pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/941-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of lipid kinase activity GO:0043550 17 8 3,000 9,984E-08 2,439E-04 ! actin filament-based movement GO:0030048 47 21 4,000 1,666E-07 2,035E-04 ! establishment or maintenance of cell polarity GO:0007163 96 41 5,000 2,024E-07 1,648E-04 ! myeloid cell differentiation GO:0030099 126 67 6,000 2,07E-07 1,264E-04 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 3,000 2,966E-07 1,449E-04 GO:0007520|myoblast fusion, ! syncytium formation GO:0006949 20 11 3,000 4,638E-07 1,889E-04 ! ribosomal large subunit biogenesis GO:0042273 13 13 3,000 9,952E-07 3,473E-04 ! myotube differentiation GO:0014902 26 14 3,000 1,386E-06 4,234E-04 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 2,000 2,35E-06 6,378E-04 ! regulation of keratinocyte differentiation GO:0045616 6 5 2,000 2,35E-06 5,74E-04 ! leukocyte differentiation GO:0002521 232 98 6,000 2,797E-06 6,212E-04 ! filopodium assembly GO:0046847 42 17 3,000 3,249E-06 6,613E-04 ! endothelial cell migration GO:0043542 31 17 3,000 3,249E-06 6,105E-04 ! microspike assembly GO:0030035 46 18 3,000 4,156E-06 7,253E-04 ! nuclear migration GO:0007097 13 6 2,000 4,678E-06 7,618E-04 ! establishment of spindle localization GO:0051293 16 6 2,000 4,678E-06 7,142E-04 GO:0051653|spindle localization, ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 4,678E-06 6,722E-04 GO:0031272|regulation of pseudopodium assembly, ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 4,000 7,052E-06 9,571E-04 ! plasma membrane fusion GO:0045026 33 21 3,000 8,011E-06 1,03E-03 ! regulation of epidermal cell differentiation GO:0045604 8 7 2,000 8,148E-06 9,953E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 4,000 9,891E-06 1,151E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 1,298E-05 1,441E-03 ! establishment of nucleus localization GO:0040023 18 8 2,000 1,298E-05 1,378E-03 ! positive regulation of epidermis development GO:0045684 13 8 2,000 1,298E-05 1,321E-03 ! myeloid leukocyte differentiation GO:0002573 46 25 3,000 1,66E-05 1,623E-03 ! UTP metabolic process GO:0046051 10 9 2,000 1,938E-05 1,821E-03 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! macrophage differentiation GO:0030225 15 9 2,000 1,938E-05 1,753E-03 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 3,000 1,953E-05 1,704E-03 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 2,000 2,755E-05 2,321E-03 ! CTP metabolic process GO:0046036 11 10 2,000 2,755E-05 2,244E-03 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 10 2,000 2,755E-05 2,171E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 4,000 2,858E-05 2,182E-03 ! establishment of organelle localization GO:0051656 122 59 4,000 3,383E-05 2,504E-03 ! negative regulation of protein complex assembly GO:0031333 68 30 3,000 3,511E-05 2,523E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 5,000 3,528E-05 2,463E-03 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 2,000 3,771E-05 2,559E-03 ! nucleus localization GO:0051647 22 11 2,000 3,771E-05 2,49E-03 ! regulation of B cell proliferation GO:0030888 22 12 2,000 5,005E-05 3,218E-03 ! regulation of cell projection assembly GO:0060491 33 12 2,000 5,005E-05 3,135E-03 ! establishment of cell polarity GO:0030010 21 12 2,000 5,005E-05 3,057E-03 ! steroid hormone receptor signaling pathway GO:0030518 146 66 4,000 5,83E-05 3,474E-03 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 2,000 6,477E-05 3,767E-03 ! regulation of epidermis development GO:0045682 19 13 2,000 6,477E-05 3,68E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 4,000 7,221E-05 4,009E-03 ! negative regulation of kinase activity GO:0033673 145 70 4,000 7,737E-05 4,201E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 4,000 8,282E-05 4,398E-03 ! negative regulation of transferase activity GO:0051348 155 74 4,000 1,009E-04 5,246E-03 ! organelle localization GO:0051640 155 74 4,000 1,009E-04 5,137E-03 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 2,000 1,021E-04 5,09E-03 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 2,000 1,251E-04 6,112E-03 ! cytokinesis GO:0000910 84 42 3,000 1,352E-04 6,479E-03 ! negative regulation of cell cycle process GO:0010948 35 17 2,000 1,512E-04 7,103E-03 ! meiosis GO:0007126 143 81 4,000 1,55E-04 7,144E-03 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 4,000 1,55E-04 7,011E-03 ! meiotic cell cycle GO:0051321 144 82 4,000 1,642E-04 7,294E-03 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 2,000 1,806E-04 7,879E-03 ! detection of bacterium GO:0016045 22 18 2,000 1,806E-04 7,74E-03 ! positive regulation of DNA binding GO:0043388 83 48 3,000 2,284E-04 9,619E-03 ! regulation of DNA binding GO:0051101 167 89 4,000 2,412E-04 9,986E-03 ! estrogen receptor signaling pathway GO:0030520 45 20 2,000 2,5E-04 0,01017911 ! regulation of cell cycle process GO:0010564 161 90 4,000 2,541E-04 0,01017563 ! induction of apoptosis by extracellular signals GO:0008624 99 50 3,000 2,677E-04 0,01054714 ! negative regulation of immune system process GO:0002683 101 51 3,000 2,89E-04 0,01120856 ! positive regulation of binding GO:0051099 88 52 3,000 3,116E-04 0,011895 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 2,000 3,346E-04 0,01257705 ! G1 phase GO:0051318 44 22 2,000 3,346E-04 0,01238649 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 2,000 3,346E-04 0,01220162 ! membrane fusion GO:0006944 122 54 3,000 3,605E-04 0,01295164 ! regulation of cell shape GO:0008360 142 54 3,000 3,605E-04 0,01276393 ! benzene and derivative metabolic process GO:0042537 12 5 1,000 3,801E-04 0,0132666 ! selenocysteine incorporation GO:0001514 12 5 1,000 3,801E-04 0,01307975 GO:0006451|translational readthrough, ! 2-oxoglutarate metabolic process GO:0006103 10 5 1,000 3,801E-04 0,01289808 ! depurination GO:0045007 5 5 1,000 3,801E-04 0,0127214 ! meiotic chromosome segregation GO:0045132 10 5 1,000 3,801E-04 0,01254949 ! negative regulation of T cell mediated immunity GO:0002710 15 5 1,000 3,801E-04 0,01238216 GO:0002707|negative regulation of lymphocyte mediated immunity, ! indolalkylamine catabolic process GO:0046218 8 5 1,000 3,801E-04 0,01221924 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! metaphase GO:0051323 11 5 1,000 3,801E-04 0,01206055 ! stem cell division GO:0017145 11 5 1,000 3,801E-04 0,01190592 GO:0048103|somatic stem cell division, ! regulation of Rho GTPase activity GO:0032319 56 23 2,000 3,831E-04 0,01184599 ! skeletal muscle tissue development GO:0007519 223 100 4,000 4,139E-04 0,01264082 GO:0060538|skeletal muscle organ development, ! skeletal muscle fiber development GO:0048741 130 56 3,000 4,146E-04 0,01250584 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 4,358E-04 0,01298332 ! negative regulation of phosphorylation GO:0042326 52 24 2,000 4,358E-04 0,01282689 ! detection of biotic stimulus GO:0009595 34 24 2,000 4,358E-04 0,01267419 ! pyrimidine nucleoside metabolic process GO:0006213 34 24 2,000 4,358E-04 0,01252508 ! muscle fiber development GO:0048747 131 57 3,000 4,438E-04 0,01260645 ! dicarboxylic acid metabolic process GO:0043648 48 25 2,000 4,93E-04 0,01384227 ! DNA catabolic process GO:0006308 94 60 3,000 5,399E-04 0,01498926 ! response to interferon-gamma GO:0034341 16 6 1,000 5,679E-04 0,01558741 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 5,679E-04 0,01541421 ! glutamate catabolic process GO:0006538 12 6 1,000 5,679E-04 0,01524483 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 1,000 5,679E-04 0,01507912 GO:0033135|regulation of peptidyl-serine phosphorylation, ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 5,679E-04 0,01491698 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 1,000 5,679E-04 0,01475829 ! activation of Ras GTPase activity GO:0032856 13 6 1,000 5,679E-04 0,01460294 GO:0032862|activation of Rho GTPase activity, ! regulation of T cell receptor signaling pathway GO:0050856 11 6 1,000 5,679E-04 0,01445083 ! negative regulation of B cell activation GO:0050869 14 6 1,000 5,679E-04 0,01430185 ! metallo-sulfur cluster assembly GO:0031163 6 6 1,000 5,679E-04 0,01415591 GO:0016226|iron-sulfur cluster assembly, ! positive regulation of cell projection organization GO:0031346 66 27 2,000 6,212E-04 0,01532888 ! regulation of chromosome organization GO:0033044 49 27 2,000 6,212E-04 0,01517559 ! regulation of protein complex assembly GO:0043254 132 63 3,000 6,5E-04 0,01572308 ! regulation of lipid metabolic process GO:0019216 132 66 3,000 7,752E-04 0,01856589 ! cytokinesis during cell cycle GO:0033205 14 7 1,000 7,917E-04 0,01877892 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 7,917E-04 0,01859835 ! tryptophan metabolic process GO:0006568 11 7 1,000 7,917E-04 0,01842123 ! monocyte differentiation GO:0030224 16 7 1,000 7,917E-04 0,01824744 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 1,000 7,917E-04 0,0180769 ! oxaloacetate metabolic process GO:0006107 13 7 1,000 7,917E-04 0,01790952 ! aspartate family amino acid catabolic process GO:0009068 10 7 1,000 7,917E-04 0,01774522 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 1,000 7,917E-04 0,0175839 ! negative regulation of cell growth GO:0030308 142 67 3,000 8,204E-04 0,01805617 ! regulation of B cell activation GO:0050864 55 30 2,000 8,505E-04 0,01855086 ! cell projection assembly GO:0030031 138 68 3,000 8,675E-04 0,01875417 ! negative regulation of cell size GO:0045792 144 69 3,000 9,164E-04 0,01963841 ! homeostasis of number of cells GO:0048872 131 69 3,000 9,164E-04 0,01946764 ! cellular amino acid catabolic process GO:0009063 120 69 3,000 9,164E-04 0,01929982 ! erythrocyte differentiation GO:0030218 62 31 2,000 9,373E-04 0,019571 ! spindle organization GO:0007051 50 32 2,000 1,03E-03 0,02131487 ! male meiosis GO:0007140 9 8 1,000 1,051E-03 0,02158323 ! carbohydrate phosphorylation GO:0046835 11 8 1,000 1,051E-03 0,02140337 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,051E-03 0,02122648 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 1,051E-03 0,02105249 ! lymph node development GO:0048535 11 8 1,000 1,051E-03 0,02088133 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 1,000 1,051E-03 0,02071293 ! NAD biosynthetic process GO:0009435 17 8 1,000 1,051E-03 0,02054723 ! lymphocyte differentiation GO:0030098 193 76 3,000 1,315E-03 0,02549173 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,346E-03 0,02589535 ! glycine catabolic process GO:0006546 15 9 1,000 1,346E-03 0,02569304 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 1,346E-03 0,02549387 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 1,346E-03 0,02529776 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 1,000 1,346E-03 0,02510465 GO:0002820|negative regulation of adaptive immune response, ! regulation of macrophage differentiation GO:0045649 16 9 1,000 1,346E-03 0,02491446 ! amine catabolic process GO:0009310 136 77 3,000 1,38E-03 0,02535062 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 2,000 1,455E-03 0,02653002 ! steroid biosynthetic process GO:0006694 146 79 3,000 1,518E-03 0,0274626 ! xenobiotic metabolic process GO:0006805 55 37 2,000 1,576E-03 0,02831673 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 1,576E-03 0,02811004 ! negative regulation of organelle organization GO:0010639 181 80 3,000 1,59E-03 0,0281434 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,676E-03 0,02945366 ! regulation of phosphatase activity GO:0010921 28 10 1,000 1,676E-03 0,02924327 ! SMAD protein nuclear translocation GO:0007184 21 10 1,000 1,676E-03 0,02903587 ! base-excision repair, AP site formation GO:0006285 15 10 1,000 1,676E-03 0,02883139 ! serine family amino acid catabolic process GO:0009071 18 10 1,000 1,676E-03 0,02862978 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 1,000 1,676E-03 0,02843096 ! negative regulation of immune effector process GO:0002698 23 10 1,000 1,676E-03 0,02823488 ! meiosis I GO:0007127 74 38 2,000 1,704E-03 0,02850769 ! erythrocyte homeostasis GO:0034101 75 39 2,000 1,837E-03 0,03053358 ! negative regulation of growth GO:0045926 168 85 3,000 1,987E-03 0,03279496 ! cortical actin cytoskeleton organization GO:0030866 29 11 1,000 2,04E-03 0,03344547 ! thyroid gland development GO:0030878 26 11 1,000 2,04E-03 0,0332225 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 2,04E-03 0,03300249 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 2,04E-03 0,03278536 ! regulation of lipoprotein lipase activity GO:0051004 23 11 1,000 2,04E-03 0,03257108 ! positive regulation of Rho GTPase activity GO:0032321 31 11 1,000 2,04E-03 0,03235958 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 1,000 2,04E-03 0,03215081 ! regulation of embryonic development GO:0045995 35 11 1,000 2,04E-03 0,03194471 ! ribonucleoside metabolic process GO:0009119 64 42 2,000 2,277E-03 0,03542388 ! regulation of T cell differentiation GO:0045580 78 42 2,000 2,277E-03 0,03519968 ! response to xenobiotic stimulus GO:0009410 63 42 2,000 2,277E-03 0,0349783 ! cortical cytoskeleton organization GO:0030865 30 12 1,000 2,438E-03 0,03722247 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 1,000 2,438E-03 0,03699128 GO:0043088|regulation of Cdc42 GTPase activity, ! entry into host cell GO:0030260 34 12 1,000 2,438E-03 0,03676293 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 27 12 1,000 2,438E-03 0,03653739 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,438E-03 0,03631461 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 2,438E-03 0,03609452 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 15 12 1,000 2,438E-03 0,03587708 ! regulation of cell morphogenesis GO:0022604 243 93 3,000 2,757E-03 0,04032552 ! B cell differentiation GO:0030183 124 45 2,000 2,776E-03 0,0403636 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 2,776E-03 0,04012476 ! nitrogen compound catabolic process GO:0044270 167 94 3,000 2,865E-03 0,04117586 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 2,869E-03 0,04099217 GO:0000725|recombinational repair, ! endocrine pancreas development GO:0031018 25 13 1,000 2,869E-03 0,04075385 ! indolalkylamine metabolic process GO:0006586 19 13 1,000 2,869E-03 0,04051828 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 2,869E-03 0,04028541 ! membrane protein proteolysis GO:0033619 33 13 1,000 2,869E-03 0,04005521 GO:0006509|membrane protein ectodomain proteolysis, ! aromatic amino acid family catabolic process GO:0009074 20 13 1,000 2,869E-03 0,03982762 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 1,000 2,869E-03 0,03960261 ! biogenic amine catabolic process GO:0042402 24 13 1,000 2,869E-03 0,03938012 ! cell growth GO:0016049 90 46 2,000 2,956E-03 0,04034203 ! deoxyribonucleotide catabolic process GO:0009264 21 14 1,000 3,334E-03 0,04524738 ! positive regulation of Ras GTPase activity GO:0032320 42 14 1,000 3,334E-03 0,0449974 ! response to calcium ion GO:0051592 94 49 2,000 3,539E-03 0,04750307 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 3,539E-03 0,04724349 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 3,539E-03 0,04698673 ! endocrine system development GO:0035270 109 50 2,000 3,748E-03 0,04949007 ! activation of caspase activity GO:0006919 95 50 2,000 3,748E-03 0,049224 ! lactation GO:0007595 30 15 1,000 3,831E-03 0,05004899 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 3,831E-03 0,04978277 ! positive regulation of GTPase activity GO:0043547 43 15 1,000 3,831E-03 0,04951937 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 3,831E-03 0,04925874 ! regulation of T cell mediated immunity GO:0002709 36 15 1,000 3,831E-03 0,04900084 ! epithelial to mesenchymal transition GO:0001837 30 15 1,000 3,831E-03 0,04874563 ! regulation of cell projection organization GO:0031344 135 51 2,000 3,964E-03 0,05017491 ! viral infectious cycle GO:0019058 104 51 2,000 3,964E-03 0,04991628 ! glutamate metabolic process GO:0006536 25 16 1,000 4,36E-03 0,05462836 ! regulation of dephosphorylation GO:0035303 43 16 1,000 4,36E-03 0,05434964 ! negative regulation of immune response GO:0050777 38 16 1,000 4,36E-03 0,05407375 ! regulation of ATPase activity GO:0043462 26 16 1,000 4,36E-03 0,05380065 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 1,000 4,36E-03 0,0535303 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 4,36E-03 0,05326265 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 4,419E-03 0,05370482 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! induction of apoptosis via death domain receptors GO:0008625 23 17 1,000 4,922E-03 0,05952287 ! NAD metabolic process GO:0019674 33 17 1,000 4,922E-03 0,05922965 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 4,922E-03 0,05893931 ! cellular amino acid derivative catabolic process GO:0042219 30 17 1,000 4,922E-03 0,0586518 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 1,000 4,922E-03 0,05836708 ! positive regulation of caspase activity GO:0043280 108 57 2,000 5,42E-03 0,06396271 GO:0010952|positive regulation of peptidase activity, ! glycine metabolic process GO:0006544 30 18 1,000 5,514E-03 0,06476645 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 6,138E-03 0,07174612 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 1,000 6,138E-03 0,07140447 GO:0019692|deoxyribose phosphate metabolic process, ! response to fungus GO:0009620 26 19 1,000 6,138E-03 0,07106606 ! heterocycle catabolic process GO:0046700 100 60 2,000 6,253E-03 0,07205386 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 6,792E-03 0,07790227 ! protein amino acid acetylation GO:0006473 41 20 1,000 6,792E-03 0,07753824 ! response to vitamin GO:0033273 36 20 1,000 6,792E-03 0,07717759 ! pancreas development GO:0031016 40 20 1,000 6,792E-03 0,07682029 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 6,792E-03 0,07646628 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 6,792E-03 0,07611552 ! purine nucleotide catabolic process GO:0006195 32 20 1,000 6,792E-03 0,07576796 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 1,000 6,792E-03 0,07542356 ! aromatic compound catabolic process GO:0019439 31 20 1,000 6,792E-03 0,07508228 ! negative regulation of T cell activation GO:0050868 41 20 1,000 6,792E-03 0,07474407 ! viral reproductive process GO:0022415 132 62 2,000 6,848E-03 0,07502275 ! DNA damage response, signal transduction GO:0042770 136 62 2,000 6,848E-03 0,07468783 ! nucleoside metabolic process GO:0009116 91 62 2,000 6,848E-03 0,07435588 ! regulation of mitosis GO:0007088 112 63 2,000 7,158E-03 0,07737688 GO:0051783|regulation of nuclear division, ! regulation of cell killing GO:0031341 46 21 1,000 7,477E-03 0,08046332 ! lipid phosphorylation GO:0046834 43 21 1,000 7,477E-03 0,08011041 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 7,477E-03 0,07976058 ! D-ribose metabolic process GO:0006014 36 22 1,000 8,191E-03 0,08699974 ! apoptotic nuclear changes GO:0030262 34 22 1,000 8,191E-03 0,08662312 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 8,191E-03 0,08624974 ! positive regulation of B cell activation GO:0050871 42 22 1,000 8,191E-03 0,08587957 ! response to cytokine stimulus GO:0034097 69 22 1,000 8,191E-03 0,08551256 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 8,191E-03 0,08514868 ! detection of external stimulus GO:0009581 102 68 2,000 8,831E-03 0,09142082 ! viral reproduction GO:0016032 142 68 2,000 8,831E-03 0,09103508 ! viral genome replication GO:0019079 44 23 1,000 8,934E-03 0,09170807 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 8,934E-03 0,09132436 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 1,000 8,934E-03 0,09094384 ! response to ethanol GO:0045471 47 23 1,000 8,934E-03 0,09056648 ! deoxyribonucleotide metabolic process GO:0009262 37 23 1,000 8,934E-03 0,09019224 ! DNA modification GO:0006304 36 23 1,000 8,934E-03 0,08982107 ! fatty acid transport GO:0015908 47 23 1,000 8,934E-03 0,08945296 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 9,707E-03 0,0967917 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 9,707E-03 0,09639823 ! barbed-end actin filament capping GO:0051016 58 24 1,000 9,707E-03 0,09600796 GO:0051693|actin filament capping, ! aromatic amino acid family metabolic process GO:0009072 37 24 1,000 9,707E-03 0,09562083 ! glutamine family amino acid catabolic process GO:0009065 45 24 1,000 9,707E-03 0,09523681 ! aspartate family amino acid metabolic process GO:0009066 47 24 1,000 9,707E-03 0,09485586 ! cell cycle checkpoint GO:0000075 145 71 2,000 9,936E-03 0,09671008 ! B cell activation GO:0042113 179 72 2,000 0,01032152 0,10006136 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 0,01050812 0,10146771 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 0,01050812 0,10106823 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 0,01050812 0,10067188 ! interaction with host GO:0051701 66 25 1,000 0,01050812 0,10027863 ! regulation of caspase activity GO:0043281 136 74 2,000 0,01111782 0,1056842 ! initiation of viral infection GO:0019059 60 26 1,000 0,01133757 0,10735535 ! pentose metabolic process GO:0019321 43 26 1,000 0,01133757 0,10694085 ! positive regulation of nuclear division GO:0051785 41 26 1,000 0,01133757 0,10652954 GO:0045840|positive regulation of mitosis, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 1,000 0,01133757 0,10612138 ! regulation of transcription factor activity GO:0051090 137 75 2,000 0,01152891 0,10750053 GO:0090046|regulation of transcription regulator activity, ! negative regulation of actin filament depolymerization GO:0030835 63 27 1,000 0,01219488 0,11327791 ! negative regulation of actin filament polymerization GO:0030837 61 27 1,000 0,01219488 0,11284882 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 0,01219488 0,11242298 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 0,01219488 0,11200033 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 0,01237713 0,11324842 ! positive regulation of lymphocyte activation GO:0051251 142 78 2,000 0,01281431 0,11681101 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 0,01307967 0,11878677 ! protein amino acid acylation GO:0043543 59 28 1,000 0,01307967 0,11834682 ! negative regulation of protein modification process GO:0031400 66 28 1,000 0,01307967 0,11791012 ! vitamin biosynthetic process GO:0009110 48 28 1,000 0,01307967 0,11747662 ! base-excision repair GO:0006284 41 28 1,000 0,01307967 0,11704631 ! positive regulation of T cell differentiation GO:0045582 48 28 1,000 0,01307967 0,11661913 ! negative regulation of protein polymerization GO:0032272 63 28 1,000 0,01307967 0,11619506 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 0,01326023 0,11737225 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 1,000 0,01399158 0,12339866 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! somitogenesis GO:0001756 52 29 1,000 0,01399158 0,12295478 ! regulation of peptidase activity GO:0052547 150 82 2,000 0,01465071 0,12828558 ! regulation of actin filament depolymerization GO:0030834 67 30 1,000 0,01493023 0,13026626 ! complement activation, classical pathway GO:0006958 51 30 1,000 0,01493023 0,12980268 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 1,000 0,01493023 0,12934239 ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 0,01493023 0,12888535 ! nicotinamide metabolic process GO:0006769 56 30 1,000 0,01493023 0,12843153 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 0,01493023 0,12798089 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of phosphorus metabolic process GO:0010562 156 83 2,000 0,01513184 0,12925551 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 2,000 0,01513184 0,12880514 ! response to metal ion GO:0010038 158 84 2,000 0,01562181 0,13251421 ! T cell activation GO:0042110 189 84 2,000 0,01562181 0,13205569 ! regulation of ligase activity GO:0051340 147 84 2,000 0,01562181 0,13160032 ! alkaloid metabolic process GO:0009820 57 31 1,000 0,01589526 0,13344372 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 0,01589526 0,13298672 ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 0,01589526 0,13253284 ! positive regulation of cell activation GO:0050867 161 86 2,000 0,01662838 0,13817393 GO:0002696|positive regulation of leukocyte activation, ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 1,000 0,01688631 0,13984154 ! metanephros development GO:0001656 81 32 1,000 0,01688631 0,1393691 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 1,000 0,01688631 0,13889984 ! pyridine nucleotide metabolic process GO:0019362 60 33 1,000 0,01790302 0,1467687 ! response to inorganic substance GO:0010035 173 90 2,000 0,01874831 0,15318438 ! positive regulation of protein modification process GO:0031401 156 90 2,000 0,01874831 0,15267376 ! serine family amino acid metabolic process GO:0009069 56 34 1,000 0,01894503 0,15376318 ! adult locomotory behavior GO:0008344 62 34 1,000 0,01894503 0,15325403 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,01894503 0,15274824 ! gland development GO:0048732 220 91 2,000 0,01930061 0,15510322 ! regulation of cell adhesion GO:0030155 241 92 2,000 0,01986184 0,15909005 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,02110358 0,16848381 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 1,000 0,02110358 0,16793501 ! negative regulation of DNA binding GO:0043392 67 36 1,000 0,02110358 0,16738976 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,02110358 0,16684805 ! cofactor biosynthetic process GO:0051188 161 95 2,000 0,02159921 0,17021569 ! regulation of T cell activation GO:0050863 175 96 2,000 0,02219623 0,17435819 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,02221942 0,17398091 ! sister chromatid segregation GO:0000819 65 37 1,000 0,02221942 0,17342506 ! negative regulation of cell activation GO:0050866 69 37 1,000 0,02221942 0,17287276 ! regulation of protein stability GO:0031647 77 38 1,000 0,02335918 0,18116345 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 0,02335918 0,18059014 ! negative regulation of binding GO:0051100 71 39 1,000 0,02452253 0,18898594 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 1,000 0,02452253 0,18839164 ! nucleotide catabolic process GO:0009166 70 39 1,000 0,02452253 0,18780107 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,02452253 0,18721419 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 1,000 0,02570913 0,19566168 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 1,000 0,02570913 0,19505403 ! nucleus organization GO:0006997 73 40 1,000 0,02570913 0,19445015 ! cellular amide metabolic process GO:0043603 73 41 1,000 0,02691864 0,20296989 ! mesenchymal cell development GO:0014031 94 41 1,000 0,02691864 0,20234537 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! T cell differentiation GO:0030217 93 42 1,000 0,02815075 0,21095791 ! regulation of leukocyte mediated immunity GO:0002703 84 42 1,000 0,02815075 0,21031278 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,02940512 0,21901436 GO:0090047|positive regulation of transcription regulator activity, ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,02940512 0,21834866 ! monocarboxylic acid transport GO:0015718 93 43 1,000 0,02940512 0,217687 ! regulation of T cell proliferation GO:0042129 80 43 1,000 0,02940512 0,21702933 ! segmentation GO:0035282 78 43 1,000 0,02940512 0,21637563 ! neuron migration GO:0001764 85 43 1,000 0,02940512 0,21572585 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 0,02940512 0,21507997 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,03068144 0,22374551 ! double-strand break repair GO:0006302 85 44 1,000 0,03068144 0,2230796 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,03070574 0,22259384 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,03070574 0,22193527 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,03070574 0,2212806 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03070574 0,22062977 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,03070574 0,21998277 ! neuron fate determination GO:0048664 7 5 0,000 0,03070574 0,21933954 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03070574 0,21870007 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,03070574 0,21806431 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,03070574 0,21743224 ! polyol transport GO:0015791 12 5 0,000 0,03070574 0,21680382 ! response to superoxide GO:0000303 10 5 0,000 0,03070574 0,21617903 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03070574 0,21555782 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,03070574 0,21494018 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,03070574 0,21432607 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03070574 0,21371545 ! female meiosis GO:0007143 10 5 0,000 0,03070574 0,2131083 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,03070574 0,2125046 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03070574 0,2119043 ! hypothalamus development GO:0021854 9 5 0,000 0,03070574 0,21130739 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,03070574 0,21071383 ! cobalt ion transport GO:0006824 11 5 0,000 0,03070574 0,21012359 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,03070574 0,20953666 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,03070574 0,20895299 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03070574 0,20837256 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03070574 0,20779535 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,03070574 0,20722133 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,03070574 0,20665048 GO:0048596|embryonic camera-type eye morphogenesis, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03070574 0,20608276 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,03070574 0,20551814 ! transposition GO:0032196 9 5 0,000 0,03070574 0,20495662 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,03070574 0,20439816 ! negative chemotaxis GO:0050919 16 5 0,000 0,03070574 0,20384273 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,03070574 0,20329031 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03070574 0,20274087 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,03070574 0,2021944 ! behavioral response to pain GO:0048266 10 5 0,000 0,03070574 0,20165087 ! clathrin coat assembly GO:0048268 15 5 0,000 0,03070574 0,20111025 ! Notch receptor processing GO:0007220 11 5 0,000 0,03070574 0,20057252 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03070574 0,20003766 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,03070574 0,19950565 ! micturition GO:0060073 9 5 0,000 0,03070574 0,19897645 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03070574 0,19845006 ! copulation GO:0007620 9 5 0,000 0,03070574 0,19792645 ! glial cell fate commitment GO:0021781 14 5 0,000 0,03070574 0,19740559 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,03070574 0,19688746 ! bioluminescence GO:0008218 9 5 0,000 0,03070574 0,19637205 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03070574 0,19585933 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03070574 0,19534928 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03070574 0,19484188 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,03070574 0,19433711 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03070574 0,19383494 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,03070574 0,19333537 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03070574 0,19283836 ! grooming behavior GO:0007625 6 5 0,000 0,03070574 0,1923439 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,03070574 0,19185198 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03070574 0,19136256 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,03070574 0,19087563 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03070574 0,19039117 ! response to protozoan GO:0001562 13 5 0,000 0,03070574 0,18990917 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,03070574 0,1894296 ! lymph vessel development GO:0001945 10 5 0,000 0,03070574 0,18895245 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,03070574 0,1884777 ! endochondral ossification GO:0001958 17 5 0,000 0,03070574 0,18800532 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03070574 0,18753531 ! single strand break repair GO:0000012 8 5 0,000 0,03070574 0,18706764 ! parathyroid gland development GO:0060017 14 5 0,000 0,03070574 0,1866023 ! anagen GO:0042640 7 5 0,000 0,03070574 0,18613926 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03070574 0,18567852 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,03070574 0,18522006 ! cytokine secretion GO:0050663 15 5 0,000 0,03070574 0,18476385 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,03070574 0,18430988 ! ceramide catabolic process GO:0046514 7 5 0,000 0,03070574 0,18385814 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,03070574 0,18340861 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,03070574 0,18296128 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03070574 0,18251611 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03070574 0,18207311 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,03070574 0,18163226 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,03070574 0,18119353 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03070574 0,18075692 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,03070574 0,18032241 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03070574 0,17988998 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,03070574 0,17945962 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03070574 0,17903132 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,03070574 0,17860505 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03070574 0,17818081 ! microvillus organization GO:0032528 8 5 0,000 0,03070574 0,17775859 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,03070574 0,17733835 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,03070574 0,1769201 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,03070574 0,17650382 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,03070574 0,17608949 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,03070574 0,1756771 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,03070574 0,17526664 ! polyol catabolic process GO:0046174 9 5 0,000 0,03070574 0,1748581 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,03070574 0,17445145 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,03070574 0,17404669 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,03070574 0,1736438 ! muscle cell migration GO:0014812 8 5 0,000 0,03070574 0,17324278 ! mitochondrial fission GO:0000266 8 5 0,000 0,03070574 0,1728436 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,03070574 0,17244626 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,03070574 0,17205074 ! mRNA transcription GO:0009299 10 5 0,000 0,03070574 0,17165703 ! nerve growth factor processing GO:0032455 9 5 0,000 0,03070574 0,17126512 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,03070574 0,170875 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,03070574 0,17048664 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,03070574 0,17010005 ! monocyte activation GO:0042117 10 5 0,000 0,03070574 0,16971521 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03070574 0,16933211 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03070574 0,16895073 ! response to food GO:0032094 6 5 0,000 0,03070574 0,16857106 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,03070574 0,1681931 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03070574 0,16781683 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,03070574 0,16744224 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03070574 0,16706932 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,03070574 0,16669805 ! forebrain neuron development GO:0021884 13 5 0,000 0,03070574 0,16632843 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03070574 0,16596045 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,03070574 0,16559409 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,03070574 0,16522935 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03070574 0,1648662 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03070574 0,16450466 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,03070574 0,16414469 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,03070574 0,16378629 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,03070574 0,16342946 ! lipid glycosylation GO:0030259 7 5 0,000 0,03070574 0,16307418 ! nucleobase transport GO:0015851 6 5 0,000 0,03070574 0,16272044 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03070574 0,16236823 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,03070574 0,16201754 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,03070574 0,16166837 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,03070574 0,16132069 ! basic amino acid transport GO:0015802 12 5 0,000 0,03070574 0,16097451 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,03070574 0,16062981 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,03070574 0,16028659 ! actin nucleation GO:0045010 11 5 0,000 0,03070574 0,15994482 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03070574 0,15960452 ! depyrimidination GO:0045008 10 5 0,000 0,03070574 0,15926565 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03070574 0,15892823 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03070574 0,15859223 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,03070574 0,15825764 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,03070574 0,15792447 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,03070574 0,1575927 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,03070574 0,15726231 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03070574 0,15693331 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03070574 0,15660568 ! activated T cell proliferation GO:0050798 16 5 0,000 0,03070574 0,15627942 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03070574 0,15595452 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,03070574 0,15563096 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03070574 0,15530874 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03070574 0,15498786 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,03070574 0,15466829 ! response to arsenic GO:0046685 11 5 0,000 0,03070574 0,15435005 ! mast cell degranulation GO:0043303 7 5 0,000 0,03070574 0,15403311 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,03070574 0,15371746 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,03070574 0,15340311 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,03070574 0,15309005 ! response to mercury ion GO:0046689 8 5 0,000 0,03070574 0,15277825 ! response to cadmium ion GO:0046686 7 5 0,000 0,03070574 0,15246773 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,03070574 0,15215846 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,03070574 0,15185045 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,03070574 0,15154368 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,03070574 0,15123815 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,03070574 0,15093385 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,03070574 0,15063077 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03070574 0,1503289 ! decidualization GO:0046697 11 5 0,000 0,03070574 0,15002825 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,03070574 0,14972879 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,03070574 0,14943052 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,03070574 0,14913345 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,03070574 0,14883755 ! embryonic cleavage GO:0040016 6 5 0,000 0,03070574 0,14854282 ! peroxisome fission GO:0016559 5 5 0,000 0,03070574 0,14824925 ! histone demethylation GO:0016577 13 5 0,000 0,03070574 0,14795685 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,03070574 0,1476656 ! mitotic recombination GO:0006312 9 5 0,000 0,03070574 0,14737549 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,03070574 0,14708652 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03070574 0,14679867 ! metaphase plate congression GO:0051310 7 5 0,000 0,03070574 0,14651196 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03070574 0,14622636 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,03070574 0,14594187 ! enteric nervous system development GO:0048484 8 5 0,000 0,03070574 0,14565849 ! lymphocyte costimulation GO:0031294 8 5 0,000 0,03070574 0,14537621 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,03070574 0,14509502 ! muscle cell proliferation GO:0033002 12 5 0,000 0,03070574 0,14481491 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03070574 0,14453588 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,03070574 0,14425793 ! B cell homeostasis GO:0001782 13 5 0,000 0,03070574 0,14398104 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,03070574 0,14370522 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03070574 0,14343045 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,03070574 0,14315672 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,03070574 0,14288404 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03070574 0,1426124 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03070574 0,14234179 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,03070574 0,1420722 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,03070574 0,14180363 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03070574 0,14153608 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,03070574 0,14126953 ! response to redox state GO:0051775 6 5 0,000 0,03070574 0,14100399 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,03070574 0,14073944 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,03070574 0,14047589 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,03070574 0,14021331 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,03070574 0,13995172 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03070574 0,1396911 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,03070574 0,13943146 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03070574 0,13917277 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,03070574 0,13891504 ! striatum development GO:0021756 14 5 0,000 0,03070574 0,13865827 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,03070574 0,13840244 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03070574 0,13814756 ! glial cell migration GO:0008347 10 5 0,000 0,03070574 0,13789361 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,03070574 0,13764059 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,03070574 0,1373885 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,03070574 0,13713734 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03070574 0,13688709 ! T cell activation during immune response GO:0002286 9 5 0,000 0,03070574 0,13663775 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03070574 0,13638931 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03070574 0,13614178 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,03070574 0,13589515 ! neuroprotection GO:0043526 8 5 0,000 0,03070574 0,13564941 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,03070574 0,13540455 ! regulation of sensory perception GO:0051931 8 5 0,000 0,03070574 0,13516058 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03070574 0,13491749 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,03070574 0,13467527 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,03070574 0,13443391 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,03070574 0,13419342 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03070574 0,13395379 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,03070574 0,13371501 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03070574 0,13347709 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,03070574 0,13324001 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,03070574 0,13300376 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,03070574 0,13276836 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03070574 0,13253379 ! spindle assembly GO:0051225 6 5 0,000 0,03070574 0,13230004 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,03070574 0,13206712 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03070574 0,13183501 ! protein palmitoylation GO:0018345 12 5 0,000 0,03070574 0,13160372 ! drug metabolic process GO:0017144 7 5 0,000 0,03070574 0,13137325 ! phospholipid scrambling GO:0017121 8 5 0,000 0,03070574 0,13114357 ! organ regeneration GO:0031100 7 5 0,000 0,03070574 0,1309147 ! carnitine metabolic process GO:0009437 8 5 0,000 0,03070574 0,13068663 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03070574 0,13045934 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 0,03197938 0,13563475 ! keratinocyte differentiation GO:0030216 81 45 1,000 0,03197938 0,13539968 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 1,000 0,03197938 0,13516542 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 1,000 0,03197938 0,13493198 ! activation of adenylate cyclase activity GO:0007190 94 46 1,000 0,03329863 0,14025611 ! regulation of actin filament polymerization GO:0030833 99 46 1,000 0,03329863 0,1400147 ! glycolysis GO:0006096 71 46 1,000 0,03329863 0,13977413 ! leukocyte migration GO:0050900 75 46 1,000 0,03329863 0,13953438 ! pigmentation GO:0043473 103 46 1,000 0,03329863 0,13929545 ! regulation of JNK cascade GO:0046328 104 47 1,000 0,03463887 0,1446543 ! response to insulin stimulus GO:0032868 98 47 1,000 0,03463887 0,14440745 ! positive regulation of cell cycle GO:0045787 96 48 1,000 0,03599981 0,14982543 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 1,000 0,03599981 0,14957062 ! cellular component disassembly GO:0022411 89 48 1,000 0,03599981 0,14931668 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 0,03599981 0,1490636 ! regulation of adaptive immune response GO:0002819 92 48 1,000 0,03599981 0,14881138 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03673332 0,15158698 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03673332 0,15133135 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03673332 0,15107659 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03673332 0,15082267 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03673332 0,15056962 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03673332 0,15031741 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03673332 0,15006604 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03673332 0,14981551 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03673332 0,14956582 ! response to oxygen radical GO:0000305 11 6 0,000 0,03673332 0,14931696 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03673332 0,14906892 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03673332 0,14882171 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03673332 0,14857532 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03673332 0,14832974 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03673332 0,14808497 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03673332 0,14784101 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03673332 0,14759785 ! forebrain regionalization GO:0021871 9 6 0,000 0,03673332 0,14735549 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03673332 0,14711392 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03673332 0,14687315 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03673332 0,14663316 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03673332 0,14639395 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,03673332 0,14615552 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03673332 0,14591787 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03673332 0,14568099 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03673332 0,14544488 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03673332 0,14520953 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03673332 0,14497495 ! malate metabolic process GO:0006108 13 6 0,000 0,03673332 0,14474112 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03673332 0,14450804 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03673332 0,14427571 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03673332 0,14404413 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03673332 0,14381329 ! protein refolding GO:0042026 15 6 0,000 0,03673332 0,14358319 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03673332 0,14335382 ! opsonization GO:0008228 8 6 0,000 0,03673332 0,14312519 ! mating behavior GO:0007617 7 6 0,000 0,03673332 0,14289728 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03673332 0,1426701 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03673332 0,14244364 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03673332 0,14221789 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03673332 0,14199287 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03673332 0,14176855 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03673332 0,14154494 ! toxin metabolic process GO:0009404 11 6 0,000 0,03673332 0,14132203 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03673332 0,14109983 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03673332 0,14087832 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03673332 0,14065751 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03673332 0,14043739 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03673332 0,14021796 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03673332 0,13999921 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03673332 0,13978114 ! thymic T cell selection GO:0045061 16 6 0,000 0,03673332 0,13956375 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03673332 0,13934704 ! protein lipoylation GO:0009249 10 6 0,000 0,03673332 0,13913099 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03673332 0,13891562 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03673332 0,13870091 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03673332 0,13848687 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03673332 0,13827348 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03673332 0,13806076 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03673332 0,13784868 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! response to pH GO:0009268 10 6 0,000 0,03673332 0,13763726 ! hyperosmotic response GO:0006972 10 6 0,000 0,03673332 0,13742648 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03673332 0,13721635 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03673332 0,13700686 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03673332 0,13679801 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03673332 0,13658979 ! urea metabolic process GO:0019627 7 6 0,000 0,03673332 0,13638221 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03673332 0,13617525 ! neutrophil activation GO:0042119 7 6 0,000 0,03673332 0,13596893 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03673332 0,13576322 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03673332 0,13555814 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03673332 0,13535368 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03673332 0,13514984 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03673332 0,1349466 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03673332 0,13474398 ! neuron apoptosis GO:0051402 15 6 0,000 0,03673332 0,13454197 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03673332 0,13434056 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03673332 0,13413975 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03673332 0,13393954 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03673332 0,13373993 ! carnitine transport GO:0015879 10 6 0,000 0,03673332 0,13354091 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03673332 0,13334248 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03673332 0,13314465 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03673332 0,13294739 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,03673332 0,13275073 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03673332 0,13255464 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03673332 0,13235913 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03673332 0,1321642 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03673332 0,13196984 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03673332 0,13177605 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03673332 0,13158283 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03673332 0,13139018 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,03673332 0,13119809 ! response to UV-C GO:0010225 14 6 0,000 0,03673332 0,13100656 ! astrocyte development GO:0014002 16 6 0,000 0,03673332 0,13081559 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03673332 0,13062517 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03673332 0,13043531 ! interaction with symbiont GO:0051702 14 6 0,000 0,03673332 0,130246 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03673332 0,13005723 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03673332 0,12986902 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03673332 0,12968135 ! response to copper ion GO:0046688 10 6 0,000 0,03673332 0,12949422 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03673332 0,12930762 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03673332 0,12912157 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03673332 0,12893605 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03673332 0,12875106 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03673332 0,12856661 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03673332 0,12838268 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03673332 0,12819927 ! hair follicle maturation GO:0048820 8 6 0,000 0,03673332 0,12801639 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03673332 0,12783403 ! Schwann cell development GO:0014044 15 6 0,000 0,03673332 0,12765219 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03673332 0,12747087 ! response to pheromone GO:0019236 6 6 0,000 0,03673332 0,12729006 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03673332 0,12710976 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03673332 0,12692997 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03673332 0,12675069 ! subpallium development GO:0021544 15 6 0,000 0,03673332 0,12657192 ! neural tube patterning GO:0021532 8 6 0,000 0,03673332 0,12639365 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03673332 0,12621588 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03673332 0,12603861 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03673332 0,12586184 ! G2 phase GO:0051319 16 6 0,000 0,03673332 0,12568556 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03673332 0,12550978 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03673332 0,12533449 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03673332 0,12515968 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03673332 0,12498536 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03673332 0,12481153 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03673332 0,12463818 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03673332 0,12446531 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03673332 0,12429292 ! receptor internalization GO:0031623 11 6 0,000 0,03673332 0,12412101 ! plasminogen activation GO:0031639 9 6 0,000 0,03673332 0,12394957 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03673332 0,12377861 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03673332 0,12360812 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03673332 0,12343809 ! protein deubiquitination GO:0016579 16 6 0,000 0,03673332 0,12326853 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,03673332 0,12309944 ! protein destabilization GO:0031648 9 6 0,000 0,03673332 0,12293081 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03673332 0,12276264 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03673332 0,12259493 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03673332 0,12242768 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03673332 0,12226089 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03673332 0,12209455 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03673332 0,12192866 ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03673332 0,12176322 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03673332 0,12159823 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03673332 0,12143368 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03673332 0,12126958 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03673332 0,12110593 ! neural plate development GO:0001840 9 6 0,000 0,03673332 0,12094271 ! catecholamine transport GO:0051937 9 6 0,000 0,03673332 0,12077993 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03673332 0,1206176 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03673332 0,12045569 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03673332 0,12029422 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,03673332 0,12013319 ! maternal placenta development GO:0001893 12 6 0,000 0,03673332 0,11997258 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03673332 0,11981241 ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03673332 0,11965266 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03673332 0,11949333 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03673332 0,11933443 GO:0055081|anion homeostasis, ! positive regulation of cyclase activity GO:0031281 106 49 1,000 0,03738112 0,12127766 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 0,03878251 0,1256574 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 1,000 0,03878251 0,12549096 ! epidermal cell differentiation GO:0009913 87 50 1,000 0,03878251 0,12532497 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,04164433 0,13439511 ! cellular amino acid biosynthetic process GO:0008652 80 52 1,000 0,04164433 0,1342178 ! histone modification GO:0016570 104 52 1,000 0,04164433 0,13404097 ! tRNA transcription GO:0009304 17 7 0,000 0,04272358 0,13733382 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,04272358 0,13715335 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,04272358 0,13697336 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04272358 0,13679384 ! regulation of helicase activity GO:0051095 16 7 0,000 0,04272358 0,13661479 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,04272358 0,13643621 ! sleep GO:0030431 16 7 0,000 0,04272358 0,1362581 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04272358 0,13608045 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,04272358 0,13590326 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04272358 0,13572653 ! prostate gland development GO:0030850 14 7 0,000 0,04272358 0,13555026 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,04272358 0,13537445 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04272358 0,1351991 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04272358 0,13502419 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,04272358 0,13484974 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04272358 0,13467574 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,04272358 0,13450219 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,04272358 0,13432909 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04272358 0,13415643 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,04272358 0,13398421 ! glycolipid transport GO:0046836 11 7 0,000 0,04272358 0,13381244 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04272358 0,1336411 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,04272358 0,13347021 ! neuron adhesion GO:0007158 14 7 0,000 0,04272358 0,13329975 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04272358 0,13312972 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04272358 0,13296013 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,04272358 0,13279097 ! mRNA stabilization GO:0048255 18 7 0,000 0,04272358 0,13262224 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,04272358 0,13245394 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,04272358 0,13228606 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,04272358 0,13211861 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,04272358 0,13195158 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,04272358 0,13178498 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04272358 0,13161879 ! lipoprotein transport GO:0042953 14 7 0,000 0,04272358 0,13145303 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,04272358 0,13128768 ! rhythmic behavior GO:0007622 17 7 0,000 0,04272358 0,13112274 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,04272358 0,13095822 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,04272358 0,13079411 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,04272358 0,13063042 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,04272358 0,13046713 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04272358 0,13030425 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,04272358 0,13014177 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04272358 0,1299797 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,04272358 0,12981804 ! mechanosensory behavior GO:0007638 16 7 0,000 0,04272358 0,12965677 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,04272358 0,12949591 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,04272358 0,12933544 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,04272358 0,12917537 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,04272358 0,1290157 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04272358 0,12885642 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04272358 0,12869754 ! spinal cord patterning GO:0021511 14 7 0,000 0,04272358 0,12853904 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,04272358 0,12838094 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,04272358 0,12822322 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04272358 0,12806589 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,04272358 0,12790895 ! adrenal gland development GO:0030325 17 7 0,000 0,04272358 0,12775239 ! cysteine metabolic process GO:0006534 13 7 0,000 0,04272358 0,12759621 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,04272358 0,12744042 ! ovulation GO:0030728 10 7 0,000 0,04272358 0,127285 ! adenohypophysis development GO:0021984 11 7 0,000 0,04272358 0,12712997 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,04272358 0,12697531 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,04272358 0,12682102 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,04272358 0,12666711 ! microtubule nucleation GO:0007020 21 7 0,000 0,04272358 0,12651358 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04272358 0,12636041 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04272358 0,12620762 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,04272358 0,1260552 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,04272358 0,12590314 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04272358 0,12575145 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,04272358 0,12560012 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,04272358 0,12544916 ! galactose metabolic process GO:0006012 13 7 0,000 0,04272358 0,12529856 ! vesicle fusion GO:0006906 20 7 0,000 0,04272358 0,12514832 ! response to dietary excess GO:0002021 8 7 0,000 0,04272358 0,12499845 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04272358 0,12484893 ! intracellular pH reduction GO:0051452 13 7 0,000 0,04272358 0,12469976 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04272358 0,12455096 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,04272358 0,12440251 ! organ growth GO:0035265 15 7 0,000 0,04272358 0,12425441 ! nucleoside transport GO:0015858 11 7 0,000 0,04272358 0,12410666 ! nucleoside salvage GO:0043174 11 7 0,000 0,04272358 0,12395927 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,04272358 0,12381222 ! male sex determination GO:0030238 15 7 0,000 0,04272358 0,12366552 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,04272358 0,12351917 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,04272358 0,12337317 ! parturition GO:0007567 16 7 0,000 0,04272358 0,12322751 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,04272358 0,1230822 ! rRNA modification GO:0000154 14 7 0,000 0,04272358 0,12293722 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,04272358 0,12279259 ! spindle checkpoint GO:0031577 16 7 0,000 0,04272358 0,1226483 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,04272358 0,12250435 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,04272358 0,12236073 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,04272358 0,12221745 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04272358 0,12207451 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,04272358 0,12193189 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,04272358 0,12178962 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,04272358 0,12164767 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04272358 0,12150606 ! fibrinolysis GO:0042730 11 7 0,000 0,04272358 0,12136477 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,04272358 0,12122381 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,04272358 0,12108318 ! eating behavior GO:0042755 8 7 0,000 0,04272358 0,12094288 ! B cell lineage commitment GO:0002326 21 7 0,000 0,04272358 0,1208029 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04272358 0,12066324 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,04272358 0,12052391 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,04272358 0,12038489 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04272358 0,1202462 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,04272358 0,12010783 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04272358 0,11996977 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,04272358 0,11983203 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,04272358 0,11969461 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,04272358 0,11955751 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04272358 0,11942071 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,04272358 0,11928423 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04272358 0,11914806 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04272358 0,1190122 ! histone ubiquitination GO:0016574 9 7 0,000 0,04272358 0,11887665 ! regulation of meiosis GO:0040020 12 7 0,000 0,04272358 0,11874141 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,04272358 0,11860648 ! T cell lineage commitment GO:0002360 16 7 0,000 0,04272358 0,11847185 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,04272358 0,11833753 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04272358 0,11820351 ! membrane to membrane docking GO:0022614 14 7 0,000 0,04272358 0,1180698 ! transcription termination GO:0006353 14 7 0,000 0,04272358 0,11793639 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04272358 0,11780328 ! anaphase GO:0051322 18 7 0,000 0,04272358 0,11767046 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,04272358 0,11753795 ! axonal fasciculation GO:0007413 19 7 0,000 0,04272358 0,11740574 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,04272358 0,11727382 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,04272358 0,1171422 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,04272358 0,11701088 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,04272358 0,11687985 ! diuresis GO:0030146 12 7 0,000 0,04272358 0,11674911 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04272358 0,11661866 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04272358 0,11648851 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04272358 0,11635864 ! antibiotic transport GO:0042891 9 7 0,000 0,04272358 0,11622907 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,04272358 0,11609978 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,04272358 0,11597078 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,04272358 0,11584207 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,04272358 0,11571364 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,04272358 0,1155855 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04272358 0,11545764 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04272358 0,11533006 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,04272358 0,11520276 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,04272358 0,11507575 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,04272358 0,11494901 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,04272358 0,11482255 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,04272358 0,11469638 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,04272358 0,11457047 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,04272358 0,11444485 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,04272358 0,1143195 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04272358 0,11419442 ! muscle adaptation GO:0043500 13 7 0,000 0,04272358 0,11406962 ! embryonic heart tube development GO:0035050 14 7 0,000 0,04272358 0,11394509 ! retina homeostasis GO:0001895 12 7 0,000 0,04272358 0,11382083 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,04272358 0,11369684 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,04272358 0,11357313 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,04272358 0,11344968 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,04272358 0,1133265 ! positive regulation of growth GO:0045927 96 53 1,000 0,04310416 0,114212 ! chromatin remodeling GO:0006338 122 53 1,000 0,04310416 0,11408826 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 1,000 0,04310416 0,11396479 ! covalent chromatin modification GO:0016569 115 54 1,000 0,04458289 0,11774701 ! glutamine family amino acid metabolic process GO:0009064 85 54 1,000 0,04458289 0,11761986 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 1,000 0,04608021 0,12143901 ! regulation of multicellular organism growth GO:0040014 90 55 1,000 0,04608021 0,12130815 ! regulation of protein polymerization GO:0032271 117 55 1,000 0,04608021 0,12117757 ! response to UV GO:0009411 120 55 1,000 0,04608021 0,12104727 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,04759586 0,1248944 ! glucose catabolic process GO:0006007 88 56 1,000 0,04759586 0,12476039 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,04759586 0,12462667 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04867676 0,12732047 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04867676 0,1271843 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,04867676 0,12704841 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,04867676 0,12691282 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04867676 0,12677752 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04867676 0,12664251 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04867676 0,12650778 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04867676 0,12637334 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04867676 0,12623919 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04867676 0,12610532 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04867676 0,12597173 ! meiotic prophase I GO:0007128 14 8 0,000 0,04867676 0,12583843 ! response to zinc ion GO:0010043 12 8 0,000 0,04867676 0,12570541 ! oligopeptide transport GO:0006857 16 8 0,000 0,04867676 0,12557267 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04867676 0,12544021 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04867676 0,12530803 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04867676 0,12517612 ! signal peptide processing GO:0006465 12 8 0,000 0,04867676 0,1250445 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04867676 0,12491315 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04867676 0,12478207 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04867676 0,12465127 ! succinate metabolic process GO:0006105 17 8 0,000 0,04867676 0,12452075 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04867676 0,1243905 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04867676 0,12426052 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04867676 0,12413081 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04867676 0,12400137 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04867676 0,1238722 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04867676 0,12374331 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04867676 0,12361467 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04867676 0,12348631 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04867676 0,12335821 ! reflex GO:0060004 17 8 0,000 0,04867676 0,12323038 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04867676 0,12310281 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04867676 0,12297551 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,04867676 0,12284847 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04867676 0,12272169 ! pigment granule organization GO:0048753 17 8 0,000 0,04867676 0,12259517 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04867676 0,12246891 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04867676 0,12234292 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04867676 0,12221718 ! astrocyte differentiation GO:0048708 19 8 0,000 0,04867676 0,1220917 ! histidine catabolic process GO:0006548 10 8 0,000 0,04867676 0,12196648 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04867676 0,12184151 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04867676 0,1217168 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04867676 0,12159235 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,04867676 0,12146815 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04867676 0,1213442 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,04867676 0,12122051 ! melanin metabolic process GO:0006582 17 8 0,000 0,04867676 0,12109706 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04867676 0,12097387 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04867676 0,12085093 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04867676 0,12072824 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04867676 0,1206058 ! macrophage activation GO:0042116 13 8 0,000 0,04867676 0,1204836 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04867676 0,12036166 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,04867676 0,12023996 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04867676 0,1201185 ! purine salvage GO:0043101 12 8 0,000 0,04867676 0,11999729 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04867676 0,11987633 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04867676 0,11975561 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04867676 0,11963513 ! osteoblast development GO:0002076 17 8 0,000 0,04867676 0,11951489 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04867676 0,1193949 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04867676 0,11927514 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,04867676 0,11915563 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04867676 0,11903635 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04867676 0,11891732 ! response to UV-B GO:0010224 17 8 0,000 0,04867676 0,11879852 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04867676 0,11867996 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04867676 0,11856163 ! intermediate filament organization GO:0045109 12 8 0,000 0,04867676 0,11844354 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04867676 0,11832569 ! cellular extravasation GO:0045123 13 8 0,000 0,04867676 0,11820807 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04867676 0,11809068 ! response to antibiotic GO:0046677 11 8 0,000 0,04867676 0,11797353 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04867676 0,11785661 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04867676 0,11773992 ! DNA topological change GO:0006265 12 8 0,000 0,04867676 0,11762346 ! response to tropane GO:0014073 15 8 0,000 0,04867676 0,11750723 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04867676 0,11739123 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04867676 0,11727546 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04867676 0,11715992 ! mast cell activation GO:0045576 14 8 0,000 0,04867676 0,1170446 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04867676 0,11692951 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04867676 0,11681465 ! gas homeostasis GO:0033483 14 8 0,000 0,04867676 0,11670002 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04867676 0,1165856 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04867676 0,11647142 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04867676 0,11635745 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04867676 0,11624371 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04867676 0,11613019 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04867676 0,11601689 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04867676 0,11590382 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04867676 0,11579096 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04867676 0,11567832 ! response to tumor cell GO:0002347 16 8 0,000 0,04867676 0,1155659 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04867676 0,1154537 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,04867676 0,11534172 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04867676 0,11522996 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,04867676 0,11511841 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04867676 0,11500708 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04867676 0,11489596 ! hormone catabolic process GO:0042447 17 8 0,000 0,04867676 0,11478505 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04867676 0,11467436 GO:0046479|glycosphingolipid catabolic process, ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04867676 0,11456389 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04867676 0,11445362 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04867676 0,11434357 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04867676 0,11423373 ! adult feeding behavior GO:0008343 10 8 0,000 0,04867676 0,1141241 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04867676 0,11401468 ! ATP catabolic process GO:0006200 11 8 0,000 0,04867676 0,11390548 ! blastocyst growth GO:0001832 19 8 0,000 0,04867676 0,11379647 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04867676 0,11368768 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04867676 0,1135791 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04867676 0,11347072 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04867676 0,11336255 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04867676 0,11325459 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04867676 0,11314683 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04867676 0,11303927 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04867676 0,11293192 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04867676 0,11282478 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04867676 0,11271784 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04867676 0,11261109 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04867676 0,11250456 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04867676 0,11239822 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04867676 0,11229208 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04867676 0,11218615 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04867676 0,11208041 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,04867676 0,11197487 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,04867676 0,11186954 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,04912954 0,112804 ! regulation of actin filament length GO:0030832 118 58 1,000 0,05068097 0,11625691 ! aging GO:0007568 112 58 1,000 0,05068097 0,11614785 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,05068097 0,116039 ! lipid modification GO:0030258 112 60 1,000 0,05383599 0,1231473 ! adult behavior GO:0030534 104 60 1,000 0,05383599 0,1230321 ! kidney development GO:0001822 133 60 1,000 0,05383599 0,12291712 ! axon extension GO:0048675 16 9 0,000 0,05459308 0,12452931 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,05459308 0,12441315 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,05459308 0,1242972 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,05459308 0,12418146 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05459308 0,12406595 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,05459308 0,12395064 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,05459308 0,12383555 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,05459308 0,12372068 ! reproductive behavior GO:0019098 22 9 0,000 0,05459308 0,12360602 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05459308 0,12349157 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,05459308 0,12337733 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,05459308 0,1232633 ! RNA methylation GO:0001510 16 9 0,000 0,05459308 0,12314948 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,05459308 0,12303588 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,05459308 0,12292248 ! artery development GO:0060840 25 9 0,000 0,05459308 0,12280929 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,05459308 0,12269631 ! regulation of glycolysis GO:0006110 20 9 0,000 0,05459308 0,12258354 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,05459308 0,12247098 ! equilibrioception GO:0050957 20 9 0,000 0,05459308 0,12235862 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,05459308 0,12224646 ! chemosensory behavior GO:0007635 21 9 0,000 0,05459308 0,12213452 ! microtubule bundle formation GO:0001578 22 9 0,000 0,05459308 0,12202277 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,05459308 0,12191124 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,05459308 0,1217999 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05459308 0,12168877 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,05459308 0,12157784 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,05459308 0,12146711 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,05459308 0,12135659 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,05459308 0,12124627 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05459308 0,12113614 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05459308 0,12102622 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,05459308 0,12091649 ! protein targeting to ER GO:0045047 25 9 0,000 0,05459308 0,12080697 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,05459308 0,12069764 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,05459308 0,12058851 ! T cell selection GO:0045058 27 9 0,000 0,05459308 0,12047958 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,05459308 0,12037084 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,05459308 0,1202623 ! endosome organization GO:0007032 20 9 0,000 0,05459308 0,12015396 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,05459308 0,12004581 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05459308 0,11993785 ! mannose metabolic process GO:0006013 13 9 0,000 0,05459308 0,11983009 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,05459308 0,11972252 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,05459308 0,11961515 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,05459308 0,11950797 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,05459308 0,11940098 ! receptor clustering GO:0043113 20 9 0,000 0,05459308 0,11929418 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,05459308 0,11918757 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05459308 0,11908115 ! retinol metabolic process GO:0042572 20 9 0,000 0,05459308 0,11897493 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,05459308 0,11886889 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,05459308 0,11876304 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,05459308 0,11865738 ! oligodendrocyte development GO:0014003 11 9 0,000 0,05459308 0,1185519 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05459308 0,11844662 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,05459308 0,11834152 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05459308 0,11823661 ! response to amine stimulus GO:0014075 13 9 0,000 0,05459308 0,11813188 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05459308 0,11802734 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,05459308 0,11792298 ! erythrocyte development GO:0048821 17 9 0,000 0,05459308 0,11781881 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05459308 0,11771482 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,05459308 0,11761102 ! renal water homeostasis GO:0003091 15 9 0,000 0,05459308 0,11750739 ! postreplication repair GO:0006301 25 9 0,000 0,05459308 0,11740395 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,05459308 0,1173007 ! icosanoid secretion GO:0032309 15 9 0,000 0,05459308 0,11719762 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05459308 0,11709473 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,05459308 0,11699201 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,05459308 0,11688948 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,05459308 0,11678712 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05459308 0,11668494 ! sterol catabolic process GO:0016127 14 9 0,000 0,05459308 0,11658295 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05459308 0,11648113 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,05459308 0,11637949 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,05459308 0,11627802 ! S phase GO:0051320 10 9 0,000 0,05459308 0,11617674 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,05459308 0,11607562 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,05459308 0,11597469 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,05459308 0,11587393 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,05459308 0,11577334 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05459308 0,11567293 ! purine base metabolic process GO:0006144 25 9 0,000 0,05459308 0,1155727 ! pigment granule transport GO:0051904 17 9 0,000 0,05459308 0,11547263 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,05459308 0,11537274 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,05459308 0,11527303 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,05459308 0,11517348 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05459308 0,11507411 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,05459308 0,11497491 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,05459308 0,11487588 ! mitochondrion localization GO:0051646 18 9 0,000 0,05459308 0,11477702 ! regulation of cellular component size GO:0032535 125 61 1,000 0,05543902 0,11645532 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,05543902 0,11635527 ! regulation of heart contraction GO:0008016 123 61 1,000 0,05543902 0,11625539 ! negative regulation of response to stimulus GO:0048585 106 61 1,000 0,05543902 0,11615569 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,05869481 0,12287182 ! water-soluble vitamin metabolic process GO:0006767 107 63 1,000 0,05869481 0,12276662 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,06034702 0,12611443 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 0,06034702 0,12600664 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 0,06034702 0,12589903 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,06047277 0,12605374 ! regulation of developmental growth GO:0048638 16 10 0,000 0,06047277 0,12594628 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,06047277 0,125839 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06047277 0,1257319 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,06047277 0,12562499 ! associative learning GO:0008306 21 10 0,000 0,06047277 0,12551825 ! phosphate transport GO:0006817 24 10 0,000 0,06047277 0,1254117 ! cell volume homeostasis GO:0006884 17 10 0,000 0,06047277 0,12530533 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,06047277 0,12519914 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,06047277 0,12509313 ! elastic fiber assembly GO:0048251 17 10 0,000 0,06047277 0,1249873 ! social behavior GO:0035176 29 10 0,000 0,06047277 0,12488164 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,06047277 0,12477617 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,06047277 0,12467087 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,06047277 0,12456575 ! androgen metabolic process GO:0008209 17 10 0,000 0,06047277 0,12446081 ! phospholipid efflux GO:0033700 19 10 0,000 0,06047277 0,12435605 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,06047277 0,12425146 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,06047277 0,12414705 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,06047277 0,12404281 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,06047277 0,12393875 ! lung alveolus development GO:0048286 26 10 0,000 0,06047277 0,12383486 ! pathogenesis GO:0009405 17 10 0,000 0,06047277 0,12373114 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06047277 0,1236276 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,06047277 0,12352423 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,06047277 0,12342104 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,06047277 0,12331802 ! endoderm development GO:0007492 18 10 0,000 0,06047277 0,12321517 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,06047277 0,12311249 ! arginine catabolic process GO:0006527 17 10 0,000 0,06047277 0,12300998 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06047277 0,12290764 ! proline metabolic process GO:0006560 13 10 0,000 0,06047277 0,12280547 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,06047277 0,12270348 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,06047277 0,12260165 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,06047277 0,12249999 ! V(D)J recombination GO:0033151 34 10 0,000 0,06047277 0,1223985 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,06047277 0,12229717 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,06047277 0,12219602 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,06047277 0,12209503 ! B cell proliferation GO:0042100 19 10 0,000 0,06047277 0,12199421 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,06047277 0,12189355 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,06047277 0,12179306 ! multicellular organism growth GO:0035264 19 10 0,000 0,06047277 0,12169274 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,06047277 0,12159258 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,06047277 0,12149259 ! ruffle organization GO:0031529 17 10 0,000 0,06047277 0,12139276 ! epithelial cell development GO:0002064 21 10 0,000 0,06047277 0,12129309 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,06047277 0,12119359 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06047277 0,12109425 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,06047277 0,12099507 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,06047277 0,12089606 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,06047277 0,12079721 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,06047277 0,12069852 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,06047277 0,12059999 ! motor axon guidance GO:0008045 22 10 0,000 0,06047277 0,12050162 ! copper ion homeostasis GO:0055070 13 10 0,000 0,06047277 0,12040341 ! regulation of bone resorption GO:0045124 25 10 0,000 0,06047277 0,12030536 ! protein heterooligomerization GO:0051291 17 10 0,000 0,06047277 0,12020747 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,06047277 0,12010974 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,06047277 0,12001217 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,06047277 0,11991476 ! segment specification GO:0007379 15 10 0,000 0,06047277 0,11981751 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,06047277 0,11972041 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,06047277 0,11962347 ! blastoderm segmentation GO:0007350 19 10 0,000 0,06047277 0,11952669 ! response to dsRNA GO:0043331 23 10 0,000 0,06047277 0,11943006 ! DNA ligation GO:0006266 18 10 0,000 0,06047277 0,11933359 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,06047277 0,11923728 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06047277 0,11914112 ! melanosome localization GO:0032400 16 10 0,000 0,06047277 0,11904511 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,06047277 0,11894926 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,06047277 0,11885357 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,06047277 0,11875803 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06047277 0,11866264 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,06047277 0,1185674 ! induction of an organ GO:0001759 17 10 0,000 0,06047277 0,11847232 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,06047277 0,11837739 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,06047277 0,11828261 ! protein sumoylation GO:0016925 17 10 0,000 0,06047277 0,11818799 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,06047277 0,11809351 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06047277 0,11799919 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06047277 0,11790502 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06047277 0,11781099 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,06047277 0,11771712 ! salivary gland development GO:0007431 28 10 0,000 0,06047277 0,1176234 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,06047277 0,11752982 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,06047277 0,11743639 ! midbrain development GO:0030901 14 10 0,000 0,06047277 0,11734312 ! musculoskeletal movement GO:0050881 16 10 0,000 0,06047277 0,11724999 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,06047277 0,11715701 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,06047277 0,11706417 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,06047277 0,11697148 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06047277 0,11687894 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06047277 0,11678655 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,06047277 0,1166943 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,06047277 0,1166022 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,06047277 0,11651024 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06047277 0,11641843 ! blastocyst formation GO:0001825 18 10 0,000 0,06047277 0,11632676 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,06047277 0,11623524 ! cerebellar cortex development GO:0021695 16 10 0,000 0,06047277 0,11614386 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,06047277 0,11605262 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,06047277 0,11596153 ! response to nicotine GO:0035094 20 10 0,000 0,06047277 0,11587058 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,06047277 0,11577977 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 0,0620151 0,11863969 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,0620151 0,11854686 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 127 67 1,000 0,06539782 0,12491546 ! secondary metabolic process GO:0019748 125 67 1,000 0,06539782 0,12481787 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,06631606 0,12647162 ! respiratory burst GO:0045730 17 11 0,000 0,06631606 0,12637297 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,06631606 0,12627447 ! neuron fate specification GO:0048665 18 11 0,000 0,06631606 0,12617613 ! telencephalon cell migration GO:0022029 23 11 0,000 0,06631606 0,12607793 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,06631606 0,1259799 ! synapsis GO:0007129 14 11 0,000 0,06631606 0,12588201 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,06631606 0,12578427 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,06631606 0,12568669 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,06631606 0,12558926 ! response to pain GO:0048265 27 11 0,000 0,06631606 0,12549198 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,06631606 0,12539485 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,06631606 0,12529787 ! blood vessel remodeling GO:0001974 30 11 0,000 0,06631606 0,12520104 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,06631606 0,12510436 ! bone resorption GO:0045453 16 11 0,000 0,06631606 0,12500783 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,06631606 0,12491145 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06631606 0,12481521 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06631606 0,12471913 ! melanocyte differentiation GO:0030318 20 11 0,000 0,06631606 0,12462319 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,06631606 0,1245274 GO:0009075|histidine family amino acid metabolic process, ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,06631606 0,12443176 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,06631606 0,12433626 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,06631606 0,12424091 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,06631606 0,12414571 ! UV protection GO:0009650 20 11 0,000 0,06631606 0,12405065 ! adult heart development GO:0007512 16 11 0,000 0,06631606 0,12395573 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,06631606 0,12386097 ! macroautophagy GO:0016236 19 11 0,000 0,06631606 0,12376635 ! temperature homeostasis GO:0001659 18 11 0,000 0,06631606 0,12367187 ! behavioral fear response GO:0001662 27 11 0,000 0,06631606 0,12357753 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,06631606 0,12348334 ! negative regulation of ossification GO:0030279 27 11 0,000 0,06631606 0,1233893 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,06631606 0,12329539 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,06631606 0,12320163 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,06631606 0,12310801 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,06631606 0,12301454 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,06631606 0,1229212 ! regulation of organ growth GO:0046620 14 11 0,000 0,06631606 0,12282801 ! pigment granule localization GO:0051875 20 11 0,000 0,06631606 0,12273496 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,06631606 0,12264205 ! vasoconstriction GO:0042310 20 11 0,000 0,06631606 0,12254928 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06631606 0,12245665 ! embryonic axis specification GO:0000578 19 11 0,000 0,06631606 0,12236416 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,06631606 0,12227181 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06631606 0,1221796 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,06631606 0,12208752 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06631606 0,12199559 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,06631606 0,1219038 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,06631606 0,12181214 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,06631606 0,12172062 ! prophase GO:0051324 17 11 0,000 0,06631606 0,12162924 ! neuroblast proliferation GO:0007405 25 11 0,000 0,06631606 0,12153799 ! nucleosome positioning GO:0016584 15 11 0,000 0,06631606 0,12144689 ! regulation of isotype switching GO:0045191 24 11 0,000 0,06631606 0,12135591 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,06631606 0,12126508 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,06631606 0,12117438 ! apical protein localization GO:0045176 18 11 0,000 0,06631606 0,12108382 ! acid secretion GO:0046717 20 11 0,000 0,06631606 0,12099339 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06631606 0,12090309 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,06631606 0,12081293 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,06631606 0,12072291 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,06631606 0,12063302 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,06631606 0,12054326 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,06631606 0,12045364 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,06631606 0,12036415 ! cholesterol efflux GO:0033344 21 11 0,000 0,06631606 0,12027479 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06631606 0,12018557 ! oocyte development GO:0048599 20 11 0,000 0,06631606 0,12009648 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,06631606 0,12000752 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,06631606 0,11991869 ! embryonic gut development GO:0048566 19 11 0,000 0,06631606 0,11982999 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,06631606 0,11974142 ! activation of innate immune response GO:0002218 16 11 0,000 0,06631606 0,11965299 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,06631606 0,11956468 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,06631606 0,11947651 ! lysogeny GO:0030069 22 11 0,000 0,06631606 0,11938846 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06631606 0,11930055 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,06631606 0,11921276 ! sequestering of metal ion GO:0051238 15 11 0,000 0,06631606 0,11912511 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,06711195 0,1204662 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,06711195 0,12037775 ! hexose catabolic process GO:0019320 113 68 1,000 0,06711195 0,12028943 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,06711195 0,12020124 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of T cell activation GO:0050870 124 68 1,000 0,06711195 0,12011318 ! regulation of lipase activity GO:0060191 137 68 1,000 0,06711195 0,12002525 ! adaptive immune response GO:0002250 126 68 1,000 0,06711195 0,11993745 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! lung development GO:0030324 165 69 1,000 0,06884093 0,12293742 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,06884093 0,12284761 ! urogenital system development GO:0001655 149 69 1,000 0,06884093 0,12275794 ! cell redox homeostasis GO:0045454 114 70 1,000 0,0705845 0,1257753 ! activation of immune response GO:0002253 120 70 1,000 0,0705845 0,12568362 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 0,0705845 0,12559208 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,07212318 0,12823648 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,07212318 0,12814322 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,07212318 0,12805009 ! virus-host interaction GO:0019048 30 12 0,000 0,07212318 0,1279571 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,07212318 0,12786424 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,07212318 0,12777152 ! protein complex disassembly GO:0043241 28 12 0,000 0,07212318 0,12767893 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,07212318 0,12758648 ! hippocampus development GO:0021766 29 12 0,000 0,07212318 0,12749416 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,07212318 0,12740197 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,07212318 0,12730992 ! T cell proliferation GO:0042098 32 12 0,000 0,07212318 0,12721799 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07212318 0,12712621 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,07212318 0,12703455 ! ventral spinal cord development GO:0021517 25 12 0,000 0,07212318 0,12694303 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,07212318 0,12685164 ! drug transport GO:0015893 16 12 0,000 0,07212318 0,12676038 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,07212318 0,12666925 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,07212318 0,12657825 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,07212318 0,12648738 ! polyamine metabolic process GO:0006595 18 12 0,000 0,07212318 0,12639664 ! focal adhesion formation GO:0048041 37 12 0,000 0,07212318 0,12630604 ! mitotic spindle organization GO:0007052 23 12 0,000 0,07212318 0,12621556 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,07212318 0,12612521 ! forebrain cell migration GO:0021885 24 12 0,000 0,07212318 0,12603499 ! lipid digestion GO:0044241 21 12 0,000 0,07212318 0,12594491 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,07212318 0,12585494 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07212318 0,12576511 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,07212318 0,12567541 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,07212318 0,12558583 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07212318 0,12549638 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,07212318 0,12540706 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,07212318 0,12531787 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,07212318 0,1252288 ! snRNA metabolic process GO:0016073 30 12 0,000 0,07212318 0,12513986 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,07212318 0,12505105 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,07212318 0,12496236 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07212318 0,12487379 ! cranial nerve development GO:0021545 23 12 0,000 0,07212318 0,12478536 ! fucose catabolic process GO:0019317 25 12 0,000 0,07212318 0,12469704 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,07212318 0,12460886 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,07212318 0,12452079 ! autonomic nervous system development GO:0048483 24 12 0,000 0,07212318 0,12443286 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,07212318 0,12434504 ! zymogen activation GO:0031638 18 12 0,000 0,07212318 0,12425735 ! T cell homeostasis GO:0043029 28 12 0,000 0,07212318 0,12416978 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,07212318 0,12408234 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,07212318 0,12399502 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,07212318 0,12390782 ! oocyte differentiation GO:0009994 21 12 0,000 0,07212318 0,12382075 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,07212318 0,12373379 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,07212318 0,12364696 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,07212318 0,12356025 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,07212318 0,12347367 ! developmental induction GO:0031128 22 12 0,000 0,07212318 0,1233872 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,07212318 0,12330086 ! lamellipodium assembly GO:0030032 24 12 0,000 0,07212318 0,12321463 ! response to cold GO:0009409 17 12 0,000 0,07212318 0,12312853 ! regulation of synapse organization GO:0050807 18 12 0,000 0,07212318 0,12304254 ! localization within membrane GO:0051668 26 12 0,000 0,07212318 0,12295668 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,07234242 0,12324444 ! respiratory tube development GO:0030323 171 72 1,000 0,07411444 0,12617532 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,07411444 0,12608746 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,07411444 0,12599971 ! coenzyme biosynthetic process GO:0009108 119 72 1,000 0,07411444 0,12591209 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,07411444 0,12582459 ! humoral immune response GO:0006959 115 73 1,000 0,07590033 0,12876703 ! regulation of immune effector process GO:0002697 156 73 1,000 0,07590033 0,12867767 ! acute inflammatory response GO:0002526 118 74 1,000 0,07769985 0,13163712 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 0,07769985 0,1315459 ! respiratory system development GO:0060541 175 74 1,000 0,07769985 0,1314548 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,07789434 0,13169264 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07789434 0,13160156 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,07789434 0,13151062 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07789434 0,13141979 ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,07789434 0,1313291 ! peroxisomal transport GO:0043574 28 13 0,000 0,07789434 0,13123853 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,07789434 0,13114808 ! cartilage condensation GO:0001502 22 13 0,000 0,07789434 0,13105776 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,07789434 0,13096756 ! organelle fusion GO:0048284 36 13 0,000 0,07789434 0,13087748 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,07789434 0,13078753 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,07789434 0,13069771 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,07789434 0,130608 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,07789434 0,13051842 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,07789434 0,13042897 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,07789434 0,13033963 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,07789434 0,13025042 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,07789434 0,13016133 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07789434 0,13007236 ! methionine metabolic process GO:0006555 31 13 0,000 0,07789434 0,12998351 ! plasma membrane organization GO:0007009 27 13 0,000 0,07789434 0,12989479 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,07789434 0,12980618 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,07789434 0,1297177 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,07789434 0,12962933 ! response to X-ray GO:0010165 28 13 0,000 0,07789434 0,12954109 ! cytokine metabolic process GO:0042107 24 13 0,000 0,07789434 0,12945297 ! exocrine system development GO:0035272 34 13 0,000 0,07789434 0,12936496 ! asymmetric protein localization GO:0008105 24 13 0,000 0,07789434 0,12927708 ! monoamine transport GO:0015844 21 13 0,000 0,07789434 0,12918932 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,07789434 0,12910167 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,07789434 0,12901414 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,07789434 0,12892674 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,07789434 0,12883945 ! protein homotetramerization GO:0051289 24 13 0,000 0,07789434 0,12875227 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,07789434 0,12866522 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,07789434 0,12857828 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,07789434 0,12849147 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,07789434 0,12840476 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,07789434 0,12831818 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,07789434 0,12823171 ! histone methylation GO:0016571 29 13 0,000 0,07789434 0,12814536 ! chromatin silencing GO:0006342 29 13 0,000 0,07789434 0,12805913 ! gland morphogenesis GO:0022612 31 13 0,000 0,07789434 0,12797301 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,07789434 0,127887 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,07789434 0,12780112 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,07789434 0,12771534 ! spleen development GO:0048536 24 13 0,000 0,07789434 0,12762969 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,07789434 0,12754414 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,07789434 0,12745871 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,07789434 0,1273734 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,07789434 0,1272882 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07789434 0,12720312 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,07789434 0,12711814 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,07789434 0,12703329 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,07789434 0,12694854 ! insulin secretion GO:0030073 24 13 0,000 0,07789434 0,12686391 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,07789434 0,12677939 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,07789434 0,12669498 ! acrosome reaction GO:0007340 19 13 0,000 0,07789434 0,12661069 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,07789434 0,1265265 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,07789434 0,12644243 ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,07951275 0,12898383 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 0,08133881 0,13185846 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,08317779 0,13475022 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,08317779 0,13466092 ! monosaccharide catabolic process GO:0046365 125 77 1,000 0,08317779 0,13457174 ! regulation of catabolic process GO:0009894 173 77 1,000 0,08317779 0,13448268 ! rRNA transcription GO:0009303 28 14 0,000 0,08362976 0,13512401 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,08362976 0,1350347 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,08362976 0,13494551 ! water transport GO:0006833 21 14 0,000 0,08362976 0,13485644 GO:0042044|fluid transport, ! non-recombinational repair GO:0000726 29 14 0,000 0,08362976 0,13476748 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,08362976 0,13467864 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,08362976 0,13458992 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,08362976 0,13450132 ! RNA polyadenylation GO:0043631 32 14 0,000 0,08362976 0,13441283 ! lipid localization GO:0010876 32 14 0,000 0,08362976 0,13432446 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,08362976 0,1342362 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,08362976 0,13414806 ! regulated secretory pathway GO:0045055 24 14 0,000 0,08362976 0,13406004 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,08362976 0,13397213 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,08362976 0,13388434 ! arginine metabolic process GO:0006525 21 14 0,000 0,08362976 0,13379666 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,08362976 0,1337091 ! regulation of heart rate GO:0002027 25 14 0,000 0,08362976 0,13362165 ! fear response GO:0042596 34 14 0,000 0,08362976 0,13353432 ! organic alcohol transport GO:0015850 29 14 0,000 0,08362976 0,13344709 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,08362976 0,13335999 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,08362976 0,133273 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,08362976 0,13318612 ! neutral amino acid transport GO:0015804 28 14 0,000 0,08362976 0,13309935 ! bone mineralization GO:0030282 18 14 0,000 0,08362976 0,1330127 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,08362976 0,13292616 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,08362976 0,13283973 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,08362976 0,13275341 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,08362976 0,13266721 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,08362976 0,13258112 ! regulation of cellular pH GO:0030641 27 14 0,000 0,08362976 0,13249514 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,08362976 0,13240927 ! ribosome assembly GO:0042255 18 14 0,000 0,08362976 0,13232351 ! cerebellum development GO:0021549 23 14 0,000 0,08362976 0,13223787 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,08362976 0,13215233 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,08362976 0,13206691 ! response to gamma radiation GO:0010332 30 14 0,000 0,08362976 0,13198159 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,08362976 0,13189639 ! NADP metabolic process GO:0006739 24 14 0,000 0,08362976 0,13181129 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,08362976 0,13172631 ! oxygen transport GO:0015671 22 14 0,000 0,08362976 0,13164143 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08362976 0,13155667 ! male genitalia development GO:0030539 26 14 0,000 0,08362976 0,13147201 ! regulation of RNA stability GO:0043487 33 14 0,000 0,08362976 0,13138746 ! regulation of axon extension GO:0030516 43 14 0,000 0,08362976 0,13130302 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,08362976 0,13121869 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,08362976 0,13113447 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,08362976 0,13105035 ! antigen processing and presentation GO:0019882 117 78 1,000 0,08502946 0,13315831 ! regulation of actin filament-based process GO:0032970 170 79 1,000 0,08689359 0,13599042 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,08876997 0,13883805 ! activation of protein kinase activity GO:0032147 170 80 1,000 0,08876997 0,13874922 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08932967 0,13953477 ! reproductive cellular process GO:0048610 22 15 0,000 0,08932967 0,13944561 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08932967 0,13935657 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,08932967 0,13926763 ! superoxide anion generation GO:0042554 22 15 0,000 0,08932967 0,13917882 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,08932967 0,13909011 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,08932967 0,13900152 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,08932967 0,13891304 ! copper ion transport GO:0006825 22 15 0,000 0,08932967 0,13882467 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,08932967 0,13873642 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,08932967 0,13864827 ! sulfate transport GO:0008272 27 15 0,000 0,08932967 0,13856024 ! response to cAMP GO:0051591 25 15 0,000 0,08932967 0,13847232 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,08932967 0,13838452 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,08932967 0,13829682 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,08932967 0,13820924 ! response to hexose stimulus GO:0009746 25 15 0,000 0,08932967 0,13812176 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,08932967 0,1380344 ! vesicle coating GO:0006901 38 15 0,000 0,08932967 0,13794715 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,08932967 0,13786 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,08932967 0,13777297 ! regulation of exocytosis GO:0017157 26 15 0,000 0,08932967 0,13768605 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,08932967 0,13759923 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,08932967 0,13751253 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,08932967 0,13742593 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,08932967 0,13733945 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,08932967 0,13725307 ! regulation of vasodilation GO:0042312 27 15 0,000 0,08932967 0,1371668 ! histone deacetylation GO:0016575 24 15 0,000 0,08932967 0,13708064 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,08932967 0,13699459 ! water homeostasis GO:0030104 28 15 0,000 0,08932967 0,13690865 ! cofactor transport GO:0051181 30 15 0,000 0,08932967 0,13682281 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08932967 0,13673708 ! muscle maintenance GO:0046716 26 15 0,000 0,08932967 0,13665146 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,08932967 0,13656595 ! intestinal absorption GO:0050892 31 15 0,000 0,08932967 0,13648054 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08932967 0,13639524 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,08932967 0,13631005 ! heme biosynthetic process GO:0006783 33 15 0,000 0,08932967 0,13622496 ! cell killing GO:0001906 32 15 0,000 0,08932967 0,13613998 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,08932967 0,1360551 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,08932967 0,13597033 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,08932967 0,13588567 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,08932967 0,13580111 ! actin filament polymerization GO:0030041 27 15 0,000 0,08932967 0,13571666 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,08932967 0,13563231 ! response to hypoxia GO:0001666 178 81 1,000 0,09065836 0,13756421 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,09065836 0,13747882 ! protein import into nucleus GO:0006606 174 82 1,000 0,09255855 0,14027329 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,09447032 0,14308184 ! response to oxygen levels GO:0070482 183 83 1,000 0,09447032 0,14299318 ! nuclear import GO:0051170 177 83 1,000 0,09447032 0,14290464 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,09499429 0,14360832 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,09499429 0,14351951 ! positive regulation of cell size GO:0045793 29 16 0,000 0,09499429 0,1434308 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,09499429 0,14334221 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,09499429 0,14325373 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,09499429 0,14316536 ! bone remodeling GO:0046849 28 16 0,000 0,09499429 0,14307709 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,09499429 0,14298893 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,09499429 0,14290089 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,09499429 0,14281295 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,09499429 0,14272512 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,09499429 0,14263739 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,09499429 0,14254978 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,09499429 0,14246227 ! startle response GO:0001964 28 16 0,000 0,09499429 0,14237487 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,09499429 0,14228758 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,09499429 0,14220039 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,09499429 0,14211331 ! protein polyubiquitination GO:0000209 41 16 0,000 0,09499429 0,14202634 ! pituitary gland development GO:0021983 30 16 0,000 0,09499429 0,14193947 ! response to osmotic stress GO:0006970 27 16 0,000 0,09499429 0,14185271 ! lysosomal transport GO:0007041 31 16 0,000 0,09499429 0,14176606 ! fructose metabolic process GO:0006000 25 16 0,000 0,09499429 0,14167951 ! L-amino acid transport GO:0015807 33 16 0,000 0,09499429 0,14159307 ! stem cell development GO:0048864 46 16 0,000 0,09499429 0,14150673 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09499429 0,1414205 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 36 16 0,000 0,09499429 0,14133437 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,09499429 0,14124835 ! axon cargo transport GO:0008088 46 16 0,000 0,09499429 0,14116243 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,09499429 0,14107662 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,09499429 0,14099091 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,09499429 0,14090531 ! DNA replication initiation GO:0006270 28 16 0,000 0,09499429 0,14081981 ! neuron recognition GO:0008038 40 16 0,000 0,09499429 0,14073441 ! mRNA splice site selection GO:0006376 44 16 0,000 0,09499429 0,14064912 ! tissue regeneration GO:0042246 27 16 0,000 0,09499429 0,14056393 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,09499429 0,14047884 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,09499429 0,14039385 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,09499429 0,14030897 ! biomineral formation GO:0031214 22 16 0,000 0,09499429 0,14022419 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,09499429 0,14013952 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,09499429 0,14005494 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,09499429 0,13997047 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09499429 0,1398861 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,09499429 0,13980183 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,09499429 0,13971766 ! peptide hormone processing GO:0016486 27 16 0,000 0,09499429 0,1396336 ! response to nutrient GO:0007584 135 84 1,000 0,09639346 0,14160506 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,09832774 0,14435978 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,09832774 0,14427308 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,10027296 0,14703893 ! regulation of lyase activity GO:0051339 169 86 1,000 0,10027296 0,14695072 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,10062383 0,1473765 ! metencephalon development GO:0022037 32 17 0,000 0,10062383 0,1472882 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,10062383 0,1472 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,10062383 0,14711191 ! signal complex assembly GO:0007172 47 17 0,000 0,10062383 0,14702393 ! gene silencing by RNA GO:0031047 38 17 0,000 0,10062383 0,14693605 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,10062383 0,14684827 ! glial cell development GO:0021782 28 17 0,000 0,10062383 0,1467606 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,10062383 0,14667303 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,10062383 0,14658557 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,10062383 0,14649821 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,10062383 0,14641096 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,10062383 0,14632381 ! myoblast differentiation GO:0045445 50 17 0,000 0,10062383 0,14623677 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,10062383 0,14614982 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,10062383 0,14606299 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,10062383 0,14597625 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,10062383 0,14588962 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,10062383 0,14580309 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,10062383 0,14571666 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,10062383 0,14563033 GO:0031114|regulation of microtubule depolymerization, ! membrane budding GO:0006900 42 17 0,000 0,10062383 0,14554411 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,10062383 0,14545799 ! regulation of protein binding GO:0043393 33 17 0,000 0,10062383 0,14537197 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,10062383 0,14528605 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,10062383 0,14520024 ! genitalia development GO:0048806 32 17 0,000 0,10062383 0,14511452 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,10062383 0,14502891 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,10062383 0,1449434 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,10062383 0,14485799 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,10062383 0,14477268 ! steroid catabolic process GO:0006706 34 17 0,000 0,10062383 0,14468747 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,10062383 0,14460236 ! gas transport GO:0015669 26 17 0,000 0,10062383 0,14451735 ! organic cation transport GO:0015695 32 17 0,000 0,10062383 0,14443244 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,10062383 0,14434762 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,10062383 0,14426291 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,10062383 0,1441783 ! mitochondrion organization GO:0007005 159 87 1,000 0,10222892 0,14639229 ! alcohol catabolic process GO:0046164 142 87 1,000 0,10222892 0,14630653 ! nucleosome assembly GO:0006334 126 87 1,000 0,10222892 0,14622087 ! amine biosynthetic process GO:0009309 146 88 1,000 0,10419539 0,14894637 ! chromatin assembly GO:0031497 128 88 1,000 0,10419539 0,14885926 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,10617218 0,15159477 ! protein localization in nucleus GO:0034504 192 89 1,000 0,10617218 0,15150622 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,1062185 0,15148383 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,1062185 0,15139545 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,1062185 0,15130717 ! limbic system development GO:0021761 40 18 0,000 0,1062185 0,151219 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,1062185 0,15113093 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,1062185 0,15104296 ! adult walking behavior GO:0007628 36 18 0,000 0,1062185 0,15095509 ! patterning of blood vessels GO:0001569 43 18 0,000 0,1062185 0,15086733 ! heart looping GO:0001947 34 18 0,000 0,1062185 0,15077967 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,1062185 0,1506921 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,1062185 0,15060465 ! centrosome cycle GO:0007098 26 18 0,000 0,1062185 0,15051729 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,1062185 0,15043003 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,1062185 0,15034288 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,1062185 0,15025582 ! glutamine metabolic process GO:0006541 29 18 0,000 0,1062185 0,15016887 ! response to retinoic acid GO:0032526 31 18 0,000 0,1062185 0,15008201 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,1062185 0,14999526 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,1062185 0,14990861 ! DNA integration GO:0015074 32 18 0,000 0,1062185 0,14982206 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,1062185 0,14973561 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,1062185 0,14964925 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,1062185 0,149563 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,1062185 0,14947685 ! neural crest cell migration GO:0001755 41 18 0,000 0,1062185 0,14939079 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,1062185 0,14930484 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,1062185 0,14921898 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,1062185 0,14913322 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,1062185 0,14904756 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,1062185 0,148962 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,1062185 0,14887654 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,1062185 0,14879117 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,1062185 0,1487059 ! nerve development GO:0021675 34 18 0,000 0,1062185 0,14862074 ! defense response to virus GO:0051607 43 18 0,000 0,1062185 0,14853566 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,1062185 0,14845069 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,1062185 0,14836581 ! defense response to bacterium GO:0042742 112 91 1,000 0,11015591 0,15377765 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,11015591 0,15368983 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,11177854 0,1558647 ! positive regulation of translation GO:0045727 31 19 0,000 0,11177854 0,15577579 ! negative regulation of defense response GO:0031348 27 19 0,000 0,11177854 0,15568698 ! neuron maturation GO:0042551 46 19 0,000 0,11177854 0,15559827 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,11177854 0,15550966 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,11177854 0,15542115 ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,11177854 0,15533274 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,11177854 0,15524444 ! inositol metabolic process GO:0006020 33 19 0,000 0,11177854 0,15515623 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,11177854 0,15506812 ! memory GO:0007613 34 19 0,000 0,11177854 0,15498012 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,11177854 0,15489221 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,11177854 0,1548044 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,11177854 0,15471669 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,11177854 0,15462908 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,11177854 0,15454157 ! cerebral cortex development GO:0021987 40 19 0,000 0,11177854 0,15445416 ! pigmentation during development GO:0048066 42 19 0,000 0,11177854 0,15436685 ! response to vitamin A GO:0033189 32 19 0,000 0,11177854 0,15427964 ! heme metabolic process GO:0042168 40 19 0,000 0,11177854 0,15419253 ! neuromuscular junction development GO:0007528 43 19 0,000 0,11177854 0,15410551 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,11177854 0,15401859 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,11177854 0,15393177 ! peptide cross-linking GO:0018149 39 19 0,000 0,11177854 0,15384505 ! protein export from nucleus GO:0006611 40 19 0,000 0,11177854 0,15375843 ! heart process GO:0003015 32 19 0,000 0,11177854 0,1536719 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,11177854 0,15358547 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,11177854 0,15349914 ! visual learning GO:0008542 38 19 0,000 0,11177854 0,1534129 ! cellular pigmentation GO:0033059 37 19 0,000 0,11177854 0,15332676 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,11177854 0,15324072 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,11177854 0,15315477 ! vitamin transport GO:0051180 31 19 0,000 0,11177854 0,15306893 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,11177854 0,15298317 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,11177854 0,15289752 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,11177854 0,15281195 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,11177854 0,15272649 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,11177854 0,15264112 ! cilium assembly GO:0042384 38 19 0,000 0,11177854 0,15255585 ! peptide hormone secretion GO:0030072 32 19 0,000 0,11177854 0,15247067 ! protein-DNA complex assembly GO:0065004 134 92 1,000 0,11216244 0,15290896 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,1141785 0,15557059 GO:0010498|proteasomal protein catabolic process, ! vitamin metabolic process GO:0006766 153 93 1,000 0,1141785 0,15548387 ! protein secretion GO:0009306 45 20 0,000 0,11730414 0,15965126 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,11730414 0,15956236 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,11730414 0,15947357 ! positive regulation of ossification GO:0045778 50 20 0,000 0,11730414 0,15938487 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,11730414 0,15929628 ! skin development GO:0043588 42 20 0,000 0,11730414 0,15920778 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,11730414 0,15911938 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,11730414 0,15903108 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,11730414 0,15894288 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,11730414 0,15885477 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,11730414 0,15876676 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,11730414 0,15867885 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,11730414 0,15859104 ! bile acid metabolic process GO:0008206 34 20 0,000 0,11730414 0,15850332 ! response to alkaloid GO:0043279 38 20 0,000 0,11730414 0,1584157 ! retinoid metabolic process GO:0001523 34 20 0,000 0,11730414 0,15832818 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,11730414 0,15824075 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,11730414 0,15815342 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,11730414 0,15806619 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,11730414 0,15797905 ! actin filament bundle formation GO:0051017 47 20 0,000 0,11730414 0,15789201 ! body fluid secretion GO:0007589 33 20 0,000 0,11730414 0,15780507 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,11730414 0,15771822 ! peptide secretion GO:0002790 38 20 0,000 0,11730414 0,15763147 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,11730414 0,15754481 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,11730414 0,15745824 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,11730414 0,15737178 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,11730414 0,1572854 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,11730414 0,15719912 ! cell-cell junction organization GO:0045216 43 20 0,000 0,11730414 0,15711294 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,11730414 0,15702685 ! regulation of glucose import GO:0046324 30 20 0,000 0,11730414 0,15694086 GO:0010827|regulation of glucose transport, ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,11730414 0,15685496 ! negative regulation of translation GO:0017148 32 20 0,000 0,11730414 0,15676915 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,11730414 0,15668344 ! nucleosome organization GO:0034728 143 95 1,000 0,11823838 0,15784501 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,11823838 0,15775881 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 0,12233404 0,16313431 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,12233404 0,16304531 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,12279552 0,16357113 ! hormone secretion GO:0046879 39 21 0,000 0,12279552 0,16348199 ! cAMP metabolic process GO:0046058 41 21 0,000 0,12279552 0,16339294 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,12279552 0,163304 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,12279552 0,16321515 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,12279552 0,1631264 ! ovarian follicle development GO:0001541 39 21 0,000 0,12279552 0,16303774 ! smooth muscle contraction GO:0006939 48 21 0,000 0,12279552 0,16294918 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,12279552 0,16286072 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,12279552 0,16277235 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,12279552 0,16268408 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,12279552 0,16259591 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,12279552 0,16250783 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,12279552 0,16241984 ! sensory perception of pain GO:0019233 33 21 0,000 0,12279552 0,16233195 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,12279552 0,16224416 ! diencephalon development GO:0021536 36 21 0,000 0,12279552 0,16215646 ! collagen fibril organization GO:0030199 62 21 0,000 0,12279552 0,16206885 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,12279552 0,16198134 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,12279552 0,16189393 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,12279552 0,1618066 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,12279552 0,16171938 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,12279552 0,16163224 ! collagen catabolic process GO:0030574 29 21 0,000 0,12279552 0,1615452 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,12279552 0,16145826 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,12279552 0,16137141 ! sperm-egg recognition GO:0035036 23 21 0,000 0,12279552 0,16128465 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,12279552 0,16119798 ! forebrain development GO:0030900 210 98 1,000 0,12439481 0,16320973 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,12439481 0,16312212 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,12825289 0,1680911 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,12825289 0,16800097 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,12825289 0,16791093 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,12825289 0,167821 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,12825289 0,16773116 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,12825289 0,16764141 ! microtubule-based transport GO:0010970 59 22 0,000 0,12825289 0,16755177 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,12825289 0,16746221 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,12825289 0,16737276 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,12825289 0,1672834 ! cellular response to starvation GO:0009267 37 22 0,000 0,12825289 0,16719413 ! vacuolar transport GO:0007034 41 22 0,000 0,12825289 0,16710496 ! central nervous system neuron development GO:0021954 47 22 0,000 0,12825289 0,16701589 ! fucose metabolic process GO:0006004 44 22 0,000 0,12825289 0,16692691 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,12825289 0,16683802 ! ureteric bud development GO:0001657 50 22 0,000 0,12825289 0,16674923 ! cell aging GO:0007569 48 22 0,000 0,12825289 0,16666053 ! stem cell differentiation GO:0048863 57 22 0,000 0,12825289 0,16657193 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,12825289 0,16648342 ! cytolysis GO:0019835 27 22 0,000 0,12825289 0,16639501 ! renal system process GO:0003014 42 22 0,000 0,12825289 0,16630669 ! vasodilation GO:0042311 40 22 0,000 0,12825289 0,16621846 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,12825289 0,16613033 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,12825289 0,16604229 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,12825289 0,16595434 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,12825289 0,16586649 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,12825289 0,16577873 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,12825289 0,16569106 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,12825289 0,16560349 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,12825289 0,16551601 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,12825289 0,16542862 ! sarcomere organization GO:0045214 32 22 0,000 0,12825289 0,16534132 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,12825289 0,16525412 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,12825289 0,165167 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,12825289 0,16507998 ! gut development GO:0048565 44 22 0,000 0,12825289 0,16499305 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,12825289 0,16490621 ! protein stabilization GO:0050821 41 22 0,000 0,12825289 0,16481946 ! positive regulation of immune response GO:0050778 175 100 1,000 0,1285413 0,16510326 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,13367646 0,17160882 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,13367646 0,17151869 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,13367646 0,17142866 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,13367646 0,17133871 ! gluconeogenesis GO:0006094 38 23 0,000 0,13367646 0,17124887 ! glycerol metabolic process GO:0006071 40 23 0,000 0,13367646 0,17115911 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,13367646 0,17106945 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,13367646 0,17097989 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,13367646 0,17089042 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,13367646 0,17080104 ! regeneration GO:0031099 42 23 0,000 0,13367646 0,17071176 ! axis specification GO:0009798 43 23 0,000 0,13367646 0,17062256 ! visual behavior GO:0007632 46 23 0,000 0,13367646 0,17053347 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,13367646 0,17044446 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,13367646 0,17035555 ! peroxisome organization GO:0007031 43 23 0,000 0,13367646 0,17026673 ! lysosome organization GO:0007040 47 23 0,000 0,13367646 0,170178 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,13367646 0,17008937 ! vesicle targeting GO:0006903 49 23 0,000 0,13367646 0,17000083 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,13367646 0,16991238 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,13367646 0,16982402 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,13367646 0,16973575 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,13367646 0,16964758 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,13367646 0,1695595 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,13367646 0,1694715 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,13367646 0,1693836 ! hormone transport GO:0009914 41 23 0,000 0,13367646 0,16929579 ! cell-cell recognition GO:0009988 28 23 0,000 0,13367646 0,16920808 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,13367646 0,16912045 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,13367646 0,16903291 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,13367646 0,16894547 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,13906644 0,17566666 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,13906644 0,17557587 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,13906644 0,17548518 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,13906644 0,17539458 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,13906644 0,17530408 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,13906644 0,17521367 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,13906644 0,17512336 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,13906644 0,17503313 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,13906644 0,174943 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,13906644 0,17485297 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,13906644 0,17476302 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,13906644 0,17467317 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,13906644 0,17458341 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,13906644 0,17449374 ! sex determination GO:0007530 48 24 0,000 0,13906644 0,17440416 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,13906644 0,17431468 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,13906644 0,17422529 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,13906644 0,17413599 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,13906644 0,17404678 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,13906644 0,17395766 ! membrane depolarization GO:0051899 45 24 0,000 0,13906644 0,17386863 ! pallium development GO:0021543 56 24 0,000 0,13906644 0,1737797 ! oogenesis GO:0048477 44 24 0,000 0,13906644 0,17369085 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,13906644 0,1736021 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,13906644 0,17351344 ! platelet activation GO:0030168 41 24 0,000 0,13906644 0,17342487 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,13906644 0,17333638 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,13906644 0,17324799 ! regulation of amine transport GO:0051952 41 24 0,000 0,13906644 0,17315969 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,13906644 0,17307148 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,14442304 0,17964637 ! leukocyte adhesion GO:0007159 55 25 0,000 0,14442304 0,17955495 ! phototransduction GO:0007602 37 25 0,000 0,14442304 0,17946362 ! keratinization GO:0031424 37 25 0,000 0,14442304 0,17937238 ! vasculogenesis GO:0001570 49 25 0,000 0,14442304 0,17928124 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,14442304 0,17919019 ! vacuole organization GO:0007033 49 25 0,000 0,14442304 0,17909923 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,14442304 0,17900836 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,14442304 0,17891758 ! receptor metabolic process GO:0043112 53 25 0,000 0,14442304 0,1788269 ! chromosome condensation GO:0030261 48 25 0,000 0,14442304 0,17873631 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,14442304 0,17864581 ! regulation of behavior GO:0050795 48 25 0,000 0,14442304 0,1785554 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,14442304 0,17846509 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,14442304 0,17837486 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,14442304 0,17828473 ! immunoglobulin production GO:0002377 62 25 0,000 0,14442304 0,17819469 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,14442304 0,17810473 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,14442304 0,17801487 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,14442304 0,1779251 ! liver development GO:0001889 55 25 0,000 0,14442304 0,17783542 ! protein tetramerization GO:0051262 57 25 0,000 0,14442304 0,17774583 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,14974645 0,18420473 ! myelination GO:0042552 50 26 0,000 0,14974645 0,18411202 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,14974645 0,18401941 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,14974645 0,18392689 ! molting cycle process GO:0022404 52 26 0,000 0,14974645 0,18383447 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,14974645 0,18374213 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,14974645 0,18364989 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,14974645 0,18355775 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,14974645 0,18346569 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,14974645 0,18337373 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,14974645 0,18328186 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,14974645 0,18319008 ! digestive system process GO:0022600 49 26 0,000 0,14974645 0,18309839 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,14974645 0,1830068 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,14974645 0,18291529 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,14974645 0,18282388 ! osteoblast differentiation GO:0001649 63 26 0,000 0,14974645 0,18273256 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,14974645 0,18264133 ! neural crest cell development GO:0014032 59 26 0,000 0,14974645 0,18255019 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,14974645 0,18245915 ! negative regulation of cell development GO:0010721 83 26 0,000 0,14974645 0,18236819 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,14974645 0,18227732 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,14974645 0,18218655 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! response to estradiol stimulus GO:0032355 43 26 0,000 0,14974645 0,18209586 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,14974645 0,18200527 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,14974645 0,18191476 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,14974645 0,18182435 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,14974645 0,18173402 ! blastocyst development GO:0001824 50 26 0,000 0,14974645 0,18164379 ! telomere organization GO:0032200 46 26 0,000 0,14974645 0,18155364 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 58 26 0,000 0,14974645 0,18146359 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,14974645 0,18137362 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,14974645 0,18128374 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,14974645 0,18119395 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,1550369 0,18750255 ! embryonic pattern specification GO:0009880 49 27 0,000 0,1550369 0,18740977 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,1550369 0,18731709 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,1550369 0,18722449 ! iron ion transport GO:0006826 65 27 0,000 0,1550369 0,18713199 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,1550369 0,18703958 ! superoxide metabolic process GO:0006801 41 27 0,000 0,1550369 0,18694726 ! tube lumen formation GO:0035148 59 27 0,000 0,1550369 0,18685503 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,1550369 0,18676289 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,1550369 0,18667085 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,1550369 0,18657889 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,1550369 0,18648702 ! response to starvation GO:0042594 47 27 0,000 0,1550369 0,18639525 ! response to toxin GO:0009636 49 27 0,000 0,1550369 0,18630356 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,1550369 0,18621197 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,1550369 0,18612047 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,1550369 0,18602905 ! leukocyte proliferation GO:0070661 59 27 0,000 0,1550369 0,18593773 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,16029458 0,19214899 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,16029458 0,19205476 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,16029458 0,19196061 ! vesicle docking GO:0048278 55 28 0,000 0,16029458 0,19186656 ! circadian rhythm GO:0007623 56 28 0,000 0,16029458 0,1917726 ! dendrite development GO:0016358 67 28 0,000 0,16029458 0,19167873 ! fat cell differentiation GO:0045444 57 28 0,000 0,16029458 0,19158495 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,16029458 0,19149127 ! sperm motility GO:0030317 37 28 0,000 0,16029458 0,19139768 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,16029458 0,19130418 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,16029458 0,19121077 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,16029458 0,19111745 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,16029458 0,19102422 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,16029458 0,19093108 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,16029458 0,19083803 ! glutathione metabolic process GO:0006749 42 28 0,000 0,16029458 0,19074508 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,16029458 0,19065221 ! lipid oxidation GO:0034440 48 28 0,000 0,16029458 0,19055944 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,16029458 0,19046675 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,16551968 0,19657977 ! translational initiation GO:0006413 66 29 0,000 0,16551968 0,19648425 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,16551968 0,19638882 ! catechol metabolic process GO:0009712 55 29 0,000 0,16551968 0,19629349 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,16551968 0,19619825 ! autophagy GO:0006914 47 29 0,000 0,16551968 0,1961031 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,16551968 0,19600804 ! primary neural tube formation GO:0014020 61 29 0,000 0,16551968 0,19591307 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,16551968 0,1958182 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,16551968 0,19572342 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,16551968 0,19562873 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,16551968 0,19553413 ! synaptogenesis GO:0007416 46 29 0,000 0,16551968 0,19543962 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,16551968 0,19534521 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,16551968 0,19525089 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,16551968 0,19515665 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,16551968 0,19506251 ! phenol metabolic process GO:0018958 56 30 0,000 0,17071242 0,20108508 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,17071242 0,20098817 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,17071242 0,20089135 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,17071242 0,20079463 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,17071242 0,200698 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,17071242 0,20060147 ! acute-phase response GO:0006953 50 30 0,000 0,17071242 0,20050502 ! myofibril assembly GO:0030239 50 30 0,000 0,17071242 0,20040867 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,17071242 0,20031241 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,17071242 0,20021625 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,17071242 0,20012018 ! cell fate determination GO:0001709 64 30 0,000 0,17071242 0,20002419 ! phospholipid transport GO:0015914 65 30 0,000 0,17071242 0,19992831 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,17071242 0,19983251 ! neurotransmitter secretion GO:0007269 55 30 0,000 0,17071242 0,1997368 ! tissue homeostasis GO:0001894 50 30 0,000 0,17071242 0,19964119 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,17071242 0,19954567 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,17587299 0,20547954 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,17587299 0,20538132 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,17587299 0,20528319 ! cell junction assembly GO:0034329 85 31 0,000 0,17587299 0,20518516 ! regulation of innate immune response GO:0045088 57 31 0,000 0,17587299 0,20508722 ! ovulation cycle process GO:0022602 55 31 0,000 0,17587299 0,20498937 ! peptide transport GO:0015833 60 31 0,000 0,17587299 0,20489162 ! male gonad development GO:0008584 56 31 0,000 0,17587299 0,20479396 ! iron ion homeostasis GO:0055072 60 31 0,000 0,17587299 0,20469639 ! detection of light stimulus GO:0009583 44 31 0,000 0,17587299 0,20459892 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,17587299 0,20450153 ! natural killer cell activation GO:0030101 50 31 0,000 0,17587299 0,20440425 ! ensheathment of neurons GO:0007272 64 31 0,000 0,17587299 0,20430705 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,17587299 0,20420994 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,17587299 0,20411293 ! eye morphogenesis GO:0048592 65 31 0,000 0,17587299 0,20401601 ! response to heat GO:0009408 54 31 0,000 0,17587299 0,20391919 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,17587299 0,20382245 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,1810016 0,20966662 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,1810016 0,20956725 ! collagen metabolic process GO:0032963 49 32 0,000 0,1810016 0,20946798 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,1810016 0,2093688 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,1810016 0,20926971 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,1810016 0,20917072 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,1810016 0,20907182 ! muscle cell development GO:0055001 52 32 0,000 0,1810016 0,20897302 ! mesoderm formation GO:0001707 73 32 0,000 0,1810016 0,2088743 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,1810016 0,20877568 ! ovulation cycle GO:0042698 57 32 0,000 0,1810016 0,20867716 ! peripheral nervous system development GO:0007422 68 32 0,000 0,1810016 0,20857873 ! BMP signaling pathway GO:0030509 71 32 0,000 0,1810016 0,20848039 ! hindbrain development GO:0030902 65 32 0,000 0,1810016 0,20838214 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,1810016 0,20828398 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,1810016 0,20818592 ! gene silencing GO:0016458 71 32 0,000 0,1810016 0,20808795 ! regulation of pH GO:0006885 56 33 0,000 0,18609843 0,21384688 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,18609843 0,21374634 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,18609843 0,21364589 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,18609843 0,21354554 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,18609843 0,21344529 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,18609843 0,21334512 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,18609843 0,21324505 ! response to ionizing radiation GO:0010212 74 33 0,000 0,18609843 0,21314508 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,18609843 0,2130452 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,18609843 0,21294541 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,18609843 0,21284572 GO:0060326|cell chemotaxis, ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,18609843 0,21274612 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,18609843 0,21264661 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,18609843 0,2125472 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,19116368 0,21823031 ! glial cell differentiation GO:0010001 67 34 0,000 0,19116368 0,21812839 ! post-embryonic development GO:0009791 76 34 0,000 0,19116368 0,21802655 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,19116368 0,21792481 ! cholesterol transport GO:0030301 62 34 0,000 0,19116368 0,21782317 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,19116368 0,21772162 ! spliceosome assembly GO:0000245 75 34 0,000 0,19116368 0,21762016 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,19116368 0,2175188 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,19116368 0,21741754 ! formation of primary germ layer GO:0001704 76 34 0,000 0,19116368 0,21731637 ! cell fate specification GO:0001708 56 34 0,000 0,19116368 0,21721529 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,19116368 0,21711431 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,19619755 0,22272799 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,19619755 0,22262454 ! negative regulation of secretion GO:0051048 68 35 0,000 0,19619755 0,22252118 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,19619755 0,22241792 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,19619755 0,22231476 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,19619755 0,22221169 ! membrane docking GO:0022406 69 35 0,000 0,19619755 0,22210872 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,19619755 0,22200585 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,19619755 0,22190307 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,19619755 0,22180038 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,19619755 0,22169779 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,19619755 0,2215953 ! ceramide metabolic process GO:0006672 72 35 0,000 0,19619755 0,2214929 ! telencephalon development GO:0021537 81 35 0,000 0,19619755 0,22139059 ! sterol transport GO:0015918 63 35 0,000 0,19619755 0,22128838 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,19619755 0,22118626 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,19619755 0,22108424 ! placenta development GO:0001890 53 35 0,000 0,19619755 0,22098231 ! vesicle localization GO:0051648 70 35 0,000 0,19619755 0,22088047 ! regulation of muscle development GO:0048634 82 36 0,000 0,20120024 0,22640819 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,20120024 0,22630395 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,20120024 0,22619981 ! positive regulation of cell development GO:0010720 85 36 0,000 0,20120024 0,22609576 ! protein targeting to membrane GO:0006612 75 36 0,000 0,20120024 0,22599181 ! regulation of proteolysis GO:0030162 77 36 0,000 0,20120024 0,22588795 ! aerobic respiration GO:0009060 56 36 0,000 0,20120024 0,22578419 ! cytokine production GO:0001816 68 36 0,000 0,20120024 0,22568053 ! embryonic organ development GO:0048568 67 36 0,000 0,20120024 0,22557695 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,20120024 0,22547348 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,20617193 0,23093903 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,20617193 0,23083319 ! odontogenesis GO:0042476 74 37 0,000 0,20617193 0,23072745 ! actomyosin structure organization GO:0031032 68 37 0,000 0,20617193 0,2306218 ! cell junction organization GO:0034330 96 37 0,000 0,20617193 0,23051626 ! tissue remodeling GO:0048771 78 37 0,000 0,20617193 0,23041081 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,20617193 0,23030545 ! female gonad development GO:0008585 71 37 0,000 0,20617193 0,23020019 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,20617193 0,23009503 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,20617193 0,22998996 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,21111281 0,23539416 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,21111281 0,23528677 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,21111281 0,23517948 ! organic anion transport GO:0015711 82 38 0,000 0,21111281 0,23507229 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,21111281 0,2349652 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,21111281 0,2348582 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,21111281 0,2347513 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,21111281 0,2346445 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,21111281 0,23453779 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,21111281 0,23443118 ! spermatid development GO:0007286 69 38 0,000 0,21111281 0,23432467 ! glycogen metabolic process GO:0005977 63 38 0,000 0,21111281 0,23421826 ! pigment metabolic process GO:0042440 87 38 0,000 0,21111281 0,23411194 ! neural tube formation GO:0001841 79 38 0,000 0,21111281 0,23400572 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,21602308 0,23933986 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,21602308 0,23923137 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,21602308 0,23912297 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,21602308 0,23901467 GO:0042593|glucose homeostasis, ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,21602308 0,23890647 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,21602308 0,23879837 ! glucan metabolic process GO:0044042 64 39 0,000 0,21602308 0,23869036 GO:0006073|cellular glucan metabolic process, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,22090293 0,24397191 ! learning GO:0007612 82 40 0,000 0,22090293 0,24386166 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,22090293 0,24375152 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,22090293 0,24364147 ! mismatch repair GO:0006298 58 40 0,000 0,22090293 0,24353152 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,22090293 0,24342168 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,22090293 0,24331193 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,22090293 0,24320228 ! RNA export from nucleus GO:0006405 61 41 0,000 0,22575254 0,24842948 ! mRNA catabolic process GO:0006402 79 41 0,000 0,22575254 0,24831763 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,22575254 0,24820587 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,22575254 0,24809422 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,22575254 0,24798266 ! gliogenesis GO:0042063 91 41 0,000 0,22575254 0,24787121 ! feeding behavior GO:0007631 69 41 0,000 0,22575254 0,24775986 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,22575254 0,24764861 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,22575254 0,24753745 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,22575254 0,2474264 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,22575254 0,24731545 ! spermatid differentiation GO:0048515 73 41 0,000 0,22575254 0,24720459 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,22575254 0,24709384 ! RNA modification GO:0009451 64 41 0,000 0,22575254 0,24698318 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,23057209 0,25214307 ! ear morphogenesis GO:0042471 64 42 0,000 0,23057209 0,25203026 ! organic ether metabolic process GO:0018904 59 42 0,000 0,23057209 0,25191754 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,23057209 0,25180493 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,23057209 0,25169241 ! regulation of protein secretion GO:0050708 77 42 0,000 0,23057209 0,25158 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,23057209 0,25146769 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,23536178 0,2565769 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,23536178 0,25646246 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,23536178 0,25634812 ! regulation of tube size GO:0035150 76 43 0,000 0,23536178 0,25623388 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,23536178 0,25611975 ! glucose transport GO:0015758 66 43 0,000 0,23536178 0,25600571 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,23536178 0,25589178 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,23536178 0,25577795 ! ion transmembrane transport GO:0034220 79 43 0,000 0,23536178 0,25566422 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,24012179 0,2607189 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,24012179 0,26060308 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,24012179 0,26048736 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,24012179 0,26037174 ! hexose transport GO:0008645 68 44 0,000 0,24012179 0,26025623 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,24012179 0,26014081 ! striated muscle contraction GO:0006941 85 44 0,000 0,24012179 0,2600255 ! phagocytosis GO:0006909 105 44 0,000 0,24012179 0,25991029 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,24012179 0,25979519 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,2448523 0,264796 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,2448523 0,26467884 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,2448523 0,26456177 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,2448523 0,26444481 ! female gamete generation GO:0007292 71 45 0,000 0,2448523 0,26432796 ! polyol metabolic process GO:0019751 77 45 0,000 0,2448523 0,2642112 ! developmental growth GO:0048589 88 45 0,000 0,2448523 0,26409456 ! maintenance of location in cell GO:0051651 101 45 0,000 0,2448523 0,26397801 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,24955349 0,26892774 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,24955349 0,26880916 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,24955349 0,26869069 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,24955349 0,26857233 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,24955349 0,26845406 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,24955349 0,26833591 ! neural tube development GO:0021915 91 47 0,000 0,25422555 0,27323934 ! positive regulation of defense response GO:0031349 88 48 0,000 0,25886865 0,27810735 ! mitochondrial transport GO:0006839 94 48 0,000 0,25886865 0,2779851 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,25886865 0,27786297 ! endosome transport GO:0016197 127 48 0,000 0,25886865 0,27774094 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,25886865 0,27761901 ! male sex differentiation GO:0046661 93 48 0,000 0,25886865 0,2774972 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,25886865 0,27737549 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,25886865 0,27725389 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,25886865 0,27713239 ! methylation GO:0032259 97 48 0,000 0,25886865 0,277011 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,26348297 0,28182526 ! JNK cascade GO:0007254 106 49 0,000 0,26348297 0,28170193 ! protein homooligomerization GO:0051260 84 49 0,000 0,26348297 0,2815787 ! regulation of action potential GO:0001508 102 50 0,000 0,2680687 0,2863541 ! regulation of ion transport GO:0043269 86 50 0,000 0,2680687 0,28622895 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,2680687 0,2861039 ! regulation of ossification GO:0030278 123 50 0,000 0,2680687 0,28597896 ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,2680687 0,28585414 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,2680687 0,28572942 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,272626 0,29046023 ! peptide metabolic process GO:0006518 80 51 0,000 0,272626 0,29033361 ! response to temperature stimulus GO:0009266 84 51 0,000 0,272626 0,29020711 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,272626 0,29008071 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,27715505 0,29477135 ! Notch signaling pathway GO:0007219 111 52 0,000 0,27715505 0,29464308 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,27715505 0,29451491 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,27715505 0,29438686 ! excretion GO:0007588 87 52 0,000 0,27715505 0,29425893 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,27715505 0,2941311 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,27715505 0,29400338 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,27715505 0,29387578 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,27715505 0,29374828 ! amino acid activation GO:0043038 98 52 0,000 0,27715505 0,2936209 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,28165603 0,29825994 ! inner ear development GO:0048839 89 53 0,000 0,28165603 0,29813071 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,28165603 0,29800159 ! vesicle organization GO:0016050 127 53 0,000 0,28165603 0,29787259 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,28165603 0,29774369 ! cartilage development GO:0051216 99 53 0,000 0,28165603 0,29761491 ! synapse organization GO:0050808 102 53 0,000 0,28165603 0,29748624 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,28612911 0,30208012 ! regulation of translational initiation GO:0006446 87 54 0,000 0,28612911 0,30194964 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,28612911 0,30181926 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,28612911 0,301689 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,28612911 0,30155885 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,28612911 0,30142881 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,28612911 0,30129888 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,28612911 0,30116907 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,28612911 0,30103937 ! RNA catabolic process GO:0006401 103 55 0,000 0,29057446 0,30558476 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,29057446 0,30545327 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,29057446 0,30532189 ! cell recognition GO:0008037 98 55 0,000 0,29057446 0,30519063 ! cell maturation GO:0048469 107 55 0,000 0,29057446 0,30505947 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,29057446 0,30492844 ! regulation of DNA replication GO:0006275 105 56 0,000 0,29499225 0,30943154 ! RNA elongation GO:0006354 90 56 0,000 0,29499225 0,30929874 ! chloride transport GO:0006821 102 57 0,000 0,29938266 0,31376741 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,29938266 0,31363286 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,29938266 0,31349843 ! heart morphogenesis GO:0003007 105 57 0,000 0,29938266 0,31336411 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,29938266 0,3132299 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,30374584 0,31765886 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,30374584 0,31752293 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,30374584 0,31738712 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,30374584 0,31725143 ! gastrulation GO:0007369 122 58 0,000 0,30374584 0,31711585 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,30374584 0,31698039 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,30374584 0,31684504 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,30374584 0,31670981 ! maintenance of location GO:0051235 124 58 0,000 0,30374584 0,3165747 ! nuclear export GO:0051168 110 59 0,000 0,30808198 0,32095705 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,31239123 0,32530767 ! regulation of endocytosis GO:0030100 104 60 0,000 0,31239123 0,32516906 ! positive regulation of secretion GO:0051047 110 61 0,000 0,31667377 0,32948638 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,31667377 0,32934611 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,31667377 0,32920597 ! camera-type eye development GO:0043010 126 61 0,000 0,31667377 0,32906594 ! proton transport GO:0015992 117 61 0,000 0,31667377 0,32892603 ! tRNA processing GO:0008033 102 62 0,000 0,32092976 0,33320501 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,32092976 0,33306346 ! mesoderm development GO:0007498 128 63 0,000 0,32515935 0,33730968 ! hydrogen transport GO:0006818 121 64 0,000 0,32936272 0,3415251 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,32936272 0,3413802 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,33354003 0,34556331 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,33354003 0,34541682 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,33354003 0,34527046 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,33354003 0,34512422 ! ear development GO:0043583 114 66 0,000 0,33769143 0,34927187 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,33769143 0,34912407 ! gonad development GO:0008406 115 66 0,000 0,33769143 0,34897638 ! activation of MAPK activity GO:0000187 124 67 0,000 0,34181709 0,35309055 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,34181709 0,35294132 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,34181709 0,35279221 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,34181709 0,35264323 ! extracellular matrix organization GO:0030198 146 68 0,000 0,34591717 0,35672252 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,34591717 0,356572 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,34999182 0,36062 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,34999182 0,36046797 ! developmental maturation GO:0021700 128 69 0,000 0,34999182 0,36031606 ! single fertilization GO:0007338 83 69 0,000 0,34999182 0,36016429 ! germ cell development GO:0007281 133 70 0,000 0,3540412 0,36417796 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,35806547 0,36816243 ! appendage morphogenesis GO:0035107 150 72 0,000 0,36206478 0,3721179 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,36206478 0,37196142 ! actin filament organization GO:0007015 167 72 0,000 0,36206478 0,37180507 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,36206478 0,37164885 ! appendage development GO:0048736 151 73 0,000 0,36603929 0,37557076 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,36603929 0,37541309 ! amino acid transport GO:0006865 148 74 0,000 0,36998914 0,37930486 ! transition metal ion transport GO:0000041 143 75 0,000 0,3739145 0,38316825 ! reproductive structure development GO:0048608 131 75 0,000 0,3739145 0,3830076 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,3739145 0,38284707 ! eye development GO:0001654 155 75 0,000 0,3739145 0,38268669 ! axon guidance GO:0007411 162 75 0,000 0,3739145 0,38252643 ! rhythmic process GO:0048511 142 75 0,000 0,3739145 0,38236631 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,37781551 0,38619384 ! learning or memory GO:0007611 161 76 0,000 0,37781551 0,38603232 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,37781551 0,38587094 ! regulation of blood pressure GO:0008217 134 76 0,000 0,37781551 0,38570969 ! neurotransmitter transport GO:0006836 142 77 0,000 0,38169232 0,38950474 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,38169232 0,3893421 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,38169232 0,38917961 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,38554508 0,39294395 ! fertilization GO:0009566 99 78 0,000 0,38554508 0,39278008 ! blood coagulation GO:0007596 151 79 0,000 0,38937395 0,39651545 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,38937395 0,39635023 ! protein oligomerization GO:0051259 149 79 0,000 0,38937395 0,39618516 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,38937395 0,39602022 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,39317906 0,39972387 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,39696057 0,40340045 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,40071862 0,40705014 ! exocytosis GO:0006887 153 83 0,000 0,40445336 0,41067313 ! response to drug GO:0042493 149 83 0,000 0,40445336 0,41050251 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,40445336 0,41033204 ! inorganic anion transport GO:0015698 156 83 0,000 0,40445336 0,41016171 ! digestion GO:0007586 130 84 0,000 0,40816492 0,4137539 ! hemostasis GO:0007599 165 85 0,000 0,41185346 0,41731979 ! negative regulation of transport GO:0051051 164 85 0,000 0,41185346 0,41714677 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,41185346 0,41697389 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,41185346 0,41680116 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,41185346 0,41662857 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,41916202 0,42384637 ! regulation of protein transport GO:0051223 165 87 0,000 0,41916202 0,42367101 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,42278233 0,42715353 ! sensory perception of smell GO:0007608 117 88 0,000 0,42278233 0,42697694 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,42278233 0,42680051 ! tube morphogenesis GO:0035239 194 89 0,000 0,42638017 0,43025475 ! cellular defense response GO:0006968 123 89 0,000 0,42638017 0,43007711 ! regulation of neurological system process GO:0031644 175 89 0,000 0,42638017 0,42989961 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,42995569 0,4333258 ! response to unfolded protein GO:0006986 139 90 0,000 0,42995569 0,43314711 ! ossification GO:0001503 205 91 0,000 0,43350902 0,4365468 ! bone development GO:0060348 206 92 0,000 0,4370403 0,43992149 ! amine transport GO:0015837 181 93 0,000 0,44054967 0,44327135 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,44054967 0,44308886 ! female pregnancy GO:0007565 166 94 0,000 0,44403726 0,44641276 ! sterol metabolic process GO:0016125 166 94 0,000 0,44403726 0,44622913 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,44403726 0,44604565 ! regulation of membrane potential GO:0042391 179 94 0,000 0,44403726 0,44586232 ! regulation of defense response GO:0031347 171 95 0,000 0,4475032 0,4491579 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,4475032 0,44897344 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,4475032 0,44878913 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,4475032 0,44860497 ! sex differentiation GO:0007548 171 96 0,000 0,45094764 0,45187247 ! response to protein stimulus GO:0051789 158 96 0,000 0,45094764 0,4516872 ! transcription initiation GO:0006352 171 97 0,000 0,4543707 0,45492935 ! regulation of protein localization GO:0032880 188 97 0,000 0,4543707 0,45474298 ! mRNA transport GO:0051028 185 100 0,000 0,46451292 0,46470314 ! hormone metabolic process GO:0042445 171 100 0,000 0,46451292 0,46451292