pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/966-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! glutathione biosynthetic process GO:0006750 13 11 4,000 7,245E-11 1,743E-07 ! peptide biosynthetic process GO:0043043 24 18 4,000 1,323E-09 1,591E-06 ! UTP metabolic process GO:0046051 8 8 3,000 4,1E-09 3,288E-06 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! CTP metabolic process GO:0046036 9 9 3,000 7,364E-09 4,43E-06 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 9 9 3,000 7,364E-09 3,544E-06 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 4,000 8,077E-09 3,239E-06 ! glutathione metabolic process GO:0006749 39 27 4,000 1,222E-08 4,2E-06 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 3,000 1,225E-08 3,683E-06 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 3,000 2,874E-08 7,684E-06 ! coenzyme biosynthetic process GO:0009108 102 69 5,000 4,392E-08 1,057E-05 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 3,000 5,788E-08 1,266E-05 ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 3,000 7,875E-08 1,579E-05 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 3,000 1,367E-07 2,53E-05 ! regulation of keratinocyte differentiation GO:0045616 6 5 2,000 2,161E-07 3,713E-05 ! cofactor biosynthetic process GO:0051188 139 91 5,000 2,324E-07 3,728E-05 ! peptide metabolic process GO:0006518 76 49 4,000 2,749E-07 4,134E-05 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 3,000 2,765E-07 3,914E-05 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 3,000 4,157E-07 5,557E-05 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 4,000 4,509E-07 5,71E-05 ! sulfur compound biosynthetic process GO:0044272 93 55 4,000 4,949E-07 5,953E-05 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 3,000 5,022E-07 5,753E-05 ! regulation of epidermal cell differentiation GO:0045604 8 7 2,000 7,532E-07 8,237E-05 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 3,000 8,424E-07 8,812E-05 ! vitamin biosynthetic process GO:0009110 39 28 3,000 1,149E-06 1,152E-04 ! positive regulation of epidermis development GO:0045684 13 8 2,000 1,203E-06 1,157E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 1,203E-06 1,113E-04 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 2,567E-06 2,287E-04 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 3,000 2,569E-06 2,207E-04 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 2,000 3,522E-06 2,922E-04 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 2,000 3,522E-06 2,825E-04 ! cartilage condensation GO:0001502 20 12 2,000 4,686E-06 3,637E-04 ! ribonucleoside metabolic process GO:0009119 55 40 3,000 4,997E-06 3,757E-04 ! regulation of monooxygenase activity GO:0032768 33 13 2,000 6,08E-06 4,433E-04 ! regulation of epidermis development GO:0045682 19 13 2,000 6,08E-06 4,302E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 6,704E-06 4,609E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 8,808E-06 5,887E-04 ! cartilage development GO:0051216 90 52 3,000 1,443E-05 9,38E-04 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 2,000 2,035E-05 1,288E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 2,082E-05 1,285E-03 ! nucleoside metabolic process GO:0009116 81 60 3,000 2,554E-05 1,536E-03 ! water-soluble vitamin metabolic process GO:0006767 95 62 3,000 2,909E-05 1,707E-03 ! positive regulation of cell motion GO:0051272 146 64 3,000 3,299E-05 1,89E-03 ! lung development GO:0030324 144 67 3,000 3,955E-05 2,213E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 4,207E-05 2,3E-03 ! respiratory tube development GO:0030323 150 70 3,000 4,7E-05 2,513E-03 ! respiratory system development GO:0060541 153 72 3,000 5,251E-05 2,747E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 5,382E-05 2,755E-03 ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 7,829E-05 3,924E-03 ! benzene and derivative metabolic process GO:0042537 12 5 1,000 7,829E-05 3,844E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 7,829E-05 3,767E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 7,829E-05 3,693E-03 ! tryptophan metabolic process GO:0006568 9 5 1,000 7,829E-05 3,622E-03 ! mRNA transcription GO:0009299 9 5 1,000 7,829E-05 3,554E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 7,829E-05 3,488E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 7,829E-05 3,425E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 7,829E-05 3,364E-03 ! response to hypoxia GO:0001666 171 81 3,000 8,33E-05 3,516E-03 ! response to oxygen levels GO:0070482 176 83 3,000 9,161E-05 3,8E-03 ! negative regulation of growth GO:0045926 155 84 3,000 9,599E-05 3,914E-03 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 1,172E-04 4,7E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 1,172E-04 4,623E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 1,172E-04 4,549E-03 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 1,172E-04 4,477E-03 ! embryonic hemopoiesis GO:0035162 14 6 1,000 1,172E-04 4,407E-03 ! response to interferon-gamma GO:0034341 15 6 1,000 1,172E-04 4,339E-03 ! ossification GO:0001503 188 90 3,000 1,255E-04 4,575E-03 ! bone development GO:0060348 189 91 3,000 1,31E-04 4,704E-03 ! vitamin metabolic process GO:0006766 139 92 3,000 1,366E-04 4,835E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 1,547E-04 5,394E-03 ! tissue remodeling GO:0048771 76 37 2,000 1,573E-04 5,406E-03 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 3,000 1,611E-04 5,458E-03 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! regulation of lipid kinase activity GO:0043550 13 7 1,000 1,638E-04 5,474E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,638E-04 5,399E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,638E-04 5,326E-03 ! mRNA stabilization GO:0048255 18 7 1,000 1,638E-04 5,255E-03 GO:0043489|RNA stabilization, ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 1,638E-04 5,186E-03 ! oxygen homeostasis GO:0032364 12 7 1,000 1,638E-04 5,118E-03 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 3,000 1,676E-04 5,171E-03 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 3,000 1,744E-04 5,311E-03 ! interphase GO:0051325 213 98 3,000 1,744E-04 5,245E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,18E-04 6,475E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 2,18E-04 6,396E-03 ! hemoglobin metabolic process GO:0020027 13 8 1,000 2,18E-04 6,319E-03 ! ER overload response GO:0006983 12 8 1,000 2,18E-04 6,244E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 2,18E-04 6,171E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 2,18E-04 6,099E-03 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 1,000 2,18E-04 6,029E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 2,18E-04 5,96E-03 ! NAD biosynthetic process GO:0009435 13 8 1,000 2,18E-04 5,893E-03 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 2,3E-04 6,149E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 2,798E-04 7,397E-03 ! induction of positive chemotaxis GO:0050930 15 9 1,000 2,798E-04 7,317E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 2,798E-04 7,238E-03 ! gas homeostasis GO:0033483 16 9 1,000 2,798E-04 7,161E-03 ! induction of an organ GO:0001759 14 9 1,000 2,798E-04 7,086E-03 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 2,798E-04 7,012E-03 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 2,798E-04 6,939E-03 ! positive regulation of DNA binding GO:0043388 73 47 2,000 3,216E-04 7,896E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 3,491E-04 8,484E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 3,491E-04 8,399E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 3,491E-04 8,316E-03 ! lung alveolus development GO:0048286 26 10 1,000 3,491E-04 8,234E-03 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 1,000 3,491E-04 8,154E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 3,491E-04 8,076E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 3,491E-04 7,999E-03 ! midbrain development GO:0030901 13 10 1,000 3,491E-04 7,923E-03 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 1,000 3,491E-04 7,849E-03 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 3,491E-04 7,777E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 3,491E-04 7,705E-03 GO:0043470|regulation of carbohydrate catabolic process, ! localization within membrane GO:0051668 20 10 1,000 3,491E-04 7,635E-03 ! positive regulation of binding GO:0051099 78 51 2,000 4,097E-04 8,88E-03 ! blood vessel remodeling GO:0001974 29 11 1,000 4,259E-04 9,148E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 4,259E-04 9,067E-03 ! indolalkylamine metabolic process GO:0006586 17 11 1,000 4,259E-04 8,988E-03 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 4,259E-04 8,91E-03 ! regulation of leukocyte migration GO:0002685 26 11 1,000 4,259E-04 8,833E-03 ! developmental induction GO:0031128 19 11 1,000 4,259E-04 8,757E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! response to UV GO:0009411 104 53 2,000 4,59E-04 9,359E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 5,101E-04 0,01031341 ! regulation of B cell proliferation GO:0030888 20 12 1,000 5,101E-04 0,01022746 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 5,101E-04 0,01014294 GO:0050927|positive regulation of positive chemotaxis, ! histone acetylation GO:0016573 26 12 1,000 5,101E-04 0,0100598 ! regulation of hormone metabolic process GO:0032350 26 12 1,000 5,101E-04 9,978E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 5,101E-04 9,898E-03 ! aromatic amino acid family catabolic process GO:0009074 18 12 1,000 5,101E-04 9,818E-03 ! biogenic amine catabolic process GO:0042402 23 12 1,000 5,101E-04 9,74E-03 ! regulation of RNA splicing GO:0043484 20 12 1,000 5,101E-04 9,664E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 5,101E-04 9,588E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 5,687E-04 0,01060627 ! regulation of bone remodeling GO:0046850 137 57 2,000 5,687E-04 0,01052469 ! regulation of tissue remodeling GO:0034103 140 58 2,000 5,985E-04 0,01099168 ! regulation of chemokine production GO:0032642 18 13 1,000 6,017E-04 0,01096803 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 6,017E-04 0,01088557 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! pyridine nucleotide biosynthetic process GO:0019363 19 13 1,000 6,017E-04 0,01080433 ! regulation of mRNA stability GO:0043488 31 13 1,000 6,017E-04 0,0107243 ! embryonic placenta development GO:0001892 23 13 1,000 6,017E-04 0,01064544 ! skeletal system morphogenesis GO:0048705 105 59 2,000 6,292E-04 0,01105087 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 7,007E-04 0,01221725 ! hair follicle morphogenesis GO:0031069 26 14 1,000 7,007E-04 0,01212936 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 7,007E-04 0,01204272 ! regulation of RNA stability GO:0043487 32 14 1,000 7,007E-04 0,01195731 ! regulation of homeostatic process GO:0032844 134 62 2,000 7,276E-04 0,01232821 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 8,071E-04 0,013579 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 8,071E-04 0,0134847 ! muscle maintenance GO:0046716 26 15 1,000 8,071E-04 0,0133917 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 8,071E-04 0,01329998 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 9,123E-04 0,01493212 ! negative regulation of cell growth GO:0030308 132 67 2,000 9,123E-04 0,01483123 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 9,207E-04 0,01486664 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 1,000 9,207E-04 0,01476753 ! cellular amino acid derivative catabolic process GO:0042219 29 16 1,000 9,207E-04 0,01466973 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 9,207E-04 0,01457322 ! negative regulation of kinase activity GO:0033673 131 68 2,000 9,525E-04 0,01497827 ! negative regulation of cell size GO:0045792 134 69 2,000 9,938E-04 0,01552588 ! heart looping GO:0001947 30 17 1,000 1,042E-03 0,01616697 ! myoblast differentiation GO:0045445 45 17 1,000 1,042E-03 0,01606334 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 1,042E-03 0,01596102 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 1,042E-03 0,01586 ! NAD metabolic process GO:0019674 29 17 1,000 1,042E-03 0,01576026 ! neural crest cell migration GO:0001755 37 17 1,000 1,042E-03 0,01566175 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 1,042E-03 0,01556448 ! negative regulation of transferase activity GO:0051348 140 72 2,000 1,124E-03 0,01669839 ! epidermis morphogenesis GO:0048730 40 18 1,000 1,17E-03 0,01726351 ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 1,17E-03 0,01715824 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 1,000 1,17E-03 0,01705425 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,17E-03 0,01695152 ! aromatic compound catabolic process GO:0019439 27 18 1,000 1,17E-03 0,01685001 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 1,17E-03 0,01674971 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 1,305E-03 0,01857542 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 1,305E-03 0,01846615 ! peptide cross-linking GO:0018149 37 19 1,000 1,305E-03 0,01835816 ! G1 phase GO:0051318 40 19 1,000 1,305E-03 0,01825143 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,447E-03 0,02012523 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 1,447E-03 0,02000956 ! response to vitamin GO:0033273 31 20 1,000 1,447E-03 0,01989522 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,447E-03 0,01978218 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 1,447E-03 0,01967042 ! peptidyl-serine modification GO:0018209 43 20 1,000 1,447E-03 0,01955991 ! muscle cell differentiation GO:0042692 159 80 2,000 1,524E-03 0,02048399 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 1,596E-03 0,0213395 ! positive regulation of locomotion GO:0040017 39 21 1,000 1,596E-03 0,02122161 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 1,596E-03 0,021105 ! response to cytokine stimulus GO:0034097 63 21 1,000 1,596E-03 0,02098968 ! regulation of chemotaxis GO:0050920 40 22 1,000 1,753E-03 0,02292114 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 1,753E-03 0,02279724 ! positive regulation of B cell activation GO:0050871 38 22 1,000 1,753E-03 0,02267467 ! aromatic amino acid family metabolic process GO:0009072 32 22 1,000 1,753E-03 0,02255342 ! regulation of DNA binding GO:0051101 155 88 2,000 2,003E-03 0,0256307 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 2,087E-03 0,02656431 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 2,087E-03 0,0264245 ! regulation of behavior GO:0050795 43 24 1,000 2,087E-03 0,02628615 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 2,087E-03 0,02614925 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 2,264E-03 0,02822411 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 2,264E-03 0,02807862 ! vasculogenesis GO:0001570 46 25 1,000 2,264E-03 0,02793463 ! osteoblast differentiation GO:0001649 60 25 1,000 2,264E-03 0,0277921 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 2,264E-03 0,02765103 ! neural crest cell development GO:0014032 54 25 1,000 2,264E-03 0,02751138 GO:0014033|neural crest cell differentiation, ! somitogenesis GO:0001756 43 25 1,000 2,264E-03 0,02737313 ! embryonic pattern specification GO:0009880 44 26 1,000 2,448E-03 0,02945199 ! molting cycle process GO:0022404 50 26 1,000 2,448E-03 0,02930547 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 2,448E-03 0,02916039 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 1,000 2,448E-03 0,02901674 ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 2,448E-03 0,0288745 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 2,639E-03 0,03097561 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 2,639E-03 0,03082524 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 2,639E-03 0,03067633 ! spliceosomal snRNP biogenesis GO:0000387 36 27 1,000 2,639E-03 0,03052884 ! protein amino acid acylation GO:0043543 55 27 1,000 2,639E-03 0,03038277 ! skeletal muscle tissue development GO:0007519 186 99 2,000 2,8E-03 0,03207489 GO:0060538|skeletal muscle organ development, ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 2,837E-03 0,03235053 ! cell cycle arrest GO:0007050 213 100 2,000 2,88E-03 0,03268878 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 3,042E-03 0,03435769 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 3,042E-03 0,03419714 ! nicotinamide metabolic process GO:0006769 52 30 1,000 3,253E-03 0,03640275 GO:0046496|nicotinamide nucleotide metabolic process, ! regulation of B cell activation GO:0050864 50 30 1,000 3,253E-03 0,03623421 ! alkaloid metabolic process GO:0009820 53 31 1,000 3,471E-03 0,0384842 ! collagen metabolic process GO:0032963 45 31 1,000 3,471E-03 0,03830767 ! iron ion homeostasis GO:0055072 54 31 1,000 3,471E-03 0,03813275 ! erythrocyte differentiation GO:0030218 55 31 1,000 3,471E-03 0,03795942 ! mesoderm formation GO:0001707 69 31 1,000 3,471E-03 0,03778765 ! BMP signaling pathway GO:0030509 64 32 1,000 3,696E-03 0,04005199 ! hindbrain development GO:0030902 61 32 1,000 3,696E-03 0,03987238 ! positive regulation of catabolic process GO:0009896 64 32 1,000 3,696E-03 0,03969438 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 3,927E-03 0,04199069 ! formation of primary germ layer GO:0001704 72 33 1,000 3,927E-03 0,04180489 ! cell fate specification GO:0001708 52 33 1,000 3,927E-03 0,04162073 ! pyridine nucleotide metabolic process GO:0019362 55 33 1,000 3,927E-03 0,04143818 ! xenobiotic metabolic process GO:0006805 51 34 1,000 4,165E-03 0,04375578 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 4,165E-03 0,04356553 ! mesoderm morphogenesis GO:0048332 76 34 1,000 4,165E-03 0,04337694 ! spermatid development GO:0007286 63 34 1,000 4,165E-03 0,04318997 ! placenta development GO:0001890 53 34 1,000 4,165E-03 0,0430046 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 4,409E-03 0,04533313 ! calcium-mediated signaling GO:0019722 62 35 1,000 4,409E-03 0,04514022 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 4,66E-03 0,04750616 ! embryonic organ development GO:0048568 57 36 1,000 4,66E-03 0,04730571 ! glycogen metabolic process GO:0005977 61 37 1,000 4,917E-03 0,04970792 ! spermatid differentiation GO:0048515 66 37 1,000 4,917E-03 0,04949993 ! carbohydrate homeostasis GO:0033500 53 38 1,000 5,181E-03 0,05193731 GO:0042593|glucose homeostasis, ! erythrocyte homeostasis GO:0034101 64 38 1,000 5,181E-03 0,0517218 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 5,181E-03 0,05150808 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 1,000 5,181E-03 0,05129611 GO:0006073|cellular glucan metabolic process, ! segmentation GO:0035282 67 39 1,000 5,451E-03 0,05374908 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 5,451E-03 0,05352969 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 5,727E-03 0,05601567 ! mesenchymal cell development GO:0014031 87 40 1,000 5,727E-03 0,05578889 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! cellular amide metabolic process GO:0043603 67 41 1,000 6,01E-03 0,05830688 ! hormone-mediated signaling GO:0009755 74 41 1,000 6,01E-03 0,05807272 ! keratinocyte differentiation GO:0030216 62 41 1,000 6,01E-03 0,05784042 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 6,299E-03 0,06038024 GO:0090047|positive regulation of transcription regulator activity, ! regulation of intracellular protein transport GO:0033157 80 42 1,000 6,299E-03 0,06014063 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 6,594E-03 0,06271054 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 6,594E-03 0,06246365 ! energy reserve metabolic process GO:0006112 74 43 1,000 6,594E-03 0,06221869 ! striated muscle cell differentiation GO:0051146 82 43 1,000 6,594E-03 0,06197565 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 6,594E-03 0,0617345 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 6,896E-03 0,0643062 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 7,203E-03 0,06691525 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 1,000 7,203E-03 0,06665788 ! cell growth GO:0016049 84 45 1,000 7,203E-03 0,06640249 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 7,517E-03 0,06902988 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 7,517E-03 0,06876741 ! epidermal cell differentiation GO:0009913 68 46 1,000 7,517E-03 0,06850693 ! positive regulation of protein transport GO:0051222 72 46 1,000 7,517E-03 0,06824841 ! vascular process in circulatory system GO:0003018 80 47 1,000 7,837E-03 0,07088441 ! positive regulation of cell cycle GO:0045787 89 48 1,000 8,163E-03 0,07355518 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 8,163E-03 0,07328072 ! regulation of ossification GO:0030278 117 50 1,000 8,832E-03 0,07899822 ! histone modification GO:0016570 91 50 1,000 8,832E-03 0,07870563 ! positive regulation of cytokine production GO:0001819 86 50 1,000 8,832E-03 0,0784152 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 9,176E-03 0,08116785 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 1,000 9,176E-03 0,08087053 ! regulation of angiogenesis GO:0045765 114 52 1,000 9,526E-03 0,08364599 ! covalent chromatin modification GO:0016569 101 52 1,000 9,526E-03 0,08334183 ! amino acid activation GO:0043038 92 52 1,000 9,526E-03 0,08303986 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! regulation of translational initiation GO:0006446 82 53 1,000 9,881E-03 0,08582844 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01024273 0,08864748 GO:0010863|positive regulation of phospholipase C activity, ! cell recognition GO:0008037 85 54 1,000 0,01024273 0,08832975 ! heterocycle catabolic process GO:0046700 85 54 1,000 0,01024273 0,08801428 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,01060993 0,09084512 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01060993 0,09052298 ! gastrulation GO:0007369 112 55 1,000 0,01060993 0,09020311 ! heart morphogenesis GO:0003007 97 55 1,000 0,01060993 0,08988549 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,01098289 0,09271873 ! muscle fiber development GO:0048747 112 57 1,000 0,01136159 0,09558038 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01136159 0,09524734 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,01136159 0,09491662 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01174599 0,0977884 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,01213605 0,10068736 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,01253174 0,10361294 ! mesoderm development GO:0007498 119 61 1,000 0,01293303 0,10656459 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,01375225 0,11292802 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,01375225 0,11254391 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,01375225 0,11216241 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01403313 0,11406657 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01403313 0,11368251 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01403313 0,11330102 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01403313 0,11292209 ! neuron fate determination GO:0048664 7 5 0,000 0,01403313 0,11254568 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01403313 0,11217177 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01403313 0,11180034 ! polyol transport GO:0015791 12 5 0,000 0,01403313 0,11143137 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01403313 0,11106482 ! response to superoxide GO:0000303 10 5 0,000 0,01403313 0,11070067 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01403313 0,1103389 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01403313 0,10997949 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01403313 0,10962242 ! female meiosis GO:0007143 7 5 0,000 0,01403313 0,10926765 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01403313 0,10891517 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01403313 0,10856496 ! cobalt ion transport GO:0006824 11 5 0,000 0,01403313 0,108217 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01403313 0,10787126 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01403313 0,10752772 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01403313 0,10718636 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01403313 0,10684716 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01403313 0,10651011 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01403313 0,10617517 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01403313 0,10584233 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01403313 0,10551158 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01403313 0,10518288 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01403313 0,10485622 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01403313 0,10453159 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01403313 0,10420896 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01403313 0,10388832 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01403313 0,10356964 ! negative chemotaxis GO:0050919 14 5 0,000 0,01403313 0,10325292 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01403313 0,10293812 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01403313 0,10262524 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01403313 0,10231425 ! behavioral response to pain GO:0048266 9 5 0,000 0,01403313 0,10200515 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01403313 0,1016979 ! Notch receptor processing GO:0007220 8 5 0,000 0,01403313 0,1013925 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01403313 0,10108893 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01403313 0,10078718 ! micturition GO:0060073 9 5 0,000 0,01403313 0,10048721 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01403313 0,10018903 ! copulation GO:0007620 9 5 0,000 0,01403313 0,09989262 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01403313 0,09959795 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01403313 0,09930501 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01403313 0,0990138 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01403313 0,09872428 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01403313 0,09843646 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01403313 0,0981503 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01403313 0,09786581 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01403313 0,09758296 ! grooming behavior GO:0007625 6 5 0,000 0,01403313 0,09730174 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01403313 0,09702214 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01403313 0,09674414 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01403313 0,09646773 ! response to protozoan GO:0001562 10 5 0,000 0,01403313 0,09619289 ! lymph vessel development GO:0001945 10 5 0,000 0,01403313 0,09591961 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01403313 0,09564789 ! endochondral ossification GO:0001958 16 5 0,000 0,01403313 0,0953777 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01403313 0,09510903 ! parathyroid gland development GO:0060017 13 5 0,000 0,01403313 0,09484187 ! anagen GO:0042640 6 5 0,000 0,01403313 0,0945762 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01403313 0,09431202 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01403313 0,09404932 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01403313 0,09378807 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01403313 0,09352827 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01403313 0,0932699 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01403313 0,09301296 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01403313 0,09275743 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01403313 0,0925033 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01403313 0,09225056 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01403313 0,09199919 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01403313 0,0917492 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01403313 0,09150055 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01403313 0,09125325 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01403313 0,09100729 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01403313 0,09076265 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01403313 0,09051931 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01403313 0,09027728 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01403313 0,09003654 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01403313 0,08979709 ! histidine catabolic process GO:0006548 6 5 0,000 0,01403313 0,0895589 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01403313 0,08932197 ! microvillus organization GO:0032528 7 5 0,000 0,01403313 0,08908629 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01403313 0,08885185 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01403313 0,08861865 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01403313 0,08838666 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01403313 0,08815589 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01403313 0,08792631 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01403313 0,08769793 ! polyol catabolic process GO:0046174 7 5 0,000 0,01403313 0,08747074 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01403313 0,08724471 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01403313 0,08701986 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01403313 0,08679615 ! muscle cell migration GO:0014812 8 5 0,000 0,01403313 0,0865736 ! mitochondrial fission GO:0000266 8 5 0,000 0,01403313 0,08635218 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01403313 0,0861319 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01403313 0,08591273 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01403313 0,08569468 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01403313 0,08547773 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01403313 0,08526188 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01403313 0,08504711 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01403313 0,08483343 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01403313 0,08462081 ! response to food GO:0032094 6 5 0,000 0,01403313 0,08440926 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01403313 0,08419876 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01403313 0,08398931 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01403313 0,0837809 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01403313 0,08357352 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01403313 0,08336717 ! forebrain neuron development GO:0021884 13 5 0,000 0,01403313 0,08316183 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01403313 0,0829575 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01403313 0,08275418 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01403313 0,08255184 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01403313 0,0823505 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01403313 0,08215013 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01403313 0,08195074 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01403313 0,08175231 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01403313 0,08155484 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01403313 0,08135832 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01403313 0,08116275 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01403313 0,08096812 ! basic amino acid transport GO:0015802 11 5 0,000 0,01403313 0,08077441 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01403313 0,08058163 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01403313 0,08038977 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01403313 0,08019882 ! depyrimidination GO:0045008 10 5 0,000 0,01403313 0,08000878 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01403313 0,07981963 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01403313 0,07963138 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01403313 0,07944401 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01403313 0,07925752 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01403313 0,07907191 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01403313 0,07888716 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01403313 0,07870327 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01403313 0,07852024 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01403313 0,07833806 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01403313 0,07815672 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01403313 0,07797622 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01403313 0,07779655 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01403313 0,07761771 ! response to arsenic GO:0046685 10 5 0,000 0,01403313 0,07743969 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01403313 0,07726248 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01403313 0,07708608 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01403313 0,07691049 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01403313 0,07673569 ! response to cadmium ion GO:0046686 7 5 0,000 0,01403313 0,07656169 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01403313 0,07638847 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01403313 0,07621604 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01403313 0,07604438 ! decidualization GO:0046697 11 5 0,000 0,01403313 0,07587349 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01403313 0,07570337 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01403313 0,07553401 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01403313 0,07536541 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01403313 0,07519756 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01403313 0,07503045 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01403313 0,07486409 ! neural tube patterning GO:0021532 7 5 0,000 0,01403313 0,07469846 ! embryonic cleavage GO:0040016 6 5 0,000 0,01403313 0,07453356 ! peroxisome fission GO:0016559 5 5 0,000 0,01403313 0,07436939 ! histone demethylation GO:0016577 10 5 0,000 0,01403313 0,07420594 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01403313 0,07404321 ! mitotic recombination GO:0006312 9 5 0,000 0,01403313 0,07388119 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01403313 0,07371988 ! metaphase plate congression GO:0051310 7 5 0,000 0,01403313 0,07355927 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01403313 0,07339936 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,01403313 0,07324014 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01403313 0,07308161 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01403313 0,07292377 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01403313 0,0727666 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01403313 0,07261012 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01403313 0,0724543 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01403313 0,07229915 ! plasminogen activation GO:0031639 5 5 0,000 0,01403313 0,07214467 ! B cell homeostasis GO:0001782 13 5 0,000 0,01403313 0,07199084 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01403313 0,07183767 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01403313 0,07168515 ! metaphase GO:0051323 8 5 0,000 0,01403313 0,07153327 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01403313 0,07138204 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01403313 0,07123144 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01403313 0,07108148 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01403313 0,07093215 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01403313 0,07078345 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01403313 0,07063536 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01403313 0,0704879 ! response to redox state GO:0051775 5 5 0,000 0,01403313 0,07034105 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01403313 0,07019481 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01403313 0,07004918 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01403313 0,06990415 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01403313 0,06975972 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01403313 0,06961588 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01403313 0,06947264 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01403313 0,06932999 ! striatum development GO:0021756 9 5 0,000 0,01403313 0,06918792 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01403313 0,06904643 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01403313 0,06890552 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01403313 0,06876518 ! glial cell migration GO:0008347 11 5 0,000 0,01403313 0,06862541 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01403313 0,06848622 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01403313 0,06834758 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01403313 0,0682095 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01403313 0,06807198 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01403313 0,06793502 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01403313 0,0677986 ! neuroprotection GO:0043526 6 5 0,000 0,01403313 0,06766273 ! neural plate development GO:0001840 8 5 0,000 0,01403313 0,06752741 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01403313 0,06739262 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01403313 0,06725837 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01403313 0,06712466 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01403313 0,06699148 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01403313 0,06685882 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01403313 0,06672669 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01403313 0,06659508 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01403313 0,06646398 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01403313 0,06633341 ! spindle assembly GO:0051225 6 5 0,000 0,01403313 0,06620334 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01403313 0,06607378 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01403313 0,06594473 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01403313 0,06581619 ! drug metabolic process GO:0017144 6 5 0,000 0,01403313 0,06568814 ! stem cell division GO:0017145 11 5 0,000 0,01403313 0,06556059 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01403313 0,06543354 ! organ regeneration GO:0031100 7 5 0,000 0,01403313 0,06530697 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01403313 0,0651809 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01403313 0,06505531 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01403313 0,0649302 ! germ cell development GO:0007281 118 65 1,000 0,01459345 0,06739316 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,01459345 0,06726405 ! secondary metabolic process GO:0019748 116 66 1,000 0,0150222 0,06910788 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,01545635 0,07096944 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,01545635 0,07083426 ! adaptive immune response GO:0002250 119 67 1,000 0,01545635 0,0706996 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,01589587 0,07257202 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01589587 0,07243457 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,0163407 0,07432086 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01681631 0,0763397 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01681631 0,07619593 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01681631 0,07605271 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01681631 0,07591002 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01681631 0,07576787 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01681631 0,07562624 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01681631 0,07548515 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01681631 0,07534458 ! sleep GO:0030431 13 6 0,000 0,01681631 0,07520454 ! response to oxygen radical GO:0000305 11 6 0,000 0,01681631 0,07506501 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01681631 0,074926 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01681631 0,07478751 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01681631 0,07464952 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01681631 0,07451205 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01681631 0,07437507 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01681631 0,07423861 ! forebrain regionalization GO:0021871 8 6 0,000 0,01681631 0,07410264 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01681631 0,07396717 ! male meiosis GO:0007140 7 6 0,000 0,01681631 0,07383219 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01681631 0,07369771 ! response to zinc ion GO:0010043 9 6 0,000 0,01681631 0,07356371 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01681631 0,0734302 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01681631 0,07329718 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01681631 0,07316463 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01681631 0,07303256 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01681631 0,07290097 ! malate metabolic process GO:0006108 11 6 0,000 0,01681631 0,07276986 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01681631 0,07263921 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01681631 0,07250903 ! protein refolding GO:0042026 15 6 0,000 0,01681631 0,07237932 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01681631 0,07225007 ! opsonization GO:0008228 8 6 0,000 0,01681631 0,07212128 ! mating behavior GO:0007617 7 6 0,000 0,01681631 0,07199295 ! neuron remodeling GO:0016322 15 6 0,000 0,01681631 0,07186508 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01681631 0,07173766 ! equilibrioception GO:0050957 14 6 0,000 0,01681631 0,07161069 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01681631 0,07148417 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01681631 0,0713581 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01681631 0,07123247 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01681631 0,07110728 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01681631 0,07098253 ! toxin metabolic process GO:0009404 11 6 0,000 0,01681631 0,07085821 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01681631 0,07073434 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01681631 0,07061089 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01681631 0,07048788 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01681631 0,07036529 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01681631 0,07024313 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01681631 0,07012139 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01681631 0,07000007 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01681631 0,06987917 ! thymic T cell selection GO:0045061 12 6 0,000 0,01681631 0,06975869 ! protein lipoylation GO:0009249 10 6 0,000 0,01681631 0,06963862 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01681631 0,06951897 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01681631 0,06939973 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01681631 0,06928089 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01681631 0,06916246 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01681631 0,06904444 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,01681631 0,06892682 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01681631 0,06880959 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01681631 0,06869277 ! hyperosmotic response GO:0006972 9 6 0,000 0,01681631 0,06857634 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01681631 0,06846031 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01681631 0,06834466 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01681631 0,06822941 ! urea metabolic process GO:0019627 7 6 0,000 0,01681631 0,06811455 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01681631 0,06800007 ! neutrophil activation GO:0042119 8 6 0,000 0,01681631 0,06788597 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01681631 0,06777226 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01681631 0,06765893 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01681631 0,06754598 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01681631 0,0674334 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01681631 0,0673212 ! neuron apoptosis GO:0051402 9 6 0,000 0,01681631 0,06720937 ! nucleoside salvage GO:0043174 9 6 0,000 0,01681631 0,06709791 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01681631 0,06698682 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01681631 0,0668761 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01681631 0,06676574 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01681631 0,06665575 ! carnitine transport GO:0015879 10 6 0,000 0,01681631 0,06654612 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01681631 0,06643685 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01681631 0,06632794 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01681631 0,06621938 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01681631 0,06611118 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01681631 0,06600333 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01681631 0,06589583 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01681631 0,06578868 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01681631 0,06568188 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01681631 0,06557543 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01681631 0,06546932 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01681631 0,06536356 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01681631 0,06525813 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01681631 0,06515304 ! neural nucleus development GO:0048857 14 6 0,000 0,01681631 0,0650483 ! response to UV-C GO:0010225 11 6 0,000 0,01681631 0,06494389 ! astrocyte development GO:0014002 15 6 0,000 0,01681631 0,06483981 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01681631 0,06473606 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01681631 0,06463265 ! interaction with symbiont GO:0051702 13 6 0,000 0,01681631 0,06452957 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01681631 0,06442682 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01681631 0,06432439 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01681631 0,06422229 ! response to copper ion GO:0046688 10 6 0,000 0,01681631 0,06412051 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01681631 0,06401905 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01681631 0,06391792 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01681631 0,0638171 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01681631 0,0637166 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01681631 0,06361642 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01681631 0,06351655 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01681631 0,06341699 ! hair follicle maturation GO:0048820 7 6 0,000 0,01681631 0,06331775 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01681631 0,06321881 ! Schwann cell development GO:0014044 15 6 0,000 0,01681631 0,06312019 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01681631 0,06302187 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01681631 0,06292386 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01681631 0,06282615 ! subpallium development GO:0021544 10 6 0,000 0,01681631 0,06272875 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01681631 0,06263164 ! histone ubiquitination GO:0016574 8 6 0,000 0,01681631 0,06253484 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01681631 0,06243833 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01681631 0,06234213 ! G2 phase GO:0051319 16 6 0,000 0,01681631 0,06224622 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01681631 0,0621506 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01681631 0,06205528 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01681631 0,06196025 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01681631 0,06186551 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01681631 0,06177105 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01681631 0,06167689 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01681631 0,06158301 ! receptor internalization GO:0031623 10 6 0,000 0,01681631 0,06148942 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01681631 0,06139612 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01681631 0,06130309 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01681631 0,06121035 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01681631 0,06111789 ! protein deubiquitination GO:0016579 14 6 0,000 0,01681631 0,0610257 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01681631 0,0609338 ! protein destabilization GO:0031648 9 6 0,000 0,01681631 0,06084217 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01681631 0,06075081 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01681631 0,06065973 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01681631 0,06056892 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01681631 0,06047839 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01681631 0,06038812 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01681631 0,06029812 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01681631 0,06020839 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01681631 0,06011893 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01681631 0,06002973 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01681631 0,0599408 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01681631 0,05985213 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01681631 0,05976372 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01681631 0,05967558 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01681631 0,05958769 ! catecholamine transport GO:0051937 9 6 0,000 0,01681631 0,05950006 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01681631 0,05941269 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01681631 0,05932557 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01681631 0,05923871 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01681631 0,05915211 ! maternal placenta development GO:0001893 12 6 0,000 0,01681631 0,05906575 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01681631 0,05897965 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01681631 0,0588938 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01681631 0,0588082 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01681631 0,05872285 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01681631 0,05863774 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01681631 0,05855288 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01681631 0,05846827 ! amine catabolic process GO:0009310 117 71 1,000 0,01724623 0,05987654 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,01864367 0,06463498 GO:0090046|regulation of transcription regulator activity, ! cell-matrix adhesion GO:0007160 163 75 1,000 0,01911979 0,06619025 ! tRNA transcription GO:0009304 14 7 0,000 0,01959173 0,06772658 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01959173 0,06762941 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01959173 0,06753252 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01959173 0,0674359 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01959173 0,06733957 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01959173 0,0672435 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01959173 0,06714772 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01959173 0,0670522 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01959173 0,06695696 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01959173 0,06686198 ! prostate gland development GO:0030850 13 7 0,000 0,01959173 0,06676728 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01959173 0,06667284 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01959173 0,06657867 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01959173 0,06648476 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01959173 0,06639112 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01959173 0,06629774 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01959173 0,06620463 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01959173 0,06611178 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01959173 0,06601918 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01959173 0,06592685 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01959173 0,06583477 ! glycolipid transport GO:0046836 10 7 0,000 0,01959173 0,06574295 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01959173 0,06565139 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,01959173 0,06556008 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01959173 0,06546902 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01959173 0,06537822 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01959173 0,06528767 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01959173 0,06519737 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01959173 0,06510732 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01959173 0,06501751 ! pericardium development GO:0060039 14 7 0,000 0,01959173 0,06492796 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01959173 0,06483865 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01959173 0,06474958 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01959173 0,06466076 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01959173 0,06457219 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01959173 0,06448385 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01959173 0,06439576 ! lipoprotein transport GO:0042953 14 7 0,000 0,01959173 0,06430791 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01959173 0,06422029 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01959173 0,06413292 ! rhythmic behavior GO:0007622 15 7 0,000 0,01959173 0,06404578 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01959173 0,06395888 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01959173 0,06387222 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01959173 0,06378579 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01959173 0,06369959 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01959173 0,06361363 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01959173 0,06352789 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01959173 0,06344239 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01959173 0,06335712 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01959173 0,06327208 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01959173 0,06318726 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01959173 0,06310267 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01959173 0,06301831 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01959173 0,06293417 ! spinal cord patterning GO:0021511 13 7 0,000 0,01959173 0,06285026 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01959173 0,06276657 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01959173 0,06268311 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01959173 0,06259986 ! adrenal gland development GO:0030325 17 7 0,000 0,01959173 0,06251684 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01959173 0,06243404 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01959173 0,06235145 ! ovulation GO:0030728 9 7 0,000 0,01959173 0,06226908 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01959173 0,06218693 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01959173 0,062105 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01959173 0,06202328 ! microtubule nucleation GO:0007020 20 7 0,000 0,01959173 0,06194178 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01959173 0,06186049 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01959173 0,06177942 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01959173 0,06169856 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01959173 0,0616179 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01959173 0,06153746 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01959173 0,06145723 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01959173 0,06137721 ! galactose metabolic process GO:0006012 13 7 0,000 0,01959173 0,06129739 ! vesicle fusion GO:0006906 17 7 0,000 0,01959173 0,06121779 ! response to dietary excess GO:0002021 8 7 0,000 0,01959173 0,06113839 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01959173 0,06105919 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01959173 0,0609802 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01959173 0,06090142 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01959173 0,06082283 ! organ growth GO:0035265 15 7 0,000 0,01959173 0,06074445 ! purine salvage GO:0043101 10 7 0,000 0,01959173 0,06066628 ! nucleoside transport GO:0015858 8 7 0,000 0,01959173 0,0605883 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01959173 0,06051052 ! parturition GO:0007567 14 7 0,000 0,01959173 0,06043294 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01959173 0,06035557 ! rRNA modification GO:0000154 14 7 0,000 0,01959173 0,06027838 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01959173 0,0602014 ! spindle checkpoint GO:0031577 15 7 0,000 0,01959173 0,06012461 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01959173 0,06004802 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01959173 0,05997162 ! macrophage differentiation GO:0030225 11 7 0,000 0,01959173 0,05989542 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01959173 0,05981941 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01959173 0,0597436 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01959173 0,05966797 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01959173 0,05959254 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01959173 0,05951729 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01959173 0,05944224 ! fibrinolysis GO:0042730 10 7 0,000 0,01959173 0,05936738 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01959173 0,0592927 ! eating behavior GO:0042755 7 7 0,000 0,01959173 0,05921821 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01959173 0,05914391 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01959173 0,0590698 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01959173 0,05899587 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01959173 0,05892212 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01959173 0,05884856 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01959173 0,05877518 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01959173 0,05870199 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01959173 0,05862898 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01959173 0,05855614 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01959173 0,05848349 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01959173 0,05841102 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01959173 0,05833873 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01959173 0,05826662 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01959173 0,05819469 ! regulation of meiosis GO:0040020 12 7 0,000 0,01959173 0,05812293 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01959173 0,05805135 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01959173 0,05797995 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01959173 0,05790872 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01959173 0,05783766 ! transcription termination GO:0006353 13 7 0,000 0,01959173 0,05776678 ! response to tumor cell GO:0002347 13 7 0,000 0,01959173 0,05769608 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01959173 0,05762555 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01959173 0,05755518 ! anaphase GO:0051322 17 7 0,000 0,01959173 0,057485 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01959173 0,05741498 ! axonal fasciculation GO:0007413 18 7 0,000 0,01959173 0,05734513 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01959173 0,05727545 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01959173 0,05720594 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01959173 0,0571366 ! diuresis GO:0030146 12 7 0,000 0,01959173 0,05706743 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01959173 0,05699842 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01959173 0,05692959 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01959173 0,05686091 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01959173 0,05679241 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01959173 0,05672406 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01959173 0,05665589 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01959173 0,05658787 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01959173 0,05652002 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01959173 0,05645233 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01959173 0,0563848 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01959173 0,05631744 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01959173 0,05625023 ! lymph node development GO:0048535 10 7 0,000 0,01959173 0,05618319 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01959173 0,05611631 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01959173 0,05604958 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01959173 0,05598301 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01959173 0,0559166 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01959173 0,05585035 ! adult feeding behavior GO:0008343 9 7 0,000 0,01959173 0,05578426 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01959173 0,05571832 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01959173 0,05565253 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01959173 0,05558691 ! muscle adaptation GO:0043500 14 7 0,000 0,01959173 0,05552143 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01959173 0,05545611 ! retina homeostasis GO:0001895 12 7 0,000 0,01959173 0,05539095 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01959173 0,05532593 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01959173 0,05526107 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01959173 0,05519637 ! protein prenylation GO:0018342 18 7 0,000 0,01959173 0,05513181 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01959173 0,0550674 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01959173 0,05500315 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01959173 0,05493904 ! regulation of catabolic process GO:0009894 161 76 1,000 0,01960101 0,0549011 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,02008731 0,05619774 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,02107497 0,05889242 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,02107497 0,0588241 ! protein import into nucleus GO:0006606 158 80 1,000 0,02157628 0,06015356 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,02208253 0,0614937 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 1,000 0,02208253 0,06142261 ! nuclear import GO:0051170 161 81 1,000 0,02208253 0,06135168 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0223594 0,06204928 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0223594 0,06197779 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0223594 0,06190647 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0223594 0,06183531 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0223594 0,06176432 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0223594 0,06169349 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0223594 0,06162282 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0223594 0,06155231 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0223594 0,06148197 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0223594 0,06141178 ! meiotic prophase I GO:0007128 13 8 0,000 0,0223594 0,06134176 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0223594 0,06127189 ! oligopeptide transport GO:0006857 15 8 0,000 0,0223594 0,06120219 ! signal peptide processing GO:0006465 12 8 0,000 0,0223594 0,06113264 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0223594 0,06106325 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0223594 0,06099402 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0223594 0,06092494 ! succinate metabolic process GO:0006105 14 8 0,000 0,0223594 0,06085602 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0223594 0,06078726 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,0223594 0,06071865 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0223594 0,0606502 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0223594 0,0605819 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0223594 0,06051375 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0223594 0,06044576 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0223594 0,06037792 ! reflex GO:0060004 16 8 0,000 0,0223594 0,06031023 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0223594 0,06024269 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0223594 0,06017531 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0223594 0,06010807 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0223594 0,06004099 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0223594 0,05997405 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0223594 0,05990726 ! pigment granule organization GO:0048753 16 8 0,000 0,0223594 0,05984063 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0223594 0,05977414 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0223594 0,05970779 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0223594 0,0596416 ! histidine metabolic process GO:0006547 16 8 0,000 0,0223594 0,05957555 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0223594 0,05950965 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0223594 0,05944389 ! glycine catabolic process GO:0006546 13 8 0,000 0,0223594 0,05937828 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0223594 0,05931282 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0223594 0,05924749 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0223594 0,05918231 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,0223594 0,05911728 ! melanin metabolic process GO:0006582 15 8 0,000 0,0223594 0,05905239 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0223594 0,05898764 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0223594 0,05892303 ! macrophage activation GO:0042116 12 8 0,000 0,0223594 0,05885856 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0223594 0,05879423 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,0223594 0,05873005 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0223594 0,058666 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0223594 0,0586021 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0223594 0,05853833 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0223594 0,0584747 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0223594 0,05841121 ! osteoblast development GO:0002076 16 8 0,000 0,0223594 0,05834786 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0223594 0,05828464 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0223594 0,05822156 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0223594 0,05815862 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0223594 0,05809581 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0223594 0,05803314 ! response to UV-B GO:0010224 16 8 0,000 0,0223594 0,05797061 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0223594 0,05790821 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0223594 0,05784594 ! intermediate filament organization GO:0045109 12 8 0,000 0,0223594 0,05778381 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0223594 0,05772181 ! cellular extravasation GO:0045123 12 8 0,000 0,0223594 0,05765994 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0223594 0,0575982 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0223594 0,0575366 ! response to antibiotic GO:0046677 11 8 0,000 0,0223594 0,05747513 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0223594 0,05741379 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0223594 0,05735258 ! DNA topological change GO:0006265 12 8 0,000 0,0223594 0,05729151 ! response to tropane GO:0014073 15 8 0,000 0,0223594 0,05723056 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0223594 0,05716974 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,0223594 0,05710905 ! melanosome transport GO:0032402 13 8 0,000 0,0223594 0,05704849 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,0223594 0,05698805 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0223594 0,05692775 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0223594 0,05686757 ! mast cell activation GO:0045576 14 8 0,000 0,0223594 0,05680752 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0223594 0,0567476 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0223594 0,0566878 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0223594 0,05662813 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0223594 0,05656858 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0223594 0,05650916 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0223594 0,05644987 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,0223594 0,0563907 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0223594 0,05633165 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0223594 0,05627272 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0223594 0,05621392 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0223594 0,05615524 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0223594 0,05609669 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0223594 0,05603825 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0223594 0,05597994 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0223594 0,05592175 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0223594 0,05586368 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0223594 0,05580573 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0223594 0,0557479 ! hormone catabolic process GO:0042447 17 8 0,000 0,0223594 0,05569019 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0223594 0,0556326 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0223594 0,05557513 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0223594 0,05551777 ! ATP catabolic process GO:0006200 11 8 0,000 0,0223594 0,05546054 ! blastocyst growth GO:0001832 19 8 0,000 0,0223594 0,05540342 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0223594 0,05534642 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0223594 0,05528954 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0223594 0,05523278 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0223594 0,05517613 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0223594 0,05511959 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0223594 0,05506318 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0223594 0,05500687 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0223594 0,05495069 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0223594 0,05489462 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0223594 0,05483866 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0223594 0,05478281 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0223594 0,05472708 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0223594 0,05467147 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0223594 0,05461596 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0223594 0,05456057 GO:0000076|DNA replication checkpoint, ! response to nutrient GO:0007584 125 82 1,000 0,02259369 0,05507641 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,02259369 0,05502066 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,02415634 0,05876658 GO:0002696|positive regulation of leukocyte activation, ! regulation of developmental growth GO:0048638 15 9 0,000 0,02511936 0,06104765 ! axon extension GO:0048675 15 9 0,000 0,02511936 0,06098605 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02511936 0,06092457 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02511936 0,06086321 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02511936 0,06080198 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02511936 0,06074088 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02511936 0,06067989 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02511936 0,06061903 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02511936 0,06055829 ! phosphate transport GO:0006817 19 9 0,000 0,02511936 0,06049767 ! reproductive behavior GO:0019098 19 9 0,000 0,02511936 0,06043717 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02511936 0,0603768 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02511936 0,06031654 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02511936 0,0602564 ! RNA methylation GO:0001510 15 9 0,000 0,02511936 0,06019639 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02511936 0,06013649 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02511936 0,06007671 ! artery development GO:0060840 24 9 0,000 0,02511936 0,06001705 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02511936 0,05995751 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02511936 0,05989809 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02511936 0,05983878 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02511936 0,0597796 ! chemosensory behavior GO:0007635 20 9 0,000 0,02511936 0,05972053 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02511936 0,05966157 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02511936 0,05960273 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02511936 0,05954401 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02511936 0,05948541 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02511936 0,05942691 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02511936 0,05936854 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02511936 0,05931028 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02511936 0,05925213 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02511936 0,0591941 ! protein targeting to ER GO:0045047 22 9 0,000 0,02511936 0,05913618 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02511936 0,05907837 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02511936 0,05902068 ! T cell selection GO:0045058 23 9 0,000 0,02511936 0,05896309 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,02511936 0,05890563 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02511936 0,05884827 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02511936 0,05879102 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02511936 0,05873389 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02511936 0,05867687 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02511936 0,05861995 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02511936 0,05856315 ! mannose metabolic process GO:0006013 13 9 0,000 0,02511936 0,05850646 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02511936 0,05844988 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02511936 0,0583934 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02511936 0,05833704 ! receptor clustering GO:0043113 18 9 0,000 0,02511936 0,05828078 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02511936 0,05822464 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02511936 0,0581686 ! ruffle organization GO:0031529 15 9 0,000 0,02511936 0,05811267 ! retinol metabolic process GO:0042572 18 9 0,000 0,02511936 0,05805684 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02511936 0,05800113 ! behavioral fear response GO:0001662 22 9 0,000 0,02511936 0,05794552 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02511936 0,05789001 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02511936 0,05783461 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02511936 0,05777932 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,02511936 0,05772414 ! protein heterooligomerization GO:0051291 16 9 0,000 0,02511936 0,05766906 ! oligodendrocyte development GO:0014003 10 9 0,000 0,02511936 0,05761408 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02511936 0,05755921 ! segment specification GO:0007379 13 9 0,000 0,02511936 0,05750445 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02511936 0,05744978 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02511936 0,05739523 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02511936 0,05734077 ! response to amine stimulus GO:0014075 13 9 0,000 0,02511936 0,05728642 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02511936 0,05723217 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02511936 0,05717802 ! erythrocyte development GO:0048821 15 9 0,000 0,02511936 0,05712398 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02511936 0,05707004 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02511936 0,0570162 ! renal water homeostasis GO:0003091 14 9 0,000 0,02511936 0,05696246 ! postreplication repair GO:0006301 22 9 0,000 0,02511936 0,05690883 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02511936 0,05685529 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02511936 0,05680185 ! icosanoid secretion GO:0032309 15 9 0,000 0,02511936 0,05674852 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02511936 0,05669528 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02511936 0,05664215 ! regulation of cell division GO:0051302 15 9 0,000 0,02511936 0,05658911 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02511936 0,05653618 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02511936 0,05648334 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02511936 0,0564306 ! sterol catabolic process GO:0016127 11 9 0,000 0,02511936 0,05637796 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02511936 0,05632542 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02511936 0,05627297 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02511936 0,05622063 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02511936 0,05616838 GO:0000084|S phase of mitotic cell cycle, ! musculoskeletal movement GO:0050881 14 9 0,000 0,02511936 0,05611622 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02511936 0,05606417 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02511936 0,05601221 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02511936 0,05596034 ! purine base metabolic process GO:0006144 21 9 0,000 0,02511936 0,05590858 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02511936 0,05585691 ! pigment granule transport GO:0051904 17 9 0,000 0,02511936 0,05580533 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02511936 0,05575385 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02511936 0,05570246 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02511936 0,05565117 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02511936 0,05559997 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02511936 0,05554887 ! mitochondrion localization GO:0051646 15 9 0,000 0,02511936 0,05549786 ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,0252221 0,05567373 ! protein localization in nucleus GO:0034504 176 87 1,000 0,0252221 0,0556227 ! regulation of protein transport GO:0051223 154 87 1,000 0,0252221 0,05557176 GO:0070201|regulation of establishment of protein localization, ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,02630676 0,05790857 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02787161 0,06129716 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02787161 0,06124118 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02787161 0,06118531 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02787161 0,06112953 ! synapsis GO:0007129 13 10 0,000 0,02787161 0,06107386 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02787161 0,06101828 ! N-glycan processing GO:0006491 20 10 0,000 0,02787161 0,06096281 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02787161 0,06090744 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02787161 0,06085217 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02787161 0,060797 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02787161 0,06074193 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02787161 0,06068696 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02787161 0,06063209 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02787161 0,06057732 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02787161 0,06052265 ! androgen metabolic process GO:0008209 17 10 0,000 0,02787161 0,06046807 ! phospholipid efflux GO:0033700 16 10 0,000 0,02787161 0,0604136 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02787161 0,06035922 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02787161 0,06030494 ! pathogenesis GO:0009405 13 10 0,000 0,02787161 0,06025076 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02787161 0,06019667 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02787161 0,06014269 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02787161 0,06008879 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02787161 0,060035 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02787161 0,0599813 ! endoderm development GO:0007492 16 10 0,000 0,02787161 0,0599277 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02787161 0,05987419 ! arginine catabolic process GO:0006527 13 10 0,000 0,02787161 0,05982078 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02787161 0,05976746 ! proline metabolic process GO:0006560 13 10 0,000 0,02787161 0,05971424 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02787161 0,05966112 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02787161 0,05960808 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02787161 0,05955515 ! V(D)J recombination GO:0033151 28 10 0,000 0,02787161 0,0595023 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02787161 0,05944955 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02787161 0,0593969 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02787161 0,05934433 ! B cell proliferation GO:0042100 18 10 0,000 0,02787161 0,05929186 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02787161 0,05923948 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02787161 0,0591872 ! multicellular organism growth GO:0035264 18 10 0,000 0,02787161 0,059135 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02787161 0,0590829 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02787161 0,05903089 ! epithelial cell development GO:0002064 20 10 0,000 0,02787161 0,05897898 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02787161 0,05892715 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02787161 0,05887541 ! macroautophagy GO:0016236 17 10 0,000 0,02787161 0,05882377 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02787161 0,05877221 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02787161 0,05872075 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02787161 0,05866937 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02787161 0,05861809 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02787161 0,05856689 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02787161 0,05851579 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02787161 0,05846477 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02787161 0,05841385 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02787161 0,05836301 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02787161 0,05831226 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02787161 0,05826159 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02787161 0,05821102 ! response to dsRNA GO:0043331 20 10 0,000 0,02787161 0,05816053 ! DNA ligation GO:0006266 19 10 0,000 0,02787161 0,05811013 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02787161 0,05805982 ! melanosome localization GO:0032400 16 10 0,000 0,02787161 0,0580096 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02787161 0,05795946 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02787161 0,05790941 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02787161 0,05785944 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02787161 0,05780956 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02787161 0,05775977 ! mRNA cleavage GO:0006379 17 10 0,000 0,02787161 0,05771006 ! protein sumoylation GO:0016925 15 10 0,000 0,02787161 0,05766044 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02787161 0,05761091 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02787161 0,05756145 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02787161 0,05751209 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02787161 0,05746281 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02787161 0,05741361 ! salivary gland development GO:0007431 27 10 0,000 0,02787161 0,0573645 ! prophase GO:0051324 15 10 0,000 0,02787161 0,05731547 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02787161 0,05726652 ! apical protein localization GO:0045176 15 10 0,000 0,02787161 0,05721766 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02787161 0,05716888 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02787161 0,05712018 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02787161 0,05707157 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02787161 0,05702304 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02787161 0,05697459 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02787161 0,05692623 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02787161 0,05687794 ! detection of calcium ion GO:0005513 23 10 0,000 0,02787161 0,05682974 ! oocyte development GO:0048599 17 10 0,000 0,02787161 0,05678162 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02787161 0,05673358 ! blastocyst formation GO:0001825 17 10 0,000 0,02787161 0,05668563 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02787161 0,05663775 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02787161 0,05658995 ! activation of innate immune response GO:0002218 12 10 0,000 0,02787161 0,05654224 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02787161 0,0564946 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02787161 0,05644705 ! response to nicotine GO:0035094 20 10 0,000 0,02787161 0,05639958 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02787161 0,05635218 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02787161 0,05630487 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,02853186 0,05759032 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,02853186 0,05754204 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,02909958 0,05863785 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,02967182 0,05974091 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03061619 0,06159075 ! respiratory burst GO:0045730 17 11 0,000 0,03061619 0,0615393 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03061619 0,06148793 ! neuron fate specification GO:0048665 17 11 0,000 0,03061619 0,06143665 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03061619 0,06138545 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03061619 0,06133434 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03061619 0,06128331 ! thyroid gland development GO:0030878 26 11 0,000 0,03061619 0,06123237 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03061619 0,06118151 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03061619 0,06113074 ! response to pain GO:0048265 24 11 0,000 0,03061619 0,06108005 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03061619 0,06102945 ! T cell proliferation GO:0042098 26 11 0,000 0,03061619 0,06097893 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03061619 0,06092849 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,03061619 0,06087813 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03061619 0,06082786 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03061619 0,06077767 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03061619 0,06072757 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03061619 0,06067755 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03061619 0,06062761 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03061619 0,06057775 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03061619 0,06052797 GO:0010833|telomere maintenance via telomere lengthening, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03061619 0,06047828 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,03061619 0,06042866 ! lipid digestion GO:0044241 18 11 0,000 0,03061619 0,06037913 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03061619 0,06032968 ! UV protection GO:0009650 19 11 0,000 0,03061619 0,06028031 ! adult heart development GO:0007512 14 11 0,000 0,03061619 0,06023102 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03061619 0,06018182 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03061619 0,06013269 ! temperature homeostasis GO:0001659 17 11 0,000 0,03061619 0,06008364 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03061619 0,06003467 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03061619 0,05998578 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03061619 0,05993697 ! regulation of organ growth GO:0046620 13 11 0,000 0,03061619 0,05988825 ! pigment granule localization GO:0051875 20 11 0,000 0,03061619 0,0598396 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03061619 0,05979102 ! vasoconstriction GO:0042310 18 11 0,000 0,03061619 0,05974253 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03061619 0,05969412 ! embryonic axis specification GO:0000578 18 11 0,000 0,03061619 0,05964578 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03061619 0,05959753 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03061619 0,05954935 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03061619 0,05950125 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03061619 0,05945322 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03061619 0,05940528 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03061619 0,05935741 ! zymogen activation GO:0031638 15 11 0,000 0,03061619 0,05930961 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03061619 0,0592619 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03061619 0,05921426 ! nucleosome positioning GO:0016584 15 11 0,000 0,03061619 0,0591667 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03061619 0,05911921 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03061619 0,05907181 ! acid secretion GO:0046717 18 11 0,000 0,03061619 0,05902447 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03061619 0,05897722 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03061619 0,05893003 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03061619 0,05888293 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03061619 0,0588359 ! oocyte differentiation GO:0009994 18 11 0,000 0,03061619 0,05878894 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03061619 0,05874206 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03061619 0,05869525 ! cholesterol efflux GO:0033344 19 11 0,000 0,03061619 0,05864852 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03061619 0,05860186 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03061619 0,05855528 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03061619 0,05850877 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03061619 0,05846233 ! embryonic gut development GO:0048566 15 11 0,000 0,03061619 0,05841597 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03061619 0,05836968 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03061619 0,05832347 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03061619 0,05827733 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03061619 0,05823126 ! defense response to fungus GO:0050832 13 11 0,000 0,03061619 0,05818526 ! lysogeny GO:0030069 21 11 0,000 0,03061619 0,05813934 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03061619 0,05809349 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03061619 0,05804771 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03061619 0,058002 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03061619 0,05795637 ! regulation of embryonic development GO:0045995 27 11 0,000 0,03061619 0,0579108 ! nucleus localization GO:0051647 19 11 0,000 0,03061619 0,05786531 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03061619 0,05781989 ! protein ubiquitination GO:0016567 217 97 1,000 0,03082973 0,0581775 ! regulation of protein localization GO:0032880 176 97 1,000 0,03082973 0,05813191 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,03141534 0,05918975 GO:0016054|organic acid catabolic process, ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,0333531 0,06279152 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,0333531 0,06274243 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,0333531 0,06269341 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,0333531 0,06264447 ! virus-host interaction GO:0019048 29 12 0,000 0,0333531 0,0625956 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,0333531 0,06254682 ! mating GO:0007618 17 12 0,000 0,0333531 0,0624981 ! protein complex disassembly GO:0043241 27 12 0,000 0,0333531 0,06244947 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0333531 0,06240091 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,0333531 0,06235242 ! hippocampus development GO:0021766 26 12 0,000 0,0333531 0,06230401 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,0333531 0,06225567 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,0333531 0,06220741 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0333531 0,06215923 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,0333531 0,06211112 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,0333531 0,06206308 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,0333531 0,06201512 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,0333531 0,06196723 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,0333531 0,06191942 ! drug transport GO:0015893 16 12 0,000 0,0333531 0,06187168 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,0333531 0,06182401 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,0333531 0,06177642 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,0333531 0,0617289 ! polyamine metabolic process GO:0006595 17 12 0,000 0,0333531 0,06168145 ! focal adhesion formation GO:0048041 35 12 0,000 0,0333531 0,06163407 ! mitotic spindle organization GO:0007052 21 12 0,000 0,0333531 0,06158677 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,0333531 0,06153954 ! forebrain cell migration GO:0021885 21 12 0,000 0,0333531 0,06149239 ! asymmetric protein localization GO:0008105 20 12 0,000 0,0333531 0,0614453 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,0333531 0,06139829 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,0333531 0,06135135 ! entry into host cell GO:0030260 32 12 0,000 0,0333531 0,06130448 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,0333531 0,06125768 ! monoamine transport GO:0015844 18 12 0,000 0,0333531 0,06121096 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0333531 0,0611643 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,0333531 0,06111772 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,0333531 0,06107121 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,0333531 0,06102476 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0333531 0,06097839 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,0333531 0,06093209 ! protein homotetramerization GO:0051289 21 12 0,000 0,0333531 0,06088586 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,0333531 0,0608397 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,0333531 0,06079361 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,0333531 0,06074759 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,0333531 0,06070164 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0333531 0,06065576 ! cranial nerve development GO:0021545 20 12 0,000 0,0333531 0,06060994 ! fucose catabolic process GO:0019317 22 12 0,000 0,0333531 0,0605642 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,0333531 0,06051852 ! histone methylation GO:0016571 26 12 0,000 0,0333531 0,06047292 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,0333531 0,06042738 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0333531 0,06038191 ! gland morphogenesis GO:0022612 29 12 0,000 0,0333531 0,06033651 ! T cell homeostasis GO:0043029 25 12 0,000 0,0333531 0,06029118 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,0333531 0,06024592 ! spleen development GO:0048536 22 12 0,000 0,0333531 0,06020072 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,0333531 0,0601556 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,0333531 0,06011053 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,0333531 0,06006554 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,0333531 0,06002062 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,0333531 0,05997576 ! response to cold GO:0009409 17 12 0,000 0,0333531 0,05993097 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,0333531 0,05988624 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,0333531 0,05984158 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03608238 0,06469017 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03608238 0,064642 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03608238 0,06459391 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,03608238 0,06454588 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03608238 0,06449793 ! lipid localization GO:0010876 28 13 0,000 0,03608238 0,06445005 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03608238 0,06440223 ! organelle fusion GO:0048284 32 13 0,000 0,03608238 0,06435449 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03608238 0,06430682 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03608238 0,06425922 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03608238 0,0642117 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03608238 0,06416424 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03608238 0,06411685 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03608238 0,06406953 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03608238 0,06402228 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03608238 0,0639751 ! methionine metabolic process GO:0006555 27 13 0,000 0,03608238 0,06392799 ! plasma membrane organization GO:0007009 24 13 0,000 0,03608238 0,06388095 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03608238 0,06383398 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03608238 0,06378708 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03608238 0,06374024 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03608238 0,06369348 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,03608238 0,06364678 ! response to X-ray GO:0010165 25 13 0,000 0,03608238 0,06360016 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03608238 0,0635536 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,03608238 0,06350711 ! exocrine system development GO:0035272 32 13 0,000 0,03608238 0,06346068 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03608238 0,06341433 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03608238 0,06336804 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03608238 0,06332182 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03608238 0,06327567 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03608238 0,06322958 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03608238 0,06318356 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03608238 0,06313761 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03608238 0,06309172 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03608238 0,06304591 ! regulation of cellular pH GO:0030641 22 13 0,000 0,03608238 0,06300015 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03608238 0,06295447 ! ribosome assembly GO:0042255 17 13 0,000 0,03608238 0,06290885 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03608238 0,0628633 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03608238 0,06281781 ! chromatin silencing GO:0006342 26 13 0,000 0,03608238 0,06277239 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03608238 0,06272703 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03608238 0,06268174 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03608238 0,06263652 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03608238 0,06259136 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03608238 0,06254626 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03608238 0,06250123 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03608238 0,06245627 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,03608238 0,06241137 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03608238 0,06236653 ! insulin secretion GO:0030073 23 13 0,000 0,03608238 0,06232176 ! actin filament polymerization GO:0030041 24 13 0,000 0,03608238 0,06227705 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,03608238 0,06223241 ! acrosome reaction GO:0007340 18 13 0,000 0,03608238 0,06218783 ! rRNA transcription GO:0009303 25 14 0,000 0,03880405 0,06683074 ! lactation GO:0007595 26 14 0,000 0,03880405 0,06678293 ! reproductive cellular process GO:0048610 20 14 0,000 0,03880405 0,0667352 ! tRNA modification GO:0006400 20 14 0,000 0,03880405 0,06668753 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03880405 0,06663993 ! regulation of S phase GO:0033261 23 14 0,000 0,03880405 0,0665924 ! water transport GO:0006833 21 14 0,000 0,03880405 0,06654493 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03880405 0,06649753 ! non-recombinational repair GO:0000726 25 14 0,000 0,03880405 0,06645021 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03880405 0,06640294 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03880405 0,06635575 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03880405 0,06630862 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03880405 0,06626156 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03880405 0,06621457 ! palate development GO:0060021 31 14 0,000 0,03880405 0,06616764 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03880405 0,06612078 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03880405 0,06607398 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03880405 0,06602725 ! arginine metabolic process GO:0006525 17 14 0,000 0,03880405 0,06598059 ! regulation of heart rate GO:0002027 24 14 0,000 0,03880405 0,065934 ! organic alcohol transport GO:0015850 29 14 0,000 0,03880405 0,06588747 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,03880405 0,065841 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03880405 0,0657946 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03880405 0,06574827 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03880405 0,065702 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03880405 0,06565579 ! L-amino acid transport GO:0015807 30 14 0,000 0,03880405 0,06560965 ! bone mineralization GO:0030282 17 14 0,000 0,03880405 0,06556358 ! stem cell development GO:0048864 43 14 0,000 0,03880405 0,06551757 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03880405 0,06547163 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03880405 0,06542575 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03880405 0,06537993 ! cerebellum development GO:0021549 21 14 0,000 0,03880405 0,06533418 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03880405 0,06528849 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03880405 0,06524286 ! response to gamma radiation GO:0010332 28 14 0,000 0,03880405 0,0651973 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03880405 0,06515181 ! cofactor transport GO:0051181 26 14 0,000 0,03880405 0,06510637 ! NADP metabolic process GO:0006739 24 14 0,000 0,03880405 0,065061 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03880405 0,0650157 ! intestinal absorption GO:0050892 25 14 0,000 0,03880405 0,06497045 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03880405 0,06492527 ! oxygen transport GO:0015671 21 14 0,000 0,03880405 0,06488015 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03880405 0,0648351 ! male genitalia development GO:0030539 24 14 0,000 0,03880405 0,0647901 ! regulation of axon extension GO:0030516 37 14 0,000 0,03880405 0,06474517 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,03880405 0,0647003 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03880405 0,0646555 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04151812 0,06912982 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04151812 0,06908201 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,04151812 0,06903427 ! superoxide anion generation GO:0042554 20 15 0,000 0,04151812 0,0689866 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04151812 0,06893899 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04151812 0,06889144 ! copper ion transport GO:0006825 20 15 0,000 0,04151812 0,06884396 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04151812 0,06879655 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04151812 0,0687492 ! sulfate transport GO:0008272 23 15 0,000 0,04151812 0,06870192 ! response to cAMP GO:0051591 22 15 0,000 0,04151812 0,0686547 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04151812 0,06860755 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04151812 0,06856046 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04151812 0,06851344 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04151812 0,06846648 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04151812 0,06841958 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04151812 0,06837275 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04151812 0,06832599 ! pituitary gland development GO:0021983 29 15 0,000 0,04151812 0,06827928 ! vesicle coating GO:0006901 33 15 0,000 0,04151812 0,06823264 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,04151812 0,06818607 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04151812 0,06813956 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,04151812 0,06809311 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04151812 0,06804672 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,04151812 0,0680004 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04151812 0,06795414 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04151812 0,06790795 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04151812 0,06786181 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04151812 0,06781574 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04151812 0,06776974 ! histone deacetylation GO:0016575 20 15 0,000 0,04151812 0,06772379 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04151812 0,06767791 ! tissue regeneration GO:0042246 26 15 0,000 0,04151812 0,06763209 ! water homeostasis GO:0030104 27 15 0,000 0,04151812 0,06758633 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04151812 0,06754063 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04151812 0,06749499 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04151812 0,06744942 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04151812 0,06740391 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04151812 0,06735846 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04151812 0,06731307 ! cell killing GO:0001906 29 15 0,000 0,04151812 0,06726774 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04151812 0,06722247 ! detection of bacterium GO:0016045 18 15 0,000 0,04151812 0,06717726 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04151812 0,06713212 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04151812 0,06708703 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04151812 0,06704201 ! peptide hormone processing GO:0016486 23 15 0,000 0,04151812 0,06699704 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04422461 0,07131664 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,04422461 0,07126887 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04422461 0,07122117 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04422461 0,07117353 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04422461 0,07112595 ! bone remodeling GO:0046849 27 16 0,000 0,04422461 0,07107844 ! filopodium assembly GO:0046847 32 16 0,000 0,04422461 0,07103099 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,04422461 0,0709836 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04422461 0,07093628 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04422461 0,07088902 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04422461 0,07084183 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04422461 0,07079469 ! startle response GO:0001964 28 16 0,000 0,04422461 0,07074762 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04422461 0,07070061 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04422461 0,07065367 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04422461 0,07060678 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,04422461 0,07055996 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04422461 0,0705132 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04422461 0,0704665 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04422461 0,07041987 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04422461 0,07037329 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04422461 0,07032678 ! response to osmotic stress GO:0006970 25 16 0,000 0,04422461 0,07028033 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,04422461 0,07023394 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,04422461 0,07018761 ! fructose metabolic process GO:0006000 25 16 0,000 0,04422461 0,07014135 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04422461 0,07009514 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04422461 0,07004899 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04422461 0,07000291 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04422461 0,06995688 ! axon cargo transport GO:0008088 43 16 0,000 0,04422461 0,06991092 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04422461 0,06986502 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04422461 0,06981917 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,04422461 0,06977339 ! DNA replication initiation GO:0006270 27 16 0,000 0,04422461 0,06972767 ! neuron recognition GO:0008038 35 16 0,000 0,04422461 0,06968201 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04422461 0,0696364 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04422461 0,06959086 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04422461 0,06954537 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04422461 0,06949995 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04422461 0,06945458 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04422461 0,06940928 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04422461 0,06936403 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04422461 0,06931884 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04422461 0,06927371 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,04422461 0,06922864 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04422461 0,06918363 ! defense response to virus GO:0051607 37 16 0,000 0,04422461 0,06913868 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,04692356 0,07331044 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,04692356 0,07326287 ! metencephalon development GO:0022037 30 17 0,000 0,04692356 0,07321536 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,04692356 0,07316791 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,04692356 0,07312052 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,04692356 0,07307319 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,04692356 0,07302593 ! signal complex assembly GO:0007172 41 17 0,000 0,04692356 0,07297872 ! endothelial cell migration GO:0043542 28 17 0,000 0,04692356 0,07293158 ! inositol metabolic process GO:0006020 28 17 0,000 0,04692356 0,07288449 ! gene silencing by RNA GO:0031047 36 17 0,000 0,04692356 0,07283747 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,04692356 0,07279051 ! glial cell development GO:0021782 27 17 0,000 0,04692356 0,07274361 ! limbic system development GO:0021761 36 17 0,000 0,04692356 0,07269677 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,04692356 0,07264999 ! adult walking behavior GO:0007628 33 17 0,000 0,04692356 0,07260327 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,04692356 0,07255661 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,04692356 0,07251001 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,04692356 0,07246347 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,04692356 0,07241699 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,04692356 0,07237056 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,04692356 0,0723242 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,04692356 0,0722779 ! glycine metabolic process GO:0006544 28 17 0,000 0,04692356 0,07223166 ! membrane budding GO:0006900 37 17 0,000 0,04692356 0,07218547 ! DNA integration GO:0015074 29 17 0,000 0,04692356 0,07213935 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,04692356 0,07209328 ! regulation of protein binding GO:0043393 33 17 0,000 0,04692356 0,07204728 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,04692356 0,07200133 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,04692356 0,07195544 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,04692356 0,07190961 ! genitalia development GO:0048806 30 17 0,000 0,04692356 0,07186383 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,04692356 0,07181812 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,04692356 0,07177246 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,04692356 0,07172686 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,04692356 0,07168132 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,04692356 0,07163584 ! steroid catabolic process GO:0006706 31 17 0,000 0,04692356 0,07159041 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,04692356 0,07154504 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,04692356 0,07149973 ! gas transport GO:0015669 25 17 0,000 0,04692356 0,07145448 ! organic cation transport GO:0015695 31 17 0,000 0,04692356 0,07140929 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,04692356 0,07136415 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,04692356 0,07131907 ! microspike assembly GO:0030035 36 17 0,000 0,04692356 0,07127404 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,04692356 0,07122907 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,04692356 0,07118416 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,04961497 0,07521967 ! neuron maturation GO:0042551 42 18 0,000 0,04961497 0,0751723 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,04961497 0,075125 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,04961497 0,07507775 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,04961497 0,07503056 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,04961497 0,07498343 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,04961497 0,07493636 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,04961497 0,07488935 ! memory GO:0007613 31 18 0,000 0,04961497 0,07484239 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04961497 0,0747955 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,04961497 0,07474866 ! patterning of blood vessels GO:0001569 39 18 0,000 0,04961497 0,07470189 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,04961497 0,07465517 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,04961497 0,07460851 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,04961497 0,07456191 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04961497 0,07451537 ! response to retinoic acid GO:0032526 26 18 0,000 0,04961497 0,07446888 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,04961497 0,07442245 ! response to fungus GO:0009620 21 18 0,000 0,04961497 0,07437609 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,04961497 0,07432977 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,04961497 0,07428352 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,04961497 0,07423732 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,04961497 0,07419119 ! vitamin transport GO:0051180 27 18 0,000 0,04961497 0,0741451 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,04961497 0,07409908 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,04961497 0,07405311 GO:0033014|tetrapyrrole biosynthetic process, ! nerve development GO:0021675 28 18 0,000 0,04961497 0,0740072 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,04961497 0,07396135 ! protein secretion GO:0009306 39 19 0,000 0,05229887 0,07791398 ! positive regulation of translation GO:0045727 30 19 0,000 0,05229887 0,07786577 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05229887 0,07781761 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,05229887 0,07776952 ! skin development GO:0043588 36 19 0,000 0,05229887 0,07772148 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05229887 0,07767351 ! lipid phosphorylation GO:0046834 35 19 0,000 0,05229887 0,07762559 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05229887 0,07757773 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,05229887 0,07752993 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05229887 0,07748219 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05229887 0,07743451 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,05229887 0,07738689 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,05229887 0,07733933 ! cerebral cortex development GO:0021987 36 19 0,000 0,05229887 0,07729182 ! pigmentation during development GO:0048066 41 19 0,000 0,05229887 0,07724437 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,05229887 0,07719698 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,05229887 0,07714965 ! heme metabolic process GO:0042168 36 19 0,000 0,05229887 0,07710238 ! actin filament bundle formation GO:0051017 42 19 0,000 0,05229887 0,07705516 ! neuromuscular junction development GO:0007528 34 19 0,000 0,05229887 0,07700801 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05229887 0,07696091 ! plasma membrane fusion GO:0045026 28 19 0,000 0,05229887 0,07691386 ! protein export from nucleus GO:0006611 36 19 0,000 0,05229887 0,07686688 ! heart process GO:0003015 30 19 0,000 0,05229887 0,07681995 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05229887 0,07677308 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,05229887 0,07672627 ! visual learning GO:0008542 36 19 0,000 0,05229887 0,07667951 ! cellular pigmentation GO:0033059 36 19 0,000 0,05229887 0,07663282 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05229887 0,07658617 ! cell-cell junction organization GO:0045216 35 19 0,000 0,05229887 0,07653959 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05229887 0,07649306 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05229887 0,07644659 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05229887 0,07640017 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05229887 0,07635381 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,05229887 0,07630751 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05229887 0,07626126 ! cilium assembly GO:0042384 37 19 0,000 0,05229887 0,07621507 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05229887 0,07616894 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,05497528 0,08001847 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,05497528 0,07997009 ! positive regulation of ossification GO:0045778 47 20 0,000 0,05497528 0,07992177 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,05497528 0,07987351 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,05497528 0,0798253 ! cAMP metabolic process GO:0046058 36 20 0,000 0,05497528 0,07977716 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,05497528 0,07972907 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,05497528 0,07968104 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,05497528 0,07963307 ! response to alkaloid GO:0043279 38 20 0,000 0,05497528 0,07958515 ! retinoid metabolic process GO:0001523 32 20 0,000 0,05497528 0,0795373 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,05497528 0,0794895 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,05497528 0,07944176 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,05497528 0,07939407 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,05497528 0,07934645 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,05497528 0,07929888 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,05497528 0,07925136 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,05497528 0,07920391 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,05497528 0,07915651 ! body fluid secretion GO:0007589 31 20 0,000 0,05497528 0,07910917 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,05497528 0,07906188 ! peptide secretion GO:0002790 35 20 0,000 0,05497528 0,07901465 ! stem cell differentiation GO:0048863 53 20 0,000 0,05497528 0,07896748 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,05497528 0,07892036 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,05497528 0,0788733 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,05497528 0,0788263 ! sensory perception of pain GO:0019233 30 20 0,000 0,05497528 0,07877935 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,05497528 0,07873246 ! diencephalon development GO:0021536 34 20 0,000 0,05497528 0,07868562 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,05497528 0,07863884 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,05497528 0,07859211 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,05497528 0,07854544 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,05497528 0,07849883 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,05497528 0,07845227 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,05497528 0,07840577 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,05497528 0,07835932 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,05497528 0,07831292 ! regulation of glucose import GO:0046324 29 20 0,000 0,05497528 0,07826658 GO:0010827|regulation of glucose transport, ! actin filament-based movement GO:0030048 43 20 0,000 0,05497528 0,0782203 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,05497528 0,07817407 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,05497528 0,07812789 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,05497528 0,07808177 ! negative regulation of translation GO:0017148 29 20 0,000 0,05497528 0,07803571 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,05497528 0,0779897 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,05497528 0,07794374 ! regulation of cell killing GO:0031341 42 21 0,000 0,05764422 0,08167962 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,05764422 0,08163155 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,05764422 0,08158353 ! hormone secretion GO:0046879 38 21 0,000 0,05764422 0,08153557 ! glycerol metabolic process GO:0006071 34 21 0,000 0,05764422 0,08148766 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,05764422 0,08143981 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,05764422 0,08139202 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,05764422 0,08134428 ! axis specification GO:0009798 38 21 0,000 0,05764422 0,0812966 ! ovarian follicle development GO:0001541 35 21 0,000 0,05764422 0,08124897 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,05764422 0,0812014 ! smooth muscle contraction GO:0006939 46 21 0,000 0,05764422 0,08115389 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,05764422 0,08110643 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,05764422 0,08105903 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,05764422 0,08101168 ! cell aging GO:0007569 44 21 0,000 0,05764422 0,08096439 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,05764422 0,08091715 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,05764422 0,08086997 ! cytolysis GO:0019835 24 21 0,000 0,05764422 0,08082284 ! vasodilation GO:0042311 39 21 0,000 0,05764422 0,08077577 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,05764422 0,08072875 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,05764422 0,08068179 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,05764422 0,08063488 ! oogenesis GO:0048477 36 21 0,000 0,05764422 0,08058803 ! DNA modification GO:0006304 34 21 0,000 0,05764422 0,08054123 ! collagen fibril organization GO:0030199 59 21 0,000 0,05764422 0,08049448 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,05764422 0,08044779 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,05764422 0,08040116 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,05764422 0,08035458 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,05764422 0,08030805 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,05764422 0,08026157 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,05764422 0,08021515 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,05764422 0,08016878 ! collagen catabolic process GO:0030574 28 21 0,000 0,05764422 0,08012247 ! sperm-egg recognition GO:0035036 21 21 0,000 0,05764422 0,08007621 ! gut development GO:0048565 39 21 0,000 0,05764422 0,08003 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,06030571 0,08367678 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,06030571 0,08362856 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06030571 0,08358038 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06030571 0,08353227 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06030571 0,0834842 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,06030571 0,0834362 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06030571 0,08338824 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,06030571 0,08334035 ! regeneration GO:0031099 41 22 0,000 0,06030571 0,08329251 ! keratinization GO:0031424 28 22 0,000 0,06030571 0,08324472 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,06030571 0,08319699 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,06030571 0,08314931 ! sensory perception of taste GO:0050909 28 22 0,000 0,06030571 0,08310169 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,06030571 0,08305412 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06030571 0,0830066 ! vacuolar transport GO:0007034 36 22 0,000 0,06030571 0,08295915 ! lysosome organization GO:0007040 41 22 0,000 0,06030571 0,08291174 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06030571 0,08286439 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,06030571 0,08281709 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,06030571 0,08276985 ! fucose metabolic process GO:0006004 39 22 0,000 0,06030571 0,08272266 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,06030571 0,08267552 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,06030571 0,08262844 ! ureteric bud development GO:0001657 43 22 0,000 0,06030571 0,08258141 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06030571 0,08253444 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06030571 0,08248752 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,06030571 0,08244065 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,06030571 0,08239384 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06030571 0,08234707 ! sarcomere organization GO:0045214 30 22 0,000 0,06030571 0,08230037 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,06030571 0,08225371 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,06030571 0,08220711 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,06030571 0,08216056 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,06030571 0,08211406 ! protein stabilization GO:0050821 39 22 0,000 0,06030571 0,08206762 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,06295978 0,08563099 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,06295978 0,08558261 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,06295978 0,08553429 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,06295978 0,08548602 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,06295978 0,0854378 ! gluconeogenesis GO:0006094 33 23 0,000 0,06295978 0,08538964 ! viral genome replication GO:0019079 41 23 0,000 0,06295978 0,08534153 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,06295978 0,08529348 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,06295978 0,08524548 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,06295978 0,08519754 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,06295978 0,08514965 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,06295978 0,08510181 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,06295978 0,08505403 ! visual behavior GO:0007632 42 23 0,000 0,06295978 0,0850063 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,06295978 0,08495862 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,06295978 0,084911 ! response to ethanol GO:0045471 46 23 0,000 0,06295978 0,08486343 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,06295978 0,08481591 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,06295978 0,08476845 ! peroxisome organization GO:0007031 37 23 0,000 0,06295978 0,08472104 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,06295978 0,08467368 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,06295978 0,08462638 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,06295978 0,08457913 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,06295978 0,08453193 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,06295978 0,08448478 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,06295978 0,08443769 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,06295978 0,08439065 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,06295978 0,08434366 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,06295978 0,08429673 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,06295978 0,08424984 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,06295978 0,08420301 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,06295978 0,08415623 ! fatty acid transport GO:0015908 44 23 0,000 0,06295978 0,08410951 ! platelet activation GO:0030168 37 23 0,000 0,06295978 0,08406283 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,06295978 0,08401621 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,06295978 0,08396963 ! hormone transport GO:0009914 40 23 0,000 0,06295978 0,08392311 ! cell-cell recognition GO:0009988 25 23 0,000 0,06295978 0,08387664 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,06295978 0,08383023 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,06295978 0,08378386 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,06295978 0,08373755 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,06295978 0,08369128 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,06560643 0,08716128 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,06560643 0,08711317 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,06560643 0,08706512 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,06560643 0,08701713 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,06560643 0,08696918 ! vesicle docking GO:0048278 47 24 0,000 0,06560643 0,08692129 ! spinal cord development GO:0021510 47 24 0,000 0,06560643 0,08687346 ! vacuole organization GO:0007033 43 24 0,000 0,06560643 0,08682567 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,06560643 0,08677794 ! digestive system process GO:0022600 39 24 0,000 0,06560643 0,08673026 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,06560643 0,08668263 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,06560643 0,08663505 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,06560643 0,08658753 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,06560643 0,08654006 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,06560643 0,08649264 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,06560643 0,08644527 ! membrane depolarization GO:0051899 39 24 0,000 0,06560643 0,08639796 ! pallium development GO:0021543 49 24 0,000 0,06560643 0,08635069 ! pentose metabolic process GO:0019321 35 24 0,000 0,06560643 0,08630348 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,06560643 0,08625632 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,06560643 0,08620921 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,06560643 0,08616216 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,06560643 0,08611515 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,06560643 0,0860682 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,06560643 0,08602129 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,06560643 0,08597444 ! regulation of amine transport GO:0051952 40 24 0,000 0,06560643 0,08592764 ! protein tetramerization GO:0051262 52 24 0,000 0,06560643 0,08588089 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,0682457 0,08928719 ! myelination GO:0042552 45 25 0,000 0,0682457 0,08923867 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,0682457 0,08919019 ! phototransduction GO:0007602 33 25 0,000 0,0682457 0,08914177 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,0682457 0,08909341 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,0682457 0,08904509 ! sperm motility GO:0030317 31 25 0,000 0,0682457 0,08899683 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,0682457 0,08894862 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,0682457 0,08890046 ! receptor metabolic process GO:0043112 46 25 0,000 0,0682457 0,08885235 ! chromosome condensation GO:0030261 45 25 0,000 0,0682457 0,0888043 ! response to starvation GO:0042594 42 25 0,000 0,0682457 0,08875629 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,0682457 0,08870834 ! negative regulation of cell development GO:0010721 73 25 0,000 0,0682457 0,08866045 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,0682457 0,0886126 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,0682457 0,0885648 ! interaction with host GO:0051701 62 25 0,000 0,0682457 0,08851706 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,0682457 0,08846937 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,0682457 0,08842173 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,0682457 0,08837414 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,0682457 0,0883266 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,0682457 0,08827911 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,0682457 0,08823167 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,0682457 0,08818429 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,0682457 0,08813695 ! telomere organization GO:0032200 43 25 0,000 0,0682457 0,08808967 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,0682457 0,08804244 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,0682457 0,08799525 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,0708776 0,09133985 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,0708776 0,09129095 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,0708776 0,09124211 ! initiation of viral infection GO:0019059 57 26 0,000 0,0708776 0,09119331 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,0708776 0,09114457 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,0708776 0,09109588 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,0708776 0,09104725 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,0708776 0,09099866 ! tube lumen formation GO:0035148 50 26 0,000 0,0708776 0,09095013 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,0708776 0,09090165 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,0708776 0,09085322 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,0708776 0,09080484 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,0708776 0,09075652 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,0708776 0,09070824 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,0708776 0,09066002 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,0708776 0,09061185 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,0708776 0,09056373 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,0708776 0,09051566 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,0708776 0,09046764 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,0708776 0,09041967 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,0708776 0,09037175 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,0708776 0,09032389 ! blastocyst development GO:0001824 49 26 0,000 0,0708776 0,09027607 ! leukocyte proliferation GO:0070661 52 26 0,000 0,0708776 0,0902283 GO:0032943|mononuclear cell proliferation, ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,0708776 0,09018059 ! neuron fate commitment GO:0048663 48 27 0,000 0,07350215 0,09347049 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,07350215 0,09342111 ! iron ion transport GO:0006826 59 27 0,000 0,07350215 0,09337179 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,07350215 0,09332252 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,07350215 0,0932733 ! fat cell differentiation GO:0045444 50 27 0,000 0,07350215 0,09322413 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,07350215 0,09317501 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,07350215 0,09312594 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,07350215 0,09307693 ! autophagy GO:0006914 41 27 0,000 0,07350215 0,09302797 ! male gonad development GO:0008584 44 27 0,000 0,07350215 0,09297906 ! response to toxin GO:0009636 47 27 0,000 0,07350215 0,0929302 ! primary neural tube formation GO:0014020 51 27 0,000 0,07350215 0,09288139 ! base-excision repair GO:0006284 41 27 0,000 0,07350215 0,09283263 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,07350215 0,09278393 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,07350215 0,09273527 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,07350215 0,09268667 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,07350215 0,09263812 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,07350215 0,09258962 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,07350215 0,09254117 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,07350215 0,09249277 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,07611937 0,09573613 ! circadian rhythm GO:0007623 50 28 0,000 0,07611937 0,09568611 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,07611937 0,09563614 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,07611937 0,09558623 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,07611937 0,09553637 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,07611937 0,09548656 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,07611937 0,0954368 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,07611937 0,09538709 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,07611937 0,09533744 ! synaptogenesis GO:0007416 42 28 0,000 0,07611937 0,09528783 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,07611937 0,09523828 ! lipid oxidation GO:0034440 43 28 0,000 0,07611937 0,09518878 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,07611937 0,09513933 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,07611937 0,09508993 ! translational initiation GO:0006413 65 29 0,000 0,07872929 0,09829926 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,07872929 0,09824828 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,07872929 0,09819734 ! regulation of pH GO:0006885 43 29 0,000 0,07872929 0,09814647 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,07872929 0,09809564 ! catechol metabolic process GO:0009712 54 29 0,000 0,07872929 0,09804486 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,07872929 0,09799414 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,07872929 0,09794347 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,07872929 0,09789286 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,07872929 0,09784229 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,07872929 0,09779178 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,07872929 0,09774132 ! cell fate determination GO:0001709 60 29 0,000 0,07872929 0,09769091 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,07872929 0,09764056 ! detection of light stimulus GO:0009583 38 29 0,000 0,07872929 0,09759025 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,07872929 0,09754 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,07872929 0,0974898 ! tissue homeostasis GO:0001894 48 29 0,000 0,07872929 0,09743965 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,07872929 0,09738955 ! phenol metabolic process GO:0018958 55 30 0,000 0,08133193 0,10055735 ! zinc ion transport GO:0006829 45 30 0,000 0,08133193 0,10050571 ! membrane docking GO:0022406 61 30 0,000 0,08133193 0,10045411 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,08133193 0,10040257 ! cell junction assembly GO:0034329 78 30 0,000 0,08133193 0,10035108 ! regulation of innate immune response GO:0045088 51 30 0,000 0,08133193 0,10029965 ! acute-phase response GO:0006953 49 30 0,000 0,08133193 0,10024826 ! myofibril assembly GO:0030239 47 30 0,000 0,08133193 0,10019693 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,08133193 0,10014566 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,08133193 0,10009443 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,08133193 0,10004326 ! phospholipid transport GO:0015914 51 30 0,000 0,08133193 0,09999214 ! ensheathment of neurons GO:0007272 57 30 0,000 0,08133193 0,09994107 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 51 30 0,000 0,08133193 0,09989005 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,08133193 0,09983909 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,08133193 0,09978818 ! eye morphogenesis GO:0048592 60 30 0,000 0,08133193 0,09973732 ! response to heat GO:0009408 50 30 0,000 0,08133193 0,09968651 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,08392729 0,10281521 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,08392729 0,10276288 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,08392729 0,10271061 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,08392729 0,1026584 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,08392729 0,10260623 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,08392729 0,10255412 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,08392729 0,10250206 ! ovulation cycle process GO:0022602 49 31 0,000 0,08392729 0,10245006 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,08392729 0,10239811 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,08392729 0,10234621 ! peptide transport GO:0015833 55 31 0,000 0,08392729 0,10229436 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,08392729 0,10224256 ! natural killer cell activation GO:0030101 45 31 0,000 0,08392729 0,10219082 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,08392729 0,10213913 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,08392729 0,10208749 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,08392729 0,10203591 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,08392729 0,10198438 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,08392729 0,10193289 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,08651541 0,10502325 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,08651541 0,10497029 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,08651541 0,10491738 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,08651541 0,10486452 ! cholesterol transport GO:0030301 56 32 0,000 0,08651541 0,10481172 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,08651541 0,10475897 ! spliceosome assembly GO:0000245 67 32 0,000 0,08651541 0,10470628 ! spindle organization GO:0007051 46 32 0,000 0,08651541 0,10465364 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,08651541 0,10460105 ! metanephros development GO:0001656 74 32 0,000 0,08651541 0,10454851 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,08651541 0,10449602 ! response to ionizing radiation GO:0010212 65 32 0,000 0,08651541 0,10444359 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,08651541 0,10439121 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,08651541 0,10433889 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,08651541 0,10428661 ! muscle cell development GO:0055001 49 32 0,000 0,08651541 0,10423439 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,08651541 0,10418222 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,08651541 0,10413011 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,08651541 0,10407804 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,08651541 0,10402603 ! ovulation cycle GO:0042698 51 32 0,000 0,08651541 0,10397407 ! peripheral nervous system development GO:0007422 64 32 0,000 0,08651541 0,10392216 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,08651541 0,1038703 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,08651541 0,10381849 ! gene silencing GO:0016458 65 32 0,000 0,08651541 0,10376674 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,08909631 0,10680902 ! post-embryonic development GO:0009791 69 33 0,000 0,08909631 0,10675583 ! protein targeting to membrane GO:0006612 68 33 0,000 0,08909631 0,10670269 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,08909631 0,10664961 ! ceramide metabolic process GO:0006672 64 33 0,000 0,08909631 0,10659657 ! sterol transport GO:0015918 57 33 0,000 0,08909631 0,10654359 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,08909631 0,10649067 GO:0060326|cell chemotaxis, ! adult locomotory behavior GO:0008344 59 33 0,000 0,08909631 0,10643779 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,08909631 0,10638497 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,08909631 0,1063322 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,09166999 0,10934953 ! glial cell differentiation GO:0010001 63 34 0,000 0,09166999 0,10929534 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,09166999 0,10924121 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,09166999 0,10918713 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,09166999 0,1091331 ! mismatch repair GO:0006298 46 34 0,000 0,09166999 0,10907913 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,09166999 0,10902521 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,09166999 0,10897135 ! regulation of muscle development GO:0048634 70 35 0,000 0,09423649 0,11196692 ! negative regulation of secretion GO:0051048 63 35 0,000 0,09423649 0,11191165 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,09423649 0,11185644 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,09423649 0,11180128 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,09423649 0,11174618 ! odontogenesis GO:0042476 66 35 0,000 0,09423649 0,11169114 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,09423649 0,11163614 ! female gonad development GO:0008585 58 35 0,000 0,09423649 0,1115812 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,09423649 0,11152632 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,09423649 0,11147149 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,09423649 0,11141671 ! cytokine production GO:0001816 59 35 0,000 0,09423649 0,11136199 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,09423649 0,11130732 ! neural tube formation GO:0001841 67 35 0,000 0,09423649 0,1112527 ! vesicle localization GO:0051648 64 35 0,000 0,09423649 0,11119814 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,09679583 0,11416214 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,09679583 0,1141062 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,09679583 0,11405032 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,09679583 0,1139945 ! cell junction organization GO:0034330 86 36 0,000 0,09679583 0,11393873 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,09679583 0,11388301 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,09679583 0,11382735 ! positive regulation of cell development GO:0010720 80 36 0,000 0,09679583 0,11377175 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,09679583 0,11371619 ! regulation of proteolysis GO:0030162 72 36 0,000 0,09679583 0,11366069 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,09679583 0,11360525 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,09679583 0,11354986 ! aerobic respiration GO:0009060 55 36 0,000 0,09679583 0,11349452 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,09679583 0,11343924 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,09679583 0,11338401 ! RNA export from nucleus GO:0006405 56 37 0,000 0,09934802 0,11631695 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,09934802 0,11626037 ! meiosis I GO:0007127 65 37 0,000 0,09934802 0,11620385 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,09934802 0,11614739 ! sister chromatid segregation GO:0000819 58 37 0,000 0,09934802 0,11609098 ! actomyosin structure organization GO:0031032 62 37 0,000 0,09934802 0,11603462 ! organic anion transport GO:0015711 68 37 0,000 0,09934802 0,11597832 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,09934802 0,11592208 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,09934802 0,11586589 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,09934802 0,11580975 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,09934802 0,11575367 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,09934802 0,11569764 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,09934802 0,11564167 ! pigment metabolic process GO:0042440 80 37 0,000 0,09934802 0,11558575 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,09934802 0,11552988 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,10189308 0,11843224 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,10189308 0,11837506 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,10189308 0,11831793 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,10189308 0,11826085 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,10189308 0,11820383 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,10189308 0,11814686 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,10189308 0,11808995 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,10189308 0,1180331 ! lipid homeostasis GO:0055088 67 38 0,000 0,10189308 0,1179763 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,10189308 0,11791955 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,10189308 0,11786286 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,10189308 0,11780622 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,10189308 0,11774964 ! mRNA catabolic process GO:0006402 71 39 0,000 0,10443103 0,12062461 ! mammary gland development GO:0030879 86 39 0,000 0,10443103 0,12056673 ! learning GO:0007612 77 39 0,000 0,10443103 0,1205089 ! ear morphogenesis GO:0042471 60 39 0,000 0,10443103 0,12045113 ! organic ether metabolic process GO:0018904 55 39 0,000 0,10443103 0,12039341 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,10443103 0,12033576 ! ion transmembrane transport GO:0034220 66 39 0,000 0,10443103 0,12027815 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,10443103 0,1202206 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,10443103 0,12016311 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,10443103 0,12010567 ! RNA modification GO:0009451 57 39 0,000 0,10443103 0,12004828 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,10696189 0,12289891 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,10696189 0,12284025 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,10696189 0,12278164 ! feeding behavior GO:0007631 59 40 0,000 0,10696189 0,12272309 ! negative regulation of binding GO:0051100 72 40 0,000 0,10696189 0,12266459 ! maintenance of protein location GO:0045185 91 40 0,000 0,10696189 0,12260615 ! cytokinesis GO:0000910 72 40 0,000 0,10696189 0,12254777 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,10948569 0,12537962 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,10948569 0,12531997 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,10948569 0,12526038 ! gliogenesis GO:0042063 88 41 0,000 0,10948569 0,12520084 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,10948569 0,12514137 ! T cell differentiation GO:0030217 81 41 0,000 0,10948569 0,12508194 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,10948569 0,12502258 ! female gamete generation GO:0007292 61 41 0,000 0,10948569 0,12496327 ! polyol metabolic process GO:0019751 66 41 0,000 0,10948569 0,12490402 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,10948569 0,12484482 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,11200244 0,12765413 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,11200244 0,12759369 ! regulation of tube size GO:0035150 71 42 0,000 0,11200244 0,1275333 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,11200244 0,12747298 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,11200244 0,1274127 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,11200244 0,12735249 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,11200244 0,12729233 ! neuron migration GO:0001764 79 42 0,000 0,11200244 0,12723223 ! regulation of protein secretion GO:0050708 71 42 0,000 0,11200244 0,12717219 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,11451216 0,1299605 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,11451216 0,12989922 ! glucose transport GO:0015758 65 43 0,000 0,11451216 0,12983801 ! neural tube development GO:0021915 77 43 0,000 0,11451216 0,12977685 ! striated muscle contraction GO:0006941 77 43 0,000 0,11451216 0,12971575 ! phagocytosis GO:0006909 90 43 0,000 0,11451216 0,12965471 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,11451216 0,12959372 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,11701487 0,13236379 ! hexose transport GO:0008645 67 44 0,000 0,11701487 0,13230158 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 0,000 0,11701487 0,13223944 ! double-strand break repair GO:0006302 81 44 0,000 0,11701487 0,13217736 ! biopolymer methylation GO:0043414 84 44 0,000 0,11701487 0,13211533 ! B cell differentiation GO:0030183 107 44 0,000 0,11701487 0,13205336 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,11701487 0,13199145 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,11701487 0,1319296 ! developmental growth GO:0048589 82 44 0,000 0,11701487 0,13186781 ! maintenance of location in cell GO:0051651 97 44 0,000 0,11701487 0,13180607 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,11951059 0,13455427 ! glycolysis GO:0006096 65 45 0,000 0,11951059 0,13449133 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,11951059 0,13442846 ! leukocyte migration GO:0050900 68 45 0,000 0,11951059 0,13436564 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,11951059 0,13430288 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,11951059 0,13424018 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,11951059 0,13417754 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,11951059 0,13411496 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,11951059 0,13405243 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,11951059 0,13398997 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,12199933 0,13671653 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,12199933 0,13665288 ! pigmentation GO:0043473 100 46 0,000 0,12199933 0,13658929 ! response to insulin stimulus GO:0032868 95 46 0,000 0,12199933 0,13652576 ! positive regulation of defense response GO:0031349 76 47 0,000 0,12448113 0,1392383 ! response to calcium ion GO:0051592 81 47 0,000 0,12448113 0,1391736 ! endosome transport GO:0016197 108 47 0,000 0,12448113 0,13910896 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,12448113 0,13904438 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,12448113 0,13897986 ! JNK cascade GO:0007254 91 47 0,000 0,12448113 0,1389154 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,12448113 0,13885099 ! methylation GO:0032259 90 47 0,000 0,12448113 0,13878665 ! protein homooligomerization GO:0051260 76 47 0,000 0,12448113 0,13872237 ! mitochondrial transport GO:0006839 82 48 0,000 0,12695599 0,14141487 ! Notch signaling pathway GO:0007219 96 48 0,000 0,12695599 0,14134943 ! cellular component disassembly GO:0022411 86 48 0,000 0,12695599 0,14128405 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,12695599 0,14121873 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,12695599 0,14115347 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,12695599 0,14108827 ! activation of caspase activity GO:0006919 84 48 0,000 0,12695599 0,14102314 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,12695599 0,14095806 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,12695599 0,14089304 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,12695599 0,14082808 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,12942394 0,14349954 ! regulation of action potential GO:0001508 95 49 0,000 0,12942394 0,14343344 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,12942394 0,1433674 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,12942394 0,14330142 ! regulation of ion transport GO:0043269 77 49 0,000 0,12942394 0,14323551 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,12942394 0,14316965 ! response to temperature stimulus GO:0009266 76 49 0,000 0,12942394 0,14310386 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,12942394 0,14303812 ! endocrine system development GO:0035270 104 49 0,000 0,12942394 0,14297245 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,12942394 0,14290684 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,12942394 0,14284128 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,12942394 0,14277579 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,12942394 0,14271036 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,13188499 0,14535744 ! neuromuscular process GO:0050905 99 50 0,000 0,13188499 0,14529088 ! inner ear development GO:0048839 79 50 0,000 0,13188499 0,14522439 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,13188499 0,14515796 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,13188499 0,14509158 ! viral infectious cycle GO:0019058 99 51 0,000 0,13433917 0,14772397 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,13433917 0,14765648 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,13433917 0,14758906 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,13433917 0,1475217 ! excretion GO:0007588 83 51 0,000 0,13433917 0,1474544 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,13433917 0,14738716 ! chromatin remodeling GO:0006338 109 51 0,000 0,13433917 0,14731998 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,13433917 0,14725287 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,13433917 0,14718581 ! vesicle organization GO:0016050 107 51 0,000 0,13433917 0,14711882 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,13433917 0,14705189 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,13678649 0,14966271 ! membrane fusion GO:0006944 110 52 0,000 0,13678649 0,14959468 ! positive regulation of growth GO:0045927 90 52 0,000 0,13678649 0,14952671 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,13678649 0,14945881 ! synapse organization GO:0050808 85 52 0,000 0,13678649 0,14939097 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,13922698 0,15198734 ! RNA catabolic process GO:0006401 93 53 0,000 0,13922698 0,15191841 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,13922698 0,15184955 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,13922698 0,15178074 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,13922698 0,151712 ! cell maturation GO:0048469 100 53 0,000 0,13922698 0,15164332 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,13922698 0,15157471 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,13922698 0,15150615 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,14166064 0,15408477 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,14166064 0,15401514 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,14166064 0,15394557 ! chloride transport GO:0006821 90 55 0,000 0,14408751 0,15651221 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,14408751 0,15644158 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,14408751 0,15637101 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,14408751 0,15630051 ! aging GO:0007568 103 55 0,000 0,14408751 0,15623008 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,14408751 0,1561597 ! RNA elongation GO:0006354 79 55 0,000 0,14408751 0,15608939 ! nuclear export GO:0051168 97 55 0,000 0,14408751 0,15601914 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,14408751 0,15594896 ! regulation of actin filament length GO:0030832 105 56 0,000 0,14650759 0,15849697 ! sensory perception of smell GO:0007608 80 56 0,000 0,14650759 0,15842574 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,14650759 0,15835456 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,14650759 0,15828346 ! regulation of DNA replication GO:0006275 101 56 0,000 0,14650759 0,15821242 ! proton transport GO:0015992 94 56 0,000 0,14650759 0,15814144 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,14650759 0,15807052 ! lipid modification GO:0030258 97 57 0,000 0,14892091 0,16060229 ! maintenance of location GO:0051235 118 57 0,000 0,14892091 0,16053034 ! hydrogen transport GO:0006818 97 58 0,000 0,15132749 0,16305147 ! regulation of endocytosis GO:0030100 91 58 0,000 0,15132749 0,16297849 ! adult behavior GO:0030534 99 58 0,000 0,15132749 0,16290557 ! positive regulation of secretion GO:0051047 95 59 0,000 0,15372734 0,16541502 ! regulation of cellular component size GO:0032535 109 59 0,000 0,15372734 0,16534107 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,15372734 0,1652672 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,15372734 0,16519338 ! DNA catabolic process GO:0006308 86 59 0,000 0,15372734 0,16511964 ! establishment of organelle localization GO:0051656 109 59 0,000 0,15372734 0,16504595 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,15612049 0,16754054 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,15612049 0,16746585 ! regulation of heart contraction GO:0008016 110 60 0,000 0,15612049 0,16739122 ! camera-type eye development GO:0043010 116 60 0,000 0,15612049 0,16731666 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,15612049 0,16724216 ! kidney development GO:0001822 122 60 0,000 0,15612049 0,16716773 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,15850694 0,16964756 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,15850694 0,16957212 ! tRNA processing GO:0008033 89 61 0,000 0,15850694 0,16949676 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,15850694 0,16942146 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,15850694 0,16934623 ! ear development GO:0043583 103 62 0,000 0,16088673 0,17181246 ! viral reproductive process GO:0022415 126 62 0,000 0,16088673 0,17173624 ! gonad development GO:0008406 98 62 0,000 0,16088673 0,17166008 ! regulation of mitosis GO:0007088 105 63 0,000 0,16325987 0,17411491 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,16325987 0,17403777 ! detection of external stimulus GO:0009581 91 63 0,000 0,16325987 0,17396069 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,16562637 0,17640419 ! cell redox homeostasis GO:0045454 102 64 0,000 0,16562637 0,17632613 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,16562637 0,17624814 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,16562637 0,17617023 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,16562637 0,17609238 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,16798626 0,1785225 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,16798626 0,17844369 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,16798626 0,17836494 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,17033956 0,18078384 ! actin filament organization GO:0007015 148 66 0,000 0,17033956 0,18070413 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,17033956 0,18062449 ! extracellular matrix organization GO:0030198 133 66 0,000 0,17033956 0,18054492 ! developmental maturation GO:0021700 116 66 0,000 0,17033956 0,18046542 ! cell projection assembly GO:0030031 120 66 0,000 0,17033956 0,18038599 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,17268627 0,18279066 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,17268627 0,18271028 ! activation of MAPK activity GO:0000187 115 67 0,000 0,17268627 0,18262996 ! chromosome segregation GO:0007059 113 67 0,000 0,17268627 0,18254972 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,17268627 0,18246955 ! hexose catabolic process GO:0019320 104 67 0,000 0,17268627 0,18238945 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,17268627 0,18230942 ! activation of immune response GO:0002253 105 67 0,000 0,17268627 0,18222946 ! amino acid transport GO:0006865 125 68 0,000 0,17502643 0,18461797 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,17502643 0,18453707 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,17502643 0,18445623 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 0,000 0,17502643 0,18437547 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,17502643 0,18429478 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,17502643 0,18421417 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,17736004 0,18658866 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,17736004 0,18650711 ! urogenital system development GO:0001655 137 69 0,000 0,17736004 0,18642563 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,17736004 0,18634422 ! antigen processing and presentation GO:0019882 104 69 0,000 0,17736004 0,18626288 ! appendage morphogenesis GO:0035107 135 70 0,000 0,17968713 0,18862445 GO:0035108|limb morphogenesis, ! reproductive structure development GO:0048608 113 71 0,000 0,18200771 0,19097713 ! appendage development GO:0048736 136 71 0,000 0,18200771 0,19089388 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,18200771 0,1908107 ! B cell activation GO:0042113 160 71 0,000 0,18200771 0,1907276 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,18200771 0,19064456 ! regulation of immune effector process GO:0002697 137 71 0,000 0,18200771 0,1905616 ! acute inflammatory response GO:0002526 113 72 0,000 0,18432181 0,19290051 ! regulation of caspase activity GO:0043281 122 72 0,000 0,18432181 0,19281664 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,18432181 0,19273285 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,18432181 0,19264912 ! carbohydrate transport GO:0008643 110 72 0,000 0,18432181 0,19256547 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,18432181 0,19248189 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,18432181 0,19239838 ! learning or memory GO:0007611 147 73 0,000 0,18662944 0,19472265 ! regulation of blood pressure GO:0008217 125 73 0,000 0,18662944 0,19463824 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,18662944 0,19455391 ! axon guidance GO:0007411 139 73 0,000 0,18662944 0,19446965 ! fertilization GO:0009566 90 73 0,000 0,18662944 0,19438547 ! transition metal ion transport GO:0000041 126 74 0,000 0,18893061 0,19669712 ! neurotransmitter transport GO:0006836 123 74 0,000 0,18893061 0,19661205 ! meiosis GO:0007126 121 74 0,000 0,18893061 0,19652704 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,18893061 0,19644211 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,18893061 0,19635726 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,18893061 0,19627248 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,18893061 0,19618777 ! eye development GO:0001654 143 74 0,000 0,18893061 0,19610313 ! organelle localization GO:0051640 136 74 0,000 0,18893061 0,19601857 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,19122535 0,19831388 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,19122535 0,19822844 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,19122535 0,19814307 ! meiotic cell cycle GO:0051321 122 75 0,000 0,19122535 0,19805777 ! rhythmic process GO:0048511 128 75 0,000 0,19122535 0,19797255 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,19122535 0,1978874 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,19351368 0,20016935 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,19351368 0,20008333 ! defense response to bacterium GO:0042742 89 76 0,000 0,19351368 0,19999738 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,19351368 0,19991151 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,19351368 0,19982571 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,1957956 0,20209533 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,1957956 0,20200867 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,1957956 0,20192208 ! blood coagulation GO:0007596 146 78 0,000 0,19807115 0,20418131 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,19807115 0,20409387 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,19807115 0,2040065 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,19807115 0,20391921 ! protein oligomerization GO:0051259 139 78 0,000 0,19807115 0,20383199 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,20034033 0,20607902 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,20034033 0,20599096 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,20034033 0,20590296 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,20034033 0,20581504 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,20034033 0,2057272 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,20260317 0,20796212 ! response to metal ion GO:0010038 140 80 0,000 0,20260317 0,20787344 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,20260317 0,20778483 ! inorganic anion transport GO:0015698 138 80 0,000 0,20260317 0,2076963 ! T cell activation GO:0042110 168 81 0,000 0,20485967 0,20992009 ! digestion GO:0007586 112 81 0,000 0,20485967 0,20983073 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,20485967 0,20974144 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,20485967 0,20965222 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,20710987 0,21186495 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,20710987 0,21177491 ! response to drug GO:0042493 143 82 0,000 0,20710987 0,21168494 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,20710987 0,21159505 ! regulation of lyase activity GO:0051339 160 83 0,000 0,20935378 0,21379677 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,2115914 0,21599021 ! hemostasis GO:0007599 158 84 0,000 0,2115914 0,21589861 ! negative regulation of transport GO:0051051 153 84 0,000 0,2115914 0,21580709 ! regulation of ligase activity GO:0051340 142 84 0,000 0,2115914 0,21571564 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,2115914 0,21562428 ! response to unfolded protein GO:0006986 131 85 0,000 0,21382277 0,21780593 ! nucleosome assembly GO:0006334 122 85 0,000 0,21382277 0,21771375 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,21382277 0,21762166 ! amine biosynthetic process GO:0009309 138 86 0,000 0,2160479 0,21979334 ! response to inorganic substance GO:0010035 153 86 0,000 0,2160479 0,21970045 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,2160479 0,21960763 ! chromatin assembly GO:0031497 124 86 0,000 0,2160479 0,21951489 ! tube morphogenesis GO:0035239 176 86 0,000 0,2160479 0,21942223 ! mitochondrion organization GO:0007005 148 86 0,000 0,2160479 0,21932964 ! alcohol catabolic process GO:0046164 130 86 0,000 0,2160479 0,21923714 ! amine transport GO:0015837 155 86 0,000 0,2160479 0,21914471 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,21826681 0,22130212 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cellular respiration GO:0045333 135 88 0,000 0,22047951 0,22345143 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,22047951 0,22335734 ! gland development GO:0048732 206 88 0,000 0,22047951 0,22326334 ! regulation of neurological system process GO:0031644 148 88 0,000 0,22047951 0,22316941 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,22047951 0,22307556 ! cellular defense response GO:0006968 114 89 0,000 0,22268601 0,22521335 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,22268601 0,22511872 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,22488635 0,22724761 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,22488635 0,22715221 ! sex differentiation GO:0007548 145 90 0,000 0,22488635 0,22705689 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,22488635 0,22696164 ! sterol metabolic process GO:0016125 152 91 0,000 0,22708053 0,22907998 ! response to protein stimulus GO:0051789 149 91 0,000 0,22708053 0,22898397 ! regulation of defense response GO:0031347 149 92 0,000 0,22926857 0,2310935 ! nucleosome organization GO:0034728 138 92 0,000 0,22926857 0,23099673 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,22926857 0,23090004 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,23145049 0,23299995 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,23145049 0,2329025 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,23145049 0,23280514 ! regulation of membrane potential GO:0042391 164 93 0,000 0,23145049 0,23270785 ! female pregnancy GO:0007565 164 94 0,000 0,23362631 0,23479737 ! transcription initiation GO:0006352 153 94 0,000 0,23362631 0,23469933 ! regulation of T cell activation GO:0050863 158 94 0,000 0,23362631 0,23460138 ! forebrain development GO:0030900 188 95 0,000 0,23579604 0,23668138 ! leukocyte differentiation GO:0002521 202 96 0,000 0,2379597 0,23875356 ! mRNA transport GO:0051028 169 96 0,000 0,2379597 0,23865403 ! positive regulation of immune response GO:0050778 156 96 0,000 0,2379597 0,2385546 ! detection of stimulus GO:0051606 151 96 0,000 0,2379597 0,23845524 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,2401173 0,24051716 ! hormone metabolic process GO:0042445 157 97 0,000 0,2401173 0,24041707 ! response to virus GO:0009615 160 98 0,000 0,24226887 0,24247042 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,24441441 0,24451604 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,24441441 0,24441441