pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/966-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! glutathione biosynthetic process GO:0006750 15 12 4,000 7,683E-11 1,877E-07 ! peptide biosynthetic process GO:0043043 26 19 4,000 1,112E-09 1,359E-06 ! UTP metabolic process GO:0046051 10 9 3,000 5,015E-09 4,084E-06 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! CTP metabolic process GO:0046036 11 10 3,000 8,342E-09 5,095E-06 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 10 3,000 8,342E-09 4,076E-06 ! glutathione metabolic process GO:0006749 42 28 4,000 9,232E-09 3,759E-06 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 4,000 1,113E-08 3,885E-06 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 3,000 1,308E-08 3,995E-06 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 3,000 2,824E-08 7,665E-06 ! coenzyme biosynthetic process GO:0009108 119 72 5,000 3,249E-08 7,938E-06 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 3,000 5,37E-08 1,193E-05 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 3,000 7,145E-08 1,455E-05 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 3,000 1,197E-07 2,249E-05 ! regulation of keratinocyte differentiation GO:0045616 6 5 2,000 1,617E-07 2,822E-05 ! cofactor biosynthetic process GO:0051188 161 95 5,000 1,724E-07 2,808E-05 ! peptide metabolic process GO:0006518 80 51 4,000 2,107E-07 3,216E-05 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 3,000 2,838E-07 4,079E-05 ! sulfur compound biosynthetic process GO:0044272 108 58 4,000 4,051E-07 5,499E-05 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 4,000 4,051E-07 5,209E-05 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 3,000 4,107E-07 5,017E-05 ! pyrimidine nucleoside metabolic process GO:0006213 34 24 3,000 4,107E-07 4,778E-05 ! regulation of epidermal cell differentiation GO:0045604 8 7 2,000 5,64E-07 6,263E-05 ! water-soluble vitamin biosynthetic process GO:0042364 44 26 3,000 5,756E-07 6,113E-05 ! vitamin biosynthetic process GO:0009110 48 28 3,000 7,852E-07 7,992E-05 ! positive regulation of epidermis development GO:0045684 13 8 2,000 9,007E-07 8,801E-05 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 9,007E-07 8,463E-05 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 1,923E-06 1,74E-04 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 3,000 2,224E-06 1,94E-04 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 2,000 2,639E-06 2,223E-04 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 2,000 2,639E-06 2,149E-04 ! ribonucleoside metabolic process GO:0009119 64 42 3,000 4,176E-06 3,291E-04 ! cartilage condensation GO:0001502 22 13 2,000 4,557E-06 3,479E-04 ! regulation of monooxygenase activity GO:0032768 35 13 2,000 4,557E-06 3,374E-04 ! regulation of epidermis development GO:0045682 19 13 2,000 4,557E-06 3,275E-04 ! regulation of epithelial cell proliferation GO:0050678 122 45 3,000 5,527E-06 3,858E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 3,000 6,041E-06 4,1E-04 ! cartilage development GO:0051216 99 53 3,000 1,069E-05 7,061E-04 ! positive regulation of cell migration GO:0030335 137 58 3,000 1,534E-05 9,864E-04 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 2,000 1,793E-05 1,123E-03 ! nucleoside metabolic process GO:0009116 91 62 3,000 2,002E-05 1,222E-03 ! water-soluble vitamin metabolic process GO:0006767 107 63 3,000 2,133E-05 1,271E-03 ! positive regulation of cell motion GO:0051272 157 65 3,000 2,415E-05 1,405E-03 ! lung development GO:0030324 165 69 3,000 3,06E-05 1,738E-03 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 3,16E-05 1,755E-03 ! respiratory tube development GO:0030323 171 72 3,000 3,62E-05 1,965E-03 ! respiratory system development GO:0060541 175 74 3,000 4,033E-05 2,142E-03 ! regulation of endothelial cell proliferation GO:0001936 60 27 2,000 4,541E-05 2,361E-03 ! response to hypoxia GO:0001666 178 81 3,000 5,752E-05 2,928E-03 ! response to oxygen levels GO:0070482 183 83 3,000 6,329E-05 3,155E-03 ! hemoglobin biosynthetic process GO:0042541 8 5 1,000 6,45E-05 3,152E-03 ! benzene and derivative metabolic process GO:0042537 12 5 1,000 6,45E-05 3,09E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 6,45E-05 3,03E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 6,45E-05 2,973E-03 ! mRNA transcription GO:0009299 10 5 1,000 6,45E-05 2,918E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 6,45E-05 2,865E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 6,45E-05 2,814E-03 ! indolalkylamine catabolic process GO:0046218 8 5 1,000 6,45E-05 2,765E-03 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 6,45E-05 2,717E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 6,45E-05 2,671E-03 ! negative regulation of growth GO:0045926 168 85 3,000 6,946E-05 2,828E-03 ! ossification GO:0001503 205 91 3,000 9,062E-05 3,629E-03 ! bone development GO:0060348 206 92 3,000 9,456E-05 3,726E-03 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 9,659E-05 3,746E-03 ! embryonic hemopoiesis GO:0035162 16 6 1,000 9,659E-05 3,687E-03 ! response to interferon-gamma GO:0034341 16 6 1,000 9,659E-05 3,63E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 9,659E-05 3,575E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 9,659E-05 3,522E-03 ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 9,659E-05 3,47E-03 ! oxygen homeostasis GO:0032364 10 6 1,000 9,659E-05 3,42E-03 ! vitamin metabolic process GO:0006766 153 93 3,000 9,861E-05 3,442E-03 ! tissue remodeling GO:0048771 78 37 2,000 1,184E-04 4,075E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 1,208E-04 4,1E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,35E-04 4,518E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 1,35E-04 4,457E-03 ! mRNA stabilization GO:0048255 18 7 1,000 1,35E-04 4,398E-03 GO:0043489|RNA stabilization, ! tryptophan metabolic process GO:0006568 11 7 1,000 1,35E-04 4,34E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 1,35E-04 4,283E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 1,797E-04 5,629E-03 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 1,797E-04 5,557E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,797E-04 5,488E-03 ! hemoglobin metabolic process GO:0020027 14 8 1,000 1,797E-04 5,42E-03 ! ER overload response GO:0006983 13 8 1,000 1,797E-04 5,354E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,797E-04 5,29E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,797E-04 5,227E-03 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 1,000 1,797E-04 5,165E-03 ! gas homeostasis GO:0033483 14 8 1,000 1,797E-04 5,105E-03 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 1,000 1,797E-04 5,046E-03 ! NAD biosynthetic process GO:0009435 17 8 1,000 1,797E-04 4,989E-03 ! regulation of myeloid cell differentiation GO:0045637 105 43 2,000 1,86E-04 5,106E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 2,307E-04 6,261E-03 ! induction of positive chemotaxis GO:0050930 17 9 1,000 2,307E-04 6,193E-03 ! regulation of glycolysis GO:0006110 20 9 1,000 2,307E-04 6,125E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 2,307E-04 6,059E-03 ! regulation of macrophage differentiation GO:0045649 16 9 1,000 2,307E-04 5,995E-03 ! positive regulation of DNA binding GO:0043388 83 48 2,000 2,583E-04 6,642E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 2,879E-04 7,325E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 2,879E-04 7,25E-03 ! lung alveolus development GO:0048286 26 10 1,000 2,879E-04 7,176E-03 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 1,000 2,879E-04 7,103E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 2,879E-04 7,032E-03 ! induction of an organ GO:0001759 17 10 1,000 2,879E-04 6,963E-03 ! midbrain development GO:0030901 14 10 1,000 2,879E-04 6,894E-03 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 1,000 2,879E-04 6,827E-03 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 2,879E-04 6,762E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 2,879E-04 6,697E-03 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of binding GO:0051099 88 52 2,000 3,276E-04 7,55E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 3,512E-04 8,019E-03 ! blood vessel remodeling GO:0001974 30 11 1,000 3,512E-04 7,945E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 3,512E-04 7,872E-03 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 1,000 3,512E-04 7,801E-03 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 3,512E-04 7,73E-03 ! response to UV GO:0009411 120 55 2,000 3,867E-04 8,436E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 4,208E-04 9,097E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 4,208E-04 9,017E-03 ! regulation of positive chemotaxis GO:0050926 22 12 1,000 4,208E-04 8,939E-03 GO:0050927|positive regulation of positive chemotaxis, ! histone acetylation GO:0016573 27 12 1,000 4,208E-04 8,862E-03 ! regulation of hormone metabolic process GO:0032350 28 12 1,000 4,208E-04 8,786E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 4,208E-04 8,712E-03 ! regulation of leukocyte migration GO:0002685 29 12 1,000 4,208E-04 8,638E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 4,208E-04 8,566E-03 ! developmental induction GO:0031128 22 12 1,000 4,208E-04 8,496E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 1,000 4,208E-04 8,426E-03 ! localization within membrane GO:0051668 26 12 1,000 4,208E-04 8,357E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 4,297E-04 8,467E-03 ! regulation of bone remodeling GO:0046850 143 57 2,000 4,297E-04 8,399E-03 ! regulation of tissue remodeling GO:0034103 146 58 2,000 4,524E-04 8,771E-03 ! regulation of chemokine production GO:0032642 18 13 1,000 4,965E-04 9,55E-03 ! indolalkylamine metabolic process GO:0006586 19 13 1,000 4,965E-04 9,475E-03 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 4,965E-04 9,402E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of erythrocyte differentiation GO:0045646 47 13 1,000 4,965E-04 9,33E-03 ! aromatic amino acid family catabolic process GO:0009074 20 13 1,000 4,965E-04 9,258E-03 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 1,000 4,965E-04 9,188E-03 ! regulation of mRNA stability GO:0043488 32 13 1,000 4,965E-04 9,119E-03 ! biogenic amine catabolic process GO:0042402 24 13 1,000 4,965E-04 9,051E-03 ! regulation of RNA splicing GO:0043484 22 13 1,000 4,965E-04 8,984E-03 ! regulation of homeostatic process GO:0032844 148 62 2,000 5,504E-04 9,886E-03 ! skeletal system morphogenesis GO:0048705 118 63 2,000 5,768E-04 0,0102858 ! hair follicle morphogenesis GO:0031069 27 14 1,000 5,782E-04 0,01023649 ! regulation of RNA stability GO:0043487 33 14 1,000 5,782E-04 0,01016284 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 6,661E-04 0,01162321 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 6,661E-04 0,01154077 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 6,661E-04 0,0114595 ! muscle maintenance GO:0046716 26 15 1,000 6,661E-04 0,01137936 ! epithelial to mesenchymal transition GO:0001837 30 15 1,000 6,661E-04 0,01130034 ! negative regulation of cell growth GO:0030308 142 67 2,000 6,907E-04 0,0116373 ! negative regulation of cell size GO:0045792 144 69 2,000 7,527E-04 0,01259402 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 7,527E-04 0,01250835 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 7,6E-04 0,0125447 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 1,000 7,6E-04 0,01246051 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 7,6E-04 0,01237744 ! negative regulation of kinase activity GO:0033673 145 70 2,000 7,849E-04 0,01269878 ! NAD metabolic process GO:0019674 33 17 1,000 8,599E-04 0,01382014 ! myoblast differentiation GO:0045445 50 17 1,000 8,599E-04 0,01372981 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 8,599E-04 0,01364066 ! cellular amino acid derivative catabolic process GO:0042219 30 17 1,000 8,599E-04 0,01355266 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 8,599E-04 0,01346578 ! negative regulation of transferase activity GO:0051348 155 74 2,000 9,227E-04 0,01435702 ! heart looping GO:0001947 34 18 1,000 9,657E-04 0,01493234 ! epidermis morphogenesis GO:0048730 43 18 1,000 9,657E-04 0,01483843 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 9,657E-04 0,01474569 ! neural crest cell migration GO:0001755 41 18 1,000 9,657E-04 0,0146541 ! regulation of BMP signaling pathway GO:0030510 33 18 1,000 9,657E-04 0,01456364 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 1,000 9,657E-04 0,0144743 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 9,657E-04 0,01438604 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 1,078E-03 0,01595447 ! peptide cross-linking GO:0018149 39 19 1,000 1,078E-03 0,01585836 ! positive regulation of angiogenesis GO:0045766 50 20 1,000 1,195E-03 0,01748574 ! protein amino acid acetylation GO:0006473 41 20 1,000 1,195E-03 0,01738166 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 1,195E-03 0,01727881 ! response to vitamin GO:0033273 36 20 1,000 1,195E-03 0,01717717 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 1,195E-03 0,01707672 GO:0010675|regulation of cellular carbohydrate metabolic process, ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 1,195E-03 0,01697743 ! aromatic compound catabolic process GO:0019439 31 20 1,000 1,195E-03 0,0168793 ! muscle cell differentiation GO:0042692 178 81 2,000 1,199E-03 0,01683148 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 1,319E-03 0,01841217 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 1,319E-03 0,01830756 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 1,448E-03 0,01999123 ! positive regulation of locomotion GO:0040017 44 22 1,000 1,448E-03 0,01987892 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 1,000 1,448E-03 0,01976786 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 1,448E-03 0,01965804 ! peptidyl-serine modification GO:0018209 50 22 1,000 1,448E-03 0,01954943 ! positive regulation of B cell activation GO:0050871 42 22 1,000 1,448E-03 0,01944202 ! response to cytokine stimulus GO:0034097 69 22 1,000 1,448E-03 0,01933578 ! regulation of DNA binding GO:0051101 167 89 2,000 1,572E-03 0,02087568 ! regulation of chemotaxis GO:0050920 45 23 1,000 1,584E-03 0,0209135 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 1,725E-03 0,02265433 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 1,725E-03 0,02253319 ! aromatic amino acid family metabolic process GO:0009072 37 24 1,000 1,725E-03 0,02241333 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 1,872E-03 0,02419313 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 1,872E-03 0,0240658 ! dicarboxylic acid metabolic process GO:0043648 48 25 1,000 1,872E-03 0,0239398 ! vasculogenesis GO:0001570 49 25 1,000 1,872E-03 0,02381511 ! regulation of behavior GO:0050795 48 25 1,000 1,872E-03 0,02369172 ! molting cycle process GO:0022404 52 26 1,000 2,024E-03 0,02549129 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 2,024E-03 0,02536056 GO:0045936|negative regulation of phosphate metabolic process, ! osteoblast differentiation GO:0001649 63 26 1,000 2,024E-03 0,02523117 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 2,024E-03 0,02510309 ! neural crest cell development GO:0014032 59 26 1,000 2,024E-03 0,02497631 GO:0014033|neural crest cell differentiation, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 2,024E-03 0,0248508 ! embryonic pattern specification GO:0009880 49 27 1,000 2,183E-03 0,02666029 ! cellular response to oxidative stress GO:0034599 43 27 1,000 2,183E-03 0,02652766 ! skeletal muscle tissue development GO:0007519 223 100 2,000 2,194E-03 0,02653269 GO:0060538|skeletal muscle organ development, ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 2,347E-03 0,02823978 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 2,347E-03 0,02810135 ! spliceosomal snRNP biogenesis GO:0000387 40 28 1,000 2,347E-03 0,02796427 ! protein amino acid acylation GO:0043543 59 28 1,000 2,347E-03 0,02782853 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 2,516E-03 0,02969609 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 2,516E-03 0,02955332 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 2,516E-03 0,02941192 ! somitogenesis GO:0001756 52 29 1,000 2,516E-03 0,02927186 ! nicotinamide metabolic process GO:0006769 56 30 1,000 2,691E-03 0,03116223 GO:0046496|nicotinamide nucleotide metabolic process, ! regulation of B cell activation GO:0050864 55 30 1,000 2,691E-03 0,03101523 ! alkaloid metabolic process GO:0009820 57 31 1,000 2,872E-03 0,03294377 ! iron ion homeostasis GO:0055072 60 31 1,000 2,872E-03 0,03278982 ! erythrocyte differentiation GO:0030218 62 31 1,000 2,872E-03 0,03263731 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 2,872E-03 0,03248622 ! collagen metabolic process GO:0032963 49 32 1,000 3,059E-03 0,03443501 ! mesoderm formation GO:0001707 73 32 1,000 3,059E-03 0,03427705 ! BMP signaling pathway GO:0030509 71 32 1,000 3,059E-03 0,03412054 ! hindbrain development GO:0030902 65 32 1,000 3,059E-03 0,03396544 ! positive regulation of catabolic process GO:0009896 72 32 1,000 3,059E-03 0,03381175 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 3,251E-03 0,03577155 ! pyridine nucleotide metabolic process GO:0019362 60 33 1,000 3,251E-03 0,03561114 ! formation of primary germ layer GO:0001704 76 34 1,000 3,448E-03 0,03760541 ! cell fate specification GO:0001708 56 34 1,000 3,448E-03 0,03743827 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 1,000 3,651E-03 0,03946597 ! mesoderm morphogenesis GO:0048332 80 35 1,000 3,651E-03 0,03929211 ! calcium-mediated signaling GO:0019722 67 35 1,000 3,651E-03 0,03911978 ! placenta development GO:0001890 53 35 1,000 3,651E-03 0,03894895 ! embryonic organ development GO:0048568 67 36 1,000 3,859E-03 0,04099264 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 4,073E-03 0,04307591 ! xenobiotic metabolic process GO:0006805 55 37 1,000 4,073E-03 0,04289024 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 4,073E-03 0,04270616 ! spermatid development GO:0007286 69 38 1,000 4,292E-03 0,04481165 ! glycogen metabolic process GO:0005977 63 38 1,000 4,292E-03 0,04462096 ! carbohydrate homeostasis GO:0033500 59 39 1,000 4,517E-03 0,04675596 GO:0042593|glucose homeostasis, ! erythrocyte homeostasis GO:0034101 75 39 1,000 4,517E-03 0,04655868 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 4,517E-03 0,04636305 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 1,000 4,517E-03 0,04616907 GO:0006073|cellular glucan metabolic process, ! cellular amide metabolic process GO:0043603 73 41 1,000 4,982E-03 0,05070987 ! multicellular organismal metabolic process GO:0044236 64 41 1,000 4,982E-03 0,05049945 ! mesenchymal cell development GO:0014031 94 41 1,000 4,982E-03 0,05029078 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! spermatid differentiation GO:0048515 73 41 1,000 4,982E-03 0,05008382 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 5,222E-03 0,0522857 ! response to xenobiotic stimulus GO:0009410 63 42 1,000 5,222E-03 0,05207229 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 5,468E-03 0,05430029 GO:0090047|positive regulation of transcription regulator activity, ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 5,468E-03 0,05408045 ! striated muscle cell differentiation GO:0051146 91 43 1,000 5,468E-03 0,05386239 ! hormone-mediated signaling GO:0009755 84 43 1,000 5,468E-03 0,05364607 ! segmentation GO:0035282 78 43 1,000 5,468E-03 0,05343149 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 1,000 5,719E-03 0,05566049 ! energy reserve metabolic process GO:0006112 76 44 1,000 5,719E-03 0,05543961 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 5,719E-03 0,05522048 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 5,719E-03 0,05500308 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 5,975E-03 0,05724068 ! keratinocyte differentiation GO:0030216 81 45 1,000 5,975E-03 0,05701708 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 1,000 5,975E-03 0,05679523 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 6,236E-03 0,05904875 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 6,236E-03 0,05882076 ! cell growth GO:0016049 90 46 1,000 6,236E-03 0,05859453 ! positive regulation of protein transport GO:0051222 80 46 1,000 6,236E-03 0,05837003 ! positive regulation of cell cycle GO:0045787 96 48 1,000 6,774E-03 0,06316244 ! vascular process in circulatory system GO:0003018 85 48 1,000 6,774E-03 0,06292228 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 7,05E-03 0,0652432 ! regulation of ossification GO:0030278 123 50 1,000 7,332E-03 0,06759319 ! epidermal cell differentiation GO:0009913 87 50 1,000 7,332E-03 0,06733908 ! positive regulation of cytokine production GO:0001819 94 50 1,000 7,332E-03 0,06708687 ! histone modification GO:0016570 104 52 1,000 7,91E-03 0,07210803 ! amino acid activation GO:0043038 98 52 1,000 7,91E-03 0,07183997 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 8,207E-03 0,07425773 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of angiogenesis GO:0045765 125 54 1,000 8,509E-03 0,07670223 ! regulation of translational initiation GO:0006446 87 54 1,000 8,509E-03 0,07642023 ! activation of phospholipase C activity GO:0007202 110 54 1,000 8,509E-03 0,0761403 GO:0010863|positive regulation of phospholipase C activity, ! covalent chromatin modification GO:0016569 115 54 1,000 8,509E-03 0,07586242 ! regulation of cell shape GO:0008360 142 54 1,000 8,509E-03 0,07558656 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 8,815E-03 0,0780255 ! cell recognition GO:0008037 98 55 1,000 8,815E-03 0,07774382 ! skeletal muscle fiber development GO:0048741 130 56 1,000 9,126E-03 0,08020045 ! muscle fiber development GO:0048747 131 57 1,000 9,443E-03 0,08268209 ! regulation of phospholipase activity GO:0010517 113 57 1,000 9,443E-03 0,0823868 ! heart morphogenesis GO:0003007 105 57 1,000 9,443E-03 0,0820936 ! regulation of intracellular transport GO:0032386 108 57 1,000 9,443E-03 0,08180249 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 9,764E-03 0,08428517 ! gastrulation GO:0007369 122 58 1,000 9,764E-03 0,08398839 ! positive regulation of lipase activity GO:0060193 115 58 1,000 9,764E-03 0,08369369 ! heterocycle catabolic process GO:0046700 100 60 1,000 0,01042027 0,0890095 ! mesoderm development GO:0007498 128 63 1,000 0,01144078 0,09738614 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,01179035 0,10001328 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 0,01179035 0,09966722 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,01250344 0,10533071 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 0,01250344 0,10496875 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01273637 0,10655805 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01273637 0,10619437 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01273637 0,10583316 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01273637 0,10547441 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01273637 0,10511808 ! neuron fate determination GO:0048664 7 5 0,000 0,01273637 0,10476414 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01273637 0,10441258 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01273637 0,10406338 ! polyol transport GO:0015791 12 5 0,000 0,01273637 0,1037165 ! response to superoxide GO:0000303 10 5 0,000 0,01273637 0,10337193 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01273637 0,10302964 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01273637 0,1026896 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01273637 0,10235181 ! female meiosis GO:0007143 10 5 0,000 0,01273637 0,10201623 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01273637 0,10168284 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01273637 0,10135163 ! hypothalamus development GO:0021854 9 5 0,000 0,01273637 0,10102257 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01273637 0,10069563 ! cobalt ion transport GO:0006824 11 5 0,000 0,01273637 0,10037081 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01273637 0,10004807 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01273637 0,0997274 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01273637 0,09940879 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01273637 0,0990922 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01273637 0,09877762 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01273637 0,09846503 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01273637 0,09815442 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01273637 0,09784576 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01273637 0,09753903 ! transposition GO:0032196 9 5 0,000 0,01273637 0,09723422 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01273637 0,09693131 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01273637 0,09663028 ! negative chemotaxis GO:0050919 16 5 0,000 0,01273637 0,09633112 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01273637 0,0960338 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01273637 0,09573831 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01273637 0,09544463 ! behavioral response to pain GO:0048266 10 5 0,000 0,01273637 0,09515275 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01273637 0,09486265 ! Notch receptor processing GO:0007220 11 5 0,000 0,01273637 0,09457432 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01273637 0,09428773 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01273637 0,09400287 ! micturition GO:0060073 9 5 0,000 0,01273637 0,09371973 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01273637 0,09343829 ! copulation GO:0007620 9 5 0,000 0,01273637 0,09315853 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01273637 0,09288045 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01273637 0,09260402 ! bioluminescence GO:0008218 9 5 0,000 0,01273637 0,09232923 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01273637 0,09205607 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01273637 0,09178451 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01273637 0,09151456 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01273637 0,09124619 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01273637 0,09097939 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01273637 0,09071414 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01273637 0,09045044 ! grooming behavior GO:0007625 6 5 0,000 0,01273637 0,09018826 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01273637 0,0899276 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01273637 0,08966844 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01273637 0,08941078 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01273637 0,08915459 ! response to protozoan GO:0001562 13 5 0,000 0,01273637 0,08889986 ! lymph vessel development GO:0001945 10 5 0,000 0,01273637 0,08864658 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01273637 0,08839475 ! endochondral ossification GO:0001958 17 5 0,000 0,01273637 0,08814434 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01273637 0,08789534 ! single strand break repair GO:0000012 8 5 0,000 0,01273637 0,08764775 ! parathyroid gland development GO:0060017 14 5 0,000 0,01273637 0,08740155 ! anagen GO:0042640 7 5 0,000 0,01273637 0,08715672 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01273637 0,08691327 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01273637 0,08667117 ! cytokine secretion GO:0050663 15 5 0,000 0,01273637 0,08643042 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01273637 0,086191 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01273637 0,0859529 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01273637 0,08571612 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01273637 0,08548063 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01273637 0,08524644 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01273637 0,08501353 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01273637 0,08478188 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01273637 0,0845515 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01273637 0,08432236 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01273637 0,08409446 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01273637 0,08386779 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01273637 0,08364234 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01273637 0,0834181 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01273637 0,08319505 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01273637 0,0829732 ! microvillus organization GO:0032528 8 5 0,000 0,01273637 0,08275253 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01273637 0,08253302 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01273637 0,08231468 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01273637 0,08209749 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01273637 0,08188145 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01273637 0,08166654 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01273637 0,08145275 ! polyol catabolic process GO:0046174 9 5 0,000 0,01273637 0,08124008 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01273637 0,08102852 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01273637 0,08081805 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01273637 0,08060868 ! muscle cell migration GO:0014812 8 5 0,000 0,01273637 0,08040039 ! mitochondrial fission GO:0000266 8 5 0,000 0,01273637 0,08019317 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01273637 0,07998702 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01273637 0,07978192 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01273637 0,07957788 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01273637 0,07937487 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01273637 0,0791729 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01273637 0,07897196 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01273637 0,07877203 ! monocyte activation GO:0042117 10 5 0,000 0,01273637 0,07857311 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01273637 0,07837519 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01273637 0,07817827 ! response to food GO:0032094 6 5 0,000 0,01273637 0,07798233 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01273637 0,07778738 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01273637 0,07759339 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01273637 0,07740037 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01273637 0,07720831 ! forebrain neuron development GO:0021884 13 5 0,000 0,01273637 0,0770172 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01273637 0,07682704 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01273637 0,07663781 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01273637 0,07644951 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01273637 0,07626213 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01273637 0,07607567 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01273637 0,07589012 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01273637 0,07570548 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01273637 0,07552172 ! lipid glycosylation GO:0030259 7 5 0,000 0,01273637 0,07533886 ! nucleobase transport GO:0015851 6 5 0,000 0,01273637 0,07515688 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01273637 0,07497578 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01273637 0,07479555 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01273637 0,07461619 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01273637 0,07443768 ! basic amino acid transport GO:0015802 12 5 0,000 0,01273637 0,07426002 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01273637 0,07408321 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01273637 0,07390725 ! actin nucleation GO:0045010 11 5 0,000 0,01273637 0,07373211 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01273637 0,0735578 ! depurination GO:0045007 5 5 0,000 0,01273637 0,07338432 ! depyrimidination GO:0045008 10 5 0,000 0,01273637 0,07321165 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01273637 0,07303979 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01273637 0,07286874 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01273637 0,07269848 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01273637 0,07252902 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01273637 0,07236035 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01273637 0,07219246 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01273637 0,07202535 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01273637 0,07185901 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01273637 0,07169343 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01273637 0,07152862 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01273637 0,07136456 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01273637 0,07120126 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01273637 0,0710387 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01273637 0,07087688 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01273637 0,0707158 ! response to arsenic GO:0046685 11 5 0,000 0,01273637 0,07055544 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01273637 0,07039582 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01273637 0,07023691 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01273637 0,07007872 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01273637 0,06992124 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01273637 0,06976446 ! response to mercury ion GO:0046689 8 5 0,000 0,01273637 0,06960839 ! response to cadmium ion GO:0046686 7 5 0,000 0,01273637 0,06945301 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01273637 0,06929833 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01273637 0,06914433 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01273637 0,06899102 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01273637 0,06883839 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01273637 0,06868642 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01273637 0,06853513 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01273637 0,06838451 ! decidualization GO:0046697 11 5 0,000 0,01273637 0,06823454 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01273637 0,06808523 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01273637 0,06793657 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01273637 0,06778856 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01273637 0,0676412 ! embryonic cleavage GO:0040016 6 5 0,000 0,01273637 0,06749447 ! peroxisome fission GO:0016559 5 5 0,000 0,01273637 0,06734838 ! histone demethylation GO:0016577 13 5 0,000 0,01273637 0,06720292 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01273637 0,06705808 ! mitotic recombination GO:0006312 9 5 0,000 0,01273637 0,06691387 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01273637 0,06677028 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01273637 0,0666273 ! metaphase plate congression GO:0051310 7 5 0,000 0,01273637 0,06648494 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01273637 0,06634318 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,01273637 0,06620202 ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01273637 0,06606147 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01273637 0,0659215 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01273637 0,06578214 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01273637 0,06564336 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01273637 0,06550516 ! B cell homeostasis GO:0001782 13 5 0,000 0,01273637 0,06536754 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01273637 0,0652305 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01273637 0,06509404 ! metaphase GO:0051323 11 5 0,000 0,01273637 0,06495814 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01273637 0,06482281 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01273637 0,06468805 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01273637 0,06455384 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01273637 0,06442019 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01273637 0,06428709 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01273637 0,06415454 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01273637 0,06402253 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01273637 0,06389107 ! response to redox state GO:0051775 6 5 0,000 0,01273637 0,06376014 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01273637 0,06362976 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01273637 0,0634999 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01273637 0,06337057 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01273637 0,06324177 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01273637 0,06311349 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01273637 0,06298573 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01273637 0,06285849 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01273637 0,06273175 ! striatum development GO:0021756 14 5 0,000 0,01273637 0,06260553 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01273637 0,06247982 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01273637 0,06235461 ! glial cell migration GO:0008347 10 5 0,000 0,01273637 0,0622299 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01273637 0,06210569 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01273637 0,06198197 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01273637 0,06185875 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01273637 0,06173601 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01273637 0,06161376 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01273637 0,061492 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01273637 0,06137071 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01273637 0,0612499 ! neuroprotection GO:0043526 8 5 0,000 0,01273637 0,06112957 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01273637 0,06100971 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01273637 0,06089031 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01273637 0,06077139 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01273637 0,06065292 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01273637 0,06053492 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01273637 0,06041738 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01273637 0,06030029 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01273637 0,06018366 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01273637 0,06006747 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01273637 0,05995173 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01273637 0,05983644 ! spindle assembly GO:0051225 6 5 0,000 0,01273637 0,05972159 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01273637 0,05960718 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01273637 0,05949321 ! protein palmitoylation GO:0018345 12 5 0,000 0,01273637 0,05937968 ! drug metabolic process GO:0017144 7 5 0,000 0,01273637 0,05926657 ! stem cell division GO:0017145 11 5 0,000 0,01273637 0,0591539 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01273637 0,05904165 ! organ regeneration GO:0031100 7 5 0,000 0,01273637 0,05892983 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01273637 0,05881843 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01273637 0,05870745 ! secondary metabolic process GO:0019748 125 67 1,000 0,01286691 0,05919748 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,01286691 0,0590862 ! regulation of lipase activity GO:0060191 137 68 1,000 0,01323496 0,0606623 ! adaptive immune response GO:0002250 126 68 1,000 0,01323496 0,0605487 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! homeostasis of number of cells GO:0048872 131 69 1,000 0,01360757 0,06213698 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,01360757 0,06202105 ! cellular amino acid catabolic process GO:0009063 120 69 1,000 0,01360757 0,06190556 ! germ cell development GO:0007281 133 70 1,000 0,0139847 0,06350303 ! cell cycle checkpoint GO:0000075 145 71 1,000 0,01436635 0,065115 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,01436635 0,06499442 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01526432 0,06892929 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01526432 0,06880211 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01526432 0,0686754 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01526432 0,06854916 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01526432 0,06842338 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01526432 0,06829807 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01526432 0,06817321 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01526432 0,0680488 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01526432 0,06792485 ! response to oxygen radical GO:0000305 11 6 0,000 0,01526432 0,06780135 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01526432 0,0676783 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01526432 0,0675557 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01526432 0,06743353 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01526432 0,06731181 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01526432 0,06719053 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01526432 0,06706968 ! forebrain regionalization GO:0021871 9 6 0,000 0,01526432 0,06694927 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01526432 0,06682929 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01526432 0,06670974 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01526432 0,06659061 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01526432 0,06647191 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01526432 0,06635364 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01526432 0,06623578 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01526432 0,06611834 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01526432 0,06600132 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01526432 0,06588471 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01526432 0,06576851 ! malate metabolic process GO:0006108 13 6 0,000 0,01526432 0,06565272 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01526432 0,06553734 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01526432 0,06542236 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01526432 0,06530778 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01526432 0,06519361 ! protein refolding GO:0042026 15 6 0,000 0,01526432 0,06507983 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01526432 0,06496645 ! opsonization GO:0008228 8 6 0,000 0,01526432 0,06485347 ! mating behavior GO:0007617 7 6 0,000 0,01526432 0,06474088 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01526432 0,06462867 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01526432 0,06451686 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01526432 0,06440543 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01526432 0,06429439 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01526432 0,06418372 ! toxin metabolic process GO:0009404 11 6 0,000 0,01526432 0,06407344 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01526432 0,06396354 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01526432 0,06385401 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01526432 0,06374486 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01526432 0,06363608 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01526432 0,06352767 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01526432 0,06341963 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01526432 0,06331196 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01526432 0,06320465 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01526432 0,06309771 ! thymic T cell selection GO:0045061 16 6 0,000 0,01526432 0,06299112 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01526432 0,0628849 ! protein lipoylation GO:0009249 10 6 0,000 0,01526432 0,06277903 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01526432 0,06267352 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01526432 0,06256836 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01526432 0,06246356 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01526432 0,0623591 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01526432 0,062255 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01526432 0,06215124 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01526432 0,06204783 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01526432 0,06194476 ! hyperosmotic response GO:0006972 10 6 0,000 0,01526432 0,06184203 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01526432 0,06173964 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01526432 0,06163759 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01526432 0,06153588 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01526432 0,0614345 ! urea metabolic process GO:0019627 7 6 0,000 0,01526432 0,06133346 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01526432 0,06123275 ! neutrophil activation GO:0042119 7 6 0,000 0,01526432 0,06113237 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01526432 0,06103231 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01526432 0,06093259 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01526432 0,06083319 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01526432 0,06073411 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01526432 0,06063536 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01526432 0,06053692 ! neuron apoptosis GO:0051402 15 6 0,000 0,01526432 0,06043881 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01526432 0,06034101 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01526432 0,06024353 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01526432 0,06014636 ! carnitine transport GO:0015879 10 6 0,000 0,01526432 0,06004951 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01526432 0,05995296 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01526432 0,05985673 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01526432 0,05976081 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01526432 0,05966519 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01526432 0,05956988 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01526432 0,05947487 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01526432 0,05938017 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01526432 0,05928576 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01526432 0,05919166 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01526432 0,05909785 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01526432 0,05900434 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01526432 0,05891113 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01526432 0,05881821 ! response to UV-C GO:0010225 14 6 0,000 0,01526432 0,05872558 ! astrocyte development GO:0014002 16 6 0,000 0,01526432 0,05863325 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01526432 0,0585412 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01526432 0,05844944 ! interaction with symbiont GO:0051702 14 6 0,000 0,01526432 0,05835797 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01526432 0,05826679 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01526432 0,05817589 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01526432 0,05808527 ! response to copper ion GO:0046688 10 6 0,000 0,01526432 0,05799494 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01526432 0,05790488 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01526432 0,05781511 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01526432 0,05772561 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01526432 0,05763639 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01526432 0,05754744 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01526432 0,05745877 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01526432 0,05737038 ! hair follicle maturation GO:0048820 8 6 0,000 0,01526432 0,05728225 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01526432 0,05719439 ! Schwann cell development GO:0014044 15 6 0,000 0,01526432 0,05710681 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01526432 0,05701949 ! response to pheromone GO:0019236 6 6 0,000 0,01526432 0,05693243 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01526432 0,05684565 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01526432 0,05675912 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01526432 0,05667286 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01526432 0,05658687 ! subpallium development GO:0021544 15 6 0,000 0,01526432 0,05650113 ! neural tube patterning GO:0021532 8 6 0,000 0,01526432 0,05641565 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01526432 0,05633043 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01526432 0,05624547 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01526432 0,05616076 ! G2 phase GO:0051319 16 6 0,000 0,01526432 0,05607631 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01526432 0,05599211 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01526432 0,05590816 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01526432 0,05582447 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01526432 0,05574102 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01526432 0,05565783 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01526432 0,05557488 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01526432 0,05549218 ! receptor internalization GO:0031623 11 6 0,000 0,01526432 0,05540972 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01526432 0,05532751 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01526432 0,05524555 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01526432 0,05516382 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01526432 0,05508234 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01526432 0,0550011 ! protein deubiquitination GO:0016579 16 6 0,000 0,01526432 0,05492009 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01526432 0,05483933 ! protein destabilization GO:0031648 9 6 0,000 0,01526432 0,0547588 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01526432 0,05467851 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01526432 0,05459845 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01526432 0,05451863 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01526432 0,05443904 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01526432 0,05435969 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01526432 0,05428056 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01526432 0,05420166 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01526432 0,054123 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01526432 0,05404456 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01526432 0,05396634 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01526432 0,05388836 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01526432 0,0538106 ! neural plate development GO:0001840 9 6 0,000 0,01526432 0,05373306 ! catecholamine transport GO:0051937 9 6 0,000 0,01526432 0,05365575 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01526432 0,05357866 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01526432 0,05350179 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01526432 0,05342513 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01526432 0,0533487 ! maternal placenta development GO:0001893 12 6 0,000 0,01526432 0,05327249 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01526432 0,0531965 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01526432 0,05312072 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01526432 0,05304516 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01526432 0,05296981 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01526432 0,05289467 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01526432 0,05281975 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01526432 0,05274504 GO:0055081|anion homeostasis, ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,01593748 0,0549933 GO:0090046|regulation of transcription regulator activity, ! cell-matrix adhesion GO:0007160 181 76 1,000 0,01634128 0,05630711 ! amine catabolic process GO:0009310 136 77 1,000 0,01674943 0,05763221 ! regulation of catabolic process GO:0009894 173 77 1,000 0,01674943 0,05755115 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,01716192 0,05888564 ! tRNA transcription GO:0009304 17 7 0,000 0,01778588 0,06094095 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01778588 0,0608556 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01778588 0,06077049 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01778588 0,06068561 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01778588 0,06060097 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01778588 0,06051657 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01778588 0,0604324 ! sleep GO:0030431 16 7 0,000 0,01778588 0,06034847 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01778588 0,06026477 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01778588 0,0601813 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01778588 0,06009806 ! prostate gland development GO:0030850 14 7 0,000 0,01778588 0,06001505 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01778588 0,05993227 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01778588 0,05984972 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01778588 0,0597674 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01778588 0,0596853 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01778588 0,05960343 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01778588 0,05952178 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01778588 0,05944035 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01778588 0,05935915 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01778588 0,05927817 ! glycolipid transport GO:0046836 11 7 0,000 0,01778588 0,05919741 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01778588 0,05911687 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,01778588 0,05903655 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01778588 0,05895644 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01778588 0,05887656 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01778588 0,05879688 ! pericardium development GO:0060039 16 7 0,000 0,01778588 0,05871743 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01778588 0,05863819 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01778588 0,05855916 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01778588 0,05848035 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01778588 0,05840174 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01778588 0,05832335 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01778588 0,05824517 ! lipoprotein transport GO:0042953 14 7 0,000 0,01778588 0,0581672 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01778588 0,05808944 ! rhythmic behavior GO:0007622 17 7 0,000 0,01778588 0,05801188 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01778588 0,05793453 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01778588 0,05785739 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01778588 0,05778045 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01778588 0,05770372 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01778588 0,05762719 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01778588 0,05755086 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01778588 0,05747473 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01778588 0,05739881 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01778588 0,05732308 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01778588 0,05724756 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01778588 0,05717223 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01778588 0,05709711 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01778588 0,05702218 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01778588 0,05694744 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01778588 0,0568729 ! spinal cord patterning GO:0021511 14 7 0,000 0,01778588 0,05679856 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01778588 0,05672441 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01778588 0,05665045 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01778588 0,05657669 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01778588 0,05650312 ! adrenal gland development GO:0030325 17 7 0,000 0,01778588 0,05642974 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01778588 0,05635655 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01778588 0,05628355 ! ovulation GO:0030728 10 7 0,000 0,01778588 0,05621073 ! adenohypophysis development GO:0021984 11 7 0,000 0,01778588 0,05613811 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01778588 0,05606567 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01778588 0,05599343 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01778588 0,05592136 ! microtubule nucleation GO:0007020 21 7 0,000 0,01778588 0,05584948 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01778588 0,05577779 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01778588 0,05570628 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01778588 0,05563495 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01778588 0,05556381 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01778588 0,05549285 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01778588 0,05542206 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01778588 0,05535146 ! galactose metabolic process GO:0006012 13 7 0,000 0,01778588 0,05528104 ! vesicle fusion GO:0006906 20 7 0,000 0,01778588 0,0552108 ! response to dietary excess GO:0002021 8 7 0,000 0,01778588 0,05514073 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01778588 0,05507085 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01778588 0,05500114 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01778588 0,0549316 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01778588 0,05486224 ! organ growth GO:0035265 15 7 0,000 0,01778588 0,05479306 ! nucleoside transport GO:0015858 11 7 0,000 0,01778588 0,05472405 ! nucleoside salvage GO:0043174 11 7 0,000 0,01778588 0,05465522 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01778588 0,05458656 ! male sex determination GO:0030238 15 7 0,000 0,01778588 0,05451807 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01778588 0,05444975 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01778588 0,0543816 ! parturition GO:0007567 16 7 0,000 0,01778588 0,05431362 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01778588 0,05424582 ! rRNA modification GO:0000154 14 7 0,000 0,01778588 0,05417818 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01778588 0,05411071 ! spindle checkpoint GO:0031577 16 7 0,000 0,01778588 0,05404341 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01778588 0,05397627 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01778588 0,0539093 ! monocyte differentiation GO:0030224 16 7 0,000 0,01778588 0,0538425 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01778588 0,05377586 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01778588 0,05370939 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01778588 0,05364308 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01778588 0,05357694 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01778588 0,05351096 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01778588 0,05344514 ! fibrinolysis GO:0042730 11 7 0,000 0,01778588 0,05337948 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01778588 0,05331399 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01778588 0,05324865 ! eating behavior GO:0042755 8 7 0,000 0,01778588 0,05318347 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01778588 0,05311846 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01778588 0,0530536 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01778588 0,0529889 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01778588 0,05292436 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01778588 0,05285997 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01778588 0,05279574 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01778588 0,05273167 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01778588 0,05266776 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01778588 0,05260399 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01778588 0,05254038 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01778588 0,05247693 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01778588 0,05241363 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01778588 0,05235048 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01778588 0,05228748 ! histone ubiquitination GO:0016574 9 7 0,000 0,01778588 0,05222464 ! regulation of meiosis GO:0040020 12 7 0,000 0,01778588 0,05216194 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01778588 0,0520994 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01778588 0,052037 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01778588 0,05197476 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01778588 0,05191266 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01778588 0,05185071 ! transcription termination GO:0006353 14 7 0,000 0,01778588 0,05178891 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01778588 0,05172726 ! anaphase GO:0051322 18 7 0,000 0,01778588 0,05166575 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01778588 0,05160439 ! axonal fasciculation GO:0007413 19 7 0,000 0,01778588 0,05154318 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01778588 0,05148211 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01778588 0,05142118 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01778588 0,0513604 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01778588 0,05129976 ! diuresis GO:0030146 12 7 0,000 0,01778588 0,05123927 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01778588 0,05117891 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01778588 0,0511187 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01778588 0,05105863 ! antibiotic transport GO:0042891 9 7 0,000 0,01778588 0,05099871 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01778588 0,05093892 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01778588 0,05087927 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01778588 0,05081976 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01778588 0,05076039 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01778588 0,05070116 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01778588 0,05064207 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01778588 0,05058312 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01778588 0,0505243 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01778588 0,05046562 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01778588 0,05040707 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01778588 0,05034866 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01778588 0,05029039 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01778588 0,05023225 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01778588 0,05017425 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01778588 0,05011638 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01778588 0,05005864 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01778588 0,05000103 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01778588 0,04994356 ! muscle adaptation GO:0043500 13 7 0,000 0,01778588 0,04988622 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01778588 0,04982901 ! retina homeostasis GO:0001895 12 7 0,000 0,01778588 0,04977193 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01778588 0,04971499 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01778588 0,04965817 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01778588 0,04960148 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01778588 0,04954492 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,0179998 0,05008373 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,01842514 0,0512089 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,01885472 0,05234328 ! protein import into nucleus GO:0006606 174 82 1,000 0,01885472 0,05228386 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,01928851 0,05342611 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 1,000 0,01928851 0,05336561 ! response to nutrient GO:0007584 135 84 1,000 0,01972649 0,05451562 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,02016863 0,05567454 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02030104 0,05597681 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02030104 0,0559137 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,02030104 0,05585073 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,02030104 0,05578791 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02030104 0,05572523 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02030104 0,05566268 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02030104 0,05560028 ! male meiosis GO:0007140 9 8 0,000 0,02030104 0,05553802 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02030104 0,0554759 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02030104 0,05541391 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,02030104 0,05535207 ! meiotic prophase I GO:0007128 14 8 0,000 0,02030104 0,05529036 ! response to zinc ion GO:0010043 12 8 0,000 0,02030104 0,05522879 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02030104 0,05516735 ! oligopeptide transport GO:0006857 16 8 0,000 0,02030104 0,05510606 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02030104 0,0550449 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02030104 0,05498387 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02030104 0,05492298 ! signal peptide processing GO:0006465 12 8 0,000 0,02030104 0,05486222 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,02030104 0,0548016 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02030104 0,05474112 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02030104 0,05468076 ! succinate metabolic process GO:0006105 17 8 0,000 0,02030104 0,05462054 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02030104 0,05456045 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02030104 0,0545005 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02030104 0,05444067 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02030104 0,05438098 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02030104 0,05432141 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02030104 0,05426198 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02030104 0,05420268 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02030104 0,0541435 ! reflex GO:0060004 17 8 0,000 0,02030104 0,05408446 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02030104 0,05402555 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,02030104 0,05396676 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02030104 0,0539081 ! pigment granule organization GO:0048753 17 8 0,000 0,02030104 0,05384957 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02030104 0,05379116 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02030104 0,05373288 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02030104 0,05367473 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02030104 0,0536167 ! histidine catabolic process GO:0006548 10 8 0,000 0,02030104 0,0535588 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02030104 0,05350103 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02030104 0,05344337 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02030104 0,05338585 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02030104 0,05332844 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,02030104 0,05327116 ! melanin metabolic process GO:0006582 17 8 0,000 0,02030104 0,053214 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02030104 0,05315697 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02030104 0,05310005 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02030104 0,05304326 ! macrophage activation GO:0042116 13 8 0,000 0,02030104 0,05298659 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02030104 0,05293004 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02030104 0,05287361 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,02030104 0,05281731 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02030104 0,05276112 ! purine salvage GO:0043101 12 8 0,000 0,02030104 0,05270505 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02030104 0,0526491 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,02030104 0,05259327 ! osteoblast development GO:0002076 17 8 0,000 0,02030104 0,05253755 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02030104 0,05248196 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,02030104 0,05242648 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02030104 0,05237112 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02030104 0,05231588 ! response to UV-B GO:0010224 17 8 0,000 0,02030104 0,05226075 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02030104 0,05220574 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02030104 0,05215084 ! intermediate filament organization GO:0045109 12 8 0,000 0,02030104 0,05209606 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,02030104 0,0520414 ! cellular extravasation GO:0045123 13 8 0,000 0,02030104 0,05198685 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02030104 0,05193241 ! response to antibiotic GO:0046677 11 8 0,000 0,02030104 0,05187809 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02030104 0,05182388 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02030104 0,05176978 ! DNA topological change GO:0006265 12 8 0,000 0,02030104 0,0517158 ! response to tropane GO:0014073 15 8 0,000 0,02030104 0,05166193 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,02030104 0,05160817 ! melanosome transport GO:0032402 13 8 0,000 0,02030104 0,05155452 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 0,02030104 0,05150099 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02030104 0,05144756 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02030104 0,05139425 ! mast cell activation GO:0045576 14 8 0,000 0,02030104 0,05134105 ! multicellular organismal aging GO:0010259 20 8 0,000 0,02030104 0,05128795 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,02030104 0,05123497 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02030104 0,0511821 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02030104 0,05112933 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02030104 0,05107667 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02030104 0,05102413 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02030104 0,05097169 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,02030104 0,05091935 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02030104 0,05086713 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02030104 0,05081501 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02030104 0,050763 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02030104 0,05071109 ! response to tumor cell GO:0002347 16 8 0,000 0,02030104 0,0506593 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02030104 0,0506076 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,02030104 0,05055601 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,02030104 0,05050453 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,02030104 0,05045315 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02030104 0,05040188 ! hormone catabolic process GO:0042447 17 8 0,000 0,02030104 0,05035071 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02030104 0,05029965 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02030104 0,05024868 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,02030104 0,05019782 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02030104 0,05014707 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02030104 0,05009641 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,02030104 0,05004586 ! adult feeding behavior GO:0008343 10 8 0,000 0,02030104 0,04999541 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02030104 0,04994507 ! ATP catabolic process GO:0006200 11 8 0,000 0,02030104 0,04989482 ! blastocyst growth GO:0001832 19 8 0,000 0,02030104 0,04984467 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02030104 0,04979463 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02030104 0,04974468 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02030104 0,04969484 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02030104 0,0496451 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02030104 0,04959545 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,02030104 0,0495459 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02030104 0,04949646 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02030104 0,04944711 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02030104 0,04939786 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02030104 0,04934871 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02030104 0,04929965 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,02030104 0,0492507 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02030104 0,04920184 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02030104 0,04915307 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,02030104 0,04910441 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,02030104 0,04905584 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,02030104 0,04900736 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,02030104 0,04895898 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,02061491 0,0496669 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein transport GO:0051223 165 87 1,000 0,02106531 0,05070203 GO:0070201|regulation of establishment of protein localization, ! protein localization in nucleus GO:0034504 192 89 1,000 0,02197837 0,0528476 ! axon extension GO:0048675 16 9 0,000 0,02280984 0,05479296 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02280984 0,05473914 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,02280984 0,05468542 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02280984 0,05463181 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02280984 0,0545783 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02280984 0,05452489 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02280984 0,05447159 ! reproductive behavior GO:0019098 22 9 0,000 0,02280984 0,0544184 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02280984 0,05436531 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02280984 0,05431232 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02280984 0,05425944 ! RNA methylation GO:0001510 16 9 0,000 0,02280984 0,05420665 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02280984 0,05415398 ! artery development GO:0060840 25 9 0,000 0,02280984 0,0541014 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02280984 0,05404892 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02280984 0,05399655 ! equilibrioception GO:0050957 20 9 0,000 0,02280984 0,05394428 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02280984 0,05389211 ! chemosensory behavior GO:0007635 21 9 0,000 0,02280984 0,05384004 ! microtubule bundle formation GO:0001578 22 9 0,000 0,02280984 0,05378807 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02280984 0,0537362 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02280984 0,05368443 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02280984 0,05363276 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02280984 0,05358119 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02280984 0,05352972 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02280984 0,05347835 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02280984 0,05342708 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02280984 0,0533759 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02280984 0,05332482 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02280984 0,05327384 ! protein targeting to ER GO:0045047 25 9 0,000 0,02280984 0,05322296 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02280984 0,05317218 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02280984 0,05312149 ! T cell selection GO:0045058 27 9 0,000 0,02280984 0,0530709 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,02280984 0,0530204 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02280984 0,05297 ! glycine catabolic process GO:0006546 15 9 0,000 0,02280984 0,0529197 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02280984 0,05286949 ! endosome organization GO:0007032 20 9 0,000 0,02280984 0,05281938 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02280984 0,05276936 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,02280984 0,05271943 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02280984 0,0526696 ! mannose metabolic process GO:0006013 13 9 0,000 0,02280984 0,05261987 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02280984 0,05257023 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02280984 0,05252068 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,02280984 0,05247123 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02280984 0,05242186 ! receptor clustering GO:0043113 20 9 0,000 0,02280984 0,0523726 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02280984 0,05232342 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02280984 0,05227434 ! retinol metabolic process GO:0042572 20 9 0,000 0,02280984 0,05222534 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02280984 0,05217644 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02280984 0,05212763 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02280984 0,05207892 ! macrophage differentiation GO:0030225 15 9 0,000 0,02280984 0,05203029 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02280984 0,05198175 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02280984 0,05193331 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02280984 0,05188495 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02280984 0,05183669 ! response to amine stimulus GO:0014075 13 9 0,000 0,02280984 0,05178851 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02280984 0,05174043 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02280984 0,05169243 ! erythrocyte development GO:0048821 17 9 0,000 0,02280984 0,05164452 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02280984 0,0515967 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02280984 0,05154897 ! renal water homeostasis GO:0003091 15 9 0,000 0,02280984 0,05150133 ! postreplication repair GO:0006301 25 9 0,000 0,02280984 0,05145378 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02280984 0,05140631 ! icosanoid secretion GO:0032309 15 9 0,000 0,02280984 0,05135893 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02280984 0,05131164 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02280984 0,05126444 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02280984 0,05121732 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02280984 0,05117029 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02280984 0,05112334 ! sterol catabolic process GO:0016127 14 9 0,000 0,02280984 0,05107648 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02280984 0,05102971 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02280984 0,05098302 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02280984 0,05093642 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02280984 0,0508899 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,02280984 0,05084347 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02280984 0,05079712 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02280984 0,05075086 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02280984 0,05070468 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02280984 0,05065858 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02280984 0,05061257 ! purine base metabolic process GO:0006144 25 9 0,000 0,02280984 0,05056664 ! pigment granule transport GO:0051904 17 9 0,000 0,02280984 0,0505208 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,02280984 0,05047504 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02280984 0,05042936 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02280984 0,05038376 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02280984 0,05033825 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02280984 0,05029282 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02280984 0,05024747 ! mitochondrion localization GO:0051646 18 9 0,000 0,02280984 0,0502022 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,02385286 0,05245053 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,02385286 0,05240336 ! nitrogen compound catabolic process GO:0044270 167 94 1,000 0,02433143 0,05340671 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,02481392 0,05441689 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,02531228 0,05546001 ! regulation of developmental growth GO:0048638 16 10 0,000 0,02531228 0,05541031 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02531228 0,05536071 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02531228 0,05531119 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02531228 0,05526176 ! associative learning GO:0008306 21 10 0,000 0,02531228 0,05521242 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02531228 0,05516317 ! phosphate transport GO:0006817 24 10 0,000 0,02531228 0,055114 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02531228 0,05506492 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02531228 0,05501593 ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,02531228 0,05496703 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02531228 0,05491821 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,02531228 0,05486948 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,02531228 0,05482084 ! social behavior GO:0035176 29 10 0,000 0,02531228 0,05477228 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02531228 0,05472381 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02531228 0,05467543 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02531228 0,05462713 ! androgen metabolic process GO:0008209 17 10 0,000 0,02531228 0,05457891 ! phospholipid efflux GO:0033700 19 10 0,000 0,02531228 0,05453078 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02531228 0,05448274 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02531228 0,05443478 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,02531228 0,0543869 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02531228 0,05433911 ! pathogenesis GO:0009405 17 10 0,000 0,02531228 0,0542914 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02531228 0,05424378 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02531228 0,05419624 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02531228 0,05414878 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02531228 0,05410141 ! endoderm development GO:0007492 18 10 0,000 0,02531228 0,05405412 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02531228 0,05400691 ! arginine catabolic process GO:0006527 17 10 0,000 0,02531228 0,05395978 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02531228 0,05391274 ! proline metabolic process GO:0006560 13 10 0,000 0,02531228 0,05386577 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02531228 0,05381889 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02531228 0,05377209 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02531228 0,05372538 ! V(D)J recombination GO:0033151 34 10 0,000 0,02531228 0,05367874 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02531228 0,05363218 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02531228 0,05358571 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02531228 0,05353932 ! B cell proliferation GO:0042100 19 10 0,000 0,02531228 0,053493 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02531228 0,05344677 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02531228 0,05340061 ! multicellular organism growth GO:0035264 19 10 0,000 0,02531228 0,05335454 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02531228 0,05330854 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02531228 0,05326263 ! ruffle organization GO:0031529 17 10 0,000 0,02531228 0,05321679 ! epithelial cell development GO:0002064 21 10 0,000 0,02531228 0,05317103 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02531228 0,05312535 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02531228 0,05307975 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02531228 0,05303423 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02531228 0,05298878 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02531228 0,05294342 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,02531228 0,05289813 ! motor axon guidance GO:0008045 22 10 0,000 0,02531228 0,05285291 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02531228 0,05280778 ! protein heterooligomerization GO:0051291 17 10 0,000 0,02531228 0,05276272 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02531228 0,05271774 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02531228 0,05267284 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02531228 0,05262801 ! segment specification GO:0007379 15 10 0,000 0,02531228 0,05258326 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,02531228 0,05253858 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,02531228 0,05249398 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02531228 0,05244946 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02531228 0,05240501 ! response to dsRNA GO:0043331 23 10 0,000 0,02531228 0,05236063 ! DNA ligation GO:0006266 18 10 0,000 0,02531228 0,05231634 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02531228 0,05227211 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02531228 0,05222796 ! melanosome localization GO:0032400 16 10 0,000 0,02531228 0,05218389 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02531228 0,05213989 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,02531228 0,05209596 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02531228 0,05205211 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02531228 0,05200833 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02531228 0,05196463 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02531228 0,051921 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02531228 0,05187744 ! protein sumoylation GO:0016925 17 10 0,000 0,02531228 0,05183396 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02531228 0,05179054 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02531228 0,0517472 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02531228 0,05170394 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02531228 0,05166074 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02531228 0,05161762 ! salivary gland development GO:0007431 28 10 0,000 0,02531228 0,05157457 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02531228 0,05153159 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,02531228 0,05148868 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02531228 0,05144585 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02531228 0,05140308 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02531228 0,05136039 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,02531228 0,05131777 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02531228 0,05127521 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02531228 0,05123273 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02531228 0,05119032 ! detection of calcium ion GO:0005513 24 10 0,000 0,02531228 0,05114798 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02531228 0,05110571 ! blastocyst formation GO:0001825 18 10 0,000 0,02531228 0,05106351 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02531228 0,05102138 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02531228 0,05097931 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02531228 0,05093732 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02531228 0,0508954 ! response to nicotine GO:0035094 20 10 0,000 0,02531228 0,05085354 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02531228 0,05081176 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,02579062 0,05172946 ! regulation of protein localization GO:0032880 188 97 1,000 0,02579062 0,05168703 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02780839 0,05568516 ! respiratory burst GO:0045730 17 11 0,000 0,02780839 0,05563955 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02780839 0,05559402 ! neuron fate specification GO:0048665 18 11 0,000 0,02780839 0,05554856 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02780839 0,05550318 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02780839 0,05545787 ! thyroid gland development GO:0030878 26 11 0,000 0,02780839 0,05541264 ! synapsis GO:0007129 14 11 0,000 0,02780839 0,05536748 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02780839 0,05532239 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,02780839 0,05527737 ! response to pain GO:0048265 27 11 0,000 0,02780839 0,05523243 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02780839 0,05518757 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02780839 0,05514277 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02780839 0,05509805 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,02780839 0,0550534 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02780839 0,05500882 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02780839 0,05496431 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02780839 0,05491988 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02780839 0,05487552 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02780839 0,05483123 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,02780839 0,05478701 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02780839 0,05474286 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02780839 0,05469879 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,02780839 0,05465478 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,02780839 0,05461085 ! UV protection GO:0009650 20 11 0,000 0,02780839 0,05456698 ! adult heart development GO:0007512 16 11 0,000 0,02780839 0,05452319 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,02780839 0,05447946 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02780839 0,05443581 ! macroautophagy GO:0016236 19 11 0,000 0,02780839 0,05439223 ! temperature homeostasis GO:0001659 18 11 0,000 0,02780839 0,05434871 ! behavioral fear response GO:0001662 27 11 0,000 0,02780839 0,05430527 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02780839 0,0542619 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02780839 0,05421859 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02780839 0,05417535 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,02780839 0,05413219 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02780839 0,05408909 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02780839 0,05404606 ! regulation of organ growth GO:0046620 14 11 0,000 0,02780839 0,05400309 ! pigment granule localization GO:0051875 20 11 0,000 0,02780839 0,0539602 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02780839 0,05391738 ! vasoconstriction GO:0042310 20 11 0,000 0,02780839 0,05387462 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02780839 0,05383193 ! embryonic axis specification GO:0000578 19 11 0,000 0,02780839 0,05378931 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02780839 0,05374675 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02780839 0,05370426 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02780839 0,05366184 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02780839 0,05361949 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02780839 0,0535772 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02780839 0,05353498 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02780839 0,05349283 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02780839 0,05345074 ! prophase GO:0051324 17 11 0,000 0,02780839 0,05340872 ! neuroblast proliferation GO:0007405 25 11 0,000 0,02780839 0,05336677 ! nucleosome positioning GO:0016584 15 11 0,000 0,02780839 0,05332488 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02780839 0,05328305 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02780839 0,0532413 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02780839 0,0531996 ! apical protein localization GO:0045176 18 11 0,000 0,02780839 0,05315798 ! acid secretion GO:0046717 20 11 0,000 0,02780839 0,05311641 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02780839 0,05307492 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,02780839 0,05303348 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02780839 0,05299212 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,02780839 0,05295081 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02780839 0,05290957 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,02780839 0,0528684 ! cholesterol efflux GO:0033344 21 11 0,000 0,02780839 0,05282729 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02780839 0,05278624 ! oocyte development GO:0048599 20 11 0,000 0,02780839 0,05274526 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,02780839 0,05270434 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,02780839 0,05266348 ! embryonic gut development GO:0048566 19 11 0,000 0,02780839 0,05262269 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02780839 0,05258196 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02780839 0,05254129 ! activation of innate immune response GO:0002218 16 11 0,000 0,02780839 0,05250069 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02780839 0,05246015 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,02780839 0,05241967 ! lysogeny GO:0030069 22 11 0,000 0,02780839 0,05237925 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02780839 0,0523389 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,02780839 0,05229861 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02780839 0,05225838 ! regulation of embryonic development GO:0045995 35 11 0,000 0,02780839 0,05221821 ! nucleus localization GO:0051647 22 11 0,000 0,02780839 0,0521781 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,03029817 0,05680616 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,03029817 0,0567626 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,03029817 0,0567191 ! virus-host interaction GO:0019048 30 12 0,000 0,03029817 0,05667567 ! mating GO:0007618 17 12 0,000 0,03029817 0,05663231 ! protein complex disassembly GO:0043241 28 12 0,000 0,03029817 0,05658901 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03029817 0,05654578 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,03029817 0,05650262 ! hippocampus development GO:0021766 29 12 0,000 0,03029817 0,05645952 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,03029817 0,05641649 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,03029817 0,05637352 ! T cell proliferation GO:0042098 32 12 0,000 0,03029817 0,05633062 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03029817 0,05628778 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,03029817 0,05624501 ! ventral spinal cord development GO:0021517 25 12 0,000 0,03029817 0,0562023 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,03029817 0,05615966 ! drug transport GO:0015893 16 12 0,000 0,03029817 0,05611708 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,03029817 0,05607457 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,03029817 0,05603212 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,03029817 0,05598974 ! polyamine metabolic process GO:0006595 18 12 0,000 0,03029817 0,05594742 ! focal adhesion formation GO:0048041 37 12 0,000 0,03029817 0,05590516 ! mitotic spindle organization GO:0007052 23 12 0,000 0,03029817 0,05586297 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,03029817 0,05582084 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,03029817 0,05577877 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,03029817 0,05573677 ! lipid digestion GO:0044241 21 12 0,000 0,03029817 0,05569483 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,03029817 0,05565296 ! entry into host cell GO:0030260 34 12 0,000 0,03029817 0,05561114 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03029817 0,05556939 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,03029817 0,05552771 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,03029817 0,05548608 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03029817 0,05544452 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,03029817 0,05540302 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,03029817 0,05536158 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,03029817 0,0553202 ! snRNA metabolic process GO:0016073 30 12 0,000 0,03029817 0,05527889 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,03029817 0,05523764 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,03029817 0,05519644 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03029817 0,05515531 ! cranial nerve development GO:0021545 23 12 0,000 0,03029817 0,05511424 ! fucose catabolic process GO:0019317 25 12 0,000 0,03029817 0,05507324 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,03029817 0,05503229 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,03029817 0,0549914 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03029817 0,05495058 ! zymogen activation GO:0031638 18 12 0,000 0,03029817 0,05490982 ! T cell homeostasis GO:0043029 28 12 0,000 0,03029817 0,05486911 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,03029817 0,05482847 ! oocyte differentiation GO:0009994 21 12 0,000 0,03029817 0,05478788 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,03029817 0,05474736 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,03029817 0,0547069 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,03029817 0,05466649 GO:0042130|negative regulation of T cell proliferation, ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,03029817 0,05462615 ! defense response to fungus GO:0050832 15 12 0,000 0,03029817 0,05458586 ! lamellipodium assembly GO:0030032 24 12 0,000 0,03029817 0,05454564 ! response to cold GO:0009409 17 12 0,000 0,03029817 0,05450547 ! establishment of cell polarity GO:0030010 21 12 0,000 0,03029817 0,05446536 ! regulation of synapse organization GO:0050807 18 12 0,000 0,03029817 0,05442532 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,03278165 0,05884318 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03278165 0,05879997 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,03278165 0,05875683 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03278165 0,05871376 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,03278165 0,05867074 ! peroxisomal transport GO:0043574 28 13 0,000 0,03278165 0,05862779 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,03278165 0,0585849 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,03278165 0,05854208 ! organelle fusion GO:0048284 36 13 0,000 0,03278165 0,05849932 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,03278165 0,05845662 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,03278165 0,05841398 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,03278165 0,0583714 ! endocrine pancreas development GO:0031018 25 13 0,000 0,03278165 0,05832889 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,03278165 0,05828644 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,03278165 0,05824405 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,03278165 0,05820172 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,03278165 0,05815945 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,03278165 0,05811724 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03278165 0,0580751 ! methionine metabolic process GO:0006555 31 13 0,000 0,03278165 0,05803302 ! plasma membrane organization GO:0007009 27 13 0,000 0,03278165 0,05799099 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,03278165 0,05794903 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,03278165 0,05790713 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,03278165 0,05786529 ! response to X-ray GO:0010165 28 13 0,000 0,03278165 0,05782351 ! cytokine metabolic process GO:0042107 24 13 0,000 0,03278165 0,05778179 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,03278165 0,05774013 ! exocrine system development GO:0035272 34 13 0,000 0,03278165 0,05769853 ! asymmetric protein localization GO:0008105 24 13 0,000 0,03278165 0,05765699 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,03278165 0,05761551 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,03278165 0,05757409 ! L-glutamate transport GO:0015813 30 13 0,000 0,03278165 0,05753273 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,03278165 0,05749143 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,03278165 0,05745019 ! protein homotetramerization GO:0051289 24 13 0,000 0,03278165 0,05740901 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,03278165 0,05736788 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,03278165 0,05732682 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,03278165 0,05728581 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,03278165 0,05724486 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03278165 0,05720397 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,03278165 0,05716314 ! histone methylation GO:0016571 29 13 0,000 0,03278165 0,05712237 ! chromatin silencing GO:0006342 29 13 0,000 0,03278165 0,05708166 ! gland morphogenesis GO:0022612 31 13 0,000 0,03278165 0,057041 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,03278165 0,0570004 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,03278165 0,05695986 ! spleen development GO:0048536 24 13 0,000 0,03278165 0,05691938 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,03278165 0,05687895 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,03278165 0,05683858 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03278165 0,05679827 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,03278165 0,05675802 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,03278165 0,05671782 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,03278165 0,05667768 ! insulin secretion GO:0030073 24 13 0,000 0,03278165 0,0566376 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,03278165 0,05659757 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,03278165 0,0565576 ! acrosome reaction GO:0007340 19 13 0,000 0,03278165 0,05651769 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,03278165 0,05647783 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,03278165 0,05643803 ! rRNA transcription GO:0009303 28 14 0,000 0,03525883 0,06066009 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,03525883 0,0606174 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,03525883 0,06057477 ! water transport GO:0006833 21 14 0,000 0,03525883 0,0605322 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,03525883 0,0604897 ! non-recombinational repair GO:0000726 29 14 0,000 0,03525883 0,06044725 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,03525883 0,06040486 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,03525883 0,06036253 ! RNA polyadenylation GO:0043631 32 14 0,000 0,03525883 0,06032026 ! lipid localization GO:0010876 32 14 0,000 0,03525883 0,06027804 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,03525883 0,06023589 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,03525883 0,0601938 ! regulated secretory pathway GO:0045055 24 14 0,000 0,03525883 0,06015176 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,03525883 0,06010979 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,03525883 0,06006787 ! arginine metabolic process GO:0006525 21 14 0,000 0,03525883 0,06002601 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,03525883 0,05998421 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,03525883 0,05994247 ! regulation of heart rate GO:0002027 25 14 0,000 0,03525883 0,05990078 ! fear response GO:0042596 34 14 0,000 0,03525883 0,05985916 ! organic alcohol transport GO:0015850 29 14 0,000 0,03525883 0,05981759 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,03525883 0,05977608 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,03525883 0,05973462 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03525883 0,05969323 ! neutral amino acid transport GO:0015804 28 14 0,000 0,03525883 0,05965189 ! bone mineralization GO:0030282 18 14 0,000 0,03525883 0,05961061 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,03525883 0,05956938 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,03525883 0,05952821 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,03525883 0,0594871 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,03525883 0,05944605 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,03525883 0,05940505 ! regulation of cellular pH GO:0030641 27 14 0,000 0,03525883 0,05936411 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,03525883 0,05932323 ! ribosome assembly GO:0042255 18 14 0,000 0,03525883 0,0592824 ! cerebellum development GO:0021549 23 14 0,000 0,03525883 0,05924163 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,03525883 0,05920091 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,03525883 0,05916025 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,03525883 0,05911965 ! response to gamma radiation GO:0010332 30 14 0,000 0,03525883 0,0590791 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,03525883 0,05903861 ! NADP metabolic process GO:0006739 24 14 0,000 0,03525883 0,05899817 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,03525883 0,05895779 ! oxygen transport GO:0015671 22 14 0,000 0,03525883 0,05891746 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03525883 0,05887719 ! male genitalia development GO:0030539 26 14 0,000 0,03525883 0,05883697 ! regulation of axon extension GO:0030516 43 14 0,000 0,03525883 0,05879681 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,03525883 0,0587567 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,03525883 0,05871665 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,03525883 0,05867665 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03772974 0,06274592 ! lactation GO:0007595 30 15 0,000 0,03772974 0,06270324 ! reproductive cellular process GO:0048610 22 15 0,000 0,03772974 0,06266061 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03772974 0,06261804 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,03772974 0,06257553 ! superoxide anion generation GO:0042554 22 15 0,000 0,03772974 0,06253308 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,03772974 0,06249068 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,03772974 0,06244835 ! copper ion transport GO:0006825 22 15 0,000 0,03772974 0,06240607 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,03772974 0,06236384 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,03772974 0,06232168 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,03772974 0,06227957 ! sulfate transport GO:0008272 27 15 0,000 0,03772974 0,06223752 ! response to cAMP GO:0051591 25 15 0,000 0,03772974 0,06219552 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,03772974 0,06215358 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,03772974 0,0621117 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,03772974 0,06206987 ! response to hexose stimulus GO:0009746 25 15 0,000 0,03772974 0,0620281 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,03772974 0,06198639 ! vesicle coating GO:0006901 38 15 0,000 0,03772974 0,06194473 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,03772974 0,06190313 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,03772974 0,06186158 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,03772974 0,06182009 ! regulation of exocytosis GO:0017157 26 15 0,000 0,03772974 0,06177866 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,03772974 0,06173728 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,03772974 0,06169596 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,03772974 0,06165469 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,03772974 0,06161348 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,03772974 0,06157232 ! regulation of vasodilation GO:0042312 27 15 0,000 0,03772974 0,06153122 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,03772974 0,06149017 ! histone deacetylation GO:0016575 24 15 0,000 0,03772974 0,06144917 ! water homeostasis GO:0030104 28 15 0,000 0,03772974 0,06140823 ! cofactor transport GO:0051181 30 15 0,000 0,03772974 0,06136735 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03772974 0,06132652 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,03772974 0,06128574 ! intestinal absorption GO:0050892 31 15 0,000 0,03772974 0,06124502 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03772974 0,06120436 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,03772974 0,06116374 ! heme biosynthetic process GO:0006783 33 15 0,000 0,03772974 0,06112318 ! cell killing GO:0001906 32 15 0,000 0,03772974 0,06108268 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,03772974 0,06104223 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,03772974 0,06100183 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,03772974 0,06096148 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,03772974 0,06092119 ! actin filament polymerization GO:0030041 27 15 0,000 0,03772974 0,06088095 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,03772974 0,06084077 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,04019439 0,06477236 ! positive regulation of cell size GO:0045793 29 16 0,000 0,04019439 0,06472967 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,04019439 0,06468702 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,04019439 0,06464444 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,04019439 0,06460191 ! bone remodeling GO:0046849 28 16 0,000 0,04019439 0,06455944 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,04019439 0,06451702 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,04019439 0,06447466 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04019439 0,06443235 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,04019439 0,0643901 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,04019439 0,06434791 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,04019439 0,06430577 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,04019439 0,06426368 ! startle response GO:0001964 28 16 0,000 0,04019439 0,06422165 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,04019439 0,06417968 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,04019439 0,06413776 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,04019439 0,06409589 ! protein polyubiquitination GO:0000209 41 16 0,000 0,04019439 0,06405408 ! glutamate metabolic process GO:0006536 25 16 0,000 0,04019439 0,06401232 ! pituitary gland development GO:0021983 30 16 0,000 0,04019439 0,06397062 ! response to osmotic stress GO:0006970 27 16 0,000 0,04019439 0,06392897 ! lysosomal transport GO:0007041 31 16 0,000 0,04019439 0,06388738 ! fructose metabolic process GO:0006000 25 16 0,000 0,04019439 0,06384584 ! L-amino acid transport GO:0015807 33 16 0,000 0,04019439 0,06380436 ! stem cell development GO:0048864 46 16 0,000 0,04019439 0,06376292 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04019439 0,06372155 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04019439 0,06368022 ! intermediate filament-based process GO:0045103 36 16 0,000 0,04019439 0,06363895 ! negative regulation of immune response GO:0050777 38 16 0,000 0,04019439 0,06359774 ! axon cargo transport GO:0008088 46 16 0,000 0,04019439 0,06355657 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,04019439 0,06351546 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,04019439 0,0634744 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,04019439 0,0634334 ! DNA replication initiation GO:0006270 28 16 0,000 0,04019439 0,06339245 ! neuron recognition GO:0008038 40 16 0,000 0,04019439 0,06335155 ! mRNA splice site selection GO:0006376 44 16 0,000 0,04019439 0,0633107 ! tissue regeneration GO:0042246 27 16 0,000 0,04019439 0,06326991 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,04019439 0,06322917 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,04019439 0,06318848 ! biomineral formation GO:0031214 22 16 0,000 0,04019439 0,06314785 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,04019439 0,06310726 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,04019439 0,06306673 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,04019439 0,06302625 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04019439 0,06298583 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,04019439 0,06294545 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,04019439 0,06290513 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,04019439 0,06286485 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,04019439 0,06282463 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04019439 0,06278447 ! peptide hormone processing GO:0016486 27 16 0,000 0,04019439 0,06274435 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,0426528 0,06653946 ! metencephalon development GO:0022037 32 17 0,000 0,0426528 0,066497 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,0426528 0,06645459 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,0426528 0,06641223 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,0426528 0,06636993 ! signal complex assembly GO:0007172 47 17 0,000 0,0426528 0,06632769 ! filopodium assembly GO:0046847 42 17 0,000 0,0426528 0,06628549 ! endothelial cell migration GO:0043542 31 17 0,000 0,0426528 0,06624335 ! gene silencing by RNA GO:0031047 38 17 0,000 0,0426528 0,06620127 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,0426528 0,06615923 ! glial cell development GO:0021782 28 17 0,000 0,0426528 0,06611725 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,0426528 0,06607533 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,0426528 0,06603346 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,0426528 0,06599164 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,0426528 0,06594987 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,0426528 0,06590816 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,0426528 0,06586649 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,0426528 0,06582489 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,0426528 0,06578333 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,0426528 0,06574183 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,0426528 0,06570037 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,0426528 0,06565898 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,0426528 0,06561763 GO:0031114|regulation of microtubule depolymerization, ! membrane budding GO:0006900 42 17 0,000 0,0426528 0,06557633 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,0426528 0,06553509 ! regulation of protein binding GO:0043393 33 17 0,000 0,0426528 0,0654939 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,0426528 0,06545276 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,0426528 0,06541167 ! genitalia development GO:0048806 32 17 0,000 0,0426528 0,06537064 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,0426528 0,06532965 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,0426528 0,06528872 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,0426528 0,06524784 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,0426528 0,065207 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,0426528 0,06516622 ! steroid catabolic process GO:0006706 34 17 0,000 0,0426528 0,0651255 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,0426528 0,06508482 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,0426528 0,06504419 ! gas transport GO:0015669 26 17 0,000 0,0426528 0,06500361 ! organic cation transport GO:0015695 32 17 0,000 0,0426528 0,06496309 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,0426528 0,06492261 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,0426528 0,06488219 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,04510498 0,06856968 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,04510498 0,06852703 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,04510498 0,06848444 ! limbic system development GO:0021761 40 18 0,000 0,04510498 0,06844191 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04510498 0,06839942 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,04510498 0,06835699 ! adult walking behavior GO:0007628 36 18 0,000 0,04510498 0,06831461 ! patterning of blood vessels GO:0001569 43 18 0,000 0,04510498 0,06827229 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,04510498 0,06823001 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,04510498 0,06818779 ! centrosome cycle GO:0007098 26 18 0,000 0,04510498 0,06814562 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,04510498 0,0681035 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,04510498 0,06806144 ! glycine metabolic process GO:0006544 30 18 0,000 0,04510498 0,06801943 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04510498 0,06797746 ! response to retinoic acid GO:0032526 31 18 0,000 0,04510498 0,06793555 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,04510498 0,0678937 ! DNA integration GO:0015074 32 18 0,000 0,04510498 0,06785189 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,04510498 0,06781013 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,04510498 0,06776843 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,04510498 0,06772678 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,04510498 0,06768518 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,04510498 0,06764363 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,04510498 0,06760213 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,04510498 0,06756068 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,04510498 0,06751928 GO:0033014|tetrapyrrole biosynthetic process, ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,04510498 0,06747794 ! detection of bacterium GO:0016045 22 18 0,000 0,04510498 0,06743664 ! nerve development GO:0021675 34 18 0,000 0,04510498 0,06739539 ! defense response to virus GO:0051607 43 18 0,000 0,04510498 0,0673542 ! microspike assembly GO:0030035 46 18 0,000 0,04510498 0,06731305 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,04510498 0,06727196 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,04510498 0,06723091 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,04755095 0,07083352 ! positive regulation of translation GO:0045727 31 19 0,000 0,04755095 0,07079035 ! negative regulation of defense response GO:0031348 27 19 0,000 0,04755095 0,07074724 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,04755095 0,07070418 ! neuron maturation GO:0042551 46 19 0,000 0,04755095 0,07066117 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,04755095 0,07061822 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,04755095 0,07057531 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,04755095 0,07053246 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,04755095 0,07048966 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,04755095 0,07044692 ! inositol metabolic process GO:0006020 33 19 0,000 0,04755095 0,07040422 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04755095 0,07036158 ! memory GO:0007613 34 19 0,000 0,04755095 0,07031899 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,04755095 0,07027645 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,04755095 0,07023396 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,04755095 0,07019152 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,04755095 0,07014914 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,04755095 0,0701068 ! cerebral cortex development GO:0021987 40 19 0,000 0,04755095 0,07006452 ! pigmentation during development GO:0048066 42 19 0,000 0,04755095 0,07002228 ! response to vitamin A GO:0033189 32 19 0,000 0,04755095 0,0699801 ! heme metabolic process GO:0042168 40 19 0,000 0,04755095 0,06993797 ! neuromuscular junction development GO:0007528 43 19 0,000 0,04755095 0,06989589 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,04755095 0,06985386 ! response to fungus GO:0009620 26 19 0,000 0,04755095 0,06981188 ! protein export from nucleus GO:0006611 40 19 0,000 0,04755095 0,06976995 ! heart process GO:0003015 32 19 0,000 0,04755095 0,06972807 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,04755095 0,06968624 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,04755095 0,06964447 ! visual learning GO:0008542 38 19 0,000 0,04755095 0,06960274 ! cellular pigmentation GO:0033059 37 19 0,000 0,04755095 0,06956106 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,04755095 0,06951943 ! vitamin transport GO:0051180 31 19 0,000 0,04755095 0,06947785 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,04755095 0,06943632 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,04755095 0,06939484 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,04755095 0,06935341 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,04755095 0,06931203 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,04755095 0,0692707 ! cilium assembly GO:0042384 38 19 0,000 0,04755095 0,06922942 ! peptide hormone secretion GO:0030072 32 19 0,000 0,04755095 0,06918819 ! protein secretion GO:0009306 45 20 0,000 0,04999072 0,07269484 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,04999072 0,07265159 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,04999072 0,0726084 ! positive regulation of ossification GO:0045778 50 20 0,000 0,04999072 0,07256526 ! skin development GO:0043588 42 20 0,000 0,04999072 0,07252217 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,04999072 0,07247913 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,04999072 0,07243614 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,04999072 0,0723932 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,04999072 0,07235031 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,04999072 0,07230748 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,04999072 0,07226469 ! bile acid metabolic process GO:0008206 34 20 0,000 0,04999072 0,07222196 ! response to alkaloid GO:0043279 38 20 0,000 0,04999072 0,07217927 ! retinoid metabolic process GO:0001523 34 20 0,000 0,04999072 0,07213664 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,04999072 0,07209405 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,04999072 0,07205152 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,04999072 0,07200904 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,04999072 0,0719666 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,04999072 0,07192422 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,04999072 0,07188189 ! body fluid secretion GO:0007589 33 20 0,000 0,04999072 0,0718396 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,04999072 0,07179737 ! peptide secretion GO:0002790 38 20 0,000 0,04999072 0,07175519 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,04999072 0,07171305 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,04999072 0,07167097 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,04999072 0,07162893 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,04999072 0,07158695 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,04999072 0,07154501 ! cell-cell junction organization GO:0045216 43 20 0,000 0,04999072 0,07150312 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,04999072 0,07146128 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,04999072 0,07141949 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,04999072 0,07137775 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,04999072 0,07133606 ! regulation of glucose import GO:0046324 30 20 0,000 0,04999072 0,07129441 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,04999072 0,07125282 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,04999072 0,07121127 ! negative regulation of translation GO:0017148 32 20 0,000 0,04999072 0,07116977 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,04999072 0,07112832 ! regulation of cell killing GO:0031341 46 21 0,000 0,05242431 0,07454749 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,05242431 0,07450412 ! hormone secretion GO:0046879 39 21 0,000 0,05242431 0,07446081 ! lipid phosphorylation GO:0046834 43 21 0,000 0,05242431 0,07441754 ! cAMP metabolic process GO:0046058 41 21 0,000 0,05242431 0,07437433 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,05242431 0,07433116 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,05242431 0,07428804 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,05242431 0,07424498 ! ovarian follicle development GO:0001541 39 21 0,000 0,05242431 0,07420196 ! smooth muscle contraction GO:0006939 48 21 0,000 0,05242431 0,074159 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,05242431 0,07411608 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,05242431 0,07407321 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,05242431 0,0740304 ! plasma membrane fusion GO:0045026 33 21 0,000 0,05242431 0,07398763 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,05242431 0,07394491 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,05242431 0,07390224 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,05242431 0,07385962 ! sensory perception of pain GO:0019233 33 21 0,000 0,05242431 0,07381705 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,05242431 0,07377453 ! diencephalon development GO:0021536 36 21 0,000 0,05242431 0,07373206 ! collagen fibril organization GO:0030199 62 21 0,000 0,05242431 0,07368964 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,05242431 0,07364726 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,05242431 0,07360494 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,05242431 0,07356266 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,05242431 0,07352043 ! collagen catabolic process GO:0030574 29 21 0,000 0,05242431 0,07347825 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,05242431 0,07343612 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,05242431 0,07339403 ! sperm-egg recognition GO:0035036 23 21 0,000 0,05242431 0,073352 ! actin filament-based movement GO:0030048 47 21 0,000 0,05242431 0,07331001 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,05242431 0,07326807 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,05485173 0,0766168 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,05485173 0,07657302 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,05485173 0,07652929 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,05485173 0,07648561 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,05485173 0,07644198 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,05485173 0,0763984 ! microtubule-based transport GO:0010970 59 22 0,000 0,05485173 0,07635486 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,05485173 0,07631138 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,05485173 0,07626795 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,05485173 0,07622457 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,05485173 0,07618123 ! cellular response to starvation GO:0009267 37 22 0,000 0,05485173 0,07613795 ! vacuolar transport GO:0007034 41 22 0,000 0,05485173 0,07609471 ! central nervous system neuron development GO:0021954 47 22 0,000 0,05485173 0,07605152 ! fucose metabolic process GO:0006004 44 22 0,000 0,05485173 0,07600839 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,05485173 0,0759653 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,05485173 0,07592226 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,05485173 0,07587927 ! ureteric bud development GO:0001657 50 22 0,000 0,05485173 0,07583632 ! cell aging GO:0007569 48 22 0,000 0,05485173 0,07579343 ! stem cell differentiation GO:0048863 57 22 0,000 0,05485173 0,07575059 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,05485173 0,07570779 ! cytolysis GO:0019835 27 22 0,000 0,05485173 0,07566504 ! renal system process GO:0003014 42 22 0,000 0,05485173 0,07562234 ! vasodilation GO:0042311 40 22 0,000 0,05485173 0,07557969 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,05485173 0,07553708 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,05485173 0,07549453 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,05485173 0,07545202 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,05485173 0,07540956 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,05485173 0,07536715 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,05485173 0,07532478 ! sarcomere organization GO:0045214 32 22 0,000 0,05485173 0,07528246 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,05485173 0,07524019 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,05485173 0,07519797 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,05485173 0,0751558 ! gut development GO:0048565 44 22 0,000 0,05485173 0,07511367 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,05485173 0,07507159 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,05485173 0,07502956 ! protein stabilization GO:0050821 41 22 0,000 0,05485173 0,07498757 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,05727301 0,07825389 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,05727301 0,07821015 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,05727301 0,07816646 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,05727301 0,07812281 ! gluconeogenesis GO:0006094 38 23 0,000 0,05727301 0,07807922 ! glycerol metabolic process GO:0006071 40 23 0,000 0,05727301 0,07803567 ! viral genome replication GO:0019079 44 23 0,000 0,05727301 0,07799217 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,05727301 0,07794872 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,05727301 0,07790532 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,05727301 0,07786197 ! regeneration GO:0031099 42 23 0,000 0,05727301 0,07781866 ! axis specification GO:0009798 43 23 0,000 0,05727301 0,07777541 ! visual behavior GO:0007632 46 23 0,000 0,05727301 0,0777322 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,05727301 0,07768904 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,05727301 0,07764593 ! response to ethanol GO:0045471 47 23 0,000 0,05727301 0,07760286 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,05727301 0,07755984 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,05727301 0,07751687 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,05727301 0,07747395 ! peroxisome organization GO:0007031 43 23 0,000 0,05727301 0,07743108 ! lysosome organization GO:0007040 47 23 0,000 0,05727301 0,07738825 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,05727301 0,07734547 ! vesicle targeting GO:0006903 49 23 0,000 0,05727301 0,07730274 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,05727301 0,07726005 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,05727301 0,07721742 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,05727301 0,07717482 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,05727301 0,07713228 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,05727301 0,07708978 ! DNA modification GO:0006304 36 23 0,000 0,05727301 0,07704733 ! fatty acid transport GO:0015908 47 23 0,000 0,05727301 0,07700493 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,05727301 0,07696257 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,05727301 0,07692026 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,05727301 0,076878 ! hormone transport GO:0009914 41 23 0,000 0,05727301 0,07683578 ! cell-cell recognition GO:0009988 28 23 0,000 0,05727301 0,07679361 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,05727301 0,07675149 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,05727301 0,07670941 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,05727301 0,07666737 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,05968815 0,07985659 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,05968815 0,07981289 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,05968815 0,07976922 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,05968815 0,07972561 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,05968815 0,07968205 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,05968815 0,07963853 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,05968815 0,07959506 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,05968815 0,07955163 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,05968815 0,07950826 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,05968815 0,07946493 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,05968815 0,07942165 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,05968815 0,07937841 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,05968815 0,07933522 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,05968815 0,07929208 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,05968815 0,07924899 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,05968815 0,07920594 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,05968815 0,07916294 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,05968815 0,07911999 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,05968815 0,07907708 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,05968815 0,07903422 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,05968815 0,07899141 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,05968815 0,07894864 ! membrane depolarization GO:0051899 45 24 0,000 0,05968815 0,07890592 ! pallium development GO:0021543 56 24 0,000 0,05968815 0,07886325 ! oogenesis GO:0048477 44 24 0,000 0,05968815 0,07882062 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,05968815 0,07877803 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,05968815 0,0787355 ! platelet activation GO:0030168 41 24 0,000 0,05968815 0,07869301 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,05968815 0,07865056 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,05968815 0,07860816 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,05968815 0,07856581 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,05968815 0,0785235 ! regulation of amine transport GO:0051952 41 24 0,000 0,05968815 0,07848124 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,05968815 0,07843902 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,06209717 0,08156096 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,06209717 0,08151713 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,06209717 0,08147335 ! leukocyte adhesion GO:0007159 55 25 0,000 0,06209717 0,08142962 ! phototransduction GO:0007602 37 25 0,000 0,06209717 0,08138593 ! keratinization GO:0031424 37 25 0,000 0,06209717 0,08134229 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,06209717 0,0812987 ! vacuole organization GO:0007033 49 25 0,000 0,06209717 0,08125516 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,06209717 0,08121166 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,06209717 0,08116821 ! receptor metabolic process GO:0043112 53 25 0,000 0,06209717 0,0811248 ! chromosome condensation GO:0030261 48 25 0,000 0,06209717 0,08108144 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,06209717 0,08103813 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,06209717 0,08099486 ! interaction with host GO:0051701 66 25 0,000 0,06209717 0,08095164 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,06209717 0,08090847 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,06209717 0,08086534 ! immunoglobulin production GO:0002377 62 25 0,000 0,06209717 0,08082226 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,06209717 0,08077922 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,06209717 0,08073623 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,06209717 0,08069329 ! liver development GO:0001889 55 25 0,000 0,06209717 0,08065039 ! protein tetramerization GO:0051262 57 25 0,000 0,06209717 0,08060753 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,06450008 0,08368226 ! myelination GO:0042552 50 26 0,000 0,06450008 0,08363785 ! initiation of viral infection GO:0019059 60 26 0,000 0,06450008 0,08359347 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,06450008 0,08354915 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,06450008 0,08350488 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,06450008 0,08346065 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,06450008 0,08341646 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,06450008 0,08337233 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,06450008 0,08332824 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,06450008 0,0832842 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,06450008 0,0832402 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,06450008 0,08319625 ! digestive system process GO:0022600 49 26 0,000 0,06450008 0,08315235 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,06450008 0,08310849 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,06450008 0,08306468 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,06450008 0,08302092 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,06450008 0,0829772 ! negative regulation of cell development GO:0010721 83 26 0,000 0,06450008 0,08293353 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,06450008 0,0828899 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,06450008 0,08284632 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,06450008 0,08280279 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,06450008 0,0827593 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,06450008 0,08271585 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,06450008 0,08267246 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,06450008 0,0826291 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,06450008 0,0825858 ! blastocyst development GO:0001824 50 26 0,000 0,06450008 0,08254254 ! telomere organization GO:0032200 46 26 0,000 0,06450008 0,08249932 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 58 26 0,000 0,06450008 0,08245615 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,06450008 0,08241302 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,06450008 0,08236994 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,06450008 0,08232691 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,06689691 0,08534159 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,06689691 0,08529705 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,06689691 0,08525256 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,06689691 0,08520811 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,06689691 0,0851637 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,06689691 0,08511935 ! iron ion transport GO:0006826 65 27 0,000 0,06689691 0,08507504 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,06689691 0,08503077 ! superoxide metabolic process GO:0006801 41 27 0,000 0,06689691 0,08498656 ! tube lumen formation GO:0035148 59 27 0,000 0,06689691 0,08494238 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,06689691 0,08489826 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,06689691 0,08485418 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,06689691 0,08481014 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,06689691 0,08476616 ! response to starvation GO:0042594 47 27 0,000 0,06689691 0,08472221 ! response to toxin GO:0009636 49 27 0,000 0,06689691 0,08467832 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,06689691 0,08463446 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,06689691 0,08459066 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,06689691 0,08454689 ! leukocyte proliferation GO:0070661 59 27 0,000 0,06689691 0,08450318 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,06689691 0,08445951 ! neuron fate commitment GO:0048663 52 28 0,000 0,06928766 0,08743273 ! vesicle docking GO:0048278 55 28 0,000 0,06928766 0,08738759 ! circadian rhythm GO:0007623 56 28 0,000 0,06928766 0,0873425 ! dendrite development GO:0016358 67 28 0,000 0,06928766 0,08729745 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,06928766 0,08725245 ! fat cell differentiation GO:0045444 57 28 0,000 0,06928766 0,0872075 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,06928766 0,08716259 ! sperm motility GO:0030317 37 28 0,000 0,06928766 0,08711773 ! base-excision repair GO:0006284 41 28 0,000 0,06928766 0,08707292 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,06928766 0,08702815 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,06928766 0,08698343 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,06928766 0,08693876 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,06928766 0,08689413 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,06928766 0,08684954 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,06928766 0,086805 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,06928766 0,08676051 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,06928766 0,08671606 ! lipid oxidation GO:0034440 48 28 0,000 0,06928766 0,08667166 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,06928766 0,08662731 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,06928766 0,086583 ! translational initiation GO:0006413 66 29 0,000 0,07167236 0,08951716 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,07167236 0,08947142 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,07167236 0,08942572 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,07167236 0,08938008 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,07167236 0,08933447 ! primary neural tube formation GO:0014020 61 29 0,000 0,07167236 0,08928892 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,07167236 0,08924341 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,07167236 0,08919795 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,07167236 0,08915253 ! synaptogenesis GO:0007416 46 29 0,000 0,07167236 0,08910716 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,07167236 0,08906183 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,07167236 0,08901656 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,07167236 0,08897133 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,07167236 0,08892614 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,07405101 0,09183077 ! phenol metabolic process GO:0018958 56 30 0,000 0,07405101 0,09178418 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,07405101 0,09173763 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,07405101 0,09169114 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,07405101 0,09164469 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,07405101 0,09159829 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,07405101 0,09155193 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,07405101 0,09150562 ! acute-phase response GO:0006953 50 30 0,000 0,07405101 0,09145936 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,07405101 0,09141314 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,07405101 0,09136698 ! myofibril assembly GO:0030239 50 30 0,000 0,07405101 0,09132085 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,07405101 0,09127478 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,07405101 0,09122875 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,07405101 0,09118277 ! cell fate determination GO:0001709 64 30 0,000 0,07405101 0,09113683 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,07405101 0,09109094 ! phospholipid transport GO:0015914 65 30 0,000 0,07405101 0,0910451 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,07405101 0,0909993 ! neurotransmitter secretion GO:0007269 55 30 0,000 0,07405101 0,09095355 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,07405101 0,09090785 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,07405101 0,09086219 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,07405101 0,09081657 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,07642363 0,09367934 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,07642363 0,09363236 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,07642363 0,09358543 ! cell junction assembly GO:0034329 85 31 0,000 0,07642363 0,09353854 ! regulation of innate immune response GO:0045088 57 31 0,000 0,07642363 0,0934917 ! ovulation cycle process GO:0022602 55 31 0,000 0,07642363 0,09344491 ! peptide transport GO:0015833 60 31 0,000 0,07642363 0,09339817 ! male gonad development GO:0008584 56 31 0,000 0,07642363 0,09335147 ! detection of light stimulus GO:0009583 44 31 0,000 0,07642363 0,09330481 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,07642363 0,09325821 ! natural killer cell activation GO:0030101 50 31 0,000 0,07642363 0,09321165 ! ensheathment of neurons GO:0007272 64 31 0,000 0,07642363 0,09316514 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,07642363 0,09311867 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,07642363 0,09307225 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,07642363 0,09302588 ! eye morphogenesis GO:0048592 65 31 0,000 0,07642363 0,09297955 ! response to heat GO:0009408 54 31 0,000 0,07642363 0,09293327 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,07642363 0,09288703 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,07879024 0,09571584 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,07879024 0,09566827 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,07879024 0,09562075 ! spindle organization GO:0007051 50 32 0,000 0,07879024 0,09557327 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,07879024 0,09552584 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,07879024 0,09547845 ! metanephros development GO:0001656 81 32 0,000 0,07879024 0,09543112 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,07879024 0,09538383 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,07879024 0,09533658 ! muscle cell development GO:0055001 52 32 0,000 0,07879024 0,09528939 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,07879024 0,09524224 ! ovulation cycle GO:0042698 57 32 0,000 0,07879024 0,09519514 ! peripheral nervous system development GO:0007422 68 32 0,000 0,07879024 0,09514808 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,07879024 0,09510107 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,07879024 0,09505411 ! gene silencing GO:0016458 71 32 0,000 0,07879024 0,09500719 ! regulation of pH GO:0006885 56 33 0,000 0,08115086 0,0978054 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,08115086 0,09775717 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,08115086 0,09770899 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,08115086 0,09766086 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,08115086 0,09761277 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,08115086 0,09756473 ! response to ionizing radiation GO:0010212 74 33 0,000 0,08115086 0,09751674 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,08115086 0,0974688 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,08115086 0,0974209 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,08115086 0,09737306 GO:0060326|cell chemotaxis, ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,08115086 0,09732525 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,08115086 0,0972775 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,08115086 0,09722979 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,08350549 0,10000191 ! glial cell differentiation GO:0010001 67 34 0,000 0,08350549 0,09995292 ! post-embryonic development GO:0009791 76 34 0,000 0,08350549 0,09990397 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,08350549 0,09985507 ! cholesterol transport GO:0030301 62 34 0,000 0,08350549 0,09980621 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,08350549 0,09975741 ! spliceosome assembly GO:0000245 75 34 0,000 0,08350549 0,09970865 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,08350549 0,09965994 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,08350549 0,09961128 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,08350549 0,09956267 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,08350549 0,0995141 ! adult locomotory behavior GO:0008344 62 34 0,000 0,08350549 0,09946558 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,08350549 0,09941711 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,08585415 0,10216351 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,08585415 0,10211377 ! negative regulation of secretion GO:0051048 68 35 0,000 0,08585415 0,10206408 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,08585415 0,10201444 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,08585415 0,10196484 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,08585415 0,1019153 ! membrane docking GO:0022406 69 35 0,000 0,08585415 0,1018658 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,08585415 0,10181635 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,08585415 0,10176695 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,08585415 0,1017176 ! ceramide metabolic process GO:0006672 72 35 0,000 0,08585415 0,10166829 ! telencephalon development GO:0021537 81 35 0,000 0,08585415 0,10161903 ! sterol transport GO:0015918 63 35 0,000 0,08585415 0,10156982 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,08585415 0,10152066 ! vesicle localization GO:0051648 70 35 0,000 0,08585415 0,10147155 ! regulation of muscle development GO:0048634 82 36 0,000 0,08819686 0,10419 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,08819686 0,10413964 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,08819686 0,10408934 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,08819686 0,10403907 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,08819686 0,10398886 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,08819686 0,1039387 ! positive regulation of cell development GO:0010720 85 36 0,000 0,08819686 0,10388858 ! protein targeting to membrane GO:0006612 75 36 0,000 0,08819686 0,10383852 ! regulation of proteolysis GO:0030162 77 36 0,000 0,08819686 0,1037885 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,08819686 0,10373853 ! aerobic respiration GO:0009060 56 36 0,000 0,08819686 0,10368861 ! cytokine production GO:0001816 68 36 0,000 0,08819686 0,10363873 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,08819686 0,10358891 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,09053363 0,10628239 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,09053363 0,10623134 ! sister chromatid segregation GO:0000819 65 37 0,000 0,09053363 0,10618034 ! odontogenesis GO:0042476 74 37 0,000 0,09053363 0,10612939 ! actomyosin structure organization GO:0031032 68 37 0,000 0,09053363 0,10607849 ! cell junction organization GO:0034330 96 37 0,000 0,09053363 0,10602764 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,09053363 0,10597684 ! female gonad development GO:0008585 71 37 0,000 0,09053363 0,10592608 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,09053363 0,10587537 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,09053363 0,10582472 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,09053363 0,10577411 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,09286448 0,10844547 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,09286448 0,10839366 ! meiosis I GO:0007127 74 38 0,000 0,09286448 0,10834189 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,09286448 0,10829018 ! organic anion transport GO:0015711 82 38 0,000 0,09286448 0,10823851 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,09286448 0,1081869 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,09286448 0,10813533 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,09286448 0,10808381 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,09286448 0,10803234 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,09286448 0,10798092 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,09286448 0,10792955 ! regulation of protein stability GO:0031647 77 38 0,000 0,09286448 0,10787823 ! pigment metabolic process GO:0042440 87 38 0,000 0,09286448 0,10782696 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,09286448 0,10777573 ! neural tube formation GO:0001841 79 38 0,000 0,09286448 0,10772456 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,09518942 0,11036913 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,09518942 0,11031677 ! negative regulation of binding GO:0051100 71 39 0,000 0,09518942 0,11026446 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,09518942 0,1102122 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,09518942 0,11016 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,09518942 0,11010784 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,09518942 0,11005573 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,09518942 0,11000367 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,09750847 0,11263035 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,09750847 0,11257712 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,09750847 0,11252394 ! learning GO:0007612 82 40 0,000 0,09750847 0,11247081 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,09750847 0,11241774 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,09750847 0,11236471 ! lipid homeostasis GO:0055088 75 40 0,000 0,09750847 0,11231173 ! mismatch repair GO:0006298 58 40 0,000 0,09750847 0,1122588 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,09750847 0,11220593 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,09750847 0,1121531 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,09750847 0,11210032 ! RNA export from nucleus GO:0006405 61 41 0,000 0,09982163 0,11470567 ! mRNA catabolic process GO:0006402 79 41 0,000 0,09982163 0,11465174 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,09982163 0,11459786 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,09982163 0,11454404 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,09982163 0,11449026 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,09982163 0,11443653 ! gliogenesis GO:0042063 91 41 0,000 0,09982163 0,11438286 ! feeding behavior GO:0007631 69 41 0,000 0,09982163 0,11432923 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,09982163 0,11427566 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,09982163 0,11422213 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,09982163 0,11416866 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,09982163 0,11411523 ! RNA modification GO:0009451 64 41 0,000 0,09982163 0,11406186 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,10212894 0,11664376 ! ear morphogenesis GO:0042471 64 42 0,000 0,10212894 0,11658925 ! organic ether metabolic process GO:0018904 59 42 0,000 0,10212894 0,1165348 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,10212894 0,11648039 ! T cell differentiation GO:0030217 93 42 0,000 0,10212894 0,11642604 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,10212894 0,11637173 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,10212894 0,11631748 ! regulation of protein secretion GO:0050708 77 42 0,000 0,10212894 0,11626328 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,10212894 0,11620913 ! cytokinesis GO:0000910 84 42 0,000 0,10212894 0,11615503 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,10443039 0,11871729 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,10443039 0,11866207 ! regulation of tube size GO:0035150 76 43 0,000 0,10443039 0,1186069 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,10443039 0,11855179 ! glucose transport GO:0015758 66 43 0,000 0,10443039 0,11849673 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,10443039 0,11844171 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,10443039 0,11838675 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,10443039 0,11833184 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,10443039 0,11827698 ! ion transmembrane transport GO:0034220 79 43 0,000 0,10443039 0,11822217 ! neuron migration GO:0001764 85 43 0,000 0,10443039 0,11816742 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,10672601 0,1207091 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,10672601 0,12065324 ! hexose transport GO:0008645 68 44 0,000 0,10672601 0,12059743 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 85 44 0,000 0,10672601 0,12054168 ! phagocytosis GO:0006909 105 44 0,000 0,10672601 0,12048598 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,10672601 0,12043032 ! double-strand break repair GO:0006302 85 44 0,000 0,10672601 0,12037472 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,10901582 0,12290062 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,10901582 0,12284393 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,10901582 0,12278729 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,10901582 0,12273071 ! B cell differentiation GO:0030183 124 45 0,000 0,10901582 0,12267418 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,10901582 0,1226177 ! female gamete generation GO:0007292 71 45 0,000 0,10901582 0,12256127 ! polyol metabolic process GO:0019751 77 45 0,000 0,10901582 0,12250489 ! developmental growth GO:0048589 88 45 0,000 0,10901582 0,12244857 ! maintenance of location in cell GO:0051651 101 45 0,000 0,10901582 0,1223923 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,11129981 0,12489914 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,11129981 0,1248418 ! glycolysis GO:0006096 71 46 0,000 0,11129981 0,12478451 ! leukocyte migration GO:0050900 75 46 0,000 0,11129981 0,12472727 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,11129981 0,12467008 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,11129981 0,12461294 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,11129981 0,12455586 ! pigmentation GO:0043473 103 46 0,000 0,11129981 0,12449883 ! neural tube development GO:0021915 91 47 0,000 0,11357802 0,12698906 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,11357802 0,12693097 ! response to insulin stimulus GO:0032868 98 47 0,000 0,11357802 0,12687293 ! positive regulation of defense response GO:0031349 88 48 0,000 0,11585044 0,12935221 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,11585044 0,12929312 ! mitochondrial transport GO:0006839 94 48 0,000 0,11585044 0,12923408 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,11585044 0,1291751 ! cellular component disassembly GO:0022411 89 48 0,000 0,11585044 0,12911617 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,11585044 0,12905729 ! endosome transport GO:0016197 127 48 0,000 0,11585044 0,12899847 ! male sex differentiation GO:0046661 93 48 0,000 0,11585044 0,1289397 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,11585044 0,12888098 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,11585044 0,12882232 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,11585044 0,12876371 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,11585044 0,12870516 ! methylation GO:0032259 97 48 0,000 0,11585044 0,12864665 ! response to calcium ion GO:0051592 94 49 0,000 0,11811711 0,13110409 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,11811711 0,13104455 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,11811711 0,13098507 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,11811711 0,13092564 ! JNK cascade GO:0007254 106 49 0,000 0,11811711 0,13086626 ! protein homooligomerization GO:0051260 84 49 0,000 0,11811711 0,13080694 ! regulation of action potential GO:0001508 102 50 0,000 0,12037803 0,13325035 ! regulation of ion transport GO:0043269 86 50 0,000 0,12037803 0,13319 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,12037803 0,13312971 ! endocrine system development GO:0035270 109 50 0,000 0,12037803 0,13306947 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,12037803 0,13300929 ! activation of caspase activity GO:0006919 95 50 0,000 0,12037803 0,13294915 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,12037803 0,13288908 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,12037803 0,13282906 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,12037803 0,13276909 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,12263322 0,13519538 ! viral infectious cycle GO:0019058 104 51 0,000 0,12263322 0,13513439 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,12263322 0,13507347 ! response to temperature stimulus GO:0009266 84 51 0,000 0,12263322 0,1350126 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,12263322 0,13495178 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,12263322 0,13489102 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,12488269 0,13730351 ! Notch signaling pathway GO:0007219 111 52 0,000 0,12488269 0,13724175 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,12488269 0,13718004 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,12488269 0,13711838 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,12488269 0,13705678 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,12488269 0,13699524 ! excretion GO:0007588 87 52 0,000 0,12488269 0,13693375 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,12488269 0,13687232 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,12488269 0,13681094 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,12488269 0,13674962 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,12488269 0,13668835 ! respiratory electron transport chain GO:0022904 83 53 0,000 0,12712645 0,13908192 ! positive regulation of growth GO:0045927 96 53 0,000 0,12712645 0,13901966 ! inner ear development GO:0048839 89 53 0,000 0,12712645 0,13895746 ! chromatin remodeling GO:0006338 122 53 0,000 0,12712645 0,13889531 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,12712645 0,13883322 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,12712645 0,13877119 ! vesicle organization GO:0016050 127 53 0,000 0,12712645 0,13870921 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,12712645 0,13864728 ! synapse organization GO:0050808 102 53 0,000 0,12712645 0,13858542 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,12936452 0,14096233 ! neuromuscular process GO:0050905 107 54 0,000 0,12936452 0,14089948 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,12936452 0,14083669 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,12936452 0,14077396 ! membrane fusion GO:0006944 122 54 0,000 0,12936452 0,14071128 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,12936452 0,14064866 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,12936452 0,14058609 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,12936452 0,14052358 ! RNA catabolic process GO:0006401 103 55 0,000 0,13159692 0,14288501 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,13159692 0,14282154 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,13159692 0,14275812 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,13159692 0,14269476 ! cell maturation GO:0048469 107 55 0,000 0,13159692 0,14263145 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,13159692 0,1425682 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,13159692 0,142505 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,13382366 0,14485211 ! glucose catabolic process GO:0006007 88 56 0,000 0,13382366 0,14478796 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,13382366 0,14472386 ! regulation of DNA replication GO:0006275 105 56 0,000 0,13382366 0,14465982 ! RNA elongation GO:0006354 90 56 0,000 0,13382366 0,14459584 ! chloride transport GO:0006821 102 57 0,000 0,13604475 0,14693074 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,13604475 0,14686581 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 91 57 0,000 0,13604475 0,14680094 ! regulation of actin filament length GO:0030832 118 58 0,000 0,13826021 0,14912569 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,13826021 0,14905988 ! aging GO:0007568 112 58 0,000 0,13826021 0,14899413 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,13826021 0,14892843 ! maintenance of location GO:0051235 124 58 0,000 0,13826021 0,1488628 ! nuclear export GO:0051168 110 59 0,000 0,14047005 0,15117547 ! establishment of organelle localization GO:0051656 122 59 0,000 0,14047005 0,1511089 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,14267428 0,15341253 ! lipid modification GO:0030258 112 60 0,000 0,14267428 0,15334504 ! DNA catabolic process GO:0006308 94 60 0,000 0,14267428 0,1532776 ! regulation of endocytosis GO:0030100 104 60 0,000 0,14267428 0,15321023 ! adult behavior GO:0030534 104 60 0,000 0,14267428 0,15314291 ! kidney development GO:0001822 133 60 0,000 0,14267428 0,15307565 ! positive regulation of secretion GO:0051047 110 61 0,000 0,14487292 0,15536635 ! regulation of cellular component size GO:0032535 125 61 0,000 0,14487292 0,15529818 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,14487292 0,15523007 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,14487292 0,15516201 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,14487292 0,15509402 ! regulation of heart contraction GO:0008016 123 61 0,000 0,14487292 0,15502608 ! camera-type eye development GO:0043010 126 61 0,000 0,14487292 0,15495821 ! proton transport GO:0015992 117 61 0,000 0,14487292 0,15489039 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,14487292 0,15482264 ! viral reproductive process GO:0022415 132 62 0,000 0,14706599 0,1570976 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,14706599 0,15702894 ! tRNA processing GO:0008033 102 62 0,000 0,14706599 0,15696034 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,14925349 0,15922545 ! regulation of mitosis GO:0007088 112 63 0,000 0,14925349 0,15915595 GO:0051783|regulation of nuclear division, ! hydrogen transport GO:0006818 121 64 0,000 0,15143545 0,16141221 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,15143545 0,16134182 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,15143545 0,16127149 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,15361187 0,16351799 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,15361187 0,16344677 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,15361187 0,16337562 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,15361187 0,16330452 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,15361187 0,16323349 ! ear development GO:0043583 114 66 0,000 0,15578277 0,16546839 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,15578277 0,16539648 ! gonad development GO:0008406 115 66 0,000 0,15578277 0,16532463 ! activation of MAPK activity GO:0000187 124 67 0,000 0,15794816 0,16754987 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,15794816 0,16747715 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,15794816 0,16740449 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,15794816 0,16733189 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,15794816 0,16725936 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,16010806 0,16947313 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,16010806 0,16939973 ! hexose catabolic process GO:0019320 113 68 0,000 0,16010806 0,1693264 ! extracellular matrix organization GO:0030198 146 68 0,000 0,16010806 0,16925313 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,16010806 0,16917992 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,16010806 0,16910678 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,16010806 0,1690337 ! viral reproduction GO:0016032 142 68 0,000 0,16010806 0,16896068 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,16010806 0,16888773 ! cell projection assembly GO:0030031 138 68 0,000 0,16010806 0,16881484 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,16226247 0,17101261 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,16226247 0,17093886 ! urogenital system development GO:0001655 149 69 0,000 0,16226247 0,17086518 ! developmental maturation GO:0021700 128 69 0,000 0,16226247 0,17079157 ! single fertilization GO:0007338 83 69 0,000 0,16226247 0,17071801 ! cell redox homeostasis GO:0045454 114 70 0,000 0,16441143 0,17290448 ! activation of immune response GO:0002253 120 70 0,000 0,16441143 0,17283008 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,16441143 0,17275575 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,16655493 0,1749328 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,16655493 0,17485762 ! appendage morphogenesis GO:0035107 150 72 0,000 0,16869299 0,17702619 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,16869299 0,17695018 ! actin filament organization GO:0007015 167 72 0,000 0,16869299 0,17687424 ! B cell activation GO:0042113 179 72 0,000 0,16869299 0,17679836 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,16869299 0,17672255 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,16869299 0,1766468 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,16869299 0,17657111 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,16869299 0,17649549 ! appendage development GO:0048736 151 73 0,000 0,17082563 0,17865026 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,17082563 0,17857382 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,17082563 0,17849744 ! regulation of immune effector process GO:0002697 156 73 0,000 0,17082563 0,17842113 ! acute inflammatory response GO:0002526 118 74 0,000 0,17295286 0,18056574 ! amino acid transport GO:0006865 148 74 0,000 0,17295286 0,18048861 ! regulation of caspase activity GO:0043281 136 74 0,000 0,17295286 0,18041154 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,17295286 0,18033454 ! organelle localization GO:0051640 155 74 0,000 0,17295286 0,18025761 ! transition metal ion transport GO:0000041 143 75 0,000 0,17507469 0,18239124 ! reproductive structure development GO:0048608 131 75 0,000 0,17507469 0,18231349 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,17507469 0,18223581 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,17507469 0,1821582 ! eye development GO:0001654 155 75 0,000 0,17507469 0,18208065 ! axon guidance GO:0007411 162 75 0,000 0,17507469 0,18200317 ! rhythmic process GO:0048511 142 75 0,000 0,17507469 0,18192576 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,17719113 0,18404674 ! learning or memory GO:0007611 161 76 0,000 0,17719113 0,18396852 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,17719113 0,18389037 ! regulation of blood pressure GO:0008217 134 76 0,000 0,17719113 0,18381229 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,17719113 0,18373427 ! neurotransmitter transport GO:0006836 142 77 0,000 0,17930221 0,18584442 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,17930221 0,1857656 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,17930221 0,18568685 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,17930221 0,18560817 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,17930221 0,18552956 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,17930221 0,18545101 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,17930221 0,18537253 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,18140792 0,1874702 ! antigen processing and presentation GO:0019882 117 78 0,000 0,18140792 0,18739093 ! fertilization GO:0009566 99 78 0,000 0,18140792 0,18731173 ! blood coagulation GO:0007596 151 79 0,000 0,1835083 0,18940041 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,1835083 0,18932043 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,1835083 0,18924051 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,1835083 0,18916066 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,1835083 0,18908088 ! protein oligomerization GO:0051259 149 79 0,000 0,1835083 0,18900117 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,1835083 0,18892152 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,18560334 0,19099788 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,18560334 0,19091746 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,18560334 0,19083711 ! meiosis GO:0007126 143 81 0,000 0,18769307 0,19290457 GO:0051327|M phase of meiotic cell cycle, ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,18769307 0,19282345 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,18977749 0,1948829 ! meiotic cell cycle GO:0051321 144 82 0,000 0,18977749 0,19480102 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,19185663 0,19685248 ! exocytosis GO:0006887 153 83 0,000 0,19185663 0,19676983 ! response to drug GO:0042493 149 83 0,000 0,19185663 0,19668726 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,19185663 0,19660476 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,19185663 0,19652232 ! inorganic anion transport GO:0015698 156 83 0,000 0,19185663 0,19643996 ! response to metal ion GO:0010038 158 84 0,000 0,19393049 0,19848017 ! T cell activation GO:0042110 189 84 0,000 0,19393049 0,19839706 ! digestion GO:0007586 130 84 0,000 0,19393049 0,19831401 ! regulation of ligase activity GO:0051340 147 84 0,000 0,19393049 0,19823104 ! hemostasis GO:0007599 165 85 0,000 0,19599908 0,20026171 ! negative regulation of transport GO:0051051 164 85 0,000 0,19599908 0,20017799 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,19599908 0,20009434 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,19599908 0,20001076 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,19599908 0,19992724 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,19599908 0,1998438 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,19806242 0,20186337 ! regulation of lyase activity GO:0051339 169 86 0,000 0,19806242 0,20177919 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,20012053 0,20379093 ! mitochondrion organization GO:0007005 159 87 0,000 0,20012053 0,20370602 ! alcohol catabolic process GO:0046164 142 87 0,000 0,20012053 0,20362118 ! nucleosome assembly GO:0006334 126 87 0,000 0,20012053 0,20353641 ! cellular respiration GO:0045333 143 88 0,000 0,20217341 0,20553876 ! amine biosynthetic process GO:0009309 146 88 0,000 0,20217341 0,20545326 ! sensory perception of smell GO:0007608 117 88 0,000 0,20217341 0,20536783 ! chromatin assembly GO:0031497 128 88 0,000 0,20217341 0,20528248 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,20217341 0,20519719 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,20422108 0,20718941 ! tube morphogenesis GO:0035239 194 89 0,000 0,20422108 0,2071034 ! cellular defense response GO:0006968 123 89 0,000 0,20422108 0,20701747 ! regulation of neurological system process GO:0031644 175 89 0,000 0,20422108 0,20693161 ! response to inorganic substance GO:0010035 173 90 0,000 0,20626355 0,20891454 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,20626355 0,20882796 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,20626355 0,20874145 ! response to unfolded protein GO:0006986 139 90 0,000 0,20626355 0,20865502 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,20626355 0,20856865 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,20830084 0,21054156 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! gland development GO:0048732 220 91 0,000 0,20830084 0,21045449 ! defense response to bacterium GO:0042742 112 91 0,000 0,20830084 0,21036749 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,21033296 0,21233199 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,21033296 0,21224429 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,21235992 0,21420119 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,21235992 0,21411278 ! female pregnancy GO:0007565 166 94 0,000 0,21438173 0,21606211 ! sterol metabolic process GO:0016125 166 94 0,000 0,21438173 0,21597301 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,21438173 0,21588399 ! regulation of membrane potential GO:0042391 179 94 0,000 0,21438173 0,21579504 ! regulation of defense response GO:0031347 171 95 0,000 0,21639841 0,2177353 ! nucleosome organization GO:0034728 143 95 0,000 0,21639841 0,21764566 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,21639841 0,21755609 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,21639841 0,2174666 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,21639841 0,21737718 ! sex differentiation GO:0007548 171 96 0,000 0,21840997 0,21930766 ! response to protein stimulus GO:0051789 158 96 0,000 0,21840997 0,21921756 ! regulation of T cell activation GO:0050863 175 96 0,000 0,21840997 0,21912753 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,22041642 0,2210498 ! transcription initiation GO:0006352 171 97 0,000 0,22041642 0,22095909 ! leukocyte differentiation GO:0002521 232 98 0,000 0,22241777 0,22287392 ! forebrain development GO:0030900 210 98 0,000 0,22241777 0,22278254 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,22241777 0,22269124 ! mRNA transport GO:0051028 185 100 0,000 0,22640526 0,22659076 ! positive regulation of immune response GO:0050778 175 100 0,000 0,22640526 0,22649797 ! hormone metabolic process GO:0042445 171 100 0,000 0,22640526 0,22640526