pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/967-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! protein sumoylation GO:0016925 17 10 5,000 6,639E-12 1,622E-08 ! positive regulation of protein complex assembly GO:0031334 34 18 5,000 5,65E-10 6,901E-07 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 5,000 5,916E-07 4,818E-04 ! negative regulation of transcription regulator activity GO:0090048 57 30 4,000 7,338E-07 4,482E-04 GO:0043433|negative regulation of transcription factor activity, ! regulation of protein complex assembly GO:0043254 132 63 5,000 1,67E-06 8,159E-04 ! negative regulation of DNA binding GO:0043392 67 36 4,000 1,888E-06 7,687E-04 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 3,000 2,319E-06 8,094E-04 ! negative regulation of binding GO:0051100 71 39 4,000 2,844E-06 8,684E-04 ! positive regulation of cytokine production during immune response GO:0002720 11 6 2,000 3,625E-06 9,84E-04 ! regulation of transcription factor activity GO:0051090 137 75 5,000 4,675E-06 1,142E-03 GO:0090046|regulation of transcription regulator activity, ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 2,000 1,006E-05 2,235E-03 ! regulation of DNA binding GO:0051101 167 89 5,000 1,263E-05 2,571E-03 ! retinal ganglion cell axon guidance GO:0031290 14 9 2,000 1,503E-05 2,825E-03 ! autophagic vacuole formation GO:0000045 17 10 2,000 2,139E-05 3,732E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 3,000 2,193E-05 3,572E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 2,000 2,928E-05 4,471E-03 ! macroautophagy GO:0016236 19 11 2,000 2,928E-05 4,208E-03 ! positive regulation of T cell mediated immunity GO:0002711 26 11 2,000 2,928E-05 3,974E-03 ! cranial nerve development GO:0021545 23 12 2,000 3,888E-05 4,999E-03 ! regulation of cytokine production during immune response GO:0002718 25 13 2,000 5,033E-05 6,147E-03 ! ribosomal large subunit biogenesis GO:0042273 13 13 2,000 5,033E-05 5,855E-03 ! androgen receptor signaling pathway GO:0030521 81 37 3,000 5,885E-05 6,535E-03 ! retina development in camera-type eye GO:0060041 28 14 2,000 6,378E-05 6,775E-03 ! ribosome assembly GO:0042255 18 14 2,000 6,378E-05 6,493E-03 ! positive regulation of protein polymerization GO:0032273 27 14 2,000 6,378E-05 6,233E-03 ! G1/S transition checkpoint GO:0031575 37 15 2,000 7,939E-05 7,46E-03 ! regulation of T cell mediated immunity GO:0002709 36 15 2,000 7,939E-05 7,184E-03 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 7,939E-05 6,927E-03 ! nerve development GO:0021675 34 18 2,000 1,406E-04 0,01184391 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 2,000 1,663E-04 0,01353867 ! regulation of interleukin-2 production GO:0032663 39 20 2,000 1,948E-04 0,01534926 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 2,263E-04 0,01727498 ! regulation of T cell activation GO:0050863 175 96 4,000 2,32E-04 0,01717378 ! vesicle organization GO:0016050 127 53 3,000 2,43E-04 0,0174574 ! regulation of protein localization GO:0032880 188 97 4,000 2,435E-04 0,01699401 ! cellular response to starvation GO:0009267 37 22 2,000 2,609E-04 0,01770541 ! positive regulation of adaptive immune response GO:0002821 42 22 2,000 2,609E-04 0,01722688 ! negative regulation of cell motion GO:0051271 142 55 3,000 2,805E-04 0,01803119 ! microvillus organization GO:0032528 8 5 1,000 3,209E-04 0,02010327 GO:0030033|microvillus assembly, ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 1,000 3,209E-04 0,01960069 ! positive regulation of transporter activity GO:0032411 8 5 1,000 3,209E-04 0,01912262 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 3,209E-04 0,01866732 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 1,000 3,209E-04 0,0182332 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! positive regulation of vasoconstriction GO:0045907 10 5 1,000 3,209E-04 0,01781881 ! coenzyme A biosynthetic process GO:0015937 7 5 1,000 3,209E-04 0,01742283 ! regulation of sensory perception GO:0051931 8 5 1,000 3,209E-04 0,01704408 GO:0051930|regulation of sensory perception of pain, ! protein insertion into membrane GO:0051205 17 5 1,000 3,209E-04 0,01668144 ! stem cell division GO:0017145 11 5 1,000 3,209E-04 0,01633391 GO:0048103|somatic stem cell division, ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 3,22E-04 0,01605203 ! chloride transport GO:0006821 102 57 3,000 3,22E-04 0,01573099 ! positive regulation of cytoskeleton organization GO:0051495 52 24 2,000 3,4E-04 0,01628821 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 2,000 3,4E-04 0,01597497 GO:0002708|positive regulation of lymphocyte mediated immunity, ! positive regulation of actin filament polymerization GO:0030838 11 6 1,000 4,796E-04 0,02210591 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 1,000 4,796E-04 0,02169655 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 1,000 4,796E-04 0,02130206 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 4,796E-04 0,02092167 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 4,796E-04 0,02055462 ! purine base biosynthetic process GO:0009113 17 6 1,000 4,796E-04 0,02020023 ! myeloid dendritic cell activation GO:0001773 10 6 1,000 4,796E-04 0,01985786 GO:0043011|myeloid dendritic cell differentiation, ! negative regulation of B cell activation GO:0050869 14 6 1,000 4,796E-04 0,01952689 ! response to starvation GO:0042594 47 27 2,000 4,852E-04 0,01943348 ! cellular response to nutrient levels GO:0031669 45 27 2,000 4,852E-04 0,01912004 ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 5,02E-04 0,01946659 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 5,412E-04 0,02065824 ! steroid hormone receptor signaling pathway GO:0030518 146 66 3,000 5,644E-04 0,02121258 ! autophagy GO:0006914 47 29 2,000 6,011E-04 0,02224996 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 2,000 6,011E-04 0,02191787 ! positive regulation of T cell activation GO:0050870 124 68 3,000 6,321E-04 0,02270927 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 6,68E-04 0,02365214 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 1,000 6,689E-04 0,02334408 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 6,689E-04 0,02301529 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 6,689E-04 0,02269564 ! establishment of tissue polarity GO:0007164 8 7 1,000 6,689E-04 0,02238474 ! vesicle fusion GO:0006906 20 7 1,000 6,689E-04 0,02208224 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 1,000 6,689E-04 0,02178781 ! coenzyme A metabolic process GO:0015936 12 7 1,000 6,689E-04 0,02150113 ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 1,000 6,689E-04 0,0212219 ! protein modification by small protein removal GO:0070646 19 7 1,000 6,689E-04 0,02094982 ! positive regulation of microtubule polymerization GO:0031116 15 7 1,000 6,689E-04 0,02068463 ! negative regulation of kinase activity GO:0033673 145 70 3,000 7,054E-04 0,02154048 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 7,333E-04 0,02211574 ! positive regulation of immune effector process GO:0002699 78 31 2,000 7,333E-04 0,02184603 ! cell cycle checkpoint GO:0000075 145 71 3,000 7,442E-04 0,02190399 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 3,000 7,442E-04 0,02164322 ! negative regulation of transferase activity GO:0051348 155 74 3,000 8,696E-04 0,02499379 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 8,885E-04 0,02523937 ! T-helper 1 type immune response GO:0042088 12 8 1,000 8,885E-04 0,02494926 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 1,000 8,885E-04 0,02466574 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 8,885E-04 0,0243886 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 8,885E-04 0,02411762 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 8,885E-04 0,02385259 ! gas homeostasis GO:0033483 14 8 1,000 8,885E-04 0,02359332 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 1,000 8,885E-04 0,02333963 ! regulation of microtubule polymerization GO:0031113 17 8 1,000 8,885E-04 0,02309133 ! cell fate specification GO:0001708 56 34 2,000 9,64E-04 0,02478887 ! positive regulation of lymphocyte activation GO:0051251 142 78 3,000 1,059E-03 0,02695202 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 3,000 1,111E-03 0,02797252 ! protein oligomerization GO:0051259 149 79 3,000 1,111E-03 0,02768709 ! 'de novo' posttranslational protein folding GO:0051084 15 9 1,000 1,138E-03 0,02808343 ! regulation of epithelial cell differentiation GO:0030856 18 9 1,000 1,138E-03 0,0278026 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,138E-03 0,02752732 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 1,000 1,138E-03 0,02725745 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 1,138E-03 0,02699281 ! purine base metabolic process GO:0006144 25 9 1,000 1,138E-03 0,02673327 ! activation of protein kinase activity GO:0032147 170 80 3,000 1,164E-03 0,02708107 ! response to hypoxia GO:0001666 178 81 3,000 1,219E-03 0,02809437 ! response to oxygen levels GO:0070482 183 83 3,000 1,335E-03 0,03046942 ! inorganic anion transport GO:0015698 156 83 3,000 1,335E-03 0,03018729 ! regulation of ligase activity GO:0051340 147 84 3,000 1,395E-03 0,03126709 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 1,417E-03 0,03147512 ! nucleobase biosynthetic process GO:0046112 26 10 1,000 1,417E-03 0,03119156 ! induction of an organ GO:0001759 17 10 1,000 1,417E-03 0,03091307 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,417E-03 0,0306395 ! mitotic cell cycle checkpoint GO:0007093 76 39 2,000 1,442E-03 0,03089434 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 2,000 1,442E-03 0,03062569 ! positive regulation of cell activation GO:0050867 161 86 3,000 1,522E-03 0,03205008 GO:0002696|positive regulation of leukocyte activation, ! mesenchymal cell development GO:0014031 94 41 2,000 1,668E-03 0,03481917 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! thyroid gland development GO:0030878 26 11 1,000 1,726E-03 0,03572677 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 1,726E-03 0,03542655 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 1,726E-03 0,03513133 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,726E-03 0,03484098 ! nitric oxide metabolic process GO:0046209 17 11 1,000 1,726E-03 0,0345554 GO:0006809|nitric oxide biosynthetic process, ! apical protein localization GO:0045176 18 11 1,000 1,726E-03 0,03427446 ! T cell receptor signaling pathway GO:0050852 29 11 1,000 1,726E-03 0,03399806 ! regulation of leukocyte mediated immunity GO:0002703 84 42 2,000 1,788E-03 0,03495109 ! response to unfolded protein GO:0006986 139 90 3,000 1,799E-03 0,03488107 ! regulation of T cell proliferation GO:0042129 80 43 2,000 1,914E-03 0,03682627 ! regulation of B cell proliferation GO:0030888 22 12 1,000 2,063E-03 0,03937434 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 1,000 2,063E-03 0,03906911 ! regulation of interleukin-12 production GO:0032655 19 12 1,000 2,063E-03 0,03876858 ! histone acetylation GO:0016573 27 12 1,000 2,063E-03 0,03847264 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,063E-03 0,03818118 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 2,063E-03 0,0378941 GO:0042130|negative regulation of T cell proliferation, ! developmental induction GO:0031128 22 12 1,000 2,063E-03 0,03761131 GO:0045168|cell-cell signaling involved in cell fate specification, ! lamellipodium assembly GO:0030032 24 12 1,000 2,063E-03 0,03733271 ! localization within membrane GO:0051668 26 12 1,000 2,063E-03 0,0370582 ! receptor-mediated endocytosis GO:0006898 98 45 2,000 2,183E-03 0,03892593 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 2,000 2,183E-03 0,03864386 ! response to protein stimulus GO:0051789 158 96 3,000 2,278E-03 0,04003112 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 2,325E-03 0,04057931 ! negative regulation of cell migration GO:0030336 122 46 2,000 2,325E-03 0,04029151 ! 'de novo' protein folding GO:0006458 26 13 1,000 2,429E-03 0,0417881 ! organelle fusion GO:0048284 36 13 1,000 2,429E-03 0,04149587 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 1,000 2,429E-03 0,04120771 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! asymmetric protein localization GO:0008105 24 13 1,000 2,429E-03 0,04092352 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 2,429E-03 0,04064322 ! histone methylation GO:0016571 29 13 1,000 2,429E-03 0,04036673 ! gland morphogenesis GO:0022612 31 13 1,000 2,429E-03 0,04009398 ! positive regulation of homeostatic process GO:0032846 23 13 1,000 2,429E-03 0,0398249 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 1,000 2,429E-03 0,0395594 ! regulation of adaptive immune response GO:0002819 92 48 2,000 2,628E-03 0,04251074 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 2,787E-03 0,04479769 ! protein homooligomerization GO:0051260 84 49 2,000 2,787E-03 0,04450489 ! hair follicle morphogenesis GO:0031069 27 14 1,000 2,823E-03 0,04478522 ! lipid localization GO:0010876 32 14 1,000 2,823E-03 0,04449629 GO:0019915|lipid storage, ! regulation of calcium-mediated signaling GO:0050848 29 14 1,000 2,823E-03 0,04421105 ! positive regulation of cytokine production GO:0001819 94 50 2,000 2,953E-03 0,04594703 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 3,245E-03 0,05017817 ! regulation of vasodilation GO:0042312 27 15 1,000 3,245E-03 0,04986258 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 3,245E-03 0,04955094 ! positive regulation of calcium ion transport GO:0051928 21 15 1,000 3,245E-03 0,04924317 ! histone modification GO:0016570 104 52 2,000 3,302E-03 0,04979106 ! ribonucleoprotein complex assembly GO:0022618 104 52 2,000 3,302E-03 0,04948559 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 3,485E-03 0,05191773 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! covalent chromatin modification GO:0016569 115 54 2,000 3,675E-03 0,05441103 ! positive regulation of ion transport GO:0043270 23 16 1,000 3,695E-03 0,05437822 ! startle response GO:0001964 28 16 1,000 3,695E-03 0,0540526 ! regulation of transmembrane transporter activity GO:0022898 27 16 1,000 3,695E-03 0,05373086 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! protein polyubiquitination GO:0000209 41 16 1,000 3,695E-03 0,05341292 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 1,000 3,695E-03 0,05309873 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 3,695E-03 0,05278821 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of protein polymerization GO:0032271 117 55 2,000 3,871E-03 0,05497815 ! signal complex assembly GO:0007172 47 17 1,000 4,172E-03 0,05891347 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 4,172E-03 0,05857489 ! nucleobase metabolic process GO:0009112 43 17 1,000 4,172E-03 0,05824017 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 4,172E-03 0,05790926 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 1,000 4,172E-03 0,05758209 ! positive regulation of organelle organization GO:0010638 108 58 2,000 4,496E-03 0,06170567 ! epidermis morphogenesis GO:0048730 43 18 1,000 4,676E-03 0,0638162 ! glutamine metabolic process GO:0006541 29 18 1,000 4,676E-03 0,06346167 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 4,676E-03 0,06311105 ! regulation of immunoglobulin production GO:0002637 49 18 1,000 4,676E-03 0,06276429 ! cytokine-mediated signaling pathway GO:0019221 112 61 2,000 5,179E-03 0,06913671 ! camera-type eye development GO:0043010 126 61 2,000 5,179E-03 0,06876097 ! response to lipopolysaccharide GO:0032496 34 19 1,000 5,206E-03 0,06875249 ! cellular pigmentation GO:0033059 37 19 1,000 5,206E-03 0,06838285 ! mesoderm development GO:0007498 128 63 2,000 5,667E-03 0,07403403 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 5,763E-03 0,07489142 ! protein amino acid acetylation GO:0006473 41 20 1,000 5,763E-03 0,07449517 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 5,763E-03 0,07410309 ! actin filament bundle formation GO:0051017 47 20 1,000 5,763E-03 0,07371511 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 5,763E-03 0,07333118 ! negative regulation of T cell activation GO:0050868 41 20 1,000 5,763E-03 0,07295123 ! positive regulation of cell motion GO:0051272 157 65 2,000 6,182E-03 0,07784476 ! lipid phosphorylation GO:0046834 43 21 1,000 6,346E-03 0,07950492 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 6,346E-03 0,07909928 ! regulation of vasoconstriction GO:0019229 40 21 1,000 6,346E-03 0,07869776 ! ribosomal small subunit biogenesis GO:0042274 25 21 1,000 6,346E-03 0,0783003 ! inactivation of MAPK activity GO:0000188 45 22 1,000 6,955E-03 0,08537721 ! apoptotic nuclear changes GO:0030262 34 22 1,000 6,955E-03 0,08495033 ! negative regulation of ligase activity GO:0051352 116 68 2,000 7,005E-03 0,08513577 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 2,000 7,005E-03 0,08471431 ! cell projection assembly GO:0030031 138 68 2,000 7,005E-03 0,084297 ! lung development GO:0030324 165 69 2,000 7,293E-03 0,08733304 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 2,000 7,293E-03 0,08690702 ! urogenital system development GO:0001655 149 69 2,000 7,293E-03 0,08648514 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 7,588E-03 0,0895587 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 7,588E-03 0,08912813 ! regulation of interleukin-6 production GO:0032675 31 23 1,000 7,588E-03 0,08870168 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 7,588E-03 0,08827929 ! response to molecule of bacterial origin GO:0002237 40 23 1,000 7,588E-03 0,0878609 ! respiratory tube development GO:0030323 171 72 2,000 8,198E-03 0,09447532 ! actin filament organization GO:0007015 167 72 2,000 8,198E-03 0,09403178 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 2,000 8,198E-03 0,09359238 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 2,000 8,198E-03 0,09315706 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 8,247E-03 0,09327993 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 8,247E-03 0,09285006 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 1,000 8,247E-03 0,09242415 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! purine ribonucleoside metabolic process GO:0046128 38 24 1,000 8,247E-03 0,09200212 GO:0042278|purine nucleoside metabolic process, ! sex determination GO:0007530 48 24 1,000 8,247E-03 0,09158393 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 8,247E-03 0,09116952 ! membrane depolarization GO:0051899 45 24 1,000 8,247E-03 0,09075885 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 8,247E-03 0,09035186 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 8,247E-03 0,0899485 ! regulation of immune effector process GO:0002697 156 73 2,000 8,514E-03 0,09244726 ! respiratory system development GO:0060541 175 74 2,000 8,837E-03 0,09552994 ! myeloid leukocyte differentiation GO:0002573 46 25 1,000 8,931E-03 0,0961179 ! regulation of transmembrane transport GO:0034762 39 25 1,000 8,931E-03 0,09569633 ! vasculogenesis GO:0001570 49 25 1,000 8,931E-03 0,09527845 ! eye development GO:0001654 155 75 2,000 9,168E-03 0,09737499 ! axon guidance GO:0007411 162 75 2,000 9,168E-03 0,09695346 ! molting cycle process GO:0022404 52 26 1,000 9,639E-03 0,10150351 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! protein amino acid alkylation GO:0008213 59 26 1,000 9,639E-03 0,10106787 GO:0006479|protein amino acid methylation, ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 9,639E-03 0,10063596 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 9,639E-03 0,10020772 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 9,639E-03 0,09978311 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 1,000 9,639E-03 0,09936208 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! regulation of blood coagulation GO:0030193 46 26 1,000 9,639E-03 0,0989446 ! neural tube closure GO:0001843 58 26 1,000 9,639E-03 0,0985306 GO:0060606|tube closure, ! positive regulation of ligase activity GO:0051351 130 77 2,000 9,849E-03 0,10025647 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 1,000 0,01037163 0,10513645 ! tube lumen formation GO:0035148 59 27 1,000 0,01037163 0,104702 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 1,000 0,01037163 0,10427113 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 0,01037163 0,10384379 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 0,01037163 0,10341993 ! response to toxin GO:0009636 49 27 1,000 0,01037163 0,10299953 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 0,01037163 0,10258252 ! protein amino acid acylation GO:0043543 59 28 1,000 0,01112781 0,10961794 ! vesicle docking GO:0048278 55 28 1,000 0,01112781 0,10917771 ! group transfer coenzyme metabolic process GO:0006752 53 28 1,000 0,01112781 0,108741 ! regulation of peptidase activity GO:0052547 150 82 2,000 0,01167963 0,11367864 ! translational initiation GO:0006413 66 29 1,000 0,01190757 0,11543728 ! primary neural tube formation GO:0014020 61 29 1,000 0,01190757 0,114981 ! somitogenesis GO:0001756 52 29 1,000 0,01190757 0,11452832 ! T cell activation GO:0042110 189 84 2,000 0,01246285 0,11939901 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 0,0127106 0,1212969 ! immune response-activating signal transduction GO:0002757 58 30 1,000 0,0127106 0,12082493 GO:0002764|immune response-regulating signal transduction, ! regulation of B cell activation GO:0050864 55 30 1,000 0,0127106 0,12035661 ! regulation of coagulation GO:0050818 52 30 1,000 0,0127106 0,11989192 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 0,01353663 0,12719223 ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 0,01353663 0,12670491 ! nucleosome assembly GO:0006334 126 87 2,000 0,01369291 0,12767851 ! chromatin assembly GO:0031497 128 88 2,000 0,01411772 0,13113916 ! positive regulation of T cell proliferation GO:0042102 60 32 1,000 0,01438535 0,13311901 ! metanephros development GO:0001656 81 32 1,000 0,01438535 0,13261668 ! mesoderm formation GO:0001707 73 32 1,000 0,01438535 0,13211812 ! myeloid leukocyte activation GO:0002274 53 32 1,000 0,01438535 0,13162329 ! regulation of cell cycle process GO:0010564 161 90 2,000 0,01498966 0,13664079 ! cholesterol homeostasis GO:0042632 60 33 1,000 0,0152565 0,13855624 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 1,000 0,0152565 0,13804307 ! triglyceride metabolic process GO:0006641 46 33 1,000 0,0152565 0,13753368 ! regulation of calcium ion transport GO:0051924 60 33 1,000 0,0152565 0,13702804 ! ossification GO:0001503 205 91 2,000 0,0154368 0,13813958 ! gland development GO:0048732 220 91 2,000 0,0154368 0,13763542 ! bone development GO:0060348 206 92 2,000 0,01589141 0,14117354 ! protein-DNA complex assembly GO:0065004 134 92 2,000 0,01589141 0,14066204 ! cholesterol transport GO:0030301 62 34 1,000 0,01614978 0,14243293 ! formation of primary germ layer GO:0001704 76 34 1,000 0,01614978 0,14192058 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 0,01614978 0,1414119 ! adult locomotory behavior GO:0008344 62 34 1,000 0,01614978 0,14090686 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 2,000 0,01635351 0,14217658 GO:0010498|proteasomal protein catabolic process, ! membrane docking GO:0022406 69 35 1,000 0,01706493 0,14783552 ! sterol transport GO:0015918 63 35 1,000 0,01706493 0,14731313 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,01706493 0,14679442 ! positive regulation of endocytosis GO:0045807 56 35 1,000 0,01706493 0,14627936 ! mesoderm morphogenesis GO:0048332 80 35 1,000 0,01706493 0,14576789 ! nucleosome organization GO:0034728 143 95 2,000 0,01730018 0,14726251 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 1,000 0,01800165 0,15270153 ! leukocyte differentiation GO:0002521 232 98 2,000 0,01877653 0,15872344 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 0,01877653 0,15817612 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,01895969 0,15917019 ! xenobiotic metabolic process GO:0006805 55 37 1,000 0,01895969 0,15862508 ! odontogenesis GO:0042476 74 37 1,000 0,01895969 0,1580837 ! tissue remodeling GO:0048771 78 37 1,000 0,01895969 0,157546 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,01895969 0,15701195 ! negative regulation of cell activation GO:0050866 69 37 1,000 0,01895969 0,1564815 ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,01979842 0,16285363 GO:0060538|skeletal muscle organ development, ! positive regulation of immune response GO:0050778 175 100 2,000 0,01979842 0,16230714 ! neutral lipid metabolic process GO:0006638 54 38 1,000 0,01993877 0,16291105 GO:0006639|acylglycerol metabolic process, ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 0,01993877 0,16236802 ! regulation of protein stability GO:0031647 77 38 1,000 0,01993877 0,16182859 ! pigment metabolic process GO:0042440 87 38 1,000 0,01993877 0,16129273 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 0,01993877 0,16076041 ! neural tube formation GO:0001841 79 38 1,000 0,01993877 0,16023159 ! regulation of metal ion transport GO:0010959 71 39 1,000 0,02093861 0,16771483 ! erythrocyte homeostasis GO:0034101 75 39 1,000 0,02093861 0,16716674 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,02093861 0,16662223 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 93 40 1,000 0,02195896 0,17417445 ! nucleus organization GO:0006997 73 40 1,000 0,02195896 0,17361078 ! lipid homeostasis GO:0055088 75 40 1,000 0,02195896 0,17305074 ! glycerol ether metabolic process GO:0006662 57 40 1,000 0,02195896 0,17249431 ! Rho protein signal transduction GO:0007266 88 40 1,000 0,02195896 0,17194144 ! embryonic epithelial tube formation GO:0001838 85 41 1,000 0,02299954 0,17951399 ! organic ether metabolic process GO:0018904 59 42 1,000 0,0240601 0,18719372 ! T cell differentiation GO:0030217 93 42 1,000 0,0240601 0,18659945 ! ribonucleoside metabolic process GO:0009119 64 42 1,000 0,0240601 0,18600895 ! regulation of T cell differentiation GO:0045580 78 42 1,000 0,0240601 0,18542217 ! regulation of protein secretion GO:0050708 77 42 1,000 0,0240601 0,18483908 ! response to xenobiotic stimulus GO:0009410 63 42 1,000 0,0240601 0,18425965 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,02514038 0,19193108 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,02514038 0,19133316 ! segmentation GO:0035282 78 43 1,000 0,02514038 0,19073896 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 0,02735905 0,20692931 ! biopolymer methylation GO:0043414 91 45 1,000 0,02735905 0,20629064 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,0282334 0,21222831 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,0282334 0,21157731 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,0282334 0,21093028 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0282334 0,2102872 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,0282334 0,20964803 ! neuron fate determination GO:0048664 7 5 0,000 0,0282334 0,20901273 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0282334 0,20838127 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,0282334 0,20775362 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,0282334 0,20712973 ! polyol transport GO:0015791 12 5 0,000 0,0282334 0,20650959 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0282334 0,20589314 ! response to superoxide GO:0000303 10 5 0,000 0,0282334 0,20528036 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,0282334 0,20467122 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,0282334 0,20406569 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,0282334 0,20346372 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0282334 0,2028653 ! female meiosis GO:0007143 10 5 0,000 0,0282334 0,20227039 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,0282334 0,20167895 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0282334 0,20109097 ! hypothalamus development GO:0021854 9 5 0,000 0,0282334 0,2005064 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,0282334 0,19992522 ! cobalt ion transport GO:0006824 11 5 0,000 0,0282334 0,1993474 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,0282334 0,19877292 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,0282334 0,19820173 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0282334 0,19763382 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0282334 0,19706915 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,0282334 0,1965077 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,0282334 0,19594944 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0282334 0,19539434 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0282334 0,19484238 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,0282334 0,19429353 ! transposition GO:0032196 9 5 0,000 0,0282334 0,19374776 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,0282334 0,19320505 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,0282334 0,19266537 ! negative chemotaxis GO:0050919 16 5 0,000 0,0282334 0,1921287 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,0282334 0,191595 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0282334 0,19106427 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,0282334 0,19053647 ! behavioral response to pain GO:0048266 10 5 0,000 0,0282334 0,19001158 ! clathrin coat assembly GO:0048268 15 5 0,000 0,0282334 0,18948957 ! Notch receptor processing GO:0007220 11 5 0,000 0,0282334 0,18897042 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0282334 0,1884541 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,0282334 0,1879406 ! micturition GO:0060073 9 5 0,000 0,0282334 0,1874299 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0282334 0,18692196 ! copulation GO:0007620 9 5 0,000 0,0282334 0,18641676 ! glial cell fate commitment GO:0021781 14 5 0,000 0,0282334 0,18591429 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,0282334 0,18541452 ! bioluminescence GO:0008218 9 5 0,000 0,0282334 0,18491743 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0282334 0,184423 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0282334 0,1839312 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0282334 0,18344203 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,0282334 0,18295544 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0282334 0,18247143 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,0282334 0,18198998 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0282334 0,18151106 ! grooming behavior GO:0007625 6 5 0,000 0,0282334 0,18103465 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,0282334 0,18056074 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0282334 0,1800893 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,0282334 0,17962032 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0282334 0,17915377 ! response to protozoan GO:0001562 13 5 0,000 0,0282334 0,17868964 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,0282334 0,17822791 ! lymph vessel development GO:0001945 10 5 0,000 0,0282334 0,17776856 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,0282334 0,17731157 ! endochondral ossification GO:0001958 17 5 0,000 0,0282334 0,17685693 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0282334 0,17640461 ! single strand break repair GO:0000012 8 5 0,000 0,0282334 0,1759546 ! parathyroid gland development GO:0060017 14 5 0,000 0,0282334 0,17550687 ! anagen GO:0042640 7 5 0,000 0,0282334 0,17506143 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0282334 0,17461823 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,0282334 0,17417728 ! cytokine secretion GO:0050663 15 5 0,000 0,0282334 0,17373854 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,0282334 0,17330201 ! ceramide catabolic process GO:0046514 7 5 0,000 0,0282334 0,17286767 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,0282334 0,1724355 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,0282334 0,17200549 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0282334 0,17157762 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0282334 0,17115187 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,0282334 0,17072822 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,0282334 0,17030667 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0282334 0,1698872 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,0282334 0,16946978 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,0282334 0,16905442 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,0282334 0,16864108 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0282334 0,16822976 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,0282334 0,16782044 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0282334 0,16741311 ! valine metabolic process GO:0006573 12 5 0,000 0,0282334 0,16700775 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,0282334 0,16660435 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,0282334 0,1662029 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,0282334 0,16580337 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,0282334 0,16540576 ! polyol catabolic process GO:0046174 9 5 0,000 0,0282334 0,16501005 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,0282334 0,16461623 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,0282334 0,16422429 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,0282334 0,16383421 ! muscle cell migration GO:0014812 8 5 0,000 0,0282334 0,16344598 ! mitochondrial fission GO:0000266 8 5 0,000 0,0282334 0,16305958 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,0282334 0,162675 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,0282334 0,16229224 ! mRNA transcription GO:0009299 10 5 0,000 0,0282334 0,16191127 ! nerve growth factor processing GO:0032455 9 5 0,000 0,0282334 0,16153209 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,0282334 0,16115468 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,0282334 0,16077903 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,0282334 0,16040512 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,0282334 0,16003295 ! monocyte activation GO:0042117 10 5 0,000 0,0282334 0,1596625 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0282334 0,15929377 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0282334 0,15892673 ! response to food GO:0032094 6 5 0,000 0,0282334 0,15856138 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,0282334 0,15819771 ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,0282334 0,1578357 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0282334 0,15747535 ! forebrain neuron development GO:0021884 13 5 0,000 0,0282334 0,15711663 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0282334 0,15675955 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,0282334 0,15640409 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,0282334 0,15605023 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0282334 0,15569797 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0282334 0,1553473 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,0282334 0,15499821 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,0282334 0,15465068 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,0282334 0,1543047 ! lipid glycosylation GO:0030259 7 5 0,000 0,0282334 0,15396027 ! nucleobase transport GO:0015851 6 5 0,000 0,0282334 0,15361738 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,0282334 0,153276 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,0282334 0,15293615 ! basic amino acid transport GO:0015802 12 5 0,000 0,0282334 0,15259779 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,0282334 0,15226093 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,0282334 0,15192555 ! actin nucleation GO:0045010 11 5 0,000 0,0282334 0,15159165 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0282334 0,15125921 ! depurination GO:0045007 5 5 0,000 0,0282334 0,15092823 ! depyrimidination GO:0045008 10 5 0,000 0,0282334 0,15059869 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0282334 0,15027059 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0282334 0,14994392 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,0282334 0,14961866 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,0282334 0,14929481 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,0282334 0,14897236 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,0282334 0,1486513 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,0282334 0,14833162 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0282334 0,14801331 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0282334 0,14769636 ! activated T cell proliferation GO:0050798 16 5 0,000 0,0282334 0,14738077 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0282334 0,14706653 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,0282334 0,14675362 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0282334 0,14644204 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0282334 0,14613178 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,0282334 0,14582284 ! response to arsenic GO:0046685 11 5 0,000 0,0282334 0,14551519 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,0282334 0,14520885 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0282334 0,14490379 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,0282334 0,1446 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,0282334 0,14429749 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,0282334 0,14399625 ! response to mercury ion GO:0046689 8 5 0,000 0,0282334 0,14369625 ! response to cadmium ion GO:0046686 7 5 0,000 0,0282334 0,14339751 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,0282334 0,1431 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,0282334 0,14280373 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,0282334 0,14250868 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,0282334 0,14221485 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,0282334 0,14192223 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,0282334 0,1416308 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0282334 0,14134058 ! decidualization GO:0046697 11 5 0,000 0,0282334 0,14105154 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,0282334 0,14076368 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,0282334 0,14047699 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,0282334 0,14019147 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,0282334 0,1399071 ! embryonic cleavage GO:0040016 6 5 0,000 0,0282334 0,13962389 ! peroxisome fission GO:0016559 5 5 0,000 0,0282334 0,13934182 ! histone demethylation GO:0016577 13 5 0,000 0,0282334 0,13906089 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,0282334 0,13878109 ! mitotic recombination GO:0006312 9 5 0,000 0,0282334 0,13850241 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,0282334 0,13822485 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0282334 0,1379484 ! metaphase plate congression GO:0051310 7 5 0,000 0,0282334 0,13767306 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0282334 0,13739881 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,0282334 0,13712565 ! enteric nervous system development GO:0048484 8 5 0,000 0,0282334 0,13685357 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,0282334 0,13658258 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,0282334 0,13631265 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,0282334 0,13604379 ! muscle cell proliferation GO:0033002 12 5 0,000 0,0282334 0,13577599 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0282334 0,13550924 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,0282334 0,13524353 ! B cell homeostasis GO:0001782 13 5 0,000 0,0282334 0,13497887 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,0282334 0,13471524 ! metaphase GO:0051323 11 5 0,000 0,0282334 0,13445263 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,0282334 0,13419105 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,0282334 0,13393049 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0282334 0,13367093 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0282334 0,13341238 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,0282334 0,13315483 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,0282334 0,13289827 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0282334 0,1326427 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,0282334 0,1323881 ! response to redox state GO:0051775 6 5 0,000 0,0282334 0,13213449 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,0282334 0,13188184 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,0282334 0,13163016 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0282334 0,13137943 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,0282334 0,13112966 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,0282334 0,13088084 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0282334 0,13063296 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,0282334 0,13038601 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0282334 0,13014 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,0282334 0,12989492 ! striatum development GO:0021756 14 5 0,000 0,0282334 0,12965076 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,0282334 0,12940751 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0282334 0,12916517 ! glial cell migration GO:0008347 10 5 0,000 0,0282334 0,12892374 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,0282334 0,12868321 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,0282334 0,12844358 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,0282334 0,12820484 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0282334 0,12796698 ! T cell activation during immune response GO:0002286 9 5 0,000 0,0282334 0,12773 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0282334 0,1274939 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0282334 0,12725867 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,0282334 0,12702431 ! neuroprotection GO:0043526 8 5 0,000 0,0282334 0,12679081 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,0282334 0,12655817 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0282334 0,12632638 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,0282334 0,12609543 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,0282334 0,12586533 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,0282334 0,12563607 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0282334 0,12540764 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,0282334 0,12518004 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0282334 0,12495326 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,0282334 0,12472731 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,0282334 0,12450217 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0282334 0,12427784 ! spindle assembly GO:0051225 6 5 0,000 0,0282334 0,12405432 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,0282334 0,1238316 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0282334 0,12360968 ! protein palmitoylation GO:0018345 12 5 0,000 0,0282334 0,12338855 ! drug metabolic process GO:0017144 7 5 0,000 0,0282334 0,12316822 ! phospholipid scrambling GO:0017121 8 5 0,000 0,0282334 0,12294867 ! organ regeneration GO:0031100 7 5 0,000 0,0282334 0,1227299 ! carnitine metabolic process GO:0009437 8 5 0,000 0,0282334 0,1225119 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0282334 0,12229468 ! regulation of actin filament polymerization GO:0030833 99 46 1,000 0,02849694 0,12321776 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 1,000 0,02849694 0,12300006 ! pigmentation GO:0043473 103 46 1,000 0,02849694 0,12278313 ! cell growth GO:0016049 90 46 1,000 0,02849694 0,12256696 ! neural tube development GO:0021915 91 47 1,000 0,02965354 0,12731738 ! response to insulin stimulus GO:0032868 98 47 1,000 0,02965354 0,12709401 ! positive regulation of cell cycle GO:0045787 96 48 1,000 0,03082858 0,1318988 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 0,03082858 0,13166821 ! cellular component disassembly GO:0022411 89 48 1,000 0,03082858 0,13143842 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,03082858 0,13120943 ! male sex differentiation GO:0046661 93 48 1,000 0,03082858 0,13098124 ! methylation GO:0032259 97 48 1,000 0,03082858 0,13075385 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 0,03202183 0,13557941 ! regulation of ion transport GO:0043269 86 50 1,000 0,03323304 0,1404642 ! endocrine system development GO:0035270 109 50 1,000 0,03323304 0,1402216 ! activation of caspase activity GO:0006919 95 50 1,000 0,03323304 0,13997984 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03378417 0,14205632 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03378417 0,14181223 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03378417 0,14156899 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03378417 0,14132657 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03378417 0,14108499 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03378417 0,14084423 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03378417 0,14060429 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03378417 0,14036517 ! response to oxygen radical GO:0000305 11 6 0,000 0,03378417 0,14012686 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03378417 0,13988935 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03378417 0,13965266 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03378417 0,13941676 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03378417 0,13918165 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03378417 0,13894734 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03378417 0,13871381 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03378417 0,13848107 ! forebrain regionalization GO:0021871 9 6 0,000 0,03378417 0,13824911 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03378417 0,13801793 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03378417 0,13778751 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03378417 0,13755787 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03378417 0,13732898 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03378417 0,13710086 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03378417 0,1368735 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03378417 0,13664689 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03378417 0,13642102 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03378417 0,13619591 ! malate metabolic process GO:0006108 13 6 0,000 0,03378417 0,13597153 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03378417 0,13574789 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03378417 0,13552499 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03378417 0,13530282 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03378417 0,13508137 ! protein refolding GO:0042026 15 6 0,000 0,03378417 0,13486065 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03378417 0,13464065 ! opsonization GO:0008228 8 6 0,000 0,03378417 0,13442137 ! mating behavior GO:0007617 7 6 0,000 0,03378417 0,1342028 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03378417 0,13398493 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03378417 0,13376778 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03378417 0,13355133 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03378417 0,13333557 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03378417 0,13312052 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03378417 0,13290615 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03378417 0,13269247 ! toxin metabolic process GO:0009404 11 6 0,000 0,03378417 0,13247949 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,03378417 0,13226718 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03378417 0,13205555 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03378417 0,1318446 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,03378417 0,13163432 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03378417 0,13142471 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03378417 0,13121577 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03378417 0,13100749 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03378417 0,13079987 ! thymic T cell selection GO:0045061 16 6 0,000 0,03378417 0,13059291 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03378417 0,1303866 ! protein lipoylation GO:0009249 10 6 0,000 0,03378417 0,13018095 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03378417 0,12997594 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03378417 0,12977157 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03378417 0,12956785 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03378417 0,12936476 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03378417 0,12916232 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03378417 0,1289605 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03378417 0,12875931 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03378417 0,12855875 ! hyperosmotic response GO:0006972 10 6 0,000 0,03378417 0,12835882 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03378417 0,1281595 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03378417 0,12796081 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03378417 0,12776272 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03378417 0,12756525 ! urea metabolic process GO:0019627 7 6 0,000 0,03378417 0,12736839 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03378417 0,12717214 ! neutrophil activation GO:0042119 7 6 0,000 0,03378417 0,12697649 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03378417 0,12678144 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03378417 0,12658699 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03378417 0,12639314 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03378417 0,12619988 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03378417 0,12600721 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03378417 0,12581512 ! neuron apoptosis GO:0051402 15 6 0,000 0,03378417 0,12562362 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03378417 0,1254327 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03378417 0,12524237 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03378417 0,12505261 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03378417 0,12486342 ! carnitine transport GO:0015879 10 6 0,000 0,03378417 0,1246748 GO:0015838|betaine transport, ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03378417 0,12448676 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03378417 0,12429928 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,03378417 0,12411236 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03378417 0,12392601 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03378417 0,12374021 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03378417 0,12355497 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03378417 0,12337028 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03378417 0,12318615 ! establishment of spindle localization GO:0051293 16 6 0,000 0,03378417 0,12300256 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03378417 0,12281952 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03378417 0,12263703 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,03378417 0,12245507 ! response to UV-C GO:0010225 14 6 0,000 0,03378417 0,12227366 ! astrocyte development GO:0014002 16 6 0,000 0,03378417 0,12209278 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03378417 0,12191244 ! interaction with symbiont GO:0051702 14 6 0,000 0,03378417 0,12173262 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03378417 0,12155334 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03378417 0,12137459 ! response to copper ion GO:0046688 10 6 0,000 0,03378417 0,12119636 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03378417 0,12101865 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,03378417 0,12084146 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03378417 0,12066479 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03378417 0,12048864 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03378417 0,120313 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03378417 0,12013787 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03378417 0,11996325 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03378417 0,11978914 ! hair follicle maturation GO:0048820 8 6 0,000 0,03378417 0,11961554 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03378417 0,11944243 ! Schwann cell development GO:0014044 15 6 0,000 0,03378417 0,11926983 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03378417 0,11909772 ! response to pheromone GO:0019236 6 6 0,000 0,03378417 0,11892611 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03378417 0,11875499 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03378417 0,11858437 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03378417 0,11841423 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03378417 0,11824458 ! subpallium development GO:0021544 15 6 0,000 0,03378417 0,11807542 ! neural tube patterning GO:0021532 8 6 0,000 0,03378417 0,11790674 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03378417 0,11773854 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03378417 0,11757083 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03378417 0,11740358 ! G2 phase GO:0051319 16 6 0,000 0,03378417 0,11723682 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03378417 0,11707052 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03378417 0,1169047 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03378417 0,11673935 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03378417 0,11657446 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03378417 0,11641004 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03378417 0,11624608 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03378417 0,11608259 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03378417 0,11591955 ! receptor internalization GO:0031623 11 6 0,000 0,03378417 0,11575697 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,03378417 0,11559485 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,03378417 0,11543317 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03378417 0,11527195 ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03378417 0,11511118 ! protein deubiquitination GO:0016579 16 6 0,000 0,03378417 0,11495086 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,03378417 0,11479099 ! protein destabilization GO:0031648 9 6 0,000 0,03378417 0,11463155 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03378417 0,11447257 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03378417 0,11431402 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03378417 0,11415591 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03378417 0,11399823 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03378417 0,11384099 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03378417 0,11368419 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03378417 0,11352781 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03378417 0,11337187 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03378417 0,11321635 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03378417 0,11306126 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03378417 0,11290659 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03378417 0,11275235 ! neural plate development GO:0001840 9 6 0,000 0,03378417 0,11259853 ! catecholamine transport GO:0051937 9 6 0,000 0,03378417 0,11244512 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03378417 0,11229214 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03378417 0,11213956 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03378417 0,11198741 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,03378417 0,11183566 ! maternal placenta development GO:0001893 12 6 0,000 0,03378417 0,11168433 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03378417 0,1115334 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03378417 0,11138289 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03378417 0,11123278 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03378417 0,11108307 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03378417 0,11093376 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03378417 0,11078486 GO:0055081|anion homeostasis, ! negative regulation of immune system process GO:0002683 101 51 1,000 0,03446196 0,112856 ! positive regulation of binding GO:0051099 88 52 1,000 0,03570837 0,1167812 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,03570837 0,11662507 ! chromatin remodeling GO:0006338 122 53 1,000 0,03697202 0,120591 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,03825268 0,12460174 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 1,000 0,03825268 0,12443582 ! regulation of muscle contraction GO:0006937 94 54 1,000 0,03825268 0,12427035 ! membrane fusion GO:0006944 122 54 1,000 0,03825268 0,12410532 ! glutamine family amino acid metabolic process GO:0009064 85 54 1,000 0,03825268 0,12394072 ! regulation of cell shape GO:0008360 142 54 1,000 0,03825268 0,12377656 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 0,03825268 0,12361284 ! tRNA transcription GO:0009304 17 7 0,000 0,03930338 0,12684037 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03930338 0,12667303 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03930338 0,12650614 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03930338 0,12633968 ! regulation of helicase activity GO:0051095 16 7 0,000 0,03930338 0,12617366 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03930338 0,12600808 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03930338 0,12584293 ! sleep GO:0030431 16 7 0,000 0,03930338 0,12567822 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03930338 0,12551393 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03930338 0,12535008 ! prostate gland development GO:0030850 14 7 0,000 0,03930338 0,12518665 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03930338 0,12502364 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03930338 0,12486106 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03930338 0,12469891 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03930338 0,12453717 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03930338 0,12437585 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03930338 0,12421495 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03930338 0,12405447 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03930338 0,1238944 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03930338 0,12373474 ! glycolipid transport GO:0046836 11 7 0,000 0,03930338 0,12357549 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03930338 0,12341666 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03930338 0,12325823 ! neuron adhesion GO:0007158 14 7 0,000 0,03930338 0,1231002 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03930338 0,12294258 ! mRNA stabilization GO:0048255 18 7 0,000 0,03930338 0,12278537 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,03930338 0,12262855 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03930338 0,12247214 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03930338 0,12231613 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03930338 0,12216051 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03930338 0,12200528 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03930338 0,12185045 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03930338 0,12169602 ! lipoprotein transport GO:0042953 14 7 0,000 0,03930338 0,12154197 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03930338 0,12138832 ! rhythmic behavior GO:0007622 17 7 0,000 0,03930338 0,12123505 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03930338 0,12108217 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03930338 0,12092967 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03930338 0,12077756 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03930338 0,12062583 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03930338 0,12047448 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03930338 0,12032351 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03930338 0,12017291 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03930338 0,1200227 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03930338 0,11987286 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03930338 0,11972339 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03930338 0,11957429 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03930338 0,11942557 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03930338 0,11927722 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03930338 0,11912923 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03930338 0,11898161 ! spinal cord patterning GO:0021511 14 7 0,000 0,03930338 0,11883435 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03930338 0,11868746 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03930338 0,11854094 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03930338 0,11839477 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03930338 0,11824896 ! adrenal gland development GO:0030325 17 7 0,000 0,03930338 0,11810352 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03930338 0,11795843 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03930338 0,11781369 ! ovulation GO:0030728 10 7 0,000 0,03930338 0,11766931 ! adenohypophysis development GO:0021984 11 7 0,000 0,03930338 0,11752529 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03930338 0,11738161 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03930338 0,11723829 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03930338 0,11709532 ! microtubule nucleation GO:0007020 21 7 0,000 0,03930338 0,11695269 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03930338 0,11681041 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03930338 0,11666848 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03930338 0,11652689 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03930338 0,11638565 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03930338 0,11624474 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03930338 0,11610418 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03930338 0,11596396 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03930338 0,11582408 ! galactose metabolic process GO:0006012 13 7 0,000 0,03930338 0,11568453 ! response to dietary excess GO:0002021 8 7 0,000 0,03930338 0,11554532 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03930338 0,11540644 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03930338 0,1152679 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03930338 0,11512969 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03930338 0,11499181 ! organ growth GO:0035265 15 7 0,000 0,03930338 0,11485426 ! nucleoside transport GO:0015858 11 7 0,000 0,03930338 0,11471704 ! nucleoside salvage GO:0043174 11 7 0,000 0,03930338 0,11458014 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03930338 0,11444357 ! male sex determination GO:0030238 15 7 0,000 0,03930338 0,11430733 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03930338 0,11417141 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03930338 0,11403582 ! parturition GO:0007567 16 7 0,000 0,03930338 0,11390054 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03930338 0,11376559 ! rRNA modification GO:0000154 14 7 0,000 0,03930338 0,11363096 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03930338 0,11349664 ! spindle checkpoint GO:0031577 16 7 0,000 0,03930338 0,11336264 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03930338 0,11322896 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03930338 0,11309559 ! monocyte differentiation GO:0030224 16 7 0,000 0,03930338 0,11296254 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03930338 0,1128298 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03930338 0,11269737 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03930338 0,11256525 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03930338 0,11243344 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,03930338 0,11230194 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03930338 0,11217075 ! fibrinolysis GO:0042730 11 7 0,000 0,03930338 0,11203986 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,03930338 0,11190928 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03930338 0,111779 ! eating behavior GO:0042755 8 7 0,000 0,03930338 0,11164902 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03930338 0,11151935 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03930338 0,11138997 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03930338 0,1112609 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03930338 0,11113213 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03930338 0,11100365 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03930338 0,11087547 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03930338 0,11074759 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03930338 0,11062 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03930338 0,1104927 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03930338 0,1103657 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03930338 0,11023899 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03930338 0,11011257 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03930338 0,10998644 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03930338 0,10986059 ! histone ubiquitination GO:0016574 9 7 0,000 0,03930338 0,10973504 ! regulation of meiosis GO:0040020 12 7 0,000 0,03930338 0,10960977 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03930338 0,10948479 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03930338 0,10936009 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03930338 0,10923567 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03930338 0,10911154 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03930338 0,10898769 ! transcription termination GO:0006353 14 7 0,000 0,03930338 0,10886413 ! anaphase GO:0051322 18 7 0,000 0,03930338 0,10874084 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03930338 0,10861783 ! axonal fasciculation GO:0007413 19 7 0,000 0,03930338 0,10849509 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03930338 0,10837264 GO:0045839|negative regulation of mitosis, ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03930338 0,10825046 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03930338 0,10812856 ! diuresis GO:0030146 12 7 0,000 0,03930338 0,10800693 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03930338 0,10788557 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03930338 0,10776449 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03930338 0,10764368 ! antibiotic transport GO:0042891 9 7 0,000 0,03930338 0,10752313 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03930338 0,10740286 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03930338 0,10728286 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03930338 0,10716312 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03930338 0,10704365 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03930338 0,10692445 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03930338 0,10680552 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03930338 0,10668684 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03930338 0,10656843 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03930338 0,10645029 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03930338 0,1063324 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03930338 0,10621478 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03930338 0,10609741 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03930338 0,10598031 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03930338 0,10586346 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03930338 0,10574687 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03930338 0,10563054 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03930338 0,10551446 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03930338 0,10539864 ! muscle adaptation GO:0043500 13 7 0,000 0,03930338 0,10528307 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03930338 0,10516775 ! retina homeostasis GO:0001895 12 7 0,000 0,03930338 0,10505269 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03930338 0,10493788 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03930338 0,10482332 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03930338 0,10470901 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,03955011 0,10525156 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 1,000 0,03955011 0,10513703 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 1,000 0,03955011 0,10502275 ! response to UV GO:0009411 120 55 1,000 0,03955011 0,10490872 ! RNA elongation GO:0006354 90 56 1,000 0,04086409 0,10827654 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,04219437 0,11168023 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,04219437 0,11155937 ! regulation of actin filament length GO:0030832 118 58 1,000 0,04354075 0,11499464 ! positive regulation of cell migration GO:0030335 137 58 1,000 0,04354075 0,11487046 ! aging GO:0007568 112 58 1,000 0,04354075 0,11474654 ! gastrulation GO:0007369 122 58 1,000 0,04354075 0,11462289 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,04354075 0,11449951 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04479122 0,11766124 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04479122 0,11753486 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,04479122 0,11740875 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04479122 0,11728291 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04479122 0,11715734 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04479122 0,11703204 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04479122 0,116907 ! male meiosis GO:0007140 9 8 0,000 0,04479122 0,11678224 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04479122 0,11665773 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04479122 0,1165335 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04479122 0,11640953 ! meiotic prophase I GO:0007128 14 8 0,000 0,04479122 0,11628582 ! response to zinc ion GO:0010043 12 8 0,000 0,04479122 0,11616237 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,04479122 0,11603919 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04479122 0,11591627 ! oligopeptide transport GO:0006857 16 8 0,000 0,04479122 0,1157936 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04479122 0,1156712 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04479122 0,11554905 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04479122 0,11542717 ! signal peptide processing GO:0006465 12 8 0,000 0,04479122 0,11530554 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04479122 0,11518416 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04479122 0,11506304 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04479122 0,11494218 ! succinate metabolic process GO:0006105 17 8 0,000 0,04479122 0,11482157 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04479122 0,11470121 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04479122 0,1145811 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04479122 0,11446125 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04479122 0,11434165 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04479122 0,11422229 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04479122 0,11410319 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04479122 0,11398433 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04479122 0,11386572 ! reflex GO:0060004 17 8 0,000 0,04479122 0,11374735 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04479122 0,11362924 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04479122 0,11351136 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,04479122 0,11339374 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04479122 0,11327635 ! pigment granule organization GO:0048753 17 8 0,000 0,04479122 0,11315921 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04479122 0,11304231 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04479122 0,11292565 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04479122 0,11280923 ! astrocyte differentiation GO:0048708 19 8 0,000 0,04479122 0,11269305 ! histidine catabolic process GO:0006548 10 8 0,000 0,04479122 0,11257711 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04479122 0,11246141 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04479122 0,11234595 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04479122 0,11223072 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,04479122 0,11211573 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,04479122 0,11200098 ! melanin metabolic process GO:0006582 17 8 0,000 0,04479122 0,11188646 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04479122 0,11177217 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04479122 0,11165812 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04479122 0,1115443 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04479122 0,11143071 ! macrophage activation GO:0042116 13 8 0,000 0,04479122 0,11131735 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04479122 0,11120422 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,04479122 0,11109132 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04479122 0,11097866 ! purine salvage GO:0043101 12 8 0,000 0,04479122 0,11086622 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04479122 0,110754 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04479122 0,11064202 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04479122 0,11053026 ! osteoblast development GO:0002076 17 8 0,000 0,04479122 0,11041872 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04479122 0,11030741 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04479122 0,11019633 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,04479122 0,11008547 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04479122 0,10997483 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04479122 0,10986441 ! response to UV-B GO:0010224 17 8 0,000 0,04479122 0,10975422 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04479122 0,10964424 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04479122 0,10953449 ! intermediate filament organization GO:0045109 12 8 0,000 0,04479122 0,10942495 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04479122 0,10931564 ! cellular extravasation GO:0045123 13 8 0,000 0,04479122 0,10920654 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04479122 0,10909766 ! response to antibiotic GO:0046677 11 8 0,000 0,04479122 0,108989 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04479122 0,10888055 ! DNA topological change GO:0006265 12 8 0,000 0,04479122 0,10877232 ! response to tropane GO:0014073 15 8 0,000 0,04479122 0,1086643 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04479122 0,1085565 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04479122 0,10844891 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04479122 0,10834154 ! mast cell activation GO:0045576 14 8 0,000 0,04479122 0,10823438 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04479122 0,10812743 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04479122 0,10802069 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04479122 0,10791416 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04479122 0,10780784 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04479122 0,10770173 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04479122 0,10759583 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04479122 0,10749013 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,04479122 0,10738465 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04479122 0,10727937 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04479122 0,10717429 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04479122 0,10706943 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04479122 0,10696476 ! response to tumor cell GO:0002347 16 8 0,000 0,04479122 0,10686031 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04479122 0,10675605 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,04479122 0,106652 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04479122 0,10654815 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,04479122 0,10644451 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04479122 0,10634106 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04479122 0,10623782 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04479122 0,10613478 ! hormone catabolic process GO:0042447 17 8 0,000 0,04479122 0,10603193 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04479122 0,10592929 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04479122 0,10582684 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04479122 0,10572459 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04479122 0,10562254 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04479122 0,10552069 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04479122 0,10541903 ! adult feeding behavior GO:0008343 10 8 0,000 0,04479122 0,10531757 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04479122 0,1052163 ! ATP catabolic process GO:0006200 11 8 0,000 0,04479122 0,10511523 ! blastocyst growth GO:0001832 19 8 0,000 0,04479122 0,10501435 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04479122 0,10491367 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04479122 0,10481317 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04479122 0,10471288 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04479122 0,10461277 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04479122 0,10451285 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04479122 0,10441312 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04479122 0,10431359 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04479122 0,10421424 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04479122 0,10411509 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04479122 0,10401612 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04479122 0,10391734 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,04479122 0,10381874 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04479122 0,10372034 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04479122 0,10362212 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04479122 0,10352408 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04479122 0,10342623 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04479122 0,10332857 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04479122 0,10323109 ! lipid modification GO:0030258 112 60 1,000 0,04628085 0,10656373 ! DNA catabolic process GO:0006308 94 60 1,000 0,04628085 0,10646339 ! regulation of endocytosis GO:0030100 104 60 1,000 0,04628085 0,10636323 ! adult behavior GO:0030534 104 60 1,000 0,04628085 0,10626327 ! kidney development GO:0001822 133 60 1,000 0,04628085 0,10616349 ! regulation of cellular component size GO:0032535 125 61 1,000 0,04767414 0,10925696 ! nucleoside metabolic process GO:0009116 91 62 1,000 0,04908262 0,11237942 ! tRNA processing GO:0008033 102 62 1,000 0,04908262 0,1122742 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,04908262 0,11216917 ! axon extension GO:0048675 16 9 0,000 0,05024787 0,1147248 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,05024787 0,11461769 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05024787 0,11451077 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,05024787 0,11440405 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,05024787 0,11429752 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,05024787 0,1141912 ! reproductive behavior GO:0019098 22 9 0,000 0,05024787 0,11408508 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05024787 0,11397915 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,05024787 0,11387341 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,05024787 0,11376788 ! UTP metabolic process GO:0046051 10 9 0,000 0,05024787 0,11366254 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,05024787 0,11355739 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,05024787 0,11345244 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,05024787 0,11334768 ! artery development GO:0060840 25 9 0,000 0,05024787 0,11324312 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,05024787 0,11313875 ! regulation of glycolysis GO:0006110 20 9 0,000 0,05024787 0,11303457 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,05024787 0,11293058 ! equilibrioception GO:0050957 20 9 0,000 0,05024787 0,11282678 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,05024787 0,11272318 ! chemosensory behavior GO:0007635 21 9 0,000 0,05024787 0,11261976 ! microtubule bundle formation GO:0001578 22 9 0,000 0,05024787 0,11251654 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,05024787 0,1124135 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,05024787 0,11231065 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05024787 0,11220799 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,05024787 0,11210552 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,05024787 0,11200323 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,05024787 0,11190113 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,05024787 0,11179922 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05024787 0,11169749 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05024787 0,11159595 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,05024787 0,11149459 ! protein targeting to ER GO:0045047 25 9 0,000 0,05024787 0,11139341 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,05024787 0,11129242 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,05024787 0,11119161 ! T cell selection GO:0045058 27 9 0,000 0,05024787 0,11109099 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,05024787 0,11099054 ! glycine catabolic process GO:0006546 15 9 0,000 0,05024787 0,11089028 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,05024787 0,1107902 ! endosome organization GO:0007032 20 9 0,000 0,05024787 0,1106903 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05024787 0,11059058 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,05024787 0,11049104 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05024787 0,11039167 ! mannose metabolic process GO:0006013 13 9 0,000 0,05024787 0,11029249 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,05024787 0,11019348 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,05024787 0,11009466 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,05024787 0,109996 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,05024787 0,10989753 ! receptor clustering GO:0043113 20 9 0,000 0,05024787 0,10979923 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,05024787 0,10970111 ! retinol metabolic process GO:0042572 20 9 0,000 0,05024787 0,10960316 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,05024787 0,10950539 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,05024787 0,10940779 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,05024787 0,10931037 ! macrophage differentiation GO:0030225 15 9 0,000 0,05024787 0,10921312 ! oligodendrocyte development GO:0014003 11 9 0,000 0,05024787 0,10911604 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,05024787 0,10901913 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05024787 0,1089224 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,05024787 0,10882583 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05024787 0,10872944 ! response to amine stimulus GO:0014075 13 9 0,000 0,05024787 0,10863322 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05024787 0,10853717 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,05024787 0,10844129 ! erythrocyte development GO:0048821 17 9 0,000 0,05024787 0,10834558 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,05024787 0,10825004 ! renal water homeostasis GO:0003091 15 9 0,000 0,05024787 0,10815466 ! postreplication repair GO:0006301 25 9 0,000 0,05024787 0,10805946 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,05024787 0,10796442 ! icosanoid secretion GO:0032309 15 9 0,000 0,05024787 0,10786954 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05024787 0,10777484 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,05024787 0,1076803 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,05024787 0,10758593 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05024787 0,10749172 ! sterol catabolic process GO:0016127 14 9 0,000 0,05024787 0,10739767 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05024787 0,10730379 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,05024787 0,10721008 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,05024787 0,10711653 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,05024787 0,10702314 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,05024787 0,10692991 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,05024787 0,10683685 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,05024787 0,10674395 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,05024787 0,10665121 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,05024787 0,10655863 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,05024787 0,10646621 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05024787 0,10637395 ! pigment granule transport GO:0051904 17 9 0,000 0,05024787 0,10628185 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,05024787 0,10618991 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,05024787 0,10609813 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,05024787 0,10600651 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05024787 0,10591505 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,05024787 0,10582374 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,05024787 0,10573259 ! mitochondrion localization GO:0051646 18 9 0,000 0,05024787 0,1056416 ! regulation of mitosis GO:0007088 112 63 1,000 0,05050609 0,10609318 GO:0051783|regulation of nuclear division, ! response to peptide hormone stimulus GO:0043434 129 64 1,000 0,05194431 0,10902059 ! nucleoside monophosphate metabolic process GO:0009123 117 65 1,000 0,0533971 0,11197348 ! regulation of cytokine biosynthetic process GO:0042035 108 66 1,000 0,05486422 0,11495136 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,05486422 0,11485286 ! gonad development GO:0008406 115 66 1,000 0,05486422 0,11475453 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,0556735 0,1163476 ! regulation of developmental growth GO:0048638 16 10 0,000 0,0556735 0,11624816 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0556735 0,11614889 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,0556735 0,11604979 ! associative learning GO:0008306 21 10 0,000 0,0556735 0,11595085 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,0556735 0,11585209 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0556735 0,11575349 ! phosphate transport GO:0006817 24 10 0,000 0,0556735 0,11565506 ! cell volume homeostasis GO:0006884 17 10 0,000 0,0556735 0,1155568 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,0556735 0,1154587 ! CTP metabolic process GO:0046036 11 10 0,000 0,0556735 0,11536077 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,0556735 0,11526301 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,0556735 0,11516541 ! GTP metabolic process GO:0046039 11 10 0,000 0,0556735 0,11506798 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,0556735 0,11497071 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,0556735 0,11487361 ! social behavior GO:0035176 29 10 0,000 0,0556735 0,11477667 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,0556735 0,11467989 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,0556735 0,11458328 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,0556735 0,11448683 ! androgen metabolic process GO:0008209 17 10 0,000 0,0556735 0,11439054 ! phospholipid efflux GO:0033700 19 10 0,000 0,0556735 0,11429441 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0556735 0,11419845 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,0556735 0,11410264 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,0556735 0,114007 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,0556735 0,11391152 ! lung alveolus development GO:0048286 26 10 0,000 0,0556735 0,11381619 ! pathogenesis GO:0009405 17 10 0,000 0,0556735 0,11372103 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0556735 0,11362602 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,0556735 0,11353118 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,0556735 0,11343649 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,0556735 0,11334196 ! endoderm development GO:0007492 18 10 0,000 0,0556735 0,11324759 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,0556735 0,11315337 ! arginine catabolic process GO:0006527 17 10 0,000 0,0556735 0,11305931 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0556735 0,11296541 ! proline metabolic process GO:0006560 13 10 0,000 0,0556735 0,11287166 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,0556735 0,11277807 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,0556735 0,11268463 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,0556735 0,11259135 ! V(D)J recombination GO:0033151 34 10 0,000 0,0556735 0,11249822 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,0556735 0,11240525 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,0556735 0,11231243 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,0556735 0,11221976 ! B cell proliferation GO:0042100 19 10 0,000 0,0556735 0,11212725 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,0556735 0,11203488 ! multicellular organism growth GO:0035264 19 10 0,000 0,0556735 0,11194267 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,0556735 0,11185062 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,0556735 0,11175871 ! ruffle organization GO:0031529 17 10 0,000 0,0556735 0,11166695 ! epithelial cell development GO:0002064 21 10 0,000 0,0556735 0,11157535 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,0556735 0,11148389 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0556735 0,11139259 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,0556735 0,11130143 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,0556735 0,11121043 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,0556735 0,11111957 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,0556735 0,11102886 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,0556735 0,1109383 ! motor axon guidance GO:0008045 22 10 0,000 0,0556735 0,11084788 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0556735 0,11075761 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0556735 0,11066749 ! protein heterooligomerization GO:0051291 17 10 0,000 0,0556735 0,11057752 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0556735 0,11048769 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0556735 0,11039801 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,0556735 0,11030848 ! segment specification GO:0007379 15 10 0,000 0,0556735 0,11021908 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,0556735 0,11012984 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,0556735 0,11004074 ! blastoderm segmentation GO:0007350 19 10 0,000 0,0556735 0,10995178 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,0556735 0,10986296 ! response to dsRNA GO:0043331 23 10 0,000 0,0556735 0,10977429 ! DNA ligation GO:0006266 18 10 0,000 0,0556735 0,10968577 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,0556735 0,10959738 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0556735 0,10950914 ! melanosome localization GO:0032400 16 10 0,000 0,0556735 0,10942104 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,0556735 0,10933308 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,0556735 0,10924526 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,0556735 0,10915758 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0556735 0,10907005 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,0556735 0,10898265 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,0556735 0,1088954 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,0556735 0,10880828 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,0556735 0,1087213 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0556735 0,10863446 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0556735 0,10854777 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,0556735 0,1084612 ! salivary gland development GO:0007431 28 10 0,000 0,0556735 0,10837478 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,0556735 0,1082885 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,0556735 0,10820235 ! midbrain development GO:0030901 14 10 0,000 0,0556735 0,10811634 ! musculoskeletal movement GO:0050881 16 10 0,000 0,0556735 0,10803046 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,0556735 0,10794472 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,0556735 0,10785912 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,0556735 0,10777365 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,0556735 0,10768832 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,0556735 0,10760312 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0556735 0,10751806 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0556735 0,10743314 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,0556735 0,10734834 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,0556735 0,10726368 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,0556735 0,10717916 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0556735 0,10709476 ! blastocyst formation GO:0001825 18 10 0,000 0,0556735 0,1070105 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,0556735 0,10692638 ! cerebellar cortex development GO:0021695 16 10 0,000 0,0556735 0,10684238 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,0556735 0,10675852 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,0556735 0,10667478 ! response to nicotine GO:0035094 20 10 0,000 0,0556735 0,10659118 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,0556735 0,10650771 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,0556735 0,10642437 ! negative regulation of cell growth GO:0030308 142 67 1,000 0,05634547 0,1076247 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 1,000 0,05634547 0,10754062 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,05634547 0,10745667 ! regulation of lipase activity GO:0060191 137 68 1,000 0,05784065 0,11022208 ! adaptive immune response GO:0002250 126 68 1,000 0,05784065 0,11013617 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of cell size GO:0045792 144 69 1,000 0,05934955 0,11292129 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,05934955 0,11283342 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,05934955 0,11274568 ! activation of immune response GO:0002253 120 70 1,000 0,06087196 0,11554793 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,06106828 0,1158306 ! respiratory burst GO:0045730 17 11 0,000 0,06106828 0,11574074 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,06106828 0,11565101 ! neuron fate specification GO:0048665 18 11 0,000 0,06106828 0,11556143 ! telencephalon cell migration GO:0022029 23 11 0,000 0,06106828 0,11547199 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,06106828 0,11538268 ! synapsis GO:0007129 14 11 0,000 0,06106828 0,11529352 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,06106828 0,11520449 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,06106828 0,11511559 ! response to pain GO:0048265 27 11 0,000 0,06106828 0,11502684 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,06106828 0,11493822 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,06106828 0,11484974 ! blood vessel remodeling GO:0001974 30 11 0,000 0,06106828 0,11476139 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,06106828 0,11467318 ! bone resorption GO:0045453 16 11 0,000 0,06106828 0,11458511 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,06106828 0,11449717 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06106828 0,11440936 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06106828 0,11432169 ! melanocyte differentiation GO:0030318 20 11 0,000 0,06106828 0,11423416 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,06106828 0,11414676 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,06106828 0,11405949 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,06106828 0,11397235 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,06106828 0,11388535 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,06106828 0,11379848 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,06106828 0,11371174 ! UV protection GO:0009650 20 11 0,000 0,06106828 0,11362514 ! adult heart development GO:0007512 16 11 0,000 0,06106828 0,11353867 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,06106828 0,11345233 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06106828 0,11336612 ! temperature homeostasis GO:0001659 18 11 0,000 0,06106828 0,11328004 ! behavioral fear response GO:0001662 27 11 0,000 0,06106828 0,11319409 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,06106828 0,11310827 ! negative regulation of ossification GO:0030279 27 11 0,000 0,06106828 0,11302258 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,06106828 0,11293702 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,06106828 0,1128516 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,06106828 0,1127663 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,06106828 0,11268112 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,06106828 0,11259608 ! regulation of organ growth GO:0046620 14 11 0,000 0,06106828 0,11251117 ! pigment granule localization GO:0051875 20 11 0,000 0,06106828 0,11242638 ! vasoconstriction GO:0042310 20 11 0,000 0,06106828 0,11234172 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,06106828 0,11225719 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06106828 0,11217279 ! embryonic axis specification GO:0000578 19 11 0,000 0,06106828 0,11208851 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,06106828 0,11200436 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06106828 0,11192034 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,06106828 0,11183644 ! DNA methylation GO:0006306 19 11 0,000 0,06106828 0,11175267 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,06106828 0,11166902 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,06106828 0,1115855 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,06106828 0,1115021 ! prophase GO:0051324 17 11 0,000 0,06106828 0,11141883 ! neuroblast proliferation GO:0007405 25 11 0,000 0,06106828 0,11133568 ! nucleosome positioning GO:0016584 15 11 0,000 0,06106828 0,11125265 ! regulation of isotype switching GO:0045191 24 11 0,000 0,06106828 0,11116975 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,06106828 0,11108698 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,06106828 0,11100432 ! acid secretion GO:0046717 20 11 0,000 0,06106828 0,11092179 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06106828 0,11083938 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,06106828 0,1107571 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,06106828 0,11067493 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,06106828 0,11059289 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,06106828 0,11051097 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,06106828 0,11042917 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,06106828 0,11034749 ! cholesterol efflux GO:0033344 21 11 0,000 0,06106828 0,11026593 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06106828 0,1101845 ! oocyte development GO:0048599 20 11 0,000 0,06106828 0,11010318 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,06106828 0,11002198 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,06106828 0,10994091 ! embryonic gut development GO:0048566 19 11 0,000 0,06106828 0,10985995 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,06106828 0,10977911 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,06106828 0,10969839 ! activation of innate immune response GO:0002218 16 11 0,000 0,06106828 0,10961779 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,06106828 0,1095373 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,06106828 0,10945694 ! lysogeny GO:0030069 22 11 0,000 0,06106828 0,10937669 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06106828 0,10929656 ! sequestering of metal ion GO:0051238 15 11 0,000 0,06106828 0,10921655 ! regulation of embryonic development GO:0045995 35 11 0,000 0,06106828 0,10913666 ! nucleus localization GO:0051647 22 11 0,000 0,06106828 0,10905688 ! coenzyme biosynthetic process GO:0009108 119 72 1,000 0,06395651 0,11413131 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,06395651 0,114048 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,0664324 0,11837662 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,0664324 0,11829034 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,0664324 0,11820418 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,0664324 0,11811815 ! virus-host interaction GO:0019048 30 12 0,000 0,0664324 0,11803225 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,0664324 0,11794647 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,0664324 0,11786082 ! protein complex disassembly GO:0043241 28 12 0,000 0,0664324 0,11777529 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0664324 0,11768988 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,0664324 0,1176046 ! hippocampus development GO:0021766 29 12 0,000 0,0664324 0,11751944 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,0664324 0,1174344 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,0664324 0,11734949 ! T cell proliferation GO:0042098 32 12 0,000 0,0664324 0,1172647 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0664324 0,11718003 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,0664324 0,11709549 ! ventral spinal cord development GO:0021517 25 12 0,000 0,0664324 0,11701106 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,0664324 0,11692676 ! drug transport GO:0015893 16 12 0,000 0,0664324 0,11684258 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,0664324 0,11675852 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,0664324 0,11667458 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,0664324 0,11659076 ! polyamine metabolic process GO:0006595 18 12 0,000 0,0664324 0,11650707 ! focal adhesion formation GO:0048041 37 12 0,000 0,0664324 0,11642349 ! mitotic spindle organization GO:0007052 23 12 0,000 0,0664324 0,11634003 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,0664324 0,11625669 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,0664324 0,11617348 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,0664324 0,11609038 ! lipid digestion GO:0044241 21 12 0,000 0,0664324 0,11600739 ! entry into host cell GO:0030260 34 12 0,000 0,0664324 0,11592453 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0664324 0,11584179 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,0664324 0,11575916 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,0664324 0,11567665 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0664324 0,11559426 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,0664324 0,11551199 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,0664324 0,11542983 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,0664324 0,11534779 ! snRNA metabolic process GO:0016073 30 12 0,000 0,0664324 0,11526587 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,0664324 0,11518406 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,0664324 0,11510237 ! fucose catabolic process GO:0019317 25 12 0,000 0,0664324 0,1150208 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,0664324 0,11493934 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,0664324 0,11485799 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0664324 0,11477676 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,0664324 0,11469565 ! zymogen activation GO:0031638 18 12 0,000 0,0664324 0,11461465 ! T cell homeostasis GO:0043029 28 12 0,000 0,0664324 0,11453376 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,0664324 0,11445299 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,0664324 0,11437234 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,0664324 0,11429179 ! oocyte differentiation GO:0009994 21 12 0,000 0,0664324 0,11421136 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,0664324 0,11413104 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,0664324 0,11405084 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,0664324 0,11397075 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,0664324 0,11389077 ! defense response to fungus GO:0050832 15 12 0,000 0,0664324 0,1138109 ! embryonic placenta development GO:0001892 21 12 0,000 0,0664324 0,11373115 ! response to cold GO:0009409 17 12 0,000 0,0664324 0,1136515 ! establishment of cell polarity GO:0030010 21 12 0,000 0,0664324 0,11357197 ! regulation of synapse organization GO:0050807 18 12 0,000 0,0664324 0,11349255 ! regulation of caspase activity GO:0043281 136 74 1,000 0,06709273 0,11454056 ! reproductive structure development GO:0048608 131 75 1,000 0,06867972 0,11716799 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,06867972 0,11708623 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 0,07027905 0,11972923 ! learning or memory GO:0007611 161 76 1,000 0,07027905 0,11964579 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,07027905 0,11956247 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,07176602 0,12200722 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07176602 0,12192238 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 18 13 0,000 0,07176602 0,12183765 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07176602 0,12175304 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,07176602 0,12166855 ! peroxisomal transport GO:0043574 28 13 0,000 0,07176602 0,12158418 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,07176602 0,12149992 ! cartilage condensation GO:0001502 22 13 0,000 0,07176602 0,12141578 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,07176602 0,12133175 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,07176602 0,12124784 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,07176602 0,12116405 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,07176602 0,12108037 ! endocrine pancreas development GO:0031018 25 13 0,000 0,07176602 0,12099681 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,07176602 0,12091337 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,07176602 0,12083004 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,07176602 0,12074682 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,07176602 0,12066372 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,07176602 0,12058073 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07176602 0,12049786 ! methionine metabolic process GO:0006555 31 13 0,000 0,07176602 0,1204151 ! plasma membrane organization GO:0007009 27 13 0,000 0,07176602 0,12033245 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,07176602 0,12024992 ! Golgi organization GO:0007030 25 13 0,000 0,07176602 0,1201675 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,07176602 0,12008519 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,07176602 0,120003 ! cytokine metabolic process GO:0042107 24 13 0,000 0,07176602 0,11992092 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,07176602 0,11983895 ! exocrine system development GO:0035272 34 13 0,000 0,07176602 0,11975709 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,07176602 0,11967535 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,07176602 0,11959371 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,07176602 0,11951219 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,07176602 0,11943078 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,07176602 0,11934948 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,07176602 0,11926829 ! protein homotetramerization GO:0051289 24 13 0,000 0,07176602 0,11918721 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,07176602 0,11910624 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,07176602 0,11902538 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,07176602 0,11894463 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,07176602 0,11886399 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,07176602 0,11878346 ! chromatin silencing GO:0006342 29 13 0,000 0,07176602 0,11870303 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,07176602 0,11862272 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,07176602 0,11854252 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07176602 0,11846242 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,07176602 0,11838243 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,07176602 0,11830255 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,07176602 0,11822278 ! spleen development GO:0048536 24 13 0,000 0,07176602 0,11814311 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,07176602 0,11806356 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,07176602 0,11798411 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,07176602 0,11790476 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,07176602 0,11782552 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,07176602 0,11774639 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07176602 0,11766737 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,07176602 0,11758845 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,07176602 0,11750964 ! insulin secretion GO:0030073 24 13 0,000 0,07176602 0,11743093 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,07176602 0,11735233 ! acrosome reaction GO:0007340 19 13 0,000 0,07176602 0,11727383 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,07176602 0,11719544 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,07176602 0,11711715 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,07189051 0,117242 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,07189051 0,11716379 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 0,07189051 0,11708568 ! antigen processing and presentation GO:0019882 117 78 1,000 0,07351392 0,11964991 ! regulation of actin filament-based process GO:0032970 170 79 1,000 0,0751491 0,12222986 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,07679586 0,1248252 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,07679586 0,12474221 ! rRNA transcription GO:0009303 28 14 0,000 0,07706932 0,12510322 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,07706932 0,12502015 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,07706932 0,12493719 ! water transport GO:0006833 21 14 0,000 0,07706932 0,12485434 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,07706932 0,1247716 ! non-recombinational repair GO:0000726 29 14 0,000 0,07706932 0,12468897 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,07706932 0,12460645 ! RNA polyadenylation GO:0043631 32 14 0,000 0,07706932 0,12452403 ! palate development GO:0060021 32 14 0,000 0,07706932 0,12444173 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,07706932 0,12435954 ! regulated secretory pathway GO:0045055 24 14 0,000 0,07706932 0,12427745 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,07706932 0,12419547 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,07706932 0,12411361 ! arginine metabolic process GO:0006525 21 14 0,000 0,07706932 0,12403184 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,07706932 0,12395019 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,07706932 0,12386864 ! regulation of heart rate GO:0002027 25 14 0,000 0,07706932 0,12378721 ! fear response GO:0042596 34 14 0,000 0,07706932 0,12370587 ! organic alcohol transport GO:0015850 29 14 0,000 0,07706932 0,12362465 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,07706932 0,12354353 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,07706932 0,12346252 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07706932 0,12338161 ! neutral amino acid transport GO:0015804 28 14 0,000 0,07706932 0,12330081 ! bone mineralization GO:0030282 18 14 0,000 0,07706932 0,12322012 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,07706932 0,12313953 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,07706932 0,12305905 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,07706932 0,12297867 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,07706932 0,12289839 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,07706932 0,12281823 ! regulation of cellular pH GO:0030641 27 14 0,000 0,07706932 0,12273816 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,07706932 0,1226582 ! cerebellum development GO:0021549 23 14 0,000 0,07706932 0,12257835 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,07706932 0,12249859 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,07706932 0,12241895 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,07706932 0,1223394 ! response to gamma radiation GO:0010332 30 14 0,000 0,07706932 0,12225996 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,07706932 0,12218062 ! NADP metabolic process GO:0006739 24 14 0,000 0,07706932 0,12210139 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,07706932 0,12202225 ! oxygen transport GO:0015671 22 14 0,000 0,07706932 0,12194322 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07706932 0,1218643 ! male genitalia development GO:0030539 26 14 0,000 0,07706932 0,12178547 ! regulation of RNA stability GO:0043487 33 14 0,000 0,07706932 0,12170675 ! regulation of axon extension GO:0030516 43 14 0,000 0,07706932 0,12162813 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,07706932 0,12154961 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,078454 0,12365363 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,08180375 0,12885014 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08234246 0,1296151 ! lactation GO:0007595 30 15 0,000 0,08234246 0,12953164 ! reproductive cellular process GO:0048610 22 15 0,000 0,08234246 0,12944829 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08234246 0,12936504 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,08234246 0,1292819 ! superoxide anion generation GO:0042554 22 15 0,000 0,08234246 0,12919887 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,08234246 0,12911594 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,08234246 0,12903312 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,08234246 0,12895041 ! copper ion transport GO:0006825 22 15 0,000 0,08234246 0,1288678 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,08234246 0,1287853 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,08234246 0,1287029 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,08234246 0,12862061 ! sulfate transport GO:0008272 27 15 0,000 0,08234246 0,12853843 ! response to cAMP GO:0051591 25 15 0,000 0,08234246 0,12845635 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,08234246 0,12837437 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,08234246 0,1282925 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,08234246 0,12821073 ! response to hexose stimulus GO:0009746 25 15 0,000 0,08234246 0,12812907 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,08234246 0,12804751 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,08234246 0,12796605 ! vesicle coating GO:0006901 38 15 0,000 0,08234246 0,1278847 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,08234246 0,12780346 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,08234246 0,12772231 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,08234246 0,12764127 ! regulation of exocytosis GO:0017157 26 15 0,000 0,08234246 0,12756033 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,08234246 0,12747949 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,08234246 0,12739876 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,08234246 0,12731813 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,08234246 0,1272376 ! histone deacetylation GO:0016575 24 15 0,000 0,08234246 0,12715717 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,08234246 0,12707684 ! water homeostasis GO:0030104 28 15 0,000 0,08234246 0,12699662 ! cofactor transport GO:0051181 30 15 0,000 0,08234246 0,12691649 ! muscle maintenance GO:0046716 26 15 0,000 0,08234246 0,12683647 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,08234246 0,12675655 ! intestinal absorption GO:0050892 31 15 0,000 0,08234246 0,12667672 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08234246 0,126597 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,08234246 0,12651738 ! heme biosynthetic process GO:0006783 33 15 0,000 0,08234246 0,12643786 ! cell killing GO:0001906 32 15 0,000 0,08234246 0,12635844 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,08234246 0,12627912 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,08234246 0,1261999 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,08234246 0,12612078 ! actin filament polymerization GO:0030041 27 15 0,000 0,08234246 0,12604175 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,08234246 0,12596283 ! response to nutrient GO:0007584 135 84 1,000 0,083495 0,12764598 ! negative regulation of growth GO:0045926 168 85 1,000 0,08519691 0,13016639 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,08519691 0,13008503 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,08519691 0,13000378 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,08758563 0,13356535 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,08758563 0,13348203 ! positive regulation of cell size GO:0045793 29 16 0,000 0,08758563 0,13339881 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,08758563 0,1333157 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,08758563 0,13323269 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,08758563 0,13314978 ! bone remodeling GO:0046849 28 16 0,000 0,08758563 0,13306697 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,08758563 0,13298427 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,08758563 0,13290167 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08758563 0,13281918 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,08758563 0,13273678 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,08758563 0,13265449 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,08758563 0,1325723 ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,08758563 0,13249021 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,08758563 0,13240823 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,08758563 0,13232634 ! glutamate metabolic process GO:0006536 25 16 0,000 0,08758563 0,13224456 ! pituitary gland development GO:0021983 30 16 0,000 0,08758563 0,13216288 ! response to osmotic stress GO:0006970 27 16 0,000 0,08758563 0,13208129 ! lysosomal transport GO:0007041 31 16 0,000 0,08758563 0,13199981 ! fructose metabolic process GO:0006000 25 16 0,000 0,08758563 0,13191843 ! L-amino acid transport GO:0015807 33 16 0,000 0,08758563 0,13183715 ! stem cell development GO:0048864 46 16 0,000 0,08758563 0,13175597 GO:0019827|stem cell maintenance, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08758563 0,13167489 ! intermediate filament-based process GO:0045103 36 16 0,000 0,08758563 0,13159391 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,08758563 0,13151303 ! negative regulation of immune response GO:0050777 38 16 0,000 0,08758563 0,13143225 ! axon cargo transport GO:0008088 46 16 0,000 0,08758563 0,13135156 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,08758563 0,13127098 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,08758563 0,13119049 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,08758563 0,13111011 ! DNA replication initiation GO:0006270 28 16 0,000 0,08758563 0,13102982 ! neuron recognition GO:0008038 40 16 0,000 0,08758563 0,13094963 ! mRNA splice site selection GO:0006376 44 16 0,000 0,08758563 0,13086954 ! tissue regeneration GO:0042246 27 16 0,000 0,08758563 0,13078954 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,08758563 0,13070965 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,08758563 0,13062985 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,08758563 0,13055015 ! biomineral formation GO:0031214 22 16 0,000 0,08758563 0,13047055 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,08758563 0,13039104 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,08758563 0,13031163 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,08758563 0,13023232 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08758563 0,1301531 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,08758563 0,13007398 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,08758563 0,12999495 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,08758563 0,12991603 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,08758563 0,12983719 ! peptide hormone processing GO:0016486 27 16 0,000 0,08758563 0,12975846 ! mitochondrion organization GO:0007005 159 87 1,000 0,08863206 0,13122917 ! regulation of protein transport GO:0051223 165 87 1,000 0,08863206 0,13114969 GO:0070201|regulation of establishment of protein localization, ! one-carbon metabolic process GO:0006730 167 88 1,000 0,09036496 0,13363292 ! tube morphogenesis GO:0035239 194 89 1,000 0,09210783 0,13612791 ! regulation of neurological system process GO:0031644 175 89 1,000 0,09210783 0,1360456 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,09279899 0,13698364 ! metencephalon development GO:0022037 32 17 0,000 0,09279899 0,13690092 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,09279899 0,1368183 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,09279899 0,13673578 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,09279899 0,13665336 ! filopodium assembly GO:0046847 42 17 0,000 0,09279899 0,13657104 ! endothelial cell migration GO:0043542 31 17 0,000 0,09279899 0,13648882 ! gene silencing by RNA GO:0031047 38 17 0,000 0,09279899 0,13640669 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,09279899 0,13632467 ! glial cell development GO:0021782 28 17 0,000 0,09279899 0,13624274 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,09279899 0,13616092 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,09279899 0,13607919 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,09279899 0,13599756 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,09279899 0,13591602 ! myoblast differentiation GO:0045445 50 17 0,000 0,09279899 0,13583459 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,09279899 0,13575325 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,09279899 0,13567201 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,09279899 0,13559086 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,09279899 0,13550982 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,09279899 0,13542887 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,09279899 0,13534801 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,09279899 0,13526726 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,09279899 0,1351866 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,09279899 0,13510603 ! membrane budding GO:0006900 42 17 0,000 0,09279899 0,13502557 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,09279899 0,13494519 ! regulation of protein binding GO:0043393 33 17 0,000 0,09279899 0,13486492 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,09279899 0,13478474 ! genitalia development GO:0048806 32 17 0,000 0,09279899 0,13470465 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,09279899 0,13462466 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,09279899 0,13454476 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,09279899 0,13446496 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,09279899 0,13438525 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,09279899 0,13430564 ! steroid catabolic process GO:0006706 34 17 0,000 0,09279899 0,13422612 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,09279899 0,1341467 ! gas transport GO:0015669 26 17 0,000 0,09279899 0,13406737 ! organic cation transport GO:0015695 32 17 0,000 0,09279899 0,13398813 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,09279899 0,13390899 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,09279899 0,13382994 ! defense response to bacterium GO:0042742 112 91 1,000 0,09562285 0,13782101 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,09739466 0,14029195 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,0979827 0,14105583 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,0979827 0,14097275 ! limbic system development GO:0021761 40 18 0,000 0,0979827 0,14088978 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,0979827 0,1408069 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,0979827 0,14072413 ! adult walking behavior GO:0007628 36 18 0,000 0,0979827 0,14064144 ! patterning of blood vessels GO:0001569 43 18 0,000 0,0979827 0,14055886 ! heart looping GO:0001947 34 18 0,000 0,0979827 0,14047637 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,0979827 0,14039398 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,0979827 0,14031169 ! centrosome cycle GO:0007098 26 18 0,000 0,0979827 0,14022949 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,0979827 0,14014739 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,0979827 0,14006538 ! glycine metabolic process GO:0006544 30 18 0,000 0,0979827 0,13998347 ! response to retinoic acid GO:0032526 31 18 0,000 0,0979827 0,13990166 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,0979827 0,13981994 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,0979827 0,13973832 ! DNA integration GO:0015074 32 18 0,000 0,0979827 0,13965679 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,0979827 0,13957536 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,0979827 0,13949402 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,0979827 0,13941278 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,0979827 0,13933163 ! neural crest cell migration GO:0001755 41 18 0,000 0,0979827 0,13925057 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,0979827 0,13916961 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,0979827 0,13908875 GO:0046466|membrane lipid catabolic process, ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,0979827 0,13900798 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,0979827 0,1389273 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,0979827 0,13884672 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,0979827 0,13876622 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,0979827 0,13868583 ! detection of bacterium GO:0016045 22 18 0,000 0,0979827 0,13860552 ! defense response to virus GO:0051607 43 18 0,000 0,0979827 0,13852531 ! microspike assembly GO:0030035 46 18 0,000 0,0979827 0,13844519 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,0979827 0,13836517 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,0979827 0,13828523 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,09917578 0,13988824 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,09917578 0,13980752 ! regulation of membrane potential GO:0042391 179 94 1,000 0,10096606 0,14224918 ! ATP biosynthetic process GO:0006754 197 95 1,000 0,10276532 0,14470068 ! cofactor biosynthetic process GO:0051188 161 95 1,000 0,10276532 0,14461733 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,10276532 0,14453407 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,10313694 0,14497327 ! positive regulation of translation GO:0045727 31 19 0,000 0,10313694 0,1448899 ! negative regulation of defense response GO:0031348 27 19 0,000 0,10313694 0,14480663 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,10313694 0,14472346 ! neuron maturation GO:0042551 46 19 0,000 0,10313694 0,14464038 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,10313694 0,1445574 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,10313694 0,14447451 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,10313694 0,14439172 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,10313694 0,14430902 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,10313694 0,14422641 ! inositol metabolic process GO:0006020 33 19 0,000 0,10313694 0,1441439 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,10313694 0,14406149 ! memory GO:0007613 34 19 0,000 0,10313694 0,14397917 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,10313694 0,14389694 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,10313694 0,14381481 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,10313694 0,14373277 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,10313694 0,14365082 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,10313694 0,14356897 ! cerebral cortex development GO:0021987 40 19 0,000 0,10313694 0,14348721 ! pigmentation during development GO:0048066 42 19 0,000 0,10313694 0,14340555 ! response to vitamin A GO:0033189 32 19 0,000 0,10313694 0,14332397 ! heme metabolic process GO:0042168 40 19 0,000 0,10313694 0,14324249 ! neuromuscular junction development GO:0007528 43 19 0,000 0,10313694 0,1431611 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,10313694 0,14307981 ! response to fungus GO:0009620 26 19 0,000 0,10313694 0,14299861 ! peptide cross-linking GO:0018149 39 19 0,000 0,10313694 0,1429175 ! protein export from nucleus GO:0006611 40 19 0,000 0,10313694 0,14283648 ! heart process GO:0003015 32 19 0,000 0,10313694 0,14275555 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,10313694 0,14267471 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,10313694 0,14259397 ! visual learning GO:0008542 38 19 0,000 0,10313694 0,14251332 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,10313694 0,14243276 ! vitamin transport GO:0051180 31 19 0,000 0,10313694 0,14235229 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,10313694 0,14227191 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,10313694 0,14219162 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,10313694 0,14211142 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,10313694 0,14203131 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,10313694 0,14195129 ! cilium assembly GO:0042384 38 19 0,000 0,10313694 0,14187137 ! peptide hormone secretion GO:0030072 32 19 0,000 0,10313694 0,14179153 ! sex differentiation GO:0007548 171 96 1,000 0,10457342 0,14368552 ! protein secretion GO:0009306 45 20 0,000 0,10826187 0,1486699 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,10826187 0,14858638 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,10826187 0,14850295 ! positive regulation of ossification GO:0045778 50 20 0,000 0,10826187 0,14841961 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,10826187 0,14833637 ! skin development GO:0043588 42 20 0,000 0,10826187 0,14825322 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,10826187 0,14817017 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,10826187 0,14808721 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,10826187 0,14800434 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,10826187 0,14792156 ! response to vitamin GO:0033273 36 20 0,000 0,10826187 0,14783888 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,10826187 0,14775629 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,10826187 0,14767379 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,10826187 0,14759138 ! bile acid metabolic process GO:0008206 34 20 0,000 0,10826187 0,14750906 ! response to alkaloid GO:0043279 38 20 0,000 0,10826187 0,14742684 ! retinoid metabolic process GO:0001523 34 20 0,000 0,10826187 0,14734471 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,10826187 0,14726267 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,10826187 0,14718072 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,10826187 0,14709886 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,10826187 0,14701709 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,10826187 0,14693542 ! body fluid secretion GO:0007589 33 20 0,000 0,10826187 0,14685383 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,10826187 0,14677234 ! peptide secretion GO:0002790 38 20 0,000 0,10826187 0,14669093 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,10826187 0,14660962 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,10826187 0,1465284 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,10826187 0,14644726 ! cell-cell junction organization GO:0045216 43 20 0,000 0,10826187 0,14636622 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,10826187 0,14628526 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,10826187 0,1462044 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,10826187 0,14612362 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,10826187 0,14604293 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,10826187 0,14596234 ! regulation of glucose import GO:0046324 30 20 0,000 0,10826187 0,14588183 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,10826187 0,14580141 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,10826187 0,14572108 ! negative regulation of translation GO:0017148 32 20 0,000 0,10826187 0,14564083 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,10826187 0,14556068 ! mRNA transport GO:0051028 185 100 1,000 0,11189097 0,15035733 ! regulation of cell killing GO:0031341 46 21 0,000 0,11335766 0,15224451 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,11335766 0,15216086 ! hormone secretion GO:0046879 39 21 0,000 0,11335766 0,1520773 ! cAMP metabolic process GO:0046058 41 21 0,000 0,11335766 0,15199384 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,11335766 0,15191046 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,11335766 0,15182718 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,11335766 0,15174398 ! ovarian follicle development GO:0001541 39 21 0,000 0,11335766 0,15166088 ! smooth muscle contraction GO:0006939 48 21 0,000 0,11335766 0,15157787 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,11335766 0,15149495 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,11335766 0,15141212 ! plasma membrane fusion GO:0045026 33 21 0,000 0,11335766 0,15132938 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,11335766 0,15124673 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,11335766 0,15116417 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,11335766 0,15108171 ! diencephalon development GO:0021536 36 21 0,000 0,11335766 0,15099933 ! collagen fibril organization GO:0030199 62 21 0,000 0,11335766 0,15091704 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,11335766 0,15083484 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,11335766 0,15075273 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,11335766 0,15067071 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,11335766 0,15058878 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,11335766 0,15050694 ! collagen catabolic process GO:0030574 29 21 0,000 0,11335766 0,15042519 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,11335766 0,15034352 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,11335766 0,15026195 ! sperm-egg recognition GO:0035036 23 21 0,000 0,11335766 0,15018046 ! actin filament-based movement GO:0030048 47 21 0,000 0,11335766 0,15009906 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,11335766 0,15001775 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,11842447 0,15663833 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,11842447 0,15655357 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,11842447 0,1564689 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,11842447 0,15638432 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,11842447 0,15629983 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,11842447 0,15621544 ! microtubule-based transport GO:0010970 59 22 0,000 0,11842447 0,15613113 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,11842447 0,15604692 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,11842447 0,1559628 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,11842447 0,15587877 ! vacuolar transport GO:0007034 41 22 0,000 0,11842447 0,15579483 ! central nervous system neuron development GO:0021954 47 22 0,000 0,11842447 0,15571098 ! fucose metabolic process GO:0006004 44 22 0,000 0,11842447 0,15562721 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,11842447 0,15554354 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,11842447 0,15545996 ! ureteric bud development GO:0001657 50 22 0,000 0,11842447 0,15537647 ! cell aging GO:0007569 48 22 0,000 0,11842447 0,15529307 ! stem cell differentiation GO:0048863 57 22 0,000 0,11842447 0,15520976 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,11842447 0,15512654 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,11842447 0,1550434 ! cytolysis GO:0019835 27 22 0,000 0,11842447 0,15496036 ! renal system process GO:0003014 42 22 0,000 0,11842447 0,1548774 ! vasodilation GO:0042311 40 22 0,000 0,11842447 0,15479454 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,11842447 0,15471176 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,11842447 0,15462907 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,11842447 0,15454647 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,11842447 0,15446396 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,11842447 0,15438153 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,11842447 0,1542992 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,11842447 0,15421695 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,11842447 0,15413479 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,11842447 0,15405271 ! sarcomere organization GO:0045214 32 22 0,000 0,11842447 0,15397072 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,11842447 0,15388883 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,11842447 0,15380701 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,11842447 0,15372529 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,11842447 0,15364365 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,11842447 0,1535621 ! gut development GO:0048565 44 22 0,000 0,11842447 0,15348063 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,11842447 0,15339925 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,11842447 0,15331796 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,11842447 0,15323675 ! protein stabilization GO:0050821 41 22 0,000 0,11842447 0,15315563 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,12346247 0,15958668 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,12346247 0,15950229 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,12346247 0,15941798 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,12346247 0,15933377 ! gluconeogenesis GO:0006094 38 23 0,000 0,12346247 0,15924964 ! glycerol metabolic process GO:0006071 40 23 0,000 0,12346247 0,15916561 ! viral genome replication GO:0019079 44 23 0,000 0,12346247 0,15908166 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,12346247 0,1589978 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,12346247 0,15891403 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,12346247 0,15883035 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,12346247 0,15874675 ! regeneration GO:0031099 42 23 0,000 0,12346247 0,15866324 ! axis specification GO:0009798 43 23 0,000 0,12346247 0,15857982 ! visual behavior GO:0007632 46 23 0,000 0,12346247 0,15849649 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,12346247 0,15841325 ! response to ethanol GO:0045471 47 23 0,000 0,12346247 0,15833009 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,12346247 0,15824702 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,12346247 0,15816404 ! peroxisome organization GO:0007031 43 23 0,000 0,12346247 0,15808115 ! lysosome organization GO:0007040 47 23 0,000 0,12346247 0,15799834 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,12346247 0,15791562 ! vesicle targeting GO:0006903 49 23 0,000 0,12346247 0,15783298 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,12346247 0,15775043 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,12346247 0,15766797 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,12346247 0,15758559 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,12346247 0,1575033 ! DNA modification GO:0006304 36 23 0,000 0,12346247 0,1574211 ! fatty acid transport GO:0015908 47 23 0,000 0,12346247 0,15733898 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,12346247 0,15725695 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,12346247 0,157175 ! hormone transport GO:0009914 41 23 0,000 0,12346247 0,15709314 ! cell-cell recognition GO:0009988 28 23 0,000 0,12346247 0,15701136 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,12346247 0,15692967 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,12346247 0,15684806 GO:0006099|tricarboxylic acid cycle, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,12847182 0,16312717 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,12847182 0,16304242 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,12847182 0,16295777 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,12847182 0,16287321 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,12847182 0,16278873 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,12847182 0,16270434 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,12847182 0,16262003 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,12847182 0,16253582 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,12847182 0,16245169 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,12847182 0,16236765 ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,12847182 0,1622837 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,12847182 0,16219983 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,12847182 0,16211605 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,12847182 0,16203235 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,12847182 0,16194874 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,12847182 0,16186522 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,12847182 0,16178179 ! pallium development GO:0021543 56 24 0,000 0,12847182 0,16169844 ! oogenesis GO:0048477 44 24 0,000 0,12847182 0,16161517 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,12847182 0,161532 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,12847182 0,1614489 ! platelet activation GO:0030168 41 24 0,000 0,12847182 0,1613659 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,12847182 0,16128297 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,12847182 0,16120014 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,12847182 0,16111739 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,12847182 0,16103472 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,12847182 0,16095214 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,12847182 0,16086964 ! regulation of amine transport GO:0051952 41 24 0,000 0,12847182 0,16078723 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,13345269 0,16693544 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,13345269 0,16685001 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,13345269 0,16676466 ! leukocyte adhesion GO:0007159 55 25 0,000 0,13345269 0,1666794 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,13345269 0,16659423 ! phototransduction GO:0007602 37 25 0,000 0,13345269 0,16650915 ! keratinization GO:0031424 37 25 0,000 0,13345269 0,16642415 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,13345269 0,16633924 ! vacuole organization GO:0007033 49 25 0,000 0,13345269 0,16625442 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,13345269 0,16616968 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,13345269 0,16608503 ! receptor metabolic process GO:0043112 53 25 0,000 0,13345269 0,16600046 ! chromosome condensation GO:0030261 48 25 0,000 0,13345269 0,16591599 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,13345269 0,16583159 ! regulation of behavior GO:0050795 48 25 0,000 0,13345269 0,16574729 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,13345269 0,16566307 ! interaction with host GO:0051701 66 25 0,000 0,13345269 0,16557893 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,13345269 0,16549488 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,13345269 0,16541091 ! immunoglobulin production GO:0002377 62 25 0,000 0,13345269 0,16532704 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,13345269 0,16524324 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,13345269 0,16515953 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,13345269 0,16507591 ! liver development GO:0001889 55 25 0,000 0,13345269 0,16499236 ! protein tetramerization GO:0051262 57 25 0,000 0,13345269 0,16490891 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,13840522 0,17094234 ! myelination GO:0042552 50 26 0,000 0,13840522 0,17085597 ! initiation of viral infection GO:0019059 60 26 0,000 0,13840522 0,17076968 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,13840522 0,17068347 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,13840522 0,17059735 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,13840522 0,17051132 ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,13840522 0,17042538 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,13840522 0,17033952 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,13840522 0,17025375 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,13840522 0,17016807 ! digestive system process GO:0022600 49 26 0,000 0,13840522 0,17008247 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,13840522 0,16999696 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,13840522 0,16991154 ! osteoblast differentiation GO:0001649 63 26 0,000 0,13840522 0,1698262 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,13840522 0,16974094 ! neural crest cell development GO:0014032 59 26 0,000 0,13840522 0,16965577 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,13840522 0,16957069 ! negative regulation of cell development GO:0010721 83 26 0,000 0,13840522 0,16948569 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,13840522 0,16940078 ! pentose metabolic process GO:0019321 43 26 0,000 0,13840522 0,16931595 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,13840522 0,16923121 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,13840522 0,16914655 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,13840522 0,16906198 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,13840522 0,16897749 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,13840522 0,16889309 ! blastocyst development GO:0001824 50 26 0,000 0,13840522 0,16880877 ! telomere organization GO:0032200 46 26 0,000 0,13840522 0,16872453 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,13840522 0,16864038 ! alditol metabolic process GO:0019400 44 26 0,000 0,13840522 0,16855631 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,13840522 0,16847233 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,13840522 0,16838842 ! embryonic pattern specification GO:0009880 49 27 0,000 0,14332959 0,17429278 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,14332959 0,17420606 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,14332959 0,17411944 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,14332959 0,1740329 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,14332959 0,17394644 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,14332959 0,17386007 ! iron ion transport GO:0006826 65 27 0,000 0,14332959 0,17377379 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,14332959 0,17368759 ! superoxide metabolic process GO:0006801 41 27 0,000 0,14332959 0,17360148 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,14332959 0,17351546 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,14332959 0,17342951 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,14332959 0,17334366 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,14332959 0,17325789 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,14332959 0,1731722 ! leukocyte proliferation GO:0070661 59 27 0,000 0,14332959 0,1730866 GO:0032943|mononuclear cell proliferation, ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,14822595 0,17891107 ! neuron fate commitment GO:0048663 52 28 0,000 0,14822595 0,17882272 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,14822595 0,17873445 ! circadian rhythm GO:0007623 56 28 0,000 0,14822595 0,17864628 ! dendrite development GO:0016358 67 28 0,000 0,14822595 0,17855819 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,14822595 0,17847018 ! fat cell differentiation GO:0045444 57 28 0,000 0,14822595 0,17838227 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,14822595 0,17829444 ! sperm motility GO:0030317 37 28 0,000 0,14822595 0,17820669 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,14822595 0,17811904 ! base-excision repair GO:0006284 41 28 0,000 0,14822595 0,17803147 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,14822595 0,17794398 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,14822595 0,17785658 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,14822595 0,17776927 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,14822595 0,17768204 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,14822595 0,1775949 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,14822595 0,17750784 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,14822595 0,17742087 ! glutathione metabolic process GO:0006749 42 28 0,000 0,14822595 0,17733399 ! lipid oxidation GO:0034440 48 28 0,000 0,14822595 0,17724719 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,14822595 0,17716047 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,14822595 0,17707384 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,15309447 0,18280048 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,15309447 0,18271118 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,15309447 0,18262196 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,15309447 0,18253284 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,15309447 0,1824438 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,15309447 0,18235484 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,15309447 0,18226598 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,15309447 0,1821772 ! synaptogenesis GO:0007416 46 29 0,000 0,15309447 0,1820885 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,15309447 0,18199989 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,15309447 0,18191137 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,15309447 0,18182294 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,15309447 0,18173459 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,15793529 0,18738995 ! phenol metabolic process GO:0018958 56 30 0,000 0,15793529 0,18729899 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,15793529 0,18720811 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,15793529 0,18711732 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,15793529 0,18702662 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,15793529 0,186936 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,15793529 0,18684548 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,15793529 0,18675504 ! acute-phase response GO:0006953 50 30 0,000 0,15793529 0,18666469 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,15793529 0,18657443 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,15793529 0,18648425 ! myofibril assembly GO:0030239 50 30 0,000 0,15793529 0,18639416 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,15793529 0,18630416 ! cell fate determination GO:0001709 64 30 0,000 0,15793529 0,18621424 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,15793529 0,18612442 ! phospholipid transport GO:0015914 65 30 0,000 0,15793529 0,18603467 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,15793529 0,18594502 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,15793529 0,18585545 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,15793529 0,18576597 ! tissue homeostasis GO:0001894 50 30 0,000 0,15793529 0,18567657 GO:0048871|multicellular organismal homeostasis, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,16274858 0,19124328 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,16274858 0,19115133 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,16274858 0,19105948 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,16274858 0,19096771 ! cell junction assembly GO:0034329 85 31 0,000 0,16274858 0,19087603 ! regulation of innate immune response GO:0045088 57 31 0,000 0,16274858 0,19078444 ! ovulation cycle process GO:0022602 55 31 0,000 0,16274858 0,19069294 ! peptide transport GO:0015833 60 31 0,000 0,16274858 0,19060152 ! male gonad development GO:0008584 56 31 0,000 0,16274858 0,19051019 ! iron ion homeostasis GO:0055072 60 31 0,000 0,16274858 0,19041895 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,16274858 0,1903278 ! detection of light stimulus GO:0009583 44 31 0,000 0,16274858 0,19023674 ! natural killer cell activation GO:0030101 50 31 0,000 0,16274858 0,19014576 ! ensheathment of neurons GO:0007272 64 31 0,000 0,16274858 0,19005486 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,16274858 0,18996406 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,16274858 0,18987334 ! eye morphogenesis GO:0048592 65 31 0,000 0,16274858 0,18978271 ! response to heat GO:0009408 54 31 0,000 0,16274858 0,18969216 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,16753449 0,19517728 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,16753449 0,19508425 ! collagen metabolic process GO:0032963 49 32 0,000 0,16753449 0,19499131 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,16753449 0,19489846 ! spindle organization GO:0007051 50 32 0,000 0,16753449 0,19480569 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,16753449 0,19471301 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,16753449 0,19462043 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,16753449 0,19452793 ! muscle cell development GO:0055001 52 32 0,000 0,16753449 0,19443551 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,16753449 0,19434319 ! ovulation cycle GO:0042698 57 32 0,000 0,16753449 0,19425095 ! peripheral nervous system development GO:0007422 68 32 0,000 0,16753449 0,1941588 ! BMP signaling pathway GO:0030509 71 32 0,000 0,16753449 0,19406674 ! hindbrain development GO:0030902 65 32 0,000 0,16753449 0,19397477 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,16753449 0,19388288 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,16753449 0,19379108 ! gene silencing GO:0016458 71 32 0,000 0,16753449 0,19369936 ! regulation of pH GO:0006885 56 33 0,000 0,17229318 0,19910701 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,17229318 0,19901287 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,17229318 0,19891882 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,17229318 0,19882486 ! response to ionizing radiation GO:0010212 74 33 0,000 0,17229318 0,19873099 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,17229318 0,1986372 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,17229318 0,1985435 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,17229318 0,1984499 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,17229318 0,19835638 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,17229318 0,19826294 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,17229318 0,1981696 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,17702479 0,20351603 ! glial cell differentiation GO:0010001 67 34 0,000 0,17702479 0,20342031 ! post-embryonic development GO:0009791 76 34 0,000 0,17702479 0,20332467 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,17702479 0,20322912 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,17702479 0,20313366 ! spliceosome assembly GO:0000245 75 34 0,000 0,17702479 0,2030383 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,17702479 0,20294302 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,17702479 0,20284783 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,17702479 0,20275273 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,17702479 0,20265772 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,1817295 0,20794621 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,1817295 0,20784886 ! negative regulation of secretion GO:0051048 68 35 0,000 0,1817295 0,20775159 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,1817295 0,20765442 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,1817295 0,20755734 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,1817295 0,20746035 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,1817295 0,20736346 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,1817295 0,20726665 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,1817295 0,20716993 ! ceramide metabolic process GO:0006672 72 35 0,000 0,1817295 0,2070733 ! telencephalon development GO:0021537 81 35 0,000 0,1817295 0,20697676 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,1817295 0,20688032 ! placenta development GO:0001890 53 35 0,000 0,1817295 0,20678396 ! vesicle localization GO:0051648 70 35 0,000 0,1817295 0,20668769 ! regulation of muscle development GO:0048634 82 36 0,000 0,18640743 0,21190943 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,18640743 0,21181087 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,18640743 0,2117124 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,18640743 0,21161402 ! positive regulation of cell development GO:0010720 85 36 0,000 0,18640743 0,21151573 ! protein targeting to membrane GO:0006612 75 36 0,000 0,18640743 0,21141753 ! regulation of proteolysis GO:0030162 77 36 0,000 0,18640743 0,21131943 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,18640743 0,21122141 ! aerobic respiration GO:0009060 56 36 0,000 0,18640743 0,21112349 ! cytokine production GO:0001816 68 36 0,000 0,18640743 0,21102565 ! embryonic organ development GO:0048568 67 36 0,000 0,18640743 0,21092791 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,18640743 0,21083026 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,18640743 0,2107327 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,19105876 0,2158911 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,19105876 0,21579129 ! sister chromatid segregation GO:0000819 65 37 0,000 0,19105876 0,21569157 ! actomyosin structure organization GO:0031032 68 37 0,000 0,19105876 0,21559194 ! cell junction organization GO:0034330 96 37 0,000 0,19105876 0,21549241 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,19105876 0,21539296 ! female gonad development GO:0008585 71 37 0,000 0,19105876 0,21529361 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,19105876 0,21519435 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,19568363 0,22030189 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,19568363 0,22020041 ! meiosis I GO:0007127 74 38 0,000 0,19568363 0,22009903 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,19568363 0,21999774 ! organic anion transport GO:0015711 82 38 0,000 0,19568363 0,21989655 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,19568363 0,21979545 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,19568363 0,21969444 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,19568363 0,21959352 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,19568363 0,2194927 ! spermatid development GO:0007286 69 38 0,000 0,19568363 0,21939197 ! glycogen metabolic process GO:0005977 63 38 0,000 0,19568363 0,21929133 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,20028218 0,22434175 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,20028218 0,22423894 GO:0042593|glucose homeostasis, ! nucleotide catabolic process GO:0009166 70 39 0,000 0,20028218 0,22413622 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,20028218 0,22403359 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,20028218 0,22393106 ! glucan metabolic process GO:0044042 64 39 0,000 0,20028218 0,22382862 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,20485457 0,22883389 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,20485457 0,2287293 ! learning GO:0007612 82 40 0,000 0,20485457 0,22862481 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,20485457 0,22852042 GO:0046660|female sex differentiation, ! mismatch repair GO:0006298 58 40 0,000 0,20485457 0,22841612 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,20485457 0,22831191 ! RNA export from nucleus GO:0006405 61 41 0,000 0,20940094 0,23327246 ! mRNA catabolic process GO:0006402 79 41 0,000 0,20940094 0,23316614 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,20940094 0,23305991 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,20940094 0,23295378 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,20940094 0,23284775 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,20940094 0,23274181 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,20940094 0,23263597 ! gliogenesis GO:0042063 91 41 0,000 0,20940094 0,23253023 ! feeding behavior GO:0007631 69 41 0,000 0,20940094 0,23242458 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,20940094 0,23231903 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,20940094 0,23221358 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,20940094 0,23210822 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,20940094 0,23200295 ! spermatid differentiation GO:0048515 73 41 0,000 0,20940094 0,23189778 ! RNA modification GO:0009451 64 41 0,000 0,20940094 0,23179271 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,21392145 0,23668936 ! ear morphogenesis GO:0042471 64 42 0,000 0,21392145 0,23658221 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,21392145 0,23647516 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,21392145 0,23636821 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,21392145 0,23626135 ! cytokinesis GO:0000910 84 42 0,000 0,21392145 0,23615459 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,21841624 0,24100762 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,21841624 0,24089881 ! regulation of tube size GO:0035150 76 43 0,000 0,21841624 0,24079011 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,21841624 0,24068149 ! glucose transport GO:0015758 66 43 0,000 0,21841624 0,24057298 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,21841624 0,24046457 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,21841624 0,24035625 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,21841624 0,24024803 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,21841624 0,24013991 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,21841624 0,24003188 ! ion transmembrane transport GO:0034220 79 43 0,000 0,21841624 0,23992395 ! neuron migration GO:0001764 85 43 0,000 0,21841624 0,23981612 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,21841624 0,23970839 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,22288545 0,24450344 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,22288545 0,2443937 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,22288545 0,24428406 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,22288545 0,24417451 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,22288545 0,24406506 ! hexose transport GO:0008645 68 44 0,000 0,22288545 0,24395572 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,22288545 0,24384647 ! striated muscle contraction GO:0006941 85 44 0,000 0,22288545 0,24373731 ! phagocytosis GO:0006909 105 44 0,000 0,22288545 0,24362826 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,22288545 0,2435193 ! double-strand break repair GO:0006302 85 44 0,000 0,22288545 0,24341044 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,22732923 0,24815251 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,22732923 0,24804168 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,22732923 0,24793095 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,22732923 0,24782031 ! B cell differentiation GO:0030183 124 45 0,000 0,22732923 0,24770978 ! female gamete generation GO:0007292 71 45 0,000 0,22732923 0,24759934 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,22732923 0,247489 ! polyol metabolic process GO:0019751 77 45 0,000 0,22732923 0,24737876 ! developmental growth GO:0048589 88 45 0,000 0,22732923 0,24726862 ! maintenance of location in cell GO:0051651 101 45 0,000 0,22732923 0,24715858 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,23174773 0,2518504 ! glycolysis GO:0006096 71 46 0,000 0,23174773 0,25173842 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,23174773 0,25162653 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,23174773 0,25151475 ! leukocyte migration GO:0050900 75 46 0,000 0,23174773 0,25140307 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,23174773 0,25129148 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,23174773 0,25117999 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,23614108 0,25582823 ! positive regulation of defense response GO:0031349 88 48 0,000 0,24050943 0,26044528 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,24050943 0,26032988 ! mitochondrial transport GO:0006839 94 48 0,000 0,24050943 0,26021459 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,24050943 0,2600994 ! endosome transport GO:0016197 127 48 0,000 0,24050943 0,25998431 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,24050943 0,25986932 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,24050943 0,25975444 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,24050943 0,25963966 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,24050943 0,25952498 ! response to calcium ion GO:0051592 94 49 0,000 0,24485292 0,26409523 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,24485292 0,26397868 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,24485292 0,26386224 ! JNK cascade GO:0007254 106 49 0,000 0,24485292 0,2637459 ! regulation of action potential GO:0001508 102 50 0,000 0,2491717 0,26827962 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,2491717 0,26816143 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,2491717 0,26804335 ! regulation of ossification GO:0030278 123 50 0,000 0,2491717 0,26792538 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,2491717 0,2678075 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,2491717 0,26768973 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,2491717 0,26757207 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,2491717 0,26745451 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,25346589 0,2719443 ! viral infectious cycle GO:0019058 104 51 0,000 0,25346589 0,27182492 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,25346589 0,27170565 ! peptide metabolic process GO:0006518 80 51 0,000 0,25346589 0,27158648 ! response to temperature stimulus GO:0009266 84 51 0,000 0,25346589 0,27146742 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,25346589 0,27134846 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,25773565 0,27579859 ! Notch signaling pathway GO:0007219 111 52 0,000 0,25773565 0,27567784 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,25773565 0,27555719 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,25773565 0,27543665 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,25773565 0,27531622 ! excretion GO:0007588 87 52 0,000 0,25773565 0,27519589 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,25773565 0,27507566 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,25773565 0,27495554 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,25773565 0,27483552 ! amino acid activation GO:0043038 98 52 0,000 0,25773565 0,27471561 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,2619811 0,27911898 ! positive regulation of growth GO:0045927 96 53 0,000 0,2619811 0,27899731 ! inner ear development GO:0048839 89 53 0,000 0,2619811 0,27887574 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,2619811 0,27875428 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,2619811 0,27863293 ! cartilage development GO:0051216 99 53 0,000 0,2619811 0,27851168 ! synapse organization GO:0050808 102 53 0,000 0,2619811 0,27839053 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,26620239 0,28275324 ! regulation of translational initiation GO:0006446 87 54 0,000 0,26620239 0,28263035 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,26620239 0,28250758 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,26620239 0,28238491 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,26620239 0,28226235 ! RNA catabolic process GO:0006401 103 55 0,000 0,27039966 0,28658844 ! cell recognition GO:0008037 98 55 0,000 0,27039966 0,28646416 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,27039966 0,28633999 ! cell maturation GO:0048469 107 55 0,000 0,27039966 0,28621593 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,27457303 0,29050754 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,27457303 0,29038178 ! glucose catabolic process GO:0006007 88 56 0,000 0,27457303 0,29025613 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,27457303 0,29013059 ! regulation of DNA replication GO:0006275 105 56 0,000 0,27457303 0,29000515 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,27872265 0,29426078 ! muscle fiber development GO:0048747 131 57 0,000 0,27872265 0,29413366 ! heart morphogenesis GO:0003007 105 57 0,000 0,27872265 0,29400666 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,27872265 0,29387977 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,27872265 0,29375299 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,28284865 0,29797294 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,28284865 0,2978445 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,28284865 0,29771618 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,28284865 0,29758796 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,28284865 0,29745986 ! maintenance of location GO:0051235 124 58 0,000 0,28284865 0,29733186 ! nuclear export GO:0051168 110 59 0,000 0,28695116 0,3015147 ! establishment of organelle localization GO:0051656 122 59 0,000 0,28695116 0,30138507 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,29103032 0,30553806 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,29103032 0,30540682 ! positive regulation of secretion GO:0051047 110 61 0,000 0,29508625 0,30953015 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,29508625 0,3093973 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,29508625 0,30926457 ! regulation of heart contraction GO:0008016 123 61 0,000 0,29508625 0,30913195 ! proton transport GO:0015992 117 61 0,000 0,29508625 0,30899945 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,29508625 0,30886706 ! viral reproductive process GO:0022415 132 62 0,000 0,2991191 0,31295416 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,2991191 0,31282019 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,30312899 0,3168781 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,30312899 0,31674257 ! hydrogen transport GO:0006818 121 64 0,000 0,30711605 0,32077148 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,30711605 0,3206344 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,30711605 0,32049744 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,3110804 0,32449591 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,3110804 0,32435742 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,3110804 0,32421904 GO:0048609|reproductive process in a multicellular organism, ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,3110804 0,32408078 ! ear development GO:0043583 114 66 0,000 0,31502219 0,32804741 ! activation of MAPK activity GO:0000187 124 67 0,000 0,31894154 0,33198729 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,31894154 0,3318459 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,31894154 0,33170463 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,31894154 0,33156348 ! secondary metabolic process GO:0019748 125 67 0,000 0,31894154 0,33142245 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,32283856 0,33532934 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,32283856 0,33518683 ! hexose catabolic process GO:0019320 113 68 0,000 0,32283856 0,33504444 ! extracellular matrix organization GO:0030198 146 68 0,000 0,32283856 0,33490217 ! detection of external stimulus GO:0009581 102 68 0,000 0,32283856 0,33476002 ! viral reproduction GO:0016032 142 68 0,000 0,32283856 0,33461799 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,3267134 0,3384906 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,3267134 0,33834711 ! developmental maturation GO:0021700 128 69 0,000 0,3267134 0,33820375 ! single fertilization GO:0007338 83 69 0,000 0,3267134 0,3380605 ! cell redox homeostasis GO:0045454 114 70 0,000 0,33056618 0,34190227 ! germ cell development GO:0007281 133 70 0,000 0,33056618 0,34175758 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,33056618 0,34161302 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,33439701 0,34542575 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,33439701 0,34527976 ! appendage morphogenesis GO:0035107 150 72 0,000 0,33820603 0,34906521 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,33820603 0,3489178 ! B cell activation GO:0042113 179 72 0,000 0,33820603 0,34877051 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,33820603 0,34862335 ! appendage development GO:0048736 151 73 0,000 0,34199336 0,35237865 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,34199336 0,3522301 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,34199336 0,35208166 ! acute inflammatory response GO:0002526 118 74 0,000 0,34575913 0,35580857 ! amino acid transport GO:0006865 148 74 0,000 0,34575913 0,35565876 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,34575913 0,35550907 ! organelle localization GO:0051640 155 74 0,000 0,34575913 0,35535951 ! transition metal ion transport GO:0000041 143 75 0,000 0,34950344 0,35905673 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,34950344 0,35890581 ! rhythmic process GO:0048511 142 75 0,000 0,34950344 0,358755 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,35322643 0,36242427 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,35322643 0,36227212 ! regulation of blood pressure GO:0008217 134 76 0,000 0,35322643 0,36212009 ! amine catabolic process GO:0009310 136 77 0,000 0,35692822 0,3657616 ! neurotransmitter transport GO:0006836 142 77 0,000 0,35692822 0,36560824 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,35692822 0,36545501 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,35692822 0,36530191 ! regulation of catabolic process GO:0009894 173 77 0,000 0,35692822 0,36514893 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,36060893 0,36875999 ! fertilization GO:0009566 99 78 0,000 0,36060893 0,3686057 ! blood coagulation GO:0007596 151 79 0,000 0,36426867 0,37219087 GO:0050817|coagulation, ! steroid biosynthetic process GO:0006694 146 79 0,000 0,36426867 0,37203527 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,36426867 0,3718798 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,36426867 0,37172446 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,36790757 0,37528108 ! meiosis GO:0007126 143 81 0,000 0,37152574 0,37881359 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,37152574 0,37865556 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,37152574 0,37849765 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,3751233 0,38200342 ! protein import into nucleus GO:0006606 174 82 0,000 0,3751233 0,38184426 ! meiotic cell cycle GO:0051321 144 82 0,000 0,3751233 0,38168522 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,37870036 0,38516444 ! exocytosis GO:0006887 153 83 0,000 0,37870036 0,38500416 ! response to drug GO:0042493 149 83 0,000 0,37870036 0,38484401 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,37870036 0,38468399 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,37870036 0,3845241 ! nuclear import GO:0051170 177 83 0,000 0,37870036 0,38436435 ! response to metal ion GO:0010038 158 84 0,000 0,38225705 0,38781312 ! digestion GO:0007586 130 84 0,000 0,38225705 0,38765213 ! hemostasis GO:0007599 165 85 0,000 0,38579349 0,39107613 ! negative regulation of transport GO:0051051 164 85 0,000 0,38579349 0,39091393 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,38579349 0,39075186 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,38579349 0,39058992 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,38579349 0,39042812 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,38930977 0,39382351 ! regulation of lyase activity GO:0051339 169 86 0,000 0,38930977 0,3936605 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,39280602 0,39703149 ! alcohol catabolic process GO:0046164 142 87 0,000 0,39280602 0,39686729 ! cellular respiration GO:0045333 143 88 0,000 0,39628236 0,40021405 ! amine biosynthetic process GO:0009309 146 88 0,000 0,39628236 0,40004868 ! sensory perception of smell GO:0007608 117 88 0,000 0,39628236 0,39988343 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,39973888 0,40320483 ! cellular defense response GO:0006968 123 89 0,000 0,39973888 0,40303842 ! protein localization in nucleus GO:0034504 192 89 0,000 0,39973888 0,40287215 ! response to inorganic substance GO:0010035 173 90 0,000 0,40317572 0,40616836 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,40317572 0,40600094 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,40317572 0,40583366 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,40659297 0,40910487 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine transport GO:0015837 181 93 0,000 0,41336918 0,41575171 ! vitamin metabolic process GO:0006766 153 93 0,000 0,41336918 0,41558062 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,41672836 0,41878543 ! female pregnancy GO:0007565 166 94 0,000 0,41672836 0,41861323 ! sterol metabolic process GO:0016125 166 94 0,000 0,41672836 0,41844117 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,41672836 0,41826926 ! regulation of defense response GO:0031347 171 95 0,000 0,42006839 0,42144849 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,42006839 0,42127548 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,42006839 0,42110261 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,42669146 0,42756655 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,42669146 0,42739124 ! transcription initiation GO:0006352 171 97 0,000 0,42669146 0,42721608 ! forebrain development GO:0030900 210 98 0,000 0,42997472 0,43032701 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,42997472 0,43015079 ! hormone metabolic process GO:0042445 171 100 0,000 0,43648521 0,43648521