pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/941-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of lipid kinase activity GO:0043550 12 7 3,000 2,038E-07 4,687E-04 ! actin filament-based movement GO:0030048 34 20 4,000 7,151E-07 8,224E-04 ! myeloid cell differentiation GO:0030099 85 59 6,000 8,716E-07 6,682E-04 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 3,000 1,198E-06 6,886E-04 GO:0007520|myoblast fusion, ! filopodium assembly GO:0046847 19 11 3,000 1,869E-06 8,598E-04 ! syncytium formation GO:0006949 15 11 3,000 1,869E-06 7,165E-04 ! ribosomal large subunit biogenesis GO:0042273 12 12 3,000 2,784E-06 9,148E-04 ! microspike assembly GO:0030035 23 12 3,000 2,784E-06 8,005E-04 ! myotube differentiation GO:0014902 21 14 3,000 5,553E-06 1,419E-03 ! nuclear migration GO:0007097 10 5 2,000 6,748E-06 1,552E-03 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 2,000 6,748E-06 1,411E-03 ! positive regulation of pseudopodium assembly GO:0031274 13 5 2,000 6,748E-06 1,293E-03 GO:0031272|regulation of pseudopodium assembly, ! endothelial cell migration GO:0043542 22 16 3,000 9,957E-06 1,762E-03 ! establishment or maintenance of cell polarity GO:0007163 61 34 4,000 1,161E-05 1,908E-03 ! macrophage differentiation GO:0030225 10 6 2,000 1,341E-05 2,056E-03 ! regulation of epidermal cell differentiation GO:0045604 7 6 2,000 1,341E-05 1,927E-03 ! leukocyte differentiation GO:0002521 143 90 6,000 1,517E-05 2,053E-03 ! plasma membrane fusion GO:0045026 23 19 3,000 2,077E-05 2,654E-03 ! establishment of nucleus localization GO:0040023 13 7 2,000 2,331E-05 2,822E-03 ! positive regulation of epidermis development GO:0045684 11 7 2,000 2,331E-05 2,681E-03 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 4,000 2,631E-05 2,881E-03 ! myeloid leukocyte differentiation GO:0002573 33 21 3,000 3,163E-05 3,307E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 2,000 3,705E-05 3,705E-03 ! UTP metabolic process GO:0046051 8 8 2,000 3,705E-05 3,551E-03 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! regulation of T cell differentiation in the thymus GO:0033081 12 8 2,000 3,705E-05 3,409E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 4,000 3,767E-05 3,332E-03 ! CTP metabolic process GO:0046036 9 9 2,000 5,522E-05 4,704E-03 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 9 9 2,000 5,522E-05 4,536E-03 ! nucleus localization GO:0051647 15 9 2,000 5,522E-05 4,379E-03 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 3,000 6,504E-05 4,986E-03 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of B cell proliferation GO:0030888 15 10 2,000 7,837E-05 5,815E-03 ! regulation of cell projection assembly GO:0060491 20 10 2,000 7,837E-05 5,633E-03 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 2,000 7,837E-05 5,462E-03 ! detection of bacterium GO:0016045 10 10 2,000 7,837E-05 5,302E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 4,000 8,683E-05 5,706E-03 ! establishment of organelle localization GO:0051656 85 52 4,000 9,539E-05 6,094E-03 ! negative regulation of protein complex assembly GO:0031333 42 28 3,000 1,031E-04 6,41E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 5,000 1,156E-04 6,994E-03 ! interphase GO:0051325 159 88 5,000 1,313E-04 7,742E-03 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 2,000 1,418E-04 8,155E-03 ! regulation of epidermis development GO:0045682 17 12 2,000 1,418E-04 7,956E-03 ! negative regulation of protein kinase activity GO:0006469 99 57 4,000 1,483E-04 8,121E-03 ! negative regulation of kinase activity GO:0033673 100 58 4,000 1,611E-04 8,619E-03 ! steroid hormone receptor signaling pathway GO:0030518 96 58 4,000 1,611E-04 8,423E-03 ! cytokinesis GO:0000910 52 33 3,000 1,991E-04 0,01017597 ! meiosis GO:0007126 96 61 4,000 2,048E-04 0,01023992 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of transferase activity GO:0051348 105 61 4,000 2,048E-04 0,01002205 ! meiotic cell cycle GO:0051321 97 62 4,000 2,212E-04 0,01059844 ! organelle localization GO:0051640 96 62 4,000 2,212E-04 0,01038214 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 2,000 2,316E-04 0,01065384 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 4,000 2,386E-04 0,01075816 ! negative regulation of cell cycle process GO:0010948 24 15 2,000 2,876E-04 0,01272195 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 2,000 2,876E-04 0,01248191 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 2,000 3,517E-04 0,01497999 ! G1 phase GO:0051318 27 16 2,000 3,517E-04 0,01470763 ! detection of biotic stimulus GO:0009595 19 16 2,000 3,517E-04 0,01444499 ! muscle cell differentiation GO:0042692 104 71 4,000 4,175E-04 0,0168452 ! positive regulation of DNA binding GO:0043388 57 41 3,000 4,663E-04 0,01849294 ! estrogen receptor signaling pathway GO:0030520 30 18 2,000 5,059E-04 0,01971979 ! regulation of cell shape GO:0008360 78 42 3,000 5,119E-04 0,01962296 ! positive regulation of binding GO:0051099 59 43 3,000 5,605E-04 0,02113521 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 5,968E-04 0,02213969 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 2,000 5,968E-04 0,02178827 ! regulation of DNA binding GO:0051101 119 77 4,000 6,071E-04 0,02181801 ! regulation of cell cycle process GO:0010564 122 81 4,000 7,653E-04 0,02707919 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 7,675E-04 0,02674603 ! negative regulation of T cell mediated immunity GO:0002710 11 5 1,000 7,675E-04 0,02634683 GO:0002707|negative regulation of lymphocyte mediated immunity, ! NAD biosynthetic process GO:0009435 7 5 1,000 7,675E-04 0,02595938 ! benzene and derivative metabolic process GO:0042537 11 5 1,000 7,675E-04 0,02558316 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 1,000 7,675E-04 0,02521768 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 1,000 7,675E-04 0,02486251 GO:0043088|regulation of Cdc42 GTPase activity, ! monocyte differentiation GO:0030224 8 5 1,000 7,675E-04 0,02451719 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 1,000 7,675E-04 0,02418134 ! negative regulation of immune system process GO:0002683 73 47 3,000 7,882E-04 0,02449849 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 2,000 8,086E-04 0,02479611 ! dicarboxylic acid metabolic process GO:0043648 33 22 2,000 9,302E-04 0,02815004 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 2,000 9,302E-04 0,02778446 ! rRNA metabolic process GO:0016072 107 85 4,000 9,524E-04 0,02808266 GO:0006364|rRNA processing, ! skeletal muscle fiber development GO:0048741 73 50 3,000 9,97E-04 0,02902639 ! membrane fusion GO:0006944 80 50 3,000 9,97E-04 0,02866356 ! skeletal muscle tissue development GO:0007519 123 87 4,000 1,058E-03 0,03003434 GO:0060538|skeletal muscle organ development, ! negative regulation of phosphorylation GO:0042326 41 23 2,000 1,063E-03 0,02980962 ! muscle fiber development GO:0048747 74 51 3,000 1,074E-03 0,02977402 ! cytokinesis during cell cycle GO:0033205 9 6 1,000 1,145E-03 0,03133855 ! male meiosis GO:0007140 7 6 1,000 1,145E-03 0,03096986 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 1,145E-03 0,03060974 ! response to interferon-gamma GO:0034341 12 6 1,000 1,145E-03 0,03025791 ! glutamate catabolic process GO:0006538 10 6 1,000 1,145E-03 0,02991407 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 1,000 1,145E-03 0,02957796 ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 1,145E-03 0,02924931 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 1,000 1,145E-03 0,02892789 ! aspartate family amino acid catabolic process GO:0009068 7 6 1,000 1,145E-03 0,02861346 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 1,000 1,145E-03 0,02830579 ! negative regulation of B cell activation GO:0050869 9 6 1,000 1,145E-03 0,02800466 ! positive regulation of cell projection organization GO:0031346 39 24 2,000 1,207E-03 0,02921592 ! cell projection assembly GO:0030031 76 53 3,000 1,242E-03 0,0297533 ! regulation of protein complex assembly GO:0043254 81 54 3,000 1,332E-03 0,03158523 ! DNA catabolic process GO:0006308 67 54 3,000 1,332E-03 0,03126293 ! regulation of chromosome organization GO:0033044 35 25 2,000 1,362E-03 0,03165246 ! regulation of lipid metabolic process GO:0019216 84 56 3,000 1,526E-03 0,03509835 ! regulation of binding GO:0051098 151 95 4,000 1,567E-03 0,0356928 ! carbohydrate phosphorylation GO:0046835 8 7 1,000 1,593E-03 0,03592125 ! oxaloacetate metabolic process GO:0006107 9 7 1,000 1,593E-03 0,0355725 ! lymph node development GO:0048535 9 7 1,000 1,593E-03 0,03523046 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 1,000 1,593E-03 0,03489493 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 1,000 1,593E-03 0,03456573 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 1,000 1,593E-03 0,03424269 ! erythrocyte differentiation GO:0030218 38 28 2,000 1,903E-03 0,04053108 ! regulation of B cell activation GO:0050864 42 28 2,000 1,903E-03 0,04015924 ! homeostasis of number of cells GO:0048872 84 61 3,000 2,095E-03 0,043811 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 2,112E-03 0,04375569 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 2,112E-03 0,04336502 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 2,112E-03 0,04298126 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 2,112E-03 0,04260423 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 2,112E-03 0,04223376 ! negative regulation of cell growth GO:0030308 106 62 3,000 2,225E-03 0,04410763 ! spindle organization GO:0007051 37 30 2,000 2,328E-03 0,04577022 ! negative regulation of cell size GO:0045792 108 64 3,000 2,499E-03 0,04871623 ! SMAD protein nuclear translocation GO:0007184 15 9 1,000 2,699E-03 0,05217038 ! indolalkylamine metabolic process GO:0006586 14 9 1,000 2,699E-03 0,05173563 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 1,000 2,699E-03 0,05130806 ! regulation of lipoprotein lipase activity GO:0051004 18 9 1,000 2,699E-03 0,05088751 ! base-excision repair, AP site formation GO:0006285 12 9 1,000 2,699E-03 0,05047379 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 1,000 2,699E-03 0,05006674 GO:0002820|negative regulation of adaptive immune response, ! pyridine nucleotide biosynthetic process GO:0019363 11 9 1,000 2,699E-03 0,04966621 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 1,000 2,699E-03 0,04927203 ! establishment of cell polarity GO:0030010 12 9 1,000 2,699E-03 0,04888406 ! meiosis I GO:0007127 52 32 2,000 2,808E-03 0,0504538 ! androgen receptor signaling pathway GO:0030521 54 33 2,000 3,069E-03 0,05471398 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 2,000 3,069E-03 0,05429311 ! erythrocyte homeostasis GO:0034101 45 34 2,000 3,344E-03 0,05871196 ! cortical actin cytoskeleton organization GO:0030866 19 10 1,000 3,354E-03 0,0584491 ! thyroid gland development GO:0030878 19 10 1,000 3,354E-03 0,05800963 ! regulation of phosphatase activity GO:0010921 21 10 1,000 3,354E-03 0,05757672 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 3,354E-03 0,05715023 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 3,354E-03 0,05673001 ! negative regulation of immune effector process GO:0002698 16 10 1,000 3,354E-03 0,05631592 ! steroid biosynthetic process GO:0006694 94 71 3,000 3,644E-03 0,06073075 ! lymphocyte differentiation GO:0030098 113 71 3,000 3,644E-03 0,06029384 ! negative regulation of organelle organization GO:0010639 115 72 3,000 3,832E-03 0,06295405 ! cortical cytoskeleton organization GO:0030865 20 11 1,000 4,076E-03 0,06648985 ! double-strand break repair via homologous recombination GO:0000724 16 11 1,000 4,076E-03 0,06602161 GO:0000725|recombinational repair, ! membrane protein proteolysis GO:0033619 18 11 1,000 4,076E-03 0,06555992 GO:0006509|membrane protein ectodomain proteolysis, ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 4,076E-03 0,06510464 ! regulation of Rho GTPase activity GO:0032319 18 11 1,000 4,076E-03 0,06465565 ! aromatic amino acid family catabolic process GO:0009074 13 11 1,000 4,076E-03 0,0642128 ! biogenic amine catabolic process GO:0042402 21 11 1,000 4,076E-03 0,06377598 ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 4,076E-03 0,06334506 GO:0042130|negative regulation of T cell proliferation, ! ribonucleoside metabolic process GO:0009119 48 37 2,000 4,259E-03 0,06573945 ! negative regulation of growth GO:0045926 123 75 3,000 4,436E-03 0,06801382 ! regulation of cell morphogenesis GO:0022604 140 76 3,000 4,65E-03 0,07083311 ! lactation GO:0007595 20 12 1,000 4,863E-03 0,07358451 ! histone acetylation GO:0016573 23 12 1,000 4,863E-03 0,07310357 ! peptidyl-lysine modification GO:0018205 18 12 1,000 4,863E-03 0,07262887 ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 4,945E-03 0,07337604 ! cell growth GO:0016049 61 39 2,000 4,945E-03 0,07290568 ! B cell differentiation GO:0030183 62 40 2,000 5,311E-03 0,0778116 ! regulation of T cell differentiation GO:0045580 59 41 2,000 5,694E-03 0,08288732 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 5,714E-03 0,08265319 ! endocrine pancreas development GO:0031018 19 13 1,000 5,714E-03 0,08213661 ! glutamate metabolic process GO:0006536 18 13 1,000 5,714E-03 0,08162645 ! deoxyribonucleotide catabolic process GO:0009264 16 13 1,000 5,714E-03 0,08112258 ! NAD metabolic process GO:0019674 21 13 1,000 5,714E-03 0,08062489 ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 6,628E-03 0,09294747 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 6,628E-03 0,09238415 ! regulation of ATPase activity GO:0043462 18 14 1,000 6,628E-03 0,09182762 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 6,628E-03 0,09127776 ! regulation of cell projection organization GO:0031344 83 44 2,000 6,939E-03 0,09499657 ! regulation of mast cell proliferation GO:0070666 64 44 2,000 6,939E-03 0,09443446 ! cell cycle arrest GO:0007050 150 86 3,000 7,191E-03 0,09729582 ! lipid phosphorylation GO:0046834 23 15 1,000 7,603E-03 0,10226167 ! regulation of T cell mediated immunity GO:0002709 26 15 1,000 7,603E-03 0,10166713 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 7,603E-03 0,10107946 ! cellular amino acid derivative catabolic process GO:0042219 27 15 1,000 7,603E-03 0,10049854 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 1,000 7,603E-03 0,09992426 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 7,603E-03 0,09935651 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! endocrine system development GO:0035270 83 47 2,000 8,333E-03 0,10828357 ! regulation of leukocyte proliferation GO:0070663 71 47 2,000 8,333E-03 0,10767524 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! protein amino acid acetylation GO:0006473 28 16 1,000 8,639E-03 0,11100163 ! regulation of dephosphorylation GO:0035303 33 16 1,000 8,639E-03 0,11038496 ! negative regulation of immune response GO:0050777 28 16 1,000 8,639E-03 0,1097751 ! regulation of lymphocyte differentiation GO:0045619 69 48 2,000 8,832E-03 0,11160985 ! DNA recombination GO:0006310 146 92 3,000 9,085E-03 0,11418548 ! heterocycle catabolic process GO:0046700 72 49 2,000 9,347E-03 0,1168436 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 1,000 9,734E-03 0,12101845 GO:0019692|deoxyribose phosphate metabolic process, ! aromatic compound catabolic process GO:0019439 22 17 1,000 9,734E-03 0,12036781 ! regulation of cellular component biogenesis GO:0044087 158 96 3,000 0,01051276 0,12930129 ! pancreas development GO:0031016 26 18 1,000 0,01088762 0,13319964 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 0,01088762 0,13249488 ! somitogenesis GO:0001756 24 18 1,000 0,01088762 0,13179754 ! purine nucleotide catabolic process GO:0006195 26 18 1,000 0,01088762 0,1311075 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 0,01088762 0,13042464 ! negative regulation of T cell activation GO:0050868 25 18 1,000 0,01088762 0,12974887 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 0,01209831 0,14343353 ! calcium-independent cell-cell adhesion GO:0016338 21 19 1,000 0,01209831 0,14269797 ! D-ribose metabolic process GO:0006014 25 19 1,000 0,01209831 0,14196992 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 0,01209831 0,14124926 ! apoptotic nuclear changes GO:0030262 24 19 1,000 0,01209831 0,14053588 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 0,01209831 0,13982967 ! aromatic amino acid family metabolic process GO:0009072 24 19 1,000 0,01209831 0,13913052 ! regulation of mitosis GO:0007088 84 54 2,000 0,0121872 0,13945547 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 66 54 2,000 0,0121872 0,1387651 ! cellular amino acid catabolic process GO:0009063 74 54 2,000 0,0121872 0,13808153 ! nucleoside metabolic process GO:0009116 69 55 2,000 0,01280799 0,14440382 ! response to vitamin GO:0033273 29 20 1,000 0,01336505 0,14994939 ! response to ethanol GO:0045471 37 20 1,000 0,01336505 0,14922148 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 0,01336505 0,1485006 ! DNA modification GO:0006304 28 20 1,000 0,01336505 0,14778666 ! positive regulation of B cell activation GO:0050871 31 20 1,000 0,01336505 0,14707954 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 1,000 0,01336505 0,14637916 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 1,000 0,01336505 0,14568542 ! DNA damage response, signal transduction GO:0042770 96 56 2,000 0,01344659 0,14588285 ! regulation of cell killing GO:0031341 34 21 1,000 0,01468679 0,15858974 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 0,01468679 0,15784867 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 0,01468679 0,15711449 ! protein amino acid acylation GO:0043543 37 21 1,000 0,01468679 0,15638711 ! regulation of DNA recombination GO:0000018 40 21 1,000 0,01468679 0,15566643 ! deoxyribonucleotide metabolic process GO:0009262 27 21 1,000 0,01468679 0,15495236 ! fatty acid transport GO:0015908 30 21 1,000 0,01468679 0,15424482 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 0,01468679 0,15354371 ! response to cytokine stimulus GO:0034097 47 21 1,000 0,01468679 0,15284894 ! glutamine family amino acid catabolic process GO:0009065 30 21 1,000 0,01468679 0,15216043 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 0,01606245 0,16566653 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 0,01606245 0,16492695 ! viral genome replication GO:0019079 29 22 1,000 0,01606245 0,16419394 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 0,01606245 0,16346742 GO:0010810|regulation of cell-substrate adhesion, ! barbed-end actin filament capping GO:0051016 33 22 1,000 0,01606245 0,1627473 GO:0051693|actin filament capping, ! vitamin biosynthetic process GO:0009110 24 22 1,000 0,01606245 0,16203349 ! aspartate family amino acid metabolic process GO:0009066 24 22 1,000 0,01606245 0,16132592 ! pentose metabolic process GO:0019321 31 23 1,000 0,01749099 0,17490991 ! amine catabolic process GO:0009310 90 62 2,000 0,01765554 0,1757911 ! regulation of transcription factor activity GO:0051090 97 63 2,000 0,01842036 0,18261561 GO:0090046|regulation of transcription regulator activity, ! insulin receptor signaling pathway GO:0008286 40 24 1,000 0,01897138 0,1872711 ! base-excision repair GO:0006284 31 24 1,000 0,01897138 0,1864708 ! cell cycle checkpoint GO:0000075 108 64 2,000 0,01920336 0,18794776 ! B cell activation GO:0042113 104 65 2,000 0,02000456 0,19495972 ! negative regulation of actin filament depolymerization GO:0030835 36 25 1,000 0,02050259 0,19897028 ! negative regulation of actin filament polymerization GO:0030837 36 25 1,000 0,02050259 0,19813427 ! positive regulation of nuclear division GO:0051785 39 25 1,000 0,02050259 0,19730526 GO:0045840|positive regulation of mitosis, ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 0,02050259 0,19648315 ! negative regulation of protein modification process GO:0031400 50 26 1,000 0,02208362 0,21075657 ! nicotinamide metabolic process GO:0006769 39 26 1,000 0,02208362 0,20988568 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of protein polymerization GO:0032272 38 26 1,000 0,02208362 0,20902195 ! intracellular protein transmembrane transport GO:0065002 102 68 2,000 0,02251754 0,21225552 ! alkaloid metabolic process GO:0009820 40 27 1,000 0,02371349 0,22261641 ! regulation of actin filament depolymerization GO:0030834 39 27 1,000 0,02371349 0,22171146 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 1,000 0,02371349 0,22081384 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 0,02371349 0,21992347 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 0,02371349 0,21904024 GO:0043433|negative regulation of transcription factor activity, ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 2,000 0,02519464 0,23179072 ! complement activation, classical pathway GO:0006958 36 28 1,000 0,0253912 0,23266838 ! positive regulation of T cell differentiation GO:0045582 39 28 1,000 0,0253912 0,23174509 ! positive regulation of multicellular organism growth GO:0040018 38 28 1,000 0,0253912 0,2308291 ! pyridine nucleotide metabolic process GO:0019362 41 28 1,000 0,0253912 0,22992033 ! positive regulation of lymphocyte activation GO:0051251 108 74 2,000 0,02803565 0,25287053 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 1,000 0,02888634 0,25952568 ! adult locomotory behavior GO:0008344 47 30 1,000 0,02888634 0,25851586 ! negative regulation of cell activation GO:0050866 44 30 1,000 0,02888634 0,25751386 ! regulation of ligase activity GO:0051340 114 75 2,000 0,02901898 0,25769748 ! cofactor biosynthetic process GO:0051188 92 75 2,000 0,02901898 0,25670634 ! mammary gland development GO:0030879 57 31 1,000 0,03070187 0,27055286 ! xenobiotic metabolic process GO:0006805 44 31 1,000 0,03070187 0,26952021 ! segmentation GO:0035282 41 31 1,000 0,03070187 0,26849542 ! metanephros development GO:0001656 58 31 1,000 0,03070187 0,26747839 ! gland development GO:0048732 148 77 2,000 0,03103996 0,26940345 ! protein ubiquitination GO:0016567 125 77 2,000 0,03103996 0,26839066 ! nitrogen compound catabolic process GO:0044270 114 78 2,000 0,03207754 0,27632342 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 0,03256147 0,27944543 ! regulation of protein stability GO:0031647 48 32 1,000 0,03256147 0,2784066 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 1,000 0,03256147 0,27737547 ! T cell activation GO:0042110 134 79 2,000 0,03313313 0,28120369 ! regulation of GTPase activity GO:0043087 129 80 2,000 0,03420668 0,28924762 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 0,03446422 0,29035793 ! sister chromatid segregation GO:0000819 46 33 1,000 0,03446422 0,28929823 ! nucleus organization GO:0006997 49 33 1,000 0,03446422 0,28824624 ! negative regulation of DNA binding GO:0043392 54 33 1,000 0,03446422 0,28720187 ! nucleotide catabolic process GO:0009166 46 33 1,000 0,03446422 0,28616504 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 0,03446422 0,28513567 ! positive regulation of cell activation GO:0050867 120 81 2,000 0,03529813 0,29098816 GO:0002696|positive regulation of leukocyte activation, ! detection of stimulus GO:0051606 108 82 2,000 0,03640744 0,29906111 ! neuron migration GO:0001764 46 34 1,000 0,03640924 0,29801155 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 0,03640924 0,29695477 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,03839562 0,31204918 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! microtubule cytoskeleton organization GO:0000226 120 84 2,000 0,0386794 0,31324867 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,04042249 0,32621656 GO:0090047|positive regulation of transcription regulator activity, ! cellular amide metabolic process GO:0043603 52 36 1,000 0,04042249 0,32507594 ! negative regulation of binding GO:0051100 58 36 1,000 0,04042249 0,32394327 ! response to xenobiotic stimulus GO:0009410 50 36 1,000 0,04042249 0,32281847 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 2,000 0,04221975 0,33600491 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 1,000 0,04248898 0,3369816 GO:0006956|complement activation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 1,000 0,04248898 0,33582359 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 2,000 0,0434349 0,34212418 ! carboxylic acid catabolic process GO:0046395 122 88 2,000 0,0434349 0,34095652 GO:0016054|organic acid catabolic process, ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,04355704 0,34075235 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,04355704 0,33959726 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,04355704 0,33844997 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,04355704 0,33731041 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,04355704 0,3361785 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,04355704 0,33505415 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,04355704 0,33393731 ! sleep GO:0030431 11 5 0,000 0,04355704 0,33282788 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,04355704 0,3317258 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,04355704 0,330631 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,04355704 0,3295434 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,04355704 0,32846293 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,04355704 0,32738952 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,04355704 0,3263231 ! tongue development GO:0043586 6 5 0,000 0,04355704 0,32526361 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,04355704 0,32421098 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,04355704 0,32316514 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,04355704 0,32212602 ! cobalt ion transport GO:0006824 9 5 0,000 0,04355704 0,32109356 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,04355704 0,32006771 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,04355704 0,31904838 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,04355704 0,31803553 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,04355704 0,31702909 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,04355704 0,316029 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,04355704 0,3150352 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,04355704 0,31404762 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,04355704 0,31306623 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,04355704 0,31209094 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,04355704 0,31112171 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,04355704 0,31015849 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,04355704 0,30920121 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,04355704 0,30824982 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,04355704 0,30730427 ! malate metabolic process GO:0006108 7 5 0,000 0,04355704 0,3063645 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,04355704 0,30543046 ! behavioral response to pain GO:0048266 7 5 0,000 0,04355704 0,3045021 ! clathrin coat assembly GO:0048268 11 5 0,000 0,04355704 0,30357937 ! phototransduction, visible light GO:0007603 6 5 0,000 0,04355704 0,30266221 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,04355704 0,30175058 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,04355704 0,30084442 ! mating behavior GO:0007617 6 5 0,000 0,04355704 0,29994369 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,04355704 0,29904833 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,04355704 0,29815831 ! rhythmic behavior GO:0007622 12 5 0,000 0,04355704 0,29727357 ! copulation GO:0007620 7 5 0,000 0,04355704 0,29639406 ! glial cell fate commitment GO:0021781 12 5 0,000 0,04355704 0,29551974 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,04355704 0,29465057 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,04355704 0,29378649 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,04355704 0,29292746 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,04355704 0,29207345 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,04355704 0,2912244 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,04355704 0,29038027 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,04355704 0,28954102 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,04355704 0,28870661 ! response to protozoan GO:0001562 9 5 0,000 0,04355704 0,28787699 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,04355704 0,28705213 ! lymph vessel development GO:0001945 7 5 0,000 0,04355704 0,28623198 ! endochondral ossification GO:0001958 12 5 0,000 0,04355704 0,2854165 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,04355704 0,28460566 ! parathyroid gland development GO:0060017 8 5 0,000 0,04355704 0,28379941 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,04355704 0,28299772 ! anagen GO:0042640 6 5 0,000 0,04355704 0,28220054 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,04355704 0,28140784 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,04355704 0,28061959 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,04355704 0,27983573 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,04355704 0,27905625 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,04355704 0,27828109 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,04355704 0,27751023 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,04355704 0,27674362 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,04355704 0,27598125 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,04355704 0,27522306 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,04355704 0,27446902 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,04355704 0,2737191 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,04355704 0,27297328 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,04355704 0,2722315 ! ovulation GO:0030728 6 5 0,000 0,04355704 0,27149375 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,04355704 0,27075998 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,04355704 0,27003017 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,04355704 0,26930428 ! response to pH GO:0009268 9 5 0,000 0,04355704 0,26858228 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,04355704 0,26786415 ! proline biosynthetic process GO:0006561 6 5 0,000 0,04355704 0,26714985 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,04355704 0,26643934 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,04355704 0,26573261 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,04355704 0,26502961 ! polyol catabolic process GO:0046174 7 5 0,000 0,04355704 0,26433032 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,04355704 0,26363472 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,04355704 0,26294276 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,04355704 0,26225443 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,04355704 0,26156969 ! nerve growth factor processing GO:0032455 7 5 0,000 0,04355704 0,26088852 ! urea metabolic process GO:0019627 6 5 0,000 0,04355704 0,26021089 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,04355704 0,25953677 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,04355704 0,25886613 ! neutrophil activation GO:0042119 5 5 0,000 0,04355704 0,25819895 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,04355704 0,2575352 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,04355704 0,25687485 ! response to food GO:0032094 5 5 0,000 0,04355704 0,25621788 ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,04355704 0,25556427 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,04355704 0,25491398 ! forebrain neuron development GO:0021884 7 5 0,000 0,04355704 0,25426699 ! melanosome organization GO:0032438 7 5 0,000 0,04355704 0,25362327 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,04355704 0,25298281 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,04355704 0,25234557 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,04355704 0,25171154 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,04355704 0,25108068 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,04355704 0,25045298 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,04355704 0,24982841 ! nucleoside transport GO:0015858 6 5 0,000 0,04355704 0,24920695 ! nucleoside salvage GO:0043174 7 5 0,000 0,04355704 0,24858857 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,04355704 0,24797325 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,04355704 0,24736097 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,04355704 0,2467517 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,04355704 0,24614544 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,04355704 0,24554214 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,04355704 0,24494179 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,04355704 0,24434437 ! depyrimidination GO:0045008 8 5 0,000 0,04355704 0,24374986 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,04355704 0,24315823 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,04355704 0,24256947 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,04355704 0,24198356 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,04355704 0,24140046 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,04355704 0,24082017 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,04355704 0,24024267 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,04355704 0,23966792 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,04355704 0,23909592 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,04355704 0,23852665 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,04355704 0,23796008 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,04355704 0,23739619 ! centrosome duplication GO:0051298 5 5 0,000 0,04355704 0,23683497 ! response to UV-C GO:0010225 6 5 0,000 0,04355704 0,2362764 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,04355704 0,23572045 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,04355704 0,23516712 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,04355704 0,23461638 ! regulation of dendrite development GO:0050773 12 5 0,000 0,04355704 0,23406821 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,04355704 0,23352259 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,04355704 0,23297952 ! melanosome transport GO:0032402 8 5 0,000 0,04355704 0,23243896 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,04355704 0,23190091 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,04355704 0,23136534 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,04355704 0,23083224 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,04355704 0,23030159 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,04355704 0,22977338 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,04355704 0,22924758 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,04355704 0,22872418 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,04355704 0,22820317 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,04355704 0,22768453 ! neural tube patterning GO:0021532 6 5 0,000 0,04355704 0,22716824 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,04355704 0,22665428 ! histone demethylation GO:0016577 9 5 0,000 0,04355704 0,22614265 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,04355704 0,22563332 ! regulation of sterol transport GO:0032371 7 5 0,000 0,04355704 0,22512627 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,04355704 0,22462151 ! enteric nervous system development GO:0048484 8 5 0,000 0,04355704 0,224119 ! establishment of planar polarity GO:0001736 6 5 0,000 0,04355704 0,22361873 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,04355704 0,2231207 ! muscle cell proliferation GO:0033002 8 5 0,000 0,04355704 0,22262487 ! transcription termination GO:0006353 8 5 0,000 0,04355704 0,22213125 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,04355704 0,22163981 ! plasminogen activation GO:0031639 5 5 0,000 0,04355704 0,22115053 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,04355704 0,22066342 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,04355704 0,22017844 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,04355704 0,2196956 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,04355704 0,21921486 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,04355704 0,21873623 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,04355704 0,21825968 ! apical protein localization GO:0045176 6 5 0,000 0,04355704 0,2177852 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,04355704 0,21731278 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,04355704 0,21684241 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,04355704 0,21637407 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,04355704 0,21590774 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,04355704 0,21544342 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,04355704 0,2149811 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,04355704 0,21452075 ! glial cell migration GO:0008347 10 5 0,000 0,04355704 0,21406238 ! determination of adult lifespan GO:0008340 8 5 0,000 0,04355704 0,21360595 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,04355704 0,21315147 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,04355704 0,21269892 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,04355704 0,21224829 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,04355704 0,21179956 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,04355704 0,21135273 ! neural plate development GO:0001840 6 5 0,000 0,04355704 0,21090777 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,04355704 0,21046469 ! regulation of sensory perception GO:0051931 6 5 0,000 0,04355704 0,21002346 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,04355704 0,20958408 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,04355704 0,20914654 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,04355704 0,20871082 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,04355704 0,20827691 ! sensory cilium assembly GO:0035058 6 5 0,000 0,04355704 0,2078448 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,04355704 0,20741448 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,04355704 0,20698593 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,04355704 0,20655916 ! spindle assembly GO:0051225 5 5 0,000 0,04355704 0,20613414 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,04355704 0,20571087 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,04355704 0,20528933 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,04355704 0,20486951 ! organ regeneration GO:0031100 7 5 0,000 0,04355704 0,20445141 ! carnitine metabolic process GO:0009437 5 5 0,000 0,04355704 0,20403501 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,04355704 0,20362031 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,04355704 0,20320729 GO:0055081|anion homeostasis, ! monocarboxylic acid transport GO:0015718 62 38 1,000 0,04459426 0,20762509 ! regulation of T cell proliferation GO:0042129 58 38 1,000 0,04459426 0,20720564 ! pigmentation GO:0043473 74 38 1,000 0,04459426 0,20678789 ! striated muscle cell differentiation GO:0051146 54 38 1,000 0,04459426 0,20637182 ! mesenchymal cell development GO:0014031 64 38 1,000 0,04459426 0,20595742 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 2,000 0,04466744 0,20588198 ! regulation of T cell activation GO:0050863 128 89 2,000 0,04466744 0,20547022 ! protein modification by small protein conjugation GO:0032446 140 90 2,000 0,0459173 0,21079797 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,04673747 0,2141358 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 1,000 0,04673747 0,21371008 ! chromatin remodeling GO:0006338 68 39 1,000 0,04673747 0,21328606 ! regulation of actin filament polymerization GO:0030833 59 40 1,000 0,04891778 0,22279385 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 0,04891778 0,22235355 ! T cell differentiation GO:0030217 65 40 1,000 0,04891778 0,22191498 ! double-strand break repair GO:0006302 67 40 1,000 0,04891778 0,22147814 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 0,04891778 0,22104302 ! regulation of leukocyte mediated immunity GO:0002703 62 41 1,000 0,05113438 0,23060605 ! tRNA transcription GO:0009304 11 6 0,000 0,05203954 0,23422885 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,05203954 0,23377137 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,05203954 0,23331568 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,05203954 0,23286176 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,05203954 0,2324096 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,05203954 0,23195919 ! regulation of helicase activity GO:0051095 11 6 0,000 0,05203954 0,23151053 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,05203954 0,2310636 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,05203954 0,23061839 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,05203954 0,23017489 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,05203954 0,2297331 ! prostate gland development GO:0030850 9 6 0,000 0,05203954 0,22929299 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,05203954 0,22885458 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,05203954 0,22841783 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,05203954 0,22798275 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,05203954 0,22754932 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,05203954 0,22711754 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,05203954 0,22668739 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,05203954 0,22625887 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,05203954 0,22583197 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,05203954 0,22540667 ! neuron adhesion GO:0007158 9 6 0,000 0,05203954 0,22498298 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,05203954 0,22456087 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,05203954 0,22414034 ! signal peptide processing GO:0006465 8 6 0,000 0,05203954 0,22372139 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,05203954 0,223304 ! mRNA stabilization GO:0048255 15 6 0,000 0,05203954 0,22288816 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,05203954 0,22247387 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,05203954 0,22206112 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,05203954 0,22164989 ! opsonization GO:0008228 8 6 0,000 0,05203954 0,22124019 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,05203954 0,220832 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,05203954 0,22042531 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,05203954 0,22002012 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,05203954 0,21961641 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,05203954 0,21921418 ! photoreceptor cell development GO:0042461 10 6 0,000 0,05203954 0,21881342 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,05203954 0,21841413 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,05203954 0,21801629 ! mechanosensory behavior GO:0007638 8 6 0,000 0,05203954 0,2176199 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,05203954 0,21722494 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,05203954 0,21683142 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,05203954 0,21643932 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,05203954 0,21604863 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,05203954 0,21565936 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,05203954 0,21527148 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,05203954 0,214885 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,05203954 0,2144999 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,05203954 0,21411618 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,05203954 0,21373383 ! thymic T cell selection GO:0045061 12 6 0,000 0,05203954 0,21335284 ! protein lipoylation GO:0009249 10 6 0,000 0,05203954 0,21297321 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,05203954 0,21259493 ! pigment granule organization GO:0048753 11 6 0,000 0,05203954 0,21221798 ! drug transport GO:0015893 6 6 0,000 0,05203954 0,21184238 ! cysteine metabolic process GO:0006534 7 6 0,000 0,05203954 0,2114681 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,05203954 0,21109514 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,05203954 0,21072349 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,05203954 0,21035315 ! histidine metabolic process GO:0006547 6 6 0,000 0,05203954 0,20998411 GO:0009075|histidine family amino acid metabolic process, ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,05203954 0,20961636 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,05203954 0,2092499 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,05203954 0,20888472 ! adenohypophysis development GO:0021984 10 6 0,000 0,05203954 0,20852081 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,05203954 0,20815816 ! hyperosmotic response GO:0006972 8 6 0,000 0,05203954 0,20779678 ! microtubule nucleation GO:0007020 10 6 0,000 0,05203954 0,20743664 ! ER overload response GO:0006983 7 6 0,000 0,05203954 0,20707776 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,05203954 0,20672011 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,05203954 0,20636369 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,05203954 0,20600851 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,05203954 0,20565454 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,05203954 0,20530179 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 0,05203954 0,20495024 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,05203954 0,2045999 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,05203954 0,20425076 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,05203954 0,2039028 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,05203954 0,20355603 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,05203954 0,20321043 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,05203954 0,20286601 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,05203954 0,20252275 ! neuron apoptosis GO:0051402 8 6 0,000 0,05203954 0,20218065 ! organic alcohol transport GO:0015850 9 6 0,000 0,05203954 0,2018397 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,05203954 0,2014999 ! T cell mediated immunity GO:0002456 12 6 0,000 0,05203954 0,20116125 ! male sex determination GO:0030238 9 6 0,000 0,05203954 0,20082373 ! carnitine transport GO:0015879 8 6 0,000 0,05203954 0,20048734 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,05203954 0,20015208 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,05203954 0,19981793 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,05203954 0,19948491 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,05203954 0,19915298 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,05203954 0,19882216 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,05203954 0,19849244 ! parturition GO:0007567 12 6 0,000 0,05203954 0,19816381 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,05203954 0,19783627 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,05203954 0,19750981 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,05203954 0,19718442 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,05203954 0,1968601 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,05203954 0,19653685 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,05203954 0,19621466 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,05203954 0,19589352 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,05203954 0,19557344 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,05203954 0,19525439 ! astrocyte development GO:0014002 14 6 0,000 0,05203954 0,19493639 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,05203954 0,19461942 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,05203954 0,19430348 ! interaction with symbiont GO:0051702 8 6 0,000 0,05203954 0,19398856 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,05203954 0,19367467 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,05203954 0,19336178 ! eating behavior GO:0042755 6 6 0,000 0,05203954 0,19304991 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,05203954 0,19273904 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,05203954 0,19242917 ! response to copper ion GO:0046688 9 6 0,000 0,05203954 0,19212029 ! DNA topological change GO:0006265 8 6 0,000 0,05203954 0,19181241 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,05203954 0,19150551 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,05203954 0,19119959 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,05203954 0,19089465 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,05203954 0,19059067 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,05203954 0,19028767 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,05203954 0,18998562 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,05203954 0,18968454 ! gas homeostasis GO:0033483 11 6 0,000 0,05203954 0,1893844 ! hair follicle maturation GO:0048820 7 6 0,000 0,05203954 0,18908522 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,05203954 0,18878698 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,05203954 0,18848967 ! Schwann cell development GO:0014044 14 6 0,000 0,05203954 0,18819331 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,05203954 0,18789787 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,05203954 0,18760336 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,05203954 0,18730977 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,05203954 0,1870171 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,05203954 0,18672534 ! histone ubiquitination GO:0016574 7 6 0,000 0,05203954 0,18643449 ! regulation of meiosis GO:0040020 10 6 0,000 0,05203954 0,18614455 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,05203954 0,1858555 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,05203954 0,18556735 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,05203954 0,1852801 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,05203954 0,18499373 ! membrane to membrane docking GO:0022614 12 6 0,000 0,05203954 0,18470825 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,05203954 0,18442364 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,05203954 0,18413991 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,05203954 0,18385706 ! receptor internalization GO:0031623 9 6 0,000 0,05203954 0,18357507 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,05203954 0,18329394 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,05203954 0,18301367 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,05203954 0,18273426 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,05203954 0,18245571 ! protein deubiquitination GO:0016579 8 6 0,000 0,05203954 0,182178 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,05203954 0,18190113 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,05203954 0,1816251 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,05203954 0,18134991 ! axonal fasciculation GO:0007413 9 6 0,000 0,05203954 0,18107556 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,05203954 0,18080203 ! thiamin metabolic process GO:0006772 6 6 0,000 0,05203954 0,18052933 ! midbrain development GO:0030901 6 6 0,000 0,05203954 0,18025744 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,05203954 0,17998638 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,05203954 0,17971613 ! progesterone metabolic process GO:0042448 8 6 0,000 0,05203954 0,17944669 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,05203954 0,17917806 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,05203954 0,17891023 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,05203954 0,1786432 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,05203954 0,17837696 ! adult feeding behavior GO:0008343 6 6 0,000 0,05203954 0,17811152 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,05203954 0,17784687 ! blastocyst growth GO:0001832 15 6 0,000 0,05203954 0,177583 ! pigment granule transport GO:0051904 12 6 0,000 0,05203954 0,17731992 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,05203954 0,17705761 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,05203954 0,17679608 ! catecholamine transport GO:0051937 7 6 0,000 0,05203954 0,17653531 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,05203954 0,17627532 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,05203954 0,17601609 ! protein prenylation GO:0018342 10 6 0,000 0,05203954 0,17575763 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,05203954 0,17549992 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,05203954 0,17524296 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,05203954 0,17498676 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,05203954 0,1747313 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,05203954 0,17447659 ! cellular component disassembly GO:0022411 64 42 1,000 0,05338647 0,17873201 ! protein modification by small protein conjugation or removal GO:0070647 148 96 2,000 0,05377534 0,17977222 ! leukocyte migration GO:0050900 60 43 1,000 0,05567325 0,18584685 ! activation of caspase activity GO:0006919 65 43 1,000 0,05567325 0,1855775 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 1,000 0,05567325 0,18530894 ! response to insulin stimulus GO:0032868 63 43 1,000 0,05567325 0,18504115 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 0,05793098 0,19226731 ! activation of adenylate cyclase activity GO:0007190 76 44 1,000 0,05799394 0,19219892 ! glycolysis GO:0006096 53 44 1,000 0,05799394 0,19192238 ! cellular amino acid biosynthetic process GO:0008652 51 44 1,000 0,05799394 0,19164663 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 2,000 0,05934911 0,19584354 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,06034775 0,19885363 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 0,06034775 0,19856915 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,06044729 0,19861253 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,06044729 0,1983292 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,06044729 0,19804668 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,06044729 0,19776497 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,06044729 0,19748405 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,06044729 0,19720393 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,06044729 0,19692461 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,06044729 0,19664607 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,06044729 0,19636832 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,06044729 0,19609136 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,06044729 0,19581517 ! reproductive behavior GO:0019098 12 7 0,000 0,06044729 0,19553976 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,06044729 0,19526513 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,06044729 0,19499127 ! oligopeptide transport GO:0006857 11 7 0,000 0,06044729 0,19471817 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,06044729 0,19444584 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,06044729 0,19417426 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,06044729 0,19390345 ! RNA methylation GO:0001510 11 7 0,000 0,06044729 0,19363339 ! pericardium development GO:0060039 8 7 0,000 0,06044729 0,19336408 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,06044729 0,19309552 ! fibril organization GO:0043206 13 7 0,000 0,06044729 0,1928277 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,06044729 0,19256063 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,06044729 0,19229429 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,06044729 0,19202869 ! lipoprotein transport GO:0042953 9 7 0,000 0,06044729 0,19176382 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,06044729 0,19149969 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,06044729 0,19123628 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,06044729 0,19097359 ! estrogen metabolic process GO:0008210 14 7 0,000 0,06044729 0,19071162 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,06044729 0,19045037 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,06044729 0,19018984 ! chemosensory behavior GO:0007635 9 7 0,000 0,06044729 0,18993002 ! microtubule bundle formation GO:0001578 8 7 0,000 0,06044729 0,1896709 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,06044729 0,1894125 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,06044729 0,18915479 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,06044729 0,18889779 ! leukocyte degranulation GO:0043299 10 7 0,000 0,06044729 0,18864148 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,06044729 0,18838587 ! reflex GO:0060004 12 7 0,000 0,06044729 0,18813095 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,06044729 0,18787672 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,06044729 0,18762317 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,06044729 0,18737031 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,06044729 0,18711813 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,06044729 0,18686663 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,06044729 0,1866158 ! spinal cord patterning GO:0021511 7 7 0,000 0,06044729 0,18636565 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,06044729 0,18611616 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,06044729 0,18586734 ! adrenal gland development GO:0030325 17 7 0,000 0,06044729 0,18561919 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,06044729 0,1853717 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,06044729 0,18512486 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,06044729 0,18487869 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,06044729 0,18463316 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,06044729 0,18438829 ! endosome organization GO:0007032 10 7 0,000 0,06044729 0,18414407 ! thyroid hormone generation GO:0006590 11 7 0,000 0,06044729 0,18390049 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,06044729 0,18365756 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,06044729 0,18341527 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,06044729 0,18317361 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,06044729 0,1829326 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,06044729 0,18269221 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,06044729 0,18245246 ! galactose metabolic process GO:0006012 10 7 0,000 0,06044729 0,18221333 ! vesicle fusion GO:0006906 15 7 0,000 0,06044729 0,18197483 ! intracellular pH reduction GO:0051452 10 7 0,000 0,06044729 0,18173696 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,06044729 0,1814997 ! organ growth GO:0035265 11 7 0,000 0,06044729 0,18126307 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,06044729 0,18102705 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,06044729 0,18079164 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,06044729 0,18055685 ! retinol metabolic process GO:0042572 9 7 0,000 0,06044729 0,18032266 ! behavioral fear response GO:0001662 13 7 0,000 0,06044729 0,18008908 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,06044729 0,17985611 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,06044729 0,17962374 ! rRNA modification GO:0000154 12 7 0,000 0,06044729 0,17939196 ! protein heterooligomerization GO:0051291 10 7 0,000 0,06044729 0,17916079 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,06044729 0,17893021 ! response to UV-B GO:0010224 11 7 0,000 0,06044729 0,17870022 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,06044729 0,17847082 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,06044729 0,17824202 ! intermediate filament organization GO:0045109 11 7 0,000 0,06044729 0,17801379 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,06044729 0,17778615 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,06044729 0,1775591 ! fibrinolysis GO:0042730 9 7 0,000 0,06044729 0,17733262 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,06044729 0,17710672 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,06044729 0,17688139 ! B cell lineage commitment GO:0002326 17 7 0,000 0,06044729 0,17665664 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,06044729 0,17643245 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,06044729 0,17620884 ! response to tropane GO:0014073 13 7 0,000 0,06044729 0,17598579 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,06044729 0,1757633 ! melanosome localization GO:0032400 10 7 0,000 0,06044729 0,17554138 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,06044729 0,17532002 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,06044729 0,17509921 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,06044729 0,17487896 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,06044729 0,17465926 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,06044729 0,17444012 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,06044729 0,17422152 ! mast cell activation GO:0045576 9 7 0,000 0,06044729 0,17400347 ! multicellular organismal aging GO:0010259 11 7 0,000 0,06044729 0,17378597 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,06044729 0,173569 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,06044729 0,17335258 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,06044729 0,1731367 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,06044729 0,17292136 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,06044729 0,17270655 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,06044729 0,17249227 ! T cell lineage commitment GO:0002360 12 7 0,000 0,06044729 0,17227853 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,06044729 0,17206531 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,06044729 0,17185262 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,06044729 0,17164046 ! regulation of lipid transport GO:0032368 13 7 0,000 0,06044729 0,17142882 ! response to tumor cell GO:0002347 12 7 0,000 0,06044729 0,1712177 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,06044729 0,1710071 ! neuroblast proliferation GO:0007405 13 7 0,000 0,06044729 0,17079702 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,06044729 0,17058745 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,06044729 0,1703784 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,06044729 0,17016986 ! diuresis GO:0030146 12 7 0,000 0,06044729 0,16996182 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,06044729 0,1697543 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,06044729 0,16954728 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,06044729 0,16934077 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,06044729 0,16913476 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,06044729 0,16892925 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,06044729 0,16872424 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,06044729 0,16851972 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,06044729 0,1683157 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,06044729 0,16811218 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,06044729 0,16790915 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,06044729 0,1677066 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,06044729 0,16750454 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,06044729 0,16730298 ! ATP catabolic process GO:0006200 10 7 0,000 0,06044729 0,16710189 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,06044729 0,16690129 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,06044729 0,16670117 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,06044729 0,16650152 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,06044729 0,16630236 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,06044729 0,16610367 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,06044729 0,16590546 ! muscle adaptation GO:0043500 12 7 0,000 0,06044729 0,16570771 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,06044729 0,16551044 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,06044729 0,16531364 ! retina homeostasis GO:0001895 9 7 0,000 0,06044729 0,16511731 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,06044729 0,16492144 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,06044729 0,16472603 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,06044729 0,16453109 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,06044729 0,16433661 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,06044729 0,16414259 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,06044729 0,16394902 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 1,000 0,06273395 0,16995062 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,06273395 0,16975068 ! cell redox homeostasis GO:0045454 63 46 1,000 0,06273395 0,1695512 ! histone modification GO:0016570 68 46 1,000 0,06273395 0,1693522 ! regulation of adaptive immune response GO:0002819 72 46 1,000 0,06273395 0,16915366 ! response to UV GO:0009411 75 46 1,000 0,06273395 0,16895559 ! viral infectious cycle GO:0019058 71 47 1,000 0,06515176 0,17526204 ! covalent chromatin modification GO:0016569 75 47 1,000 0,06515176 0,1750573 ! positive regulation of cyclase activity GO:0031281 87 47 1,000 0,06515176 0,17485303 ! glutamine family amino acid metabolic process GO:0009064 59 47 1,000 0,06515176 0,17464924 ! regulation of protein polymerization GO:0032271 71 47 1,000 0,06515176 0,17444592 ! positive regulation of caspase activity GO:0043280 72 48 1,000 0,06760046 0,18079192 GO:0010952|positive regulation of peptidase activity, ! regulation of actin polymerization or depolymerization GO:0008064 68 48 1,000 0,06760046 0,18058194 ! immunoglobulin mediated immune response GO:0016064 66 48 1,000 0,06760046 0,18037245 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 1,000 0,06760046 0,18016344 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,06878095 0,18309744 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,06878095 0,18288576 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,06878095 0,18267458 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,06878095 0,18246388 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,06878095 0,18225367 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,06878095 0,18204394 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,06878095 0,1818347 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,06878095 0,18162593 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,06878095 0,18141764 ! phosphate transport GO:0006817 10 8 0,000 0,06878095 0,18120983 ! N-glycan processing GO:0006491 12 8 0,000 0,06878095 0,1810025 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,06878095 0,18079564 ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,06878095 0,18058925 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,06878095 0,18038334 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,06878095 0,18017789 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,06878095 0,17997291 ! succinate metabolic process GO:0006105 14 8 0,000 0,06878095 0,17976839 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,06878095 0,17956434 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,06878095 0,17936075 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,06878095 0,17915763 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,06878095 0,17895496 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,06878095 0,17875275 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,06878095 0,178551 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,06878095 0,1783497 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,06878095 0,17814886 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,06878095 0,17794846 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,06878095 0,17774852 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,06878095 0,17754903 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,06878095 0,17734998 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,06878095 0,17715138 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,06878095 0,17695323 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,06878095 0,17675551 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,06878095 0,17655824 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,06878095 0,17636141 ! astrocyte differentiation GO:0048708 16 8 0,000 0,06878095 0,17616502 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,06878095 0,17596906 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,06878095 0,17577354 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,06878095 0,17557845 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,06878095 0,1753838 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,06878095 0,17518957 ! melanin metabolic process GO:0006582 12 8 0,000 0,06878095 0,17499578 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,06878095 0,17480241 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,06878095 0,17460948 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,06878095 0,17441696 ! macrophage activation GO:0042116 12 8 0,000 0,06878095 0,17422487 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,06878095 0,17403321 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,06878095 0,17384196 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,06878095 0,17365114 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,06878095 0,17346073 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,06878095 0,17327074 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,06878095 0,17308117 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,06878095 0,17289201 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,06878095 0,17270326 ! ruffle organization GO:0031529 11 8 0,000 0,06878095 0,17251492 ! osteoblast development GO:0002076 13 8 0,000 0,06878095 0,172327 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,06878095 0,17213948 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,06878095 0,17195238 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,06878095 0,17176567 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,06878095 0,17157938 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,06878095 0,17139348 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,06878095 0,17120799 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,06878095 0,1710229 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,06878095 0,17083821 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,06878095 0,17065392 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,06878095 0,17047003 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,06878095 0,17028653 ! oligodendrocyte development GO:0014003 8 8 0,000 0,06878095 0,17010342 ! segment specification GO:0007379 10 8 0,000 0,06878095 0,16992071 ! cellular extravasation GO:0045123 11 8 0,000 0,06878095 0,1697384 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,06878095 0,16955647 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,06878095 0,16937493 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,06878095 0,16919378 ! snRNA metabolic process GO:0016073 10 8 0,000 0,06878095 0,16901302 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,06878095 0,16883264 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,06878095 0,16865265 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,06878095 0,16847304 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,06878095 0,16829381 ! nucleosome disassembly GO:0006337 12 8 0,000 0,06878095 0,16811497 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,06878095 0,1679365 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,06878095 0,16775841 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,06878095 0,1675807 ! icosanoid secretion GO:0032309 12 8 0,000 0,06878095 0,16740337 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,06878095 0,16722641 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,06878095 0,16704983 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,06878095 0,16687361 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,06878095 0,16669777 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,06878095 0,1665223 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,06878095 0,1663472 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,06878095 0,16617246 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,06878095 0,1659981 ! sterol catabolic process GO:0016127 9 8 0,000 0,06878095 0,16582409 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,06878095 0,16565046 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,06878095 0,16547718 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,06878095 0,16530427 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,06878095 0,16513172 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,06878095 0,16495953 ! prophase GO:0051324 11 8 0,000 0,06878095 0,16478769 ! S phase GO:0051320 8 8 0,000 0,06878095 0,16461622 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,06878095 0,1644451 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,06878095 0,16427434 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,06878095 0,16410393 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,06878095 0,16393387 ! hormone catabolic process GO:0042447 13 8 0,000 0,06878095 0,16376417 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,06878095 0,16359481 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,06878095 0,16342581 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,06878095 0,16325716 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,06878095 0,16308885 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,06878095 0,16292089 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,06878095 0,16275328 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,06878095 0,16258601 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,06878095 0,16241908 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,06878095 0,1622525 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,06878095 0,16208626 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,06878095 0,16192035 ! lamellipodium assembly GO:0030032 9 8 0,000 0,06878095 0,16175479 ! regulation of embryonic development GO:0045995 16 8 0,000 0,06878095 0,16158957 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,06878095 0,16142468 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,06878095 0,16126013 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,06878095 0,16109591 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 0,07007931 0,16396989 ! regulation of actin filament length GO:0030832 72 50 1,000 0,07258759 0,16966611 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,07258759 0,16949386 ! lipid modification GO:0030258 73 50 1,000 0,07258759 0,16932196 ! positive regulation of growth GO:0045927 67 50 1,000 0,07258759 0,16915041 ! regulation of multicellular organism growth GO:0040014 65 50 1,000 0,07258759 0,16897921 ! regulation of protein catabolic process GO:0042176 77 51 1,000 0,0751246 0,17470837 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,0751246 0,1745319 ! adult behavior GO:0030534 80 51 1,000 0,0751246 0,17435578 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,07704116 0,17862366 ! regulation of developmental growth GO:0048638 13 9 0,000 0,07704116 0,17844378 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,07704116 0,17826426 ! telencephalon cell migration GO:0022029 16 9 0,000 0,07704116 0,1780851 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,07704116 0,1779063 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,07704116 0,17772786 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,07704116 0,17754977 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,07704116 0,17737205 GO:0010469|regulation of receptor activity, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,07704116 0,17719467 ! elastic fiber assembly GO:0048251 13 9 0,000 0,07704116 0,17701766 ! social behavior GO:0035176 14 9 0,000 0,07704116 0,17684099 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,07704116 0,17666468 ! artery development GO:0060840 19 9 0,000 0,07704116 0,17648872 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,07704116 0,17631311 ! regulation of glycolysis GO:0006110 15 9 0,000 0,07704116 0,17613785 ! response to pain GO:0048265 16 9 0,000 0,07704116 0,17596293 ! protein complex disassembly GO:0043241 17 9 0,000 0,07704116 0,17578837 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,07704116 0,17561415 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,07704116 0,17544027 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,07704116 0,17526674 ! lung alveolus development GO:0048286 17 9 0,000 0,07704116 0,17509355 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,07704116 0,1749207 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,07704116 0,1747482 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,07704116 0,17457603 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,07704116 0,17440421 ! ventral spinal cord development GO:0021517 11 9 0,000 0,07704116 0,17423272 ! protein targeting to ER GO:0045047 19 9 0,000 0,07704116 0,17406157 ! T cell selection GO:0045058 18 9 0,000 0,07704116 0,17389075 ! endoderm development GO:0007492 12 9 0,000 0,07704116 0,17372027 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,07704116 0,17355012 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,07704116 0,17338031 ! arginine catabolic process GO:0006527 10 9 0,000 0,07704116 0,17321082 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,07704116 0,17304167 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,07704116 0,17287285 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,07704116 0,17270436 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,07704116 0,1725362 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,07704116 0,17236836 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,07704116 0,17220085 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,07704116 0,17203366 ! mannose metabolic process GO:0006013 9 9 0,000 0,07704116 0,1718668 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,07704116 0,17170027 ! receptor clustering GO:0043113 15 9 0,000 0,07704116 0,17153405 ! epithelial cell development GO:0002064 10 9 0,000 0,07704116 0,17136816 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,07704116 0,17120258 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,07704116 0,17103733 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,07704116 0,1708724 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,07704116 0,17070778 ! motor axon guidance GO:0008045 14 9 0,000 0,07704116 0,17054348 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,07704116 0,17037949 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,07704116 0,17021583 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,07704116 0,17005247 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,07704116 0,16988943 ! blastoderm segmentation GO:0007350 11 9 0,000 0,07704116 0,1697267 ! DNA ligation GO:0006266 14 9 0,000 0,07704116 0,16956428 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,07704116 0,16940217 ! response to amine stimulus GO:0014075 13 9 0,000 0,07704116 0,16924038 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,07704116 0,16907889 ! erythrocyte development GO:0048821 11 9 0,000 0,07704116 0,16891771 ! renal water homeostasis GO:0003091 14 9 0,000 0,07704116 0,16875683 ! postreplication repair GO:0006301 11 9 0,000 0,07704116 0,16859626 ! mRNA cleavage GO:0006379 13 9 0,000 0,07704116 0,168436 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,07704116 0,16827604 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,07704116 0,16811639 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,07704116 0,16795704 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,07704116 0,16779799 ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,07704116 0,16763924 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,07704116 0,16748079 ! acid secretion GO:0046717 14 9 0,000 0,07704116 0,16732264 ! musculoskeletal movement GO:0050881 11 9 0,000 0,07704116 0,16716479 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,07704116 0,16700723 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,07704116 0,16684998 ! purine base metabolic process GO:0006144 18 9 0,000 0,07704116 0,16669301 ! oocyte differentiation GO:0009994 12 9 0,000 0,07704116 0,16653635 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,07704116 0,16637998 ! spleen development GO:0048536 15 9 0,000 0,07704116 0,1662239 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,07704116 0,16606811 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,07704116 0,16591262 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,07704116 0,16575741 ! detection of calcium ion GO:0005513 13 9 0,000 0,07704116 0,1656025 ! blastocyst formation GO:0001825 12 9 0,000 0,07704116 0,16544787 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,07704116 0,16529354 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,07704116 0,16513949 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,07704116 0,16498573 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,07704116 0,16483225 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,07704116 0,16467906 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,07704116 0,16452616 ! prepulse inhibition GO:0060134 14 9 0,000 0,07704116 0,16437354 ! embryonic placenta development GO:0001892 12 9 0,000 0,07704116 0,1642212 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,07704116 0,16406914 ! insulin secretion GO:0030073 17 9 0,000 0,07704116 0,16391737 ! sequestering of metal ion GO:0051238 11 9 0,000 0,07704116 0,16376587 ! response to nicotine GO:0035094 16 9 0,000 0,07704116 0,16361466 ! regulation of synapse organization GO:0050807 12 9 0,000 0,07704116 0,16346372 ! localization within membrane GO:0051668 15 9 0,000 0,07704116 0,16331306 ! regulation of cellular component size GO:0032535 74 52 1,000 0,07768963 0,16453606 ! aging GO:0007568 79 52 1,000 0,07768963 0,16438469 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,07768963 0,1642336 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,08028201 0,16955796 ! kidney development GO:0001822 90 53 1,000 0,08028201 0,1694024 ! glucose catabolic process GO:0006007 66 54 1,000 0,08290104 0,17476846 ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 0,08290104 0,17460841 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,08522857 0,17934649 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,08522857 0,17918256 ! neuron fate specification GO:0048665 11 10 0,000 0,08522857 0,17901892 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,08522857 0,17885558 ! synapsis GO:0007129 13 10 0,000 0,08522857 0,17869254 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,08522857 0,1785298 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,08522857 0,17836735 ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,08522857 0,1782052 ! sulfate transport GO:0008272 12 10 0,000 0,08522857 0,17804334 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,08522857 0,17788178 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,08522857 0,17772051 ! phospholipid efflux GO:0033700 16 10 0,000 0,08522857 0,17755953 ! hippocampus development GO:0021766 19 10 0,000 0,08522857 0,17739884 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,08522857 0,17723844 ! blood vessel remodeling GO:0001974 21 10 0,000 0,08522857 0,17707834 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,08522857 0,17691852 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,08522857 0,17675899 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,08522857 0,17659975 ! pathogenesis GO:0009405 13 10 0,000 0,08522857 0,17644079 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,08522857 0,17628212 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,08522857 0,17612374 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,08522857 0,17596564 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,08522857 0,17580782 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,08522857 0,17565028 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,08522857 0,17549303 ! melanocyte differentiation GO:0030318 15 10 0,000 0,08522857 0,17533606 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,08522857 0,17517937 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,08522857 0,17502296 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,08522857 0,17486683 ! response to X-ray GO:0010165 16 10 0,000 0,08522857 0,17471098 ! B cell proliferation GO:0042100 14 10 0,000 0,08522857 0,1745554 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,08522857 0,1744001 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,08522857 0,17424508 ! forebrain cell migration GO:0021885 17 10 0,000 0,08522857 0,17409034 ! lipid digestion GO:0044241 15 10 0,000 0,08522857 0,17393586 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,08522857 0,17378166 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,08522857 0,17362774 ! UV protection GO:0009650 14 10 0,000 0,08522857 0,17347409 ! entry into host cell GO:0030260 20 10 0,000 0,08522857 0,17332071 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,08522857 0,17316759 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,08522857 0,17301476 ! negative regulation of ossification GO:0030279 19 10 0,000 0,08522857 0,17286218 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,08522857 0,17270988 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,08522857 0,17255785 ! regulation of bone resorption GO:0045124 24 10 0,000 0,08522857 0,17240608 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,08522857 0,17225458 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,08522857 0,17210335 ! regulation of organ growth GO:0046620 11 10 0,000 0,08522857 0,17195238 ! response to dsRNA GO:0043331 18 10 0,000 0,08522857 0,17180168 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,08522857 0,17165124 ! embryonic axis specification GO:0000578 12 10 0,000 0,08522857 0,17150107 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,08522857 0,17135115 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,08522857 0,1712015 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,08522857 0,17105211 ! cranial nerve development GO:0021545 12 10 0,000 0,08522857 0,17090298 ! fucose catabolic process GO:0019317 16 10 0,000 0,08522857 0,17075411 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,08522857 0,1706055 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,08522857 0,17045715 ! protein sumoylation GO:0016925 12 10 0,000 0,08522857 0,17030905 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,08522857 0,17016121 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,08522857 0,17001363 ! zymogen activation GO:0031638 14 10 0,000 0,08522857 0,16986631 ! salivary gland development GO:0007431 22 10 0,000 0,08522857 0,16971924 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,08522857 0,16957242 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,08522857 0,16942586 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,08522857 0,16927955 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,08522857 0,16913349 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,08522857 0,16898769 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,08522857 0,16884213 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,08522857 0,16869683 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,08522857 0,16855178 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,08522857 0,16840697 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,08522857 0,16826242 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,08522857 0,16811811 ! embryonic gut development GO:0048566 11 10 0,000 0,08522857 0,16797405 ! activation of innate immune response GO:0002218 10 10 0,000 0,08522857 0,16783024 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,08522857 0,16768667 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,08522857 0,16754335 ! developmental induction GO:0031128 13 10 0,000 0,08522857 0,16740027 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,08522857 0,16725744 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,08522857 0,16711485 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,08522857 0,1669725 ! water-soluble vitamin metabolic process GO:0006767 71 55 1,000 0,08554606 0,16745186 ! negative regulation of response to stimulus GO:0048585 80 56 1,000 0,08821641 0,17253209 ! multicellular organism reproduction GO:0032504 83 57 1,000 0,09091144 0,17765192 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 1,000 0,09091144 0,17750111 ! coenzyme biosynthetic process GO:0009108 67 57 1,000 0,09091144 0,17735056 ! secondary metabolic process GO:0019748 84 57 1,000 0,09091144 0,17720026 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 0,09091144 0,17705022 ! rRNA transcription GO:0009303 17 11 0,000 0,09334382 0,18163349 ! respiratory burst GO:0045730 14 11 0,000 0,09334382 0,18147995 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,09334382 0,18132667 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,09334382 0,18117366 ! virus-host interaction GO:0019048 17 11 0,000 0,09334382 0,1810209 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,09334382 0,18086839 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,09334382 0,18071615 ! RNA polyadenylation GO:0043631 19 11 0,000 0,09334382 0,18056416 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,09334382 0,18041242 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,09334382 0,18026094 ! mating GO:0007618 14 11 0,000 0,09334382 0,18010972 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,09334382 0,17995874 ! T cell proliferation GO:0042098 20 11 0,000 0,09334382 0,17980803 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,09334382 0,17965756 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,09334382 0,17950734 ! bone resorption GO:0045453 16 11 0,000 0,09334382 0,17935738 ! regulated secretory pathway GO:0045055 14 11 0,000 0,09334382 0,17920766 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,09334382 0,1790582 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,09334382 0,17890899 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,09334382 0,17876002 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,09334382 0,1786113 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,09334382 0,17846283 ! plasma membrane organization GO:0007009 18 11 0,000 0,09334382 0,1783146 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,09334382 0,17816662 ! focal adhesion formation GO:0048041 24 11 0,000 0,09334382 0,17801889 ! mitotic spindle organization GO:0007052 15 11 0,000 0,09334382 0,1778714 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,09334382 0,17772416 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,09334382 0,17757716 ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,09334382 0,1774304 ! adult heart development GO:0007512 11 11 0,000 0,09334382 0,17728388 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,09334382 0,17713761 ! temperature homeostasis GO:0001659 16 11 0,000 0,09334382 0,17699158 ! L-glutamate transport GO:0015813 16 11 0,000 0,09334382 0,17684578 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,09334382 0,17670023 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,09334382 0,17655492 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,09334382 0,17640985 ! stem cell development GO:0048864 29 11 0,000 0,09334382 0,17626501 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,09334382 0,17612041 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,09334382 0,17597605 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,09334382 0,17583193 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,09334382 0,17568804 ! vasoconstriction GO:0042310 15 11 0,000 0,09334382 0,17554438 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,09334382 0,17540097 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,09334382 0,17525778 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,09334382 0,17511483 ! ribosome assembly GO:0042255 13 11 0,000 0,09334382 0,17497211 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,09334382 0,17482963 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,09334382 0,17468737 ! chromatin silencing GO:0006342 19 11 0,000 0,09334382 0,17454535 ! nucleosome positioning GO:0016584 13 11 0,000 0,09334382 0,17440356 ! T cell homeostasis GO:0043029 20 11 0,000 0,09334382 0,174262 ! regulation of isotype switching GO:0045191 19 11 0,000 0,09334382 0,17412067 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,09334382 0,17397956 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,09334382 0,17383869 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,09334382 0,17369804 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,09334382 0,17355763 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,09334382 0,17341743 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,09334382 0,17327747 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,09334382 0,17313773 ! male genitalia development GO:0030539 13 11 0,000 0,09334382 0,17299821 ! cholesterol efflux GO:0033344 19 11 0,000 0,09334382 0,17285892 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,09334382 0,17271986 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,09334382 0,17258101 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,09334382 0,1724424 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,09334382 0,172304 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,09334382 0,17216582 ! defense response to fungus GO:0050832 12 11 0,000 0,09334382 0,17202787 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,09334382 0,17189014 ! lysogeny GO:0030069 18 11 0,000 0,09334382 0,17175263 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,09334382 0,17161533 ! acrosome reaction GO:0007340 13 11 0,000 0,09334382 0,17147826 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,09334382 0,17134141 ! viral reproductive process GO:0022415 87 58 1,000 0,09363051 0,1717306 ! protein maturation by peptide bond cleavage GO:0051605 76 58 1,000 0,09363051 0,17159376 ! lung development GO:0030324 94 59 1,000 0,09637299 0,17647919 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 1,000 0,09913825 0,18139855 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,09913825 0,18125435 ! regulation of heart contraction GO:0008016 91 60 1,000 0,09913825 0,18111039 ! reproductive cellular process GO:0048610 14 12 0,000 0,10138753 0,18507248 ! tRNA modification GO:0006400 14 12 0,000 0,10138753 0,18492571 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,10138753 0,18477918 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,10138753 0,18463288 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,10138753 0,18448681 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,10138753 0,18434097 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,10138753 0,18419536 ! non-recombinational repair GO:0000726 19 12 0,000 0,10138753 0,18404998 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,10138753 0,18390483 ! peroxisomal transport GO:0043574 21 12 0,000 0,10138753 0,18375991 ! cartilage condensation GO:0001502 18 12 0,000 0,10138753 0,18361521 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,10138753 0,18347075 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,10138753 0,18332651 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,10138753 0,1831825 ! heart looping GO:0001947 15 12 0,000 0,10138753 0,18303871 ! palate development GO:0060021 15 12 0,000 0,10138753 0,18289515 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,10138753 0,18275182 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,10138753 0,18260871 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,10138753 0,18246582 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,10138753 0,18232316 ! arginine metabolic process GO:0006525 13 12 0,000 0,10138753 0,18218072 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,10138753 0,1820385 ! methionine metabolic process GO:0006555 13 12 0,000 0,10138753 0,18189651 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,10138753 0,18175473 ! Golgi organization GO:0007030 18 12 0,000 0,10138753 0,18161318 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,10138753 0,18147185 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,10138753 0,18133073 ! monoamine transport GO:0015844 13 12 0,000 0,10138753 0,18118984 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,10138753 0,18104916 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,10138753 0,18090871 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,10138753 0,18076847 ! L-amino acid transport GO:0015807 20 12 0,000 0,10138753 0,18062844 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,10138753 0,18048864 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,10138753 0,18034905 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,10138753 0,18020968 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,10138753 0,18007052 ! cerebellum development GO:0021549 13 12 0,000 0,10138753 0,17993158 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,10138753 0,17979285 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,10138753 0,17965433 ! histone methylation GO:0016571 15 12 0,000 0,10138753 0,17951603 ! autonomic nervous system development GO:0048483 23 12 0,000 0,10138753 0,17937794 ! gland morphogenesis GO:0022612 23 12 0,000 0,10138753 0,17924006 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,10138753 0,1791024 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,10138753 0,17896494 ! response to gamma radiation GO:0010332 20 12 0,000 0,10138753 0,1788277 ! intestinal absorption GO:0050892 19 12 0,000 0,10138753 0,17869067 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,10138753 0,17855385 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,10138753 0,17841723 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,10138753 0,17828083 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,10138753 0,17814463 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,10138753 0,17800864 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,10138753 0,17787286 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,10138753 0,17773729 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,10138753 0,17760192 ! response to cold GO:0009409 14 12 0,000 0,10138753 0,17746676 ! urogenital system development GO:0001655 101 61 1,000 0,10192569 0,17827306 ! negative regulation of ligase activity GO:0051352 91 61 1,000 0,10192569 0,1781376 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! respiratory tube development GO:0030323 99 62 1,000 0,10473469 0,18290796 ! lymphocyte mediated immunity GO:0002449 88 62 1,000 0,10473469 0,18276919 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 0,10473469 0,18263062 ! cAMP-mediated signaling GO:0019933 97 63 1,000 0,10756467 0,18742329 ! viral reproduction GO:0016032 92 63 1,000 0,10756467 0,18728141 ! regulation of lipase activity GO:0060191 109 63 1,000 0,10756467 0,18713974 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,10936034 0,19012001 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,10936034 0,18997642 ! cGMP metabolic process GO:0046068 16 13 0,000 0,10936034 0,18983304 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,10936034 0,18968988 ! water transport GO:0006833 17 13 0,000 0,10936034 0,18954693 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,10936034 0,1894042 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,10936034 0,18926168 ! lipid localization GO:0010876 24 13 0,000 0,10936034 0,18911938 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,10936034 0,18897729 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,10936034 0,18883542 ! organelle fusion GO:0048284 28 13 0,000 0,10936034 0,18869376 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,10936034 0,18855231 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,10936034 0,18841107 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,10936034 0,18827004 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,10936034 0,18812923 ! response to hexose stimulus GO:0009746 19 13 0,000 0,10936034 0,18798862 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,10936034 0,18784823 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,10936034 0,18770804 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,10936034 0,18756807 ! exocrine system development GO:0035272 27 13 0,000 0,10936034 0,1874283 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,10936034 0,18728874 ! bone mineralization GO:0030282 15 13 0,000 0,10936034 0,18714939 ! regulation of exocytosis GO:0017157 17 13 0,000 0,10936034 0,18701024 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,10936034 0,18687131 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,10936034 0,18673257 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,10936034 0,18659405 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,10936034 0,18645573 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,10936034 0,18631761 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,10936034 0,1861797 ! genitalia development GO:0048806 15 13 0,000 0,10936034 0,186042 ! regulation of cellular pH GO:0030641 20 13 0,000 0,10936034 0,18590449 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,10936034 0,18576719 ! cellular pigmentation GO:0033059 24 13 0,000 0,10936034 0,18563009 ! tissue regeneration GO:0042246 21 13 0,000 0,10936034 0,1854932 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,10936034 0,18535651 ! cofactor transport GO:0051181 19 13 0,000 0,10936034 0,18522001 ! NADP metabolic process GO:0006739 18 13 0,000 0,10936034 0,18508372 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,10936034 0,18494763 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,10936034 0,18481174 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,10936034 0,18467605 ! gas transport GO:0015669 18 13 0,000 0,10936034 0,18454056 ! regulation of RNA stability GO:0043487 28 13 0,000 0,10936034 0,18440526 ! heme biosynthetic process GO:0006783 20 13 0,000 0,10936034 0,18427017 ! regulation of axon extension GO:0030516 23 13 0,000 0,10936034 0,18413527 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,10936034 0,18400057 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,10936034 0,18386607 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,10936034 0,18373176 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,10936034 0,18359765 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,10936034 0,18346373 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,10936034 0,18333001 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 0,11041503 0,18496328 ! hexose catabolic process GO:0019320 82 64 1,000 0,11041503 0,18482866 ! respiratory system development GO:0060541 100 64 1,000 0,11041503 0,18469424 ! adaptive immune response GO:0002250 94 64 1,000 0,11041503 0,18456001 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of caspase activity GO:0043281 97 65 1,000 0,11328521 0,18922003 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 0,11328521 0,18908271 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 0,11328521 0,1889456 ! positive regulation of T cell activation GO:0050870 94 65 1,000 0,11328521 0,18880868 ! activation of immune response GO:0002253 83 65 1,000 0,11328521 0,18867196 ! regulation of actin filament-based process GO:0032970 99 66 1,000 0,11617462 0,19334416 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 0,11617462 0,19320436 ! regulation of immune effector process GO:0002697 101 66 1,000 0,11617462 0,19306476 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,11726286 0,19473255 ! superoxide anion generation GO:0042554 18 14 0,000 0,11726286 0,19459205 ! neuron maturation GO:0042551 21 14 0,000 0,11726286 0,19445175 ! regulation of S phase GO:0033261 18 14 0,000 0,11726286 0,19431165 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,11726286 0,19417176 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,11726286 0,19403207 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,11726286 0,19389258 ! inositol metabolic process GO:0006020 20 14 0,000 0,11726286 0,19375329 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,11726286 0,1936142 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,11726286 0,19347531 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,11726286 0,19333661 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,11726286 0,19319812 ! gene silencing by RNA GO:0031047 20 14 0,000 0,11726286 0,19305983 ! response to cAMP GO:0051591 19 14 0,000 0,11726286 0,19292173 ! limbic system development GO:0021761 25 14 0,000 0,11726286 0,19278383 ! startle response GO:0001964 21 14 0,000 0,11726286 0,19264613 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,11726286 0,19250862 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,11726286 0,19237131 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,11726286 0,1922342 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,11726286 0,19209728 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,11726286 0,19196055 ! glycine metabolic process GO:0006544 22 14 0,000 0,11726286 0,19182402 ! pituitary gland development GO:0021983 23 14 0,000 0,11726286 0,19168769 ! cellular response to starvation GO:0009267 21 14 0,000 0,11726286 0,19155155 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,11726286 0,1914156 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,11726286 0,19127984 ! regulation of heart rate GO:0002027 23 14 0,000 0,11726286 0,19114428 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,11726286 0,19100891 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,11726286 0,19087373 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,11726286 0,19073874 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,11726286 0,19060394 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,11726286 0,19046933 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,11726286 0,19033492 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,11726286 0,19020069 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,11726286 0,19006665 ! axon cargo transport GO:0008088 27 14 0,000 0,11726286 0,1899328 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,11726286 0,18979914 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,11726286 0,18966567 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,11726286 0,18953238 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,11726286 0,18939928 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,11726286 0,18926637 ! mRNA splice site selection GO:0006376 26 14 0,000 0,11726286 0,18913364 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,11726286 0,1890011 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,11726286 0,18886875 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,11726286 0,18873658 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,11726286 0,1886046 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,11726286 0,1884728 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,11726286 0,18834118 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,11726286 0,18820975 ! muscle maintenance GO:0046716 19 14 0,000 0,11726286 0,18807851 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,11726286 0,18794744 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,11726286 0,18781656 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,11726286 0,18768586 ! cell killing GO:0001906 20 14 0,000 0,11726286 0,18755534 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,11726286 0,187425 ! cilium assembly GO:0042384 20 14 0,000 0,11726286 0,18729484 ! peptide hormone secretion GO:0030072 23 14 0,000 0,11726286 0,18716487 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 0,11908271 0,18993775 ! acute inflammatory response GO:0002526 92 68 1,000 0,12200893 0,19447023 ! regulation of Ras GTPase activity GO:0032318 110 68 1,000 0,12200893 0,19433555 ! positive regulation of ligase activity GO:0051351 99 69 1,000 0,12495273 0,1988867 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,12509571 0,19897658 ! positive regulation of cell size GO:0045793 20 15 0,000 0,12509571 0,19883907 ! metencephalon development GO:0022037 19 15 0,000 0,12509571 0,19870175 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,12509571 0,19856462 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,12509571 0,19842768 ! skin development GO:0043588 25 15 0,000 0,12509571 0,19829093 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,12509571 0,19815436 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,12509571 0,19801799 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,12509571 0,1978818 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,12509571 0,1977458 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,12509571 0,19760998 ! bile acid metabolic process GO:0008206 22 15 0,000 0,12509571 0,19747436 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,12509571 0,19733891 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,12509571 0,19720366 ! adult walking behavior GO:0007628 25 15 0,000 0,12509571 0,19706859 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,12509571 0,1969337 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,12509571 0,196799 ! myoblast differentiation GO:0045445 27 15 0,000 0,12509571 0,19666448 ! centrosome cycle GO:0007098 16 15 0,000 0,12509571 0,19653015 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,12509571 0,196396 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,12509571 0,19626203 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,12509571 0,19612825 ! cerebral cortex development GO:0021987 29 15 0,000 0,12509571 0,19599464 ! response to osmotic stress GO:0006970 22 15 0,000 0,12509571 0,19586122 ! vesicle coating GO:0006901 25 15 0,000 0,12509571 0,19572798 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,12509571 0,19559493 ! DNA integration GO:0015074 22 15 0,000 0,12509571 0,19546205 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,12509571 0,19532935 ! peptide secretion GO:0002790 27 15 0,000 0,12509571 0,19519684 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,12509571 0,1950645 ! regulation of vasodilation GO:0042312 24 15 0,000 0,12509571 0,19493234 ! neuron recognition GO:0008038 22 15 0,000 0,12509571 0,19480036 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,12509571 0,19466856 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,12509571 0,19453694 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,12509571 0,1944055 ! biomineral formation GO:0031214 18 15 0,000 0,12509571 0,19427423 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,12509571 0,19414314 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,12509571 0,19401223 ! dopamine metabolic process GO:0042417 30 15 0,000 0,12509571 0,19388149 ! organic cation transport GO:0015695 19 15 0,000 0,12509571 0,19375093 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,12509571 0,19362055 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,12509571 0,19349034 ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,12509571 0,19336031 ! defense response to virus GO:0051607 27 15 0,000 0,12509571 0,19323045 ! peptide hormone processing GO:0016486 19 15 0,000 0,12509571 0,19310076 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,12509571 0,19297125 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 1,000 0,12791357 0,1971858 ! humoral immune response GO:0006959 86 70 1,000 0,12791357 0,19705373 ! regulation of catabolic process GO:0009894 106 70 1,000 0,12791357 0,19692183 ! leukocyte mediated immunity GO:0002443 99 71 1,000 0,13089093 0,20137066 ! monosaccharide catabolic process GO:0046365 91 71 1,000 0,13089093 0,20123606 ! protein secretion GO:0009306 27 16 0,000 0,1328595 0,20412616 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,1328595 0,20398989 ! hormone secretion GO:0046879 25 16 0,000 0,1328595 0,20385381 ! bone remodeling GO:0046849 24 16 0,000 0,1328595 0,20371791 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,1328595 0,20358218 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,1328595 0,20344664 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,1328595 0,20331128 ! glial cell development GO:0021782 24 16 0,000 0,1328595 0,2031761 ! patterning of blood vessels GO:0001569 24 16 0,000 0,1328595 0,2030411 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,1328595 0,20290628 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,1328595 0,20277164 ! protein polyubiquitination GO:0000209 26 16 0,000 0,1328595 0,20263717 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,1328595 0,20250289 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,1328595 0,20236878 GO:0030968|endoplasmic reticulum unfolded protein response, ! fructose metabolic process GO:0006000 20 16 0,000 0,1328595 0,20223485 ! regulation of protein binding GO:0043393 27 16 0,000 0,1328595 0,2021011 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,1328595 0,20196752 ! protein export from nucleus GO:0006611 24 16 0,000 0,1328595 0,20183412 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,1328595 0,2017009 ! DNA replication initiation GO:0006270 25 16 0,000 0,1328595 0,20156785 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,1328595 0,20143498 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,1328595 0,20130228 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,1328595 0,20116976 ! diencephalon development GO:0021536 25 16 0,000 0,1328595 0,20103741 ! oogenesis GO:0048477 23 16 0,000 0,1328595 0,20090523 ! neural crest cell migration GO:0001755 24 16 0,000 0,1328595 0,20077323 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,1328595 0,2006414 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,1328595 0,20050975 GO:0006626|protein targeting to mitochondrion, ! steroid catabolic process GO:0006706 22 16 0,000 0,1328595 0,20037827 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,1328595 0,20024696 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,1328595 0,20011582 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,1328595 0,19998486 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,1328595 0,19985406 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,1328595 0,19972344 ! sperm-egg recognition GO:0035036 16 16 0,000 0,1328595 0,19959298 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,1328595 0,1994627 ! nerve development GO:0021675 18 16 0,000 0,1328595 0,19933259 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,1328595 0,19920265 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,1328595 0,19907287 ! negative regulation of translation GO:0017148 22 16 0,000 0,1328595 0,19894327 ! regulation of peptidase activity GO:0052547 106 72 1,000 0,13388429 0,20034734 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,13388429 0,20021708 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 1,000 0,13388429 0,20008698 ! mitochondrion organization GO:0007005 104 73 1,000 0,13689313 0,20445078 ! response to oxygen levels GO:0070482 137 74 1,000 0,13991695 0,20883127 ! protein import into nucleus GO:0006606 118 74 1,000 0,13991695 0,20869584 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 0,13991695 0,20856058 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,14055484 0,20937574 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,14055484 0,20924022 ! negative regulation of defense response GO:0031348 19 17 0,000 0,14055484 0,20910488 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,14055484 0,20896971 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,14055484 0,20883471 ! glycerol metabolic process GO:0006071 20 17 0,000 0,14055484 0,20869989 ! zinc ion transport GO:0006829 20 17 0,000 0,14055484 0,20856525 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,14055484 0,20843078 ! signal complex assembly GO:0007172 29 17 0,000 0,14055484 0,20829648 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,14055484 0,20816235 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,14055484 0,2080284 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,14055484 0,20789462 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,14055484 0,20776101 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,14055484 0,20762758 ! memory GO:0007613 25 17 0,000 0,14055484 0,20749431 ! keratinization GO:0031424 17 17 0,000 0,14055484 0,20736122 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,14055484 0,20722829 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,14055484 0,20709554 ! retinoid metabolic process GO:0001523 22 17 0,000 0,14055484 0,20696296 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,14055484 0,20683054 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,14055484 0,2066983 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,14055484 0,20656622 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,14055484 0,20643431 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,14055484 0,20630258 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,14055484 0,20617101 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,14055484 0,2060396 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,14055484 0,20590837 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,14055484 0,2057773 ! membrane budding GO:0006900 29 17 0,000 0,14055484 0,2056464 ! heme metabolic process GO:0042168 27 17 0,000 0,14055484 0,20551566 ! actin filament bundle formation GO:0051017 26 17 0,000 0,14055484 0,20538509 ! neuromuscular junction development GO:0007528 23 17 0,000 0,14055484 0,20525469 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,14055484 0,20512445 ! body fluid secretion GO:0007589 27 17 0,000 0,14055484 0,20499438 ! stem cell differentiation GO:0048863 36 17 0,000 0,14055484 0,20486447 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,14055484 0,20473473 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,14055484 0,20460515 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,14055484 0,20447573 ! sensory perception of pain GO:0019233 23 17 0,000 0,14055484 0,20434648 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,14055484 0,2042174 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,14055484 0,20408847 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,14055484 0,20395971 ! synaptogenesis GO:0007416 24 17 0,000 0,14055484 0,20383111 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,14055484 0,20370267 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,14055484 0,20357439 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,14055484 0,20344628 ! cell-cell junction organization GO:0045216 25 17 0,000 0,14055484 0,20331833 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,14055484 0,20319053 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,14055484 0,2030629 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,14055484 0,20293543 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,14055484 0,20280812 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,14055484 0,20268096 ! response to nutrient GO:0007584 104 75 1,000 0,14295525 0,2060132 ! nuclear import GO:0051170 121 75 1,000 0,14295525 0,2058842 ! amine biosynthetic process GO:0009309 97 76 1,000 0,14600754 0,21014853 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,14818233 0,21314531 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,14818233 0,21301209 ! positive regulation of translation GO:0045727 28 18 0,000 0,14818233 0,21287904 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,14818233 0,21274616 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,14818233 0,21261344 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,14818233 0,21248089 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,14818233 0,2123485 ! cAMP metabolic process GO:0046058 33 18 0,000 0,14818233 0,21221628 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,14818233 0,21208422 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,14818233 0,21195233 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,14818233 0,2118206 ! axis specification GO:0009798 26 18 0,000 0,14818233 0,21168904 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,14818233 0,21155763 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,14818233 0,2114264 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,14818233 0,21129532 ! glutamine metabolic process GO:0006541 23 18 0,000 0,14818233 0,2111644 ! response to retinoic acid GO:0032526 25 18 0,000 0,14818233 0,21103365 ! pigmentation during development GO:0048066 31 18 0,000 0,14818233 0,21090306 ! central nervous system neuron development GO:0021954 30 18 0,000 0,14818233 0,21077263 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,14818233 0,21064237 ! fucose metabolic process GO:0006004 26 18 0,000 0,14818233 0,21051226 ! response to fungus GO:0009620 19 18 0,000 0,14818233 0,21038231 ! peptide cross-linking GO:0018149 31 18 0,000 0,14818233 0,21025253 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,14818233 0,2101229 ! heart process GO:0003015 27 18 0,000 0,14818233 0,20999344 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,14818233 0,20986413 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,14818233 0,20973498 ! visual learning GO:0008542 35 18 0,000 0,14818233 0,209606 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,14818233 0,20947717 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,14818233 0,20934849 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,14818233 0,20921998 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,14818233 0,20909163 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,14818233 0,20896343 ! vitamin transport GO:0051180 24 18 0,000 0,14818233 0,20883539 ! hormone transport GO:0009914 27 18 0,000 0,14818233 0,2087075 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,14818233 0,20857977 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,14818233 0,2084522 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,14818233 0,20832479 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,14818233 0,20819753 ! cell-cell recognition GO:0009988 20 18 0,000 0,14818233 0,20807042 ! regulation of glucose import GO:0046324 21 18 0,000 0,14818233 0,20794347 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,14818233 0,20781668 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,14818233 0,20769004 ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 0,14907334 0,20881163 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,15215218 0,21299453 ! regulation of cyclase activity GO:0031279 132 78 1,000 0,15215218 0,21286497 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 0,15524358 0,2170579 ! regulation of lyase activity GO:0051339 133 79 1,000 0,15524358 0,21692603 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,15574255 0,21749111 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,15574255 0,21735914 ! positive regulation of ossification GO:0045778 30 19 0,000 0,15574255 0,21722733 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,15574255 0,21709567 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,15574255 0,21696418 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,15574255 0,21683285 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,15574255 0,21670167 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,15574255 0,21657065 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,15574255 0,2164398 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,15574255 0,2163091 ! regeneration GO:0031099 32 19 0,000 0,15574255 0,21617855 ! response to alkaloid GO:0043279 32 19 0,000 0,15574255 0,21604817 ! sensory perception of taste GO:0050909 23 19 0,000 0,15574255 0,21591794 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,15574255 0,21578787 ! smooth muscle contraction GO:0006939 36 19 0,000 0,15574255 0,21565795 ! peroxisome organization GO:0007031 29 19 0,000 0,15574255 0,2155282 ! digestive system process GO:0022600 30 19 0,000 0,15574255 0,21539859 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,15574255 0,21526915 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,15574255 0,21513986 ! response to vitamin A GO:0033189 26 19 0,000 0,15574255 0,21501072 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,15574255 0,21488174 ! response to starvation GO:0042594 30 19 0,000 0,15574255 0,21475292 ! sex determination GO:0007530 29 19 0,000 0,15574255 0,21462424 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,15574255 0,21449573 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,15574255 0,21436736 ! cytolysis GO:0019835 20 19 0,000 0,15574255 0,21423915 ! renal system process GO:0003014 35 19 0,000 0,15574255 0,2141111 ! vasodilation GO:0042311 33 19 0,000 0,15574255 0,21398319 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,15574255 0,21385544 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,15574255 0,21372784 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,15574255 0,2136004 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,15574255 0,2134731 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,15574255 0,21334596 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,15574255 0,21321897 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,15574255 0,21309213 ! sarcomere organization GO:0045214 23 19 0,000 0,15574255 0,21296544 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,15574255 0,2128389 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,15574255 0,21271251 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,15574255 0,21258627 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,15574255 0,21246018 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,15574255 0,21233424 ! protein stabilization GO:0050821 26 19 0,000 0,15574255 0,21220845 ! chromatin assembly GO:0031497 102 80 1,000 0,15834709 0,21562955 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 1,000 0,15834709 0,21550196 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 0,15834709 0,21537452 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 1,000 0,15834709 0,21524723 ! forebrain development GO:0030900 131 80 1,000 0,15834709 0,21512009 ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 0,16146226 0,21922266 ! vitamin metabolic process GO:0006766 103 81 1,000 0,16146226 0,21909333 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,1632361 0,22136971 ! iron ion transport GO:0006826 37 20 0,000 0,1632361 0,22123927 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,1632361 0,22110897 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,1632361 0,22097883 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,1632361 0,22084884 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,1632361 0,22071901 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,1632361 0,22058933 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,1632361 0,2204598 ! spinal cord development GO:0021510 31 20 0,000 0,1632361 0,22033042 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,1632361 0,22020119 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,1632361 0,22007212 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,1632361 0,21994319 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,1632361 0,21981442 ! chromosome condensation GO:0030261 31 20 0,000 0,1632361 0,2196858 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,1632361 0,21955733 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,1632361 0,21942901 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,1632361 0,21930084 ! pallium development GO:0021543 38 20 0,000 0,1632361 0,21917282 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,1632361 0,21904494 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,1632361 0,21891722 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,1632361 0,21878965 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,1632361 0,21866222 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,1632361 0,21853494 ! collagen catabolic process GO:0030574 25 20 0,000 0,1632361 0,21840781 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,1632361 0,21828083 ! alditol metabolic process GO:0019400 24 20 0,000 0,1632361 0,218154 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,16772577 0,22402396 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 1,000 0,16772577 0,22389394 ! regulation of cell adhesion GO:0030155 159 83 1,000 0,16772577 0,22376407 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,17066357 0,22755142 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,17066357 0,22741959 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,17066357 0,2272879 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,17066357 0,22715637 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,17066357 0,22702499 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,17066357 0,22689376 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,17066357 0,22676268 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,17066357 0,22663176 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,17066357 0,22650098 ! vesicle docking GO:0048278 27 21 0,000 0,17066357 0,22637036 ! phototransduction GO:0007602 25 21 0,000 0,17066357 0,22623989 ! dendrite development GO:0016358 35 21 0,000 0,17066357 0,22610956 ! visual behavior GO:0007632 39 21 0,000 0,17066357 0,22597939 ! ovarian follicle development GO:0001541 30 21 0,000 0,17066357 0,22584937 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,17066357 0,2257195 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,17066357 0,22558977 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,17066357 0,2254602 ! cell aging GO:0007569 32 21 0,000 0,17066357 0,22533077 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,17066357 0,22520149 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,17066357 0,22507236 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,17066357 0,22494338 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,17066357 0,22481455 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,17066357 0,22468586 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,17066357 0,22455732 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,17066357 0,22442893 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,17066357 0,22430069 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,17066357 0,22417259 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,17066357 0,22404464 ! immunoglobulin production GO:0002377 33 21 0,000 0,17066357 0,22391683 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,17066357 0,22378917 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,17066357 0,22366165 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,17066357 0,22353428 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,17066357 0,22340706 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,17066357 0,22327998 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,17066357 0,22315304 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,17066357 0,22302625 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,17066357 0,2228996 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,17066357 0,2227731 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,17066357 0,22264674 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,17066357 0,22252052 ! protein-DNA complex assembly GO:0065004 107 84 1,000 0,17087324 0,22266768 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 0,17403062 0,22665369 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,17403062 0,22652542 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,17719749 0,2305171 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,17802552 0,23146337 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,17802552 0,2313326 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,17802552 0,23120198 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,17802552 0,23107151 ! leukocyte adhesion GO:0007159 38 22 0,000 0,17802552 0,23094118 ! molting cycle process GO:0022404 40 22 0,000 0,17802552 0,230811 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! glutamate signaling pathway GO:0007215 34 22 0,000 0,17802552 0,23068096 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,17802552 0,23055107 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,17802552 0,23042133 ! vasculogenesis GO:0001570 33 22 0,000 0,17802552 0,23029174 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,17802552 0,23016229 GO:0051297|centrosome organization, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,17802552 0,23003298 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,17802552 0,22990382 ! lysosome organization GO:0007040 37 22 0,000 0,17802552 0,22977481 ! ureteric bud development GO:0001657 32 22 0,000 0,17802552 0,22964594 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,17802552 0,22951721 ! regulation of behavior GO:0050795 38 22 0,000 0,17802552 0,22938863 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,17802552 0,22926019 ! membrane depolarization GO:0051899 35 22 0,000 0,17802552 0,2291319 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,17802552 0,22900375 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,17802552 0,22887574 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,17802552 0,22874788 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,17802552 0,22862016 ! blastocyst development GO:0001824 37 22 0,000 0,17802552 0,22849258 ! neural tube closure GO:0001843 33 22 0,000 0,17802552 0,22836515 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,17802552 0,22823785 ! protein tetramerization GO:0051262 39 22 0,000 0,17802552 0,2281107 ! nucleosome organization GO:0034728 114 87 1,000 0,18037344 0,23099048 ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,18037344 0,23086194 ! protein processing GO:0016485 114 88 1,000 0,18355805 0,2348073 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,18532255 0,23693266 ! neuron fate commitment GO:0048663 32 23 0,000 0,18532255 0,23680103 ! embryonic pattern specification GO:0009880 31 23 0,000 0,18532255 0,23666955 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,18532255 0,23653821 ! myelination GO:0042552 35 23 0,000 0,18532255 0,23640702 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,18532255 0,23627598 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,18532255 0,23614508 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,18532255 0,23601432 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,18532255 0,23588371 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,18532255 0,23575324 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,18532255 0,23562292 ! vesicle targeting GO:0006903 32 23 0,000 0,18532255 0,23549274 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,18532255 0,23536271 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,18532255 0,23523282 ! osteoblast differentiation GO:0001649 40 23 0,000 0,18532255 0,23510307 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,18532255 0,23497346 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,18532255 0,234844 ! interaction with host GO:0051701 37 23 0,000 0,18532255 0,23471468 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,18532255 0,23458551 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,18532255 0,23445647 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,18532255 0,23432758 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,18532255 0,23419883 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,18532255 0,23407022 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,18532255 0,23394175 ! cell fate determination GO:0001709 45 23 0,000 0,18532255 0,23381342 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,18532255 0,23368523 ! spermatid development GO:0007286 33 23 0,000 0,18532255 0,23355719 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,18532255 0,23342928 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,18532255 0,23330151 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,18532255 0,23317389 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,18532255 0,2330464 ! telomere organization GO:0032200 32 23 0,000 0,18532255 0,23291905 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,18532255 0,23279184 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,18532255 0,23266477 ! regulation of amine transport GO:0051952 38 23 0,000 0,18532255 0,23253784 ! liver development GO:0001889 40 23 0,000 0,18532255 0,23241105 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,18675094 0,23407475 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,19255521 0,2412184 ! initiation of viral infection GO:0019059 42 24 0,000 0,19255521 0,24108709 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,19255521 0,24095592 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,19255521 0,24082489 ! superoxide metabolic process GO:0006801 32 24 0,000 0,19255521 0,24069401 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,19255521 0,24056327 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,19255521 0,24043267 ! fat cell differentiation GO:0045444 37 24 0,000 0,19255521 0,24030221 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,19255521 0,2401719 ! sperm motility GO:0030317 27 24 0,000 0,19255521 0,24004172 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,19255521 0,23991169 ! vacuole organization GO:0007033 39 24 0,000 0,19255521 0,2397818 ! receptor metabolic process GO:0043112 37 24 0,000 0,19255521 0,23965205 ! neural crest cell development GO:0014032 39 24 0,000 0,19255521 0,23952243 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,19255521 0,23939296 ! primary neural tube formation GO:0014020 35 24 0,000 0,19255521 0,23926363 ! negative regulation of cell development GO:0010721 56 24 0,000 0,19255521 0,23913444 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,19255521 0,23900539 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,19255521 0,23887647 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,19255521 0,2387477 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,19255521 0,23861906 ! glutathione metabolic process GO:0006749 29 24 0,000 0,19255521 0,23849057 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,19255521 0,23836221 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,19255521 0,23823399 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,19255521 0,2381059 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 1,000 0,19637532 0,24269922 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,19637532 0,24256887 ! positive regulation of immune response GO:0050778 121 92 1,000 0,19637532 0,24243867 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,19959742 0,24628437 ! peptidyl-amino acid modification GO:0018193 147 93 1,000 0,19959742 0,24615231 ! carbohydrate catabolic process GO:0016052 121 93 1,000 0,19959742 0,2460204 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,19972407 0,24604465 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,19972407 0,24591293 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,19972407 0,24578136 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,19972407 0,24564992 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,19972407 0,24551863 ! peptide transport GO:0015833 43 25 0,000 0,19972407 0,24538748 ! male gonad development GO:0008584 33 25 0,000 0,19972407 0,24525646 ! iron ion homeostasis GO:0055072 39 25 0,000 0,19972407 0,24512559 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,19972407 0,24499486 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,19972407 0,24486426 ! phospholipid transport GO:0015914 35 25 0,000 0,19972407 0,24473381 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,19972407 0,24460349 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,19972407 0,24447331 ! detection of light stimulus GO:0009583 30 25 0,000 0,19972407 0,24434327 ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,19972407 0,24421337 ! leukocyte proliferation GO:0070661 39 25 0,000 0,19972407 0,24408361 GO:0032943|mononuclear cell proliferation, ! electron transport chain GO:0022900 123 94 1,000 0,20282588 0,24774271 ! response to oxidative stress GO:0006979 141 94 1,000 0,20282588 0,24761121 ! angiogenesis GO:0001525 149 95 1,000 0,20606034 0,25142641 ! carboxylic acid transport GO:0046942 147 95 1,000 0,20606034 0,2512931 GO:0015849|organic acid transport, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,20682969 0,25209766 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,20682969 0,25196413 ! translational initiation GO:0006413 43 26 0,000 0,20682969 0,25183074 ! regulation of pH GO:0006885 36 26 0,000 0,20682969 0,2516975 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,20682969 0,2515644 ! circadian rhythm GO:0007623 42 26 0,000 0,20682969 0,25143144 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,20682969 0,25129861 ! post-embryonic development GO:0009791 42 26 0,000 0,20682969 0,25116593 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,20682969 0,25103339 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,20682969 0,25090099 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,20682969 0,25076873 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,20682969 0,25063661 ! spermatid differentiation GO:0048515 36 26 0,000 0,20682969 0,25050462 ! regulation of coagulation GO:0050818 39 26 0,000 0,20682969 0,25037278 ! in utero embryonic development GO:0001701 147 96 1,000 0,20930045 0,25323042 ! protein maturation GO:0051604 129 96 1,000 0,20930045 0,25309728 ! response to light stimulus GO:0009416 153 96 1,000 0,20930045 0,25296428 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,21254585 0,25675181 ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,21387262 0,25821891 ! membrane docking GO:0022406 39 27 0,000 0,21387262 0,25808343 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,21387262 0,2579481 ! catechol metabolic process GO:0009712 43 27 0,000 0,21387262 0,2578129 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,21387262 0,25767785 ! acute-phase response GO:0006953 42 27 0,000 0,21387262 0,25754294 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,21387262 0,25740817 ! myofibril assembly GO:0030239 36 27 0,000 0,21387262 0,25727354 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,21387262 0,25713906 ! response to ionizing radiation GO:0010212 47 27 0,000 0,21387262 0,25700471 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,21387262 0,25687051 ! natural killer cell activation GO:0030101 35 27 0,000 0,21387262 0,25673644 ! lipid oxidation GO:0034440 38 27 0,000 0,21387262 0,25660251 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,21387262 0,25646873 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,21387262 0,25633508 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,21387262 0,25620157 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,21387262 0,2560682 ! gene silencing GO:0016458 41 27 0,000 0,21387262 0,25593497 ! protein import GO:0017038 156 99 1,000 0,21905115 0,26199565 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,22085341 0,26401395 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,22085341 0,2638768 ! phenol metabolic process GO:0018958 44 28 0,000 0,22085341 0,26373979 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,22085341 0,26360293 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,22085341 0,2634662 ! cell junction assembly GO:0034329 56 28 0,000 0,22085341 0,26332962 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,22085341 0,26319318 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,22085341 0,26305688 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,22085341 0,26292073 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,22085341 0,26278471 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,22085341 0,26264883 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,22085341 0,2625131 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,22085341 0,2623775 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,22085341 0,26224205 ! mesoderm formation GO:0001707 46 28 0,000 0,22085341 0,26210673 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,22085341 0,26197155 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,22085341 0,26183652 ! ensheathment of neurons GO:0007272 43 28 0,000 0,22085341 0,26170162 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,22085341 0,26156686 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,22085341 0,26143224 ! neural tube formation GO:0001841 41 28 0,000 0,22085341 0,26129776 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,22085341 0,26116341 ! placenta development GO:0001890 37 28 0,000 0,22085341 0,26102921 ! regulation of translation GO:0006417 151 100 1,000 0,22231037 0,26261626 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 1,000 0,22231037 0,26248145 ! protein localization in organelle GO:0033365 161 100 1,000 0,22231037 0,26234677 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,22777261 0,26865487 ! regulation of innate immune response GO:0045088 38 29 0,000 0,22777261 0,26851717 ! ovulation cycle process GO:0022602 41 29 0,000 0,22777261 0,26837961 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,22777261 0,26824219 ! protein targeting to membrane GO:0006612 53 29 0,000 0,22777261 0,26810491 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,22777261 0,26796778 ! mismatch repair GO:0006298 34 29 0,000 0,22777261 0,26783078 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,22777261 0,26769392 ! muscle cell development GO:0055001 38 29 0,000 0,22777261 0,2675572 ! formation of primary germ layer GO:0001704 48 29 0,000 0,22777261 0,26742062 ! telencephalon development GO:0021537 52 29 0,000 0,22777261 0,26728418 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,22777261 0,26714788 ! eye morphogenesis GO:0048592 51 29 0,000 0,22777261 0,26701172 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,22777261 0,2668757 ! tissue homeostasis GO:0001894 42 29 0,000 0,22777261 0,26673982 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,23463076 0,27463142 ! collagen metabolic process GO:0032963 40 30 0,000 0,23463076 0,27449173 ! organic anion transport GO:0015711 51 30 0,000 0,23463076 0,27435218 ! cholesterol transport GO:0030301 46 30 0,000 0,23463076 0,27421278 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,23463076 0,27407351 ! spliceosome assembly GO:0000245 49 30 0,000 0,23463076 0,27393439 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,23463076 0,2737954 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,23463076 0,27365656 ! ceramide metabolic process GO:0006672 43 30 0,000 0,23463076 0,27351786 ! ovulation cycle GO:0042698 43 30 0,000 0,23463076 0,2733793 ! hindbrain development GO:0030902 45 30 0,000 0,23463076 0,27324088 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,23463076 0,2731026 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,23463076 0,27296446 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,23463076 0,27282646 ! response to heat GO:0009408 41 30 0,000 0,23463076 0,2726886 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,23463076 0,27255088 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,23463076 0,2724133 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,24142839 0,28016412 ! negative regulation of secretion GO:0051048 49 31 0,000 0,24142839 0,28002284 ! glial cell differentiation GO:0010001 55 31 0,000 0,24142839 0,2798817 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,24142839 0,2797407 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,24142839 0,27959984 ! odontogenesis GO:0042476 50 31 0,000 0,24142839 0,27945913 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,24142839 0,27931856 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,24142839 0,27917812 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,24142839 0,27903783 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,24142839 0,27889768 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,24142839 0,27875768 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,24142839 0,27861781 ! cell fate specification GO:0001708 37 31 0,000 0,24142839 0,27847808 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,24142839 0,27833849 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,24142839 0,27819904 ! RNA modification GO:0009451 40 31 0,000 0,24142839 0,27805973 ! regulation of muscle development GO:0048634 48 32 0,000 0,24816603 0,28567661 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,24816603 0,2855337 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,24816603 0,28539093 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,24816603 0,28524831 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,24816603 0,28510583 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,24816603 0,28496349 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,24816603 0,28482129 ! peripheral nervous system development GO:0007422 53 32 0,000 0,24816603 0,28467924 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,24816603 0,28453732 ! cytokine production GO:0001816 44 32 0,000 0,24816603 0,28439555 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,24816603 0,28425392 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,24816603 0,28411243 ! vesicle localization GO:0051648 47 32 0,000 0,24816603 0,28397108 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,25484421 0,29146777 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,25484421 0,2913229 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,25484421 0,29117818 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,25484421 0,29103361 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,25484421 0,29088917 ! ear morphogenesis GO:0042471 42 33 0,000 0,25484421 0,29074488 ! actomyosin structure organization GO:0031032 43 33 0,000 0,25484421 0,29060074 ! cell junction organization GO:0034330 63 33 0,000 0,25484421 0,29045673 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,25484421 0,29031287 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,25484421 0,29016915 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,25484421 0,29002557 GO:0042593|glucose homeostasis, ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,25484421 0,28988214 ! female gonad development GO:0008585 49 33 0,000 0,25484421 0,28973885 ! positive regulation of cell development GO:0010720 54 33 0,000 0,25484421 0,28959569 ! lipid homeostasis GO:0055088 55 33 0,000 0,25484421 0,28945268 ! regulation of proteolysis GO:0030162 50 33 0,000 0,25484421 0,28930981 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,25484421 0,28916709 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,26146345 0,29653153 ! mRNA catabolic process GO:0006402 48 34 0,000 0,26146345 0,29638538 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,26146345 0,29623938 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,26146345 0,29609352 ! feeding behavior GO:0007631 45 34 0,000 0,26146345 0,29594781 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,26146345 0,29580223 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,26146345 0,2956568 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,26146345 0,29551152 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,26146345 0,29536638 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,26146345 0,29522137 ! female gamete generation GO:0007292 43 34 0,000 0,26146345 0,29507652 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,26146345 0,2949318 ! polyol metabolic process GO:0019751 44 34 0,000 0,26146345 0,29478723 ! aerobic respiration GO:0009060 47 34 0,000 0,26146345 0,29464279 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,26146345 0,2944985 ! embryonic organ development GO:0048568 45 34 0,000 0,26146345 0,29435435 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,26146345 0,29421034 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,26802427 0,30144539 ! Notch signaling pathway GO:0007219 56 35 0,000 0,26802427 0,30129806 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,26802427 0,30115087 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,26802427 0,30100382 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,26802427 0,30085692 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,26802427 0,30071016 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,26802427 0,30056354 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,26802427 0,30041707 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,26802427 0,30027074 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,26802427 0,30012455 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,26802427 0,2999785 ! glycogen metabolic process GO:0005977 48 35 0,000 0,26802427 0,2998326 ! pigment metabolic process GO:0042440 61 35 0,000 0,26802427 0,29968684 ! protein homooligomerization GO:0051260 52 35 0,000 0,26802427 0,29954122 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,27452718 0,30665979 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,27452718 0,30651093 ! organic ether metabolic process GO:0018904 46 36 0,000 0,27452718 0,30636221 ! tissue remodeling GO:0048771 62 36 0,000 0,27452718 0,30621363 ! neural tube development GO:0021915 50 36 0,000 0,27452718 0,3060652 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,27452718 0,30591691 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,27452718 0,30576877 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,27452718 0,30562077 ! glucan metabolic process GO:0044042 49 36 0,000 0,27452718 0,30547291 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,28097268 0,3124938 ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,28097268 0,31234276 ! learning GO:0007612 67 37 0,000 0,28097268 0,31219187 ! ion transmembrane transport GO:0034220 56 37 0,000 0,28097268 0,31204113 ! regulation of protein secretion GO:0050708 51 37 0,000 0,28097268 0,31189053 ! amino acid activation GO:0043038 52 37 0,000 0,28097268 0,31174007 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,28736129 0,31867453 ! gliogenesis GO:0042063 71 38 0,000 0,28736129 0,31852095 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,28736129 0,31836752 ! phagocytosis GO:0006909 60 38 0,000 0,28736129 0,31821424 ! maintenance of location in cell GO:0051651 69 38 0,000 0,28736129 0,3180611 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,2936935 0,32491344 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,2936935 0,32475723 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,2936935 0,32460117 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,2936935 0,32444527 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,2936935 0,32428951 ! male sex differentiation GO:0046661 53 39 0,000 0,2936935 0,3241339 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,2936935 0,32397844 ! JNK cascade GO:0007254 54 39 0,000 0,2936935 0,32382313 ! developmental growth GO:0048589 62 39 0,000 0,2936935 0,32366796 ! synapse organization GO:0050808 55 39 0,000 0,2936935 0,32351295 ! response to calcium ion GO:0051592 58 40 0,000 0,2999698 0,33026833 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,2999698 0,3301103 ! regulation of tube size GO:0035150 60 40 0,000 0,2999698 0,32995243 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,2999698 0,32979471 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,2999698 0,32963714 ! peptide metabolic process GO:0006518 56 40 0,000 0,2999698 0,32947972 ! inner ear development GO:0048839 57 40 0,000 0,2999698 0,32932245 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,2999698 0,32916533 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 53 40 0,000 0,2999698 0,32900836 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,2999698 0,32885154 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,2999698 0,32869487 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,30619068 0,3353517 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,30619068 0,33519208 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,30619068 0,33503262 ! glucose transport GO:0015758 52 41 0,000 0,30619068 0,33487331 ! endosome transport GO:0016197 71 41 0,000 0,30619068 0,33471415 ! striated muscle contraction GO:0006941 62 41 0,000 0,30619068 0,33455514 ! biopolymer methylation GO:0043414 62 41 0,000 0,30619068 0,33439628 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,30619068 0,33423757 ! mitochondrial transport GO:0006839 60 42 0,000 0,31235664 0,34080658 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,31235664 0,34064498 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,31235664 0,34048354 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,31235664 0,34032225 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,31235664 0,34016111 ! hexose transport GO:0008645 54 42 0,000 0,31235664 0,34000013 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,31235664 0,33983929 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,31235664 0,33967861 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,31235664 0,33951809 ! excretion GO:0007588 63 42 0,000 0,31235664 0,33935771 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,31235664 0,33919748 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,31235664 0,33903741 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,31235664 0,33887749 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,31846815 0,345345 ! neuromuscular process GO:0050905 79 43 0,000 0,31846815 0,34518225 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,31846815 0,34501966 ! tRNA processing GO:0008033 49 43 0,000 0,31846815 0,34485722 ! vesicle organization GO:0016050 79 43 0,000 0,31846815 0,34469494 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,31846815 0,3445328 ! methylation GO:0032259 64 43 0,000 0,31846815 0,34437082 ! regulation of action potential GO:0001508 71 44 0,000 0,32452569 0,35075615 ! regulation of ion transport GO:0043269 57 44 0,000 0,32452569 0,3505914 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,32452569 0,3504268 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,32452569 0,35026236 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,32452569 0,35009807 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,32452569 0,34993393 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,32452569 0,34976995 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,32452569 0,34960613 ! RNA catabolic process GO:0006401 64 45 0,000 0,33052973 0,35590748 ! positive regulation of defense response GO:0031349 59 45 0,000 0,33052973 0,35574094 ! regulation of translational initiation GO:0006446 64 45 0,000 0,33052973 0,35557455 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,33052973 0,35540831 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,33052973 0,35524223 ! cell recognition GO:0008037 58 45 0,000 0,33052973 0,35507631 ! cell maturation GO:0048469 60 45 0,000 0,33052973 0,35491054 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,33648075 0,36113193 ! regulation of ossification GO:0030278 71 46 0,000 0,33648075 0,36096349 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,34237921 0,36711989 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,34237921 0,36694882 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,34237921 0,36677791 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,34237921 0,36660716 ! chloride transport GO:0006821 67 48 0,000 0,34822556 0,37269371 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,34822556 0,37252037 ! response to temperature stimulus GO:0009266 62 48 0,000 0,34822556 0,37234718 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,34822556 0,37217416 ! gastrulation GO:0007369 73 48 0,000 0,34822556 0,3720013 ! heart morphogenesis GO:0003007 65 48 0,000 0,34822556 0,37182859 ! regulation of DNA replication GO:0006275 75 48 0,000 0,34822556 0,37165605 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,34822556 0,37148367 ! regulation of endocytosis GO:0030100 63 48 0,000 0,34822556 0,37131145 ! nuclear export GO:0051168 69 48 0,000 0,34822556 0,37113938 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,34822556 0,37096748 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,35402028 0,37696603 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,35402028 0,37679159 ! sensory perception of smell GO:0007608 61 49 0,000 0,35402028 0,37661731 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,35402028 0,3764432 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,35402028 0,37626924 ! RNA elongation GO:0006354 62 49 0,000 0,35402028 0,37609544 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,35402028 0,37592181 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,35402028 0,37574833 ! germ cell development GO:0007281 68 49 0,000 0,35402028 0,37557502 ! cartilage development GO:0051216 70 49 0,000 0,35402028 0,37540186 ! maintenance of location GO:0051235 84 49 0,000 0,35402028 0,37522886 ! ear development GO:0043583 72 50 0,000 0,3597638 0,38114083 ! proton transport GO:0015992 75 50 0,000 0,3597638 0,38096535 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,3597638 0,38079003 ! positive regulation of secretion GO:0051047 71 51 0,000 0,36545658 0,3866376 ! hydrogen transport GO:0006818 77 51 0,000 0,36545658 0,38645984 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,36545658 0,38628223 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of cell migration GO:0030335 92 51 0,000 0,36545658 0,3861048 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,36545658 0,38592752 ! transition metal ion transport GO:0000041 74 52 0,000 0,37109907 0,39170623 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,37109907 0,39152654 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,37109907 0,39134703 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,37669171 0,39706275 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,37669171 0,39688087 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,37669171 0,39669914 ! single fertilization GO:0007338 59 53 0,000 0,37669171 0,39651759 ! amino acid transport GO:0006865 84 54 0,000 0,38223493 0,4021685 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,38223493 0,40198461 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,38223493 0,40180089 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,38223493 0,40161733 ! exocytosis GO:0006887 74 55 0,000 0,38772917 0,40720415 ! mesoderm development GO:0007498 76 55 0,000 0,38772917 0,4070183 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,39317485 0,41254661 ! carbohydrate transport GO:0008643 74 57 0,000 0,39857241 0,4180194 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,39857241 0,41782888 ! camera-type eye development GO:0043010 88 57 0,000 0,39857241 0,41763852 ! developmental maturation GO:0021700 75 57 0,000 0,39857241 0,41744834 ! gonad development GO:0008406 79 57 0,000 0,39857241 0,41725833 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,40392227 0,42266662 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,40922485 0,42802053 ! activation of MAPK activity GO:0000187 84 59 0,000 0,40922485 0,42782598 ! actin filament organization GO:0007015 95 59 0,000 0,40922485 0,4276316 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,40922485 0,4274374 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,41448055 0,43273049 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,41448055 0,43253415 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,41448055 0,43233799 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,41448055 0,43214201 ! fertilization GO:0009566 68 60 0,000 0,41448055 0,4319462 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,41448055 0,43175057 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,4196898 0,43697897 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,4196898 0,43678124 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,4196898 0,43658369 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,4196898 0,43638632 ! extracellular matrix organization GO:0030198 103 61 0,000 0,4196898 0,43618913 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,4196898 0,43599211 ! neurotransmitter transport GO:0006836 81 62 0,000 0,424853 0,44115661 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,424853 0,44095753 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,42997055 0,44606778 ! appendage morphogenesis GO:0035107 93 64 0,000 0,43504286 0,4511265 GO:0035108|limb morphogenesis, ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,43504286 0,4509232 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,43504286 0,45072008 ! reproductive structure development GO:0048608 90 65 0,000 0,44007032 0,45572343 ! appendage development GO:0048736 94 65 0,000 0,44007032 0,45551834 GO:0060173|limb development, ! defense response to bacterium GO:0042742 73 65 0,000 0,44007032 0,45531343 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,44007032 0,4551087 ! protein oligomerization GO:0051259 100 65 0,000 0,44007032 0,45490416 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,44505334 0,45984846 ! antigen processing and presentation GO:0019882 96 66 0,000 0,44505334 0,45964197 ! axon guidance GO:0007411 99 66 0,000 0,44505334 0,45943567 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,44999228 0,46432582 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,44999228 0,4641176 ! learning or memory GO:0007611 123 68 0,000 0,45488756 0,46895625 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,45488756 0,46874614 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,45488756 0,46853622 ! rhythmic process GO:0048511 105 68 0,000 0,45488756 0,46832649 ! inorganic anion transport GO:0015698 93 68 0,000 0,45488756 0,46811695 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,45973954 0,47289845 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,45973954 0,47268706 ! response to drug GO:0042493 108 69 0,000 0,45973954 0,47247585 ! response to metal ion GO:0010038 103 70 0,000 0,46454861 0,47720492 ! eye development GO:0001654 111 70 0,000 0,46454861 0,47699188 ! amine transport GO:0015837 101 70 0,000 0,46454861 0,47677903 ! positive regulation of phosphorylation GO:0042327 102 70 0,000 0,46454861 0,47656637 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,46454861 0,47635391 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,46931515 0,48102712 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,47403953 0,48565297 ! negative regulation of transport GO:0051051 116 73 0,000 0,47872212 0,49023191 ! regulation of blood pressure GO:0008217 107 73 0,000 0,47872212 0,49001374 ! tube morphogenesis GO:0035239 118 73 0,000 0,47872212 0,48979576 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,47872212 0,48957798 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,47872212 0,48936039 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,48336329 0,49388519 ! digestion GO:0007586 97 74 0,000 0,48336329 0,49366588 ! blood coagulation GO:0007596 116 75 0,000 0,48796339 0,49814283 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,48796339 0,49792183 ! tRNA metabolic process GO:0006399 95 76 0,000 0,49252281 0,50235142 ! response to unfolded protein GO:0006986 99 76 0,000 0,49252281 0,50212875 ! regulation of protein transport GO:0051223 114 76 0,000 0,49252281 0,50190627 GO:0070201|regulation of establishment of protein localization, ! cholesterol metabolic process GO:0008203 109 77 0,000 0,49704188 0,50628712 ! sex differentiation GO:0007548 105 77 0,000 0,49704188 0,506063 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,49704188 0,50583908 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,49704188 0,50561536 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,49704188 0,50539183 ! cellular respiration GO:0045333 107 79 0,000 0,50596042 0,51423286 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,50596042 0,51400573 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,50596042 0,51377879 ! hemostasis GO:0007599 125 81 0,000 0,51472182 0,52244491 ! mRNA transport GO:0051028 121 81 0,000 0,51472182 0,52221446 ! response to protein stimulus GO:0051789 111 81 0,000 0,51472182 0,5219842 ! regulation of neurological system process GO:0031644 122 81 0,000 0,51472182 0,52175415 ! ossification GO:0001503 134 82 0,000 0,51904445 0,52590407 GO:0060348|bone development, ! regulation of defense response GO:0031347 117 84 0,000 0,52757527 0,53431226 ! sterol metabolic process GO:0016125 120 84 0,000 0,52757527 0,53407708 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,53178414 0,53810098 ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,53178414 0,53786435 ! transcription initiation GO:0006352 118 85 0,000 0,53178414 0,53762792 ! regulation of protein localization GO:0032880 132 85 0,000 0,53178414 0,53739171 ! regulation of membrane potential GO:0042391 128 85 0,000 0,53178414 0,5371557 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,53178414 0,5369199 ! cellular defense response GO:0006968 102 87 0,000 0,54009043 0,54506713 ! female pregnancy GO:0007565 130 87 0,000 0,54009043 0,54482806 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,5441885 0,54872141 ! establishment of RNA localization GO:0051236 128 88 0,000 0,5441885 0,54848096 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! regulation of neurogenesis GO:0050767 153 89 0,000 0,54825029 0,55233275 ! reproductive developmental process GO:0003006 127 89 0,000 0,54825029 0,55209092 ! hormone metabolic process GO:0042445 121 90 0,000 0,55227612 0,55590156 ! RNA localization GO:0006403 135 91 0,000 0,5562663 0,559673 ! ATP metabolic process GO:0046034 137 91 0,000 0,5562663 0,55942828 ! response to virus GO:0009615 122 91 0,000 0,5562663 0,55918378 ! cell fate commitment GO:0045165 141 92 0,000 0,56022114 0,56291334 ! sulfur metabolic process GO:0006790 118 92 0,000 0,56022114 0,56266752 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,56414096 0,56635714 ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,57569336 0,57770277 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,57569336 0,57745082 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,57947615 0,58099178 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,58694149 0,58822023 ! extracellular structure organization GO:0043062 156 99 0,000 0,58694149 0,58796404 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,59062464 0,59139602 ! divalent metal ion transport GO:0070838 171 100 0,000 0,59062464 0,59113867 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,59062464 0,59088154 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,59062464 0,59062464