pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-pos-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/103-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of translation GO:0006417 151 100 6,000 3,354E-07 7,714E-04 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 2,000 8,824E-07 1,015E-03 ! respiratory burst GO:0045730 14 11 2,000 1,428E-05 0,01094618 ! negative regulation of translation GO:0017148 22 16 2,000 4,767E-05 0,02741241 ! immunoglobulin mediated immune response GO:0016064 66 48 3,000 6,462E-05 0,02972305 GO:0019724|B cell mediated immunity, ! peptide cross-linking GO:0018149 31 18 2,000 6,902E-05 0,02645621 ! estrogen receptor signaling pathway GO:0030520 30 18 2,000 6,902E-05 0,02267675 ! lymphocyte mediated immunity GO:0002449 88 62 3,000 1,766E-04 0,05076746 ! adaptive immune response GO:0002250 94 64 3,000 1,998E-04 0,05104824 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 1,999E-04 0,04596863 ! nucleoside salvage GO:0043174 7 5 1,000 1,999E-04 0,04178967 GO:0006166|purine ribonucleoside salvage, ! determination of adult lifespan GO:0008340 8 5 1,000 1,999E-04 0,03830719 ! translational initiation GO:0006413 43 26 2,000 2,143E-04 0,03790589 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 2,000 2,143E-04 0,03519833 ! acute inflammatory response GO:0002526 92 68 3,000 2,526E-04 0,03872523 ! complement activation, classical pathway GO:0006958 36 28 2,000 2,682E-04 0,03855451 ! leukocyte mediated immunity GO:0002443 99 71 3,000 2,982E-04 0,04035141 ! regulation of helicase activity GO:0051095 11 6 1,000 2,989E-04 0,03819481 ! regulation of dopamine metabolic process GO:0042053 9 6 1,000 2,989E-04 0,03618456 GO:0042069|regulation of catecholamine metabolic process, ! purine salvage GO:0043101 8 6 1,000 2,989E-04 0,03437533 ! negative regulation of DNA recombination GO:0045910 9 6 1,000 2,989E-04 0,03273841 ! negative regulation of translational initiation GO:0045947 7 6 1,000 2,989E-04 0,0312503 ! regulation of collagen metabolic process GO:0010712 7 6 1,000 2,989E-04 0,02989159 ! wound healing, spreading of epidermal cells GO:0035313 10 6 1,000 2,989E-04 0,02864611 ! interaction with symbiont GO:0051702 8 6 1,000 2,989E-04 0,02750026 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 2,000 3,302E-04 0,02921322 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 1,000 4,173E-04 0,03554394 GO:0016446|somatic hypermutation of immunoglobulin genes, ! negative regulation of cellular catabolic process GO:0031330 9 7 1,000 4,173E-04 0,03427451 ! regulation of cellular amine metabolic process GO:0033238 10 7 1,000 4,173E-04 0,03309263 ! regulation of smooth muscle cell migration GO:0014910 19 7 1,000 4,173E-04 0,03198954 ! fibril organization GO:0043206 13 7 1,000 4,173E-04 0,03095762 ! response to UV-B GO:0010224 11 7 1,000 4,173E-04 0,0299902 ! multicellular organismal aging GO:0010259 11 7 1,000 4,173E-04 0,0290814 ! protein homooligomerization GO:0051260 52 35 2,000 5,238E-04 0,03543242 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 1,000 5,547E-04 0,03645229 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 1,000 5,547E-04 0,03543972 ! lamellipodium assembly GO:0030032 9 8 1,000 5,547E-04 0,03448189 ! mitochondrion localization GO:0051646 12 8 1,000 5,547E-04 0,03357448 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 2,000 6,178E-04 0,03643389 GO:0006956|complement activation, ! positive regulation of phagocytosis GO:0050766 11 9 1,000 7,111E-04 0,04088863 ! cellular metabolic compound salvage GO:0043094 11 9 1,000 7,111E-04 0,03989135 ! purine base metabolic process GO:0006144 18 9 1,000 7,111E-04 0,03894155 ! detection of calcium ion GO:0005513 13 9 1,000 7,111E-04 0,03803593 ! embryonic placenta development GO:0001892 12 9 1,000 7,111E-04 0,03717148 ! positive regulation of protein polymerization GO:0032273 15 9 1,000 7,111E-04 0,03634545 ! protein homotetramerization GO:0051289 18 11 1,000 1,08E-03 0,05400284 ! regulation of phagocytosis GO:0050764 14 11 1,000 1,08E-03 0,05285385 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 1,000 1,08E-03 0,05175273 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! regulation of translational initiation GO:0006446 64 45 2,000 1,099E-03 0,05160145 ! response to UV GO:0009411 75 46 2,000 1,172E-03 0,05392242 ! immunoglobulin production during immune response GO:0002381 20 12 1,000 1,292E-03 0,05827899 ! positive regulation of protein complex assembly GO:0031334 19 13 1,000 1,523E-03 0,06735292 ! regulation of exocytosis GO:0017157 17 13 1,000 1,523E-03 0,06608211 ! heterophilic cell adhesion GO:0007157 29 14 1,000 1,771E-03 0,07544668 ! pituitary gland development GO:0021983 23 14 1,000 1,771E-03 0,07407492 ! cellular response to starvation GO:0009267 21 14 1,000 1,771E-03 0,07275216 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 1,771E-03 0,0714758 ! cell killing GO:0001906 20 14 1,000 1,771E-03 0,07024346 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 2,038E-03 0,07944335 ! defense response to virus GO:0051607 27 15 1,000 2,038E-03 0,0781193 ! steroid hormone receptor signaling pathway GO:0030518 96 58 2,000 2,292E-03 0,08641738 ! protein maturation by peptide bond cleavage GO:0051605 76 58 2,000 2,292E-03 0,08502355 ! diencephalon development GO:0021536 25 16 1,000 2,322E-03 0,08477917 ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 1,000 2,322E-03 0,08345449 ! regulation of vesicle-mediated transport GO:0060627 79 60 2,000 2,525E-03 0,08936118 ! signal complex assembly GO:0007172 29 17 1,000 2,624E-03 0,09144754 ! memory GO:0007613 25 17 1,000 2,624E-03 0,09008265 ! keratinization GO:0031424 17 17 1,000 2,624E-03 0,0887579 ! negative regulation of peptidase activity GO:0010466 23 17 1,000 2,624E-03 0,08747156 ! cell-substrate junction assembly GO:0007044 39 17 1,000 2,624E-03 0,08622196 ! nucleobase metabolic process GO:0009112 31 17 1,000 2,624E-03 0,08500757 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 2,000 2,902E-03 0,09271477 ! positive regulation of angiogenesis GO:0045766 35 18 1,000 2,944E-03 0,09274161 ! positive regulation of cytoskeleton organization GO:0051495 33 18 1,000 2,944E-03 0,09148834 ! detection of chemical stimulus GO:0009593 26 18 1,000 2,944E-03 0,0902685 ! cellular response to nutrient levels GO:0031669 27 18 1,000 2,944E-03 0,08908076 ! activation of immune response GO:0002253 83 65 2,000 3,172E-03 0,09474494 ! protein oligomerization GO:0051259 100 65 2,000 3,172E-03 0,09353026 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 1,000 3,28E-03 0,09550025 ! response to starvation GO:0042594 30 19 1,000 3,28E-03 0,0943065 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 1,000 3,28E-03 0,09314222 ! somatic diversification of immunoglobulins GO:0016445 29 19 1,000 3,28E-03 0,09200634 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 2,000 3,456E-03 0,09577705 ! cytosolic calcium ion homeostasis GO:0051480 107 68 2,000 3,604E-03 0,09868554 ! humoral immune response GO:0006959 86 70 2,000 3,911E-03 0,10583723 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 1,000 4,005E-03 0,10710666 GO:0016444|somatic cell DNA recombination, ! gluconeogenesis GO:0006094 25 21 1,000 4,005E-03 0,10587555 ! regulation of DNA recombination GO:0000018 40 21 1,000 4,005E-03 0,10467242 ! purine ribonucleoside metabolic process GO:0046128 28 21 1,000 4,005E-03 0,10349632 GO:0042278|purine nucleoside metabolic process, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 4,005E-03 0,10234636 ! immunoglobulin production GO:0002377 33 21 1,000 4,005E-03 0,10122168 GO:0002440|production of molecular mediator of immune response, ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 4,005E-03 0,10012144 ! leukocyte adhesion GO:0007159 38 22 1,000 4,392E-03 0,1086314 ! protein tetramerization GO:0051262 39 22 1,000 4,392E-03 0,10747574 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 4,797E-03 0,11613266 ! interaction with host GO:0051701 37 23 1,000 4,797E-03 0,11492295 ! cell fate determination GO:0001709 45 23 1,000 4,797E-03 0,11373817 ! somatic diversification of immune receptors GO:0002200 35 23 1,000 4,797E-03 0,11257758 ! negative regulation of catabolic process GO:0009895 34 23 1,000 4,797E-03 0,11144043 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 5,218E-03 0,12000466 ! pyruvate metabolic process GO:0006090 29 24 1,000 5,218E-03 0,11881649 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 5,218E-03 0,11765162 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 1,000 5,218E-03 0,11650938 ! neurotransmitter secretion GO:0007269 32 24 1,000 5,218E-03 0,11538909 ! acute-phase response GO:0006953 42 27 1,000 6,578E-03 0,14408011 ! cell junction assembly GO:0034329 56 28 1,000 7,063E-03 0,15325173 ! positive regulation of endocytosis GO:0045807 33 28 1,000 7,063E-03 0,15181947 ! placenta development GO:0001890 37 28 1,000 7,063E-03 0,15041374 ! protein processing GO:0016485 114 88 2,000 7,399E-03 0,15613083 ! positive regulation of T cell proliferation GO:0042102 44 29 1,000 7,564E-03 0,1581563 ! mismatch repair GO:0006298 34 29 1,000 7,564E-03 0,15673146 ! hexose biosynthetic process GO:0019319 35 29 1,000 7,564E-03 0,15533208 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 1,000 8,081E-03 0,1644743 ! positive regulation of immune response GO:0050778 121 92 2,000 8,359E-03 0,16865392 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 8,613E-03 0,172257 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 9,16E-03 0,181627 ! meiosis I GO:0007127 52 32 1,000 9,16E-03 0,18007463 ! monosaccharide biosynthetic process GO:0046364 38 32 1,000 9,16E-03 0,17854857 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 9,16E-03 0,17704816 ! protein maturation GO:0051604 129 96 2,000 9,39E-03 0,17996587 ! response to light stimulus GO:0009416 153 96 2,000 9,39E-03 0,17847855 ! cell junction organization GO:0034330 63 33 1,000 9,723E-03 0,18330157 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 9,723E-03 0,18181131 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 0,01020871 0,18935519 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 0,01030061 0,18953122 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 0,01030061 0,188027 ! keratinocyte differentiation GO:0030216 47 35 1,000 0,01089314 0,19727742 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,01089314 0,19573619 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,01150041 0,20504616 GO:0090047|positive regulation of transcription regulator activity, ! ribonucleoside metabolic process GO:0009119 48 37 1,000 0,01212228 0,21447109 ! alcohol biosynthetic process GO:0046165 45 38 1,000 0,0127586 0,22400589 ! regulation of T cell proliferation GO:0042129 58 38 1,000 0,0127586 0,22230887 ! maintenance of location in cell GO:0051651 69 38 1,000 0,0127586 0,22063738 ! cell growth GO:0016049 61 39 1,000 0,01340923 0,23015836 ! regulation of actin filament polymerization GO:0030833 59 40 1,000 0,01407403 0,23977978 ! response to calcium ion GO:0051592 58 40 1,000 0,01407403 0,23801669 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 0,01407403 0,23627934 ! epidermal cell differentiation GO:0009913 53 40 1,000 0,01407403 0,23456718 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 0,01407403 0,23287964 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,01475287 0,24236859 ! regulation of cell shape GO:0008360 78 42 1,000 0,01544561 0,25194967 ! positive regulation of binding GO:0051099 59 43 1,000 0,01615211 0,26161873 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,01615211 0,25978923 ! response to insulin stimulus GO:0032868 63 43 1,000 0,01615211 0,25798514 ! negative regulation of cell migration GO:0030336 92 44 1,000 0,01687224 0,26762868 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 1,000 0,01687224 0,26579561 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 0,01687224 0,26398748 ! cell maturation GO:0048469 60 45 1,000 0,01760587 0,27360469 ! histone modification GO:0016570 68 46 1,000 0,01835285 0,28329903 ! endocrine system development GO:0035270 83 47 1,000 0,01911306 0,29306694 ! covalent chromatin modification GO:0016569 75 47 1,000 0,01911306 0,2911261 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 0,01911306 0,2892108 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of protein polymerization GO:0032271 71 47 1,000 0,01911306 0,28732053 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 1,000 0,01988637 0,29700421 ! regulation of endocytosis GO:0030100 63 48 1,000 0,01988637 0,29508805 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,02067264 0,30478894 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 0,02067264 0,30284761 ! maintenance of location GO:0051235 84 49 1,000 0,02067264 0,30093085 ! regulation of actin filament length GO:0030832 72 50 1,000 0,02147175 0,31059763 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,02228356 0,32032622 ! negative regulation of cell motion GO:0051271 104 51 1,000 0,02228356 0,31833662 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02239392 0,31793838 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,02239392 0,31598784 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02239392 0,31406108 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02239392 0,31215768 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02239392 0,31027722 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02239392 0,30841927 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02239392 0,30658344 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,02239392 0,30476934 ! sleep GO:0030431 11 5 0,000 0,02239392 0,30297658 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02239392 0,30120478 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02239392 0,29945359 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02239392 0,29772265 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,02239392 0,2960116 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,02239392 0,2943201 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,02239392 0,29264783 ! tongue development GO:0043586 6 5 0,000 0,02239392 0,29099445 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02239392 0,28935965 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02239392 0,28774312 ! cobalt ion transport GO:0006824 9 5 0,000 0,02239392 0,28614454 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02239392 0,28456363 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,02239392 0,2830001 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02239392 0,28145365 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02239392 0,27992401 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02239392 0,27841091 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02239392 0,27691407 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,02239392 0,27543325 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02239392 0,27396818 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02239392 0,27251861 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02239392 0,2710843 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02239392 0,26966502 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02239392 0,26826051 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,02239392 0,26687056 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02239392 0,26549494 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02239392 0,26413343 ! malate metabolic process GO:0006108 7 5 0,000 0,02239392 0,26278581 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02239392 0,26145187 ! behavioral response to pain GO:0048266 7 5 0,000 0,02239392 0,2601314 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02239392 0,25882421 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02239392 0,25753009 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02239392 0,25624885 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02239392 0,25498029 ! mating behavior GO:0007617 6 5 0,000 0,02239392 0,25372423 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02239392 0,25248048 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02239392 0,25124887 ! rhythmic behavior GO:0007622 12 5 0,000 0,02239392 0,25002921 ! copulation GO:0007620 7 5 0,000 0,02239392 0,24882134 ! glial cell fate commitment GO:0021781 12 5 0,000 0,02239392 0,24762509 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,02239392 0,24644028 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,02239392 0,24526675 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02239392 0,24410435 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,02239392 0,24295291 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02239392 0,24181229 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02239392 0,24068233 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02239392 0,23956287 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02239392 0,23845379 ! response to protozoan GO:0001562 9 5 0,000 0,02239392 0,23735492 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,02239392 0,23626614 ! lymph vessel development GO:0001945 7 5 0,000 0,02239392 0,2351873 ! endochondral ossification GO:0001958 12 5 0,000 0,02239392 0,23411826 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02239392 0,2330589 ! parathyroid gland development GO:0060017 8 5 0,000 0,02239392 0,23200909 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02239392 0,23096869 ! anagen GO:0042640 6 5 0,000 0,02239392 0,22993758 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02239392 0,22891564 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,02239392 0,22790273 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02239392 0,22689876 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,02239392 0,22590359 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02239392 0,22491711 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02239392 0,22393921 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02239392 0,22296977 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02239392 0,2220087 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02239392 0,22105587 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,02239392 0,22011119 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02239392 0,21917454 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02239392 0,21824584 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,02239392 0,21732497 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,02239392 0,21641184 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,02239392 0,21550635 ! ovulation GO:0030728 6 5 0,000 0,02239392 0,21460841 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,02239392 0,21371792 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,02239392 0,21283478 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,02239392 0,21195892 ! response to pH GO:0009268 9 5 0,000 0,02239392 0,21109024 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02239392 0,21022864 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02239392 0,20937406 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02239392 0,20852639 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02239392 0,20768556 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02239392 0,20685148 ! polyol catabolic process GO:0046174 7 5 0,000 0,02239392 0,20602407 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02239392 0,20520326 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02239392 0,20438896 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02239392 0,2035811 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,02239392 0,2027796 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02239392 0,20198438 ! urea metabolic process GO:0019627 6 5 0,000 0,02239392 0,20119538 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02239392 0,20041252 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02239392 0,19963573 ! neutrophil activation GO:0042119 5 5 0,000 0,02239392 0,19886493 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02239392 0,19810007 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02239392 0,19734106 ! response to food GO:0032094 5 5 0,000 0,02239392 0,19658785 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02239392 0,19584037 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02239392 0,19509855 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,02239392 0,19436233 ! forebrain neuron development GO:0021884 7 5 0,000 0,02239392 0,19363165 ! melanosome organization GO:0032438 7 5 0,000 0,02239392 0,19290643 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02239392 0,19218663 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02239392 0,19147219 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02239392 0,19076303 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02239392 0,19005911 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,02239392 0,18936036 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02239392 0,18866673 ! nucleoside transport GO:0015858 6 5 0,000 0,02239392 0,18797817 ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,02239392 0,18729461 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02239392 0,18661601 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02239392 0,1859423 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02239392 0,18527345 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02239392 0,18460938 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,02239392 0,18395006 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02239392 0,18329544 ! depyrimidination GO:0045008 8 5 0,000 0,02239392 0,18264545 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,02239392 0,18200006 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02239392 0,18135922 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02239392 0,18072287 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02239392 0,18009097 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02239392 0,17946348 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02239392 0,17884034 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,02239392 0,17822152 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,02239392 0,17760696 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02239392 0,17699663 ! monocyte differentiation GO:0030224 8 5 0,000 0,02239392 0,17639047 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,02239392 0,17578846 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02239392 0,17519054 ! centrosome duplication GO:0051298 5 5 0,000 0,02239392 0,17459667 ! response to UV-C GO:0010225 6 5 0,000 0,02239392 0,17400682 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02239392 0,17342094 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02239392 0,17283899 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02239392 0,17226093 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02239392 0,17168673 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02239392 0,17111634 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02239392 0,17054973 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,02239392 0,16998686 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,02239392 0,16942769 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,02239392 0,16887219 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02239392 0,16832032 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02239392 0,16777205 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,02239392 0,16722733 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02239392 0,16668614 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02239392 0,16614844 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02239392 0,16561421 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02239392 0,16508339 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02239392 0,16455597 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,02239392 0,1640319 ! neural tube patterning GO:0021532 6 5 0,000 0,02239392 0,16351117 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02239392 0,16299373 ! histone demethylation GO:0016577 9 5 0,000 0,02239392 0,16247955 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02239392 0,16196861 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02239392 0,16146087 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,02239392 0,16095631 ! enteric nervous system development GO:0048484 8 5 0,000 0,02239392 0,16045488 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02239392 0,15995658 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02239392 0,15946136 ! muscle cell proliferation GO:0033002 8 5 0,000 0,02239392 0,15896919 ! transcription termination GO:0006353 8 5 0,000 0,02239392 0,15848006 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,02239392 0,15799392 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,02239392 0,15751076 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,02239392 0,15703054 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,02239392 0,15655325 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02239392 0,15607884 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02239392 0,1556073 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02239392 0,15513861 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02239392 0,15467273 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02239392 0,15420963 ! apical protein localization GO:0045176 6 5 0,000 0,02239392 0,15374931 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,02239392 0,15329172 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02239392 0,15283685 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02239392 0,15238467 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02239392 0,15193516 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02239392 0,15148829 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,02239392 0,15104404 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,02239392 0,15060239 ! glial cell migration GO:0008347 10 5 0,000 0,02239392 0,15016332 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,02239392 0,1497268 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02239392 0,14929281 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02239392 0,14886132 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02239392 0,14843233 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02239392 0,1480058 ! neural plate development GO:0001840 6 5 0,000 0,02239392 0,14758171 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,02239392 0,14716005 ! regulation of sensory perception GO:0051931 6 5 0,000 0,02239392 0,14674079 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02239392 0,14632391 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,02239392 0,1459094 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,02239392 0,14549723 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02239392 0,14508737 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02239392 0,14467983 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02239392 0,14427456 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02239392 0,14387156 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02239392 0,1434708 ! spindle assembly GO:0051225 5 5 0,000 0,02239392 0,14307227 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02239392 0,14267595 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,02239392 0,14228182 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02239392 0,14188986 ! organ regeneration GO:0031100 7 5 0,000 0,02239392 0,14150005 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,02239392 0,14111238 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02239392 0,14072682 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,02239392 0,14034337 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02239392 0,13996201 GO:0055081|anion homeostasis, ! regulation of cellular component size GO:0032535 74 52 1,000 0,02310796 0,14403333 ! aging GO:0007568 79 52 1,000 0,02310796 0,14364405 ! regulation of neurotransmitter levels GO:0001505 73 53 1,000 0,0239448 0,14844485 ! kidney development GO:0001822 90 53 1,000 0,0239448 0,14804581 ! cell projection assembly GO:0030031 76 53 1,000 0,0239448 0,1476489 ! regulation of protein complex assembly GO:0043254 81 54 1,000 0,02479397 0,15247628 ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 0,02479397 0,15206968 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,02479397 0,15166524 ! nucleoside metabolic process GO:0009116 69 55 1,000 0,02565534 0,15651797 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,02652878 0,16141851 ! tRNA transcription GO:0009304 11 6 0,000 0,02681292 0,16271694 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02681292 0,16228874 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,02681292 0,16186278 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02681292 0,16143906 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02681292 0,16101755 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,02681292 0,16059823 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02681292 0,16018109 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02681292 0,15976611 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02681292 0,15935328 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02681292 0,15894258 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02681292 0,15853399 ! prostate gland development GO:0030850 9 6 0,000 0,02681292 0,15812749 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02681292 0,15772307 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02681292 0,15732071 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02681292 0,15692041 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,02681292 0,15652213 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02681292 0,15612587 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02681292 0,15573162 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02681292 0,15533935 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02681292 0,15494905 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,02681292 0,1545607 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,02681292 0,1541743 ! neuron adhesion GO:0007158 9 6 0,000 0,02681292 0,15378983 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,02681292 0,15340726 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02681292 0,1530266 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02681292 0,15264782 ! signal peptide processing GO:0006465 8 6 0,000 0,02681292 0,15227091 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02681292 0,15189586 ! mRNA stabilization GO:0048255 15 6 0,000 0,02681292 0,15152265 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,02681292 0,15115127 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02681292 0,15078171 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02681292 0,15041395 ! opsonization GO:0008228 8 6 0,000 0,02681292 0,15004798 ! erythrocyte maturation GO:0043249 6 6 0,000 0,02681292 0,14968379 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02681292 0,14932136 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02681292 0,14896068 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02681292 0,14860174 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02681292 0,14824452 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02681292 0,14788902 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02681292 0,14753522 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02681292 0,1471831 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02681292 0,14683267 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02681292 0,1464839 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02681292 0,14613678 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02681292 0,1457913 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02681292 0,14544745 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02681292 0,14510522 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02681292 0,1447646 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02681292 0,14442557 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02681292 0,14408813 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,02681292 0,14375226 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02681292 0,14341795 ! thymic T cell selection GO:0045061 12 6 0,000 0,02681292 0,1430852 ! protein lipoylation GO:0009249 10 6 0,000 0,02681292 0,14275398 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02681292 0,1424243 ! pigment granule organization GO:0048753 11 6 0,000 0,02681292 0,14209613 ! drug transport GO:0015893 6 6 0,000 0,02681292 0,14176947 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02681292 0,14144431 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,02681292 0,14112064 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02681292 0,14079845 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02681292 0,14047772 ! histidine metabolic process GO:0006547 6 6 0,000 0,02681292 0,14015845 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02681292 0,13984064 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02681292 0,13952425 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,02681292 0,1392093 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,02681292 0,13889577 ! adenohypophysis development GO:0021984 10 6 0,000 0,02681292 0,13858364 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02681292 0,13827292 ! hyperosmotic response GO:0006972 8 6 0,000 0,02681292 0,13796358 ! microtubule nucleation GO:0007020 10 6 0,000 0,02681292 0,13765563 ! ER overload response GO:0006983 7 6 0,000 0,02681292 0,13734904 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02681292 0,13704382 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02681292 0,13673996 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02681292 0,13643743 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02681292 0,13613625 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02681292 0,13583639 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02681292 0,13553785 ! response to dietary excess GO:0002021 7 6 0,000 0,02681292 0,13524061 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02681292 0,13494468 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,02681292 0,13465004 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02681292 0,13435669 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02681292 0,13406461 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02681292 0,1337738 GO:0046464|acylglycerol catabolic process, ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02681292 0,13348424 ! neuron apoptosis GO:0051402 8 6 0,000 0,02681292 0,13319594 ! organic alcohol transport GO:0015850 9 6 0,000 0,02681292 0,13290888 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,02681292 0,13262305 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02681292 0,13233846 ! male sex determination GO:0030238 9 6 0,000 0,02681292 0,13205508 ! carnitine transport GO:0015879 8 6 0,000 0,02681292 0,13177291 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02681292 0,13149194 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02681292 0,13121217 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02681292 0,13093359 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02681292 0,13065619 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02681292 0,13037996 ! parturition GO:0007567 12 6 0,000 0,02681292 0,13010489 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02681292 0,12983099 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02681292 0,12955824 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,02681292 0,12928663 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,02681292 0,12901615 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02681292 0,12874681 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02681292 0,12847858 ! macrophage differentiation GO:0030225 10 6 0,000 0,02681292 0,12821148 ! astrocyte development GO:0014002 14 6 0,000 0,02681292 0,12794548 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02681292 0,12768058 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02681292 0,12741678 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02681292 0,12715406 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02681292 0,12689243 ! eating behavior GO:0042755 6 6 0,000 0,02681292 0,12663187 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02681292 0,12637238 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02681292 0,12611395 ! response to copper ion GO:0046688 9 6 0,000 0,02681292 0,12585657 ! DNA topological change GO:0006265 8 6 0,000 0,02681292 0,12560024 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02681292 0,12534496 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,02681292 0,12509071 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02681292 0,12483749 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02681292 0,12458529 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02681292 0,12433411 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02681292 0,12408394 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,02681292 0,12383478 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02681292 0,12358661 ! gas homeostasis GO:0033483 11 6 0,000 0,02681292 0,12333944 ! hair follicle maturation GO:0048820 7 6 0,000 0,02681292 0,12309325 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02681292 0,12284805 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02681292 0,12260382 ! Schwann cell development GO:0014044 14 6 0,000 0,02681292 0,12236056 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02681292 0,12211826 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02681292 0,12187692 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02681292 0,12163653 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02681292 0,12139709 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02681292 0,12115859 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02681292 0,12092102 ! histone ubiquitination GO:0016574 7 6 0,000 0,02681292 0,12068438 ! regulation of meiosis GO:0040020 10 6 0,000 0,02681292 0,12044867 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,02681292 0,12021388 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02681292 0,11998 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02681292 0,11974703 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02681292 0,11951496 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02681292 0,11928379 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02681292 0,11905351 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02681292 0,11882412 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02681292 0,11859562 ! receptor internalization GO:0031623 9 6 0,000 0,02681292 0,11836798 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02681292 0,11814123 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02681292 0,11791533 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02681292 0,11769031 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02681292 0,11746613 ! protein deubiquitination GO:0016579 8 6 0,000 0,02681292 0,11724281 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02681292 0,11702034 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,02681292 0,11679871 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02681292 0,11657792 ! axonal fasciculation GO:0007413 9 6 0,000 0,02681292 0,11635796 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02681292 0,11613883 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02681292 0,11592053 ! midbrain development GO:0030901 6 6 0,000 0,02681292 0,11570304 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02681292 0,11548637 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02681292 0,11527051 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02681292 0,11505545 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02681292 0,11484119 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02681292 0,11462773 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02681292 0,11441507 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02681292 0,11420319 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02681292 0,11399209 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02681292 0,11378177 ! adult feeding behavior GO:0008343 6 6 0,000 0,02681292 0,11357223 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02681292 0,11336346 ! blastocyst growth GO:0001832 15 6 0,000 0,02681292 0,11315545 ! pigment granule transport GO:0051904 12 6 0,000 0,02681292 0,11294821 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02681292 0,11274172 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02681292 0,11253599 ! catecholamine transport GO:0051937 7 6 0,000 0,02681292 0,112331 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02681292 0,11212676 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02681292 0,11192327 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02681292 0,11172051 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02681292 0,11151848 ! protein prenylation GO:0018342 10 6 0,000 0,02681292 0,11131718 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02681292 0,11111661 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,02681292 0,11091676 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,02681292 0,11071763 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,02681292 0,11051921 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02681292 0,1103215 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 0,02741418 0,11259393 ! developmental maturation GO:0021700 75 57 1,000 0,02741418 0,11239323 ! actin filament organization GO:0007015 95 59 1,000 0,02922033 0,11958497 ! meiosis GO:0007126 96 61 1,000 0,03107282 0,12694047 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 1,000 0,03107282 0,1267154 ! urogenital system development GO:0001655 101 61 1,000 0,03107282 0,12649112 ! extracellular matrix organization GO:0030198 103 61 1,000 0,03107282 0,12626764 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,0312122 0,12661033 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,0312122 0,12638743 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,0312122 0,12616531 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,0312122 0,12594396 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0312122 0,1257234 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,0312122 0,1255036 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0312122 0,12528457 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,0312122 0,12506631 ! reproductive behavior GO:0019098 12 7 0,000 0,0312122 0,1248488 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,0312122 0,12463205 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,0312122 0,12441605 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,0312122 0,12420079 ! oligopeptide transport GO:0006857 11 7 0,000 0,0312122 0,12398629 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,0312122 0,12377252 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,0312122 0,12355948 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,0312122 0,12334718 ! RNA methylation GO:0001510 11 7 0,000 0,0312122 0,12313561 ! pericardium development GO:0060039 8 7 0,000 0,0312122 0,12292476 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,0312122 0,12271463 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,0312122 0,12250522 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0312122 0,12229652 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,0312122 0,12208854 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,0312122 0,12188125 ! lipoprotein transport GO:0042953 9 7 0,000 0,0312122 0,12167468 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,0312122 0,1214688 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0312122 0,12126361 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0312122 0,12105912 ! estrogen metabolic process GO:0008210 14 7 0,000 0,0312122 0,12085532 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,0312122 0,1206522 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,0312122 0,12044976 ! chemosensory behavior GO:0007635 9 7 0,000 0,0312122 0,12024801 ! microtubule bundle formation GO:0001578 8 7 0,000 0,0312122 0,12004692 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,0312122 0,11984651 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,0312122 0,11964677 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,0312122 0,11944769 ! leukocyte degranulation GO:0043299 10 7 0,000 0,0312122 0,11924927 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,0312122 0,11905151 ! reflex GO:0060004 12 7 0,000 0,0312122 0,1188544 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0312122 0,11865795 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,0312122 0,11846214 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0312122 0,11826698 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,0312122 0,11807247 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,0312122 0,11787859 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0312122 0,11768534 ! spinal cord patterning GO:0021511 7 7 0,000 0,0312122 0,11749273 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,0312122 0,11730075 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,0312122 0,1171094 ! adrenal gland development GO:0030325 17 7 0,000 0,0312122 0,11691866 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,0312122 0,11672855 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,0312122 0,11653906 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,0312122 0,11635018 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,0312122 0,11616191 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,0312122 0,11597425 ! endosome organization GO:0007032 10 7 0,000 0,0312122 0,11578719 ! thyroid hormone generation GO:0006590 11 7 0,000 0,0312122 0,11560074 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,0312122 0,11541489 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,0312122 0,11522963 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,0312122 0,11504497 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0312122 0,11486089 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,0312122 0,11467741 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0312122 0,11449451 ! galactose metabolic process GO:0006012 10 7 0,000 0,0312122 0,1143122 ! vesicle fusion GO:0006906 15 7 0,000 0,0312122 0,11413046 ! intracellular pH reduction GO:0051452 10 7 0,000 0,0312122 0,1139493 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,0312122 0,11376871 ! organ growth GO:0035265 11 7 0,000 0,0312122 0,1135887 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,0312122 0,11340926 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,0312122 0,11323038 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,0312122 0,11305206 ! retinol metabolic process GO:0042572 9 7 0,000 0,0312122 0,11287431 ! behavioral fear response GO:0001662 13 7 0,000 0,0312122 0,11269711 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,0312122 0,11252047 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,0312122 0,11234438 ! rRNA modification GO:0000154 12 7 0,000 0,0312122 0,11216884 ! protein heterooligomerization GO:0051291 10 7 0,000 0,0312122 0,11199385 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0312122 0,11181941 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,0312122 0,1116455 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,0312122 0,11147214 ! intermediate filament organization GO:0045109 11 7 0,000 0,0312122 0,11129932 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,0312122 0,11112703 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,0312122 0,11095527 ! fibrinolysis GO:0042730 9 7 0,000 0,0312122 0,11078404 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,0312122 0,11061334 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,0312122 0,11044317 ! B cell lineage commitment GO:0002326 17 7 0,000 0,0312122 0,11027352 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,0312122 0,11010439 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,0312122 0,10993577 ! response to tropane GO:0014073 13 7 0,000 0,0312122 0,10976767 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,0312122 0,10960009 ! melanosome localization GO:0032400 10 7 0,000 0,0312122 0,10943302 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,0312122 0,10926645 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,0312122 0,10910039 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,0312122 0,10893484 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,0312122 0,10876979 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,0312122 0,10860523 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,0312122 0,10844118 ! mast cell activation GO:0045576 9 7 0,000 0,0312122 0,10827762 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,0312122 0,10811455 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,0312122 0,10795197 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,0312122 0,10778988 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,0312122 0,10762827 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,0312122 0,10746715 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,0312122 0,10730652 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,0312122 0,10714636 ! T cell lineage commitment GO:0002360 12 7 0,000 0,0312122 0,10698668 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,0312122 0,10682747 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,0312122 0,10666874 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,0312122 0,10651047 ! regulation of lipid transport GO:0032368 13 7 0,000 0,0312122 0,10635268 ! response to tumor cell GO:0002347 12 7 0,000 0,0312122 0,10619535 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,0312122 0,10603849 ! neuroblast proliferation GO:0007405 13 7 0,000 0,0312122 0,10588209 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,0312122 0,10572615 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,0312122 0,10557068 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,0312122 0,10541565 ! diuresis GO:0030146 12 7 0,000 0,0312122 0,10526108 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,0312122 0,10510697 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,0312122 0,1049533 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0312122 0,10480009 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,0312122 0,10464732 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0312122 0,10449499 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0312122 0,10434311 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0312122 0,10419167 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,0312122 0,10404067 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,0312122 0,1038901 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,0312122 0,10373997 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,0312122 0,10359027 ! lymph node development GO:0048535 9 7 0,000 0,0312122 0,10344101 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,0312122 0,10329217 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,0312122 0,10314376 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0312122 0,10299578 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,0312122 0,10284822 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,0312122 0,10270109 ! ATP catabolic process GO:0006200 10 7 0,000 0,0312122 0,10255437 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,0312122 0,10240807 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,0312122 0,10226219 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,0312122 0,10211673 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,0312122 0,10197167 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,0312122 0,10182703 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,0312122 0,1016828 ! muscle adaptation GO:0043500 12 7 0,000 0,0312122 0,10153898 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,0312122 0,10139556 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,0312122 0,10125255 ! retina homeostasis GO:0001895 9 7 0,000 0,0312122 0,10110994 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,0312122 0,10096773 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,0312122 0,10082593 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,0312122 0,10068451 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,0312122 0,1005435 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,0312122 0,10040288 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,0312122 0,10026265 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0312122 0,10012282 ! neurotransmitter transport GO:0006836 81 62 1,000 0,03201614 0,10255867 ! meiotic cell cycle GO:0051321 97 62 1,000 0,03201614 0,10241603 ! organelle localization GO:0051640 96 62 1,000 0,03201614 0,10227379 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,03297069 0,10517697 GO:0090046|regulation of transcription regulator activity, ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 0,03393635 0,10810749 ! neuropeptide signaling pathway GO:0007218 79 64 1,000 0,03393635 0,10795796 ! B cell activation GO:0042113 104 65 1,000 0,034913 0,11091146 ! positive regulation of T cell activation GO:0050870 94 65 1,000 0,034913 0,11075848 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,03559184 0,11275652 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,03559184 0,11260142 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,03559184 0,11244675 ! axon extension GO:0048675 11 8 0,000 0,03559184 0,1122925 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,03559184 0,11213868 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,03559184 0,11198527 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,03559184 0,11183229 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,03559184 0,11167972 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,03559184 0,11152757 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,03559184 0,11137583 ! phosphate transport GO:0006817 10 8 0,000 0,03559184 0,1112245 ! N-glycan processing GO:0006491 12 8 0,000 0,03559184 0,11107359 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,03559184 0,11092308 ! UTP metabolic process GO:0046051 8 8 0,000 0,03559184 0,11077298 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,03559184 0,11062329 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,03559184 0,110474 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,03559184 0,11032511 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,03559184 0,11017663 ! succinate metabolic process GO:0006105 14 8 0,000 0,03559184 0,11002854 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,03559184 0,10988085 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,03559184 0,10973356 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03559184 0,10958666 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,03559184 0,10944015 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,03559184 0,10929404 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,03559184 0,10914831 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,03559184 0,10900298 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,03559184 0,10885802 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03559184 0,10871346 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,03559184 0,10856928 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,03559184 0,10842548 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,03559184 0,10828206 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,03559184 0,10813902 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,03559184 0,10799635 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,03559184 0,10785406 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,03559184 0,10771215 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,03559184 0,10757061 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,03559184 0,10742944 ! astrocyte differentiation GO:0048708 16 8 0,000 0,03559184 0,10728864 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,03559184 0,10714821 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,03559184 0,10700815 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,03559184 0,10686845 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,03559184 0,10672912 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,03559184 0,10659015 ! melanin metabolic process GO:0006582 12 8 0,000 0,03559184 0,10645154 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,03559184 0,10631329 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03559184 0,1061754 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,03559184 0,10603787 ! macrophage activation GO:0042116 12 8 0,000 0,03559184 0,10590069 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,03559184 0,10576387 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,03559184 0,1056274 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,03559184 0,10549128 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,03559184 0,10535551 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03559184 0,1052201 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,03559184 0,10508503 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,03559184 0,1049503 ! ruffle organization GO:0031529 11 8 0,000 0,03559184 0,10481592 ! osteoblast development GO:0002076 13 8 0,000 0,03559184 0,10468189 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,03559184 0,10454819 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,03559184 0,10441484 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,03559184 0,10428183 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,03559184 0,10414915 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,03559184 0,10401682 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,03559184 0,10388482 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,03559184 0,10375315 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,03559184 0,10362182 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,03559184 0,10349082 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,03559184 0,10336014 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,03559184 0,1032298 ! oligodendrocyte development GO:0014003 8 8 0,000 0,03559184 0,10309979 ! segment specification GO:0007379 10 8 0,000 0,03559184 0,10297011 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,03559184 0,10284075 ! cellular extravasation GO:0045123 11 8 0,000 0,03559184 0,10271171 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,03559184 0,102583 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,03559184 0,10245461 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,03559184 0,10232654 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,03559184 0,10219879 ! snRNA metabolic process GO:0016073 10 8 0,000 0,03559184 0,10207137 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,03559184 0,10194425 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,03559184 0,10181746 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,03559184 0,10169097 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,03559184 0,10156481 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,03559184 0,10143895 ! nucleosome disassembly GO:0006337 12 8 0,000 0,03559184 0,10131341 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,03559184 0,10118818 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,03559184 0,10106325 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,03559184 0,10093864 ! icosanoid secretion GO:0032309 12 8 0,000 0,03559184 0,10081433 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,03559184 0,10069033 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03559184 0,10056663 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,03559184 0,10044323 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,03559184 0,10032014 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,03559184 0,10019735 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,03559184 0,10007486 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,03559184 0,09995267 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,03559184 0,09983077 ! sterol catabolic process GO:0016127 9 8 0,000 0,03559184 0,09970918 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,03559184 0,09958788 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,03559184 0,09946687 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,03559184 0,09934616 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,03559184 0,09922574 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03559184 0,09910561 ! prophase GO:0051324 11 8 0,000 0,03559184 0,09898577 ! S phase GO:0051320 8 8 0,000 0,03559184 0,09886623 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,03559184 0,09874697 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,03559184 0,09862799 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,03559184 0,09850931 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,03559184 0,09839091 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,03559184 0,09827279 ! hormone catabolic process GO:0042447 13 8 0,000 0,03559184 0,09815496 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,03559184 0,09803741 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,03559184 0,09792014 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,03559184 0,09780315 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,03559184 0,09768644 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,03559184 0,09757001 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,03559184 0,09745385 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,03559184 0,09733797 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03559184 0,09722237 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,03559184 0,09710704 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,03559184 0,09699198 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,03559184 0,0968772 ! regulation of embryonic development GO:0045995 16 8 0,000 0,03559184 0,09676269 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03559184 0,09664845 GO:0000076|DNA replication checkpoint, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,03559184 0,09653447 ! regulation of actin filament-based process GO:0032970 99 66 1,000 0,03590052 0,09725701 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,03590052 0,09714259 ! learning or memory GO:0007611 123 68 1,000 0,03790774 0,10245334 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,03995193 0,10785146 ! regulation of developmental growth GO:0048638 13 9 0,000 0,03995193 0,10772502 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,03995193 0,10759888 ! telencephalon cell migration GO:0022029 16 9 0,000 0,03995193 0,10747304 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,03995193 0,10734748 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,03995193 0,10722222 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,03995193 0,10709726 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,03995193 0,10697258 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03995193 0,10684819 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,03995193 0,1067241 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,03995193 0,10660029 ! GTP metabolic process GO:0046039 9 9 0,000 0,03995193 0,10647676 ! elastic fiber assembly GO:0048251 13 9 0,000 0,03995193 0,10635353 ! social behavior GO:0035176 14 9 0,000 0,03995193 0,10623057 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,03995193 0,10610791 ! artery development GO:0060840 19 9 0,000 0,03995193 0,10598552 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,03995193 0,10586342 ! regulation of glycolysis GO:0006110 15 9 0,000 0,03995193 0,10574159 ! response to pain GO:0048265 16 9 0,000 0,03995193 0,10562005 ! protein complex disassembly GO:0043241 17 9 0,000 0,03995193 0,10549879 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,03995193 0,1053778 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,03995193 0,1052571 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,03995193 0,10513667 ! lung alveolus development GO:0048286 17 9 0,000 0,03995193 0,10501651 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,03995193 0,10489663 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,03995193 0,10477702 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,03995193 0,10465768 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,03995193 0,10453862 ! ventral spinal cord development GO:0021517 11 9 0,000 0,03995193 0,10441982 ! protein targeting to ER GO:0045047 19 9 0,000 0,03995193 0,1043013 ! T cell selection GO:0045058 18 9 0,000 0,03995193 0,10418305 ! endoderm development GO:0007492 12 9 0,000 0,03995193 0,10406506 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,03995193 0,10394734 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,03995193 0,10382988 ! arginine catabolic process GO:0006527 10 9 0,000 0,03995193 0,10371269 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,03995193 0,10359577 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,03995193 0,10347911 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,03995193 0,10336271 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03995193 0,10324657 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,03995193 0,10313069 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,03995193 0,10301507 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,03995193 0,10289972 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,03995193 0,10278462 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03995193 0,10266977 ! mannose metabolic process GO:0006013 9 9 0,000 0,03995193 0,10255519 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,03995193 0,10244085 ! receptor clustering GO:0043113 15 9 0,000 0,03995193 0,10232678 ! epithelial cell development GO:0002064 10 9 0,000 0,03995193 0,10221295 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,03995193 0,10209938 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,03995193 0,10198607 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,03995193 0,101873 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,03995193 0,10176018 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,03995193 0,10164762 ! motor axon guidance GO:0008045 14 9 0,000 0,03995193 0,1015353 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,03995193 0,10142323 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,03995193 0,10131141 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,03995193 0,10119983 ! blastoderm segmentation GO:0007350 11 9 0,000 0,03995193 0,1010885 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,03995193 0,10097741 ! DNA ligation GO:0006266 14 9 0,000 0,03995193 0,10086657 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,03995193 0,10075597 ! response to amine stimulus GO:0014075 13 9 0,000 0,03995193 0,10064561 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,03995193 0,1005355 ! erythrocyte development GO:0048821 11 9 0,000 0,03995193 0,10042562 ! renal water homeostasis GO:0003091 14 9 0,000 0,03995193 0,10031599 ! postreplication repair GO:0006301 11 9 0,000 0,03995193 0,10020659 ! mRNA cleavage GO:0006379 13 9 0,000 0,03995193 0,10009744 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,03995193 0,09998852 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,03995193 0,09987983 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,03995193 0,09977139 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,03995193 0,09966317 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,03995193 0,0995552 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,03995193 0,09944745 ! acid secretion GO:0046717 14 9 0,000 0,03995193 0,09933994 ! musculoskeletal movement GO:0050881 11 9 0,000 0,03995193 0,09923266 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,03995193 0,09912562 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,03995193 0,0990188 ! oocyte differentiation GO:0009994 12 9 0,000 0,03995193 0,09891221 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,03995193 0,09880586 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,03995193 0,09869973 ! spleen development GO:0048536 15 9 0,000 0,03995193 0,09859383 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,03995193 0,09848815 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,03995193 0,0983827 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,03995193 0,09827748 ! blastocyst formation GO:0001825 12 9 0,000 0,03995193 0,09817248 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,03995193 0,09806771 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,03995193 0,09796316 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,03995193 0,09785883 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,03995193 0,09775473 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03995193 0,09765085 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,03995193 0,09754718 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,03995193 0,09744374 ! prepulse inhibition GO:0060134 14 9 0,000 0,03995193 0,09734051 ! insulin secretion GO:0030073 17 9 0,000 0,03995193 0,09723751 ! sequestering of metal ion GO:0051238 11 9 0,000 0,03995193 0,09713472 ! response to nicotine GO:0035094 16 9 0,000 0,03995193 0,09703215 ! establishment of cell polarity GO:0030010 12 9 0,000 0,03995193 0,0969298 ! nucleus localization GO:0051647 15 9 0,000 0,03995193 0,09682766 ! regulation of synapse organization GO:0050807 12 9 0,000 0,03995193 0,09672573 ! localization within membrane GO:0051668 15 9 0,000 0,03995193 0,09662402 ! response to metal ion GO:0010038 103 70 1,000 0,03995707 0,09653494 ! regulation of catabolic process GO:0009894 106 70 1,000 0,03995707 0,09643365 ! regulation of peptidase activity GO:0052547 106 72 1,000 0,04204763 0,1013727 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 0,04417852 0,10639854 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,04417852 0,10628724 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,04429256 0,10645025 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,04429256 0,10633913 ! neuron fate specification GO:0048665 11 10 0,000 0,04429256 0,10622825 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,04429256 0,10611759 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,04429256 0,10600717 ! thyroid gland development GO:0030878 19 10 0,000 0,04429256 0,10589698 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,04429256 0,10578701 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,04429256 0,10567727 ! synapsis GO:0007129 13 10 0,000 0,04429256 0,10556776 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,04429256 0,10545848 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,04429256 0,10534942 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,04429256 0,10524059 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,04429256 0,10513198 ! sulfate transport GO:0008272 12 10 0,000 0,04429256 0,1050236 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,04429256 0,10491544 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,04429256 0,1048075 ! androgen metabolic process GO:0008209 13 10 0,000 0,04429256 0,10469979 ! phospholipid efflux GO:0033700 16 10 0,000 0,04429256 0,10459229 ! hippocampus development GO:0021766 19 10 0,000 0,04429256 0,10448502 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,04429256 0,10437796 ! blood vessel remodeling GO:0001974 21 10 0,000 0,04429256 0,10427113 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,04429256 0,10416451 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,04429256 0,10405811 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,04429256 0,10395193 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,04429256 0,10384596 ! pathogenesis GO:0009405 13 10 0,000 0,04429256 0,10374021 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,04429256 0,10363468 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04429256 0,10352936 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,04429256 0,10342425 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,04429256 0,10331936 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,04429256 0,10321468 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,04429256 0,10311021 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,04429256 0,10300596 ! melanocyte differentiation GO:0030318 15 10 0,000 0,04429256 0,10290191 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,04429256 0,10279807 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,04429256 0,10269445 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04429256 0,10259103 ! response to X-ray GO:0010165 16 10 0,000 0,04429256 0,10248782 ! B cell proliferation GO:0042100 14 10 0,000 0,04429256 0,10238481 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,04429256 0,10228202 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,04429256 0,10217943 ! forebrain cell migration GO:0021885 17 10 0,000 0,04429256 0,10207704 ! lipid digestion GO:0044241 15 10 0,000 0,04429256 0,10197487 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,04429256 0,10187289 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,04429256 0,10177112 ! UV protection GO:0009650 14 10 0,000 0,04429256 0,10166955 ! entry into host cell GO:0030260 20 10 0,000 0,04429256 0,10156819 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,04429256 0,10146702 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,04429256 0,10136606 ! negative regulation of ossification GO:0030279 19 10 0,000 0,04429256 0,1012653 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,04429256 0,10116474 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,04429256 0,10106438 ! regulation of bone resorption GO:0045124 24 10 0,000 0,04429256 0,10096421 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,04429256 0,10086425 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,04429256 0,10076448 ! regulation of organ growth GO:0046620 11 10 0,000 0,04429256 0,10066491 ! response to dsRNA GO:0043331 18 10 0,000 0,04429256 0,10056554 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,04429256 0,10046636 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04429256 0,10036738 ! embryonic axis specification GO:0000578 12 10 0,000 0,04429256 0,10026859 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,04429256 0,10017 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,04429256 0,1000716 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,04429256 0,0999734 ! cranial nerve development GO:0021545 12 10 0,000 0,04429256 0,09987538 ! fucose catabolic process GO:0019317 16 10 0,000 0,04429256 0,09977756 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,04429256 0,09967993 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,04429256 0,09958249 ! protein sumoylation GO:0016925 12 10 0,000 0,04429256 0,09948525 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,04429256 0,09938819 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04429256 0,09929132 ! zymogen activation GO:0031638 14 10 0,000 0,04429256 0,09919464 ! salivary gland development GO:0007431 22 10 0,000 0,04429256 0,09909814 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04429256 0,09900184 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,04429256 0,09890572 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,04429256 0,09880979 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,04429256 0,09871404 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,04429256 0,09861848 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,04429256 0,09852311 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04429256 0,09842791 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,04429256 0,09833291 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,04429256 0,09823808 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,04429256 0,09814344 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,04429256 0,09804898 ! detection of bacterium GO:0016045 10 10 0,000 0,04429256 0,0979547 ! embryonic gut development GO:0048566 11 10 0,000 0,04429256 0,09786061 ! activation of innate immune response GO:0002218 10 10 0,000 0,04429256 0,09776669 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,04429256 0,09767295 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,04429256 0,0975794 ! developmental induction GO:0031128 13 10 0,000 0,04429256 0,09748602 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,04429256 0,09739282 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,04429256 0,0972998 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,04429256 0,09720696 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,04429256 0,09711429 ! response to inorganic substance GO:0010035 115 75 1,000 0,04525882 0,09913837 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,04634887 0,1014295 ! regulation of DNA binding GO:0051101 119 77 1,000 0,04744857 0,10373737 ! gland development GO:0048732 148 77 1,000 0,04744857 0,10363885 ! carbohydrate biosynthetic process GO:0016051 97 77 1,000 0,04744857 0,10354052 ! rRNA transcription GO:0009303 17 11 0,000 0,04861381 0,10598272 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,04861381 0,10588236 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,04861381 0,10578218 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,04861381 0,1056822 ! virus-host interaction GO:0019048 17 11 0,000 0,04861381 0,10558241 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,04861381 0,1054828 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,04861381 0,10538338 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,04861381 0,10528415 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,04861381 0,10518511 ! RNA polyadenylation GO:0043631 19 11 0,000 0,04861381 0,10508625 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,04861381 0,10498757 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,04861381 0,10488909 ! mating GO:0007618 14 11 0,000 0,04861381 0,10479078 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,04861381 0,10469267 ! T cell proliferation GO:0042098 20 11 0,000 0,04861381 0,10459473 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,04861381 0,10449698 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,04861381 0,10439941 ! bone resorption GO:0045453 16 11 0,000 0,04861381 0,10430202 ! regulated secretory pathway GO:0045055 14 11 0,000 0,04861381 0,10420482 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,04861381 0,10410779 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,04861381 0,10401095 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,04861381 0,10391428 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,04861381 0,1038178 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,04861381 0,10372149 ! syncytium formation GO:0006949 15 11 0,000 0,04861381 0,10362536 ! plasma membrane organization GO:0007009 18 11 0,000 0,04861381 0,10352941 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,04861381 0,10343364 ! focal adhesion formation GO:0048041 24 11 0,000 0,04861381 0,10333805 ! mitotic spindle organization GO:0007052 15 11 0,000 0,04861381 0,10324263 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,04861381 0,10314739 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,04861381 0,10305232 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,04861381 0,10295743 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,04861381 0,10286271 ! adult heart development GO:0007512 11 11 0,000 0,04861381 0,10276817 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,04861381 0,1026738 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,04861381 0,1025796 ! temperature homeostasis GO:0001659 16 11 0,000 0,04861381 0,10248558 ! L-glutamate transport GO:0015813 16 11 0,000 0,04861381 0,10239173 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,04861381 0,10229805 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,04861381 0,10220454 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,04861381 0,1021112 ! stem cell development GO:0048864 29 11 0,000 0,04861381 0,10201804 GO:0019827|stem cell maintenance, ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,04861381 0,10192504 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,04861381 0,10183221 ! vasoconstriction GO:0042310 15 11 0,000 0,04861381 0,10173955 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,04861381 0,10164706 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,04861381 0,10155474 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,04861381 0,10146258 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,04861381 0,1013706 ! ribosome assembly GO:0042255 13 11 0,000 0,04861381 0,10127877 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,04861381 0,10118712 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,04861381 0,10109563 ! chromatin silencing GO:0006342 19 11 0,000 0,04861381 0,10100431 ! nucleosome positioning GO:0016584 13 11 0,000 0,04861381 0,10091315 ! T cell homeostasis GO:0043029 20 11 0,000 0,04861381 0,10082215 ! regulation of isotype switching GO:0045191 19 11 0,000 0,04861381 0,10073132 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,04861381 0,10064065 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,04861381 0,10055015 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,04861381 0,10045981 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,04861381 0,10036963 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,04861381 0,10027961 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,04861381 0,10018976 ! oxygen transport GO:0015671 15 11 0,000 0,04861381 0,10010006 ! male genitalia development GO:0030539 13 11 0,000 0,04861381 0,10001052 ! cholesterol efflux GO:0033344 19 11 0,000 0,04861381 0,09992115 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,04861381 0,09983193 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,04861381 0,09974288 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,04861381 0,09965398 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,04861381 0,09956524 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,04861381 0,09947666 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,04861381 0,09938824 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,04861381 0,09929997 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,04861381 0,09921186 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,04861381 0,09912391 ! lysogeny GO:0030069 18 11 0,000 0,04861381 0,09903611 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,04861381 0,09894847 ! acrosome reaction GO:0007340 13 11 0,000 0,04861381 0,09886098 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,04861381 0,09877365 ! T cell activation GO:0042110 134 79 1,000 0,04967648 0,1008437 ! forebrain development GO:0030900 131 80 1,000 0,05080449 0,10304261 ! mRNA transport GO:0051028 121 81 1,000 0,05194171 0,10525634 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,05194171 0,10516368 GO:0002696|positive regulation of leukocyte activation, ! lactation GO:0007595 20 12 0,000 0,05291577 0,10704157 ! reproductive cellular process GO:0048610 14 12 0,000 0,05291577 0,10694751 ! tRNA modification GO:0006400 14 12 0,000 0,05291577 0,10685362 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,05291577 0,10675989 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,05291577 0,10666632 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,05291577 0,10657292 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,05291577 0,10647968 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,05291577 0,1063866 ! non-recombinational repair GO:0000726 19 12 0,000 0,05291577 0,10629369 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,05291577 0,10620093 ! peroxisomal transport GO:0043574 21 12 0,000 0,05291577 0,10610834 ! cartilage condensation GO:0001502 18 12 0,000 0,05291577 0,10601591 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,05291577 0,10592365 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,05291577 0,10583154 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,05291577 0,10573959 ! heart looping GO:0001947 15 12 0,000 0,05291577 0,1056478 ! palate development GO:0060021 15 12 0,000 0,05291577 0,10555618 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,05291577 0,10546471 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,05291577 0,10537339 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,05291577 0,10528224 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,05291577 0,10519124 ! arginine metabolic process GO:0006525 13 12 0,000 0,05291577 0,10510041 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,05291577 0,10500972 ! methionine metabolic process GO:0006555 13 12 0,000 0,05291577 0,1049192 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,05291577 0,10482883 ! Golgi organization GO:0007030 18 12 0,000 0,05291577 0,10473861 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,05291577 0,10464856 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,05291577 0,10455865 ! monoamine transport GO:0015844 13 12 0,000 0,05291577 0,1044689 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05291577 0,10437931 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,05291577 0,10428986 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,05291577 0,10420057 ! L-amino acid transport GO:0015807 20 12 0,000 0,05291577 0,10411144 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,05291577 0,10402245 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,05291577 0,10393362 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,05291577 0,10384494 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05291577 0,10375641 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,05291577 0,10366803 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,05291577 0,1035798 ! cerebellum development GO:0021549 13 12 0,000 0,05291577 0,10349173 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,05291577 0,1034038 ! histone acetylation GO:0016573 23 12 0,000 0,05291577 0,10331602 ! histone methylation GO:0016571 15 12 0,000 0,05291577 0,10322839 ! autonomic nervous system development GO:0048483 23 12 0,000 0,05291577 0,10314091 ! gland morphogenesis GO:0022612 23 12 0,000 0,05291577 0,10305357 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,05291577 0,10296639 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,05291577 0,10287935 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,05291577 0,10279246 ! response to gamma radiation GO:0010332 20 12 0,000 0,05291577 0,10270571 ! regulation of epidermis development GO:0045682 17 12 0,000 0,05291577 0,10261912 ! intestinal absorption GO:0050892 19 12 0,000 0,05291577 0,10253266 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,05291577 0,10244636 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,05291577 0,10236019 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,05291577 0,10227418 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,05291577 0,1021883 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,05291577 0,10210258 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,05291577 0,10201699 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,05291577 0,10193155 ! microspike assembly GO:0030035 23 12 0,000 0,05291577 0,10184625 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,05291577 0,1017611 ! response to cold GO:0009409 14 12 0,000 0,05291577 0,10167608 ! ossification GO:0001503 134 82 1,000 0,05308806 0,10192199 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 1,000 0,05308806 0,10183698 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 0,0565808 0,10844652 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,0565808 0,10835623 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,05719852 0,10944808 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,05719852 0,1093571 ! cGMP metabolic process GO:0046068 16 13 0,000 0,05719852 0,10926628 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,05719852 0,1091756 ! water transport GO:0006833 17 13 0,000 0,05719852 0,10908507 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,05719852 0,1089947 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,05719852 0,10890447 ! lipid localization GO:0010876 24 13 0,000 0,05719852 0,10881439 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,05719852 0,10872446 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,05719852 0,10863468 ! organelle fusion GO:0048284 28 13 0,000 0,05719852 0,10854505 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,05719852 0,10845556 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,05719852 0,10836622 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,05719852 0,10827703 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,05719852 0,10818799 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,05719852 0,10809909 ! response to hexose stimulus GO:0009746 19 13 0,000 0,05719852 0,10801034 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,05719852 0,10792174 ! glutamate metabolic process GO:0006536 18 13 0,000 0,05719852 0,10783328 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,05719852 0,10774496 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,05719852 0,10765679 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,05719852 0,10756876 ! NAD metabolic process GO:0019674 21 13 0,000 0,05719852 0,10748088 ! exocrine system development GO:0035272 27 13 0,000 0,05719852 0,10739314 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,05719852 0,10730554 ! bone mineralization GO:0030282 15 13 0,000 0,05719852 0,10721809 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,05719852 0,10713078 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,05719852 0,10704361 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,05719852 0,10695658 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,05719852 0,1068697 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,05719852 0,10678295 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,05719852 0,10669635 ! genitalia development GO:0048806 15 13 0,000 0,05719852 0,10660988 ! regulation of cellular pH GO:0030641 20 13 0,000 0,05719852 0,10652356 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,05719852 0,10643738 ! cellular pigmentation GO:0033059 24 13 0,000 0,05719852 0,10635133 ! tissue regeneration GO:0042246 21 13 0,000 0,05719852 0,10626543 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,05719852 0,10617966 ! cofactor transport GO:0051181 19 13 0,000 0,05719852 0,10609403 ! NADP metabolic process GO:0006739 18 13 0,000 0,05719852 0,10600854 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,05719852 0,10592319 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,05719852 0,10583797 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05719852 0,10575289 ! gas transport GO:0015669 18 13 0,000 0,05719852 0,10566795 ! regulation of RNA stability GO:0043487 28 13 0,000 0,05719852 0,10558314 ! heme biosynthetic process GO:0006783 20 13 0,000 0,05719852 0,10549847 ! regulation of axon extension GO:0030516 23 13 0,000 0,05719852 0,10541394 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,05719852 0,10532954 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,05719852 0,10524528 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,05719852 0,10516115 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,05719852 0,10507715 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,05719852 0,10499329 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,05719852 0,10490957 ! cellular defense response GO:0006968 102 87 1,000 0,05895301 0,10804138 ! establishment of RNA localization GO:0051236 128 88 1,000 0,06015194 0,11015084 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! regulation of T cell activation GO:0050863 128 89 1,000 0,06135927 0,11227234 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,06146215 0,11237118 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,06146215 0,11228192 ! superoxide anion generation GO:0042554 18 14 0,000 0,06146215 0,11219281 ! neuron maturation GO:0042551 21 14 0,000 0,06146215 0,11210384 ! regulation of S phase GO:0033261 18 14 0,000 0,06146215 0,11201501 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,06146215 0,11192632 ! myotube differentiation GO:0014902 21 14 0,000 0,06146215 0,11183777 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,06146215 0,11174936 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,06146215 0,11166109 ! inositol metabolic process GO:0006020 20 14 0,000 0,06146215 0,11157296 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,06146215 0,11148497 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,06146215 0,11139712 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,06146215 0,1113094 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,06146215 0,11122183 ! gene silencing by RNA GO:0031047 20 14 0,000 0,06146215 0,11113439 ! response to cAMP GO:0051591 19 14 0,000 0,06146215 0,11104709 ! limbic system development GO:0021761 25 14 0,000 0,06146215 0,11095992 ! startle response GO:0001964 21 14 0,000 0,06146215 0,1108729 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,06146215 0,110786 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,06146215 0,11069925 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,06146215 0,11061263 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,06146215 0,11052615 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,06146215 0,1104398 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,06146215 0,11035358 ! glycine metabolic process GO:0006544 22 14 0,000 0,06146215 0,1102675 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,06146215 0,11018156 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,06146215 0,11009575 ! regulation of heart rate GO:0002027 23 14 0,000 0,06146215 0,11001007 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,06146215 0,10992453 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,06146215 0,10983912 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,06146215 0,10975384 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,06146215 0,10966869 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,06146215 0,10958368 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,06146215 0,10949879 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,06146215 0,10941404 ! axon cargo transport GO:0008088 27 14 0,000 0,06146215 0,10932942 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,06146215 0,10924493 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,06146215 0,10916057 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,06146215 0,10907634 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,06146215 0,10899224 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06146215 0,10890828 ! mRNA splice site selection GO:0006376 26 14 0,000 0,06146215 0,10882444 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,06146215 0,10874072 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,06146215 0,10865714 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,06146215 0,10857369 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,06146215 0,10849036 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,06146215 0,10840716 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,06146215 0,10832409 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,06146215 0,10824115 ! muscle maintenance GO:0046716 19 14 0,000 0,06146215 0,10815833 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,06146215 0,10807564 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,06146215 0,10799308 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,06146215 0,10791064 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,06146215 0,10782833 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,06146215 0,10774614 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,06146215 0,10766408 ! cilium assembly GO:0042384 20 14 0,000 0,06146215 0,10758215 ! peptide hormone secretion GO:0030072 23 14 0,000 0,06146215 0,10750034 ! response to virus GO:0009615 122 91 1,000 0,06379879 0,11150245 ! RNA localization GO:0006403 135 91 1,000 0,06379879 0,11141778 ! cell fate commitment GO:0045165 141 92 1,000 0,06503078 0,11348315 ! DNA recombination GO:0006310 146 92 1,000 0,06503078 0,11339711 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,06570674 0,11448901 ! positive regulation of cell size GO:0045793 20 15 0,000 0,06570674 0,11440234 ! metencephalon development GO:0022037 19 15 0,000 0,06570674 0,11431581 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,06570674 0,1142294 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,06570674 0,11414312 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,06570674 0,11405698 ! skin development GO:0043588 25 15 0,000 0,06570674 0,11397096 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,06570674 0,11388508 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,06570674 0,11379932 ! lipid phosphorylation GO:0046834 23 15 0,000 0,06570674 0,11371369 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,06570674 0,11362819 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,06570674 0,11354282 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,06570674 0,11345758 ! bile acid metabolic process GO:0008206 22 15 0,000 0,06570674 0,11337247 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,06570674 0,11328748 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,06570674 0,11320262 ! adult walking behavior GO:0007628 25 15 0,000 0,06570674 0,11311789 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,06570674 0,11303328 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,06570674 0,1129488 ! myoblast differentiation GO:0045445 27 15 0,000 0,06570674 0,11286445 ! centrosome cycle GO:0007098 16 15 0,000 0,06570674 0,11278022 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,06570674 0,11269612 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,06570674 0,11261214 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,06570674 0,11252829 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,06570674 0,11244457 ! cerebral cortex development GO:0021987 29 15 0,000 0,06570674 0,11236096 ! response to osmotic stress GO:0006970 22 15 0,000 0,06570674 0,11227749 ! vesicle coating GO:0006901 25 15 0,000 0,06570674 0,11219413 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,06570674 0,1121109 ! DNA integration GO:0015074 22 15 0,000 0,06570674 0,1120278 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,06570674 0,11194481 ! peptide secretion GO:0002790 27 15 0,000 0,06570674 0,11186195 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,06570674 0,11177921 ! regulation of vasodilation GO:0042312 24 15 0,000 0,06570674 0,1116966 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,06570674 0,1116141 ! neuron recognition GO:0008038 22 15 0,000 0,06570674 0,11153173 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,06570674 0,11144948 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,06570674 0,11136735 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,06570674 0,11128534 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,06570674 0,11120346 ! biomineral formation GO:0031214 18 15 0,000 0,06570674 0,11112169 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,06570674 0,11104004 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,06570674 0,11095851 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,06570674 0,11087711 ! dopamine metabolic process GO:0042417 30 15 0,000 0,06570674 0,11079582 ! organic cation transport GO:0015695 19 15 0,000 0,06570674 0,11071465 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,06570674 0,1106336 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,06570674 0,11055267 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,06570674 0,11047185 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,06570674 0,11039116 ! peptide hormone processing GO:0016486 19 15 0,000 0,06570674 0,11031058 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,06570674 0,11023012 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,06627079 0,11109535 ! regulation of binding GO:0051098 151 95 1,000 0,0687745 0,11520856 ! protein secretion GO:0009306 27 16 0,000 0,06993237 0,11706292 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,06993237 0,11697779 ! hormone secretion GO:0046879 25 16 0,000 0,06993237 0,11689277 ! bone remodeling GO:0046849 24 16 0,000 0,06993237 0,11680789 ! endothelial cell migration GO:0043542 22 16 0,000 0,06993237 0,11672312 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,06993237 0,11663848 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,06993237 0,11655395 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,06993237 0,11646956 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,06993237 0,11638528 ! glial cell development GO:0021782 24 16 0,000 0,06993237 0,11630113 ! patterning of blood vessels GO:0001569 24 16 0,000 0,06993237 0,11621709 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,06993237 0,11613318 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,06993237 0,11604939 ! protein polyubiquitination GO:0000209 26 16 0,000 0,06993237 0,11596572 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,06993237 0,11588217 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,06993237 0,11579875 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,06993237 0,11571544 ! fructose metabolic process GO:0006000 20 16 0,000 0,06993237 0,11563225 ! regulation of protein binding GO:0043393 27 16 0,000 0,06993237 0,11554918 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,06993237 0,11546623 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,06993237 0,1153834 ! protein export from nucleus GO:0006611 24 16 0,000 0,06993237 0,11530069 ! negative regulation of immune response GO:0050777 28 16 0,000 0,06993237 0,11521809 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,06993237 0,11513562 ! DNA replication initiation GO:0006270 25 16 0,000 0,06993237 0,11505326 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,06993237 0,11497102 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,06993237 0,1148889 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,06993237 0,11480689 ! oogenesis GO:0048477 23 16 0,000 0,06993237 0,11472501 ! neural crest cell migration GO:0001755 24 16 0,000 0,06993237 0,11464323 ! G1 phase GO:0051318 27 16 0,000 0,06993237 0,11456158 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,06993237 0,11448004 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,06993237 0,11439862 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,06993237 0,11431731 ! steroid catabolic process GO:0006706 22 16 0,000 0,06993237 0,11423612 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,06993237 0,11415504 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,06993237 0,11407408 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,06993237 0,11399324 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,06993237 0,11391251 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,06993237 0,11383189 ! sperm-egg recognition GO:0035036 16 16 0,000 0,06993237 0,11375138 GO:0007339|binding of sperm to zona pellucida, ! nerve development GO:0021675 18 16 0,000 0,06993237 0,11367099 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,06993237 0,11359072 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,06993237 0,11351056 ! in utero embryonic development GO:0001701 147 96 1,000 0,07003801 0,11360185 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 0,07003801 0,11352179 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,07003801 0,11344185 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,07130917 0,11541948 ! extracellular structure organization GO:0043062 156 99 1,000 0,07387404 0,11948685 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,07413914 0,11983135 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,07413914 0,1197472 ! negative regulation of defense response GO:0031348 19 17 0,000 0,07413914 0,11966317 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,07413914 0,11957925 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,07413914 0,11949546 ! glycerol metabolic process GO:0006071 20 17 0,000 0,07413914 0,11941178 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,07413914 0,11932821 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,07413914 0,11924477 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,07413914 0,11916144 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,07413914 0,11907822 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,07413914 0,11899513 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,07413914 0,11891214 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,07413914 0,11882928 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,07413914 0,11874653 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,07413914 0,11866389 ! retinoid metabolic process GO:0001523 22 17 0,000 0,07413914 0,11858137 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,07413914 0,11849897 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,07413914 0,11841668 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,07413914 0,1183345 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,07413914 0,11825244 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,07413914 0,11817049 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,07413914 0,11808865 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,07413914 0,11800693 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,07413914 0,11792532 ! membrane budding GO:0006900 29 17 0,000 0,07413914 0,11784383 ! heme metabolic process GO:0042168 27 17 0,000 0,07413914 0,11776244 ! actin filament bundle formation GO:0051017 26 17 0,000 0,07413914 0,11768117 ! neuromuscular junction development GO:0007528 23 17 0,000 0,07413914 0,11760001 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,07413914 0,11751896 ! body fluid secretion GO:0007589 27 17 0,000 0,07413914 0,11743803 ! stem cell differentiation GO:0048863 36 17 0,000 0,07413914 0,1173572 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,07413914 0,11727649 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,07413914 0,11719589 ! sensory perception of pain GO:0019233 23 17 0,000 0,07413914 0,1171154 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,07413914 0,11703501 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,07413914 0,11695474 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,07413914 0,11687458 ! synaptogenesis GO:0007416 24 17 0,000 0,07413914 0,11679453 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,07413914 0,11671459 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,07413914 0,11663476 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,07413914 0,11655503 ! cell-cell junction organization GO:0045216 25 17 0,000 0,07413914 0,11647542 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,07413914 0,11639591 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,07413914 0,11631652 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,07413914 0,11623723 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,07413914 0,11615805 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,07413914 0,11607898 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,07413914 0,11600001 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,07516758 0,11752918 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,07516758 0,11744934 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,07832711 0,12230303 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,07832711 0,12222006 ! positive regulation of translation GO:0045727 28 18 0,000 0,07832711 0,12213719 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,07832711 0,12205445 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,07832711 0,12197181 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,07832711 0,12188928 ! cAMP metabolic process GO:0046058 33 18 0,000 0,07832711 0,12180687 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,07832711 0,12172457 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,07832711 0,12164238 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,07832711 0,1215603 ! axis specification GO:0009798 26 18 0,000 0,07832711 0,12147833 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,07832711 0,12139647 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,07832711 0,12131472 ! pancreas development GO:0031016 26 18 0,000 0,07832711 0,12123308 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,07832711 0,12115155 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,07832711 0,12107014 ! glutamine metabolic process GO:0006541 23 18 0,000 0,07832711 0,12098883 ! response to retinoic acid GO:0032526 25 18 0,000 0,07832711 0,12090762 ! pigmentation during development GO:0048066 31 18 0,000 0,07832711 0,12082653 ! central nervous system neuron development GO:0021954 30 18 0,000 0,07832711 0,12074555 ! fucose metabolic process GO:0006004 26 18 0,000 0,07832711 0,12066468 ! response to fungus GO:0009620 19 18 0,000 0,07832711 0,12058391 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,07832711 0,12050325 ! heart process GO:0003015 27 18 0,000 0,07832711 0,1204227 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,07832711 0,12034226 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,07832711 0,12026192 ! visual learning GO:0008542 35 18 0,000 0,07832711 0,1201817 ! somitogenesis GO:0001756 24 18 0,000 0,07832711 0,12010157 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,07832711 0,12002156 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,07832711 0,11994165 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,07832711 0,11986185 ! vitamin transport GO:0051180 24 18 0,000 0,07832711 0,11978216 ! hormone transport GO:0009914 27 18 0,000 0,07832711 0,11970257 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,07832711 0,11962308 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,07832711 0,1195437 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,07832711 0,11946443 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,07832711 0,11938526 ! cell-cell recognition GO:0009988 20 18 0,000 0,07832711 0,1193062 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,07832711 0,11922724 ! regulation of glucose import GO:0046324 21 18 0,000 0,07832711 0,11914839 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,07832711 0,11906964 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,07832711 0,11899099 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,07832711 0,11891245 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,07832711 0,11883401 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,08249639 0,12507692 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,08249639 0,12499452 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,08249639 0,12491224 ! positive regulation of ossification GO:0045778 30 19 0,000 0,08249639 0,12483006 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,08249639 0,12474799 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,08249639 0,12466602 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,08249639 0,12458417 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,08249639 0,12450242 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,08249639 0,12442078 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,08249639 0,12433924 ! regeneration GO:0031099 32 19 0,000 0,08249639 0,12425782 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,08249639 0,1241765 ! response to alkaloid GO:0043279 32 19 0,000 0,08249639 0,12409528 ! sensory perception of taste GO:0050909 23 19 0,000 0,08249639 0,12401417 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,08249639 0,12393317 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,08249639 0,12385228 ! smooth muscle contraction GO:0006939 36 19 0,000 0,08249639 0,12377148 ! peroxisome organization GO:0007031 29 19 0,000 0,08249639 0,1236908 ! digestive system process GO:0022600 30 19 0,000 0,08249639 0,12361022 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,08249639 0,12352974 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,08249639 0,12344937 ! response to vitamin A GO:0033189 26 19 0,000 0,08249639 0,12336911 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,08249639 0,12328894 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,08249639 0,12320889 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,08249639 0,12312893 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,08249639 0,12304908 ! sex determination GO:0007530 29 19 0,000 0,08249639 0,12296934 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,08249639 0,12288969 ! plasma membrane fusion GO:0045026 23 19 0,000 0,08249639 0,12281015 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,08249639 0,12273072 ! cytolysis GO:0019835 20 19 0,000 0,08249639 0,12265138 ! renal system process GO:0003014 35 19 0,000 0,08249639 0,12257215 ! vasodilation GO:0042311 33 19 0,000 0,08249639 0,12249302 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,08249639 0,12241399 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,08249639 0,12233506 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,08249639 0,12225624 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,08249639 0,12217752 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,08249639 0,1220989 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,08249639 0,12202038 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,08249639 0,12194196 ! sarcomere organization GO:0045214 23 19 0,000 0,08249639 0,12186364 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,08249639 0,12178542 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,08249639 0,1217073 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,08249639 0,12162929 GO:0043450|alkene biosynthetic process, ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,08249639 0,12155137 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,08249639 0,12147355 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,08249639 0,12139583 ! protein stabilization GO:0050821 26 19 0,000 0,08249639 0,12131821 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,08664703 0,12734069 ! iron ion transport GO:0006826 37 20 0,000 0,08664703 0,12725937 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,08664703 0,12717816 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,08664703 0,12709705 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,08664703 0,12701605 ! response to vitamin GO:0033273 29 20 0,000 0,08664703 0,12693515 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,08664703 0,12685435 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,08664703 0,12677365 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,08664703 0,12669306 ! spinal cord development GO:0021510 31 20 0,000 0,08664703 0,12661257 ! response to ethanol GO:0045471 37 20 0,000 0,08664703 0,12653218 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,08664703 0,12645189 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,08664703 0,1263717 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,08664703 0,12629162 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,08664703 0,12621164 ! chromosome condensation GO:0030261 31 20 0,000 0,08664703 0,12613176 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,08664703 0,12605198 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,08664703 0,1259723 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,08664703 0,12589272 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,08664703 0,12581324 ! pallium development GO:0021543 38 20 0,000 0,08664703 0,12573387 ! DNA modification GO:0006304 28 20 0,000 0,08664703 0,12565459 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,08664703 0,12557541 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,08664703 0,12549633 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,08664703 0,12541736 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,08664703 0,12533848 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,08664703 0,1252597 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,08664703 0,12518102 ! collagen catabolic process GO:0030574 25 20 0,000 0,08664703 0,12510243 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,08664703 0,12502395 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,08664703 0,12494557 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,08664703 0,12486728 ! alditol metabolic process GO:0019400 24 20 0,000 0,08664703 0,12478909 ! actin filament-based movement GO:0030048 34 20 0,000 0,08664703 0,124711 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,09077914 0,13057663 ! regulation of cell killing GO:0031341 34 21 0,000 0,09077914 0,13049502 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,09077914 0,13041351 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,09077914 0,1303321 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,09077914 0,1302508 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,09077914 0,13016959 GO:0009799|determination of symmetry, ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,09077914 0,13008849 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,09077914 0,13000749 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,09077914 0,12992659 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,09077914 0,12984579 ! protein amino acid acylation GO:0043543 37 21 0,000 0,09077914 0,12976509 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,09077914 0,12968449 ! vesicle docking GO:0048278 27 21 0,000 0,09077914 0,12960399 ! phototransduction GO:0007602 25 21 0,000 0,09077914 0,12952359 ! dendrite development GO:0016358 35 21 0,000 0,09077914 0,12944329 ! visual behavior GO:0007632 39 21 0,000 0,09077914 0,12936309 ! ovarian follicle development GO:0001541 30 21 0,000 0,09077914 0,12928299 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,09077914 0,12920299 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,09077914 0,12912309 ! autophagy GO:0006914 28 21 0,000 0,09077914 0,12904328 ! cell aging GO:0007569 32 21 0,000 0,09077914 0,12896358 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,09077914 0,12888397 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,09077914 0,12880446 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,09077914 0,12872505 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,09077914 0,12864574 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,09077914 0,12856652 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,09077914 0,1284874 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,09077914 0,12840838 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,09077914 0,12832946 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,09077914 0,12825063 ! fatty acid transport GO:0015908 30 21 0,000 0,09077914 0,1281719 ! platelet activation GO:0030168 28 21 0,000 0,09077914 0,12809327 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,09077914 0,12801473 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,09077914 0,12793629 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,09077914 0,12785795 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,09077914 0,1277797 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,09077914 0,12770155 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,09077914 0,12762349 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,09077914 0,12754553 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,09077914 0,12746766 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,09077914 0,12738989 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,09077914 0,12731221 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,09077914 0,12723463 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,09077914 0,12715714 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,09077914 0,12707975 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,09489279 0,13275756 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,09489279 0,13267685 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,09489279 0,13259625 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,09489279 0,13251574 ! viral genome replication GO:0019079 29 22 0,000 0,09489279 0,13243533 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,09489279 0,13235502 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,09489279 0,1322748 ! molting cycle process GO:0022404 40 22 0,000 0,09489279 0,13219468 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,09489279 0,13211466 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,09489279 0,13203474 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,09489279 0,13195491 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,09489279 0,13187518 ! vasculogenesis GO:0001570 33 22 0,000 0,09489279 0,13179555 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,09489279 0,13171601 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,09489279 0,13163656 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,09489279 0,13155722 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,09489279 0,13147797 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,09489279 0,13139881 ! lysosome organization GO:0007040 37 22 0,000 0,09489279 0,13131975 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,09489279 0,13124078 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,09489279 0,13116191 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,09489279 0,13108314 ! regulation of behavior GO:0050795 38 22 0,000 0,09489279 0,13100446 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,09489279 0,13092587 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,09489279 0,13084738 ! membrane depolarization GO:0051899 35 22 0,000 0,09489279 0,13076898 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,09489279 0,13069067 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,09489279 0,13061246 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,09489279 0,13053434 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,09489279 0,13045632 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,09489279 0,13037839 ! blastocyst development GO:0001824 37 22 0,000 0,09489279 0,13030055 ! neural tube closure GO:0001843 33 22 0,000 0,09489279 0,13022281 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,09489279 0,13014515 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,09898807 0,1356809 ! neuron fate commitment GO:0048663 32 23 0,000 0,09898807 0,13560009 ! embryonic pattern specification GO:0009880 31 23 0,000 0,09898807 0,13551938 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,09898807 0,13543876 ! myelination GO:0042552 35 23 0,000 0,09898807 0,13535824 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,09898807 0,13527781 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,09898807 0,13519748 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,09898807 0,13511724 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,09898807 0,1350371 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,09898807 0,13495706 ! vesicle targeting GO:0006903 32 23 0,000 0,09898807 0,1348771 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,09898807 0,13479725 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,09898807 0,13471749 ! osteoblast differentiation GO:0001649 40 23 0,000 0,09898807 0,13463782 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,09898807 0,13455825 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,09898807 0,13447877 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,09898807 0,13439938 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,09898807 0,13432009 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,09898807 0,13424089 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,09898807 0,13416179 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,09898807 0,13408278 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,09898807 0,13400386 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,09898807 0,13392503 ! pentose metabolic process GO:0019321 31 23 0,000 0,09898807 0,1338463 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,09898807 0,13376766 ! spermatid development GO:0007286 33 23 0,000 0,09898807 0,13368911 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,09898807 0,13361065 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,09898807 0,13353229 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,09898807 0,13345402 ! telomere organization GO:0032200 32 23 0,000 0,09898807 0,13337584 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,09898807 0,13329775 ! regulation of amine transport GO:0051952 38 23 0,000 0,09898807 0,13321975 ! liver development GO:0001889 40 23 0,000 0,09898807 0,13314184 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,10306504 0,13854448 ! initiation of viral infection GO:0019059 42 24 0,000 0,10306504 0,13846355 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,10306504 0,13838272 ! superoxide metabolic process GO:0006801 32 24 0,000 0,10306504 0,13830198 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,10306504 0,13822134 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,10306504 0,13814079 ! fat cell differentiation GO:0045444 37 24 0,000 0,10306504 0,13806034 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,10306504 0,13797998 ! sperm motility GO:0030317 27 24 0,000 0,10306504 0,13789971 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,10306504 0,13781953 ! vacuole organization GO:0007033 39 24 0,000 0,10306504 0,13773945 ! receptor metabolic process GO:0043112 37 24 0,000 0,10306504 0,13765947 ! neural crest cell development GO:0014032 39 24 0,000 0,10306504 0,13757957 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,10306504 0,13749977 ! primary neural tube formation GO:0014020 35 24 0,000 0,10306504 0,13742006 ! negative regulation of cell development GO:0010721 56 24 0,000 0,10306504 0,13734044 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,10306504 0,13726091 ! base-excision repair GO:0006284 31 24 0,000 0,10306504 0,13718148 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,10306504 0,13710214 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,10306504 0,13702289 ! glutathione metabolic process GO:0006749 29 24 0,000 0,10306504 0,13694373 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,10306504 0,13686467 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,10306504 0,13678569 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,10712381 0,1420904 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,10712381 0,1420085 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,10712381 0,1419267 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,10712381 0,14184499 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,10712381 0,14176338 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,10712381 0,14168186 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,10712381 0,14160043 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,10712381 0,1415191 ! peptide transport GO:0015833 43 25 0,000 0,10712381 0,14143786 ! male gonad development GO:0008584 33 25 0,000 0,10712381 0,14135671 ! iron ion homeostasis GO:0055072 39 25 0,000 0,10712381 0,14127566 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,10712381 0,1411947 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,10712381 0,14111383 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,10712381 0,14103306 ! phospholipid transport GO:0015914 35 25 0,000 0,10712381 0,14095238 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,10712381 0,14087179 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,10712381 0,14079129 ! detection of light stimulus GO:0009583 30 25 0,000 0,10712381 0,14071088 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,10712381 0,14063057 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,10712381 0,14055034 ! leukocyte proliferation GO:0070661 39 25 0,000 0,10712381 0,14047021 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,10712381 0,14039017 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,11116443 0,14560262 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,11116443 0,14551975 ! regulation of pH GO:0006885 36 26 0,000 0,11116443 0,14543697 ! circadian rhythm GO:0007623 42 26 0,000 0,11116443 0,14535429 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,11116443 0,1452717 ! post-embryonic development GO:0009791 42 26 0,000 0,11116443 0,14518921 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,11116443 0,14510681 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,11116443 0,1450245 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,11116443 0,14494229 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,11116443 0,14486017 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,11116443 0,14477814 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,11116443 0,1446962 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,11116443 0,14461436 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,11116443 0,14453261 ! regulation of coagulation GO:0050818 39 26 0,000 0,11116443 0,14445096 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,115187 0,14959351 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,115187 0,14950909 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,115187 0,14942476 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,115187 0,14934053 ! membrane docking GO:0022406 39 27 0,000 0,115187 0,1492564 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,115187 0,14917236 ! catechol metabolic process GO:0009712 43 27 0,000 0,115187 0,14908841 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,115187 0,14900456 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,115187 0,1489208 ! myofibril assembly GO:0030239 36 27 0,000 0,115187 0,14883714 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,115187 0,14875357 ! response to ionizing radiation GO:0010212 47 27 0,000 0,115187 0,14867009 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,115187 0,14858671 ! natural killer cell activation GO:0030101 35 27 0,000 0,115187 0,14850342 ! lipid oxidation GO:0034440 38 27 0,000 0,115187 0,14842023 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,115187 0,14833713 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,115187 0,14825412 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,115187 0,1481712 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,115187 0,14808838 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,115187 0,14800565 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,115187 0,14792301 ! gene silencing GO:0016458 41 27 0,000 0,115187 0,14784046 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,1191916 0,15289497 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,1191916 0,15280974 ! phenol metabolic process GO:0018958 44 28 0,000 0,1191916 0,15272461 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,1191916 0,15263958 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,1191916 0,15255464 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,1191916 0,15246979 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,1191916 0,15238504 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,1191916 0,15230038 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,1191916 0,15221581 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,1191916 0,15213134 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,1191916 0,15204697 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,1191916 0,15196268 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,1191916 0,15187849 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,1191916 0,1517944 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,1191916 0,15171039 ! mesoderm formation GO:0001707 46 28 0,000 0,1191916 0,15162648 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,1191916 0,15154266 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,1191916 0,15145894 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,1191916 0,15137531 ! ensheathment of neurons GO:0007272 43 28 0,000 0,1191916 0,15129177 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,1191916 0,15120832 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,1191916 0,15112496 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,1191916 0,1510417 ! neural tube formation GO:0001841 41 28 0,000 0,1191916 0,15095852 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,1191916 0,15087544 ! regulation of B cell activation GO:0050864 42 28 0,000 0,1191916 0,15079245 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,1231783 0,15575046 ! regulation of innate immune response GO:0045088 38 29 0,000 0,1231783 0,15566488 ! ovulation cycle process GO:0022602 41 29 0,000 0,1231783 0,1555794 ! protein targeting to membrane GO:0006612 53 29 0,000 0,1231783 0,15549401 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,1231783 0,15540872 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,1231783 0,15532351 ! muscle cell development GO:0055001 38 29 0,000 0,1231783 0,15523841 ! formation of primary germ layer GO:0001704 48 29 0,000 0,1231783 0,15515339 ! telencephalon development GO:0021537 52 29 0,000 0,1231783 0,15506847 ! eye morphogenesis GO:0048592 51 29 0,000 0,1231783 0,15498364 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,1231783 0,1548989 ! tissue homeostasis GO:0001894 42 29 0,000 0,1231783 0,15481426 GO:0048871|multicellular organismal homeostasis, ! collagen metabolic process GO:0032963 40 30 0,000 0,12714718 0,15971519 ! organic anion transport GO:0015711 51 30 0,000 0,12714718 0,15962801 ! cholesterol transport GO:0030301 46 30 0,000 0,12714718 0,15954093 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,12714718 0,15945394 ! spliceosome assembly GO:0000245 49 30 0,000 0,12714718 0,15936704 ! spindle organization GO:0007051 37 30 0,000 0,12714718 0,15928024 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,12714718 0,15919353 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,12714718 0,15910692 ! ceramide metabolic process GO:0006672 43 30 0,000 0,12714718 0,1590204 ! ovulation cycle GO:0042698 43 30 0,000 0,12714718 0,15893398 ! hindbrain development GO:0030902 45 30 0,000 0,12714718 0,15884765 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,12714718 0,15876141 ! adult locomotory behavior GO:0008344 47 30 0,000 0,12714718 0,15867527 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,12714718 0,15858922 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,12714718 0,15850326 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,12714718 0,1584174 ! response to heat GO:0009408 41 30 0,000 0,12714718 0,15833163 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,12714718 0,15824595 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,12714718 0,15816037 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,13109833 0,16298711 ! negative regulation of secretion GO:0051048 49 31 0,000 0,13109833 0,16289906 ! mammary gland development GO:0030879 57 31 0,000 0,13109833 0,1628111 ! glial cell differentiation GO:0010001 55 31 0,000 0,13109833 0,16272323 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,13109833 0,16263547 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,13109833 0,16254779 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,13109833 0,16246021 ! odontogenesis GO:0042476 50 31 0,000 0,13109833 0,16237273 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,13109833 0,16228534 ! segmentation GO:0035282 41 31 0,000 0,13109833 0,16219804 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,13109833 0,16211083 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,13109833 0,16202373 ! metanephros development GO:0001656 58 31 0,000 0,13109833 0,16193671 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,13109833 0,16184979 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,13109833 0,16176296 ! cell fate specification GO:0001708 37 31 0,000 0,13109833 0,16167622 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,13109833 0,16158958 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,13109833 0,16150303 ! RNA modification GO:0009451 40 31 0,000 0,13109833 0,16141657 ! regulation of muscle development GO:0048634 48 32 0,000 0,13503181 0,16617077 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,13503181 0,16608191 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,13503181 0,16599314 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,13503181 0,16590447 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,13503181 0,16581589 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,13503181 0,16572741 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,13503181 0,16563902 ! peripheral nervous system development GO:0007422 53 32 0,000 0,13503181 0,16555073 ! regulation of protein stability GO:0031647 48 32 0,000 0,13503181 0,16546253 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,13503181 0,16537442 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,13503181 0,16528641 ! cytokine production GO:0001816 44 32 0,000 0,13503181 0,16519849 ! vesicle localization GO:0051648 47 32 0,000 0,13503181 0,16511067 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,13894771 0,16980858 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,13894771 0,1697184 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,13894771 0,16962831 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,13894771 0,16953832 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,13894771 0,16944843 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,13894771 0,16935863 ! sister chromatid segregation GO:0000819 46 33 0,000 0,13894771 0,16926893 ! ear morphogenesis GO:0042471 42 33 0,000 0,13894771 0,16917932 ! actomyosin structure organization GO:0031032 43 33 0,000 0,13894771 0,16908981 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,13894771 0,16900039 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,13894771 0,16891107 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,13894771 0,16882184 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,13894771 0,1687327 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,13894771 0,16864366 ! female gonad development GO:0008585 49 33 0,000 0,13894771 0,16855472 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,13894771 0,16846586 ! positive regulation of cell development GO:0010720 54 33 0,000 0,13894771 0,1683771 ! lipid homeostasis GO:0055088 55 33 0,000 0,13894771 0,16828844 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,13894771 0,16819986 ! regulation of proteolysis GO:0030162 50 33 0,000 0,13894771 0,16811138 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,13894771 0,168023 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,13894771 0,1679347 ! cytokinesis GO:0000910 52 33 0,000 0,13894771 0,1678465 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,13894771 0,16775839 ! mRNA catabolic process GO:0006402 48 34 0,000 0,14284611 0,17237463 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,14284611 0,17228424 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,14284611 0,17219395 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,14284611 0,17210375 ! feeding behavior GO:0007631 45 34 0,000 0,14284611 0,17201364 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,14284611 0,17192363 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,14284611 0,17183371 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,14284611 0,17174389 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,14284611 0,17165416 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,14284611 0,17156452 ! neuron migration GO:0001764 46 34 0,000 0,14284611 0,17147498 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,14284611 0,17138553 ! female gamete generation GO:0007292 43 34 0,000 0,14284611 0,17129617 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,14284611 0,17120691 ! polyol metabolic process GO:0019751 44 34 0,000 0,14284611 0,17111774 ! aerobic respiration GO:0009060 47 34 0,000 0,14284611 0,17102866 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,14284611 0,17093967 ! embryonic organ development GO:0048568 45 34 0,000 0,14284611 0,17085078 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,14284611 0,17076198 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,14672708 0,17531028 ! Notch signaling pathway GO:0007219 56 35 0,000 0,14672708 0,17521925 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,14672708 0,17512833 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,14672708 0,17503749 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,14672708 0,17494675 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,14672708 0,17485611 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,14672708 0,17476555 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,14672708 0,1746751 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,14672708 0,17458473 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,14672708 0,17449446 ! glycogen metabolic process GO:0005977 48 35 0,000 0,14672708 0,17440428 ! pigment metabolic process GO:0042440 61 35 0,000 0,14672708 0,1743142 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,1505907 0,17881188 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,1505907 0,17871961 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,1505907 0,17862744 ! negative regulation of binding GO:0051100 58 36 0,000 0,1505907 0,17853536 ! organic ether metabolic process GO:0018904 46 36 0,000 0,1505907 0,17844338 ! tissue remodeling GO:0048771 62 36 0,000 0,1505907 0,1783515 ! neural tube development GO:0021915 50 36 0,000 0,1505907 0,17825971 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,1505907 0,17816801 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,1505907 0,1780764 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,1505907 0,1779849 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,1505907 0,17789348 ! glucan metabolic process GO:0044042 49 36 0,000 0,1505907 0,17780216 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,15443704 0,18224997 ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,15443704 0,18215651 ! learning GO:0007612 67 37 0,000 0,15443704 0,18206315 ! ion transmembrane transport GO:0034220 56 37 0,000 0,15443704 0,18196988 ! regulation of protein secretion GO:0050708 51 37 0,000 0,15443704 0,1818767 ! amino acid activation GO:0043038 52 37 0,000 0,15443704 0,18178362 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,15443704 0,18169064 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,15826619 0,18610033 ! gliogenesis GO:0042063 71 38 0,000 0,15826619 0,18600523 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,15826619 0,18591023 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,15826619 0,18581533 ! phagocytosis GO:0006909 60 38 0,000 0,15826619 0,18572053 ! mesenchymal cell development GO:0014031 64 38 0,000 0,15826619 0,18562582 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,15826619 0,18553121 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,16207822 0,18990316 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,16207822 0,18980647 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,16207822 0,18970987 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,16207822 0,18961338 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,16207822 0,18951698 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,16207822 0,18942068 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,16207822 0,18932448 ! male sex differentiation GO:0046661 53 39 0,000 0,16207822 0,18922837 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,16207822 0,18913237 ! chromatin remodeling GO:0006338 68 39 0,000 0,16207822 0,18903646 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,16207822 0,18894065 ! JNK cascade GO:0007254 54 39 0,000 0,16207822 0,18884493 ! developmental growth GO:0048589 62 39 0,000 0,16207822 0,18874932 ! synapse organization GO:0050808 55 39 0,000 0,16207822 0,18865379 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,1658732 0,19297337 ! regulation of tube size GO:0035150 60 40 0,000 0,1658732 0,19287581 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,1658732 0,19277835 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,1658732 0,19268098 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,1658732 0,19258372 ! peptide metabolic process GO:0006518 56 40 0,000 0,1658732 0,19248655 ! inner ear development GO:0048839 57 40 0,000 0,1658732 0,19238949 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,1658732 0,19229252 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,1658732 0,19219564 ! double-strand break repair GO:0006302 67 40 0,000 0,1658732 0,19209887 ! B cell differentiation GO:0030183 62 40 0,000 0,1658732 0,19200219 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,1658732 0,19190561 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,1658732 0,19180913 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,1696512 0,19607928 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,1696512 0,1959808 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,1696512 0,19588241 ! glucose transport GO:0015758 52 41 0,000 0,1696512 0,19578413 ! endosome transport GO:0016197 71 41 0,000 0,1696512 0,19568594 ! striated muscle contraction GO:0006941 62 41 0,000 0,1696512 0,19558785 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,1696512 0,19548986 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,1696512 0,19539197 ! biopolymer methylation GO:0043414 62 41 0,000 0,1696512 0,19529418 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,1696512 0,19519648 ! mitochondrial transport GO:0006839 60 42 0,000 0,17341232 0,19942416 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,17341232 0,1993245 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,17341232 0,19922494 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,17341232 0,19912547 ! cellular component disassembly GO:0022411 64 42 0,000 0,17341232 0,19902611 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,17341232 0,19892685 ! hexose transport GO:0008645 54 42 0,000 0,17341232 0,19882768 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,17341232 0,19872861 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,17341232 0,19862964 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,17341232 0,19853077 ! excretion GO:0007588 63 42 0,000 0,17341232 0,198432 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,17341232 0,19833333 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,17341232 0,19823475 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,17341232 0,19813628 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 0,000 0,17715661 0,2023139 ! leukocyte migration GO:0050900 60 43 0,000 0,17715661 0,2022135 ! neuromuscular process GO:0050905 79 43 0,000 0,17715661 0,20211319 ! activation of caspase activity GO:0006919 65 43 0,000 0,17715661 0,20201299 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,17715661 0,20191288 ! tRNA processing GO:0008033 49 43 0,000 0,17715661 0,20181287 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,17715661 0,20171297 ! vesicle organization GO:0016050 79 43 0,000 0,17715661 0,20161316 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,17715661 0,20151345 ! methylation GO:0032259 64 43 0,000 0,17715661 0,20141384 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,18088415 0,20555017 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,18088415 0,20544866 ! glycolysis GO:0006096 53 44 0,000 0,18088415 0,20534726 ! regulation of action potential GO:0001508 71 44 0,000 0,18088415 0,20524595 ! regulation of ion transport GO:0043269 57 44 0,000 0,18088415 0,20514475 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,18088415 0,20504364 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,18088415 0,20494263 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,18088415 0,20484173 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,18088415 0,20474092 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,18088415 0,20464021 ! positive regulation of cell cycle GO:0045787 77 45 0,000 0,18459502 0,20873576 ! RNA catabolic process GO:0006401 64 45 0,000 0,18459502 0,20863319 ! positive regulation of defense response GO:0031349 59 45 0,000 0,18459502 0,20853072 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,18459502 0,20842835 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,18459502 0,20832608 ! cell recognition GO:0008037 58 45 0,000 0,18459502 0,20822391 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,18459502 0,20812184 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,18828929 0,21218293 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,18828929 0,21207902 ! cell redox homeostasis GO:0045454 63 46 0,000 0,18828929 0,21197522 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,18828929 0,21187151 ! regulation of ossification GO:0030278 71 46 0,000 0,18828929 0,21176791 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,18828929 0,2116644 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,19196703 0,2156933 ! viral infectious cycle GO:0019058 71 47 0,000 0,19196703 0,21558798 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,19196703 0,21548276 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,19196703 0,21537765 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,19196703 0,21527264 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,19196703 0,21516773 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,19196703 0,21506292 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,19196703 0,21495822 ! chloride transport GO:0006821 67 48 0,000 0,19562832 0,21895141 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,19562832 0,21884492 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,19562832 0,21873853 ! response to temperature stimulus GO:0009266 62 48 0,000 0,19562832 0,21863224 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,19562832 0,21852606 ! gastrulation GO:0007369 73 48 0,000 0,19562832 0,21841997 ! heart morphogenesis GO:0003007 65 48 0,000 0,19562832 0,218314 ! regulation of DNA replication GO:0006275 75 48 0,000 0,19562832 0,21820812 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,19562832 0,21810235 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,19562832 0,21799668 ! nuclear export GO:0051168 69 48 0,000 0,19562832 0,21789111 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,19562832 0,21778565 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,19562832 0,21768028 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,19927324 0,22162884 ! sensory perception of smell GO:0007608 61 49 0,000 0,19927324 0,22152172 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,19927324 0,22141471 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,19927324 0,22130779 ! RNA elongation GO:0006354 62 49 0,000 0,19927324 0,22120098 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,19927324 0,22109428 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,19927324 0,22098768 ! germ cell development GO:0007281 68 49 0,000 0,19927324 0,22088118 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,19927324 0,22077478 ! cartilage development GO:0051216 70 49 0,000 0,19927324 0,22066848 ! ear development GO:0043583 72 50 0,000 0,20290184 0,22457855 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,20290184 0,22447053 ! membrane fusion GO:0006944 80 50 0,000 0,20290184 0,22436261 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,20290184 0,22425479 ! lipid modification GO:0030258 73 50 0,000 0,20290184 0,22414708 ! positive regulation of growth GO:0045927 67 50 0,000 0,20290184 0,22403947 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,20290184 0,22393197 ! proton transport GO:0015992 75 50 0,000 0,20290184 0,22382457 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,20290184 0,22371727 ! positive regulation of secretion GO:0051047 71 51 0,000 0,2065142 0,22759112 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 0,000 0,2065142 0,22748212 ! hydrogen transport GO:0006818 77 51 0,000 0,2065142 0,22737322 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,2065142 0,22726443 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,2065142 0,22715575 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,2065142 0,22704716 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,2065142 0,22693868 ! adult behavior GO:0030534 80 51 0,000 0,2065142 0,22683031 ! transition metal ion transport GO:0000041 74 52 0,000 0,2101104 0,23067013 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,2101104 0,23056008 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,2101104 0,23045013 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,2101104 0,23034029 ! establishment of organelle localization GO:0051656 85 52 0,000 0,2101104 0,23023055 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,21369051 0,23404199 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,21369051 0,23393059 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,21369051 0,2338193 ! single fertilization GO:0007338 59 53 0,000 0,21369051 0,23370812 ! amino acid transport GO:0006865 84 54 0,000 0,2172546 0,23749314 ! regulation of mitosis GO:0007088 84 54 0,000 0,2172546 0,23738032 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,2172546 0,2372676 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,2172546 0,23715499 ! DNA catabolic process GO:0006308 67 54 0,000 0,2172546 0,23704249 ! detection of external stimulus GO:0009581 66 54 0,000 0,2172546 0,2369301 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,2172546 0,23681781 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,2172546 0,23670562 ! exocytosis GO:0006887 74 55 0,000 0,22080273 0,24045752 ! mesoderm development GO:0007498 76 55 0,000 0,22080273 0,24034372 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,22080273 0,24023003 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,22433498 0,24395767 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,22433498 0,24384237 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,22433498 0,24372719 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,22785143 0,24743073 ! carbohydrate transport GO:0008643 74 57 0,000 0,22785143 0,24731396 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,22785143 0,2471973 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,22785143 0,24708076 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,22785143 0,24696432 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,22785143 0,24684799 ! camera-type eye development GO:0043010 88 57 0,000 0,22785143 0,24673177 ! secondary metabolic process GO:0019748 84 57 0,000 0,22785143 0,24661566 ! gonad development GO:0008406 79 57 0,000 0,22785143 0,24649966 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,23135213 0,2501692 ! viral reproductive process GO:0022415 87 58 0,000 0,23135213 0,25005164 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,23135213 0,24993419 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,23483716 0,25358003 ! activation of MAPK activity GO:0000187 84 59 0,000 0,23483716 0,25346104 ! lung development GO:0030324 94 59 0,000 0,23483716 0,25334215 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,23483716 0,25322338 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,23483716 0,25310472 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,23830659 0,25672373 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,23830659 0,25660354 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,23830659 0,25648346 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,23830659 0,2563635 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,23830659 0,25624365 ! regulation of heart contraction GO:0008016 91 60 0,000 0,23830659 0,25612391 ! fertilization GO:0009566 68 60 0,000 0,23830659 0,25600428 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,23830659 0,25588476 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,24176049 0,25947229 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,24176049 0,25935127 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,24176049 0,25923036 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,24176049 0,25910956 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,24176049 0,25898888 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,24176049 0,2588683 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,24176049 0,25874784 ! amine catabolic process GO:0009310 90 62 0,000 0,24519892 0,26230582 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,24519892 0,26218387 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,24519892 0,26206204 ! respiratory tube development GO:0030323 99 62 0,000 0,24519892 0,26194032 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,24519892 0,26181871 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,24862195 0,26535058 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,24862195 0,2652275 ! viral reproduction GO:0016032 92 63 0,000 0,24862195 0,26510454 ! regulation of lipase activity GO:0060191 109 63 0,000 0,24862195 0,26498169 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,25202966 0,26848922 ! negative regulation of cell size GO:0045792 108 64 0,000 0,25202966 0,26836492 ! appendage morphogenesis GO:0035107 93 64 0,000 0,25202966 0,26824073 GO:0035108|limb morphogenesis, ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,25202966 0,26811666 ! hexose catabolic process GO:0019320 82 64 0,000 0,25202966 0,26799271 ! respiratory system development GO:0060541 100 64 0,000 0,25202966 0,26786886 ! reproductive structure development GO:0048608 90 65 0,000 0,25542211 0,27134912 ! regulation of caspase activity GO:0043281 97 65 0,000 0,25542211 0,27122385 ! appendage development GO:0048736 94 65 0,000 0,25542211 0,27109869 GO:0060173|limb development, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,25542211 0,27097364 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,25542211 0,27084871 ! defense response to bacterium GO:0042742 73 65 0,000 0,25542211 0,2707239 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,25542211 0,2705992 ! antigen processing and presentation GO:0019882 96 66 0,000 0,25879937 0,27405089 ! axon guidance GO:0007411 99 66 0,000 0,25879937 0,27392478 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,25879937 0,27379878 ! regulation of immune effector process GO:0002697 101 66 0,000 0,25879937 0,27367289 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,26216149 0,27710084 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,26216149 0,27697356 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,26550857 0,28038095 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,26550857 0,28025227 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,26550857 0,28012372 ! rhythmic process GO:0048511 105 68 0,000 0,26550857 0,27999528 ! inorganic anion transport GO:0015698 93 68 0,000 0,26550857 0,27986696 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,26884064 0,28324942 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,26884064 0,28311973 ! response to drug GO:0042493 108 69 0,000 0,26884064 0,28299015 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,26884064 0,2828607 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,2721578 0,28621991 ! eye development GO:0001654 111 70 0,000 0,2721578 0,28608909 ! amine transport GO:0015837 101 70 0,000 0,2721578 0,2859584 ! positive regulation of phosphorylation GO:0042327 102 70 0,000 0,2721578 0,28582782 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,2721578 0,28569737 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,27546009 0,28903203 ! muscle cell differentiation GO:0042692 104 71 0,000 0,27546009 0,28890023 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,27546009 0,28876856 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,27546009 0,288637 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,27546009 0,28850556 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,27546009 0,28837424 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 0,000 0,27874759 0,2916831 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 0,000 0,27874759 0,29155046 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,27874759 0,29141794 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,27874759 0,29128553 ! negative regulation of transport GO:0051051 116 73 0,000 0,28202036 0,29457168 ! regulation of blood pressure GO:0008217 107 73 0,000 0,28202036 0,29443796 ! tube morphogenesis GO:0035239 118 73 0,000 0,28202036 0,29430437 ! mitochondrion organization GO:0007005 104 73 0,000 0,28202036 0,2941709 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,28202036 0,29403755 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,28202036 0,29390432 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,28527847 0,29716507 ! response to oxygen levels GO:0070482 137 74 0,000 0,28527847 0,29703055 ! digestion GO:0007586 97 74 0,000 0,28527847 0,29689614 ! protein import into nucleus GO:0006606 118 74 0,000 0,28527847 0,29676186 ! blood coagulation GO:0007596 116 75 0,000 0,28852198 0,30000025 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,28852198 0,29986469 ! response to nutrient GO:0007584 104 75 0,000 0,28852198 0,29972925 ! regulation of ligase activity GO:0051340 114 75 0,000 0,28852198 0,29959393 ! nuclear import GO:0051170 121 75 0,000 0,28852198 0,29945873 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,28852198 0,29932366 ! amine biosynthetic process GO:0009309 97 76 0,000 0,29175095 0,30253706 ! tRNA metabolic process GO:0006399 95 76 0,000 0,29175095 0,30240072 ! response to unfolded protein GO:0006986 99 76 0,000 0,29175095 0,3022645 ! regulation of protein transport GO:0051223 114 76 0,000 0,29175095 0,30212841 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,29496546 0,30531978 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,29496546 0,30518244 ! sex differentiation GO:0007548 105 77 0,000 0,29496546 0,30504521 ! protein ubiquitination GO:0016567 125 77 0,000 0,29496546 0,30490811 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,29496546 0,30477114 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,29496546 0,30463429 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,29816556 0,30780107 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,29816556 0,30766298 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,29816556 0,30752501 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,30135131 0,31067146 ! cellular respiration GO:0045333 107 79 0,000 0,30135131 0,31053227 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,30135131 0,3103932 ! regulation of lyase activity GO:0051339 133 79 0,000 0,30135131 0,31025426 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,30135131 0,31011545 ! chromatin assembly GO:0031497 102 80 0,000 0,30452279 0,31323901 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,30452279 0,31309898 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,30452279 0,31295908 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,30452279 0,31281931 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,30452279 0,31267965 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,30768006 0,31578051 ! hemostasis GO:0007599 125 81 0,000 0,30768006 0,31563967 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,30768006 0,31549894 ! response to protein stimulus GO:0051789 111 81 0,000 0,30768006 0,31535835 ! regulation of neurological system process GO:0031644 122 81 0,000 0,30768006 0,31521788 ! vitamin metabolic process GO:0006766 103 81 0,000 0,30768006 0,31507753 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,31395219 0,32135738 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,31395219 0,32121443 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,31395219 0,3210716 ! regulation of defense response GO:0031347 117 84 0,000 0,31706718 0,32411312 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,31706718 0,32396913 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,31706718 0,32382528 ! sterol metabolic process GO:0016125 120 84 0,000 0,31706718 0,32368154 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,32016821 0,32670226 ! rRNA metabolic process GO:0016072 107 85 0,000 0,32016821 0,32655738 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,32016821 0,32641263 ! transcription initiation GO:0006352 118 85 0,000 0,32016821 0,326268 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,32016821 0,32612351 ! regulation of protein localization GO:0032880 132 85 0,000 0,32016821 0,32597914 ! regulation of membrane potential GO:0042391 128 85 0,000 0,32016821 0,32583491 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,32325534 0,32883117 ! cell cycle arrest GO:0007050 150 86 0,000 0,32325534 0,3286858 ! interphase of mitotic cell cycle GO:0051329 156 86 0,000 0,32325534 0,32854055 ! nucleosome organization GO:0034728 114 87 0,000 0,32632862 0,33151759 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,32632862 0,33137122 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,32632862 0,33122499 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,32632862 0,33107888 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,32632862 0,3309329 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,32938812 0,33388836 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,32938812 0,33374127 ! interphase GO:0051325 159 88 0,000 0,32938812 0,33359431 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,32938812 0,33344748 GO:0016054|organic acid catabolic process, ! regulation of neurogenesis GO:0050767 153 89 0,000 0,3324339 0,33638274 ! reproductive developmental process GO:0003006 127 89 0,000 0,3324339 0,33623482 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,3324339 0,33608702 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,3324339 0,33593936 ! leukocyte differentiation GO:0002521 143 90 0,000 0,33546603 0,33885457 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,33546603 0,33870582 ! hormone metabolic process GO:0042445 121 90 0,000 0,33546603 0,3385572 ! ATP metabolic process GO:0046034 137 91 0,000 0,33848455 0,34145371 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,34148954 0,34433404 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,34148954 0,34418315 ! sulfur metabolic process GO:0006790 118 92 0,000 0,34148954 0,34403239 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,34448105 0,34689422 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,34448105 0,34674241 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,34448105 0,34659073 ! electron transport chain GO:0022900 123 94 0,000 0,34745914 0,3494342 ! response to oxidative stress GO:0006979 141 94 0,000 0,34745914 0,34928147 ! angiogenesis GO:0001525 149 95 0,000 0,35042387 0,35210786 ! carboxylic acid transport GO:0046942 147 95 0,000 0,35042387 0,3519541 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,3533753 0,3547635 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,3533753 0,35460872 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,35631348 0,35740123 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,36215037 0,36309758 ! protein import GO:0017038 156 99 0,000 0,36215037 0,36293937 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,36504919 0,36568516 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,36504919 0,36552596 ! divalent metal ion transport GO:0070838 171 100 0,000 0,36504919 0,3653669 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,36504919 0,36520798 ! protein localization in organelle GO:0033365 161 100 0,000 0,36504919 0,36504919