pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/941-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of lipid kinase activity GO:0043550 13 7 3,000 6,904E-08 1,661E-04 ! establishment or maintenance of cell polarity GO:0007163 83 37 5,000 1,701E-07 2,046E-04 ! actin filament-based movement GO:0030048 43 20 4,000 1,891E-07 1,517E-04 ! myeloid cell differentiation GO:0030099 111 65 6,000 2,85E-07 1,714E-04 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 3,000 4,077E-07 1,962E-04 GO:0007520|myoblast fusion, ! syncytium formation GO:0006949 18 11 3,000 6,373E-07 2,555E-04 ! ribosomal large subunit biogenesis GO:0042273 13 13 3,000 1,366E-06 4,696E-04 ! myotube differentiation GO:0014902 25 14 3,000 1,903E-06 5,722E-04 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 2,000 2,988E-06 7,987E-04 ! regulation of keratinocyte differentiation GO:0045616 6 5 2,000 2,988E-06 7,188E-04 ! filopodium assembly GO:0046847 32 16 3,000 3,423E-06 7,487E-04 ! leukocyte differentiation GO:0002521 202 96 6,000 4,09E-06 8,201E-04 ! endothelial cell migration GO:0043542 28 17 3,000 4,452E-06 8,24E-04 ! microspike assembly GO:0030035 36 17 3,000 4,452E-06 7,652E-04 ! nuclear migration GO:0007097 12 6 2,000 5,945E-06 9,536E-04 ! establishment of spindle localization GO:0051293 12 6 2,000 5,945E-06 8,94E-04 GO:0051653|spindle localization, ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 5,945E-06 8,414E-04 GO:0031272|regulation of pseudopodium assembly, ! plasma membrane fusion GO:0045026 28 19 3,000 7,175E-06 9,59E-04 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 4,000 9,198E-06 1,165E-03 ! macrophage differentiation GO:0030225 11 7 2,000 1,035E-05 1,245E-03 ! regulation of epidermal cell differentiation GO:0045604 8 7 2,000 1,035E-05 1,186E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 1,45E-05 1,586E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 3,000 1,605E-05 1,679E-03 ! UTP metabolic process GO:0046051 8 8 2,000 1,648E-05 1,652E-03 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 1,648E-05 1,586E-03 ! establishment of nucleus localization GO:0040023 16 8 2,000 1,648E-05 1,525E-03 ! positive regulation of epidermis development GO:0045684 13 8 2,000 1,648E-05 1,469E-03 ! CTP metabolic process GO:0046036 9 9 2,000 2,46E-05 2,114E-03 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 9 9 2,000 2,46E-05 2,041E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 2,667E-05 2,139E-03 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 3,497E-05 2,714E-03 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 2,000 3,497E-05 2,629E-03 ! establishment of cell polarity GO:0030010 16 10 2,000 3,497E-05 2,549E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 3,000 4,17E-05 2,951E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 4,171E-05 2,867E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 5,000 4,598E-05 3,073E-03 ! nucleus localization GO:0051647 19 11 2,000 4,784E-05 3,111E-03 ! establishment of organelle localization GO:0051656 109 59 4,000 4,933E-05 3,124E-03 ! interphase GO:0051325 213 98 5,000 5,476E-05 3,378E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 6,347E-05 3,818E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 6,347E-05 3,725E-03 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 2,000 6,347E-05 3,636E-03 ! steroid hormone receptor signaling pathway GO:0030518 129 63 4,000 6,777E-05 3,792E-03 ! regulation of epidermis development GO:0045682 19 13 2,000 8,21E-05 4,49E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 9,11E-05 4,871E-03 ! negative regulation of kinase activity GO:0033673 131 68 4,000 9,78E-05 5,115E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 4,000 9,78E-05 5,007E-03 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 2,000 1,04E-04 5,212E-03 ! negative regulation of transferase activity GO:0051348 140 72 4,000 1,284E-04 6,307E-03 ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 2,000 1,293E-04 6,223E-03 ! detection of bacterium GO:0016045 18 15 2,000 1,293E-04 6,101E-03 ! meiosis GO:0007126 121 74 4,000 1,463E-04 6,768E-03 GO:0051327|M phase of meiotic cell cycle, ! organelle localization GO:0051640 136 74 4,000 1,463E-04 6,64E-03 ! cytokinesis GO:0000910 72 40 3,000 1,514E-04 6,747E-03 ! meiotic cell cycle GO:0051321 122 75 4,000 1,559E-04 6,819E-03 ! negative regulation of cell cycle process GO:0010948 32 17 2,000 1,914E-04 8,222E-03 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 2,000 1,914E-04 8,078E-03 ! muscle cell differentiation GO:0042692 159 80 4,000 2,113E-04 8,765E-03 ! G1 phase GO:0051318 40 19 2,000 2,7E-04 0,01101035 ! estrogen receptor signaling pathway GO:0030520 38 19 2,000 2,7E-04 0,01082684 ! positive regulation of DNA binding GO:0043388 73 47 3,000 2,849E-04 0,01123597 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 2,000 3,161E-04 0,01226548 ! regulation of DNA binding GO:0051101 155 88 4,000 3,297E-04 0,01258976 ! negative regulation of immune system process GO:0002683 95 50 3,000 3,621E-04 0,01361129 ! regulation of cell cycle process GO:0010564 149 90 4,000 3,658E-04 0,01354133 ! regulation of Rho GTPase activity GO:0032319 43 21 2,000 3,669E-04 0,01337587 ! detection of biotic stimulus GO:0009595 29 21 2,000 3,669E-04 0,01317623 ! positive regulation of binding GO:0051099 78 51 3,000 3,908E-04 0,01382807 ! regulation of cell shape GO:0008360 125 51 3,000 3,908E-04 0,01362767 ! membrane fusion GO:0006944 110 52 3,000 4,212E-04 0,01447619 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 4,227E-04 0,01432584 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 4,227E-04 0,01412687 ! benzene and derivative metabolic process GO:0042537 12 5 1,000 4,461E-04 0,01470293 ! selenocysteine incorporation GO:0001514 12 5 1,000 4,461E-04 0,01450425 GO:0006451|translational readthrough, ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 4,461E-04 0,01431086 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 4,461E-04 0,01412256 ! tryptophan metabolic process GO:0006568 9 5 1,000 4,461E-04 0,01393915 ! meiotic chromosome segregation GO:0045132 7 5 1,000 4,461E-04 0,01376044 ! negative regulation of T cell mediated immunity GO:0002710 12 5 1,000 4,461E-04 0,01358626 GO:0002707|negative regulation of lymphocyte mediated immunity, ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 1,000 4,461E-04 0,01341643 ! metaphase GO:0051323 8 5 1,000 4,461E-04 0,01325079 ! activation of Ras GTPase activity GO:0032856 10 5 1,000 4,461E-04 0,0130892 GO:0032862|activation of Rho GTPase activity, ! metallo-sulfur cluster assembly GO:0031163 5 5 1,000 4,461E-04 0,0129315 GO:0016226|iron-sulfur cluster assembly, ! stem cell division GO:0017145 11 5 1,000 4,461E-04 0,01277755 GO:0048103|somatic stem cell division, ! pyrimidine nucleoside metabolic process GO:0006213 29 23 2,000 4,838E-04 0,0136931 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 5,501E-04 0,01539072 ! skeletal muscle fiber development GO:0048741 111 56 3,000 5,595E-04 0,01547381 ! skeletal muscle tissue development GO:0007519 186 99 4,000 5,67E-04 0,01550153 GO:0060538|skeletal muscle organ development, ! muscle fiber development GO:0048747 112 57 3,000 5,986E-04 0,01618257 ! dicarboxylic acid metabolic process GO:0043648 42 25 2,000 6,22E-04 0,01662944 ! male meiosis GO:0007140 7 6 1,000 6,662E-04 0,0176134 ! response to interferon-gamma GO:0034341 15 6 1,000 6,662E-04 0,01742195 ! glutamate catabolic process GO:0006538 10 6 1,000 6,662E-04 0,01723461 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 1,000 6,662E-04 0,01705127 GO:0033135|regulation of peptidyl-serine phosphorylation, ! monocyte differentiation GO:0030224 12 6 1,000 6,662E-04 0,01687178 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 6,662E-04 0,01669603 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 1,000 6,662E-04 0,01652391 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 1,000 6,662E-04 0,0163553 ! negative regulation of B cell activation GO:0050869 13 6 1,000 6,662E-04 0,01619009 ! DNA catabolic process GO:0006308 86 59 3,000 6,825E-04 0,01642126 ! regulation of protein complex assembly GO:0043254 117 61 3,000 7,744E-04 0,01844807 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 7,833E-04 0,01847614 ! regulation of chromosome organization GO:0033044 42 27 2,000 7,833E-04 0,01829676 ! regulation of lipid metabolic process GO:0019216 115 63 3,000 8,747E-04 0,02023674 ! cellular amino acid catabolic process GO:0009063 101 63 3,000 8,747E-04 0,02004401 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 9,285E-04 0,02107531 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 9,285E-04 0,02087835 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 9,285E-04 0,02068503 ! aspartate family amino acid catabolic process GO:0009068 9 7 1,000 9,285E-04 0,02049526 ! lymph node development GO:0048535 10 7 1,000 9,285E-04 0,02030894 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 1,000 9,285E-04 0,02012598 ! cell projection assembly GO:0030031 120 66 3,000 1,042E-03 0,02238196 ! regulation of B cell activation GO:0050864 50 30 2,000 1,071E-03 0,02280752 ! negative regulation of cell growth GO:0030308 132 67 3,000 1,102E-03 0,02326336 ! homeostasis of number of cells GO:0048872 114 67 3,000 1,102E-03 0,02306107 ! erythrocyte differentiation GO:0030218 55 31 2,000 1,18E-03 0,02447665 ! negative regulation of cell size GO:0045792 134 69 3,000 1,23E-03 0,02529946 ! carbohydrate phosphorylation GO:0046835 11 8 1,000 1,233E-03 0,02513073 ! glycine catabolic process GO:0006546 13 8 1,000 1,233E-03 0,02491955 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,233E-03 0,02471188 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 1,233E-03 0,02450765 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,233E-03 0,02430677 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 1,000 1,233E-03 0,02410916 ! NAD biosynthetic process GO:0009435 13 8 1,000 1,233E-03 0,02391473 ! spindle organization GO:0007051 46 32 2,000 1,296E-03 0,02494033 ! amine catabolic process GO:0009310 117 71 3,000 1,368E-03 0,02612892 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 2,000 1,548E-03 0,02932387 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,578E-03 0,02965453 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 1,578E-03 0,02942465 ! base-excision repair, AP site formation GO:0006285 14 9 1,000 1,578E-03 0,02919831 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 1,000 1,578E-03 0,02897542 GO:0002820|negative regulation of adaptive immune response, ! regulation of macrophage differentiation GO:0045649 15 9 1,000 1,578E-03 0,02875591 ! serine family amino acid catabolic process GO:0009071 16 9 1,000 1,578E-03 0,0285397 ! lymphocyte differentiation GO:0030098 167 75 3,000 1,676E-03 0,03009826 ! steroid biosynthetic process GO:0006694 131 76 3,000 1,76E-03 0,03137075 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,829E-03 0,03235179 ! negative regulation of organelle organization GO:0010639 161 78 3,000 1,937E-03 0,03401206 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,963E-03 0,03422965 ! regulation of phosphatase activity GO:0010921 28 10 1,000 1,963E-03 0,0339834 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 1,963E-03 0,03374066 ! positive regulation of Rho GTPase activity GO:0032321 24 10 1,000 1,963E-03 0,03350136 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 1,000 1,963E-03 0,03326544 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 1,000 1,963E-03 0,03303281 ! negative regulation of immune effector process GO:0002698 20 10 1,000 1,963E-03 0,03280342 ! meiosis I GO:0007127 65 37 2,000 1,98E-03 0,03285837 ! erythrocyte homeostasis GO:0034101 64 38 2,000 2,139E-03 0,03525585 ! cortical actin cytoskeleton organization GO:0030866 30 11 1,000 2,389E-03 0,03910083 ! thyroid gland development GO:0030878 26 11 1,000 2,389E-03 0,03883664 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 2,389E-03 0,03857599 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 2,389E-03 0,03831882 ! indolalkylamine metabolic process GO:0006586 17 11 1,000 2,389E-03 0,03806505 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 1,000 2,389E-03 0,03781462 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of lipoprotein lipase activity GO:0051004 23 11 1,000 2,389E-03 0,03756747 ! regulation of embryonic development GO:0045995 27 11 1,000 2,389E-03 0,03732352 ! ribonucleoside metabolic process GO:0009119 55 40 2,000 2,481E-03 0,03851092 ! negative regulation of growth GO:0045926 155 84 3,000 2,539E-03 0,03915879 ! regulation of T cell differentiation GO:0045580 70 41 2,000 2,664E-03 0,04081999 ! cortical cytoskeleton organization GO:0030865 31 12 1,000 2,854E-03 0,04346104 ! membrane protein proteolysis GO:0033619 25 12 1,000 2,854E-03 0,0431877 GO:0006509|membrane protein ectodomain proteolysis, ! entry into host cell GO:0030260 32 12 1,000 2,854E-03 0,04291778 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 2,854E-03 0,04265121 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,854E-03 0,04238793 ! aromatic amino acid family catabolic process GO:0009074 18 12 1,000 2,854E-03 0,04212788 ! biogenic amine catabolic process GO:0042402 23 12 1,000 2,854E-03 0,041871 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 2,854E-03 0,04161724 GO:0042130|negative regulation of T cell proliferation, ! nitrogen compound catabolic process GO:0044270 143 87 3,000 2,884E-03 0,04179403 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 3,053E-03 0,04399108 ! regulation of cell morphogenesis GO:0022604 215 89 3,000 3,13E-03 0,04482937 ! B cell differentiation GO:0030183 107 44 2,000 3,261E-03 0,0464218 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 3,358E-03 0,04752615 GO:0000725|recombinational repair, ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 3,358E-03 0,04724822 ! positive regulation of Ras GTPase activity GO:0032320 35 13 1,000 3,358E-03 0,04697352 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 1,000 3,358E-03 0,04670199 ! endocrine pancreas development GO:0031018 22 13 1,000 3,358E-03 0,04643359 ! deoxyribonucleotide catabolic process GO:0009264 19 13 1,000 3,358E-03 0,04616826 ! cell growth GO:0016049 84 45 2,000 3,476E-03 0,04752463 ! lactation GO:0007595 26 14 1,000 3,9E-03 0,05301878 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 3,9E-03 0,05272092 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 3,9E-03 0,05242639 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 3,9E-03 0,05213514 ! activation of caspase activity GO:0006919 84 48 2,000 4,175E-03 0,05550073 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 4,175E-03 0,05519578 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 4,175E-03 0,05489417 ! carboxylic acid catabolic process GO:0046395 156 98 3,000 4,419E-03 0,05778555 GO:0016054|organic acid catabolic process, ! endocrine system development GO:0035270 104 49 2,000 4,426E-03 0,05755805 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 4,481E-03 0,05795805 ! regulation of ATPase activity GO:0043462 21 15 1,000 4,481E-03 0,05764811 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 4,481E-03 0,05734147 ! regulation of cell projection organization GO:0031344 121 50 2,000 4,685E-03 0,05964186 ! cell cycle arrest GO:0007050 213 100 3,000 4,748E-03 0,06011877 ! viral infectious cycle GO:0019058 99 51 2,000 4,953E-03 0,06239823 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 4,953E-03 0,06207324 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 5,098E-03 0,0635533 ! cellular amino acid derivative catabolic process GO:0042219 29 16 1,000 5,098E-03 0,06322571 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 1,000 5,098E-03 0,06290147 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 5,098E-03 0,06258055 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 5,098E-03 0,06226288 ! glutamate metabolic process GO:0006536 22 16 1,000 5,098E-03 0,06194842 ! regulation of dephosphorylation GO:0035303 43 16 1,000 5,098E-03 0,06163712 ! negative regulation of immune response GO:0050777 35 16 1,000 5,098E-03 0,06132894 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 1,000 5,752E-03 0,06885491 GO:0019692|deoxyribose phosphate metabolic process, ! glycine metabolic process GO:0006544 28 17 1,000 5,752E-03 0,06851404 ! NAD metabolic process GO:0019674 29 17 1,000 5,752E-03 0,06817653 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 5,752E-03 0,06784233 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 1,000 5,752E-03 0,06751139 ! heterocycle catabolic process GO:0046700 85 54 2,000 5,814E-03 0,06790011 ! positive regulation of caspase activity GO:0043280 95 55 2,000 6,119E-03 0,07112025 GO:0010952|positive regulation of peptidase activity, ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 6,443E-03 0,07452449 ! aromatic compound catabolic process GO:0019439 27 18 1,000 6,443E-03 0,07416792 ! lipid phosphorylation GO:0046834 35 19 1,000 7,169E-03 0,0821349 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 7,169E-03 0,08174563 ! purine nucleotide catabolic process GO:0006195 29 19 1,000 7,169E-03 0,08136004 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 7,788E-03 0,08796835 ! nucleoside metabolic process GO:0009116 81 60 2,000 7,788E-03 0,08755728 ! protein amino acid acetylation GO:0006473 39 20 1,000 7,93E-03 0,08874564 ! response to vitamin GO:0033273 31 20 1,000 7,93E-03 0,08833478 ! pancreas development GO:0031016 35 20 1,000 7,93E-03 0,08792771 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 7,93E-03 0,08752437 ! D-ribose metabolic process GO:0006014 29 20 1,000 7,93E-03 0,08712472 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 1,000 7,93E-03 0,0867287 ! negative regulation of T cell activation GO:0050868 40 20 1,000 7,93E-03 0,08633626 ! viral reproductive process GO:0022415 126 62 2,000 8,523E-03 0,09237129 ! regulation of cell killing GO:0031341 42 21 1,000 8,726E-03 0,09415175 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 8,726E-03 0,09373143 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 8,726E-03 0,09331485 ! DNA modification GO:0006304 34 21 1,000 8,726E-03 0,09290195 ! response to cytokine stimulus GO:0034097 63 21 1,000 8,726E-03 0,09249269 ! regulation of mitosis GO:0007088 105 63 2,000 8,905E-03 0,09397595 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 2,000 8,905E-03 0,09356558 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 9,557E-03 0,09997266 ! deoxyribonucleotide metabolic process GO:0009262 32 22 1,000 9,557E-03 0,09953987 ! apoptotic nuclear changes GO:0030262 32 22 1,000 9,557E-03 0,09911082 ! positive regulation of B cell activation GO:0050871 38 22 1,000 9,557E-03 0,09868545 ! aromatic amino acid family metabolic process GO:0009072 32 22 1,000 9,557E-03 0,09826372 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 9,557E-03 0,09784558 ! barbed-end actin filament capping GO:0051016 50 23 1,000 0,01042092 0,10624042 GO:0051693|actin filament capping, ! viral genome replication GO:0019079 41 23 1,000 0,01042092 0,10579215 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 0,01042092 0,10534764 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 1,000 0,01042092 0,10490686 ! response to ethanol GO:0045471 46 23 1,000 0,01042092 0,10446975 ! fatty acid transport GO:0015908 44 23 1,000 0,01042092 0,10403626 ! viral reproduction GO:0016032 134 68 2,000 0,01096715 0,10903705 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 0,01131827 0,11206482 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 0,01131827 0,11160554 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 0,01131827 0,11115001 ! pentose metabolic process GO:0019321 35 24 1,000 0,01131827 0,11069818 ! glutamine family amino acid catabolic process GO:0009065 39 24 1,000 0,01131827 0,11025001 ! aspartate family amino acid metabolic process GO:0009066 42 24 1,000 0,01131827 0,10980545 ! cell cycle checkpoint GO:0000075 137 69 2,000 0,01140974 0,1102483 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 0,01224837 0,11787835 ! interaction with host GO:0051701 62 25 1,000 0,01224837 0,11740871 ! somitogenesis GO:0001756 43 25 1,000 0,01224837 0,1169428 ! B cell activation GO:0042113 160 71 2,000 0,01232548 0,11721382 ! regulation of caspase activity GO:0043281 122 72 2,000 0,0127987 0,12123496 ! negative regulation of actin filament depolymerization GO:0030835 55 26 1,000 0,01321076 0,12464743 ! negative regulation of actin filament polymerization GO:0030837 53 26 1,000 0,01321076 0,12416052 ! initiation of viral infection GO:0019059 57 26 1,000 0,01321076 0,12367741 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 0,01321076 0,12319804 ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,01321076 0,12272237 GO:0045840|positive regulation of mitosis, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 1,000 0,01321076 0,12225036 ! regulation of transcription factor activity GO:0051090 126 74 2,000 0,01377603 0,12699279 GO:0090046|regulation of transcription regulator activity, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 0,01377603 0,12650809 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01420496 0,12995109 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 1,000 0,01420496 0,12945885 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,01420496 0,12897033 ! base-excision repair GO:0006284 41 27 1,000 0,01420496 0,12848548 ! negative regulation of protein polymerization GO:0032272 55 27 1,000 0,01420496 0,12800426 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 0,01420496 0,12752663 ! regulation of actin filament depolymerization GO:0030834 58 28 1,000 0,0152305 0,13622523 ! negative regulation of protein modification process GO:0031400 60 28 1,000 0,0152305 0,13572069 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 0,0152305 0,13521988 ! vitamin biosynthetic process GO:0009110 39 28 1,000 0,0152305 0,13472275 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 0,0152305 0,13422926 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 0,01531961 0,13452182 ! complement activation, classical pathway GO:0006958 48 29 1,000 0,01628692 0,14249575 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,01628692 0,14197946 ! regulation of peptidase activity GO:0052547 134 79 2,000 0,01640067 0,14245494 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 0,01640067 0,14194251 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01737376 0,14982532 ! nicotinamide metabolic process GO:0006769 52 30 1,000 0,01737376 0,14929023 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,01737376 0,14875895 ! T cell activation GO:0042110 168 81 2,000 0,01752352 0,1495092 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 0,01752352 0,1489809 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 153 81 2,000 0,01752352 0,14845632 ! alkaloid metabolic process GO:0009820 53 31 1,000 0,01849056 0,15609929 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 1,000 0,01849056 0,15555349 ! serine family amino acid metabolic process GO:0009069 49 31 1,000 0,01849056 0,15501149 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 0,01849056 0,15447326 GO:0043433|negative regulation of transcription factor activity, ! regulation of ligase activity GO:0051340 142 84 2,000 0,0192864 0,1605643 ! metanephros development GO:0001656 74 32 1,000 0,01963689 0,16291844 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 0,01963689 0,16235859 ! positive regulation of cell activation GO:0050867 145 85 2,000 0,01989503 0,16392962 GO:0002696|positive regulation of leukocyte activation, ! pyridine nucleotide metabolic process GO:0019362 55 33 1,000 0,02081228 0,17090221 ! adult locomotory behavior GO:0008344 59 33 1,000 0,02081228 0,17032091 ! positive regulation of protein modification process GO:0031401 136 88 2,000 0,02178403 0,17766909 ! gland development GO:0048732 206 88 2,000 0,02178403 0,17706885 ! xenobiotic metabolic process GO:0006805 51 34 1,000 0,02201631 0,17835433 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 0,02201631 0,17775582 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,02201631 0,17716132 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,02243475 0,17992666 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,02324853 0,18583378 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,02324853 0,18521843 ! cofactor biosynthetic process GO:0051188 139 91 2,000 0,02376775 0,18873004 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,02450852 0,19397205 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,02450852 0,19333608 ! sister chromatid segregation GO:0000819 58 37 1,000 0,02579585 0,20282621 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,02579585 0,20216554 ! regulation of protein stability GO:0031647 73 37 1,000 0,02579585 0,20150915 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 0,02579585 0,20085702 ! regulation of T cell activation GO:0050863 158 94 2,000 0,02584614 0,20059941 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 0,02655995 0,20547669 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 1,000 0,0271101 0,20906058 GO:0006956|complement activation, ! nucleus organization GO:0006997 67 38 1,000 0,0271101 0,20839266 ! nucleotide catabolic process GO:0009166 61 38 1,000 0,0271101 0,20772898 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,0271101 0,20706953 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 2,000 0,02728426 0,20774028 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! detection of stimulus GO:0051606 151 96 2,000 0,02728426 0,20708495 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 2,000 0,02801905 0,21199317 ! protein ubiquitination GO:0016567 217 97 2,000 0,02801905 0,21132862 ! mammary gland development GO:0030879 86 39 1,000 0,02845085 0,21391482 ! segmentation GO:0035282 67 39 1,000 0,02845085 0,21324842 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 0,02845085 0,21258616 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 0,02845085 0,211928 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 2,000 0,02876431 0,21360161 ! negative regulation of binding GO:0051100 72 40 1,000 0,02981769 0,22074262 ! mesenchymal cell development GO:0014031 87 40 1,000 0,02981769 0,22006549 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! cellular amide metabolic process GO:0043603 67 41 1,000 0,0312102 0,22963835 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,0312102 0,22893823 ! T cell differentiation GO:0030217 81 41 1,000 0,0312102 0,22824237 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,0312102 0,22755073 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,03262799 0,237169 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,03262799 0,23645464 ! monocarboxylic acid transport GO:0015718 85 42 1,000 0,03262799 0,23574457 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 0,03262799 0,23503874 ! neuron migration GO:0001764 79 42 1,000 0,03262799 0,23433714 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,03262799 0,2336397 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,0332528 0,23740723 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,0332528 0,23670484 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0332528 0,23600659 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,0332528 0,23531246 ! neuron fate determination GO:0048664 7 5 0,000 0,0332528 0,23462239 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0332528 0,23393636 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,0332528 0,23325433 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,0332528 0,23257627 ! polyol transport GO:0015791 12 5 0,000 0,0332528 0,23190213 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,0332528 0,23123189 ! response to superoxide GO:0000303 10 5 0,000 0,0332528 0,23056552 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,0332528 0,22990298 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,0332528 0,22924423 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,0332528 0,22858924 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0332528 0,22793799 ! female meiosis GO:0007143 7 5 0,000 0,0332528 0,22729044 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,0332528 0,22664656 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0332528 0,22600631 ! cobalt ion transport GO:0006824 11 5 0,000 0,0332528 0,22536968 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,0332528 0,22473662 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,0332528 0,2241071 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,0332528 0,2234811 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0332528 0,22285859 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0332528 0,22223954 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,0332528 0,22162392 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,0332528 0,2210117 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,0332528 0,22040285 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,0332528 0,21979735 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0332528 0,21919517 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,0332528 0,21859627 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,0332528 0,21800064 ! negative chemotaxis GO:0050919 14 5 0,000 0,0332528 0,21740825 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0332528 0,21681907 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0332528 0,21623307 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,0332528 0,21565023 ! behavioral response to pain GO:0048266 9 5 0,000 0,0332528 0,21507053 ! clathrin coat assembly GO:0048268 14 5 0,000 0,0332528 0,21449393 ! Notch receptor processing GO:0007220 8 5 0,000 0,0332528 0,21392042 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0332528 0,21334996 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0332528 0,21278254 ! micturition GO:0060073 9 5 0,000 0,0332528 0,21221813 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0332528 0,21165671 ! copulation GO:0007620 9 5 0,000 0,0332528 0,21109825 ! glial cell fate commitment GO:0021781 13 5 0,000 0,0332528 0,21054272 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,0332528 0,20999012 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0332528 0,20944041 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0332528 0,20889356 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0332528 0,20834957 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,0332528 0,2078084 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0332528 0,20727004 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0332528 0,20673446 ! grooming behavior GO:0007625 6 5 0,000 0,0332528 0,20620164 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0332528 0,20567156 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,0332528 0,20514419 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0332528 0,20461953 ! response to protozoan GO:0001562 10 5 0,000 0,0332528 0,20409754 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,0332528 0,20357821 ! lymph vessel development GO:0001945 10 5 0,000 0,0332528 0,20306151 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,0332528 0,20254743 ! endochondral ossification GO:0001958 16 5 0,000 0,0332528 0,20203595 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0332528 0,20152704 ! parathyroid gland development GO:0060017 13 5 0,000 0,0332528 0,20102069 ! anagen GO:0042640 6 5 0,000 0,0332528 0,20051688 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0332528 0,20001559 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,0332528 0,1995168 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,0332528 0,19902049 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,0332528 0,19852664 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,0332528 0,19803524 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,0332528 0,19754626 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,0332528 0,19705969 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,0332528 0,19657552 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0332528 0,19609371 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0332528 0,19561427 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,0332528 0,19513716 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,0332528 0,19466237 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,0332528 0,19418989 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0332528 0,1937197 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,0332528 0,19325178 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,0332528 0,19278611 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,0332528 0,19232268 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0332528 0,19186148 ! histidine catabolic process GO:0006548 6 5 0,000 0,0332528 0,19140248 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0332528 0,19094567 ! microvillus organization GO:0032528 7 5 0,000 0,0332528 0,19049104 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,0332528 0,19003856 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,0332528 0,18958824 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0332528 0,18914004 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,0332528 0,18869395 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0332528 0,18824997 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,0332528 0,18780806 ! polyol catabolic process GO:0046174 7 5 0,000 0,0332528 0,18736823 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0332528 0,18693046 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0332528 0,18649472 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0332528 0,18606101 ! muscle cell migration GO:0014812 8 5 0,000 0,0332528 0,18562932 ! mitochondrial fission GO:0000266 8 5 0,000 0,0332528 0,18519962 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,0332528 0,18477191 ! mRNA transcription GO:0009299 9 5 0,000 0,0332528 0,18434616 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,0332528 0,18392238 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,0332528 0,18350054 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,0332528 0,18308063 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0332528 0,18266264 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0332528 0,18224655 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0332528 0,18183235 ! response to food GO:0032094 6 5 0,000 0,0332528 0,18142003 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,0332528 0,18100958 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,0332528 0,18060098 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,0332528 0,18019422 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0332528 0,17978929 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,0332528 0,17938618 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,0332528 0,17898487 ! forebrain neuron development GO:0021884 13 5 0,000 0,0332528 0,17858535 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0332528 0,17818761 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,0332528 0,17779163 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0332528 0,17739742 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0332528 0,17700495 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,0332528 0,17661421 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,0332528 0,17622519 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0332528 0,17583788 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,0332528 0,17545227 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,0332528 0,17506835 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,0332528 0,1746861 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,0332528 0,17430552 ! basic amino acid transport GO:0015802 11 5 0,000 0,0332528 0,1739266 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0332528 0,17354932 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,0332528 0,17317367 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0332528 0,17279964 ! depyrimidination GO:0045008 10 5 0,000 0,0332528 0,17242723 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0332528 0,17205642 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0332528 0,1716872 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,0332528 0,17131956 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,0332528 0,17095349 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,0332528 0,17058899 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0332528 0,17022603 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0332528 0,16986462 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0332528 0,16950474 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,0332528 0,16914637 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,0332528 0,16878953 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0332528 0,16843418 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0332528 0,16808033 ! response to arsenic GO:0046685 10 5 0,000 0,0332528 0,16772796 ! mast cell degranulation GO:0043303 7 5 0,000 0,0332528 0,16737706 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,0332528 0,16702763 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,0332528 0,16667966 ! response to cadmium ion GO:0046686 7 5 0,000 0,0332528 0,16633313 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,0332528 0,16598804 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,0332528 0,16564438 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0332528 0,16530214 ! decidualization GO:0046697 11 5 0,000 0,0332528 0,16496131 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,0332528 0,16462188 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,0332528 0,16428385 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0332528 0,1639472 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,0332528 0,16361193 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0332528 0,16327803 ! neural tube patterning GO:0021532 7 5 0,000 0,0332528 0,16294549 ! embryonic cleavage GO:0040016 6 5 0,000 0,0332528 0,1626143 ! peroxisome fission GO:0016559 5 5 0,000 0,0332528 0,16228445 ! histone demethylation GO:0016577 10 5 0,000 0,0332528 0,16195594 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,0332528 0,16162876 ! mitotic recombination GO:0006312 9 5 0,000 0,0332528 0,16130289 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0332528 0,16097834 ! metaphase plate congression GO:0051310 7 5 0,000 0,0332528 0,16065509 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0332528 0,16033314 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,0332528 0,16001247 ! enteric nervous system development GO:0048484 8 5 0,000 0,0332528 0,15969308 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,0332528 0,15937497 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,0332528 0,15905812 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,0332528 0,15874253 ! muscle cell proliferation GO:0033002 11 5 0,000 0,0332528 0,15842819 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0332528 0,15811509 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,0332528 0,15780323 ! plasminogen activation GO:0031639 5 5 0,000 0,0332528 0,15749259 ! B cell homeostasis GO:0001782 13 5 0,000 0,0332528 0,15718317 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,0332528 0,15687497 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0332528 0,15656798 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,0332528 0,15626218 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0332528 0,15595757 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0332528 0,15565415 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0332528 0,15535191 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0332528 0,15505084 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0332528 0,15475094 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,0332528 0,15445219 ! response to redox state GO:0051775 5 5 0,000 0,0332528 0,1541546 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,0332528 0,15385814 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,0332528 0,15356283 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,0332528 0,15326865 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0332528 0,15297559 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,0332528 0,15268366 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0332528 0,15239283 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,0332528 0,15210311 ! striatum development GO:0021756 9 5 0,000 0,0332528 0,15181449 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,0332528 0,15152696 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0332528 0,15124052 ! glial cell migration GO:0008347 11 5 0,000 0,0332528 0,15095516 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,0332528 0,15067088 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,0332528 0,15038766 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0332528 0,15010551 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0332528 0,14982441 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0332528 0,14954437 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0332528 0,14926536 ! neuroprotection GO:0043526 6 5 0,000 0,0332528 0,1489874 ! neural plate development GO:0001840 8 5 0,000 0,0332528 0,14871047 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,0332528 0,14843457 ! regulation of sensory perception GO:0051931 7 5 0,000 0,0332528 0,1481597 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0332528 0,14788583 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,0332528 0,14761298 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,0332528 0,14734113 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,0332528 0,14707029 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0332528 0,14680043 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0332528 0,14653157 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0332528 0,14626368 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0332528 0,14599678 ! spindle assembly GO:0051225 6 5 0,000 0,0332528 0,14573085 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,0332528 0,14546588 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0332528 0,14520188 ! drug metabolic process GO:0017144 6 5 0,000 0,0332528 0,14493883 ! phospholipid scrambling GO:0017121 8 5 0,000 0,0332528 0,14467674 ! organ regeneration GO:0031100 7 5 0,000 0,0332528 0,14441559 ! carnitine metabolic process GO:0009437 7 5 0,000 0,0332528 0,14415538 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,0332528 0,14389611 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0332528 0,14363777 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,03407065 0,14690678 ! double-strand break repair GO:0006302 81 44 1,000 0,03553779 0,15295872 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 0,03553779 0,15268558 ! activation of adenylate cyclase activity GO:0007190 91 44 1,000 0,03553779 0,15241341 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 0,03702902 0,15852636 ! glycolysis GO:0006096 65 45 1,000 0,03702902 0,15824478 ! leukocyte migration GO:0050900 68 45 1,000 0,03702902 0,15796421 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 0,03702902 0,15768462 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 1,000 0,03702902 0,15740603 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 1,000 0,03854394 0,16355682 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,03854394 0,16326887 ! pigmentation GO:0043473 100 46 1,000 0,03854394 0,16298193 ! response to insulin stimulus GO:0032868 95 46 1,000 0,03854394 0,16269599 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03977012 0,16757779 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03977012 0,16728482 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03977012 0,16699288 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03977012 0,16670195 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03977012 0,16641203 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03977012 0,16612312 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03977012 0,16583521 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03977012 0,1655483 ! sleep GO:0030431 13 6 0,000 0,03977012 0,16526238 ! response to oxygen radical GO:0000305 11 6 0,000 0,03977012 0,16497745 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03977012 0,16469349 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03977012 0,16441051 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03977012 0,16412851 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03977012 0,16384746 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03977012 0,16356738 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03977012 0,16328826 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03977012 0,16301008 ! forebrain regionalization GO:0021871 8 6 0,000 0,03977012 0,16273285 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03977012 0,16245657 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03977012 0,16218122 ! response to zinc ion GO:0010043 9 6 0,000 0,03977012 0,1619068 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03977012 0,16163331 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03977012 0,16136074 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03977012 0,16108909 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03977012 0,16081835 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03977012 0,16054852 ! malate metabolic process GO:0006108 11 6 0,000 0,03977012 0,1602796 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03977012 0,16001157 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03977012 0,15974444 ! protein refolding GO:0042026 15 6 0,000 0,03977012 0,1594782 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03977012 0,15921284 ! opsonization GO:0008228 8 6 0,000 0,03977012 0,15894837 ! mating behavior GO:0007617 7 6 0,000 0,03977012 0,15868477 ! neuron remodeling GO:0016322 15 6 0,000 0,03977012 0,15842205 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03977012 0,1581602 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03977012 0,15789921 ! equilibrioception GO:0050957 14 6 0,000 0,03977012 0,15763908 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03977012 0,1573798 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03977012 0,15712138 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03977012 0,1568638 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03977012 0,15660707 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03977012 0,15635117 ! toxin metabolic process GO:0009404 11 6 0,000 0,03977012 0,15609612 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03977012 0,15584189 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03977012 0,15558849 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03977012 0,15533591 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03977012 0,15508415 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03977012 0,1548332 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03977012 0,15458307 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03977012 0,15433374 ! thymic T cell selection GO:0045061 12 6 0,000 0,03977012 0,15408522 ! protein lipoylation GO:0009249 10 6 0,000 0,03977012 0,15383749 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03977012 0,15359056 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03977012 0,15334442 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03977012 0,15309907 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03977012 0,1528545 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03977012 0,15261072 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03977012 0,1523677 ! response to pH GO:0009268 10 6 0,000 0,03977012 0,15212547 ! hyperosmotic response GO:0006972 9 6 0,000 0,03977012 0,151884 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03977012 0,15164329 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03977012 0,15140335 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03977012 0,15116417 ! urea metabolic process GO:0019627 7 6 0,000 0,03977012 0,15092574 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03977012 0,15068806 ! neutrophil activation GO:0042119 8 6 0,000 0,03977012 0,15045113 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03977012 0,15021494 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03977012 0,1499795 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03977012 0,14974479 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03977012 0,14951081 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03977012 0,14927756 ! neuron apoptosis GO:0051402 9 6 0,000 0,03977012 0,14904504 ! nucleoside salvage GO:0043174 9 6 0,000 0,03977012 0,14881325 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03977012 0,14858217 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03977012 0,14835181 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03977012 0,14812217 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03977012 0,14789323 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03977012 0,147665 ! carnitine transport GO:0015879 10 6 0,000 0,03977012 0,14743747 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03977012 0,14721064 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03977012 0,14698451 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03977012 0,14675908 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03977012 0,14653433 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03977012 0,14631027 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03977012 0,1460869 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03977012 0,14586421 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03977012 0,14564219 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03977012 0,14542085 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03977012 0,14520018 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03977012 0,14498018 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 14 6 0,000 0,03977012 0,14476085 ! response to UV-C GO:0010225 11 6 0,000 0,03977012 0,14454217 ! astrocyte development GO:0014002 15 6 0,000 0,03977012 0,14432416 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03977012 0,14410681 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03977012 0,1438901 ! interaction with symbiont GO:0051702 13 6 0,000 0,03977012 0,14367405 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03977012 0,14345865 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03977012 0,14324389 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03977012 0,14302977 ! response to copper ion GO:0046688 10 6 0,000 0,03977012 0,1428163 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03977012 0,14260346 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03977012 0,14239125 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03977012 0,14217967 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03977012 0,14196872 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03977012 0,1417584 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03977012 0,1415487 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03977012 0,14133961 ! hair follicle maturation GO:0048820 7 6 0,000 0,03977012 0,14113115 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03977012 0,1409233 ! Schwann cell development GO:0014044 15 6 0,000 0,03977012 0,14071606 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03977012 0,14050943 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03977012 0,1403034 ! subpallium development GO:0021544 10 6 0,000 0,03977012 0,14009798 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03977012 0,13989316 ! histone ubiquitination GO:0016574 8 6 0,000 0,03977012 0,13968893 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03977012 0,1394853 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03977012 0,13928227 ! G2 phase GO:0051319 16 6 0,000 0,03977012 0,13907982 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03977012 0,13887797 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03977012 0,13867669 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03977012 0,138476 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03977012 0,13827589 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03977012 0,13807636 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03977012 0,1378774 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03977012 0,13767902 ! receptor internalization GO:0031623 10 6 0,000 0,03977012 0,1374812 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03977012 0,13728396 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03977012 0,13708728 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03977012 0,13689116 ! protein deubiquitination GO:0016579 14 6 0,000 0,03977012 0,1366956 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03977012 0,1365006 ! protein destabilization GO:0031648 9 6 0,000 0,03977012 0,13630615 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03977012 0,13611226 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03977012 0,13591892 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03977012 0,13572613 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03977012 0,13553388 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03977012 0,13534218 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03977012 0,13515101 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03977012 0,13496039 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03977012 0,13477031 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03977012 0,13458076 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03977012 0,13439174 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03977012 0,13420325 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03977012 0,13401529 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03977012 0,13382786 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03977012 0,13364095 ! catecholamine transport GO:0051937 9 6 0,000 0,03977012 0,13345456 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03977012 0,13326869 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03977012 0,13308334 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03977012 0,1328985 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03977012 0,13271417 ! maternal placenta development GO:0001893 12 6 0,000 0,03977012 0,13253036 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03977012 0,13234705 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03977012 0,13216425 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03977012 0,13198196 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03977012 0,13180016 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03977012 0,13161887 ! positive regulation of cyclase activity GO:0031281 103 47 1,000 0,04008218 0,13246939 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,04008218 0,13228767 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,04008218 0,13210646 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,04164335 0,13706415 ! cellular component disassembly GO:0022411 86 48 1,000 0,04164335 0,1368769 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,04164335 0,13669017 ! positive regulation of lyase activity GO:0051349 104 48 1,000 0,04164335 0,13650394 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,04322708 0,14150251 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 0,04322708 0,14131025 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,04322708 0,14111851 GO:0019724|B cell mediated immunity, ! histone modification GO:0016570 91 50 1,000 0,04483299 0,14616284 ! tRNA transcription GO:0009304 14 7 0,000 0,04624373 0,15055806 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04624373 0,15035461 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04624373 0,1501517 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04624373 0,14994934 ! regulation of helicase activity GO:0051095 15 7 0,000 0,04624373 0,14974752 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04624373 0,14954625 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04624373 0,14934551 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04624373 0,14914532 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04624373 0,14894566 ! prostate gland development GO:0030850 13 7 0,000 0,04624373 0,14874653 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04624373 0,14854794 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04624373 0,14834988 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04624373 0,14815234 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04624373 0,14795533 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04624373 0,14775884 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04624373 0,14756288 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04624373 0,14736743 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04624373 0,1471725 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04624373 0,14697808 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04624373 0,14678418 ! glycolipid transport GO:0046836 10 7 0,000 0,04624373 0,14659079 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04624373 0,14639791 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,04624373 0,14620553 ! neuron adhesion GO:0007158 12 7 0,000 0,04624373 0,14601366 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04624373 0,14582229 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04624373 0,14563142 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04624373 0,14544106 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04624373 0,14525119 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04624373 0,14506181 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04624373 0,14487293 ! mRNA stabilization GO:0048255 18 7 0,000 0,04624373 0,14468454 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,04624373 0,14449663 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04624373 0,14430922 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04624373 0,14412229 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04624373 0,14393584 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,04624373 0,14374988 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04624373 0,1435644 ! lipoprotein transport GO:0042953 14 7 0,000 0,04624373 0,14337939 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04624373 0,14319486 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04624373 0,14301081 ! rhythmic behavior GO:0007622 15 7 0,000 0,04624373 0,14282722 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04624373 0,14264411 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04624373 0,14246147 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04624373 0,14227929 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04624373 0,14209758 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04624373 0,14191634 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04624373 0,14173555 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04624373 0,14155523 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04624373 0,14137536 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04624373 0,14119595 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04624373 0,14101699 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04624373 0,14083849 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04624373 0,14066044 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04624373 0,14048284 ! spinal cord patterning GO:0021511 13 7 0,000 0,04624373 0,14030568 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04624373 0,14012898 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04624373 0,13995271 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04624373 0,13977689 ! adrenal gland development GO:0030325 17 7 0,000 0,04624373 0,13960152 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04624373 0,13942658 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04624373 0,13925207 ! ovulation GO:0030728 9 7 0,000 0,04624373 0,13907801 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04624373 0,13890438 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04624373 0,13873118 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04624373 0,13855842 ! microtubule nucleation GO:0007020 20 7 0,000 0,04624373 0,13838608 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04624373 0,13821417 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04624373 0,13804269 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04624373 0,13787163 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04624373 0,137701 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04624373 0,13753079 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04624373 0,137361 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04624373 0,13719162 ! galactose metabolic process GO:0006012 13 7 0,000 0,04624373 0,13702267 ! vesicle fusion GO:0006906 17 7 0,000 0,04624373 0,13685413 ! response to dietary excess GO:0002021 8 7 0,000 0,04624373 0,136686 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04624373 0,13651829 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04624373 0,13635099 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04624373 0,1361841 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04624373 0,13601761 ! organ growth GO:0035265 15 7 0,000 0,04624373 0,13585154 ! purine salvage GO:0043101 10 7 0,000 0,04624373 0,13568586 ! nucleoside transport GO:0015858 8 7 0,000 0,04624373 0,13552059 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04624373 0,13535573 ! parturition GO:0007567 14 7 0,000 0,04624373 0,13519126 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04624373 0,13502719 ! rRNA modification GO:0000154 14 7 0,000 0,04624373 0,13486352 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04624373 0,13470025 ! spindle checkpoint GO:0031577 15 7 0,000 0,04624373 0,13453737 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04624373 0,13437489 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04624373 0,1342128 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04624373 0,13405109 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04624373 0,13388978 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04624373 0,13372886 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04624373 0,13356832 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,04624373 0,13340816 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04624373 0,13324839 ! fibrinolysis GO:0042730 10 7 0,000 0,04624373 0,133089 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,04624373 0,13293 ! eating behavior GO:0042755 7 7 0,000 0,04624373 0,13277137 ! B cell lineage commitment GO:0002326 21 7 0,000 0,04624373 0,13261312 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04624373 0,13245525 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04624373 0,13229775 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04624373 0,13214063 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04624373 0,13198388 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04624373 0,1318275 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04624373 0,13167149 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04624373 0,13151585 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04624373 0,13136058 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04624373 0,13120567 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04624373 0,13105113 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04624373 0,13089695 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04624373 0,13074313 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04624373 0,13058968 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04624373 0,13043659 ! regulation of meiosis GO:0040020 12 7 0,000 0,04624373 0,13028385 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04624373 0,13013147 ! T cell lineage commitment GO:0002360 16 7 0,000 0,04624373 0,12997945 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04624373 0,12982778 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04624373 0,12967647 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04624373 0,1295255 ! transcription termination GO:0006353 13 7 0,000 0,04624373 0,12937489 ! response to tumor cell GO:0002347 13 7 0,000 0,04624373 0,12922463 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,04624373 0,12907472 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04624373 0,12892515 ! anaphase GO:0051322 17 7 0,000 0,04624373 0,12877593 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04624373 0,12862706 ! axonal fasciculation GO:0007413 18 7 0,000 0,04624373 0,12847853 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04624373 0,12833034 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04624373 0,1281825 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,04624373 0,12803499 ! diuresis GO:0030146 12 7 0,000 0,04624373 0,12788783 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04624373 0,127741 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04624373 0,1275945 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04624373 0,12744835 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04624373 0,12730253 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04624373 0,12715704 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04624373 0,12701188 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04624373 0,12686706 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04624373 0,12672256 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04624373 0,12657839 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04624373 0,12643455 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04624373 0,12629104 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04624373 0,12614785 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04624373 0,12600499 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04624373 0,12586245 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04624373 0,12572023 ! adult feeding behavior GO:0008343 9 7 0,000 0,04624373 0,12557834 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04624373 0,12543676 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04624373 0,1252955 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04624373 0,12515456 ! muscle adaptation GO:0043500 14 7 0,000 0,04624373 0,12501394 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04624373 0,12487363 ! retina homeostasis GO:0001895 12 7 0,000 0,04624373 0,12473364 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04624373 0,12459396 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04624373 0,12445459 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04624373 0,12431554 ! protein prenylation GO:0018342 18 7 0,000 0,04624373 0,12417679 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04624373 0,12403836 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04624373 0,12390023 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04624373 0,12376241 ! cellular amino acid biosynthetic process GO:0008652 75 51 1,000 0,04646073 0,12420501 ! chromatin remodeling GO:0006338 109 51 1,000 0,04646073 0,12406716 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,04646073 0,12392961 ! positive regulation of growth GO:0045927 90 52 1,000 0,04810992 0,12818656 ! covalent chromatin modification GO:0016569 101 52 1,000 0,04810992 0,12804476 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,0497802 0,13234384 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,0497802 0,13219776 ! response to UV GO:0009411 104 53 1,000 0,0497802 0,13205201 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,05147123 0,13638742 ! glutamine family amino acid metabolic process GO:0009064 78 54 1,000 0,05147123 0,13623738 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0526739 0,13926748 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0526739 0,13911461 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,0526739 0,13896207 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0526739 0,13880986 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0526739 0,13865799 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0526739 0,13850645 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0526739 0,13835525 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0526739 0,13820437 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0526739 0,13805382 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0526739 0,1379036 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0526739 0,1377537 ! meiotic prophase I GO:0007128 13 8 0,000 0,0526739 0,13760413 ! oligopeptide transport GO:0006857 15 8 0,000 0,0526739 0,13745489 ! signal peptide processing GO:0006465 12 8 0,000 0,0526739 0,13730596 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0526739 0,13715736 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0526739 0,13700909 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0526739 0,13686113 ! succinate metabolic process GO:0006105 14 8 0,000 0,0526739 0,13671349 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0526739 0,13656617 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,0526739 0,13641917 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0526739 0,13627248 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0526739 0,13612611 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0526739 0,13598005 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0526739 0,1358343 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0526739 0,13568887 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0526739 0,13554375 ! reflex GO:0060004 16 8 0,000 0,0526739 0,13539894 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0526739 0,13525443 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0526739 0,13511024 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0526739 0,13496635 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0526739 0,13482277 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0526739 0,1346795 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0526739 0,13453652 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0526739 0,13439385 ! pigment granule organization GO:0048753 16 8 0,000 0,0526739 0,13425149 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0526739 0,13410942 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0526739 0,13396766 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0526739 0,13382619 ! histidine metabolic process GO:0006547 16 8 0,000 0,0526739 0,13368503 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0526739 0,13354416 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0526739 0,13340358 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0526739 0,13326331 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0526739 0,13312332 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,0526739 0,13298364 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0526739 0,13284424 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,0526739 0,13270514 ! melanin metabolic process GO:0006582 15 8 0,000 0,0526739 0,13256632 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0526739 0,1324278 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0526739 0,13228957 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0526739 0,13215162 ! macrophage activation GO:0042116 12 8 0,000 0,0526739 0,13201396 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0526739 0,13187659 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0526739 0,13173951 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0526739 0,13160271 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0526739 0,13146619 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0526739 0,13132995 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0526739 0,131194 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0526739 0,13105833 ! osteoblast development GO:0002076 16 8 0,000 0,0526739 0,13092294 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0526739 0,13078783 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0526739 0,130653 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0526739 0,13051844 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0526739 0,13038416 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,0526739 0,13025016 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0526739 0,13011643 ! response to UV-B GO:0010224 16 8 0,000 0,0526739 0,12998298 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0526739 0,1298498 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0526739 0,12971689 ! intermediate filament organization GO:0045109 12 8 0,000 0,0526739 0,12958426 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0526739 0,12945189 ! cellular extravasation GO:0045123 12 8 0,000 0,0526739 0,1293198 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0526739 0,12918798 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0526739 0,12905642 ! response to antibiotic GO:0046677 11 8 0,000 0,0526739 0,12892513 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0526739 0,12879411 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0526739 0,12866336 ! DNA topological change GO:0006265 12 8 0,000 0,0526739 0,12853287 ! response to tropane GO:0014073 15 8 0,000 0,0526739 0,12840264 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0526739 0,12827268 ! melanosome transport GO:0032402 13 8 0,000 0,0526739 0,12814298 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0526739 0,12801354 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0526739 0,12788436 ! mast cell activation GO:0045576 14 8 0,000 0,0526739 0,12775545 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0526739 0,12762679 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0526739 0,1274984 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0526739 0,12737026 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0526739 0,12724237 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0526739 0,12711475 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0526739 0,12698738 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0526739 0,12686027 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0526739 0,12673341 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0526739 0,1266068 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0526739 0,12648044 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0526739 0,12635434 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0526739 0,12622849 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0526739 0,12610289 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0526739 0,12597754 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0526739 0,12585244 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0526739 0,12572758 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0526739 0,12560298 ! hormone catabolic process GO:0042447 17 8 0,000 0,0526739 0,12547862 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0526739 0,12535451 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0526739 0,12523064 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0526739 0,12510701 ! ATP catabolic process GO:0006200 11 8 0,000 0,0526739 0,12498363 ! blastocyst growth GO:0001832 19 8 0,000 0,0526739 0,1248605 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0526739 0,1247376 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0526739 0,12461495 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0526739 0,12449254 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0526739 0,12437037 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0526739 0,12424844 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0526739 0,12412674 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0526739 0,12400529 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0526739 0,12388407 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0526739 0,12376309 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0526739 0,12364235 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0526739 0,12352184 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0526739 0,12340156 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0526739 0,12328152 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0526739 0,12316172 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0526739 0,12304214 ! glucose catabolic process GO:0006007 82 55 1,000 0,05318264 0,12411002 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,05318264 0,12398976 ! aging GO:0007568 103 55 1,000 0,05318264 0,12386973 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,05318264 0,12374993 ! regulation of actin filament length GO:0030832 105 56 1,000 0,05491409 0,12765536 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,05491409 0,12753214 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,05491409 0,12740916 ! lipid modification GO:0030258 97 57 1,000 0,05666523 0,13134542 ! adult behavior GO:0030534 99 58 1,000 0,05843573 0,13531892 ! regulation of developmental growth GO:0048638 15 9 0,000 0,05906093 0,1366352 ! axon extension GO:0048675 15 9 0,000 0,05906093 0,13650395 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05906093 0,13637294 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,05906093 0,13624219 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05906093 0,13611169 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05906093 0,13598144 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05906093 0,13585144 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05906093 0,13572169 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05906093 0,13559218 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05906093 0,13546292 ! phosphate transport GO:0006817 19 9 0,000 0,05906093 0,13533391 ! reproductive behavior GO:0019098 19 9 0,000 0,05906093 0,13520515 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05906093 0,13507662 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05906093 0,13494835 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05906093 0,13482031 ! RNA methylation GO:0001510 15 9 0,000 0,05906093 0,13469252 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05906093 0,13456497 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,05906093 0,13443766 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05906093 0,13431059 ! artery development GO:0060840 24 9 0,000 0,05906093 0,13418377 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05906093 0,13405718 ! regulation of glycolysis GO:0006110 21 9 0,000 0,05906093 0,13393083 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05906093 0,13380472 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05906093 0,13367884 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05906093 0,1335532 ! chemosensory behavior GO:0007635 20 9 0,000 0,05906093 0,1334278 ! microtubule bundle formation GO:0001578 21 9 0,000 0,05906093 0,13330263 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,05906093 0,1331777 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05906093 0,133053 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05906093 0,13292854 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05906093 0,13280431 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05906093 0,13268031 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05906093 0,13255654 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05906093 0,132433 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05906093 0,13230969 ! protein targeting to ER GO:0045047 22 9 0,000 0,05906093 0,13218661 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05906093 0,13206376 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05906093 0,13194114 ! T cell selection GO:0045058 23 9 0,000 0,05906093 0,13181875 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05906093 0,13169658 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05906093 0,13157464 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05906093 0,13145292 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05906093 0,13133143 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05906093 0,13121016 ! mannose metabolic process GO:0006013 13 9 0,000 0,05906093 0,13108912 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05906093 0,1309683 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05906093 0,13084771 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05906093 0,13072733 ! receptor clustering GO:0043113 18 9 0,000 0,05906093 0,13060718 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05906093 0,13048724 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05906093 0,13036753 ! ruffle organization GO:0031529 15 9 0,000 0,05906093 0,13024804 ! retinol metabolic process GO:0042572 18 9 0,000 0,05906093 0,13012876 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05906093 0,13000971 ! behavioral fear response GO:0001662 22 9 0,000 0,05906093 0,12989087 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05906093 0,12977225 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05906093 0,12965384 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05906093 0,12953565 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,05906093 0,12941768 ! protein heterooligomerization GO:0051291 16 9 0,000 0,05906093 0,12929992 ! oligodendrocyte development GO:0014003 10 9 0,000 0,05906093 0,12918237 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05906093 0,12906504 ! segment specification GO:0007379 13 9 0,000 0,05906093 0,12894792 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05906093 0,12883101 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05906093 0,12871432 ! response to amine stimulus GO:0014075 13 9 0,000 0,05906093 0,12859784 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05906093 0,12848156 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05906093 0,1283655 ! erythrocyte development GO:0048821 15 9 0,000 0,05906093 0,12824965 ! gas homeostasis GO:0033483 16 9 0,000 0,05906093 0,128134 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05906093 0,12801857 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05906093 0,12790334 ! renal water homeostasis GO:0003091 14 9 0,000 0,05906093 0,12778832 ! postreplication repair GO:0006301 22 9 0,000 0,05906093 0,1276735 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05906093 0,12755889 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05906093 0,12744449 ! icosanoid secretion GO:0032309 15 9 0,000 0,05906093 0,12733029 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05906093 0,1272163 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05906093 0,12710251 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05906093 0,12698893 ! regulation of cell division GO:0051302 15 9 0,000 0,05906093 0,12687554 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05906093 0,12676236 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05906093 0,12664938 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05906093 0,12653661 ! sterol catabolic process GO:0016127 11 9 0,000 0,05906093 0,12642403 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05906093 0,12631165 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05906093 0,12619947 ! S phase GO:0051320 9 9 0,000 0,05906093 0,1260875 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05906093 0,12597572 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05906093 0,12586413 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05906093 0,12575275 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05906093 0,12564156 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05906093 0,12553057 ! purine base metabolic process GO:0006144 21 9 0,000 0,05906093 0,12541978 ! pigment granule transport GO:0051904 17 9 0,000 0,05906093 0,12530918 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05906093 0,12519877 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,05906093 0,12508856 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05906093 0,12497855 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05906093 0,12486872 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05906093 0,12475909 ! mitochondrion localization GO:0051646 15 9 0,000 0,05906093 0,12464966 ! regulation of cellular component size GO:0032535 109 59 1,000 0,06022524 0,12699555 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,06022524 0,12688434 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,06022524 0,12677333 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,06022524 0,12666252 ! regulation of heart contraction GO:0008016 110 60 1,000 0,06203343 0,13035146 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,06203343 0,13023772 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 0,06203343 0,13012417 ! kidney development GO:0001822 122 60 1,000 0,06203343 0,13001082 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,06385997 0,13372244 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,06540512 0,13683888 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06540512 0,13671999 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,06540512 0,13660131 ! synapsis GO:0007129 13 10 0,000 0,06540512 0,13648284 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,06540512 0,13636457 ! N-glycan processing GO:0006491 20 10 0,000 0,06540512 0,1362465 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,06540512 0,13612864 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,06540512 0,13601099 ! social behavior GO:0035176 24 10 0,000 0,06540512 0,13589353 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,06540512 0,13577628 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,06540512 0,13565923 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,06540512 0,13554239 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,06540512 0,13542574 ! androgen metabolic process GO:0008209 17 10 0,000 0,06540512 0,1353093 ! phospholipid efflux GO:0033700 16 10 0,000 0,06540512 0,13519305 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,06540512 0,135077 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,06540512 0,13496116 ! lung alveolus development GO:0048286 26 10 0,000 0,06540512 0,13484551 ! pathogenesis GO:0009405 13 10 0,000 0,06540512 0,13473006 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06540512 0,13461481 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,06540512 0,13449975 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,06540512 0,13438489 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,06540512 0,13427023 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,06540512 0,13415576 ! endoderm development GO:0007492 16 10 0,000 0,06540512 0,13404149 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,06540512 0,13392741 ! arginine catabolic process GO:0006527 13 10 0,000 0,06540512 0,13381353 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06540512 0,13369984 ! proline metabolic process GO:0006560 13 10 0,000 0,06540512 0,13358634 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,06540512 0,13347304 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,06540512 0,13335992 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,06540512 0,133247 ! V(D)J recombination GO:0033151 28 10 0,000 0,06540512 0,13313427 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06540512 0,13302173 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,06540512 0,13290938 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,06540512 0,13279722 ! B cell proliferation GO:0042100 18 10 0,000 0,06540512 0,13268525 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,06540512 0,13257347 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,06540512 0,13246188 ! multicellular organism growth GO:0035264 18 10 0,000 0,06540512 0,13235047 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,06540512 0,13223925 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,06540512 0,13212822 ! epithelial cell development GO:0002064 20 10 0,000 0,06540512 0,13201737 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,06540512 0,13190671 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06540512 0,13179624 ! macroautophagy GO:0016236 17 10 0,000 0,06540512 0,13168595 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,06540512 0,13157584 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,06540512 0,13146592 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,06540512 0,13135619 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,06540512 0,13124663 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,06540512 0,13113726 ! copper ion homeostasis GO:0055070 13 10 0,000 0,06540512 0,13102807 ! regulation of bone resorption GO:0045124 25 10 0,000 0,06540512 0,13091906 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,06540512 0,13081023 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,06540512 0,13070159 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,06540512 0,13059312 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,06540512 0,13048483 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,06540512 0,13037673 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,06540512 0,1302688 ! blastoderm segmentation GO:0007350 18 10 0,000 0,06540512 0,13016105 ! response to dsRNA GO:0043331 20 10 0,000 0,06540512 0,13005348 ! DNA ligation GO:0006266 19 10 0,000 0,06540512 0,12994609 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06540512 0,12983887 ! melanosome localization GO:0032400 16 10 0,000 0,06540512 0,12973183 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,06540512 0,12962497 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,06540512 0,12951828 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,06540512 0,12941177 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06540512 0,12930543 ! mRNA cleavage GO:0006379 17 10 0,000 0,06540512 0,12919927 ! protein sumoylation GO:0016925 15 10 0,000 0,06540512 0,12909328 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06540512 0,12898747 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06540512 0,12888183 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06540512 0,12877636 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,06540512 0,12867106 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,06540512 0,12856594 ! salivary gland development GO:0007431 27 10 0,000 0,06540512 0,12846099 ! prophase GO:0051324 15 10 0,000 0,06540512 0,12835621 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06540512 0,1282516 ! apical protein localization GO:0045176 15 10 0,000 0,06540512 0,12814716 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,06540512 0,12804289 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,06540512 0,12793879 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,06540512 0,12783486 ! midbrain development GO:0030901 13 10 0,000 0,06540512 0,1277311 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06540512 0,1276275 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,06540512 0,12752408 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,06540512 0,12742082 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06540512 0,12731773 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06540512 0,1272148 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,06540512 0,12711204 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,06540512 0,12700945 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,06540512 0,12690702 ! oocyte development GO:0048599 17 10 0,000 0,06540512 0,12680476 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06540512 0,12670267 ! blastocyst formation GO:0001825 17 10 0,000 0,06540512 0,12660073 ! cerebellar cortex development GO:0021695 15 10 0,000 0,06540512 0,12649896 ! activation of innate immune response GO:0002218 12 10 0,000 0,06540512 0,12639736 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,06540512 0,12629592 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,06540512 0,12619464 ! response to nicotine GO:0035094 20 10 0,000 0,06540512 0,12609352 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,06540512 0,12599256 ! localization within membrane GO:0051668 20 10 0,000 0,06540512 0,12589177 ! water-soluble vitamin metabolic process GO:0006767 95 62 1,000 0,06570453 0,12636699 ! cell redox homeostasis GO:0045454 102 64 1,000 0,06944644 0,13345698 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,06944644 0,13335047 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,06944644 0,13324413 GO:0048609|reproductive process in a multicellular organism, ! negative regulation of muscle development GO:0048635 20 11 0,000 0,07170673 0,13747123 ! respiratory burst GO:0045730 17 11 0,000 0,07170673 0,13736178 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,07170673 0,13725251 ! neuron fate specification GO:0048665 17 11 0,000 0,07170673 0,1371434 ! telencephalon cell migration GO:0022029 20 11 0,000 0,07170673 0,13703447 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,07170673 0,13692571 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,07170673 0,13681713 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,07170673 0,13670872 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,07170673 0,13660047 ! response to pain GO:0048265 24 11 0,000 0,07170673 0,1364924 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,07170673 0,13638451 ! T cell proliferation GO:0042098 26 11 0,000 0,07170673 0,13627678 ! blood vessel remodeling GO:0001974 29 11 0,000 0,07170673 0,13616922 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,07170673 0,13606183 ! bone resorption GO:0045453 16 11 0,000 0,07170673 0,13595461 ! ventral spinal cord development GO:0021517 21 11 0,000 0,07170673 0,13584756 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,07170673 0,13574068 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,07170673 0,13563396 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,07170673 0,13552741 ! melanocyte differentiation GO:0030318 21 11 0,000 0,07170673 0,13542104 GO:0050931|pigment cell differentiation, ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,07170673 0,13531482 GO:0010833|telomere maintenance via telomere lengthening, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,07170673 0,13520878 ! lipid digestion GO:0044241 18 11 0,000 0,07170673 0,1351029 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,07170673 0,13499718 ! UV protection GO:0009650 19 11 0,000 0,07170673 0,13489163 ! adult heart development GO:0007512 14 11 0,000 0,07170673 0,13478625 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,07170673 0,13468103 ! temperature homeostasis GO:0001659 17 11 0,000 0,07170673 0,13457597 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,07170673 0,13447108 ! negative regulation of ossification GO:0030279 26 11 0,000 0,07170673 0,13436635 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,07170673 0,13426179 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,07170673 0,13415739 ! regulation of organ growth GO:0046620 13 11 0,000 0,07170673 0,13405315 ! pigment granule localization GO:0051875 20 11 0,000 0,07170673 0,13394907 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,07170673 0,13384515 ! vasoconstriction GO:0042310 18 11 0,000 0,07170673 0,13374139 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,07170673 0,1336378 ! embryonic axis specification GO:0000578 18 11 0,000 0,07170673 0,13353436 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,07170673 0,13343109 ! snRNA metabolic process GO:0016073 24 11 0,000 0,07170673 0,13332797 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,07170673 0,13322502 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,07170673 0,13312222 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,07170673 0,13301958 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,07170673 0,1329171 ! zymogen activation GO:0031638 15 11 0,000 0,07170673 0,13281478 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,07170673 0,13271261 ! neuroblast proliferation GO:0007405 24 11 0,000 0,07170673 0,13261061 ! nucleosome positioning GO:0016584 15 11 0,000 0,07170673 0,13250875 ! regulation of isotype switching GO:0045191 22 11 0,000 0,07170673 0,13240706 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,07170673 0,13230552 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,07170673 0,13220414 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,07170673 0,13210291 ! acid secretion GO:0046717 18 11 0,000 0,07170673 0,13200184 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,07170673 0,13190092 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,07170673 0,13180015 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,07170673 0,13169954 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,07170673 0,13159908 ! oocyte differentiation GO:0009994 18 11 0,000 0,07170673 0,13149878 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,07170673 0,13139863 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,07170673 0,13129863 ! cholesterol efflux GO:0033344 19 11 0,000 0,07170673 0,13119878 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,07170673 0,13109909 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,07170673 0,13099954 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,07170673 0,13090015 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,07170673 0,13080091 ! embryonic gut development GO:0048566 15 11 0,000 0,07170673 0,13070182 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,07170673 0,13060288 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,07170673 0,13050408 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,07170673 0,13040544 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,07170673 0,13030695 ! defense response to fungus GO:0050832 13 11 0,000 0,07170673 0,1302086 ! developmental induction GO:0031128 19 11 0,000 0,07170673 0,13011041 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,07170673 0,13001236 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,07170673 0,12991446 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,07170673 0,1298167 ! sequestering of metal ion GO:0051238 14 11 0,000 0,07170673 0,1297191 ! lamellipodium assembly GO:0030032 20 11 0,000 0,07170673 0,12962164 ! regulation of synapse organization GO:0050807 17 11 0,000 0,07170673 0,12952432 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,07325662 0,13222462 ! secondary metabolic process GO:0019748 116 66 1,000 0,07325662 0,1321255 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,07518652 0,1355047 ! lung development GO:0030324 144 67 1,000 0,07518652 0,13540327 ! chromosome segregation GO:0007059 113 67 1,000 0,07518652 0,135302 ! hexose catabolic process GO:0019320 104 67 1,000 0,07518652 0,13520087 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,07518652 0,1350999 ! adaptive immune response GO:0002250 119 67 1,000 0,07518652 0,13499908 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 1,000 0,07518652 0,13489841 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,07713256 0,13828684 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 130 68 1,000 0,07713256 0,13818388 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,07713256 0,13808106 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,07796607 0,13946941 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,07796607 0,13936579 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,07796607 0,13926233 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,07796607 0,13915902 ! virus-host interaction GO:0019048 29 12 0,000 0,07796607 0,13905586 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,07796607 0,13895286 ! cartilage condensation GO:0001502 20 12 0,000 0,07796607 0,13885001 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,07796607 0,13874731 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,07796607 0,13864476 ! protein complex disassembly GO:0043241 27 12 0,000 0,07796607 0,13854236 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,07796607 0,13844012 ! hippocampus development GO:0021766 26 12 0,000 0,07796607 0,13833802 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,07796607 0,13823608 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,07796607 0,13813428 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07796607 0,13803264 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,07796607 0,13793115 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,07796607 0,1378298 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,07796607 0,1377286 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,07796607 0,13762756 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,07796607 0,13752666 ! drug transport GO:0015893 16 12 0,000 0,07796607 0,1374259 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,07796607 0,1373253 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,07796607 0,13722484 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,07796607 0,13712453 ! polyamine metabolic process GO:0006595 17 12 0,000 0,07796607 0,13702437 ! focal adhesion formation GO:0048041 35 12 0,000 0,07796607 0,13692435 ! mitotic spindle organization GO:0007052 21 12 0,000 0,07796607 0,13682448 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,07796607 0,13672475 ! forebrain cell migration GO:0021885 21 12 0,000 0,07796607 0,13662517 ! asymmetric protein localization GO:0008105 20 12 0,000 0,07796607 0,13652573 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,07796607 0,13642644 ! fear response GO:0042596 26 12 0,000 0,07796607 0,1363273 ! monoamine transport GO:0015844 18 12 0,000 0,07796607 0,13622829 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07796607 0,13612943 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,07796607 0,13603072 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,07796607 0,13593214 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,07796607 0,13583371 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07796607 0,13573543 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,07796607 0,13563728 ! protein homotetramerization GO:0051289 21 12 0,000 0,07796607 0,13553928 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,07796607 0,13544141 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,07796607 0,13534369 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,07796607 0,13524611 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,07796607 0,13514867 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07796607 0,13505137 ! cranial nerve development GO:0021545 20 12 0,000 0,07796607 0,13495421 ! fucose catabolic process GO:0019317 22 12 0,000 0,07796607 0,1348572 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,07796607 0,13476031 ! histone methylation GO:0016571 26 12 0,000 0,07796607 0,13466357 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,07796607 0,13456697 ! autonomic nervous system development GO:0048483 24 12 0,000 0,07796607 0,13447051 ! gland morphogenesis GO:0022612 29 12 0,000 0,07796607 0,13437418 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,07796607 0,13427799 ! T cell homeostasis GO:0043029 25 12 0,000 0,07796607 0,13418194 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,07796607 0,13408603 ! spleen development GO:0048536 22 12 0,000 0,07796607 0,13399026 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,07796607 0,13389462 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,07796607 0,13379911 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,07796607 0,13370375 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,07796607 0,13360852 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,07796607 0,13351342 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,07796607 0,13341846 ! response to cold GO:0009409 17 12 0,000 0,07796607 0,13332364 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,07796607 0,13322895 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,07796607 0,13313439 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,07909444 0,1349654 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,07909444 0,13486975 ! urogenital system development GO:0001655 137 69 1,000 0,07909444 0,13477423 ! coenzyme biosynthetic process GO:0009108 102 69 1,000 0,07909444 0,13467885 ! antigen processing and presentation GO:0019882 104 69 1,000 0,07909444 0,1345836 ! respiratory tube development GO:0030323 150 70 1,000 0,08107185 0,13785079 ! humoral immune response GO:0006959 109 71 1,000 0,0830645 0,14113925 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,0830645 0,14103965 ! regulation of immune effector process GO:0002697 137 71 1,000 0,0830645 0,14094018 ! cGMP metabolic process GO:0046068 18 13 0,000 0,0841834 0,14273803 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,0841834 0,14263751 ! regulation of chemokine production GO:0032642 18 13 0,000 0,0841834 0,14253713 ! peroxisomal transport GO:0043574 24 13 0,000 0,0841834 0,1424369 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,0841834 0,1423368 ! lipid localization GO:0010876 28 13 0,000 0,0841834 0,14223685 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,0841834 0,14213703 ! organelle fusion GO:0048284 32 13 0,000 0,0841834 0,14203735 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,0841834 0,14193782 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,0841834 0,14183842 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,0841834 0,14173917 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,0841834 0,14164005 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,0841834 0,14154107 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,0841834 0,14144223 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,0841834 0,14134352 ! methionine metabolic process GO:0006555 27 13 0,000 0,0841834 0,14124496 ! plasma membrane organization GO:0007009 24 13 0,000 0,0841834 0,14114653 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,0841834 0,14104824 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,0841834 0,14095008 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,0841834 0,14085206 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,0841834 0,14075418 ! response to X-ray GO:0010165 25 13 0,000 0,0841834 0,14065644 ! cytokine metabolic process GO:0042107 22 13 0,000 0,0841834 0,14055883 ! exocrine system development GO:0035272 32 13 0,000 0,0841834 0,14046135 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,0841834 0,14036401 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,0841834 0,14026681 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,0841834 0,14016974 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,0841834 0,1400728 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,0841834 0,139976 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,0841834 0,13987933 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,0841834 0,13978279 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,0841834 0,13968639 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,0841834 0,13959012 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,0841834 0,13949399 ! regulation of cellular pH GO:0030641 22 13 0,000 0,0841834 0,13939798 ! ribosome assembly GO:0042255 17 13 0,000 0,0841834 0,13930211 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,0841834 0,13920637 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,0841834 0,13911076 ! chromatin silencing GO:0006342 26 13 0,000 0,0841834 0,13901528 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,0841834 0,13891994 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,0841834 0,13882472 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,0841834 0,13872964 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,0841834 0,13863468 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,0841834 0,13853985 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,0841834 0,13844516 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,0841834 0,13835059 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,0841834 0,13825616 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,0841834 0,13816185 ! embryonic placenta development GO:0001892 23 13 0,000 0,0841834 0,13806767 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,0841834 0,13797362 ! insulin secretion GO:0030073 23 13 0,000 0,0841834 0,13787969 ! actin filament polymerization GO:0030041 24 13 0,000 0,0841834 0,1377859 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,0841834 0,13769223 ! acrosome reaction GO:0007340 18 13 0,000 0,0841834 0,13759869 ! acute inflammatory response GO:0002526 113 72 1,000 0,08507209 0,13895686 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,08507209 0,13886258 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,08507209 0,13876844 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,08507209 0,13867442 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,08507209 0,13858053 ! respiratory system development GO:0060541 153 72 1,000 0,08507209 0,13848677 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,08913096 0,144996 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,08913096 0,14489803 ! rRNA transcription GO:0009303 25 14 0,000 0,09035902 0,14679527 ! reproductive cellular process GO:0048610 20 14 0,000 0,09035902 0,14669622 ! tRNA modification GO:0006400 20 14 0,000 0,09035902 0,1465973 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,09035902 0,14649852 ! regulation of S phase GO:0033261 23 14 0,000 0,09035902 0,14639987 ! water transport GO:0006833 21 14 0,000 0,09035902 0,14630135 GO:0042044|fluid transport, ! non-recombinational repair GO:0000726 25 14 0,000 0,09035902 0,14620296 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,09035902 0,14610471 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,09035902 0,14600658 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,09035902 0,14590859 ! RNA polyadenylation GO:0043631 30 14 0,000 0,09035902 0,14581073 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,09035902 0,145713 ! palate development GO:0060021 31 14 0,000 0,09035902 0,14561541 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,09035902 0,14551794 ! regulated secretory pathway GO:0045055 23 14 0,000 0,09035902 0,1454206 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,09035902 0,1453234 ! arginine metabolic process GO:0006525 17 14 0,000 0,09035902 0,14522632 ! regulation of heart rate GO:0002027 24 14 0,000 0,09035902 0,14512937 ! organic alcohol transport GO:0015850 29 14 0,000 0,09035902 0,14503256 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,09035902 0,14493587 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,09035902 0,14483931 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,09035902 0,14474288 ! neutral amino acid transport GO:0015804 26 14 0,000 0,09035902 0,14464657 ! L-amino acid transport GO:0015807 30 14 0,000 0,09035902 0,1445504 ! bone mineralization GO:0030282 17 14 0,000 0,09035902 0,14445435 ! stem cell development GO:0048864 43 14 0,000 0,09035902 0,14435843 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,09035902 0,14426264 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,09035902 0,14416698 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,09035902 0,14407144 ! cerebellum development GO:0021549 21 14 0,000 0,09035902 0,14397603 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,09035902 0,14388074 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,09035902 0,14378558 ! response to gamma radiation GO:0010332 28 14 0,000 0,09035902 0,14369055 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,09035902 0,14359564 ! cofactor transport GO:0051181 26 14 0,000 0,09035902 0,14350086 ! NADP metabolic process GO:0006739 24 14 0,000 0,09035902 0,1434062 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,09035902 0,14331167 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,09035902 0,14321726 ! intestinal absorption GO:0050892 25 14 0,000 0,09035902 0,14312298 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,09035902 0,14302882 ! oxygen transport GO:0015671 21 14 0,000 0,09035902 0,14293478 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,09035902 0,14284087 ! male genitalia development GO:0030539 24 14 0,000 0,09035902 0,14274708 ! regulation of RNA stability GO:0043487 32 14 0,000 0,09035902 0,14265341 ! regulation of axon extension GO:0030516 37 14 0,000 0,09035902 0,14255987 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,09035902 0,14246645 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,09035902 0,14237315 ! monosaccharide catabolic process GO:0046365 115 76 1,000 0,09324618 0,14682612 ! regulation of catabolic process GO:0009894 161 76 1,000 0,09324618 0,14673009 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,09532422 0,14990201 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,09532422 0,1498041 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0964932 0,15154219 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0964932 0,15144333 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,0964932 0,15134461 ! superoxide anion generation GO:0042554 20 15 0,000 0,0964932 0,15124601 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,0964932 0,15114755 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0964932 0,15104921 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0964932 0,150951 ! copper ion transport GO:0006825 20 15 0,000 0,0964932 0,15085291 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0964932 0,15075496 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0964932 0,15065713 ! sulfate transport GO:0008272 23 15 0,000 0,0964932 0,15055942 ! response to cAMP GO:0051591 22 15 0,000 0,0964932 0,15046185 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0964932 0,1503644 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0964932 0,15026708 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0964932 0,15016988 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0964932 0,15007281 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0964932 0,14997586 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0964932 0,14987904 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0964932 0,14978234 ! pituitary gland development GO:0021983 29 15 0,000 0,0964932 0,14968577 ! vesicle coating GO:0006901 33 15 0,000 0,0964932 0,14958932 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,0964932 0,149493 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0964932 0,1493968 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,0964932 0,14930073 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0964932 0,14920478 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,0964932 0,14910895 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0964932 0,14901324 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0964932 0,14891766 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0964932 0,1488222 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0964932 0,14872686 ! histone deacetylation GO:0016575 20 15 0,000 0,0964932 0,14863165 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0964932 0,14853655 ! tissue regeneration GO:0042246 26 15 0,000 0,0964932 0,14844158 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0964932 0,14834673 ! water homeostasis GO:0030104 27 15 0,000 0,0964932 0,148252 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0964932 0,14815739 ! muscle maintenance GO:0046716 26 15 0,000 0,0964932 0,1480629 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0964932 0,14796853 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0964932 0,14787429 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0964932 0,14778016 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0964932 0,14768615 ! cell killing GO:0001906 29 15 0,000 0,0964932 0,14759226 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,0964932 0,14749849 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0964932 0,14740485 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0964932 0,14731131 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0964932 0,1472179 ! peptide hormone processing GO:0016486 23 15 0,000 0,0964932 0,14712461 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,0995198 0,15164322 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,0995198 0,15154724 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,0995198 0,15145138 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,1016368 0,15457531 ! protein import into nucleus GO:0006606 158 80 1,000 0,1016368 0,15447766 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,10258621 0,15582224 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,10258621 0,15572392 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,10258621 0,15562574 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,10258621 0,15552768 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,10258621 0,15542974 ! bone remodeling GO:0046849 27 16 0,000 0,10258621 0,15533192 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,10258621 0,15523423 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,10258621 0,15513666 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,10258621 0,15503921 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,10258621 0,15494188 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,10258621 0,15484468 ! startle response GO:0001964 28 16 0,000 0,10258621 0,1547476 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,10258621 0,15465064 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,10258621 0,1545538 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,10258621 0,15445708 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,10258621 0,15436049 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,10258621 0,15426401 ! protein polyubiquitination GO:0000209 34 16 0,000 0,10258621 0,15416766 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,10258621 0,15407142 ! response to osmotic stress GO:0006970 25 16 0,000 0,10258621 0,15397531 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,10258621 0,15387931 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,10258621 0,15378344 ! fructose metabolic process GO:0006000 25 16 0,000 0,10258621 0,15368768 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,10258621 0,15359205 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,10258621 0,15349653 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,10258621 0,15340113 ! axon cargo transport GO:0008088 43 16 0,000 0,10258621 0,15330585 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,10258621 0,15321069 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,10258621 0,15311565 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,10258621 0,15302072 ! DNA replication initiation GO:0006270 27 16 0,000 0,10258621 0,15292591 ! neuron recognition GO:0008038 35 16 0,000 0,10258621 0,15283122 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,10258621 0,15273665 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,10258621 0,15264219 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,10258621 0,15254785 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,10258621 0,15245363 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,10258621 0,15235952 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,10258621 0,15226553 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,10258621 0,15217165 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,10258621 0,15207789 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,10258621 0,15198425 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,10258621 0,15189072 ! defense response to virus GO:0051607 37 16 0,000 0,10258621 0,15179731 ! response to hypoxia GO:0001666 171 81 1,000 0,10376625 0,15344904 ! nuclear import GO:0051170 161 81 1,000 0,10376625 0,15335479 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,10590789 0,15642381 ! response to nutrient GO:0007584 125 82 1,000 0,10590789 0,15632784 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,10590789 0,15623199 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,10590789 0,15613626 ! response to oxygen levels GO:0070482 176 83 1,000 0,10806146 0,15921364 ! regulation of lyase activity GO:0051339 160 83 1,000 0,10806146 0,1591162 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,10863833 0,15986779 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,10863833 0,15977007 ! metencephalon development GO:0022037 30 17 0,000 0,10863833 0,15967247 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,10863833 0,15957499 ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,10863833 0,15947763 ! signal complex assembly GO:0007172 41 17 0,000 0,10863833 0,15938039 ! inositol metabolic process GO:0006020 28 17 0,000 0,10863833 0,15928326 ! gene silencing by RNA GO:0031047 36 17 0,000 0,10863833 0,15918626 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,10863833 0,15908937 ! glial cell development GO:0021782 27 17 0,000 0,10863833 0,1589926 ! limbic system development GO:0021761 36 17 0,000 0,10863833 0,15889595 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,10863833 0,15879941 ! adult walking behavior GO:0007628 33 17 0,000 0,10863833 0,15870299 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,10863833 0,15860669 ! heart looping GO:0001947 30 17 0,000 0,10863833 0,15851051 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,10863833 0,15841444 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,10863833 0,15831849 ! myoblast differentiation GO:0045445 45 17 0,000 0,10863833 0,15822266 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,10863833 0,15812694 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,10863833 0,15803134 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,10863833 0,15793585 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,10863833 0,15784048 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,10863833 0,15774522 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,10863833 0,15765008 ! membrane budding GO:0006900 37 17 0,000 0,10863833 0,15755505 ! DNA integration GO:0015074 29 17 0,000 0,10863833 0,15746014 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,10863833 0,15736534 ! regulation of protein binding GO:0043393 33 17 0,000 0,10863833 0,15727066 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,10863833 0,15717609 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,10863833 0,15708163 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,10863833 0,15698729 ! genitalia development GO:0048806 30 17 0,000 0,10863833 0,15689306 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,10863833 0,15679894 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,10863833 0,15670494 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,10863833 0,15661104 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,10863833 0,15651726 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,10863833 0,1564236 ! steroid catabolic process GO:0006706 31 17 0,000 0,10863833 0,15633004 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,10863833 0,1562366 ! gas transport GO:0015669 25 17 0,000 0,10863833 0,15614327 ! organic cation transport GO:0015695 31 17 0,000 0,10863833 0,15605005 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,10863833 0,15595694 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,10863833 0,15586394 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,10863833 0,15577106 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,10863833 0,15567828 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,10863833 0,15558561 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,1102267 0,15776648 ! nucleosome assembly GO:0006334 122 85 1,000 0,11240337 0,16078627 ! amine biosynthetic process GO:0009309 138 86 1,000 0,11459121 0,16381845 ! chromatin assembly GO:0031497 124 86 1,000 0,11459121 0,16372117 ! mitochondrion organization GO:0007005 148 86 1,000 0,11459121 0,163624 ! alcohol catabolic process GO:0046164 130 86 1,000 0,11459121 0,16352696 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,11464984 0,16351365 ! neuron maturation GO:0042551 42 18 0,000 0,11464984 0,16341678 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,11464984 0,16332003 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,11464984 0,16322339 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,11464984 0,16312686 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,11464984 0,16303045 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,11464984 0,16293415 ! memory GO:0007613 31 18 0,000 0,11464984 0,16283797 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,11464984 0,1627419 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,11464984 0,16264594 ! patterning of blood vessels GO:0001569 39 18 0,000 0,11464984 0,1625501 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,11464984 0,16245437 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,11464984 0,16235875 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,11464984 0,16226325 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,11464984 0,16216786 ! glutamine metabolic process GO:0006541 29 18 0,000 0,11464984 0,16207257 ! response to retinoic acid GO:0032526 26 18 0,000 0,11464984 0,16197741 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,11464984 0,16188235 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,11464984 0,1617874 ! response to fungus GO:0009620 21 18 0,000 0,11464984 0,16169257 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,11464984 0,16159785 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,11464984 0,16150323 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,11464984 0,16140873 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,11464984 0,16131434 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,11464984 0,16122006 ! vitamin transport GO:0051180 27 18 0,000 0,11464984 0,16112589 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,11464984 0,16103183 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,11464984 0,16093788 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,11464984 0,16084404 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,11464984 0,1607503 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,11464984 0,16065668 ! nerve development GO:0021675 28 18 0,000 0,11464984 0,16056317 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,11464984 0,16046976 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,11678997 0,16337016 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,11678997 0,16327523 ! protein secretion GO:0009306 39 19 0,000 0,12062101 0,16853318 ! positive regulation of translation GO:0045727 30 19 0,000 0,12062101 0,16843537 ! negative regulation of defense response GO:0031348 25 19 0,000 0,12062101 0,16833767 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,12062101 0,16824008 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,12062101 0,16814261 ! skin development GO:0043588 36 19 0,000 0,12062101 0,16804525 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,12062101 0,167948 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,12062101 0,16785086 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,12062101 0,16775384 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,12062101 0,16765693 ! bile acid metabolic process GO:0008206 29 19 0,000 0,12062101 0,16756013 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,12062101 0,16746344 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,12062101 0,16736687 ! cerebral cortex development GO:0021987 36 19 0,000 0,12062101 0,1672704 ! pigmentation during development GO:0048066 41 19 0,000 0,12062101 0,16717405 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,12062101 0,1670778 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,12062101 0,16698167 ! heme metabolic process GO:0042168 36 19 0,000 0,12062101 0,16688565 ! actin filament bundle formation GO:0051017 42 19 0,000 0,12062101 0,16678974 ! neuromuscular junction development GO:0007528 34 19 0,000 0,12062101 0,16669394 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,12062101 0,16659825 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,12062101 0,16650266 ! peptide cross-linking GO:0018149 37 19 0,000 0,12062101 0,16640719 ! protein export from nucleus GO:0006611 36 19 0,000 0,12062101 0,16631183 ! heart process GO:0003015 30 19 0,000 0,12062101 0,16621658 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,12062101 0,16612143 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,12062101 0,1660264 ! visual learning GO:0008542 36 19 0,000 0,12062101 0,16593147 ! cellular pigmentation GO:0033059 36 19 0,000 0,12062101 0,16583665 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,12062101 0,16574194 ! cell-cell junction organization GO:0045216 35 19 0,000 0,12062101 0,16564734 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,12062101 0,16555285 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,12062101 0,16545846 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,12062101 0,16536418 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,12062101 0,16527001 ! cilium assembly GO:0042384 37 19 0,000 0,12062101 0,16517595 ! peptide hormone secretion GO:0030072 31 19 0,000 0,12062101 0,16508199 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,12344936 0,16885683 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,12344936 0,16876089 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,1265521 0,17290423 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,1265521 0,1728061 ! positive regulation of ossification GO:0045778 47 20 0,000 0,1265521 0,17270808 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,1265521 0,17261017 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,1265521 0,17251238 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,1265521 0,17241469 ! cAMP metabolic process GO:0046058 36 20 0,000 0,1265521 0,17231712 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,1265521 0,17221965 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,1265521 0,1721223 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,1265521 0,17202505 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,1265521 0,17192792 ! response to alkaloid GO:0043279 38 20 0,000 0,1265521 0,1718309 ! retinoid metabolic process GO:0001523 32 20 0,000 0,1265521 0,17173398 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,1265521 0,17163717 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,1265521 0,17154048 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,1265521 0,17144389 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,1265521 0,17134741 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,1265521 0,17125104 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,1265521 0,17115478 ! body fluid secretion GO:0007589 31 20 0,000 0,1265521 0,17105862 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,1265521 0,17096257 ! peptide secretion GO:0002790 35 20 0,000 0,1265521 0,17086664 ! stem cell differentiation GO:0048863 53 20 0,000 0,1265521 0,17077081 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,1265521 0,17067508 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,1265521 0,17057947 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,1265521 0,17048396 ! sensory perception of pain GO:0019233 30 20 0,000 0,1265521 0,17038855 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,1265521 0,17029326 ! diencephalon development GO:0021536 34 20 0,000 0,1265521 0,17019807 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,1265521 0,17010299 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,1265521 0,17000801 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,1265521 0,16991314 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,1265521 0,16981837 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,1265521 0,16972372 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,1265521 0,16962916 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,1265521 0,16953471 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,1265521 0,16944037 ! regulation of glucose import GO:0046324 29 20 0,000 0,1265521 0,16934613 GO:0010827|regulation of glucose transport, ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,1265521 0,169252 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,1265521 0,16915797 ! negative regulation of translation GO:0017148 29 20 0,000 0,1265521 0,16906405 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,1265521 0,16897023 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,1265521 0,16887651 ! nucleosome organization GO:0034728 138 92 1,000 0,12793916 0,17063283 ! vitamin metabolic process GO:0006766 139 92 1,000 0,12793916 0,1705383 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,13019842 0,17345371 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,13019842 0,17335772 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,13244338 0,17624932 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,13244338 0,17615189 ! hormone secretion GO:0046879 38 21 0,000 0,13244338 0,17605457 ! glycerol metabolic process GO:0006071 34 21 0,000 0,13244338 0,17595736 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,13244338 0,17586025 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,13244338 0,17576325 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,13244338 0,17566636 ! axis specification GO:0009798 38 21 0,000 0,13244338 0,17556957 ! ovarian follicle development GO:0001541 35 21 0,000 0,13244338 0,17547289 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,13244338 0,17537632 ! smooth muscle contraction GO:0006939 46 21 0,000 0,13244338 0,17527985 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,13244338 0,17518349 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,13244338 0,17508724 ! cell aging GO:0007569 44 21 0,000 0,13244338 0,17499109 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,13244338 0,17489504 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,13244338 0,17479911 ! cytolysis GO:0019835 24 21 0,000 0,13244338 0,17470327 ! vasodilation GO:0042311 39 21 0,000 0,13244338 0,17460755 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,13244338 0,17451192 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,13244338 0,1744164 ! oogenesis GO:0048477 36 21 0,000 0,13244338 0,17432099 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,13244338 0,17422568 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,13244338 0,17413048 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,13244338 0,17403537 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,13244338 0,17394038 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,13244338 0,17384548 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,13244338 0,17375069 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,13244338 0,17365601 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,13244338 0,17356142 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,13244338 0,17346694 ! collagen catabolic process GO:0030574 28 21 0,000 0,13244338 0,17337256 ! sperm-egg recognition GO:0035036 21 21 0,000 0,13244338 0,17327829 ! gut development GO:0048565 39 21 0,000 0,13244338 0,17318411 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,13246695 0,17312085 ! forebrain development GO:0030900 188 95 1,000 0,13474452 0,1760018 ! positive regulation of immune response GO:0050778 156 96 1,000 0,13703091 0,17889114 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,13829512 0,18044363 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,13829512 0,18034583 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,13829512 0,18024814 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,13829512 0,18015055 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,13829512 0,18005306 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,13829512 0,17995568 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,13829512 0,17985841 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,13829512 0,17976124 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,13829512 0,17966418 ! regeneration GO:0031099 41 22 0,000 0,13829512 0,17956722 ! keratinization GO:0031424 28 22 0,000 0,13829512 0,17947037 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,13829512 0,17937362 ! sensory perception of taste GO:0050909 28 22 0,000 0,13829512 0,17927697 ! vacuolar transport GO:0007034 36 22 0,000 0,13829512 0,17918043 ! lysosome organization GO:0007040 41 22 0,000 0,13829512 0,17908399 ! central nervous system neuron development GO:0021954 46 22 0,000 0,13829512 0,17898766 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,13829512 0,17889143 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,13829512 0,1787953 ! fucose metabolic process GO:0006004 39 22 0,000 0,13829512 0,17869928 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,13829512 0,17860336 ! ureteric bud development GO:0001657 43 22 0,000 0,13829512 0,17850754 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,13829512 0,17841183 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,13829512 0,17831622 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,13829512 0,17822071 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,13829512 0,1781253 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,13829512 0,17802999 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,13829512 0,17793479 ! sarcomere organization GO:0045214 30 22 0,000 0,13829512 0,17783969 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,13829512 0,17774469 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,13829512 0,17764979 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,13829512 0,17755499 ! protein stabilization GO:0050821 39 22 0,000 0,13829512 0,1774603 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,1393259 0,17868769 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,14394079 0,18450802 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,14410758 0,18462345 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,14410758 0,1845252 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,14410758 0,18442705 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,14410758 0,184329 ! gluconeogenesis GO:0006094 33 23 0,000 0,14410758 0,18423106 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,14410758 0,18413322 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,14410758 0,18403548 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,14410758 0,18393785 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,14410758 0,18384032 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,14410758 0,1837429 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,14410758 0,18364558 ! visual behavior GO:0007632 42 23 0,000 0,14410758 0,18354836 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,14410758 0,18345124 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,14410758 0,18335423 ! peroxisome organization GO:0007031 37 23 0,000 0,14410758 0,18325732 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,14410758 0,18316051 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,14410758 0,18306381 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,14410758 0,1829672 ! sex determination GO:0007530 47 23 0,000 0,14410758 0,1828707 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,14410758 0,1827743 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,14410758 0,182678 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,14410758 0,1825818 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,14410758 0,18248571 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,14410758 0,18238971 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,14410758 0,18229382 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,14410758 0,18219803 ! platelet activation GO:0030168 37 23 0,000 0,14410758 0,18210234 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,14410758 0,18200674 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,14410758 0,18191125 ! hormone transport GO:0009914 40 23 0,000 0,14410758 0,18181586 ! cell-cell recognition GO:0009988 25 23 0,000 0,14410758 0,18172057 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,14410758 0,18162538 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,14410758 0,18153029 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,14410758 0,18143529 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,14410758 0,1813404 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,14988103 0,18850693 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,14988103 0,18840845 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,14988103 0,18831006 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,14988103 0,18821178 ! vesicle docking GO:0048278 47 24 0,000 0,14988103 0,1881136 ! spinal cord development GO:0021510 47 24 0,000 0,14988103 0,18801552 ! vacuole organization GO:0007033 43 24 0,000 0,14988103 0,18791754 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,14988103 0,18781967 ! digestive system process GO:0022600 39 24 0,000 0,14988103 0,1877219 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,14988103 0,18762423 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,14988103 0,18752666 ! regulation of behavior GO:0050795 43 24 0,000 0,14988103 0,18742919 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,14988103 0,18733183 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,14988103 0,18723456 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,14988103 0,1871374 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,14988103 0,18704033 ! membrane depolarization GO:0051899 39 24 0,000 0,14988103 0,18694337 ! pallium development GO:0021543 49 24 0,000 0,14988103 0,18684651 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,14988103 0,18674975 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,14988103 0,18665309 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,14988103 0,18655653 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,14988103 0,18646006 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,14988103 0,1863637 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,14988103 0,18626744 ! regulation of amine transport GO:0051952 40 24 0,000 0,14988103 0,18617128 ! protein tetramerization GO:0051262 52 24 0,000 0,14988103 0,18607521 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,15561573 0,19309512 ! myelination GO:0042552 45 25 0,000 0,15561573 0,19299559 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,15561573 0,19289616 ! phototransduction GO:0007602 33 25 0,000 0,15561573 0,19279683 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,15561573 0,1926976 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,15561573 0,19259848 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,15561573 0,19249945 ! sperm motility GO:0030317 31 25 0,000 0,15561573 0,19240053 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,15561573 0,19230171 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,15561573 0,192203 ! receptor metabolic process GO:0043112 46 25 0,000 0,15561573 0,19210438 ! chromosome condensation GO:0030261 45 25 0,000 0,15561573 0,19200587 ! response to starvation GO:0042594 42 25 0,000 0,15561573 0,19190745 ! osteoblast differentiation GO:0001649 60 25 0,000 0,15561573 0,19180914 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,15561573 0,19171093 ! neural crest cell development GO:0014032 54 25 0,000 0,15561573 0,19161281 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,15561573 0,1915148 ! negative regulation of cell development GO:0010721 73 25 0,000 0,15561573 0,19141689 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,15561573 0,19131908 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,15561573 0,19122137 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,15561573 0,19112376 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,15561573 0,19102624 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,15561573 0,19092883 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,15561573 0,19083152 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,15561573 0,1907343 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,15561573 0,19063719 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,15561573 0,19054017 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,15561573 0,19044325 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,15561573 0,19034644 ! telomere organization GO:0032200 43 25 0,000 0,15561573 0,19024971 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,15561573 0,19015309 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,15561573 0,19005657 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,16131193 0,19691349 ! embryonic pattern specification GO:0009880 44 26 0,000 0,16131193 0,19681364 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,16131193 0,19671388 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,16131193 0,19661423 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,16131193 0,19651468 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,16131193 0,19641523 ! molting cycle process GO:0022404 50 26 0,000 0,16131193 0,19631588 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,16131193 0,19621663 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,16131193 0,19611748 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,16131193 0,19601843 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,16131193 0,19591948 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,16131193 0,19582063 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,16131193 0,19572188 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,16131193 0,19562323 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,16131193 0,19552468 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,16131193 0,19542623 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,16131193 0,19532788 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,16131193 0,19522962 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,16131193 0,19513147 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,16131193 0,19503341 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,16131193 0,19493546 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,16131193 0,1948376 ! blastocyst development GO:0001824 49 26 0,000 0,16131193 0,19473984 ! leukocyte proliferation GO:0070661 52 26 0,000 0,16131193 0,19464217 GO:0032943|mononuclear cell proliferation, ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,16131193 0,19454461 ! neuron fate commitment GO:0048663 48 27 0,000 0,16696989 0,20126731 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,16696989 0,20116652 ! iron ion transport GO:0006826 59 27 0,000 0,16696989 0,20106584 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,16696989 0,20096525 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,16696989 0,20086477 ! superoxide metabolic process GO:0006801 38 27 0,000 0,16696989 0,20076439 ! fat cell differentiation GO:0045444 50 27 0,000 0,16696989 0,20066411 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,16696989 0,20056393 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,16696989 0,20046384 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,16696989 0,20036386 ! autophagy GO:0006914 41 27 0,000 0,16696989 0,20026398 ! male gonad development GO:0008584 44 27 0,000 0,16696989 0,2001642 ! response to toxin GO:0009636 47 27 0,000 0,16696989 0,20006451 ! primary neural tube formation GO:0014020 51 27 0,000 0,16696989 0,19996493 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,16696989 0,19986544 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,16696989 0,19976606 ! glutathione metabolic process GO:0006749 39 27 0,000 0,16696989 0,19966677 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,16696989 0,19956758 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,16696989 0,19946849 ! circadian rhythm GO:0007623 50 28 0,000 0,17258986 0,20608 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,17258986 0,20597778 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,17258986 0,20587566 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,17258986 0,20577364 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,17258986 0,20567172 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,17258986 0,20556991 ! synaptogenesis GO:0007416 42 28 0,000 0,17258986 0,20546819 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,17258986 0,20536657 ! lipid oxidation GO:0034440 43 28 0,000 0,17258986 0,20526506 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,17258986 0,20516364 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,17258986 0,20506233 ! translational initiation GO:0006413 65 29 0,000 0,17817211 0,21159037 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,17817211 0,21148599 ! regulation of pH GO:0006885 43 29 0,000 0,17817211 0,21138171 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,17817211 0,21127752 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,17817211 0,21117345 ! catechol metabolic process GO:0009712 54 29 0,000 0,17817211 0,21106947 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,17817211 0,2109656 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,17817211 0,21086183 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,17817211 0,21075816 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,17817211 0,21065459 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,17817211 0,21055113 ! cell fate determination GO:0001709 60 29 0,000 0,17817211 0,21044777 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,17817211 0,2103445 ! detection of light stimulus GO:0009583 38 29 0,000 0,17817211 0,21024134 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,17817211 0,21013828 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,17817211 0,21003532 ! tissue homeostasis GO:0001894 48 29 0,000 0,17817211 0,20993247 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,17817211 0,20982971 ! phenol metabolic process GO:0018958 55 30 0,000 0,18371688 0,21625382 ! zinc ion transport GO:0006829 45 30 0,000 0,18371688 0,21614808 ! membrane docking GO:0022406 61 30 0,000 0,18371688 0,21604243 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,18371688 0,21593689 ! cell junction assembly GO:0034329 78 30 0,000 0,18371688 0,21583145 ! regulation of innate immune response GO:0045088 51 30 0,000 0,18371688 0,21572612 ! acute-phase response GO:0006953 49 30 0,000 0,18371688 0,21562089 ! myofibril assembly GO:0030239 47 30 0,000 0,18371688 0,21551576 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,18371688 0,21541073 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,18371688 0,2153058 ! phospholipid transport GO:0015914 51 30 0,000 0,18371688 0,21520098 ! ensheathment of neurons GO:0007272 57 30 0,000 0,18371688 0,21509626 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 51 30 0,000 0,18371688 0,21499164 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,18371688 0,21488713 ! eye morphogenesis GO:0048592 60 30 0,000 0,18371688 0,21478271 ! response to heat GO:0009408 50 30 0,000 0,18371688 0,2146784 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,18922443 0,22100678 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,18922443 0,22089955 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,18922443 0,22079242 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,18922443 0,22068539 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,18922443 0,22057847 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,18922443 0,22047165 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,18922443 0,22036494 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,18922443 0,22025833 ! ovulation cycle process GO:0022602 49 31 0,000 0,18922443 0,22015182 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,18922443 0,22004542 ! peptide transport GO:0015833 55 31 0,000 0,18922443 0,21993911 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,18922443 0,21983291 ! iron ion homeostasis GO:0055072 54 31 0,000 0,18922443 0,21972682 ! mesoderm formation GO:0001707 69 31 0,000 0,18922443 0,21962082 ! natural killer cell activation GO:0030101 45 31 0,000 0,18922443 0,21951493 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,18922443 0,21940914 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,18922443 0,21930345 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,18922443 0,21919787 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,19469499 0,22542644 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,19469499 0,22531801 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,19469499 0,22520969 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,19469499 0,22510146 ! cholesterol transport GO:0030301 56 32 0,000 0,19469499 0,22499335 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,19469499 0,22488533 ! spliceosome assembly GO:0000245 67 32 0,000 0,19469499 0,22477742 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,19469499 0,22466962 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,19469499 0,22456191 ! response to ionizing radiation GO:0010212 65 32 0,000 0,19469499 0,22445431 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,19469499 0,22434681 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,19469499 0,22423942 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,19469499 0,22413213 ! muscle cell development GO:0055001 49 32 0,000 0,19469499 0,22402494 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,19469499 0,22391785 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,19469499 0,22381087 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,19469499 0,22370399 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,19469499 0,22359721 ! ovulation cycle GO:0042698 51 32 0,000 0,19469499 0,22349053 ! peripheral nervous system development GO:0007422 64 32 0,000 0,19469499 0,22338395 ! BMP signaling pathway GO:0030509 64 32 0,000 0,19469499 0,22327748 ! hindbrain development GO:0030902 61 32 0,000 0,19469499 0,2231711 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,19469499 0,22306483 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,19469499 0,22295866 ! gene silencing GO:0016458 65 32 0,000 0,19469499 0,22285259 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,20012883 0,22896336 ! post-embryonic development GO:0009791 69 33 0,000 0,20012883 0,22885454 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,20012883 0,22874582 ! protein targeting to membrane GO:0006612 68 33 0,000 0,20012883 0,22863721 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,20012883 0,22852869 ! ceramide metabolic process GO:0006672 64 33 0,000 0,20012883 0,22842028 ! formation of primary germ layer GO:0001704 72 33 0,000 0,20012883 0,22831197 ! cell fate specification GO:0001708 52 33 0,000 0,20012883 0,22820377 ! sterol transport GO:0015918 57 33 0,000 0,20012883 0,22809567 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,20012883 0,22798767 GO:0060326|cell chemotaxis, ! negative regulation of protein transport GO:0051224 69 33 0,000 0,20012883 0,22787977 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,20012883 0,22777197 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,20552617 0,23380424 ! glial cell differentiation GO:0010001 63 34 0,000 0,20552617 0,23369375 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,20552617 0,23358336 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,20552617 0,23347308 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,20552617 0,2333629 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,20552617 0,23325282 ! mismatch repair GO:0006298 46 34 0,000 0,20552617 0,23314285 ! spermatid development GO:0007286 63 34 0,000 0,20552617 0,23303298 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,20552617 0,23292321 ! placenta development GO:0001890 53 34 0,000 0,20552617 0,23281355 ! regulation of muscle development GO:0048634 70 35 0,000 0,21088728 0,23877402 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,21088728 0,23866171 ! negative regulation of secretion GO:0051048 63 35 0,000 0,21088728 0,23854951 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,21088728 0,23843741 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,21088728 0,23832541 ! odontogenesis GO:0042476 66 35 0,000 0,21088728 0,23821352 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,21088728 0,23810174 ! female gonad development GO:0008585 58 35 0,000 0,21088728 0,23799006 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,21088728 0,23787848 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,21088728 0,23776701 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,21088728 0,23765564 ! cytokine production GO:0001816 59 35 0,000 0,21088728 0,23754438 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,21088728 0,23743322 ! neural tube formation GO:0001841 67 35 0,000 0,21088728 0,23732217 ! vesicle localization GO:0051648 64 35 0,000 0,21088728 0,23721122 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,21621239 0,24308739 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,21621239 0,24297385 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,21621239 0,24286041 ! cell junction organization GO:0034330 86 36 0,000 0,21621239 0,24274709 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,21621239 0,24263387 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,21621239 0,24252075 ! positive regulation of cell development GO:0010720 80 36 0,000 0,21621239 0,24240774 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,21621239 0,24229483 ! regulation of proteolysis GO:0030162 72 36 0,000 0,21621239 0,24218203 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,21621239 0,24206934 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,21621239 0,24195675 ! aerobic respiration GO:0009060 55 36 0,000 0,21621239 0,24184426 ! embryonic organ development GO:0048568 57 36 0,000 0,21621239 0,24173188 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,21621239 0,2416196 ! RNA export from nucleus GO:0006405 56 37 0,000 0,22150174 0,24741559 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,22150174 0,24730078 ! actomyosin structure organization GO:0031032 62 37 0,000 0,22150174 0,24718608 ! organic anion transport GO:0015711 68 37 0,000 0,22150174 0,24707148 ! tissue remodeling GO:0048771 76 37 0,000 0,22150174 0,24695699 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,22150174 0,2468426 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,22150174 0,24672832 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,22150174 0,24661415 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,22150174 0,24650008 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,22150174 0,24638612 ! pigment metabolic process GO:0042440 80 37 0,000 0,22150174 0,24627226 ! spermatid differentiation GO:0048515 66 37 0,000 0,22150174 0,24615851 ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,22675557 0,25188084 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,22675557 0,2517646 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,22675557 0,25164847 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,22675557 0,25153245 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,22675557 0,25141654 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,22675557 0,25130073 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,22675557 0,25118503 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,22675557 0,25106944 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,22675557 0,25095395 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,22675557 0,25083857 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,22675557 0,2507233 ! glucan metabolic process GO:0044042 62 38 0,000 0,22675557 0,25060813 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,23197411 0,2562579 ! learning GO:0007612 77 39 0,000 0,23197411 0,2561403 ! ear morphogenesis GO:0042471 60 39 0,000 0,23197411 0,2560228 ! organic ether metabolic process GO:0018904 55 39 0,000 0,23197411 0,25590542 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,23197411 0,25578813 ! ion transmembrane transport GO:0034220 66 39 0,000 0,23197411 0,25567096 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,23197411 0,2555539 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,23197411 0,25543694 ! RNA modification GO:0009451 57 39 0,000 0,23197411 0,25532009 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,23715761 0,2609059 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,23715761 0,26078666 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,23715761 0,26066752 ! feeding behavior GO:0007631 59 40 0,000 0,23715761 0,2605485 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,23715761 0,26042958 ! maintenance of protein location GO:0045185 91 40 0,000 0,23715761 0,26031077 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,24230629 0,26584083 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,24230629 0,26571966 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,24230629 0,26559861 ! gliogenesis GO:0042063 88 41 0,000 0,24230629 0,26547766 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,24230629 0,26535682 ! female gamete generation GO:0007292 61 41 0,000 0,24230629 0,2652361 ! polyol metabolic process GO:0019751 66 41 0,000 0,24230629 0,26511548 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,24230629 0,26499497 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,2474204 0,27046501 ! regulation of tube size GO:0035150 71 42 0,000 0,2474204 0,27034218 GO:0050880|regulation of blood vessel size, ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,2474204 0,27021946 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,2474204 0,27009686 ! regulation of protein secretion GO:0050708 71 42 0,000 0,2474204 0,26997437 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,25250015 0,27539228 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,25250015 0,2752675 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,25250015 0,27514283 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,25250015 0,27501828 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,25250015 0,27489383 ! glucose transport GO:0015758 65 43 0,000 0,25250015 0,2747695 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,25250015 0,27464529 ! neural tube development GO:0021915 77 43 0,000 0,25250015 0,27452118 ! striated muscle contraction GO:0006941 77 43 0,000 0,25250015 0,27439719 ! phagocytosis GO:0006909 90 43 0,000 0,25250015 0,27427331 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,25250015 0,27414954 ! hexose transport GO:0008645 67 44 0,000 0,25754579 0,27950166 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,25754579 0,27937564 ! male sex differentiation GO:0046661 76 44 0,000 0,25754579 0,27924974 ! biopolymer methylation GO:0043414 84 44 0,000 0,25754579 0,27912395 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,25754579 0,27899828 ! developmental growth GO:0048589 82 44 0,000 0,25754579 0,27887272 ! maintenance of location in cell GO:0051651 97 44 0,000 0,25754579 0,27874727 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,26255754 0,28404381 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,26255754 0,28391615 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,26255754 0,2837886 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,26255754 0,28366117 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,26255754 0,28353386 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,26255754 0,28340665 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,26255754 0,28327957 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,26753562 0,28852115 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,26753562 0,28839189 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,26753562 0,28826274 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,26753562 0,2881337 ! positive regulation of defense response GO:0031349 76 47 0,000 0,27248026 0,29332774 ! response to calcium ion GO:0051592 81 47 0,000 0,27248026 0,29319655 ! endosome transport GO:0016197 108 47 0,000 0,27248026 0,29306549 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,27248026 0,29293454 ! JNK cascade GO:0007254 91 47 0,000 0,27248026 0,29280371 ! methylation GO:0032259 90 47 0,000 0,27248026 0,29267299 ! protein homooligomerization GO:0051260 76 47 0,000 0,27248026 0,29254239 ! mitochondrial transport GO:0006839 82 48 0,000 0,27739168 0,2976826 ! Notch signaling pathway GO:0007219 96 48 0,000 0,27739168 0,29754988 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,27739168 0,29741728 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,27739168 0,2972848 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,27739168 0,29715244 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,28227011 0,30224383 ! regulation of action potential GO:0001508 95 49 0,000 0,28227011 0,30210938 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,28227011 0,30197505 ! regulation of ion transport GO:0043269 77 49 0,000 0,28227011 0,30184084 ! peptide metabolic process GO:0006518 76 49 0,000 0,28227011 0,30170674 ! response to temperature stimulus GO:0009266 76 49 0,000 0,28227011 0,30157277 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,28227011 0,30143892 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,28227011 0,30130518 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,28227011 0,30117157 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,28227011 0,30103807 ! neuromuscular process GO:0050905 99 50 0,000 0,28711576 0,30607024 ! regulation of ossification GO:0030278 117 50 0,000 0,28711576 0,30593469 ! inner ear development GO:0048839 79 50 0,000 0,28711576 0,30579926 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,28711576 0,30566395 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,28711576 0,30552876 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,29192887 0,3105132 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,29192887 0,31037598 ! excretion GO:0007588 83 51 0,000 0,29192887 0,31023889 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,29192887 0,31010192 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,29192887 0,30996507 ! vesicle organization GO:0016050 107 51 0,000 0,29192887 0,30982834 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,29192887 0,30969173 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,29670963 0,31462467 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,29670963 0,31448606 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,29670963 0,31434759 ! amino acid activation GO:0043038 92 52 0,000 0,29670963 0,31420923 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,29670963 0,31407099 ! synapse organization GO:0050808 85 52 0,000 0,29670963 0,31393288 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,30145827 0,31881697 ! RNA catabolic process GO:0006401 93 53 0,000 0,30145827 0,31867689 ! regulation of translational initiation GO:0006446 82 53 0,000 0,30145827 0,31853694 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,30145827 0,3183971 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,30145827 0,31825739 ! cell maturation GO:0048469 100 53 0,000 0,30145827 0,31811781 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,30145827 0,31797834 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,30617501 0,32281204 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,30617501 0,32267064 ! cell recognition GO:0008037 85 54 0,000 0,30617501 0,32252937 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,30617501 0,32238821 ! chloride transport GO:0006821 90 55 0,000 0,31086005 0,32717817 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,31086005 0,32703511 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,31086005 0,32689217 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,31086005 0,32674936 ! gastrulation GO:0007369 112 55 0,000 0,31086005 0,32660667 ! heart morphogenesis GO:0003007 97 55 0,000 0,31086005 0,32646411 ! RNA elongation GO:0006354 79 55 0,000 0,31086005 0,32632168 ! nuclear export GO:0051168 97 55 0,000 0,31086005 0,32617937 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,31086005 0,32603718 ! sensory perception of smell GO:0007608 80 56 0,000 0,31551362 0,33077375 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,31551362 0,33062969 ! regulation of DNA replication GO:0006275 101 56 0,000 0,31551362 0,33048575 ! proton transport GO:0015992 94 56 0,000 0,31551362 0,33034193 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,32013591 0,33503567 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,32013591 0,33489 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,32013591 0,33474446 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,32013591 0,33459904 ! maintenance of location GO:0051235 118 57 0,000 0,32013591 0,33445375 ! hydrogen transport GO:0006818 97 58 0,000 0,32472714 0,33910308 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,32472714 0,33895596 ! regulation of endocytosis GO:0030100 91 58 0,000 0,32472714 0,33880897 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,32472714 0,33866211 ! positive regulation of secretion GO:0051047 95 59 0,000 0,32928752 0,3432694 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,32928752 0,34312073 GO:0032313|regulation of Rab GTPase activity, ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,33381725 0,34769017 ! camera-type eye development GO:0043010 116 60 0,000 0,33381725 0,34753972 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,33831653 0,35207162 ! mesoderm development GO:0007498 119 61 0,000 0,33831653 0,3519194 ! tRNA processing GO:0008033 89 61 0,000 0,33831653 0,35176732 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,33831653 0,35161537 ! ear development GO:0043583 103 62 0,000 0,34278558 0,35610627 ! gonad development GO:0008406 98 62 0,000 0,34278558 0,35595257 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,34278558 0,35579901 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,3472246 0,36025113 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,35163377 0,36466847 ! single fertilization GO:0007338 75 64 0,000 0,35163377 0,36451136 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,35163377 0,36435438 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,35601331 0,36873355 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,35601331 0,36857489 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,35601331 0,36841636 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,35601331 0,36825797 ! actin filament organization GO:0007015 148 66 0,000 0,36036342 0,3725975 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,36036342 0,37243745 ! extracellular matrix organization GO:0030198 133 66 0,000 0,36036342 0,37227754 ! developmental maturation GO:0021700 116 66 0,000 0,36036342 0,37211776 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,36468428 0,37641801 ! activation of MAPK activity GO:0000187 115 67 0,000 0,36468428 0,37625659 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,36468428 0,37609532 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,36468428 0,37593418 ! amino acid transport GO:0006865 125 68 0,000 0,3689761 0,3801955 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,3689761 0,38003274 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,3689761 0,37987013 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,37323906 0,3840946 ! appendage morphogenesis GO:0035107 135 70 0,000 0,37747337 0,38828599 GO:0035108|limb morphogenesis, ! reproductive structure development GO:0048608 113 71 0,000 0,38167921 0,39244452 ! appendage development GO:0048736 136 71 0,000 0,38167921 0,39227688 GO:0060173|limb development, ! carbohydrate transport GO:0008643 110 72 0,000 0,38585678 0,39640111 ! learning or memory GO:0007611 147 73 0,000 0,39000625 0,40049298 ! regulation of blood pressure GO:0008217 125 73 0,000 0,39000625 0,40032212 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,39000625 0,40015141 ! axon guidance GO:0007411 139 73 0,000 0,39000625 0,39998084 ! fertilization GO:0009566 90 73 0,000 0,39000625 0,39981042 ! transition metal ion transport GO:0000041 126 74 0,000 0,39412783 0,40386353 ! neurotransmitter transport GO:0006836 123 74 0,000 0,39412783 0,4036916 ! exocytosis GO:0006887 133 74 0,000 0,39412783 0,40351982 ! eye development GO:0001654 143 74 0,000 0,39412783 0,40334818 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,3982217 0,40736455 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,3982217 0,40719142 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,3982217 0,40701844 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,3982217 0,40684561 ! rhythmic process GO:0048511 128 75 0,000 0,3982217 0,40667292 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,40228804 0,41065126 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,40228804 0,41047711 ! defense response to bacterium GO:0042742 89 76 0,000 0,40228804 0,41030311 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,40632704 0,41424697 ! blood coagulation GO:0007596 146 78 0,000 0,41033888 0,41815982 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,41033888 0,41798278 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,41033888 0,4178059 ! protein oligomerization GO:0051259 139 78 0,000 0,41033888 0,41762916 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,41432374 0,42150652 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,41432374 0,42132836 ! response to metal ion GO:0010038 140 80 0,000 0,4182818 0,42517364 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,4182818 0,42499409 ! inorganic anion transport GO:0015698 138 80 0,000 0,4182818 0,42481469 ! digestion GO:0007586 112 81 0,000 0,42221324 0,42862661 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,42221324 0,42844583 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,42221324 0,4282652 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,42611825 0,43204404 ! response to drug GO:0042493 143 82 0,000 0,42611825 0,43186205 ! hemostasis GO:0007599 158 84 0,000 0,43384964 0,43951252 ! negative regulation of transport GO:0051051 153 84 0,000 0,43384964 0,43932754 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,43384964 0,43914272 ! response to unfolded protein GO:0006986 131 85 0,000 0,43767638 0,44282985 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,43767638 0,44264371 ! response to inorganic substance GO:0010035 153 86 0,000 0,44147739 0,44630025 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,44147739 0,44611281 ! tube morphogenesis GO:0035239 176 86 0,000 0,44147739 0,44592552 ! amine transport GO:0015837 155 86 0,000 0,44147739 0,44573839 ! regulation of protein transport GO:0051223 154 87 0,000 0,44525282 0,4493617 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,44900286 0,45295634 ! regulation of neurological system process GO:0031644 148 88 0,000 0,44900286 0,45276651 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,44900286 0,45257683 ! cellular defense response GO:0006968 114 89 0,000 0,45272767 0,45614019 ! ossification GO:0001503 188 90 0,000 0,45642743 0,45967534 ! sex differentiation GO:0007548 145 90 0,000 0,45642743 0,45948301 ! bone development GO:0060348 189 91 0,000 0,4601023 0,46298876 ! sterol metabolic process GO:0016125 152 91 0,000 0,4601023 0,4627952 ! response to protein stimulus GO:0051789 149 91 0,000 0,4601023 0,46260181 ! regulation of defense response GO:0031347 149 92 0,000 0,46375244 0,46607702 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,46375244 0,46588241 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,46737803 0,46932869 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,46737803 0,46913289 ! regulation of membrane potential GO:0042391 164 93 0,000 0,46737803 0,46893725 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,46737803 0,46874178 ! female pregnancy GO:0007565 164 94 0,000 0,47097922 0,47215667 ! transcription initiation GO:0006352 153 94 0,000 0,47097922 0,47196002 ! mRNA transport GO:0051028 169 96 0,000 0,47810909 0,47890527 ! hormone metabolic process GO:0042445 157 97 0,000 0,48163808 0,48223937 ! regulation of protein localization GO:0032880 176 97 0,000 0,48163808 0,48203877 ! response to virus GO:0009615 160 98 0,000 0,48514332 0,48534505 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,48862498 0,48862498