pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/999-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 4,000 5,704E-08 1,372E-04 ! positive regulation of cell migration GO:0030335 126 57 5,000 6,81E-08 8,192E-05 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 4,000 1,155E-07 9,264E-05 ! positive regulation of cell motion GO:0051272 146 64 5,000 1,378E-07 8,287E-05 ! catecholamine biosynthetic process GO:0042423 30 14 3,000 1,7E-07 8,181E-05 ! mRNA catabolic process GO:0006402 71 39 4,000 3,235E-07 1,297E-04 ! RNA catabolic process GO:0006401 93 53 4,000 1,548E-06 5,32E-04 ! heart morphogenesis GO:0003007 97 55 4,000 1,865E-06 5,61E-04 ! catechol metabolic process GO:0009712 54 29 3,000 3,866E-06 1,033E-03 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! phenol metabolic process GO:0018958 55 30 3,000 4,448E-06 1,07E-03 ! positive regulation of heart contraction GO:0045823 16 10 2,000 5,738E-06 1,255E-03 ! biogenic amine biosynthetic process GO:0042401 62 34 3,000 7,441E-06 1,492E-03 ! negative regulation of hydrolase activity GO:0051346 62 35 3,000 8,378E-06 1,551E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 1,722E-05 2,959E-03 ! cardiac muscle contraction GO:0060048 26 15 2,000 2,147E-05 3,443E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 2,000 2,147E-05 3,228E-03 ! regulation of ATPase activity GO:0043462 21 15 2,000 2,147E-05 3,038E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 2,635E-05 3,522E-03 ! mRNA transport GO:0051028 169 96 4,000 2,907E-05 3,681E-03 ! regulation of DNA metabolic process GO:0051052 178 97 4,000 3,056E-05 3,676E-03 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 2,000 3,191E-05 3,656E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 3,191E-05 3,49E-03 ! regulation of muscle contraction GO:0006937 81 52 3,000 4,128E-05 4,318E-03 ! heart process GO:0003015 30 19 2,000 4,523E-05 4,534E-03 GO:0060047|heart contraction, ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 3,000 4,795E-05 4,614E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 5,306E-05 4,91E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 5,537E-05 4,934E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 6,174E-05 5,305E-03 ! cellular response to reactive oxygen species GO:0034614 31 22 2,000 7,13E-05 5,915E-03 ! apoptotic nuclear changes GO:0030262 32 22 2,000 7,13E-05 5,718E-03 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 2,000 7,13E-05 5,534E-03 GO:0060415|muscle tissue morphogenesis, ! positive regulation of cell adhesion GO:0045785 56 23 2,000 8,177E-05 6,148E-03 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 2,000 8,177E-05 5,962E-03 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 9,32E-05 6,596E-03 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 9,32E-05 6,407E-03 ! vasculogenesis GO:0001570 46 25 2,000 1,056E-04 7,06E-03 ! regulation of smooth muscle contraction GO:0006940 43 25 2,000 1,056E-04 6,869E-03 ! cellular response to oxidative stress GO:0034599 39 26 2,000 1,191E-04 7,54E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 1,336E-04 8,243E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,336E-04 8,039E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 1,336E-04 7,843E-03 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 1,336E-04 7,656E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 1,336E-04 7,478E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 1,336E-04 7,308E-03 ! muscle cell proliferation GO:0033002 11 5 1,000 1,336E-04 7,146E-03 ! regulation of hair follicle development GO:0051797 10 5 1,000 1,336E-04 6,99E-03 GO:0042634|regulation of hair cycle, ! glial cell migration GO:0008347 11 5 1,000 1,336E-04 6,842E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 1,336E-04 6,699E-03 ! positive regulation of actin filament bundle formation GO:0032233 17 5 1,000 1,336E-04 6,562E-03 ! stem cell division GO:0017145 11 5 1,000 1,336E-04 6,431E-03 GO:0048103|somatic stem cell division, ! regulation of caspase activity GO:0043281 122 72 3,000 1,482E-04 6,993E-03 ! regulation of systemic arterial blood pressure GO:0003073 54 28 2,000 1,492E-04 6,906E-03 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 1,648E-04 7,483E-03 ! regulation of smooth muscle cell differentiation GO:0051150 9 6 1,000 2E-04 8,911E-03 ! response to exogenous dsRNA GO:0043330 10 6 1,000 2E-04 8,749E-03 ! salivary gland morphogenesis GO:0007435 13 6 1,000 2E-04 8,592E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 2E-04 8,442E-03 ! regulation of peptidase activity GO:0052547 134 79 3,000 2,122E-04 8,804E-03 ! response to hypoxia GO:0001666 171 81 3,000 2,337E-04 9,53E-03 ! cell-substrate adhesion GO:0031589 171 81 3,000 2,337E-04 9,371E-03 ! response to drug GO:0042493 143 82 3,000 2,45E-04 9,663E-03 ! DNA damage checkpoint GO:0000077 71 33 2,000 2,453E-04 9,517E-03 ! positive regulation of gene-specific transcription GO:0043193 65 33 2,000 2,453E-04 9,366E-03 ! response to oxygen levels GO:0070482 176 83 3,000 2,567E-04 9,649E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 2,793E-04 0,01033868 ! prostate gland development GO:0030850 13 7 1,000 2,793E-04 0,01018203 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 2,793E-04 0,01003006 ! actin-myosin filament sliding GO:0033275 11 7 1,000 2,793E-04 9,883E-03 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! mRNA stabilization GO:0048255 18 7 1,000 2,793E-04 9,739E-03 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 2,793E-04 9,6E-03 ! positive regulation of heart rate GO:0010460 10 7 1,000 2,793E-04 9,465E-03 ! macrophage differentiation GO:0030225 11 7 1,000 2,793E-04 9,334E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 2,793E-04 9,206E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 2,793E-04 9,081E-03 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 1,000 2,793E-04 8,96E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 2,793E-04 8,842E-03 ! response to tumor cell GO:0002347 13 7 1,000 2,793E-04 8,727E-03 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 1,000 2,793E-04 8,616E-03 ! dopamine biosynthetic process GO:0042416 18 7 1,000 2,793E-04 8,507E-03 ! positive regulation of ATPase activity GO:0032781 11 7 1,000 2,793E-04 8,4E-03 ! positive regulation of smooth muscle contraction GO:0045987 10 7 1,000 2,793E-04 8,296E-03 ! amine biosynthetic process GO:0009309 138 86 3,000 2,941E-04 8,629E-03 ! DNA integrity checkpoint GO:0031570 75 36 2,000 3,184E-04 9,229E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 3,715E-04 0,01064119 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 3,715E-04 0,010516 ! T-helper 1 type immune response GO:0042088 12 8 1,000 3,715E-04 0,01039372 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 1,000 3,715E-04 0,01027425 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 3,715E-04 0,0101575 ! ER overload response GO:0006983 12 8 1,000 3,715E-04 0,01004337 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 3,715E-04 9,932E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 3,715E-04 9,823E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 3,715E-04 9,716E-03 ! positive regulation of epidermis development GO:0045684 13 8 1,000 3,715E-04 9,611E-03 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 3,715E-04 9,509E-03 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 1,000 3,715E-04 9,409E-03 ! B cell receptor signaling pathway GO:0050853 16 8 1,000 3,715E-04 9,311E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 3,715E-04 9,215E-03 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 3,742E-04 9,186E-03 ! nucleus organization GO:0006997 67 38 2,000 3,742E-04 9,093E-03 ! biogenic amine metabolic process GO:0006576 155 94 3,000 4,129E-04 9,934E-03 ! induction of positive chemotaxis GO:0050930 15 9 1,000 4,765E-04 0,01135129 ! microtubule bundle formation GO:0001578 21 9 1,000 4,765E-04 0,01124 ! middle ear morphogenesis GO:0042474 14 9 1,000 4,765E-04 0,01113087 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 4,765E-04 0,01102385 ! ruffle organization GO:0031529 15 9 1,000 4,765E-04 0,01091886 ! motor axon guidance GO:0008045 16 9 1,000 4,765E-04 0,01081585 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 1,000 4,765E-04 0,01071477 ! regulation of telomere maintenance GO:0032204 14 9 1,000 4,765E-04 0,01061556 ! pyrimidine base metabolic process GO:0006206 17 9 1,000 4,765E-04 0,01051816 ! response to reactive oxygen species GO:0000302 67 42 2,000 5,037E-04 0,01101819 ! cell cycle arrest GO:0007050 213 100 3,000 5,22E-04 0,01131477 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 5,401E-04 0,01160194 ! striated muscle contraction GO:0006941 77 43 2,000 5,401E-04 0,01149927 ! regulation of phosphatase activity GO:0010921 28 10 1,000 5,942E-04 0,01254078 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 5,942E-04 0,01243173 ! lung alveolus development GO:0048286 26 10 1,000 5,942E-04 0,01232456 ! regulation of stress fiber formation GO:0051492 30 10 1,000 5,942E-04 0,01221922 ! positive regulation of muscle contraction GO:0045933 14 10 1,000 5,942E-04 0,01211567 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 5,942E-04 0,01201385 ! regulation of bone resorption GO:0045124 25 10 1,000 5,942E-04 0,01191374 ! response to dsRNA GO:0043331 20 10 1,000 5,942E-04 0,01181528 ! DNA ligation GO:0006266 19 10 1,000 5,942E-04 0,01171843 ! salivary gland development GO:0007431 27 10 1,000 5,942E-04 0,01162316 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 5,942E-04 0,01152942 ! blastocyst formation GO:0001825 17 10 1,000 5,942E-04 0,01143719 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 5,942E-04 0,01134642 ! localization within membrane GO:0051668 20 10 1,000 5,942E-04 0,01125708 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 6,177E-04 0,01161037 ! cell growth GO:0016049 84 45 2,000 6,177E-04 0,01152037 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 6,59E-04 0,01219663 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 7,245E-04 0,01330642 ! detection of mechanical stimulus GO:0050982 22 11 1,000 7,245E-04 0,01320562 ! blood vessel remodeling GO:0001974 29 11 1,000 7,245E-04 0,01310633 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 7,245E-04 0,01300852 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 7,245E-04 0,01291216 ! regulation of intracellular pH GO:0051453 19 11 1,000 7,245E-04 0,01281722 ! DNA methylation GO:0006306 19 11 1,000 7,245E-04 0,01272366 GO:0006305|DNA alkylation, ! regulation of leukocyte migration GO:0002685 26 11 1,000 7,245E-04 0,01263146 ! regulation of actin filament bundle formation GO:0032231 33 11 1,000 7,245E-04 0,01254059 ! T cell receptor signaling pathway GO:0050852 23 11 1,000 7,245E-04 0,01245101 ! positive regulation of cell cycle GO:0045787 89 48 2,000 7,469E-04 0,01274426 ! cellular component disassembly GO:0022411 86 48 2,000 7,469E-04 0,01265451 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 2,000 7,469E-04 0,01256602 ! activation of caspase activity GO:0006919 84 48 2,000 7,469E-04 0,01247875 ! positive regulation of blood pressure GO:0045777 17 12 1,000 8,673E-04 0,01439128 ! cartilage condensation GO:0001502 20 12 1,000 8,673E-04 0,01429271 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 8,673E-04 0,01419548 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 8,673E-04 0,01409956 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 8,673E-04 0,01400493 ! positive regulation of cell growth GO:0030307 22 12 1,000 8,673E-04 0,01391157 ! focal adhesion formation GO:0048041 35 12 1,000 8,673E-04 0,01381944 ! histone acetylation GO:0016573 26 12 1,000 8,673E-04 0,01372852 ! gland morphogenesis GO:0022612 29 12 1,000 8,673E-04 0,01363879 ! peptidyl-lysine modification GO:0018205 21 12 1,000 8,673E-04 0,01355023 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 8,673E-04 0,01346281 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 9,981E-04 0,01539416 ! response to UV GO:0009411 104 53 2,000 9,981E-04 0,0152961 ! response to X-ray GO:0010165 25 13 1,000 1,023E-03 0,01557093 ! exocrine system development GO:0035272 32 13 1,000 1,023E-03 0,015473 ! regulation of cellular pH GO:0030641 22 13 1,000 1,023E-03 0,01537629 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,023E-03 0,01528079 ! regulation of epidermis development GO:0045682 19 13 1,000 1,023E-03 0,01518646 ! regulation of mRNA stability GO:0043488 31 13 1,000 1,023E-03 0,0150933 ! positive regulation of caspase activity GO:0043280 95 55 2,000 1,112E-03 0,01631168 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 2,000 1,112E-03 0,01621282 ! nuclear export GO:0051168 97 55 2,000 1,112E-03 0,01611515 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,19E-03 0,01714573 ! hair follicle morphogenesis GO:0031069 26 14 1,000 1,19E-03 0,01704367 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 1,19E-03 0,01694282 ! regulation of heart rate GO:0002027 24 14 1,000 1,19E-03 0,01684316 ! response to gamma radiation GO:0010332 28 14 1,000 1,19E-03 0,01674466 ! regulation of RNA stability GO:0043487 32 14 1,000 1,19E-03 0,01664731 ! regulation of bone remodeling GO:0046850 137 57 2,000 1,233E-03 0,01715416 ! regulation of tissue remodeling GO:0034103 140 58 2,000 1,297E-03 0,01793791 ! skeletal system morphogenesis GO:0048705 105 59 2,000 1,363E-03 0,01874076 ! DNA catabolic process GO:0006308 86 59 2,000 1,363E-03 0,01863428 ! positive regulation of cell size GO:0045793 27 15 1,000 1,37E-03 0,01862093 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 1,37E-03 0,01851632 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,37E-03 0,01841288 ! muscle maintenance GO:0046716 26 15 1,000 1,37E-03 0,01831058 ! dopamine metabolic process GO:0042417 35 15 1,000 1,37E-03 0,01820942 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 1,37E-03 0,01810937 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 1,000 1,37E-03 0,01801041 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 1,431E-03 0,01871218 ! regulation of heart contraction GO:0008016 110 60 2,000 1,431E-03 0,01861104 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 1,562E-03 0,02020265 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 1,562E-03 0,02009461 GO:0031114|regulation of microtubule depolymerization, ! regulation of dephosphorylation GO:0035303 43 16 1,000 1,562E-03 0,01998773 ! negative regulation of immune response GO:0050777 35 16 1,000 1,562E-03 0,01988197 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 1,562E-03 0,01977733 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 1,562E-03 0,01967378 ! regulation of homeostatic process GO:0032844 134 62 2,000 1,573E-03 0,01971352 ! endothelial cell migration GO:0043542 28 17 1,000 1,766E-03 0,02201286 ! regulation of muscle cell differentiation GO:0051147 33 17 1,000 1,766E-03 0,02189939 ! heart looping GO:0001947 30 17 1,000 1,766E-03 0,02178709 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 1,766E-03 0,02167593 ! regulation of survival gene product expression GO:0045884 33 17 1,000 1,766E-03 0,0215659 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 1,766E-03 0,02145698 ! nucleobase metabolic process GO:0009112 37 17 1,000 1,766E-03 0,02134916 ! neutrophil chemotaxis GO:0030593 27 17 1,000 1,766E-03 0,02124241 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 1,766E-03 0,02113673 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 1,766E-03 0,02103209 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 1,766E-03 0,02092848 ! extracellular matrix organization GO:0030198 133 66 2,000 1,883E-03 0,02221086 ! regulation of cellular response to stress GO:0080135 128 67 2,000 1,966E-03 0,02307695 ! negative regulation of cell growth GO:0030308 132 67 2,000 1,966E-03 0,02296493 ! lung development GO:0030324 144 67 2,000 1,966E-03 0,02285399 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,982E-03 0,02292335 ! epidermis morphogenesis GO:0048730 40 18 1,000 1,982E-03 0,02281367 ! cell-substrate junction assembly GO:0007044 54 18 1,000 1,982E-03 0,02270504 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 1,982E-03 0,02259743 ! cell cycle checkpoint GO:0000075 137 69 2,000 2,139E-03 0,02427624 ! negative regulation of cell size GO:0045792 134 69 2,000 2,139E-03 0,02416227 ! lipid phosphorylation GO:0046834 35 19 1,000 2,21E-03 0,02484208 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 2,21E-03 0,02472653 ! response to lipopolysaccharide GO:0032496 30 19 1,000 2,21E-03 0,02461206 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 2,21E-03 0,02449864 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 2,21E-03 0,02438626 ! G1 phase GO:0051318 40 19 1,000 2,21E-03 0,0242749 ! respiratory tube development GO:0030323 150 70 2,000 2,229E-03 0,02437588 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 2,321E-03 0,0252687 ! respiratory system development GO:0060541 153 72 2,000 2,415E-03 0,02617872 ! positive regulation of ossification GO:0045778 47 20 1,000 2,449E-03 0,0264247 ! protein amino acid acetylation GO:0006473 39 20 1,000 2,449E-03 0,02630673 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 2,449E-03 0,02618981 ! response to alkaloid GO:0043279 38 20 1,000 2,449E-03 0,02607393 ! cellular response to starvation GO:0009267 33 20 1,000 2,449E-03 0,02595907 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 2,449E-03 0,02584521 ! actin filament-based movement GO:0030048 43 20 1,000 2,449E-03 0,02573235 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 2,449E-03 0,02562047 ! regulation of blood pressure GO:0008217 125 73 2,000 2,512E-03 0,0261672 ! cell aging GO:0007569 44 21 1,000 2,7E-03 0,02800585 ! DNA modification GO:0006304 34 21 1,000 2,7E-03 0,02788565 ! positive regulation of locomotion GO:0040017 39 21 1,000 2,7E-03 0,02776648 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 1,000 2,7E-03 0,02764832 ! response to cytokine stimulus GO:0034097 63 21 1,000 2,7E-03 0,02753117 ! collagen catabolic process GO:0030574 28 21 1,000 2,7E-03 0,02741501 ! cell-matrix adhesion GO:0007160 163 75 2,000 2,713E-03 0,02742717 ! positive regulation of bone remodeling GO:0046852 51 22 1,000 2,963E-03 0,02983237 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 40 22 1,000 2,963E-03 0,02970807 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 2,963E-03 0,0295848 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 2,963E-03 0,02946255 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 2,963E-03 0,02934131 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 2,963E-03 0,02922106 ! sarcomere organization GO:0045214 30 22 1,000 2,963E-03 0,02910179 ! activation of JUN kinase activity GO:0007257 42 22 1,000 2,963E-03 0,02898349 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 2,963E-03 0,02886614 ! protein oligomerization GO:0051259 139 78 2,000 3,032E-03 0,02941851 ! positive regulation of DNA replication GO:0045740 43 23 1,000 3,238E-03 0,03128611 ! myeloid leukocyte differentiation GO:0002573 40 23 1,000 3,238E-03 0,03116097 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 1,000 3,238E-03 0,03103682 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 3,238E-03 0,03091366 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 1,000 3,238E-03 0,03079147 ! platelet activation GO:0030168 37 23 1,000 3,238E-03 0,03067024 ! response to molecule of bacterial origin GO:0002237 34 23 1,000 3,238E-03 0,03054997 ! protein import into nucleus GO:0006606 158 80 2,000 3,257E-03 0,03061495 ! nuclear import GO:0051170 161 81 2,000 3,374E-03 0,0315846 ! regulation of behavior GO:0050795 43 24 1,000 3,524E-03 0,03286069 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 3,524E-03 0,03273382 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 3,524E-03 0,03260792 ! protein tetramerization GO:0051262 52 24 1,000 3,524E-03 0,03248299 ! negative regulation of growth GO:0045926 155 84 2,000 3,738E-03 0,03432505 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 3,821E-03 0,03495507 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 3,821E-03 0,03482266 ! negative regulation of DNA replication GO:0008156 42 25 1,000 3,821E-03 0,03469125 ! response to starvation GO:0042594 42 25 1,000 3,821E-03 0,03456083 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 3,821E-03 0,03443139 ! negative regulation of cell development GO:0010721 73 25 1,000 3,821E-03 0,03430292 GO:0050768|negative regulation of neurogenesis, ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 3,821E-03 0,0341754 ! somitogenesis GO:0001756 43 25 1,000 3,821E-03 0,03404882 ! cellular response to nutrient levels GO:0031669 41 25 1,000 3,821E-03 0,03392318 ! liver development GO:0001889 53 25 1,000 3,821E-03 0,03379846 ! mitochondrion organization GO:0007005 148 86 2,000 3,993E-03 0,03519379 ! protein localization in nucleus GO:0034504 176 87 2,000 4,125E-03 0,03622128 ! molting cycle process GO:0022404 50 26 1,000 4,129E-03 0,03612874 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 4,129E-03 0,03599784 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 4,129E-03 0,03586788 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 4,129E-03 0,03573886 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 4,129E-03 0,03561077 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 4,129E-03 0,03548358 ! blastocyst development GO:0001824 49 26 1,000 4,129E-03 0,03535731 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 4,129E-03 0,03523193 ! gland development GO:0048732 206 88 2,000 4,259E-03 0,03621075 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 4,396E-03 0,03724288 ! regulation of cell adhesion GO:0030155 212 89 2,000 4,396E-03 0,0371122 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 4,449E-03 0,03742838 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 4,449E-03 0,03729797 ! protein amino acid acylation GO:0043543 55 27 1,000 4,449E-03 0,03716846 ! mitochondrial membrane organization GO:0007006 57 27 1,000 4,449E-03 0,03703985 ! multicellular organismal catabolic process GO:0044243 36 27 1,000 4,449E-03 0,03691213 ! response to toxin GO:0009636 47 27 1,000 4,449E-03 0,03678528 ! base-excision repair GO:0006284 41 27 1,000 4,449E-03 0,03665931 ! regulation of chromosome organization GO:0033044 42 27 1,000 4,449E-03 0,03653419 ! ossification GO:0001503 188 90 2,000 4,536E-03 0,03711793 ! bone development GO:0060348 189 91 2,000 4,678E-03 0,03815173 ! dendrite development GO:0016358 59 28 1,000 4,78E-03 0,03885243 ! negative regulation of protein modification process GO:0031400 60 28 1,000 4,78E-03 0,03872162 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 4,78E-03 0,03859168 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 4,78E-03 0,03846261 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 4,97E-03 0,03986087 ! regulation of pH GO:0006885 43 29 1,000 5,122E-03 0,04093889 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 5,122E-03 0,04080333 ! immune response-activating signal transduction GO:0002757 47 29 1,000 5,122E-03 0,04066867 GO:0002764|immune response-regulating signal transduction, ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 5,122E-03 0,04053489 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 5,122E-03 0,04040199 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 5,273E-03 0,04146323 ! leukocyte differentiation GO:0002521 202 96 2,000 5,429E-03 0,04254827 ! positive regulation of immune response GO:0050778 156 96 2,000 5,429E-03 0,04241013 ! cell junction assembly GO:0034329 78 30 1,000 5,474E-03 0,04262516 ! myofibril assembly GO:0030239 47 30 1,000 5,474E-03 0,04248766 GO:0055002|striated muscle cell development, ! interphase GO:0051325 213 98 2,000 5,749E-03 0,04447354 ! mRNA export from nucleus GO:0006406 48 31 1,000 5,838E-03 0,04501867 ! collagen metabolic process GO:0032963 45 31 1,000 5,838E-03 0,04487484 ! iron ion homeostasis GO:0055072 54 31 1,000 5,838E-03 0,04473193 ! response to ionizing radiation GO:0010212 65 32 1,000 6,212E-03 0,04744875 ! response to mechanical stimulus GO:0009612 57 32 1,000 6,212E-03 0,04729859 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 6,212E-03 0,04714939 ! muscle cell development GO:0055001 49 32 1,000 6,212E-03 0,04700112 ! leukocyte chemotaxis GO:0030595 50 33 1,000 6,597E-03 0,04975726 GO:0060326|cell chemotaxis, ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 6,993E-03 0,05257582 ! placenta development GO:0001890 53 34 1,000 6,993E-03 0,05241203 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 7,399E-03 0,05528337 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 7,399E-03 0,05511221 ! calcium-mediated signaling GO:0019722 62 35 1,000 7,399E-03 0,05494211 ! regulation of microtubule-based process GO:0032886 78 35 1,000 7,399E-03 0,05477306 ! cell junction organization GO:0034330 86 36 1,000 7,815E-03 0,05767888 ! positive regulation of cell development GO:0010720 80 36 1,000 7,815E-03 0,0575025 ! RNA export from nucleus GO:0006405 56 37 1,000 8,242E-03 0,06045818 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 8,242E-03 0,06027442 ! actomyosin structure organization GO:0031032 62 37 1,000 8,242E-03 0,06009177 ! tissue remodeling GO:0048771 76 37 1,000 8,242E-03 0,05991022 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 8,242E-03 0,05972977 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 8,242E-03 0,0595504 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 8,679E-03 0,06252082 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 8,679E-03 0,06233419 ! ear morphogenesis GO:0042471 60 39 1,000 9,126E-03 0,06535159 ! segmentation GO:0035282 67 39 1,000 9,126E-03 0,06515767 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 9,584E-03 0,0682208 ! mesenchymal cell development GO:0014031 87 40 1,000 9,584E-03 0,06801956 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! gliogenesis GO:0042063 88 41 1,000 0,01005123 0,07112722 ! T cell differentiation GO:0030217 81 41 1,000 0,01005123 0,07091864 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,0105286 0,07406965 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,0105286 0,0738537 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,0105286 0,07363901 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,0105286 0,07342556 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,01101585 0,07660154 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,01101585 0,07638078 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,01101585 0,0761613 ! double-strand break repair GO:0006302 81 44 1,000 0,01151289 0,07936964 ! biopolymer methylation GO:0043414 84 44 1,000 0,01151289 0,07914287 ! B cell differentiation GO:0030183 107 44 1,000 0,01151289 0,0789174 ! leukocyte migration GO:0050900 68 45 1,000 0,01201964 0,08215698 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,01201964 0,08192424 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 0,01253603 0,08520253 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,01253603 0,08496253 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,01253603 0,08472387 ! pigmentation GO:0043473 100 46 1,000 0,01253603 0,08448655 ! response to insulin stimulus GO:0032868 95 46 1,000 0,01253603 0,08425055 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,01253603 0,08401587 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01306199 0,08729762 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,01306199 0,0870558 ! JNK cascade GO:0007254 91 47 1,000 0,01306199 0,08681531 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,01306199 0,08657615 ! methylation GO:0032259 90 47 1,000 0,01306199 0,08633831 ! protein homooligomerization GO:0051260 76 47 1,000 0,01306199 0,08610176 ! mitochondrial transport GO:0006839 82 48 1,000 0,01359743 0,08938637 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,01414228 0,09271478 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,01414228 0,09246284 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,01414228 0,09221226 ! regulation of ossification GO:0030278 117 50 1,000 0,01469646 0,09556674 ! histone modification GO:0016570 91 50 1,000 0,01469646 0,09530915 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,01469646 0,09505294 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,01469646 0,09479811 ! positive regulation of binding GO:0051099 78 51 1,000 0,01525991 0,09816936 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,01525991 0,09790758 ! regulation of cell shape GO:0008360 125 51 1,000 0,01525991 0,09764719 ! positive regulation of growth GO:0045927 90 52 1,000 0,01583254 0,10104268 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01583254 0,10077537 ! cartilage development GO:0051216 90 52 1,000 0,01583254 0,10050948 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01700506 0,10766889 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,01700506 0,10738629 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,0176048 0,11088262 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,0176048 0,11059311 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,01821344 0,11411859 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,01821344 0,11382217 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,018294 0,11402943 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,018294 0,11373478 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,018294 0,11344164 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,018294 0,11315002 ! neuron fate determination GO:0048664 7 5 0,000 0,018294 0,11285989 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,018294 0,11257125 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,018294 0,11228408 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,018294 0,11199837 ! polyol transport GO:0015791 12 5 0,000 0,018294 0,11171411 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,018294 0,11143129 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,018294 0,11114989 ! response to superoxide GO:0000303 10 5 0,000 0,018294 0,11086992 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,018294 0,11059135 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,018294 0,11031418 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,018294 0,1100384 ! female meiosis GO:0007143 7 5 0,000 0,018294 0,10976399 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,018294 0,10949094 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,018294 0,10921925 ! cobalt ion transport GO:0006824 11 5 0,000 0,018294 0,10894891 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,018294 0,1086799 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,018294 0,10841221 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,018294 0,10814584 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,018294 0,10788078 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,018294 0,10761701 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,018294 0,10735453 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,018294 0,10709333 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,018294 0,10683339 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,018294 0,10657472 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,018294 0,10631729 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,018294 0,1060611 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,018294 0,10580615 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,018294 0,10555242 ! negative chemotaxis GO:0050919 14 5 0,000 0,018294 0,1052999 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,018294 0,10504859 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,018294 0,10479847 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,018294 0,10454954 ! behavioral response to pain GO:0048266 9 5 0,000 0,018294 0,1043018 ! clathrin coat assembly GO:0048268 14 5 0,000 0,018294 0,10405522 ! Notch receptor processing GO:0007220 8 5 0,000 0,018294 0,10380981 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,018294 0,10356555 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,018294 0,10332244 ! micturition GO:0060073 9 5 0,000 0,018294 0,10308046 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,018294 0,10283962 ! copulation GO:0007620 9 5 0,000 0,018294 0,1025999 ! glial cell fate commitment GO:0021781 13 5 0,000 0,018294 0,1023613 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,018294 0,1021238 ! spermidine metabolic process GO:0008216 7 5 0,000 0,018294 0,1018874 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,018294 0,1016521 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,018294 0,10141788 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,018294 0,10118473 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,018294 0,10095266 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,018294 0,10072164 ! grooming behavior GO:0007625 6 5 0,000 0,018294 0,10049169 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,018294 0,10026277 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,018294 0,1000349 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,018294 0,09980807 ! response to protozoan GO:0001562 10 5 0,000 0,018294 0,09958226 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,018294 0,09935747 ! lymph vessel development GO:0001945 10 5 0,000 0,018294 0,09913369 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,018294 0,09891092 ! endochondral ossification GO:0001958 16 5 0,000 0,018294 0,09868914 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,018294 0,09846836 ! parathyroid gland development GO:0060017 13 5 0,000 0,018294 0,09824857 ! anagen GO:0042640 6 5 0,000 0,018294 0,09802975 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,018294 0,09781191 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,018294 0,09759503 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,018294 0,09737911 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,018294 0,09716415 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,018294 0,09695013 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,018294 0,09673705 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,018294 0,09652491 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,018294 0,09631369 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,018294 0,0961034 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,018294 0,09589403 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,018294 0,09568556 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,018294 0,095478 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,018294 0,09527134 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,018294 0,09506557 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,018294 0,09486069 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,018294 0,09465668 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,018294 0,09445356 ! histidine catabolic process GO:0006548 6 5 0,000 0,018294 0,0942513 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,018294 0,09404991 ! microvillus organization GO:0032528 7 5 0,000 0,018294 0,09384938 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,018294 0,0936497 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,018294 0,09345087 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,018294 0,09325288 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,018294 0,09305573 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,018294 0,09285941 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,018294 0,09266391 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,018294 0,09246924 ! polyol catabolic process GO:0046174 7 5 0,000 0,018294 0,09227538 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,018294 0,09208234 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,018294 0,0918901 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,018294 0,09169866 ! muscle cell migration GO:0014812 8 5 0,000 0,018294 0,09150802 ! mitochondrial fission GO:0000266 8 5 0,000 0,018294 0,09131817 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,018294 0,09112911 ! mRNA transcription GO:0009299 9 5 0,000 0,018294 0,09094082 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,018294 0,09075332 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,018294 0,09056658 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,018294 0,09038061 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,018294 0,09019541 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,018294 0,09001096 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,018294 0,08982726 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,018294 0,08964431 ! response to food GO:0032094 6 5 0,000 0,018294 0,08946211 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,018294 0,08928065 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,018294 0,08909992 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,018294 0,08891992 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,018294 0,08874064 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,018294 0,08856209 ! forebrain neuron development GO:0021884 13 5 0,000 0,018294 0,08838425 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,018294 0,08820713 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,018294 0,08803072 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,018294 0,08785501 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,018294 0,08768 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,018294 0,08750568 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,018294 0,08733206 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,018294 0,08715913 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,018294 0,08698687 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,018294 0,0868153 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,018294 0,08664441 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,018294 0,08647418 ! basic amino acid transport GO:0015802 11 5 0,000 0,018294 0,08630462 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,018294 0,08613573 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,018294 0,0859675 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,018294 0,08579992 ! depyrimidination GO:0045008 10 5 0,000 0,018294 0,08563299 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,018294 0,08546671 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,018294 0,08530108 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,018294 0,08513609 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,018294 0,08497173 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,018294 0,08480801 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,018294 0,08464492 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,018294 0,08448245 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,018294 0,08432061 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,018294 0,08415938 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,018294 0,08399878 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,018294 0,08383878 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,018294 0,08367939 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,018294 0,0835206 ! response to arsenic GO:0046685 10 5 0,000 0,018294 0,08336242 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,018294 0,08320484 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,018294 0,08304785 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,018294 0,08289145 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,018294 0,08273564 ! response to cadmium ion GO:0046686 7 5 0,000 0,018294 0,08258041 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,018294 0,08242576 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,018294 0,0822717 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,018294 0,08211821 ! decidualization GO:0046697 11 5 0,000 0,018294 0,08196529 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,018294 0,08181293 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,018294 0,08166115 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,018294 0,08150992 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,018294 0,08135926 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,018294 0,08120915 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,018294 0,08105959 ! neural tube patterning GO:0021532 7 5 0,000 0,018294 0,08091058 ! embryonic cleavage GO:0040016 6 5 0,000 0,018294 0,08076213 ! peroxisome fission GO:0016559 5 5 0,000 0,018294 0,08061421 ! histone demethylation GO:0016577 10 5 0,000 0,018294 0,08046683 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,018294 0,08032 ! mitotic recombination GO:0006312 9 5 0,000 0,018294 0,08017369 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,018294 0,08002792 ! metaphase plate congression GO:0051310 7 5 0,000 0,018294 0,07988268 ! regulation of sterol transport GO:0032371 7 5 0,000 0,018294 0,07973797 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,018294 0,07959378 ! enteric nervous system development GO:0048484 8 5 0,000 0,018294 0,0794501 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,018294 0,07930695 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,018294 0,07916431 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,018294 0,07902219 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,018294 0,07888057 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,018294 0,07873946 ! plasminogen activation GO:0031639 5 5 0,000 0,018294 0,07859885 ! B cell homeostasis GO:0001782 13 5 0,000 0,018294 0,07845875 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,018294 0,07831914 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,018294 0,07818003 ! metaphase GO:0051323 8 5 0,000 0,018294 0,07804142 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,018294 0,07790329 ! cellular response to nutrient GO:0031670 8 5 0,000 0,018294 0,07776565 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,018294 0,0776285 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,018294 0,07749183 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,018294 0,07735564 GO:0015991|ATP hydrolysis coupled proton transport, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,018294 0,07721993 ! response to redox state GO:0051775 5 5 0,000 0,018294 0,07708469 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,018294 0,07694993 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,018294 0,07681563 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,018294 0,07668181 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,018294 0,07654845 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,018294 0,07641555 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,018294 0,07628312 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,018294 0,07615114 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,018294 0,07601962 ! striatum development GO:0021756 9 5 0,000 0,018294 0,07588855 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,018294 0,07575793 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,018294 0,07562776 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,018294 0,07549804 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,018294 0,07536876 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,018294 0,07523993 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,018294 0,07511153 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,018294 0,07498357 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,018294 0,07485605 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,018294 0,07472896 ! neuroprotection GO:0043526 6 5 0,000 0,018294 0,0746023 ! neural plate development GO:0001840 8 5 0,000 0,018294 0,07447607 ! regulation of sensory perception GO:0051931 7 5 0,000 0,018294 0,07435027 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,018294 0,07422489 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,018294 0,07409993 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,018294 0,07397539 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,018294 0,07385127 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,018294 0,07372757 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,018294 0,07360428 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,018294 0,0734814 ! spindle assembly GO:0051225 6 5 0,000 0,018294 0,07335893 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,018294 0,07323687 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,018294 0,07311521 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,018294 0,07299396 ! drug metabolic process GO:0017144 6 5 0,000 0,018294 0,07287311 ! phospholipid scrambling GO:0017121 8 5 0,000 0,018294 0,07275266 ! organ regeneration GO:0031100 7 5 0,000 0,018294 0,0726326 ! carnitine metabolic process GO:0009437 7 5 0,000 0,018294 0,07251295 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,018294 0,07239368 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,018294 0,07227481 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 0,01883089 0,07427399 ! lipid modification GO:0030258 97 57 1,000 0,01883089 0,07415243 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01883089 0,07403126 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,01883089 0,07391049 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,0194571 0,07624393 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,02009197 0,07860372 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,02073545 0,08098945 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 0,02073545 0,08085819 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,02138747 0,08326577 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0219128 0,08517318 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0219128 0,0850358 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,0219128 0,08489887 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,0219128 0,08476237 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0219128 0,08462632 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,0219128 0,0844907 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,0219128 0,08435551 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0219128 0,08422076 ! sleep GO:0030431 13 6 0,000 0,0219128 0,08408644 ! response to oxygen radical GO:0000305 11 6 0,000 0,0219128 0,08395254 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,0219128 0,08381907 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,0219128 0,08368603 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,0219128 0,0835534 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,0219128 0,0834212 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0219128 0,08328941 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,0219128 0,08315804 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,0219128 0,08302708 ! forebrain regionalization GO:0021871 8 6 0,000 0,0219128 0,08289653 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0219128 0,0827664 ! male meiosis GO:0007140 7 6 0,000 0,0219128 0,08263667 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0219128 0,08250735 ! response to zinc ion GO:0010043 9 6 0,000 0,0219128 0,08237843 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0219128 0,08224992 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,0219128 0,0821218 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,0219128 0,08199408 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0219128 0,08186676 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0219128 0,08173984 ! malate metabolic process GO:0006108 11 6 0,000 0,0219128 0,08161331 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,0219128 0,08148717 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,0219128 0,08136141 ! protein refolding GO:0042026 15 6 0,000 0,0219128 0,08123605 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0219128 0,08111107 ! opsonization GO:0008228 8 6 0,000 0,0219128 0,08098648 ! mating behavior GO:0007617 7 6 0,000 0,0219128 0,08086226 ! neuron remodeling GO:0016322 15 6 0,000 0,0219128 0,08073843 ! erythrocyte maturation GO:0043249 7 6 0,000 0,0219128 0,08061498 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,0219128 0,0804919 ! equilibrioception GO:0050957 14 6 0,000 0,0219128 0,0803692 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,0219128 0,08024687 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,0219128 0,08012492 ! photoreceptor cell development GO:0042461 10 6 0,000 0,0219128 0,08000333 GO:0046530|photoreceptor cell differentiation, ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0219128 0,07988211 ! response to interferon-gamma GO:0034341 15 6 0,000 0,0219128 0,07976126 ! toxin metabolic process GO:0009404 11 6 0,000 0,0219128 0,07964078 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0219128 0,07952066 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,0219128 0,0794009 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,0219128 0,0792815 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,0219128 0,07916246 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,0219128 0,07904377 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,0219128 0,07892544 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,0219128 0,07880747 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,0219128 0,07868984 ! thymic T cell selection GO:0045061 12 6 0,000 0,0219128 0,07857257 ! protein lipoylation GO:0009249 10 6 0,000 0,0219128 0,07845565 ! cysteine metabolic process GO:0006534 10 6 0,000 0,0219128 0,07833907 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0219128 0,07822284 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,0219128 0,07810696 ! glutamate catabolic process GO:0006538 10 6 0,000 0,0219128 0,07799141 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,0219128 0,07787621 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,0219128 0,07776135 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,0219128 0,07764683 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,0219128 0,07753264 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0219128 0,07741879 ! hyperosmotic response GO:0006972 9 6 0,000 0,0219128 0,07730527 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,0219128 0,07719209 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,0219128 0,07707923 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0219128 0,07696671 ! urea metabolic process GO:0019627 7 6 0,000 0,0219128 0,07685451 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0219128 0,07674264 ! neutrophil activation GO:0042119 8 6 0,000 0,0219128 0,0766311 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0219128 0,07651988 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,0219128 0,07640898 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0219128 0,0762984 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,0219128 0,07618814 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0219128 0,0760782 ! neuron apoptosis GO:0051402 9 6 0,000 0,0219128 0,07596858 ! nucleoside salvage GO:0043174 9 6 0,000 0,0219128 0,07585927 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,0219128 0,07575028 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,0219128 0,0756416 ! T cell mediated immunity GO:0002456 16 6 0,000 0,0219128 0,07553323 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0219128 0,07542517 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,0219128 0,07531742 ! carnitine transport GO:0015879 10 6 0,000 0,0219128 0,07520998 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,0219128 0,07510284 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0219128 0,07499601 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,0219128 0,07488948 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,0219128 0,07478326 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,0219128 0,07467733 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,0219128 0,07457171 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,0219128 0,07446638 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,0219128 0,07436135 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,0219128 0,07425661 ! establishment of spindle localization GO:0051293 12 6 0,000 0,0219128 0,07415217 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,0219128 0,07404803 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0219128 0,07394417 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,0219128 0,07384061 ! neural nucleus development GO:0048857 14 6 0,000 0,0219128 0,07373734 ! response to UV-C GO:0010225 11 6 0,000 0,0219128 0,07363435 ! astrocyte development GO:0014002 15 6 0,000 0,0219128 0,07353165 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,0219128 0,07342924 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0219128 0,07332712 ! interaction with symbiont GO:0051702 13 6 0,000 0,0219128 0,07322527 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0219128 0,07312371 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,0219128 0,07302243 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,0219128 0,07292143 ! response to copper ion GO:0046688 10 6 0,000 0,0219128 0,07282071 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,0219128 0,07272027 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0219128 0,0726201 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,0219128 0,07252021 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0219128 0,0724206 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,0219128 0,07232126 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0219128 0,07222219 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,0219128 0,07212339 ! hair follicle maturation GO:0048820 7 6 0,000 0,0219128 0,07202486 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0219128 0,0719266 ! Schwann cell development GO:0014044 15 6 0,000 0,0219128 0,0718286 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,0219128 0,07173088 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,0219128 0,07163342 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,0219128 0,07153622 ! subpallium development GO:0021544 10 6 0,000 0,0219128 0,07143929 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,0219128 0,07134262 ! histone ubiquitination GO:0016574 8 6 0,000 0,0219128 0,07124621 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,0219128 0,07115006 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0219128 0,07105417 ! G2 phase GO:0051319 16 6 0,000 0,0219128 0,07095854 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,0219128 0,07086317 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0219128 0,07076805 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,0219128 0,07067318 ! membrane to membrane docking GO:0022614 14 6 0,000 0,0219128 0,07057858 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0219128 0,07048422 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,0219128 0,07039011 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0219128 0,07029626 ! receptor internalization GO:0031623 10 6 0,000 0,0219128 0,07020266 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,0219128 0,0701093 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,0219128 0,0700162 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0219128 0,06992334 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 14 6 0,000 0,0219128 0,06983072 ! protein destabilization GO:0031648 9 6 0,000 0,0219128 0,06973835 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,0219128 0,06964623 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,0219128 0,06955435 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,0219128 0,06946271 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,0219128 0,06937131 ! progesterone metabolic process GO:0042448 10 6 0,000 0,0219128 0,06928015 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,0219128 0,06918923 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,0219128 0,06909855 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,0219128 0,06900811 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,0219128 0,0689179 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0219128 0,06882793 ! determination of adult lifespan GO:0008340 15 6 0,000 0,0219128 0,0687382 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,0219128 0,06864869 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,0219128 0,06855942 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0219128 0,06847038 ! catecholamine transport GO:0051937 9 6 0,000 0,0219128 0,06838158 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,0219128 0,068293 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0219128 0,06820465 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,0219128 0,06811653 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,0219128 0,06802864 ! maternal placenta development GO:0001893 12 6 0,000 0,0219128 0,06794097 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,0219128 0,06785353 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0219128 0,06776632 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,0219128 0,06767933 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,0219128 0,06759256 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,0219128 0,06750601 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,0219128 0,06741969 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,0219128 0,06733358 ! ear development GO:0043583 103 62 1,000 0,02204795 0,06766245 ! detection of external stimulus GO:0009581 91 63 1,000 0,02271682 0,06962632 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,02407946 0,07370887 ! activation of MAPK activity GO:0000187 115 67 1,000 0,02547484 0,07788114 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,02547484 0,07778231 ! adaptive immune response GO:0002250 119 67 1,000 0,02547484 0,07768373 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 1,000 0,02547484 0,07758539 ! tRNA transcription GO:0009304 14 7 0,000 0,02551838 0,07761975 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02551838 0,07752175 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02551838 0,07742399 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02551838 0,07732648 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02551838 0,07722922 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02551838 0,07713219 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02551838 0,07703542 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02551838 0,07693888 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02551838 0,07684259 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02551838 0,07674653 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02551838 0,07665072 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02551838 0,07655514 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02551838 0,07645981 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02551838 0,07636471 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02551838 0,07626985 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02551838 0,07617522 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02551838 0,07608083 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02551838 0,07598667 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02551838 0,07589274 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02551838 0,07579904 ! glycolipid transport GO:0046836 10 7 0,000 0,02551838 0,07570558 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02551838 0,07561235 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02551838 0,07551934 ! neuron adhesion GO:0007158 12 7 0,000 0,02551838 0,07542657 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02551838 0,07533402 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02551838 0,0752417 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02551838 0,0751496 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02551838 0,07505773 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02551838 0,07496609 ! pericardium development GO:0060039 14 7 0,000 0,02551838 0,07487467 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02551838 0,07478347 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02551838 0,07469249 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02551838 0,07460173 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02551838 0,0745112 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02551838 0,07442088 ! lipoprotein transport GO:0042953 14 7 0,000 0,02551838 0,07433078 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02551838 0,0742409 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02551838 0,07415124 ! rhythmic behavior GO:0007622 15 7 0,000 0,02551838 0,07406179 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02551838 0,07397256 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02551838 0,07388355 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02551838 0,07379474 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02551838 0,07370615 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02551838 0,07361778 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02551838 0,07352961 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02551838 0,07344166 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02551838 0,07335391 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02551838 0,07326638 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02551838 0,07317905 GO:0045911|positive regulation of DNA recombination, ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02551838 0,07309194 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02551838 0,07300503 ! spinal cord patterning GO:0021511 13 7 0,000 0,02551838 0,07291832 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02551838 0,07283182 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02551838 0,07274553 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02551838 0,07265944 ! adrenal gland development GO:0030325 17 7 0,000 0,02551838 0,07257355 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02551838 0,07248787 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02551838 0,07240239 ! ovulation GO:0030728 9 7 0,000 0,02551838 0,07231711 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02551838 0,07223203 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02551838 0,07214715 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02551838 0,07206247 ! microtubule nucleation GO:0007020 20 7 0,000 0,02551838 0,07197799 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02551838 0,07189371 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02551838 0,07180962 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02551838 0,07172573 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02551838 0,07164204 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02551838 0,07155854 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02551838 0,07147523 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02551838 0,07139212 ! galactose metabolic process GO:0006012 13 7 0,000 0,02551838 0,07130921 ! vesicle fusion GO:0006906 17 7 0,000 0,02551838 0,07122648 ! response to dietary excess GO:0002021 8 7 0,000 0,02551838 0,07114395 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02551838 0,0710616 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02551838 0,07097945 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02551838 0,07089749 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02551838 0,07081572 ! organ growth GO:0035265 15 7 0,000 0,02551838 0,07073413 ! purine salvage GO:0043101 10 7 0,000 0,02551838 0,07065273 ! nucleoside transport GO:0015858 8 7 0,000 0,02551838 0,07057152 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02551838 0,0704905 ! parturition GO:0007567 14 7 0,000 0,02551838 0,07040966 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02551838 0,07032901 ! rRNA modification GO:0000154 14 7 0,000 0,02551838 0,07024854 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02551838 0,07016826 ! spindle checkpoint GO:0031577 15 7 0,000 0,02551838 0,07008816 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02551838 0,07000824 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02551838 0,0699285 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02551838 0,06984895 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02551838 0,06976958 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02551838 0,06969038 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02551838 0,06961137 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02551838 0,06953253 ! fibrinolysis GO:0042730 10 7 0,000 0,02551838 0,06945388 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02551838 0,0693754 ! eating behavior GO:0042755 7 7 0,000 0,02551838 0,06929709 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02551838 0,06921897 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02551838 0,06914102 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02551838 0,06906325 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02551838 0,06898565 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02551838 0,06890822 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02551838 0,06883097 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02551838 0,06875389 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02551838 0,06867699 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02551838 0,06860025 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02551838 0,06852369 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02551838 0,0684473 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02551838 0,06837108 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02551838 0,06829502 ! regulation of meiosis GO:0040020 12 7 0,000 0,02551838 0,06821914 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02551838 0,06814343 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02551838 0,06806788 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02551838 0,0679925 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02551838 0,06791729 ! transcription termination GO:0006353 13 7 0,000 0,02551838 0,06784224 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,02551838 0,06776736 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02551838 0,06769264 ! anaphase GO:0051322 17 7 0,000 0,02551838 0,06761809 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02551838 0,0675437 ! axonal fasciculation GO:0007413 18 7 0,000 0,02551838 0,06746948 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02551838 0,06739542 GO:0045839|negative regulation of mitosis, ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02551838 0,06732152 ! diuresis GO:0030146 12 7 0,000 0,02551838 0,06724778 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02551838 0,06717421 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02551838 0,06710079 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02551838 0,06702754 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02551838 0,06695445 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02551838 0,06688151 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02551838 0,06680873 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02551838 0,06673612 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02551838 0,06666365 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02551838 0,06659135 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02551838 0,0665192 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02551838 0,06644721 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02551838 0,06637538 ! lymph node development GO:0048535 10 7 0,000 0,02551838 0,0663037 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02551838 0,06623217 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02551838 0,0661608 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02551838 0,06608959 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02551838 0,06601852 ! adult feeding behavior GO:0008343 9 7 0,000 0,02551838 0,06594761 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02551838 0,06587685 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02551838 0,06580624 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02551838 0,06573579 ! muscle adaptation GO:0043500 14 7 0,000 0,02551838 0,06566548 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02551838 0,06559533 ! retina homeostasis GO:0001895 12 7 0,000 0,02551838 0,06552532 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02551838 0,06545546 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02551838 0,06538576 ! protein prenylation GO:0018342 18 7 0,000 0,02551838 0,0653162 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02551838 0,06524679 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02551838 0,06517752 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02551838 0,06510841 ! regulation of lipase activity GO:0060191 130 68 1,000 0,02618464 0,06673754 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,02618464 0,06666691 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,02690241 0,068422 ! urogenital system development GO:0001655 137 69 1,000 0,02690241 0,06834975 ! reproductive structure development GO:0048608 113 71 1,000 0,02836165 0,07198114 ! B cell activation GO:0042113 160 71 1,000 0,02836165 0,07190529 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,02910296 0,07370709 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,02910296 0,07362958 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,02910296 0,07355224 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02911079 0,07349482 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02911079 0,07341778 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02911079 0,0733409 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02911079 0,07326419 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02911079 0,07318763 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02911079 0,07311124 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02911079 0,073035 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02911079 0,07295892 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02911079 0,072883 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02911079 0,07280724 ! meiotic prophase I GO:0007128 13 8 0,000 0,02911079 0,07273163 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02911079 0,07265619 ! oligopeptide transport GO:0006857 15 8 0,000 0,02911079 0,0725809 ! UTP metabolic process GO:0046051 8 8 0,000 0,02911079 0,07250576 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02911079 0,07243078 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02911079 0,07235595 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02911079 0,07228128 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02911079 0,07220677 ! succinate metabolic process GO:0006105 14 8 0,000 0,02911079 0,0721324 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02911079 0,07205819 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02911079 0,07198414 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02911079 0,07191023 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02911079 0,07183648 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02911079 0,07176287 ! reflex GO:0060004 16 8 0,000 0,02911079 0,07168942 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02911079 0,07161612 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02911079 0,07154297 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02911079 0,07146996 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02911079 0,07139711 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02911079 0,0713244 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02911079 0,07125185 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02911079 0,07117944 ! pigment granule organization GO:0048753 16 8 0,000 0,02911079 0,07110717 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02911079 0,07103505 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02911079 0,07096308 ! histidine metabolic process GO:0006547 16 8 0,000 0,02911079 0,07089126 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02911079 0,07081958 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02911079 0,07074804 ! glycine catabolic process GO:0006546 13 8 0,000 0,02911079 0,07067665 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02911079 0,07060541 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02911079 0,0705343 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02911079 0,07046334 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02911079 0,07039253 ! melanin metabolic process GO:0006582 15 8 0,000 0,02911079 0,07032185 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02911079 0,07025132 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02911079 0,07018093 ! macrophage activation GO:0042116 12 8 0,000 0,02911079 0,07011067 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02911079 0,07004056 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02911079 0,06997059 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02911079 0,06990076 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02911079 0,06983107 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02911079 0,06976152 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02911079 0,0696921 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02911079 0,06962283 ! osteoblast development GO:0002076 16 8 0,000 0,02911079 0,06955369 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02911079 0,06948469 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02911079 0,06941582 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02911079 0,06934709 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02911079 0,0692785 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02911079 0,06921004 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02911079 0,06914172 ! response to UV-B GO:0010224 16 8 0,000 0,02911079 0,06907353 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02911079 0,06900548 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02911079 0,06893756 ! intermediate filament organization GO:0045109 12 8 0,000 0,02911079 0,06886978 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02911079 0,06880213 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02911079 0,06873461 ! cellular extravasation GO:0045123 12 8 0,000 0,02911079 0,06866722 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02911079 0,06859996 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02911079 0,06853284 ! response to antibiotic GO:0046677 11 8 0,000 0,02911079 0,06846585 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02911079 0,06839899 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02911079 0,06833226 ! DNA topological change GO:0006265 12 8 0,000 0,02911079 0,06826566 ! response to tropane GO:0014073 15 8 0,000 0,02911079 0,06819919 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02911079 0,06813284 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,02911079 0,06806663 ! melanosome transport GO:0032402 13 8 0,000 0,02911079 0,06800055 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02911079 0,06793459 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02911079 0,06786876 ! mast cell activation GO:0045576 14 8 0,000 0,02911079 0,06780306 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02911079 0,06773749 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02911079 0,06767204 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02911079 0,06760672 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02911079 0,06754153 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02911079 0,06747646 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02911079 0,06741152 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02911079 0,0673467 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02911079 0,067282 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02911079 0,06721743 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02911079 0,06715299 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02911079 0,06708866 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02911079 0,06702446 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02911079 0,06696039 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02911079 0,06689643 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02911079 0,0668326 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02911079 0,06676889 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02911079 0,0667053 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02911079 0,06664183 ! hormone catabolic process GO:0042447 17 8 0,000 0,02911079 0,06657848 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02911079 0,06651526 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02911079 0,06645215 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02911079 0,06638916 ! ATP catabolic process GO:0006200 11 8 0,000 0,02911079 0,06632629 ! blastocyst growth GO:0001832 19 8 0,000 0,02911079 0,06626354 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02911079 0,06620091 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02911079 0,0661384 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02911079 0,066076 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02911079 0,06601373 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02911079 0,06595157 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02911079 0,06588952 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02911079 0,0658276 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02911079 0,06576579 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02911079 0,06570409 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02911079 0,06564252 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02911079 0,06558105 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02911079 0,0655197 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02911079 0,06545847 ! axon guidance GO:0007411 139 73 1,000 0,029852 0,06706247 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,03060868 0,06869821 GO:0090046|regulation of transcription regulator activity, ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,03060868 0,06863418 ! eye development GO:0001654 143 74 1,000 0,03060868 0,06857028 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,03137294 0,07021702 ! regulation of developmental growth GO:0048638 15 9 0,000 0,03269008 0,07309696 ! axon extension GO:0048675 15 9 0,000 0,03269008 0,07302909 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03269008 0,07296134 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,03269008 0,07289372 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03269008 0,07282623 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03269008 0,07275886 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03269008 0,07269161 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03269008 0,07262449 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03269008 0,0725575 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03269008 0,07249062 ! phosphate transport GO:0006817 19 9 0,000 0,03269008 0,07242387 ! reproductive behavior GO:0019098 19 9 0,000 0,03269008 0,07235724 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03269008 0,07229074 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03269008 0,07222436 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03269008 0,0721581 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03269008 0,07209196 ! GTP metabolic process GO:0046039 9 9 0,000 0,03269008 0,07202594 ! RNA methylation GO:0001510 15 9 0,000 0,03269008 0,07196004 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03269008 0,07189426 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03269008 0,07182861 ! artery development GO:0060840 24 9 0,000 0,03269008 0,07176307 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03269008 0,07169765 ! regulation of glycolysis GO:0006110 21 9 0,000 0,03269008 0,07163235 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03269008 0,07156717 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,03269008 0,07150211 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03269008 0,07143717 ! chemosensory behavior GO:0007635 20 9 0,000 0,03269008 0,07137235 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,03269008 0,07130764 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03269008 0,07124305 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03269008 0,07117857 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03269008 0,07111422 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03269008 0,07104998 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03269008 0,07098585 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03269008 0,07092184 ! protein targeting to ER GO:0045047 22 9 0,000 0,03269008 0,07085795 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03269008 0,07079417 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,03269008 0,07073051 ! T cell selection GO:0045058 23 9 0,000 0,03269008 0,07066696 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03269008 0,07060352 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03269008 0,0705402 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,03269008 0,07047699 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03269008 0,0704139 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03269008 0,07035092 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03269008 0,07028805 ! mannose metabolic process GO:0006013 13 9 0,000 0,03269008 0,07022529 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03269008 0,07016264 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03269008 0,07010011 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03269008 0,07003769 ! receptor clustering GO:0043113 18 9 0,000 0,03269008 0,06997538 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03269008 0,06991318 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03269008 0,06985109 ! retinol metabolic process GO:0042572 18 9 0,000 0,03269008 0,06978911 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03269008 0,06972724 ! behavioral fear response GO:0001662 22 9 0,000 0,03269008 0,06966548 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03269008 0,06960383 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03269008 0,06954229 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03269008 0,06948085 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,03269008 0,06941953 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03269008 0,06935831 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03269008 0,0692972 ! segment specification GO:0007379 13 9 0,000 0,03269008 0,0692362 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03269008 0,06917531 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03269008 0,06911452 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03269008 0,06905384 ! response to amine stimulus GO:0014075 13 9 0,000 0,03269008 0,06899327 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03269008 0,0689328 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03269008 0,06887244 ! erythrocyte development GO:0048821 15 9 0,000 0,03269008 0,06881218 ! gas homeostasis GO:0033483 16 9 0,000 0,03269008 0,06875203 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03269008 0,06869199 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,03269008 0,06863205 ! renal water homeostasis GO:0003091 14 9 0,000 0,03269008 0,06857221 ! postreplication repair GO:0006301 22 9 0,000 0,03269008 0,06851248 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03269008 0,06845285 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03269008 0,06839333 ! icosanoid secretion GO:0032309 15 9 0,000 0,03269008 0,0683339 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,03269008 0,06827459 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03269008 0,06821537 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03269008 0,06815626 ! regulation of cell division GO:0051302 15 9 0,000 0,03269008 0,06809725 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03269008 0,06803834 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03269008 0,06797954 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03269008 0,06792083 ! sterol catabolic process GO:0016127 11 9 0,000 0,03269008 0,06786223 GO:0006707|cholesterol catabolic process, ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03269008 0,06780373 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03269008 0,06774533 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03269008 0,06768703 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,03269008 0,06762883 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,03269008 0,06757073 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03269008 0,06751272 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03269008 0,06745482 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03269008 0,06739702 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03269008 0,06733932 ! purine base metabolic process GO:0006144 21 9 0,000 0,03269008 0,06728171 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03269008 0,06722421 ! pigment granule transport GO:0051904 17 9 0,000 0,03269008 0,0671668 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03269008 0,06710949 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03269008 0,06705228 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03269008 0,06699517 ! mitochondrion localization GO:0051646 15 9 0,000 0,03269008 0,06693815 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,03292395 0,06735972 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,03292395 0,06730249 ! blood coagulation GO:0007596 146 78 1,000 0,03371058 0,06885199 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,03371058 0,06879359 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,03450452 0,07035413 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,03450452 0,07029456 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,03450452 0,07023509 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,03450452 0,07017572 ! muscle cell differentiation GO:0042692 159 80 1,000 0,03530573 0,07174458 ! T cell activation GO:0042110 168 81 1,000 0,03611413 0,0733254 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,03611413 0,07326358 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03625629 0,07348999 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,03625629 0,07342813 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03625629 0,07336638 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03625629 0,07330472 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,03625629 0,07324318 ! synapsis GO:0007129 13 10 0,000 0,03625629 0,07318173 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03625629 0,07312039 ! N-glycan processing GO:0006491 20 10 0,000 0,03625629 0,07305915 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03625629 0,07299801 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03625629 0,07293697 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03625629 0,07287604 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03625629 0,07281521 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,03625629 0,07275448 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03625629 0,07269385 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03625629 0,07263332 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03625629 0,0725729 ! androgen metabolic process GO:0008209 17 10 0,000 0,03625629 0,07251257 ! phospholipid efflux GO:0033700 16 10 0,000 0,03625629 0,07245234 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03625629 0,07239222 ! pathogenesis GO:0009405 13 10 0,000 0,03625629 0,07233219 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03625629 0,07227226 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03625629 0,07221244 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03625629 0,07215271 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03625629 0,07209308 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03625629 0,07203354 ! endoderm development GO:0007492 16 10 0,000 0,03625629 0,07197411 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03625629 0,07191477 ! arginine catabolic process GO:0006527 13 10 0,000 0,03625629 0,07185554 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03625629 0,0717964 ! proline metabolic process GO:0006560 13 10 0,000 0,03625629 0,07173735 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03625629 0,07167841 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03625629 0,07161956 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03625629 0,07156081 ! V(D)J recombination GO:0033151 28 10 0,000 0,03625629 0,07150215 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03625629 0,07144359 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03625629 0,07138512 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 18 10 0,000 0,03625629 0,07132676 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03625629 0,07126848 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03625629 0,0712103 ! multicellular organism growth GO:0035264 18 10 0,000 0,03625629 0,07115222 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03625629 0,07109423 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03625629 0,07103634 ! epithelial cell development GO:0002064 20 10 0,000 0,03625629 0,07097854 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03625629 0,07092083 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03625629 0,07086322 ! macroautophagy GO:0016236 17 10 0,000 0,03625629 0,0708057 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03625629 0,07074827 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03625629 0,07069094 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03625629 0,0706337 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03625629 0,07057655 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03625629 0,0705195 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03625629 0,07046254 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03625629 0,07040567 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03625629 0,07034889 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03625629 0,0702922 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03625629 0,07023561 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03625629 0,0701791 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03625629 0,07012269 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03625629 0,07006636 ! melanosome localization GO:0032400 16 10 0,000 0,03625629 0,07001013 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03625629 0,06995399 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03625629 0,06989793 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03625629 0,06984197 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03625629 0,0697861 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03625629 0,06973031 ! mRNA cleavage GO:0006379 17 10 0,000 0,03625629 0,06967462 ! protein sumoylation GO:0016925 15 10 0,000 0,03625629 0,06961901 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03625629 0,06956349 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03625629 0,06950807 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03625629 0,06945272 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03625629 0,06939747 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03625629 0,06934231 ! prophase GO:0051324 15 10 0,000 0,03625629 0,06928723 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03625629 0,06923224 ! apical protein localization GO:0045176 15 10 0,000 0,03625629 0,06917734 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03625629 0,06912252 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03625629 0,06906779 ! midbrain development GO:0030901 13 10 0,000 0,03625629 0,06901315 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03625629 0,06895859 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03625629 0,06890412 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03625629 0,06884974 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03625629 0,06879544 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03625629 0,06874123 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03625629 0,0686871 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03625629 0,06863306 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,03625629 0,06857911 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,03625629 0,06852523 ! oocyte development GO:0048599 17 10 0,000 0,03625629 0,06847145 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03625629 0,06841774 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03625629 0,06836412 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03625629 0,06831059 ! activation of innate immune response GO:0002218 12 10 0,000 0,03625629 0,06825714 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03625629 0,06820377 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03625629 0,06815049 ! response to nicotine GO:0035094 20 10 0,000 0,03625629 0,06809728 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03625629 0,06804417 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03625629 0,06799113 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,03692967 0,06919999 ! hemostasis GO:0007599 158 84 1,000 0,0385819 0,07223974 ! regulation of ligase activity GO:0051340 142 84 1,000 0,0385819 0,07218356 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,03941847 0,07369141 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03980946 0,07436457 ! respiratory burst GO:0045730 17 11 0,000 0,03980946 0,07430688 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03980946 0,07424928 ! neuron fate specification GO:0048665 17 11 0,000 0,03980946 0,07419177 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03980946 0,07413434 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03980946 0,07407701 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03980946 0,07401976 ! thyroid gland development GO:0030878 26 11 0,000 0,03980946 0,0739626 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03980946 0,07390553 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03980946 0,07384855 ! response to pain GO:0048265 24 11 0,000 0,03980946 0,07379166 ! T cell proliferation GO:0042098 26 11 0,000 0,03980946 0,07373485 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03980946 0,07367813 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,03980946 0,0736215 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03980946 0,07356495 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03980946 0,0735085 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03980946 0,07345212 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03980946 0,07339584 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03980946 0,07333964 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03980946 0,07328353 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03980946 0,0732275 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03980946 0,07317156 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03980946 0,0731157 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,03980946 0,07305993 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03980946 0,07300425 ! UV protection GO:0009650 19 11 0,000 0,03980946 0,07294864 ! adult heart development GO:0007512 14 11 0,000 0,03980946 0,07289313 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03980946 0,0728377 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03980946 0,07278235 ! temperature homeostasis GO:0001659 17 11 0,000 0,03980946 0,07272708 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03980946 0,0726719 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03980946 0,07261681 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03980946 0,0725618 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03980946 0,07250687 ! regulation of organ growth GO:0046620 13 11 0,000 0,03980946 0,07245202 ! pigment granule localization GO:0051875 20 11 0,000 0,03980946 0,07239726 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03980946 0,07234258 ! vasoconstriction GO:0042310 18 11 0,000 0,03980946 0,07228798 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03980946 0,07223346 ! embryonic axis specification GO:0000578 18 11 0,000 0,03980946 0,07217903 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03980946 0,07212468 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03980946 0,07207041 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03980946 0,07201622 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03980946 0,07196211 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03980946 0,07190809 ! zymogen activation GO:0031638 15 11 0,000 0,03980946 0,07185414 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03980946 0,07180028 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03980946 0,07174649 ! nucleosome positioning GO:0016584 15 11 0,000 0,03980946 0,07169279 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03980946 0,07163917 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03980946 0,07158563 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03980946 0,07153217 ! acid secretion GO:0046717 18 11 0,000 0,03980946 0,07147878 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03980946 0,07142548 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03980946 0,07137226 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03980946 0,07131911 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03980946 0,07126605 ! oocyte differentiation GO:0009994 18 11 0,000 0,03980946 0,07121306 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03980946 0,07116016 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03980946 0,07110733 ! cholesterol efflux GO:0033344 19 11 0,000 0,03980946 0,07105458 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03980946 0,07100191 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03980946 0,07094931 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03980946 0,07089679 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03980946 0,07084436 ! embryonic gut development GO:0048566 15 11 0,000 0,03980946 0,070792 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03980946 0,07073971 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03980946 0,07068751 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03980946 0,07063538 ! defense response to fungus GO:0050832 13 11 0,000 0,03980946 0,07058332 ! developmental induction GO:0031128 19 11 0,000 0,03980946 0,07053135 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03980946 0,07047945 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03980946 0,07042762 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03980946 0,07037588 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03980946 0,07032421 ! regulation of embryonic development GO:0045995 27 11 0,000 0,03980946 0,07027261 ! nucleus localization GO:0051647 19 11 0,000 0,03980946 0,07022109 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03980946 0,07016965 ! regulation of protein transport GO:0051223 154 87 1,000 0,04111221 0,07241287 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 1,000 0,04196926 0,07386835 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,04334966 0,07624217 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,04334966 0,07618647 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,04334966 0,07613086 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,04334966 0,07607533 ! virus-host interaction GO:0019048 29 12 0,000 0,04334966 0,07601989 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,04334966 0,07596452 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,04334966 0,07590923 ! mating GO:0007618 17 12 0,000 0,04334966 0,07585402 ! protein complex disassembly GO:0043241 27 12 0,000 0,04334966 0,0757989 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04334966 0,07574385 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,04334966 0,07568888 ! hippocampus development GO:0021766 26 12 0,000 0,04334966 0,075634 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,04334966 0,07557919 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,04334966 0,07552446 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,04334966 0,07546981 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,04334966 0,07541524 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,04334966 0,07536075 ! drug transport GO:0015893 16 12 0,000 0,04334966 0,07530634 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,04334966 0,07525201 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,04334966 0,07519775 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,04334966 0,07514358 ! polyamine metabolic process GO:0006595 17 12 0,000 0,04334966 0,07508948 ! mitotic spindle organization GO:0007052 21 12 0,000 0,04334966 0,07503545 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,04334966 0,07498151 ! forebrain cell migration GO:0021885 21 12 0,000 0,04334966 0,07492765 ! asymmetric protein localization GO:0008105 20 12 0,000 0,04334966 0,07487386 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,04334966 0,07482015 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,04334966 0,07476651 ! entry into host cell GO:0030260 32 12 0,000 0,04334966 0,07471295 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,04334966 0,07465947 ! monoamine transport GO:0015844 18 12 0,000 0,04334966 0,07460607 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04334966 0,07455274 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,04334966 0,07449949 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,04334966 0,07444631 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,04334966 0,07439321 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04334966 0,07434019 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,04334966 0,07428724 ! protein homotetramerization GO:0051289 21 12 0,000 0,04334966 0,07423436 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,04334966 0,07418157 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,04334966 0,07412884 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04334966 0,07407619 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,04334966 0,07402362 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,04334966 0,07397112 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04334966 0,0739187 ! cranial nerve development GO:0021545 20 12 0,000 0,04334966 0,07386635 ! fucose catabolic process GO:0019317 22 12 0,000 0,04334966 0,07381407 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,04334966 0,07376187 ! histone methylation GO:0016571 26 12 0,000 0,04334966 0,07370974 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,04334966 0,07365769 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04334966 0,0736057 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,04334966 0,0735538 ! T cell homeostasis GO:0043029 25 12 0,000 0,04334966 0,07350196 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,04334966 0,0734502 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,04334966 0,07339851 ! spleen development GO:0048536 22 12 0,000 0,04334966 0,07334689 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,04334966 0,07329535 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,04334966 0,07324388 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,04334966 0,07319248 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,04334966 0,07314115 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,04334966 0,0730899 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,04334966 0,07303871 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,04334966 0,0729876 ! response to cold GO:0009409 17 12 0,000 0,04334966 0,07293656 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,04334966 0,07288559 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,04334966 0,07283469 ! sex differentiation GO:0007548 145 90 1,000 0,04370341 0,0733778 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,04635386 0,07777364 GO:0010498|proteasomal protein catabolic process, ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,04635386 0,07771944 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04687692 0,07854169 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04687692 0,07848704 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04687692 0,07843246 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04687692 0,07837795 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,04687692 0,07832352 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04687692 0,07826917 ! lipid localization GO:0010876 28 13 0,000 0,04687692 0,07821489 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,04687692 0,07816069 ! organelle fusion GO:0048284 32 13 0,000 0,04687692 0,07810656 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04687692 0,07805251 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,04687692 0,07799853 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,04687692 0,07794462 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04687692 0,0778908 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04687692 0,07783704 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,04687692 0,07778336 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,04687692 0,07772975 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04687692 0,07767622 ! methionine metabolic process GO:0006555 27 13 0,000 0,04687692 0,07762276 ! plasma membrane organization GO:0007009 24 13 0,000 0,04687692 0,07756938 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04687692 0,07751606 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04687692 0,07746282 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04687692 0,07740966 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,04687692 0,07735657 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,04687692 0,07730354 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04687692 0,0772506 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,04687692 0,07719772 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,04687692 0,07714492 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,04687692 0,07709219 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04687692 0,07703953 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04687692 0,07698694 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,04687692 0,07693443 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04687692 0,07688198 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,04687692 0,07682961 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04687692 0,07677731 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04687692 0,07672508 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04687692 0,07667292 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04687692 0,07662084 ! ribosome assembly GO:0042255 17 13 0,000 0,04687692 0,07656882 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04687692 0,07651687 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04687692 0,076465 ! chromatin silencing GO:0006342 26 13 0,000 0,04687692 0,07641319 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04687692 0,07636146 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04687692 0,07630979 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04687692 0,0762582 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,04687692 0,07620667 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04687692 0,07615521 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04687692 0,07610383 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04687692 0,07605251 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04687692 0,07600126 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,04687692 0,07595008 ! embryonic placenta development GO:0001892 23 13 0,000 0,04687692 0,07589897 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,04687692 0,07584793 ! insulin secretion GO:0030073 23 13 0,000 0,04687692 0,07579696 ! actin filament polymerization GO:0030041 24 13 0,000 0,04687692 0,07574605 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,04687692 0,07569522 ! acrosome reaction GO:0007340 18 13 0,000 0,04687692 0,07564445 ! transcription initiation GO:0006352 153 94 1,000 0,04725024 0,07619577 ! detection of stimulus GO:0051606 151 96 1,000 0,04906199 0,0790644 ! regulation of protein localization GO:0032880 176 97 1,000 0,04997724 0,08048544 ! rRNA transcription GO:0009303 25 14 0,000 0,05039129 0,08109796 ! lactation GO:0007595 26 14 0,000 0,05039129 0,08104375 ! reproductive cellular process GO:0048610 20 14 0,000 0,05039129 0,08098961 ! tRNA modification GO:0006400 20 14 0,000 0,05039129 0,08093555 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,05039129 0,08088156 ! regulation of S phase GO:0033261 23 14 0,000 0,05039129 0,08082763 ! water transport GO:0006833 21 14 0,000 0,05039129 0,08077379 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,05039129 0,08072001 ! non-recombinational repair GO:0000726 25 14 0,000 0,05039129 0,0806663 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,05039129 0,08061267 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,05039129 0,0805591 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,05039129 0,08050561 ! RNA polyadenylation GO:0043631 30 14 0,000 0,05039129 0,08045219 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,05039129 0,08039884 ! palate development GO:0060021 31 14 0,000 0,05039129 0,08034556 ! regulated secretory pathway GO:0045055 23 14 0,000 0,05039129 0,08029235 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,05039129 0,08023921 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,05039129 0,08018615 ! arginine metabolic process GO:0006525 17 14 0,000 0,05039129 0,08013315 ! organic alcohol transport GO:0015850 29 14 0,000 0,05039129 0,08008022 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,05039129 0,08002736 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,05039129 0,07997457 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,05039129 0,07992185 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,05039129 0,0798692 ! neutral amino acid transport GO:0015804 26 14 0,000 0,05039129 0,07981662 ! L-amino acid transport GO:0015807 30 14 0,000 0,05039129 0,07976411 ! bone mineralization GO:0030282 17 14 0,000 0,05039129 0,07971167 ! stem cell development GO:0048864 43 14 0,000 0,05039129 0,0796593 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,05039129 0,07960699 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,05039129 0,07955476 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05039129 0,07950259 ! cerebellum development GO:0021549 21 14 0,000 0,05039129 0,07945049 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,05039129 0,07939846 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,05039129 0,0793465 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,05039129 0,07929461 ! cofactor transport GO:0051181 26 14 0,000 0,05039129 0,07924278 ! NADP metabolic process GO:0006739 24 14 0,000 0,05039129 0,07919102 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,05039129 0,07913933 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,05039129 0,0790877 ! intestinal absorption GO:0050892 25 14 0,000 0,05039129 0,07903615 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,05039129 0,07898466 ! oxygen transport GO:0015671 21 14 0,000 0,05039129 0,07893324 ! male genitalia development GO:0030539 24 14 0,000 0,05039129 0,07888188 ! regulation of axon extension GO:0030516 37 14 0,000 0,05039129 0,07883059 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,05039129 0,07877937 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,05182622 0,08097005 GO:0060538|skeletal muscle organ development, ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05389282 0,08414415 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05389282 0,08408958 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,05389282 0,08403508 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,05389282 0,08398066 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,05389282 0,0839263 ! copper ion transport GO:0006825 20 15 0,000 0,05389282 0,08387201 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,05389282 0,0838178 ! sulfate transport GO:0008272 23 15 0,000 0,05389282 0,08376365 ! response to cAMP GO:0051591 22 15 0,000 0,05389282 0,08370958 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,05389282 0,08365557 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,05389282 0,08360163 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,05389282 0,08354777 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,05389282 0,08349397 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,05389282 0,08344024 ! response to hexose stimulus GO:0009746 22 15 0,000 0,05389282 0,08338658 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,05389282 0,08333299 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,05389282 0,08327947 ! pituitary gland development GO:0021983 29 15 0,000 0,05389282 0,08322602 ! vesicle coating GO:0006901 33 15 0,000 0,05389282 0,08317263 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,05389282 0,08311932 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,05389282 0,08306607 ! regulation of exocytosis GO:0017157 22 15 0,000 0,05389282 0,08301289 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,05389282 0,08295978 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,05389282 0,08290673 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,05389282 0,08285376 ! regulation of vasodilation GO:0042312 26 15 0,000 0,05389282 0,08280085 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,05389282 0,08274801 ! histone deacetylation GO:0016575 20 15 0,000 0,05389282 0,08269524 ! mRNA splice site selection GO:0006376 38 15 0,000 0,05389282 0,08264253 ! tissue regeneration GO:0042246 26 15 0,000 0,05389282 0,08258989 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,05389282 0,08253732 ! water homeostasis GO:0030104 27 15 0,000 0,05389282 0,08248482 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05389282 0,08243238 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,05389282 0,08238001 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,05389282 0,0823277 ! heme biosynthetic process GO:0006783 29 15 0,000 0,05389282 0,08227547 ! cell killing GO:0001906 29 15 0,000 0,05389282 0,08222329 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,05389282 0,08217119 ! detection of bacterium GO:0016045 18 15 0,000 0,05389282 0,08211915 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,05389282 0,08206717 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,05389282 0,08201526 ! peptide hormone processing GO:0016486 23 15 0,000 0,05389282 0,08196342 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,05738156 0,08721417 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,05738156 0,08715911 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,05738156 0,08710412 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,05738156 0,0870492 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,05738156 0,08699435 ! bone remodeling GO:0046849 27 16 0,000 0,05738156 0,08693957 ! filopodium assembly GO:0046847 32 16 0,000 0,05738156 0,08688485 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,05738156 0,08683021 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,05738156 0,08677563 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,05738156 0,08672112 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,05738156 0,08666669 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,05738156 0,08661231 ! startle response GO:0001964 28 16 0,000 0,05738156 0,08655801 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,05738156 0,08650378 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,05738156 0,08644961 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,05738156 0,08639551 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,05738156 0,08634148 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,05738156 0,08628752 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,05738156 0,08623362 ! protein polyubiquitination GO:0000209 34 16 0,000 0,05738156 0,08617979 ! glutamate metabolic process GO:0006536 22 16 0,000 0,05738156 0,08612603 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,05738156 0,08607234 ! response to osmotic stress GO:0006970 25 16 0,000 0,05738156 0,08601871 ! lysosomal transport GO:0007041 26 16 0,000 0,05738156 0,08596515 ! fructose metabolic process GO:0006000 25 16 0,000 0,05738156 0,08591165 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05738156 0,08585823 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,05738156 0,08580487 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,05738156 0,08575157 ! axon cargo transport GO:0008088 43 16 0,000 0,05738156 0,08569834 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,05738156 0,08564518 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,05738156 0,08559208 ! DNA replication initiation GO:0006270 27 16 0,000 0,05738156 0,08553905 ! neuron recognition GO:0008038 35 16 0,000 0,05738156 0,08548609 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,05738156 0,08543319 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,05738156 0,08538035 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,05738156 0,08532758 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,05738156 0,08527488 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,05738156 0,08522224 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,05738156 0,08516967 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,05738156 0,08511716 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05738156 0,08506471 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,05738156 0,08501233 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,05738156 0,08496002 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,05738156 0,08490777 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,05738156 0,08485558 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,06085754 0,08994057 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,06085754 0,08988536 ! metencephalon development GO:0022037 30 17 0,000 0,06085754 0,08983022 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,06085754 0,08977514 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,06085754 0,08972013 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,06085754 0,08966519 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,06085754 0,08961031 ! signal complex assembly GO:0007172 41 17 0,000 0,06085754 0,08955551 ! inositol metabolic process GO:0006020 28 17 0,000 0,06085754 0,08950076 ! gene silencing by RNA GO:0031047 36 17 0,000 0,06085754 0,08944609 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,06085754 0,08939148 ! glial cell development GO:0021782 27 17 0,000 0,06085754 0,08933694 ! limbic system development GO:0021761 36 17 0,000 0,06085754 0,08928247 ! adult walking behavior GO:0007628 33 17 0,000 0,06085754 0,08922806 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,06085754 0,08917372 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,06085754 0,08911945 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,06085754 0,08906524 ! myoblast differentiation GO:0045445 45 17 0,000 0,06085754 0,08901109 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,06085754 0,08895702 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,06085754 0,08890301 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,06085754 0,08884906 ! glycine metabolic process GO:0006544 28 17 0,000 0,06085754 0,08879518 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,06085754 0,08874136 ! NAD metabolic process GO:0019674 29 17 0,000 0,06085754 0,08868761 ! membrane budding GO:0006900 37 17 0,000 0,06085754 0,08863393 ! DNA integration GO:0015074 29 17 0,000 0,06085754 0,08858031 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,06085754 0,08852675 ! regulation of protein binding GO:0043393 33 17 0,000 0,06085754 0,08847326 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,06085754 0,08841984 ! genitalia development GO:0048806 30 17 0,000 0,06085754 0,08836648 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,06085754 0,08831318 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,06085754 0,08825995 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,06085754 0,08820678 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,06085754 0,08815367 ! steroid catabolic process GO:0006706 31 17 0,000 0,06085754 0,08810063 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,06085754 0,08804766 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,06085754 0,08799474 ! gas transport GO:0015669 25 17 0,000 0,06085754 0,08794189 ! organic cation transport GO:0015695 31 17 0,000 0,06085754 0,08788911 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,06085754 0,08783638 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,06085754 0,08778372 ! microspike assembly GO:0030035 36 17 0,000 0,06085754 0,08773113 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,06432083 0,09266821 ! neuron maturation GO:0042551 42 18 0,000 0,06432083 0,09261275 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,06432083 0,09255736 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,06432083 0,09250204 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,06432083 0,09244678 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,06432083 0,09239159 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,06432083 0,09233646 ! memory GO:0007613 31 18 0,000 0,06432083 0,0922814 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06432083 0,09222641 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,06432083 0,09217148 ! patterning of blood vessels GO:0001569 39 18 0,000 0,06432083 0,09211661 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,06432083 0,09206181 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,06432083 0,09200708 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,06432083 0,09195241 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06432083 0,09189781 ! response to retinoic acid GO:0032526 26 18 0,000 0,06432083 0,09184327 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,06432083 0,0917888 ! response to fungus GO:0009620 21 18 0,000 0,06432083 0,09173439 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,06432083 0,09168004 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,06432083 0,09162576 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,06432083 0,09157154 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,06432083 0,09151739 ! vitamin transport GO:0051180 27 18 0,000 0,06432083 0,0914633 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,06432083 0,09140928 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,06432083 0,09135532 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,06432083 0,09130142 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,06432083 0,09124759 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,06432083 0,09119382 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,06432083 0,09114011 ! nerve development GO:0021675 28 18 0,000 0,06432083 0,09108647 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,06432083 0,09103289 ! protein secretion GO:0009306 39 19 0,000 0,06777145 0,09586015 ! positive regulation of translation GO:0045727 30 19 0,000 0,06777145 0,09580383 ! negative regulation of defense response GO:0031348 25 19 0,000 0,06777145 0,09574757 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,06777145 0,09569138 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,06777145 0,09563526 ! skin development GO:0043588 36 19 0,000 0,06777145 0,0955792 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,06777145 0,09552321 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,06777145 0,09546728 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,06777145 0,09541142 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,06777145 0,09535562 ! bile acid metabolic process GO:0008206 29 19 0,000 0,06777145 0,09529989 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,06777145 0,09524423 ! cerebral cortex development GO:0021987 36 19 0,000 0,06777145 0,09518863 ! pigmentation during development GO:0048066 41 19 0,000 0,06777145 0,09513309 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,06777145 0,09507762 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,06777145 0,09502221 ! heme metabolic process GO:0042168 36 19 0,000 0,06777145 0,09496687 ! actin filament bundle formation GO:0051017 42 19 0,000 0,06777145 0,09491159 ! neuromuscular junction development GO:0007528 34 19 0,000 0,06777145 0,09485638 ! plasma membrane fusion GO:0045026 28 19 0,000 0,06777145 0,09480123 ! peptide cross-linking GO:0018149 37 19 0,000 0,06777145 0,09474614 ! protein export from nucleus GO:0006611 36 19 0,000 0,06777145 0,09469112 ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,06777145 0,09463617 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,06777145 0,09458127 ! cellular pigmentation GO:0033059 36 19 0,000 0,06777145 0,09452644 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,06777145 0,09447168 ! cell-cell junction organization GO:0045216 35 19 0,000 0,06777145 0,09441697 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,06777145 0,09436234 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,06777145 0,09430776 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,06777145 0,09425325 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,06777145 0,0941988 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,06777145 0,09414441 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,06777145 0,09409008 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,06777145 0,09403582 ! cilium assembly GO:0042384 37 19 0,000 0,06777145 0,09398162 ! peptide hormone secretion GO:0030072 31 19 0,000 0,06777145 0,09392749 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,07120947 0,09863557 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,07120947 0,09857881 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,07120947 0,09852213 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,07120947 0,09846551 ! cAMP metabolic process GO:0046058 36 20 0,000 0,07120947 0,09840895 ! response to vitamin GO:0033273 31 20 0,000 0,07120947 0,09835246 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,07120947 0,09829603 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,07120947 0,09823967 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,07120947 0,09818337 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,07120947 0,09812714 ! retinoid metabolic process GO:0001523 32 20 0,000 0,07120947 0,09807097 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,07120947 0,09801486 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,07120947 0,09795882 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,07120947 0,09790285 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,07120947 0,09784693 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,07120947 0,09779108 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,07120947 0,0977353 ! body fluid secretion GO:0007589 31 20 0,000 0,07120947 0,09767958 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,07120947 0,09762392 ! peptide secretion GO:0002790 35 20 0,000 0,07120947 0,09756833 ! stem cell differentiation GO:0048863 53 20 0,000 0,07120947 0,09751279 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,07120947 0,09745733 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,07120947 0,09740192 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,07120947 0,09734658 ! sensory perception of pain GO:0019233 30 20 0,000 0,07120947 0,0972913 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,07120947 0,09723608 ! diencephalon development GO:0021536 34 20 0,000 0,07120947 0,09718093 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,07120947 0,09712584 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,07120947 0,09707081 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,07120947 0,09701584 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,07120947 0,09696094 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,07120947 0,0969061 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,07120947 0,09685132 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,07120947 0,0967966 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,07120947 0,09674194 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,07120947 0,09668735 ! regulation of glucose import GO:0046324 29 20 0,000 0,07120947 0,09663281 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,07120947 0,09657834 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,07120947 0,09652393 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,07120947 0,09646958 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,07120947 0,09641529 ! negative regulation of translation GO:0017148 29 20 0,000 0,07120947 0,09636107 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,07120947 0,0963069 ! regulation of cell killing GO:0031341 42 21 0,000 0,07463492 0,10088293 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,07463492 0,10082628 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,07463492 0,1007697 ! hormone secretion GO:0046879 38 21 0,000 0,07463492 0,10071319 ! glycerol metabolic process GO:0006071 34 21 0,000 0,07463492 0,10065673 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,07463492 0,10060034 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,07463492 0,10054401 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,07463492 0,10048775 ! axis specification GO:0009798 38 21 0,000 0,07463492 0,10043155 ! ovarian follicle development GO:0001541 35 21 0,000 0,07463492 0,10037541 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,07463492 0,10031934 ! smooth muscle contraction GO:0006939 46 21 0,000 0,07463492 0,10026332 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,07463492 0,10020737 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,07463492 0,10015148 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,07463492 0,10009566 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,07463492 0,10003989 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,07463492 0,09998419 ! cytolysis GO:0019835 24 21 0,000 0,07463492 0,09992855 ! vasodilation GO:0042311 39 21 0,000 0,07463492 0,09987298 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,07463492 0,09981746 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,07463492 0,09976201 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,07463492 0,09970661 ! oogenesis GO:0048477 36 21 0,000 0,07463492 0,09965128 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,07463492 0,09959601 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,07463492 0,0995408 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,07463492 0,09948566 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,07463492 0,09943057 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,07463492 0,09937555 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,07463492 0,09932058 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,07463492 0,09926568 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,07463492 0,09921083 ! sperm-egg recognition GO:0035036 21 21 0,000 0,07463492 0,09915605 ! gut development GO:0048565 39 21 0,000 0,07463492 0,09910133 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,07804785 0,10357591 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,07804785 0,10351881 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,07804785 0,10346177 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,07804785 0,1034048 ! microtubule-based transport GO:0010970 54 22 0,000 0,07804785 0,10334789 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,07804785 0,10329104 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,07804785 0,10323426 ! regeneration GO:0031099 41 22 0,000 0,07804785 0,10317754 ! keratinization GO:0031424 28 22 0,000 0,07804785 0,10312088 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,07804785 0,10306428 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,07804785 0,10300774 ! sensory perception of taste GO:0050909 28 22 0,000 0,07804785 0,10295127 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,07804785 0,10289486 ! vacuolar transport GO:0007034 36 22 0,000 0,07804785 0,10283851 ! lysosome organization GO:0007040 41 22 0,000 0,07804785 0,10278222 ! central nervous system neuron development GO:0021954 46 22 0,000 0,07804785 0,10272599 ! fucose metabolic process GO:0006004 39 22 0,000 0,07804785 0,10266983 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,07804785 0,10261373 ! ureteric bud development GO:0001657 43 22 0,000 0,07804785 0,10255768 ! renal system process GO:0003014 41 22 0,000 0,07804785 0,1025017 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,07804785 0,10244578 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,07804785 0,10238992 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,07804785 0,10233412 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,07804785 0,10227839 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,07804785 0,10222271 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,07804785 0,10216709 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,07804785 0,10211154 ! protein stabilization GO:0050821 39 22 0,000 0,07804785 0,10205604 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,0814483 0,10644466 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,0814483 0,10638687 ! gluconeogenesis GO:0006094 33 23 0,000 0,0814483 0,10632914 ! viral genome replication GO:0019079 41 23 0,000 0,0814483 0,10627148 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,0814483 0,10621388 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,0814483 0,10615634 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,0814483 0,10609887 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,0814483 0,10604146 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,0814483 0,10598411 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,0814483 0,10592682 ! visual behavior GO:0007632 42 23 0,000 0,0814483 0,10586959 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,0814483 0,10581243 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,0814483 0,10575532 ! response to ethanol GO:0045471 46 23 0,000 0,0814483 0,10569828 ! peroxisome organization GO:0007031 37 23 0,000 0,0814483 0,1056413 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,0814483 0,10558438 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,0814483 0,10552752 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,0814483 0,10547073 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,0814483 0,10541399 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,0814483 0,10535732 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,0814483 0,10530071 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,0814483 0,10524415 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,0814483 0,10518766 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,0814483 0,10513123 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,0814483 0,10507486 ! fatty acid transport GO:0015908 44 23 0,000 0,0814483 0,10501855 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,0814483 0,1049623 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,0814483 0,10490611 ! hormone transport GO:0009914 40 23 0,000 0,0814483 0,10484998 ! cell-cell recognition GO:0009988 25 23 0,000 0,0814483 0,10479391 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,0814483 0,1047379 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,0814483 0,10468195 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,0814483 0,10462606 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,0814483 0,10457023 GO:0006099|tricarboxylic acid cycle, ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,08483633 0,10886197 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,08483633 0,10880395 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,08483633 0,10874598 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,08483633 0,10868807 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,08483633 0,10863023 ! vesicle docking GO:0048278 47 24 0,000 0,08483633 0,10857245 ! spinal cord development GO:0021510 47 24 0,000 0,08483633 0,10851473 ! vacuole organization GO:0007033 43 24 0,000 0,08483633 0,10845707 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,08483633 0,10839947 ! digestive system process GO:0022600 39 24 0,000 0,08483633 0,10834193 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,08483633 0,10828446 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,08483633 0,10822704 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,08483633 0,10816969 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,08483633 0,1081124 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,08483633 0,10805516 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,08483633 0,10799799 ! membrane depolarization GO:0051899 39 24 0,000 0,08483633 0,10794088 ! pallium development GO:0021543 49 24 0,000 0,08483633 0,10788383 ! pentose metabolic process GO:0019321 35 24 0,000 0,08483633 0,10782684 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,08483633 0,10776991 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,08483633 0,10771304 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,08483633 0,10765622 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,08483633 0,10759947 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,08483633 0,10754278 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,08483633 0,10748615 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,08483633 0,10742958 ! regulation of amine transport GO:0051952 40 24 0,000 0,08483633 0,10737307 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,08821197 0,11158675 ! myelination GO:0042552 45 25 0,000 0,08821197 0,11152811 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,08821197 0,11146953 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,08821197 0,11141102 ! phototransduction GO:0007602 33 25 0,000 0,08821197 0,11135257 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,08821197 0,11129418 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,08821197 0,11123585 ! receptor metabolic process GO:0043112 46 25 0,000 0,08821197 0,11117758 ! chromosome condensation GO:0030261 45 25 0,000 0,08821197 0,11111937 ! osteoblast differentiation GO:0001649 60 25 0,000 0,08821197 0,11106122 ! neural crest cell development GO:0014032 54 25 0,000 0,08821197 0,11100314 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,08821197 0,11094511 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,08821197 0,11088714 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,08821197 0,11082924 ! interaction with host GO:0051701 62 25 0,000 0,08821197 0,1107714 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,08821197 0,11071361 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,08821197 0,11065589 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,08821197 0,11059823 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,08821197 0,11054062 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,08821197 0,11048308 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,08821197 0,1104256 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,08821197 0,11036817 ! telomere organization GO:0032200 43 25 0,000 0,08821197 0,11031081 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,08821197 0,1102535 GO:0060606|tube closure, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,09157527 0,11439777 ! embryonic pattern specification GO:0009880 44 26 0,000 0,09157527 0,1143384 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,09157527 0,1142791 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,09157527 0,11421985 ! initiation of viral infection GO:0019059 57 26 0,000 0,09157527 0,11416067 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,09157527 0,11410155 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,09157527 0,11404249 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,09157527 0,1139835 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,09157527 0,11392456 ! tube lumen formation GO:0035148 50 26 0,000 0,09157527 0,11386568 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,09157527 0,11380687 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,09157527 0,11374811 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,09157527 0,11368942 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,09157527 0,11363079 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,09157527 0,11357222 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,09157527 0,1135137 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,09157527 0,11345525 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,09157527 0,11339686 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,09157527 0,11333853 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,09157527 0,11328026 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,09157527 0,11322204 ! leukocyte proliferation GO:0070661 52 26 0,000 0,09157527 0,11316389 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,09157527 0,1131058 ! neuron fate commitment GO:0048663 48 27 0,000 0,09492628 0,11718452 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,09492628 0,11712442 ! iron ion transport GO:0006826 59 27 0,000 0,09492628 0,11706439 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,09492628 0,11700442 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,09492628 0,11694451 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,09492628 0,11688466 ! fat cell differentiation GO:0045444 50 27 0,000 0,09492628 0,11682487 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,09492628 0,11676514 ! autophagy GO:0006914 41 27 0,000 0,09492628 0,11670548 ! male gonad development GO:0008584 44 27 0,000 0,09492628 0,11664587 ! primary neural tube formation GO:0014020 51 27 0,000 0,09492628 0,11658633 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,09492628 0,11652685 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,09492628 0,11646743 ! glutathione metabolic process GO:0006749 39 27 0,000 0,09492628 0,11640806 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,09492628 0,11634876 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,09492628 0,11628952 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,09492628 0,11623034 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,09492628 0,11617122 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,09826503 0,12019607 ! circadian rhythm GO:0007623 50 28 0,000 0,09826503 0,12013499 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,09826503 0,12007398 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,09826503 0,12001303 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,09826503 0,11995214 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,09826503 0,11989131 ! synaptogenesis GO:0007416 42 28 0,000 0,09826503 0,11983055 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,09826503 0,11976984 ! lipid oxidation GO:0034440 43 28 0,000 0,09826503 0,1197092 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,09826503 0,11964862 ! translational initiation GO:0006413 65 29 0,000 0,10159158 0,12363649 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,10159158 0,12357399 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,10159158 0,12351155 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,10159158 0,12344917 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,10159158 0,12338685 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,10159158 0,1233246 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,10159158 0,12326241 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,10159158 0,12320028 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,10159158 0,12313821 ! cell fate determination GO:0001709 60 29 0,000 0,10159158 0,12307621 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,10159158 0,12301427 ! detection of light stimulus GO:0009583 38 29 0,000 0,10159158 0,12295239 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,10159158 0,12289057 ! tissue homeostasis GO:0001894 48 29 0,000 0,10159158 0,12282882 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,10159158 0,12276713 ! zinc ion transport GO:0006829 45 30 0,000 0,10490597 0,12670872 ! membrane docking GO:0022406 61 30 0,000 0,10490597 0,12664514 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,10490597 0,12658163 ! regulation of innate immune response GO:0045088 51 30 0,000 0,10490597 0,12651818 ! acute-phase response GO:0006953 49 30 0,000 0,10490597 0,12645479 ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,10490597 0,12639147 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,10490597 0,12632821 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,10490597 0,12626502 ! phospholipid transport GO:0015914 51 30 0,000 0,10490597 0,12620188 ! ensheathment of neurons GO:0007272 57 30 0,000 0,10490597 0,12613882 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,10490597 0,12607581 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,10490597 0,12601287 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,10490597 0,12594998 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,10490597 0,12588717 ! eye morphogenesis GO:0048592 60 30 0,000 0,10490597 0,12582441 ! regulation of B cell activation GO:0050864 50 30 0,000 0,10490597 0,12576172 ! response to heat GO:0009408 50 30 0,000 0,10490597 0,12569909 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,10820824 0,12959136 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,10820824 0,12952688 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,10820824 0,12946247 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,10820824 0,12939813 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,10820824 0,12933385 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,10820824 0,12926963 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,10820824 0,12920548 ! ovulation cycle process GO:0022602 49 31 0,000 0,10820824 0,12914139 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,10820824 0,12907736 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,10820824 0,1290134 ! peptide transport GO:0015833 55 31 0,000 0,10820824 0,1289495 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,10820824 0,12888566 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,10820824 0,12882189 ! mesoderm formation GO:0001707 69 31 0,000 0,10820824 0,12875818 ! natural killer cell activation GO:0030101 45 31 0,000 0,10820824 0,12869453 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,10820824 0,12863095 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,10820824 0,12856742 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,10820824 0,12850397 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,10820824 0,12844057 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,10820824 0,12837724 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,11149844 0,1322155 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,11149844 0,13215037 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,11149844 0,1320853 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,11149844 0,1320203 ! cholesterol transport GO:0030301 56 32 0,000 0,11149844 0,13195536 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,11149844 0,13189049 ! spliceosome assembly GO:0000245 67 32 0,000 0,11149844 0,13182568 ! spindle organization GO:0007051 46 32 0,000 0,11149844 0,13176093 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,11149844 0,13169624 ! metanephros development GO:0001656 74 32 0,000 0,11149844 0,13163162 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,11149844 0,13156707 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,11149844 0,13150257 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,11149844 0,13143814 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,11149844 0,13137378 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,11149844 0,13130947 ! ovulation cycle GO:0042698 51 32 0,000 0,11149844 0,13124523 ! peripheral nervous system development GO:0007422 64 32 0,000 0,11149844 0,13118105 ! BMP signaling pathway GO:0030509 64 32 0,000 0,11149844 0,13111694 ! hindbrain development GO:0030902 61 32 0,000 0,11149844 0,13105288 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,11149844 0,13098889 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,11149844 0,13092496 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,11149844 0,1308611 ! gene silencing GO:0016458 65 32 0,000 0,11149844 0,13079729 ! post-embryonic development GO:0009791 69 33 0,000 0,11477661 0,13457725 ! protein targeting to membrane GO:0006612 68 33 0,000 0,11477661 0,1345117 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,11477661 0,13444621 ! ceramide metabolic process GO:0006672 64 33 0,000 0,11477661 0,13438079 ! formation of primary germ layer GO:0001704 72 33 0,000 0,11477661 0,13431543 ! cell fate specification GO:0001708 52 33 0,000 0,11477661 0,13425013 ! sterol transport GO:0015918 57 33 0,000 0,11477661 0,1341849 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,11477661 0,13411973 ! adult locomotory behavior GO:0008344 59 33 0,000 0,11477661 0,13405462 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,11477661 0,13398958 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,11477661 0,1339246 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,11804279 0,13766891 ! glial cell differentiation GO:0010001 63 34 0,000 0,11804279 0,13760221 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,11804279 0,13753557 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,11804279 0,137469 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,11804279 0,13740249 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,11804279 0,13733605 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,11804279 0,13726967 ! mismatch repair GO:0006298 46 34 0,000 0,11804279 0,13720336 ! spermatid development GO:0007286 63 34 0,000 0,11804279 0,13713711 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,11804279 0,13707092 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,11804279 0,1370048 ! regulation of muscle development GO:0048634 70 35 0,000 0,12129703 0,14071391 ! negative regulation of secretion GO:0051048 63 35 0,000 0,12129703 0,1406461 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,12129703 0,14057835 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,12129703 0,14051066 ! odontogenesis GO:0042476 66 35 0,000 0,12129703 0,14044305 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,12129703 0,14037549 ! female gonad development GO:0008585 58 35 0,000 0,12129703 0,140308 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,12129703 0,14024058 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,12129703 0,14017322 ! cytokine production GO:0001816 59 35 0,000 0,12129703 0,14010593 ! neural tube formation GO:0001841 67 35 0,000 0,12129703 0,1400387 ! vesicle localization GO:0051648 64 35 0,000 0,12129703 0,13997153 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,12453937 0,14364416 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,12453937 0,14357533 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,12453937 0,14350657 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,12453937 0,14343787 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,12453937 0,14336924 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,12453937 0,14330068 ! regulation of proteolysis GO:0030162 72 36 0,000 0,12453937 0,14323218 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,12453937 0,14316374 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,12453937 0,14309538 ! aerobic respiration GO:0009060 55 36 0,000 0,12453937 0,14302707 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,12453937 0,14295883 ! embryonic organ development GO:0048568 57 36 0,000 0,12453937 0,14289066 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,12453937 0,14282255 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,12453937 0,14275451 ! meiosis I GO:0007127 65 37 0,000 0,12776985 0,14638774 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,12776985 0,14631807 ! sister chromatid segregation GO:0000819 58 37 0,000 0,12776985 0,14624846 ! organic anion transport GO:0015711 68 37 0,000 0,12776985 0,14617891 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,12776985 0,14610944 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,12776985 0,14604003 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,12776985 0,14597068 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,12776985 0,1459014 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,12776985 0,14583219 ! glycogen metabolic process GO:0005977 61 37 0,000 0,12776985 0,14576304 ! pigment metabolic process GO:0042440 80 37 0,000 0,12776985 0,14569396 ! spermatid differentiation GO:0048515 66 37 0,000 0,12776985 0,14562494 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,13098852 0,14922271 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,13098852 0,14915209 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,13098852 0,14908154 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,13098852 0,14901105 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,13098852 0,14894063 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,13098852 0,14887028 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,13098852 0,14879999 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,13098852 0,14872977 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,13098852 0,14865961 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,13098852 0,14858952 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,13098852 0,1485195 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,13098852 0,14844954 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 0,000 0,13098852 0,14837965 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 0,000 0,13419542 0,15194079 ! learning GO:0007612 77 39 0,000 0,13419542 0,15186932 ! organic ether metabolic process GO:0018904 55 39 0,000 0,13419542 0,15179792 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,13419542 0,15172658 ! ion transmembrane transport GO:0034220 66 39 0,000 0,13419542 0,15165532 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,13419542 0,15158412 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,13419542 0,15151298 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,13419542 0,15144192 ! RNA modification GO:0009451 57 39 0,000 0,13419542 0,15137092 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,13419542 0,15129999 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,13739058 0,15482986 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,13739058 0,15475737 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,13739058 0,15468495 ! feeding behavior GO:0007631 59 40 0,000 0,13739058 0,1546126 ! negative regulation of binding GO:0051100 72 40 0,000 0,13739058 0,15454032 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,13739058 0,15446811 ! maintenance of protein location GO:0045185 91 40 0,000 0,13739058 0,15439596 ! cytokinesis GO:0000910 72 40 0,000 0,13739058 0,15432388 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,14057407 0,15782604 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,14057407 0,15775243 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,14057407 0,15767889 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,14057407 0,15760541 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,14057407 0,157532 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,14057407 0,15745866 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,14057407 0,15738539 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,14057407 0,15731219 ! female gamete generation GO:0007292 61 41 0,000 0,14057407 0,15723906 ! polyol metabolic process GO:0019751 66 41 0,000 0,14057407 0,15716599 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,14057407 0,15709299 ! regulation of tube size GO:0035150 71 42 0,000 0,14374591 0,16056298 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,14374591 0,16048847 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,14374591 0,16041403 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,14374591 0,16033966 ! neuron migration GO:0001764 79 42 0,000 0,14374591 0,16026536 ! regulation of protein secretion GO:0050708 71 42 0,000 0,14374591 0,16019113 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,14374591 0,16011697 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,14690615 0,1635614 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,14690615 0,16348575 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,14690615 0,16341017 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,14690615 0,16333466 ! glucose transport GO:0015758 65 43 0,000 0,14690615 0,16325921 ! neural tube development GO:0021915 77 43 0,000 0,14690615 0,16318384 ! phagocytosis GO:0006909 90 43 0,000 0,14690615 0,16310853 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,14690615 0,1630333 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,15005483 0,16645086 ! hexose transport GO:0008645 67 44 0,000 0,15005483 0,16637416 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,15005483 0,16629752 ! male sex differentiation GO:0046661 76 44 0,000 0,15005483 0,16622096 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,15005483 0,16614446 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,15005483 0,16606804 ! developmental growth GO:0048589 82 44 0,000 0,15005483 0,16599169 ! maintenance of location in cell GO:0051651 97 44 0,000 0,15005483 0,1659154 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,15319199 0,16930635 ! glycolysis GO:0006096 65 45 0,000 0,15319199 0,16922862 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,15319199 0,16915096 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,15319199 0,16907336 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,15319199 0,16899584 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,15319199 0,16891839 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,15319199 0,16884101 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,15319199 0,16876371 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,15319199 0,16868647 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,15631768 0,17204956 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,15631768 0,17197089 ! positive regulation of defense response GO:0031349 76 47 0,000 0,15943193 0,17531683 ! response to calcium ion GO:0051592 81 47 0,000 0,15943193 0,17523674 ! endosome transport GO:0016197 108 47 0,000 0,15943193 0,17515673 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,15943193 0,17507678 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,15943193 0,17499691 ! Notch signaling pathway GO:0007219 96 48 0,000 0,1625348 0,17832135 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,1625348 0,17824007 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,1625348 0,17815887 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,1625348 0,17807774 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,1625348 0,17799669 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,1625348 0,17791571 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,1625348 0,1778348 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,16562631 0,18113495 ! regulation of action potential GO:0001508 95 49 0,000 0,16562631 0,18105266 ! regulation of ion transport GO:0043269 77 49 0,000 0,16562631 0,18097043 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,16562631 0,18088829 ! peptide metabolic process GO:0006518 76 49 0,000 0,16562631 0,18080621 ! response to temperature stimulus GO:0009266 76 49 0,000 0,16562631 0,18072422 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,16562631 0,18064229 ! endocrine system development GO:0035270 104 49 0,000 0,16562631 0,18056044 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,16562631 0,18047867 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,16562631 0,18039696 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,16562631 0,18031534 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,16870651 0,18358564 ! neuromuscular process GO:0050905 99 50 0,000 0,16870651 0,18350265 ! inner ear development GO:0048839 79 50 0,000 0,16870651 0,18341973 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,16870651 0,18333688 ! viral infectious cycle GO:0019058 99 51 0,000 0,17177544 0,18658768 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,17177544 0,18650348 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,17177544 0,18641935 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,17177544 0,18633531 ! excretion GO:0007588 83 51 0,000 0,17177544 0,18625133 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,17177544 0,18616744 ! chromatin remodeling GO:0006338 109 51 0,000 0,17177544 0,18608361 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,17177544 0,18599987 ! vesicle organization GO:0016050 107 51 0,000 0,17177544 0,1859162 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,17177544 0,1858326 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,17177544 0,18574908 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,17483314 0,1889706 ! membrane fusion GO:0006944 110 52 0,000 0,17483314 0,18888574 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,17483314 0,18880096 ! amino acid activation GO:0043038 92 52 0,000 0,17483314 0,18871626 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 0,000 0,17483314 0,18863163 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,17787966 0,19183257 ! regulation of translational initiation GO:0006446 82 53 0,000 0,17787966 0,19174662 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,17787966 0,19166075 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,17787966 0,19157496 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,17787966 0,19148925 ! cell maturation GO:0048469 100 53 0,000 0,17787966 0,19140361 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,17787966 0,19131804 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,18091503 0,19449578 ! cell recognition GO:0008037 85 54 0,000 0,18091503 0,19440892 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,18091503 0,19432213 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,18091503 0,19423541 ! chloride transport GO:0006821 90 55 0,000 0,18393929 0,19739426 ! glucose catabolic process GO:0006007 82 55 0,000 0,18393929 0,19730626 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,18393929 0,19721833 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,18393929 0,19713049 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,18393929 0,19704272 ! gastrulation GO:0007369 112 55 0,000 0,18393929 0,19695502 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,18393929 0,19686741 ! RNA elongation GO:0006354 79 55 0,000 0,18393929 0,19677988 ! regulation of actin filament length GO:0030832 105 56 0,000 0,18695249 0,19991453 ! sensory perception of smell GO:0007608 80 56 0,000 0,18695249 0,19982572 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,18695249 0,19973699 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,18695249 0,19964833 ! proton transport GO:0015992 94 56 0,000 0,18695249 0,19955976 ! muscle fiber development GO:0048747 112 57 0,000 0,18995466 0,20267446 ! maintenance of location GO:0051235 118 57 0,000 0,18995466 0,20258463 ! hydrogen transport GO:0006818 97 58 0,000 0,19294585 0,20568352 ! regulation of endocytosis GO:0030100 91 58 0,000 0,19294585 0,20559243 ! adult behavior GO:0030534 99 58 0,000 0,19294585 0,20550142 ! positive regulation of secretion GO:0051047 95 59 0,000 0,19592609 0,20858326 ! regulation of cellular component size GO:0032535 109 59 0,000 0,19592609 0,20849101 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,19592609 0,20839884 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,19592609 0,20830675 ! establishment of organelle localization GO:0051656 109 59 0,000 0,19592609 0,20821474 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,19889542 0,21127699 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,19889542 0,21118375 ! camera-type eye development GO:0043010 116 60 0,000 0,19889542 0,2110906 ! kidney development GO:0001822 122 60 0,000 0,19889542 0,21099752 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,20185389 0,21404163 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,20185389 0,21394733 ! mesoderm development GO:0007498 119 61 0,000 0,20185389 0,21385313 ! tRNA processing GO:0008033 89 61 0,000 0,20185389 0,213759 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,20185389 0,21366496 ! viral reproductive process GO:0022415 126 62 0,000 0,20480152 0,21668974 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,20480152 0,21659449 ! gonad development GO:0008406 98 62 0,000 0,20480152 0,21649933 ! regulation of mitosis GO:0007088 105 63 0,000 0,20773837 0,21950748 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,20773837 0,21941112 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,20773837 0,21931484 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,20773837 0,21921865 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,20773837 0,21912255 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,21066448 0,22211162 ! cell redox homeostasis GO:0045454 102 64 0,000 0,21066448 0,22201434 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,21066448 0,22191713 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,21066448 0,22182001 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,21066448 0,22172298 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,21357987 0,22469312 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,21357987 0,22459491 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,21357987 0,22449679 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,21357987 0,22439876 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,21648459 0,22735134 ! actin filament organization GO:0007015 148 66 0,000 0,21648459 0,22725214 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,21648459 0,22715304 ! secondary metabolic process GO:0019748 116 66 0,000 0,21648459 0,22705402 ! developmental maturation GO:0021700 116 66 0,000 0,21648459 0,22695508 ! cell projection assembly GO:0030031 120 66 0,000 0,21648459 0,22685623 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,21937867 0,22978889 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,21937867 0,2296889 ! chromosome segregation GO:0007059 113 67 0,000 0,21937867 0,22958899 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,21937867 0,22948917 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,21937867 0,22938943 ! hexose catabolic process GO:0019320 104 67 0,000 0,21937867 0,22928979 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,21937867 0,22919022 ! amino acid transport GO:0006865 125 68 0,000 0,22226217 0,2321019 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,22226217 0,2320012 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,22226217 0,23190059 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,22226217 0,23180007 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,22226217 0,23169964 ! viral reproduction GO:0016032 134 68 0,000 0,22226217 0,23159929 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,22226217 0,23149904 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,2251351 0,2343899 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,2251351 0,23428852 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,2251351 0,23418723 ! antigen processing and presentation GO:0019882 104 69 0,000 0,2251351 0,23408602 ! appendage morphogenesis GO:0035107 135 70 0,000 0,22799752 0,23695985 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,23084946 0,2398203 ! appendage development GO:0048736 136 71 0,000 0,23084946 0,23971679 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,23084946 0,23961338 ! regulation of immune effector process GO:0002697 137 71 0,000 0,23084946 0,23951005 ! acute inflammatory response GO:0002526 113 72 0,000 0,23369096 0,24235365 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,23369096 0,24224923 ! carbohydrate transport GO:0008643 110 72 0,000 0,23369096 0,2421449 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,23369096 0,24204066 ! learning or memory GO:0007611 147 73 0,000 0,23652206 0,2448675 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,23652206 0,24476219 ! fertilization GO:0009566 90 73 0,000 0,23652206 0,24465696 ! transition metal ion transport GO:0000041 126 74 0,000 0,23934279 0,24746831 ! neurotransmitter transport GO:0006836 123 74 0,000 0,23934279 0,24736201 ! meiosis GO:0007126 121 74 0,000 0,23934279 0,2472558 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,23934279 0,24714968 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,23934279 0,24704366 ! organelle localization GO:0051640 136 74 0,000 0,23934279 0,24693772 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,2421532 0,24973021 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,2421532 0,24962322 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,2421532 0,24951631 ! meiotic cell cycle GO:0051321 122 75 0,000 0,2421532 0,2494095 ! rhythmic process GO:0048511 128 75 0,000 0,2421532 0,24930278 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,24495331 0,2520777 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,24495331 0,25196993 ! defense response to bacterium GO:0042742 89 76 0,000 0,24495331 0,25186225 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,24495331 0,25175466 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,24495331 0,25164717 ! regulation of catabolic process GO:0009894 161 76 0,000 0,24495331 0,25153976 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,24774317 0,2542961 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,24774317 0,25418766 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,25052281 0,25693005 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,25052281 0,25682057 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,25329228 0,25954907 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,25329228 0,25943858 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,2560516 0,26215326 ! response to metal ion GO:0010038 140 80 0,000 0,2560516 0,26204175 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,2560516 0,26193034 ! inorganic anion transport GO:0015698 138 80 0,000 0,2560516 0,26181902 ! digestion GO:0007586 112 81 0,000 0,25880082 0,26451775 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,25880082 0,26440542 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,25880082 0,2642932 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,26153997 0,26697716 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,26153997 0,26686394 ! response to nutrient GO:0007584 125 82 0,000 0,26153997 0,26675081 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,26153997 0,26663778 ! regulation of lyase activity GO:0051339 160 83 0,000 0,26426909 0,26930598 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,26698821 0,27196174 ! negative regulation of transport GO:0051051 153 84 0,000 0,26698821 0,27184665 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,26698821 0,27173166 ! response to unfolded protein GO:0006986 131 85 0,000 0,26969737 0,27437289 ! nucleosome assembly GO:0006334 122 85 0,000 0,26969737 0,27425692 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,26969737 0,27414106 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 0,000 0,27239662 0,27676784 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,27239662 0,27665102 ! chromatin assembly GO:0031497 124 86 0,000 0,27239662 0,27653429 ! tube morphogenesis GO:0035239 176 86 0,000 0,27239662 0,27641765 ! alcohol catabolic process GO:0046164 130 86 0,000 0,27239662 0,27630112 ! amine transport GO:0015837 155 86 0,000 0,27239662 0,27618468 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,27508597 0,27879395 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,27508597 0,27867656 ! cellular respiration GO:0045333 135 88 0,000 0,27776547 0,28127261 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,27776547 0,28115428 ! regulation of neurological system process GO:0031644 148 88 0,000 0,27776547 0,28103605 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,27776547 0,28091792 ! cellular defense response GO:0006968 114 89 0,000 0,28043516 0,28349874 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,28309507 0,2860675 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,28309507 0,28594741 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,28309507 0,28582741 ! sterol metabolic process GO:0016125 152 91 0,000 0,28574523 0,28838214 ! response to protein stimulus GO:0051789 149 91 0,000 0,28574523 0,28826122 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,28574523 0,28814041 ! regulation of defense response GO:0031347 149 92 0,000 0,28838568 0,29068117 ! nucleosome organization GO:0034728 138 92 0,000 0,28838568 0,29055944 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,28838568 0,29043782 ! vitamin metabolic process GO:0006766 139 92 0,000 0,28838568 0,2903163 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,29101646 0,29284216 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,29101646 0,29271974 ! regulation of membrane potential GO:0042391 164 93 0,000 0,29101646 0,29259741 ! female pregnancy GO:0007565 164 94 0,000 0,29363761 0,29510947 ! regulation of T cell activation GO:0050863 158 94 0,000 0,29363761 0,29498625 ! forebrain development GO:0030900 188 95 0,000 0,29624914 0,29748558 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,29624914 0,29736147 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,29885111 0,29984812 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,30144355 0,30232313 ! protein ubiquitination GO:0016567 217 97 0,000 0,30144355 0,30219716 ! hormone metabolic process GO:0042445 157 97 0,000 0,30144355 0,3020713 ! response to virus GO:0009615 160 98 0,000 0,30402649 0,30453278 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,30402649 0,30440605 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,30402649 0,30427942 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,30659996 0,30672744 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,30659996 0,30659996