082946 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,04241065 0,08287553 ! L-amino acid transport GO:0015807 20 12 0,000 0,04241065 0,08280518 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,04241065 0,08273494 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,04241065 0,08266483 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,04241065 0,08259483 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04241065 0,08252496 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,04241065 0,0824552 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,04241065 0,08238556 ! cerebellum development GO:0021549 13 12 0,000 0,04241065 0,08231603 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,04241065 0,08224663 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,04241065 0,08217734 ! histone acetylation GO:0016573 23 12 0,000 0,04241065 0,08210816 ! histone methylation GO:0016571 15 12 0,000 0,04241065 0,08203911 ! autonomic nervous system development GO:0048483 23 12 0,000 0,04241065 0,08197017 ! gland morphogenesis GO:0022612 23 12 0,000 0,04241065 0,08190134 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,04241065 0,08183263 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,04241065 0,08176404 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,04241065 0,08169556 ! response to gamma radiation GO:0010332 20 12 0,000 0,04241065 0,0816272 ! regulation of epidermis development GO:0045682 17 12 0,000 0,04241065 0,08155895 ! intestinal absorption GO:0050892 19 12 0,000 0,04241065 0,08149081 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,04241065 0,08142279 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,04241065 0,08135488 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,04241065 0,08128708 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,04241065 0,0812194 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,04241065 0,08115183 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,04241065 0,08108437 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,04241065 0,08101703 ! microspike assembly GO:0030035 23 12 0,000 0,04241065 0,08094979 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,04241065 0,08088267 ! response to cold GO:0009409 14 12 0,000 0,04241065 0,08081566 ! cell fate commitment GO:0045165 141 92 1,000 0,04348762 0,08279927 ! positive regulation of immune response GO:0050778 121 92 1,000 0,04348762 0,08273079 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,04586389 0,0871793 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,04586389 0,08710731 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,04586389 0,08703544 ! cGMP metabolic process GO:0046068 16 13 0,000 0,04586389 0,08696369 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,04586389 0,08689205 ! water transport GO:0006833 17 13 0,000 0,04586389 0,08682054 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,04586389 0,08674914 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,04586389 0,08667786 ! lipid localization GO:0010876 24 13 0,000 0,04586389 0,0866067 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,04586389 0,08653565 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,04586389 0,08646472 ! organelle fusion GO:0048284 28 13 0,000 0,04586389 0,0863939 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,04586389 0,0863232 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,04586389 0,08625262 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,04586389 0,08618215 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,04586389 0,0861118 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,04586389 0,08604156 ! response to hexose stimulus GO:0009746 19 13 0,000 0,04586389 0,08597144 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,04586389 0,08590143 ! glutamate metabolic process GO:0006536 18 13 0,000 0,04586389 0,08583153 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,04586389 0,08576175 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,04586389 0,08569208 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,04586389 0,08562253 ! NAD metabolic process GO:0019674 21 13 0,000 0,04586389 0,08555309 ! exocrine system development GO:0035272 27 13 0,000 0,04586389 0,08548376 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,04586389 0,08541454 ! bone mineralization GO:0030282 15 13 0,000 0,04586389 0,08534543 ! regulation of exocytosis GO:0017157 17 13 0,000 0,04586389 0,08527644 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,04586389 0,08520756 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,04586389 0,08513879 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,04586389 0,08507012 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,04586389 0,08500158 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,04586389 0,08493314 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,04586389 0,08486481 ! genitalia development GO:0048806 15 13 0,000 0,04586389 0,08479659 ! regulation of cellular pH GO:0030641 20 13 0,000 0,04586389 0,08472848 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,04586389 0,08466048 ! cellular pigmentation GO:0033059 24 13 0,000 0,04586389 0,08459259 ! tissue regeneration GO:0042246 21 13 0,000 0,04586389 0,0845248 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,04586389 0,08445713 ! cofactor transport GO:0051181 19 13 0,000 0,04586389 0,08438956 ! NADP metabolic process GO:0006739 18 13 0,000 0,04586389 0,08432211 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,04586389 0,08425476 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,04586389 0,08418751 ! gas transport GO:0015669 18 13 0,000 0,04586389 0,08412038 ! regulation of RNA stability GO:0043487 28 13 0,000 0,04586389 0,08405335 ! heme biosynthetic process GO:0006783 20 13 0,000 0,04586389 0,08398643 ! regulation of axon extension GO:0030516 23 13 0,000 0,04586389 0,08391961 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,04586389 0,08385291 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,04586389 0,0837863 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,04586389 0,08371981 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,04586389 0,08365341 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,04586389 0,08358713 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,04586389 0,08352095 ! angiogenesis GO:0001525 149 95 1,000 0,04607065 0,08383108 ! in utero embryonic development GO:0001701 147 96 1,000 0,04694403 0,08535278 ! protein maturation GO:0051604 129 96 1,000 0,04694403 0,08528536 ! response to light stimulus GO:0009416 153 96 1,000 0,04694403 0,08521805 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,04930488 0,08943314 ! superoxide anion generation GO:0042554 18 14 0,000 0,04930488 0,08936266 ! neuron maturation GO:0042551 21 14 0,000 0,04930488 0,0892923 ! regulation of S phase GO:0033261 18 14 0,000 0,04930488 0,08922205 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,04930488 0,0891519 ! myotube differentiation GO:0014902 21 14 0,000 0,04930488 0,08908187 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,04930488 0,08901195 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,04930488 0,08894213 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,04930488 0,08887243 ! inositol metabolic process GO:0006020 20 14 0,000 0,04930488 0,08880284 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,04930488 0,08873335 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,04930488 0,08866397 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,04930488 0,0885947 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,04930488 0,08852554 ! gene silencing by RNA GO:0031047 20 14 0,000 0,04930488 0,08845649 ! response to cAMP GO:0051591 19 14 0,000 0,04930488 0,08838755 ! limbic system development GO:0021761 25 14 0,000 0,04930488 0,08831871 ! startle response GO:0001964 21 14 0,000 0,04930488 0,08824998 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,04930488 0,08818135 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,04930488 0,08811284 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,04930488 0,08804443 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,04930488 0,08797612 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,04930488 0,08790792 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,04930488 0,08783983 ! glycine metabolic process GO:0006544 22 14 0,000 0,04930488 0,08777184 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,04930488 0,08770396 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,04930488 0,08763618 ! regulation of heart rate GO:0002027 23 14 0,000 0,04930488 0,08756851 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,04930488 0,08750094 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,04930488 0,08743348 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,04930488 0,08736612 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,04930488 0,08729886 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,04930488 0,08723171 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,04930488 0,08716466 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,04930488 0,08709771 ! axon cargo transport GO:0008088 27 14 0,000 0,04930488 0,08703087 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,04930488 0,08696413 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,04930488 0,08689749 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,04930488 0,08683095 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,04930488 0,08676452 ! mRNA splice site selection GO:0006376 26 14 0,000 0,04930488 0,08669818 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,04930488 0,08663195 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,04930488 0,08656582 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,04930488 0,08649979 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,04930488 0,08643386 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,04930488 0,08636803 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,04930488 0,0863023 ! muscle maintenance GO:0046716 19 14 0,000 0,04930488 0,08623667 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,04930488 0,08617114 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,04930488 0,08610571 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,04930488 0,08604038 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,04930488 0,08597515 ! cell killing GO:0001906 20 14 0,000 0,04930488 0,08591002 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,04930488 0,08584498 ! cilium assembly GO:0042384 20 14 0,000 0,04930488 0,08578005 ! peptide hormone secretion GO:0030072 23 14 0,000 0,04930488 0,08571521 ! regulation of translation GO:0006417 151 100 1,000 0,050498 0,08772311 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,050498 0,08765691 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,05273365 0,09146863 ! positive regulation of cell size GO:0045793 20 15 0,000 0,05273365 0,0913997 ! metencephalon development GO:0022037 19 15 0,000 0,05273365 0,09133087 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,05273365 0,09126215 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,05273365 0,09119353 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,05273365 0,09112502 ! skin development GO:0043588 25 15 0,000 0,05273365 0,0910566 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,05273365 0,0909883 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,05273365 0,09092009 ! lipid phosphorylation GO:0046834 23 15 0,000 0,05273365 0,09085198 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,05273365 0,09078398 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,05273365 0,09071608 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,05273365 0,09064828 ! bile acid metabolic process GO:0008206 22 15 0,000 0,05273365 0,09058058 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,05273365 0,09051298 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,05273365 0,09044549 ! adult walking behavior GO:0007628 25 15 0,000 0,05273365 0,09037809 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,05273365 0,09031079 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,05273365 0,0902436 ! myoblast differentiation GO:0045445 27 15 0,000 0,05273365 0,0901765 ! centrosome cycle GO:0007098 16 15 0,000 0,05273365 0,09010951 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,05273365 0,09004261 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,05273365 0,08997581 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,05273365 0,08990912 ! cerebral cortex development GO:0021987 29 15 0,000 0,05273365 0,08984252 ! response to osmotic stress GO:0006970 22 15 0,000 0,05273365 0,08977602 ! vesicle coating GO:0006901 25 15 0,000 0,05273365 0,08970961 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,05273365 0,08964331 ! DNA integration GO:0015074 22 15 0,000 0,05273365 0,0895771 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,05273365 0,08951099 ! peptide secretion GO:0002790 27 15 0,000 0,05273365 0,08944498 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,05273365 0,08937907 ! regulation of vasodilation GO:0042312 24 15 0,000 0,05273365 0,08931325 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,05273365 0,08924753 ! neuron recognition GO:0008038 22 15 0,000 0,05273365 0,08918191 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,05273365 0,08911638 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,05273365 0,08905095 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,05273365 0,08898562 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,05273365 0,08892038 ! biomineral formation GO:0031214 18 15 0,000 0,05273365 0,08885524 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,05273365 0,08879019 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,05273365 0,08872524 ! dopamine metabolic process GO:0042417 30 15 0,000 0,05273365 0,08866038 ! organic cation transport GO:0015695 19 15 0,000 0,05273365 0,08859562 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,05273365 0,08853095 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,05273365 0,08846637 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,05273365 0,08840189 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 27 15 0,000 0,05273365 0,08833751 ! peptide hormone processing GO:0016486 19 15 0,000 0,05273365 0,08827321 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,05273365 0,08820902 ! protein secretion GO:0009306 27 16 0,000 0,05615025 0,0938558 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,05615025 0,09378764 ! hormone secretion GO:0046879 25 16 0,000 0,05615025 0,09371958 ! bone remodeling GO:0046849 24 16 0,000 0,05615025 0,09365162 ! endothelial cell migration GO:0043542 22 16 0,000 0,05615025 0,09358375 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,05615025 0,09351599 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,05615025 0,09344832 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,05615025 0,09338075 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,05615025 0,09331328 ! glial cell development GO:0021782 24 16 0,000 0,05615025 0,09324591 ! patterning of blood vessels GO:0001569 24 16 0,000 0,05615025 0,09317863 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,05615025 0,09311145 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,05615025 0,09304437 ! protein polyubiquitination GO:0000209 26 16 0,000 0,05615025 0,09297738 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,05615025 0,09291049 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,05615025 0,0928437 ! fructose metabolic process GO:0006000 20 16 0,000 0,05615025 0,092777 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,05615025 0,0927104 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,05615025 0,09264389 ! protein export from nucleus GO:0006611 24 16 0,000 0,05615025 0,09257748 ! negative regulation of immune response GO:0050777 28 16 0,000 0,05615025 0,09251116 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,05615025 0,09244494 ! DNA replication initiation GO:0006270 25 16 0,000 0,05615025 0,09237881 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,05615025 0,09231278 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,05615025 0,09224684 ! neural crest cell migration GO:0001755 24 16 0,000 0,05615025 0,092181 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,05615025 0,09211525 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,05615025 0,09204959 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,05615025 0,09198403 ! steroid catabolic process GO:0006706 22 16 0,000 0,05615025 0,09191856 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,05615025 0,09185319 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,05615025 0,0917879 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,05615025 0,09172271 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,05615025 0,09165762 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,05615025 0,09159261 ! sperm-egg recognition GO:0035036 16 16 0,000 0,05615025 0,0915277 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,05615025 0,09146288 ! nerve development GO:0021675 18 16 0,000 0,05615025 0,09139815 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,05615025 0,09133351 ! negative regulation of translation GO:0017148 22 16 0,000 0,05615025 0,09126896 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,05955473 0,09673437 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,05955473 0,0966661 ! negative regulation of defense response GO:0031348 19 17 0,000 0,05955473 0,09659793 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,05955473 0,09652986 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,05955473 0,09646188 ! glycerol metabolic process GO:0006071 20 17 0,000 0,05955473 0,096394 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,05955473 0,09632621 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,05955473 0,09625852 ! signal complex assembly GO:0007172 29 17 0,000 0,05955473 0,09619092 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,05955473 0,09612342 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,05955473 0,09605601 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,05955473 0,0959887 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,05955473 0,09592148 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,05955473 0,09585435 ! memory GO:0007613 25 17 0,000 0,05955473 0,09578732 ! keratinization GO:0031424 17 17 0,000 0,05955473 0,09572038 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,05955473 0,09565354 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,05955473 0,09558679 ! retinoid metabolic process GO:0001523 22 17 0,000 0,05955473 0,09552013 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,05955473 0,09545357 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,05955473 0,0953871 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,05955473 0,09532072 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,05955473 0,09525443 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,05955473 0,09518823 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,05955473 0,09512213 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,05955473 0,09505612 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,05955473 0,0949902 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,05955473 0,09492437 ! membrane budding GO:0006900 29 17 0,000 0,05955473 0,09485864 ! heme metabolic process GO:0042168 27 17 0,000 0,05955473 0,09479299 ! actin filament bundle formation GO:0051017 26 17 0,000 0,05955473 0,09472743 ! neuromuscular junction development GO:0007528 23 17 0,000 0,05955473 0,09466197 ! body fluid secretion GO:0007589 27 17 0,000 0,05955473 0,0945966 ! stem cell differentiation GO:0048863 36 17 0,000 0,05955473 0,09453131 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,05955473 0,09446612 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,05955473 0,09440101 ! sensory perception of pain GO:0019233 23 17 0,000 0,05955473 0,094336 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,05955473 0,09427107 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,05955473 0,09420624 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,05955473 0,09414149 ! synaptogenesis GO:0007416 24 17 0,000 0,05955473 0,09407683 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,05955473 0,09401226 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,05955473 0,09394778 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,05955473 0,09388339 ! cell-cell junction organization GO:0045216 25 17 0,000 0,05955473 0,09381909 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,05955473 0,09375487 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,05955473 0,09369075 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,05955473 0,09362671 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,05955473 0,09356275 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,05955473 0,09349889 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,05955473 0,09343511 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,06294711 0,09869009 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,06294711 0,09862286 ! positive regulation of translation GO:0045727 28 18 0,000 0,06294711 0,09855573 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,06294711 0,09848868 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,06294711 0,09842173 ! cAMP metabolic process GO:0046058 33 18 0,000 0,06294711 0,09835487 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,06294711 0,09828809 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,06294711 0,09822141 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,06294711 0,09815482 ! axis specification GO:0009798 26 18 0,000 0,06294711 0,09808832 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,06294711 0,09802191 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,06294711 0,09795559 ! pancreas development GO:0031016 26 18 0,000 0,06294711 0,09788936 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,06294711 0,09782322 ! glutamine metabolic process GO:0006541 23 18 0,000 0,06294711 0,09775717 ! pigmentation during development GO:0048066 31 18 0,000 0,06294711 0,0976912 ! central nervous system neuron development GO:0021954 30 18 0,000 0,06294711 0,09762533 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,06294711 0,09755954 ! fucose metabolic process GO:0006004 26 18 0,000 0,06294711 0,09749385 ! response to fungus GO:0009620 19 18 0,000 0,06294711 0,09742824 ! peptide cross-linking GO:0018149 31 18 0,000 0,06294711 0,09736272 ! heart process GO:0003015 27 18 0,000 0,06294711 0,09729729 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,06294711 0,09723194 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,06294711 0,09716669 ! visual learning GO:0008542 35 18 0,000 0,06294711 0,09710152 ! somitogenesis GO:0001756 24 18 0,000 0,06294711 0,09703644 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,06294711 0,09697144 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,06294711 0,09690653 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,06294711 0,09684171 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,06294711 0,09677698 ! vitamin transport GO:0051180 24 18 0,000 0,06294711 0,09671233 ! hormone transport GO:0009914 27 18 0,000 0,06294711 0,09664777 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,06294711 0,0965833 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,06294711 0,09651891 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,06294711 0,0964546 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,06294711 0,09639039 ! cell-cell recognition GO:0009988 20 18 0,000 0,06294711 0,09632626 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,06294711 0,09626221 ! regulation of glucose import GO:0046324 21 18 0,000 0,06294711 0,09619825 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,06294711 0,09613437 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,06294711 0,09607058 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,06294711 0,09600687 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,06294711 0,09594325 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,06632746 0,10102858 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,06632746 0,10096172 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,06632746 0,10089494 ! positive regulation of ossification GO:0045778 30 19 0,000 0,06632746 0,10082826 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,06632746 0,10076166 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,06632746 0,10069515 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,06632746 0,10062873 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,06632746 0,1005624 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,06632746 0,10049615 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,06632746 0,10042999 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,06632746 0,10036392 ! regeneration GO:0031099 32 19 0,000 0,06632746 0,10029793 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,06632746 0,10023203 ! sensory perception of taste GO:0050909 23 19 0,000 0,06632746 0,10016622 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,06632746 0,10010049 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,06632746 0,10003485 ! smooth muscle contraction GO:0006939 36 19 0,000 0,06632746 0,0999693 ! peroxisome organization GO:0007031 29 19 0,000 0,06632746 0,09990383 ! digestive system process GO:0022600 30 19 0,000 0,06632746 0,09983845 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,06632746 0,09977315 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,06632746 0,09970794 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,06632746 0,09964282 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,06632746 0,09957778 ! sex determination GO:0007530 29 19 0,000 0,06632746 0,09951282 ! plasma membrane fusion GO:0045026 23 19 0,000 0,06632746 0,09944795 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,06632746 0,09938316 ! cytolysis GO:0019835 20 19 0,000 0,06632746 0,09931846 ! renal system process GO:0003014 35 19 0,000 0,06632746 0,09925384 ! vasodilation GO:0042311 33 19 0,000 0,06632746 0,09918931 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,06632746 0,09912486 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,06632746 0,09906049 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,06632746 0,09899621 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,06632746 0,09893201 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,06632746 0,09886789 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,06632746 0,09880386 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,06632746 0,09873991 ! sarcomere organization GO:0045214 23 19 0,000 0,06632746 0,09867604 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,06632746 0,09861225 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,06632746 0,09854855 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,06632746 0,09848493 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,06632746 0,09842139 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,06632746 0,09835793 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,06632746 0,09829456 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,06632746 0,09823126 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,06632746 0,09816805 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,0696958 0,10308704 ! iron ion transport GO:0006826 37 20 0,000 0,0696958 0,10302079 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,0696958 0,10295462 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,0696958 0,10288854 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,0696958 0,10282254 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,0696958 0,10275663 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,0696958 0,1026908 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,0696958 0,10262506 ! spinal cord development GO:0021510 31 20 0,000 0,0696958 0,1025594 ! response to ethanol GO:0045471 37 20 0,000 0,0696958 0,10249382 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,0696958 0,10242833 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,0696958 0,10236293 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,0696958 0,1022976 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,0696958 0,10223236 ! chromosome condensation GO:0030261 31 20 0,000 0,0696958 0,1021672 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,0696958 0,10210213 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,0696958 0,10203714 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,0696958 0,10197223 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,0696958 0,1019074 ! pallium development GO:0021543 38 20 0,000 0,0696958 0,10184266 ! DNA modification GO:0006304 28 20 0,000 0,0696958 0,10177799 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,0696958 0,10171341 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,0696958 0,10164892 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,0696958 0,1015845 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,0696958 0,10152017 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,0696958 0,10145591 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,0696958 0,10139174 ! collagen catabolic process GO:0030574 25 20 0,000 0,0696958 0,10132765 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,0696958 0,10126364 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,0696958 0,10119971 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,0696958 0,10113586 ! alditol metabolic process GO:0019400 24 20 0,000 0,0696958 0,10107209 ! actin filament-based movement GO:0030048 34 20 0,000 0,0696958 0,10100841 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,07305218 0,10580606 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,07305218 0,10573947 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,07305218 0,10567297 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,07305218 0,10560655 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,07305218 0,10554022 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,07305218 0,10547396 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,07305218 0,10540779 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,07305218 0,10534171 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,07305218 0,1052757 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,07305218 0,10520978 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,07305218 0,10514394 ! protein amino acid acylation GO:0043543 37 21 0,000 0,07305218 0,10507819 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,07305218 0,10501251 ! vesicle docking GO:0048278 27 21 0,000 0,07305218 0,10494692 ! phototransduction GO:0007602 25 21 0,000 0,07305218 0,10488141 ! dendrite development GO:0016358 35 21 0,000 0,07305218 0,10481598 ! visual behavior GO:0007632 39 21 0,000 0,07305218 0,10475064 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,07305218 0,10468537 ! ovarian follicle development GO:0001541 30 21 0,000 0,07305218 0,10462019 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,07305218 0,10455509 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,07305218 0,10449006 GO:0042278|purine nucleoside metabolic process, ! cell aging GO:0007569 32 21 0,000 0,07305218 0,10442512 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,07305218 0,10436026 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,07305218 0,10429548 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,07305218 0,10423078 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,07305218 0,10416616 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,07305218 0,10410163 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,07305218 0,10403717 ! fatty acid transport GO:0015908 30 21 0,000 0,07305218 0,10397279 ! immunoglobulin production GO:0002377 33 21 0,000 0,07305218 0,10390849 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,07305218 0,10384427 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,07305218 0,10378013 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,07305218 0,10371606 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,07305218 0,10365208 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,07305218 0,10358818 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,07305218 0,10352435 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,07305218 0,10346061 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,07305218 0,10339694 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,07305218 0,10333335 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,07305218 0,10326984 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,07305218 0,1032064 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,07305218 0,10314305 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,07305218 0,10307977 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,07639665 0,10773286 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,07639665 0,10766685 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,07639665 0,10760091 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,07639665 0,10753506 ! viral genome replication GO:0019079 29 22 0,000 0,07639665 0,10746929 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,07639665 0,1074036 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,07639665 0,10733799 ! leukocyte adhesion GO:0007159 38 22 0,000 0,07639665 0,10727246 ! molting cycle process GO:0022404 40 22 0,000 0,07639665 0,10720701 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,07639665 0,10714164 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,07639665 0,10707635 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,07639665 0,10701114 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,07639665 0,10694601 ! vasculogenesis GO:0001570 33 22 0,000 0,07639665 0,10688096 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,07639665 0,10681598 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,07639665 0,10675109 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,07639665 0,10668627 ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,07639665 0,10662154 ! lysosome organization GO:0007040 37 22 0,000 0,07639665 0,10655688 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,07639665 0,1064923 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,07639665 0,1064278 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,07639665 0,10636337 ! regulation of behavior GO:0050795 38 22 0,000 0,07639665 0,10629903 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,07639665 0,10623476 ! membrane depolarization GO:0051899 35 22 0,000 0,07639665 0,10617057 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,07639665 0,10610646 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,07639665 0,10604242 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,07639665 0,10597846 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,07639665 0,10591458 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,07639665 0,10585078 ! blastocyst development GO:0001824 37 22 0,000 0,07639665 0,10578705 ! neural tube closure GO:0001843 33 22 0,000 0,07639665 0,1057234 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,07639665 0,10565983 ! protein tetramerization GO:0051262 39 22 0,000 0,07639665 0,10559633 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,07972924 0,11013649 ! neuron fate commitment GO:0048663 32 23 0,000 0,07972924 0,11007038 ! embryonic pattern specification GO:0009880 31 23 0,000 0,07972924 0,11000435 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,07972924 0,1099384 ! myelination GO:0042552 35 23 0,000 0,07972924 0,10987253 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,07972924 0,10980674 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,07972924 0,10974102 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,07972924 0,10967539 ! vesicle targeting GO:0006903 32 23 0,000 0,07972924 0,10960983 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,07972924 0,10954435 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,07972924 0,10947896 ! osteoblast differentiation GO:0001649 40 23 0,000 0,07972924 0,10941363 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,07972924 0,10934839 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,07972924 0,10928322 ! interaction with host GO:0051701 37 23 0,000 0,07972924 0,10921814 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,07972924 0,10915312 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,07972924 0,10908819 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,07972924 0,10902334 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,07972924 0,10895856 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,07972924 0,10889385 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,07972924 0,10882923 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,07972924 0,10876468 ! pentose metabolic process GO:0019321 31 23 0,000 0,07972924 0,10870021 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,07972924 0,10863581 ! spermatid development GO:0007286 33 23 0,000 0,07972924 0,10857149 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,07972924 0,10850725 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,07972924 0,10844308 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,07972924 0,10837899 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,07972924 0,10831497 ! telomere organization GO:0032200 32 23 0,000 0,07972924 0,10825103 GO:0000723|telomere maintenance, ! regulation of amine transport GO:0051952 38 23 0,000 0,07972924 0,10818717 ! liver development GO:0001889 40 23 0,000 0,07972924 0,10812338 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,08304999 0,11256039 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,08304999 0,1124941 ! initiation of viral infection GO:0019059 42 24 0,000 0,08304999 0,11242789 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,08304999 0,11236176 ! superoxide metabolic process GO:0006801 32 24 0,000 0,08304999 0,1122957 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,08304999 0,11222972 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,08304999 0,11216382 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,08304999 0,112098 ! sperm motility GO:0030317 27 24 0,000 0,08304999 0,11203225 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,08304999 0,11196658 ! vacuole organization GO:0007033 39 24 0,000 0,08304999 0,11190099 ! receptor metabolic process GO:0043112 37 24 0,000 0,08304999 0,11183547 ! neural crest cell development GO:0014032 39 24 0,000 0,08304999 0,11177003 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,08304999 0,11170467 ! primary neural tube formation GO:0014020 35 24 0,000 0,08304999 0,11163938 ! negative regulation of cell development GO:0010721 56 24 0,000 0,08304999 0,11157417 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 0,000 0,08304999 0,11150904 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,08304999 0,11144398 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,08304999 0,111379 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,08304999 0,11131409 ! glutathione metabolic process GO:0006749 29 24 0,000 0,08304999 0,11124926 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,08304999 0,11118451 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,08304999 0,11111983 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,08304999 0,11105522 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,08635896 0,1154129 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,08635896 0,11534588 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,08635896 0,11527893 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,08635896 0,11521206 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,08635896 0,11514527 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,08635896 0,11507856 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,08635896 0,11501193 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,08635896 0,11494537 ! peptide transport GO:0015833 43 25 0,000 0,08635896 0,11487889 ! male gonad development GO:0008584 33 25 0,000 0,08635896 0,11481248 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,08635896 0,11474616 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,08635896 0,11467991 ! phospholipid transport GO:0015914 35 25 0,000 0,08635896 0,11461373 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,08635896 0,11454763 ! detection of light stimulus GO:0009583 30 25 0,000 0,08635896 0,11448161 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,08635896 0,11441567 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,08635896 0,1143498 ! leukocyte proliferation GO:0070661 39 25 0,000 0,08635896 0,114284 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,08635896 0,11421828 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,08965616 0,11851102 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,08965616 0,11844295 ! translational initiation GO:0006413 43 26 0,000 0,08965616 0,11837496 ! regulation of pH GO:0006885 36 26 0,000 0,08965616 0,11830704 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,08965616 0,11823921 ! circadian rhythm GO:0007623 42 26 0,000 0,08965616 0,11817145 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,08965616 0,11810377 ! post-embryonic development GO:0009791 42 26 0,000 0,08965616 0,11803616 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,08965616 0,11796864 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,08965616 0,11790119 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,08965616 0,11783382 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,08965616 0,11776652 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,08965616 0,1176993 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,08965616 0,11763216 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,08965616 0,1175651 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,08965616 0,11749811 ! regulation of coagulation GO:0050818 39 26 0,000 0,08965616 0,1174312 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,09294166 0,12166524 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,09294166 0,12159603 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,09294166 0,1215269 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,09294166 0,12145786 ! membrane docking GO:0022406 39 27 0,000 0,09294166 0,12138888 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,09294166 0,12131999 ! catechol metabolic process GO:0009712 43 27 0,000 0,09294166 0,12125118 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,09294166 0,12118244 ! acute-phase response GO:0006953 42 27 0,000 0,09294166 0,12111378 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,09294166 0,1210452 ! myofibril assembly GO:0030239 36 27 0,000 0,09294166 0,1209767 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,09294166 0,12090827 ! response to ionizing radiation GO:0010212 47 27 0,000 0,09294166 0,12083992 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,09294166 0,12077165 ! natural killer cell activation GO:0030101 35 27 0,000 0,09294166 0,12070346 ! lipid oxidation GO:0034440 38 27 0,000 0,09294166 0,12063534 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,09294166 0,1205673 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,09294166 0,12049934 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,09294166 0,12043145 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,09294166 0,12036364 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,09294166 0,12029591 ! gene silencing GO:0016458 41 27 0,000 0,09294166 0,12022825 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,09621549 0,12439327 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,09621549 0,12432339 ! phenol metabolic process GO:0018958 44 28 0,000 0,09621549 0,12425358 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,09621549 0,12418386 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,09621549 0,12411421 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,09621549 0,12404464 ! cell junction assembly GO:0034329 56 28 0,000 0,09621549 0,12397514 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,09621549 0,12390573 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,09621549 0,12383639 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,09621549 0,12376713 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,09621549 0,12369795 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,09621549 0,12362884 ! response to organic cyclic substance GO:0014070 47 28 0,000 0,09621549 0,12355982 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,09621549 0,12349087 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,09621549 0,12342199 ! mesoderm formation GO:0001707 46 28 0,000 0,09621549 0,12335319 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,09621549 0,12328447 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,09621549 0,12321583 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,09621549 0,12314726 ! ensheathment of neurons GO:0007272 43 28 0,000 0,09621549 0,12307877 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,09621549 0,12301036 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,09621549 0,12294202 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,09621549 0,12287375 ! neural tube formation GO:0001841 41 28 0,000 0,09621549 0,12280557 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,09621549 0,12273745 ! regulation of B cell activation GO:0050864 42 28 0,000 0,09621549 0,12266942 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,09947769 0,12675828 ! regulation of innate immune response GO:0045088 38 29 0,000 0,09947769 0,12668809 ! ovulation cycle process GO:0022602 41 29 0,000 0,09947769 0,12661798 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,09947769 0,12654795 ! protein targeting to membrane GO:0006612 53 29 0,000 0,09947769 0,12647799 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,09947769 0,12640812 ! mismatch repair GO:0006298 34 29 0,000 0,09947769 0,12633832 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,09947769 0,12626859 ! muscle cell development GO:0055001 38 29 0,000 0,09947769 0,12619895 ! formation of primary germ layer GO:0001704 48 29 0,000 0,09947769 0,12612938 ! telencephalon development GO:0021537 52 29 0,000 0,09947769 0,12605988 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,09947769 0,12599047 ! eye morphogenesis GO:0048592 51 29 0,000 0,09947769 0,12592113 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,09947769 0,12585186 ! tissue homeostasis GO:0001894 42 29 0,000 0,09947769 0,12578268 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,1027283 0,12982148 ! collagen metabolic process GO:0032963 40 30 0,000 0,1027283 0,12975019 ! cholesterol transport GO:0030301 46 30 0,000 0,1027283 0,12967898 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,1027283 0,12960784 ! spliceosome assembly GO:0000245 49 30 0,000 0,1027283 0,12953678 ! spindle organization GO:0007051 37 30 0,000 0,1027283 0,1294658 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,1027283 0,1293949 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,1027283 0,12932408 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,1027283 0,12925333 ! ceramide metabolic process GO:0006672 43 30 0,000 0,1027283 0,12918266 ! ovulation cycle GO:0042698 43 30 0,000 0,1027283 0,12911207 ! hindbrain development GO:0030902 45 30 0,000 0,1027283 0,12904156 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,1027283 0,12897112 ! adult locomotory behavior GO:0008344 47 30 0,000 0,1027283 0,12890076 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,1027283 0,12883048 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,1027283 0,12876027 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,1027283 0,12869014 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,1027283 0,12862008 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,1027283 0,12855011 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,10596736 0,13253123 ! negative regulation of secretion GO:0051048 49 31 0,000 0,10596736 0,1324592 ! glial cell differentiation GO:0010001 55 31 0,000 0,10596736 0,13238726 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,10596736 0,13231538 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,10596736 0,13224359 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,10596736 0,13217187 ! odontogenesis GO:0042476 50 31 0,000 0,10596736 0,13210024 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,10596736 0,13202868 ! segmentation GO:0035282 41 31 0,000 0,10596736 0,13195719 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,10596736 0,13188579 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,10596736 0,13181446 ! metanephros development GO:0001656 58 31 0,000 0,10596736 0,13174321 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,10596736 0,13167204 ! cell fate specification GO:0001708 37 31 0,000 0,10596736 0,13160094 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,10596736 0,13152992 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,10596736 0,13145897 ! RNA modification GO:0009451 40 31 0,000 0,10596736 0,13138811 ! regulation of muscle development GO:0048634 48 32 0,000 0,10919492 0,13531698 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,10919492 0,13524411 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,10919492 0,13517132 ! meiosis I GO:0007127 52 32 0,000 0,10919492 0,13509861 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,10919492 0,13502597 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,10919492 0,13495342 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,10919492 0,13488094 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,10919492 0,13480854 ! peripheral nervous system development GO:0007422 53 32 0,000 0,10919492 0,13473622 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,10919492 0,13466397 ! cytokine production GO:0001816 44 32 0,000 0,10919492 0,13459181 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,10919492 0,13451972 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,10919492 0,1344477 ! vesicle localization GO:0051648 47 32 0,000 0,10919492 0,13437577 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,11241101 0,13825953 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,11241101 0,13818563 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,11241101 0,13811181 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,11241101 0,13803807 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,11241101 0,13796441 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,11241101 0,13789083 ! sister chromatid segregation GO:0000819 46 33 0,000 0,11241101 0,13781733 ! actomyosin structure organization GO:0031032 43 33 0,000 0,11241101 0,13774391 ! cell junction organization GO:0034330 63 33 0,000 0,11241101 0,13767056 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,11241101 0,13759729 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,11241101 0,1375241 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,11241101 0,13745099 GO:0042593|glucose homeostasis, ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,11241101 0,13737796 ! female gonad development GO:0008585 49 33 0,000 0,11241101 0,137305 ! positive regulation of cell development GO:0010720 54 33 0,000 0,11241101 0,13723212 ! lipid homeostasis GO:0055088 55 33 0,000 0,11241101 0,13715932 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,11241101 0,13708659 ! regulation of proteolysis GO:0030162 50 33 0,000 0,11241101 0,13701394 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,11241101 0,13694137 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,11241101 0,13686888 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,11241101 0,13679646 ! cytokinesis GO:0000910 52 33 0,000 0,11241101 0,13672412 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,11241101 0,13665186 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,11561567 0,14047334 ! mRNA catabolic process GO:0006402 48 34 0,000 0,11561567 0,14039917 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,11561567 0,14032508 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,11561567 0,14025107 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,11561567 0,14017714 ! feeding behavior GO:0007631 45 34 0,000 0,11561567 0,14010328 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,11561567 0,14002951 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,11561567 0,13995581 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,11561567 0,13988218 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,11561567 0,13980864 ! neuron migration GO:0001764 46 34 0,000 0,11561567 0,13973517 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,11561567 0,13966178 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,11561567 0,13958847 ! polyol metabolic process GO:0019751 44 34 0,000 0,11561567 0,13951523 ! aerobic respiration GO:0009060 47 34 0,000 0,11561567 0,13944207 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,11561567 0,13936899 ! embryonic organ development GO:0048568 45 34 0,000 0,11561567 0,13929598 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,11561567 0,13922305 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,11880894 0,14299349 ! Notch signaling pathway GO:0007219 56 35 0,000 0,11880894 0,1429187 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,11880894 0,14284399 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,11880894 0,14276936 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,11880894 0,14269481 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,11880894 0,14262033 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,11880894 0,14254593 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,11880894 0,14247161 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,11880894 0,14239737 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,11880894 0,14232321 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,11880894 0,14224912 ! glycogen metabolic process GO:0005977 48 35 0,000 0,11880894 0,14217511 ! pigment metabolic process GO:0042440 61 35 0,000 0,11880894 0,14210117 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,11880894 0,14202732 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,11880894 0,14195354 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,12199086 0,14567964 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,12199086 0,14560404 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,12199086 0,14552852 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,12199086 0,14545308 ! organic ether metabolic process GO:0018904 46 36 0,000 0,12199086 0,14537771 ! tissue remodeling GO:0048771 62 36 0,000 0,12199086 0,14530242 ! neural tube development GO:0021915 50 36 0,000 0,12199086 0,14522722 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,12199086 0,14515209 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,12199086 0,14507703 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,12199086 0,14500206 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,12199086 0,14492716 ! glucan metabolic process GO:0044042 49 36 0,000 0,12199086 0,14485234 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,12516148 0,14854045 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,12516148 0,14846385 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,12516148 0,14838732 ! learning GO:0007612 67 37 0,000 0,12516148 0,14831087 ! ion transmembrane transport GO:0034220 56 37 0,000 0,12516148 0,1482345 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,12516148 0,14815821 ! regulation of protein secretion GO:0050708 51 37 0,000 0,12516148 0,148082 ! amino acid activation GO:0043038 52 37 0,000 0,12516148 0,14800586 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,12516148 0,1479298 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,12832083 0,15158598 ! gliogenesis GO:0042063 71 38 0,000 0,12832083 0,15150816 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,12832083 0,15143043 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,12832083 0,15135277 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,12832083 0,15127519 ! phagocytosis GO:0006909 60 38 0,000 0,12832083 0,1511977 ! mesenchymal cell development GO:0014031 64 38 0,000 0,12832083 0,15112028 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of location in cell GO:0051651 69 38 0,000 0,12832083 0,15104294 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,13146895 0,15466935 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,13146895 0,15459027 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,13146895 0,15451128 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,13146895 0,15443237 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,13146895 0,15435353 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,13146895 0,15427478 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,13146895 0,15419611 ! male sex differentiation GO:0046661 53 39 0,000 0,13146895 0,15411752 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,13146895 0,15403901 ! chromatin remodeling GO:0006338 68 39 0,000 0,13146895 0,15396058 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,13146895 0,15388223 ! JNK cascade GO:0007254 54 39 0,000 0,13146895 0,15380395 ! developmental growth GO:0048589 62 39 0,000 0,13146895 0,15372576 ! cell growth GO:0016049 61 39 0,000 0,13146895 0,15364765 ! synapse organization GO:0050808 55 39 0,000 0,13146895 0,15356962 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,13460587 0,15715407 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,13460587 0,15707433 ! regulation of tube size GO:0035150 60 40 0,000 0,13460587 0,15699468 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,13460587 0,15691511 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,13460587 0,15683562 ! peptide metabolic process GO:0006518 56 40 0,000 0,13460587 0,15675621 ! inner ear development GO:0048839 57 40 0,000 0,13460587 0,15667688 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,13460587 0,15659763 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,13460587 0,15651846 ! double-strand break repair GO:0006302 67 40 0,000 0,13460587 0,15643937 ! B cell differentiation GO:0030183 62 40 0,000 0,13460587 0,15636036 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,13460587 0,15628143 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,13460587 0,15620258 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,13460587 0,15612381 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,13460587 0,15604512 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,13773165 0,15958831 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,13773165 0,15950796 ! glucose transport GO:0015758 52 41 0,000 0,13773165 0,15942768 ! endosome transport GO:0016197 71 41 0,000 0,13773165 0,15934749 ! striated muscle contraction GO:0006941 62 41 0,000 0,13773165 0,15926737 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,13773165 0,15918734 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,13773165 0,15910738 ! biopolymer methylation GO:0043414 62 41 0,000 0,13773165 0,15902751 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,13773165 0,15894772 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,14084632 0,16246065 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,14084632 0,16237922 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,14084632 0,16229786 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,14084632 0,16221659 ! hexose transport GO:0008645 54 42 0,000 0,14084632 0,1621354 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,14084632 0,1620543 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,14084632 0,16197327 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,14084632 0,16189232 ! excretion GO:0007588 63 42 0,000 0,14084632 0,16181146 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,14084632 0,16173067 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,14084632 0,16164997 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,14084632 0,16156934 ! regulation of cell shape GO:0008360 78 42 0,000 0,14084632 0,1614888 ! positive regulation of binding GO:0051099 59 43 0,000 0,14394991 0,16496502 ! leukocyte migration GO:0050900 60 43 0,000 0,14394991 0,16488287 ! neuromuscular process GO:0050905 79 43 0,000 0,14394991 0,1648008 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,14394991 0,16471881 ! tRNA processing GO:0008033 49 43 0,000 0,14394991 0,1646369 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,14394991 0,16455507 ! methylation GO:0032259 64 43 0,000 0,14394991 0,16447332 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,14704247 0,16792338 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,14704247 0,16784005 ! glycolysis GO:0006096 53 44 0,000 0,14704247 0,16775679 ! regulation of action potential GO:0001508 71 44 0,000 0,14704247 0,16767362 ! regulation of ion transport GO:0043269 57 44 0,000 0,14704247 0,16759053 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,14704247 0,16750752 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,14704247 0,1674246 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,14704247 0,16734176 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,14704247 0,167259 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,14704247 0,16717632 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,14704247 0,16709372 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,14704247 0,16701121 ! RNA catabolic process GO:0006401 64 45 0,000 0,15012404 0,17042709 ! positive regulation of defense response GO:0031349 59 45 0,000 0,15012404 0,17034301 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,15012404 0,17025902 ! cell recognition GO:0008037 58 45 0,000 0,15012404 0,17017511 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,15012404 0,17009128 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,15319465 0,17348483 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,15319465 0,17339945 ! cell redox homeostasis GO:0045454 63 46 0,000 0,15319465 0,17331416 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,15319465 0,17322895 ! regulation of ossification GO:0030278 71 46 0,000 0,15319465 0,17314383 ! histone modification GO:0016570 68 46 0,000 0,15319465 0,17305879 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,15625434 0,17642856 ! viral infectious cycle GO:0019058 71 47 0,000 0,15625434 0,17634199 ! covalent chromatin modification GO:0016569 75 47 0,000 0,15625434 0,1762555 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,15625434 0,1761691 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,15625434 0,17608279 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,15625434 0,17599656 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,15625434 0,17591041 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,15625434 0,17582435 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of protein polymerization GO:0032271 71 47 0,000 0,15625434 0,17573837 ! chloride transport GO:0006821 67 48 0,000 0,15930314 0,17907978 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,15930314 0,1789923 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,15930314 0,1789049 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,15930314 0,17881759 ! gastrulation GO:0007369 73 48 0,000 0,15930314 0,17873036 ! heart morphogenesis GO:0003007 65 48 0,000 0,15930314 0,17864321 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,15930314 0,17855616 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,15930314 0,17846918 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,15930314 0,17838229 ! nuclear export GO:0051168 69 48 0,000 0,15930314 0,17829549 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,16234111 0,18160727 ! sensory perception of smell GO:0007608 61 49 0,000 0,16234111 0,18151899 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,16234111 0,18143078 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,16234111 0,18134267 ! RNA elongation GO:0006354 62 49 0,000 0,16234111 0,18125464 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,16234111 0,18116669 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,16234111 0,18107883 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,16234111 0,18099106 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,16234111 0,18090337 ! maintenance of location GO:0051235 84 49 0,000 0,16234111 0,18081576 ! regulation of actin filament length GO:0030832 72 50 0,000 0,16536827 0,18409827 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,16536827 0,1840092 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,16536827 0,18392023 ! lipid modification GO:0030258 73 50 0,000 0,16536827 0,18383133 ! positive regulation of growth GO:0045927 67 50 0,000 0,16536827 0,18374252 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,16536827 0,1836538 ! proton transport GO:0015992 75 50 0,000 0,16536827 0,18356517 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,16536827 0,18347662 ! positive regulation of secretion GO:0051047 71 51 0,000 0,16838467 0,18673324 ! hydrogen transport GO:0006818 77 51 0,000 0,16838467 0,18664325 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,16838467 0,18655334 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,16838467 0,18646352 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,16838467 0,18637379 ! adult behavior GO:0030534 80 51 0,000 0,16838467 0,18628414 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,16838467 0,18619458 ! regulation of cellular component size GO:0032535 74 52 0,000 0,17139033 0,18942709 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,17139033 0,1893361 ! aging GO:0007568 79 52 0,000 0,17139033 0,18924521 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,17139033 0,1891544 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,17139033 0,18906368 ! establishment of organelle localization GO:0051656 85 52 0,000 0,17139033 0,18897304 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,17438531 0,19218314 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,17438531 0,1920911 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,17438531 0,19199914 ! kidney development GO:0001822 90 53 0,000 0,17438531 0,19190728 ! single fertilization GO:0007338 59 53 0,000 0,17438531 0,1918155 ! amino acid transport GO:0006865 84 54 0,000 0,17736963 0,19500485 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,17736963 0,19491168 ! regulation of mitosis GO:0007088 84 54 0,000 0,17736963 0,1948186 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,17736963 0,19472561 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,17736963 0,1946327 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,17736963 0,19453989 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,17736963 0,19444716 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,17736963 0,19435452 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,17736963 0,19426197 ! exocytosis GO:0006887 74 55 0,000 0,18034333 0,19742488 ! mesoderm development GO:0007498 76 55 0,000 0,18034333 0,19733095 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,18034333 0,19723712 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,18034333 0,19714338 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,18330646 0,20028734 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,18330646 0,20019224 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,18625904 0,20332026 ! carbohydrate transport GO:0008643 74 57 0,000 0,18625904 0,20322381 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,18625904 0,20312745 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,18625904 0,20303118 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,18625904 0,202935 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,18625904 0,20283892 ! camera-type eye development GO:0043010 88 57 0,000 0,18625904 0,20274292 ! secondary metabolic process GO:0019748 84 57 0,000 0,18625904 0,20264702 ! gonad development GO:0008406 79 57 0,000 0,18625904 0,2025512 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,18920112 0,20565339 ! viral reproductive process GO:0022415 87 58 0,000 0,18920112 0,20555624 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,18920112 0,20545919 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,18920112 0,20536223 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,19213272 0,20844588 ! activation of MAPK activity GO:0000187 84 59 0,000 0,19213272 0,2083476 ! lung development GO:0030324 94 59 0,000 0,19213272 0,20824942 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,19213272 0,20815133 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,19213272 0,20805333 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,1950539 0,21111716 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,1950539 0,21101786 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,1950539 0,21091865 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,1950539 0,21081953 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,1950539 0,21072051 ! fertilization GO:0009566 68 60 0,000 0,1950539 0,21062158 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,19796468 0,21366436 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,19796468 0,21356415 ! urogenital system development GO:0001655 101 61 0,000 0,19796468 0,21346402 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,19796468 0,21336399 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,19796468 0,21326406 ! extracellular matrix organization GO:0030198 103 61 0,000 0,19796468 0,21316421 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,19796468 0,21306446 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,19796468 0,21296481 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,19796468 0,21286525 ! amine catabolic process GO:0009310 90 62 0,000 0,2008651 0,21588305 ! neurotransmitter transport GO:0006836 81 62 0,000 0,2008651 0,21578222 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,2008651 0,21568148 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,2008651 0,21558083 ! respiratory tube development GO:0030323 99 62 0,000 0,2008651 0,21548028 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,2008651 0,21537983 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,2008651 0,21527946 ! organelle localization GO:0051640 96 62 0,000 0,2008651 0,21517919 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,2037552 0,21817363 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,2037552 0,2180721 ! viral reproduction GO:0016032 92 63 0,000 0,2037552 0,21797067 ! regulation of lipase activity GO:0060191 109 63 0,000 0,2037552 0,21786934 ! negative regulation of cell size GO:0045792 108 64 0,000 0,20663501 0,22084596 ! appendage morphogenesis GO:0035107 93 64 0,000 0,20663501 0,22074339 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,20663501 0,22064091 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,20663501 0,22053852 ! hexose catabolic process GO:0019320 82 64 0,000 0,20663501 0,22043623 ! respiratory system development GO:0060541 100 64 0,000 0,20663501 0,22033404 ! adaptive immune response GO:0002250 94 64 0,000 0,20663501 0,22023194 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,20950457 0,22318689 ! appendage development GO:0048736 94 65 0,000 0,20950457 0,22308357 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,20950457 0,22298033 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,20950457 0,2228772 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,20950457 0,22277416 ! defense response to bacterium GO:0042742 73 65 0,000 0,20950457 0,22267121 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,20950457 0,22256836 ! protein oligomerization GO:0051259 100 65 0,000 0,20950457 0,22246561 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,21236391 0,22539778 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,21236391 0,22529382 ! antigen processing and presentation GO:0019882 96 66 0,000 0,21236391 0,22518995 ! axon guidance GO:0007411 99 66 0,000 0,21236391 0,22508617 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,21236391 0,2249825 ! regulation of immune effector process GO:0002697 101 66 0,000 0,21236391 0,22487891 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,21521308 0,22779111 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,21521308 0,22768633 ! acute inflammatory response GO:0002526 92 68 0,000 0,2180521 0,23058383 ! learning or memory GO:0007611 123 68 0,000 0,2180521 0,23047786 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,2180521 0,23037199 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,2180521 0,23026622 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,2180521 0,23016055 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,2180521 0,23005497 ! rhythmic process GO:0048511 105 68 0,000 0,2180521 0,22994949 ! inorganic anion transport GO:0015698 93 68 0,000 0,2180521 0,2298441 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,22088101 0,23271935 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,22088101 0,23261279 ! response to drug GO:0042493 108 69 0,000 0,22088101 0,23250633 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,22088101 0,23239997 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,22369986 0,23525819 ! humoral immune response GO:0006959 86 70 0,000 0,22369986 0,23515067 ! eye development GO:0001654 111 70 0,000 0,22369986 0,23504325 ! amine transport GO:0015837 101 70 0,000 0,22369986 0,23493592 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,22650866 0,23777723 ! muscle cell differentiation GO:0042692 104 71 0,000 0,22650866 0,23766876 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,22650866 0,23756038 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,22650866 0,23745211 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,22650866 0,23734393 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,22650866 0,23723585 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,22650866 0,23712787 ! response to hypoxia GO:0001666 132 72 0,000 0,22930746 0,23994867 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,22930746 0,23983955 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,22930746 0,23973053 ! negative regulation of transport GO:0051051 116 73 0,000 0,2320963 0,24253589 ! regulation of blood pressure GO:0008217 107 73 0,000 0,2320963 0,24242574 ! tube morphogenesis GO:0035239 118 73 0,000 0,2320963 0,2423157 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,2320963 0,24220576 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,2348752 0,24499454 ! response to oxygen levels GO:0070482 137 74 0,000 0,2348752 0,24488349 ! digestion GO:0007586 97 74 0,000 0,2348752 0,24477253 ! protein import into nucleus GO:0006606 118 74 0,000 0,2348752 0,24466167 ! blood coagulation GO:0007596 116 75 0,000 0,23764421 0,24743399 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,23764421 0,24732203 ! regulation of ligase activity GO:0051340 114 75 0,000 0,23764421 0,24721017 ! nuclear import GO:0051170 121 75 0,000 0,23764421 0,24709841 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,23764421 0,24698675 ! amine biosynthetic process GO:0009309 97 76 0,000 0,24040335 0,24974151 ! tRNA metabolic process GO:0006399 95 76 0,000 0,24040335 0,24962876 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,24040335 0,24951612 ! regulation of protein transport GO:0051223 114 76 0,000 0,24040335 0,24940357 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,24315267 0,25214208 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,24315267 0,25202845 ! sex differentiation GO:0007548 105 77 0,000 0,24315267 0,25191493 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,24315267 0,2518015 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,24315267 0,25168818 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,24315267 0,25157496 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,24589219 0,25429498 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,24589219 0,25418069 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,24862195 0,25688701 ! cellular respiration GO:0045333 107 79 0,000 0,24862195 0,25677166 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,24862195 0,25665642 ! T cell activation GO:0042110 134 79 0,000 0,24862195 0,25654127 ! regulation of lyase activity GO:0051339 133 79 0,000 0,24862195 0,25642623 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,24862195 0,25631129 ! chromatin assembly GO:0031497 102 80 0,000 0,25134199 0,25899936 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,25134199 0,25888338 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,25134199 0,25876749 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,25134199 0,25865171 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,25134199 0,25853604 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,25405234 0,26120714 ! hemostasis GO:0007599 125 81 0,000 0,25405234 0,26109043 ! mRNA transport GO:0051028 121 81 0,000 0,25405234 0,26097382 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,25405234 0,26085731 ! regulation of neurological system process GO:0031644 122 81 0,000 0,25405234 0,26074091 ! vitamin metabolic process GO:0006766 103 81 0,000 0,25405234 0,26062461 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,2594441 0,26603719 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,2594441 0,26591864 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,2594441 0,26580019 ! regulation of defense response GO:0031347 117 84 0,000 0,26212557 0,26842779 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,26212557 0,26830833 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,26212557 0,26818898 ! sterol metabolic process GO:0016125 120 84 0,000 0,26212557 0,26806973 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,26479749 0,27068188 ! rRNA metabolic process GO:0016072 107 85 0,000 0,26479749 0,27056163 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,26479749 0,27044149 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,26479749 0,27032145 ! regulation of protein localization GO:0032880 132 85 0,000 0,26479749 0,27020152 ! regulation of membrane potential GO:0042391 128 85 0,000 0,26479749 0,2700817 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,26745989 0,27267631 ! nucleosome organization GO:0034728 114 87 0,000 0,2701128 0,27525895 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,2701128 0,27513704 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,2701128 0,27501525 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,2701128 0,27489356 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,2701128 0,27477198 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,2701128 0,27465051 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,27275626 0,27721582 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,27275626 0,27709337 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,27275626 0,27697103 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,27275626 0,27684881 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! regulation of neurogenesis GO:0050767 153 89 0,000 0,27539029 0,27939906 ! reproductive developmental process GO:0003006 127 89 0,000 0,27539029 0,27927587 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,27539029 0,27915278 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,27539029 0,27902981 ! leukocyte differentiation GO:0002521 143 90 0,000 0,27801493 0,2815651 ! hormone metabolic process GO:0042445 121 90 0,000 0,27801493 0,28144117 ! RNA localization GO:0006403 135 91 0,000 0,28063022 0,28396371 ! ATP metabolic process GO:0046034 137 91 0,000 0,28063022 0,28383883 ! response to virus GO:0009615 122 91 0,000 0,28063022 0,28371407 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,28323618 0,28622285 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,28323618 0,28609715 ! DNA recombination GO:0006310 146 92 0,000 0,28323618 0,28597156 ! sulfur metabolic process GO:0006790 118 92 0,000 0,28323618 0,28584608 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,28583285 0,28834016 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,28583285 0,28821375 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,28583285 0,28808745 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,28583285 0,28796126 ! electron transport chain GO:0022900 123 94 0,000 0,28842027 0,29044072 ! response to oxidative stress GO:0006979 141 94 0,000 0,28842027 0,29031362 ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,29356745 0,29536532 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,29356745 0,29523617 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,29356745 0,29510714 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,29612728 0,29755035 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,29612728 0,29742041 ! calcium ion transport GO:0006816 167 99 0,000 0,30121959 0,30240291 ! extracellular structure organization GO:0043062 156 99 0,000 0,30121959 0,30227097 ! protein import GO:0017038 156 99 0,000 0,30121959 0,30213914 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,30121959 0,30200744 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,30375213 0,3044139 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,30375213 0,30428132 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,30375213 0,30414885 ! divalent metal ion transport GO:0070838 171 100 0,000 0,30375213 0,30401649 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,30375213 0,30388426 ! protein localization in organelle GO:0033365 161 100 0,000 0,30375213 0,30375213