pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-pos-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/103-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 2,000 3,641E-07 8,895E-04 ! respiratory burst GO:0045730 17 11 2,000 5,92E-06 7,231E-03 ! immunoglobulin mediated immune response GO:0016064 89 50 3,000 2,442E-05 0,01988362 GO:0019724|B cell mediated immunity, ! peptide cross-linking GO:0018149 39 19 2,000 3,409E-05 0,02082224 ! estrogen receptor signaling pathway GO:0030520 45 20 2,000 4,001E-05 0,01954954 ! negative regulation of translation GO:0017148 32 20 2,000 4,001E-05 0,01629128 ! lymphocyte mediated immunity GO:0002449 122 65 3,000 6,906E-05 0,0241008 ! adaptive immune response GO:0002250 126 68 3,000 8,243E-05 0,02517075 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of helicase activity GO:0051096 12 5 1,000 1,104E-04 0,02997284 ! cell adhesion mediated by integrin GO:0033627 10 5 1,000 1,104E-04 0,02697555 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 1,128E-04 0,02504163 ! acute inflammatory response GO:0002526 118 74 3,000 1,147E-04 0,02334502 ! leukocyte mediated immunity GO:0002443 136 75 3,000 1,208E-04 0,02270473 ! translational initiation GO:0006413 66 29 2,000 1,255E-04 0,02189229 ! complement activation, classical pathway GO:0006958 51 30 2,000 1,391E-04 0,02264775 ! positive regulation of actin filament polymerization GO:0030838 11 6 1,000 1,653E-04 0,02523412 ! regulation of collagen metabolic process GO:0010712 10 6 1,000 1,653E-04 0,02374976 ! interaction with symbiont GO:0051702 14 6 1,000 1,653E-04 0,02243033 ! determination of adult lifespan GO:0008340 17 6 1,000 1,653E-04 0,02124979 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 2,000 1,691E-04 0,02065007 ! regulation of helicase activity GO:0051095 16 7 1,000 2,309E-04 0,02685739 ! negative regulation of cellular catabolic process GO:0031330 12 7 1,000 2,309E-04 0,0256366 ! fibril organization GO:0043206 17 7 1,000 2,309E-04 0,02452196 ! regulation of dopamine metabolic process GO:0042053 12 7 1,000 2,309E-04 0,02350021 GO:0042069|regulation of catecholamine metabolic process, ! nucleoside salvage GO:0043174 11 7 1,000 2,309E-04 0,02256021 GO:0006166|purine ribonucleoside salvage, ! negative regulation of DNA recombination GO:0045910 16 7 1,000 2,309E-04 0,0216925 ! wound healing, spreading of epidermal cells GO:0035313 16 7 1,000 2,309E-04 0,02088908 ! regulation of cellular amine metabolic process GO:0033238 13 8 1,000 3,071E-04 0,02679852 ! negative regulation of translational initiation GO:0045947 12 8 1,000 3,071E-04 0,02587443 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 3,071E-04 0,02501195 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 1,000 3,071E-04 0,02420512 GO:0016446|somatic hypermutation of immunoglobulin genes, ! purine salvage GO:0043101 12 8 1,000 3,071E-04 0,02344871 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 1,000 3,071E-04 0,02273814 ! response to UV-B GO:0010224 17 8 1,000 3,071E-04 0,02206937 ! multicellular organismal aging GO:0010259 20 8 1,000 3,071E-04 0,02143882 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 2,000 3,302E-04 0,02241035 GO:0006956|complement activation, ! purine base metabolic process GO:0006144 25 9 1,000 3,94E-04 0,0260171 ! mitochondrion localization GO:0051646 18 9 1,000 3,94E-04 0,02533244 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 4,915E-04 0,03078602 ! motor axon guidance GO:0008045 22 10 1,000 4,915E-04 0,03001637 ! positive regulation of phagocytosis GO:0050766 14 10 1,000 4,915E-04 0,02928427 ! spinal cord motor neuron differentiation GO:0021522 19 10 1,000 4,915E-04 0,02858702 ! detection of calcium ion GO:0005513 24 10 1,000 4,915E-04 0,02792221 ! cellular metabolic compound salvage GO:0043094 16 11 1,000 5,994E-04 0,03327848 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 1,000 5,994E-04 0,03253896 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! protein homooligomerization GO:0051260 84 49 2,000 6,025E-04 0,0319961 ! ventral spinal cord development GO:0021517 25 12 1,000 7,177E-04 0,03730333 ! regulation of phagocytosis GO:0050764 17 12 1,000 7,177E-04 0,03652618 ! immunoglobulin production during immune response GO:0002381 24 12 1,000 7,177E-04 0,03578075 ! embryonic placenta development GO:0001892 21 12 1,000 7,177E-04 0,03506513 ! lamellipodium assembly GO:0030032 24 12 1,000 7,177E-04 0,03437758 ! regulation of translational initiation GO:0006446 87 54 2,000 8,013E-04 0,03764471 ! response to UV GO:0009411 120 55 2,000 8,454E-04 0,03897034 ! protein homotetramerization GO:0051289 24 13 1,000 8,463E-04 0,03828694 ! positive regulation of protein polymerization GO:0032273 27 14 1,000 9,852E-04 0,04375997 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 1,134E-03 0,04948213 ! regulation of exocytosis GO:0017157 26 15 1,000 1,134E-03 0,04861402 ! cell killing GO:0001906 32 15 1,000 1,134E-03 0,04777585 ! heterophilic cell adhesion GO:0007157 43 16 1,000 1,293E-03 0,05355813 ! pituitary gland development GO:0021983 30 16 1,000 1,293E-03 0,05266549 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 1,293E-03 0,05180212 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 1,436E-03 0,05657326 ! signal complex assembly GO:0007172 47 17 1,000 1,463E-03 0,05672099 ! negative regulation of peptidase activity GO:0010466 28 17 1,000 1,463E-03 0,05583472 ! nucleobase metabolic process GO:0009112 43 17 1,000 1,463E-03 0,05497573 ! positive regulation of protein complex assembly GO:0031334 34 18 1,000 1,642E-03 0,06077744 ! cell-substrate junction assembly GO:0007044 56 18 1,000 1,642E-03 0,05987032 ! defense response to virus GO:0051607 43 18 1,000 1,642E-03 0,05898987 ! activation of immune response GO:0002253 120 70 2,000 1,701E-03 0,06022193 ! protein maturation by peptide bond cleavage GO:0051605 118 70 2,000 1,701E-03 0,05936162 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 1,772E-03 0,06095942 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 1,831E-03 0,06213099 ! memory GO:0007613 34 19 1,000 1,831E-03 0,06127988 ! cell differentiation in spinal cord GO:0021515 37 19 1,000 1,831E-03 0,06045178 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 1,000 1,831E-03 0,05964575 ! humoral immune response GO:0006959 115 73 2,000 1,919E-03 0,06167173 ! positive regulation of angiogenesis GO:0045766 50 20 1,000 2,03E-03 0,06441063 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 1,000 2,03E-03 0,06358485 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 2,000 2,153E-03 0,06657407 ! cytosolic calcium ion homeostasis GO:0051480 149 77 2,000 2,235E-03 0,06824143 ! regulation of vesicle-mediated transport GO:0060627 136 77 2,000 2,235E-03 0,06739894 ! diencephalon development GO:0021536 36 21 1,000 2,239E-03 0,06670377 ! protein oligomerization GO:0051259 149 79 2,000 2,404E-03 0,07076216 ! cellular response to starvation GO:0009267 37 22 1,000 2,457E-03 0,07147071 ! detection of chemical stimulus GO:0009593 42 22 1,000 2,457E-03 0,07062988 ! somatic diversification of immunoglobulins GO:0016445 55 22 1,000 2,457E-03 0,0698086 ! gluconeogenesis GO:0006094 38 23 1,000 2,686E-03 0,07541321 ! regulation of DNA recombination GO:0000018 51 23 1,000 2,686E-03 0,07455624 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 2,686E-03 0,07371853 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 1,000 2,923E-03 0,07935306 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 1,000 2,923E-03 0,07848105 ! protein amino acid O-linked glycosylation GO:0006493 45 24 1,000 2,923E-03 0,07762799 ! purine ribonucleoside metabolic process GO:0046128 38 24 1,000 2,923E-03 0,07679328 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 2,923E-03 0,07597633 ! negative regulation of catabolic process GO:0009895 52 24 1,000 2,923E-03 0,07517658 ! leukocyte adhesion GO:0007159 55 25 1,000 3,171E-03 0,08068603 ! keratinization GO:0031424 37 25 1,000 3,171E-03 0,07985422 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 3,171E-03 0,07903938 ! interaction with host GO:0051701 66 25 1,000 3,171E-03 0,078241 ! immunoglobulin production GO:0002377 62 25 1,000 3,171E-03 0,07745859 GO:0002440|production of molecular mediator of immune response, ! protein tetramerization GO:0051262 57 25 1,000 3,171E-03 0,07669167 ! pyruvate metabolic process GO:0006090 43 26 1,000 3,427E-03 0,08208863 ! spinal cord development GO:0021510 54 26 1,000 3,427E-03 0,08129165 ! somatic diversification of immune receptors GO:0002200 63 26 1,000 3,427E-03 0,08051 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 3,693E-03 0,08593485 ! cellular response to nutrient levels GO:0031669 45 27 1,000 3,693E-03 0,08512415 ! response to starvation GO:0042594 47 27 1,000 3,693E-03 0,08432859 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 1,000 4,254E-03 0,09621836 ! acute-phase response GO:0006953 50 30 1,000 4,548E-03 0,10192269 ! cell fate determination GO:0001709 64 30 1,000 4,548E-03 0,10099612 ! neurotransmitter secretion GO:0007269 55 30 1,000 4,548E-03 0,10008625 ! positive regulation of immune response GO:0050778 175 100 2,000 4,672E-03 0,10191495 ! cell junction assembly GO:0034329 85 31 1,000 4,851E-03 0,10486615 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 4,851E-03 0,10394627 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 1,000 5,163E-03 0,10967247 ! positive regulation of T cell proliferation GO:0042102 60 32 1,000 5,163E-03 0,10872701 ! hexose biosynthetic process GO:0019319 53 32 1,000 5,163E-03 0,10779772 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 5,484E-03 0,11353215 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 5,814E-03 0,11935381 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 6,153E-03 0,12525925 ! positive regulation of endocytosis GO:0045807 56 35 1,000 6,153E-03 0,12422405 ! placenta development GO:0001890 53 35 1,000 6,153E-03 0,12320582 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 6,5E-03 0,12911106 ! monosaccharide biosynthetic process GO:0046364 57 36 1,000 6,5E-03 0,12806984 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 6,857E-03 0,13401284 ! cell junction organization GO:0034330 96 37 1,000 6,857E-03 0,13294925 ! meiosis I GO:0007127 74 38 1,000 7,222E-03 0,1389275 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 7,222E-03 0,13784213 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 7,596E-03 0,14385329 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mismatch repair GO:0006298 58 40 1,000 7,978E-03 0,14993308 ! alcohol biosynthetic process GO:0046165 65 42 1,000 8,769E-03 0,16352669 ! ribonucleoside metabolic process GO:0009119 64 42 1,000 8,769E-03 0,16228785 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 9,176E-03 0,16855769 GO:0090047|positive regulation of transcription regulator activity, ! regulation of T cell proliferation GO:0042129 80 43 1,000 9,176E-03 0,1672998 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 9,176E-03 0,16606054 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 0,01001697 0,17993714 ! keratinocyte differentiation GO:0030216 81 45 1,000 0,01001697 0,17862373 ! maintenance of location in cell GO:0051651 101 45 1,000 0,01001697 0,17732936 ! regulation of actin filament polymerization GO:0030833 99 46 1,000 0,01044956 0,18365658 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,01044956 0,18234475 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,01044956 0,18105152 ! cell growth GO:0016049 90 46 1,000 0,01044956 0,17977651 ! response to insulin stimulus GO:0032868 98 47 1,000 0,0108903 0,18604896 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,01133914 0,19237167 ! response to calcium ion GO:0051592 94 49 1,000 0,01179602 0,1987426 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 0,01179602 0,19738135 ! endocrine system development GO:0035270 109 50 1,000 0,01226088 0,20376417 ! epidermal cell differentiation GO:0009913 87 50 1,000 0,01226088 0,20238738 ! positive regulation of binding GO:0051099 88 52 1,000 0,01321432 0,21666156 ! histone modification GO:0016570 104 52 1,000 0,01321432 0,21521715 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 0,01370277 0,22169456 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of angiogenesis GO:0045765 125 54 1,000 0,01419899 0,22821133 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 1,000 0,01419899 0,22671976 ! covalent chromatin modification GO:0016569 115 54 1,000 0,01419899 0,22524755 ! regulation of cell shape GO:0008360 142 54 1,000 0,01419899 0,22379434 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 1,000 0,01470289 0,23025107 ! cell maturation GO:0048469 107 55 1,000 0,01470289 0,22878451 ! regulation of protein polymerization GO:0032271 117 55 1,000 0,01470289 0,2273365 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,01470289 0,22590671 ! regulation of actin filament length GO:0030832 118 58 1,000 0,01626023 0,24827336 ! aging GO:0007568 112 58 1,000 0,01626023 0,24673129 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,01626023 0,24520826 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,01626023 0,24370392 ! maintenance of location GO:0051235 124 58 1,000 0,01626023 0,24221792 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01662903 0,24621044 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01662903 0,24472724 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01662903 0,24326181 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01662903 0,24181383 ! neuron fate determination GO:0048664 7 5 0,000 0,01662903 0,24038297 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01662903 0,23896896 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01662903 0,23757148 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01662903 0,23619025 ! polyol transport GO:0015791 12 5 0,000 0,01662903 0,23482499 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01662903 0,23347542 ! response to superoxide GO:0000303 10 5 0,000 0,01662903 0,23214127 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01662903 0,23082229 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01662903 0,22951821 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01662903 0,22822878 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01662903 0,22695376 ! female meiosis GO:0007143 10 5 0,000 0,01662903 0,2256929 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01662903 0,22444598 ! hypothalamus development GO:0021854 9 5 0,000 0,01662903 0,22321276 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01662903 0,22199302 ! cobalt ion transport GO:0006824 11 5 0,000 0,01662903 0,22078654 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01662903 0,2195931 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01662903 0,21841249 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01662903 0,21724451 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01662903 0,21608895 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01662903 0,21494562 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01662903 0,21381433 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01662903 0,21269488 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01662903 0,2115871 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01662903 0,21049079 ! transposition GO:0032196 9 5 0,000 0,01662903 0,20940579 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01662903 0,20833191 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01662903 0,20726899 ! negative chemotaxis GO:0050919 16 5 0,000 0,01662903 0,20621687 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01662903 0,20517537 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01662903 0,20414433 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01662903 0,20312361 ! behavioral response to pain GO:0048266 10 5 0,000 0,01662903 0,20211305 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01662903 0,20111249 ! Notch receptor processing GO:0007220 11 5 0,000 0,01662903 0,20012179 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01662903 0,1991408 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01662903 0,19816938 ! micturition GO:0060073 9 5 0,000 0,01662903 0,19720739 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01662903 0,1962547 ! copulation GO:0007620 9 5 0,000 0,01662903 0,19531117 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01662903 0,19437666 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01662903 0,19345106 ! bioluminescence GO:0008218 9 5 0,000 0,01662903 0,19253423 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01662903 0,19162605 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01662903 0,1907264 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01662903 0,18983515 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01662903 0,1889522 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01662903 0,18807742 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01662903 0,1872107 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01662903 0,18635194 ! grooming behavior GO:0007625 6 5 0,000 0,01662903 0,18550102 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01662903 0,18465783 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01662903 0,18382227 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01662903 0,18299425 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01662903 0,18217364 ! response to protozoan GO:0001562 13 5 0,000 0,01662903 0,18136037 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,01662903 0,18055432 ! lymph vessel development GO:0001945 10 5 0,000 0,01662903 0,17975541 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01662903 0,17896354 ! endochondral ossification GO:0001958 17 5 0,000 0,01662903 0,17817861 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01662903 0,17740054 ! single strand break repair GO:0000012 8 5 0,000 0,01662903 0,17662923 ! parathyroid gland development GO:0060017 14 5 0,000 0,01662903 0,1758646 ! anagen GO:0042640 7 5 0,000 0,01662903 0,17510656 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01662903 0,17435503 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01662903 0,17360993 ! cytokine secretion GO:0050663 15 5 0,000 0,01662903 0,17287116 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01662903 0,17213866 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01662903 0,17141233 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01662903 0,17069211 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01662903 0,16997792 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01662903 0,16926968 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01662903 0,16856731 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01662903 0,16787075 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01662903 0,16717993 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01662903 0,16649476 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01662903 0,16581519 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01662903 0,16514115 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01662903 0,16447256 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01662903 0,16380937 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01662903 0,1631515 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01662903 0,16249889 ! microvillus organization GO:0032528 8 5 0,000 0,01662903 0,16185148 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01662903 0,16120922 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01662903 0,16057203 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01662903 0,15993985 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01662903 0,15931264 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01662903 0,15869032 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01662903 0,15807285 ! polyol catabolic process GO:0046174 9 5 0,000 0,01662903 0,15746017 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01662903 0,15685221 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01662903 0,15624893 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01662903 0,15565028 ! muscle cell migration GO:0014812 8 5 0,000 0,01662903 0,15505619 ! mitochondrial fission GO:0000266 8 5 0,000 0,01662903 0,15446663 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01662903 0,15388153 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01662903 0,15330084 ! mRNA transcription GO:0009299 10 5 0,000 0,01662903 0,15272452 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01662903 0,15215252 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01662903 0,15158479 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01662903 0,15102127 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01662903 0,15046194 ! monocyte activation GO:0042117 10 5 0,000 0,01662903 0,14990673 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01662903 0,1493556 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01662903 0,14880851 ! response to food GO:0032094 6 5 0,000 0,01662903 0,14826541 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01662903 0,14772626 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01662903 0,14719102 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01662903 0,14665965 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01662903 0,1461321 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,01662903 0,14560832 ! forebrain neuron development GO:0021884 13 5 0,000 0,01662903 0,1450883 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01662903 0,14457197 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01662903 0,1440593 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01662903 0,14355026 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01662903 0,1430448 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01662903 0,14254289 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01662903 0,14204448 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01662903 0,14154956 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01662903 0,14105806 ! lipid glycosylation GO:0030259 7 5 0,000 0,01662903 0,14056997 ! nucleobase transport GO:0015851 6 5 0,000 0,01662903 0,14008525 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01662903 0,13960386 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01662903 0,13912576 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01662903 0,13865093 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01662903 0,13817933 ! basic amino acid transport GO:0015802 12 5 0,000 0,01662903 0,13771092 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01662903 0,13724568 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01662903 0,13678358 ! actin nucleation GO:0045010 11 5 0,000 0,01662903 0,13632457 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01662903 0,13586864 ! depurination GO:0045007 5 5 0,000 0,01662903 0,13541574 ! depyrimidination GO:0045008 10 5 0,000 0,01662903 0,13496586 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01662903 0,13451895 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01662903 0,13407499 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01662903 0,13363396 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01662903 0,13319581 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01662903 0,13276053 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01662903 0,13232809 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01662903 0,13189845 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01662903 0,13147159 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01662903 0,13104749 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01662903 0,13062612 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01662903 0,13020744 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01662903 0,12979145 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01662903 0,1293781 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01662903 0,12896737 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01662903 0,12855925 ! response to arsenic GO:0046685 11 5 0,000 0,01662903 0,1281537 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01662903 0,1277507 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01662903 0,12735023 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01662903 0,12695226 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01662903 0,12655677 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01662903 0,12616373 ! response to mercury ion GO:0046689 8 5 0,000 0,01662903 0,12577314 ! response to cadmium ion GO:0046686 7 5 0,000 0,01662903 0,12538495 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01662903 0,12499915 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01662903 0,12461571 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01662903 0,12423463 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01662903 0,12385586 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01662903 0,1234794 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01662903 0,12310522 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01662903 0,1227333 ! decidualization GO:0046697 11 5 0,000 0,01662903 0,12236362 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01662903 0,12199616 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01662903 0,12163091 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01662903 0,12126783 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01662903 0,12090691 ! embryonic cleavage GO:0040016 6 5 0,000 0,01662903 0,12054814 ! peroxisome fission GO:0016559 5 5 0,000 0,01662903 0,12019149 ! histone demethylation GO:0016577 13 5 0,000 0,01662903 0,11983694 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01662903 0,11948448 ! mitotic recombination GO:0006312 9 5 0,000 0,01662903 0,11913408 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01662903 0,11878574 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01662903 0,11843942 ! metaphase plate congression GO:0051310 7 5 0,000 0,01662903 0,11809512 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01662903 0,11775282 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01662903 0,11741249 ! enteric nervous system development GO:0048484 8 5 0,000 0,01662903 0,11707413 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01662903 0,11673771 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01662903 0,11640322 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01662903 0,11607064 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01662903 0,11573995 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01662903 0,11541114 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01662903 0,1150842 ! B cell homeostasis GO:0001782 13 5 0,000 0,01662903 0,1147591 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01662903 0,11443584 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01662903 0,11411439 ! metaphase GO:0051323 11 5 0,000 0,01662903 0,11379474 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01662903 0,11347688 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01662903 0,11316079 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01662903 0,11284645 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01662903 0,11253386 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01662903 0,11222299 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01662903 0,11191384 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01662903 0,11160638 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01662903 0,11130061 ! response to redox state GO:0051775 6 5 0,000 0,01662903 0,11099651 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01662903 0,11069407 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01662903 0,11039327 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01662903 0,1100941 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01662903 0,10979655 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01662903 0,1095006 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01662903 0,10920624 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01662903 0,10891347 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01662903 0,10862225 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01662903 0,10833259 ! striatum development GO:0021756 14 5 0,000 0,01662903 0,10804448 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01662903 0,10775788 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01662903 0,10747281 ! glial cell migration GO:0008347 10 5 0,000 0,01662903 0,10718924 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01662903 0,10690716 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01662903 0,10662657 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01662903 0,10634744 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01662903 0,10606977 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01662903 0,10579355 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01662903 0,10551876 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01662903 0,1052454 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01662903 0,10497344 ! neuroprotection GO:0043526 8 5 0,000 0,01662903 0,10470289 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01662903 0,10443373 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01662903 0,10416596 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01662903 0,10389955 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01662903 0,1036345 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01662903 0,1033708 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01662903 0,10310843 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01662903 0,1028474 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01662903 0,10258768 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01662903 0,10232928 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01662903 0,10207217 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,01662903 0,10181635 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01662903 0,10156181 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01662903 0,10130854 ! spindle assembly GO:0051225 6 5 0,000 0,01662903 0,10105652 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01662903 0,10080576 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01662903 0,10055624 ! protein palmitoylation GO:0018345 12 5 0,000 0,01662903 0,10030796 ! drug metabolic process GO:0017144 7 5 0,000 0,01662903 0,10006089 ! stem cell division GO:0017145 11 5 0,000 0,01662903 0,09981504 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01662903 0,0995704 ! organ regeneration GO:0031100 7 5 0,000 0,01662903 0,09932695 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01662903 0,09908469 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01662903 0,09884361 ! regulation of neurotransmitter levels GO:0001505 113 60 1,000 0,01733591 0,1027952 ! regulation of endocytosis GO:0030100 104 60 1,000 0,01733591 0,10254631 ! kidney development GO:0001822 133 60 1,000 0,01733591 0,10229861 ! regulation of cellular component size GO:0032535 125 61 1,000 0,01788482 0,10528341 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,01788482 0,10503033 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,01844104 0,10803708 ! nucleoside metabolic process GO:0009116 91 62 1,000 0,01844104 0,10777862 ! regulation of protein complex assembly GO:0043254 132 63 1,000 0,01900451 0,11080675 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,01957519 0,11386235 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 0,01957519 0,11359189 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01992178 0,11532919 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01992178 0,11505654 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01992178 0,11478518 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01992178 0,1145151 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01992178 0,11424629 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01992178 0,11397873 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01992178 0,11371243 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01992178 0,11344736 ! response to oxygen radical GO:0000305 11 6 0,000 0,01992178 0,11318353 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01992178 0,11292092 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01992178 0,11265953 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01992178 0,11239935 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01992178 0,11214036 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01992178 0,11188257 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01992178 0,11162596 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01992178 0,11137052 ! forebrain regionalization GO:0021871 9 6 0,000 0,01992178 0,11111625 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01992178 0,11086314 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01992178 0,11061118 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01992178 0,11036036 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01992178 0,11011067 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01992178 0,10986212 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01992178 0,10961468 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01992178 0,10936835 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01992178 0,10912313 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01992178 0,10887901 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01992178 0,10863598 ! malate metabolic process GO:0006108 13 6 0,000 0,01992178 0,10839403 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01992178 0,10815315 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01992178 0,10791334 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01992178 0,1076746 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01992178 0,10743691 ! protein refolding GO:0042026 15 6 0,000 0,01992178 0,10720026 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01992178 0,10696465 ! opsonization GO:0008228 8 6 0,000 0,01992178 0,10673008 ! mating behavior GO:0007617 7 6 0,000 0,01992178 0,10649654 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01992178 0,10626401 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01992178 0,1060325 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01992178 0,105802 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01992178 0,10557249 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01992178 0,10534398 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01992178 0,10511645 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01992178 0,10488991 ! toxin metabolic process GO:0009404 11 6 0,000 0,01992178 0,10466434 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01992178 0,10443974 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01992178 0,1042161 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01992178 0,10399341 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01992178 0,10377168 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01992178 0,10355089 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01992178 0,10333104 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01992178 0,10311211 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01992178 0,10289412 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01992178 0,10267704 ! thymic T cell selection GO:0045061 16 6 0,000 0,01992178 0,10246088 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01992178 0,10224563 ! protein lipoylation GO:0009249 10 6 0,000 0,01992178 0,10203127 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01992178 0,10181782 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01992178 0,10160526 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01992178 0,10139358 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01992178 0,10118278 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01992178 0,10097286 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01992178 0,10076381 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01992178 0,10055562 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01992178 0,10034828 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01992178 0,10014181 ! hyperosmotic response GO:0006972 10 6 0,000 0,01992178 0,09993618 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01992178 0,09973139 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01992178 0,09952744 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01992178 0,09932432 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01992178 0,09912203 ! urea metabolic process GO:0019627 7 6 0,000 0,01992178 0,09892056 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01992178 0,09871991 ! neutrophil activation GO:0042119 7 6 0,000 0,01992178 0,09852008 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01992178 0,09832105 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01992178 0,09812282 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01992178 0,09792539 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01992178 0,09772875 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01992178 0,0975329 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01992178 0,09733784 ! neuron apoptosis GO:0051402 15 6 0,000 0,01992178 0,09714355 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01992178 0,09695004 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01992178 0,09675729 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01992178 0,09656531 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01992178 0,09637409 ! carnitine transport GO:0015879 10 6 0,000 0,01992178 0,09618363 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01992178 0,09599392 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01992178 0,09580496 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01992178 0,09561673 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01992178 0,09542925 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01992178 0,0952425 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01992178 0,09505648 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01992178 0,09487119 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01992178 0,09468661 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01992178 0,09450275 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01992178 0,09431961 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01992178 0,09413717 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01992178 0,09395544 ! response to UV-C GO:0010225 14 6 0,000 0,01992178 0,09377441 ! astrocyte development GO:0014002 16 6 0,000 0,01992178 0,09359407 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01992178 0,09341443 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01992178 0,09323548 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01992178 0,0930572 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01992178 0,09287961 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01992178 0,0927027 ! response to copper ion GO:0046688 10 6 0,000 0,01992178 0,09252646 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01992178 0,09235089 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01992178 0,09217598 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01992178 0,09200174 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01992178 0,09182815 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01992178 0,09165521 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01992178 0,09148293 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01992178 0,09131129 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01992178 0,0911403 ! hair follicle maturation GO:0048820 8 6 0,000 0,01992178 0,09096994 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01992178 0,09080022 ! Schwann cell development GO:0014044 15 6 0,000 0,01992178 0,09063113 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01992178 0,09046267 ! response to pheromone GO:0019236 6 6 0,000 0,01992178 0,09029484 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01992178 0,09012763 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01992178 0,08996103 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01992178 0,08979505 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01992178 0,08962968 ! subpallium development GO:0021544 15 6 0,000 0,01992178 0,08946492 ! neural tube patterning GO:0021532 8 6 0,000 0,01992178 0,08930077 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01992178 0,08913721 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01992178 0,08897426 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01992178 0,08881189 ! G2 phase GO:0051319 16 6 0,000 0,01992178 0,08865012 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01992178 0,08848894 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01992178 0,08832834 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01992178 0,08816833 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01992178 0,08800889 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01992178 0,08785003 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01992178 0,08769174 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01992178 0,08753403 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01992178 0,08737687 ! receptor internalization GO:0031623 11 6 0,000 0,01992178 0,08722028 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01992178 0,08706425 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01992178 0,08690878 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01992178 0,08675386 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01992178 0,0865995 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01992178 0,08644568 ! protein deubiquitination GO:0016579 16 6 0,000 0,01992178 0,08629241 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01992178 0,08613968 ! protein destabilization GO:0031648 9 6 0,000 0,01992178 0,08598749 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01992178 0,08583583 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01992178 0,08568471 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01992178 0,08553413 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01992178 0,08538407 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01992178 0,08523453 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01992178 0,08508552 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01992178 0,08493703 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01992178 0,08478906 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01992178 0,0846416 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01992178 0,08449465 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01992178 0,08434821 ! neural plate development GO:0001840 9 6 0,000 0,01992178 0,08420228 ! catecholamine transport GO:0051937 9 6 0,000 0,01992178 0,08405685 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01992178 0,08391193 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01992178 0,0837675 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01992178 0,08362357 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01992178 0,08348013 ! maternal placenta development GO:0001893 12 6 0,000 0,01992178 0,08333719 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01992178 0,08319473 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01992178 0,08305276 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01992178 0,08291127 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01992178 0,08277027 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01992178 0,08262974 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01992178 0,08248969 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01992178 0,08235012 GO:0055081|anion homeostasis, ! extracellular matrix organization GO:0030198 146 68 1,000 0,02192882 0,09049343 ! positive regulation of T cell activation GO:0050870 124 68 1,000 0,02192882 0,09034082 ! cell projection assembly GO:0030031 138 68 1,000 0,02192882 0,09018874 ! urogenital system development GO:0001655 149 69 1,000 0,0225347 0,09252481 ! developmental maturation GO:0021700 128 69 1,000 0,0225347 0,09236957 ! tRNA transcription GO:0009304 17 7 0,000 0,0232036 0,0949521 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,0232036 0,09479332 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,0232036 0,09463506 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,0232036 0,09447734 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,0232036 0,09432014 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,0232036 0,09416346 ! sleep GO:0030431 16 7 0,000 0,0232036 0,0940073 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,0232036 0,09385166 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,0232036 0,09369653 ! prostate gland development GO:0030850 14 7 0,000 0,0232036 0,09354192 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,0232036 0,09338781 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0232036 0,09323422 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,0232036 0,09308112 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,0232036 0,09292853 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0232036 0,09277644 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,0232036 0,09262484 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,0232036 0,09247374 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,0232036 0,09232313 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,0232036 0,09217301 ! glycolipid transport GO:0046836 11 7 0,000 0,0232036 0,09202338 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,0232036 0,09187424 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,0232036 0,09172557 ! neuron adhesion GO:0007158 14 7 0,000 0,0232036 0,09157739 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,0232036 0,09142968 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,0232036 0,09128245 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,0232036 0,0911357 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,0232036 0,09098941 ! mRNA stabilization GO:0048255 18 7 0,000 0,0232036 0,0908436 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,0232036 0,09069825 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,0232036 0,09055336 GO:0031958|corticosteroid receptor signaling pathway, ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,0232036 0,09040894 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,0232036 0,09026497 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,0232036 0,09012147 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,0232036 0,08997842 ! lipoprotein transport GO:0042953 14 7 0,000 0,0232036 0,08983582 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,0232036 0,08969368 ! rhythmic behavior GO:0007622 17 7 0,000 0,0232036 0,08955198 ! neuron remodeling GO:0016322 16 7 0,000 0,0232036 0,08941073 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,0232036 0,08926993 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,0232036 0,08912957 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,0232036 0,08898964 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,0232036 0,08885016 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,0232036 0,08871112 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,0232036 0,08857251 ! mechanosensory behavior GO:0007638 16 7 0,000 0,0232036 0,08843433 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,0232036 0,08829658 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,0232036 0,08815926 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,0232036 0,08802237 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,0232036 0,0878859 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0232036 0,08774985 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0232036 0,08761422 ! spinal cord patterning GO:0021511 14 7 0,000 0,0232036 0,08747902 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,0232036 0,08734423 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,0232036 0,08720985 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,0232036 0,08707589 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,0232036 0,08694234 ! adrenal gland development GO:0030325 17 7 0,000 0,0232036 0,08680919 ! cysteine metabolic process GO:0006534 13 7 0,000 0,0232036 0,08667646 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,0232036 0,08654413 ! ovulation GO:0030728 10 7 0,000 0,0232036 0,0864122 ! adenohypophysis development GO:0021984 11 7 0,000 0,0232036 0,08628067 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,0232036 0,08614955 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,0232036 0,08601882 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,0232036 0,08588849 ! microtubule nucleation GO:0007020 21 7 0,000 0,0232036 0,08575855 ! proline biosynthetic process GO:0006561 10 7 0,000 0,0232036 0,08562901 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,0232036 0,08549985 ! thyroid hormone generation GO:0006590 13 7 0,000 0,0232036 0,08537109 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,0232036 0,08524271 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,0232036 0,08511472 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0232036 0,08498711 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,0232036 0,08485989 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,0232036 0,08473304 ! galactose metabolic process GO:0006012 13 7 0,000 0,0232036 0,08460657 ! vesicle fusion GO:0006906 20 7 0,000 0,0232036 0,08448048 ! response to dietary excess GO:0002021 8 7 0,000 0,0232036 0,08435477 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,0232036 0,08422943 ! intracellular pH reduction GO:0051452 13 7 0,000 0,0232036 0,08410446 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,0232036 0,08397986 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,0232036 0,08385563 ! organ growth GO:0035265 15 7 0,000 0,0232036 0,08373176 ! nucleoside transport GO:0015858 11 7 0,000 0,0232036 0,08360826 ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,0232036 0,08348513 ! male sex determination GO:0030238 15 7 0,000 0,0232036 0,08336236 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,0232036 0,08323995 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! parturition GO:0007567 16 7 0,000 0,0232036 0,08311789 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,0232036 0,0829962 ! rRNA modification GO:0000154 14 7 0,000 0,0232036 0,08287486 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,0232036 0,08275387 ! spindle checkpoint GO:0031577 16 7 0,000 0,0232036 0,08263324 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,0232036 0,08251296 ! monocyte differentiation GO:0030224 16 7 0,000 0,0232036 0,08239303 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,0232036 0,08227344 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,0232036 0,08215421 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,0232036 0,08203532 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,0232036 0,08191677 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,0232036 0,08179856 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,0232036 0,0816807 ! fibrinolysis GO:0042730 11 7 0,000 0,0232036 0,08156317 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,0232036 0,08144598 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,0232036 0,08132913 ! eating behavior GO:0042755 8 7 0,000 0,0232036 0,08121261 ! B cell lineage commitment GO:0002326 21 7 0,000 0,0232036 0,08109643 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,0232036 0,08098058 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,0232036 0,08086505 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,0232036 0,08074986 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,0232036 0,080635 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,0232036 0,08052046 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,0232036 0,08040625 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,0232036 0,08029236 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,0232036 0,08017879 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,0232036 0,08006554 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,0232036 0,07995261 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,0232036 0,07984 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,0232036 0,07972771 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,0232036 0,07961574 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,0232036 0,07950407 ! histone ubiquitination GO:0016574 9 7 0,000 0,0232036 0,07939272 ! regulation of meiosis GO:0040020 12 7 0,000 0,0232036 0,07928168 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,0232036 0,07917095 ! T cell lineage commitment GO:0002360 16 7 0,000 0,0232036 0,07906053 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,0232036 0,07895042 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,0232036 0,07884062 ! membrane to membrane docking GO:0022614 14 7 0,000 0,0232036 0,07873112 ! transcription termination GO:0006353 14 7 0,000 0,0232036 0,07862192 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,0232036 0,07851302 ! anaphase GO:0051322 18 7 0,000 0,0232036 0,07840443 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,0232036 0,07829614 ! axonal fasciculation GO:0007413 19 7 0,000 0,0232036 0,07818814 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,0232036 0,07808045 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,0232036 0,07797304 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,0232036 0,07786594 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,0232036 0,07775913 ! diuresis GO:0030146 12 7 0,000 0,0232036 0,07765261 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,0232036 0,07754638 ! thiamin metabolic process GO:0006772 7 7 0,000 0,0232036 0,07744044 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0232036 0,07733479 ! antibiotic transport GO:0042891 9 7 0,000 0,0232036 0,07722943 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,0232036 0,07712436 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,0232036 0,07701957 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,0232036 0,07691507 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,0232036 0,07681084 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,0232036 0,07670691 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,0232036 0,07660325 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,0232036 0,07649987 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,0232036 0,07639677 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,0232036 0,07629395 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,0232036 0,0761914 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,0232036 0,07608913 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,0232036 0,07598714 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,0232036 0,07588541 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,0232036 0,07578396 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,0232036 0,07568278 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,0232036 0,07558187 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,0232036 0,07548123 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,0232036 0,07538086 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,0232036 0,07528075 ! muscle adaptation GO:0043500 13 7 0,000 0,0232036 0,07518091 ! embryonic heart tube development GO:0035050 14 7 0,000 0,0232036 0,07508133 ! retina homeostasis GO:0001895 12 7 0,000 0,0232036 0,07498202 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,0232036 0,07488296 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,0232036 0,07478417 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,0232036 0,07468564 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,0232036 0,07458737 ! actin filament organization GO:0007015 167 72 1,000 0,02439341 0,07830894 ! B cell activation GO:0042113 179 72 1,000 0,02439341 0,07820617 ! organelle localization GO:0051640 155 74 1,000 0,02566628 0,08217918 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,02631267 0,08413855 GO:0090046|regulation of transcription regulator activity, ! axon guidance GO:0007411 162 75 1,000 0,02631267 0,08402857 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02647453 0,08443507 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02647453 0,08432499 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,02647453 0,08421519 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02647453 0,08410568 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02647453 0,08399645 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02647453 0,08388751 ! male meiosis GO:0007140 9 8 0,000 0,02647453 0,08377884 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02647453 0,08367046 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02647453 0,08356236 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 14 8 0,000 0,02647453 0,08345454 ! response to zinc ion GO:0010043 12 8 0,000 0,02647453 0,08334699 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,02647453 0,08323973 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02647453 0,08313273 ! oligopeptide transport GO:0006857 16 8 0,000 0,02647453 0,08302602 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02647453 0,08291957 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02647453 0,0828134 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02647453 0,0827075 ! signal peptide processing GO:0006465 12 8 0,000 0,02647453 0,08260187 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,02647453 0,08249651 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02647453 0,08239142 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02647453 0,0822866 ! succinate metabolic process GO:0006105 17 8 0,000 0,02647453 0,08218204 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02647453 0,08207775 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02647453 0,08197372 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02647453 0,08186996 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02647453 0,08176646 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02647453 0,08166322 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02647453 0,08156024 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02647453 0,08145752 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02647453 0,08135505 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02647453 0,08125285 ! reflex GO:0060004 17 8 0,000 0,02647453 0,0811509 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02647453 0,08104921 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,02647453 0,08094777 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,02647453 0,08084658 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02647453 0,08074565 ! pigment granule organization GO:0048753 17 8 0,000 0,02647453 0,08064497 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02647453 0,08054454 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02647453 0,08044436 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02647453 0,08034443 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02647453 0,08024475 ! histidine catabolic process GO:0006548 10 8 0,000 0,02647453 0,08014531 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02647453 0,08004612 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02647453 0,07994718 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02647453 0,07984848 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,02647453 0,07975002 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02647453 0,07965181 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,02647453 0,07955383 ! melanin metabolic process GO:0006582 17 8 0,000 0,02647453 0,0794561 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02647453 0,07935861 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02647453 0,07926136 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02647453 0,07916434 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02647453 0,07906756 ! macrophage activation GO:0042116 13 8 0,000 0,02647453 0,07897102 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02647453 0,07887472 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02647453 0,07877864 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,02647453 0,07868281 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02647453 0,0785872 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02647453 0,07849183 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02647453 0,07839669 ! osteoblast development GO:0002076 17 8 0,000 0,02647453 0,07830178 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02647453 0,07820709 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02647453 0,07811264 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,02647453 0,07801842 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02647453 0,07792442 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02647453 0,07783065 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02647453 0,0777371 ! intermediate filament organization GO:0045109 12 8 0,000 0,02647453 0,07764378 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,02647453 0,07755068 ! cellular extravasation GO:0045123 13 8 0,000 0,02647453 0,0774578 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02647453 0,07736515 ! response to antibiotic GO:0046677 11 8 0,000 0,02647453 0,07727272 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02647453 0,07718051 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02647453 0,07708852 ! DNA topological change GO:0006265 12 8 0,000 0,02647453 0,07699675 ! response to tropane GO:0014073 15 8 0,000 0,02647453 0,07690519 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,02647453 0,07681386 ! melanosome transport GO:0032402 13 8 0,000 0,02647453 0,07672274 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 0,02647453 0,07663183 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02647453 0,07654114 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02647453 0,07645067 ! mast cell activation GO:0045576 14 8 0,000 0,02647453 0,07636041 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,02647453 0,07627036 ! gas homeostasis GO:0033483 14 8 0,000 0,02647453 0,07618053 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02647453 0,0760909 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02647453 0,07600149 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02647453 0,07591229 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02647453 0,07582329 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02647453 0,0757345 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,02647453 0,07564593 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02647453 0,07555755 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02647453 0,07546939 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02647453 0,07538143 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02647453 0,07529368 ! response to tumor cell GO:0002347 16 8 0,000 0,02647453 0,07520612 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02647453 0,07511878 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,02647453 0,07503163 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,02647453 0,07494469 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,02647453 0,07485795 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02647453 0,07477141 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,02647453 0,07468507 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02647453 0,07459892 ! hormone catabolic process GO:0042447 17 8 0,000 0,02647453 0,07451298 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02647453 0,07442723 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02647453 0,07434169 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,02647453 0,07425633 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02647453 0,07417118 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02647453 0,07408622 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,02647453 0,07400145 ! adult feeding behavior GO:0008343 10 8 0,000 0,02647453 0,07391688 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02647453 0,0738325 ! ATP catabolic process GO:0006200 11 8 0,000 0,02647453 0,07374831 ! blastocyst growth GO:0001832 19 8 0,000 0,02647453 0,07366431 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02647453 0,07358051 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02647453 0,07349689 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02647453 0,07341347 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02647453 0,07333023 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02647453 0,07324719 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,02647453 0,07316433 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02647453 0,07308166 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02647453 0,07299917 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02647453 0,07291687 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02647453 0,07283476 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02647453 0,07275283 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,02647453 0,07267109 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02647453 0,07258953 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02647453 0,07250815 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,02647453 0,07242695 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,02647453 0,07234594 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02647453 0,0722651 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,02647453 0,07218445 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,02647453 0,07210398 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,02647453 0,07202368 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,02696564 0,07327815 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 0,02696564 0,07319673 ! learning or memory GO:0007611 161 76 1,000 0,02696564 0,07311549 ! neurotransmitter transport GO:0006836 142 77 1,000 0,02762513 0,07482062 ! regulation of catabolic process GO:0009894 173 77 1,000 0,02762513 0,07473776 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,0282911 0,07645481 ! regulation of actin filament-based process GO:0032970 170 79 1,000 0,02896349 0,07818541 ! axon extension GO:0048675 16 9 0,000 0,02973459 0,08017836 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02973459 0,08008996 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02973459 0,08000176 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,02973459 0,07991375 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02973459 0,07982593 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02973459 0,07973831 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02973459 0,07965087 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02973459 0,07956363 ! reproductive behavior GO:0019098 22 9 0,000 0,02973459 0,07947658 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02973459 0,07938972 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02973459 0,07930305 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02973459 0,07921657 ! UTP metabolic process GO:0046051 10 9 0,000 0,02973459 0,07913028 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,02973459 0,07904417 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,02973459 0,07895826 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02973459 0,07887253 ! artery development GO:0060840 25 9 0,000 0,02973459 0,07878698 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02973459 0,07870162 ! regulation of glycolysis GO:0006110 20 9 0,000 0,02973459 0,07861645 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02973459 0,07853146 ! equilibrioception GO:0050957 20 9 0,000 0,02973459 0,07844665 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02973459 0,07836202 ! chemosensory behavior GO:0007635 21 9 0,000 0,02973459 0,07827758 ! microtubule bundle formation GO:0001578 22 9 0,000 0,02973459 0,07819332 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02973459 0,07810924 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02973459 0,07802535 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02973459 0,07794163 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02973459 0,07785809 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02973459 0,07777473 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02973459 0,07769155 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02973459 0,07760854 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02973459 0,07752572 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02973459 0,07744307 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02973459 0,07736059 ! protein targeting to ER GO:0045047 25 9 0,000 0,02973459 0,07727829 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02973459 0,07719617 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02973459 0,07711422 ! T cell selection GO:0045058 27 9 0,000 0,02973459 0,07703245 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,02973459 0,07695084 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02973459 0,07686941 ! glycine catabolic process GO:0006546 15 9 0,000 0,02973459 0,07678816 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02973459 0,07670707 ! endosome organization GO:0007032 20 9 0,000 0,02973459 0,07662616 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02973459 0,07654541 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,02973459 0,07646484 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02973459 0,07638443 ! mannose metabolic process GO:0006013 13 9 0,000 0,02973459 0,0763042 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02973459 0,07622413 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02973459 0,07614423 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,02973459 0,0760645 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02973459 0,07598493 ! receptor clustering GO:0043113 20 9 0,000 0,02973459 0,07590553 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02973459 0,0758263 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02973459 0,07574723 ! retinol metabolic process GO:0042572 20 9 0,000 0,02973459 0,07566833 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02973459 0,07558959 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02973459 0,07551101 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02973459 0,0754326 ! macrophage differentiation GO:0030225 15 9 0,000 0,02973459 0,07535435 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02973459 0,07527627 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,02973459 0,07519834 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02973459 0,07512058 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02973459 0,07504297 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02973459 0,07496553 ! response to amine stimulus GO:0014075 13 9 0,000 0,02973459 0,07488824 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02973459 0,07481112 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02973459 0,07473415 ! erythrocyte development GO:0048821 17 9 0,000 0,02973459 0,07465734 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02973459 0,07458069 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02973459 0,0745042 ! renal water homeostasis GO:0003091 15 9 0,000 0,02973459 0,07442787 ! postreplication repair GO:0006301 25 9 0,000 0,02973459 0,07435169 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02973459 0,07427566 ! icosanoid secretion GO:0032309 15 9 0,000 0,02973459 0,07419979 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02973459 0,07412408 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02973459 0,07404852 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02973459 0,07397311 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02973459 0,07389786 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02973459 0,07382276 ! sterol catabolic process GO:0016127 14 9 0,000 0,02973459 0,07374781 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02973459 0,07367302 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02973459 0,07359838 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02973459 0,07352388 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02973459 0,07344954 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,02973459 0,07337535 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02973459 0,07330131 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,02973459 0,07322742 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02973459 0,07315367 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02973459 0,07308008 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02973459 0,07300663 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02973459 0,07293333 ! pigment granule transport GO:0051904 17 9 0,000 0,02973459 0,07286018 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,02973459 0,07278717 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02973459 0,07271431 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02973459 0,0726416 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02973459 0,07256903 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02973459 0,0724966 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02973459 0,07242432 ! meiosis GO:0007126 143 81 1,000 0,03032734 0,0737945 GO:0051327|M phase of meiotic cell cycle, ! regulation of peptidase activity GO:0052547 150 82 1,000 0,0310187 0,07540167 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,0310187 0,07532672 ! meiotic cell cycle GO:0051321 144 82 1,000 0,0310187 0,07525192 ! response to metal ion GO:0010038 158 84 1,000 0,03242005 0,0785736 ! T cell activation GO:0042110 189 84 1,000 0,03242005 0,07849573 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,03298382 0,07978166 ! regulation of developmental growth GO:0048638 16 10 0,000 0,03298382 0,07970275 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,03298382 0,07962399 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,03298382 0,07954539 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03298382 0,07946694 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,03298382 0,07938865 ! associative learning GO:0008306 21 10 0,000 0,03298382 0,07931051 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,03298382 0,07923253 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03298382 0,07915469 ! phosphate transport GO:0006817 24 10 0,000 0,03298382 0,07907702 ! cell volume homeostasis GO:0006884 17 10 0,000 0,03298382 0,07899949 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,03298382 0,07892211 ! CTP metabolic process GO:0046036 11 10 0,000 0,03298382 0,07884489 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,03298382 0,07876782 ! GTP metabolic process GO:0046039 11 10 0,000 0,03298382 0,0786909 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,03298382 0,07861413 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,03298382 0,0785375 ! social behavior GO:0035176 29 10 0,000 0,03298382 0,07846103 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,03298382 0,07838471 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,03298382 0,07830853 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,03298382 0,0782325 ! androgen metabolic process GO:0008209 17 10 0,000 0,03298382 0,07815662 ! phospholipid efflux GO:0033700 19 10 0,000 0,03298382 0,07808089 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03298382 0,0780053 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,03298382 0,07792986 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,03298382 0,07785457 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,03298382 0,07777942 ! lung alveolus development GO:0048286 26 10 0,000 0,03298382 0,07770442 ! pathogenesis GO:0009405 17 10 0,000 0,03298382 0,07762956 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03298382 0,07755484 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,03298382 0,07748027 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,03298382 0,07740584 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,03298382 0,07733155 ! endoderm development GO:0007492 18 10 0,000 0,03298382 0,07725741 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,03298382 0,07718341 ! arginine catabolic process GO:0006527 17 10 0,000 0,03298382 0,07710955 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03298382 0,07703583 ! proline metabolic process GO:0006560 13 10 0,000 0,03298382 0,07696225 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03298382 0,07688882 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,03298382 0,07681552 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,03298382 0,07674236 ! V(D)J recombination GO:0033151 34 10 0,000 0,03298382 0,07666934 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,03298382 0,07659646 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,03298382 0,07652372 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,03298382 0,07645112 ! B cell proliferation GO:0042100 19 10 0,000 0,03298382 0,07637865 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,03298382 0,07630632 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,03298382 0,07623413 ! multicellular organism growth GO:0035264 19 10 0,000 0,03298382 0,07616208 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,03298382 0,07609016 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,03298382 0,07601838 ! ruffle organization GO:0031529 17 10 0,000 0,03298382 0,07594673 ! epithelial cell development GO:0002064 21 10 0,000 0,03298382 0,07587522 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,03298382 0,07580384 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03298382 0,07573259 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,03298382 0,07566148 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,03298382 0,07559051 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,03298382 0,07551966 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,03298382 0,07544895 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,03298382 0,07537837 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03298382 0,07530792 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03298382 0,07523761 ! protein heterooligomerization GO:0051291 17 10 0,000 0,03298382 0,07516742 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03298382 0,07509737 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03298382 0,07502745 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,03298382 0,07495765 ! segment specification GO:0007379 15 10 0,000 0,03298382 0,07488799 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,03298382 0,07481846 ! blastoderm segmentation GO:0007350 19 10 0,000 0,03298382 0,07474905 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,03298382 0,07467978 ! response to dsRNA GO:0043331 23 10 0,000 0,03298382 0,07461063 ! DNA ligation GO:0006266 18 10 0,000 0,03298382 0,07454161 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,03298382 0,07447272 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03298382 0,07440395 ! melanosome localization GO:0032400 16 10 0,000 0,03298382 0,07433531 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,03298382 0,0742668 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,03298382 0,07419841 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,03298382 0,07413016 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03298382 0,07406202 ! induction of an organ GO:0001759 17 10 0,000 0,03298382 0,07399401 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,03298382 0,07392613 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,03298382 0,07385837 ! protein sumoylation GO:0016925 17 10 0,000 0,03298382 0,07379073 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,03298382 0,07372322 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03298382 0,07365583 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03298382 0,07358856 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03298382 0,07352142 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,03298382 0,0734544 ! salivary gland development GO:0007431 28 10 0,000 0,03298382 0,0733875 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,03298382 0,07332073 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,03298382 0,07325407 ! midbrain development GO:0030901 14 10 0,000 0,03298382 0,07318754 ! musculoskeletal movement GO:0050881 16 10 0,000 0,03298382 0,07312112 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,03298382 0,07305483 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,03298382 0,07298866 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,03298382 0,07292261 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,03298382 0,07285667 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,03298382 0,07279086 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03298382 0,07272516 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03298382 0,07265958 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,03298382 0,07259412 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,03298382 0,07252878 GO:0043470|regulation of carbohydrate catabolic process, ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03298382 0,07246356 ! blastocyst formation GO:0001825 18 10 0,000 0,03298382 0,07239845 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,03298382 0,07233346 ! cerebellar cortex development GO:0021695 16 10 0,000 0,03298382 0,07226859 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,03298382 0,07220383 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,03298382 0,07213919 ! response to nicotine GO:0035094 20 10 0,000 0,03298382 0,07207467 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,03298382 0,07201026 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03298382 0,07194596 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,03312995 0,07220023 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,03384592 0,07369482 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 1,000 0,03456793 0,07519987 ! regulation of DNA binding GO:0051101 167 89 1,000 0,03602986 0,07831045 ! cellular defense response GO:0006968 123 89 1,000 0,03602986 0,07824084 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,03622227 0,07858881 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,03622227 0,07851908 ! neuron fate specification GO:0048665 18 11 0,000 0,03622227 0,07844947 ! telencephalon cell migration GO:0022029 23 11 0,000 0,03622227 0,07837998 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,03622227 0,07831062 ! thyroid gland development GO:0030878 26 11 0,000 0,03622227 0,07824138 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,03622227 0,07817226 ! synapsis GO:0007129 14 11 0,000 0,03622227 0,07810327 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,03622227 0,07803439 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,03622227 0,07796564 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,03622227 0,07789701 ! response to pain GO:0048265 27 11 0,000 0,03622227 0,0778285 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03622227 0,07776011 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,03622227 0,07769184 ! blood vessel remodeling GO:0001974 30 11 0,000 0,03622227 0,07762369 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,03622227 0,07755565 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,03622227 0,07748774 ! bone resorption GO:0045453 16 11 0,000 0,03622227 0,07741995 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,03622227 0,07735227 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,03622227 0,07728472 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03622227 0,07721728 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03622227 0,07714996 ! melanocyte differentiation GO:0030318 20 11 0,000 0,03622227 0,07708275 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,03622227 0,07701567 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,03622227 0,0769487 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,03622227 0,07688184 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,03622227 0,07681511 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,03622227 0,07674848 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,03622227 0,07668198 ! UV protection GO:0009650 20 11 0,000 0,03622227 0,07661559 ! adult heart development GO:0007512 16 11 0,000 0,03622227 0,07654931 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,03622227 0,07648315 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03622227 0,0764171 ! macroautophagy GO:0016236 19 11 0,000 0,03622227 0,07635117 ! temperature homeostasis GO:0001659 18 11 0,000 0,03622227 0,07628535 ! behavioral fear response GO:0001662 27 11 0,000 0,03622227 0,07621964 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,03622227 0,07615405 ! negative regulation of ossification GO:0030279 27 11 0,000 0,03622227 0,07608857 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,03622227 0,0760232 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,03622227 0,07595794 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,03622227 0,0758928 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,03622227 0,07582776 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,03622227 0,07576284 ! regulation of organ growth GO:0046620 14 11 0,000 0,03622227 0,07569803 ! pigment granule localization GO:0051875 20 11 0,000 0,03622227 0,07563333 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,03622227 0,07556875 ! vasoconstriction GO:0042310 20 11 0,000 0,03622227 0,07550427 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,03622227 0,0754399 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03622227 0,07537564 ! embryonic axis specification GO:0000578 19 11 0,000 0,03622227 0,07531149 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,03622227 0,07524745 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03622227 0,07518352 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,03622227 0,0751197 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,03622227 0,07505598 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03622227 0,07499237 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,03622227 0,07492887 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,03622227 0,07486548 ! prophase GO:0051324 17 11 0,000 0,03622227 0,0748022 ! neuroblast proliferation GO:0007405 25 11 0,000 0,03622227 0,07473902 ! nucleosome positioning GO:0016584 15 11 0,000 0,03622227 0,07467595 ! regulation of isotype switching GO:0045191 24 11 0,000 0,03622227 0,07461299 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,03622227 0,07455013 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,03622227 0,07448737 ! apical protein localization GO:0045176 18 11 0,000 0,03622227 0,07442473 ! acid secretion GO:0046717 20 11 0,000 0,03622227 0,07436219 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03622227 0,07429975 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,03622227 0,07423742 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,03622227 0,07417519 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,03622227 0,07411307 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,03622227 0,07405105 ! thymus development GO:0048538 29 11 0,000 0,03622227 0,07398913 ! cholesterol efflux GO:0033344 21 11 0,000 0,03622227 0,07392732 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03622227 0,07386561 ! oocyte development GO:0048599 20 11 0,000 0,03622227 0,073804 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,03622227 0,0737425 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,03622227 0,0736811 ! embryonic gut development GO:0048566 19 11 0,000 0,03622227 0,0736198 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,03622227 0,0735586 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,03622227 0,07349751 ! activation of innate immune response GO:0002218 16 11 0,000 0,03622227 0,07343652 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,03622227 0,07337562 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,03622227 0,07331483 ! lysogeny GO:0030069 22 11 0,000 0,03622227 0,07325414 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03622227 0,07319355 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,03622227 0,07313306 ! sequestering of metal ion GO:0051238 15 11 0,000 0,03622227 0,07307267 ! regulation of embryonic development GO:0045995 35 11 0,000 0,03622227 0,07301238 ! nucleus localization GO:0051647 22 11 0,000 0,03622227 0,07295219 ! response to inorganic substance GO:0010035 173 90 1,000 0,03676968 0,07399368 ! ossification GO:0001503 205 91 1,000 0,03751535 0,07543209 ! gland development GO:0048732 220 91 1,000 0,03751535 0,07537006 ! bone development GO:0060348 206 92 1,000 0,03826681 0,07681661 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,03902402 0,07827232 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,03944996 0,07906173 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,03944996 0,07899693 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,03944996 0,07893223 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,03944996 0,07886764 ! virus-host interaction GO:0019048 30 12 0,000 0,03944996 0,07880315 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,03944996 0,07873877 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,03944996 0,07867449 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03944996 0,07861032 ! protein complex disassembly GO:0043241 28 12 0,000 0,03944996 0,07854625 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03944996 0,07848229 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,03944996 0,07841843 ! hippocampus development GO:0021766 29 12 0,000 0,03944996 0,07835468 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,03944996 0,07829102 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,03944996 0,07822748 ! T cell proliferation GO:0042098 32 12 0,000 0,03944996 0,07816403 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03944996 0,07810069 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,03944996 0,07803745 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,03944996 0,07797431 ! drug transport GO:0015893 16 12 0,000 0,03944996 0,07791128 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,03944996 0,07784834 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,03944996 0,07778551 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,03944996 0,07772278 ! polyamine metabolic process GO:0006595 18 12 0,000 0,03944996 0,07766015 ! focal adhesion formation GO:0048041 37 12 0,000 0,03944996 0,07759763 ! mitotic spindle organization GO:0007052 23 12 0,000 0,03944996 0,0775352 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,03944996 0,07747287 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,03944996 0,07741064 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,03944996 0,07734852 ! lipid digestion GO:0044241 21 12 0,000 0,03944996 0,07728649 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,03944996 0,07722456 ! entry into host cell GO:0030260 34 12 0,000 0,03944996 0,07716273 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03944996 0,077101 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,03944996 0,07703937 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,03944996 0,07697784 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03944996 0,0769164 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,03944996 0,07685506 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,03944996 0,07679383 ! snRNA metabolic process GO:0016073 30 12 0,000 0,03944996 0,07673268 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,03944996 0,07667164 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,03944996 0,07661069 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03944996 0,07654984 ! cranial nerve development GO:0021545 23 12 0,000 0,03944996 0,07648909 ! fucose catabolic process GO:0019317 25 12 0,000 0,03944996 0,07642843 GO:0042355|L-fucose catabolic process, ! histone acetylation GO:0016573 27 12 0,000 0,03944996 0,07636787 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,03944996 0,0763074 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03944996 0,07624703 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,03944996 0,07618676 ! zymogen activation GO:0031638 18 12 0,000 0,03944996 0,07612658 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,03944996 0,0760665 ! T cell homeostasis GO:0043029 28 12 0,000 0,03944996 0,07600651 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,03944996 0,07594661 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,03944996 0,07588681 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,03944996 0,07582711 ! oocyte differentiation GO:0009994 21 12 0,000 0,03944996 0,07576749 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,03944996 0,07570797 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,03944996 0,07564855 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,03944996 0,07558922 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,03944996 0,07552998 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,03944996 0,07547083 ! defense response to fungus GO:0050832 15 12 0,000 0,03944996 0,07541178 ! developmental induction GO:0031128 22 12 0,000 0,03944996 0,07535282 GO:0045168|cell-cell signaling involved in cell fate specification, ! response to cold GO:0009409 17 12 0,000 0,03944996 0,07529395 ! establishment of cell polarity GO:0030010 21 12 0,000 0,03944996 0,07523517 ! regulation of synapse organization GO:0050807 18 12 0,000 0,03944996 0,07517648 ! localization within membrane GO:0051668 26 12 0,000 0,03944996 0,07511789 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,03978694 0,07570054 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,04055552 0,07710283 ! regulation of T cell activation GO:0050863 175 96 1,000 0,04132971 0,07851359 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 0,04210946 0,07993273 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,04266693 0,08092804 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04266693 0,08086525 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,04266693 0,08080257 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04266693 0,08073998 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04266693 0,08067749 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,04266693 0,08061509 ! peroxisomal transport GO:0043574 28 13 0,000 0,04266693 0,08055279 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,04266693 0,08049059 ! cartilage condensation GO:0001502 22 13 0,000 0,04266693 0,08042848 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,04266693 0,08036647 ! organelle fusion GO:0048284 36 13 0,000 0,04266693 0,08030456 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,04266693 0,08024274 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,04266693 0,08018101 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,04266693 0,08011938 ! endocrine pancreas development GO:0031018 25 13 0,000 0,04266693 0,08005784 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,04266693 0,0799964 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,04266693 0,07993506 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,04266693 0,0798738 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,04266693 0,07981264 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,04266693 0,07975158 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04266693 0,07969061 ! methionine metabolic process GO:0006555 31 13 0,000 0,04266693 0,07962973 ! plasma membrane organization GO:0007009 27 13 0,000 0,04266693 0,07956894 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,04266693 0,07950825 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,04266693 0,07944765 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,04266693 0,07938714 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,04266693 0,07932672 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,04266693 0,0792664 ! cytokine metabolic process GO:0042107 24 13 0,000 0,04266693 0,07920617 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,04266693 0,07914602 ! exocrine system development GO:0035272 34 13 0,000 0,04266693 0,07908597 ! asymmetric protein localization GO:0008105 24 13 0,000 0,04266693 0,07902601 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,04266693 0,07896615 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,04266693 0,07890637 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,04266693 0,07884668 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,04266693 0,07878709 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,04266693 0,07872758 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,04266693 0,07866816 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,04266693 0,07860883 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,04266693 0,0785496 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,04266693 0,07849045 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,04266693 0,07843139 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,04266693 0,07837242 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04266693 0,07831353 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,04266693 0,07825474 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,04266693 0,07819603 ! histone methylation GO:0016571 29 13 0,000 0,04266693 0,07813742 ! chromatin silencing GO:0006342 29 13 0,000 0,04266693 0,07807889 ! gland morphogenesis GO:0022612 31 13 0,000 0,04266693 0,07802044 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,04266693 0,07796209 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,04266693 0,07790382 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04266693 0,07784564 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,04266693 0,07778755 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,04266693 0,07772954 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,04266693 0,07767162 ! spleen development GO:0048536 24 13 0,000 0,04266693 0,07761379 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,04266693 0,07755604 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,04266693 0,07749837 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,04266693 0,0774408 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,04266693 0,07738331 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,04266693 0,0773259 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04266693 0,07726858 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,04266693 0,07721134 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,04266693 0,07715419 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,04266693 0,07709713 ! insulin secretion GO:0030073 24 13 0,000 0,04266693 0,07704014 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,04266693 0,07698324 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,04266693 0,07692643 ! acrosome reaction GO:0007340 19 13 0,000 0,04266693 0,0768697 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,04266693 0,07681305 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,04266693 0,07675649 ! forebrain development GO:0030900 210 98 1,000 0,04289474 0,07710953 ! mRNA transport GO:0051028 185 100 1,000 0,04448168 0,0799035 ! rRNA transcription GO:0009303 28 14 0,000 0,04587322 0,0823426 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,04587322 0,08228214 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,04587322 0,08222177 ! water transport GO:0006833 21 14 0,000 0,04587322 0,08216149 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,04587322 0,0821013 ! non-recombinational repair GO:0000726 29 14 0,000 0,04587322 0,0820412 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,04587322 0,08198118 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,04587322 0,08192125 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,04587322 0,08186141 ! RNA polyadenylation GO:0043631 32 14 0,000 0,04587322 0,08180166 ! lipid localization GO:0010876 32 14 0,000 0,04587322 0,081742 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,04587322 0,08168242 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,04587322 0,08162293 ! regulated secretory pathway GO:0045055 24 14 0,000 0,04587322 0,08156352 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,04587322 0,0815042 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,04587322 0,08144497 ! arginine metabolic process GO:0006525 21 14 0,000 0,04587322 0,08138582 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,04587322 0,08132676 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,04587322 0,08126779 ! regulation of heart rate GO:0002027 25 14 0,000 0,04587322 0,0812089 ! fear response GO:0042596 34 14 0,000 0,04587322 0,08115009 ! organic alcohol transport GO:0015850 29 14 0,000 0,04587322 0,08109137 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,04587322 0,08103274 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,04587322 0,08097419 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04587322 0,08091572 ! neutral amino acid transport GO:0015804 28 14 0,000 0,04587322 0,08085734 ! bone mineralization GO:0030282 18 14 0,000 0,04587322 0,08079905 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,04587322 0,08074083 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,04587322 0,0806827 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,04587322 0,08062466 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,04587322 0,0805667 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,04587322 0,08050882 ! regulation of cellular pH GO:0030641 27 14 0,000 0,04587322 0,08045102 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,04587322 0,08039331 ! ribosome assembly GO:0042255 18 14 0,000 0,04587322 0,08033568 ! cerebellum development GO:0021549 23 14 0,000 0,04587322 0,08027813 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,04587322 0,08022067 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,04587322 0,08016329 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,04587322 0,08010599 ! response to gamma radiation GO:0010332 30 14 0,000 0,04587322 0,08004877 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,04587322 0,07999163 ! NADP metabolic process GO:0006739 24 14 0,000 0,04587322 0,07993458 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,04587322 0,0798776 ! oxygen transport GO:0015671 22 14 0,000 0,04587322 0,07982071 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04587322 0,0797639 ! male genitalia development GO:0030539 26 14 0,000 0,04587322 0,07970717 ! regulation of RNA stability GO:0043487 33 14 0,000 0,04587322 0,07965052 ! regulation of axon extension GO:0030516 43 14 0,000 0,04587322 0,07959395 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,04587322 0,07953746 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,04587322 0,07948105 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04906886 0,08495764 ! lactation GO:0007595 30 15 0,000 0,04906886 0,08489747 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,04906886 0,08483738 ! reproductive cellular process GO:0048610 22 15 0,000 0,04906886 0,08477739 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04906886 0,08471747 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,04906886 0,08465764 ! superoxide anion generation GO:0042554 22 15 0,000 0,04906886 0,0845979 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,04906886 0,08453824 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,04906886 0,08447866 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,04906886 0,08441917 ! copper ion transport GO:0006825 22 15 0,000 0,04906886 0,08435976 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,04906886 0,08430044 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,04906886 0,0842412 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,04906886 0,08418204 ! sulfate transport GO:0008272 27 15 0,000 0,04906886 0,08412296 ! response to cAMP GO:0051591 25 15 0,000 0,04906886 0,08406397 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,04906886 0,08400506 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,04906886 0,08394624 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,04906886 0,08388749 ! response to hexose stimulus GO:0009746 25 15 0,000 0,04906886 0,08382883 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,04906886 0,08377025 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,04906886 0,08371175 ! vesicle coating GO:0006901 38 15 0,000 0,04906886 0,08365333 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,04906886 0,083595 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,04906886 0,08353674 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,04906886 0,08347857 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,04906886 0,08342048 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,04906886 0,08336247 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,04906886 0,08330453 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,04906886 0,08324668 ! regulation of vasodilation GO:0042312 27 15 0,000 0,04906886 0,08318891 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,04906886 0,08313122 ! histone deacetylation GO:0016575 24 15 0,000 0,04906886 0,08307361 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04906886 0,08301608 ! water homeostasis GO:0030104 28 15 0,000 0,04906886 0,08295863 ! cofactor transport GO:0051181 30 15 0,000 0,04906886 0,08290126 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04906886 0,08284397 ! muscle maintenance GO:0046716 26 15 0,000 0,04906886 0,08278676 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,04906886 0,08272962 ! intestinal absorption GO:0050892 31 15 0,000 0,04906886 0,08267257 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04906886 0,08261559 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,04906886 0,08255869 ! heme biosynthetic process GO:0006783 33 15 0,000 0,04906886 0,08250188 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,04906886 0,08244513 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,04906886 0,08238847 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,04906886 0,08233189 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,04906886 0,08227538 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,04906886 0,08221895 ! actin filament polymerization GO:0030041 27 15 0,000 0,04906886 0,08216259 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,04906886 0,08210632 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,05225389 0,08737594 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,05225389 0,08731617 ! positive regulation of cell size GO:0045793 29 16 0,000 0,05225389 0,08725649 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,05225389 0,08719689 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,05225389 0,08713737 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,05225389 0,08707793 ! bone remodeling GO:0046849 28 16 0,000 0,05225389 0,08701857 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,05225389 0,08695929 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,05225389 0,0869001 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,05225389 0,08684098 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,05225389 0,08678195 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,05225389 0,08672299 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,05225389 0,08666412 ! startle response GO:0001964 28 16 0,000 0,05225389 0,08660532 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,05225389 0,08654661 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,05225389 0,08648797 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,05225389 0,08642941 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,05225389 0,08637094 ! protein polyubiquitination GO:0000209 41 16 0,000 0,05225389 0,08631254 ! glutamate metabolic process GO:0006536 25 16 0,000 0,05225389 0,08625422 ! response to osmotic stress GO:0006970 27 16 0,000 0,05225389 0,08619598 ! lysosomal transport GO:0007041 31 16 0,000 0,05225389 0,08613782 ! fructose metabolic process GO:0006000 25 16 0,000 0,05225389 0,08607973 ! L-amino acid transport GO:0015807 33 16 0,000 0,05225389 0,08602173 ! stem cell development GO:0048864 46 16 0,000 0,05225389 0,0859638 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05225389 0,08590595 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05225389 0,08584818 ! intermediate filament-based process GO:0045103 36 16 0,000 0,05225389 0,08579049 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,05225389 0,08573287 ! negative regulation of immune response GO:0050777 38 16 0,000 0,05225389 0,08567533 ! axon cargo transport GO:0008088 46 16 0,000 0,05225389 0,08561787 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,05225389 0,08556049 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,05225389 0,08550318 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,05225389 0,08544595 ! DNA replication initiation GO:0006270 28 16 0,000 0,05225389 0,08538879 ! neuron recognition GO:0008038 40 16 0,000 0,05225389 0,08533171 ! mRNA splice site selection GO:0006376 44 16 0,000 0,05225389 0,08527471 ! tissue regeneration GO:0042246 27 16 0,000 0,05225389 0,08521779 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,05225389 0,08516094 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,05225389 0,08510416 ! biomineral formation GO:0031214 22 16 0,000 0,05225389 0,08504746 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,05225389 0,08499084 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,05225389 0,08493429 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,05225389 0,08487782 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05225389 0,08482142 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,05225389 0,0847651 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,05225389 0,08470885 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,05225389 0,08465268 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,05225389 0,08459658 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,05225389 0,08454056 ! peptide hormone processing GO:0016486 27 16 0,000 0,05225389 0,08448461 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,05542833 0,08955782 ! metencephalon development GO:0022037 32 17 0,000 0,05542833 0,08949863 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,05542833 0,08943951 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,05542833 0,08938048 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,05542833 0,08932152 ! filopodium assembly GO:0046847 42 17 0,000 0,05542833 0,08926264 ! endothelial cell migration GO:0043542 31 17 0,000 0,05542833 0,08920383 ! gene silencing by RNA GO:0031047 38 17 0,000 0,05542833 0,08914511 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,05542833 0,08908646 ! glial cell development GO:0021782 28 17 0,000 0,05542833 0,08902789 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,05542833 0,0889694 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,05542833 0,08891098 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,05542833 0,08885264 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,05542833 0,08879437 ! myoblast differentiation GO:0045445 50 17 0,000 0,05542833 0,08873619 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,05542833 0,08867808 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,05542833 0,08862004 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,05542833 0,08856208 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,05542833 0,0885042 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,05542833 0,08844639 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,05542833 0,08838866 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,05542833 0,088331 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,05542833 0,08827342 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,05542833 0,08821591 ! membrane budding GO:0006900 42 17 0,000 0,05542833 0,08815848 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,05542833 0,08810112 ! regulation of protein binding GO:0043393 33 17 0,000 0,05542833 0,08804384 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,05542833 0,08798663 ! genitalia development GO:0048806 32 17 0,000 0,05542833 0,08792949 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,05542833 0,08787243 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,05542833 0,08781545 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,05542833 0,08775854 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,05542833 0,0877017 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,05542833 0,08764493 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,05542833 0,08758824 ! steroid catabolic process GO:0006706 34 17 0,000 0,05542833 0,08753162 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,05542833 0,08747508 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,05542833 0,08741861 ! gas transport GO:0015669 26 17 0,000 0,05542833 0,08736221 ! organic cation transport GO:0015695 32 17 0,000 0,05542833 0,08730588 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,05542833 0,08724963 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,05542833 0,08719345 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,05542833 0,08713734 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,05859224 0,09205199 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,05859224 0,09199283 ! limbic system development GO:0021761 40 18 0,000 0,05859224 0,09193374 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05859224 0,09187474 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,05859224 0,0918158 ! adult walking behavior GO:0007628 36 18 0,000 0,05859224 0,09175695 ! patterning of blood vessels GO:0001569 43 18 0,000 0,05859224 0,09169817 ! heart looping GO:0001947 34 18 0,000 0,05859224 0,09163946 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,05859224 0,09158083 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,05859224 0,09152228 ! centrosome cycle GO:0007098 26 18 0,000 0,05859224 0,09146379 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,05859224 0,09140539 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,05859224 0,09134706 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,05859224 0,0912888 ! glycine metabolic process GO:0006544 30 18 0,000 0,05859224 0,09123062 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05859224 0,09117251 ! response to retinoic acid GO:0032526 31 18 0,000 0,05859224 0,09111447 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,05859224 0,09105651 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,05859224 0,09099863 ! DNA integration GO:0015074 32 18 0,000 0,05859224 0,09094081 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,05859224 0,09088307 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,05859224 0,09082541 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,05859224 0,09076781 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,05859224 0,09071029 ! neural crest cell migration GO:0001755 41 18 0,000 0,05859224 0,09065284 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,05859224 0,09059547 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,05859224 0,09053817 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,05859224 0,09048093 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,05859224 0,09042378 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,05859224 0,09036669 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,05859224 0,09030968 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,05859224 0,09025274 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,05859224 0,09019587 ! detection of bacterium GO:0016045 22 18 0,000 0,05859224 0,09013907 ! nerve development GO:0021675 34 18 0,000 0,05859224 0,09008234 ! microspike assembly GO:0030035 46 18 0,000 0,05859224 0,09002568 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,05859224 0,0899691 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,05859224 0,08991259 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,06174563 0,09469214 ! positive regulation of translation GO:0045727 31 19 0,000 0,06174563 0,09463274 ! negative regulation of defense response GO:0031348 27 19 0,000 0,06174563 0,09457341 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,06174563 0,09451415 ! neuron maturation GO:0042551 46 19 0,000 0,06174563 0,09445497 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,06174563 0,09439586 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,06174563 0,09433683 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,06174563 0,09427786 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,06174563 0,09421898 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,06174563 0,09416016 ! inositol metabolic process GO:0006020 33 19 0,000 0,06174563 0,09410142 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,06174563 0,09404276 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,06174563 0,09398416 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,06174563 0,09392564 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,06174563 0,0938672 ! cerebral cortex development GO:0021987 40 19 0,000 0,06174563 0,09380882 ! pigmentation during development GO:0048066 42 19 0,000 0,06174563 0,09375052 ! response to vitamin A GO:0033189 32 19 0,000 0,06174563 0,09369229 ! heme metabolic process GO:0042168 40 19 0,000 0,06174563 0,09363413 ! neuromuscular junction development GO:0007528 43 19 0,000 0,06174563 0,09357604 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,06174563 0,09351803 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,06174563 0,09346009 ! response to fungus GO:0009620 26 19 0,000 0,06174563 0,09340222 ! protein export from nucleus GO:0006611 40 19 0,000 0,06174563 0,09334442 ! heart process GO:0003015 32 19 0,000 0,06174563 0,09328669 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,06174563 0,09322904 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,06174563 0,09317145 ! visual learning GO:0008542 38 19 0,000 0,06174563 0,09311394 ! cellular pigmentation GO:0033059 37 19 0,000 0,06174563 0,0930565 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,06174563 0,09299913 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,06174563 0,09294183 ! vitamin transport GO:0051180 31 19 0,000 0,06174563 0,0928846 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,06174563 0,09282744 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,06174563 0,09277035 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,06174563 0,09271333 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,06174563 0,09265638 ! cilium assembly GO:0042384 38 19 0,000 0,06174563 0,0925995 ! peptide hormone secretion GO:0030072 32 19 0,000 0,06174563 0,09254269 ! protein secretion GO:0009306 45 20 0,000 0,06488856 0,09719359 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,06488856 0,09713403 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,06488856 0,09707455 ! positive regulation of ossification GO:0045778 50 20 0,000 0,06488856 0,09701514 ! skin development GO:0043588 42 20 0,000 0,06488856 0,0969558 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,06488856 0,09689654 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,06488856 0,09683735 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,06488856 0,09677823 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,06488856 0,09671918 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,06488856 0,09666021 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,06488856 0,0966013 ! response to vitamin GO:0033273 36 20 0,000 0,06488856 0,09654247 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,06488856 0,09648371 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,06488856 0,09642502 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,06488856 0,09636641 ! bile acid metabolic process GO:0008206 34 20 0,000 0,06488856 0,09630786 ! response to alkaloid GO:0043279 38 20 0,000 0,06488856 0,09624939 ! retinoid metabolic process GO:0001523 34 20 0,000 0,06488856 0,09619098 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,06488856 0,09613265 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,06488856 0,09607439 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,06488856 0,0960162 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,06488856 0,09595808 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,06488856 0,09590002 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,06488856 0,09584204 ! actin filament bundle formation GO:0051017 47 20 0,000 0,06488856 0,09578413 ! body fluid secretion GO:0007589 33 20 0,000 0,06488856 0,09572629 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,06488856 0,09566852 ! peptide secretion GO:0002790 38 20 0,000 0,06488856 0,09561082 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,06488856 0,09555319 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,06488856 0,09549563 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,06488856 0,09543813 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,06488856 0,09538071 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,06488856 0,09532336 ! cell-cell junction organization GO:0045216 43 20 0,000 0,06488856 0,09526607 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,06488856 0,09520885 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,06488856 0,0951517 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,06488856 0,09509463 ! regulation of glucose import GO:0046324 30 20 0,000 0,06488856 0,09503761 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,06488856 0,09498067 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,06488856 0,0949238 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,06488856 0,09486699 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,06488856 0,09481025 ! regulation of cell killing GO:0031341 46 21 0,000 0,06802104 0,09932779 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,06802104 0,09926845 ! hormone secretion GO:0046879 39 21 0,000 0,06802104 0,09920919 ! lipid phosphorylation GO:0046834 43 21 0,000 0,06802104 0,09914999 ! cAMP metabolic process GO:0046058 41 21 0,000 0,06802104 0,09909087 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,06802104 0,09903182 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,06802104 0,09897284 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,06802104 0,09891392 ! ovarian follicle development GO:0001541 39 21 0,000 0,06802104 0,09885508 ! smooth muscle contraction GO:0006939 48 21 0,000 0,06802104 0,09879631 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,06802104 0,09873761 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,06802104 0,09867897 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,06802104 0,09862041 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,06802104 0,09856192 ! plasma membrane fusion GO:0045026 33 21 0,000 0,06802104 0,09850349 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,06802104 0,09844514 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,06802104 0,09838685 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,06802104 0,09832863 ! sensory perception of pain GO:0019233 33 21 0,000 0,06802104 0,09827049 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,06802104 0,09821241 ! collagen fibril organization GO:0030199 62 21 0,000 0,06802104 0,0981544 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,06802104 0,09809645 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,06802104 0,09803858 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,06802104 0,09798077 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,06802104 0,09792304 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,06802104 0,09786537 ! collagen catabolic process GO:0030574 29 21 0,000 0,06802104 0,09780776 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,06802104 0,09775023 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,06802104 0,09769276 ! sperm-egg recognition GO:0035036 23 21 0,000 0,06802104 0,09763537 ! actin filament-based movement GO:0030048 47 21 0,000 0,06802104 0,09757803 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,06802104 0,09752077 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,07114311 0,10193702 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,07114311 0,10187727 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,07114311 0,10181759 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,07114311 0,10175798 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,07114311 0,10169843 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,07114311 0,10163896 ! microtubule-based transport GO:0010970 59 22 0,000 0,07114311 0,10157956 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,07114311 0,10152022 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,07114311 0,10146096 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,07114311 0,10140176 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,07114311 0,10134264 ! vacuolar transport GO:0007034 41 22 0,000 0,07114311 0,10128358 ! central nervous system neuron development GO:0021954 47 22 0,000 0,07114311 0,10122459 ! fucose metabolic process GO:0006004 44 22 0,000 0,07114311 0,10116567 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,07114311 0,10110682 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,07114311 0,10104804 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,07114311 0,10098932 ! ureteric bud development GO:0001657 50 22 0,000 0,07114311 0,10093068 ! cell aging GO:0007569 48 22 0,000 0,07114311 0,1008721 ! stem cell differentiation GO:0048863 57 22 0,000 0,07114311 0,10081359 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,07114311 0,10075514 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,07114311 0,10069677 ! cytolysis GO:0019835 27 22 0,000 0,07114311 0,10063846 ! renal system process GO:0003014 42 22 0,000 0,07114311 0,10058022 ! vasodilation GO:0042311 40 22 0,000 0,07114311 0,10052205 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,07114311 0,10046394 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,07114311 0,10040591 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,07114311 0,10034793 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,07114311 0,10029003 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,07114311 0,10023219 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,07114311 0,10017442 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,07114311 0,10011672 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,07114311 0,10005908 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,07114311 0,10000151 ! sarcomere organization GO:0045214 32 22 0,000 0,07114311 0,099944 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,07114311 0,09988656 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,07114311 0,09982919 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,07114311 0,09977188 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,07114311 0,09971464 ! gut development GO:0048565 44 22 0,000 0,07114311 0,09965747 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,07114311 0,09960036 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,07114311 0,09954331 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,07114311 0,09948633 ! protein stabilization GO:0050821 41 22 0,000 0,07114311 0,09942942 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,07425482 0,10371899 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,07425482 0,10365972 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,07425482 0,10360052 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,07425482 0,10354139 ! glycerol metabolic process GO:0006071 40 23 0,000 0,07425482 0,10348233 ! viral genome replication GO:0019079 44 23 0,000 0,07425482 0,10342333 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,07425482 0,1033644 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,07425482 0,10330553 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,07425482 0,10324674 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,07425482 0,10318801 ! regeneration GO:0031099 42 23 0,000 0,07425482 0,10312934 ! axis specification GO:0009798 43 23 0,000 0,07425482 0,10307075 ! visual behavior GO:0007632 46 23 0,000 0,07425482 0,10301222 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,07425482 0,10295376 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 47 23 0,000 0,07425482 0,10289536 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,07425482 0,10283703 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,07425482 0,10277876 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,07425482 0,10272056 ! peroxisome organization GO:0007031 43 23 0,000 0,07425482 0,10266243 ! lysosome organization GO:0007040 47 23 0,000 0,07425482 0,10260436 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,07425482 0,10254636 ! vesicle targeting GO:0006903 49 23 0,000 0,07425482 0,10248843 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,07425482 0,10243056 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,07425482 0,10237275 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,07425482 0,10231501 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,07425482 0,10225734 ! DNA modification GO:0006304 36 23 0,000 0,07425482 0,10219973 ! fatty acid transport GO:0015908 47 23 0,000 0,07425482 0,10214218 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,07425482 0,1020847 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,07425482 0,10202729 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,07425482 0,10196994 ! hormone transport GO:0009914 41 23 0,000 0,07425482 0,10191265 ! cell-cell recognition GO:0009988 28 23 0,000 0,07425482 0,10185543 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,07425482 0,10179827 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,07425482 0,10174118 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,07425482 0,10168415 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,07735618 0,1058718 ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,07735618 0,10581252 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,07735618 0,10575331 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,07735618 0,10569416 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,07735618 0,10563508 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,07735618 0,10557607 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,07735618 0,10551712 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,07735618 0,10545824 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,07735618 0,10539942 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,07735618 0,10534067 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,07735618 0,10528198 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,07735618 0,10522336 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,07735618 0,10516481 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,07735618 0,10510632 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,07735618 0,10504789 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,07735618 0,10498953 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,07735618 0,10493124 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,07735618 0,10487301 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,07735618 0,10481484 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,07735618 0,10475674 ! membrane depolarization GO:0051899 45 24 0,000 0,07735618 0,1046987 ! pallium development GO:0021543 56 24 0,000 0,07735618 0,10464073 ! oogenesis GO:0048477 44 24 0,000 0,07735618 0,10458282 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,07735618 0,10452498 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,07735618 0,1044672 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,07735618 0,10440948 ! platelet activation GO:0030168 41 24 0,000 0,07735618 0,10435183 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,07735618 0,10429424 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,07735618 0,10423671 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,07735618 0,10417925 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,07735618 0,10412185 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,07735618 0,10406451 ! regulation of amine transport GO:0051952 41 24 0,000 0,07735618 0,10400724 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,07735618 0,10395003 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,08044725 0,10804433 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,08044725 0,10798496 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,08044725 0,10792566 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,08044725 0,10786643 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,08044725 0,10780726 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,08044725 0,10774815 ! phototransduction GO:0007602 37 25 0,000 0,08044725 0,10768911 ! vasculogenesis GO:0001570 49 25 0,000 0,08044725 0,10763014 ! vacuole organization GO:0007033 49 25 0,000 0,08044725 0,10757123 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,08044725 0,10751238 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,08044725 0,1074536 ! receptor metabolic process GO:0043112 53 25 0,000 0,08044725 0,10739488 ! chromosome condensation GO:0030261 48 25 0,000 0,08044725 0,10733623 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,08044725 0,10727764 ! regulation of behavior GO:0050795 48 25 0,000 0,08044725 0,10721911 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,08044725 0,10716065 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,08044725 0,10710225 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,08044725 0,10704392 ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,08044725 0,10698564 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,08044725 0,10692744 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,08044725 0,10686929 ! liver development GO:0001889 55 25 0,000 0,08044725 0,10681121 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,08352804 0,1108414 ! myelination GO:0042552 50 26 0,000 0,08352804 0,11078122 ! initiation of viral infection GO:0019059 60 26 0,000 0,08352804 0,11072111 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,08352804 0,11066107 ! molting cycle process GO:0022404 52 26 0,000 0,08352804 0,11060109 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,08352804 0,11054118 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,08352804 0,11048133 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,08352804 0,11042154 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,08352804 0,11036182 GO:0051297|centrosome organization, ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,08352804 0,11030217 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,08352804 0,11024258 ! digestive system process GO:0022600 49 26 0,000 0,08352804 0,11018305 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,08352804 0,11012359 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,08352804 0,11006419 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,08352804 0,11000486 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,08352804 0,10994559 ! osteoblast differentiation GO:0001649 63 26 0,000 0,08352804 0,10988638 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,08352804 0,10982724 ! neural crest cell development GO:0014032 59 26 0,000 0,08352804 0,10976816 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,08352804 0,10970915 ! negative regulation of cell development GO:0010721 83 26 0,000 0,08352804 0,10965019 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,08352804 0,10959131 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,08352804 0,10953248 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,08352804 0,10947372 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,08352804 0,10941502 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,08352804 0,10935638 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,08352804 0,10929781 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,08352804 0,1092393 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,08352804 0,10918085 ! blastocyst development GO:0001824 50 26 0,000 0,08352804 0,10912247 ! telomere organization GO:0032200 46 26 0,000 0,08352804 0,10906414 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,08352804 0,10900588 ! neural tube closure GO:0001843 58 26 0,000 0,08352804 0,10894768 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,08352804 0,10888955 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,08352804 0,10883147 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,08352804 0,10877346 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,0865986 0,11271198 ! embryonic pattern specification GO:0009880 49 27 0,000 0,0865986 0,11265197 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,0865986 0,11259201 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,0865986 0,11253212 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,0865986 0,1124723 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,0865986 0,11241254 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,0865986 0,11235284 ! iron ion transport GO:0006826 65 27 0,000 0,0865986 0,1122932 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,0865986 0,11223363 ! superoxide metabolic process GO:0006801 41 27 0,000 0,0865986 0,11217412 ! tube lumen formation GO:0035148 59 27 0,000 0,0865986 0,11211467 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,0865986 0,11205529 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,0865986 0,11199597 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,0865986 0,11193671 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,0865986 0,11187752 ! response to toxin GO:0009636 49 27 0,000 0,0865986 0,11181839 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,0865986 0,11175932 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,0865986 0,11170031 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,0865986 0,11164137 ! leukocyte proliferation GO:0070661 59 27 0,000 0,0865986 0,11158248 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,0865986 0,11152366 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,08965896 0,11540403 ! neuron fate commitment GO:0048663 52 28 0,000 0,08965896 0,11534326 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,08965896 0,11528255 ! protein amino acid acylation GO:0043543 59 28 0,000 0,08965896 0,11522191 ! vesicle docking GO:0048278 55 28 0,000 0,08965896 0,11516133 ! circadian rhythm GO:0007623 56 28 0,000 0,08965896 0,11510081 ! dendrite development GO:0016358 67 28 0,000 0,08965896 0,11504036 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,08965896 0,11497997 ! fat cell differentiation GO:0045444 57 28 0,000 0,08965896 0,11491965 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,08965896 0,11485939 ! sperm motility GO:0030317 37 28 0,000 0,08965896 0,11479919 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,08965896 0,11473905 ! base-excision repair GO:0006284 41 28 0,000 0,08965896 0,11467898 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,08965896 0,11461897 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,08965896 0,11455902 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,08965896 0,11449914 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,08965896 0,11443931 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,08965896 0,11437955 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,08965896 0,11431986 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,08965896 0,11426022 ! glutathione metabolic process GO:0006749 42 28 0,000 0,08965896 0,11420065 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,08965896 0,11414114 ! lipid oxidation GO:0034440 48 28 0,000 0,08965896 0,11408169 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,08965896 0,1140223 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,08965896 0,11396298 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,09270915 0,11777871 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,09270915 0,1177175 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,09270915 0,11765635 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,09270915 0,11759526 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,09270915 0,11753423 ! autophagy GO:0006914 47 29 0,000 0,09270915 0,11747327 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,09270915 0,11741237 ! primary neural tube formation GO:0014020 61 29 0,000 0,09270915 0,11735154 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,09270915 0,11729076 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,09270915 0,11723005 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,09270915 0,11716941 ! somitogenesis GO:0001756 52 29 0,000 0,09270915 0,11710882 ! synaptogenesis GO:0007416 46 29 0,000 0,09270915 0,1170483 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,09270915 0,11698784 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,09270915 0,11692745 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,09270915 0,11686711 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,09270915 0,11680684 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,09574921 0,12057491 ! phenol metabolic process GO:0018958 56 30 0,000 0,09574921 0,12051279 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,09574921 0,12045073 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,09574921 0,12038874 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,09574921 0,12032681 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,09574921 0,12026495 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,09574921 0,12020315 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,09574921 0,12014141 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,09574921 0,12007973 ! myofibril assembly GO:0030239 50 30 0,000 0,09574921 0,12001812 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,09574921 0,11995658 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,09574921 0,11989509 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,09574921 0,11983367 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,09574921 0,11977231 ! phospholipid transport GO:0015914 65 30 0,000 0,09574921 0,11971101 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,09574921 0,11964978 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,09574921 0,11958861 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,09574921 0,1195275 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,09574921 0,11946646 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,09574921 0,11940547 ! regulation of coagulation GO:0050818 52 30 0,000 0,09574921 0,11934455 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,09877917 0,12305839 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,09877917 0,12299567 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,09877917 0,12293301 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,09877917 0,12287042 ! regulation of innate immune response GO:0045088 57 31 0,000 0,09877917 0,12280789 ! ovulation cycle process GO:0022602 55 31 0,000 0,09877917 0,12274542 ! peptide transport GO:0015833 60 31 0,000 0,09877917 0,12268302 ! male gonad development GO:0008584 56 31 0,000 0,09877917 0,12262068 ! iron ion homeostasis GO:0055072 60 31 0,000 0,09877917 0,12255841 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,09877917 0,1224962 ! detection of light stimulus GO:0009583 44 31 0,000 0,09877917 0,12243405 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,09877917 0,12237196 ! natural killer cell activation GO:0030101 50 31 0,000 0,09877917 0,12230994 ! ensheathment of neurons GO:0007272 64 31 0,000 0,09877917 0,12224798 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,09877917 0,12218608 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,09877917 0,12212424 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,09877917 0,12206247 ! eye morphogenesis GO:0048592 65 31 0,000 0,09877917 0,12200076 ! response to heat GO:0009408 54 31 0,000 0,09877917 0,12193911 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,09877917 0,12187753 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,10179905 0,12554018 ! collagen metabolic process GO:0032963 49 32 0,000 0,10179905 0,12547684 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,10179905 0,12541356 ! spindle organization GO:0007051 50 32 0,000 0,10179905 0,12535035 ! metanephros development GO:0001656 81 32 0,000 0,10179905 0,1252872 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,10179905 0,12522411 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,10179905 0,12516109 ! muscle cell development GO:0055001 52 32 0,000 0,10179905 0,12509813 ! mesoderm formation GO:0001707 73 32 0,000 0,10179905 0,12503524 ! ovulation cycle GO:0042698 57 32 0,000 0,10179905 0,12497241 ! peripheral nervous system development GO:0007422 68 32 0,000 0,10179905 0,12490964 ! BMP signaling pathway GO:0030509 71 32 0,000 0,10179905 0,12484693 ! hindbrain development GO:0030902 65 32 0,000 0,10179905 0,12478429 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,10179905 0,12472171 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,10179905 0,12465919 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,10179905 0,12459674 ! gene silencing GO:0016458 71 32 0,000 0,10179905 0,12453435 ! regulation of pH GO:0006885 56 33 0,000 0,10480891 0,12815223 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,10480891 0,12808813 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,10480891 0,12802408 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,10480891 0,1279601 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,10480891 0,12789618 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,10480891 0,12783233 ! response to ionizing radiation GO:0010212 74 33 0,000 0,10480891 0,12776854 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,10480891 0,12770482 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,10480891 0,12764116 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,10480891 0,12757756 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,10480891 0,12751402 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,10480891 0,12745055 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,10480891 0,12738715 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,10480891 0,1273238 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,10780876 0,13090298 ! glial cell differentiation GO:0010001 67 34 0,000 0,10780876 0,13083795 ! post-embryonic development GO:0009791 76 34 0,000 0,10780876 0,13077299 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,10780876 0,13070809 ! cholesterol transport GO:0030301 62 34 0,000 0,10780876 0,13064325 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,10780876 0,13057848 ! spliceosome assembly GO:0000245 75 34 0,000 0,10780876 0,13051378 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,10780876 0,13044913 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,10780876 0,13038455 ! formation of primary germ layer GO:0001704 76 34 0,000 0,10780876 0,13032004 ! cell fate specification GO:0001708 56 34 0,000 0,10780876 0,13025559 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,10780876 0,1301912 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,10780876 0,13012688 ! adult locomotory behavior GO:0008344 62 34 0,000 0,10780876 0,13006262 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,11079864 0,13360369 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,11079864 0,13353778 ! negative regulation of secretion GO:0051048 68 35 0,000 0,11079864 0,13347194 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,11079864 0,13340615 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,11079864 0,13334044 ! membrane docking GO:0022406 69 35 0,000 0,11079864 0,13327478 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,11079864 0,1332092 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,11079864 0,13314367 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,11079864 0,13307821 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,11079864 0,13301282 ! ceramide metabolic process GO:0006672 72 35 0,000 0,11079864 0,13294749 ! telencephalon development GO:0021537 81 35 0,000 0,11079864 0,13288222 ! sterol transport GO:0015918 63 35 0,000 0,11079864 0,13281702 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,11079864 0,13275188 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,11079864 0,13268681 ! vesicle localization GO:0051648 70 35 0,000 0,11079864 0,1326218 ! regulation of muscle development GO:0048634 82 36 0,000 0,11377859 0,13612199 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,11377859 0,13605536 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,11377859 0,1359888 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,11377859 0,1359223 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,11377859 0,13585586 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,11377859 0,1357895 ! positive regulation of cell development GO:0010720 85 36 0,000 0,11377859 0,13572319 ! protein targeting to membrane GO:0006612 75 36 0,000 0,11377859 0,13565695 ! regulation of proteolysis GO:0030162 77 36 0,000 0,11377859 0,13559078 ! aerobic respiration GO:0009060 56 36 0,000 0,11377859 0,13552467 ! cytokine production GO:0001816 68 36 0,000 0,11377859 0,13545862 ! embryonic organ development GO:0048568 67 36 0,000 0,11377859 0,13539264 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,11377859 0,13532673 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,11674864 0,13879169 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,11674864 0,13872418 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,11674864 0,13865674 ! sister chromatid segregation GO:0000819 65 37 0,000 0,11674864 0,13858937 ! odontogenesis GO:0042476 74 37 0,000 0,11674864 0,13852206 ! actomyosin structure organization GO:0031032 68 37 0,000 0,11674864 0,13845481 ! tissue remodeling GO:0048771 78 37 0,000 0,11674864 0,13838764 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,11674864 0,13832052 ! female gonad development GO:0008585 71 37 0,000 0,11674864 0,13825347 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,11674864 0,13818649 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,11674864 0,13811957 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,11674864 0,13805272 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,11674864 0,13798593 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,11970881 0,14141616 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,11970881 0,14134781 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,11970881 0,14127953 ! organic anion transport GO:0015711 82 38 0,000 0,11970881 0,14121131 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,11970881 0,14114316 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,11970881 0,14107507 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,11970881 0,14100705 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,11970881 0,1409391 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,11970881 0,14087121 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,11970881 0,14080338 ! regulation of protein stability GO:0031647 77 38 0,000 0,11970881 0,14073562 ! spermatid development GO:0007286 69 38 0,000 0,11970881 0,14066793 ! glycogen metabolic process GO:0005977 63 38 0,000 0,11970881 0,1406003 ! pigment metabolic process GO:0042440 87 38 0,000 0,11970881 0,14053274 ! neural tube formation GO:0001841 79 38 0,000 0,11970881 0,14046524 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,12265915 0,14385804 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,12265915 0,14378901 ! negative regulation of binding GO:0051100 71 39 0,000 0,12265915 0,14372005 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,12265915 0,14365115 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,12265915 0,14358232 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,12265915 0,14351355 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,12265915 0,14344485 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,12265915 0,14337622 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,12265915 0,14330765 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,12265915 0,14323915 ! glucan metabolic process GO:0044042 64 39 0,000 0,12265915 0,14317071 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 0,000 0,12559968 0,14653296 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,12559968 0,14646301 ! learning GO:0007612 82 40 0,000 0,12559968 0,14639314 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,12559968 0,14632333 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,12559968 0,14625358 ! lipid homeostasis GO:0055088 75 40 0,000 0,12559968 0,1461839 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,12559968 0,14611429 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,12559968 0,14604475 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,12559968 0,14597527 ! RNA export from nucleus GO:0006405 61 41 0,000 0,12853044 0,14931044 ! mRNA catabolic process GO:0006402 79 41 0,000 0,12853044 0,14923947 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,12853044 0,14916858 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,12853044 0,14909775 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,12853044 0,14902698 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,12853044 0,14895629 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,12853044 0,14888566 ! gliogenesis GO:0042063 91 41 0,000 0,12853044 0,1488151 ! feeding behavior GO:0007631 69 41 0,000 0,12853044 0,1487446 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,12853044 0,14867417 ! mesenchymal cell development GO:0014031 94 41 0,000 0,12853044 0,14860381 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,12853044 0,14853352 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,12853044 0,14846329 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,12853044 0,14839313 ! spermatid differentiation GO:0048515 73 41 0,000 0,12853044 0,14832303 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,12853044 0,148253 ! RNA modification GO:0009451 64 41 0,000 0,12853044 0,14818304 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,13145145 0,1514792 ! ear morphogenesis GO:0042471 64 42 0,000 0,13145145 0,15140778 ! organic ether metabolic process GO:0018904 59 42 0,000 0,13145145 0,15133643 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,13145145 0,15126514 ! T cell differentiation GO:0030217 93 42 0,000 0,13145145 0,15119393 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,13145145 0,15112278 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,13145145 0,15105169 ! regulation of protein secretion GO:0050708 77 42 0,000 0,13145145 0,15098068 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,13145145 0,15090973 ! cytokinesis GO:0000910 84 42 0,000 0,13145145 0,15083884 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,13145145 0,15076803 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,13436276 0,15403483 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,13436276 0,15396258 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,13436276 0,1538904 ! regulation of tube size GO:0035150 76 43 0,000 0,13436276 0,15381829 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,13436276 0,15374624 ! glucose transport GO:0015758 66 43 0,000 0,13436276 0,15367426 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,13436276 0,15360235 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,13436276 0,15353051 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,13436276 0,15345873 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,13436276 0,15338702 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,13436276 0,15331538 ! segmentation GO:0035282 78 43 0,000 0,13436276 0,1532438 ! ion transmembrane transport GO:0034220 79 43 0,000 0,13436276 0,15317229 ! neuron migration GO:0001764 85 43 0,000 0,13436276 0,15310085 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,13726439 0,15633423 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,13726439 0,15626138 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,13726439 0,1561886 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,13726439 0,15611588 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,13726439 0,15604324 ! hexose transport GO:0008645 68 44 0,000 0,13726439 0,15597066 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,13726439 0,15589815 ! striated muscle contraction GO:0006941 85 44 0,000 0,13726439 0,1558257 ! phagocytosis GO:0006909 105 44 0,000 0,13726439 0,15575333 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,13726439 0,15568102 ! double-strand break repair GO:0006302 85 44 0,000 0,13726439 0,15560878 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,14015638 0,15881356 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,14015638 0,15873993 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,14015638 0,15866638 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,14015638 0,15859288 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,14015638 0,15851946 ! B cell differentiation GO:0030183 124 45 0,000 0,14015638 0,15844611 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,14015638 0,15837282 ! female gamete generation GO:0007292 71 45 0,000 0,14015638 0,1582996 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,14015638 0,15822645 ! polyol metabolic process GO:0019751 77 45 0,000 0,14015638 0,15815337 ! developmental growth GO:0048589 88 45 0,000 0,14015638 0,15808035 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,14303875 0,16125689 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 0,000 0,14303875 0,16118251 ! glycolysis GO:0006096 71 46 0,000 0,14303875 0,1611082 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,14303875 0,16103395 ! leukocyte migration GO:0050900 75 46 0,000 0,14303875 0,16095978 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,14303875 0,16088567 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,14303875 0,16081163 ! pigmentation GO:0043473 103 46 0,000 0,14303875 0,16073766 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,14303875 0,16066376 ! neural tube development GO:0021915 91 47 0,000 0,14591155 0,16381522 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,14591155 0,16373997 ! positive regulation of cell cycle GO:0045787 96 48 0,000 0,14877479 0,16687641 ! positive regulation of defense response GO:0031349 88 48 0,000 0,14877479 0,16679982 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,14877479 0,16672331 ! mitochondrial transport GO:0006839 94 48 0,000 0,14877479 0,16664686 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,14877479 0,16657049 ! cellular component disassembly GO:0022411 89 48 0,000 0,14877479 0,16649419 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,14877479 0,16641795 ! endosome transport GO:0016197 127 48 0,000 0,14877479 0,16634179 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,14877479 0,1662657 ! male sex differentiation GO:0046661 93 48 0,000 0,14877479 0,16618967 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,14877479 0,16611372 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,14877479 0,16603783 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,14877479 0,16596201 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,14877479 0,16588627 ! methylation GO:0032259 97 48 0,000 0,14877479 0,16581059 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,15162851 0,16891403 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,15162851 0,16883704 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,15162851 0,16876012 ! JNK cascade GO:0007254 106 49 0,000 0,15162851 0,16868327 ! regulation of action potential GO:0001508 102 50 0,000 0,15447275 0,1717692 ! regulation of ion transport GO:0043269 86 50 0,000 0,15447275 0,17169105 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,15447275 0,17161297 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,15447275 0,17153497 ! activation of caspase activity GO:0006919 95 50 0,000 0,15447275 0,17145703 ! regulation of ossification GO:0030278 123 50 0,000 0,15447275 0,17137917 ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,15447275 0,17130138 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,15447275 0,17122365 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,15447275 0,171146 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,15730753 0,17420775 ! viral infectious cycle GO:0019058 104 51 0,000 0,15730753 0,17412882 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,15730753 0,17404996 ! peptide metabolic process GO:0006518 80 51 0,000 0,15730753 0,17397117 ! response to temperature stimulus GO:0009266 84 51 0,000 0,15730753 0,17389245 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,15730753 0,1738138 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,15730753 0,17373522 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,16013289 0,17677571 ! Notch signaling pathway GO:0007219 111 52 0,000 0,16013289 0,17669587 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,16013289 0,1766161 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,16013289 0,1765364 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,16013289 0,17645677 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,16013289 0,17637721 ! excretion GO:0007588 87 52 0,000 0,16013289 0,17629772 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,16013289 0,17621831 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,16013289 0,17613897 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,16013289 0,1760597 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,16013289 0,1759805 ! amino acid activation GO:0043038 98 52 0,000 0,16013289 0,17590137 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,16294885 0,17891418 ! positive regulation of growth GO:0045927 96 53 0,000 0,16294885 0,17883381 ! inner ear development GO:0048839 89 53 0,000 0,16294885 0,1787535 ! chromatin remodeling GO:0006338 122 53 0,000 0,16294885 0,17867327 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,16294885 0,17859311 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,16294885 0,17851303 ! vesicle organization GO:0016050 127 53 0,000 0,16294885 0,17843301 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,16294885 0,17835307 ! cartilage development GO:0051216 99 53 0,000 0,16294885 0,1782732 ! synapse organization GO:0050808 102 53 0,000 0,16294885 0,1781934 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,16575546 0,18118147 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,16575546 0,18110044 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,16575546 0,18101948 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,16575546 0,1809386 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,16575546 0,18085778 ! membrane fusion GO:0006944 122 54 0,000 0,16575546 0,18077704 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,16575546 0,18069638 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,16575546 0,18061578 ! RNA catabolic process GO:0006401 103 55 0,000 0,16855273 0,18358195 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,16855273 0,18350014 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,16855273 0,1834184 ! cell recognition GO:0008037 98 55 0,000 0,16855273 0,18333674 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,16855273 0,18325514 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,17134069 0,18620343 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,17134069 0,18612064 ! glucose catabolic process GO:0006007 88 56 0,000 0,17134069 0,18603792 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,17134069 0,18595527 ! regulation of DNA replication GO:0006275 105 56 0,000 0,17134069 0,1858727 ! RNA elongation GO:0006354 90 56 0,000 0,17134069 0,1857902 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 0,000 0,17411939 0,18871947 ! chloride transport GO:0006821 102 57 0,000 0,17411939 0,18863578 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,17411939 0,18855216 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,17411939 0,18846862 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,17411939 0,18838515 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,17411939 0,18830176 ! heart morphogenesis GO:0003007 105 57 0,000 0,17411939 0,18821844 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,17411939 0,1881352 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,17411939 0,18805202 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,17688885 0,19095867 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,17688885 0,19087432 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,17688885 0,19079005 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,17688885 0,19070585 ! gastrulation GO:0007369 122 58 0,000 0,17688885 0,19062173 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,17688885 0,19053768 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,17688885 0,19045371 ! nuclear export GO:0051168 110 59 0,000 0,1796491 0,19334042 ! establishment of organelle localization GO:0051656 122 59 0,000 0,1796491 0,19325529 ! lipid modification GO:0030258 112 60 0,000 0,18240017 0,19612835 ! DNA catabolic process GO:0006308 94 60 0,000 0,18240017 0,19604207 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,18240017 0,19595586 ! adult behavior GO:0030534 104 60 0,000 0,18240017 0,19586972 ! positive regulation of secretion GO:0051047 110 61 0,000 0,1851421 0,19872677 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,1851421 0,1986395 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,1851421 0,1985523 ! regulation of heart contraction GO:0008016 123 61 0,000 0,1851421 0,19846518 ! camera-type eye development GO:0043010 126 61 0,000 0,1851421 0,19837813 ! proton transport GO:0015992 117 61 0,000 0,1851421 0,19829116 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,1851421 0,19820427 ! viral reproductive process GO:0022415 132 62 0,000 0,1878749 0,20104178 ! tRNA processing GO:0008033 102 62 0,000 0,1878749 0,20095376 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,1878749 0,20086581 ! regulation of mitosis GO:0007088 112 63 0,000 0,19059862 0,20368872 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,19059862 0,20359966 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,19059862 0,20351067 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,19059862 0,20342176 ! hydrogen transport GO:0006818 121 64 0,000 0,19331327 0,20622896 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,19331327 0,20613895 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,19331327 0,20604901 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,1960189 0,20884177 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,1960189 0,20875073 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,1960189 0,20865977 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,1960189 0,20856889 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,1960189 0,20847809 ! ear development GO:0043583 114 66 0,000 0,19871553 0,21125415 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,19871553 0,21116226 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,19871553 0,21107045 ! gonad development GO:0008406 115 66 0,000 0,19871553 0,21097872 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,20140319 0,21373936 ! activation of MAPK activity GO:0000187 124 67 0,000 0,20140319 0,21364655 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,20140319 0,21355382 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,20140319 0,21346117 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,20140319 0,2133686 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,20140319 0,21327612 ! secondary metabolic process GO:0019748 125 67 0,000 0,20140319 0,21318371 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,20140319 0,21309138 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,20408192 0,21583209 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,20408192 0,21573869 ! hexose catabolic process GO:0019320 113 68 0,000 0,20408192 0,21564538 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,20408192 0,21555215 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,20408192 0,215459 ! viral reproduction GO:0016032 142 68 0,000 0,20408192 0,21536593 ! regulation of lipase activity GO:0060191 137 68 0,000 0,20408192 0,21527294 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,20408192 0,21518003 ! negative regulation of cell size GO:0045792 144 69 0,000 0,20675173 0,21790098 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,20675173 0,21780702 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,20675173 0,21771313 ! lung development GO:0030324 165 69 0,000 0,20675173 0,21761933 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,20675173 0,21752561 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,20675173 0,21743197 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,20675173 0,21733841 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,20675173 0,21724493 ! single fertilization GO:0007338 83 69 0,000 0,20675173 0,21715154 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,20941266 0,21985179 ! cell redox homeostasis GO:0045454 114 70 0,000 0,20941266 0,21975736 ! germ cell development GO:0007281 133 70 0,000 0,20941266 0,219663 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,21206474 0,22234942 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,21206474 0,22225404 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,21206474 0,22215873 ! appendage morphogenesis GO:0035107 150 72 0,000 0,214708 0,22483139 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,214708 0,22473506 ! respiratory tube development GO:0030323 171 72 0,000 0,214708 0,22463882 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,214708 0,22454265 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,214708 0,22444657 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,214708 0,22435057 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,214708 0,22425466 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,214708 0,22415882 ! appendage development GO:0048736 151 73 0,000 0,21734246 0,22681232 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,21734246 0,22671547 ! regulation of immune effector process GO:0002697 156 73 0,000 0,21734246 0,22661871 ! amino acid transport GO:0006865 148 74 0,000 0,21996816 0,22925863 ! regulation of caspase activity GO:0043281 136 74 0,000 0,21996816 0,22916086 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,21996816 0,22906318 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,21996816 0,22896558 ! respiratory system development GO:0060541 175 74 0,000 0,21996816 0,22886807 ! transition metal ion transport GO:0000041 143 75 0,000 0,22258513 0,23149233 ! reproductive structure development GO:0048608 131 75 0,000 0,22258513 0,23139382 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,22258513 0,23129539 ! eye development GO:0001654 155 75 0,000 0,22258513 0,23119705 ! rhythmic process GO:0048511 142 75 0,000 0,22258513 0,2310988 ! regulation of blood pressure GO:0008217 134 76 0,000 0,22519339 0,2337075 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,22519339 0,23360826 ! amine catabolic process GO:0009310 136 77 0,000 0,22779297 0,23620468 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,22779297 0,23610447 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,22779297 0,23600434 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,22779297 0,23590429 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,22779297 0,23580434 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,23038391 0,23838538 ! antigen processing and presentation GO:0019882 117 78 0,000 0,23038391 0,23828445 ! fertilization GO:0009566 99 78 0,000 0,23038391 0,23818361 ! blood coagulation GO:0007596 151 79 0,000 0,23296622 0,24075147 GO:0050817|coagulation, ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,23296622 0,24064967 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,23296622 0,24054796 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,23296622 0,24044633 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,23296622 0,24034479 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,23553994 0,24289746 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,23553994 0,24279497 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,23553994 0,24269257 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,23553994 0,24259025 ! muscle cell differentiation GO:0042692 178 81 0,000 0,2381051 0,24512885 ! response to hypoxia GO:0001666 178 81 0,000 0,2381051 0,24502559 ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,2381051 0,24492242 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,2381051 0,24481934 ! protein import into nucleus GO:0006606 174 82 0,000 0,24066172 0,24734396 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,24320983 0,24985771 ! exocytosis GO:0006887 153 83 0,000 0,24320983 0,24975268 ! response to drug GO:0042493 149 83 0,000 0,24320983 0,24964774 ! response to oxygen levels GO:0070482 183 83 0,000 0,24320983 0,24954289 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,24320983 0,24943813 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,24320983 0,24933346 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,24320983 0,24922887 ! nuclear import GO:0051170 177 83 0,000 0,24320983 0,24912437 ! inorganic anion transport GO:0015698 156 83 0,000 0,24320983 0,24901996 ! response to nutrient GO:0007584 135 84 0,000 0,24574947 0,25151485 ! digestion GO:0007586 130 84 0,000 0,24574947 0,25140953 ! regulation of ligase activity GO:0051340 147 84 0,000 0,24574947 0,25130429 ! hemostasis GO:0007599 165 85 0,000 0,24828066 0,25378646 ! negative regulation of transport GO:0051051 164 85 0,000 0,24828066 0,25368032 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,24828066 0,25357426 ! negative regulation of growth GO:0045926 168 85 0,000 0,24828066 0,2534683 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,24828066 0,25336242 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,24828066 0,25325664 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,24828066 0,25315094 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,25080342 0,2556165 ! regulation of lyase activity GO:0051339 169 86 0,000 0,25080342 0,2555099 ! mitochondrion organization GO:0007005 159 87 0,000 0,25331778 0,25796388 ! alcohol catabolic process GO:0046164 142 87 0,000 0,25331778 0,25785639 ! nucleosome assembly GO:0006334 126 87 0,000 0,25331778 0,257749 ! regulation of protein transport GO:0051223 165 87 0,000 0,25331778 0,25764169 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,25582378 0,26008219 ! amine biosynthetic process GO:0009309 146 88 0,000 0,25582378 0,259974 ! sensory perception of smell GO:0007608 117 88 0,000 0,25582378 0,2598659 ! chromatin assembly GO:0031497 128 88 0,000 0,25582378 0,2597579 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,25582378 0,25964998 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,25832144 0,26207611 ! tube morphogenesis GO:0035239 194 89 0,000 0,25832144 0,26196732 ! protein localization in nucleus GO:0034504 192 89 0,000 0,25832144 0,26185862 ! regulation of neurological system process GO:0031644 175 89 0,000 0,25832144 0,26175001 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,26081079 0,26416283 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,26081079 0,26405336 ! response to unfolded protein GO:0006986 139 90 0,000 0,26081079 0,26394397 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,26081079 0,26383468 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,26329185 0,26623426 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,26329185 0,26612411 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,26576465 0,26851242 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,26576465 0,26840142 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,26822922 0,27077851 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,26822922 0,27066666 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,26822922 0,27055491 ! vitamin metabolic process GO:0006766 153 93 0,000 0,26822922 0,27044325 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,27068559 0,2728073 ! female pregnancy GO:0007565 166 94 0,000 0,27068559 0,2726948 ! sterol metabolic process GO:0016125 166 94 0,000 0,27068559 0,2725824 ! regulation of membrane potential GO:0042391 179 94 0,000 0,27068559 0,27247008 ! regulation of defense response GO:0031347 171 95 0,000 0,27313378 0,27482118 ! nucleosome organization GO:0034728 143 95 0,000 0,27313378 0,27470804 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,27313378 0,27459499 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,27313378 0,27448204 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,27313378 0,27436917 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,27313378 0,2742564 ! sex differentiation GO:0007548 171 96 0,000 0,27557382 0,27659279 ! response to protein stimulus GO:0051789 158 96 0,000 0,27557382 0,2764792 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,27800574 0,27880461 ! transcription initiation GO:0006352 171 97 0,000 0,27800574 0,27869021 ! regulation of protein localization GO:0032880 188 97 0,000 0,27800574 0,2785759 ! leukocyte differentiation GO:0002521 232 98 0,000 0,28042957 0,28088948 ! interphase of mitotic cell cycle GO:0051329 224 98 0,000 0,28042957 0,28077436 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,28042957 0,28065934 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,28525304 0,28536985 GO:0060538|skeletal muscle organ development, ! hormone metabolic process GO:0042445 171 100 0,000 0,28525304 0,28525304